LOCUS       DAFBSV010000001       124785 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.001, whole genome shotgun sequence.
ACCESSION   DAFBSV010000001 DAFBSV010000000
VERSION     DAFBSV010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 124785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 124785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..124785
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.001"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            120..983
                     /locus_tag="LLB18_000001"
     CDS             120..983
                     /locus_tag="LLB18_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBK5243037.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1112..2734)
                     /locus_tag="LLB18_000002"
     CDS             complement(1112..2734)
                     /locus_tag="LLB18_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK5243038.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEDDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            2983..3504
                     /locus_tag="LLB18_000003"
     CDS             2983..3504
                     /locus_tag="LLB18_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBK5243039.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(3690..5420)
                     /gene="spxB"
                     /locus_tag="LLB18_000004"
     CDS             complement(3690..5420)
                     /gene="spxB"
                     /locus_tag="LLB18_000004"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HBK5243040.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5585..6403
                     /locus_tag="LLB18_000005"
     CDS             5585..6403
                     /locus_tag="LLB18_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBK5243041.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6506..6703)
                     /locus_tag="LLB18_000006"
     CDS             complement(6506..6703)
                     /locus_tag="LLB18_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243042.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            6872..7450
                     /locus_tag="LLB18_000007"
     CDS             6872..7450
                     /locus_tag="LLB18_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBK5243043.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7545..7682
                     /locus_tag="LLB18_000008"
     CDS             7545..7682
                     /locus_tag="LLB18_000008"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243044.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(8495..8998)
                     /locus_tag="LLB18_000009"
     CDS             complement(8495..8998)
                     /locus_tag="LLB18_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBK5243045.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9357..10382
                     /locus_tag="LLB18_000010"
     CDS             9357..10382
                     /locus_tag="LLB18_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBK5243046.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            10729..11607
                     /locus_tag="LLB18_000011"
     CDS             10729..11607
                     /locus_tag="LLB18_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HBK5243047.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12083..12199
                     /locus_tag="LLB18_000012"
     CDS             12083..12199
                     /locus_tag="LLB18_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBK5243048.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13127..13465
                     /locus_tag="LLB18_000013"
     CDS             13127..13465
                     /locus_tag="LLB18_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243049.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13559..13789
                     /locus_tag="LLB18_000014"
     CDS             13559..13789
                     /locus_tag="LLB18_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243050.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14189..14560
                     /locus_tag="LLB18_000015"
     CDS             14189..14560
                     /locus_tag="LLB18_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBK5243051.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(14834..15526)
                     /locus_tag="LLB18_000016"
     CDS             complement(14834..15526)
                     /locus_tag="LLB18_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBK5243052.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(15529..16314)
                     /locus_tag="LLB18_000017"
     CDS             complement(15529..16314)
                     /locus_tag="LLB18_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBK5243053.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            16551..17951
                     /gene="lacG"
                     /locus_tag="LLB18_000018"
     CDS             16551..17951
                     /gene="lacG"
                     /locus_tag="LLB18_000018"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBK5243054.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            17976..18293
                     /locus_tag="LLB18_000019"
     CDS             17976..18293
                     /locus_tag="LLB18_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBK5243055.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18306..19979
                     /locus_tag="LLB18_000020"
     CDS             18306..19979
                     /locus_tag="LLB18_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HBK5243056.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            19993..21624
                     /locus_tag="LLB18_000021"
     CDS             19993..21624
                     /locus_tag="LLB18_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HBK5243057.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            22496..23686
                     /locus_tag="LLB18_000022"
     CDS             22496..23686
                     /locus_tag="LLB18_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HBK5243058.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFNGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGTFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            23820..26009
                     /locus_tag="LLB18_000023"
     CDS             23820..26009
                     /locus_tag="LLB18_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK5243059.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            26006..27799
                     /locus_tag="LLB18_000024"
     CDS             26006..27799
                     /locus_tag="LLB18_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBK5243060.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFT
                     ESGEKVRRRKLIANDILIILKNEFGIEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLY
                     KFVTKHIFVNLNIDEKNYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGI
                     TLTTAHKVKGNEYDTVIAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNL
                     FLFSEVGYFTSKGDLLYPTQLLDKIEFDYNI"
     gene            27999..28313
                     /locus_tag="LLB18_000025"
     CDS             27999..28313
                     /locus_tag="LLB18_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBK5243061.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            28334..28711
                     /locus_tag="LLB18_000026"
     CDS             28334..28711
                     /locus_tag="LLB18_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBK5243062.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            28721..29494
                     /locus_tag="LLB18_000027"
     CDS             28721..29494
                     /locus_tag="LLB18_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243063.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            29516..30919
                     /locus_tag="LLB18_000028"
     CDS             29516..30919
                     /locus_tag="LLB18_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBK5243064.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            31101..32285
                     /locus_tag="LLB18_000029"
     CDS             31101..32285
                     /locus_tag="LLB18_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBK5243065.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            32282..32572
                     /locus_tag="LLB18_000030"
     CDS             32282..32572
                     /locus_tag="LLB18_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243066.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            32569..32790
                     /locus_tag="LLB18_000031"
     CDS             32569..32790
                     /locus_tag="LLB18_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243067.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            32832..33611
                     /locus_tag="LLB18_000032"
     CDS             32832..33611
                     /locus_tag="LLB18_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HBK5243068.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            33678..34172
                     /locus_tag="LLB18_000033"
     CDS             33678..34172
                     /locus_tag="LLB18_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBK5243069.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            34228..34866
                     /locus_tag="LLB18_000034"
     CDS             34228..34866
                     /locus_tag="LLB18_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243070.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            34938..35333
                     /locus_tag="LLB18_000035"
     CDS             34938..35333
                     /locus_tag="LLB18_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK5243071.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            35317..37770
                     /locus_tag="LLB18_000036"
     CDS             35317..37770
                     /locus_tag="LLB18_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK5243072.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            37767..39794
                     /locus_tag="LLB18_000037"
     CDS             37767..39794
                     /locus_tag="LLB18_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243073.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            39791..40813
                     /locus_tag="LLB18_000038"
     CDS             39791..40813
                     /locus_tag="LLB18_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBK5243074.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDGETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            40830..41759
                     /locus_tag="LLB18_000039"
     CDS             40830..41759
                     /locus_tag="LLB18_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK5243075.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            42011..43930
                     /gene="tet(M)"
                     /locus_tag="LLB18_000040"
     CDS             42011..43930
                     /gene="tet(M)"
                     /locus_tag="LLB18_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HBK5243076.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIV
                     NTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRL
                     NSRIDKVRYMFNKIT"
     gene            44028..44216
                     /locus_tag="LLB18_000041"
     CDS             44028..44216
                     /locus_tag="LLB18_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBK5243077.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(44274..44627)
                     /locus_tag="LLB18_000042"
     CDS             complement(44274..44627)
                     /locus_tag="LLB18_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5243078.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            45158..45580
                     /locus_tag="LLB18_000043"
     CDS             45158..45580
                     /locus_tag="LLB18_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK5243079.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            45577..45807
                     /locus_tag="LLB18_000044"
     CDS             45577..45807
                     /locus_tag="LLB18_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5243080.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            46305..46505
                     /locus_tag="LLB18_000045"
     CDS             46305..46505
                     /locus_tag="LLB18_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBK5243081.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            46532..47725
                     /locus_tag="LLB18_000046"
     CDS             46532..47725
                     /locus_tag="LLB18_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBK5243082.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(47793..49358)
                     /gene="guaA"
                     /locus_tag="LLB18_000047"
     CDS             complement(47793..49358)
                     /gene="guaA"
                     /locus_tag="LLB18_000047"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBK5243083.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(49417..50340)
                     /locus_tag="LLB18_000048"
     CDS             complement(49417..50340)
                     /locus_tag="LLB18_000048"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HBK5243084.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            50536..51141
                     /locus_tag="LLB18_000049"
     CDS             50536..51141
                     /locus_tag="LLB18_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBK5243085.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            51449..52465
                     /locus_tag="LLB18_000050"
     CDS             51449..52465
                     /locus_tag="LLB18_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBK5243086.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            52606..53907
                     /locus_tag="LLB18_000051"
     CDS             52606..53907
                     /locus_tag="LLB18_000051"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBK5243087.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            53953..54615
                     /gene="deoC"
                     /locus_tag="LLB18_000052"
     CDS             53953..54615
                     /gene="deoC"
                     /locus_tag="LLB18_000052"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBK5243088.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            54636..55034
                     /locus_tag="LLB18_000053"
     CDS             54636..55034
                     /locus_tag="LLB18_000053"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBK5243089.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            55100..56182
                     /locus_tag="LLB18_000054"
     CDS             55100..56182
                     /locus_tag="LLB18_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK5243090.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            56394..57956
                     /locus_tag="LLB18_000055"
     CDS             56394..57956
                     /locus_tag="LLB18_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5243091.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            57949..59082
                     /locus_tag="LLB18_000056"
     CDS             57949..59082
                     /locus_tag="LLB18_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5243092.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            59082..60038
                     /locus_tag="LLB18_000057"
     CDS             59082..60038
                     /locus_tag="LLB18_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5243093.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            60137..61303
                     /gene="deoB"
                     /locus_tag="LLB18_000058"
     CDS             60137..61303
                     /gene="deoB"
                     /locus_tag="LLB18_000058"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBK5243094.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            61327..62145
                     /locus_tag="LLB18_000059"
     CDS             61327..62145
                     /locus_tag="LLB18_000059"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBK5243095.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            62162..62869
                     /gene="deoD"
                     /locus_tag="LLB18_000060"
     CDS             62162..62869
                     /gene="deoD"
                     /locus_tag="LLB18_000060"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBK5243096.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(63167..63853)
                     /gene="gpmA"
                     /locus_tag="LLB18_000061"
     CDS             complement(63167..63853)
                     /gene="gpmA"
                     /locus_tag="LLB18_000061"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBK5243097.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(64025..64606)
                     /locus_tag="LLB18_000062"
     CDS             complement(64025..64606)
                     /locus_tag="LLB18_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBK5243098.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(64739..65422)
                     /gene="rpiA"
                     /locus_tag="LLB18_000063"
     CDS             complement(64739..65422)
                     /gene="rpiA"
                     /locus_tag="LLB18_000063"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HBK5243099.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            65741..66154
                     /gene="rpsL"
                     /locus_tag="LLB18_000064"
     CDS             65741..66154
                     /gene="rpsL"
                     /locus_tag="LLB18_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBK5243100.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            66238..66708
                     /gene="rpsG"
                     /locus_tag="LLB18_000065"
     CDS             66238..66708
                     /gene="rpsG"
                     /locus_tag="LLB18_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBK5243101.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            66802..68889
                     /gene="fusA"
                     /locus_tag="LLB18_000066"
     CDS             66802..68889
                     /gene="fusA"
                     /locus_tag="LLB18_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBK5243102.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            69061..70248
                     /gene="tuf"
                     /locus_tag="LLB18_000067"
     CDS             69061..70248
                     /gene="tuf"
                     /locus_tag="LLB18_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBK5243103.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            70655..70963
                     /gene="rpsJ"
                     /locus_tag="LLB18_000068"
     CDS             70655..70963
                     /gene="rpsJ"
                     /locus_tag="LLB18_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBK5243104.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            70994..71623
                     /gene="rplC"
                     /locus_tag="LLB18_000069"
     CDS             70994..71623
                     /gene="rplC"
                     /locus_tag="LLB18_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBK5243105.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            71651..72274
                     /gene="rplD"
                     /locus_tag="LLB18_000070"
     CDS             71651..72274
                     /gene="rplD"
                     /locus_tag="LLB18_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBK5243106.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            72274..72564
                     /gene="rplW"
                     /locus_tag="LLB18_000071"
     CDS             72274..72564
                     /gene="rplW"
                     /locus_tag="LLB18_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBK5243107.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            72603..73436
                     /gene="rplB"
                     /locus_tag="LLB18_000072"
     CDS             72603..73436
                     /gene="rplB"
                     /locus_tag="LLB18_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBK5243108.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            73479..73757
                     /gene="rpsS"
                     /locus_tag="LLB18_000073"
     CDS             73479..73757
                     /gene="rpsS"
                     /locus_tag="LLB18_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBK5243109.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            73780..74127
                     /gene="rplV"
                     /locus_tag="LLB18_000074"
     CDS             73780..74127
                     /gene="rplV"
                     /locus_tag="LLB18_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBK5243110.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            74141..74797
                     /gene="rpsC"
                     /locus_tag="LLB18_000075"
     CDS             74141..74797
                     /gene="rpsC"
                     /locus_tag="LLB18_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBK5243111.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            74800..75234
                     /gene="rplP"
                     /locus_tag="LLB18_000076"
     CDS             74800..75234
                     /gene="rplP"
                     /locus_tag="LLB18_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBK5243112.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            75224..75412
                     /gene="rpmC"
                     /locus_tag="LLB18_000077"
     CDS             75224..75412
                     /gene="rpmC"
                     /locus_tag="LLB18_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBK5243113.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            75437..75703
                     /gene="rpsQ"
                     /locus_tag="LLB18_000078"
     CDS             75437..75703
                     /gene="rpsQ"
                     /locus_tag="LLB18_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBK5243114.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            75761..76129
                     /gene="rplN"
                     /locus_tag="LLB18_000079"
     CDS             75761..76129
                     /gene="rplN"
                     /locus_tag="LLB18_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBK5243115.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            76166..76474
                     /gene="rplX"
                     /locus_tag="LLB18_000080"
     CDS             76166..76474
                     /gene="rplX"
                     /locus_tag="LLB18_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBK5243116.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            76502..77041
                     /gene="rplE"
                     /locus_tag="LLB18_000081"
     CDS             76502..77041
                     /gene="rplE"
                     /locus_tag="LLB18_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBK5243117.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            77060..77245
                     /locus_tag="LLB18_000082"
     CDS             77060..77245
                     /locus_tag="LLB18_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBK5243118.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            77281..77679
                     /gene="rpsH"
                     /locus_tag="LLB18_000083"
     CDS             77281..77679
                     /gene="rpsH"
                     /locus_tag="LLB18_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBK5243119.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            77711..78247
                     /gene="rplF"
                     /locus_tag="LLB18_000084"
     CDS             77711..78247
                     /gene="rplF"
                     /locus_tag="LLB18_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBK5243120.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            78408..78764
                     /gene="rplR"
                     /locus_tag="LLB18_000085"
     CDS             78408..78764
                     /gene="rplR"
                     /locus_tag="LLB18_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBK5243121.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            78785..79285
                     /gene="rpsE"
                     /locus_tag="LLB18_000086"
     CDS             78785..79285
                     /gene="rpsE"
                     /locus_tag="LLB18_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBK5243122.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            79300..79479
                     /gene="rpmD"
                     /locus_tag="LLB18_000087"
     CDS             79300..79479
                     /gene="rpmD"
                     /locus_tag="LLB18_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBK5243123.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            79523..79963
                     /gene="rplO"
                     /locus_tag="LLB18_000088"
     CDS             79523..79963
                     /gene="rplO"
                     /locus_tag="LLB18_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBK5243124.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            79963..81258
                     /gene="secY"
                     /locus_tag="LLB18_000089"
     CDS             79963..81258
                     /gene="secY"
                     /locus_tag="LLB18_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBK5243125.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            81320..81967
                     /locus_tag="LLB18_000090"
     CDS             81320..81967
                     /locus_tag="LLB18_000090"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBK5243126.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            82158..82376
                     /gene="infA"
                     /locus_tag="LLB18_000091"
     CDS             82158..82376
                     /gene="infA"
                     /locus_tag="LLB18_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBK5243127.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            82409..82525
                     /gene="rpmJ"
                     /locus_tag="LLB18_000092"
     CDS             82409..82525
                     /gene="rpmJ"
                     /locus_tag="LLB18_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBK5243128.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            82543..82908
                     /gene="rpsM"
                     /locus_tag="LLB18_000093"
     CDS             82543..82908
                     /gene="rpsM"
                     /locus_tag="LLB18_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBK5243129.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            82936..83325
                     /gene="rpsK"
                     /locus_tag="LLB18_000094"
     CDS             82936..83325
                     /gene="rpsK"
                     /locus_tag="LLB18_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBK5243130.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            83405..84343
                     /locus_tag="LLB18_000095"
     CDS             83405..84343
                     /locus_tag="LLB18_000095"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBK5243131.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            84371..84751
                     /gene="rplQ"
                     /locus_tag="LLB18_000096"
     CDS             84371..84751
                     /gene="rplQ"
                     /locus_tag="LLB18_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBK5243132.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            85023..85862
                     /locus_tag="LLB18_000097"
     CDS             85023..85862
                     /locus_tag="LLB18_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBK5243133.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            85838..86707
                     /locus_tag="LLB18_000098"
     CDS             85838..86707
                     /locus_tag="LLB18_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBK5243134.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            86697..87494
                     /locus_tag="LLB18_000099"
     CDS             86697..87494
                     /locus_tag="LLB18_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBK5243135.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            87697..88443
                     /gene="truA"
                     /locus_tag="LLB18_000100"
     CDS             87697..88443
                     /gene="truA"
                     /locus_tag="LLB18_000100"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBK5243136.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(88776..91445)
                     /locus_tag="LLB18_000101"
     CDS             complement(88776..91445)
                     /locus_tag="LLB18_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HBK5243137.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(91683..91871)
                     /locus_tag="LLB18_000102"
     CDS             complement(91683..91871)
                     /locus_tag="LLB18_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBK5243138.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            92141..92503
                     /locus_tag="LLB18_000103"
     CDS             92141..92503
                     /locus_tag="LLB18_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBK5243139.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            92555..94237
                     /locus_tag="LLB18_000104"
     CDS             92555..94237
                     /locus_tag="LLB18_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBK5243140.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            94354..96390
                     /gene="recG"
                     /locus_tag="LLB18_000105"
     CDS             94354..96390
                     /gene="recG"
                     /locus_tag="LLB18_000105"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBK5243141.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            96439..97440
                     /gene="plsX"
                     /locus_tag="LLB18_000106"
     CDS             96439..97440
                     /gene="plsX"
                     /locus_tag="LLB18_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBK5243142.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            97562..97804
                     /gene="acpP"
                     /locus_tag="LLB18_000107"
     CDS             97562..97804
                     /gene="acpP"
                     /locus_tag="LLB18_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBK5243143.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            98072..99076
                     /locus_tag="LLB18_000108"
     CDS             98072..99076
                     /locus_tag="LLB18_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5243144.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            99077..100021
                     /locus_tag="LLB18_000109"
     CDS             99077..100021
                     /locus_tag="LLB18_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5243145.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            100021..100983
                     /locus_tag="LLB18_000110"
     CDS             100021..100983
                     /locus_tag="LLB18_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5243146.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            101010..101924
                     /locus_tag="LLB18_000111"
     CDS             101010..101924
                     /locus_tag="LLB18_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5243147.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            101950..103731
                     /locus_tag="LLB18_000112"
     CDS             101950..103731
                     /locus_tag="LLB18_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK5243148.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            104079..104765
                     /locus_tag="LLB18_000113"
     CDS             104079..104765
                     /locus_tag="LLB18_000113"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBK5243149.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            104785..108366
                     /gene="smc"
                     /locus_tag="LLB18_000114"
     CDS             104785..108366
                     /gene="smc"
                     /locus_tag="LLB18_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBK5243150.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            108375..109184
                     /locus_tag="LLB18_000115"
     CDS             108375..109184
                     /locus_tag="LLB18_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBK5243151.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            109195..110193
                     /gene="ftsY"
                     /locus_tag="LLB18_000116"
     CDS             109195..110193
                     /gene="ftsY"
                     /locus_tag="LLB18_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBK5243152.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            110380..112647
                     /gene="gshAB"
                     /locus_tag="LLB18_000117"
     CDS             110380..112647
                     /gene="gshAB"
                     /locus_tag="LLB18_000117"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HBK5243153.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(112736..113188)
                     /locus_tag="LLB18_000118"
     CDS             complement(112736..113188)
                     /locus_tag="LLB18_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HBK5243154.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKSNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            113338..114288
                     /locus_tag="LLB18_000119"
     CDS             113338..114288
                     /locus_tag="LLB18_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBK5243155.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            114281..115240
                     /locus_tag="LLB18_000120"
     CDS             114281..115240
                     /locus_tag="LLB18_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBK5243156.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            115237..115992
                     /locus_tag="LLB18_000121"
     CDS             115237..115992
                     /locus_tag="LLB18_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK5243157.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            116015..116968
                     /locus_tag="LLB18_000122"
     CDS             116015..116968
                     /locus_tag="LLB18_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK5243158.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(117491..117787)
                     /locus_tag="LLB18_000123"
     CDS             complement(117491..117787)
                     /locus_tag="LLB18_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HBK5243159.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            118142..118498
                     /locus_tag="LLB18_000124"
     CDS             118142..118498
                     /locus_tag="LLB18_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBK5243160.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            118508..119407
                     /locus_tag="LLB18_000125"
     CDS             118508..119407
                     /locus_tag="LLB18_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HBK5243161.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            119924..120655
                     /locus_tag="LLB18_000126"
     CDS             119924..120655
                     /locus_tag="LLB18_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBK5243162.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            120800..122827
                     /locus_tag="LLB18_000127"
     CDS             120800..122827
                     /locus_tag="LLB18_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBK5243163.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            122935..124032
                     /locus_tag="LLB18_000128"
     CDS             122935..124032
                     /locus_tag="LLB18_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBK5243164.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            124339..>124785
                     /locus_tag="LLB18_000129"
     CDS             124339..>124785
                     /locus_tag="LLB18_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5243165.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRKL"
BASE COUNT        40936 a        21737 c        25987 g        36125 t
ORIGIN      
        1 tcacaacctc ttattttgat tagaacttgc gaaaataaac cggttaaagt gtgtctagcg
       61 caagagattt gctataatag acgataaggg taaaatgtaa cgagaagggg ttgaaaaatg
      121 tgtatcaaat tgtaacagat tcttgttgtg atctgccata ccatgtatta gcaaaagaaa
      181 aagttgattt tttatcaatg aatctccaat tgaatgatca agagttagta gatgacctcg
      241 gaaagacatt caattatgac cgctacatga atcagctgaa aaatggtgcg atgcctacga
      301 catcacaaat caatgttggc cgatatttag aatttttccg ttcttatgcg gaaaaacaga
      361 ttcctgtttt atatgtggct ttttccagtg gattaagcgg ctcttacagt agtgcgcttc
      421 aagcggttga attgctgaag gaagaatatg aagaccctga gatctatgtt tttgatacaa
      481 aagctgcaag tattggggaa gggcttttag tattggaagc tgtaagattg aaaaaagaag
      541 gtaaaagcat cgaagaaacc ctagagtggc tggaaagtaa ttatttgaaa gtccattcat
      601 gggtaacagt agacgatctg aaatatctag aacgaggcgg taggatttcc aaagcaagtg
      661 ctactcttgg cagtctattg agtgtaaagc ctattattac ggtggataaa gaaggaaggc
      721 tgacgaatgt tgacaaagtt cgaggaagaa acaagtcgat ccagacaatc gtcaatgaga
      781 cggtaaaaac aatcgttgca ccacttgatc aaatcgttta tgtggcttac gctggggatc
      841 tagagagcgc ggagaaggca aaacggcttt tggaagagca gataaagatg aaagatgtga
      901 agctttatcc cttaggacca acgatcgcca gtcacacagg ctatggctgt atcgcgattt
      961 tttcgatggg aatcagtcga taaaagcagt aactcattct gtaaaaaagc ccagaaattg
     1021 attgtaacaa aaacagcgac tcttaaaaga tagatgagca tcctatctct tagaggtcgc
     1081 tgttttttta ttttttaagc taaataggcc attatgccca taactcgttc aattgttttt
     1141 gaatatctgc attttccaaa aattcatcat atgtcgtatc agctcgatcg atcacacctt
     1201 tatccgaaac ggcaatgatg cggtttgcca atgtttggat aaattgatgg tcatgtgacg
     1261 caaataagat tgagccagta aatgccatca agccgtcatt caatgctgtg attgattcta
     1321 agtctaaatg gttcgttgga tcatctaata caagtacgtt agctttcgaa agcatcattt
     1381 ttgaaagcat gcaacggact ttctctccac cagataaaac attcactggt ttcaatactt
     1441 cttcaccaga aaacaacatt cttcctaaga agcttcttaa gaaggtgtta tcatcatctt
     1501 ctttacttgc atattgacgc aaccagtcta aaatcgttag atcagtatcg aattctttcg
     1561 ttgtatcctt tggtaaataa gaattacttg ttgtcacacc ccaacgtact gttccagtat
     1621 ctggcgtaat ttcacccatg ataactttga atagcgttgt tgttgttata tcattttctg
     1681 cgacgaaagc gaccttgtct tctttgctca aattaaaaga tatatcatct aaaattttct
     1741 ttccatcaat cgttacactt acattttcta cctgcaataa gtcgtttcca atctcacgtt
     1801 caggtttgaa tccaacgaat ggataacgtc tagaagaagg ttggatatcg tctaaagtaa
     1861 ttttttcaag cattttttta cgtgaagttg cttgttttga ttttgatgca ttcgcactaa
     1921 agcgggcaat aaattcttgg agttctttga tttgttcttc ttttttggca tttgcgtttg
     1981 cttgaagttt agccgctagt tgactagatt ccaaccaaaa atcataattt cctacataaa
     2041 gtttgatttt accaaaatct agatccgcca tatgtgtaca tactttgttc aaaaagtgac
     2101 ggtcatggga tacaacgatc acagtatttt caaaattgat caaaaattct tccagccaat
     2161 tgatcgattg gatatccaga ccgtttgttg gttcgtctag caaaagaaca tcaggtttac
     2221 caaatagtgt ttgtgctaat aacactttta ccttttgtcc accagttaat tcactcattt
     2281 gctgatggtg caattcttca gggatgttca gaccttgcag taaaacagct gcttctggtt
     2341 cagcttccca tccattaagc tcagcaaatt ctccttctaa ttcagctgct cgaataccat
     2401 cttcgtcagt gaaatcctct ttcatgtaaa tcgcatcttt ttctttcagc acttcataca
     2461 gacgcttgtg tcccatgatg actgtttcaa gtacagtata gtcttcatag tcgtaatggt
     2521 tctgtttcaa tacggccatc cgttcatctg gtcccatagt aacggaacct gtggaaggct
     2581 gcagatcccc tgataacact ttaaggaacg ttgatttacc tgcaccattt gcaccaatca
     2641 agccatagca gtttccgggg gtaaatttaa tattcacatc atcaaatagt ttgcggtctg
     2701 aaaagtgcaa actcacatca tttacagtaa tcaatttttt tcctcacttt tatcattatt
     2761 agttttgaca agtcttatag aattatatag gggaaaggta aaagattcaa ggcaatcgaa
     2821 cattctttgt gtttcacgtg aaacagaatg aaaaaaataa aaataaaagc ggagcgaaaa
     2881 tagctactat aggatttatt agtttgcaac agcataattt ttgacgttat ttataagagg
     2941 gagtactata aaactgtaaa agaaatgaaa gaaggattga aaatggatga aaaaagaacc
     3001 atcgactggg gctcattgat tttgggaatt ttatttgtac ttgtctcatt gttatcattt
     3061 caagaccctg tcggaaattt agttgcaatt gtagtagtct ttgcgatttt tgcctttatt
     3121 aaagggatat ttgaactgtt tgtacggaac agattaaaag agctaacagg atataaagga
     3181 aagatgccct taataatcgg gatcatcgat attctagttg gcgtcttttt cttattcaat
     3241 attggtgcag gagtcgcagc attgcctttt gtttttgcag tatggtttat tgctgattca
     3301 gttttagcgt tatttactgc tgacttggca agaggagtaa gtgaaggata ttattggttt
     3361 acgatcatcg tcaatatttt aggaatttta ttaggaattt tcttattgtt taatccaatt
     3421 tcttctgcgt tgacattaag ctttttagtt ggattctatt ttatgttatt tggtatcaca
     3481 catatcgtct atgcatttag ataagtaaaa tcaaacaaat aaaaaagccg gcttccgatt
     3541 acagttttac tgttgtaatt ggaagccggc ttttttatca tggacaaata tgcacgaggt
     3601 gatttttagg tgtcgagaca aatttatgca aaaatgtgag aagctatata cacaaatttt
     3661 atcttaatac tcgaagcata gcgcagttgt cacaacctct tttcatataa ttcattcaat
     3721 actggcaaat catggacttc atatttttct ttgaatgctt ggatttcttc ttcagaatat
     3781 tttcttggat ctaaatgcag atcttctact ggcaatgggc gcttgttatt gatcttcaca
     3841 tcgattacta caggacgatc tgattttgca gctgcatcaa aggcaaatcg aagttgcgag
     3901 tattctgtga ctgtaaagct atttgccccg agcgcttctc caactttacc gaaatctgca
     3961 tcttctaaaa atacaccaaa tttcttttgt tccgtatctt cttgttctgc ttcgatgaaa
     4021 ccaaaagaat cattcgaaaa gacaacatta ataattggaa gctgatattt gacttgtgta
     4081 atgatatctt gcatgaccat agcaaacccg ccatcaccac ttaaggtaaa tacttgtttt
     4141 tctgggtagc ttagttgtgc ggcaattcct cctggcacac cattacccat agttgcgaac
     4201 catccagatg tcgtatgttt ttgtttaccg ttcatattca ataaacgaat agaatggata
     4261 gtcgtgttac cgacatctgt gacgaaaatc gcatcgtctt cagcaatacg attgatttct
     4321 ttatagacag cctctggacg aatcggttct tcctctcgat cttcaaaaga tttcaaccaa
     4381 tttacccatt tttctttatt ttcttgattt gctaggtacc agctatcagc agggcgagca
     4441 tcccctaact cgacaagtct ttgcaaagct gtgtttgcat caccgaggat cgacaaagat
     4501 gtttcatggc gtcgtccaaa ttttgacgca tcgatatcga tttggataaa ttcagcagtt
     4561 ggattaaaaa atgcacgtcc aaatgggaag tcgctaccga caaataagat cagatcggct
     4621 tctgccaatg cttcatttcc gggtttagta gcgacacgtc cagcaaaacc aagaaagttt
     4681 tcataatcat caggaataat tccttttgct agaacggaag cgacaacagg aactgaaaaa
     4741 tgttctgaga attctttgat ttgcggaaat ccgtttcgcg ttccttgacc aacataaaga
     4801 actggttttt ttgctttttc aagataaggc aaagcagcta gcaaatcttt ttcttctggt
     4861 aatatcacac ttgttttgtg agtgtgagcg gtggagaaag gttgttcgtc aatttcttca
     4921 aaaccaagat caacagggat agtcacgata gccacgcctt tatgctcata ggcggcttta
     4981 atggcttcat ctactacatg cggaagactt tgtggtgtca tgactgtacg attgtatacg
     5041 ctaacatctg cgaaaatagg attttcattt agttcctgga aagagttata gttcatggat
     5101 gtagaagcaa cttgtcctaa gaacgctact agaggcacat ggtccatctg tgcatcatac
     5161 aaaccattga tcaaatgtgt cgcaccaggt cctgcagagc cgaagacagc gccgactttc
     5221 cccgttaatt ttgcatctgc agcggctgcg agtgcgccga cttcttcatg acgaacttga
     5281 atgtagttga tttcggtttt ttcttgatat agcgcatcca taattgaatt gaaagatcct
     5341 ccgggaatgc cgtaaatatg gtcgataccc cagctttcaa gaacttttac cattgcgatt
     5401 cctgcattga tttttgacat ggtgtttcac tcctttagca atgatgatac ataaattttt
     5461 tgtatctaga gtatagaact ttttatcgaa aatcccaact aattcgtctt ttcacaaaaa
     5521 tgtagtcatg tttttgggaa tatgctagag tagtacatag atagattcaa gagaggggaa
     5581 tggcatggtt gaatggctat tgagacttga accttggcag caagcacttg ctgggacagc
     5641 ttttacttat tttatgacag ctcttggtgc cgggttggtt tttttcttta aagaaatcaa
     5701 aaaagaagtg ctaaacttga tgttaggatt tgcttctggt gtcatgattg ctgcaagttt
     5761 ttggtctttg ttagatccgg ctattacaaa agcagaagaa aatggagata ttgcttggct
     5821 agttgtaagt attgggtttg gtttaggcgg tgtgttttta tatatggcag ataaaacact
     5881 gccccatatg cattttggac cacaacatga agcagaagga ttgcctaccc atttaaaacg
     5941 gacgatcttg cttgtttttt ctattacatt gcataacatt cctgaaggtt tagccgtggg
     6001 ggtagcattc ggtgcagcag caactgcgga taatccgaca gccgctatat tagccgctgt
     6061 ttcggtggcg ctaggtattg gtatccaaaa cttcccagaa ggagcagctg tatcaatccc
     6121 gttgcgacaa gaaggtctga gtcgtaaaaa ggcctttgtt tacggacaag cttctggaat
     6181 cgttgaacca attgctggag tgattggagc gctactagta acgaaagtgg agctgctgct
     6241 tccttatgca cttgcttttg ccgcaggagc aatgatttat gtcgtggtgg aagaattgat
     6301 ccctgaagca cagcagacat tgtccagcaa acgtcatttt gcagtttttg gcgtcatgag
     6361 tggatttatc attatgatga ttttggatgt ggcattagga taaataaaaa aaatatatat
     6421 gatatatcaa atagggccgc gaacttatat cgcgacccta tttttttagt aagttatatc
     6481 ataatgaagt gaatggtatc atacattaat aatagttttt tctatgtgta tttcctttga
     6541 tccagcgaac aagccagatg ataagtgcga ttgggattag aactttgacc gcaaaccata
     6601 aaagcccgct taggacactg acaaaaagac tgatgacgaa gctagctgca attagcacta
     6661 aaagaaccat gaagatattt aagaacatat ttttttgacg catacaaaac cctcctcttg
     6721 ttcattcttt actatagaaa aagtataaca gggattgttt aaaaacacct ccaactgaag
     6781 actgattttt acttcatcta cttaaatgat caaacaattg ctttttctct ggtttatcat
     6841 ctaaaataga gcggaaaagg aggagaatat catgcctaaa aatcgtcttg aagcatttac
     6901 agatgctgta atcgcgatta tcatgactat tttagtttta gaacttcatg aacctaacgg
     6961 agacacgtgg gaggcgctcg ctgcattagg ttaccgattt tttatctata ttgtcagttt
     7021 tatcatttta gcgatttatt ggaacaatca tcatcattta tttcaagttg tacataagat
     7081 aaatggacgg gtcttatggg cgaacagttt ctttgttttt gcgctttcgc tttttccgtt
     7141 tgcaacttca tggatcagtg agtacatcaa tagcctggct ccagaaatga cttatggttt
     7201 tgttaccttg accgctaata ttgcgtatta tatcttggca aaagaacttg tcaaagcaaa
     7261 taaaggccac gagaaagcat tgaaggcgat gttgaataat tacaagaaat cgtatctatc
     7321 gattggtttg aatgtgttag gaattgtctt agggtattta gtagcgccag tagccgtgct
     7381 gatcgcaaac atcgtgattc tagctgcttg gatcatccca agtcgtacca tcgaatcaca
     7441 atatcggtaa aatgatccgt gtttaaaatt taagagaaaa atatagaaaa aataaataaa
     7501 cgatcaaata tccgagtgat actagtattc aaagagggat gcagatggat caaaaaagaa
     7561 ttcatgtagg actgattact agttttgtca cgatgcttat ttatttggat caaggtcatt
     7621 tgacttggac agtagttggt gtcgtaggat ttttgacatt attcacagca ataaaaaaat
     7681 aaacatcttt atgtaatctg atgttctatc tatttaagaa aagcatgttt acagcagtat
     7741 gattctgttg taaacgtgtt tttatttgtg gaaaatttaa tttttagaaa agtgtatcga
     7801 aaaatagata gttagttttt ccacagtgga taacttcgta agagataaaa ataaaaaatt
     7861 agtcaaagaa gggcgtatag atttcttttg ataggagata tacaacagaa atgaataaat
     7921 attaacgtgt tttcaaacag tataaaacgg tgtggttttt ggaataaaaa aataacatat
     7981 ctcattttac gcttttgtta ttttatactt aaaaaataac gacacagaaa ataccgtgtc
     8041 tcagatttct ctactacttc taaaaactac tgtttttttc ctttgaaatg ccttcaaaaa
     8101 gtaggatcag gcagaatata ctggcagaat caaggagaag ggagcctaaa taaggagaaa
     8161 aaccatagaa aatataaagt aattacttat aaaacaagct ttttatagaa aaataatata
     8221 cctgagtagg gtataaatta agacggaatt cctttctaga ttgagatatt gactaggaag
     8281 aatgttaaga ttttaagcct ttaagctaaa aaaaaaccct ttttgttaaa taaggggaat
     8341 atagcctgtc agtttcaaac tgcaagtcgt cctgctgcaa taatatagta gattagagat
     8401 gaaaatagat ttttttaaac caatgactga ataaaaagac cgtcatagat acacattgga
     8461 atgtgtctat tacggtcttt ttttacgaac gattttattg aagacggaca gttcgggtca
     8521 aaaataaaaa agctacgatc agaaataaga ataaaatgta tcccaaaata atggctagac
     8581 ggtctaactt atttgtcgat agatgtttgt ttagaagttg ataggcccat aaacctatca
     8641 gtcctcctgt tgtattagtt atcaaatcag tgatgtccgc tacgccaata ccgaatagga
     8701 attgaatcaa ttctgccaag aagcttacaa ggaaaataat ccctaatttt ttagaaaaag
     8761 aaagtctctt gaaattgaca ttcaaaagca ccccaaaagg aaaaaagaca atcaagttat
     8821 aagtggtctc acgtaatacc gtcgtatttt caaaagaaaa agtagaaaaa gggacgagat
     8881 tgacattgct gtaagaataa gtgagaaatt gtggaagatt aaatgatagc ttgaataaaa
     8941 tcaaccataa tagaaagaat aaataaatcc ctaataaaaa ttttgataca taccgcatag
     9001 acatctcctc catttaaaaa gtataccatc gaaaaccgct gaaaaatcat aaaaaagtat
     9061 gaagtttaag gaccaacgta gttatcgtac gaaaattaga agcttttttt tgttgggaat
     9121 ccggtttctt taacaaagct aagatagcga gttgcttgga aaagttgcta tcttttttct
     9181 gtcaaaacga ctcggaatgt tcgttttttg ttctaatttc tccaagttgt ttactttttg
     9241 atactaagtt tatgaaaaat caagaaatag ttgttatact aggtaatgct gacaaacggg
     9301 attggcattt catcttggtt cagctttttt tccaattact aggaaggagg gatagattgt
     9361 tcaagactta ttttcgtttc aataaaatac aagataatcc ttttcgtatc atgaatctga
     9421 tgctacttat ctttattgta ttatggttag gttacataaa tcatgatttt ttgatttcaa
     9481 gtttttcatc attagggatc tttacttttt tctattatca aaacataccg atgaaatatt
     9541 tgctgaaacg tatgtttctg atcggttgcg gactgttggt tgctttcgtt ttggggatct
     9601 tatcgactta tgttttatgg cttgaaccat ttgccgtagc tttggttgct ttttccagca
     9661 gattcgtgtt gcgattattc catatttcta aaccaggtgg cttgtttttt gcgatgcttt
     9721 ctgccatggg aacgagcatg cagctgccaa tcgctcaatt accgatcgtc tcactttatt
     9781 tttttatggg tgtcgttttt gccctgattg cggcagtgat tacaaaatta ctggattcac
     9841 ggcctgagca gacaattgaa aaagcaactt taaaagaaag atttcacgaa gagcctttag
     9901 tgatcattga ttctgttttc tacagcgctg ccttatttct ttccgtttat gtcagtcacg
     9961 gcttgaatct gcataatcct tattggttga ccttgtcatg tgcatcgatt ttgctagcag
    10021 aaaacttgga tgcgatgaag catcgacaag tccaatatct gattggatcg atgggtgggt
    10081 tatgtgtgtc ggcattcttg tcatttgtgc cgtttacgca gttgcagacc atttttctga
    10141 tcacttttct atatggaatc gcacaatttc tagttgctag aaattatgca gttgctaata
    10201 tttttcttaa tccgatggcg ttgatgctat ctacacttat tcgtggagca tacttgattt
    10261 ctttgatcga atatcgtttt ttagggatcg tcataggaag tttcatcggt ttaggtgttg
    10321 cgtgggtaat gacggttggt ttgcaacatt atttaacggt tgttcgtcaa aaattagaat
    10381 agaaggacaa atatatgtgc caaaagaggt tatgacaaga tttttgtcac aacctctaat
    10441 tcaaggtgtt caaaagccag attctcagca ttaagtcaaa ttcacacaaa aatgtggaaa
    10501 ggaactttca aaaaaatttt atatttattc tatcaaaaaa ttttatattt attctatcaa
    10561 aaaattttgt ttatgatggt aactgaataa actttcctga gatggtcaat gctttccttg
    10621 aaagtcttac agatattctt tcttcataga aagtttaagt tttatagtta gtgtacaata
    10681 aaagtatgtt tataccatat ggtgtccgga taatcagtca tttaaacaat gaggttcaaa
    10741 gatatgaaaa ggggaaattt gatgaagaaa ataagcaatg aaatccaaat tctggcagaa
    10801 actttaactc ttcccaaagt cgttatagag caaatgattg tacaagcaaa aaacatcctt
    10861 gatgaggtgt ttgagcaata tagtcatgaa ctaatggatc ctaataaagc aaaggcgact
    10921 gcaaagaaaa tagacaaagt ctatgaagag gaaccttttg cagcattagc tatttatcta
    10981 tatgcagctt ctcaaagttg gaaaaaaatt tatcaaccat tgaagattcc aagaactatc
    11041 tatttggcaa caatgaatgc ttttactaga tttattcatg aacatttcca agtaacagga
    11101 agctatcgct ttgaccgtgg tttttggatt tggcattaca ctagtggctt gatctttcgg
    11161 attggtgaat tggagtacga aatgacatat tttccgaaag ggtacacgga tctaagatta
    11221 gaaggaaagc agtgcctttc tcttcatatt ccttccgatg cagatttatc tcagaataag
    11281 ataagagata gttacgaaag tgccattcgt ttttttgaac tttattttcc tgattaccat
    11341 taccaagtga tgtacacaga tacttggtta ctatcaccca atcttactaa atggttgaaa
    11401 aaagagtcaa aaatctgtct ttttgcagcc gattatcgat tattatcagt tgatgaacag
    11461 gacgatagtg gagtcccttg gatctttgga cgagtagatg cccaaataca tgattatcca
    11521 gaaagtacga gtttacagcg acaagcaaaa gagcaattgc ttgcaggcga gcacattggc
    11581 tctggcttag gtattcttac ttcataagtt tagtacttcg aaatagttta aaagagcgtg
    11641 agacaaaagt aaagaacact tttgtctcac gctctaaaca cgtataaacg gcggaagcag
    11701 aagcaactcc ttcggaaata agctgaaatt cacaaaaatt tgaaaagcaa ttttcgtgaa
    11761 tttcttctta tttcttggag ttaaacgctt ctgtcccagc ctctttttta gtgttctatc
    11821 gaacacacag tacgttcaat aggtaaacta gctataacaa tagatattaa agttaacgga
    11881 caagagggcc ttttttaggt agctaaaacg taataatgaa aatttatttc cagagatagg
    11941 agtcaatcag ctagtctgat cgactgtttt aacaagttga ctttcatttt aacttttgat
    12001 accatttaaa acacaaatcg taattgtttc gatttgtgtt ttttagcatg actacaatca
    12061 aagaagaaag tgggtcgtcc atatggaaaa aacagatatc tcaagtgcat accgccgctt
    12121 gaaaagccca aatatcaaaa cacgaaaacg tgcgctgaag atcatcaaag atgtgaaacg
    12181 gaatagtggg aaaaggtaag aagaaggaaa cttaattaaa aaaatagccg aaaaacgttt
    12241 ttcggctatt ttcaataatc ggtttttgtg taaggtttcc gaaagaactg ctgttgattt
    12301 tccattttta acatatgata aattggtaga atctttcttt tcaaattgat accattccct
    12361 aattccagtt atatagttaa ctacagaacc acaaagcacg tacgtttata aaagtattat
    12421 ctgtagttat ttttcaattc cctttcaacc tcttattttg accagtagta ttgatcactt
    12481 taccttttaa cacctttgtt cgtttttgaa acatttttag tcaagaatgg aaacgtaact
    12541 acataatcaa aggttttgcg aaatatttca tgaaatattt catgtagaag cgagcaatac
    12601 ggttgcaaat aaccattatc gtttaataag cagttacgaa agctcccaat atctctaacg
    12661 ttcagctcac tccatttctt ttcttcaaaa aaatcagtga ttcgtatctc tttctatttg
    12721 tcgaaaaagt taactttaaa aagtaacgcc gaaaaaatat gcaaaaaaat aaaaaagcag
    12781 ttactattgc tagaataaca tcaaggaata ataagttttg gttttcagat aatagtcgat
    12841 aagttgtgta ttggaatttt agatacagta ataaagtatt tttcatgaaa ttttgtgaga
    12901 atcactatta caagtatctt taataaaatt aatggttaag gaggaactta aagtagaatg
    12961 taaatgaata gttgtagtca gtcgattgtg atactagact caaagttgca ggaataagtt
    13021 tttcaatttg tgattggaag ataaaaaatg aaaaagaagg gctttttttt atactttgtt
    13081 gattgtagtg tttattttcc ctctgtttag ccaagtaaca ttttctatga ctcaaccagt
    13141 ttcaagtgag gaacatgata acctttttcg tgctacagaa gagtttaaga aatatcagga
    13201 aaatattgtt ccggagactc cattagctag tgagccaatt actgatattg atggaaacca
    13261 aataggatgg tatatacagt acgaagttat ggtggtaaat aatgactcaa tagtaaaaaa
    13321 tacagtaggc ttagagctaa caccgattga aaaggtgagt tcattgttaa cgtatattta
    13381 tactgatgaa agtgacgaga ctgagatcat tttaacggat tactcaaaaa ttgctactga
    13441 taaaaagtat atattgtgga tgtagacact agtgaaatac tttatgatat agaaattgat
    13501 gaaaatttac tagatgtagc acaagaaatc gatcatcaaa agcaggaagc tattcgatat
    13561 gctggtagaa aagggaaaag aaaatattta ttacgtgaat gtagcaaaag ttagagaaga
    13621 tgaaaatgag tggaaagaat tcaagagtcg ctactcaatt aactcgactc cgacatttac
    13681 agtttacaga gaaggatcga tagaaaaaac tgttttttgg actaaagaaa gtggaatgtc
    13741 tttagctgaa gtagaagagt ttttggatta tgttagtatg caacagtaag ggagttctta
    13801 ttatgaaaaa ttttgacaca tattatgtta ttgttttttc gatatctttg ctgttaatat
    13861 tactaacttt aatgcagtat aaagagtatc cagagtattt tattttaact tttgtatatt
    13921 tagtaagtag ctacacactt ctatataaat tcagaagttc ttctagagtt tctaaagttt
    13981 gtttcttaat tagcttattg attctataat atttttgatt tatataggaa attaaaaata
    14041 ttatagaatc aacactcaga gaacgggttg gtttttaata gatttaataa gtactgataa
    14101 tgaaatttct cctggttggg aaaacgaagt tggttaccct gtagaagaat tttttcaaga
    14161 ttactttgcg gagtatgccg ataggataat gagagattac gtaacagata aaactcaaga
    14221 agtcatcaat caatcccagt cattaaatga attatctgat aaggcgaaag aagaagcagt
    14281 tgccattatt tcttcaggga ttagtgacta tattgatatg agtggtgaaa tcaattatgg
    14341 cgataaagac aaaattgtac gcatgataaa agcttttatc aaaacttttg atgtgaaggc
    14401 agatcttaag tttaatgata cttacctagt aggaaaatta attaatatcc ttgggacaga
    14461 gaaagatacg gaaacgttta tttcctcttt gtctatgttg tttacagata agcatttttc
    14521 aactcagctt ggtggagagg aactagtgga aatcttttaa ccattacgcc cagcattaat
    14581 aaaagtatat caaaaaagta ctcctgatga tttttaagat tggtttgaga aataatgtga
    14641 aaacactatt tttaatgtta attatagata gagatgaacg cgtcatatgg ttaaaagaat
    14701 gaaaaagtca aagatacact gctatatttc actaaggata tagcagtgta tctttcatgt
    14761 cgtttcactg gcagtttttt ataaaaggag gtgtgcattt cagttgcttt tctttggtag
    14821 ttagttgaat cgtttaagaa ttaacggatg tggcagacag gtgctctgtc caaaaaccag
    14881 taaaatcttt gatggttcca tctttattta gctgtgcctg ttcaaatact gttttgtttt
    14941 taccgaatgg atcaattgca ataattgttc cgatccccgc acgtttggca gcaagtaatc
    15001 ctgagtaagc atcttcgata acaagacaat cagccggagc taagctcagt ttgtctgccg
    15061 ctttaagaaa aatatccggt tgcggtttcc cagggaaaga gccgtcgtca tagacaatct
    15121 tgtcccagtc aaaccagcgg gctaaatcga aaatatcaaa ataaaaagca acattctctt
    15181 tgacagtagc cgtggcaatc gttaatggaa tctgttggtc agtcagctgg tcaagagtcg
    15241 cttcaagccc ttttgtcaac tgaagctcgt tttcattttg caagcaaagc atacgataat
    15301 agctttcttt ttcttctgac aatacggcga tctcagaggc ggtcaaatgc tctgaaatga
    15361 aatgtttcaa aatctccgta ttcgtccgac catgaatatt ttttaaaata tcctcgtctg
    15421 ataaaccatc ttttgtatga tcatgtatca tatgcagcca agcagcttca tgcagatgag
    15481 agtccaaaaa cattgttccg ttgaaatcaa atataatccc tttcatagtt acgctcctat
    15541 agtggtattt tcggttgaat cagcaatttg cagatcgaca tattgtgcat agtgctcttg
    15601 aacctcccgc gagatctggc gatccgtaat gagcagatcg aaatcatgca aattataaaa
    15661 cacataaaaa tcatctcgat tgaatttttt attatcaacg agtagatatt tcttacggga
    15721 attatttaga gcgatctgct gtgcttctcc ttcttcggta ctgtaagtag agatcgcttc
    15781 gttgtgaacg ccatttgaac tgataaatgc ttttgtaaac tttagtcttc ttaaattgtc
    15841 gttggtgatc ggtccgacaa atgcgccggt atttttccgg aaatcaccgc caatcagtag
    15901 aatttctggt ccatctgctt gagcaagaat atcaaaaact ggataattat ttgtaatgat
    15961 ccgaattttc ttgttcagta aatgcgtcgc caatagttcg attgttgtac ctggtcctaa
    16021 gaaaatcgtt tctccctcgt gaatcaagga ggctgctgtg gcagcaattt cttttttttc
    16081 ttgaatctgc agagtggctt tttcagtgtg agaaagttct tgatctaaag tgtaggaaag
    16141 actttgagcc cctccatgga cacgcagcag cttgcccgat ttttctaatt catctaaatc
    16201 tctgcgaacg gtcatatcag aaacatctaa ttgattgatg atttcattaa cggtaaggat
    16261 tcctttttta ttgaccattt ctacgatagt aagcaatctt tcttttttca acattgtctt
    16321 cacctctaat ttaaggataa tctatcatat aaacggacaa cagtcaatct aattcgaaca
    16381 aaagtaaaca tttagggtgg tttttatgtt tgttacaata gattttattg ctgttttctg
    16441 gtttttatga ttatttgtgt ttgtttttgt tgacaaatgt tttggatgcg tttacaatgc
    16501 aatcagttag aaagagcgaa aactgattat agatttgagg agagatgtac atgcttaaat
    16561 taccagaaga ttttattttt ggcggagcca cagcagccta tcaggttgaa ggagccacta
    16621 aggaaggtgg caaaggcgct gttgcttggg atgacttttt agaggaacaa gggcgattca
    16681 gtcccgatcc ggcaagtgat ttttatcatc aatatgcaaa ggacattgaa ttgtgtgaac
    16741 gttttggtgt aaatggtcta agattatcca ttgcttggag ccgcattttt cctgatggag
    16801 ctgggaaacc aaatccagaa ggaatcgctt tttatcatcg tgtgttcgaa gaatgtaaga
    16861 aaagaaacgt aacgccgttt gtgacgttgc atcattttga tacccctaaa cgtttgtttg
    16921 accatggaga ttttttgaat cgagaaacaa tagaagcatt tgtttcctat gccatttttt
    16981 gttttcatga attcaaagaa gtcaaggtgt ggagtacctt taatgaaatc tatccagttg
    17041 caaccaatca atatttgtta ggtgttttcc caccaggaat caaatatgat tttacaaaga
    17101 tcgtcgcctg tcttcataat atgatggttg ctcatgcccg tgtagtgaac tatttcaaag
    17161 aaaacgaact tccgggtgaa attggtgtag ttcactcatt agagacgaaa tatgcggcaa
    17221 cagacgcgcc ggaagataag catgctgcct ttttagacga tgcattgtcg atccgtttct
    17281 tattagatgc tacctattta ggctattatt caactgaaac cttgactgct cttgatgaga
    17341 tatgtgaagc aaatcaggcc agctatcatt ttcctgaaga agatttcgtt gaattgaaaa
    17401 aagcatccac gcgtaatgac tacttaggga tcaatcacta ccaatgccat tttgtcaaag
    17461 cttacgatgg agaaaatgca atccatcata acggtacggg tgaaaaaggg acctctgttt
    17521 ataaagtgaa gggaatcgga gaacgtattt ataaagaagg aattcctcga actgattggg
    17581 actggctgat ttatccagaa ggtctatatg acttgttgct gcgaattaaa agcgattacc
    17641 cacattacaa caaaatctat atcactgaga acgggatggg gtataaagat cagtttgaag
    17701 atggcattat tatggatcag ccgagaatcg actatttgag agtctatttg gaatccttaa
    17761 gcaaggcgat aacagccggg gtaaatgtga aggggtattt tttgtggtcg cttatggatc
    17821 ttttctcatg gacaaatggg tataacaaaa ggtatggctt gttttatgtt gattttgaaa
    17881 cccagaagcg ttacccaaaa gaatcagctt actggtacaa gttggtcagt gaaaccaaaa
    17941 cgattattta ataagtgata atggaggaag aaaagatgaa taaagaggaa ttacaaatgc
    18001 ttggttttga gatcgttgca tattcaggcg acgctcgcag tacattattg aaattattga
    18061 aagaagtaag acaaggaaac tttgaacatg ttgattcggc gttgaaagaa gccgacgaaa
    18121 atttaaccct tgcacataat tcgcaaacaa aaattttagc ggaagaagca tctgggaaag
    18181 agatggagat gggattcatt tttatccatg ggcaggatca tttaatgacc actttattgc
    18241 tgagagatct gattcaagac tttattgtac tgtacagaca gaatcaagga taggagaaga
    18301 acgctatgga tggaatcatt aaacaaatcg aaaaagggaa accatttttt gaaaaaatct
    18361 cacgtaatag ttatttagga gccgttcgtg acggattttt aacagcgatg ccagctattt
    18421 tattttcaag cattttcatt ttgattgctg cggttcctga gatttttggt taccaatggc
    18481 ctgaatctgt ctccacatgg ctatggaaag tctataatta ttcgatgggt gttgtagggt
    18541 tactcgtttc agcaaccact gctcgctgct tggctgattc gatgaatcgt cgcttaccga
    18601 aaaacaaagt aatcaacacc acctctgtga tgctggcctc tgtggtaagt ttcctgttgt
    18661 taagcgtctc tccgattgaa ggtggatttt caacggaata tatggggaca aagggactac
    18721 tggcttcctt tgtcgctgca tttttaacag ttaatttata taagttttgt gtgctgaaag
    18781 atattaccat taaaatgcct aaagaagttc ctggaacgat ttcgcaaacc ttccgagata
    18841 tttttccttt ctctttttca gtatttgcgg ccgttttaat tgatttaggc attcgacaaa
    18901 tcttccaaat ctcatttgca gaagcaatca ttacggtgct gcagccgcta tttacagcag
    18961 ctgacgggta cttaggaatc gctattatct ggggagcgat ggcgctgttt tggtttgtcg
    19021 gtgttcatgg accgtcgatc gtggagccgg caattgcggc aattatctat gccaatgtgg
    19081 aaaccaatct gcaattgttc aattccggtg aacaagcttc taaagtactg acggtgggtt
    19141 tagggaattt tgtaggaact atgggaggaa ctggggcaac attggttgtt ccttttatct
    19201 tcctactctt tgctaagtct aagcagttga aggcagttgg gaaagcttcc tttattccag
    19261 taagtttcgc tgtcaacgaa ccattgctat ttgcggcacc catgattttg aacccttatt
    19321 tttttattcc atttttgtta acacctgttg taaacgtttg cctgttcaag ttttttgtcg
    19381 atgtattggg catgaacagc tttatgtacg ttttgccttg ggcaactcca gcaccgatcg
    19441 gtttggttct aggaacgggc atgggtatct tagcttttgt tctagcagcg gttctaatcg
    19501 tcgttgactt cctgatctat ctaccatttt gcaaagcata cgatgctgtc ttagtagaga
    19561 aagaagcaca aaaagcagag gtgatcgcaa ccgaggaagg tgcttctgcc gatgtacgtg
    19621 aggaagtacc tgtggcagcg agtcaagtta tcagcgatgc aaataaagaa atcaatgtgt
    19681 tggtactttg tgctggcgca gggacaagtg cgatgttagc taatgcttta aaaaaaggtg
    19741 catctgaatc gaaagcaccg atcagtgcaa tggcgggtgc ttatggttct cattacgaaa
    19801 tgctgcagga ttttgatatg gtggtcttag caccgcaagt caattcttac tatgatgata
    19861 tcaaagaaga caccgatcgc ttaggaatca agctggttgc gacaaaagga gcagaatata
    19921 tcggattaac gagagatcct gaaaaagctg ttcagtttat tctgaaccaa tttcaataaa
    19981 ggaggagcca taatgaaaat gggaatttgg ttgcgtaaag ctgttttatt tgcagctgtg
    20041 ttaggggctt tgggggctgt ttcaaaaact gttgaagcat ctgccagcga atttattcgc
    20101 ggagcagata tttcgatcct gtcagatatg gaaaaatctg gtgcaaaata ttatgaagac
    20161 gatatttcaa aagatgcctt agagatttta aaaaataatg gtgtcaacta tgttcgactg
    20221 cgtttgtggc aggatcctta taatagtaat ggagaaagtt atggagcagg gacaaatgat
    20281 ctggaaacga cgattgacct tgcaaaacga gcaaaaaatc tgggacttaa ggtgctgctg
    20341 gattttcact acagtgattt ttgggttgat cctgggaaac agaatcttcc taaagcatgg
    20401 caaggtctga cctttgaaga aatgaatacg gcattgtacg actatacaaa gaacgttctg
    20461 tcggaaatga agcagctgga cgtttatcct gatatggttc agatcggcaa tgaactgaat
    20521 agcggaatgc tctggcctta tggcaagtct tggggagaag gcgggggaga atttgatcga
    20581 ttggctgctt ttttgaagtc tggtatccaa gctgttcgag acactcaacc taaaacaact
    20641 ccagtaatgc tccacttagc tgatggtggc gatacaggag catttacttg gtggtttgat
    20701 gaaatcacga gtcgaggtgt gtcatttgat ttaattggag tgtcgtatta tccgtattgg
    20761 cacggttcaa tgaatgaact tcaaaccaat atgaatgcga tcagccaacg gtatggtaaa
    20821 gaagtgatcg tagttgaaac agcttatggg catacaacag cgaatgccga tactatgcca
    20881 aatgcttttg gtgaagccga agcagctgcg gggggatatg aaccaacacc gacaggacaa
    20941 gcagagtatt tgctggatct tgccgatcgg attcaggcag taccgaataa tcgcggggcg
    21001 ggcttcttct attgggaacc tctttggtac aacggaaatg tgagttgggc aacacaagca
    21061 ggtatgaatt atctcagtgt tcaatccact atgggaaacg aatgggacaa ccaagcgatg
    21121 tttgattttg ctggaaacgc cttgccaagc ttgcgtgcgt ttaaacaagc aggggcgcaa
    21181 ataaatctag ttaaaaatgc aagtttcgaa agcgatggac caacgaccag tccttccaat
    21241 tggcaaacct ggtttcaaca aggaaccgct aagggtacga tcaaaacgga agcgggcact
    21301 ttttttgggg actacaaact aactttttgg caggatcaag catacgaggc atcagcttat
    21361 caaaatgtta gtggcataag caaaggaact tacacattga gtgcctatgt aatgtctggg
    21421 ggagagtttg atactaatca gttatatatc aaaaattatg gtggagcgga actaaatact
    21481 gcggttgtta aaacaagtga atggacaaaa attacaatca aagacattcc aattacaaca
    21541 ggtgtttgtg aaattggggt ttatagcaag gcttcaggaa atgcttggac gaacgttgat
    21601 tttgtttcat tggtgaaaca atagactgcg gatcgtttcg attcaagatc ggaggttccc
    21661 ttcagccaca tcgttagcgt agaaggcagg aatcgaacct gcacctcgcc tttgccaaaa
    21721 ataaccagaa acgatttcca gtcattttta ccaaaacgag taaagcacca gacttcatct
    21781 acactttgta ttatgctaaa gagagttcaa cgatttcgta agaagcaatg aaaaaattgc
    21841 aaaaagttgt gcagataaca taaagtttgt ttaagaaagg gtaaccttag aattccgtcg
    21901 tgaatatgat ttgagcactt agatggatag aaaaaagttc tcggaaaaca gttcgttttt
    21961 cgagaacttc tttttatgat aagaatgaaa caaattaact tatattatag tctcttttgg
    22021 tagggaacca tcttattttt aatgaaaatc aagcatttta gctattgaag aatgttgatt
    22081 tatagggatt ccccctccat attatgttgg ctctttattc ccactctgtt ttcaacgtaa
    22141 agtgtataaa acagaatgcg atactatcaa gggagttaaa acaatataca gaacagtaaa
    22201 acactataaa taaaaataaa agtgcaataa aagtgcaatt tttgcaccta atcatactct
    22261 gtttatatat gaaaactaga ttctgaatcc aatatttggt taacgagagg cgttcgaatt
    22321 tgaacgtctt ttatatatta ctttcaaata aatatgaggt agaatactat ctattttctt
    22381 tttaacccaa ttgttataat ggagagtgta aaatattttg tgtaaataga aaaaaggaag
    22441 tcccttctgt agaatagagt taccacaaca cattcacaga agagaggact tccctatgaa
    22501 cgattttact acagaaattc taaagactct agcgaacaaa ggcgatttga atgaattatt
    22561 ccgtgtccat ttggagaaag cagtcaatac gcttctcaaa acggagttaa cggctttcct
    22621 agattacgaa aagtatgatc gcattggttt taacacgggt aattctcgta acggctccta
    22681 tgaccgtacg gtcaagaccg agtatgggga acttcatctc cagattccgc gcgaccgcaa
    22741 tggtgagttc aagcaacaga ctgttcctgc ttatagacgg acgaatgaca cgttagagga
    22801 gaccgtcatt cacctcttcc gaaaaggtat taccatgtcg gaaatcgcag acttgattga
    22861 gaaaatgtat gggcattact acacgcccca aaccatgtcc aatataacaa aatcatttac
    22921 agaagaggta acggcgttta atgggcggga gcttcatgac cgttatgctg ctatttatat
    22981 ggacgcaacg tatattccgt taaagcggaa aaccgtcgcc aaggaagcta ttcatatcgc
    23041 agttggcatt cgcccggacg gatcaaagga agtattgagc tatgcgattg caccgactga
    23101 atccatcacg atttgggagg aaattttatt ggaccttcaa gagcgcggtt tgaaaaatgt
    23161 cctcctgttc atcacggatg gcttaaaggg gatggtagga gcgattagtc ggttctatcc
    23221 caaagctcgt tttcaacatt gttgtgtaca cgtttcccgt aatatcagtc ataaagtgcg
    23281 tgtcgatgat cgtaaggaag tctgtgatga ttttaaaatg gtgtatcaag cctcatctaa
    23341 agaggtggcg ttggaagcac gtggtacttt tgcggaaaaa tggaaaacca gctatccaaa
    23401 agtggttgaa tcgattcttt cgaacgatca cttgctcact ttctatgatt tccccttggc
    23461 catacgcaag agtatttatt ctacgaactt gattgaatcc tttaataaac aaatcaagaa
    23521 atacagccac cgcaaggaac agttccaaaa tgaagagtcg atggaacgtt tcttagtctc
    23581 gtcttttgat acttacaacc aaaaattcct aggtcgcagt cataaaggtt tccaacaggc
    23641 cgaaggcgag ctcgaacaaa tgctaagcca actgattgag aattagaaac aatctgcagt
    23701 agggaagaat catttacaca aaattattga cgctccctta taatgagaac ttttactaac
    23761 ataatttatg ataaacttac tatataatca tattaattaa atagttagga gatctgctta
    23821 tgtttatatc tactcttcaa attcgaaatt ttagaaatta tgaatccgaa atctttcgat
    23881 tcgataatga gacaaatact attataggtg agaatgattc agggaaaacc aatgctctta
    23941 ctgcattgag aatcttatta gatgatagtt attactatag tagtaaaaca ctaaaagaat
    24001 cagatttttt tcatggaatt caaaatgggt ggcaagggca ttggattatt atctctgcga
    24061 catttgaagg aatcagcgaa gaagaatttg acaatgagat ttgtgcttcc atttctttaa
    24121 attctgaaag tcaaacaatc ttagaagaat tgatttcaaa tgcagataaa ggtgtaggta
    24181 gtatttctct atttattaga cctaacaaag ctattagaaa gcaattattt gatatttcca
    24241 ctgaattaga ctctcatcaa tttaacgaat ttagaaattc tattcgtcta tccgactatg
    24301 aattttacta cacatctaaa tcaaatctaa atttctgtat caatgaaaat tatgataaat
    24361 tggtaggaag actcaatgac aatatagcta gtaatcctga agaagacgat gaagctctgt
    24421 tgggctcaag aattgacatg tcagatattt tcaagcatat ttcggttgtt tatgttgacg
    24481 ctcttcgaga tgttcttaga gaaatgaaaa acaatcgaaa cccagtcaaa agaatcatgg
    24541 aaacaattga atcaaaaata tcatcagata atgttgagtc attaaaaaca attatacagc
    24601 aattaaatga gactattacc agtgttcctg aaattaggaa aattggcgaa aatattaatc
    24661 ggcaactaaa tagcataatt ggttcagtgt attctcctaa tcttcttctt tcctcaacta
    24721 tgtcagatga tatgggttct ttagcaaaat ttctttcaat gaagccagaa caaaatatcg
    24781 acttagactt actagggtta ggacatctaa atatgattta tttagctttg aaaatagtcg
    24841 aatttgaagc gtgtcgttca agagaactac ttaatattat gttgattgaa gaaccagaag
    24901 ctcatattca tcatcatatt caaaaaactc tgttcgaagg attaaatctt caaaaaaact
    24961 atactcagat tctcatgacc acacattctg tacatttagc tgaagtgtct gaaatatctc
    25021 ggatgaatgt attaaaatcg tttaatggca aatctatcgt tatgaatcca gcaaataatc
    25081 tgaactcatt tgctaaagaa aagttaaaaa agaacaatct aaatctaata aacgcagtag
    25141 agagatattt agatgttaaa agaaatggat tgcttttttc taaaggtgtt atcttagttg
    25201 aaggagatgc tgaagaaata cttattcctc aaatagtaaa aaaattattt ggtataaact
    25261 tagacgaact tggaataggt ttgattaatg ttggtagtac ttcgtttgaa tatatcgcta
    25321 gcttgtttga cgatgataga atacagagaa agtgtgctat tgtaactgat ttagatgaac
    25381 aggcaatccc atcagaacat cgattgtata aaagcactgc acaagagaaa ggtcaagcaa
    25441 gaaaagaaaa attatcctcc ctttttaatg aaaacaattg ggttaattgt ttttatgcta
    25501 atacaacatt tgaaattgag tttttagatg tgaataaaga aaatattcta acttatgtca
    25561 gtccaattat agatgacgca ttcaaagata aaaaaacaat aactgcttat aaagaagaaa
    25621 tacaaagtga acaatattta gaaagaaatt tagcgatgtt aaaactagcc aatcatgttg
    25681 gtaaggggtg gtttgcaatt gagttaggtg aaaaaattga ctttttaatc aaaattccta
    25741 agtatattct taatgctatt gcttttgcat gtcaggaaat agtagatctc tcaatttata
    25801 aaaaaattct actccataca atcgacttgt acgaggaaac tacagaattg tcagctttat
    25861 cagctagttt aaaaacaagt gatacagctg atttgaatat agcaataatt tctttattag
    25921 agtactttgg taaagatgag gatgttgtgt atctaatcaa tcagatagaa aattacacaa
    25981 aaatacttta tgctgaggtt tcaaaatgac aaatatcttc gaaaaaatcg taaatgattt
    26041 aaatttagaa caaaaagatg ttgtggaaag tgaagataac ctttatgtaa atgcatgtcc
    26101 tgggagtggg aaaacaaggg tacttacaag gaaaattgct taccaagcaa ttaaacacga
    26161 tggatcacta aaaagaataa ttgctatcac atacactaat agagctgctg aagaaattaa
    26221 ggaacgccta agtttactta gtatagatga tgatattaat atttgggtgg ggacaataca
    26281 tcagttttgt cttgaattta ttatttatcc ttttaaaatg aatctctcaa gagtatcaaa
    26341 aggatttaca attattgatg attatactca aagagcttac gtcagccaaa ttaataatat
    26401 gctgaattta aatctcaaaa cgtatgaact gaacaaaatt gatttgtcac tttctcatga
    26461 ttttaaaatt aatgaagttc agtatactca agtttctgaa atgtatcaca ctatgttgga
    26521 aaaaaataaa gaaattgatt ttgatatgat tttactagta gcgtataaaa ttttaactgt
    26581 aaacagtaac gttgcacgta atattgctag taatataagg gcgatttatg tggatgaatt
    26641 tcaagatact agagaattac aatacaatgt aatagctaaa ttacttcaaa acaaccctca
    26701 aattcagtca atgtttgttg gagatattga ccaagcaatt tatggatcat tagatggtat
    26761 agctaaatca gttgaagaac tagaaatgct aactagtcac acttttcaat caaagacgct
    26821 acatggctgt tacaggtcta atcagagatt agtagacttc tactctaatt ttcagagttg
    26881 tccttacgag attgaaagca gagggaataa taaaaacgac cgtggtttta taagttatga
    26941 ttgcaaagtt actaaggagg atttacccaa cataataaaa aatataataa aggaaaagat
    27001 tgaaagcggc attcatgaaa aagatatttg tgtacttgct cctcaacact atcctctgtt
    27061 ttcactgggt gagtatttaa agaaagaatt accgtattgc aattttgatg ctataaatat
    27121 atcaccaatt aaggtaaata atcatagttt atttttcaag ttagcaattt tgtactttac
    27181 tgaatcaggt gaaaaggttc gaagaagaaa gctaattgca aacgatattt taattatatt
    27241 aaaaaatgaa tttggaatag aagttaaaga ttattttatt gacttagatt tattacagct
    27301 aataaacagt gtgaaaagaa tgtatagtgg agacgacaac ggtgttgatt tatacaaatt
    27361 tgttaccaaa catatatttg ttaatcttaa tattgacgag aaaaattacc cgtctatttt
    27421 taagcactat ctatttttta ttaacgaagt agaagatcgg ataaaaaata attcattatc
    27481 tagtagtgta tctagtttta agaagatgtt taaatctcga gatggtatca cacttactac
    27541 agcacataaa gttaaaggaa atgagtatga tactgttatc gctattaatc ttctaaacgg
    27601 gaaaattcct cattggaatg aaatttttaa tgtttctgat aaaggaatta gttcagcgag
    27661 aaaactacta tacgtaattt gttcaagagc aaaaaataat ttatttcttt tctcagaggt
    27721 gggttatttt acgagtaaag gagacttgct ttatcccact caattattag ataaaataga
    27781 atttgattat aatatttaaa atacctaggt agtcgttgtt ttaaatatag taggaatcgg
    27841 acgctcagta cggagcgtct atttttttac ccaattttga aaggaagtga acttatgaaa
    27901 ataaaaaatc aagaatcaaa aggtcgctct ccccccttta aaaccatcac acaaataaga
    27961 ttcattcaaa cataaaaaca gaaaggatag gtaaaaatat ggaacttaaa tatgtcattc
    28021 ccaatatgga aaaaacattt ggacaattag aatatgctgg tgaagggaac attgaacaac
    28081 gtcgaataaa tggcagacca accattctct ctcgtagtta caatttatac tcaacgattc
    28141 aacgagcaga tgatattgtt gtcattcttc cctccgaagc tggcgagaaa cattttgaat
    28201 ccgacgaaaa agtcaaactc atcaacccac atattaccgc agaaggttat aaaattggca
    28261 atcgaggatt taccaattac attatgcacg cagacgatat ggtgaaagca taagaaagga
    28321 aaggtgaaaa aatatgagat tagcagaagg tattgtgatt gaaaaagacc agacatttgg
    28381 cacattgaaa ttttccgcct tgcgtcgtga ggttcgtatc cagaatgaag atggtacggt
    28441 ttccgaagaa attaaagaac gtacctatga cttaaaatca aaaggacaag gacgcatgat
    28501 acaagtcagt atccccgctt ctgttccttt gaaagaattt gactacaacg cagaagtgga
    28561 attaatcaat cctgtggcag ataccgtagc gacggctact tttcgagggg cagacgttga
    28621 ttggtacgtg aaagcagacg atcttgtatt aaaaggacag acaaaacctc atcagaaata
    28681 taaaaaagaa gcgtccgaaa gtgaaaaata ggtgttgctt atgacaaaca caccattgat
    28741 tttgaaagaa attccgaagg atgaagccat ttcttttatt cggcaatacc attattcaaa
    28801 gatactccct agattgtgta aatactttct agggattttt tcagaagaaa aattattagg
    28861 cgttgtggaa ttaggctggg gtacgcaacc cctacaaacc atacgcaaac tctttcccga
    28921 cagttccctt caaaccacag attatttaga aattggaaag atgtgttttc ttccagaaat
    28981 gaatcaaacc aattattttg gcagtcaagc tctttcagct ctaattaagt ggttgaaaga
    29041 acatacggac tgtcattttt tatatacact ggcagatgga attgagggaa aatgtggcta
    29101 tgtctatcaa gcgtccaact tcttttactg cgggtatttc aagacaagtg tctatcgtga
    29161 taagcagtca tgggaaaaga tacaccctcg aagtgctcgc cttttattag aggaaaatgc
    29221 tcgctttgaa caggtagaga aaaagcattg gctttcccag gcattttgcg aatacaaagg
    29281 gattgagaaa atcaatggac gcatgtttcg ctatctctat ccgttgacaa aagaagcgaa
    29341 aaaactgtta ggacacactc tctatcgacg tcattattat ccgaaagaaa aaaatttacg
    29401 ctttgaaaag cgaatcgctt atcagaaata tgaagccatt tctcaaccaa cttttgataa
    29461 acaggctcgt atctacaata cacaattatt ttgataggtg gaaaggagga tttttatgcc
    29521 attgcttcat gacagaggag agcgaatcaa agccaacgat aagcacttgg tctatcattt
    29581 tgtactaatt tcattgctgg tagtttttct agtcgtccta ctcccttttc attggagagc
    29641 gttacaatcg gtgaactggc aagcagttca gttagataca tttttctatc aacttcatac
    29701 gccatacttt tggagcagta ttctcactgc tctttttgta tgcggactta tcagctggct
    29761 ttattatcac tatcgtatag attctataaa acagttagag caccgtcaaa agttagctcg
    29821 tatgatttta gaaaatcatt ggtatgaagc cgaagaaact caatcagagg gattctttaa
    29881 agatttaccc agcaagaaaa ccaaacaacg aatccgccat tttcctaaaa tatattatcg
    29941 aatgaaagat ggactaatcc atattcatgt agaaatcacc ttagggaaat atcaagatca
    30001 gcttttgcac ctagaaaaca aactagaaac aggattgtat tgtgaattag tggaaaaaac
    30061 gttgaaagat tcttatgtag agtatgtcct actttatgat actattggca atcgaattgg
    30121 cattgaagac gtggtagctc aagatggacg tgtcaaattg atggaatcgg tctattggga
    30181 gttcgattct ctccctcaca tgttaattgc tgggggcact ggtagtggaa aatcctattt
    30241 tattctcaca ttgattgaat ctctcctgca tacaaatgca aagctttata ttcttgaccc
    30301 taaaaatgct gatttggcag acttaggggc ggtcatgaat aatgtctatt accgtaaaga
    30361 agatatgttg gcatgtatca atcaatttta cgaagatatg attgatcgca gtgaaaccat
    30421 gaaacaacac cctaactata aaacaggaga aaattatgct tatcttggtt tgtctgccaa
    30481 ttttcttatt tttgatgaat atgtggcaat gatggatatg ctaggtcgtg aaagtaccac
    30541 cgttattcat aaactcaaac aaattgtaat gttaggacga caagcaggct tctttttaat
    30601 tcttgcctgt caacgtccag acgcaaaata ttttagtgat gggattcggg acaactttaa
    30661 cttccgtgtg gctttgggtc gtatgtctga aatgggcttt ggtatgatgt tcggaagcga
    30721 tacacaaaaa caatttttct taaaacccat caagggaaga ggttacgtgg atacaggaaa
    30781 aagtgtgatt agtgagtttt atacacccct tgtaccaaaa aggtacgatt tcttaggaga
    30841 aataggaaaa gtcattcaaa aaaagcaatc tgagcctgta ccgcacgaag tgaaaggtac
    30901 aggttcagac ttgctttgat tggtgtggcg ttagccacgc caatccttta gccccctcta
    30961 tctaacaggg gggcacaaat acaactgaaa acaggcaatt ctcatcaacc aatgttgatg
    31021 gtacaaagga ttgcggaaaa tatgaaaggt gtaaactcaa gggtcatagt ttacatcttt
    31081 tttagattgg aggtttgcga atggaaaacg aaaaaatttg gattaaggaa ttgaaagaaa
    31141 agcgactggc ttatggcgtt tctcaaaata aactggcggt tgcttctcat attaccagac
    31201 cttacctatc ggatattgaa acaggcaagg cagtccctac tcaacaggtg aaagaagatt
    31261 tactgaacgc tttggaacgc ttcaatcccg ataacccatt ggagatgtta ttcgactatg
    31321 tacggattcg attccctacc aatgatgtgg ctcaaattat cggtgaggtt ttacgtttga
    31381 atatggatta tatgctacac gaagactttg gctattattc ttatcccgaa cactatcgtt
    31441 tcggtgatat tgttgtccta gtctctcatg atgtaagtaa aggtgtttta ttagaactga
    31501 aaggaaaagg ctgtcggcaa tttgaaaact ttctattggc tcaacatcgg agctggtatg
    31561 atttctttca agattgcatg gaacataaag gtattttcaa acgcttggat ttagctatca
    31621 acgataaaac agggattttg aatattccag atttggcaaa gaaatgtaaa caggaagaat
    31681 gcatttccgt ctttcgaagc tttaaaaatt atcgcagtgg tgaattggtt caccgtgatg
    31741 aaaaaccata catgggaaac acactttata ttggctcatt aaaaagtgaa gtctatttct
    31801 gtatatatga gaaagattat gagcaatacg tgaaaaatga tgttccctta gaagacgcag
    31861 aagtaaagaa tcggtttgaa attcggttaa aaaatgaccg agccacccaa gccatgaaag
    31921 atttattggc acatcaacag gcggaaaaaa cagcctttga aattatcaat cgctatatcc
    31981 gctttgcaga taaagacgac actaaacgtc ggagtgattg gaaaactaat gaacgttggg
    32041 aatggtttat cggtaaaaat cgtggagcat tacgcctaac cacacagcca gagccttatt
    32101 cttttgaacg aacattgaac tggttacatc atcaagtcgc ccctacatta aaaatcgcaa
    32161 gcattttaga tgttctcaac ggtacaacca ttatctccac catgattcag gaagccaaac
    32221 tgacagaaaa acatgagaaa ttaattgaac aacaacatct agccatggag gatttgatta
    32281 catgagcctt ttaacaaaag aattaaagaa gttagggttt cagtgtggca ttgagtttca
    32341 agcgtatata caaaatacag ggaaatatac gtctctcatt attgagggaa aacggcaagc
    32401 tggtgatacc atctatacct atgattttta caaggtgaga ttttataata attataccaa
    32461 tcgagtaacc gtctatggag agcatttaac cccttttcaa ttattaaggc gtgtaaaaag
    32521 ctatatctat tatcgagaaa aatatcttaa ggaaaggagg acaatcacat gaattttggg
    32581 cagaatttgt acaactggtt cttggataat gcacagtcat tggtattgtt agcgattgtt
    32641 gtcattggac tgtttttagg ttttaaacga gaattttcaa aactcattgg cttcttgatt
    32701 attgctctaa tcgccgtcgg acttgtgttc aatgcagctg gcgtgaaaga tgtgttatta
    32761 aacttattta accgaatcat tggtgcttaa cagatatttt tcatgataaa ataggaagta
    32821 tatattttgt tatgaaagga tttatgaata tgtttacaaa tgatcaattt aaatctcttt
    32881 taattaaaac attagaaaga aagagctctt caaattatta tgaaggaggt aacgagattg
    32941 tttctaaaat gaaaatatca gaggtaactt tagatgagac tgacgatttt acttattata
    33001 aaggatataa aaagggctgg aatacgcttt gcacatatct taaaataaga gttccttttg
    33061 atgatttaga cttttttgaa agtcataaag atttgattac ccagacagca agctccatat
    33121 atgataaaca aggtgataat gtattagtgg atactatttt agtaccactt ccagagaatt
    33181 acgaagtaat taactttagt cagttgaaaa ttagtgatgt ggtttcacaa gctattgaag
    33241 acgctgagtc ttttatgagt aatggtgaat atcaacgtgc ctttgacaga gttcacactg
    33301 cttttcatgg atatttaatt gaaatactaa aaaaatatga aattacagtt cctagagacg
    33361 aaaatctatc taaattatat agtaggatac aacaattaat tgaaaaagaa attcaaccta
    33421 ctgaacttgc tgatatagtg aagacaacga taaggtcatc aaatggaatg attagctctc
    33481 ttaatgaagc aagaaatagg cattcacttg cacaccctaa tacaaatatt attggaaaga
    33541 gagaagcaaa actaataata ggtatttcaa gtacagttac agattatatt agcggatacc
    33601 ttgataagta gcgtcattaa ctgattgcta ctttttttat gactattttt ataaaaagga
    33661 tgtgataaga attggaaatg aaagtctatg tggcaaattt aggacggtat aatgaaggtg
    33721 aattagtcgg agcatggttt actccaccaa ttgatgagga agaaatggca gaaagaatcg
    33781 gtttaaatga ggactacgaa gaatatgcaa tacatgattt tgagcttcct tttgatgtgg
    33841 acgaatacac gccgattagt gaaatcaacc gtctatgtga agccattcaa gaaatcgaag
    33901 gtacacctat ttataatgaa ctcaaagaaa ttcaaggcat gtggtttagt agcttggaag
    33961 aattactgga aaacaaagag gatattcatt gttatagtga ttgtgattcg atggaagatg
    34021 tcgcccgtta ttacgtggaa gaaacaggac agcttggtga agtcccttcc aatttacaaa
    34081 attatattga ctaccaatct ttgggacgtg atatggaaat agagggtaat tacctagtta
    34141 cctctcatgg ggtatttgaa tattgtcagt aagtttaaca atccgtgtta taattaaatt
    34201 aataaatagc acggagaggt ataaattatg gtaaatgtat ttgaaaatct taaactatta
    34261 aaactagaca tgaaagataa aggctgggtg atagattcct tttactttcg ttacaaacag
    34321 caaaattata ttgtacttgt taagctattt gaaaaagagg aaaaagttcc agaatatgct
    34381 ctgttaaaac tagaattttt aaaggaaaac gatttttcag atatgctagc tgtctatgct
    34441 aattcggtaa aattatatac agacacgaaa acaataagag aatattttgg tatcgaatac
    34501 agtagtaact tgggagatgt tttatttcaa tttagccaaa ctcttgctcg atttattccg
    34561 acagaagtta gtgagaagaa aaatgaagac caaaaagaag ccatgtgttt ctcattaagt
    34621 caaagtgatt cagaagatcc cagaaaaaaa tattgttttt cagttagaag aaatccttta
    34681 aagggaaatg gtgagctggg aaaacgaagt ccttttaatg acaataaaac gagattgtat
    34741 agacccagct tatatgaacg attagggtca gataccaatt taagtttcag atattcaatg
    34801 aatccagatg atgaagaaac tgatgaaggt attattgcaa aatggacaaa aaataaaatt
    34861 gaatagttaa agcattgaaa gagcaatcac ctattttgat tgttcttttt ctatttttac
    34921 ggaaaggacg tgaagacatg aaaaaaataa gaagttacac cagtatttgg tcagtagaaa
    34981 aagtgattta tgcgattaat gatttacaac tccctttccc aattaccttt acgcaaatga
    35041 catggtttat cgtttctttg tttgtcgtca tactctttgg cagtttacca ccactttctc
    35101 tgattgacgg agcactactc aaatacttag ggattcccat tgttctcact gggttcatgt
    35161 gccaaaagac ctttgacgga aagaaaccct atggatttct aaagtctatc attacctatg
    35221 ctctacgccc taaagtaacc tacgctggca aacaaatacg attaaaaaaa gaaacaatga
    35281 atgaatcgat tacgattgta aggagtgaac aactagatgg catatccgat taaatatatg
    35341 gaagataatc tcgtatttaa tcatgatggc gaagtattcg cttattatga attaattccc
    35401 tataattaca gttttttaag ttccgatgaa aaaattcaag ttcatgataa tttctgtcaa
    35461 ttgattgccc aaaatcgtga tggcaagatt catgctctgc aactagcaac cgaatcaagt
    35521 attcgagcca cacaggaaca atcgaaaaaa gaaatcactg gacgattaaa agagatagct
    35581 tacgaaaaaa tagatgaaca gaccgaagcg ttaatttcta tgattggtga caatcaagta
    35641 gactatcgct tttttattgg ttttaaactc tacctcaatg aacaggaagt atccgtaaaa
    35701 aatgttggga aagaaattca aaaagcattt gcggaattct ttcatggtgt gaatcacaaa
    35761 ttaatgggcg attttgtttc tatgcctatg gcggaaatcg aacgcttttc taagatggaa
    35821 cagttgttag aaagtaaatt atccagacgc tttcagattc gtaaattgga gaaagatgat
    35881 tttggttata ttattgaaca tctttacggg caaacaggtg tcccttttga tgactacgac
    35941 taccatttac cgaaacgata cgaagataaa aaagtgttgg taaagaaata cgatattctc
    36001 aaacccactc gctgtttaat cgaagaaaat caacgctatt tacggattga acaggaagat
    36061 accactactt atgtggcgta ttttacaatt aatagtattg ttggtgaatt ggatttccct
    36121 aatagtgaaa ttttttatta ccagcaacag cagtttactt tccccgttga taccagtatg
    36181 aatgttgaaa ttgtcgccaa taaaaaagcc ttatctaccg ttcgcaataa aaagaaagaa
    36241 ctgaaagatt tagatagcca cgcatgggaa agcgacaacg aaaccagtac taatgtggtg
    36301 gacgctttag aatctgtcga tgaattagaa agtaatttag accaaaccaa agaatctatg
    36361 tacaaactaa gctatgtggt acgggtatca gcaaagaatt tggacgagct gaaacaacgt
    36421 tgtgatgaag taaaagattt ttatgatgat ctgtctatca aattagtacg accttttggc
    36481 gatatgctag gcttgcataa tgaatttatt ccctcaagca agcgatatat caatgactat
    36541 attcaatatg tcacgtcgga ttttttggct ggtcttggtt tcggtgctac acaaatgatt
    36601 ggtgaaaatt ctggtattta cgtcggttac aatctcgata caggcagaaa tatttatctc
    36661 caacctagcc ttgcaagtca aggaattaaa ggctctgtaa caaatgcatt agcgtccgct
    36721 tttattggtt cattaggtgg cggaaaatca ttctctaaca atatgctggt ctattattca
    36781 gtactctttg gcggacaggc aaccattgtt gacccaaaag ctgaacgtgg tgaatggaaa
    36841 gaaaccttac ctgatattgc ccatgaaatc aatattgtta atctcacgag tgagaacgac
    36901 aataaagggt tacttgaccc ttatgtgatt ttaaaactcc cgaaagattc agaaagcctt
    36961 gccattgata ttctcacgtt cttaacaggt atttccagcc gagatagcga gaagtttcct
    37021 gtcctgcgta aagctattcg gagtgtaact caaagcaaac aacgagggtt gttattggtg
    37081 attgatgaat tgcgaaaaga agatacgccc atcagcaata gtattgctga ccatatcgaa
    37141 agctttgtcg attatgattt tgcccatctg ttattcagtg atggcagtgt cacccaatcc
    37201 attagcttgg aaaaacaact caatattatt caagtggcag atttggtctt acccgattcc
    37261 aatagctctt ttgaagaata cactaccatg gaattattaa gtgtggcaat gctgattgtc
    37321 attagtacct ttgctttaga ctttatccac tctgaccgtt ccatttttaa aattgttgac
    37381 cttgatgagg cttggagttt tttacaagtg gcacaaggaa aagctctatc tatgcgattg
    37441 gttcgagcag gacgtgccat gaatgcaggg gtctatttcg ttactcaaaa cgcggacgat
    37501 ttactagatg aaaagatgaa gaataatatt ggcttgaaat ttgcctttcg ttccactgac
    37561 ctagtggaaa tcaaaaagac cttagaattt tttggtgtgg acaaggaaga tgaaaacaat
    37621 cagaaacgct tacgtgaatt agaaaatgga caatgtttag tttcagacat ctatggtcgt
    37681 gtaggggtta tgcagtttca cccgattttt gaagagttgc ttcatgcctt tgataccaga
    37741 ccgcctgtgc gaaatgaggt ggaagaatga cacaaaaaca aaagaaattt cttcactata
    37801 gttggataac gctcctttgt gtgggcgtta ttttactttt attaggcacg ctgggcaatg
    37861 cagtacaagc gacaggctta gttgatgaaa ccattgatac aagcaatgaa tactccaagt
    37921 atggtttgaa tcaatatcag cttgattatt atgtggacaa tagctggggc tggcttccat
    37981 ggaattggag tgatggcata ggacaatcgg tgatgtatgg attgtatgcc attactaatt
    38041 ttatttggac aatttctctt tatctatcga acgccacagg ttatttggtg aaagaagcct
    38101 atgccttaga tttcattagt caaacatccc aagcaattgg cgaaaacatg cagacgattg
    38161 caggcattac accgaatggc ttttccagtt cagggtttta tgtcggtttc ctccttcttt
    38221 ttattctcat tgttggaatc tatgttgcct atacaggatt ggttaagcga gaaacgacga
    38281 aagtgatacg agctgtttta aactttgtcg tggtgtttat tctatcggct tcctttattg
    38341 cgtatgcacc cgattatatt gcgaaaatca atgatttttc caaagatgtc agtaccgcca
    38401 gtctgaatat tgggacaaaa attgttcttc ctaacacgga tagtcaaggg aaagacagtg
    38461 tggacatgat acgtgacagc ttattctctg ttcaagtaaa gcaaccatgg ctattgcttc
    38521 aatatggctc cactgatgta gaagcgttag gggaagaacg tgtggaaagt ttattgtcta
    38581 ccagtccaga tacaaacaat ggtgaagata gagaaaatgt agtgattgaa gaaattgaag
    38641 atcatgacaa tacctattta accctaccga agacgatttc cagattagga acagtcttct
    38701 ttttgtttgt attcaatatt ggtatctcga tttttgtttt ccttctaaca ggaatcatga
    38761 ttttttcgca agtgctattt attattttcg ctatgttttt gccaatcagt ttcctattaa
    38821 gtatgttgcc gagttttgat ggcatgggca ggcatgccat taccaagtta tttaatgtga
    38881 ttatgacaag ggctggtatt accttgatta ttaccgttgc ctttagtatt tccactatgc
    38941 tttattcgct gtcagcaagt tctccctttt tcatgattat gtttttacaa attgtgacct
    39001 ttgcagggat ttattttaaa ctgggcgatt taatgagcct attcacttta caaagcaacg
    39061 actctcaaaa catgggcaga caagtgtttc gcagacctcg tcaaatgatg aatcgacaaa
    39121 ccagaagatt tcaacgcagt atgagtaaga tttttcgtgg aaaagcaggg tcaacgaagc
    39181 aaaagacaat gacaacaaag cagaatcaaa ccaataaagc taaccatact cgtcaaaatg
    39241 aacggactac accaaagaaa gaaacagcac tttccaatgt gaaaaagcaa caaggcggta
    39301 tcgggcaacg attaggtgaa aagacagccc atgtattgga cacgaaaaat cgtctagtca
    39361 ataaaagaaa gcaggcaaaa caacagatac aggcgacacc aacccatgtc aaatatgccc
    39421 ttcatcaagg aaaagagaat gtcactcata atgtaacaga ctttaaacaa tctatggcag
    39481 ataccaaagc tcaacgcaaa caacagcgta tgaaccagca ggagcaaaaa cgaaagaaca
    39541 ttgctcaaaa gcgtttggag ctggataaag caaaagaaaa aagacgaaaa gaaaacccat
    39601 catctcctgt tcagaataac cagcagcatg ttcgcaagcg tcagcaaacc gtcacgcctg
    39661 ttttgtcaca aaacactaaa cgtgaaaatc atcagcgacc attgaaaaaa gagcaaaaac
    39721 aaaagacacc accgaagcaa ttcaatcaga ggaagctaaa taaaagaacg gataagcgag
    39781 gacaacaaac atgaagctaa aaataacagt gatttgtagt gtggtcttct ctctcttctt
    39841 ttttctctta ttattcctag tcattttctt tgcagatgat acggacagtg gcgaaaacaa
    39901 caaggattct tctattccac aaggcggtgt gaccgtttca ccagaagtgt tggcacaccg
    39961 tccgttgatt gaaaaatatg gtaaggaata tgggattgaa gactatgttt cttatatctt
    40021 agccattatg caagtggaat cgggcggtac agcagaagat gttatgcaaa gttccgaatc
    40081 tttgggttta ccgcccaaca gtttgagtac cgaagagtcc atcaaacaag gggttaaata
    40141 tttcagtgaa ttattaacca gtgcagaaca acaaggagtg gatatagatt ctgttatcca
    40201 atcttataat tatggcggtg gctttttaaa ttatgtgagg agtcatggga aaaaatatac
    40261 ctatgaatta gccgaacagt tttctaaaga gaagtcgggt ggtcaaaaag cagactatcc
    40321 caatcctata gccatacctg tgaatggtgg ttggcgatat aactatggaa atcagtttta
    40381 tgttcagttg gtttcacaat acctaaccga cacttcccca acagaatttg atggtgaaac
    40441 cgtgcaagtc attatggacg aagccttgaa atacgaaggg tttccctatg tctttggagg
    40501 ggcgtcgcct accacctctt ttgattgtag tggcttaata caatgggtgt atgacaaagc
    40561 tggcatttct ctccctcgtg tcgcccaaga tcagtatgac gctacgcaag aaatctctat
    40621 ggaagaagcc caagcaggcg accttatctt ctttcattca acctataatg caggcacata
    40681 tgtgactcat gtggcgatat atttagaggg aaatcgcttt tatcatgcag gcgacccaat
    40741 cggttatggc gacttaagca gtcgttattg gcaagaccat ctgattgggg ctagacgtgt
    40801 tattcataac taagaaagga atgaatcaaa tgattataaa aatcgagcga aaagaaaaga
    40861 aggagaaacc aaagaaatct aaaaaaccga gcaagcaaag aaaagttccg atgattaaag
    40921 ttggcacgca taagaaatta acctttgttt tatgggtttt attgattggt agtgtcggat
    40981 ttggaatcta taaaaatttt actgccattg acactcatac tgtccgtgaa acagaaatca
    41041 ttaaacagca gattgtcgat accaaccaag tagaaagttt tgtgaaatcc tttgcgaaag
    41101 actacttttc gtggcaacaa tcccaagaag ccattgataa acgaaatgaa aaattgaccc
    41161 attatttgac ggaagaattg caggtattaa atgaagaaat gattcgtaag gatattccta
    41221 ctagttctag tgtgaacgat atacaggtgt ggcaggtttc tcaagtgaat gagaacacct
    41281 ttgaggtact gttttctgtt gaacaagtta ttaccgaaga caaagacaag gaaactatat
    41341 cgtctagctt tcatgtggtt gtccatatag atgaatcaga taatatggtt attatcaaaa
    41401 atccgacaat gagtaagaaa cctcaaaaat cggactacca acccaaacag ctagaaagtg
    41461 accatacagt agatacagaa acgatggacg aaatcactag ctttttagaa acgttcttcc
    41521 agctctatcc taccgccaca gaaaaagaat tgacttacta tgtaagtaat catgtgttac
    41581 ctatgattaa caaggaatat gttttcgagg aattggtgaa tcctatcttt accagaaaag
    41641 ataaccaagt aatcgtgaat gtcgctgtga aatatttaga tcaagaaaca aaggcaaccc
    41701 aaatctcgca atttgagttg atattagaaa aacaagataa ttggaagatt gtaaaataac
    41761 aaatattggt acatgattac agatactttg taatcatgta ctctttttga taaaaaattg
    41821 gagattcctt tacaaatatg ctcttacgtg ctattattta agtgactatt taaaaggagt
    41881 taataaatat gcggcaaggt attcttaaat aaactgtcaa tttgatagcg ggaacaaata
    41941 attagatgtc cttttttagg agggcttagt tttttatgcc cttttgggtt tttgaatgga
    42001 ggaaaatcac atgaaaatta ttaatattgg agttttagct catgttgatg caggaaaaac
    42061 taccttaaca gaaagcttat tatataacag tggagcgatt acagaattag gaagcgtgga
    42121 caaaggtaca acgaggacgg ataatacgct tttagaacgt cagagaggaa ttacaattca
    42181 gacaggaata acctcttttc agtgggaaaa tacgaaggtg aacatcatag acacgccagg
    42241 acatatggat ttcttagcag aagtatatcg ttcattatca gttttagatg gggcaattct
    42301 actgatttct gcaaaagatg gcgtacaagc acaaactcgt atattatttc atgcacttag
    42361 gaaaatgggg attcccacaa tcttttttat caataagatt gaccaaaatg gaattgattt
    42421 atcaacggtt tatcaggata ttaaagagaa actttctgcc gaaattgtaa tcaaacagaa
    42481 ggtagaactg tatcctaata tgtgtgtgac gaactttacc gaatctgaac aatgggatac
    42541 ggtaatagag ggaaacgatg accttttaga gaaatatatg tccggtaaat cattagaagc
    42601 attggaactc gaacaagagg aaagcataag atttcagaat tgttctctgt tccctcttta
    42661 tcatggaagt gcaaaaagta atatagggat tgataacctt atagaagtta ttactaataa
    42721 attttattca tcaacacatc gaggtccgtc tgaactttgc ggaaatgttt tcaaaattga
    42781 atatacaaaa aaaagacaac gtcttgcata tatacgcctt tatagtggag tactacattt
    42841 acgagattcg gttagagtat cagaaaaaga aaaaataaaa gttacagaaa tgtatacttc
    42901 aataaatggt gaattatgta agattgatag agcttattct ggagaaattg ttattttgca
    42961 aaatgagttt ttgaagttaa atagtgttct tggagataca aaactattgc cacagagaaa
    43021 aaagattgaa aatccgcacc ctctactaca aacaactgtt gaaccgagta aacctgaaca
    43081 gagagaaatg ttgcttgatg cccttttgga aatctcagat agtgatccgc ttctacgata
    43141 ttacgtggat tctacgacac atgaaattat actttctttc ttagggaaag tacaaatgga
    43201 agtgattagt gcactgttgc aagaaaagta tcatgtggag atagaactaa aagagcctac
    43261 agtcatttat atggagagac cgttaaaaaa tgcagaatat accattcaca tcgaagtgcc
    43321 gccaaatcct ttctgggctt ccattggttt atctgtatca ccgcttccgt tgggaagtgg
    43381 aatgcagtat gagagctcgg tttctcttgg atacttaaat caatcatttc aaaatgcagt
    43441 tatggaaggg atacgctatg gttgcgaaca aggattatat ggttggaatg tgacggattg
    43501 taaaatctgt tttaagtacg gtttatacta tagccctgtt agtactccag cagattttcg
    43561 gatgcttact cctattgtac tggagcaagc ctttagaaaa gctggaacag aattgttaga
    43621 gccatatctt agttttaaag tttatgcacc acaggaatat ctttcacggg catataacga
    43681 tgctcccaaa tattgtgcaa atatcgtaaa tactcaactg aaaaataatg aggtcattat
    43741 tattggagaa attcctgctc gatgtattca agattatcgc aatgatttaa ctttttttac
    43801 aaatgggctt agtgtttgtt tagcagagct aaaaggatat caggttacca ctggcgaacc
    43861 tgtttgccag acccgtcgtc taaatagtcg gatagataaa gtaagatata tgttcaataa
    43921 aataacttag tgcgttttat gttgttatat aaatatggtt tcttattaaa taagatgaaa
    43981 tattctttaa tatagatttg aattaaagtg gaaaggagga gattgttatt ataaactaca
    44041 agtggatatt gtgtcctatt tgtggaaata aaacaagact acgaatacga gtggatacta
    44101 tacttaaaaa tttcccttta tactgcccca aatgtaagaa cgaaacttta attaatgttc
    44161 aaaaaatgaa tataataaca atcaaagagc cagacgccaa gacgcagagc cgataatttg
    44221 agaaatgaaa ctctcatctt atcggctctt tttgtttatc tgaattttac tgactagcct
    44281 tcaatatttc ttgcttcatt gatacctttt gctagtgctt ccattaagga tagttctttg
    44341 tctgtaaagc tatccatgta tttttctacc tgtaaccttc gagtgctttt aatcaaatta
    44401 tctgtaggta agaaaaattc atcaatagat acatggagta atgatacaag atcatacagc
    44461 acttgtgtac ttgggtgttg tcctttgttt tctatatttg ttaaataacg tgggtcaatt
    44521 tcaatcattg ttcccacttg ttcacgagtg agaccccgtt tcattcgagc ctctttaatc
    44581 gctaaaccaa cggctctaaa atcgtattta tcttcttttt tacgcatact aaatcacctc
    44641 tatacatttt actgttccta tataaccata aacaggtata gaaaaacatg ttatatagtt
    44701 tatgagttcc tatagaacac tgtggaattt attaatgcga tgaatccaat ttcaaataga
    44761 aaggtcgctg attttattta cctatacaac tttataaaat ttagtcatac tcctagaaag
    44821 tagataaaat tggcgactta atggagggaa aagtcgccat gagaaagata atctgtcatc
    44881 tagttctctt aattaagttc ttatcaaaaa aacttatcca cctgtactgg atagatatga
    44941 ccatcaatgt ggttttgcag attacataga tagaaaaatc aaagcatatg aacagagaaa
    45001 acaatctgtt tatgtgcttt tttggtcact taataaatat cttttaggat ttctcttcat
    45061 ttatgcaaca aatccccctt tcgtgtcggg gtttagtatg aagggagata aagaagcaca
    45121 tgccactccc tttcacgaca gaaagggggt gaaaagcatg aaaccatctt cttttcaaga
    45181 aaccatagaa aatcagtttg actatatctg caaacaagtt attgaagatg aacgaaaaga
    45241 ttacttcaaa catctagaca gactatcagc aaaagaagtc tcgttttctg atatagataa
    45301 ctaccttgtc aactcttttt ctactgttga tacgtacgtc actgatttcc aactatttaa
    45361 attatttgga ttaagaatca atgttgaaag tgatttatta agtgaagccc tgcgtcatct
    45421 ttcagagaaa aaacggaaca ttattttact tcattacttt atggatatga gtgatgtgga
    45481 gattgcggag ttactaaatt tgaatcgttc gactgtttat cgtcatcgaa taagtggact
    45541 agccatgatt aaagaattca tgaaggagtg taaagaatga aaacagctta tccaagggtt
    45601 cccttccccc tcattgtaaa ggcgacagat ggcgacgtgg aagcaattaa tcagattgtt
    45661 aaacattatc gagggtatac ctcaaaacgt tcattacgtc gcatgacaga cgaatatgga
    45721 aattctcata tggttattga tgaaacccta cgtggcagaa tggaaacgaa actcatctct
    45781 aagattttat cgttcgaaat taaatagtcc cattttttcg tggaagcgtg tcgaatcgta
    45841 tccacgcttc ccgatttggg aggtttgtta ttccatcaaa gcatattgtg tgttcagtag
    45901 gttttgatag gctaacaagc caaacgttct ttgacaacca aataaaggca atcgaatacg
    45961 tttcggtaag aaaagagctg atgaactaac acgccatgac ctacaaaatt agtgagcgat
    46021 tcatgttagt aattcgaaag taatctttag caggattgct gccatgactt tcttatcgtg
    46081 ataatgatac tcccgtatag ccatagtccg agcgttagaa gcgtcacagg caatgggtac
    46141 ggctacatga gaaccatgca gaagtgaaat tcctgtgagc tttgctagag ctgttcgatt
    46201 gctaagatat tcttctcttg tcagtgtatt attataaaac tatttgatat aattataggt
    46261 gaatattgga gttttcctag cctataattg ggaaaggagt aataatgata acggtcacaa
    46321 aaaaggattt agttgagcta ggatatggaa cttctttttc agcagacatc ataaaaaaag
    46381 caaaagaatt gatgattaca aaagggcata tctactatca atctcgaaag ctagatagag
    46441 tccctcgtga agctgttgaa gaaattctag gaattcggtt ttcaaatgaa aacaggtctg
    46501 agtagttttt gcacagtaag gagtaaaaac tatggttaaa gacccaataa aaaaagcaaa
    46561 gaatggaacc tattattttc gtgcaaatct aggttatgat tctaaaggga aaaaaattca
    46621 aaaatatcgt agtggattca ctactaaaaa agaagcaaga gaagaatatt cgaaactgct
    46681 attgatgaaa ccagaagaat taagtgagaa taaggataaa atgacgttta aacattatat
    46741 ctttgaaatt ttccttccat ggtataagac acaggtaaag ctcagaacat atgaaaatcg
    46801 cttaccaact attaagaagc atttctctta ttttgataaa atggctgttt ccgatattga
    46861 gcctattgat gtgcaaaatt ggcaactaaa attatcaaag aagtgtaagt cttcttatgt
    46921 aagagctgtt caaggactat tttcagttgc tatggatcga gcaattgtcc ttgggataac
    46981 caccacaaat ccatctaaga ttattggcaa tgtgaaaaag caaaagtcta aaattgaatt
    47041 ttggacaaaa gaagaatttg aaaaagtaat ctctctaatt tacaaagaag attactatca
    47101 acacttttta tttatctctc tgtggttttt atttatgact ggaatgcgaa ttggtgaagc
    47161 tactgccatt caatgggaag atattgattt tgactcagga gtactaacca tcaacaaaac
    47221 actctattac aagaatcaat cgaattatag atttgttgaa ccaaaaacaa aggcgagcgt
    47281 tcgtcatatt gtattagata aatgcacatt aacttattta tccgaatgga aggaagtaca
    47341 acaaaatcta attcagacag actttgtaat gagctataac ggtattccta cccaaaaaca
    47401 tacactatca tatgctattg aacgctatgc taagctggct ggtatccatc gaatcagaat
    47461 ccatgggtta cggcattctc atgcttcctt gttaatcagt atgggagaaa atccacttat
    47521 cattaaagat cgtctaggac acgaagatat tgagacgact ttaggaacgt atggacatct
    47581 ttatcctaac agtaatttcg aggtagctaa caaattaaat ggagccattt cctttaaaga
    47641 agcaaaacaa aattatgata cttcaccaaa gaatcaattt actgtagact acttgcgaaa
    47701 caaagaaatg aaaaaagtgc aataaaagtg cagtaaaaag ataagaagag ccagaaaccc
    47761 ttggtataag aggatttcta gctctcctac aactattccc actccactgt tgctggtggt
    47821 ttagaagtga tgtcatacac gatacggttg acgtgggcta cttcgtttac gatacgtaca
    47881 gagatttttt gcaagacttc ccatgggata cgggcaaagt cagcggtcat tccgtcgatt
    47941 gaagttacag cacggatacc gactgtgtag tcgtaagtac gtccgtcacc cataacaccg
    48001 acagagcgga tccctggaag aacagtgaaa tattgccaga tatcacggtc aagtccagca
    48061 gctgcgattt cttcacgcaa gatagcatca gattcgcgta cgatttctag cttgtcttca
    48121 gtgatttcgc caagaacacg aataccaaga ccaggaccag ggaatggctg acgccaaacg
    48181 attgaatcag gcatgcctaa ctgagtccct aattcacgga cttcgtcttt gaataatgtg
    48241 tttaatggtt cgatcaattc aaattgcata tcttctggca gtccacctac attatggtga
    48301 gatttgatcg tctgtgctgt ttctgtacca gattcgataa cgtcagtata caacgttcct
    48361 tgtgctagga aagagacgcc ttcttcacca gcaagttttg ttgcttcgtc atcaaaaaca
    48421 tatacgaatt cattcccaat gattttacgt ttttgttctg ggtcagatac acctttcaac
    48481 ttgtctaaga agcgatctct tgcatcgact ttgatgatgt tcaagccgaa ttttccgcct
    48541 agactttcca ttacttgttc cgcttcgcct ttgcgtagca gaccgtggtc aacaaagata
    48601 gatgtcaatt ggtcaccgat cgctttttgt aaaagaaccc caacgacact agaatcaacg
    48661 ccacctgaaa gaccaagcaa gacttttttg tcaccaactt gttcacggat tttttctact
    48721 tgcatatcga taaagttatc cattgtccag ttaccttcac agtgacaaac atcaaaggca
    48781 aagtggcgca gcaattcgat tccgtattcg gaatgacgta cttctgcatg gaattggata
    48841 ccataaaaat tacgtgttgt gtcttggata gaagcaatcg gacaatcttt gcttgttccg
    48901 actgtttcaa agccttcagg aactttagtt accaagtcac catggctcat ccatactgtt
    48961 tgttgttttg gtgtttcttt aaacaagaca gcttgatcgc ttgttacttc taacaaggct
    49021 ttcccatatt cgcggttttt agcaggctct acggaaccgc caagtttgta cgtgatcaat
    49081 tgcataccat agcaaatccc taatacagga atacctaaat tgaagatctc aggatcgatc
    49141 ccaaatgcat tctcatcata tacactgttt ggtccgccag aaagaatgat tccctttgga
    49201 ttcatcgctt ttacttcttc tgcagtaatg cggtggctca ataattcgga aaagactcca
    49261 agatcacgaa tacgtcttgt gatcaattgg ttatactgac taccgtagtc taatacgata
    49321 atcttttcaa cgttcgtcat atcggcaacg tttgtcaaat ttattacccc tatcccttta
    49381 aattttatct caaaatagtc aaactatttt aaaatgctaa tattttcgca tgaaaatcga
    49441 atcgatgata tgattttcag ttttatggag aattatatcg gctcttcctc gtgtaggcaa
    49501 gatatattcc tgtaaatttt tcaaattcac atttttccat acatcttttg ccattttaaa
    49561 ggcttcttca cgatctccga tagcaaaacg ataataataa ttctctggat tttggaaagc
    49621 cgtatccagt aacgcaccaa aacgatccaa ataccatttt tcgatcagca cgggatcggc
    49681 atcgacatag acagaaaaat caaaaaagtc gctgacgtag atttgctgat tcgcaggtaa
    49741 ttgaagcgta ttgatcccct caacgatcaa gatatcaggc tgctggatca attcgtactt
    49801 gtctggaatg atatcataca catcatgtga gtaaacaggt acttttatct cttcctgacc
    49861 agattttaca cggttcaaga aatcgatcag catctccata tcataacttt caggaaatcc
    49921 tttacggtcc atgattccac gctcttttaa tatacgattt ggataaagaa atccgtcagt
    49981 cgtgatcagc tgaacgtttc ttcgtttgaa ggtacgagac aaaatcgtct gcagcagtct
    50041 ggctgttgta ctttttccaa cggctacact tccggcgatc ccgataataa aaggcggtac
    50101 ttctacgtat ttatgaagaa ataaaccttt actcaagaac aaagattcaa attctttcat
    50161 ataaagataa atcagatgag caagaggtac atagatatct cgaacatcct gcatggaaat
    50221 gcggtcattc aaacttttga tattatctag ttcatcttgt gtcaaaggtg cttgcccatt
    50281 acgataaaat tctcgccatt cttctcttgc cacacggtag tagttcattg gatcattcat
    50341 attagcctcc tgcgttctcc catcaatgga actattttaa cacaaaataa acgcaaaccc
    50401 caccacttaa gagagattgc cgatcttttt gtataatctt tataatagaa agaaacggag
    50461 tcttattctt gacttgcgca cggatacata aaaggataga ctgttgtcat gaaagaaatg
    50521 agaaggatgg aagacatgac aaatcattac tattctgaac gcccagatac ggcgcacgat
    50581 tttgaacaat gggcttttga gttaaaaggc agaacctttc aatttgtaac agattctggt
    50641 gtattttcac gtgaaacagt ggattatggt tcacgtgtcc tgattgatgc tttcgattgg
    50701 gaagagttac ctgatgaagg aaagatctta gatgtgggat gcgggtatgg accgattggg
    50761 ttagctttgg catttgcgac acagcggttt gttgaaatgg tcgacattaa tgaacgagcg
    50821 gtaagtctag cgcaaggaaa cgcaaagcgt aaccaaatcg aacatgttga tatccatcaa
    50881 tcgaatatct atgaagcagt tcatgaagaa acctatgcag ctatcgtaag caatccgccg
    50941 atccgtgctg gaaaaaaagt tgtacatgaa attttgacag gcgcatatcc tcggttgaag
    51001 aagggcggta cactgacaat tgtgatccag aagaaacaag gagcgccgag tgcgcaaaag
    51061 aaaatggaag aaacatttgg taatgcagaa atcgtcacaa aagataaagg atattatatc
    51121 atcaaaagtg tgaaagaata actagctgaa aaatagtgga gcgacgaaag agtggaactg
    51181 ggcgtgcatg tacgggtacg tatcagttct ttttttgttg agaagttttt aaaaacaaag
    51241 aactattttt tcttcaaaaa gaaatagtag gaacagagtc gttgtttttt acgataaaat
    51301 aaataagata cagaacttgt atagaaggct gccaagtcgg tagataaagg aggtttttat
    51361 caaaaaacat actttccttt tttctctatt cttttcttgg gggttttggt acactgatag
    51421 ggaatttaga tagaagggag ccaataggat gaagctgacc atcagagata tcgcagaaat
    51481 ggcaggcgta tcagtaacaa ctgtctcaca gattttgaat aacaaaggaa gcagatttag
    51541 tgataagaca agaaaaaaag tgttgtcgat cgtgaatgaa catcattata agcccgatta
    51601 tttcgcttca aatgtgatca atcgacattc aaagaccatc ggaatgatcg tccctgatgt
    51661 cactgatttc ttcttctcca aactgatcga aggtgtagag agctatttga atcctttggg
    51721 ctatgtgatc atgttatgca attctcgtca tagccaagaa aatgagatca agtatttaca
    51781 agagctttcc caccgctcag tggacggaat cttgctggcc acaccaaata ttttacctga
    51841 gaaatatgca ttagacagcg gtttttatca aaaaatgcca atcattttaa tcgatcgcgg
    51901 attgaatcgt cgggataacg gacggcttat cgtaaaggaa tatgagggcg cctatcaagc
    51961 tgtttcgctg tttattgaaa atggccatac gaagatcggc atgctgaagg aaaccactgg
    52021 atactatcaa ttagaagaac gtttcaacgg atatcgtcat gcgctgaaag atcatggcct
    52081 gccttttaat gggaaatttg ttgaacatgg agagttgact gtccaaggtg gatatactgc
    52141 atcaaaaaaa ttactcaaac ataaagatat cacggctatt ttttgcggga atgatgccat
    52201 ggcgatcgga tgctatcagg cgatcgatga attgggcaaa aaaatcccag aagatatctc
    52261 agtcatagga ttcgatggat taaagctgtc agaatacatg attccgcaat tgacgacagt
    52321 gcagcagcca agttttgata ttggatttta tgctgcacgt ttcctgatcg atacgatcga
    52381 atttcctcaa agaaaagttc cgaacaaagt gttcgaaaca aaattaatta ttcgtgagag
    52441 cgtaaaagta ttgacaaagg gctaactcgg cggtatattg cttatgtaag catttacaaa
    52501 ggctagttag tgcttttttt atttttagta aaccagttta ctaaagtggt ttacctttcc
    52561 taaaaataat gtataatacc gaatgaagac aaggaggatc aggcaatgcg aatggtggat
    52621 ctgattgaaa aaaagaggga tggaaacgag ctgtcgaaag aggaaatcga gtacatcgtc
    52681 acgaactata cgaatggaaa gattccagat tatcaagtca gtgcattatt gatggcaatt
    52741 ttttatcaag acatgacaaa tgaagaaatc acgaacttaa cattggcgat tgctaattct
    52801 ggtgatgtca tcgatttgag ttctcttgaa ggaataaagg tagataagca ttcgacaggt
    52861 ggcgttggtg acacgaccac attgatttta gcccccctag tagctagtgt cggagtgaca
    52921 gtggctaaaa tgtctggacg cggtctaggt tacacaggtg gtacactaga caagctagaa
    52981 gcaattcccg gatttcagat cgagctttcg gatgaagaat ttgtacgcat tgttaatgaa
    53041 agtaaagtag cggtaattgg tcaatcagga aacttggcac cggcggacaa aaaattgtat
    53101 gccttgcgtg acgtcacagc gaccgttgat tctcttccgc tgattgccag ttcgattatg
    53161 agtaaaaaaa tcgcggcagg agcagatgca atcgttttgg atgtgaccac tggagacggt
    53221 gctttcatga agaacatcga agatgcaaga cgtctggcaa agaccatgac gagcattggg
    53281 aaactggcta accgagaaac agtggcggtt atctcagata tgtcagaacc tcttggcgaa
    53341 gctatcggaa atagtctaga agttgtcgag gcaatcgaaa cattacaagg aaatggtcca
    53401 gaagatctag tagaaatgtg ctacgcctta ggaagccaaa tggttgttct tgctggcaaa
    53461 gctaagacaa ccgatgaagc aagaacgttg cttcaagaag ctctggaatc aggtaaagcg
    53521 ttagcaaaat tcaaagaaat gatccaaaat caagggggag acccagcgat cgtggaacat
    53581 ccagaacgaa ttttgactgc acgctacaca atggagcttc ctgctaaaca aagcggagtt
    53641 gtgtcaaaaa tcgtggcaaa tgaattagga attgctgcaa tgatgctagg tgctgggcgt
    53701 aaaaccaaag aagaagatat tgatcacgct gttggattga aactgcataa aaaaattggt
    53761 gacactgtga caaaaggtga gtcactattg acgatctata gtaacgacga agaaatcact
    53821 tctgtcattg aattattata taaaaatatt gaaattggtg aatcggcaat gaagccaacg
    53881 ttgattcatg acatcatcac agaataaagg aaaaaagcgg actttaccgt tttaaagaaa
    53941 aggggaaaag aaatggaact aaaccgaatg atcgaccata ctattttgaa agcagacgca
    54001 tctaaagaag ctgtgatgca aattatcgaa gaagcaaaaa aataccattt ttattctgtc
    54061 tgcatcaatc cagcatgggt tgcgctagcg aaagaacaat tacaaggtga gccagtagcc
    54121 gtatgtacag taatcgggtt tcctctagga gcaaacacac ccgagacaaa agcatttgaa
    54181 acaacagatg ccatcaataa cggtgcagat gaagtcgata tggtcatcaa tatcggtgct
    54241 ttgaaatcaa aggatgatca acaagtccaa aaagatatcg aagcagttgt tgaagcagca
    54301 aaagatcgtg cgcttgtcaa agttattatt gaaacatcgt tattagatag agaagaaatc
    54361 atccgagctt gcgaaatagc aaaagctgca ggcgctgatt ttgtcaaaac atcaactggt
    54421 ttctcaacag gcggagcaaa ggtagaggat gtccgtttga tgcgtgaaac tgtaggacca
    54481 gaaatgggtg tcaaagcttc cggcggtatc cataacgaag aagaagcaat ggcaatgatc
    54541 gaagctggtg ctacaagaat cggaacaagc gcaggagtag caatcgtatc tggttcaact
    54601 ggtgaaggct attaattttt tcaaaggaga agctcatggc agaactcaaa caagaatgga
    54661 tcaacacagc tattgaagcg ttagataaag cctatgttcc ttattcccat tttccggtag
    54721 gcgcttgtct cgtaacggaa tcaggcaaga tttatcaagg catcaacatt gagaatgcat
    54781 catttggatt aacgaattgt gccgagcgca cagctttttt caaagcagta tctgaaggag
    54841 aaaaaacatt tacgcatcta gtcgtagcgg ggcacacccc cgatcctatc tctccttgtg
    54901 gtgcatgtcg acaagtaatg gcagaattct gttcccctga tatgccggtt acgctagtag
    54961 gagacaatgg tgtgacgaag gcaacgaccg ttcgtgcact gctgccttat gcatttactg
    55021 aaaaagatct ataactcatg ttcattcagt cagctgactg ttgaaaaata aaacaattat
    55081 tttaggaggc tttacagaaa tgaaaaaagc aaaattattt ggtttaggtg ctgtcgcact
    55141 agcagcaggg ttatttttag gtgcatgcgg caacaacggc tctactgatt catccggtgg
    55201 caaaagctca tcagacacaa caactgcagc attgatcaca gacacaggtg gtgtagacga
    55261 ccgttcattc aaccagtcag cttgggaagg actagaaaaa tgggggaaag atcaaggact
    55321 ttcacgagga aatgatggct tccaatattt ccaatcttca aatgaatcag attacatccc
    55381 aaatattgac caagcattga atgctggatt caaaacgatt tttggtattg gttataaact
    55441 aaaaccagcg atccaagaac aagcaacaaa caatacaggt acgaactttg ttattatcga
    55501 tgatgtcatc gatggattag ataacgttgt atctgcaact ttcaaagaca acgaagcttc
    55561 ttatcttgca ggtgttgcag cagcttatac gactgaaaca aacgtagtcg gctttatcgg
    55621 cggtgtaaaa ggtgaagtaa tcgatcgttt tgatgctgga ttcaaagccg gtgttgatgc
    55681 aggtgcgaaa gaattaggaa aagaaatcaa agtattgaat caatatgctg gtgacttctc
    55741 tgctccagat aaaggacgtt caattgctca aggtatgtat gcacaaaacg cagatatcat
    55801 cttccatgct tcaggcggta caggtaacgg tgtattccaa gaagcaaaat cattgaacga
    55861 atcaggcgac aaaaaagttt gggttatcgg tgttgaccgc gaccaatcag acgaaggcga
    55921 atacacatta aacggcgaaa agaaaaactt cacattgaca tctacactga aagcagttgg
    55981 aacagtagta gaagatttgg cacaaaaatc agcggacggt aaattccctg gcggcgaaca
    56041 cactgtttat ggattgaaag aagacggtgt tggtctaaca gaaggacaac tttctgacga
    56101 agcgaaaaaa gcagttgatg aagcaaaaga aaaaatcatt tcaggtgacg taaaagttcc
    56161 agaaactcct gaagaaaact aaaaccattt ctatagcctt gttagacaca tgtttgacaa
    56221 ggctatggtt tgattagaac aagaattgtt catttatcca agctgccttg tgacagtttg
    56281 gataagggaa caactccctg aagtaatgtt tgtttcaaaa gaagaacgct cactaagcgt
    56341 gaatcttagt caatcgttgc cctagataga aatcgttagg atgtgaaaaa aaggtggttc
    56401 aagaaaatat tgtcatagaa atgcagaata ttaccaaaga atttggaaca ttcaaggcaa
    56461 atgacaacat caatttacaa gtaaaggcag gagaaattca tgcgttgctt ggagaaaacg
    56521 gtgctggcaa atctacattg atgaacgtgc tttccggatt attagagccg acatcaggga
    56581 aaattttgat gcgtgggaaa gaagtaaaga tcacaagtcc gaccaaagcc aaccaattag
    56641 ggattgggat ggtccatcag cactttatgc ttgttgatgc ctttactgta acagaaaaca
    56701 tcgtgttggg aagcgagcct agtcgcgcag ggatgcttga ccataaaaaa gcacgaaaag
    56761 agatccaaaa agtttctgaa cagtatggat tgtcagtcaa cccagatgct tacgttcgtg
    56821 atatttcagt tggaatggaa caacgggtag aaattttaaa aacactttac cgaggagcag
    56881 atgtactgat ttttgatgag ccgacagctg tattgacccc tcaagaaatt gatgaattaa
    56941 tcgtgatcat gaaggaatta gtcaaagaag gcaagtcgat cattttgatt acgcataagt
    57001 tagatgaaat caaagcagta gctgaccgct gtacagttat ccgccgtgga aaaggaatcg
    57061 gtacagtcaa cgttaaagac gtaacctcac aacaattagc cgatatgatg gttggaagaa
    57121 cggtttcatt caaaacgatg aaaaaagaag cgaagcctca agaagtcgtt ttgtctattg
    57181 aaaatctagt ggtgaaagaa aatcgtggat tagaagccgt gaaaaacttg aacttagagg
    57241 ttcgtgctgg cgaagtactt ggtatcgctg gaatcgatgg aaacgggcag tcggagttga
    57301 tccaagcttt gactggtttg cgaaaggcag aaagcggaca tatcaagcta aaaggggaag
    57361 acatcactaa taaaaaaccc cgaaaaatca ctgaacatgg tgtaggacac gtgccagaag
    57421 accgtcataa atacgggtta gtcctagata tgacattatc tgaaaatatc gcactacaaa
    57481 cctatcatca aaaaccttac agtaaaaacg gcatgctgaa ttattcagta atgaatgaac
    57541 atgccagaga attgatcgaa gaatatgatg ttcgaacaac gaatgaactt gttcccgcaa
    57601 aagctttatc aggcggaaat cagcaaaaag caattatcgc tcgtgaagtc gaccgagatc
    57661 ctgatctgtt gattgttgca aatccaactc gtggactgga tgtaggtgcg atcgaattta
    57721 ttcataaacg tctgatcgaa caaagggaca aatacaaagc agtgttactg atcagtttcg
    57781 aattagaaga aattttaaat gtttcggatc gtattgctgt tatccatgaa ggagaaattg
    57841 tcggtatcgt tgatccgaaa gaaacatctg aaaatgaatt aggtctattg atggcgggct
    57901 ataccttaga agaagcacga aaagagttag aaaagggggc tggcgcacat gaatgatcgc
    57961 agcgaaaaat tccgtaattt attagtgcct gtactttcag ttgttttagg attgatctta
    58021 ggcgcgatat tgatggctgc ttttggtttt cagcccatcc aaggttattc ttctatgcta
    58081 gatgcagccc ttggttcgca aagagggata ggtgaaacgt taaggcaagc aacgccgttg
    58141 atttttacag cattaggttt ttctgtagct aactcagctg ggtttttcaa tattgggctt
    58201 tctggacaag cactttgcgg gtggatcgtc agtgtctggg tggcacttgc gtttccagat
    58261 ctgccaaaag ttgttttgct tccgttatgc gtgatcttag gtgccttagc tggtgcgatg
    58321 gcagcggctg ttccaggttt acttcgagca ttttttggaa caagtgaagt gatcgtaaca
    58381 atcatgatga actatatctt attatacgta agcacatttg ctttacatga agtgatgcct
    58441 gaaagctatc gctcaagttt ggactcttcc aatatgatca gtcaaaatgc ctcactgcgg
    58501 ttaccatggt taacacaagc ttttggcggc tctcgcgtaa actcaggatt atttttagca
    58561 atcatcgcgc ttattttcgt ttggctgctg atgaagaaaa cgactttagg atttgaaatc
    58621 cgttctgttg gattgaatcc ttttgcttct gagtatgcag gaatgagtag taaacgtacg
    58681 atcgttttgt cgatggtcat ttctggcgct ttggcagggc ttggcggtgt ggttgaagga
    58741 ttaggaacgt atcaaaactt ctttgttcaa acgacttcgc tatctattgg atttgacgga
    58801 atggctgttt ccttgcttgg ttctggatca gcaatcggta ttcttttatc agcgatcttg
    58861 ttcagtattt tgaagatcgg tggacttggc atgcagacag gagcaggtgt tccgtttgag
    58921 atcgtcaatg tatcgattgc tttgattatc ttctttgtcg ggatcaactt cctgattcgt
    58981 ttcgtcatgg ctaaagtctt ccaagggaaa aaacaagaag agatcgttgc gacaatagaa
    59041 tcgaaaccaa cgaatcaaaa ccatgaaggg ggcgaactat aatgtcgact atcgaattaa
    59101 ttgccttgat ccttacttct acactggttt attcaacacc gctaattcta acgtcactag
    59161 gcggaacttt ttctgaacga agcgggatcg taaacgtagg gctagaggga atcatggtca
    59221 tgggtgcttt tagttccatc gttttcaact tgacgatgag tccatcactt ggttctatga
    59281 caccatggat cgctatttta gtgggtggcg tcgtaggtat cctattttct ctgattcacg
    59341 cagtagcaac agtcagtttg cgtgctgacc atattatcag cgggacagta attaatctga
    59401 tggcacctgc tttaggtgtt ttcttgatca aagcatggta tggtaaaggt caaactgata
    59461 acatcacgca gaatctgggg tatttttctt tcccaggatt agcagatatt ccggtcattg
    59521 gaccaatttt ctttaaaaat acattcttac ctgcttattg tgctattttg attgctgtcc
    59581 tagcttgggt gatcatcttc aagacgaaat tcggcttgcg cctccgttca gttggtgaaa
    59641 atcctcaagc tgccgacaca ttaggtatca atgtatatgc tatgcgttat tcaggcgtac
    59701 tgatttctgg cttgttaggc ggtatgggcg gtgctgtttt tgctcagtcg atttccggta
    59761 acttttcagc tggtacgatc gttggacaag ggttcatctc catggctgct atgatctttg
    59821 gtaagtggaa tcctttaggg gcaatgggtg cctcattgtt ctttggtttt gctcaaagct
    59881 tgagtatcat tggcgcacaa ttaccagtta tttcttcgat tccgccagta ttgctgcaaa
    59941 ttgctccata tttgctgaca atcattgtgc tggttgtttt cttagggaaa gcttctggtc
    60001 caaaagcaaa cgggaagaac tatatcaaat caaaataatc ttttagcgaa taaaaagggt
    60061 gggttacggg aagtgttttt cgtctcgccc tttttgtttt aaaggcaata aaaataaaaa
    60121 gaaagaagga ataatcatgt ttaaacgcgt acatctgatc gtcatggatt cagtaggaat
    60181 tggagaagca ccagatgccg ataagttcgg tgatgttggt tctgatacat taggacacat
    60241 tgcgaaagaa gcaggattga acgttccaca tttagagcag cttggtttag gaacgatccg
    60301 tcctcttgaa ggtgtggaat cagtgaaaga tcatcaaggc tatgcgacga aattagaaga
    60361 agtttctgta gggaaagata cgatgacagg ccactgggaa atcatgggat tgaatatcaa
    60421 aactccattt cgtgtgtttc ctaatggatt ccctgatgat ctgatcaaac aaatcgaaga
    60481 attttctggc cgtaaagtcg tatgtaacaa accttatagc ggaacagctg ttattgacga
    60541 ttacggtgaa caccaaatga aaacaggcga tttaattgta tatacttctg ccgatcctgt
    60601 ccttcagatc gcggcacatg aagaaatcat tcctttagaa gaattatatc ggatttgcca
    60661 attcgttcgt gatataacaa aagatgatcc gtatatgatt ggccgaatca ttgcacgtcc
    60721 gtacgtgggt gaaccaggag acttcacacg aacaagcaat cgccatgatt atgcgttgaa
    60781 tccattcgga cacacagtcc ttgattcttt gaaagaagca ggaaaggacg tgattgctgt
    60841 tggaaagatc aacgatattt tcaacggaca aggaatcact gaatctgtcc gcacgaaaag
    60901 caatatggat ggcgttgacc agctgctgaa agttatgaaa aacgattttt caggaatcag
    60961 ctttaccaat ttagtagatt ttgatgcatt atacggtcat cgtcgggatg tagtcggcta
    61021 tgcgcatgcg attgaagaat ttgacttacg aattccagaa ttgcttgaag cgatggaaga
    61081 agacgacttg ctaatgatta cagccgatca cggaaacgat ccgacgttta ctggtaccga
    61141 tcatacgcga gaatatgtac cgttattggt ttacagtaaa aaaatgaaag aacaaggggc
    61201 attgcctcaa ggatattatt cagatatttc agcaacgatt gctgagaact ttagtgtttc
    61261 ttcgactgaa aatggcgaaa gcttcttgaa attattaaaa taatcttttt aaataggaga
    61321 aagcaaatga ccaagttaag cgagatgtta caagaaacga cccagtttat ccttgataaa
    61381 ggagtaaaag aaattgattt tggtttgatt ctaggttcag gattaggtga attagcagat
    61441 gaaatcgaag atgctgtaat gatttcttat gatgagatcc cgttctttcc tgtttcgaca
    61501 gtagttgggc atgcaggaaa gctagtttat gggtctctgg caggcaagaa agtgttagcc
    61561 atgcaaggga gattccacta ctatgaaggt cattccatgc aaacagtgac ctatccagta
    61621 cgtgtgatgg ccggactagg ggcccattca gtcattgtga ctaatgcatg tggtggtgtc
    61681 aacgaatcat ttgtaccagg agatttgatg ctgattaccg atcatatcaa ttttactggt
    61741 gaaaatcctt tgatcggtcc gaatgaagat gcaatgggcc ctagatttcc agatatgagt
    61801 caagcttata cgcctgacta tcaagcaaca gcaaaagcag cagcagaaaa actaggtttg
    61861 gatcttaaag aaggcgtata tatgggctat tctggaccaa cttatgaaac gcctgcggag
    61921 atccgaatgt ctcggacaat aggagccgat gcagtaggga tgtcgactgt tccagaagtc
    61981 atcgtagcag ctcacagcgg attaaaagtg ttaggaatct cttgtattac caacttagca
    62041 gcaggtatgc aagcgaatct gagccatgaa gaagttgtag aaacaactca gagagtcaaa
    62101 caatctttta aagcattggt taaagaaaca ttgacattat tgtaatagga ggaacaataa
    62161 aatgagtgtg catattgaag cgaaagaagg cgagatcgcc gataagattt tacttccggg
    62221 agatcctttg cgagctaaat atattgcgga gacttttttg gaagatccag tttgttacaa
    62281 tcaggtacgc ggtatgttag gctttaccgg caaatataaa ggagaacgta tttctgttca
    62341 aggaacagga atgggaatgc catcagccac catctatgcc catgaattga tccagtcgta
    62401 tggtgtaaag aaattgattc gagtaggtac atgcggtgca ttgtcaaaag acgtccatgt
    62461 tcgtgattta gtactagcac aaggtgcagc gaccagttct tcgatgatcg aaaaaaattt
    62521 ccaagccttt cattttcctc caatcagtga tttcaatcta ttactgaaag catatgagat
    62581 agctaaagaa aagggctata cggttcatgt aggaaatgtt ctttcggaag attctttcta
    62641 caaagatgat ttgacagaga cgttccaatt agctgaactt ggcgttttag gagtggaaat
    62701 ggaagcagcg gctctttatt acttaggcgc gaaataccat gtgcagacat taagtttgat
    62761 gaccgttagc gaccatttga tcaccggtga agaaacaaca gctgcagaac gtcaatctac
    62821 gttcaatgaa atgatcgaag taggattgga aacagcgata gcagaataag aaggaaatga
    62881 aaaagctgcc ctgcattaag taataagaac atccaagcaa aaatagctcc tcatgttttt
    62941 gacttggctg gacttattat tgcaaatgta agcttttgaa caccgtttac caagaggttg
    63001 tgaatctgcc gtttaactct gagtcacaag gaacaatttc aaaaaacagc ttttcatgtt
    63061 tgatgaatat tgtgacttgt gaccgagaag ttggcaggag aaaaccgttt atacgaaaaa
    63121 agggactgtg acaaatcgtg tcacagtccc ttttttatag tgttttttat aggtagtatt
    63181 ttttagcaac tgttaagtca tcatttaatt cataaacaag tggttgacct gttggaattt
    63241 caagatccat gatgtcttcg tcagagatac cttcgatatg tttagctagg gcgcgtaatg
    63301 agttaccatg tgcagctact aaaacagttt tgttgtctag taatgctgga gcaatttcat
    63361 cttgccagaa tggcaaagcg cgttctaatg tcactttcaa gttttctcca ccaggaatat
    63421 cgcgtttgtc taacattgcg taacgacggt catttgctgc agaaccttcg tcagtttctt
    63481 ccattaatgg aggaagagta tcgtaagaac gacgccagat gtgcacttgt tcgtcgccgt
    63541 atttttcagc tgtttctttt ttgttcaaac cttgtaattt accatagtga cgttcgttta
    63601 agcgccatga tttgatttgt ggtacccaaa gttgatctga atattctaag atcaagttac
    63661 atgttttgat tgcacgagtt aaaacagaag tgtaagcaac atcaaattcg attccagctt
    63721 ctttgatttt gcgtccgcct tcttttgctt cttcgattcc ttctggtgct agatttacat
    63781 cagcccaacc agtaaattgg ttcaatgcat tccattcact aagaccgtga cgagaaaaaa
    63841 ctaattttgg catgtttagc tctcctttta agataggttt atatttctga aattttcagt
    63901 tctgttttat tgtacaattt tttggaagag atttccatcg aaaaattaga taagattcta
    63961 tgagaaaaca agtagagaat ataaaaaaac gaacagtgcc cacgcaactg ttcgttttta
    64021 ggtattagat gcataattgc tcgatttctt tttcaggtaa attgatatat ttataacatg
    64081 ttccaactga aacaccgcat tttgaagaaa taaattggat cgtttctttt ttttcataat
    64141 agagacgtcg gatttttttg atcgtttttg catcgatttt tggtcttccg ccgatttttc
    64201 cttttttacg agcttcatct aatccaacta atgtacgttc tttgatcaat gcgcactcca
    64261 tgtttgctag gttttccatt aattggaaat agatttttcc catttcgcgc gtatcgattc
    64321 cttcatcaag actaatcaag tgcagcccgc gatctttgaa taattgcgtg agttctgtta
    64381 attgccgcgt agatttgcct aatcgatgaa gttggcaaat gactagtgca tcgccttgtt
    64441 gcatgtcagc gatcactgac tccaaatgaa cagcagtaga atcattttgt tccacttcat
    64501 atgtctcatg gaaaatttct tgacaaccaa agtcagataa ttgatcaacc tgagttgtta
    64561 aatcaacgtc atttatggtt gtgcgtgcat aaccaataat tttcatggtg attcctttct
    64621 agcagtgatt ttctaactgg atataacagt aaaaatgtag cataaagtac gtcaaaaaga
    64681 tagttttttc gcaaattttc cgctgtcttt ttttattgga tgatcaagca gtttttcttt
    64741 atttacgacg gattgcgtca agaatctcaa cgcctttttc tgagccgaca actactttag
    64801 aaaccatgtt taggaaaagc ccatgttcta ctaccccaac aagttcatct aaataggtag
    64861 ctaagctttc tggctgttcg atgacttcta gatgcagatc aatgatgtaa tgaccaccat
    64921 ctgtggttaa gacttctccg ttttcgtctg tacgcaagac gggttggaat cttttttctt
    64981 caaaaatatg aagtagctgt tgggagccat aagggatcac ttcaactggg agtgggaact
    65041 tcccaagttt atcgactaat ttagaagaat caacgatcca aatcgtttct tttgagtacg
    65101 tagcgactat tttctcgaaa agcaaagcag cgccgccgcc tttgatccct tgaaaatcag
    65161 cactgatttc atcagcaccg tctattgtca aatcgactac ggggacttca tcaatactct
    65221 ttaacggtat tcctaatttt tccgcttgtt cttttgtcgc atttgaagta gtaactcctg
    65281 tgatacgtaa accttcttca cgcatacggc gaccaatctc ttctaccata taataggcgg
    65341 ttgaaccggt cccgagacct acgatcatcc cgtcctttac gaatttcgcg gcttcaatgc
    65401 cagctaattg ttttaaattc atctttgcgt ccaccttttt ttagtttgag catcgtgctt
    65461 tcctcactat tttagcgtga tttacggtaa aaagatacca ttctttttta ttccaataaa
    65521 gctttttcaa aaaaaattgc atctcttgtt gacatgtttt ttcattcgtg atattctaac
    65581 aaaggtgctt tatctacagg tttctgtgaa gaaacgtgct gactgtttat caaagcatat
    65641 ttgataagga tgcagacatt gcatttattt tttatcacaa aaaaagaacc acctggatgt
    65701 gtggaactag acgcaaatcg tgggaaggag gaaacaagga atgcctacaa ttaaccaatt
    65761 agtacgtaaa cctcgtaaat caaaggtgga aaaatctaat tcacctgctt tgaacaaagg
    65821 atataacagc tttaagaaaa ctcaaactaa cgtaaactca cctcaaaaac gtggggtagc
    65881 aactcgtgtg ggtacaatga cacctaaaaa accgaactca gctttacgta aatatgcacg
    65941 tgttcgtttg tcaaacttaa ttgaagttac tgcttatatc ccagggattg gtcataactt
    66001 acaagaacac agtgttgtat tattacgcgg tggtcgtgta aaagacttac caggggtacg
    66061 ttaccatatc gttcgcggtg ctttagatac tgctggtgtt aacgaccgta aacaaagccg
    66121 ttctaaatac ggaactaaaa aacctaaagc ttaattttaa ttattaaaca aatgaaactt
    66181 gcttctacta tatagaagta attactatga acaatatttc ggaaggagga gttacggatg
    66241 ccacgtaaag gtcctgttgc aaaacgtgat gttttaccag atcctattta taactcaaaa
    66301 ttagtaactc gcttgatcaa ccgtgtaatg gttgacggaa aacgcgggat tgcagctaac
    66361 attatctata atgcctttga cttgatcaaa gaatctacag gtaacgatcc attagaagtg
    66421 tttgaacaag caatgaaaaa cgttcaacct gttcttgaag ttaaagcacg tcgtgttggg
    66481 ggttcaaact accaagtacc agttgaagtt cgccctgaac gccgcgttac tctaggtctt
    66541 cgttgggtag taaactacgc tcgcttgcgc ggtgaacaca caatggaaga acgcttagca
    66601 aaagaaatca tggatgctgc aaacaacaca ggtgcttctg ttaaaaaacg tgaagacact
    66661 cataaaatgg ctgatgccaa ccgtgcgttt gctcactatc gctggtaaga ttctctctgt
    66721 ttggtcggct tttataagtc gacctcagat agtgtcctta tttttagcaa ctagatagta
    66781 aagagaggag aaacaaggag aatgaccaga gaattttctt tacaaaacac tcgtaatatc
    66841 ggtatcatgg cccacatcga tgctggtaaa acgactgcta ctgaacgtat cttgtactat
    66901 actggtaaaa tccataaaat tggtgaaact catgaaggag cttcacaaat ggactggatg
    66961 gaacaagaac aagaacgtgg tattacgatc acttctgctg ctactacagc acaatggaag
    67021 ggtcaccgaa tcaacatcat cgacacacca ggacacgtag acttcacagt tgaagttgaa
    67081 cgttcattgc gtgtacttga tggtgctgta actgttcttg atgcacaatc aggtgttgaa
    67141 cctcaaactg aaacagtttg gcgtcaagca acaacttatg gtgtacctcg tatcgtattt
    67201 gcaaacaaaa tggacaagat cggtgctgac ttcttatatt cagtatcaac tttacatgac
    67261 cgtttgcaag caaacgctca cccaatccaa ttaccaattg gtgcggaaga cgacttcaca
    67321 ggaattatcg accttgtaac aatgaaggct gaaatgtata caaacgatct tggaacagag
    67381 atcgaagaaa cagaaattcc tgaagaatac cgcgaattag ctgaagaatg gcgcgaaaaa
    67441 ttggttgaag ctgtagctga aactgatgaa gaacttactt tgaaatactt agaaggtgaa
    67501 gaaatcactg aagctgagtt aaaagaaggt atccgccgcg caacagttaa cgtagaattc
    67561 tacccagtac tatgtggttc agcatttaag aacaaagggg ttcaattact attggacgct
    67621 gttcttgatt acttgccatc accgttagat atcccagcta tcaaagggat tgaccctaaa
    67681 actgatgaag aagtagaacg tcctgcagac gacagcgctc ctttctcagc tttagcattt
    67741 aaagttatga ctgacccatt cgtaggtcgt ttaactttct tccgtgtgta ctctggtgtt
    67801 ttacaatcag gttcatacgt acaaaacgca acaaaaggca aacgtgaacg tgttggtcgt
    67861 atcctacaga tgcatgccaa ctctcgttca gaaatctctg aagtttacgc tggagatatc
    67921 gctgctgctg ttggtttgaa agacacaact actggggaca cactatgtga tgaaaagagt
    67981 ctagttattc ttgaatccat ggaattccca gaaccagtta tccaagtcgc tattgaacct
    68041 aaatcaaaag ctgaccaaga taaaatgggt gtggctttac aaaaactatc tgaagaagat
    68101 cctactttcc gtgctgaaac aaacgtggaa acaggcgaaa caatcatcgc tggtatgggt
    68161 gaacttcact tagatatcat cgttgaccgt atgcgtcgtg aattcaaagt tgaagctaac
    68221 gtaggtgcgc ctcaagtatc ttaccgtgaa actttccgtg ctggcactca agccgaaggt
    68281 aagtttgtac gtcagtctgg tggtaaaggt caatacggtc acgtatggat tgaatttaca
    68341 ccaaatgaag aaggtgctgg tttcgaattt gaaaatgcga tcgtcggtgg ggttgttcct
    68401 cgtgaataca ttccagctgt tgaaactggt ttgaaagatg ctatggaaaa tggtgtctta
    68461 gctggctatc cattagtaga tatcaaagct aaactttacg atggttcata ccatgatgtc
    68521 gattcaaatg aaactgcctt ccgtgttgct gcttctatgg cattacgtgc agcagctaag
    68581 aaagctaatc cagtaatcct tgaaccaatc atggctgtag aagttgttat ccctgaagat
    68641 tatttaggtg atgttatggg tcacgtaact gctcgtcgtg gacgtgttga aggtatggaa
    68701 gctcgcgctg gcggccaaca agttgttcgt gcgatggttc cacttgctga aatgtttggt
    68761 tatgctacaa ctcttcgttc tgctactcaa ggtcgtggta catttacaat gacatttgac
    68821 cactacgaag atgtaccaaa atcagtacaa gaagaaatca ttaagaaaaa cggcggaaaa
    68881 gctgaataat ttcttaaaac cggatagtcc tgcaaagaga ttatccaaag agactatatt
    68941 tttaatatag tttcgtgtaa aataattatc gatgatatgg gcatgtggtg taccttgtgt
    69001 acatcatata cctatcagac aaataaaaaa tatattgtat ttttaggagg acattttaaa
    69061 atggcaaaag aaaaatttga ccgttctaaa ccacacgtta acattggtac tatcggacac
    69121 gttgaccatg gtaaaactac attaacagct gcaatcacaa ctgtactatc taagaaaaac
    69181 ggcggccaag ctatggctta cgatcaaatc gatggtgctc cagaagaacg cgaacgcgga
    69241 atcacaatct caacagctca cgttgagtat gaaacagata cacgccacta cgctcacgtt
    69301 gactgcccag gacacgcgga ttacgttaaa aacatgatca ctggtgctgc tcaaatggac
    69361 ggagctatct tggtagtttc tgctgctgac ggcccaatgc ctcaaactcg tgaacacatc
    69421 ctattgtctc gtcaagttgg tgttccttac atcgttgtat tcttgaacaa agtagacatg
    69481 gttgatgacg aagaattact agaattagtt gaaatggaag ttcgtgacct attaacagaa
    69541 tacgaattcc ctggtgacga tgttcctgta gttgctggat cagctttgaa agctctagaa
    69601 ggcgacgctt catacgaaga aaaaattctt gaattaatgg ctgcagttga cgaatacatc
    69661 ccaactccag aacgtgacaa cgacaaacca ttcatgatgc cagttgaaga cgtgttctca
    69721 attactggac gtggtactgt tgctacaggt cgtgttgaac gtggacaagt tcgcgttggt
    69781 gacgaagttg aagttgttgg tattgctgaa gaaacttcaa aaacaacagt tactggtgtt
    69841 gaaatgttcc gtaaattgtt agactacgct gaagctggag acaacattgg tgctttacta
    69901 cgtggtgttg cacgtgaaga catccaacgt ggacaagttt tagctaaacc aggtacaatc
    69961 acacctcata caaaattctc tgcagaagta tacgtgttga caaaagaaga aggtggacgt
    70021 catactccat tcttcactaa ctaccgtcca caattctact tccgtacaac tgacgtaaca
    70081 ggtgttgttg aattaccaga aggaactgaa atggttatgc ctggcgacaa cgtaacaatg
    70141 gaagttgaat taatccaccc aatcgctatc gaaaacggta ctaaattctc aatccgtgaa
    70201 ggcggacgta cagttggtgc cggtgtcgtt acagaaatca aagcttaatt cacttaagtt
    70261 ttaaagtaaa gcaacattta ttcggacgta atcgctcgga acgaaggtct taggatcttt
    70321 gttccgagct tttttattta ttgcaggatc aggaaaaaag acaggagtat tataaataga
    70381 agaaacacga aataaaagag tcagtatttt ctaaatgaaa ctttatgaaa acaaaatgtt
    70441 ttttacaaga aaaagccttg ctttgtgagt ttatatatat tataatgaca aaggtgcgtt
    70501 tactttagtg aattgcacag acgtaatcag aatgatttcg tcggctaaga aacgagaggt
    70561 tgcgacacgc ccggacgctt tgccacgaac gagcgtgacg gaaattttcg tggagctatg
    70621 tctacttttc aaaataggcg aaggagggaa caagatggca aaacaaaaaa ttcgtatccg
    70681 tttaaaagcg tatgaacacc gtattttaga tcaatcagcg gataaaatcg tggaaactgc
    70741 aaaaagaact ggagctagcg tgtctggtcc aattccatta ccaactgaac gcagtcttta
    70801 cacaatcatc cgtgcgactc ataaatacaa agattcacgc gaacaattcg aaatgcgtac
    70861 acacaaacgt cttatcgaca ttgtgaaccc aacaccaaaa actgttgatg ctttgatgaa
    70921 gctagactta ccatctggtg taaacatcga aatcaaatta taaaactaaa acaaaaataa
    70981 tggaggtgta ctcatgacca aaggaatctt agggaaaaaa gtgggaatga cacaaatctt
    71041 cactgaatct ggtgaattaa ttccagtaac tgttgtagaa gctactccaa acgtagtact
    71101 acaagtgaaa acaatggaaa cggatggcta cgaagctatt caagttggtt accaagatat
    71161 gcgtgaagtt ttatcaaaca aacctgcgaa aggtcatgtt gcaaaagcaa acacggctcc
    71221 taagcgcttc attcgtgaat tcaaaaatgt tgagctagga gaatatgaag taggaaaaga
    71281 aattacagta gatgttttcc aagcaggaga cattattgat gtaacaggta ctacgaaagg
    71341 taaaggattc caaggggtta tcaaacgcca cggacaaagc cgcggaccaa tggctcacgg
    71401 ttctcgttac catcgtcgtc ctgggtcaat gggtccagtt gcacctaacc gtgtatttaa
    71461 aaacaaacgt cttgctggcc gtatgggtgg caaccgcgta actatccaaa acttggaagt
    71521 tgtacgtgtc gatgcagaaa gaaatgttat cttgatcaaa ggtaatgttc ctggagctaa
    71581 aaaatcttta attactatca aatcagctgt gaaagctaaa taattgtagg aagaaaggag
    71641 gaactaagga atgccgaatg tagcattatt caaacaagat ggaagccaaa acggtgaaat
    71701 cacacttaac gaagaaatct tcggaattga acctaatgaa agtgttgttt acgatgcaat
    71761 cgtaatgcaa cgtgcgtcat taagacaagg aacacacgcg gttaaaaacc gtagcgctgt
    71821 tcgcggcggc ggacgtaaac catggcgtca aaaaggaaca ggtcgtgcac gtcaaggatc
    71881 tatccgctca ccacaatggc gtggaggtgg cgtagtcttt ggaccaacac cacgttctta
    71941 cagctacaaa cttcctaaaa aagttcgtcg tttagcaatg aaatctgtat tgtcagaaaa
    72001 agttgctgaa aacaacttgg tagcaatcga aggcttgaac ttcgacgcac caaaaacaaa
    72061 agaattcaaa caagttcttg ctaacttatc tatcgactct aaagtattgg ttgttctaga
    72121 aaaaggtaac gactttgctg ctttatcagc acgtaactta ccaaacgttt ctgtagtaac
    72181 ttctgataat gtgagtgtgc tagacgttgt atcaaataca aaagtgttag caacacaaac
    72241 tgctcttact caaattgagg aggtgcttgc ataatgaact tactagacgt aatcaaacgc
    72301 ccagtgatca ctgaaaaatc aatgcttgcc atggatgaca agaaatacac ttttgaagtg
    72361 gacactcgcg caaacaaaac tttagtaaaa caagcggtag aagctgcttt tgacgttaaa
    72421 gtcaaaaacg tgaacatcgt gaacgtacgt gcgaaattca aacgtatggg caaatatgca
    72481 ggatatacaa aaaaacgtcg caaagcgatc gttacattga ctgaagattc aaaagaaatc
    72541 caattattcg aagctgctga ataagcacta atagataact cattaaatta ggagggaaaa
    72601 acgtggcgat taaaaagtac aaacctacct caaatggtcg tcgtaacatg acaggttctg
    72661 attttgctga aatcacaaca tcaacacctg aaaaatcatt gttacaacca ttgaaaaacc
    72721 atgctggacg taacaacaac ggccgcatca ctgtacgtca tcaaggtggc ggacacaaac
    72781 gccaatatcg cgtgatcgac ttcaaacgta acaaagataa cgttgttgca actgttcaaa
    72841 cgatcgaata tgatccaaac cgttcagcta acatcgcgtt agtacactat gaagatggag
    72901 tgaaagctta catcttagca cctaaaggac tagaagtggg tatgaaactt gtttcaggtc
    72961 cagaagcaga tatcaaagtc ggaaatgctc ttccattaga aaacattcca gttggtactg
    73021 ttatccacaa cattgaaatg aaacctggta aaggtggaca attgatccgt tctgctggta
    73081 caagtgctca agtacttggt aaagaaggca aatacgtatt gatccgcttg aactctggtg
    73141 aagttcgtat gatcttagct gcatgccgtg ctacaatcgg ttctgtaggt aacgaacaac
    73201 acgaattaat caacatcggt aaagctggac gctctcgttg gatgcgtaaa cgcccaactg
    73261 tacgtggtag cgtaatgaac cctaatgatc acccacacgg tggtggtgaa ggtaaagctc
    73321 ctatcggacg taaagcacca gtttctcctt ggggtcaacc agctcttggt tacaaaactc
    73381 gtaacaaaaa agctaaatca gacaaactta ttgttcgtcg tcgcaaaaat aaataattac
    73441 tttgaccatg tgtcgcacat tttgagagga ggttcaccat gggtcgtagt ttaaagaaag
    73501 gaccttttgt cgatgagcat ttaatgaaaa aagttgaagc tcaagcaggg gttgaaaaga
    73561 aaaaagttat caaaacttgg tcacgccgtt caacagtttt cccaagtttt gttggatata
    73621 ccatcgcagt ttatgatgga cgtaaacatg taccagttta catccaagaa gacatggtag
    73681 gacacaaatt aggtgaattt gcacctacaa gaacttatcg tggacatgct gctgacgata
    73741 agaaaacgaa acgctaattt gaggggagga taaatccaaa tggcagaaca aatcacatca
    73801 gctaaagcaa ctgcaaaaac agttcgcact tcacctcgaa aagcccgttt agtaattgac
    73861 cttatcagag gtaaaagtgt cgcagatgca atttcaatct tgaaattcac accaaacaaa
    73921 tctgctggaa tcattgaaaa agtattgatg tcagcagttg cgaatgcaga aaataacttt
    73981 gacttagatg ttgaaaactt ggtagtaagc gaagcttttg ttaacgaagg acctacaatg
    74041 aaacgtttcc gtcctcgtgc aaaaggatca gcttctccaa tcaacaaacg tacaagtcat
    74101 atcacggtag tcgtatcaga aaaataagga gggataatca gtgggtcaaa aagtacatcc
    74161 aattggaatg cgtgtaggca tcatccgcga ctgggatgct aaatggtatg ctgaaaaaga
    74221 gtatgctgag ttcttacacg aagatttaag aatccgtaaa tttatttcaa ctaaacttgc
    74281 tgatgctgct gtatcaacag ttgaaatcga acgcgcaaca ggtcgcgtaa acatttcaat
    74341 tcacacagct aaaccaggta tggttattgg taaaggcggt tctgaagtcg aaagcctaag
    74401 aaaagaatta aacaaattaa ctggtaaaag aatccatatc aatatcgtgg aaatcaaaaa
    74461 accagatcta gatgcaaaat tagtaggtga aggaatcgca cgtcaattag aaaaccgtgt
    74521 tgctttccgt cgcgctcaaa aacaagccat ccaacgctca atgcgtgctg gcgctcaagg
    74581 gatcaaaact caagtatctg gtcgtctaaa cggagcagat atcgctcgtt cagaaggata
    74641 ctcagaagga actgttcctc ttcatacttt acgtgcggac attgattacg catgggaaga
    74701 agcagataca acatacggaa aactaggagt taaagtgtgg atctatcgtg gagaaattct
    74761 tccaactaaa aaaaacactg agaaaggagg gaaataatca tgttagtacc taaacgtgta
    74821 aaacaccgtc gtgaattccg cggaaaaatg cgcggggaag ctaaaggcgg aaaagaagta
    74881 gcattcggtg aatacggttt gcaagctgtt gattcacatt ggatcacaaa ccgccaaatc
    74941 gaagctgctc gtatcgcaat gactcgttac atgaaacgtg gtgggaaagt atggattaaa
    75001 attttccctc acaaatctta tactgccaaa gcaattgggg tacgtatggg ttctggtaaa
    75061 ggggcacctg aaggatgggt tgcaccagta aaacgtggta aaatcatgtt tgaaatcgca
    75121 ggcgttcctg aagaagtagc tcgtgaagcg ttacgtctag cttctcacaa attaccaatg
    75181 aaaactaaga tcgtaaaacg tgaggaaatg ggtggtgaat cgaatgaagg ttaaagaaat
    75241 cagagaatta accactgccg aaatgcttga tcaagaaaaa caattaaaag aagaattgtt
    75301 taatcttaga ttccaattag caacaggtca attagaaaac actgcacgta ttaaagaagt
    75361 acgtaaatcg attgcacgca tcaaaactgt gttgcgtgaa caagctaagt aattatggaa
    75421 ggaggccatt aagcgtatga ctgaaggaag aaatcaacgc aaagtttatc aaggtcgcgt
    75481 ggtttcagac aaaatggata aaacaattac cgttgctgtc gaaacaaaga aaaaccaccc
    75541 tatctatggc aaacgcatga actattctaa gaaatacaaa gtgcatgatg aaaacaacac
    75601 agcaaaagtt ggcgacatcg tgagaattat ggaaactcgt ccattatcag ctacaaaacg
    75661 tttccgtttg ttggaagtag tcgaagaagc agttattatc taataacacg agactttcct
    75721 atatagattg aatgcaaaat ctgaaaggag gatacacaac gtgatccaag cagaaagtcg
    75781 tttaaaagtc gctgataact caggcgcacg tgaaattttg acgatcaaag tccttggtgg
    75841 atctggtcgt aaaactgcta acatcggtga tgtgatcgtt gctacggtta aacaagcaac
    75901 gccaggtggg gttgtcaaaa aaggtgacgt cgttaaagcc gttatcgttc gaacaaaatc
    75961 aggagctcgt cgtacagacg gttcatatat taaatttgat gaaaatgctg cagtgattat
    76021 tcgtgatgat aaaagccctc gtggaacacg tatctttggg ccagttgcac gtgaactacg
    76081 tgaaaacaac ttcatgaaga tcgtttcact agcaccagaa gttttataat cttgagacac
    76141 ttatcaaagg aggtgcgaaa cagttatgtt tgttaaaaaa ggcgataaag ttaaagttat
    76201 cactggaaaa gacaaaaaca aagaaggcgt tgtactagca gcgttcccga aaaaagataa
    76261 agttattgtc gaaggtgtaa atgtcgttaa aaaacaccaa aaaccttctc aagctgctcc
    76321 tcaaggtgga attgttgaga tggaagcgcc aattcatgtt tctaacgtga tggtggttga
    76381 ctctactggt gtagctggcc gagttggcta caaagaagta gacggcaaaa aagtccgtgt
    76441 ttctaaaaaa accggtgaag ttttagataa ataaaagttt aaggaaggag ggtcttactg
    76501 aatgaaccgc ctaaaagaaa aatatcttaa agaagtaact ccatcattga tggaaaaatt
    76561 taactatagc tctgttatgc aaacacctaa agttgaaaaa atcgtcatca acatgggtgt
    76621 tggtgatgcg gtatcaaacg ctaaaaactt agataaagca gttgaagaat taactttgat
    76681 cactggtcaa aaaccaatga ttacaaaagc taaaaaatca atcgctggat tccgtttacg
    76741 tgaaggaatg ccaattggtg caaaagttac attgcgcgga gaaagaatgt acgaattctt
    76801 agacaaattg gtttctgttt cactaccacg tgtacgtgac ttccatggtg taagtaaaaa
    76861 agcctttgac ggtcgtggaa actatacttt aggtattaaa gaacaattga tcttcccaga
    76921 agtagattat gatttagtag ataaagtacg tggtatggac atcgttattg taacaacagc
    76981 aaactctgat gaagaatctc gtgagttgtt gacacaatta ggcatgccat tccaaaaata
    77041 attaaaggag gcgaactacg tggctaaaaa atcaatgatt gctaaaaaca aacgtcctgc
    77101 aaaattttca acacaagctt atactcgttg cgaacgttgc ggacgtccac attcagttta
    77161 tcgtaagttc catctttgcc gtatttgctt ccgcgaactt gcctataaag gtcaaattcc
    77221 cggcgtgaag aaagctagct ggtaaaaagt aaattcgcat aagaaggagg taaaagatca
    77281 atggtcatga cagatccaat tgcagatttt ctaactcgta tccgtaacgc aaacatggtt
    77341 aaacatgagt ctttagaagt acctgcatca aaaattaaac gtgacatcgc tgaaatcttg
    77401 aaacgtgaag gtttcgttcg tgatgttgaa tacatcgaag atgacaaaca aggcgtgatc
    77461 cgtgttttcc taaaatttgg taaaaacggc gaacgtgtta tcacaaactt aaaacgtatc
    77521 tctaaaccag gtttgcgtgc ttatgtcaaa gctgacgaag taccaaaagt attgaacggt
    77581 ttaggtatcg caatcatttc gacttctgaa ggtgttgtca ctgataaaga agctcgtgaa
    77641 aaaaatatcg gcggcgaagt tatcgcttac gtatggtaat caagtagaat ctacaaggag
    77701 gtgtctttaa gtgagccgta tcggaaataa agtcgttgtt atccctgaag gagtaacagt
    77761 tactcaagac ggaaacaacg ttacagttaa aggaccaaaa ggtgaattga ctcgtacttt
    77821 ttcagcagat atcaaaatga atatcgaagg aaacgaagta actttcactc gtccaaacga
    77881 cagtaaagaa atgaaaacaa ttcatggaac aactcgtgcg aacttcaaca acatggttgt
    77941 aggtgtcagc gaaggtttcc aaaaagcgtt agaactaatc ggggttgggt accgtgcaca
    78001 attacaagga tcaaaacttg tattgaacgt tggttactca catccagtag aaatcacacc
    78061 accagctgga gtaactgttg aagtaccagc taacacacaa gtaattgtta aaggtgcgaa
    78121 caaagaagaa gttggcgaat tagctgcaaa cattcgtgga actcgtcctc cagaacctta
    78181 taaaggtaaa ggtattcgtt atgttggcga atatgtacgc cgtaaagaag gtaaaactgg
    78241 taaataatcg tttagaaaaa ttgcatagaa gccagcagca ggaaaaaggc atttggctga
    78301 agtttacctt caaaaaaata catttttact tgtgccgcag cttctatttt tcgaaacgta
    78361 tttactgctt gaaatagtag tacaataaaa ataaagaggt gacaattgtg attacaaaac
    78421 cagataagaa caaaacacgt caaaagagac atcgtcgtgt acgtaacaat atctctggta
    78481 ctgctgagcg cccacgcttg aacgtttttc gttctaacaa aaacatctac gctcaaatta
    78541 ttgatgacgt agcgggtgta acgctagcaa gtgcctctac cttggataaa gaaatttcag
    78601 gtggaacaaa aacagaagca gcacaagctg tcggtaaact agttgctgaa cgtgcagctg
    78661 aaaaaggcat taaagtagta gtctttgacc gtggtggata cctttaccat ggccgtgtgc
    78721 aagctttagc tgaagctgct cgcgaaaatg gactagaatt ttagaagaag gaggaatacc
    78781 attcatggtt tatatcgatc caaaacattt ggaattagaa gaccgcgttg ttgcaattaa
    78841 ccgtgtaaca aaagttgtta aaggtggacg tcgtctacgt tttgctgctt tagttgttgt
    78901 cggtgacaaa aacggacacg tagggtttgg tacaggtaaa gctcaagaag ttcctgaagc
    78961 aatccgtaaa gcaattgaag atgcgaagaa aaacttagtt gaagtaccta tggttggttc
    79021 aacaatccca cacgaagtaa tcggtgcttt tagtggtggt agaatcctaa tgaaacctgc
    79081 tgtagaaggt tctggggttg ctgctggtgg accagttcgt gccgtattag aattagctgg
    79141 ggtagcagat atcacttcta aatctttagg ctcaaataca ccaatcaacg ttgttcgcgc
    79201 aacagttgaa ggtttgaaac aattgaaacg tgcagaagaa gttgcagaac ttcgcggcaa
    79261 atcagttgaa gaattaatcg gataaggagg acaacaataa tggctgaatt aaaagttact
    79321 ttaaaacgca gtattatcgg acgtcctcaa aaccaacgcg atacagttaa agcgttaggt
    79381 cttacaaaga ttaacagttc agtggttaag ccttctaatg aagcaattaa aggcatgatc
    79441 aatactgttt ctcacctagt ggacgttgaa gaaatttaat ttagaaaaat cataactaga
    79501 acattaagga ggtgccaaac ctatgaaact tcatgaatta aaacctgctg aaggttcacg
    79561 ccaagtacgt aaccgtgttg gtcgtggtac ttcatctggt aacggaaaaa ctgccggacg
    79621 cggacaaaaa ggacaaaaag ctcgttcagg cggcggtgtg cgtttaggat ttgaaggggg
    79681 acaaacacca ttgttccgtc gtttaccaaa acgaggattc acaaacgtga accgtaaaga
    79741 ctatgcagtc attaatcttg atgtattgaa ccgctttgaa gacggagctg aagtaactcc
    79801 tgttgcttta gttgaagctg gaatcgtgaa aaacgaaaaa gctggaatca aagtattagc
    79861 taatggggaa ctaaacaaga aattaactgt gaaagcagca aaattctcta aagcagctca
    79921 agaagcaatt gaagcggctg gtggatcaat cgaggtgatc taatgtttag actattaaaa
    79981 gatgctttta aagtaaaaga cattagatcg aaaatcctat ttactgtatt tgtgttgttt
    80041 gtatttcgcc taggtgcaca tattactgta ccaggcgtaa atgctgcttc attgcaaaac
    80101 ctttcttctt tgccattttt caacatgttg aacttggtaa gtggtagtgc gatgcaaaac
    80161 ttttccattt tctcaatggg ggtttcacca tacattactg cttctatcgt cattcagctt
    80221 cttcaaatgg acatcgtgcc tcgatttgtt gaatggtcga aacaagggga agttggtcgt
    80281 aaaaaactga atcaagcgac tcgatatctg acattagtat tggcatttat ccaatctgtc
    80341 ggtatcactg ctggattcaa tcaatacgct caattaggtt tcgtgaataa tcctaacgta
    80401 gcaacttacg taacgatcgg tttgattcta acagccggta cgatgtttgt tacttggcta
    80461 ggagaacaga tcacagaaaa aggtatcgga aatggcgtat caatgatcat ttttgcaggt
    80521 atcatttcta gattgcctga aagtatcaga gaaatttatg aagattactt tataaatatt
    80581 gatccttcag acatatggaa atctgctatt tttgtggcca ttttactagt agcggtcttg
    80641 ttgatcgtga cattcgtaac atttttccaa caagctgaac gcaagatccc gatccaatat
    80701 acgaaacgcg tagctggcgc gcctacaagc agctatctgc cgttgaaagt aaatgcagct
    80761 ggagttattc cagttatctt tgctagttcg tttattgcta cgccaaatgc tgttttacaa
    80821 gcattgagcg gtagattcgg ttctgaaaac tggtacaaag tgatgatgga gatctttaac
    80881 tataatacag cacctggtgc tacgatttat acgattctga tcgttgcctt cactttcttc
    80941 tacgcctttg ttcaagtaaa ccctgagaaa ttagcggaaa acttgcaaaa gcaaggaagt
    81001 tatataccaa gcgtacgccc tggtaagggg actgaagagt atgtctcaag attactgatg
    81061 cgtttaagta cagttggtgc agtcttcctt ggtttagtgg cattgcttcc aatcattgct
    81121 caaatggttt gggatcttcc acaatcaatc ggattaggcg gtacaagctt actgatcgtt
    81181 atcggtgtag ctttagaaac tgcgaaacag ttagaaggct taatgctgaa acgtaaatat
    81241 gttggattca ttgagtaaga aagcgtgttg aggtttcccc tcaacacacg ttctcacaca
    81301 tttattagga gggaaaacaa tgaacctcat tttaatgggg ctgccaggcg caggtaaagg
    81361 aacacaagct gaaaaaatca ttgatgctta tggtattccg cacatctcaa caggagatat
    81421 gttccgcgca gcgatgcaaa acgaaacagc tcttggcctg gaagcaaagt cttatatgga
    81481 taaaggtgca ttagttcctg atgaagtaac aaatggaatc gtgaaagagc gactagctga
    81541 accagataca gagaaaggct tcttattaga tggctttcca cgtacgctag atcaagcaaa
    81601 agctctggac gcaatgctaa aagatttgaa taaaaaaatt gatgctgtca tcgatatcca
    81661 tgttggtgaa gaaatcttgg tcgaacgtct agccggccga tttatctgca gcaattgtgg
    81721 agcaacttac cataaaattt tcaaccctac aaaagttgaa gacacatgtg atcgttgcgg
    81781 tgggcatgaa ttctatcaaa gagaagatga taaacctgag acggttaaaa atcgtctggc
    81841 tatcaacatc aaaaatagtg aaccaatctt ggcttattat aaagaacaag gtttgctaaa
    81901 cactattgat ggtgctcgtg aaatcgatgc tgtatttgca gatgtacaaa aaatcattga
    81961 aaaatagcac gattgcccgt agccgacttg cattatgcag ttactcttgt caagttcaat
    82021 aaattatgat agaatatgtc agtccgactt ctagagaatc ctctagatga tccattttga
    82081 gaattttgag gtgggaactg cagtttccgc cattttatcg tgtgaaaatg cgaaacaagt
    82141 acaaggaggt actgtgcgtg gcaaaagaag atatgattga agtcgaaggt acagtcgtcg
    82201 aaactttgcc gaatgcaatg tttaaagttg aactagaaaa cggacaccaa gttcttgcta
    82261 ctgtttcagg taaaattcgt atgcattaca tccgtatctt acctggtgac aaagtaacgg
    82321 ttgaattgtc tccatacgat cttaaccgtg gccgtattac ttatcgcttt aaataattgt
    82381 actccgtaaa actacaggag gtattatcat gaaagtaaga ccatcagtaa aaccaatgtg
    82441 cgaacattgt aaagtaattc gtcgtaaagg acgcgttatg gtgatttgcc cagcaaatcc
    82501 aaaacataaa caacgtcaag gataattgga ggtgctataa atatggctcg tattgcagga
    82561 gtagatattc ctcgtgataa acgtgtagta gtttcactta cttatatcta tggtattggt
    82621 aacactactg ctaaaaagat cttagctgat gctggtgtat ctgaagatgt tcgcgttcgt
    82681 gaattaacga atgaacaaac agatgctatc cgtgcagaag tagataaatt aaaagttgaa
    82741 ggggatcttc gtcgtgaagt gaacttgaac atcaaacgtt tgatggaaat cggttcttac
    82801 cgtggaatcc gtcatcgccg tggattgcct gttcgtggac aaaacacgaa aaacaatgca
    82861 cgtactcgta aaggcccagc tcgcgctatc gctggcaaga aaaaataatt cttaagtgaa
    82921 ggaggttaaa acttcatggc agcaaaaaaa gtgaatcgta aacgccgtgt gaagaagaat
    82981 atagaagcag gtattgcaca tatccattct acattcaata acactatcat catgatcact
    83041 gatactcacg gaaatgcatt agcgtggtca tcagctggtt cattaggttt caaaggaagc
    83101 aaaaaatcaa ctccttttgc cgctcaaatg gcagcagaaa ctgctacaaa agcagcaatg
    83161 gaacacggat taaagactgt tgaagtaaca gttaaaggac ctggttctgg acgtgaagca
    83221 gcaattcgtt cattacaagc tacaggttta gaagtgactg caattcgtga cgtgactcca
    83281 gttcctcata atggtgcccg ccctccaaaa cgccgtcgtg tttaatgagt gccgctcatt
    83341 ttgagtttta tcagtaacgt cattgaacaa gacacttttc gttttgaaag gggtaaagat
    83401 aagaatgatt gagttcgaaa aaccaagaat cgcaaaaatt gatgaagaaa aagattatgg
    83461 caagttcatc gttgaacctc ttgaaagagg gtatgggact actttaggga attccctacg
    83521 tcgtatttta ttatcttctt tgccaggtgc tgccatcact aatattcaaa tcgatggtgt
    83581 actgcatgaa ttctctacca tcaaaggtgt tagagaagac gtcactcaaa tcatcttgaa
    83641 cattaaaggc ttagcgctga aaatgtatgg ccaagaagaa aaaacccttg aaatcgatat
    83701 taccggacct gctacagtaa ctgctggcga tattatcgtt gatagtgatg tagaaattct
    83761 taacaaagat atgtacatct gtagtgtctc tgaaggagct acgttccatg ctcgcttaac
    83821 agtgaaacct ggacgtggtt atgttcaagc agatgaaaat aaaaaagaag atatgccaat
    83881 tggcgttctt ccagtcgatt caatctacac acctgttcgt cgtgtgaact atcaagttga
    83941 gaacacacgt gttggacacc gtgaagattt tgataaattg acgatggaga tttggacaga
    84001 tggttcaatt gaaccgttgg aagcaatgag tttgtctgcg aaaatcatga ctgaacattt
    84061 ggatattttt gtgaacttaa ctgatgaagc aaaaaatgct gaaatcatgg tcgaaaaaga
    84121 agaaacacaa aaagaaaaaa tgttggaaat gacgatcgaa gagttagact tgtctgttcg
    84181 ctcttacaat tgtttgaaac gtgcaggaat caatactgta caagaactta caaataaatc
    84241 tgagcctgaa atgatcaaag tccgtaactt aggacgtaaa tcattagaag aagttaaagc
    84301 aaaattgcac gacttaggtt taggtttacg taaagaagat taaaaccttt tacgaaggag
    84361 ggaaaccaac gtgagttatc gtaaactagg acgcacatct agccaacgta aagcgatgtt
    84421 gcgtgattta acaactgatt tattaatcaa cgaacgtatt gtgactactg aagctcgtgc
    84481 gaaagaagtt cgctcaactg cagaaaaaat gatcacttta ggtaaacgcg gagatttgca
    84541 tgcacgtcgt caagctgcgg ctttcgtacg taatgaagtt gccagcgtgc gtgaagaaaa
    84601 tgaggacatc gtcattgaat cagctttaca aaaactgttc aacgatattg cacctcgtta
    84661 cgcagaacgt caaggcggat acacacgcat tttgaagaca gaaccaagac gcggtgatgg
    84721 tgcaccaatg gttgtcttag aacttgtcta aaatcacact aataacatca ctttatagat
    84781 gattctttta gagtgttatg atgttggaag atatttttcc gagtctagct cagcgctgct
    84841 cctcaagcga atatcgcttg gggagtaagc actcatcata aagtgttttt ttataccttc
    84901 aattacctgt catgacagat atgtttgaag gcataaaaaa acattttaag cgagaaataa
    84961 ttgaaaattt tgtctttttt tgatagtgtt agtaggaact ttaggatgaa gaaggagtaa
    85021 tcatggagcc aattattgaa ttagaaaaga taaattataa ataccagcca gatgatcttc
    85081 gccccgcatt gaaagatgtc tcctttacaa ttgataaagg tgagtggatc gctattattg
    85141 gacacaatgg ttcaggaaaa tcgacacttg ccaaaacgat caatggattg cttctgccag
    85201 aatcagggat cgtgaaagtg ggaaatcaaa tattggatga agaaaatatt tggacgatcc
    85261 gacagatggt tggaatggtt tttcaaaatc cagacaatca gtttgttggt tcgacagtag
    85321 aagatgacgt tgcttttggt cttgaaaatc aagggattcc cagagaagaa atgctagtgc
    85381 gtgtgaaaga tgcacttgag aaagttagaa tggctgagtt tgcttcacgc gagcctgctc
    85441 gtttatcagg agggcaaaaa caacgtgttg ccattgccgg cgtggttgcc ttacgacctg
    85501 atatcattat tttagatgaa gcaaccagta tgctagatcc agaaggtcgt gaagaagtga
    85561 tctctacgat caagaagatc aaagaagaaa gtcaattgac cgttatatct atcactcatg
    85621 atattgatga agcagctaat gccaatcgga tactagtgat gagacaaggc gaacttgtcc
    85681 gtgaaggtac accaaaagaa attttttctg ctggtcctga actgatcgac ttaggtctag
    85741 atctaccatt tcctgaaaaa ctgaagagcg cactgaaaga acgtggggtt gatgtgccca
    85801 gtgaatatat gacagaagaa aggatggtgg attggttatg gacatccgtt ttgaacaagt
    85861 agacttcact tatcagccga atacaccatt tgaacaaaga gccttatttg acatcaatat
    85921 gacgatcaaa gaaaacagtt atactgcatt agtagggcat accggaagcg ggaaatcaac
    85981 cttacttcag catttgaatg cgcttgttaa gccaacaagc ggtacagtcc atattggaga
    86041 acgagatatt cagccggata cggataataa gaatttaaag cccatccgaa aaaaagttgg
    86101 catcgtcttt cagtttccag aagcacagct attcgaagaa acggtagcaa aagacattgc
    86161 tttcggtcct aaaaactttg gtgtcagcga agaagaagca ctagtcctag caaaagaaac
    86221 attagaacaa gttgggctgg atgaaagcta tttggaacgt tcgccatttg aactttcagg
    86281 agggcaaatg cgtagagtag caatcgctgg tgtgcttgcc atgaggccgg aagtacttgt
    86341 attggatgaa ccaacggcag gacttgatcc ccagggcaga aaagaaatga tggagatgtt
    86401 ttggcgtctt cataaggaac agcagatcac tattgtatta gttacgcatt taatggatga
    86461 tgtagccaat tttgcagatt atgtctatgt gttggaaaag ggacgaatcg ttaatagcgg
    86521 ggagccgcaa gaggtctttc aaaacattga atggctaaaa gaaaaacaac taggcgtacc
    86581 tactgccacc gagtttgcag aagaattaat ggctaaaggg atgaactttg ctaccttgcc
    86641 tttgacagct gaagaattag cagacgctat cgtccattat gctggaggaa atgcccatga
    86701 tgaataaatt gatatttggt cgttatatgc ctggagattc cttgatccat cgattggatc
    86761 cccgagctaa attattagcc agtttttatt ttatcggaat cattttttta gcaaataatt
    86821 gggaaacgta ccttttgttg gcatttttca cattactttc tgtcttcttg tcaaaagtag
    86881 atttgaaatt ttttatccga ggcattcgcc cattgatctg gctaatcctc ttcactgtag
    86941 ctttgcaggt cttgtttaca agtggcggag aaacttattg gagttggggt gttttccata
    87001 tcactgaatt tggtgtgatg aacggcctct ttattttctg tcgattcgtg ttgatcattt
    87061 ttatgtcgac tctactcacg cttactacac cgcctttgga attatcggat gcgattgagt
    87121 acttgcttcg tccattgaaa gccgtacggt tcccagtcca cgaaatttca ttgatgctgt
    87181 cgattgctct tcgttttgtg cctacattga tggacgaaac agaaaagatc atgaacgctc
    87241 agcgcgctcg cggtgttgat tttggtgaag gaaacctagt tcagaaaatg aaagcagtca
    87301 ttcctttgct gattccttta tttgtcagca gcttcaaccg tgcggaagat cttgcgactg
    87361 ctatggaagc aagaggctac aaaggtgggg aaggaagaac gaaatatcgt gtattgcatt
    87421 ggcataatag agacacgatg gttatcattg cttttgtatt attaactgtg ctactgatct
    87481 ttttaagagg ataaacgttc agtgggccgc tatctattct tttcttgctg atctgtttgc
    87541 aagaaaggat gcaagcagtg tatgacaaga aatattaggg tctgtggcag actaaggtca
    87601 caggcctctt tcttttatct gaaaagaaag aacgaaaaaa ttttatagaa aaatcattat
    87661 tccagataac cttttaggaa caaaggagag aaaaacatgg tacgttacaa agcaatcatt
    87721 gcgtacgacg gaacaaattt taatggattc caaaaacagc caaatgggcg tactgttcaa
    87781 gaagaagtag aaaaaacatt acaaaaaatg gcaaatggaa aagaaatcac ggtctttggt
    87841 tcgggaagga cagatgccgg agtacatgcg atcgggcaag taatccattt tgattatcca
    87901 gaggagcgtc cgttagaacg aatgcgtttc gcgctagata cccagtcacc agaggatatt
    87961 gctgtaagac aagtagaaat tgtttcagaa gacttccacg caagatattt ggtcaaagaa
    88021 aagacgtatc aatttcgagt ggatataggg aaaccacgca gtccttttcg acgccattat
    88081 gcaagttatt ttccttaccc acttgatttg gaaaaaattc agcgggcgct tcctgattta
    88141 ttagggactc acgatttcac ctctttttgt gcatcaggaa gctcgataga ggataaaata
    88201 cgtacgatct acgaggctaa gatggaggta aatgaaacaa aagacgaatt gttgtttaca
    88261 tttaggggaa atggcttctt gtataagatg atacggatct tagtaggaac gcttttgaaa
    88321 attggcaatg gccgattgcc tgaagatagt atcccagata ttattgcgaa aaaagatcgt
    88381 aatgcagcag gacctacagc acaccctgaa ggactttatt tgtatgaagt gaaatatgaa
    88441 taagaggtta tgatagaagt ggtcagcttc aagaaataag aaggtattta cgaaaattac
    88501 ttctcaaaat tttgcaaaat ttcggcttat tttcgaagaa gctacttctg gaacaccgtt
    88561 taagaaagag gtcgtgagcc tgtcatttaa ctctgagtca caaagagcaa tttcaaaaaa
    88621 cagcttctca tctttgatga atatcgtgac ttgtggacga ggcgttgata agtgaatcat
    88681 ctttttgtta cctatttttt ctgtaaccaa aaaacgatgg aacgttgttt tgattgccct
    88741 tggtgcggac agtctgaaca ggttccatcg tttctttatt ttctacgtct tcttctgtgt
    88801 gtgtttcgtg gttgttcttc tattgctgga tcaatcgtgc cataaaaggg gcgattgcgg
    88861 tcaaggtacc agacataaag aataaacaat gcaatacata ggacaaaaag gattgcacct
    88921 atcgtaaatc cttcaggcaa gtaactgaaa gtgacagtat gtttacctgc tggaactttt
    88981 atcatcaaga atgcgtcttt gaaattgctg accttgactg gtttcccatc aattttagct
    89041 ttccatcctt tgtcataagg aatagttgtc accaacatgg aatcttcagc ggtatttaca
    89101 gtcccagaag cttttctgcc agtggcttcc atttcgacac ctttttcttt gatctgattc
    89161 attgcggctt gataggctac aacatctaga ccaacgactt taggctccat gaaacttatt
    89221 tctttcgtcc cataaaaact tgcagtaaat gtcactgttg tctcttgagg ataatagcca
    89281 agatcatagt attgaccaga aatgttgatt tgcgtttttc gcgatgtacc attgacagtg
    89341 atcgtcgcac tagaactttc taattgcgca aaattggttg ggaacaaact taagtaagct
    89401 tgtgtatttg caggcacatg gacttcccaa gtgagctctt ttggctggtt atctgctgtt
    89461 tctgagtaag tgacgccagt cgttgtcttt gtgatcgtcg tattcaactg attcttcaaa
    89521 gtaggtgtat agaatgtaaa atactgttca tttagaccag acaatgtatt gatcaagttt
    89581 gtctgactgg tcaaattatc tgtcactggc tgctcaacat cattaacgga caacggtgca
    89641 gtaaatgcta gtggcaatgc attgacattc tgatacagtg tatagtcgcc gctttgacca
    89701 gcttggcgga agccatattt actgaacgtg ctttcgtttt tagaaatgtt atatttgatt
    89761 cctgtaaacc catccatcag caaagtatta ttgttataac ggatattcaa atttgtccct
    89821 cttgaacgga aacctaattt atccaggtaa gaggaagaat tacgatttct tatagaagaa
    89881 aacaaactga taccactgta accatagttg atcgaatcgt ttgcagatac tggatccaga
    89941 ttttccaagc ggtaaaacga gtcggaatct ttttttgttt catttacaag agctttcaag
    90001 tcaggataag gatcagtata taaactgcgg gaagcataat tccaatcatc aagaatgcca
    90061 tggatcatac tgttcgtatt gaccagtgct tcagcagaca tgatcaataa taacaatata
    90121 ctcagatgat tgaatgaaag ttttttatgc tgataaaatc ccacagcaaa agcataaatc
    90181 cctaagaaaa ccactgtcaa tacaaaggaa gtcatcgtca cataggtgta gcttccttca
    90241 ggtttgatgc cccatgccac cgcaaagaga gcagctacga ccaaaatgat tcctaacaac
    90301 agcccacgat cgtcttgttc tatcttttcc catccttttc ctgcaagcag gagcactaag
    90361 aaagagaaca gataggcata acggaataaa aacatattcg gtgcatgcat accatgccag
    90421 aacaaattca atggaacaag ataaaaactt gcgataagta tggcgaaaag actgccgtac
    90481 aaaaatttat ttttcaacgg tactttccga ctggcaaaat aaaacagaca gaggactaat
    90541 ggtagcagac ctgcgtaaac gaacggaatc gatccgtatt ttgtcgtgtc ataaacacca
    90601 atcatatttt tcatgattag atccagataa gaagtcgctt ctgttttcaa cgtagtgatc
    90661 tgactcagtg cctcgccatt tgaccgaaga tccagcactg ctggcaatac aatgatcatt
    90721 gaagcgccgc ctgccagtaa agaagtgata ccataaggaa caatcgtttt tttatattct
    90781 gaccagtttg tcaatagacg ggcgataaaa tataagaaag aaaatacgcc aatcataaaa
    90841 cccatataaa aactggataa aaacaagagt aaataactga taaataaaag tttcggccgt
    90901 ttaagatcca taacacgatg aatccccaaa atcactaatg gaagataaac aaatgcatcc
    90961 agccacatga tgatctccga atgtgcagtg ataaatgaga tcaatgcgta actgacgcta
    91021 agtgcaacat gcccccagcg aggaatcttg aacgtacgtg caagaaacca aaaagccaat
    91081 ccggcacagc cgaccttaag caaagtcaga acatacagtg catctggcat catctggttt
    91141 ggaaaaaaga acaccagtgg cgtgaagatc ccgcctagat agtaagaaat taaagataaa
    91201 taattcaatc ctagagaagc attccatgta taaaaaatac tttgctttcc aagaagaaca
    91261 tttcggaagc tggcatgaaa attagaaaac tgtgaaaagg catcacttgc caaaatactt
    91321 ctgctgcttc caggatagat tccgatactt agataaacaa gtgctaaaat caaaaacgga
    91381 atcaggaaac tagctgctgc gtagcgtccg ttttctctaa agaatgactt taaatttttt
    91441 ttcatattta ttttccacca aatttctatg aagttgtatt cagtttatca tatccttgtt
    91501 tttctctgct taaaaagagt ctagttttca caaaaaaata aaatttagaa taaataactt
    91561 cataatttgt tcgtataaca aaaataaacg caaaaaaagg gtaggaatca aaagtcccac
    91621 ccttaaaaat ttttattaaa taaaaaaccg ttcactatct gaacggtcca agtatcattc
    91681 aattaaacgc gttcaacttt tcctgatttc aaagcacgag ttgacaccca aactttttta
    91741 ggttttccgt cgaccataac gcgaactttt tgtaagttag gtttaacagt acgttttgtt
    91801 gagttcatag cgtgtgaacg gttgtttcca ctttttgtct tgcgacctgt aaagtaacaa
    91861 acttttgcca tggtaatttc ctcctttgcc ttgatttgga gcaatagaat aattcagctc
    91921 ataccagact aacatatcat atagaatggg aatttgcaag tacattttca tagatacaat
    91981 tgacaattga gaagaataat tgtaaattaa acaaggttat acctgaaatt ttgcaaggtt
    92041 tttgagtact ttgggtaact gccttttatt tcaagttgcg ctatgataaa atatgataga
    92101 agaaaaatgg gagtttttta cccgttaagg aggctcattc atggctgtaa aaattcaaac
    92161 gtcagctgga accattgaaa ttaccaatga tgtaattgca acagttgttg gtggcgccgc
    92221 gacagatgtg ttcggtgttg taggaatggc cagcaaaaat caaattaaag ataatattac
    92281 tgagattttg cgtaaagaaa attactcaag aggagtagtt gtccgccaag aagataatgg
    92341 tattgctgta gatgtttata cgattatcag ctatggtacg aaaatctctg aagtttcccg
    92401 caacgtccaa gaaaaagtga aatacaatct agaggcatta ttaggcgtaa ctgccaattc
    92461 agttaatgtc tttgtacaag gtgttcgtgt actgccagac taggcaggag actggctggt
    92521 aactcagcag tcgatctgaa ggaggattat ctaggtgagt gtaacagaaa taagtgcaag
    92581 ccagttccag gaaatggtcc aggcaggtgc gaatcgtctg caagtaaatg cagaatacgt
    92641 caattcatta aatgtattcc ctgtgccaga tggcgatacg ggaacaaata tgaatctatc
    92701 tatgactagt ggagctaagg cagtagtaga ttcaacctca gaaaaagtag gagaattagc
    92761 agcaatgctt tcaaaaggat tgctgatggg tgcgcgcgga aattccggcg ttattttgtc
    92821 tcaattgttt cgtggatttt ctaagcaaat tccagatgtt gtctcattaa atgcttctga
    92881 tcttgctgca gccttcactc atggagttga aactgcgtat aaagcagtaa tgaaaccagt
    92941 agaaggaacg attttgacag tagctagaga agcagcgaaa gctggagaaa agaaagcaaa
    93001 aagtactgat gatgtcgttg aagtaatgac agctgttgta aaaggagcaa agcgtgcttt
    93061 agctaaaact ccagacttgc ttccagtcct aaaagaagtc ggtgtcgtag acagtggagg
    93121 gcaaggactg ctgtttgttt atgagggctt tttaagtgca ttgaatggag aattccaagc
    93181 ggatgaaaca tatgaacctt ctccagcaga aatggatgat atggtcaatg cagaacatca
    93241 tcgcagtgtc caaggtcaaa tggcgacaga agatatccat tttggttact gtacagaaat
    93301 catggtaaaa atcggagaag gacctacagt cgatagtaca ttcgattacg aagaattccg
    93361 taactattta gatggtatag gagattcttt acttgtggtc aatgatgacg agatcatcaa
    93421 agtccacgtg catacagaaa acccaggaga agtcttgaat tatggacaaa aattcggttc
    93481 attagtcaaa atcaaagtcg acaacatgcg cttgcagcat gagacgattt tggaacacga
    93541 tgaagaagtg aacgagtttg cgaaaaaaga aataccacgt atcccgtatg gtatcgtagc
    93601 gatcgctgct ggtaaaggcg tccaagagct gtttgaaagt ttaggcgcta attatgttat
    93661 cagtggtgga caaacaatga atccaagtac ggaagacatt gttaaagcga ttcaagaagt
    93721 aaacgcagat aaagtgattg tcttgccaaa caataagaac atcttcatgg cagctgatca
    93781 agcagcagaa gtagcagata tcccagtagc agttgttcct tcaagaacga tttcccaagg
    93841 attgacagct atgctttcat tcaatgatca agcttcttta gaagaaaaca aagaaacgat
    93901 gacagaaatg ttgtctagcg ttgtgagcgg tcaagtcact cacgcgatca gagatacctc
    93961 aattgacggt gtagagatca aagaaggaga ctttttgggc atgatcgatg gaaaaatcct
    94021 gatctctaac ccagatatca cagcaacagc gttaagtaca ctagaacaaa tgatcaatga
    94081 ggacacagag atcgtaacga tcttggcagg tgatgaagga acagttgaac aagcaaatga
    94141 atttgctgag aaactaacag aaaaacatcc tgatttggaa atcgagatcc accaaggaga
    94201 tcagcctgtc tatccttatc tattttctgc tgaataattt ctgtgtcaga atatctttct
    94261 aacacagtat tcattcataa aaggccttcg gttagtgatc aggtatgatc gctgaccaag
    94321 tccttttttt gttaaaggag ggaggaaaaa tttatgcgtt ctttagatga tccaatcact
    94381 atgctggcag gagtcggaga aaaaagagca gctagtcttg ccagcttggg catccaaacg
    94441 attgaagact tactgactta ttatcctttt cgctacgaag atattcagga aagaaatcta
    94501 aacgagatcc aggatcaaga aaaggttact ttgaaaggaa tcgtagtctc gcctcctgtg
    94561 atgaatcgat ttggttataa aaaaagccga ttgcaatttc gtatgatgca agaacatgat
    94621 gtgttcaacg tttctttttt taatcaacct tatctaaaag aaaaagtcat tttatcggag
    94681 gaaatcgccg tatacggtaa atgggatgca aagcgtaaag ccttgaacgg gatgaagatt
    94741 ttaggttctc aaacaatgga tgacttttcg ccgatatatc acgtcaacaa atcaattcgt
    94801 caaacgacat tagttgatct aatcaaaaaa gggtttcaag aatacggcac attgattgaa
    94861 gaaaatctgc caaacaacct tgtggagaaa tatcgactgc ttgaccgagc ttctgctgta
    94921 agaagtatgc attttccaaa agaccacgaa gaaaaccatc aagccaaacg acgtgtcgtt
    94981 tttgaagagt tctttttatt tcaaatgcgt cttcaaggat tgaaaaaagc agaaaaagca
    95041 gaaacgaatg gtttggagat cctttatgat gtccaaaaat tgaaacaatt tactcaaaag
    95101 ctaccttttg aactgacaaa tgcacaaaaa cgtgtaacga atgaaatctg tcgggatctt
    95161 cgcagtccgc agcatatgca gcgacttttg cagggagatg taggtagcgg aaaaacagtg
    95221 gttgccgcga ttgcgttata cgctaccgtt acagcaggtt tccaaggtgc gttgatggtg
    95281 cctacagaaa tcttggcaca acaacatatg gaaagcttgc aacagctgtt tgatcccaat
    95341 gaagtaacca tcgcattgat tacggggtca acgaaagcaa aagaacgacg tgagctcctt
    95401 gaaaaactag agcaagggga aattaacgtc gtgatcggca cacatgcatt gatccaagat
    95461 ggagtcgaat ttcagaattt aggtctagtt attacggatg agcagcaccg ttttggcgtg
    95521 aaccagcgga aagtacttcg tgaaaaaggc tggcgaccag atgtcttatt tatgacagcg
    95581 actccgattc ctagaacatt agctattaca gcatatggtg agatggatgt atctatcatt
    95641 gatgaacttc cagctggacg tatcccgatc gaaacacgct gggtaagaac acctcaattg
    95701 gacagtgtac tggattggac gaaaaaagaa ctggcaagag gacatcaaat gtatgtcatc
    95761 tgtccgctga ttgaagaatc agaagcatta gatgtaaaaa atgcagtgga aatctatgaa
    95821 aaacttcgtg aactatttgc accaaaatat gaagttggct tgttacatgg taaaatgaag
    95881 aatcaggaaa aagaagtaat catggaagcc ttcaaagaca accagatgca gatattagtt
    95941 tcgactactg taattgaagt aggggtaaac gtgccgaacg cgaccgtcat gctgatcatg
    96001 gatgcggatc gatttggatt ggcacagctg caccaacttc gtggacgtgt tggacgcgga
    96061 agtgatgctt cctactgtat cttagttgct aatcctaaaa atgaactagg tgtggaacgg
    96121 atgaaaatca tgacagagac caccaatggt tttgtactaa gcgaaaaaga tctggaatta
    96181 cgtggtcctg gtgaagtatt tggcttccgt caatctggtc tgcctcaatt tgcgattgct
    96241 gacttggtga cggatggaaa tgttttggag gtagccagag aagaggctgc agccctttgg
    96301 caaataaagg attggcagat gcttcctgag tatcagcctt tagcgcaaag cctccaaata
    96361 gaaaatcagg ataatcgtta tttcgattag cagactgtgc tatactttat actgatgacg
    96421 gaaaaaggag tggaaacaat gaaaattgcc gtagatgcaa tgggcggaga tcacgcacct
    96481 caagcaattg tagaaggcgt ggctttagcg cagcaagatt ttccagaagt agaattctta
    96541 ctttacggaa aagaagcaga aatcaagaaa tacttaacaa atgaaaaaaa catcacgatt
    96601 atccatacag acgaaaaaat caatagtgat gatgagccag taaaagcaat tcgacgaaaa
    96661 aagactgcat caatggtcct tgctgcacaa gcagtgaaaa acggtgaagc agatgctgta
    96721 ttttcagcag ggaatacagg cgcgctacta gcagcagggt tgttcatcgt aggacgtatc
    96781 aaaaatatcg aacgccctgg cttgatgtct accttgccag tagtagggaa agaaggtgcc
    96841 ggtttcgata tgctggatct tggcgctaac gcagaaaaca aaccagaaca tttgttgcaa
    96901 tacggtattt taggttcttt ttatgcacgt aaagtccgag gtatcggacg tcctcgtgtc
    96961 gcactcttaa acaacggaac agaagcaaca aaaggtagtg aagtgacgaa aaaagcctat
    97021 gaactccttc agaatgaaac aagcttgaat tttattggaa acgtagaagc tcgtgagcta
    97081 ctcaatggtg tggctgatgt agtggtcaca gatggattta caggcaacgc tgttttgaaa
    97141 tctattgaag gaacagcaat gaatatgatg aatctattaa aatctgctat tctaaatgaa
    97201 gggatcaaag gaaaaatggg cgctatgctt ttaaaagacg gcttacgttc tttgaaagca
    97261 gaaatggatt attccaaaca tggcggtgcc gttttgtttg gcttgaaagc accagtcatt
    97321 aaaactcatg gagcaacagg ccccgatgct gttcgctata cgatccgcca aatccacaca
    97381 atgcttgaga cagatgtagt tggacaatta gtcgaacaat ttgaaaaaag cgaagaatag
    97441 tatttggata tctgaagcga tccgttccat tgaaaaaaag gtggacattc ctgaaaaatg
    97501 ccagtaaaat tagccatggt gtaggtaatt gacaagtgta tgattcttgg aggtgaaaaa
    97561 gttgactcgc gaagaagtat ttaacaaagt agcgaaaatt atttcaaatc attttgagat
    97621 agataccgat aaagtgacgg atgaattgaa catcaaagat gatttaaaag ctgattcaat
    97681 tagtattatg gaattcgttt tagagcttga agatgaattc ggtacggaaa tttcagatga
    97741 agacgctgaa caaattgaaa cagtcggtgg cgcagtagat tatatcagca gccatcttaa
    97801 ataatttcaa ataaaagcaa agaaggataa aaagctgcat gcagcttttt atccttcttt
    97861 ttttaatctt tttgacacgt aaaagtcatt tttctgataa ttctggcgat aaacagaaat
    97921 tatgttgcaa agtaaagcgg ttttctatat aattattaat aattcattac acaaagataa
    97981 gaataacctt tgttataaaa cgatttattc tgtgtaatgt ccttttttat taagaaaaac
    98041 ttccatttag gaagcagaga ggggtattcg attgtccgat aaccaattat tagaagttca
    98101 gaacctacat acaggattcc gactcaaaga tgactattac gatgcagtag atgacgtttc
    98161 atttacttta gacaaaaacg agattttagc aatcgttggg gaatctgggt gcgggaaaag
    98221 taccttggct actacgatta tgggattact tgatcctaat aacacaaaaa ttacaggtga
    98281 gattttatat aacgatctga atttaatcga cctgaacgaa acgctctata ataaaatccg
    98341 cggaaatgat atcggaatga ttttccaaga tccgttgtct gcattaaatc ctctcatgag
    98401 aatcgaagac cagatcaaag aaggactttc ctatcacaca aagatgaatg cagaacagcg
    98461 tcaagctcgt gcactagaat tgctagaaca agtagggatt cctaatcctg cgagagttgg
    98521 acgccaatat ccccatgaac tatcaggcgg tatgagacaa cgtgtcatca tcgcaatcgc
    98581 aatcgcctgc aaacctccaa tcgtcattgc agatgaaccg acgacagccc tagatgtaac
    98641 catccaagca cagattcttg atttactgaa agaccttcag gaagaaacaa aaacagggat
    98701 catcttgatc actcatgact taggagtcgt agcagaaatg gctgatcgag tggcagtgat
    98761 gtatggcgga cagttcgttg aagtagcagg tgtaaaagaa ctgtttgatc atcctaagca
    98821 tccttataca cgctctttac tgaactctat accacaagaa ggaaatcatg atgcagaact
    98881 ccatgtgatc gaaggtgtcg ttccttctct gaaaaacatg cctcgtaaag gttgtcggtt
    98941 tgcaccacgt attccatgga taccagcaag cgatcatgaa gaagagccta tccttcatga
    99001 agtcgcaccg aaccacttgg tacgttgctc ctgctataag catttccact ttagagacga
    99061 aaaaggagag gtgtagatga cagaattaat cacaatcaaa gacctgaaag ttcattaccc
    99121 tattcgcagt ggattcttca atcgagtaac ggatcatgta tatgctgtag atggtgtgga
    99181 ttttattatc gaaaaaggaa agacatatgg tttagtggga gagtctggct ctggaaaatc
    99241 tactacggga aaagccgttg tgggattaga aaaggtaaca gccggacaaa tcatgtatga
    99301 aggaaaagat gtaacgaagc gaagcaaccg caaaaaaatg ggttataaca aggatgtgca
    99361 gatgatcttc caagattcaa tgtccagttt gaatcctaaa aagcgagtgt tggatatcat
    99421 tgctgaaccc atccgaaatt ttgaacggtt aagcgatcaa gaagaaaaga aaaaggtaaa
    99481 aggactgcta gatatcgttg ggatgccgga agatgcgcta tataaatatc ctcatgaatt
    99541 ttcaggcgga caacgtcaac gtctaggagt agcccgtgct gttgctacca atccaaaact
    99601 gatcgtagcc gatgaacctg tatctgctct ggatctatct gttcaagcgc aagtattgaa
    99661 tttcatgaaa cgaatccagc aagaatacgg cctcagctat ttattcattt cacatgattt
    99721 aggtgtagta aaacacatgt gcgacaatat cgcaattatg tacaaaggtc gatttgtaga
    99781 aatcggtaca agagaagaca tttataatga cccgcgacat atctatacga aacgtctgct
    99841 ttcagctatt ccgcaaatcg atgtagaaaa tagggaaagc cacaaagaaa atcgacgaag
    99901 agtagaacaa gagtatatcc aaaaccaaaa agaatactat gatgcgactg gtcgagtcta
    99961 cgatttgcgt acgatcacaa ctacacacaa agtggcgttg aaagatggag gtgcaagcta
   100021 atgtggaaaa cgattctgcg acgtgtttta ttgatgatcc cgcaagttat tattttaagt
   100081 gttctgatct tcttattagc ccaagcgatg ccgggggatc catttaccgg tttgatcaat
   100141 ccaaatcagg atccggcagt gatcgaacag atgcgacaag cagctggctt gaatgaccca
   100201 tggtatgtcc agtacttccg ttggatcgga aatgctttgc aaggcgattt tggtcaaagt
   100261 ttcttataca aacgctctgt tgctgacttg atcggcgaac ggatcatcaa cactttatat
   100321 ctatcgatct tgacagttgt ccttacttat ttgattgctg tgcctctggg gatgcttgct
   100381 ggccggtatc aaaattcaat cttggataag attgtcgtaa tctacaactt ctttagtttt
   100441 gctgttcctt tatttatctt cggcttgatc atgctatttg tttttggtta tcgtttaggc
   100501 tggttcccaa caagtggatc acaaacacta ggtttgcaag gtggatttat cactcaatgg
   100561 atagaccgtt tgaaatatat tctgttacca tcaattaccc aagcattttt ggcgactgcc
   100621 gtcacaatcc aatatctgcg aagtgaagta atcgattcga aatcgctcga ttttgtcaga
   100681 acagcccgtt ccaaaggggt accgacgaat aaagtattca gtcgacatat tttccgaaat
   100741 gcagcgttgc cgatggcttc tcaaatgggg tatgaaatca cttcgttgat tgctggttct
   100801 gtagttatcg aaaagatttt tggttatccg ggagtcggaa aactatttat tgattccatc
   100861 ggccaacggg actataccgt gatcacatcc ttagtattga ttttaggaat cgcgacgcta
   100921 gtggggacat tactttcaga tatcatcatg agtatcgttg acccgcgtat tcggattcaa
   100981 taaaaccaat cagaaaggag aatggatcga tgagtgaaaa aaacaataca gcagttcaag
   101041 aaagtattcc tcctatgggg atacgaatga ttgctcgaga atttaaaaaa gataaaattg
   101101 ctattttttc attaggtttg ctagtggttt tattattagt gatctttatc ggtgcgatgc
   101161 tgaccgatca agacaaagtg atgtatgtta gtatcttcga caaatacgct gcaccaggaa
   101221 cagtttcgac acaaggacaa aagttcattc tgggagcaga tgaaggcgga cgtgatgtat
   101281 taggacaatt gatcataggt gctagaaact ctgttacgat cggatttgcg atcacgatcc
   101341 ttacttcgat catcggggtt ggattaggga tcatctctgg ctactacgga gggatcattg
   101401 acaacatctt gatgcggatc gttgatttta tcatgattct accgatcatg ctgatcatta
   101461 tcgtcttcgt atcgattatt tccagataca atgtctggtc ctttatattc atcatgagtg
   101521 cattttattg ggtagctaaa gcccgattat tccgaagcaa gacattatct gaagcaagaa
   101581 gagattatgt cagtgcctca aaaacaatgg gaaccaatga ttttaaaatc atgttccgcg
   101641 aaatcatgcc gaatctaagt tcattaatca ttactaattt gacgatgaac tttgcggcaa
   101701 acatcggtat cgagacaact ttgactttct taggtttcgg cttgccggca aatgtaccta
   101761 gtttaggtac attgatcggt tatgcaagta acggagaagt cttagtgaat cggcaatgga
   101821 tctggttacc cgcatcaatc cttattttag ttttgatgtt gagtatcaat tatgttggac
   101881 aagcattcaa gcgttctgca gatgcgcgcc aacggttagg ctagtataga agcgaagggg
   101941 gaaataggaa tgaagaaaac gatttttgga tttgcagcgc tgatgtctgc tgtcgttctt
   102001 gcagcatgcg ggggcggagg tacagatacc tctggaaaca actctggagg caacggcaat
   102061 aacaaagagg aattaacttt tccaattgca acaaaaaata atgatgatgc aatcgaagac
   102121 ggcgaattag aagctgcggt cgcaacggac agtcagttta aaggattgtt ccagtgggag
   102181 ttttaccaag attcatatga tgcagctttt atggctcctt ctcatgaacc gctatttgca
   102241 aacgatgacg atttcagaat cacagacgac ggagctgcaa cgcttgatct agatgaagat
   102301 acgaaaaaag cgacaatcaa agtaaaagac aacgtcaaat ggtcagatgg tgaagatgta
   102361 acggcggacg atgtgatttt cccttacgaa atcattggga ataaagatta cactggtatc
   102421 cgttatgacg acactttccg taacatcgta ggtatggaag aatatcatga tggaagtgcc
   102481 gacacaatct ccggaatcaa aaaaatagac gacaaaacag ttgaaatcga atataaagaa
   102541 gtaaacccaa gcatgcttca atcgggtggt ggtatctggt catatgcagc accaaaacat
   102601 acgttagaag gtgtagcaat caaagatatg gaatcaagcg atcaagtacg taaaaatcca
   102661 gtgacttttg gcccttatta catgagtaat atcgttgcag gagaatcagt agaatacttg
   102721 ccaaacgagc actactggaa tggtacgcct aaattgaaaa agatcacgat gaaatctgta
   102781 ccgatggcaa gtgcaactga agcattgaac tctaaattat atgatatgat tttccaaatg
   102841 ccaacagata cttacgatac ctataaagaa attgctggct atacaaactt aggccgtgaa
   102901 caaacttctt atacttatct aggattcaag ttaggtaaat ggaatgcaga tacaaagagt
   102961 gtggaataca atccagattc aaaaatggct gataaatcat tacgtcaagc aatgggctat
   103021 gcattagata ataatgcagt aggtgaacgt ttctatgcag gtttgagaag caatgcgact
   103081 tcattgattc ctccagtatt ccagtcatac catgatgatg agatgaaagg attcacacaa
   103141 gatctagaca aagcgaaaaa actattagat gatgctggct acaaagatgt ggatgacgat
   103201 ggtttaagag aagacaaaga tggaaataaa ctaacaatca actttgcttc gatgtccggt
   103261 ggggaaacag cgcaaccatt ggcagattac tatatccaac aatggaaaga aattggtttg
   103321 gatgtccaat acacaacagg tcgtctgatc gaattcaatt ctttctatga taaattagaa
   103381 aacgatgatc ctgaaattga tgtttaccaa gctgcttgga atacaggaac tgatccaaat
   103441 ccaagtggac tatggggacc aaatgctgcg ttcaactaca ctcgttatga atcagaagaa
   103501 aatacaaaat tgatcaacga tatcagttca agcaaagcat ttgatgaaga gtaccaaaaa
   103561 gaagcatatc aaaaatggca acaatatgca tttgaagaag catttgcgat tccaacgttg
   103621 ttccgtaatg aagtattgcc agtcaacgac cgtgtcaaag actgggattg gtcttatgat
   103681 gtaccaaacc catgggcaaa tgtttctgtt acagcagatt cacgttcata atcactaaaa
   103741 atgaccgaaa aagggcgatg tcctttttcg gttttttgat atttttctgt ttatttctct
   103801 aatattcagg tcaaggcgct gatttcatga cttctccaat aaacggtgtt caaagtccag
   103861 tttctcggta ttaagtcaaa tttatgcaaa aatatggaaa gccattttca caaaattttt
   103921 tcttcatact cgaaactaaa cgaatttttc acaacttctc gtcaatcact aggattatta
   103981 aagctttact taccttttga ccgaaccatt tcaaatttga caaaaaacca gtataataag
   104041 gaagtatcga aaaaatatcc ataaaaggaa tgtggaaaat ggacaaccag ctgacaaaag
   104101 aactaaaaga aaactataac atcgtttttc acgatctaaa tttgcttgaa caagctttta
   104161 cccattcatc ctatgtgaat gagcatcgca atctgcaatt atcggataat gagcgacttg
   104221 aatttttagg agatgccgtt ttagaactga tggtttctca gtatttattc cgtttatatc
   104281 ctcatttgcc agaaggaaaa ttgacaaaaa cacgagctgc gatcgttcgc gaagacagct
   104341 tgtcgaaatt tgccaaagaa tgtcactttg atcaatatgt tttgttgggc aagggagaag
   104401 agaattcagg aggacgtacg cgaccagcat tgctttgcga cctattcgaa gcttttttag
   104461 gcgcgttata tcttgaccag ggattcgaca cgacccatgc attcatcgaa aaagtgattt
   104521 ttcctaaagt caaagcaggt gctttttcac atgagatgga tcataaaaca aaactacaag
   104581 aagtcttgca aaaatcaggt gatgtatcaa tcgaataccg attgatcaat gaagaaggtc
   104641 cagctcatga acgagtattt tggatcgaag tttatgtaga tgatcaattg attggcactg
   104701 gacaagggaa atcgaaaaaa ttagcagaac aagctgcggc ggaaaatgca ttggcagcac
   104761 tgtaaaagta agtgagggaa agctttgtat ttgaaacgaa ttgaaatagc cggttttaaa
   104821 tcatttgcag acaagacagt cattgatttt gaaaatagcg tcacagcagt ggttggacca
   104881 aatggcagcg gaaaaagcaa tattacagag gctatccgct gggtattagg agaacaatct
   104941 gctaaaagtc tgcgaggcgg aaaaatgccg gatatcatct ttgccggttc cgatacccgt
   105001 aagcagctga atattgcaga agtcacagtg attttagaca atagtgatca ttatctgcca
   105061 ttggagtaca atgagatcag tgtaacccgc cgttatcgac ggactgggga aagcgagttt
   105121 ttcatcaata aacaaagctg cagattaaaa gatatccaag aattgttctt agattctgga
   105181 ttaggaaaag aatcgttctc aatcatttct caaggaaaag tagaagcgat tttcagtagt
   105241 aaaccggaag accgtcgtgg gatctttgaa gaagcagctg gtgtcttgaa atacaagcag
   105301 cggaaaaaga aagcagaaca gaagcttttt gaaacagaag acaacctcag ccgcgtccaa
   105361 gacatcatcc acgaattgga agaacagtta actcctttgg ccgcccagag tgaggcagca
   105421 aaggagtttt tacggctaaa agaaacactg actcaaaccg atgtctcttt gatggttgct
   105481 gaaatcaaga cagcaaaaaa agattgggac aacaaacaag cacagcttgc gaaattcaat
   105541 ctagaattag gcaaactatc tgagtcgatc caagaacaag aatccatttt ggcgaagcag
   105601 cgtaaagaaa atgcgcaagc cgatcgtctg atcgaaaaaa atcagcaagt attattagat
   105661 ctttcggaaa aactgaagca gacagaagga caaaaagatg ttttgcagga gcggacaaag
   105721 catacacaaa aaagctcgca agaatatcaa acttcattag cagaagcaca aaaaaaggtt
   105781 aaacattttg aaaagcttca agaaagcttg atgaaagcag cagcagaaaa agaaacagag
   105841 atccaaaaag ctgaagcaaa tctcataaaa acacagcaag aattagaaaa ataccaaaaa
   105901 tcaacgaaag aattattggc agaattaaga gatcaatatg ttgatttgat gcaagaacaa
   105961 gcagctgtag gaaacgaact gaagtatcta gaacgtcaat atatacaaga aacagcaaaa
   106021 agcaagcaga cgttagccaa gcaatcggaa gtagaagcat cagtagaccg attgatctta
   106081 caaaaagaag aattgacaca aaagcaggcg cagctaaaat catctttaac tgaaacaaaa
   106141 gagaagttag aaatgatcca acaaaacggg aaaaagttcc aagaagcatt agcaaaagaa
   106201 cagcctaaaa tgtatcaatt aatgaatcaa gtccagcagc tacgtgctcg taagaaaagc
   106261 cttcaagaaa tccaagaaaa ctattttggt ttttaccaag gggttcgatt ggtcttgcag
   106321 cataaacagc agctttcggg tattgtcgga gcagtggctg aactgatcga tgttcctgca
   106381 gatttcacgt tagctatcga aacagcttta ggtggggcag cccagcatgt catcgttgaa
   106441 aatgaaaaag atgctcggca agccatcacg tatttgaaac agcaaagagg aggaagagca
   106501 acattccttc cactgacgac aatcaaacca agacaattac cggctcatat attgacacaa
   106561 gcagcagctg tagaagggtt tatagggatt gccagtgaac aagtcagtta tcccgatcaa
   106621 atccaaactg tggttcaaaa cctgctagga acgatccttt tagccaaaga cttaactagt
   106681 gccaatgcaa tcgcgcaaac gatccgctat caatatcgag tggtttcctt agaaggtgat
   106741 gtgatgaatg ccggaggatc catgacaggt ggagcgaata aacgaggaaa ccaaggcagt
   106801 ttgtttgtac aaaatcaaga attgaaacag ttgactagtg aatttgaaga agcagataaa
   106861 caactccaag cacaagaaaa aaaagttcag gagctgcaac aagaaacagc tcgtttagcc
   106921 gaagaacaag aagttttgcg tacacgaggc gaacaattac gttttgaaga acaagaagcg
   106981 acaaatcagc tacaaaacat cataaatgaa cttgaacgtt ttgaaaaaga aaagcaaatc
   107041 tcaacttttg agacacgtga actgcagcag tttatcgaag attacgaaaa gcaaacgaac
   107101 gaattgaaag acaaacaaac agatcttgaa tcgcaacgac aaaaaatcga cgaagaaatc
   107161 aaatcgttaa gtcaagaaag cgaccagatg gaagccagaa gagcacaagt acaaagtcaa
   107221 aaagcacaag aacaagcaga tcttgctgtc ttgaaagagc agtttaatca tctgcagatc
   107281 cagctccgcg gtgcccgagt ccaaaaagca gaggcaaccg aacgtcaaga agcgatagaa
   107341 aagcagttgg cgacattgac agcagacttt tctgatcatg aagtcacaga agaaagtttg
   107401 gaaaaacaaa ttaacgaatt atctgctcag cgagaaacat taaaagccga gttggcaaaa
   107461 gccaaagagc agcgagatag aaggcaaaag gagatcgata agcttgaagc agtcttggca
   107521 gagcgtaatc gtgagcaaaa agcacgactg tcggaacaat ccaaattaga agtccaaaaa
   107581 gaccgagctg aaatgatttt agataatcat ttgacctatc tgcagtcaga atatcagctg
   107641 acatttgaga aagcttccca agactatcaa gaaacaaccg atatcgaaga cagtagaaca
   107701 aaggtttcat ccttaaaaga acagattgaa aaactgggac cagtaaactt aaattcaatc
   107761 gaacaatacg aacaagtcag tgaaagacat acattcttag caacacagcg agatgatctg
   107821 ttagcagcga aaaaccaatt gtttgaaacg atggatgaga tggatgatga agtgcggaca
   107881 agattcaaag aagtatttga agctatccgt caagaattca aaattgtctt tccaaatatg
   107941 tttggcggcg gtaaagctga attagtactg acggaaccaa ctgatttgct gaaaacaggt
   108001 attgagattg aagtacaacc tcctggcaaa aaactgcaaa gtctaagttt gctttctgga
   108061 ggagaacgag cacttacagc catcgcgttg ctcttttcca ttatccgtgt ctgtcctgtt
   108121 ccgttttgta tcttagatga ggtagaagca gcgttagatg aagccaacgt gaaacgtttt
   108181 ggtcgttact tgagcgattt ccaagatgac acacaattta tcgtagtcac acaccgcaaa
   108241 ggaacgatgg tcgcagcaga tgtactgtac ggagtgacga tgcaggaatc cggtgtatca
   108301 aaaatcgttt ctgtacggat ggaagatatc aatgaagagg cgaaaatcaa cgaaacgaaa
   108361 gtgtaggaac gaaaatgatc aaattagtag caatcgattt ggacggtaca ttattaaatg
   108421 aacaaaagct gatttcagat gagaataaac aagcattagc acaagcaaaa cagcaagggg
   108481 tcaagatcgt tctatgtaca ggacgcccct tagctgcgat ggcgcattat ctgcaagaat
   108541 taggactggt agatgaaggt gactacagca tcactttcaa cggcggtttg gtacaaaaaa
   108601 atgatactgg tgaaatcatg gaaaagaaag tgatggaagt atcagatatc caacgcttat
   108661 acaaactggc tcagcaattg gatctgccac tagatgtttt gtctgacaat gtggttttac
   108721 agctgcctag tgccccaagg aagcaatcct tgtacaatgt gttgaataag ctgctgcaat
   108781 tccaaccagc ggatataagc gatattacag atgaatttgt gcttaataag gcagtaatcg
   108841 cttatgacca agaagaatta gatcctaaaa tcaaagaaat accagcagaa ttccatgaaa
   108901 tgtatgagat catcaaaaca agaagtatgc ttttggaatt tatgccaaaa ggtgttacaa
   108961 aagcttatgg tatttcttta ttggcaaaag atcttggttt gaaacaagaa gaaatcatgg
   109021 cgatcggtga tgaggaaaat gatttaccga tgatccaata tgctggacta ggcgtagcga
   109081 tggagaatgc tgtgcctttc gtcaaagaag cagcagattt cgtgacagcc agcaatgaag
   109141 aaaatggcgt agccaaagtg atccaaaaat ttgtattaga gtagggggag tcaaatggga
   109201 ttttttgata aaatcaagcg tgcttttact ggcgaagaga aaacagaaga agttgaagta
   109261 caggagaagt acgacaaggg tttagaaaag acgcgtaaaa catttggtga acggatgaat
   109321 gagttgtttg ccaattttcg aacagtcgat gaagactttt ttgaagaatt agaagaaaca
   109381 cttatcggtg cagatgtagg ttttgaaaca gcgatacgaa ttaccgaagc attacgtcaa
   109441 gaagtgaaac tcagaaatgc gaaaaaatcg gcagaagtcc aaaatgcgat catcgagaaa
   109501 cttgtggatc tctatgaagc ggaaggaatc aatgaagtaa atgaactaaa tatccaagaa
   109561 gacggactaa cagttatttt gtttgtcggt gttaatggtg tagggaaaac aacaagtatt
   109621 ggtaaacttg cccatcagtt caaaaacgaa ggtaaaaaag tattgatggc agcagcagat
   109681 accttccgcg ctggagcaat cgaccagtta gttgtctggg gcgaacgcgc tggtgttgaa
   109741 gttgttcgtg gcaatgcagg aggcgatcca gcagctgtcg tattcgatgc tttggaaaga
   109801 gcaaagacag agcaggcaga tgttttacta gttgatactg caggccgact gcaaaataaa
   109861 gtgaacttga tgaacgaatt agaaaaaata aaacgagtaa tccagcggga attaccagaa
   109921 gcaccccaag aaacacttct tgtattagat gcaaccactg gtcaaaacgc gatggttcaa
   109981 gcaaaacaat tcaaagaaac aacagatgtg accggtcttg ttttgacaaa attagatggt
   110041 acagcaaagg gcggtatcgt acttgctatc cgtaatgaat tgcatttacc agtgaaattg
   110101 gtcggtcttg gtgaaggaat cgatgacttg gagccgtttg atccaaatga ttttgtcgtt
   110161 ggattgttca aaggattact aaaagaagaa taacccatgt ctaaaaagca ggagctgtga
   110221 caaaagttgc agctccttgt ttgaatgatt gtttttaaca tagctgtgtt tttgatgcct
   110281 tcatttttat acttatttgt aagcggttct caaacaattt cgttcttttt cttagacttt
   110341 ttgattataa ttagattcat atgaattgga ggtcacttaa tgatgaattt taagcaatta
   110401 ttattgcatg tcaatgcgcg cccttttatc gaccaagctc gatttggtat agaacgggaa
   110461 ggacagcggg ttgatcttgc aggaaatcta gcaaaaaccg atcatccagc aatctttggc
   110521 gatcgatcct atcaccccta tatccaaaca gattttagcg aaacacaaac agagatgatc
   110581 acccctgtta ccgattctat tcccgaatta tttcagtatc tcgctgctgt ttatgatgtg
   110641 actgctcgtt ctataccgaa agaagagatg atctggccat taagtatgcc acctgcctta
   110701 ccggaaaaag acgaagagat cattattgca aaattaaaaa atttcgaaga tgtcttgtat
   110761 cgacgttatt tagcaaaaga atacgggaag cgaaaacaga tggtaagcgg tattcatttc
   110821 aattttgaat ttggcgatga gttgctaaga acattgttca gccatcagga agaatttcaa
   110881 gatttttccg aattcaaaac agaactttat ttgaaaacag cgagaaactt tatgcgctat
   110941 cgctggatga tcacttattt attcggtgct tcaccaatga gtgagaagaa ctacttttta
   111001 gatgaatcac atccgcaaga acctgttcgc agtattcgca acagtgcgct gggctatacg
   111061 aatcatccaa atgtgaaagt ttcctatgct tctatgaaac agtatttagc agatatcgag
   111121 cgaatgatcg aagaagggaa actttcggag gagaaagaat tttatacacc gcttcgtttc
   111181 cgaggcggaa agaaagtcgc agatttagca acaacaggtg ttcgttatat tgaattgcgg
   111241 aatatcgatt tgaatcctta tgcaagattg ggtatcaatc cagagcaagt tcggttctta
   111301 caattattcc tgatgtacat gttatggaca gaagaaaaag aagactgtga ccaatgggta
   111361 gcagaaggta cgactcgaaa taacaaagta gcactagaac aaccatcaga tcaaacagaa
   111421 tttcatcaag aaggtagaga aattcttgaa ggaatgaagc aaatgctggt tgaattggat
   111481 tggttggatt ctctttattt agtagaggaa gcattgactc aaatggatca tcctgaacaa
   111541 acgttagcag cgaaactcta tcaagaagca cagctatcga gtcagcaaga agttgctgtg
   111601 gcattgggac atcaatatta taaagaaagc catgaacgtc cctatcagtt ggccggtttt
   111661 cgcgaaatgg aactttctac tcagatattt atgttcgatg ccatccaaaa aggtgtccaa
   111721 gtcaaagtat tagatgagtc ggatcaattt ttgcgtctgc aattccaaga ccatgtagaa
   111781 tatgtgaaaa atgcaaacat gacaagtaag gacagctata tcgtcccact tatcatggaa
   111841 aacaaaacag taacgaaaaa agtcttaaaa gaagctgggt tccgggtacc aggaggcgca
   111901 gaattttcat ccatggaaga agcggtaaaa gcttatccga gatttgccga gcaggcattt
   111961 gtgatcaaac ctaaatcaac caattacggg ttaggtatca cgattttcaa ggaaggagct
   112021 agtctggaag attatcaagc aggtttagcc attgcttttc gtgaagacag ttcggtttta
   112081 gtagaagaat ttatgccggg aacggaatat cgtttctttg tgatcgacgg agaagtccaa
   112141 gccatcatgt tgcgagtccc tgctaatgtt attggtgaca gtatccgaac agtgaaagaa
   112201 cttgttgaag aaaaaaatag tgaccctttg cgtggaacga atcatcgtgc acctttagaa
   112261 ttgatccaat taggtgaatt agaacaattg atgttgaaag aacaagggtt gacgatcgaa
   112321 tcagttcccc aagccaatca aattgtttat ctaagggaga actcaaatat cagtacaggt
   112381 ggtgattcga tcgatatgac tgatgaattt tctgaagctt acaaaaaaat cgccgtttct
   112441 gcggtagaag cactaggagc taagattagt ggtatcgatt tgattatacc agataaagaa
   112501 atcgatccta caactgataa aaaagcatat gggatcatcg aagcaaattt caatccagcc
   112561 atgcatatgc atgtttatcc ttttgcagga aaaggcagaa gattgacgat gaatgtattg
   112621 aaattgttat atcctgaagt attttaaaag aaaaagcttt tgacagattg tcctatttga
   112681 tgtcaatctg atcaaaagct ttttttgcat gtaaaaattt atgtgttttt tcgttttaaa
   112741 ataaacgatc ccagaagctt tttttctttt ttggtttttc tttttcagct ggcgaagagt
   112801 tttcttctgg gtattttttt tcgatatcaa tcacaggttc atttactgct tcttttgctg
   112861 ttaagagcaa tccgaattcc tcaggatttg cagtgacgta atcgttgact acagtgaaac
   112921 ggctattgct tttcgttgct agctggatat attggttttg gacagaaagg ggtagagccc
   112981 cattcaagag tatggaagca tctggatgtt ttttgagttc ttttaaaaag ttttctttgt
   113041 tttttggttg gatcatttca gcaacagtca tactaagata gcagcgttcc ctgaatgtcc
   113101 ctaaatattt atgctgttct tcagggttca ctaaaggtgt accataaagt cccttatcca
   113161 aatggctttt tacatcatct tgtgccataa aaaataccct ccttcttctc tttgtctttc
   113221 ttacgattat agcatattcc caataatacc taaaacatat gaaaaagcgg ttgcttttgt
   113281 tcaacgattc acttaaaata agaatgaaaa tcattctcaa ttagaaaggt ggattggatg
   113341 cgctacggac gactagtagc attattagtt attttaagta gtatttcatt gttcatcgga
   113401 gtatcgaatg tacaattgtc agaactgctc cagttagatg ggcaaagctt acaaatcttg
   113461 ctagtgactc gtttgccacg aacgatttgt ttgatccttg tgggagcgac cagtagtatt
   113521 tgtgggttga tcatgcaaca tttgacccaa aataaatttg tttcaccaac gactgcgggc
   113581 acgatggata gtgcgcgttt aggtatttta gtggctatga ttttcctacc tggtgcatcc
   113641 ttgattgtcc gatccttgac agcattttgc tttgcttttg caggaacatt gcttttttta
   113701 tcccttacgc gattgttcct ccagaaaaat caattgatgc ttccgttgat tggagtcatg
   113761 ttagggaata tcattggttc agttgctact ttttttgctt atcaattcca gttggtacaa
   113821 aatatgactt catggcttca agggaatttt gcgactgtga tacgaggaaa ttatgagtta
   113881 ttgtatgctg ttgttccatt gttgctcttg gtttggctat ttgcttaccg atttacgatc
   113941 attggtctgg gcgaatcgtt tgcagtaaat ctgggaatag attaccagaa gatgcagttt
   114001 ttaggcattg gcttagtatc attggctagt gcagtcatgt tgatcatggt aggaagcatt
   114061 ccttttatcg gagtgatcat tccgaatctt gtctctagaa tatatggaga tcaagtgcac
   114121 aaaacaattg gcgtaactgc tttagcaggt agtttgttct tagtattttg cgatcttgtc
   114181 gctcgcgtgt tgatttttcc ttatgaaata ccagtcagtg tgatcgttgg aatcatcggt
   114241 ggggctatct tcctttatct tctgataagg ggacgacgat atgcttaaaa aaaagccatc
   114301 tatttttatt ggtatgcttg ttcttgtttt atttgttaca ggaatgtact tgacgatcca
   114361 tacatatgga aactggcatt ttgcatgtgc attgaggagt aagaaaattt ttgcatttat
   114421 ccttgtctcg ctagctgtca gcagtgccac aatcagcttt cagacaatta cgcataacca
   114481 gtttttgact ccttcagtat tgggacttga gtcgttatat gtccttgtcc aaacggtcct
   114541 tttcttcttt atcggaggag tgacgatgct tcagcagaca ggtacagttt ttttcttatt
   114601 gaacgttggg ctgatggtcg ggctgagtct attgttattt ttctttcttt tgaaaaaaat
   114661 gagagcgaat ctttttttat tactgatgtc agggatgatt ttaggtacgc tttttggtag
   114721 tgtcagtacc tttttacaag tcatcatgga tccgaatgaa tatgatttgc ttcaaggcag
   114781 attatttgca agctttggca atatccagag tcagtatctt ttgcctgctt ctttgatcat
   114841 tatcggctgc tggtacctgt tatttcgata tcgacatgtg ctagacgttt tccatctcgg
   114901 aaatgaacaa gcagtaaacc tcgggataga cacagatcgt tttgaatttt tgattttatg
   114961 ttgtgtcagt cttttgacag ggacatcaac ggctcttgtg ggtccagtta cttttttagg
   115021 gtttattgtc gcaaatatca gttatcgtgt cttttctact tatcgtcatg gtcagctatt
   115081 tatcggaagc tttctggtag ctatgctgtt tctgacagga ggacagctcg cagtagagca
   115141 gattttcggc tggaatacaa cagtgagtgt cgtcgttgaa tttgtcggag gaatttattt
   115201 tgtcacaaaa ttgattcgcg aaaggaagag tatcctatga ttgatttaca aaaggtcaat
   115261 aaactgtacc atggaaaatc agtggttaaa gatgtacagt taacgattcc tgaaaagaaa
   115321 ttgactgctt ttatcggtcc aaatggtgct ggaaagtcaa cggtgttgtc gatgatcagt
   115381 cgtttgatac caaaagatac aggtgaaatc tatttagacc ataacgaagt aaaggcttgg
   115441 aaatccaatg aattagccaa aaaattatcg atcctacgac aatcgaatga aataaatgtc
   115501 caaatcaccg tgaaagaatt agtagaattt ggacgatttc cttatacgaa aggaaaattg
   115561 acgacaaaag acgaggaaat cgttcaggaa tcactggaac accttgggtt agaagaaata
   115621 gcggatcaat cgattgacac tctttcaggc ggtcaactcc aacgtgcgta tattgcaatg
   115681 gtgctagcgc aagacacgga ttatatttta ctggatgaac ctttgaacaa tctagatatg
   115741 aattttgcgg ttcaaatcat gcagatttta aaaaatttag tacaagaaat cgggaaaaca
   115801 attgttattg ttcttcatga tatcaacttt gctgcaagtt atgcagacga aattgttgca
   115861 atgaaagatg gacagttatt tacgcaagga acgacccaag aaatgataaa aaaagatgta
   115921 ttggatgaat tatacgaaat ggacatacgg atttgtgaga ttgaaggccg cagattctgt
   115981 ctttatttct aaaactaaca ttaggagaga agagatgaaa aaattagtag taggtatctt
   116041 gattctagca tcatttggtt tagcagcatg tggaaatagc aacaacacca gtcaggcaga
   116101 cacaaaaaaa agcagcacac aaactgaaac tacattgacg ataacagata gtaatggaga
   116161 ccaaatcgag gtgccaaata atccagaaaa agtcgtcgta ttcgacaatg gttctttaga
   116221 tacgatggat gctcttggtg ttggagataa ggtagttgga gcagctacaa gcagccttcc
   116281 tgagtatctt tcatcctata aaaaagtaga atcagcaggt ggaataaaag aaccagactt
   116341 agaaaaaatt aatcagcttc agccagatct aatcatcatt tctggccgac aaagagattt
   116401 tcaaaaagat ctaagtcaaa ttgctccgac cattttcctt tctttagatg cgaaaaatcc
   116461 atgggaatct ttccagcaaa atgtcactgc tttaggggag atctttggta agcaagaaga
   116521 agctaaaact caattagagg aattatctag tgcaatcgat cagacgaaaa agaaagcaga
   116581 agctactgac aaaaaagcac tagtcacact tgtgaatgaa gggcaattat cagcctacgg
   116641 atctggttct agattcggtt tcatccatga tttatttggc tttgaacaag cagatgatca
   116701 aatcgaagca tccactcacg gtcaaagtgt ttcttatgaa tatgtgctgg aaaaaaatcc
   116761 ggatatctta tttgtagtag acagaacaaa agctattggt ggagacgaca gcaaagatga
   116821 tatttctgcc aatgaactgg tagcacaaac gaatgctggt aaaaatcagc agatcatctc
   116881 ccttgaacca gatgtctggt atttaagcgg gggcggttta gaatcaatga aactgatgat
   116941 cgaagatgtg aatcaagcat ttaaatagca taaataacag aggattaaac tctcatacta
   117001 tgtaacaata atgtttctta cattcttaaa tagcaagagc ctatcctcaa agaagttatc
   117061 aaaaaccatc cgtaaaatcg tattgatgat tttacggatg gtttttattt atttgagaaa
   117121 tcttttttca acgtgaattc attatctaca tcatacgggt tgattctaga atggggagtg
   117181 gcaaaaaata gtgtgatcca ttttttcagc atcaagatcg cctcctttga tttgaatcaa
   117241 aggtacaaag cgaaacttag ataaaactta aatttagata tttttatttt gtaccgatct
   117301 cttctttaaa cgatgttcca tctgctgctt ctcggcaata agtccactag actagaaaat
   117361 atgagaagct attttctgtc cagcgttctt attactcaaa gcaaatcgca gttgtcacaa
   117421 tctcttctaa acaatgttca atcagctgac cttcggtatt agctcaaagc actgatttca
   117481 caacctctat ttaggcatgt gtctcagcaa gcggttgata gttgatgatc tgcatttttc
   117541 gataaaaatc ggcgggaagc ttactccacc gttttaataa ttgatagaaa taactctctt
   117601 ctgctttgat tttatactcg cttaatatca atccaaaact attcgttttt tttgaagcta
   117661 attttttata aatatccaat gctttggttt tatcttcatt gacaaagagt gtttttactt
   117721 caatataaga accctcgata ttttgtgttt cttcgataaa atagatgttt tttatatatt
   117781 ccttcatagt gattcctcca aagaagtctt ttatttgata agtttactct accgaagagt
   117841 tgttaataat ccgtgaacaa aaagtaattc tttttccaat agttgttaaa ggttttttat
   117901 tttttatagt attttttgtt atttaagaaa ggaataaggt taaacaaata acaggttgct
   117961 ttttgggtct ttttccgttc aagaaactga acgaagaaaa gggaaagttg tctcttttgt
   118021 gataagagaa atcataataa acgaatgact tactttccaa taaattgaga acagtcagaa
   118081 ccagacaaat tagttgcatc tgatgaataa agtgattatt ctatgacatg aggtgataca
   118141 gatgaaatta gaagtgacaa aagaagcaca agaagtattg aagaataaat tagaagcaga
   118201 cgatcaactt ttattagata tcgaaaacgg tgacggtcca tttgcagaaa gccaagtcag
   118261 ttgccaattg gatacggcat ttcgattgat cattgtcaaa aaagatacac aaacagatct
   118321 aagtctttat tctgtagtgg ctgatacacc agttggacca atcaaaatca aagacagtgc
   118381 aatactttac atggatgatc catccacact tgctttagaa ccaacttata atagtttaca
   118441 attaaaagga ccaagcggct tgagaaaagg caacttgcaa gttgttcgaa aagactagag
   118501 ggataaaatg ggaaaattgg cgatcatcag cgacctacat gtggacatca ataaattcgg
   118561 cgaatcagag ctgatgcagc tttggcaagt tttgcaaaag cacaagatca ctcggcttca
   118621 tctagccgga gatacggcta ataaagtaga ccgttgccta gctgttgtcg aatttttcgt
   118681 caataaagga ttatctacga catttcattt cggcaatcac gagttggcag atgtgcccaa
   118741 tgaacagatg atggaccatt ttccagaccc acatttttta aatgaacggt atattgcttt
   118801 aaatgagcag accgttcttt tagggatgaa tggctggtac gactatcagt tttccgaatt
   118861 gaaagattac gaggcaatcg tacgaatgaa gcgtttgtat tggtatgatc ggttcatcca
   118921 gcgtgggaaa acagatctcg aggtcaatgc agaaatgctt gcagctgcaa aaaatttgct
   118981 agaccagctg gaagcaaaaa aacttgaggt gattttatcc actcatttcg ttcctaaacg
   119041 ggcatttatc atgtatcaat ctgctcctta tgagcgttgg aacaaattaa atgcattttt
   119101 aggatcagaa tcattcggag aattacttga ccgttattca aatatcaaac aagtagtttt
   119161 tggccatacg catcgtcgct ttgaagataa atccatcggt cacacgattt acagctgcag
   119221 accttttggt tattattatg aatggcagct gacccgagat tttgtcttga aagaacagtt
   119281 gctagacagc tatgatccta tgaaattacg tgtcctcttg cgtgcccatc acccagcttt
   119341 tcaggcctat caaacacaac atttgcaaga ggaatttgaa caagcgatga caatcgttcc
   119401 gtattgagac agcattagta atgtgtaaaa gaaaatacct tgtaaaacat aaggataagt
   119461 aagagcagta gatccattta tcgtggatat gctgcttttt ttgcggaaaa taatcagcga
   119521 atgtttattt gatcggatga tttgtaactc gcagagtact agatgcaagc gtgtattctt
   119581 tttttgaacg ataatcacaa aaaaaaatat aatatacatt ttttatttaa ttataattaa
   119641 tattgattga agtctaggca gtcaagtcac attttgatag ataggagggg gacttacgaa
   119701 ttattttaaa ggctatgaca gctgtatttc tagattgtgt ttgcatcaag ttgcaataaa
   119761 aactagaaat caaatcgggc tgataatcat ttataactaa tcgatacata ggaccaaata
   119821 taggtctatg ttcttttatt tcataagtat cgtaaaacag aattttgcta tggattaatc
   119881 caatcgactg atatgtttag taaataaaga aagaggaatg tcaatgatga aaaaagaaat
   119941 cgtattaaca gcagcaatga tgttattcag catggtagca agtacgactt ttgtttctgc
   120001 aactgaagta tacccaaagg aatataacac agaaggaacg attacatttg aagcaggaga
   120061 tgagggtgta actcctcctg ttgatccaga gaatcctgat cccaataaac ctgtcgatcc
   120121 atcagatcct ccaagccctg gaacaggagg ggcattatcg attgattatg gatcaaaatt
   120181 caaatttggg actcaaaaaa tttctactgc ggataaaacg tattatgcag ctgctgatgt
   120241 gatgaacgat gggtctagaa aaccgacata tgtccaagtg acagatagga gaagtacctt
   120301 atctgggtgg aaattaagtg tctctcaacc agaacagttt aaaactgcca gtggggatga
   120361 actagttgga gcacagctga aatttacgaa agggcaggct gtttctttgg ttgatccaac
   120421 atatacgccg caaacggtga attctgaatt aacgttgaca ccgggaggaa acaatacgtt
   120481 agcaattaat gctaaatcag gaacaggtgt ggggacttgg gtctatcgat ttggtgcaaa
   120541 tgaaaatgaa aatcaagatg cggtacagct ttcggtaccc ggtaaatctg tcaagttagc
   120601 gcaacaatat tccactaaat tagtttggac attagaagat acacctaaca actagtttac
   120661 tgaaaagaac tgttaaaaat aaatacgtag tcatattgtc ttgcgaggta atcgagcaaa
   120721 aattgtcaaa ggctaggcta aatttgtttg gatacgaata gttcatctag gaatttaacg
   120781 atcaggagga aaagatatat tgaaaaagag gaggatcgtg ctcattttaa gcagtctctt
   120841 agtgactaat atctttccga tcatagggta ctctttggaa ttgaatcagt tggagcatgg
   120901 aaatagaaga gacgaagaaa gcaaactcac ttcgacattc gacagtttaa tagaatccaa
   120961 ccagacacaa gaaagcagtg aggatttaag tatttcgagt agtggagaga ccactgacaa
   121021 cgtagaagct gagggttcgg acaaacaagg actagaagat gcaccaattt ctgcggttga
   121081 gctgcctgac gatcccaata ttatttctat cgataaaatt tttcaaacac ctatcggtac
   121141 tagcacgtcc atattggaaa atgggaagtt actgcagttg aacccagcag aaaggtctca
   121201 aagaggagct atttggtcaa ataagaagat tagtttactc tcggatttta catttaaatc
   121261 ttatttatac ttaggaaatc aacgagatag agcgggagat ggcatgacct ttacattgac
   121321 tggcgatcct agaatggcta gtaatcccag tcaagttatt ggatcgccag gtatgggaat
   121381 tggctcatat tctactcgtt ctggccaacc ttacattgcg aatgcgctct cgattgagtt
   121441 tgatacgtat aaaaatagtg gttcttctga tcgaatggat cgagagataa ctgctgataa
   121501 tagagggcat ggacatgtcg cttttgtcac gcctaaacca aataataata attattctgg
   121561 agagcatact ggcgtgacgg tagctcctac atttctttct aatggcacat ggcgcttgtt
   121621 aataattaaa tgggacgcgg agcaaagaag tcttacttat gatttggaag gtgtcggtcg
   121681 ctcttctcgg attatacctg atctcattag gcagtttggt tctacagaag taaattgggg
   121741 gtttacttct tcaacaggta ctttttttca agaaaatgct gtcgctgtca cgcgacttcc
   121801 atcgaatgtc acatcaacag ctgatgtaaa agtcaacgat agtgattatg gggccatcgc
   121861 tgaagctgga ggaaacgata agataactat cagaaataca ttgaaggtcg agggggattt
   121921 tcttgaatat aagaaaatgc agactagtat cgacctccca caagaattaa ctattcccga
   121981 gcatatcttg atcaatggaa atcaaattga tgccaaagat atcttgataa ccggaaatcg
   122041 agtcacgcta aatctgacag attattttat tgctggagat acgttaataa tcgaattgga
   122101 gacaactttg caggaagtaa ttcctgaaaa agtactcact atgcattttg aataccttga
   122161 aaacgggaat ttgattgagc aatcgaatga aataaaccta aagatcgcaa agctgaagga
   122221 gatagatatc catgtttatt ataaagataa agacagtcag attgatattg ctgaaatgaa
   122281 aacaatcact gggaaaatag gagagaagta taaagaaact cctattgata ttgaagggta
   122341 tgtttttgac tcggattcag cgaatacaga aggcatcttc tccgaaaata cagaggatat
   122401 ctatttttat tacagaaaag gcaaacttta tctctcaact gctcctcaat atgtcaattt
   122461 tggaaaacat aaaatatcca gtagaccatt aagtgaattc ggacagtttt caggtgggtt
   122521 gaaaattata gatgaacggg cttttggaag ttggaaatta caattgaaac aagagaaagt
   122581 tcttacaaat ggagattttg agcttccaga agctctttcc tttgttacct ctgaaaatac
   122641 aacggttata gggacatccg ctgttacgat tttcgaaagt gatcaaaagg gtgaaagcga
   122701 tttgtcctct cttttagatt ctacagctca tcgtggaatc agaatagata ttcctgtaga
   122761 aaaccaaaga atcggaacct ttgaggggaa actatcttgg atacttgcag atgtcccagg
   122821 aaattaacag gaagagaaga atataacaaa attattgagt ttcaagaagg gcacaggtac
   122881 cataggctct tgtgtcccac agagacaaga ttttgttata gtcttctctt acatatgatt
   122941 aaaggagcga ttttcttgag accaaaacaa caattattta taacactcct agttatttta
   123001 ggggcacttt ttaacaatat atcagtgtca gctagtgcat ttaatttttc agtgacgccg
   123061 ataacttcag agaatcaaat cgacaagaga aaaacttact tcgatcttca acttgatccg
   123121 gatcaggaag tagaagtaaa agcggaattg agaaatgata cagaaaaaga agtgaaaatc
   123181 gatatttctg tgaatagcgc aaccaccaat tcaaatgtga tggttgaata cggaaaaaac
   123241 gagattgaaa aagacatgag cctgatcttt gatctggtag attatgtgag ctatccacag
   123301 atagtgacgc taaaacctaa aagtgtccaa accgttgctt ttcatgtcag gatgccgaat
   123361 gagcgatttg atggtgtatt ggctggtggg atcacattcc aagaaatcca gacggaaaag
   123421 gaccaaacag aaactaagga tcaaagctta tcgattgaga atgaatacac ctatattatt
   123481 gctttgttga tgcaacagac actgaacgaa gttgctccga accttactct tcatgaagtt
   123541 aaaccagatc aaatcaatgc aagaaatgtc atcttagcaa acgttcaaaa tgatcaaaaa
   123601 acctatatca atcaagtagt tattgaaaca aaaattacaa aaaaaggaca ttctgaagtt
   123661 ttatatcaag aggaaaaaga aggattgcag attgcgccga atacaaattt ttcttttcca
   123721 actgctttaa atggtcaacc gctaacccca ggtgaatatc accttacaat gactgtttta
   123781 ggaaatgaaa atgaaaatgg aaaattttcg agaaaaaaag gaaatactac gatcaactat
   123841 accaatcaat gggtatttga aaaagatttt acaatagacg gaaaagtagc caaggaattg
   123901 aacacgacgg atgttacgat taaaaaagac aataattgga tttatatctt agtagcttca
   123961 cttttcttat tgtttatttt attatgcata cttttgtttg ttttgagaaa aaaagaagag
   124021 aaagaaaagt aaggttaaga taacaaatag taaattttta ttattgtagg atggttgggc
   124081 tctttttata acaatataaa atataccatt ttattaataa aaatgcatac tagtaaatga
   124141 tataattcta ataacaggtt tgatcgcgag aaaggccaaa taaaacgctc tccaaaatgt
   124201 taaaaaaaag acaggacgat gtatattata caaacaagaa tcgctgacaa cagtgactcg
   124261 gatccaggaa atcagtttta tccccagcta gttggtgaat gcatggaaag taatatacgt
   124321 agaaagagct gatgactaat gaattatgag ttttttttaa gcaaagaaga tcacagaagt
   124381 tattcattac ttaaatattt agaagcaagc tcaaatttat cagagtcaat atcgaatgtt
   124441 caagaagagt tgtcgctatc gacatttctc ttgaaaaaaa cgatcgataa gctgaaacat
   124501 gatttacaaa agttcgatct agagaaaaat ttgcgagtaa ccgtcagtga attggatata
   124561 tgtctggaaa ttaatggaaa atgttctagc aaagctctgt tatctcgtta tataacggat
   124621 tctttatcta tgaaaatggt attggctttc tttcaggaaa aatatatctc agtagaaaat
   124681 tttgctaaac agcatcacgt gagttattct gtggcttata aagtattaca aagactaaaa
   124741 agaaatctaa aaaaatatca aatttttttt gaaaagagaa agttg
//
LOCUS       DAFBSV010000002        99842 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.002, whole genome shotgun sequence.
ACCESSION   DAFBSV010000002 DAFBSV010000000
VERSION     DAFBSV010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 99842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 99842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..99842
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.002"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(19..729)
                     /locus_tag="LLB18_000130"
     CDS             complement(19..729)
                     /locus_tag="LLB18_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HBK5243166.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(726..2198)
                     /locus_tag="LLB18_000131"
     CDS             complement(726..2198)
                     /locus_tag="LLB18_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBK5243167.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            2336..2809
                     /locus_tag="LLB18_000132"
     CDS             2336..2809
                     /locus_tag="LLB18_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBK5243168.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(2962..3513)
                     /locus_tag="LLB18_000133"
     CDS             complement(2962..3513)
                     /locus_tag="LLB18_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBK5243169.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            3618..4148
                     /locus_tag="LLB18_000134"
     CDS             3618..4148
                     /locus_tag="LLB18_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HBK5243170.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(4631..5074)
                     /locus_tag="LLB18_000135"
     CDS             complement(4631..5074)
                     /locus_tag="LLB18_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5243171.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(5090..6250)
                     /locus_tag="LLB18_000136"
     CDS             complement(5090..6250)
                     /locus_tag="LLB18_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBK5243172.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            6757..8457
                     /locus_tag="LLB18_000137"
     CDS             6757..8457
                     /locus_tag="LLB18_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243173.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(8559..9392)
                     /locus_tag="LLB18_000138"
     CDS             complement(8559..9392)
                     /locus_tag="LLB18_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBK5243174.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(9696..11861)
                     /locus_tag="LLB18_000139"
     CDS             complement(9696..11861)
                     /locus_tag="LLB18_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK5243175.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            12121..14415
                     /locus_tag="LLB18_000140"
     CDS             12121..14415
                     /locus_tag="LLB18_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBK5243176.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKTLRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFKLLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            14408..15073
                     /gene="pgmB"
                     /locus_tag="LLB18_000141"
     CDS             14408..15073
                     /gene="pgmB"
                     /locus_tag="LLB18_000141"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBK5243177.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFTKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            15066..16073
                     /locus_tag="LLB18_000142"
     CDS             15066..16073
                     /locus_tag="LLB18_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBK5243178.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            16095..17114
                     /locus_tag="LLB18_000143"
     CDS             16095..17114
                     /locus_tag="LLB18_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5243179.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(17395..18763)
                     /gene="nhaC"
                     /locus_tag="LLB18_000144"
                     /pseudo
     CDS             complement(17395..18763)
                     /gene="nhaC"
                     /locus_tag="LLB18_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
     gene            complement(18872..20293)
                     /locus_tag="LLB18_000145"
     CDS             complement(18872..20293)
                     /locus_tag="LLB18_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK5243180.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(20536..22413)
                     /gene="tdc"
                     /locus_tag="LLB18_000146"
     CDS             complement(20536..22413)
                     /gene="tdc"
                     /locus_tag="LLB18_000146"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBK5243181.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(22704..23960)
                     /locus_tag="LLB18_000147"
     CDS             complement(22704..23960)
                     /locus_tag="LLB18_000147"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBK5243182.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(24072..24277)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            24540..25841
                     /locus_tag="LLB18_000148"
     CDS             24540..25841
                     /locus_tag="LLB18_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBK5243183.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(25910..26509)
                     /locus_tag="LLB18_000149"
     CDS             complement(25910..26509)
                     /locus_tag="LLB18_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK5243184.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            26763..27644
                     /locus_tag="LLB18_000150"
     CDS             26763..27644
                     /locus_tag="LLB18_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5243185.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            27657..29267
                     /locus_tag="LLB18_000151"
     CDS             27657..29267
                     /locus_tag="LLB18_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HBK5243186.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(29344..30003)
                     /locus_tag="LLB18_000152"
     CDS             complement(29344..30003)
                     /locus_tag="LLB18_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBK5243187.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(30286..30951)
                     /locus_tag="LLB18_000153"
     CDS             complement(30286..30951)
                     /locus_tag="LLB18_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HBK5243188.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(31098..31703)
                     /gene="dhaL"
                     /locus_tag="LLB18_000154"
     CDS             complement(31098..31703)
                     /gene="dhaL"
                     /locus_tag="LLB18_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HBK5243189.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(31731..32741)
                     /gene="dhaK"
                     /locus_tag="LLB18_000155"
     CDS             complement(31731..32741)
                     /gene="dhaK"
                     /locus_tag="LLB18_000155"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HBK5243190.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(32716..33162)
                     /gene="dhaM"
                     /locus_tag="LLB18_000156"
     CDS             complement(32716..33162)
                     /gene="dhaM"
                     /locus_tag="LLB18_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HBK5243191.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            33265..33585
                     /locus_tag="LLB18_000157"
     CDS             33265..33585
                     /locus_tag="LLB18_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBK5243192.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(33697..34566)
                     /locus_tag="LLB18_000158"
     CDS             complement(33697..34566)
                     /locus_tag="LLB18_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBK5243193.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(34662..35966)
                     /locus_tag="LLB18_000159"
     CDS             complement(34662..35966)
                     /locus_tag="LLB18_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBK5243194.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(35963..36472)
                     /locus_tag="LLB18_000160"
     CDS             complement(35963..36472)
                     /locus_tag="LLB18_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243195.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(36647..38782)
                     /locus_tag="LLB18_000161"
     CDS             complement(36647..38782)
                     /locus_tag="LLB18_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK5243196.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(38865..40520)
                     /locus_tag="LLB18_000162"
     CDS             complement(38865..40520)
                     /locus_tag="LLB18_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBK5243197.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(40522..40836)
                     /locus_tag="LLB18_000163"
     CDS             complement(40522..40836)
                     /locus_tag="LLB18_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBK5243198.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            41006..41266
                     /locus_tag="LLB18_000164"
     CDS             41006..41266
                     /locus_tag="LLB18_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBK5243199.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            41280..41594
                     /locus_tag="LLB18_000165"
     CDS             41280..41594
                     /locus_tag="LLB18_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBK5243200.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(42324..42878)
                     /locus_tag="LLB18_000166"
     CDS             complement(42324..42878)
                     /locus_tag="LLB18_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBK5243201.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(43004..44933)
                     /locus_tag="LLB18_000167"
                     /pseudo
     CDS             complement(43004..44933)
                     /locus_tag="LLB18_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(45239..45955)
                     /locus_tag="LLB18_000168"
     CDS             complement(45239..45955)
                     /locus_tag="LLB18_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBK5243202.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(45956..47779)
                     /gene="glpO"
                     /locus_tag="LLB18_000169"
     CDS             complement(45956..47779)
                     /gene="glpO"
                     /locus_tag="LLB18_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HBK5243203.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(47793..49289)
                     /gene="glpK"
                     /locus_tag="LLB18_000170"
     CDS             complement(47793..49289)
                     /gene="glpK"
                     /locus_tag="LLB18_000170"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBK5243204.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(49425..50885)
                     /locus_tag="LLB18_000171"
     CDS             complement(49425..50885)
                     /locus_tag="LLB18_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5243205.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(50875..52170)
                     /locus_tag="LLB18_000172"
     CDS             complement(50875..52170)
                     /locus_tag="LLB18_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBK5243206.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(52502..53179)
                     /locus_tag="LLB18_000173"
     CDS             complement(52502..53179)
                     /locus_tag="LLB18_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HBK5243207.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(53209..54300)
                     /locus_tag="LLB18_000174"
     CDS             complement(53209..54300)
                     /locus_tag="LLB18_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HBK5243208.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(54401..54835)
                     /locus_tag="LLB18_000175"
     CDS             complement(54401..54835)
                     /locus_tag="LLB18_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK5243209.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(55419..56876)
                     /gene="ascB"
                     /locus_tag="LLB18_000176"
     CDS             complement(55419..56876)
                     /gene="ascB"
                     /locus_tag="LLB18_000176"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBK5243210.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(56873..58768)
                     /locus_tag="LLB18_000177"
     CDS             complement(56873..58768)
                     /locus_tag="LLB18_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK5243211.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(58826..60601)
                     /locus_tag="LLB18_000178"
     CDS             complement(58826..60601)
                     /locus_tag="LLB18_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBK5243212.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARLPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(60651..62147)
                     /locus_tag="LLB18_000179"
     CDS             complement(60651..62147)
                     /locus_tag="LLB18_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBK5243213.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(62341..63963)
                     /locus_tag="LLB18_000180"
     CDS             complement(62341..63963)
                     /locus_tag="LLB18_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBK5243214.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(64291..65604)
                     /locus_tag="LLB18_000181"
     CDS             complement(64291..65604)
                     /locus_tag="LLB18_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBK5243215.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(65849..66073)
                     /locus_tag="LLB18_000182"
     CDS             complement(65849..66073)
                     /locus_tag="LLB18_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243216.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(66093..66515)
                     /locus_tag="LLB18_000183"
     CDS             complement(66093..66515)
                     /locus_tag="LLB18_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HBK5243217.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(66658..67368)
                     /locus_tag="LLB18_000184"
     CDS             complement(66658..67368)
                     /locus_tag="LLB18_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243218.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(67386..67883)
                     /locus_tag="LLB18_000185"
     CDS             complement(67386..67883)
                     /locus_tag="LLB18_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5243219.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(67920..68372)
                     /locus_tag="LLB18_000186"
     CDS             complement(67920..68372)
                     /locus_tag="LLB18_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK5243220.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(68507..69112)
                     /locus_tag="LLB18_000187"
     CDS             complement(68507..69112)
                     /locus_tag="LLB18_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBK5243221.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(69562..70182)
                     /locus_tag="LLB18_000188"
     CDS             complement(69562..70182)
                     /locus_tag="LLB18_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBK5243222.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(70184..71053)
                     /locus_tag="LLB18_000189"
     CDS             complement(70184..71053)
                     /locus_tag="LLB18_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HBK5243223.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(71076..71483)
                     /locus_tag="LLB18_000190"
     CDS             complement(71076..71483)
                     /locus_tag="LLB18_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBK5243224.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(71502..72791)
                     /locus_tag="LLB18_000191"
     CDS             complement(71502..72791)
                     /locus_tag="LLB18_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK5243225.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGDFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(72818..73120)
                     /locus_tag="LLB18_000192"
     CDS             complement(72818..73120)
                     /locus_tag="LLB18_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5243226.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(73145..75238)
                     /locus_tag="LLB18_000193"
     CDS             complement(73145..75238)
                     /locus_tag="LLB18_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBK5243227.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(75727..76491)
                     /locus_tag="LLB18_000194"
     CDS             complement(75727..76491)
                     /locus_tag="LLB18_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HBK5243228.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(76602..77471)
                     /gene="mdcB"
                     /locus_tag="LLB18_000195"
     CDS             complement(76602..77471)
                     /gene="mdcB"
                     /locus_tag="LLB18_000195"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HBK5243229.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(77496..78572)
                     /locus_tag="LLB18_000196"
     CDS             complement(77496..78572)
                     /locus_tag="LLB18_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HBK5243230.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(78596..79189)
                     /locus_tag="LLB18_000197"
     CDS             complement(78596..79189)
                     /locus_tag="LLB18_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HBK5243231.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(79193..80870)
                     /gene="mdcD"
                     /locus_tag="LLB18_000198"
                     /pseudo
     CDS             complement(79193..80870)
                     /gene="mdcD"
                     /locus_tag="LLB18_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
     gene            complement(80860..81159)
                     /locus_tag="LLB18_000199"
     CDS             complement(80860..81159)
                     /locus_tag="LLB18_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HBK5243232.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(81261..82907)
                     /gene="mdcA"
                     /locus_tag="LLB18_000200"
     CDS             complement(81261..82907)
                     /gene="mdcA"
                     /locus_tag="LLB18_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HBK5243233.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(82914..83825)
                     /locus_tag="LLB18_000201"
     CDS             complement(82914..83825)
                     /locus_tag="LLB18_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBK5243234.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            83945..84802
                     /locus_tag="LLB18_000202"
     CDS             83945..84802
                     /locus_tag="LLB18_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK5243235.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(84989..85351)
                     /locus_tag="LLB18_000203"
     CDS             complement(84989..85351)
                     /locus_tag="LLB18_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HBK5243236.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            85697..87136
                     /locus_tag="LLB18_000204"
     CDS             85697..87136
                     /locus_tag="LLB18_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5243237.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(87143..89695)
                     /locus_tag="LLB18_000205"
     CDS             complement(87143..89695)
                     /locus_tag="LLB18_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBK5243238.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(89809..91140)
                     /locus_tag="LLB18_000206"
     CDS             complement(89809..91140)
                     /locus_tag="LLB18_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK5243239.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(91106..92584)
                     /locus_tag="LLB18_000207"
     CDS             complement(91106..92584)
                     /locus_tag="LLB18_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK5243240.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(92889..94724)
                     /gene="tdc"
                     /locus_tag="LLB18_000208"
     CDS             complement(92889..94724)
                     /gene="tdc"
                     /locus_tag="LLB18_000208"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBK5243241.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRCSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            95194..96621
                     /locus_tag="LLB18_000209"
     CDS             95194..96621
                     /locus_tag="LLB18_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5243242.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(96713..97078)
                     /locus_tag="LLB18_000210"
     CDS             complement(96713..97078)
                     /locus_tag="LLB18_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBK5243243.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(97075..97440)
                     /locus_tag="LLB18_000211"
     CDS             complement(97075..97440)
                     /locus_tag="LLB18_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBK5243244.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(97632..97880)
                     /locus_tag="LLB18_000212"
     CDS             complement(97632..97880)
                     /locus_tag="LLB18_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243245.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            97879..98007
                     /locus_tag="LLB18_000213"
     CDS             97879..98007
                     /locus_tag="LLB18_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HBK5243246.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            98064..99758
                     /locus_tag="LLB18_000214"
     CDS             98064..99758
                     /locus_tag="LLB18_000214"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HBK5243247.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
BASE COUNT        29149 a        20971 c        17299 g        32423 t
ORIGIN      
        1 tacatggtgt tcaaaatatt attcgccttt tgcttctttc actaattttg cgaatgcttg
       61 ttgttggaat tcagcagcta aggctttcgt acgttgttct tgctctgctt tgctcatttt
      121 tggattttca gtcattgctt ttaccatacc gtcttgaaca taagcttttg cttcactttc
      181 catcgtactt tgctgtttct tcactaattc agctaacttg gctgcttggt ccgtacttaa
      241 ttctacccat gtctctggga ttttgaatgt attcactcgg ctgtcatatt cgtgattgtt
      301 atcagcaata ttgaaccaga atttatacat gtcgtttttg tattcccaat aagtagtttt
      361 cgtcactttt tcagcatcgc cgtctgtctt ttctacttta tttgtttcgt tatccgtacc
      421 agttgctttt ggtttttctt gtttttcatt tgttcggtaa agatacactt tttcttttcc
      481 attccctaaa gctttataca aaagcatatc tgctccttgg gaatcagcac tggaaacaat
      541 tttttctgtt tttgtttccg ttactttttc cattccaaag tgattggaca aattagcgac
      601 gatcaaactt agtgaagcga cgaagattag tccgaaaatc aaagataaaa aggtttgcca
      661 tgttttttta gcgaacacgt tcgttaaagc aaaagcaagc aagctgacaa tcaaaactcc
      721 aataatcatg cattatcccc cgctttcatt agaacaggtt cttttttctt caataaaaag
      781 gcaataataa agccaagaat cccaaagatg atcgctacga taaacgcggc atggtaacct
      841 gacagtgtgg cattgattgc ctgatcttta taagctaatg gcgtattatc caatacagat
      901 ttgcttggga tatttgcttt tgtcacattc gtcaacacac tgatcaaaat agctgtacca
      961 atcgagcttg cgatttgacg gaatgtatta tttaccgctg tcccatgact gatcaagtta
     1021 tttggcaatg cattcatacc agaagtcgtt accggcatca tgaccatgga gatcccaaac
     1081 atacggatcg cataaaggat cacgatatat aaaactggag tcgtttttgt caagaaagca
     1141 aatggtgcag ttgccgctgt caaaatgaac atccctgtga tggctaaacg tttcgcgccg
     1201 tatttatcga aaatcgcacc cgtcacaggc atcatagccc ccatgatcaa tgcacccggc
     1261 aacaacatca agccagaatg gaatgctgat tctccacgaa tattttgaat atacaatggt
     1321 acgaccattt ctgcccctac catcgccata tttgttacac cagctaaaac agctgcaatc
     1381 gtgaatgtag atgatttgaa tacacgaagt tccaagaatg gatgttccaa atgtaattga
     1441 cgccatgaga acaaggcgat gaaaatcaca ccaacaacta agaaaccaat tactttcaag
     1501 cttccccagc cgtcatctcc tacactagaa aatccgtaaa gtaaactacc gaatccaatc
     1561 gttgataaaa tagcggataa aatatcaatg ctaggatttg acaatggaat aacacttttc
     1621 attaggaaga atgctaaaac caagacaaga acaacgattg gcagtaccat accaaacaag
     1681 tcacgccaat ggtagttatc aatgatataa ccagataatg tagggcctaa agcaggagca
     1741 agtccaataa cgatccctga catccccatt gctgatcctc ttttttctgg cgggaaaata
     1801 gatagcatga tattttgcaa taatggcatc gatactccca caccgcaagc ttggatcaaa
     1861 cgaccgatta gtaatgtact aaaattaggt gctgtaaagc aagtaatcgt tccgatcaaa
     1921 aagatcgtca tggcagaaag atataaattt cttgaactga atttattgat cagccatgct
     1981 gttattggga tcatgatccc gttgactagc aagaaaccag tcgttaacca ttgcacatca
     2041 gacgctgaaa tatcgaaagc tttcatcaat gtaggaaaag ctgtcgtcaa taaggtctga
     2101 ttcaaaacgg tacaaaatgt accaattaat aagacaacaa ctaaaagtgt ccgattatat
     2161 ggttttccgt aaatatctac gggttggttg ttactcatat ttctccttct ttctgaattt
     2221 tttctgaaac tactagaata ctttagtcct aaattcgcta tttgtcaacc tacttgacac
     2281 ataagttaat acggatataa ttaagggaag caagaggaca aaaggagtga caaaaatggt
     2341 tggggcttcc cttaaacgtt tgttggaaaa tgatcaattg gttgttggca tcagtgaatt
     2401 aagtgatatc gtaggtgtgt ctccacgtca attaaggtat tgggaacaaa agggattcat
     2461 tcgttcgatc gaagctgatg cgaattgtcc tagaaaatat cgtttaccta cagtcataaa
     2521 agtagaactg atcaaaaaat atttagatga cggatttact ttgtcaaaag ctgcagaaaa
     2581 ggcagaaatc cgccaaaaga aaatgcacca tgtccgtaaa gttttttcaa aagcaatcaa
     2641 agatatcgaa ttgatcgacg aacgctatac gattttacaa atcggtaact tcaaagaaga
     2701 gaatgctaag atgtacatca ttcatgacaa cgagacagac gaattaactt acaagctcct
     2761 tcctgtcgat gaaaaagctg actacgaaca gttgttaaaa gaactctaaa cgccactaat
     2821 ctcctaagta ccaagctttt taataagtag atgctacata aatacttgaa aaaaggcctg
     2881 tttgaacata agaatatccg aacggtgatc tgcgtttctt tcatatagaa aggaattctc
     2941 catcactgtt cggatatttt tttatttttt tcggttactt tcttctaata catctgttag
     3001 ccaatttgca tattctgttt cccgattgat cgcatgcgct aaaatcaggt agtgtccgta
     3061 attttcatgt ttttcttttt cagtaggaaa gatcgttttt tttcgctcta atagatgaag
     3121 tcgtttttct tcatgaaggt cacgctgctg ctgaataatt tctactaatg ccggatcatt
     3181 cacgtctttg acgaaataca atttcagaac aaattcgtct cgattaaccg gtagttcatt
     3241 ggtgggtgta tgaatccact ctgccaattg ttccttccct tcttctgtta attcataaac
     3301 tttcttttcc aatttttcac ctgtgatctc tacttgatgc tgaatgattc cttgctcttc
     3361 catttttgca agttcaggat aaatctgact atgttttgct tgccaaaatt ctcctatttc
     3421 atttttgaac gattgattca attcatatcc tgtcatcttc ttcttactta ataaccctaa
     3481 caaaatatat cgaagtgtat tttttcttgc catcagtttt ccctccttga caaatcttta
     3541 aatccattct atcataaatg agtaatcgaa aacatgtagt ttattacatg ttttaattta
     3601 taaggagatg cttaaacatg aaagaattta aagaattgga agattttatt ggaactcact
     3661 ttatctatac gtatgacaat ggttgggaat atgaatggta tgccaaaaat gaccatactg
     3721 ttgattaccg tatccatggc ggaatggtca aaggccgttg ggtaaaagac caagaagctg
     3781 atatcgttaa attgacggac ggcgtattca aaatcacttg gacagagcca acagggacag
     3841 acgtggcatt ggactttatg ccaaatgaaa agaaacttca cggaatgatc tttttcccta
     3901 aatgggttga agaacatcca gaaatcactg ttactttcca aaacgaacat atcgcagaaa
     3961 tggaagcagc tcgtgaaaaa tatgaaactt atccaaaatt acttgttcct gaatttgcta
     4021 cgatcactta tatgggtgat gcaggtatag acaatgaaga tgttattagc gaagaaccat
     4081 acgatggaat gccagatgat atccgtagcg gaaaatactt cgatgaaaat tataaacgag
     4141 taaaataagg ttgtgaaaga gaggttgtga aatcagcgtt ctgacctgag tattagagaa
     4201 agaaacggaa aaatagttcc tcatgttttg ccgttttttg agctaatacc gagggtcagc
     4261 tgattgaaca ccgtttatca agaggttgtg aaatcagcgt tatgctttga gtaataagaa
     4321 cgctagttag aaaatagctt ttcatatttt ctaggctagt gggcttatta ccgagaagca
     4381 gccgtttgaa caccgtttat caagaggttg tgaaatcagc gttttgacct gagtattaga
     4441 gaaacaaatg gaaaaatagt tcctcatatt ttgccgtttt ttgagctaat accgagggtc
     4501 agctgattga acaccgttta tcaaagattg taacaactgc atattcacac agttaaatta
     4561 gtgacttcaa aatgaaataa tgctcccagc aaaaaattag gctgggagca ttatttcgtt
     4621 attctgttca tcaaaaatca gcgttttgat tccatttcat cacaagttcc tcctcattta
     4681 ctgcttcatc tttttgctgt gtttgaattg taaaaccttg tgaaagatag aaatgaatag
     4741 ctgattgatt tttttgatag actgtcaaag tcagtgtttt attggtttct tttatttttt
     4801 tcattagttg cgtaccgatt ctttgttgcc ggtattccct tttcacaaag attcctgcga
     4861 taaactgatc aatcacccca gcaaaaccaa taatttcttg atctatttct gctaagtaaa
     4921 tcactgcatc tggtaaagct ttcctaacag attctacttg attctcccaa taagttgatg
     4981 gaatgaattc atgagaatcc aagttagcat gcagccaaat cgatagaaca gattccagtt
     5041 ctttggcaga caattttgtt gttgtgcgga tcattttttc tctccttact tattcattga
     5101 ttttaaaata aaaaccattt ttttgaagct cttttacaag ttttcgcccc tcaaaaaagt
     5161 atatcttctc ttgttttact tttctaatac caaaagaaac agcaacttta ggatcatcag
     5221 ctgaaacgat tcgataagtt ccaccaggca attgatccag cttgactttc ccatgatggt
     5281 cgctttgtac tgaaaacggc acaccatttc tagtaagtgt ttttttctta tgtttcaaaa
     5341 tgaatgaact accatttacc ggtttccctg acgaatcact aataataaat gaaaaatcaa
     5401 gcactttttt acttaatcta tactgataga ttagtcgtcc gataaacact aacagtatga
     5461 ctacagctat tatcgttcct gcaagaataa accattgccg catggttctt tcctgatttc
     5521 cttttccttc ttcttttttt accgattcgt tataaggaat ccgatgtcct gtcactagca
     5581 aacgatgcgt gttgatcata tacggcgtac atgtaagcaa ggtaactaag tcttctcctt
     5641 ctgaaatcgt tagaacagac gtgtcatctg gcagtaccac ttgtatattt ttaacttgat
     5701 aagccaattt ctcccccaaa acagtcaaaa taaacgtgtc tccgttttct aaacgatcta
     5761 attcggtaaa taaccgtcga ttaggtaaac cgctgtgagc agagatcact gaatgcgtcg
     5821 aatttccacc aagcgggaaa gaggttcctt gcaagacgcc tgctccattt tcaaggatcc
     5881 taccattgag ccgatcataa agtgaaatat ttaattggat cttaggtata ttgatacttc
     5941 cgatcagcca ttcctctaat tggctggatg ttgtactttc atttctgttc ttttcattga
     6001 aaggatcagt accaggattg aatccttggt cagttaatcg ttggtttttc tcctccattt
     6061 tctttcgctg cacttcaatt tcagctgcgg tccgtttttg tacttgttcg atacgttttt
     6121 gatcaataaa actatttaaa gaatccacat aaaatggata taaagcgatc agtaacccta
     6181 cgacgataca tattaataaa aacaaacgaa acaaaagtcg acgagactgt ttttgcttac
     6241 tctgcttcac atgtgtcctc ccttgcaagt ttttttgttc tttcttttat tatatgggtt
     6301 caggaaaaaa atagaaaatg aaagccgatg aggttgtgaa aaagctgtcc tgcatcaagt
     6361 aataagtaca gcccaaaaaa atagctactc atattttttg ttgggttggg cttattaccg
     6421 cagatgcaag cttttgaaca ccgtttaagg aagaggttgt gaaaactgcg ttatgctttg
     6481 agtaataaga gcgctagtca gaaaatagct tctcatattt tctaggctag tgagcttatt
     6541 accgagaagc agctgattga acaccgttta ccgagaggtc atgaaaaagc tactttgttt
     6601 cgagtattaa gaaaaattct gtttcaaaac aaggagatgc aacaaaactt atgtcgcatc
     6661 ctctctcctt agaactttca cttatgtttt tcttgtaaaa ttcataaata ttttcatgaa
     6721 ttttctaatt tcttgcctac ctctcgcata ggatatatga tgaatttatc taaagtttgc
     6781 aaaggagttc gacaattgaa aaaatatggc ccatttttag caattttttt cattgctttg
     6841 gcatttctca tgcctcattt attcacacat aaactaattt tgggtgctga tgccccattc
     6901 cattacaatc ggttctatga tgccgcgcaa caaattaaat atggggattt ccattatttt
     6961 ccttcccttt atggattcca gcaaagtggc aggatcgtga atgccgttta cggcccattt
     7021 ttcgcttatt tacaaggatt gatcgtgttg cttgcaggta gctggtttca ttatcagatt
     7081 ctttcaaatt tcattcttta tcttatttca ggattttcta tgctgatttt actgagatat
     7141 gtcaatgttc gaaattgggt aagtgtacca gtagccgttt tattcatgag tacgtattct
     7201 attcaatact ggtctatcaa ccaaggattc actagctggg ggacttgttt ttatccttta
     7261 tgtatgatcc ctattgctga tttcgtcctt cataaaaagt tccctgttat caaagtcgct
     7321 gtctcagtgg gacttatgac acagatccat ttactgtctt cgatcatgtt agctttgatg
     7381 tatatccctt tttatcttta ttactttttt aaccagactg aaaaaggaaa agcactgctt
     7441 caactgatta agtcggtctt gctttatttt gttctgacag caaatatttg ggcaggatta
     7501 gctattgttt acagtgggaa taagattctt cctccctttg ttaacagaga aatgagtcaa
     7561 aaggcgatag atctggatgg cagttattgg ctccattacc ctaaggcctt tcctatattg
     7621 atattatcag gttttttgct ttttattttc tttcaacaaa agaacacctt attccaaaaa
     7681 atcgtgttgt acacaagtct tgttttcttt tttctttcta ctagcttgat tccatggacg
     7741 acattgatcg aaaaaaatgt gccttttatt agtttgatcc agtttccatt tcgatttttc
     7801 gtgccattta cgctattgct tctactttac cttgcccttt cactgaacca gtggtctgaa
     7861 caaaagtggt tccgtctttt aagtatattt ggcattctta ttttttcagc acagacgatc
     7921 cagaacttat accagcatct ggaaaagtgg gaaaatgaaa catttgtcag tcgacatact
     7981 tatctattcg atacgccgga agaagcaagg aaaacattct tcagcaaaga tatgtctacc
     8041 agcttgttcg ttttccaaaa aaccacacct gactatctgc caatctataa ggagacaaaa
     8101 gacaataaat acgaccggta taacgaagaa atactagaaa acgaaacaac ttttataaaa
     8161 acacatccag gcggtctttt gacaatcaag tggaaaaaca ctggggacaa aactgttcat
     8221 atccctgtta tcgtctacga tcggactgtg ctacagcaaa atggaaaaac attgactgat
     8281 tatgaagtaa cagatatcgg gaccccaatc gtgaagcagc aaaaaggaat caacgagctc
     8341 acgcttcatt atcaaacgcc aatctatttc tatttcattc tttctcttac tttgattggc
     8401 tggtttacct tgctatgttt atttatttat catagataca agcttttacg tgcttaggca
     8461 aaagggataa atacatccga tcaaaaaact ctccaaacgg tataatcgtt tggagagttt
     8521 tattttaatc agttttttta tgttatatgt tatatttttt attcgttcac atctaattcg
     8581 atttccaccc cgtagtgatc actgatgatt ggactatcga tcccatcaaa aatccgttga
     8641 tattttttaa cctgcattcc ttcagggacg aaaataaaat ctatacgcaa tttttctgta
     8701 ttttgttccc aaccatctat tttcttttcc acagtagctg cttttccttt ttcattcgcg
     8761 acaacatacg aatcttgaag aagaaggcaa ctttctctta cagtataata accttgagag
     8821 tctactggat tattgaaatc acctaggaaa aaaagtggta cgcgagtttc caaaaagtag
     8881 ttttccaagt ttttccactc aaaataaaag ccactttttt tatctgtcca ccaagaaaag
     8941 tggcagctcg agacaaaaat gtcctgatca tctatctttg ttttcccaat caagatcttg
     9001 cgtgtctgat aatcttcttt cttttgaaat tgggagacgg taaggacctg actttccaat
     9061 gtttttttcg taagcagtgc atttccttct tcatatttat cataaccgat gtggctcatt
     9121 tcccaactcc aaaaatactc ttttccgtgt tcctttaaaa gctgaactaa acggtaggca
     9181 aaattatctt tacggatagg tacttgattc tttaccggac agaacttcat tagcttcgca
     9241 ggttctactt cttcagattc cagtaattgg ttgatttctt gtaaagcaat cacttcataa
     9301 tcttctaaca ggatcttatc tgctaattct tgcaattttt tctctggttc tggctcaagc
     9361 cagctatgcg tgttgagtgt catgaatttc attggttttc tccttgtctt catttcgaaa
     9421 caaaagggtt gtgacaaaat ttttgtcaca acctctccag caaatagtgt tctcctgcta
     9481 actcctcagt aataagctca atggaccagg agctattttt tgtttggctg tttttatcac
     9541 ttggtgcagg gcagcttttt cacgacctct ccactaaaca gtattcaaac tgctgcttct
     9601 cggtaataag cccaaccaaa cgaaaaatag gaggagctat ttttgtttgg ctgttcttat
     9661 gacttgatgc aggacagctt tttcacaacc tctccttaca ttttaatgga gccgatcact
     9721 ttaccagctg tcactgtacc taattgcttg atcactactt cttctacttt atcgtttgta
     9781 aatacgatca tgatcgttgg atctttttct tcgttttgga tcacatcaag atccatctca
     9841 gctaatttcg ttcctgttcc tacttcttgg ccttctttga cagcaatctc aaaagctggc
     9901 tgattcattt ggactgtatc gattcccata tggatcaaaa cttcgatacc atctttcgtt
     9961 tccagcccaa ttgcatgttt gctagggaaa atacttgtca cttttccagc gatcggcgca
    10021 acaacttctc ttgatgttgg aataacagca aagccgtcac ccatcatttt ttgtgagaat
    10081 accggatctt ttacttcaga taaaggaatc acttctccag aagctgcgga aactagttct
    10141 tgttctatac ctaagtattg cttactacct gcttgtccat ttcctgtaga aaccatttct
    10201 ggctctggaa tctctgctcc tgattgcagc agatcttcga tatctgattt caagacatct
    10261 gcttttggtc cataaactgc ttggactcca ttgtctttga cgatcaatcc catcgcccct
    10321 gctcgtttcc aggcttcttc agtccctact ttttctcgat catttacact tacgcgtaac
    10381 cgagtcatac aagcatcgac atctttgata ttttcttttc ctcccagcaa atgaatgatc
    10441 tggaccactt gctgatctgc tgttcctgtt ccgctgttag atacaacggt ttcttcactg
    10501 tcattgtcgt aatttccgtt acgtcccggt gtagcaaagt tgaatttttt gatcaagaaa
    10561 tttgctaaga aatacgtaac aacaccaaaa gcgatcacac acaacacgaa gttgataaga
    10621 tctccaccta gacccgcttt gatagctaac ggtgtccgag tcagcaattc gatattccca
    10681 aatgaatgga cccgcaatgg caagatatct gccatcgcaa atgcagcccc ttggatcact
    10741 gaataaatga catataatgg cacagcagca aacataaaca tgaactccaa tggttctgtt
    10801 acacctgtta gaaagacagc caacgctgct gaaaaataca ttgatttata tcttgctttc
    10861 ttatcaggat cgacattacg atacatcgca aaagccattc ccatcaagat acctgaagaa
    10921 ccaatcattt gtcctacttt gaaacgagcc ggcgtccagt tatgcaacac aaactcatat
    10981 tgcgacatat cccctgcacc tttaagattc actaaatcag tggcccaagc caaccataac
    11041 ggatcttgcc caaatacttg tgtccccgcc tgtgcgcctg ataaaatctc atacgatccg
    11101 ccaagctgtg tatagttgat aggaatcgtc agcatatgat gcaatccaaa tggcaatagt
    11161 aaacgttcta atgttccaaa taaaaacggt gctagaatcg gtgcgctttc ttgtgattct
    11221 gcaatccata aaccaaaatt attgattcca gcctgtacgt ttggccacac cacagcaaga
    11281 atcaatgcca cgattgttga ccataagata acaacaaacg gaacaaagcg ctttccattg
    11341 aaaaatgaca aagcatccgg caattttcta taattatagt acttattata agccattgcc
    11401 ccgacaaatc cagcgatgat ccctacgaat actcccatat tcaaagctgg tgcttccaat
    11461 acacttgtaa aaaatccttt aaccatgatc ttcgtaccga acagagtgtg ggtaaatgca
    11521 tcttcattcg caagcatgtc acttgtgaca ccaaagatag ccccagtgat ccgattgatt
    11581 aaaataaatg agatcccagc tgcaaatgct ccgcctgctc tttcttttgc ccaacttcct
    11641 cctattgcta aagcaaataa aatatgaaga ttaccaataa ttgcccaacc aatattttca
    11701 attactccgc ccgttgtgac aagcggcgtc caatcaggat tgatcaaggg aattgatttc
    11761 cctatactga tcatcaaccc agctgccggc ataactgcta ccacaaccat taaagccttt
    11821 ccaaattttt gccaaaactc aaaactaaat atctttttca ttccgtttag ctcctttacg
    11881 caatcggttt cgttaaacgt attatagcgt gcgttttctt ttttgtaaat gctttatttt
    11941 ttatttttct gtctatacca ttctataaaa cctataatac gtgtgttccc ttctataatt
    12001 ttctcctaaa aatttatttt tttaagcttt tttctatgaa atattttctt ttgtctattg
    12061 acttgtgcaa tcggttgcgt ttattatgaa cgtataaaac agctcattag gaggagaaaa
    12121 atgaaacaga tcaaacgact atttgctatt gatccatgga aaatcagcac gacacaatta
    12181 gataaaaaaa atcttcgact gcaagaatct ttaacaagta ttggaaacgg ttatatgggg
    12241 atgcgcggga actttgaaga aacttactca ggggaccacc atcaaggtac ttatttggcg
    12301 ggtgtctggt atcccgataa gacacgtgtc ggctggtgga aaaatggtta tccagaatac
    12361 tttggaaaag tgatcaacgc cttgaacttt atcgcgatag atatttcgat caacgatcag
    12421 ctgatcgact tggcttcttt ggaaccagaa gacttttact gggaattaga tatgaaaaat
    12481 ggtgtattat ctcgtacatt cacaatcact acttctacta ataaagtacg catttccttc
    12541 gaacgttttc tgagcattgt caaaaaagaa tcagcttata tctatttaac tatagaaatg
    12601 cttgaaggta gcggaacagt caaactcgta tcaaaattgg atggaaatgt tcaaaacgaa
    12661 gacagcaact atgatgaaca tttttggaat gagattgatc gtggaactat agaagaaatc
    12721 ggctatttga cgactaaaac tattccaaac aactttggga ttgaacaatt tactgttact
    12781 gcagcaatgc gccatttcgt taatggaaaa tcagtcatcc ctgactatca cgaagatact
    12841 ttagcattac atggttgctt gtctgcagaa ttatctcaag gtgagacatg gtcagtggaa
    12901 aaagaaatta tcgttcttac tagtagagat attccagaag cgcagcaagc agaaaaagct
    12961 gtctcagaat taacgaacca gacaaacaat tatatccaag caaaagaaga gcaaacagcg
    13021 gcttgggcag aacgatggaa gcttgccgat gtggtcatcg aaggagacga agaagcacaa
    13081 caaggtattc gattcaattt gttccaacta ttctctactt actacggcga agatgaacga
    13141 ttgaatatcg gccccaaagg attcacagga gaaaaatacg gcggagccac ttactgggat
    13201 acagaagcgt atgctgtccc tctttatctt gctttagcca aacctgaagt aactaagaat
    13261 ctgctgaaat atcggcataa tcaactgccg caagcaatcc acaacgctca gcaacaagga
    13321 ttaaaaggcg cgctttatcc tatggtcacc ttcactggtg tcgaatgcca taacgagtgg
    13381 gaaatcacat tcgaggagat tcaccgaaat ggcgcgattg cctatgcaat ctacaattat
    13441 acgaattaca ccggcgatac ggaatatttg aaaaatgaag gactggaagt tttagcagaa
    13501 atcgcacgct tctgggcaga ccgtgtccat ttttcaaaac gagcaaataa atacatgatc
    13561 cacggtgtga ccggcccaaa cgaatatgag aacaatatca ataacaattg gtatacaaat
    13621 acgatcgcag cttgggtctt gcgttacacg cgagaaaatt atttaactta tcaaaaagaa
    13681 gctgctatca ctatcagcga agaagaacta gccaaatgga aagatatcgc agagaacatg
    13741 tacttcccag ttgacgaaga attaggaatc tttgtccagc atgacacatt cttagataaa
    13801 gatctcatgc ctgtatccga tattcccaca agcgatcttc ctctgaatca gcattggtct
    13861 tgggacaaaa cccttagatc ttgcttcatc aagcaggcag atgtactaca ggggatttat
    13921 ttcttcaatg atacttttac aaaagaagaa aagcaaaaaa actttgattt ctatgaacca
    13981 atgactgtcc atgagtcttc cctttcgcca agtatccatt cgattttagc agcagaatta
    14041 ggaatggaaa gcaaagctgt agaaatgtac cagcgaacag ctcgcttgga tttggataat
    14101 tacaataacg acacagaaga cggcttgcac atcacttcca tgactggtag ctggttgtcg
    14161 attgtccaag gatttgctca aatgaaaact gcccatgatc agttgagatt cgcaccattt
    14221 ctgccaaaaa cttggaaagc ttattctttc catatcaatt atcgcggacg tttattgttc
    14281 atctcagtca cagatgaaca agttactttc aagttattag aaggttctcc tctagaaatt
    14341 tacgtctatg aacagtctta ttctttagcg gatcgtctag aaataacgct aagaaaggag
    14401 gaagcaaatg tttaaagggg tattgtttga tttagacggt gtcattaccg atactgctga
    14461 attccattat cgtgcttggc gaaagcttgg tcaggaaatc ggcattacga tcgaccacac
    14521 attcaacgaa cagctaaaag gcgtcagccg agaagactca ctctctttgc ttttagctta
    14581 tggcggaaaa gaacactctt ttacaaagga agaatttgca gaattagcga aaagaaaaaa
    14641 cgattattat ttagagatga tccagacgat cgaaccaaaa gatgtcttcc ccggggtcgt
    14701 gcctttactg gattctttaa aagaagaaaa aatcaagatt gctcttgctt ctgcaagtaa
    14761 aaacgggcca ttcctacttg aaaaaatggg tcttacacct tactttgatg ctattgccga
    14821 cccggcagaa gcaacaaacg gaaaacctgc gccagatatc ttcctccttg cagcaaaagc
    14881 tgtcggacta aaagcagaag aatgtatcgg gatcgaagac gcgcaagccg gtatccaagc
    14941 catcctctca agtggcgctc aaccaattgg cgtgggacgt gctgaagacc ttggagagga
    15001 gatcccgctt gtccctgata cgacttttct tacgatcgat tacttgaaag aaaagtggca
    15061 tgaccatgga taatccagag atctccgtcg taccagttcc agagactgaa ataaagaaaa
    15121 tcacattgaa gaacgactac ttagaagtcg ttcttctcaa ttacggtgcc cgcctgcacc
    15181 aaatcttcgc accagacaaa gaaggaaaat cagaaaatgt tttattgtct tacgatcgtt
    15241 tcgaagatgt tctaacagac aaaagctttt ttggagcaac tgtcggacct gtagccggaa
    15301 ggatccggga tgcttcttgg ggtgagcata gattggagaa aaactgcgga tcacaccata
    15361 tccacggtgg cacgaaaggc tggtctttcc aattttggga agtagaagtt ttcaaaactc
    15421 catcatcaat aggtgtggtc ttttacttaa aagatgaatt ttctacctat ccaggaccaa
    15481 tcactgctac gatcacttac cgtttaacaa aaaacgaatt agagatgaca acctctgcta
    15541 gtagccttgt tgaaaccatc tgcaatccga ccaaccatgc ctacttcaac ctttcaggaa
    15601 atggaacaag agacatctat gaacatcagt taacggtctt tttagatggt gtgcttgaat
    15661 tagatcaaga aaaactgcct actggaaatt ggacaaaaaa agaaaaactg ccaatcgact
    15721 ttagaaaatc cccaacactg caagagatcc ttgcatgtta tccagatgga ctagatgatg
    15781 tatttctttt gcatcatcct aggctttcca aaacttcctt acaattattc gagaagcatt
    15841 ctggtcgcca aatgactata gcaacttcta ataaaagtat ggtattattt tctacgactg
    15901 gattcgaagc tgatttctct gtcaatggaa aacagatgca ttcaaactac ggattagcaa
    15961 tcgaaccgca agaaatccct gatatcgttc atttccccaa atttggatcg atcaacctcc
    16021 atcctggtca agaacggatc agtcagacga tttatcggtt ctctgcacaa taacaagaga
    16081 aaggtgtttt tatcatggct attaccgtaa aagatgtggc gaaaaaagcc ggtgttgcca
    16141 cctcgaccgt ctctcgtgtc atcaacgatc atcctagtat ttccgagaca acaaagaaga
    16201 aagtccgaaa aattatggat gaactaggtt atgttcctaa catgactgcc cgcaatctag
    16261 gaaaacgcat ttccagtgcc atcggcgtaa tcttaccccc tcttgattca aaagagcgga
    16321 tcggtaaccc attttatctt gagatcatgg aagcaatcaa cgaagaagcg cggaattatg
    16381 atatgactac agcaatcgct actgctaaaa attttgaatt gctgttagag aacgtccagc
    16441 gtatgcattt acaaaaacaa gtagatggtt ttattctagt gtattcagat agtcaagata
    16501 ctgtcattga ttatttatac caaaaccaca tccctttcac tttgatcgga cagccttatc
    16561 atcatgagaa cgaaatcgtt tatgtagata atgataacca gcttctaggt aaacaagcaa
    16621 cagaattttt gatccagaat ggacataaga atatcctgtt tgtgacaaac acgactcatg
    16681 aaagtttgta tttcgaacga tatttcggtt atcaaaaagc aatgatgatg gctggtcttc
    16741 ctgcgttatc cagtgtagta ctagagcatc cggaggatta tctgtccttt gagaaaacgt
    16801 tgaaagaaaa cgaagccaca gcattggtgg tcattgacga tatcttcgcc cttcgcacga
    16861 tgcagttggc gcaaatgtat ggctatgtca ttccagagac actctccgtc attagcttca
    16921 acaactcgat cttctcaaca ttaacacacc cttaccttac aagtatcgat atcgatatct
    16981 ccgaattagg acgtgtcgct atgcaaaagc tgcgcgaatt gatccatgaa gaattgagca
    17041 gtggcgtacg tttggtcatc cctcatcgct tgatcaaaag agagacagtc gttcctttag
    17101 aaaacccata ctaaatagct gactcactaa atacgctgac catttatcct atggtcagct
    17161 ttttatgtaa aagaagatac tacttctaac acattgttta tctgtaaaaa agagcgtggg
    17221 acaaaagtaa agaacacttt tgtctcacgc tctaaacacg tataaacggc ggaagcagaa
    17281 gcaactcctt cggaaataag ctgaaattca caaaaattta aaaagcaatt ttcttgagtt
    17341 tcttcttatt tcttggagtt aaacgcttct gtcccagcct cttttttcct tccttcaatt
    17401 ttttacacgt cgacgattca ataaaaaacc gcctaatatt gtaaagacag gtgcaagaat
    17461 cgagaaaaag gcgaatggca agtaatgcaa cgcgctaact ttcatcgttc ccataatgaa
    17521 tgtgccgctg actccccacg gtacgagaga attgacggtc gcacctgaat ccgctagtgt
    17581 tcgtgtcaaa taggtttttg ataagccaac gtcatcaaaa gaacgcttga atgtttctcc
    17641 tggaagaatg atggacagat actgttctcc aacgatcaga ttgattccga tacagctcaa
    17701 ggcagtaaac ccgactaaac gagaaggtcg gtccatcttt tcttttaatt cttgaacgat
    17761 ggtatcaacg atcagatatt tgatcagtaa cccacctaat gccaatgcaa gtaaaatcaa
    17821 actagcagaa cctaacatac tcatgatccc gcctcgagaa agcagttcat ctagctttgg
    17881 atcaggtgta tttgcgacat aaccattcat caagatgtct gctgcttttc cgaccgtcaa
    17941 acttttctca tggataaaag aaagaacgag agcagctgtc gatcccgcta gtaatgtagg
    18001 gatagccgga atttttttga ttgccccccc caaataaaat aactagtgga atcaatgtcc
    18061 aaggagagat ccaaaagctc gctttcatgt tttggatcat ttcattgata ctagctagat
    18121 cggctgaatg actgttatgt cctaatatcg tataaaaaat caacgaaagg acgaatgctg
    18181 ggaaatccgt ataacgcata ccagcgatat gttcgaatag attaactcct ccaatacccg
    18241 ctgccaagtt ggtcgtatct gataaaggcg agcagttatt ccctaaaaag gcaccggaaa
    18301 cgactgcgcc tgtagtcatt gcatcattga atccaagtaa atgaccgatc cccaaaaaag
    18361 caattccaat cgtcgaaatc gttgtaaatg aactgccgac agtcactccg acaattgcac
    18421 aaacaagaaa tgctgtcggt aaaaagaaac gcacagaaac aagtttaaat ccataaacca
    18481 taatcgtagg gatggttcca gataaaatcc atgaagcaac taagacacca atcaaaagaa
    18541 aaatcaggat tggaatgatc cctggagtga ttcctttgat gatcccgtca tggatctcat
    18601 cccatgtgaa ctttttaaat ctgccataaa acaacaaaca catgaaagct gcaaggatcg
    18661 ggatatgtgg cgagagctgg aatccgatga tcagtactcc taggagtgcc aacaacacga
    18721 tcaatacagc gatactttct tttaaagaaa tatttttatt catcgtcgat ctcctatttc
    18781 aaatgaaaag gccctgccat gaaaaaacta ttcacttggc aggacctcct actaaatcag
    18841 cgacaaaacg tcggctgaaa gacttatttt tttatttttc ttctaaactt ttttctacct
    18901 caatccccca agaatctttc ttgaagtgat tgatgatcaa tggaataacg aacatgacca
    18961 ctgtgatagc tgctactaat aatgcatcac tcaatgtcgc tgtacctaat gtagcaaata
    19021 cgacaacgat gatagagaag atcagcatgc agctgactac ccaagctaat ccgtttccgt
    19081 ttttaccaat tcggtaagga cgttcgaatt ctggatgttt cttacgcatt ttaagcaatg
    19141 aaacagcaat caaaatgtac acgatacaat aaataacagt tgtagcattt gtaagtgtca
    19201 agaatacagc acttacgtca tccattacac cataaagcaa agcaaataat gaaataacga
    19261 ttgattgtgt tagaacgaca tttctagata cgccgtattt gttttcttta tggaatccga
    19321 attttggtgg aaggaatcct tcacgagcta cttggatgat tgtttttgat ggtccagtaa
    19381 cccaagctga taattgtaaa agcacaccaa taaataccat gaagctgaag atatttccga
    19441 tcacttctgg taagcctagg atttgacagt caatcaagat aggctgcgtg atatttgcta
    19501 attccatttt tccatctggt acgacatttg ctacaagcat cgcattgatg acattcaata
    19561 aaactaatcc gatcaaagcg ataaatacgc cttttgtata attttttgtt gcgtctttca
    19621 aacgaggcat gtaaacagaa ctcatttcga tcccaacaaa aataaatgtg ataccagcta
    19681 agtatttcaa tgaatcaata tgttccaagt cagggaaagc ttttgaccat gaaaagtcac
    19741 ctagatagcc gtttgagact agtccgactt tgaaggctgc caaaacacct aaaacgaaca
    19801 tgatgactac tgggatatat acccctagcc atacaccgat gttcccgccg acttttgcca
    19861 tatcgaattt caagttcaag atcgtgatga tccagtagat aactaaaata caacctaaaa
    19921 cgaaccagtg attattgcca agttctacat taccaaatgt gtttcctaac aatggtccta
    19981 aagtagaagc gaccattacc atacctggga acatttgcac ccataatagc catgcaacga
    20041 caaatcccca tttgctgccc agtgctgttt ttacccataa ctgaggaccg ccttcttgag
    20101 gaagcatcgt ggaaagctca ccggaaacca ttgatatcgg accggcaaaa aacaaaactg
    20161 caaaaattga ataaaaaatc aatgtccaac cgactgcggc taacgtagga atactccgaa
    20221 ccgttgcaca cagtgccatt gtcagaccga taaaggtccc aagacccatt ttacttactt
    20281 cagatttact caccgttgac actctccttg attttttgga taaaataacg gtgtctttga
    20341 agtagtttca gcaataaacg aaacaattca gcgaatattt gaggggattc tttgagttta
    20401 ttgcttgaag ggtttcttca aagacaacct caaaacaaag ggatcgaaga gcttaggtct
    20461 ccccttgctc ttcagatcca aacatgcgtc agaaacagtt agtattcaag ctgttttcta
    20521 acatgattac cttgcttatt ttgcttcgct tgccaataat tggtctgcgt agattttttc
    20581 caatttttct tgaagagctg ctttgatttt ttcagcatat tcttcaaagt gttcttcttt
    20641 gttcatgtat ggtgtcatta cgctggcacg caatacagtt acttttccgg cacggttcca
    20701 ttcttcatct gagaatccta gttggttcac aaattgtaat gggctgttgc catagtctgg
    20761 gatagcaaag tcagtatgtg aagttaagaa ctcattaccg taaatgcttc ctttcacgta
    20821 tgaagaataa tcatatacgt catggttcaa tttattcatt gcaactaagt catcgttgcc
    20881 tttttctttg aatacatagt ctaccatatt gaaatctgga taagttaatg gatgaacttc
    20941 gatttctttg tctcctactt taaatgacaa gtcattcaag aagttgtaga aacgatgtgc
    21001 accttcgatt gatgcaccca ttaatttacc atatcctgtg acattcaaag gtaagacatg
    21061 gtgtgctgcc caaacgctgg ctgctgttgc ccctgctttt gaaccttcca agatataagc
    21121 cccaagtaat gctgggatat ctgcgccttt ttcaaataca tatgtcgcaa agtaagagat
    21181 aacgtctctc atgcggatat ctttgatgac gataccaccg gcagaatatg gaacatagcc
    21241 cattttatgt gggtcaatcg ttacagattc tgcttcttcg attgctttat atgcactgtg
    21301 tacttcttct aagatataat ctttgttttc tgtaaagaca ttgtatttgt aatgaacatc
    21361 ttttaaatct tcaaatggaa tgaagttgtt gtcttcgtct aagaaaatcg cacggccgta
    21421 tccgccataa gcagcatcta cgtgtaagta gaagtaaata ccgtcttttt ctaatacgcg
    21481 acgcaatgca acgattttat cgataccgtc gattgctcct tcttctgttg atcctacaac
    21541 accgactaca cctaggattg gtgttttttc agctgctaga ccacgaacga ttttttcaag
    21601 ttcgttgatg tccatgcgat agttgtggtc aactggcact ggaatcactt ggtctaaacc
    21661 gataccgatg atgtcggcag cttttagcca tgaatagtgt ttagtttgtg gaaccaacca
    21721 ttttcctaat ttttctaaat gttttccgct acgtgctgag tgagctttga tttcgtcgat
    21781 tttttctggg acgctgtcta acagattcat gatttcttct gttgacaagt tcattaattc
    21841 ccaatcgctt tttccagcaa ctagttcagg tgtcacttct ttcattgcaa gcggcaatga
    21901 tttgatgttg cgggcatacc aaagtccttc taagtttgct aaagaaccat cagcaacgat
    21961 gtggccccag ccatctttat agctcattaa ttttgcaaat tccattccta cttcttcttc
    22021 catttggctt gttgcaggag aagattcata ggcaacgtta ttaccattcc atagcatagc
    22081 aaaattgtac gctagtaaag atggcatcaa tgtttcagag ttcatatgac cccagtaacg
    22141 tccggcatta tgccaaggaa cggaatgggt acgcatccgc gctgaaattt ctgatagaac
    22201 atcctttgtt ttattcacag tgtgttcaaa actagcactg cttttttctt ctggcgtaat
    22261 aataggcatg tcttgaggca tgtagttttg acgccagcct aaatgttcat ccaccaattc
    22321 attcaacaaa gctttataga tttggccgtt ctcagctttg tccccaatga atagggcatt
    22381 taggtttaga tctttcgaca atgattcact catagtgaaa ccctcctaaa aaaatattta
    22441 aattttgtcg agccctacat tacacctgtt cttctattct gtaaactaag ttttggcctg
    22501 atttttaatc atattttaat atgtatcaat tatccgaatt gttcacactt ttgaaataat
    22561 taaaaaaaac gagggaattt acaaatgtaa actccctcgc aaagattgta ttaacgacaa
    22621 ccagcgttct attttaggat gggtttcaaa attggaatgt tgtaatagta tttccctttt
    22681 tcaaggtaaa aacttactaa attctaatca attactttgg ccaaaaagta atttttctta
    22741 ccttttcgaa taaccacaaa cttaccatcg aattcatcgg atggatttat gacaaaattt
    22801 aaatcggtaa cgcggtcacc gttaatactt atagctccgt ttgaaacatc ttcacgtgct
    22861 tgacgtttag atggttcaat ttttgtggaa acaagcagtt ccacgatatt ttcaggtgtg
    22921 cttgaaattt caacgttcgg cattttaccg aatccttgcg cgatttcttc cgcatttagt
    22981 tctttaatat ttccagagaa caatgcttgc gttatttttt gcgcttcttt caagtcttct
    23041 tcactatgca caaatcttgt aacttcttct gccaaacggc gttgtgcttc acgtttctca
    23101 ggttctgtct ctactttttt cgctaagtct tcgatttctt cttgagacaa gaaagtaaag
    23161 aatttcaagt atttcactac atcgcgatca tcttgattca accagaattg gtagaactca
    23221 aatggtgaag ttttcttcgg atcaagccaa acggcaccgc ctgcagtttt tccgaatttc
    23281 gttccgtcag ccttcagcat caatgggatc gttaaaccga acgcttctgc ttctggtcct
    23341 tctaattttc ggattaggtc taatccagct gtgatatttc cccattggtc tgctccaccg
    23401 atttgcaatt gcacatcgta tgttttatgc agatgcaaaa agtcgataga ttgcaggatt
    23461 tggtaagtaa actctgtaaa tgagattcct acttccaaac ggctggcaac gatatctttt
    23521 gctaacatcg tgttgatgtt gaagttttta ccgtagtctc tcaaaaattc aagtaaagag
    23581 atttttgaca accagtcgta gttgttcaca aatgtgatat ttgcatcttt accaaacaat
    23641 tttctcattt gattggaaag tgcgtccacg ttatgttgca cttgttccat cgtttgcaac
    23701 acacgttctg ttttgcggcc gcttgggtcg ccgatcgttc ctgttccgcc gccaatcaga
    23761 atatatggat gatggcctgc caattggaat cttttcatca tcataaatgg aatcaaatgt
    23821 ccgatatgca tcgaatcacc agttggatca acgccgcaat aaagtgaaat gctcttttct
    23881 tcaacgagct cgcgaagtct ttcttcgttt gtttgctgat taatggcgtc gcgccaagtt
    23941 aattcatcaa taatattcat tttactgacc tccgtgtagt ttttttatga aagcaggaac
    24001 ctgctagcat gtgtaattaa ttatttcttc aggataggat aggaaataaa aaaagtccct
    24061 tggcatataa gccaagggac gaaatctcgc ggtaccaccc aatttgtatg tctagatatc
    24121 caacatacct ctcgaacatt taacgctgtc gcgtggcaat cactgccaaa gactcctgaa
    24181 atgtaattcg ctttaaagca tgtactggtt tgcagcgacc accagctttc tgaaacattg
    24241 gctttaacaa ctacttcgtt tcgatcttcg tcttgttatt attaatatgt gtctatcata
    24301 gagcgcaact ttttctttgt caacagaaaa aggatatttt ttttaaattc ctcatttttt
    24361 cttttttgaa tccgctctaa ttccgaacat tttattttca attattgtta aaagaaataa
    24421 ctttttctgt attttttctg caatttatcg agaagtcact ttactttgcc tcttattctt
    24481 tcttcgttac aataaggaat gggacaagta aaaaaatgaa aaagcaaggg acgaggtata
    24541 tggaaaaaaa gcaaaaaatt attttaggag ccacttctgc tttaactatc gttattttaa
    24601 ttctaagttt gttttttgtc atccgatcat ctacaaaaaa agaaccaatc attcctgaaa
    24661 aaaaaataac agaaaaagca aaagaaccga cagatgataa gcaacaacta gttactcaag
    24721 caaaaaatct ggctcaaagc tacgattatg accaagcgat tgcgttattg gaaaaagata
    24781 gtaagaacgg atctactgaa acacaacagc ttcttcaaac actaaaaaag gagaaagaac
    24841 aactgatcga ctggtctgat cctactcaga tctctcatgt ctttttccac agcttgatcg
    24901 tggacccgca aaaagccttc cactctcaac aggcacaagg atacaaagat tatatggtga
    24961 ctgttgaaga attcaaccgt tcgatcgaac aactttatca aaatgatttt gttttagtta
    25021 atttgaatga tttgatccaa aaagacgaac aaggaaatct ttcctttaac gggcttgcgc
    25081 tacctgaagg aaaaaaacca ttggttcttt cacaagatga tgtcagctat tatgaatata
    25141 tggataattc cggttttcct agccgattgg tcgtatcaaa taacaatgaa atcaaaaatg
    25201 tctataaaga gaaagataaa gaagaaatcg gtgactttga catggttcct ctgatcgatg
    25261 cctttgtcaa gaaacatcct gatttttctt atcgaggcgc aaaaggtacc ttggccctga
    25321 caggttacaa cggagtttta ggttatcgaa catcaaaatc tcaatatgga gacaatgaaa
    25381 aaacaaaaaa agagattaaa gaagctaaaa aagtggcgga acagttgaag aaagacggct
    25441 ggagctttgc ttcccataca tggggtcact tgaatatgac tcaagcttca ctagaagatg
    25501 taaaaaaaga caatgaattg tggcagcaag aagttgcacc tatcctagga aaaacaaata
    25561 ttctgattta tccatttggt gcagacatca gcgactggca gccttattca gcagaaaatc
    25621 aaaaatttgc ttacttgaag agtcaaggtt tcgatatttt ctgtaatgtc gatgcttcta
    25681 caccagcttg gggacaatta ggtacggatt tctatcgaaa tgctcggatc aatatcgatg
    25741 gcattcgttt tcaatctgat ttagacggaa aaaatcctat tcttgatcca ttcatcaatg
    25801 tccatgatgt ctatgacaaa gaagcacgcg aatctgcttg attttacgtc atttatgaac
    25861 caaaaaagcc gaactgacat tttatcgtca gtttcggctt ttttatgctt tatttcttct
    25921 tcggtgcgat tcccttgatc aggacttctg tccattctgc tgtatatgga agcagttttg
    25981 cgtatatctc cggcttagaa attccttcta ccattgcttg aaaatagagg atcaagaact
    26041 catccgaata tttcaaatcc acttttcctt ctttccgccc tcgatggaaa agatcaagca
    26101 tgatactgaa actttcttgc gtatacgcat ccatcgcgtc agaaaattct tttttttctt
    26161 tttttgtata gtatgtcatc aaatcgatat aaaattgttt gttcactcga ttgagataac
    26221 ggattttgtt ttcactcatg gcaatcagtg tttcttcaaa tggaagattt tccgcaatca
    26281 acgctttcgc ttcttgccct aaatcattca taaatgcaaa aaatacttca taaatcagcc
    26341 cttccttgct gccaaaatat ttaaaaatcg tcgctttact tacctgagcg ttctcagcta
    26401 ccttatccat tgtcactcca gcggttccta tgtctgtgtt catcaagtca aaagctgctt
    26461 gtaaaatctc tttctttttc tcttgtgctc tcttttcaaa accgttcatt tgtagagcct
    26521 cccgtaattt taaactttta taatatatat agttcaaatt tattctgagg tttattataa
    26581 ctatctattg agaaagtatc aagctagcaa ttccttgttt atgaattcat tgacagaaat
    26641 ttataaaaag aatattatgt actaaaataa taaaaaaagt tttataaaaa ggtataaaac
    26701 ctttttatta aactatttaa tcttgtttag tatatatttt tagaaaaagg agtggggttt
    26761 ttatggcaga aatcgtcaaa gtcacacatt tgaaaaagag ctttggtcgt ttcgaagctt
    26821 taaaagatgt ctctttcacc gtacattcag gtgaagtcgt tggatttatc ggaccaaatg
    26881 gttctggaaa atccacgacg attcggacac ttttagggat tataaaaaaa gacggcggaa
    26941 cggcaacgat ttttgggcaa gatgtatggg aagatagttt atctatccat gaacgtcttt
    27001 cttatgttcc aggcgatatc tctttgtggg gaaatttgac tggaggagcg atcatcgatc
    27061 tcttcatgaa gcttcatgga aaagggagtg ctcaaaaaaa agatgaactg attcaacgtt
    27121 tctctcttga tcctaagaaa aaagcaaaaa actattcaaa aggaaatcgc caaaaagtgg
    27181 gcttgattgc tgctttggct gttgattcgg atctctattt atttgatgag cctacttctg
    27241 gtttagatcc tttgatggaa acgattttcc aagaagaagt tgaaaaattg aaagaacagg
    27301 gcaaatccat cctactttct tctcatattc tcagtgaagt cgagcgacta gcggataaag
    27361 ttgtgatcat acgcgaagga acactcgatg aagaaggaac actcgatgaa ttgcgtcatt
    27421 tgactcgttc gaccatcact atagaaacag aagcagagaa tagtcactta gcacaattga
    27481 acggtgtcca tgactttgtg caaaaaggtc acctcgctca atttgctgct gataacgaag
    27541 ctttcgatgt gattttagct gaagcgtcca aattaggtgt gaaaaaattt gaatctattc
    27601 caccgactct tgaggattta ttcatgagac attatgaagg atgaggagga agcgaaatga
    27661 ctgataaatt ttcacgctgg tccacccttt tttctcaaaa ccttagccgt gactggaaaa
    27721 agatcctgat atggctagtc ggtgtcactg ctttttctgg tggttttgtc cctgcgtttg
    27781 aagaattgac ttccggacaa ggattagctg gattatacga aaccttgcaa aacccggcaa
    27841 tgattgcaat ggtcggacca actccagctt cgaatgctgc tgagtatact ttaggagcga
    27901 tgtatgcaaa tgaaatgttg cttttttgca gtttgtttgc tgctgtgatc tctgttttac
    27961 acgtggtgag ccaaacgaga aaaaaagaag aacttggtct gattgaactt attcgttcct
    28021 ttcgagtcgg acgtcaagca aactctttag ctgtcatcgc tgaaagtatt ctgatcaatt
    28081 tgcttttagc aatatcgatc agttgtacga tgattttttt ccaagcggat tcgatcactg
    28141 cagaaggtgc ttggcttttt gggctatctg taggtagtat ggggattttg gggagtgccg
    28201 ttgcactgtt tgctgcacaa ctgatgccaa gttcagccag ttcgaatggt ctgtctttag
    28261 cgtttttagg tggactttac cttctacgag caataacaga tgtagctgat tcctcccttt
    28321 cgatgtggaa tcctttaggc tggtcttatt tgacctatcc atttacaact aacaactgga
    28381 ttcctttgct ttatttgttt ttgttcagtc taatcttgat aatcagttca tttgttttag
    28441 aggaacatcg agatttgaac accggctata tccccgaacg tgaaggaaaa ccgtatgcta
    28501 aacgttctct tttatccttg cgtggtttat tattctatct aaataaaggg atgacaatca
    28561 gttggcttat cacttttggt ttgatggggg cggcatacgg ctctatctac gggaatatgc
    28621 aacagttttt agaaagtaac gacttaatga aacagatgtt tatccaatct ggcgtctcaa
    28681 ttgaaaaaaa ctttacaagc acgatcatgg tcgtcttgat ttgtctagct gctattttac
    28741 caattgctag catcaatcgt ttatttacag aagaaaccca cggacgtatg aatcagctgt
    28801 tcgcaacaaa aatttctagg aaccaacttt attggaccaa tatgttacta gctattctat
    28861 ttgctatatt ggcaatcctg attagttctg gtgcactagg gctttctgct ttggcttcga
    28921 tgaaggatgc gaaagacatg gatctattga tgtttcttaa agccgggttc aatttcctgc
    28981 ctgccgtttt agtgtttatc ggaattagtg gctttctatt cggatggctt cctcgaatcg
    29041 gtaaacttgc ttatatctac ttagcttact cctttgcact caattacttt ggcggaattt
    29101 tggatttacc agaatggttt tccaaaacag ctgtccctag ctgggttcca cggatgccaa
    29161 acgattcttt tgatctttcc gtgttcctta cgttatcatg tatcagcctt gcactgttcg
    29221 tccttggttc tattggttat aggcgaagag acttactaga aggataataa aaaagcatgt
    29281 acaatttcat gctagcctcc aaatctgggt caaaaatcca acatttggag gtcatttttt
    29341 tatttacaag tcttctaact gctctttatc aatgatccag acttctcgat tctttctttt
    29401 tacataacca ttctcctcta ataatttaaa ttttctagat aaagtttcgg gggtcgtacc
    29461 gataaatgca gcaagttctt tcattttcat tggcaggaaa aagtgatcct tccctgtcgc
    29521 tttagctaag tcaagcagat agacagcgac tcgttcttct actttttcca tcatcaaaaa
    29581 agttgtctgc tgctgtactt ttgttaattt ctcaacgttg attgctaaaa gtttcagact
    29641 aagggcggga taatgcagta agagttccga gaaatctttt tgtctcaata tgcaaatttc
    29701 cgttttttct agtgcttcgc caaataaaga ctcatttgga acgcctagca actggctctc
    29761 tccctcatat ccgcccggct ctattactcg taaaagctgt tcctttccgc tagcagataa
    29821 ttgatacact ttcatactgc cggaggccac gatcactaat tgaggttctc cattcggcgc
    29881 aagaatctgt tctccttttt ccacatagtg atgtttgaca agtgcgtgta ctttttcttg
    29941 atcttgctgt actaagtgat tgaacaaagg aacaaatgaa acacataaat gatcatgact
    30001 cataatctct cctccttcta aacagctatt tctaataaag aaacataact tcccttattc
    30061 caactgataa ttttctttta tcatagcata aacgtcaagc gaaccagata ccagcaaata
    30121 gagtggattt ctttttgtcc cttgctttat tttccttctt ttgagacctt aagtaattga
    30181 ttcctatcaa ttttttaaat atttactttt tgaataatca aaaacaaacc ttcactcgca
    30241 agccgagagt aaggtttgtt tttcgcattg cttatttcgt gttgtctatt gaaatttttc
    30301 cgcacctagc ttttgatata gtggtgctag ttcttgtaag gtttcagcgg ttatttgctc
    30361 aacgtgttcg atttcttgcg gatagaagaa tagtttaccc atttgaaagg ttcggtctct
    30421 catcgctttt ttcaactctt cttgtttctt tgtatcggac aaatagtcag acaaagctaa
    30481 gtggtcgtca agttcatgtt ctggttgcgg ccatatgtaa taatccttga tatcgactgt
    30541 tttgctccac tctttcagta tcgcaagcaa ctggttatac gctgcaatgc taccatatcg
    30601 ttcttcgctt ttataatgtt ggtacatcaa atagatttgg tattgttttt gattcaacaa
    30661 aactgctaga caggcattct cgtcttgacg agattcgctt cggtacgcgc tccaaaaatg
    30721 actgcgtaaa ttccagccat tcgtccagct ttcgatttta ggtttgctca tgccgtacat
    30781 atcaggcaaa agtgcagctg tctggagctg aatctctttc catttttgcc agtgttcttt
    30841 atattctttc ttgatttgtt caatcttatc tgttggatgg ctctctttga gctgtttgaa
    30901 tgcgtagatt ggtcgatcaa acaactgata atctgatttt ccaagttcca ttgtttcgcc
    30961 tctttccgtt atcttttgta ttctacctga attttgcgat atggacaaat agaggttgtg
    31021 aaaaagctgt tctgcatcaa gtcataagaa cagccaaaca aaaaactgcg atgagcatca
    31081 ccgcagtttt attgaactta aggttgattg atcacatcta aaagcgttga aaataaaatg
    31141 gcactagaag cagctcctgg gtcgatatgt ccgattgcac gctctcctag ataggaagct
    31201 cgtccttttt tagctaccaa gactttggtg tgttcttttg cctggtcaat gatttctttt
    31261 gttaaattcc ctgccttcaa tgcctctgtg actggcagcc aaacatctaa catcgtttta
    31321 tcgtcagctt ctgcctttcc tcggctttga atacccgctg ttccctgctc gatcacttcg
    31381 cctaattttt cttgagaatc aatagaatcg acctcttttg tcgctttcat catgttcatg
    31441 aatgcagatc cgtataacgg accagaagcc ccaccgactt tcgatatcat cgccatagag
    31501 aatactttga atgtatcgct gattgtttca ggatgatcgg cttgaaaagc ttcttcataa
    31561 gctgaaaccc ctcttcccat gttatttcca tggtctccat cgccaatcgg ggtatctaga
    31621 tcactgagat attgtttgtt ctgattgatt gcctctgcaa attgcgtgag ccattcttgg
    31681 atttcttgaa cggttagttt catattatca cccttttatc ttgagatttt ttaccatgaa
    31741 atcgtctgta cattgctttc taaagaatct ttccattgtg tctccgtcaa gtcgatcagt
    31801 gttagagaaa gaccttgcat atctagtgag gtcataaaat taccgacttt tcggaaaact
    31861 acattgacgc ctctttcttc caacagagct aaaacatcat tcatgaacac gaactgttcc
    31921 atcaaaggcg tcccgcccat tccgttgact agtacacctg cttcttttgg taaattcgag
    31981 taatcatcta aaatcttagt aacaagttcc tttgccagta ctttagaagg ctgcatcttt
    32041 tctcgacgat agcctggctc accgtggata ccaacaccat actcgatctc atcttctcct
    32101 agttcgaatc ctggtttccc tacttctggt acagttgctg ctcgaagcgc tagaccgatc
    32161 gtcttagttg cctgtacgac cttttctccc agttctttca actcagctag ggaagcaccg
    32221 tttcttgctg catcgcccac gattttgtgt acaaggacag tacctgcaac tccgcgtttt
    32281 ccagcagtat acgtactatt ttcaacggcg atatcatcat ctacgatcac actttctact
    32341 tcaatatcgt ccatagcagc taattccttt gccatatcga agttcaatgc atcccctgta
    32401 taattcttaa cgatcagcaa aactcctttt ccactatcgg cttccttaat agccgtctga
    32461 atctgatctg gagttggaga agtaaacaca tcaccaagca ccgctgcact taacatccct
    32521 tcccctacaa acccggcatg ggatggttca tgtccgcttc ctccaccaga aaccaaacca
    32581 acttgttccg ctttctgatt cttggctaca acacgggaag attctacacg atgaacaagt
    32641 tctggatagc tttttactaa tccttccagc atttcttcga caatattgct tggatcattc
    32701 atgatttttt tcaatttatt cccatccttt ctttccggca ttttgtgctt ctgttaagat
    32761 ttgctgagta tcatctgtta taccggcagt gatggctgct gcaaaagctc cttccactaa
    32821 aggcgcatcc accagatgat aacgttgctg ctgctcttct tccaacatgt cttttgccag
    32881 ttccgagttc aataccgcgc taccgatatc cgcaaaaaca aaataactag ctgcatcgct
    32941 tgattcattg actgcttcta cgattttcat cgggtctgat ccgatctcgc catttattcc
    33001 gccgagagaa aaaatttgca cctcttcgga tttttgcatc tgctcaatca tttctttaat
    33061 accatctgtt actttttgac tatgagaaat aagcaaaata ctttttttca caagaatctt
    33121 cctttctttt acatagttgc taacgattgg tttcgctttc attaatgaac aattcaagta
    33181 tataataaat ttctaatttt gggaaaatat gtgtagtgct tcttgaagtt tgttatactt
    33241 taattaaaag agaggagtga tcgaatgatt acaacaacaa cgaacagtgt agagggaaaa
    33301 gccgtagtag cttataaagg gatcgttttt ggtgaggtca ttactgggat ccatgcattt
    33361 aaagacttgg aggcggggtt gcgaaatatc tttggcggcc gctcaaaaag ctatgaaaac
    33421 gaactaatgg gtgcaagaga agaagcactt gccgaaatgg ccgaacgtgc aaaagcatta
    33481 ggagctgatg cgatcattgg cgtaaaaatg gactatgaag tattaggcag cgacaatggc
    33541 atgctgatgg tcacatgtag tggaacagct gtctccacga gataagtagg ggacatctgt
    33601 tttaataact aaagagagat gggacatgta gtggcactca agaattagat ttttcagtct
    33661 aacttcgagg tactctacct tcccatcctc tcttttttat ttctttttgc ggatgattcc
    33721 gtaagctgct gcgactaaca cacccgcccc tgctaaggaa taactgacag aagctgtttt
    33781 ttcatttgtt tttggcaaag tctgacttgt tgatttggat ggctctgtcg tttgctgaac
    33841 tgtttctgtc gtgcttccag aggtcactga tttttctcct gccgaatgca aaatatcttt
    33901 tattcgttgg aaactagctg ctaagtcagc tttttttgct tcaaaatcat tagcaactgt
    33961 ttgtgcttcg ctgatctttc cgtggattgc ttgactggcc gctgtgatat ccgcttgagt
    34021 ttgacttagc tttccagaag ctgtttgagc aacctgattt aattgctgat tgaattcttt
    34081 tgcttgttgg atcttcccgt caagatctgt ttggacagct tccgcttttg ctttcgcttc
    34141 ggcaagcttt ttctcaagtt gtgcacggtc atttcccact ttatttttaa gatcagctaa
    34201 atcttgatcg attgctgctt ggtcttcttt caatttgttt tttgcagctt ctaatgcttc
    34261 ttcgagttct tttcttttat tttccaagtc ttgcaaatga tcgatttggt cagaagaggt
    34321 agaactattt attgatgtat cttctgaaga tgaaatcgtt tctcctgaat tatctgtcgg
    34381 tacattggaa gtcatttctg tttccgaggc accgttttca gcaccagaag agcttatggt
    34441 tgttgaaggt tctgtttgag caggttcaga agtttccgca aaagctgtct gtcccaataa
    34501 gaaaatactg gaaacagcaa ttggccagat taacggcttc attctttttt tcatcacttt
    34561 tcccatcctt actacttttt aactaatttc ttattataag caaaaatgtt tggaagaacc
    34621 ataaacacaa caggctgttt gtctaaaaaa cggtgcatct tttatttttt tgtacgttcc
    34681 gggcttttcc atgtcccgct tccataacct aaaatcgttt tgactgctgg aatgaaagtc
    34741 gtcacgatcg ttatcgcgtt cactatccag aacaaaagca tatatagtgg tgcgaaaaga
    34801 aggtatttca attttcttcg tcgatcatct acaatcagcg aagctagcaa ctggaaaaat
    34861 cctgcgacca tttcaaagca gatgaacaca aaactgaatg taaaagtaat ataaatctgt
    34921 tcgtagtttc cttgatatac ataatgcccg attaatccag caaaaagaac tacggaaata
    34981 caaaagaata ttgaccagac aatactcaat gtttgatcaa tgaagatgat cgttcttcca
    35041 atatgtttaa aaggatggag catcactttt ttgaaattcg tcagccagac ttctgttcca
    35101 ccttttgccc aacgttttct gtgtcgatat agcatcttca acgtcacagg tacttccatg
    35161 aaaaagataa tctcaggagc aaaaacagat aaccagtcat ttaactgatg atcccaagca
    35221 atactgatgt cttctgtcgc tcgatcttgt ctgaatccgc ccacatcgat caaggcttct
    35281 tttcgataca tcgtatttgc tccactgtac gcataaagac caccgaaaac agctgactgt
    35341 gttcgtttaa tgatgcccac gatacttgag aattcaaccg tttgagattt tgcaatcaat
    35401 ttggtacgat tttggacatc catatttgca gtgaccgcag caatatgtct tgcaccaggg
    35461 cgaatgaaat aattcacata cctaatcagt gcatctggct ccggtaccgt gtctgcatca
    35521 ttgcttaaaa tcaatttccc ttttgcaaag gcaagtccga tattaaacgc gtgggctttt
    35581 cctttatttt tttcgatccg aaccacacga agattagcgt attttttcat cagtctagct
    35641 aatatttctg gtgtttggtc cgttgaacca tcgtctgtca ctaatacctc atagttgtga
    35701 taattcaatt tcgtcatcaa atactcgatt gtatattcga tcacaatttc ttcattatgg
    35761 gctggcacca tgatcgtgat gaacggttcg acactcaagg gaacatctac ccattctttt
    35821 tgcttatgtt tgtataaaaa cacataacac cagacaccaa taaaccatac aaatccgcct
    35881 aaaatcggat aagaaacgag aaaaaaatac ataatagaca aacaagtatc taagaataaa
    35941 ttacctgtat gggtgattga gatcatttca gttccacccc attttcttta tacaaatctg
    36001 caatgaatgt cgtatctaga tttttctctt cggagacaga ataaaaacgg accgtttctc
    36061 tctcttcttt tgttccaaaa cgttccgtat acacttcttc aagtaattct tgtctttttt
    36121 tcaatttttc atcttcatat tcaaaagatt tatttacttt tttgtataga tttcgattgt
    36181 tccacctagt caatacaaat gaggtaatca ggaaactgaa aaaaatcaat acaaaaaagc
    36241 cgattaagaa atacagcatt ttcttttctg ataaaaaagc gtacaaggaa aaatccttgg
    36301 ctctttctgg tctcgttaat gggaaaaaga cccatataaa aggaagaaca acgatcatcc
    36361 atcctaaaag agccactaac gtttgccaaa tctttaacca gtaattacct tttgaaaaat
    36421 acttatcttt caccaaaatt gatgcaactt cttctcttgt tacttttttc atatcctcac
    36481 ctcacgtttt tttgttacga cgtaggagtt taccatacat ttcatttctt ttcacataaa
    36541 gtgttcctaa atttttccta agaaaaagaa caaaacattt ctcatcagca aatgaaaaat
    36601 attttgttct ttttatcagt tgttcttttt attttttatc tcttaattat gttgctcttt
    36661 ccaatacgac aatgcttttc attcctctag atatcgccgt gtacatttgt ctgcgtcttc
    36721 tttgctcatc tccatcgttt tcaaatggat ataagattac atgatcaaat tccagtcctt
    36781 ttgctagact caaaggaatg atttggcagt tttctaatcc atatgaattt tttttaatcg
    36841 attcttgtag cgtttgggtt tcctcttctg tttgggtgat aactgccgct ttttctcctt
    36901 ttagagaaac caaaatctca gctagtattt tcaacaattc ttcagaggat cgaaaagagc
    36961 ggtattcggg ttcttttcct tgcggtcgga tcgatacgat gtcgatcttc tcttgatcca
    37021 cagcataggt tttgaaaagc tctgtgattg ctccgctaga acggtaacta tttctaagat
    37081 cataccgatg gatcggcaga tggtagtcgt cgaaacaacg cataatatca gcaaaagtag
    37141 tggaagaatt aaagattgcc tgattctcgt cacctactaa agtaaagtga gtttttggaa
    37201 ataattcgat caatagacct aattgtgcca gggtataatc ttgtacttca tcaatcaata
    37261 gatagcgaaa tgctggtaca tttacctttt caacaagtaa atgacgaata gctaatataa
    37321 tgactgcttc atcaacagta cgtgtgggtt gccaagcata agctgagcca tatcgttttt
    37381 cataaattct ttcaaacaac tgatgctcat ccacccatgc catttcttcg atttgtctgg
    37441 ttatttttcg atattttttt tgtaaaagtt tccttgcata agctacaata ctttgttccg
    37501 aatcatcaga aatcaattta ccgaataatt ccaactgcct atcttctgtc aacgagagta
    37561 cctgattctg cacagcagga ctttttgctt gtttcaaaag atgattcttc cattcgctca
    37621 tcagtgcctt tttcgttgct tgaagcctat cgatcaattt aggatgagca ggaactttct
    37681 catatatttt ttcgatcgtt tttttagaaa ggactgtttt tccattttta gtaagtccac
    37741 ggataaaatt cggatgatct aaaaacaaag gatctgattg ttttagatta tcgataaact
    37801 ttttgctacg caaacgttct gtctgctccg atacattttc tcccgtgata cgtttgaaat
    37861 aagcctcttc accttctatt tcctctgctg aaagctgtga aaccagctgt atgatggtta
    37921 gattcagtgg atttctttca cctaatgatg gtaggacatt cgaaatatag tcgataaacc
    37981 gatgattagg tgatagaatc agcaagtcat cggatgtcat cgtatctcga tataaataga
    38041 gcagatacgc aatacgctgc atgatagcag aggttttacc acttcctgct acgccattta
    38101 ccaagatatt ttgacttttc acatcccgaa tgattgtgtt ttgttccgat tggatcgtag
    38161 cagtgatagc cttcatttca ttggtctcat cttggcctaa gacttctaat aatacgtcat
    38221 cttgaatagc tacagacgta tcaaaaaact tgaccaaacg atctctttcc aaaagaaatt
    38281 gtcgtctttc tttaataacc gtatcgattt tattttgacg aaccgtataa gaagatggac
    38341 caatcatgtt attgtaaaaa agttcggcaa ttggtgaacg ccaatcataa acaagatttt
    38401 catctgcatc atctgtgaaa tttgctgtac cgatataaaa ggattctttt ggctcattat
    38461 ccagaaagtc tacaacgact tttccaaagt agggactttt caataaacgt tcgatctttg
    38521 ctagctgatt ttctgcgttt ttctgtttga tattcatctg atcgatttct ctatttttca
    38581 tttcaatcat cgaaaaagta tccaggttat ctaagtaact gtcaaaattc aatcgaagct
    38641 cgccagccat ttctttcaac gactggtttc cttctatttt tgccgtatcc atcgattccc
    38701 gcagttcgtt ttttttatca attagctttt gatacacgtt cttcagatat gcttcttcta
    38761 actgtttttg tgtgttgacc atacacattc tcctcttttt ttaaagtggt ggaaccgatt
    38821 agtttacctc ttttaagagt cgaatgcaag ctttttaacg agtatcattt gttaggatat
    38881 atcagttctt caggtcggac agtttgatat aaagaaaatg caccatcaag gttttttacg
    38941 tggtagccag actgcttcaa gattctttcc gctagatagc tacgtaatcc gctatgacag
    39001 ctgacgatat attcttgttg gctgtctaat tcatttaatc ggtcccgaag ttcattcaaa
    39061 gggatatgtt tggcttcctt gaatttgccc ttttccaatt cttctgctgt tcgcacatct
    39121 aataaaattt ttccttttgc tagttctgtc ggcaattcat gccattgtac ggtttcacta
    39181 agcccttctg caatgttcat tgctgcatat cctagcatgt ttactggatc tttggctgag
    39241 ccaaatggcg gtgcatacgt caattctaat tccggtaaat cgaagatcgt caaatgccct
    39301 ttgattgctg ttgctaaaat atcgatccgt ttatccacac cttttgcccc aacaccttgt
    39361 gcaccataaa tctcgccagt ctctggatgg aagatcaact tcagtaaaat atctgttgct
    39421 tctggataat agcttgcatg atcttttcct gatacatgaa tgacttcaaa agacagttcg
    39481 ttttctttgg ctgttctttc acttaaaccg gtggatgcgg cagtcattcc aaacgttcgt
    39541 ataattgctg ttccaatacc gccttgattt cttcgagaaa ttccggaaat cgtgtccgca
    39601 acttgtctac cttgacgatt ggctggtgaa gcaagagaaa taagtgcatc ttttccagtg
    39661 atttgctgtt ttacaacgat agcatccccc accgcataaa tatcaggaat attcgtttga
    39721 taacgttcgt ctactaggat acccccgcgt atgcctaatt cgattccagc ggtcactgct
    39781 agctggttat caggacgaac accaatggat aaaataacta aatcagcagg gatggtacgc
    39841 ccatcatcca gtcgcaatcg tttcccgtgg tcttcaaatc cagcgacagc atgagaagta
    39901 atcacttcta ctccttgatg agacaattct ttttctataa aagctgccat ttcttcatcc
    39961 agtgttggaa gaatatgtgg tgcttgttcg atcaccatga cttctaaacc tcttcttttt
    40021 aggttttctg ccatttccaa tccgatgaat cctgcaccaa cgatcacggc acgctttggc
    40081 tgtttttcta atgcatgcat cactttatcg atatctggta catttctaat agaaaaaaca
    40141 ttgtcggctt ctgttatccc tggaatcgat ggaacaactg gttttgcacc aggagataaa
    40201 accaatgcat cgtactgttc aatgtgtttt tgaccctcat gtacgacttc taccgttttg
    40261 ttttcgggaa agatggctgt cacttcatga tttggacgca catctaaaca aaaacgagcg
    40321 gataatgatt ctggcgtttg gacaagaaga ttttcccgtt cactgatttc tcccgaaaga
    40381 taataaggca agccgcaatt tgcaaaagaa acatacggtc ctttttcaaa aacaacgatt
    40441 tctgcatctt ccattaatcg gcgaagccgt gtagcagcag acattccacc tgctacacct
    40501 ccgacaataa cgattttcat cttatttccc tcctactgtt cgatcaaacc attgattcat
    40561 gccaccacgt acattcacta catcataacc agatttcttt aattctttag ctgcttgttt
    40621 actcctcatc cctgattgac aaatcacata gacggtcttt tctttgtctc catcatatct
    40681 gtttatactt tgtaatggaa catttttagc tccttttata tgcccgcccc ggtattctgc
    40741 aggtgttcta acatcaagta acgctggatt ttccaaaagc ttttccttta attctgggac
    40801 tgttatcgat tttattgatt gaaatagcaa attcattttc tgcacctcat ttacattttt
    40861 ataaatacct catggggtat attaaacagg agctttatta atatgtcaac cagaatgact
    40921 cttcattttt ttcactactt tttatatttg cataaaatac cgataagggg tattatctaa
    40981 ttataaaaat agaggagaat gtgttatgga gattgataat aaaaatatcc tgaaccgttt
    41041 gaaacgtaca gagggacaaa ttcgtggtat ccaaaaaatg atcgaagacg aaaaagaatg
    41101 tatggatgtc atcactcaat taagcgctgt tcgttctagt attgatcgcg taatgggcat
    41161 gatcgttgca gataatctga aaaattgctt tgagaaacct gatagtaatc cagaagaaca
    41221 agcggctaaa ctagaacaag cgatcaagat gattattaaa aagtaaagga atgatttcaa
    41281 tgaaagtcgt tttccatatt gatgaattag aaaaatggtc agaaacaggg aaaaacgtaa
    41341 aaaacctgat aaaagcttct ccagaaacga cgattgtcgt atctgtaaat ggcatcgcga
    41401 ttaccggtta tctagactct gccaatgcag aattcttaga tttgcaagga gtcgtttttc
    41461 acgcttgcgc caatgctatg cgtgctaatc atatttcaga aagttcttta cctgaacaag
    41521 taatcgttgt accagcaggt gtccttgatt tagttgaact gcaatcccaa ggttatgctt
    41581 atatcaagcc ttagtcagta gaggttgcga cagaagtgat cagcttcaag aaatttcggc
    41641 ttatttttcg aagaagctac ttctggaaaa ccgtgaatca aaggttgtga aaacgctgtc
    41701 ctgcatcaag taataagaac agccaaacaa aaatagcttc tcatattttt cgtttggttg
    41761 ggcttattac cgcagatgca agcttttgaa caccgtttaa ggaagaggtt gtgaaatcag
    41821 cggtttgacc taagtattag agaaaaaaac gggaaaatag ctcctcatat tttgccgttt
    41881 tttgagctaa taccgaaggt cagctgattg aacaccgttt aaggaagaga ttgtgaaaaa
    41941 gtcgcttagt ttcgagtatt aagaaaaatt ttgtgaaaat ggatttctac atttttgcat
    42001 aaatttggct taataccgag aaactggctt ttgaataccg tttaaggaag aggttgtaaa
    42061 atcagcggtt tgacctgagt attagagaaa caaacggaaa aatagctgct catattttgc
    42121 cgttttttga gctaataccg aaggtcagct gattgaacac cgtttaccaa gaggttgtga
    42181 gcctaccatt taactccgaa tcacaagaaa taatttcaaa aacaacttct cctgtttttg
    42241 gttcggttgg cttattatcg agaagtagct actgggagtc tatttatcaa aaaaaggaat
    42301 gcgacatagg tcacacccct tttttatttt ctttgaaaca tctttcggta ctcgacagca
    42361 tacaagacaa aagattgtaa aagaccgtaa gtgatgacgg caaaaatgac tctcacccac
    42421 agcgttggta attctgggaa aagcagcaaa aggatcatgc caacatagat gacagcagtc
    42481 gctactttgc cataccactt cgctccactt aatttgatat ttttagatag cccgattaat
    42541 ccagctacaa acataaagcc ttcttttatc aagaatagac caaacaacag ccaaagccac
    42601 ggtcgatacc atgccataga caaaatcaga aaaagttgtg tcaatttatc tgcaaacgga
    42661 tcaagcacct tccctaagtc tgttacctga ttatatctcc gagcaatgac cccgtctaga
    42721 taatcagaca aacctgagac aacaatgacc gctcctgcta tataaaatga ctgtctcagc
    42781 acaaaataaa gataaatcgg cagcaaaaaa atacggaata tcgataaaag attcggaatc
    42841 gtttgtattt ctttacgcca gtctgtgctt aatttcattt tatcgcccta cctcctcagc
    42901 actcttttct ttttatttta gcttacacgg ggaataaaac caatgatttc actgttttta
    42961 tttttcttta cagacactga tattatgagc taatttgaga taatcacttg ctgttttcat
    43021 cgtttactct tctttcttcc tgtcgtttgc gcatttcttt tactagtact ttatgagctt
    43081 tttttgatcc tcgctctagg tcacgctgcc gtttacgtgt tttataatcg ataaacagac
    43141 tgtctaaatc gtaacctgtc gggtacagat cttctgctga acgcaccaga cgaacacgct
    43201 gacgaggcac gtggattatt tttttgtcta aatatacatc aatcgtatct tcacctatat
    43261 cttcataaac taacgcttct ttttggtatt cattgacaaa tatccgatca ccttttgcaa
    43321 agagctgacg ttctttttta ttctccttcc tatttgtaac tgctgtctta ggaagaaatt
    43381 cttttttctg tgtccgatag gctttttccg ccaagtaacg ctctgcttga tggatcaatt
    43441 tcatcgacat atccatttta tgagcaatcc acaaagcttg gctttctcct gtttcttcca
    43501 acccgcaact gatatttagg acgaagtgct tcccgatcga aagccatagc agccggcaca
    43561 aaatcttcat gatctccggc gaatttcttg atttctccat aatgggtcgt ggcaatgatc
    43621 aatgcccctt gctcatacat agattccatg attgcgatcg ctagtgcagc cccttcattt
    43681 ggctctgttc cactgccaat ctcatctaaa agtaccaacg tattcctttt tatctttttc
    43741 aaaatagcag cgatgttttg catatgacca gaaaatgtac tcaacgcatt ttctaaattt
    43801 tggtggtcac cgacatcgac gaaaatctca tcaaagacag caagctctgt cccttctttt
    43861 gccggaactt gcataccgaa catcgccatc aaagtcaata aaccgactgt cttcaacacg
    43921 actgttttgc ctccggcatt tgctccggtg ataatcaagc ctcgatagtc tttaccgatt
    43981 tcaacatcca atggtaccgc atgctcaggt aaaaatggat gtctgccttg cttgataatg
    44041 atatgttccg atttattgat tctaggtgtg cttccattga tttctcggct aaattttgcc
    44101 cgagcaaaga tgatatctaa caccgtgatc gtttcgatca ataaatcgat cacttcttcg
    44161 ttttctgcga tagcaccagt caatgccgcc aggacttgat attcttcact gatttcttca
    44221 gcttttaaca actgatagtg ttcattcaat ttagaaatca cagttggttc aataaaaacc
    44281 gtcgttcttt tatttgattc atcgataatc gttccatcta ttttattttt atagctggct
    44341 ttgataggaa tcgtatagta ttcgcctttt tgaacaatca ttgcttcttg gatcatttct
    44401 ttgtttttcg gatgacgcaa gaatttcagt aattttgact ggatttcttt ttcgattagt
    44461 tgtaattgtt tgcgtacttt acgcaaatta cgtgacgcgt cgtcactgac tttattattt
    44521 tttattttct ggtcaatcaa ctcttctaca tttatcaaat caggaagatg tttgctataa
    44581 gcaaacaaca agggtgtctg gtattgattc ttatcaaaaa actttgtgat catccgactg
    44641 cttctaagaa aatccgcata ttcgatcaaa tcggttggct gcagaatcaa cccttttttg
    44701 acttgttctg tcagtgcatc gatcctcggc aaccccataa atggaacatg ctgactgctt
    44761 tctaagatca agcgtgcttc tcttgtttct tcttgacgat ccaagacagt ttgtaggttt
    44821 gtcgagaccg tcatatcgct gattcgtttt ttgctatagt ttccaattgc tcttgcttgg
    44881 atttcctttt tgatccgatc aaattgtaat tgactaatca tttcgttgtc catattctct
    44941 ccttttcttg aagagatacc tgtcccaaaa taaataaggg cctagagata aataaaagga
    45001 tagaacacag cttaaaaaag tcatgtccta tccttattag aatacaaaga tattgttttc
    45061 ctgacaggta ccgtttcata agcacaccaa ataaactttg tttattggct attcgactta
    45121 ctgattagat accagctaca ctcacaaaac ataccccatt cttctaggtc ttatttattt
    45181 tccacttaac tatagcaaga cacattttgg ttgtcaaact ttagtatgtt ttatagattt
    45241 acaccattaa tgaatagaca cctaccgcga taattgctcc gatcattgga cctgcgattg
    45301 gtacccatga atatgcccaa tctgaagttc ctttattagc tattggcaat accgcatgtg
    45361 ctaatcgagg accaaagtcc cgagcagggt tgattgcata tcctgttggc cctcctaatg
    45421 aaagaccgat ggctaagatc aatccaccta cagcgaatac gttcgttcca ggtgcaaatt
    45481 cgttttgtcc aaaagctagc aacccaagaa ctaatacaaa tgtaccaatt aattctgtga
    45541 tcacatttgc tggataattc cgtatagcag gacctgttgc aaacgttcct aaaatcgcgc
    45601 tttcatcttt cgttgcattc caatgtggca aataagaaag ccaaacaaga atggcccctg
    45661 caaaagctcc taaaacttgc gcaatgatga aaggaacgac aagattccaa ctaattgccc
    45721 ctgtcatcgc catagctaga gagactgcag gattcaaatg agctgggccc atgaatccag
    45781 aaatatagac agccattgtt acagcgagtc cccaaccaaa tgcgatgaca atccagccag
    45841 aagcctgtgc tttacttttg tttaaattca cagccgcaca cacaccatct ccaagcaaaa
    45901 ctaggatcag tgtcccaata aactccccca tgatttgagt catatcactg ttcatttatt
    45961 tctccccctt tagttcccgc agatctgatt ctgcaatcaa tgcttctaaa cgtttagtct
    46021 gttgcgcctt ctcctcttct gtccattcaa aatatccagc aattgcatcg atcacaggtt
    46081 gcttgatctc atcaagctga tctcgttcaa acaacagatg atttgtacga cgaatgagat
    46141 aatcgcctgg ggccaaaacc atttcttctt ctaaaccata acgtaaccga gctgactcag
    46201 cgagactcaa accaggataa ggtgccattt cttttgctaa ttcaaagata cgtcgggcat
    46261 tagtcccgta aaaatcagcg atataagtag catcttcttc ctctaaaccg gctgctactc
    46321 cttcttttgc taattctgtc actgtttctt ctaatttagt tggatcgaag tttccacctg
    46381 aaatctgata ttttttagag tcgatttctt tcgtctctat tccgtattct tcttttaata
    46441 attggcgtat caatcgcaaa gctccttctg ccatcttacg gtaatcggtg attttcccac
    46501 cagataaagt cagcaaacca tctggttctc tttctaaaga actacctctg gaaatcgtag
    46561 aaggtgcttt ttcatcacgg ctgttttcca aatggttcaa cacgtcttct acttcagcac
    46621 gagaaacttt gttttcctta tattcactta ctgtatcgac aactttattg aagctcttgt
    46681 ctgaaatcga tccattatct ccaccattgt aatcagaacc agaattacca atcaacagtg
    46741 gacgaagtcc tgcccagctt gcttcgatat cattcaatgt gatatttgct tctggatagc
    46801 gatgattgat cacatccaat agataatcta catcttcttg tgtgactttc ggatccgtaa
    46861 aatctccttg gtaatccgta tctgtcgtac caaagtaagt cttgttttct cttggaatag
    46921 caaaaaccat ccgcccatct tgctttcctg tatcgaagta tgtgggttgc ggtacaggca
    46981 gttttttcgc atctacaact aaatggatcc ctttagttgg acgcatttta ggagagactg
    47041 gacgcgtaaa attcaagttt cgtactttat ctacccaagg accactcgta ttgatcacta
    47101 attttgcttt gatttcgatc acttcatctg tcagcaggtc acgagctttg acgccaacga
    47161 tttgatcgcc atcatataaa aagccaaccg ctttcatttt acttactaga taagccccat
    47221 cttcggcagc ctttttgata ttatcaatca ctaaacgggc atcattgttg cggaaatcta
    47281 gatagacacc cgcgcctttt agcccttctt ttttcaaaaa cggttctctt tccaatactt
    47341 cttctggtgt cagcgtataa ttctcatatt tggttcctgt cacatttgcc agtttgtcat
    47401 aaaggtccat tgctactttg accgagaaca tattgaaggt tgttgctcct tcgccctcat
    47461 agattggcaa aagcattgga tctggttttg ggatgtgtgg ggcaatactt tgtacgactg
    47521 cacgttcacc aactgtgtca gctactactt ccacatcaaa tgtcttcaga taacgaatac
    47581 cgccatgaac aagtttggtc gagcgagagg aagtcccttc tgcaaaatcc tgcatttcga
    47641 tcaatcctgt tttgattcct gatgctgctg actggactgc cacaccggca ccagtgattc
    47701 cgccaccgat gatcaacaga tccaattctt cttgctgcat tttttgaatg ctatcttgtc
    47761 ttgtcttgtt tgaaaacata tggatttcct ccttattcaa atgcttgggt agcttttact
    47821 gcttttttcc aaccgttgta aagtttttct cggcgctctt cctccatttg aacttcaaat
    47881 agcttgccag cttcataaaa ttcgcggatc tcgtctgtat ctttccaata accgacagct
    47941 aatcctgcta aaaatgctgc ccctagcgcc gttgtttcca agttttctgc tcgttggatc
    48001 ggtacattca agatatctgt ttggaattgc atcagatatt cattgtttgc tgcaccgcca
    48061 tctactttca atacaggaat cttgattcca gtgtcatctt gcatcgtatc gatgatatct
    48121 ctcacttgat aagcaatcga ctgtaaagta gctttaatga tatcttcttt tgtcgtacca
    48181 cgtgtcaagc caaacatagc ccctcgtgct gcctgatccc aataaggagc acctagccca
    48241 acgaatgcag gaacaacata aacctcatct tcgcttgtag agcgtttcgc tgcgtcttct
    48301 gaatcgctag ctttttgcaa catttgaagt ccatctctca gccattgaat cgaagaacca
    48361 gccacaaaaa tacttccttc taaagcatag taaacctttc catttatgcc gtaaccaatt
    48421 gtcgtcaata aattattttt ggataattgc ggtttttcac cggtattcat gacaataaat
    48481 gaacctgtac cataagtatt cttgaccatg cctggttcga atgccatttg tccgaataat
    48541 gcggcttgct ggtctcctgc catccctgaa attggtgctt cgcttccata aaaatgataa
    48601 ccttgcgtat aaccataaac ttctgagtta gaagtgactt ttggtaacat cactcgagga
    48661 atatttagta aatctaaaat ctcctgatcc caatctagct gatggatatt gaacaacatc
    48721 gtccgactgg cattcgagta atcagtaaca tgtgcttgtc catcggtcag tttccatact
    48781 aaccaagaat cgatcgttcc aaacatcaat tcgccttttt cagctcgttc ttgcgcgcct
    48841 tctacatgat caagaatcca gcgtatcttc gttgctgaga aataggcatc gatcactaac
    48901 cctgtttttt cgtggaaaaa ttcttgatag ccttcatttt ttaagttatc tgcaattcca
    48961 gctgactgtc tggattgcca aacaactgca tgatagattg gacgtcctgt atctttttcc
    49021 catattactg ttgtttcacg ctggttcgtt atgccaatcc cagcaatctg atttggtttg
    49081 atccctgatt cgatgaacgc tccggcaata actgactgta cagaattcca gatttcattt
    49141 gcatcatgtt ccacccaact ttcttgcggg aaatattgcg tgaactcttt ttgagaactg
    49201 ccgatgtgtc ttcctttctt gtcaaagata attgctcgtg agctagttgt accttggtca
    49261 atcgccatga tatacgttga ttctgtcatt gtgattccct ccattatatg caaacgcttt
    49321 ctttaactac tcttatcata ctactgtttt aaaaaaagaa actgtcaaaa ttttattctt
    49381 tttttctttt tttgacagtt ttttattatg aagctatttt ttaatcaatt cttttctttt
    49441 ttcagcgtct ctattcttct tttcaatcga ataatgtcgt aaggtgacgc aaattctgac
    49501 agataatatt cacactgttt tttgtttctc tggcaaaatg tgatcaccaa atcatattct
    49561 ttaccttctt cataacttcc aatctcaata ccgccgattc ccctcagttc tctgatcaga
    49621 tattgttgaa aagcaatacg ataaatcggc agactttcta aatcgattcc aatcactact
    49681 ggttttgcaa tataaaaatc gatcatcaaa agaacattgg catactggat catcaggtaa
    49741 ctaagctcac tatcttcagc tcttttcctc ggcaattgct gcaccgctgt ttcctgtaat
    49801 ttcgccagta actgtgttaa ggaatgcccg agcattttct gctgctgttc caaaagccga
    49861 tcacgctcat agacttcgat ctttccaaca aagaaaaacc attcattgtt gatctgggaa
    49921 atttggtagc ctactgcctt ttcttctttg attttcaaac gacgaggacg ataatgccat
    49981 aacatcgttt cccgaatgta agtatctaaa acagcggttg gtaacttttt gctccgtgtc
    50041 aaatcatact gataaaatat ttcttcgtct actatcgaaa aagaaacaaa aaagctgtaa
    50101 aacatcattg tttcgtatac attcagttct gctgctgttc gactaagatg catcacgatg
    50161 attggatcga ttgcttgata aagccggtcc gactgataga gtaatttctt ttctttcaaa
    50221 gttgcgtacg tacttttttc attcaatagt ctttttttcg taatcccgag ccagcaagca
    50281 atctgtgctt ctgctgatgc cgtaaacgtt gtttctaata cacggtccaa tcctagaatg
    50341 aacggtcttt tttctggtgt attttgcaaa aaaagcggtc gctgatcttc cgggatatat
    50401 tggaatagtt cataataaaa atatcgtatc tgtagctctt ctccgtataa ttgaccgttt
    50461 ttgatttgta atccaaattc ctctaagagc tggttcaatt ctttgatctt tcgaaaaaca
    50521 gaagactcac tgatattaaa cgctgtcgct aatcgaacga tggatacttg ctgatgttct
    50581 aataaataga cgagcatctt aaacttcaag ctttcctgca ataaaaacaa tagaattttt
    50641 tccaaactta catcttcgtc caacacaagc agcgcctgat actcatttcg ctgtacttct
    50701 actttttttt ccatcattcg gccaatcaat tcaatatctt ccaaatattg atcaaacgag
    50761 gcttttgaca gttggacatg ctctctcaaa ccattgatag aggctgttcc cccttgcaga
    50821 acaaggtttc gcaaaatcag gatctgtaac tgctcttttc tttctaataa tgcttcaatc
    50881 ttcataggca gtattcgcca cctttgacca caccatatct ggcacacggt attctggctg
    50941 gaaaaatagc tcatgttctt ctaactgttc aaacgtccat ccttcttcta ctgcaattgt
    51001 cagttggtca agaaggtgga acatctcttt tttgctttgg agctgtgctc caagaatctt
    51061 tttttcagaa tcaaatagaa atttgagttt aactttgctt tgatttattg ctgtaagctt
    51121 gtagtctacg tatcctgttt caattttttg gggataaaaa atgctctctt cttctgtcaa
    51181 acctacgctt cctaagaaat agccaaacca ctgattgccg actggacgat aggttccctg
    51241 atcctttgtc tgtgagccac taattgtctt gctgacattt cgtgctgtac ggacagcgtt
    51301 atttactaga gaaacataca ttttttcatt tgttggacga aaagttactt ggatcgcatc
    51361 gccaatcgca taaacgtctt tttgagacgt ttgcaagtag tcatctaccc agatcgttcc
    51421 atcatcattc aatgttaatt gttcttccca catctgattg tcgggacgag aatgattagc
    51481 cagcaaaaca agatcatagt tctcctttct tttttccgtc tctacaatag cggtttcatt
    51541 ttcggtcaaa gacacaactt gttcttctaa aaaaagtgaa agcccttgat ttttcatttc
    51601 ctttactaac ggttctgtca tttcaggatc tagataacga aaaagaattg actttcggct
    51661 ttcgtaaaga tggatttgtt tttttcttga tgccaaccct tcagctattt cgattcctgc
    51721 ttgtcctgca ccaataattg caattttctt tgcattcatg atcttttgct gaagagccgt
    51781 tacgttttgt atctttttaa ctgggtgaat aagcgttgat tctgcagaaa tatttcgaaa
    51841 cttttgattt gaaccagtcg ctagaatcaa acgatcaaaa tccaattttt ttcctcctgc
    51901 taaaacgact tttttttctt tcaatcctat tactgtcttt tctgtgtaaa catggattcg
    51961 atagcggtca gtcagttctt ctttcgtgat ccaagaaagt tgtttttcac tggtaacctt
    52021 tccttttaat atcaaattga acccgctggg aatccatcct aacttcgatt gcttttcaat
    52081 caaatatatt tcacttgttg gcatcaattg gcgaagataa atagccgcat gaatccctgc
    52141 aaacgacccg ccgacaatta caatgttcat ctgcattcct ctttcttata aggtgttcta
    52201 ctgctaactt ctcaatcaga aaacacagta ttcataactc gctttcaacc ttatgataca
    52261 tagcgatgca gcagaatcaa ccctctccat cataccgtgt tctaggtctg cttctcaata
    52321 atgtactagt ggacctaatt gaagagtatc atttctgaag agatgtttca aaaaatgtac
    52381 tcttataaaa gaaaaaaact cgccttttac gtacctctgt ccaaatagga aacagaaaag
    52441 aacgaaaaga cgagttttag cgtgtgtaat gtaatagtta gaatagacac atcatttatt
    52501 tttaattctt taatgcttca acaactgctt cgcctaattg atgagcagat tgaggatttt
    52561 gccctgtaag aagccgccca tcaatttgaa ccacttctga aaaagctgct ccagactgat
    52621 agtttgctcc tttttctttc aaagcatctt ctgctaagaa tggtacttca ttcgttgtac
    52681 catttgcttc ctcttcttca ttactgaacc cagtcactgt acgtccagct aaaatagatt
    52741 ttccagactc atctgtaact ggcaacaatc ctacaacacc gtgacaaaca gctgagacca
    52801 gcccttcatt tcgatagatt tgtgaagcga ctttcccaag atctattgct tctggaaaat
    52861 cccacattgt tccgtggcca ccagcataat aaaccgctgc ataatcattt gcatccacat
    52921 catcaggacg taaggtattt cccaaggccc gatttctgaa atcttcatct tcataatagg
    52981 cccaatcgat ttcatccata ttcaaaacac tttgcggttc taaaggtaca tatccgcctt
    53041 taggactgac aaaatctgca tcgatcccat tttttactaa tacatcataa aaatgagtca
    53101 gttcacttaa ccacaaacct gtaggacgct cgatcttttc gtacttttct acatttgtta
    53161 atacgatcaa tactttcatt ttcccatcct ctttctataa aaattgcgtt attgataacg
    53221 tgctttcaag aaattatata atgggcttgg caaataaagc tctttatatg cttcttcaaa
    53281 aggtttcgtt acaaattcat cctcacggtt ttccaataat ttctctgccc agtcaggatc
    53341 gacgatcatt tgctgtccaa ttgctgcaag ttctgcatat ttcaatacct gctctacatc
    53401 ttcgcgattg cggatcccac cgacaccaac taaagggatc tttccttgaa tcgtgttatg
    53461 gaccacttca agaatcgatt tatcgttgta tttatcagaa cgagctattc gatcatacat
    53521 atttaatgaa acatgcagat aatctagttt tgactcacgt aatcgttcaa gaagccagat
    53581 cgtgtcttca aaacggatac ctggtgtttc atattcttct ggtgagaaac gataccctac
    53641 gatgaatggt tttttagcat attgttcaac cgctgagaaa accgttgtta ataattcttc
    53701 aataaaacga taacgatttt ccaagctacc gccccattga tcctctcgtc tattcgaatg
    53761 cggagagaaa aattgttgga tcaaatacgt atttgctcca tgcaactcga ttccatcaaa
    53821 tcctgattca atcgctctac gtgtggcttt gccaaatgct tggattgttt caacgatttc
    53881 ttcttcactc attgctcgtg gtgtttccgc atcaggacgt tttgctgcaa ctgcacttgc
    53941 agatacaggc tgttctccag ataaagttgc tcgacttgtc attcgtccac cgtggaaaat
    54001 ctgaataatc gcttttgcgc cttctccttg gattgctttc gctagctcac ttaatcgagg
    54061 aatcatttca tcatgagcga tgctgagttc acctggccag ccttttccga tatcttggac
    54121 atttgcagca ccagtaataa cagcaccaag acctttagaa cgttgtttat aataagtgat
    54181 ctcatcttcg gtgatcactc cattgaaaaa gctgagttgt gtcgtcatag gcgacagcat
    54241 caatcggttc ttcaattgaa ctcctgaagg taaagtaatt gattgatcaa attgtgacat
    54301 tgtcattcct cccataattc gctctgatta acctatcgag aatcatctat cattaaacca
    54361 ctcgattagt tgtacatgca actaatttgc ttaaaaaatt ttattttttt tgtaacttat
    54421 ctgttgcatc attcattgtc tgggctaatt ctttacttgc ttcatttccc aaaactgctt
    54481 tgtatgactg atgaagttct tcccagctac catcgacttc cttagcaaat tggcgtcctt
    54541 gttctgtaag ataaactaat gacaagcgac cttcgctaac tgttttgacg tatcctttat
    54601 attctaattt ttcaacaaaa cgagcaatcg ttgatggggc ggaatagagc atttgtgcaa
    54661 tatctttttg tggtattcca tctttttctt ttaatatcaa taaaataaaa ccataagttg
    54721 gtgccagacc tgtccttcta aacgcttcat cagctaattt attcaacatg cgatctagct
    54781 ttttcacgct aaagaaaaga cattcatcta acgctttttc aattggcttt tccatttcat
    54841 cccctccatt ggcgtacata tcatagtatg atttttattt tttgtcaaaa aacacggaat
    54901 aatgtccgcc tcctctgtct agatttgaaa aaaagaagta gccatcttca aagaatttcg
    54961 gcttgttttc gacaaaactc cttctggaac accgtgaatc agaggttgtg aaaaagtcgt
    55021 ttagttttga gtatgaagaa aaattttgtg aaaatggctt tccacatttt tgcataaatt
    55081 tggcttaata ccgaaaaact ggcttttgaa caccgtttat atcagaggtt gtgaaaaagc
    55141 cgtcctgcat caagtaataa gaacagccaa acaaaaatag ttcctcatat tttgtcgttt
    55201 tttgagctaa tgccgatggt cagctgattg tacaccgttt attgagaggt cgtgagcctg
    55261 ccgttgaact ccgagtcaca aggagcaatt tcaaaaaaca gcttctcatg ttttatgact
    55321 atggtgactt gtgatcgagg agttggcagg agaatactgt ttattcgtaa agaaggggct
    55381 gtgacaagac ttttgtcaca gtcccttatt tccttttatt ataggatttc gccatttgat
    55441 tggatgactt gtctgtacca atcaaatgat tttttcttta accgtttctt tgtgccattc
    55501 ccttcgtcat cttgatcaac atagatatat ccataacgtt ttgacatttg tgaagtagaa
    55561 gcgctgacga tatcaatgca gccccacgac gtataaccaa ataaatctac tccatctttg
    55621 atagcttcct tcatctgctc aatatgctgc ttcaaatagt caatgcggta atcgtcttga
    55681 acggttccat cttcttctac tttgtctata gctccgagtc cgttttcagc tatgaacagt
    55741 ggtttttgat acctatcata taattgattc aaagcaattc tcaaaccctt aggatcaatc
    55801 tgccagcccc attcacttga tggaagatac ggatttttaa ttcctccagt tattaagttt
    55861 ccttggaccc cttcccaatt ttctggatga gcactgactg cactagacat gtagtagcta
    55921 aaagaaacaa aatcaacagg gtaggctgct aagatttctt catcacctac ttctattttt
    55981 aagttgacac ctttttcttc aaacattcgt tgcgtatacg ctggataata tcctcttgct
    56041 tgaacatcac taaagaacaa agaagttctt tgctgctcaa ttgttttttg aatatcatcc
    56101 ggatcacaag aatacggaac aagaagctga tagctgatca tacaaccgac ttgtgaacct
    56161 ttgataattt catgacaagc ttttgtagct aaagcacttg ctataaactg atggtgtgca
    56221 ccttggtatt tcgcttgttc caaatgggga tggttttctt caattactcc tacgctaaca
    56281 aaagggtgat gttttacaca gttgatctca ttgaaagtca tccaatattt tactttattt
    56341 ttatagcgtt tgaatactgt ttcagcgaaa cgaacgtaaa actgaataag ctttcgatta
    56401 ggccatccac catattctgt aaccaaatat aacggcattt cataatggga aagagaaacg
    56461 actggctcaa tcccatattt tagacattcg tcaaacactt gatcataaaa aaataatccc
    56521 gcttcattgg gtgtttcttc atcaccatga ggaaaaattc ttgtccatgc gatagacatc
    56581 cgatagcatt taaaacccat ttcagcaaat aaacggatgt cttctttaaa gtgatgatag
    56641 aaatcatttc cgtgtctttt aggataataa tacttgctgt tgggatcctg cgccgctttt
    56701 acttgctgat gcgtcatcat atgccattga tctgtccatt tttctttagg taaatcgctg
    56761 tcgaatgtat acacatcaga cacagataat cctttttcat ctacatccca tgcaccttca
    56821 cattgattgg ccgctgtcgc tccgccccat aaaaatcctt ctggaaattt tttcatatcg
    56881 atccccctaa acttgctagt tttcttgttt gattattttt cttatgacta gtaatgatat
    56941 ttttgaatct actactattt gtaacaataa ccattgtggt cggatcatat ccctctttga
    57001 ttaattcttg caaatctact tccatcaata aatcgccttt acgtactttt tttccatcag
    57061 atactgcact ttgaaagtat ttgccattta aattcactgt atcaataccg atatggatca
    57121 gtatctctgc tccttcttca ctgactaccc caattgcatg tttcgttgga aaaactgttg
    57181 aaacttcccc gtttacagaa ctgtagattt ttccgtccgt tggaatgatc gcaaaccctt
    57241 ctcctaaaga tccactagca aatgttggat cgtttacttc agataaatca attatttcac
    57301 ctgctgcagg agtacttaac actatatcct ttgaggattc ttcttcgatt tcatccttgt
    57361 agccgaaaag aaaagttagc atacaggaac tgatcatcgc taagaaataa ctagcaacta
    57421 gccaaacaaa tccttcacca atataaatcg ggaaagacaa aatacttctt gtagcaactg
    57481 ccaaagcacc ggctcctgcg gcaccagcta ctccaccaaa tatagctcca catatacaag
    57541 caatgtaaaa tggtcgttta tatttaagag tcacaccata aacagcaggt tcagtgattc
    57601 caaataatgc tgtgataaat gcagataaag ataaactttt tactttctta tttttcgttt
    57661 tcaaaaatac cccaagtact gctcctgctt gcgcagctac ggcagtcata catgctggac
    57721 ctagcgtatc acgaccgtag aaagaaagat tgttggtcat tactggtaca agtccccaat
    57781 gtaacccaaa aatcactaac acttgccaaa atccgccgat aacagcacca gataaaacag
    57841 ggctaaagtt ataaacagct aaatatccag ctgcaatcag ctgacttgca taatctgcaa
    57901 ttggacctac aactaataaa ataattggga ccatcacgat gatacaaatg aatggtgtca
    57961 ataaatttcg aatactttcg tgcaagcttt tgcgaatctt aggctcaata taagaaagaa
    58021 cccatacagc taaaattgct ggaataaccg tacttgtata ccttgctaga atcacgggca
    58081 tccctagaaa tcgcaaggtt atgctatcac tatatgcact gacaatcgta ggataaacga
    58141 gagctgctgc aataaccata gcgatgaaac gatctgtatt gaactttttt gcagcagtat
    58201 atgccaaaaa tataggcaag aaatagaaaa atgcatcagc tgctgcattc aaaatgatat
    58261 aagttcctga ttcagtagtt aataaattca aactcgtaca taaggcgagt actcctttga
    58321 tcaaaccact tcctgccaag acgcctaaag tcggggcaaa aacagcggcg atcatgtcta
    58381 taaaagagtt taaaatgcct tttttctcag ttcctctctt tccactagat gcatcatctt
    58441 ctagtttcat ttgtttggat aatacgtcat acacttcatt tactgcattt cctactacga
    58501 cttgaaacat tcctccagct tcgactacag tgatcacacc ttctagttgc tctaccttct
    58561 ccttatctgc cttcttatta tcttttaggg taaagcgtaa ccttgttgca caatggtaaa
    58621 cattgctgac attttcttcg cctccgacaa atcggacaat atctttcgct aattgtgaat
    58681 agtccatttt tacttccccc ttgttaatta atgccgtagc aatccttctt acaagataag
    58741 tatagttctt agaaaacggt ttctccattc aattagtacc ccttctaata gcgaacgaaa
    58801 ctgtacaata gtgtgtatgg tttacttagc cgagcaaatc actcactgct tgaaagaaaa
    58861 caagtatatc gtttctctta tagtcaaagg agacaaaaaa aacacgcttg atcttccttt
    58921 gctgatgtat aagtggtatc tcaagctgat actctgtgat ttttgtttct acttggcttt
    58981 tgataagaca gcacaacaaa gtctcggcat ttaacggaag cataactagg tcagaactag
    59041 gagagattag ttgctgaatg gaatctatct ttttatggat ttttatttga ttttcttctt
    59101 tgtagtaatg atcaagcagt tttgttttct ttttttcttc aactatggtc agcttttcac
    59161 gcaaaatctg ataaatctcc caagattcaa actcatctag aacactaggt agataaatca
    59221 aatcatccca ctcaaaaata agctcttgct cagtagtcaa aattgcatca tattccgtta
    59281 ttttgtttga ttgatttttg aaaagataca ctggttctat ccggcattct ttgatccaca
    59341 tgttcatact ttgttgaatc tgttttttta gtgtattcaa aatactaatt ggctggttac
    59401 taacaatcag tatctcccct tgttttcgaa aaggattcaa cgcttcggca agatacaaaa
    59461 caaaataagc gctttcagct aaattgggac gtaattgaaa atgtattggg aagaaacgcc
    59521 gaattaaata aatttctaaa ggataacggg agatgatctt ttgtacaaaa tgattcatgg
    59581 tattatgtcc ggcatccatc ctcgttttca tttgtttgat atgggttagc aaaaattctg
    59641 tttcatggaa caataacgaa acaggaagat ctaaaaaacg aataatcgtt tgctcaaatg
    59701 ctcttagatt cttctctatt tctttgtttt tttcatcatt aatcatcaaa taatttaact
    59761 ctaatagtcg attttcaatt gcttgttttt cttgattgga aaaagaatag ggtagttctg
    59821 atgataactt ttttgtgagg gtctctacca tcggaataaa taatgtatac ctgtttgttt
    59881 tttctaaaag ttcttctctt cgaagaatgg tcaaaacgag ataccgagaa aatcgtatga
    59941 agtcctctcc tgaaacaata taattatatg atataagaac ctcttttaat gtcttttgga
    60001 cagtcggcat gatattggaa aaaattgtac tgatttgttg aggcaacctt gcgtgttgga
    60061 tcaccgtttc tgttccaaca agagataaga aaattctttt tgaattttct tcagcaatga
    60121 tttttagtcc ttttgtcgac gaaacttcca gttctaattt aggattgcgc tcgatccaac
    60181 gcaaaatcgt ttttatttgt aatgatacgg ctgtttttga aagaaagaaa atgtctgcta
    60241 tcttttgcat actgacatac cctttttgaa acaataagta cgtcacaata gttgaagctc
    60301 ggaaatccat gctggaatag attttatgtt tcgtcacctc ttgtatgatt tgctgtttag
    60361 tttcagattc aattgattct aaaaaataac ctgaacgttt atttgactgg ataatgattt
    60421 tcttctcgta gatagcaagc atatttttga tttcagtttg gatcgttttc ttgttggtac
    60481 ctaaagcttc agctaattct tcgcttgtta tccaatgatt cttatttctt aatactacaa
    60541 gaatttggag ttgtcgttta tttaagtcca tttgcttaca cctcctcttt gttataaaca
    60601 tacaggaaaa acctctcaaa tgacaatagt cacttgcaga ggtttaaaaa tcatttgaag
    60661 aaagatctat attcaaggtt tttaccatta gactggataa tttgtttata atattcaaaa
    60721 ctatcttttt tcaatctcct aaagcttccg ctcccatcat tttgtctatc cacataaata
    60781 aagccatatc gcttcctcat ttcccctgtt cctgccgata cgatatcgat tggtccccac
    60841 cataagtaac caatgatttg gcaaccatct tttattgcct cagcaatttc ctgaagatgt
    60901 atttttagat actcacaacg ttttggatcg tggattcgat tcaattcatc tggtgcttca
    60961 tctagtccaa tgccattttc aactatgaat aatggtaatt cataacggtc tgtcaattca
    61021 ttcatgacat aacgaaaccc tagaggatca attggccaac tccaaggttc gggagatttt
    61081 tccttcaaaa agggattatc gaaaccattt gctccgccag tatctacgcg catttctgct
    61141 tcttttttat agacagcgct acgataataa ctaaatgcaa tataatctgc cgtgttagct
    61201 tgcaagcact gttcgtctcc atctaacatt actggtgcac agtcttcttc cttccatgtc
    61261 ctgtaaatat aagctggata atgccctcgg cacatgacat cggagaaaaa ccatgaattg
    61321 cgtttaaatt gcagtgaacc aaatacattc tctggatcac agtcatatgc ataagtcgct
    61381 aatgcagaaa agctacacat aatacccatc ttagcatttg gatcgatttt ctttaataat
    61441 tgagtagcac gggcgttcgc tagaaacata tgatgacagg cttgataaat cacttttttt
    61501 gttagtgtag caatgggttc aagtttatct ctagcaggga atgtaaccaa tccagcagct
    61561 gcataaggca tacgaaaagc attattgatc tcattaaagg tcatccaata tttcactttc
    61621 ccttggtagc gttcaaagac ggtctgcgca taaaattcaa aaaagtcgat taattttcga
    61681 ttttgccacc ccccatactc tcctaccaat gctaaggggg tttcataatg actaagagta
    61741 attactggct cgatatcata tcgatttaat gtattgatta gtctgtcata aaatacgaga
    61801 ccagcctcat ttggcttctg ttcgtctcct cttggaaata ttcgtgccca tgagatgctt
    61861 gttcgaaaag cttttaaacc taactccttc agtaaacgaa tatcctcttc aaatcgatga
    61921 taaaaatcaa tcgcttcatg agaaagataa tggagtgatt cgtctaaagc aatctcccaa
    61981 atcttttttt cttcattcca ctgaatacta ggatgctggt tcatgatccc gataagcgta
    62041 tctgtcacat taggtaattt gccgtcttcc aaccatgcac cttcacattg attagcagct
    62101 actgctccgc cccataaaaa attttctgga aatatttcct gatccataac tatctctcct
    62161 cgctatcaac aatttcttac ttgaagtata gctcgattca tcaaaacaag atattctaac
    62221 tatttcggca gaagagaaga aaaaaattga atgctactct tcatttttaa tatttatata
    62281 taacaaatac ataagacgat ccccgaaaga aaacactcgt taaccatcta agcaaacgat
    62341 ttattttact tccaacacaa atgcttcata aggtcgtaaa tcaactttgc cgtctggtaa
    62401 ctgtttcaga ggataatttg acacaataac ccttaaagct tcacgtggaa tagtgaacgt
    62461 ctgcttttca ctggacatat tacaaataac gagccattgc tggtcttcat atatgcgaga
    62521 ataggcaaag acatgctcag gcgtcttttc cactaattca tagtctcccc agacgatgat
    62581 gtcatgtttt ctacgcaaat cgatcaattt cttgtacata taaaaaacag aatcttgatc
    62641 tgctaacgct tcttctgcat tgatttcttt ataatttgga ttgactcgaa gccatggaat
    62701 tccagtagta aacccagcat gttcacgggc gttccattgc ataggcgtcc tagcattgtc
    62761 tcttcctttc gccttgattg attccaagat ttcctctttt gtaaatccag aagaaatcct
    62821 ttcgttatac atattgattg tctcaatatc ttttgcttcc gcgatatcat cgattgggca
    62881 attcgtcatg cctaactctt ctccttgata gatataaggg gtgcctttca tcatatggag
    62941 caagatagca aacatcttgg cactttcttt tcgatacaca tcgtcatttc cccaacgaga
    63001 aacaattcgc ggaagatcgt gattattcca aaataaacta ttccatcctt catcacctaa
    63061 agatgtttgc catttggata atactttttt cagttcagag atactcaagg gtttcaaatc
    63121 ccatttgtct ttgccttctt gctgatctaa tcctatgtgt tcgaattgga agaccatgga
    63181 taattcattt cttttaggat tggaataaag tttagcgatt tcggtagttg ctccccatgt
    63241 ttcgccaaca gtcatcagat ttttgtcacc aaaagttgct tgattcattt cctgaagata
    63301 ctcatgcagt ttaggtccat tacttgtgat ttctttatcc ggttctttgc caatcatatc
    63361 gatcacgtcc atacgaaagc ccccaatacc tttatcgatc cagaaattca tcatttgata
    63421 aatctcttgg cgaacctgtt tatttttcca attcaaatca ggttgacgct tgctatacaa
    63481 gtgcagaaaa tattgccccg ttttttcatc caactgccaa gcagaaccac tgaatattga
    63541 gcgcaatcta ttaggctctt ttccattgac cggatcacgc caaatataat agtcccgata
    63601 aggattttct ttatttttac gggcctcaat gaaccacgga tgttcatcag aagtatgatt
    63661 caccaccaga tccatgatga tacggatatt tcttttcttt gcttcttcaa tcagttcttc
    63721 catttcttcc atcgtaccga attctgccat gattgcttga taattactga tatcataccc
    63781 attgtcatca ttcggagact cgtatactgg agaaagccaa attgcatcaa tacctaaata
    63841 cgccagataa tccaacctgg aaataatccc ccgcaaatct ccaataccat cttgatttga
    63901 atcttgaaaa cttcttggat agatttgata aacaactgaa tggtgccacc atttttgttc
    63961 catgattttc ctcctataaa tggatgtttc tattttttgc ttaatcattt attttagtct
    64021 ctctcactaa aaattgtaac gctttcaaat agctattgca ccttgttatc ggtaacagaa
    64081 taaaacaaaa aaacagctga ggaaattccc tcaactgttt tttgaaagga ttgatttatg
    64141 cagggaagaa tgctgatttc acaacttctt tataaacggt gttcactcag ctgtcccttg
    64201 gtattagctc aaaaaacggc aaaatataag aaactatttt ttcgtttttt tctctaatac
    64261 tcaggccaga acgctgattt cacaacctct ttatttcaca ttcaatatcc acatgaatcc
    64321 cacaaataca aagaacagac catacatgat tggagatact tcttttcctc ttttagctgc
    64381 taacatggta attggataga agataaaacc taatgcaatc ccatctgaaa tactataagt
    64441 caaaggcatg ccgatcaaga tcaagaatga agggatcgca atctctaagt ttccccattc
    64501 gatttgtcgc aaagattgtg ccatcaatac tcctaccata atcaatgctg gtgcagttac
    64561 ttgtgaagta acaactgata gtaatggaga aaagaacaag cctaacaaga agaaaatccc
    64621 tgtagtaata gctgtgatac ctgaacgtcc tccaacggcg ataccagctg atgattctac
    64681 aaatgcacca acaggagaag taccaaataa ggaacccgca agcatagctg ttgaatcaga
    64741 agctaaagct ttccctacac gaggcatctt gttgtctttc atgaaacctg cttggtttgc
    64801 taatccaact aaagttcctg ctgtatcaaa gaaagtcaca agcaagaatg tcagcactac
    64861 gacccacatt tgaagagaat tgatgtcccc tacatgtttt aatgcaacta aaaatgttgg
    64921 tttcaaactt ggtgctgcgg caacaatttc agaaggcatt ggaatcaaac ctgtgaccag
    64981 acctaaaatc gttgtagctg ccatcccgat gaagatgcca cctggtacac gccgaacaag
    65041 caagatagca gttacgacta atccaaaaat cgtcaaccaa gtagaaccaa cgttgagtga
    65101 tcctaatcct actaatgtag attcattcga aacgatgatc ccaccttcgc tcagaccaag
    65161 gaaagcgata aatagaccga taccgccaga aatcgcatat ttcaaatctg ctgggatcgc
    65221 atcaatgatc atttcccgca gcttgaagat tgtgatcaaa ataaaaatca aagaagcaac
    65281 gaatacgccg gctaatgctg tttcccatgg aatccccatt cctaaacaaa cagaataagc
    65341 aaaaaaagca ttgatcccaa gagcaggtgc cgttccaatt ggataacggg ctaatacccc
    65401 cattaaaaca cagccgatcg cactggctaa tgcagtcgca gtaaacactg ctccttcatc
    65461 cattccagaa gcacctaata cagttggatt tacaaataag atataagcca ttgagataaa
    65521 tgttgtaaat cctgccagta cctcacgttt taccgtggtg ttcaattttt ctatttcgaa
    65581 gtaggaaagt attttttcct tcatcttcca tccccctaaa tccgaacatt ataaataaag
    65641 tccgttaaaa tttcgattta ttaataaaac aacgtgtttt atcatatact aaaacaaaac
    65701 ataagtaaac aaaaaattcg gattttaagc aaaatccgaa cgttccatct gattaaatcc
    65761 ctttatctca aagttcatga acattcactt tggattacaa gaatttcttt attgtgttaa
    65821 taaagtttct tcattctagt ctcaaaaatc aatagtgtga tttgatttta ccatttcgtt
    65881 tctgttcttc tttgatgaat tcttttgtat cgacaggatt cagattattt agtccgccaa
    65941 aacctgtatc gaccattttt ccccagcctt ttgtcttctt ttttcctgat ttgagattct
    66001 ttgctcgaag cttctcacta tgttttgctc gccgatactt caaataacct tctaatcttc
    66061 ccattagatc cactgttttt cctccttttt attcaatcag acgactcagc ttttcctata
    66121 acaaaataat tgccttcagg gtcagaaaaa ttgaaagtca agatgccatt gttatctgtg
    66181 atttctcctg gttcttccat gttctcgtag atagtttcaa attcatccgt aaaaaatact
    66241 aaagaaggcg gtggtcctaa tacctctggt gaaaacttct gcacaaatac ttttgggaat
    66301 acgcctaatt ctaattcttt tgagatgctg agtacaatac tcttaaattc ttctggcaat
    66361 tcgattgttt cagaaatttc tgcaccaatt ttttctacaa agaatcggca aatcatctct
    66421 acgtcattga cataaagcat cacacgtgtt ttttgtatca tcatttgacc cttctttcta
    66481 tttgattttc tttcctgtct ataaactgat tccattatat cacgaaagcg caaacacctt
    66541 gtgtttgata ctattcaaga aaaataaagc aatagtttct aggattgctt tcctccacaa
    66601 acttttttta caaaaaaaaa aacggcaatg aatgccgctc ttcttatttc gattctttta
    66661 taattctgct tctgattcat ctttggttag tgtgtgtcta acactagtta cgccaaatgt
    66721 ttgatcgatt ttttccttca acgcttcgat tgcctgtgcg ccacgtgccg cttgttcagc
    66781 attgatggat tcaatgacca gcaccgctgc ttgtgtttct tccgtcagca tcgttctttg
    66841 ggcttcacgc cagttgagac agcgacagat cgctccttgt tcatcatagt agatgatttc
    66901 ttccggaagt gccggagcat cggaatctgc acctaaaggc aggaatgatt cgccaccttg
    66961 ggcttttcct aaatgcagat ttcctgcgat cttttcgata tcttctccgc cgcaaggtac
    67021 gccaaaagac aaggaaatac tattatagat atctacaagc ggattgattg ggaaaaattc
    67081 ccgttcttga tttgcacgtt tcagtaaagc ttcaatagaa gaacgtgcac cttttttagt
    67141 cttgaatgtg gtaaatgcct gacgccactg agcaatgact tcgttttggc tgaatgtttc
    67201 ttctgtaagg taatttcttg cttcttttgc tgcctcattc aataattgat gatacgtttc
    67261 ttcactttct tttgttacgt ggttatcgat accatttacg gataagattt cgatggttgc
    67321 ttcaggaaat acttcccaga aattggtatc cactattact tttttcatct gttcacacct
    67381 cttgattaga ataattgctt gatgaataga tagtctgttt ggggatcatc tcccatataa
    67441 aaaacatgtt cgctgtattt gataaatcct tttttacgat aaaaagcgag cgcaacatcg
    67501 ttgtgttccc aaacaccgag ccaaatggct gttttttgct tttcttttgc tttttcaata
    67561 gctgtatcta gtaaaaatgt accgatacct tgatgtttaa atttttttcg tacatagatt
    67621 cgctcgattt ctaaaaaatg atcagccatt tcctcagatt gactcgttcc tgtatttagt
    67681 ttcaggtaac ccgcaggctc ttgatcgata ctcactagga aaaaatcggt ttctttatct
    67741 tttagctctt ctgtaagttt ttctagtgca taagcttgtg tcaagtaatc agctaaatgc
    67801 tccggtgaat tatcttttcc aaatgtatct gtaaatgttt cgatactaat ttgttgtagt
    67861 aagtctacat ctgaaggcgt catttttcga atttcgtatt tattcacggc ttcttccttt
    67921 caatagatcc ttttattgcc ttttttgaca aaattccaat cttcgctaac attcttgcat
    67981 actttattta aaagatattc caattgtttt gcttcttcgt cagaaagacc atttaatgcg
    68041 actgcattgg agtagttgtt ttctcgaatg atgaaaggat agatttctgc tcctttttta
    68101 gtcggataga gtttcttgat ttttttattt tctttatctt ccaaacgttc gatcatccca
    68161 ttggattcta atttcttgat tgctcgggca gtcgttgtac gatctacttt gatcatttct
    68221 gctagttttt cttggatgat tccaggattt tcgcaaatac gtactaaata aagatactgt
    68281 cctcttgtta aatcgacttc tttgaattcg atattgctaa tagaatctag cgctcgggca
    68341 atcattccga tgtctcgaag gatttcagcc atttcatccc acctttattt tgtttgtaag
    68401 actagttcac ctctttttgt tgcaaatgca actattttca ataaaaaaat caagttcttt
    68461 tttaataact agtaaagtat attcttttct tcttttacga aaaagctcaa tcacaataga
    68521 tctggttttt gttttctaaa ataagtaact gtttcttcgt tgttcgcttt tctgatagct
    68581 ttggcaactc ttctatacta aaaaatccca tgttggaagt ttcattattc tcaataaact
    68641 tggcctcttc accgtggatc gcacaagcaa aaacaagttt ataatactga aaaagctgtg
    68701 gaatatcttt ttgtttattc gtatcaaaaa ctgctcgcaa ctgagtagtt tctactgtta
    68761 atcctgtttc ttcatagact tctttacgca cattttcttc aggagacaat cctatttcag
    68821 caaatccacc aggaagtgac cattctttcg tccgtttatc ttcgattagt aggaccttgc
    68881 catctttttt gatataggca cgaacatcta cttttggtgt tggatgtcct tctccaatcg
    68941 ttgtgagcgc ttttatttct tcgaaagttt cttttcctat ttcactgatc agttccaatg
    69001 aaatcgtccg gatctcctca aaacgctctt tatcaaatac atcttttcca taatatagac
    69061 cagcttgaga aagtgcgagt agtcttttgt attgagccaa cttcttgttc attctcttcc
    69121 cttctttttt agcaaatgta tgactatgta atcaagtata gaagactggt ttaattacgg
    69181 caaataaata taatgaaatc tgcaataaat aaaagaatgt taaaaaactc gagaacaaaa
    69241 gacattcgac ttctctgggg ctgtgaataa atggcgttca aaagcttgca tctgcggtaa
    69301 taagccccac caaacgaaaa atatgacgag ctattcttgt ctggctgttc ttattaattg
    69361 aggcaggaca gctttttcac aacctcccca ctaaacggtg ttctcctacc aactcctcgg
    69421 tcacaagtca caatattcat caaacatgag aagctgtttt tttgaaattg ctccttgtga
    69481 ctcggagctg aacgacaggc tcacgacctc tcggtaaaca gcgttcaaaa gccaattttt
    69541 cgatattaag ccatttcttt gttacttatt gtcattgatt tctttttcta atttatccaa
    69601 tagtggagtg taatccactt gagtatagtc tgttacatca aattcatata gtgttcctaa
    69661 ctggaatttg tcatattttc ggtcggcgat gatctttttg aatgcttctt tcgtaatatg
    69721 attggtccct ttcgttcgat cttccaatac gtcaccatag tgataatgat ccatgatata
    69781 gctcaaatga cgatctgatt cacgatcacg tttgtaccga cgttgccata acacttcaaa
    69841 gtctgctgtt aggcgaatcg tgatcacctg atatccgtat ctatctgcta attcttggag
    69901 tcgtgctttt tgcttatcac taaaaggata ctcggacaca atcactttct ttcctgcttc
    69961 catatacaaa tcaagtgctt tgtaatagaa aggataaact ttcgtccttt cttgttccgc
    70021 ccgttcttcc aaattgttaa acccgatgga ttctgcatag tattccttga tttcatcgag
    70081 cgtgatggca tacatatctg gaaatcgttc ccgtagttta ttcataagat atgtttttcc
    70141 tgtaccagga ctaccagcca gaagaatgaa atactttttc atctcattta tttcctaagt
    70201 taattggact ttccaagttc ataaacagtc caatcttatg cttgacaatt tcttttactg
    70261 cttcatttgc tggaatcaca ttatggcgaa gagacttgtt gatttctgtt tcactaaagg
    70321 tttctttagc tactttcgtc cagttgacta aaagctccgt tccaacattg aatttgcgga
    70381 tcccgttatt gatcaattca ggataatctt cttctttcac acctgttcct ccatggataa
    70441 ctagggggac atcaactact gcatcgattt ctttcagcaa gggaatgttt acttctgttt
    70501 ttgatttgaa ttgtccatga ttcgtaccga tagcaatagc taatgcatcc acgcctgtag
    70561 cttctacaaa tttcactgcg tcttccggtc ttgtatatac cttgtcattt tcagcgacat
    70621 ggattccttc ttctgtaccg ccgattgttc caagttctcc ttctacggaa acaccgtgcg
    70681 catgggcata ttctactact gcttttgtct tcaggatatt ttctttgaaa ggcagatggg
    70741 acccatcata catgacagaa gtatatccgc tgtcgattgc ttctttgata tcatcaaagt
    70801 ctcgggcgtg gtctaagtgc aagactgcat caaccatttc ttcttctgca atagctgtca
    70861 ttacattgac taacacatgc atgccgatat atttagcggt atcgacactt gtttgaataa
    70921 tgatcggcga acccatttct tttgctgcgc ctagcatagc aggaagcatt tctaggttat
    70981 gcgtattaaa agctccaact gtaaaattca actcttctgc tgtttttgtt acttctttca
    71041 atgttgtata catcttttat tgccacctta tctttttatt tgtttccttt gatcgttact
    71101 tgttttgcaa tttgtcgcat ctcatccatt ttgcccatgt agtaatcgat cccttgatca
    71161 tcaccagcac gagcagcatc tgcacgcttc tggttataga ggctcatcag ttttttatac
    71221 ccatctccga tcgtctgttt attttccaaa ctcttttcta aatattggat ggcttgatcg
    71281 ttcacataca attcagaaaa tttaagtcca acttgttcat aaagtttcgc taatttatgc
    71341 ttatcttggg tagtggaaat ctcttgtttc aattgtgtaa tctctgattg aatcttttcg
    71401 gtcgcttctg gcgatagggc tttttcttct tttgccagaa cttttttcgg ttctttttct
    71461 tttttcttaa aaaatccaaa catcattttc cctactttca attaaaatgc tttcaaaact
    71521 gggcttaaga tccaggcata taagagtgct gcggctactg tatctacatc ggttgctgta
    71581 gcattgatga atcccatcga attaaagatc gttactagca aagcgggcaa taatgtaata
    71641 aagaaaccat gagcaatacc gccaatgatc gctcctcggc gtccgccaac tgcgttgcca
    71701 aatatccctg ctgtccctcc ggcaaagaaa ttggttagca taccaggtaa aatcatcgct
    71761 aagccgaaca tgggcaaagt aaacatggca ataatcgtac caatcgttgt cgtaatgaaa
    71821 cctaaaatga cagcatttgg gctataagga aagaaaactg gacaatctaa ggcagggatc
    71881 gcatcaggaa ctaatttcat agctatccct cgaaatgccg gcacgatttc acctaacagt
    71941 agacgtacac cagctagcaa tacatacaca cccactacga attggatggc ttgtaaaaag
    72001 gcaaacatga tatagttttg atctcctgat aattcagaag cgaatggttc gcctgcaaat
    72061 aaaacagtga tgatatatag cgggaccatc acgaccatga cagacaaata agtatcttgc
    72121 agaaattcga aatgtgtcgg caacttgata tcttcgatcg actttttatt ttcgcctttc
    72181 tcaccaaaaa gcttagcaac accggcttca aataagtacc cgatcgtaca aaaatgacct
    72241 aaagcaatat catttgatcc agtgatttta cgaatgatcg gttgcgctac tgccggcata
    72301 gcaatggcga aacaagctcc gataaaatca ccgaccaaga tcaatacgat ccctcgcaga
    72361 ccggcaaaat agccaaagac tgtcgtcatc gttgccatcc ataaaattgc ttgaccagtt
    72421 aaaaaaatgt acttccattt tgtgaaacga gccaaaataa tattgaatac aaaaatggct
    72481 aagaacgtca gtgcaatatc tctacctaaa cccaaatcat tcattgcttg accattgata
    72541 gattcaatag aagggatgat cccttgcata tgaaatcctt cagtaaagat tttcccgaaa
    72601 taagttaaac ttccaacgat gatgctcgaa ccggcactca acacttgaaa tcctaggagt
    72661 gtctttaacg tgccagagat gacttgtcct gctgatttct tctgcagtag tagacccaac
    72721 atagcaatca atgcaatggt gatcgatgcc tgagtcaaaa tattttcgat gataaaattg
    72781 ataacgccca tgtttttacc ctcttttctt tttgtattta gataactccc ttatcttgca
    72841 gaactggggt gattttttct tcaatttcat tttttgaaac aatatttttc aaatagatca
    72901 tcgccgtttt aggatcaact gcgaactttt cgaactgcga acgaaaattt tctgctgtga
    72961 tgatcacatc tggtttcatg gaaactgcgg aagaaatatc acaatggtcc agtttggctt
    73021 ctactcctaa tttgttcaaa acatcctcag cagacatctg tgctgcaaaa ctacttccta
    73081 aacctgcacc gcatacgaat aaaatgttca atttgttcat ctttgttctc ccccgtatca
    73141 tttattattt ctcaactact gaaaaaagca gttgtttgaa atcttcgata tttgtgcatt
    73201 caatcaatcg atccaacttc tcttcgttgt tgatcaattc aattagttct ttcatgatgt
    73261 tcagatgcga gtaggagtct actgctgcca aacaaaaaat aatctttact ggatccattt
    73321 caggattacc gaaatcgatt ggttgctcaa tcgtagctac gctgactcct aatttattga
    73381 ccccatcttc tggtcgggca tgggctagtg ccatgtgttt gccaatcacg atatacggtc
    73441 cgtaatcatt cactgcacga atcatcgctt cgacatagcg ctcttcgaca atgttttctt
    73501 taaccaatgg tctagcagct agttcaatcg attcctccca agtagtggct ttttctttga
    73561 tcatgatatt gctgtccgtc aaaatatctt ttaacatagg ctggatctcc cttttgttga
    73621 tttctaaatt gtttgtttcg aataattttt ctaacttgcc atagatgatt cgatctactc
    73681 ggccaccact ttctttcatg acatctatta tttgagtgaa taactccgtc gattcatgac
    73741 tgttaggctc taaccgctgt agttcttcat ttcttttcaa aaagtcttct ataaccaaga
    73801 tattcgtctc agttaaaatc ggatcgacaa ctaaaagcgg cttatttcga taattcaatt
    73861 gaaaggtgct gaaaaccaga ttgacatcca atttatctac taattcgatt tcttttgaac
    73921 ttaaaactgc agtaatctcg atctgaggaa acttttcttt cagattctct gctaacagat
    73981 ttccagtagc catcccatgg ttacagacaa cgactgattt ataaacataa ttcaagtctc
    74041 gcttgattac actggcgatc gtcgaaaagt ggatgacaag aaaagctatc tcgtcctcca
    74101 gtatcttgcc accaattact tcttcgatcg taggaacaaa atgagtgact gcgcggtaga
    74161 ttgggaaata atttgttcgg atgttttctt tcaatggatt catgacttgg atatgattct
    74221 tgattcttac aatcagtgca gccatgtgct tatagagatt ttcgaataaa gcttcttcct
    74281 ttagatggaa aggtacgtgt gtctcgttct ctacaaattg gatcaattgg atcgttagta
    74341 attgagcttg tacccactcg attgaattgg agatatctct agcattgaac gtctcaatag
    74401 tgaaacgaag ataatttctt tctacttgcg ggacattgtc caattgaaat tcctcgatca
    74461 tgtggtcaat aaatgcagaa aagctactgt cttttatttc tgtatttttc caattaatgg
    74521 cagagataaa ttcatgtttc ctgattcgct ggatccagat caatgtaaaa agcaggattt
    74581 gttttttata aatatcatct tcttgtttca acaacttatt ggaatagatc tcctgtattt
    74641 ttttgatttc caccaaagga aaataatgga gaaagatttt ttgagccggt gttaattgtg
    74701 catcttgatt cataaagaag tcggtcattc ccagattctg attgataaaa tcatagatca
    74761 tcgtacggat agatcgttct gaacctttat aaaccagtcc ttgctttcca taactgacga
    74821 tctctatccc ataactgacc agtgttgctc gtaaccgtct catatcttca tctaatgtac
    74881 ttttagagat ttgaaattct tcttcttttt tgtttagatg gatcgggatt cggctgtaag
    74941 caacggctaa aactagatca aaaatacgtt cgcgccgatt caaaaagccg tctttcacat
    75001 cttttatttc agtttctaat cgagcttgct tttccttttc cagcttcaac aaaaaacctt
    75061 tgttgcgaat tgtacggatc tccggaagct ttttactgct caaccagata ttcgcttcaa
    75121 gaacttcctg acggatcgtc cgctgactga cattgaactc acttgctaga tgttttgctt
    75181 ttactggata ttgggctgtc atgattctgt gaagtatttc aattgttctt gttttcatag
    75241 aaatgatctc cttctgattt caagtatatg gttccgctta cataataaaa agtagatatt
    75301 tctgccactt gaagtggaaa gaaagtaagc aaagcaaaca aaaaataagc catatgcttt
    75361 ttcatctcct caacgaaaaa gacatacgcc tattattaca aaaattttgc ccatctatac
    75421 aaaaaagagg ttgtgaaaaa gctgtcctgc atcaagtaat aagaacaact aaactaaaat
    75481 agtgcttcct atttttcgtt tggttgttct tattatcgca gatgcaagct tttaaacacc
    75541 atttagtgga gaggttgtga cagagatgtt cagccttgag cgataagaag cgattttgaa
    75601 aaatcgcttc ccatatttta caaaatcgtg ccttattgcc gataggctat ctctggcaca
    75661 ccgtttattc agaaaaagga gctgcgacaa ggcttttgtc acaactccgt tcataaatat
    75721 ttcctgtcaa tccagcataa tcggctgaat aaaatcggct tgccatcttt tttctttctc
    75781 agaaaaatca aaataccata tctgagaaaa atactgtcgt tgtgtcttac ttcctgagat
    75841 caatcgccca tcttttcgat cgactgaata atcacagcat ctgaaatcaa ttcggatggc
    75901 aaaactattt tcgtggatct gtcgataatt tcctacttcc tgaatagtta tttttttagt
    75961 atgatttctt acaccgtctg ctttgttttt ttgcagaact ttctgatgtt cggcaaacag
    76021 cttgtctgta taacagcttc tggctttttc aggagtttct tcttcccaag cggattggat
    76081 cttcatgaat atcttttgga tttccagaaa ctgtgctttc ttttctttag ccgttcctga
    76141 catgcgggac aatatctccg ctttcagcct tttcttttgt cttttattct tgacgataga
    76201 aaaagcagaa acccctccta ctgacaaaac agctaatgca agaaatcccg tttgctcata
    76261 actagaagga cctgtacctg gaccataata cccataagaa tctctgccgt aagaacgact
    76321 gccaaaataa ctgcccccat atgaacgacc accaaatgaa cctctgcccg aacttcgacc
    76381 gctagatgta cctccaccat gaccacccgc gacagcgaat ccttgggtcg gcagagcaaa
    76441 caaacatagg cccactaaca aaatgattgc taaataattg atttttttca ttgtcttcct
    76501 cgttatcttt tattacaaaa aactattttt atgatagcct tgctaaaagg aagagtcaat
    76561 aaccagatgc ataaactgtt tttttagcaa ttttgtctta tttagtcatt gagtaacatc
    76621 ggacaaatgt atgtgtcggc agtccataat tcctctatct tcagcatgaa caagcttgca
    76681 gacaagagat ctgcgcttcc tccaggagag atttggtttt cctgacaaaa gtgcaacagt
    76741 gctgtaaatg gacgatttgg taaagcactt tgactagcag catgagcaag tttttgcatt
    76801 tccactaacg ttttctgatc actgcgatgc aatacgcatg tgtcatctag cgaactcatc
    76861 aaaactaaca acatatgcat ttgtttctgt acatatgaat cattatctag ctccttagct
    76921 gcttgaattg caagcctgat atgcggatac cctaatatcg cttcttcata tgcaccattt
    76981 acgccatatt tttgcttcac cctatgacca tgagtggttt ttttatgacg atattttgta
    77041 tcaggaaaag cagcaagctt gctgacatca tcaagtattt tcgataaaga aaaaggctgt
    77101 tccatactga ttttttgtgc aatgacactg atcaatagcc ccattgccca aatcgctcct
    77161 ttatgggtat tgatgccatt tgtagcaatc agcattgcct tttccgcttt tcgcccaatc
    77221 tcagcaattc tttctcttaa ctcctgatca atagcatgat gccatgctat ttgagccatt
    77281 tcttcaaaaa aaggagttag cgtcttagca gacttaagaa ataaagcata gtccatatcg
    77341 gaatgtgcac ccgcatccag tgcatccact aatccaggtt ttggacttaa tgttacttct
    77401 gcgatcaatg cttcctctac caacgcagcg agttgctgag tcactgcttt ttttcgttcg
    77461 tcatttatca tgacactcac tccttcttcc tactattact tgctgaaacc ttttttgata
    77521 gctacccaaa tgatatgaag taaccagctt aaagcaaatg cacaacttgc cgtcattaga
    77581 taagctacaa gaatcatgac tcctgaaggt aactgcagcc aactatcttt aaacaataat
    77641 aacagtactt ggaaaacaaa tacattggct aaatacgtac gataagcata aacagacaac
    77701 catttgaaca atggcaattt tggcgaatcg tttacaatca ttttggaagc gcctatgaag
    77761 acagcaaaga tgatgactaa actgtataaa ctttggatcg tattcaagta aggtgcattc
    77821 gcaaagctca agtctcctgg atgtgcgagc aatgaacgga cagaaaagaa cgcgataact
    77881 aaggcaacag gtaagaaaag ataacgtact ctgtccaaat attgatagac tttttcgtga
    77941 taaacaaatg cggctacccc ataaatcatg aaactagcaa caaaccgatc taataagtac
    78001 cagctgtcat gataaggccc agtcaatact tgtgtttgat agaacagata ccatgcgaca
    78061 tataaaatcg ttgaaccaat caatactggc catacatatt ttttattagc aaatactttg
    78121 taaccgagcc aaacaaaaaa cggcatgaac aattggatct gcagcatcat aacggtatac
    78181 cataaatgag gcgctccatc acctgtgaca tatttcagta aaaagcttgc agtatccgta
    78241 tacggagttt gttgttggac tgctggaaat agccaaagat aagccgtcgt ccatagaaga
    78301 tacggaacga ctagttcaaa aaacttttct ttcaaaaatt cccaataaga caaatgctga
    78361 cttgttttta ccatattata aacaattgca aaaataaaca ttggtgctgt gtatttaacg
    78421 atgacgtaaa aggtaccaag aaaagctgta tttgttgcgc tgtggctgtt tgccaaagca
    78481 aagctcaata tcgtttgcat cataacagcc gttacagctg atactttctg gaagtcactt
    78541 acgttgattt tgattttttt gttttcaaac atctctttct ctctcttttt ctttattacc
    78601 aaagttcttt ggttaattta ggtccttcga ctgttttcaa tagaattttt ttctctggct
    78661 ctctcaaata ctcttttagt gaaaaaccgc cttgccgagt cactacttgg gtatcgaatt
    78721 gctcaaaaaa agcaggatgc gattgaatta cctgaattgg caattcaatc ggtgaatttg
    78781 cgtacagcag caaatcaaaa tcactggttt cttttactgc cggaatccca gtcgataatt
    78841 caaatcctaa gctgccgccg attccccatt tacatcctga taatatgttt ctagcagcat
    78901 gaaattgctg ataaacagga taatccatga ttttctcttg tctatacgat tcttgttcga
    78961 tgatgtccca cggatgaatg acttgtttga cggcatgttt tgagatttct gttgaccatc
    79021 tctgattgcg ggcaggtcca cgtaaaccaa tcggtagtat ttctgcgtga tccgtcgacg
    79081 cacgacgaac tgttccgaac atcttttcag ttagaacgac ccattcaggc aaggtgaacc
    79141 cttctatttc atgtttatca aaaaggacaa tatcatgtgc ttgaatcatt ttttatgcat
    79201 cccattcttc gtccattttg gcacggactt tatttgtttc gacacgtccg aatgttttgg
    79261 ctgtttcgtt tgtgtatcga tttgtcagca tcgtgtcatt tgtattgcgg acatcttgaa
    79321 tggcttcatt gattgcttcg atgactttgc tgacattttg ttctgaagca gcttggtcgg
    79381 tgatatcttc taggaaatga tagatcgctc ctagttttgt ataattattg atatcgtaag
    79441 cgatagctgg aactttttca gcagctgctt cgatttcagc aaccgaacgt tttgtcacac
    79501 gtgcagcact ttctttagac atcgcttgga cggtaatttc tttattgttt aaagcaatca
    79561 agcggcttga ttgtaatcca tgtgctaaaa atgcacctga aatagcattt cctgcaatca
    79621 atccaataac tggatgtcca agcttgacgg agttttgcat aagcagcagc actattagcc
    79681 aaagccacat ggataccgat caattcttcg ttatagccgt atgcttggct tggtacatcg
    79741 atcacaacga tgattggccg tttcactttt ttgtctttat cttcttcgta aacgtgatcc
    79801 aaaatttgtc ccatgcggaa accttcaact aaaccaactt caccgtttcg tacacggtac
    79861 atcgggtttt taggatcagg tacgattgat gtcacgatgg cttcttctat gaatttactt
    79921 gatttaccat aatacacagt actaatagaa gaagttggat ttttcatgcc agttagtgcc
    79981 gcaaaccaat cgtaaccaac acttgctgca gctggttcat ttccttctgc tacttctggt
    80041 aagtcaattg attttgcttg atggttagca attgcttcat tgtaatcgtc aatggccatt
    80101 ggttttgaaa gatctaaaga atcaagtaat gataaataaa atgctgagct ttcactgcga
    80161 tgcgtgtctt ttcgttcgtc cattgctgcg atgacagcag ctttgattgc ttctacacta
    80221 tcagtcacta attcatcaat gatttttgat tctacccgtt gacgagatcc taatgtattc
    80281 caaatcaagt ctttgtcact agaatcaaat tctcgaacgc ctgcttcttg ttcaataact
    80341 tctggtccat tcaaaccgac tctcgctttt tttgttgcga ttaaataact cattaatgct
    80401 gaagtaatcg acataccgcc aaatgatcct acacgtcctg gaatcaaacc gatgactggt
    80461 acatattgtt ttagagcaat gattacattt ccgatttctg aaatagataa cagtccgtag
    80521 tttgcttctt gcaaacgaac accacctgta tctagtacaa tgactggaaa gatctcattt
    80581 ccttttttat tttcttctaa cacatgttca agtgcagcaa cgatttttgc accggaaact
    80641 tcaccgatac cgccaccttg gaattttcct tccatagcga ttactactgc ttgtttgcca
    80701 ttgatcgtgc cacggctgac aacgatcccg tcatcacttt cagggacgat tccttgtgct
    80761 ggtaaacttg gcgcgatgat ttgatcgaat ggatcaatca attcacgtcc attgtcaagt
    80821 agagcgttca ctcgttctct ggcgtttaat tctacaaaac tatttttcat ctgaaagttc
    80881 ctccattgct tgcgtcaatc gtaggtacac aactcctggt gtagcaccga agtcattgat
    80941 cacgatatct gctgaaattg gataacgatc aaaaaatctc gttaatacat tgttccatac
    81001 ttcgccgaag ccatcgcttc ctgtacaaat ttttacagta gattctgttt tttctgttgg
    81061 aaacatcaag atttccaaat ctcctgaacc gaccactcct acatggattt tcttattgat
    81121 cggctgtttc gttggatatt tataagctaa ttgttccatg gatctctccc ctttttgtaa
    81181 aacagagcat acacgttctg cttattcgtc tttcttcttc catctgggta aatggcgaca
    81241 aaaggttttt ctcgccaatt ttatgaccaa gttctgaatt tcattggtgg ttcatacagg
    81301 ccatctgacc attcgatcaa atcatcgatg gtttgtgcag ctaataatga acgtttcgct
    81361 tcactacgtt tgatgcctag atcttctggt aatttcacga tgccggctgc acgcaagcta
    81421 tctagtgatt ctttcgtgct agtcattcca agaggtgtaa caccgccaat tgctgcaatt
    81481 gctgcttgtc gttcttcttt tgtttttgct ttgtacaaat aagcaattcc ttcttctgtc
    81541 acgatatgtg tagtatcttc gctataaatc atcactggtg cattggctaa gcctgcttgt
    81601 ttttgaacag ctagtgcatc taattcttcg acaaagactg gttttttatt tgaaccatat
    81661 gtttcaacca tttgaacaac taatttttgg cctttcccta atggatcatc attgtcgcga
    81721 agtgattgcc atgctggtgt agaatgacga cgaccgccag gattatgtcc catgttaggc
    81781 gcaccgccaa aaccagataa acgtcctttt gttacggtag aagagtttcc ttcgtaatct
    81841 aattgcaagg ttgaaccgat aaacatatcg atggcatatt gtcctgcagc ttgtgataat
    81901 gttcggttac tgcgcatcgt gccgtcttta ccgacaaaaa agacatctgg gcgagcagca
    81961 atatattttt ccataccaac ttcgccacca aaactatgga tgctttcaac ccaacctgat
    82021 tcgatggctg gaatcatcgt tggatgtggg ttcaataccc agttcttcgc gattttccct
    82081 tttaacccta gtgattcacc ataagttggc agtaacaatt cgatagctgc tgtattgaat
    82141 ccaataccgt gattcaaaga ttgtacgccg tgttctgcgt agattccttt gattgccatc
    82201 attgccatta gaatttgcaa ttctgtgatg ttttgaggat ctcgtgtgaa taaagcttct
    82261 aattgataag gtttatctgc tttcacgaca acgtctaccc agtcaccagg gatatctaca
    82321 cgtggtaaag aatcgacaac ttcgttgact tgaacgatca cgataccatc tttgaaagct
    82381 gcagcttcga tgattgttgg tgtttcttcc gtattgaaac ctgtgtacaa gttgccgtct
    82441 ttatctgctt tatctgcagc tactaaaaca acatttggaa tcaaatcgat gaataagcgt
    82501 ccataaagtt ccaaataagt atggatatca cctaatttca ttgtgccgtc ttcaatcatt
    82561 tgggcgacac gcaagctttg tgcaccagca taagagaaat cgatcttgct tgcgattcct
    82621 ttttcaaaaa tattcaaatg ttctggtcgt gagatactag acatgatcaa atgcagatca
    82681 ttcacttttt ctgcatctac tttttcaaga ctttctgaaa gaaaacttgc ttgtttttga
    82741 ttgtcgcctt ctaatacaac tttgtcgccg ggagcaatca gtttttccat tacttctacg
    82801 attttttcag tttctacata cttgccattg agcaagttgc tgattttttc caatcgctgc
    82861 gctttttttt cgcgtttaga agcccagttg cggtttggtt tttccataat tagtcatctc
    82921 catttttgat atagaaacgt ggcgtcatca ataccatgtt ggtctagatt gatcgtacgg
    82981 atccctttat ctacaccaaa ttttgtatga atcagctttg tcaaagtatt gccgggggga
    83041 aattcaatcg tcagatccat tcctaattct tttgccaagt ccatcatttg gttccactgc
    83101 acagggaaag ctaggttttc caacaaatct ttacgaatct cttctgcgtc ctgagtggct
    83161 cttccatccg tattttttat atacaaacat ctagcatcag atagatggac agactgcata
    83221 tacggcttga atttcttgac cgtatcattc atcaagagac agtgagatgg cacagggact
    83281 ttcagcagct tcgctgtttg cgcttggtgc cgtttggctt ctgccaacgt aacggataaa
    83341 ccttcgatac tcccagataa cgtatgttgc atcggacaat tttcatttga cagataaact
    83401 ggatggtcag gatcaaatgt ttttgctaca atttcctcag cttcgcttct cgtcacacct
    83461 actactacgc ccattgcata accgcttgga taagcttctt tcattaagac tgcgcggtga
    83521 tagactagtt ccgctgcatt ctcaaatctc aaagatcgac aagcaacagc tgcacaaaaa
    83581 gcaccaatcg aatgtcctgc tgcaatatca ggctgaatac cgtttttttc catttcatct
    83641 aaataaaata ctgcttttgt cagtaatgct agctggataa aaaccgtatc ttgatagttt
    83701 tcttctttat caactaaccg ataccccgtc acattttcta aacgttccat gtacatttca
    83761 gggatatccg ctaacatccc taacttctga ctgccttgtc caggaaataa gaaacctgta
    83821 ctcatgagcc tcgcctcctc agcacttact ttttccactg ctatcttagt caatttctgc
    83881 tataataaaa aatgccaaaa aaagaaaaaa ccataacaaa aaggtatgga tgggatggat
    83941 aattatgaaa ttgcttcatc tgcagtattt taaaaaagta ttcgaaacaa aaaatgttac
    84001 ccaagcagcc aaagaattat ttatttctca acctgccttg agccgtgcga tcaaacattt
    84061 ggaaaacgaa ttaggtgtcc ctttgtttta ccatagcggc agaaacattg agacgaccgt
    84121 ttatgcagaa gaattttatc catatgcagt caagacatta gacacattag aagaaggaat
    84181 caaattattg tcttcggtca atgagaagat cgttacttcc gtcatattgt atttagaggt
    84241 agcctctgtt tctattccga acttggtccg aatttttatg gaaaagcatc ctgatatcca
    84301 attaacgatc atgcaacatc atttaccaga tgatattacc gatcctgtac tgtacatcac
    84361 ttcggagatg aagcctggca tgaccaatat tcctatcatg aaagaacctg tttatgtcgc
    84421 cattcctaag aaacatcctc ttgctaaaaa agaacatctg caattagaag atatccaacg
    84481 cacccccatc ttgatgctgt caaagagcaa cgccttccgt catacactgg atgcagcact
    84541 tgaagcgaaa agtatcgaat tgacgatcag ttcgacgaca gatgatcctg cgacattacg
    84601 ttctattgtc aagcaaggat tagctgttag ctttttccca aaagtttctt ggtcttacga
    84661 taaaaatgat cctttcgtct tgcgggaaat caaagatttg cccttgacac gaacaattta
    84721 tttatcttct agcttcacag aagatcatcc tttgatcaaa atgattgcaa aaacgatgcg
    84781 ggaattttat ttaggaaaat aaaaaaaaaa gagctgggac aaaattcttg tcgcagctct
    84841 tttttcgaac aaacggtgtt ccagaagtaa tttcttagaa aataagccga aatttcccaa
    84901 aaatttgaga agcaattttc gtaaattcct tcttatttct tgaagctaaa catttctgtc
    84961 acaacctctt ctctattgtc ctagacattc attgcgttga tttaaaactt ccatcaatca
    85021 aatctgctag ttcatctagc ttttctattt tacgtagatc aatagagatc caatgttctt
    85081 tattcatgtg ataggctgga aaatacccct cttttcctcg caaaattccg ccaagttcag
    85141 gatcgacctt caaatcaaga atattgatga tcctatggtc acttgcatca tcatagattt
    85201 tttcttctgg aacagacatc aggaccccaa accatttttt gcttttttga tgtctgaata
    85261 cgcaataatc aggaaatttt ttaaaaatat attctggaga caaattgtat gtttcattga
    85321 tgtgatcgat tagttctttt ttcgttagca tctgcttcca tctctttctt attgattcgc
    85381 tttattcaaa gataccacgt aagaatagaa aaatgaatac aagtagttgc taatcaaata
    85441 cttcgatatt tttctttttt atcaactctt aaatgttcaa tccgcctgtg ttggtcttgc
    85501 taccatctac tattaaaatg tttattattg tttgcccacc tattttttga ttttagtggt
    85561 atcatttttc aagttcatga tgaaattctt atcatcagta aatgctccag aaaaataaac
    85621 aatgattgaa aaatcagttg aaacttgacc accgtttatt ttctccgtat tcttagaata
    85681 gaagggagtc tgattgatgt attcactaat gaaaaaaatc attaccgaaa aagatattcg
    85741 acgtcatgtt tctttagtag aacaattgct gaatcataca aagataaccg taaatgaatt
    85801 agctgaaatc atagggacaa ccgaacgaac gattttttct gaccttcaat ctattcgctc
    85861 tcagctgccc gaaggctggg acatcatcag cgatcaagca ggaatcagtt tgcaaaacca
    85921 gcaaaattta ttaacaaatg acctttggga gatttttttc aaacaatcag tcagtgtcga
    85981 actgctgaaa aatctgcttt ttacaaaaaa agttgctgtc cctgattttc tagccgacca
    86041 tgggctttct tatgggacat tgaaaagaca tgtgactaaa atcaatcagc gtttagcaag
    86101 ttacgacttg cagatcgatt tgacgaaata tacagcttgt attcttggaa aagagcgtgc
    86161 gattcgtact ttttatcatc gattgctgat tcctttcact cataacaact attttttcga
    86221 ggattattcg atccatgaat cccattattt tcaattttta agaaacctca gtcaaactga
    86281 actagcggtt gaaacagaag agattttcgg aacatgttgg ttctttatca atacgatccg
    86341 tataaaagcg aattgccgat tagattcttc tatccatacc aacagcacac tctcctccct
    86401 gtatgactct gcattgaaaa aattgtattt aacggaaggt atttatctta aagacactga
    86461 gctttctttt gcttctttct gctttctgga aagttggaat tacaacaata actatggaca
    86521 agaaaccgct cgctgcctgc atcattctcc atttttagag gtcctcgaaa cgtttgtaga
    86581 ggaactagct tcagagctgt ctcttgatca actaaaaaaa acatctctga ctgataactt
    86641 ggctctcctc atattaaaat atcatgaatc gccgatattg attgaagcat tggaccgtca
    86701 ataccatcgt tttttagaaa catatgatca gcaatatgca cacttgtatc aacagaaaga
    86761 gaatttactg aacgatctaa aaaaagaaat agaaatcaat gaaccaaatt actttctcca
    86821 actcttgtct ctactgatcc aacaaacgat tttttctatc aaaccgaatt tgttcaatgt
    86881 ctattttatt ttccaaggag aaccttcatg gaaggcgttc ttgcagcagg aattaaaaga
    86941 ttacttagga aaacgtgtct gcttcttacc tatcgaacta accgatcttt ccactatttc
    87001 ttttgaaaaa acagatatct tgatttccaa tttccctcta gattctctag atatccctat
    87061 tgtatacatt tcttctattc caacgaaaaa tgagctcaat cgtttgactg aactcacttt
    87121 caaaactttt ttatagtaac ggctagcgac tgtattctct agctgttttt tcttttttgc
    87181 gaaacagttt gttcatgatc cctttttcta tttctacaac taagaataga agaatcacat
    87241 ttgctccaat caataactgt tgtgtcatcg ttaaacttac tgtaccgatc agctgctggc
    87301 cgactggtag aaaaataacc atcccttgca ataaagcaag gatacctaat gaaagaaaaa
    87361 gcgctttgtt ttgcaaaaga ccttggttca atgacggctt ggacaactct ctgcaattga
    87421 tcatgtaaac agcttgagct aagacgatat tttgcagaag aatggtttgc tgtaagcttt
    87481 gcccttcaaa ctgcatagcc aataaatagg caggaaccat gatcagtagg gagacataga
    87541 tgatccgaaa caaatgataa ccagatagga ttccttgctt tggatctctt ggtgggcgct
    87601 tcatgatttc tggatctggc gactcgaacc ctagtgcata agataaagtg attgtcgtta
    87661 ccatattgac ccataaaatc tgtactgggg acaaaggtag cgggcgattc agcataagtg
    87721 cccaaatcaa gatcaatcct tgagctaatg cagttggcaa gaagaaattg atggtttttt
    87781 gcaaattatc caaaatccgc cggccctctt ttacggcttt tgcaatcgta tggaaattat
    87841 catctcctaa aaccatatca gctgcctgtt tgcttacttc actacctttg attcccatag
    87901 caattcctac atcggatctt ttcaaagcag gtgcatcatt tacgccgtct ccggtcattc
    87961 cgacgatttc tccatttttc tgcaaagctt taacaattcg cagtttatgt tctggtgtcg
    88021 ttcgagcaaa gacatcgact attggcactt gctgaatcaa ctcttcatca gacataagat
    88081 ccaaatcgat cccttctaaa actttggcag tatgttttaa gccaatttgt tccgcaatcg
    88141 cttttgctgt gtctttgtga tcccctgtaa tcattttcac tgagatccct gcttgttggc
    88201 attcctttac agctttgact gcactttctt ttggcggatc gatcaatccg gcgatccctg
    88261 caaaagttaa ttgggttaaa gtctcatgcg tgagttcctg tttcgaatct acttttttat
    88321 aagcaaatcc taaaacacgc tgaccttttc tcgcaaattc tgcagctgtc tgactccatg
    88381 cttcttgttc tgcagaagaa agagttgatt tagcaaataa tacttctggt gcacctttga
    88441 cgtaaatcac cgctcctttt tcctccgcat gcatcgttgc catatatttg tattcagaac
    88501 tgaacggaat ctttgcttct atttttttca aaggtagatt ggctgtttct gtgtgtcgaa
    88561 tcagcgcaac ttctgtcgga ttgccactta aattttctgt tttctgttct tcttttgttt
    88621 ttaattcctg acagtttttc ataatggaca acacgcaggc ttcttctttt gcagctacat
    88681 ccacaactgt catttcattt tttgtcaatg ttcctgtctt atctgaacag atcactgtca
    88741 tagaacctaa tgtttctacc gaaggaagtc ctttgatgat cgccttttct tttgccattt
    88801 catgtactcc aacggataga atcatggtca aaacagctgg caatccttcg ggtaccattg
    88861 acaccaccaa agcaatcgta gccgaaagaa ggatatgcca atccatacca tatcgaaatg
    88921 tcgtaaaaat aactaagaat aggctcaaac aaagaatgcc ttgaaaaatt tgtttgttta
    88981 atcggttgat ttttttaatc agaggcgtcg tttgttgttc gaccgattgc aatgcttgat
    89041 tgattttacc gatttctgtc gtgtttcctg tttctacaac gacaccgact gcagaaccag
    89101 attgtacaag cgttcctgaa aaacccatat ttttctggtc gccgatcgat tcttcttctg
    89161 tcaaaacggc atgacttttt tcagatgctt ctgattctcc cgtcaaaatc gattcttcca
    89221 ctaataaatc atgtgcttcg attaatcgga tatctgctgg aacgacatct ccggcacgta
    89281 agacaatgac atctcctttt accagttctt tcgcagggat tttttcttgc atcccgtttg
    89341 atagtactat cgcttcttgt cccatcagct gcttcaaacc attcaatgat tcttccgctt
    89401 ttctttcttg ccagtaacta acgagtccat tgacgatcac tacgaataaa ataatacttc
    89461 cttcaatata ttcactagaa gcaaatttca aaaaagaggc aatgatcaac acgatcatca
    89521 gcagatcagt aaaatgcttt gctatttttt tccatcgttt tgtctgctgc cttgctttta
    89581 tttcattata tccttgatca gtcaggcgtt tctgtcgttc ttcttgcgac aagccttctg
    89641 ttgatgtttg atagtttttc aatacatctt ctaccgtcaa tctgtaccag ttcatcctat
    89701 cccctcctgt ttaattgata ctgttattat acgcagggaa gttttttcag gcgtatcgat
    89761 tatttcaggg gggtctgaaa taattcgttt tgcaaaatgt atctgggcct aactgatatt
    89821 tctattgctt attcttttat atacaaaatt taagaataca aaccagataa ccaataaaaa
    89881 aggaataaag cgtgtcgtgc tttcgaataa caagctgaaa gcaattgaag taaaaaacac
    89941 caacaaagca agatctttat atctttgtgt agtgttccgt ttcttttctt taataaattg
    90001 aacatgtgca cacaagatcg aagaccacac aaatagaaaa caactcgttg tcatgcctgc
    90061 caaaagctga aaaaacaatc gactatcagc tacaaaaaaa tgtagacaaa gaccggcaaa
    90121 aaataacatt cctgtaatta aaataccgtg taaaggtacg cctttcttag aaagcgcaca
    90181 aaaccaatgg ggcaaacttt tttcttttgc tgtttgatat aaaatcctgc tagtactgta
    90241 gactgcacta tttgctgagg acaaagaagc aaccaaaatc attagattga caattgctgc
    90301 tccgccttgg caatggatca cttgcagcat agtcactaaa ggactttctt ttaaatctaa
    90361 acaatgccat ggaacaacaa ataaaatcga caaaatcgtt cctatataga aaaagagaat
    90421 acgccaaggc agacagttga ttgctttttt caaattcttt tgcggatcac ttgtctcgcc
    90481 aacggttaag ccgatcattt caattccagc aaaactgaat aaaaccatag gaaatgagac
    90541 taccattcca gcaaagccaa acggtagtaa ttcatcgatc tgtccaaaat tttctttgat
    90601 tccgatagac tgggtatgaa aatctgagac actcaatcct atacccaata agataaaaag
    90661 gaaaatcccc aagatcttga tgattgagaa aaaagattcc aattcaccaa accacttgac
    90721 tgcaacaagg ttgactgcca ttaagatcat tagtgcgcta cctccgctta tcaaagctgg
    90781 tacatgtaca aaccagaaat ggatatacaa tcctattgct gttaattccg caagtccagc
    90841 tccaagccag caaagccaat aagtccaatt gacaaaaaat gcccactttt tgcctaaata
    90901 atagtcaacg aaatcactga tagagttaaa tgtactattt gctaaaaata aatcacccat
    90961 ggcccgcatc aaaccataaa tagccaaacc gcatatcaaa taaacgagaa taacagctgg
    91021 ccctgctgat gcaattgcct ttgctgaacc taaaaataat cctgttccaa ttgcgccacc
    91081 taatgcgatt aactggatat ttcgattagt tagagtccgt ttcattgccg gtttttccat
    91141 caagttcacc tttttctttt tcaagcagca tggcgacttc ctgttcccaa gaaggtttct
    91201 ttattttttc aatacagagt ggtactacaa acaaaatgac actgatggct gtgactgcaa
    91261 ttagattgat ccatgttcca gctttcatcg tcagtccgac agaaaatccg attgccgcaa
    91321 ataaaacaat aacgacagtc caaactccaa gattgctctt tttctctttt tttccaattc
    91381 taaatggtcg attcaacttt gcatgtgtat aacgcaatct caaaactgcg atccccatga
    91441 tgacatagac gatacagtag ataacagtag ttgaatttac gagcatcaaa aatgcttgat
    91501 tgacgccagg aatcagcaaa taaaaaagtg caaagattga gataatgaca gactgagtca
    91561 aaataacgga tttggatacg tcaaattgat tcgtcttcca aaaattgaat tttggtggat
    91621 acgcaccttt tctagcactt tctgtcactg tctttgctgg tcctgaggcc caagcagata
    91681 attggactgc tacaccaatg aagacaagta aactaaacag attcacaata agatgtggca
    91741 aaccaagaat ttggcaataa atcgaaatag attgcgcgat attattcaat tccatttgtc
    91801 cttttggtac gacatttgct acaactaaag cattcaaaat attgacgaaa aatataaaaa
    91861 ttaacgcggc aaatactccg cgaatatacg ttttaactgg attttccaat cgagtgatat
    91921 acacagagga catttcgata ccagtaaaaa taaacatgat cggcgcaaaa taaacaaatg
    91981 aggatgcagt cgtagtatct ggtattaatt tgtcccatga aaaactgcct aatgttccgg
    92041 ttggtacgat cccaactttg atccacgcag caaaccctaa taagagcatc atcgtcaaag
    92101 gcacgtacaa tcctaaccaa acaccgactt ttccgccgat ttttgccata tcaaatttca
    92161 aattcaaaaa agtgatgatc caataaacga ctaaaatgac aactaatgta aatttgctgt
    92221 tcaaaccaag cggcacatta tcgataatat taccaaacaa cggagcgagt gctgaagcga
    92281 ccatcaccat cccaggaaac atttggaccc ataacagcca tgagacaacg aacccccatt
    92341 tttttcctag agcattcgat acccaaagtt ctggaccacc tttttgggga aacattccag
    92401 caaattcacc agagatcaat gagattggaa aagcgtacaa taatactgca accagcatgt
    92461 aaaaaatcat cgtccagctc gttgctgcta catctggaat atttcgtaca cttgctacaa
    92521 gggcgcaggt cattccgata aaggtcatgg tcgtgatttg ctttgatgaa ccagtatctt
    92581 tcatctttat tccttctttc aatagcgaca tatgtttttg ttttctttta tttttgttca
    92641 agaacagaaa tgacaaggtt tcatcgattc agtacaaaac ccagtatcac cgaaacatcc
    92701 attgaacgat cttagtgaac tgggtttgat acatgaaacg aacgatccaa cttatagaac
    92761 gttttataaa aaagaatatc ttggcgagga atatatgaaa aacaggggga aatacaattg
    92821 ttttgatgaa gcaaataatt gtctgttctc catatgtctc ttgttattct ttcacacaaa
    92881 aatcagttct attggatgat ttcgtttagt ttcttttcca ttgctttggc gatttttttt
    92941 gtataaaaat tgaaaattcg atcatcattc aaataaggag tcatgatagc cgcacgtagc
    93001 agagtgattt tctgttcttt tttccattct tctttcgtta gacccattct ttcaacaaaa
    93061 cgaatcggag aatcaccgta atcttcttgt gtaaatgtag tatgagaagt aataaaccgt
    93121 tcaccataaa catcgccatc catataagaa caccgatcga acattttttc atttaattca
    93181 ttgatagcgt tcaaatctgt acagccttgt tctttgaata cccaattgac catattaaaa
    93241 tcaggatgat tcaatggata gacttcgatt gtttttcctt taacagtaaa agtcagatga
    93301 tcgagaaatt ctctgaatct ttgagctgcc tcgattgaag ccccaatcaa ttgaccatat
    93361 ccggtcacat tcaatggcaa tacacgatgt gctgtccaga ctgcggcggc ggttgctcca
    93421 gcttttgatc cttccaaaat ataagctcct aacatatctg gagcctttac tgatttttca
    93481 aacacatatg gcgcgaaata agaaatgata tttctcatat ttttatgttt gattacgatt
    93541 cctccagcag cataagggac atagcccatc ttatgaggat ctatcgtgac agaatccgct
    93601 tctgaaatag ctctgaaccc ttcatatacc tctttgtcaa tcgttacgca gtggtggaaa
    93661 acatgatgtt cttcaaagaa ttcagctaag gaagcatacg gcacaaattc tcctgcttcg
    93721 tttagaaaca gtgaacgcgc atagccgcca tatgcggcat caacatgtaa atagaaatag
    93781 atcccttcat cttttaacct ttctcttaat tggacgattt tatctacact gtctacttga
    93841 ccttcttctg tcgttcctac gacagcaacc acacctagaa ttgggatttt ttgtccagct
    93901 aattcacgaa ttgttttttc caaagcatta atatccattc gataatcctc ttgaactggg
    93961 atagcaacca tctgatctaa gccgactccg caaatatcta acgccttcat ccaagaatag
    94021 tgttttgttt gagggaccag ccatttccct aatctttgga tattttttcc gctacgggaa
    94081 gaagctgctt tgacctcatc catttcttcg tccgtaaagc tttcggtcat ttccaaaatt
    94141 tcttcaacag ataaattcaa aagttcccac tcagacattt ttttcacttt ttcaggcagc
    94201 acttccttga cagctaaagg aatcgatttg atgcaacggg cgtaccataa tccttcaaga
    94261 ttagcaatag aaccatctgc tgcaatgtgt ccccatccgt ctgtcatatt gaataatgaa
    94321 gcaaaatcct gtcctacttc tgcttccatt tgcgaagttg ccatagaaga ttccaatgca
    94381 acattatttg ggttccacag catcgcatag ttgtaagcta ataaagcagg catcaatgtt
    94441 tcagcattca tttgtcccca gtaacggcct gctgaatgcc atgggatcga tcctgcgcgt
    94501 aatcgctgac tgacttcatc caagacctct atcatatggt cgcgggtggc tagataatct
    94561 ggagtgagct tatctccttc gctaattgca ggcatatctg aaggaatata attttctctc
    94621 catccaagat gttcatctac catcttgttc aacaacattt tataaactgg tccattttca
    94681 gctttgtcgc ctataaagac ggccttgata tccatatctt tcatttttct tccctccata
    94741 ttttgttggt caatgtcttg cagatacatg tgtttatctg taacacctct tcactatagc
    94801 gccaaaaatg agaatttttt ttttataaca tcaaatccac gtagattttt acaaacaaaa
    94861 ataaataaag tcggattttt ctgataattc aacgcaaaaa agcgaacaat ttttcaataa
    94921 atcagtcttc taaaatagat aacctaaaaa aagcgaacaa acaaataaaa tgactgtcct
    94981 tcattcacta aacatatttt tattttttta tattgttaaa aattcgcaat ttatttttta
    95041 atagaattat ctgttttcca aattttataa cataaaaaac cttttttaac ggcatttata
    95101 tgctttttca gaaattaact gatgatttca aaaagaaaac atgtcataat atttcccata
    95161 ttgtgcaaaa aaatacaagg cggaggctct actatgattg aagaatatat tgagaaaaat
    95221 attttaagac agctgttttt atgtgggcaa ttctatgtaa ataaagaagt caatctagaa
    95281 aagctctcca atctcctgca tgtttgcaaa accactttac tcaatgatat caataacata
    95341 aaaaaagaat ttgaagaaca gatcgcttat acacatcggg aaaaggaccg ttacacttta
    95401 tatttttcag aacatatacc tcgatgcaag atcatgcagc aattgtctca aaattcgttg
    95461 tttttaaaaa cttgtctgct ttatttggaa gaagatgaac ctgattatct tcaattaact
    95521 gaatgtgaat tcatctctgt cagcaaagct tattcattaa aaaaacaagt attagcttat
    95581 tttaatgact gcgggatcga aatcgaccgc tactcccctc gattcactga aatggaaaga
    95641 cgtctgctgc ttcttaatgt gtcgtatcgt ttaggcggtt ttaattcttg ggagctacct
    95701 gaatcgtttt ttgaacgtgc cgatcgtttc attgaatccg taacggaaaa tagtggcaga
    95761 ttttatgata aagaaaataa agaaatctta tcgattggtt ttgctatcag tttcctacgc
    95821 cagcaagtgt gtgctgtgac aatagattca aaatttatcg aagaaatcaa aaaacgtcct
    95881 atttacaatt atgtcgaatc agcatgggaa aacactgatt tccaaaccta ttataaaaaa
    95941 gaagaattcg cctttatttt gacactattc aatctttgta attatggttt ccattcttat
    96001 cagttgattg cggaagactt tcaacagcta caccaagtgt ttattgacaa tactcccgaa
    96061 ataaaagaac tagttgctac ctttgaatct cacttcaatc aagaattatt cggaaaccaa
    96121 ccgttcgaac gtgcgctgat tcatctgatg cgttcggctt gggataacta tcaattattc
    96181 atgccagaaa aattttatct tttaaatgag gaacagacaa atttatataa agaagtccag
    96241 acaatttttt ccagctggtc cagccagtta ccttatgatc tacggttgaa tcctaattgc
    96301 atgcgggctt ttgtgatcga attgagcgga attctccgtc tgacaaaaga acatctgact
    96361 atctatatcg tcacaaattc ggatgttcat tatctgattt atcgggaagc cttggaagct
    96421 gtaactactt tcgattttca agttgcacca acaatttatt caagtatatc tgatataaag
    96481 aagtatgcgc agcagtcctc aaaccgggta ttatgtgaac gtacattata tacaccagat
    96541 gcggtccaat atgaaaatat tattcctatt tcgatcaata cgatcgatcg agctatcatt
    96601 tcagctgtgc aaaacaaata aggggctgtg acaaaaatca tgtcacagcc tcttatttgt
    96661 tgaagatgcc catttctgta acaatctctt gatacacgtc aggctcacaa cctcacttat
    96721 tttggacatc tacgggtccg atctctttat ttaaaaaata agaaatgatg gttcggataa
    96781 ctaccaacgc cgctagttgg aaaatatcct gcaaggtagg tttgataatc gattcgatga
    96841 tcccagctga aacaagaatt tccaaactta gaagtatata gcctcccaac atctttttaa
    96901 tagcattgtt ctcgctgact cggtcgcttt gcacttttgt atggacaaat aaatatttca
    96961 aaaaatcctt gattgataga caaacacccc aaaccaataa acagatagca aagatatcaa
    97021 gtcccagtac aagtttttcg aaatatggaa gaagaaactg catcaactct gtcgtcatcc
    97081 tacctctcct cttctttgtt tttctttgtc ttctatttcc tgattcaaga aataagaaat
    97141 gactgttcga atgataataa taagtgcaag cttcaaaata tctgtccaag tcggcttgat
    97201 aactgactcg atgatatcag caacgactag tacttccaag cttaacaaaa tataacttgc
    97261 tagcagtttt cttgtatctg cattacgagt attacgttct gcatagtttt tcttgacatg
    97321 agaccaatca aaaagtttga atagaacaag aacgatcccg acaattaaga taccgataga
    97381 acaaatattt aaaatagcaa tgatccattc tagaaattca attaaatttg agcgaaacat
    97441 atacgctacc tactttcttt taatttgttc ctattctttt attgtaaaag aaagttacct
    97501 tgttcgtcta tttaaaagtt gttctaatga taacggttcg cttaaatttt tctttttcac
    97561 tctcccattt ttctccctcc atccataaat cgtggaagta tccaaaacaa cgtagcaagt
    97621 taaaataagg cttagtccgt catcagcttt tcaaagaagc actgtctcgg tgcttttttt
    97681 gtacccaaat ttctaaaaat agaaccatac acctcctcaa atcttttctt cttacctacc
    97741 ctatttttat ttacaggaaa atcagacact tcttcttttt tgtcaaaatt tcctttttct
    97801 tctcgtccta tcatttggca ttctaataaa aacgaactat ccttggatat agaaagagaa
    97861 aacaaggagg cgtttttcat gagtaaaaaa ttaatcaaag tcggcatcgg tttaggtttg
    97921 cttgcccttg gcgctgcata tctaggaaaa aagacaggac tattcgaaga tgacagtcat
    97981 ttatatgatg aattcgaatc aatctagcat cctatttagt tgaatcacta cggacatact
    98041 tggaagacat tggaggaatc acaatgagaa aaagtaaagc aataatgatt ggtgccggta
    98101 ttgccaatat ggcagcggct gtttatttga ttcaagaagg caaatggaaa ggggatcaga
    98161 tcacctttta ttcattggat gatcacggtt caaatgatgg tgcaccgacc gacactgtag
    98221 tggatgaata ttggaataaa aaccatccat tagaaaacca aaaaggctat attgctcgag
    98281 gcggtcgcat gcttaattac cgtacctatg tagatttgat ggatctgtta agtcgaatac
    98341 cttctgttac tgagccaggg atgactgctg aagaagatac gagagatttt gatgcaaaac
    98401 accgaacctt tgacaaagca cgtttgatgg aaggtggcaa aggaatcatt gatggcggaa
    98461 aactgggatt caataataaa gaccgtattc ttctgactaa actgattgct atgcctgatt
    98521 cagaagaaga aaaactagac aatatcacta tcgaagaata tttcaaagat gatccacact
    98581 tttttgaaac aaacttctgg tttatgtggg aaacaacatt tgctttcaga acacgtagtt
    98641 ctgctcaaga attgcgtcgc tatatgcatc aaatgattta tgaattcact caaatcgaac
    98701 atctagtggg cgtcaatcga acacgttaca atcaatacga aagtattatg cttcctttga
    98761 tcgagtactt gaaagaacaa ggatgcaaaa tcattttgaa ccgccgtgtc actgactggg
    98821 aattcaaaga aacaccgatg caagatgaaa tcactgtgac tggtttgaaa attaccaata
    98881 cactgactca agaagaagaa tacgttgtgg tcgatgaaga tacagcagtt attttcacta
    98941 atgggtccat tacagattca gctactttag gagattacga aacaccagct gtagaaaata
    99001 tggattatgg tgcagcttct agtctctgga aaaaagccag tgaacgtttc tacaacttgg
    99061 gaaatcctga caaattcttt gctgatcgag atgcaagcga atgggtcagc tttaccctga
    99121 cgacgaaaaa ccatttgttg ttgaatgaaa tcacccgtat cacgactcaa gaaccaggaa
    99181 atgccttgaa ttcatttatt tcaaccacac cgatcacgcc gttaggccaa aaagatgtca
    99241 atatgtctat cgtcgtgcat catcaaccgc attttacgtc tcagaaacca aatgaaacag
    99301 ttatttgggg ttatttcctt tatccaagac gacgtggcga atttgtggat aaacagtata
    99361 ttaaaatgaa tggaaaagaa atgctagaag aactgattgg acaactttca aaagtagatc
    99421 ctggaccagt gaatattcgt gaaaaagaaa cagaaatttt cgacagcgta ataaataata
    99481 tccctgtcta tatgccttat gcttccgcgt tgttcaataa tcgtgccaaa agcgatcgac
    99541 caaaagtcat tcctaaacat tcgaccaatc tggcctttac aggagaattt gtcgagcagc
    99601 cttatcagat gatctttact gaacaaagtg ctgtacgttc tggagaaatc gctgctttcc
    99661 attttgcggg tattcctatg tcccgtcttg tcaaaacacc gcgttacgac aaagatattc
    99721 ctactctagc tcgtgccgca aaaaaaatgt ttgaataatc aagaggttgt gaaaaagctg
    99781 ccctgcatca agtaataaga acaaccaggc taaaacagct tcttatgttt ttgatttggt
    99841 tg
//
LOCUS       DAFBSV010000003        79813 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.003, whole genome shotgun sequence.
ACCESSION   DAFBSV010000003 DAFBSV010000000
VERSION     DAFBSV010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 79813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79813
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.003"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            125..1168
                     /locus_tag="LLB18_000215"
     CDS             125..1168
                     /locus_tag="LLB18_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBK5243248.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(1230..1694)
                     /locus_tag="LLB18_000216"
     CDS             complement(1230..1694)
                     /locus_tag="LLB18_000216"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBK5243249.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            1940..2887
                     /locus_tag="LLB18_000217"
     CDS             1940..2887
                     /locus_tag="LLB18_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBK5243250.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(3098..5170)
                     /locus_tag="LLB18_000218"
     CDS             complement(3098..5170)
                     /locus_tag="LLB18_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBK5243251.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(5103..5480)
                     /locus_tag="LLB18_000219"
     CDS             complement(5103..5480)
                     /locus_tag="LLB18_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HBK5243252.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(5609..6187)
                     /locus_tag="LLB18_000220"
     CDS             complement(5609..6187)
                     /locus_tag="LLB18_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK5243253.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            6319..7611
                     /locus_tag="LLB18_000221"
     CDS             6319..7611
                     /locus_tag="LLB18_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBK5243254.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(7671..8789)
                     /locus_tag="LLB18_000222"
     CDS             complement(7671..8789)
                     /locus_tag="LLB18_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HBK5243255.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(8803..10224)
                     /gene="arcD"
                     /locus_tag="LLB18_000223"
     CDS             complement(8803..10224)
                     /gene="arcD"
                     /locus_tag="LLB18_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HBK5243256.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(10470..11591)
                     /gene="mnmA"
                     /locus_tag="LLB18_000224"
     CDS             complement(10470..11591)
                     /gene="mnmA"
                     /locus_tag="LLB18_000224"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBK5243257.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            11995..12594
                     /locus_tag="LLB18_000225"
     CDS             11995..12594
                     /locus_tag="LLB18_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBK5243258.1"
                     /translation="MNYFISDMHFFHEHLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(12732..14018)
                     /gene="efmA"
                     /locus_tag="LLB18_000226"
     CDS             complement(12732..14018)
                     /gene="efmA"
                     /locus_tag="LLB18_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HBK5243259.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(14289..14633)
                     /locus_tag="LLB18_000227"
     CDS             complement(14289..14633)
                     /locus_tag="LLB18_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HBK5243260.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(14770..15915)
                     /locus_tag="LLB18_000228"
     CDS             complement(14770..15915)
                     /locus_tag="LLB18_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBK5243261.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(16095..17069)
                     /locus_tag="LLB18_000229"
     CDS             complement(16095..17069)
                     /locus_tag="LLB18_000229"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBK5243262.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(17149..18024)
                     /locus_tag="LLB18_000230"
     CDS             complement(17149..18024)
                     /locus_tag="LLB18_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HBK5243263.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            18154..20061
                     /locus_tag="LLB18_000231"
     CDS             18154..20061
                     /locus_tag="LLB18_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HBK5243264.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(20602..23880)
                     /locus_tag="LLB18_000232"
     CDS             complement(20602..23880)
                     /locus_tag="LLB18_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HBK5243265.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(24151..24696)
                     /locus_tag="LLB18_000233"
     CDS             complement(24151..24696)
                     /locus_tag="LLB18_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBK5243266.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(24708..25400)
                     /locus_tag="LLB18_000234"
     CDS             complement(24708..25400)
                     /locus_tag="LLB18_000234"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBK5243267.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(25419..25703)
                     /locus_tag="LLB18_000235"
     CDS             complement(25419..25703)
                     /locus_tag="LLB18_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243268.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(25716..26279)
                     /locus_tag="LLB18_000236"
     CDS             complement(25716..26279)
                     /locus_tag="LLB18_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBK5243269.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            26507..27169
                     /locus_tag="LLB18_000237"
     CDS             26507..27169
                     /locus_tag="LLB18_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBK5243270.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            27293..28489
                     /locus_tag="LLB18_000238"
     CDS             27293..28489
                     /locus_tag="LLB18_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBK5243271.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(28590..29966)
                     /locus_tag="LLB18_000239"
     CDS             complement(28590..29966)
                     /locus_tag="LLB18_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK5243272.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(30003..30869)
                     /locus_tag="LLB18_000240"
     CDS             complement(30003..30869)
                     /locus_tag="LLB18_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HBK5243273.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(30958..31983)
                     /locus_tag="LLB18_000241"
     CDS             complement(30958..31983)
                     /locus_tag="LLB18_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBK5243274.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(32001..32675)
                     /locus_tag="LLB18_000242"
     CDS             complement(32001..32675)
                     /locus_tag="LLB18_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5243275.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(32859..33752)
                     /locus_tag="LLB18_000243"
     CDS             complement(32859..33752)
                     /locus_tag="LLB18_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBK5243276.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(33826..35523)
                     /locus_tag="LLB18_000244"
     CDS             complement(33826..35523)
                     /locus_tag="LLB18_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBK5243277.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(35516..36829)
                     /locus_tag="LLB18_000245"
     CDS             complement(35516..36829)
                     /locus_tag="LLB18_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBK5243278.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(36829..40347)
                     /locus_tag="LLB18_000246"
     CDS             complement(36829..40347)
                     /locus_tag="LLB18_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBK5243279.1"
                     /translation="MDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEK
                     KEISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMV
                     NFYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETL
                     YKDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDV
                     LFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGS
                     SNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAI
                     GRNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVS
                     PFGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYK
                     FSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSS
                     SIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFET
                     KMPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEY
                     TSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNI
                     NKLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDG
                     KYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRL
                     YDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTL
                     DGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQP
                     LHLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIID
                     GVLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPND
                     SSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTL
                     KVEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYIL
                     LAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(40640..41098)
                     /locus_tag="LLB18_000247"
     CDS             complement(40640..41098)
                     /locus_tag="LLB18_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBK5243280.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(41396..41914)
                     /locus_tag="LLB18_000248"
     CDS             complement(41396..41914)
                     /locus_tag="LLB18_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBK5243281.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(41916..42533)
                     /locus_tag="LLB18_000249"
     CDS             complement(41916..42533)
                     /locus_tag="LLB18_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBK5243282.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSFYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(42530..43384)
                     /locus_tag="LLB18_000250"
     CDS             complement(42530..43384)
                     /locus_tag="LLB18_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBK5243283.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(43381..44292)
                     /locus_tag="LLB18_000251"
     CDS             complement(43381..44292)
                     /locus_tag="LLB18_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK5243284.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(44333..45667)
                     /locus_tag="LLB18_000252"
     CDS             complement(44333..45667)
                     /locus_tag="LLB18_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK5243285.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            45875..46705
                     /locus_tag="LLB18_000253"
     CDS             45875..46705
                     /locus_tag="LLB18_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBK5243286.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(46949..47267)
                     /locus_tag="LLB18_000254"
                     /pseudo
     CDS             complement(46949..47267)
                     /locus_tag="LLB18_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(47389..47583)
                     /locus_tag="LLB18_000255"
     CDS             complement(47389..47583)
                     /locus_tag="LLB18_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243287.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(48088..48273)
                     /locus_tag="LLB18_000256"
     CDS             complement(48088..48273)
                     /locus_tag="LLB18_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243288.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(49123..49464)
                     /locus_tag="LLB18_000257"
     CDS             complement(49123..49464)
                     /locus_tag="LLB18_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBK5243289.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(49464..49694)
                     /locus_tag="LLB18_000258"
     CDS             complement(49464..49694)
                     /locus_tag="LLB18_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBK5243290.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            49981..50319
                     /locus_tag="LLB18_000259"
     CDS             49981..50319
                     /locus_tag="LLB18_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243291.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(50524..50763)
                     /locus_tag="LLB18_000260"
     CDS             complement(50524..50763)
                     /locus_tag="LLB18_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBK5243292.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(50739..51086)
                     /locus_tag="LLB18_000261"
     CDS             complement(50739..51086)
                     /locus_tag="LLB18_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBK5243293.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(51818..52399)
                     /locus_tag="LLB18_000262"
     CDS             complement(51818..52399)
                     /locus_tag="LLB18_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK5243294.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLVKERLLTSQKVL"
     gene            complement(52582..53208)
                     /locus_tag="LLB18_000263"
     CDS             complement(52582..53208)
                     /locus_tag="LLB18_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBK5243295.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(53230..54561)
                     /locus_tag="LLB18_000264"
     CDS             complement(53230..54561)
                     /locus_tag="LLB18_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HBK5243296.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(54716..55117)
                     /locus_tag="LLB18_000265"
     CDS             complement(54716..55117)
                     /locus_tag="LLB18_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBK5243297.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(55203..55409)
                     /locus_tag="LLB18_000266"
     CDS             complement(55203..55409)
                     /locus_tag="LLB18_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243298.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(55504..57006)
                     /locus_tag="LLB18_000267"
     CDS             complement(55504..57006)
                     /locus_tag="LLB18_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBK5243299.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(57024..57479)
                     /gene="argR"
                     /locus_tag="LLB18_000268"
     CDS             complement(57024..57479)
                     /gene="argR"
                     /locus_tag="LLB18_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBK5243300.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(57577..58194)
                     /locus_tag="LLB18_000269"
     CDS             complement(57577..58194)
                     /locus_tag="LLB18_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBK5243301.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            58415..59788
                     /locus_tag="LLB18_000270"
     CDS             58415..59788
                     /locus_tag="LLB18_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5243302.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            59863..60975
                     /locus_tag="LLB18_000271"
     CDS             59863..60975
                     /locus_tag="LLB18_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBK5243303.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(61047..62684)
                     /locus_tag="LLB18_000272"
     CDS             complement(61047..62684)
                     /locus_tag="LLB18_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HBK5243304.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAVVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(62852..63460)
                     /locus_tag="LLB18_000273"
     CDS             complement(62852..63460)
                     /locus_tag="LLB18_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBK5243305.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(63845..64996)
                     /gene="queG"
                     /locus_tag="LLB18_000274"
     CDS             complement(63845..64996)
                     /gene="queG"
                     /locus_tag="LLB18_000274"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBK5243306.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(65015..65767)
                     /locus_tag="LLB18_000275"
     CDS             complement(65015..65767)
                     /locus_tag="LLB18_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243307.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKNADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(65908..66858)
                     /locus_tag="LLB18_000276"
     CDS             complement(65908..66858)
                     /locus_tag="LLB18_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBK5243308.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(66859..67698)
                     /locus_tag="LLB18_000277"
     CDS             complement(66859..67698)
                     /locus_tag="LLB18_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBK5243309.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(67695..68441)
                     /locus_tag="LLB18_000278"
     CDS             complement(67695..68441)
                     /locus_tag="LLB18_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBK5243310.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            68679..70049
                     /locus_tag="LLB18_000279"
     CDS             68679..70049
                     /locus_tag="LLB18_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK5243311.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(70104..71000)
                     /locus_tag="LLB18_000280"
     CDS             complement(70104..71000)
                     /locus_tag="LLB18_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBK5243312.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(71114..71284)
                     /locus_tag="LLB18_000281"
     CDS             complement(71114..71284)
                     /locus_tag="LLB18_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243313.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(71281..71958)
                     /locus_tag="LLB18_000282"
     CDS             complement(71281..71958)
                     /locus_tag="LLB18_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBK5243314.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(72049..72954)
                     /locus_tag="LLB18_000283"
     CDS             complement(72049..72954)
                     /locus_tag="LLB18_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBK5243315.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     KNFKNIALDTLKKQLEKQTTVSWTT"
     gene            73129..74583
                     /locus_tag="LLB18_000284"
     CDS             73129..74583
                     /locus_tag="LLB18_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5243316.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVDPSH"
     gene            74599..75630
                     /locus_tag="LLB18_000285"
     CDS             74599..75630
                     /locus_tag="LLB18_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBK5243317.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGHFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            75637..76824
                     /locus_tag="LLB18_000286"
     CDS             75637..76824
                     /locus_tag="LLB18_000286"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HBK5243318.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            76980..78362
                     /locus_tag="LLB18_000287"
     CDS             76980..78362
                     /locus_tag="LLB18_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBK5243319.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            78334..78720
                     /locus_tag="LLB18_000288"
     CDS             78334..78720
                     /locus_tag="LLB18_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243320.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(78920..79588)
                     /locus_tag="LLB18_000289"
     CDS             complement(78920..79588)
                     /locus_tag="LLB18_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBK5243321.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
BASE COUNT        22854 a        16702 c        14265 g        25992 t
ORIGIN      
        1 tattcgaaac aagaggtcgt acaagacttt tgtcacgacc tcttgttctt ttgtcaaaat
       61 actggtttag tgctactatg ttcgagtatg cttttagtat ttattgacga aaggaaccga
      121 tcaaatgaaa tcattgtcac atccaataaa atctgtaaag gattcagcgg tccgcgaaat
      181 cttacccggt ttactgcttt cttttgccat cgctgccttc agcaggcttc ttgctattta
      241 tctgccacag ttaggtggag cgactattgc tattttattg ggtattttat taggaaatac
      301 tttttttaaa cagcctgttc tagcaatcgg cacaaaattt gctgaaagca aactattaga
      361 attctctgtt tttttactag gtgcaactgt cacagctcaa acgattgctc aaattggtgt
      421 aaaaggaatt gtttttgtgt tactgcaaat gtcagtcact atcatcggtg cttacttgat
      481 tggtaaaaaa ctgcaattca gcgatacttc ttctttgatg atggctggag gaaacgctgt
      541 ttgtggttct tctgctattg cttcaatcgc cccttccatc catgcgaaag aggaagaaaa
      601 aggacagatc atcacactag tcaatctact gggtactgtg atgatgttga ctctcccttt
      661 tcttggatta cagttgtttg gtggaaatct cattgaaaaa agtgcacttt tgggtggtac
      721 actccaatct gttggtcaag tagtcgctgg ggcaagctta cttgacaatt ctgttgtcga
      781 attcgccatg ctatttaaga ttctacgtat tatgatgctc gttgttgttg tctatctgtt
      841 tgaaaaattc atgcacaaga aacaaccagc tctgtttgaa acgccaactg atacgcagaa
      901 aaaacgaaaa ttaccgcttc cttggtatgt attagggttt gtgatctttt gtttggtcaa
      961 cagcttgttt tctttacctg tagttattga ccaatcggca cattttatca gcagctggtt
     1021 tgagatcact gctttagcgg caattggtct gcgtttagac tttgcaaaat tcatgaaaga
     1081 aggtacacgc ttcttatctt atggattagc tgtcgggctt ctccaaacag tgatggcttt
     1141 actatttatt tggctgatca aagtttagaa tgaacatgaa aaaacagttg tgattctcgc
     1201 atggaacaat gtccgaatca caactgtttt taattttgca gatatccttc taacaacaac
     1261 aattggcgtt tgatttcaac cccatctatt gcgtttccca tatatcctgt cagttttcca
     1321 ttttgcccga tcactcgatg acaaggaata acgattggca atggattggt tcgatttgcc
     1381 tgcccaatcg ctcgcacagc tttcggacta tcaacagcaa cggctacttc tttatacgtt
     1441 cggatttctc cataaggaat ggtcgacaaa gctttccaga cattttgctg aaaaggcgta
     1501 cctctcttta tagataaagg aacatcaaat tcttttcttt ttcccgcaaa atattcttca
     1561 aactgttctt gtgtgcgcgt taaaattcgc tgattcgctg attcgctttc tgaaattggc
     1621 tgaaaagata cagcagtcaa tccggattca tctgcatcta accataaaaa gccgataggt
     1681 gtgtgtattt tcattttgtt tgctcctagt caatagactg gaacttcctc ctttttctct
     1741 atccaaaact acttgccaac taataaaaat tgttcttaaa agtttgataa accgaggaaa
     1801 catggtaaac taaatacgtt agtttacaaa aagaatacct gttcttttac gtaaaatcaa
     1861 attttaaagg tgttatttaa ggtttattaa attttgaatg taaaccatat ataaacatac
     1921 gattgaaagg atagaaacga tgaaagtatc aattgttgtc ccatgtttta atgaagaaaa
     1981 aactgttcct cttttttttg atgaggttga aaaattcaaa ggtgcccatg agttcgaata
     2041 tttgtttatt gacgacggat caaaagacgg tacgttagca gcaatcaaga agctagcctc
     2101 agcttatcct tatgtccgct ttgtctcatt ttccagaaat tttgggaaag aagcggctct
     2161 gtacgctgga ttgcaagctt ctacaggaga tttagtgacc gtgatggatg ttgatctgca
     2221 agatccgccc gaactgcttc ctgagatgat caaccggatc actacttctg atatcgattg
     2281 tgtcggcacc cggcgttcga ctcgtgaagg cgagcctgcg atacgcagtt tctttgcgaa
     2341 aaaattctac cagttgatca ataaaatcag cgatacagaa atggtcgatg gcgctcgtga
     2401 tttccgcttg atgactcgtc aaatggtgga tgccgtccta gaattaacag aatacaaccg
     2461 attttcaaaa ggattattta gctgggtcgg atttaaaaca gaatatattt cttatgaaaa
     2521 ccgcgaacgt gtggctggcg aaacatcttg gtccttctgg aaattattca actactcgat
     2581 tgatggtatc gtgaacttct cggatgcacc gttaacgatt gcttcattta tcggcgcttt
     2641 gtcttgtgtc ggttctggta ttgcaatttt gttcattatt ttgcgggcat tgttgtttgg
     2701 tgatcctaca tcaggatggc cttccatggt ctcgatcttc ctgttcattg gtggaatcca
     2761 attgttatgt cttggaatca tcgggaaata tattgggaaa atcttcttag aaacgaaaca
     2821 gcgtcctgtt tatatcataa gagaaacaga aaaagtgaag ccaaatgaat tgaagcctca
     2881 ccaataatat acgtcaaatg aagtaaacat ttttttaaat gaaaaaggac tgtgacaaaa
     2941 gtcttgtcac agtccttttt tccgaataaa tggtgttcca gaagtagctt cttcggaaat
     3001 aagccgaaat ttcacaaaaa tttgagaagc aattttcgta aattccttct tatttcttga
     3061 agctgaccac ttctatcaca acctctttca tatcttatta cttcttcatt gctgctttta
     3121 gtgctgctgc taatgggctt tcttctggtt cttctgcttg tgcatatttt ttcagcaagc
     3181 gtcgttcttc atgtttggtc attttcttct tctgctcttt tttatcaagc aatttttctg
     3241 tcgttccatc gtatttacaa cggaaataag caccgttttt accttcgatg atttccattt
     3301 tccggtgaca ttgcgggcat cgatgattag agacttttgg atcttttctt ctgcggtagt
     3361 tgcaatctga attggtgcag acatagattt tgccgtcacg tgtgtttttc tcgcgcagat
     3421 tggccccaca ttctgggcat ttcttttggg taatcgagaa atcttgatat tcttgtttgc
     3481 ttgatttgat ctcattcacc aagcgttttg tttctttttc gattccattc aagaaggttc
     3541 ctgcttgttt ctttcctgca gcaatagctt caaggtcttt ttcccagctt tctgtcaaat
     3601 ctggtgttac taaagaggga tttaccaata ctaataattg cttaccttta ggagatactt
     3661 gcagtccttg aggggtacgt tccatcagtt cagatttgat tagtttctcg ataatctctg
     3721 cacgcgtagc tggggttccc agactgtatt tttccatttg accaagcaag cttgcttctg
     3781 acaatggttt aggcggtgca gatagttctt ttttgatggc gaaatcggga ttgattctca
     3841 ttcctttttc ccatttgact gtttccgtct cagtttcagt ttcgcctttc catcctgctt
     3901 ggacgacacg attttgccga aaaatgaatc gttctttacc aaattcaacc gtaacttttg
     3961 tttggctgac tttatggggt tgagcaaaca gtcctaaaaa acgagagaca atcatttgat
     4021 agatttttcg ctcttcatta cttaattttt cataacgtgc tctgttttca gttggcaaaa
     4081 gtgcatggtg atcggtcact ttactgtctt ggaatacttt tgtctgttgg acgatggctc
     4141 cgtttttcaa atactgcttg acctcaggag caaagtcgct gactgcttgc aatcgttctt
     4201 tcatcgtact tttcatgtca tttgtcagat atttgctgtc tgtacgcgga taagtaacga
     4261 tcttatgggt ctcatacaaa ctttgtacaa gacttaatgt tttctttgca gaatagccat
     4321 agcgttgatt ggcttctctt tggatctctg ttaaatcata aggcaatggc gcagattccg
     4381 tttttaattt ttcttggact tctgtgacag ttcctttgct tgtactgatc aattgaacaa
     4441 gtttttgtgc ttcttcttgt gtttttaaag caaattgatt tttttgaagc attttggctt
     4501 gttcttttcc agcttgcaac gtgatcgtga aatacgtttg tggacggaac tgctcgattt
     4561 tcttttcttg gtctctcact aatgctagtg tcggtgtctg cacacggcct gctgataaat
     4621 tatccgcgta cttcacagtt aaggctctgg tcacattcaa tcctaccagc cagtccgctt
     4681 ttgcccgggc aagagcagat tcatacaatg catcatattc tttcgcaggt cttagttgct
     4741 tgaatccagt tttgattgct ttatctgttt gagaagagat ccataaccgc ttcactggtt
     4801 tattgaaatg cacatactct aagatccagc gagcaacaag ttccccttct cttccggcat
     4861 ctgtcgcaat gactgcttct gagacatctt ttcgctgagc cagctgcttg attgctttta
     4921 attgatgtcc tgttttagga agtggtttga ttcctagttt tttagggatc attggcaacg
     4981 tgtccatttg ccagctctgc cattccttat tcagatcttc cggcattttc aatcctaata
     5041 aatgaccaag ggcccaagta acgatcacct tgggtccttc ataataattt ttgtgctttt
     5101 gattagcacc aagcaccttg cttaggtctt tcgcaacgct tggtttttcc gctagaatta
     5161 gttgtttcat aaaattcctt tctgctttct actgtgatgg gctgatgatt tttcaacaac
     5221 gcaagtccct tgtattgctg taaatcatcg tcacactctt cacaccagcg ctcatctccg
     5281 tcattccaaa aggcgctgag aaagttactt tttgcattga tatattcata attttgatgg
     5341 atttcgttcc attgtttttc gtacgcttgt cgtgcttctt cgaaagactc gaatgtttct
     5401 tcttcttcaa tatcttcttc ccagtcttca aaaaaccacc aaggctcatt gtccccgaac
     5461 atggtaatta cttgatacat actcgtgctc cttctttcag cttttctaga ctcatcttag
     5521 tcacttttca agaaagttgc aagaattttc tcttataaaa gggtcattta atgaacatct
     5581 taaaattgtt acaaatgaat ctgattgttt aaggcaaagt agcgataaag ttattgatca
     5641 tccaaaaata gctgtcttct ggatcgattg ttggttcttt tgtaaagtat cctaaaaaac
     5701 gtaaggaaag ataaccgtgg atcatactac gaagttccct gcttcgatga actttttctt
     5761 ctttcgttaa ttgaaaagcc tcaaatatct gcaaaatgat ctgattcgtt tcatggattc
     5821 catctaataa aacagcttca ttggtatgcg gtacactgat cagtaactca tacactgctt
     5881 gatttgaaaa agcaaaggat cgataagttt ctgcatagat ctgcagtgct tcctgaccac
     5941 tttttcccac aagagcccgt cgcagctggt cattaagttc ctgcagaagt ttcgctgtta
     6001 gcgctgtttt gacatcacga atatttttga aatggttata cagcgaggga gccttgatat
     6061 ccaagcgttt ggctaaatgc tgaaaggtta tttgctgaac atccatctct tctgctagtt
     6121 ctcgaaagca gtcgatgatt ttctcttgag acagatttct ttttttcatt tccatgtttc
     6181 ctctcataaa ataaatcctt cactctttca gtttaccacg aaaaagaaag agaaaaaaga
     6241 gactttcatt gataaactac atattgtagt ttataataaa gagctgtaga tgaaaatttt
     6301 cagaaagaag gagtctaatt ggctgcaaga ataaaggaaa aattatttag gaaaagagaa
     6361 acttgggaac aaaacttgtt tgtcttatgg tttggaacat ttatggctgg tatcggattt
     6421 agtttagtca tgccttttat gtcactttac atagatacgt taggtaatta tagtacgtca
     6481 caattgaact tttggagcgg attgactttt tcatctactt tcttggtgac tacgcttatc
     6541 tctccttggt ggggaaaatt agccgaccaa aaaggaagaa aattgatgct gttgcgtgct
     6601 tcattaggaa tggcaatcgt catttctttg atgggttgcg tgactagtgt gtatcaatta
     6661 gtcgcattgc gtctgcttca agggattttt tctggttata tcagtaatgc cactgccctt
     6721 gtcgcaactg ggacgccaaa agaaaaaagt ggtcaagttc ttggaacctt agcaactggt
     6781 tctgttacag gaacattact tggaccgctt cttggcggga tctctgcttc agcgtttggc
     6841 tatcgcccta cctttttcat tacagggatc atcttatttt tcgtcttctt gttgagtctg
     6901 tttttcgtcc atgaaaaatt tgtcccagtg aaaaaagaaa acatggtttc tgccaaacag
     6961 attttcaaag acttgaaata tccacacgtc gtcatcggta tgttcgtcac aacgatgatc
     7021 atccaagcat ccaacaattc cattagtcca atcatcagtc tgtacattcg ccaattgctg
     7081 catggacatg ggaatgttac gttgatcagc ggaatcattg cttcgatacc tgggattgcc
     7141 actttgatag ccgctccaag atttggtcgc ttaggtgaca agattgggag tgaaagaata
     7201 cttgcgattg gtttgggttt tgcgattctg gtttatatcc caatggcatt cgtcacgaat
     7261 gtttggcaat tagctgcctt acgttttttg attggtatct ctgatgcttg tctgctccct
     7321 gctgtccaag cattgatcac aaaatattcg cctcatcaag ctgctggacg gatcttcagt
     7381 tataaccaat ctttccaagc aactggtaac gtagtagggc ctatgatcgg ctccagtgtt
     7441 tccagtgcat ttggttatcg tggcgtcttt ctttcgactt ctcttcttgt tttggtcaac
     7501 ttcttgcttg tacgacacaa tacacaagag atccatcagc aagaaactgc agaagaaaaa
     7561 gcttcaggag tctccatagc ttcagggcac tctccttctc atagacaata agcgtaaatg
     7621 aaaaacactg cttgaacagt tgtcacagac tgtccttgca gtgtttttgt ttaggcctgt
     7681 tttttcaaga actcagataa gaggaataat cccttttcca aggtttcttt tttacaacag
     7741 taacctagtc gggcatgctt cggtaaatca aaggcacttc ctggtactaa tagtactcct
     7801 gtttcttcta ataaattgat acaaaatgtc tggtcatctt cttcgatggc taatttaatg
     7861 aaagaagtag agacgtaatt gggagcgaca agttcaactt tcggttcatt ggctacccat
     7921 tgttttaaaa tcacaaggtt ctctgtaatg atctttttgt ttcgcgccaa tattttttct
     7981 ttattcttca atgcatgtac agcaagatca tctgacagga ctccgccgca aatcatcgtg
     8041 tagtctcgat actttcgaaa aacttctgcc aactcaggtc cagtagctgt ccagccaata
     8101 cgaatacctg gaatggagta ggttttggat agggaattgg ttgctatacc tttttcatag
     8161 acatctacga tcgacaagaa ttcaccttta tccgttaaag gcgcatatac ttcatctatc
     8221 aatacatatg catctactgt acgagcaatt tctgcgattt tttctaaagt tttccgatct
     8281 agcaatgtgc ctgtaggatt gtttgcacta ttcaaacaga tgatttttgt ttcaggtttg
     8341 actaaggctt ctagctgttc taaatcaaac tgccaatctt cttcttcctt caaatgaaca
     8401 aagtcaacag cggcacctaa agatttgggg atgtcatata attgctgata agtaggaagc
     8461 atcgaaacaa catggtctcc tgcttccact aacgcgtata gagctaaaag attagcacca
     8521 gtcgctccat tcgtttgtaa gatgttttcc ggatcgacgg tttgataaag agaagcgact
     8581 tcttgtttga aaacatctga tccttcgatc cagccatagt ccaatggttc gtttttgcgt
     8641 ttttcgaaaa atttacttac gctagtccca tctaagccaa cgagttcgtc taatgtcaat
     8701 gcttcgatcg agctttgtgc aatatcatat accgctttct tttcccattt atttagccat
     8761 tcttctacac cgaaatttgc gattttcatg tttctttccc ccttatatct tgatccagcc
     8821 tacagcaagc aacccgattg aaagcagtgc ggctacacaa atcagcccaa tcattacttt
     8881 ttcttttccc gtaatttgat gtttggtttc acgacaagcg atccagtaga agcaaaaacc
     8941 aggaagatag gcaatactac ataaaaggac ataagaaaat cctgctaaaa tgatgcccat
     9001 caattcaaaa actacagcaa tcccaccgat cactacttgt tttttgattc cttcttttaa
     9061 agaaaactgg acttgataga tcccgacaag tagataacaa atcaaaattg ccgctgtaca
     9121 taaagaatag gcaaattgat aggcataatc agtaactaag aaagtcaata agaatagatt
     9181 agtcaagatt gcagtaacaa ctaacgaata agttggggca ttttttttat tcgtttttcc
     9241 ccaacctttc ggcaacagac cgtctcgagc catcaacatc gttgtttctg ctgggagcat
     9301 cgtccaagac aaccaagaac caatgatcga aataatcaag ccgatattga tcagcgctgc
     9361 tccccaattt cccacgattc cttttaaaat atttgccata gcaggttgtg aaatagttgc
     9421 taactcttct tgagataaga cgccgtatgg caagatcgaa gcaaggatat agataaacaa
     9481 taaacaaagc agaccaatga tcgatgcttg ctgggcttct gaacgtttct tcgcgcggtt
     9541 ggctaaaaca cttgcgcctt cgatccctac aaagacccac atcataacca tcaaacaacc
     9601 tttaatctgc aaccagatcg ttccttgctg ccctgttcca ttcactagat tatcagatac
     9661 gttaccccaa aaatcagcag tgaatatatt cactttaaat gcgataaata caaatattaa
     9721 aaataggaat aatggcacta atttacagat cgtcacgatt gtattgatga cgctcgctcc
     9781 ttcaactcca ttgtttacta ataaagtcag accccaaata aaaatacttg caaataaaat
     9841 agaaggaaca ttttgtccac ctttgaatat cgggaaaaat tctcccatgg cgctcatcag
     9901 catcgttgca aaagcaacat ttcccagcca cgcagacaac cagtaacccc aaccactgat
     9961 gaagccacct aatttaccaa atgaagcttc cgcgtaaccg aaaataccac catctagatc
    10021 tggacgcttt tctcctaaat gattcagcga taataccaaa gctaaaatac caatcccaac
    10081 gattatccat gaaaggatcg ctggccctgg agctgcagaa ctagccagat cacttgtgat
    10141 cccaaacaca ccgcttccga ttgacgaact gacaaccaga gcaaccagtc cccatttgct
    10201 aatacccgtc gatttctttt ccatttccat caccctcact tataaaattg aacaaatcac
    10261 ttgcaaaaga ttcccttcta ttttgcaact gctcttgctt aacaaaaagc aactttattc
    10321 atattattgg atattatgaa ctttttacac aagtatttca agtataaaat gaataaaaat
    10381 taattttatt gcaaaaaaac agctatgcta tccaaaagaa aaggtgtttc ttttgttagc
    10441 catagctgtt ttgattcatt taatatcgct taaacgtatt gtaaaacttt tgtttcttga
    10501 tatgcgtggt cgatcaaacc accacccaga cattccattc catcataaaa tacaactgct
    10561 tgtccaggag tgattgcacg tacaggttcg tcgaatacga cttctgcacg attatcatcc
    10621 aataagcgaa ctgtcacagg aacgtcttgc tgacgataac ggaatttcgc tgtacacttg
    10681 aattcttttg gcattggttc attcgtcgta aagtggattt cacttgcatc caagcttgtg
    10741 gcatacaatg caggatgatg gaacccttgc cccacatata atgtgtttgt cgctagatct
    10801 tttcctacaa caaaccaggg ttcttgcgaa tctcctccgc caccgatccc tagtccttga
    10861 cgttgaccaa tcgtataata catcaagcca gcatgttgtc ctttgacttc accatcaaga
    10921 gtgaccatat ttcctttttt tgctggcaga tagttgctca aaaattgttt gaagttcttt
    10981 tcaccaataa agcagattcc cgttgaatct tttttcttag cagtcgcaag gcctgcgcgt
    11041 tcagcaattg cccgtacttc tgatttttcc atgccgccta gagggaacat cgtttttgaa
    11101 agctgttctt gtgataattg gctaaggaag taagtttgat ctttattatt gtctactcca
    11161 cgaagcatgt ggaccacgcc gttttcatcg cgagtgactt gcgcataatg tccagtagct
    11221 acataatcgg cgccaagatc cattgcataa tccaagaatg ctttgaattt gatttctttg
    11281 ttgcacatca cgtctgggtt aggtgtacgt cctgcgcggt attcggctag gaaatattca
    11341 aatacacgat cccaatattc tttttcaaaa ttcacagagt aataaggaat cccgatttga
    11401 gcagctactt tcgctacatc cttataatct tccgtggccg tgcatacacc gttttcgtcc
    11461 gtgtcatccc aatttttcat gaatattccg atcacgtcgt atccttgttc ctttaacaaa
    11521 agtgctgtta cagatgagtc gacaccgccg ctcatcccta cgacaacgcg tgttttgctg
    11581 ttgtctgtca tgatatcacc atcatttcaa ttagattctg aaacatctac gagttgaagg
    11641 tcgcaacttt tcagtatttt acattatacg tcatatttct gaaaatttca tcccttaatt
    11701 atcaagtcgt aaaaatactg ttctactgga cctattcagt acacaaacat gatagtcaac
    11761 caaaaaatca ctcatctttt gagcattcga tataaaaaat tggcatactc ataaaaaggg
    11821 ccagcctttc ggcaataagg aataatttta taaattgtga aaaactattt ttcaaaattg
    11881 cttcttatcg cttaaagctg cacgtctcat ttacaacctt ttctttttag atgttatgag
    11941 ttgctcagat aagtgatttt gtttactcta agaaaaaagg gaggcaaaag atacatgaat
    12001 tactttatca gtgatatgca ctttttccat gaacacttat taggaaaaaa cgactttgct
    12061 ccgcggctct ttgcaaatgt ggatgaaatg aaccaacagt tgatcactag ctggaatgca
    12121 gtaataaaag aaaccgacca tgtttatcat ctaggcgacc ttgctatgca tccgcaatat
    12181 gaaaaagcaa atgcagaaat tttggaactg gtcactcaac tgcaaggaac aatccacttg
    12241 atcaaaggga accatgacag tcgcgctttt ttccgttatt tagaaaaaaa tgatcctagg
    12301 cttactgacg gaagtcccaa attttatttt tatgatgtag gtgccatcgt taaattcgac
    12361 catcaacaat attacttgac tcattatccg atgttgctcg ggcctaacga cactatccgc
    12421 aatcttcatg gacatatcca tcattacagc gtacctatcg agaacgatgt caatgtaggc
    12481 gtagacgcac cggaaagaga actcttaaag gaaaaactac catttggcac tccgttatct
    12541 gagcaacaaa tcaaagaaat ctatgaagca aagaggaagt acgataggtc gtgaaaaaac
    12601 tgccctatat caagtattaa acaaataaag ataattactc atatttttca tttgagtagg
    12661 cttattgcca caggaacatt aggatcagaa atggagttgt aacaagactt ctgtcacaac
    12721 tccattccat actattcgtc tttttgctca tggtgttctt ttaccagttt tttctgtaat
    12781 tctttatcat aatttcgggc agctgacgtt aaaaataaaa cgattccgca taataaaatc
    12841 ccgattccgg aaaacaagaa cattttttct acccctaaac gatcagctaa tggtcctgca
    12901 aataataatc caattggacc tgccaggttc atcaaagagt tgaagttccc taagacacga
    12961 cctaaaacat tcgattcata actctgctgg atcattgcca tcagcagtgt attgaaatat
    13021 ggcgttgcac aacctgctcc tgcattcaag ataagaaagt acaagaaccc ttgactatcg
    13081 tttggaacca atccgcttgc accgatcgtc aggcccataa tgatgtaggc tataataata
    13141 ggtttcattc ggtctttcca tgttcctata aaactgatca gtgcaccgcc taagagcatt
    13201 ccgactgcgt agactacttc cactgctccc gcctgtccaa cggaaccacc aaagtaatct
    13261 agcgtcatca atggatacag actgattgct ggcatgaaca acagcatcac aaatgcacca
    13321 ttgatcgtta tgtaccataa ccctttatta tccatcaatt gctgcagccc aaattttgca
    13381 tctttaaaaa tagtaagcgg aacttccaat atttcaggag aaacttttgg gatcttcaca
    13441 aaaatcaata agccgacacc aaaaactgcc cccaatacat ctaataaaat aaggtaattg
    13501 acaggaacga ctgaaaacaa agccgcacct agagctggcg caatgatgaa attcgctgat
    13561 tggaccattc ctaactgtcc attcgtcctt gttatgtgag aagatggaac gattgtcggc
    13621 ataatcgact ggatcgttgg catttggaat gtttgtgcga ccgaacgcat aaacaaagac
    13681 acaaaaacta gccaaatcgg gaaggattct gaaatcgttc cgactactgc taaaataagc
    13741 gcgaaaatcg ctacaataat atccgtgaca atcaaaagag cttttttatc ccagcgatcc
    13801 actagcggtc ctacaaatgg gcttagtaaa accatgggaa tcattcctag taaagtagca
    13861 aaactcaaaa ttgtcgccga accggtttct cttgtcaaat accagatgat cgcatattgg
    13921 acgaccatac tagtgattcc tgacaaaaac tgtcccgata aaaagaacaa ataatttctc
    13981 ttccaattcg ttaaaacgac cgactgttca ttttccataa acatccctct tttctttttc
    14041 attttgtata gcgtttgcac aacaatcatt atacgggatt cttttttcaa aaaatacctt
    14101 tttccctaaa taacaatcgt ttcaatttaa atttctttac ttagaaacaa taaatcagca
    14161 aaatattaaa aataacaaca tgtgttaaat ttaaaaataa aaaagacaac taatttgcgt
    14221 cgtccttaca aagttagtca tctaacaata ggccgtttca aaactagttg tctttttata
    14281 tccacagatc attcgacttt ttcgaataac ccacggctaa tcatcccatc catcagaaaa
    14341 taaaatttat cttggctcat tttctgtttt ggatctttga aaatattgac tgctttcaat
    14401 ccatttgctg tagtgatcga cattttcaat gtttgaatat cttttgatac agtgattttt
    14461 aatttgaatc cttctttgct ttgcggcgtg gcatctaatg gtcggatcaa ttgataattg
    14521 cctccgtttg tttctgtaaa tccattatcg cgcaatgtat atctttttgc atcaggatgc
    14581 aaacgatagc taattggtgc gcccagtacc gttgctgttg tttcaaatgc catgattttc
    14641 acctcgataa aattagtttc tctttattat aaaagtttat cctgattttt actaggtttt
    14701 tcagttaagt tccctaaaaa atgaaggcgt tctctcagac atctgttcat ataagaatga
    14761 cttcactagt tattttttga cagcacgaac taattgatca aggaaatact ggatgtcgtc
    14821 ttcggtattt cccaaaccaa agctgatacg gatggattct tttagtatcg gtgtatcttc
    14881 tccatacatt gcttctaata cgtgtgaagg ctcgatattt cctgctgtac aagctgaacc
    14941 agtagaaata gcgaccccat taagatcaag cttcatcagt agcaaatcat ttgcttcgcc
    15001 aattaagcga agattcaaca catgagggag tttattcgtt aaatcaccat ttacttgata
    15061 agggatttcg tttgcttcta atgtatcaag aatcaattgc tggaatcctt tatatttgtt
    15121 gttacgtgct tcacgttctt caggtgacag cagttcaact gcttttgcca taccccagat
    15181 ccctgctaaa ttttctgtac ctgcacgccg cttttcttcc tgctccccgc ctaaaagcaa
    15241 tgcagggata tttactccgt ctcgtttata taagaaaccg acgccttttg gcccattgat
    15301 tttatgagca gagatactta ataaatcgat tcctaattct tctggatgga tcgtttggtt
    15361 tccgtacgct tgtaccgcat ctgtatggaa ataagctgga tgatccgcta aaagttcacc
    15421 gatttctttg attggcatca aatttccgat ttcattgttc ccgtacatca cagagaccaa
    15481 gatcgtatct tctcgtaacg cttttttgac ctcttcgatc gacagattcc ctttttcatc
    15541 tacaggcaga tatgtaacgt caaacccctt tgtctctaaa tatttcatgg tattaagaac
    15601 agcaggatgt tcgatagctg tagtgattag atgtctgcct tctttttgac gcgagaacgc
    15661 tgtttctaag atagctgtat tatccccttc tgttccccca ctgttaaaga tgatctcgtg
    15721 aggttttgct tgcagactgt ctgcaatgat ttgtcttgct gtttccaatt tttcatgcgc
    15781 gtggcgacca aatccatgta tgcttgaagg atttccaaac gtgtcttgca tgattgccgt
    15841 catcgcttca attacttgtg gatgcatggg ggtagttgcc gcatgatcca gataaatagt
    15901 tttcacttca ttcatccctt ccaaattatt gctaggcaca ttctagcata aaatagcgaa
    15961 caaaccaaag aagagctcat ttttgtctag aggacgtttc atgggcatag aaaaaaggag
    16021 ctgtgacaaa agtcttgtcg cagctccttg aagctgctca cttctgtcac aacttctttc
    16081 cctctttttt ttgtttattc gaattctttt tcttccagac ggaataacgg actcatcggt
    16141 gtattttcat ggatgcgttt gaccgcttca cccattaatt ctgaacatgt aacgattgtt
    16201 aagttttctg gatgacgatt ttcttctgtg aaaacagaat cagtgataca aatatctttg
    16261 attggtgcat tgtctaaaat acttttcgca tgatcggaca ataatccatg tgacgcacag
    16321 gcatatactt cttttgcgcc gttttctttt aatacatttg ctgctcgtgc aagcgttgct
    16381 cctgtgttca agatatcatc taccatgata catgtctttc cttgaacatc accgatcaca
    16441 taaccaccct cagttgaagc atcatctgca tgatctacga tggctaatgt gctgttcaaa
    16501 tattctgaaa gactacgtgc acgctgaaca ccgctgtttt ttggcgaaac aactacgatg
    16561 tcatctcccg tcagacctaa ttgacggtaa taatgagcaa acaacggcat cgtaaataaa
    16621 ttatctacag gaatatcaaa gaatccttgt acttgaaccg tgtgcagatc taaagtcagt
    16681 actcgagttg cccctgcttc ttcgatcaag ttagcgatca atttcgcagt gatcggttca
    16741 tgaggtttcg ccgtgcggtc ttgcctagca tacccatagt aaggcaatac gacattgatc
    16801 gttttcgcac ttgctcgctt cattgcatcg atcatgatca gtagttccat atagtaatca
    16861 ttgacaggtg cattcgttga ttgaacgata tacacatgat cccctcgaat actttcttcg
    16921 atattgatgg aaatctcgcc atcactaaat tgcttcacga cgcttttacc taattctgtt
    16981 ccgaacactt tcgcgatttt ttcagctaat ggacggttgc cattcaaact aaaaatcttc
    17041 aacgtgtcat cctgatactt attactcatg tagtcctccc caaaacttct ctattcttcg
    17101 atagtttaac atatttttcc aagattttct gttaatttca gcaaattctt aaggaagtga
    17161 aactgttccg ttactccaac tggcaggaat gactttatga taatcgcccc agttgtcgtg
    17221 tactttgtaa taacgttctc ctgtttcagt ttcaaaataa gcgtacgctg tcacccaatg
    17281 attgccatat gtactgccaa gtactttcaa aataccaatc atcacaggtt tgccttcacg
    17341 tatacgtttt gtagctcgct gccatgaacc tagaagagtt gctcgtgcac gctcatgatt
    17401 gccattcttc tttaaaaaac tagaaatccc tgtactaacc tgaaaaggaa tcgtaggaag
    17461 tcctagtggt tggatctggc tacgcaatgc cttcgtcaaa accaacgaat cagccgtatt
    17521 tttcttgcga atctcatttg gaagcatcca ccccttacga tagtcttgat aataggcaag
    17581 gagaactgct gccgcgtaag taccacaaag atagcctgag ggggtagccc atttcttata
    17641 cctcaaaaaa cgttcttctg gcaatcccac ccagcaattt gcgagttcct ttcctgacct
    17701 tttttcttcg atcaaaacgg gaatatcttc ttttctgttg atccatctag ataactcgat
    17761 tggctcttca ttgatcagct tccatttttt acaagaaaga ccctcttgat aagtatattt
    17821 tgctggagaa tattctaccg gatgtcctga ttgatcgata atcacataac tttgatcttc
    17881 aaaaaccaga gctaaaaaaa gcaatttact ttttcttgac tgcagctgct gagtgctggc
    17941 taatttttta atttttttat ctactttgaa atataaaggt ttatccacta cttgattcag
    18001 ttgggatcgc ctcctttttt tcattataag tgaaggattg aaaaaaacaa atcagtttga
    18061 ttgttcgaat tttcaatttt ttatgttcta tttgttaatt ccttcatttt gtaagataat
    18121 gggcacacga aacaaaaaag gagcgatcga tgaatgaaca aagaacgatt gaaacaagat
    18181 ttctatgaag cagtcaatga agaatggcaa aaaacagcaa aaatccctgc agataaacca
    18241 gctacaggcg gtttccaaga tttagttgac gggatcgacc aacttttgat gggagaaaca
    18301 gacgatctgc ttgcccatcc agaaaaagtg tcttcagaaa aaatgaaaca tttccttgca
    18361 tattatcaac tggcaaacga ttatgaccga agaaatgagt tgcatgctca accgcttcaa
    18421 cctataatcg aaaaagttga atcattgcag tctttcgacg aattgaataa gcaatttcca
    18481 gaatggctgt tggatacatt accattgcca tttaatctgg atgtagatgc agatatgaag
    18541 aatgcgcaaa cgaacgcctt ctttgcttat ccgccttctt tattccttcc agataagacg
    18601 tattatgcat cagaccatcc caacggtgca caactaatag gcgttttctt tgatatggct
    18661 gttcagttat tagagcttgc cggcaaagaa aaaagtcagg cagaagcaat cacggaacaa
    18721 gcagtgcaat ttgataaatt gattgctcct catgtaaaaa gtgcagaaga aaacgcagat
    18781 tacagcaaaa tgtataatcc gcaatctttt gatacattta ttaaatacac agataaactg
    18841 gacttgaaaa aacttgtcac gggtttgatt gggacaactc cagataaagt gatcgtaact
    18901 gatccagtgt acttcgatca tttgaatgac atcctgacag aagctcattt tccgttattc
    18961 aaaagctgga tgatcattaa aacagtacgt tctcttagtg gttatctatc agaagaattc
    19021 cgccaagtca gcggaatcta ttctcgcgta ttgtctggaa cagacgaagc aatgcctcag
    19081 aaaaaagcag cgtattacct tgcctctgga caattcgatc aagtagttgg cgattactac
    19141 ggaaaaaaat attttggcga agctgctaaa aaagacgtag aacaaatggt gaaaaaaatg
    19201 atcgccgttt ataaaaaacg tctagaagaa aatgactggc ttggggatgc aacaaaagaa
    19261 aaagccgtca taaaattaaa taacttaggt atccaagtag gctaccccga taagatccca
    19321 gcattattcg accagttcaa aacagtacct gcagatcagg gtggtacttt gctttcaaat
    19381 actcttgttt tcagcaaact cacattaaaa gatcgtttca gcaaatggaa caaaccagtg
    19441 gatcgttcag aatgggaaat gagtgctgac acggtcaatg cttattatca tccatttcgg
    19501 aatgtgatcg tctttccggc agcgatcctt caagcaccat tttacagtct agaacaatca
    19561 agctctgcta attatggtgg aatcggagct gttatcgctc atgagatttc ccatgcattt
    19621 gataataacg gcgctttatt tgacgaatat ggcaacttga acaactggtg gacagaagaa
    19681 gatcttacac aatttcaaaa caaagcacaa gcaatgatcg aagaattcga tggtctgcct
    19741 tttgctgacg gaaaagtaaa cggaaaatta accgtttcgg aaaatattgc tgatgcaggc
    19801 ggtctaagct gtgcattgga agcagcaaaa acggaatcag atctttctat cgaggaattc
    19861 tttgtcaatt gggcaacgat ttggcgtaca aaagcaaaaa aagaatacca acaactttta
    19921 ctgcaaatcg atgtccatgc ccctgctaaa ctccgagcaa acgtgcaacc aaaaaacctt
    19981 gacgaattct atgaaacatt tggtatcacg gaacaagacg ctatgtatct agcgccagaa
    20041 aaaagagtgc gaatctggta agaggttgtg ccagaagtgg tcagcttcaa gaaataagaa
    20101 ggaatttggg aaaatcgctt ctcaaatttt tgtgacattt cggcttattt ttcgaagaag
    20161 ttacttctgg aataccatgt attagaggtt gtgaaaaagc tgcttagttt caagtagtaa
    20221 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttgactta ctaccgagaa
    20281 actggctttt gaacaccgtt tatcgagagg ttgtgaaatc agcgtcctga cctgagtatt
    20341 agagaaaaaa acggaaaaat agttcctcat attttgccgt ttgttgagct aataccgagg
    20401 gtcagctgat tgaacaccgt ttagtggaga gattgtgaaa aagctgtcct gcatcaagta
    20461 ataagaacag ccaatcaaaa gcagcaagga gaacctcatc tataaaaaga tagaaggaag
    20521 tgagacatct attggtctca tttccttcta tttttacttt cctcagtcaa ttgttttaca
    20581 tcataaaagg agaaattcca cttatttttt tcgctgtttc atgacataaa caactacacc
    20641 gattaacaaa attcctccag ctaatgctag caacgggtta ttaaattctc ccgtttttgg
    20701 gagtccttga gtgccatttt tttcactttc ttttgctgtc ctatccggat gagaaggttt
    20761 tccatttggt tttccatttg gtgattcatt tcctggattt tctctttctg gtttgtcatt
    20821 tcccgggggc acatcggcag tttctcgcac agtgatcgct ttttgctggg taacagattc
    20881 tgtatgagca gaccattttt ccccatcaaa tatttccgaa cgataagtga cttctagcgt
    20941 atattctcct tttgaaggtg ctgaaaaaat agcggtatga ttagaaaatt gagcacttga
    21001 ctgtgtttca acgatttgga tcttttctgg gaaataacgc atatcttcaa agacaggcgt
    21061 tccttgattt ggtgtgaaag ttgacacaaa aactgtaaaa ggcttcagtt caatgatatt
    21121 tccttctgca ttctccgcca caccatttgc ttcttgtata ataatcggat tattttgttc
    21181 atttggtttt gtctgatttg gttcttgtac gattgcatac tctggatatt ccgaagacgg
    21241 tgaggtttct ccgtcaaaaa tagcacctac agataatgga agaccatcca ctctttcctt
    21301 ttctgtttga cgattccccg gtttaatctg catcagtcca tgaacatgga tacttccatt
    21361 ttcatagcgc gtaacaggct gctgaccttc tttcgaacat gtatttagag actcgatcca
    21421 atcttttgat atggtatgtc caagagtatt ttctgattgt ttctctcgtt cattccaata
    21481 gtagttcaac gagtggtaga tttgatcttc gttttgattc aatgggcgga tctgctctct
    21541 catctcaaga ttctctgttc ggaaagataa gataccagaa gcatggtagt ctgtgtttcc
    21601 tgctgaagag gtataaagag ccacattata tgaaccgtta ttaaaacttg tactgctatt
    21661 gacgataata tctgttccgc tattggaatc gattcctttc gcaagatttt cgaaagacaa
    21721 actattgatc aattcatgag ggcccgttaa agaagaaccg cccattttga atccattacc
    21781 gttaccttct ccctcaattc ctggtaccca gccgtttcga taagcaactg agtttttgat
    21841 gattactttt ccgatcgaac ctgtttcatt tttagcaaaa aggtcccaac cgtcatctgc
    21901 attatgatac gcgatacaac cgtcaaatac atttccttct cctattgtca gtttggccgc
    21961 aaatccatcg gcatcttcaa atcctggatc ggcattttca aaagatgtac agttcttgac
    22021 taagttatgc gcgggccatg cttcgaaagg atcatttgag ctaccgctga tttggattcc
    22081 tgtatttcca ttccgataag catgaatctc ttcgatcaaa ttatgatttc cagaaatctg
    22141 taatcctttt tgcatagctg cactatttgt aatgtcaaac cctcgtaaac cccagtagtg
    22201 actgaacagt gtcatcccat ttccagttcc tttaaaatca agtacaggac gcttgttttc
    22261 tggatttttc tctgcaatca actgaatcgg gttttctctt gtcccgttaa cgccttttgg
    22321 aatcgtcaat cctctttcga aggaataagt tccaggcgcc atgacgattg tctgcccagc
    22381 atatgcgtat ctcaatgctt gtgtcagaga taatggattt tgtctgcttc cgtttcctgc
    22441 atctgaccct tctggtgtta cataaactgt cgaatattta ggtttacggt agtccactgt
    22501 atgaagaatc tcttttgttt cataactagt catctctacg tattcttctg gcggatagtt
    22561 tttatctggc gtaaaactga aagtaaattc gttcgttcct tccatcagtt ttgtctgata
    22621 atcaaattcc cgattcgcag tgatagccaa gttttttgcg ttcttaagca cctctcctgt
    22681 tgctttattt ttaattgtca ataatccgtc agcatttgct ctaaaggaca tagtatgatc
    22741 ttggtttcct gaatgattac tagaggtcac agtgtaaatc ggatcaatca agcgagtagg
    22801 tctttcttgc ccaggaggat ctgtcgcagg atctgagtaa gcaacttcga ttccttctac
    22861 cttgatcgtc atattccttg ctgcagcaaa tcctgcataa ataaccgatt catctgaagc
    22921 gtataatttt tcccagtcat acatgatgtc agaagccatt tcttctcctg tttcaggatc
    22981 gtaataatat gcctctaaac cagtattcgt ttttttcatc tctacgtcca gtttagtaat
    23041 cgagttcgtg gccggaaaca gattcccatg accgtttccg aatatattat aagaacctgt
    23101 ttctttttcc aagaaccctg ctgaagtctc taaaggtgtt gtttccactg agacactccc
    23161 aggagctggc gcagcttgcg gatcttcaga tgatattcct gtgattgccc gtgtccccaa
    23221 tccaagtcgc atcgtatatt tgctgccgct cgtgttgacc acttcttgtc tatccgagtc
    23281 ccagacatat tcgatccgac tgcctagtat ggcaaatgaa tttgaataaa atgcctgccc
    23341 aaacaaatga ttttttggta ctgcgtctct taccattaaa gcaaatcctt cttgggcatt
    23401 cgtataggtc caagattcta tttcgatcgt cgcccgcatc ctaaagttga tgtctttggg
    23461 gattgcttga taataatagg tcattccatc tgatccgctt gactggaatt ttccgccgtt
    23521 attcgtggaa gagagccgca cgccgtcttc taatggttca atggcatacc tactagcact
    23581 tgtgctttct ccgaaaacaa cccctttcca ctcttcattt gcttcttcag attgcttttt
    23641 tgtcttttca ttttctgatt ctttcatcat aggatcattt ccttcttccg tatccatatc
    23701 ttcactagtt cttggtattt cctccattgt tgacatccct tcaatgttca cgtgtgcatt
    23761 ttcttcgttc acagactgtt gttcgttagc agcaacttca acgacagaaa ttaaaaccgg
    23821 ggtactgagc ataaggagat tcatcattag cgcactgtat tttatacgtt tttttaacaa
    23881 gtgtattcct cccgtaacaa attagaaagc gtttacttaa agtattacct aatttatttt
    23941 tactgtcaat aaaaaacaaa attataataa gtgtatttta taaaaagaaa aaatataact
    24001 taagttgttg ataataaaga gatttattaa cgtaaaaaga ataagttttt ttaaaataac
    24061 gtataaaaaa gagcataaaa caaagtcgtt tgttttatgc tcttctttta ttattttgtg
    24121 ctttttattt tatcaaatca ctttgttttt ttataaaatt tctgcgccta gtgtggactc
    24181 aaaatgtctc aatgcccatt catgtccaac gggatcgaaa cttgccacgg catctttgaa
    24241 aatatggagt ttgtatccta gattatacgc atcgactgct gtatgcaaca cacagatatc
    24301 tgtacatacg ccggtcaaat aaatatctgt gatctggcgt tctcgcaaac ggatgtctag
    24361 atctgttcca ctaaaagcgg aataatgccg tttgtctatc caataaacat tttcctcttg
    24421 ctcatagtct tggtataaac tttttaaaga gccgtacaat tcccgtccac ccgttcctat
    24481 cacattatgc ggaggaaata agcggttctc cggatgaaag gaatcttttg gatcatgcgc
    24541 atcaatggca aaaacgacaa aatccttttg atcaataaac ttctttgtat gagcagtcag
    24601 ctttttttca attacttgtc ctgctgtccc agtagtcagc tttccatcct ctgcaacaaa
    24661 atcatatgtg tagtcaatcg agatcaatgc gttcatctta gtcctcctta tacgagatgt
    24721 ttgacaaatt cgatcaccat ttctgctgat cgtttgcctg cgtcttcgat aaattcgtca
    24781 aagctttgtg tcgccgagtg atctgctgtg tcgctcattg cacgtacgat caaaaatggg
    24841 atattgaact gacgagctgt ttgtccaaca gcggctcctt ccatttcgca agctaatgct
    24901 tcagggaaat tcgttaagat ttctttgatt ttatctggcg agtcgacaaa tgtatcacct
    24961 gtaacgatca atccttcttt tgcgttcaaa ttcgttgctt ttgctgcttt aaccatttca
    25021 ctgcgcaaat atgtgcttgc ttcataatat agaggcattc ctggtaattg tcctgggttg
    25081 tagccaaatc ctgttgcatc tgcatcaaaa taagctactt tgtctgatat aacgatgtca
    25141 cctacttgta agccttcacc gattccgcca gctgaacctg tattgatcac catgttcacg
    25201 ccgtattgtt ggatcaacag acttgtggta atagatgcta agacttttcc tataccggaa
    25261 cgtacgacga tcacttcgtg gttacctaat gaacctgaaa taaataaagc gcctgcgcgt
    25321 tcccatgata atggttcgct taggttctct ctcaaaattt ttacttcttc ttccattgcg
    25381 ccgataatac cgattttcat ctttttaatt ccttctttct atataaatgc gattgctaaa
    25441 aaaaccacac ataacattag gataacaata ataagagatt tcatcaaaaa agagttccat
    25501 ttggtcgtct tttcccgttc gctgatcctt gttttcgtga ttggtttatt ctttttgctt
    25561 tctttacgat aaaagctggc aatctttttt tcttcttgct gataagctgt ttctgctttt
    25621 cgctgttttt ttaatgactc gcttgcttgt gcttgttgtc gcttgcgaag ttcgcttcgc
    25681 gtaataagcg gtcctttggc cataagccga tccctctact ttcctttggt caatagttcc
    25741 cagtattgaa tcgcataaat cgtctttgca tcacaaatca actgatcttt catcgcttgt
    25801 tgcgcctctt caagagttag atgatacaac tccagtactt cgtcttcatc ttgtgctaaa
    25861 ggattctcga ccttctctac cccttgtgca tgataaatat gaaggacttc atttgcaaaa
    25921 cctggtgaaa gatacatcga agtaagatgg ctcagcgact tcgcacgata gccagtttct
    25981 tcttctaatt ctctagctgc tgtcatttcg ggattttgtc cttctcctgg atcgattttt
    26041 ccagctggaa tctccaaaat cactttttct aaaggttttc gaaattgttt gacaagaagc
    26101 agacgatctt gttcgtcaaa agcaatgatc ccgacaccgc caggatgaaa taccagttct
    26161 ctcttcgaag ttcctccatc tggcaaacga acttcgtcta cagcaacatc aataattttt
    26221 ccgctataga tttctttgcg actgattgtt ttttcttcaa attgctcatt gttcagcata
    26281 tcttctcctg ctttctttgt aatcataact gctttttttt catttttcaa tttttctcaa
    26341 aaactcctta ttagtttacc atagataaac cttagatttt ctctaaatat agaaaatcct
    26401 tctttagtcc gatactcttt atagtagtcc gtatgctaaa ataagtatgt aatcgaataa
    26461 cgaaaagaat tcaatactca acgataaatg acatggaggg tttattatga taaaacgaaa
    26521 ttggccgtgg cttctagcat tggtcttgct atttctcttt gtccgaaaca atagtttttc
    26581 ttttgttcta ggacttttat tgataggtgt agttttagtt ttgtggggac tctttggttc
    26641 gcgcaggaaa aagggaaaac aagaagaaat tcctgcactg actgacgaac ttgaaactca
    26701 ctatgaaaaa agcggtatga cagcgaatga aatttcattt tttcgacaaa caatgaatca
    26761 aacaaaaaat gagatcaatc aattgcaaat gaatatgcag cagacagcca aacttaaagc
    26821 aatcgatctc cgccatgatc cagtcaaagc agcgaaagct ttattcaaag aattggtgaa
    26881 agaaccaaac cgactgcatg aagcaagtca gtttctttat acgcatctgc cgaatctagt
    26941 tgatttgaca aataagtata atgagatcaa tgaccatgag atcaaaaaca aacagaccta
    27001 tgaaaaacta gaagaaagcg cgcagatcat cgaccagctg tcagctttaa tcgcacaaga
    27061 ttatcaaaaa ttcgttgctg aggatctaga tgatatcgac gtagagatat ctgttgcgaa
    27121 acagagctta aagcgtgata ataaatatga accagaacaa aaggattaac tcttttgttc
    27181 ataaaagaag actcggaaca ttcagatgat gtctggctgt ttcgagtact ttttctaaag
    27241 tagagacatt catgtaagaa tcgagaacag attcaacaag gaggaatttt ttatggatca
    27301 taaaccgact gaaacaaaag atgttacacc agttaacgat acacttgaag atttattgaa
    27361 caacccgttt tcaactccaa cagatacgct gaccacttca caacaagcgg agattgatca
    27421 gctccaagag caacagacag ctgctcgttt aattgacaaa ctaccggcgg aacgccaaga
    27481 acaagctaaa cagctagcag caaaaatcga tgctaatgat gcacagtctg tcatcagcta
    27541 cggatcggct gcccaagcaa aattaagtga attctcacaa tcgatgttga atcatgtgca
    27601 agcacaagat attggtcctg taggagattc cttaactgaa ctgatgtatc gtctccaaga
    27661 agccaatcct gacgaactgc gtgccggaga agggaacatc ttccagcgtg tcttcgggaa
    27721 ggtcaaacaa tcgatctatg aagtgacagc aaaatatcaa aagattggtg cacaaattga
    27781 caagatttca gtgaaattag ataaagaaaa agacggtctg ctaaaagata atctgatgtt
    27841 agaacagctt taccagaaaa acaaagacta ctttgatgca ctgaatattt atatcgctgc
    27901 tggagaattg aaaatggaag aacttcaaac aacgatcatt ccagaagcga tgaaaagagc
    27961 agaagaaact ggcgatcaga tggatgttca gattgccaat gattacacgc aattcctaga
    28021 tcgtctggat aaacgtacgc atgatcttcg cttagctaga cagatcacga tccagcaagc
    28081 accacaaatc cgtttgatcc aaaacacaaa tcaggccttg gctgaaaaga tccaagcatc
    28141 tatcgctaca gccattccgc tgtggaaaaa ccaagtcgtg atcgcattga ccttgcttcg
    28201 tcaaaaagat gcagtaactg ctcaacgcca agtctctgaa acaacaaacg acttattgaa
    28261 gaaaaattca gaaatgctga aaatctcagc catcgaaaca gcgaaagaaa atgaacgtgg
    28321 aatcgtggat atcgagaccc ttcaaaccac tcaaaatgat ttgatcgaaa caatccaaga
    28381 gacattgcgt atccaaaaag aaggaaaaga aaaacgtcgt catgcagaag tagagcttgg
    28441 acacatggaa gaagatctga aacaaaaact gttggattta acccaataga tcacctttcg
    28501 cttgttacta aaacaaacgc ccaacaacag tttattacaa ctgttgatgg gcgtttttct
    28561 tatctttctt ctaacttctc cattggagtc tatttctcat tcatcttgct gtgtccatag
    28621 ccatagccaa aataaatgat cagtccaata accattacga taccgaacac gatccatgtc
    28681 acagtttgca gacgaagcat caatacaata caagtcaaga tggagacgat tggcaatagc
    28741 ggaacgaatg gcactttgaa ttctccagct tttggtttgc caaacatttt tctcaacttc
    28801 agtaagccta gactaacaag catcaaatag gcgagcgcca tgatattcgt tagttccgct
    28861 aatacattca atgggaaaaa tccggcaaag aatacagctg ccacaccagc ggcataagtc
    28921 gcttttttcg gtgtacgatg cttttgatcg atttctgtca taaacttagg aagtaagcca
    28981 tccttgctga cagcaaacag taaacgagca agtgaataca tcatcgagat cgttaccgtc
    29041 agtagcgtta aaattgcccc tacagcgatc accgcgccca ctgttccatg tcctacatac
    29101 ctcattgcaa aagccactgg gtcattgact cctagttcag tatacggaac gattcctgtc
    29161 aagatcagcg tcacgatgat gtaaaggaca gtagcaatca gtatcgaacc aatgattcct
    29221 cttggcacat ctttttgcgg gtttttgact tcctcggctg ccattgcaac ggcatcaaat
    29281 cccaagaaag caaaaaacac aagagctgca ccatctagca caccggaaaa accaaaaggc
    29341 atgaatggct gccagttatc aggtttaacg aaaaatattc ctacaatgat aaacaacgcg
    29401 atgataccaa atttgacata taccatggca ttattcaaac gtaatgcttt cttggcttca
    29461 agcgacacga tgtaagtgac gaatatcact acgagcaccg caatcaagtc aatgtatgta
    29521 ccattttccg gattgtaccc gccagttaat gcttgtggaa gttcggcccc taaacttttc
    29581 aaaaaacctt gcatatagcc agaccatccg gaagcaacag aggaaaccgc tagtaaaaat
    29641 tccccgatca acaaccaccc tgtcagccag gcagcaaatt caccaaatac aacatacaga
    29701 taggcatatg gcccaccaat cactggcact cgcgaagcaa attctgcgaa acttagtcca
    29761 gacaaaatga caacgattgc agctaagaca aatgaaagtg acagtgctgg accagcattt
    29821 tgattggccg caacccctgt caccacaaat attcccgtac cgatgatcgc accaattcca
    29881 agcatgatca aatcagacgt ttttagttct tttttcatct cactcgtatg attgagattg
    29941 atctctttct tacgaaacaa atccattgaa gttcctcccc attttaggtt ggaaaacagc
    30001 gattaaactg ttttcatata ccctaaaagg ataccaccta aaatgactaa aaggcaacca
    30061 acaataacat aaatgagctc ttttttcgtt tttctttcgc caaggatgaa aatcccacct
    30121 aaagtagaga taatgatccc catttgtgaa agtgagaagc caacagctaa accaagtgat
    30181 ttgactgtta gaagcatgca gatgtttcct aagccccata ataatccaca gatcatgttt
    30241 ttccacacaa actgatcgac tttaacttta cggaaagcaa agaagcttgc gcctaagatc
    30301 attccgatac tttgaggtaa gataattgac atcgcatcca aattcgccca gttgacgatg
    30361 atggtatata caccataacc aatcgtagag aagatcaatg ctctaaaacc cttaccaaaa
    30421 tcaagcattt tattatctgt atctattttt ccttcgtcat cttgtcgggc agtcaaatac
    30481 gcaccgctta caagaagagc taaagcaata ataccgtata cataatcttt cgtttgtgtc
    30541 cattcatgga agaaaacggc tcccgcaatc gtattcaaaa ttaattgaaa accagtagac
    30601 aatggtagcc ctacagaaac acccatgtac ttcattccat ggaactgtcc attttgtcca
    30661 acactccaag ctaagccgga taaaaatccg atcaagaaaa tccaaggggt gattacagga
    30721 ctaacaacga aaaagacaac taaagaaaac agaaatgcac cgatcgtcat tcctagtgtt
    30781 tgttgattgg catcgccacc aattttacca cttactaaac caatactacc ccatgccaac
    30841 atagggacta atgctattaa aatttccata accaatctcc ttttatttca catgataaga
    30901 aacttatcag cgaaaacgtt aacaacacaa gcactttttt tcgtttctaa cgattttcta
    30961 acgtttttca ttataaaaat ttaagattgg gaaaaataaa gtcattgttg tcccttttcc
    31021 ttcagttgat tcagccgtca aatggatacc taatttttcg gccagatttt ttgctaaata
    31081 aagtcctaat cctgttgaat gtgttttgct aagtcgacca tttctcccag taaatccctt
    31141 atcaaagatc cgtttcaagt cttccgctgg gataccgatc cctgaatctt taactgaaag
    31201 gctgactcct tgcgcttcct tttctatgct cacaatgatg tttccgtgat ccggcgtata
    31261 tttgatggca ttactaagca attggttgaa gataaaagcg atccatttag catcggtcaa
    31321 aacagtatga tcctcaccaa cgatctcgta gcgaatattt ttttggataa aataatttgc
    31381 ctgactgcgt atcacaggct gaatgattcc ttttagtcca tattcttgga tgaggtagtc
    31441 ccgcgagaaa ctgtcgagtc ttgcataata caaaacttgt tctacgtatt catcgatttt
    31501 tgataattca ttttctagta atgtatactt ttgatcgtca atatcgaact cgatcgaacg
    31561 aactagcaat ttagaagcgg aaagtggcac tttgatttca tggacccatg agtcaatata
    31621 atctttttgg tcttgttgat tactgattgc tgattgcatt acttcttggt gttcacggat
    31681 cagctgattg atatattctt ctaccagttt ttcttcttct gtcctcccac cactcaaata
    31741 attttgcaaa ggggaagttt tttgtatgtc ggctaatttt ccccaccatc ttctcttgct
    31801 caagtaacca cccagcagat aaaaaatcag aaagacgccc tcaatcaaag ctaaataagc
    31861 aattgtgctc aaatcaactt tgatgtttgg cgccagccac atcacaaaga tcgtcaatgc
    31921 aataaaaaac agccatccca agatcaatgt ccactgatct ttcaaatatt taaaaaaatt
    31981 catcttaacc gctcatcctt tcagggaacg atatatccct gtcctacttt tgtttcgata
    32041 tatccttgga tacctgcctg ttcgattttt cggcgtaacc gattgatgtt gactgtcaat
    32101 gtattgtcat ctacaaatcg ttcgtcatcc cacagtgctc gcagcaattt ttcccgactt
    32161 aagatctttc cattgtgctt catcaaaata aataatagac gatattcatt tttgctcaaa
    32221 tcaatgatct ctccgttgat ttccatactt ccgttgtcaa cattcaacgt aatgccattg
    32281 tggctcatca tttcactaga taattctgtg tagttgtaag aacggcgaag taatgcattg
    32341 atttttgcaa tcagtacatc gatttggaaa tgttttgtca caaaatcatc tgcccccatg
    32401 ttcatagcca tgatcatatc catattcgta ttcctgctgg agataaaaat gatcggtact
    32461 ttcgatactt cacgtatttt ttgacaccaa taatagccat ccaaaacggg aagattaata
    32521 tctagtaata caagctgtgg ttcttctctt tcaaagtctg agaacacttg attgaaatcg
    32581 gtcgttccaa aggtttcaaa ttgccatttc tcaagttcct ccatgatcaa ttgtcgaatg
    32641 atctcttcgt cttcgactac catgattttt gccataaaaa atccctccat ctttcttctt
    32701 gctactacaa tatcaaagaa gcccttgtga aacaagttgg cttacctgga aaatgtcatt
    32761 ttagcaaacg ttaaaaaaaa ctggaaatat gcgatttaat cgcgtttgtc tcttccaagc
    32821 agcttaaatt tattatgtta ttcttaataa ttggtctatt atctgttatt tttctttcgt
    32881 tgtttttgtc ttttaaattt tcgataacac caataaccga aaagcgttag cactagcaat
    32941 atacctagaa ggagtataag taatcgataa agatggtatt tttttgtctg ttctatcttt
    33001 gaagagactt cttctgtaaa gggaactcgt cttcctgtca ctagtaatcg gtgagtgttc
    33061 acggtgtaag gtgtacaagt gataagtgtg actagatcct gcttttctct aattgctaat
    33121 gtatttgttt ttgttggaag gacaacaatt ttctcaacga cttcataagc gagcatccga
    33181 ccatacactt caagatagaa tcggtcatct tgctccattt cttcaagatc cgtaaagagt
    33241 tttttctcag caataccgct atgggcggta atcacggaat gtgtactctc tcctccagtt
    33301 ggaaaagagg tgccttgcag gactgtcgct cctctatcta acaaaagatc attcgtttca
    33361 tcaaataaag gcaagctaac attgattttc ggaatataga tggctccgat catatgttgt
    33421 tcgtaatatt cttttcctgg attttggaca tttctaaccg cttgctcaaa aggatctttg
    33481 acttgtccca ttcctgggat tactgatgta tgagcaagcg tctgattttt cttttcatgc
    33541 actgctaatt gttgctcatg tttttcttct ttatcgcgtt caagctgctt ttgataattc
    33601 tcgatccttc tttgatccaa ataattgctg agagcatctg ctaaaaatgg atatgtaaaa
    33661 actgcagctc cggcaagaaa catcactgcc ataaataatt gtaataaaag actgatttgg
    33721 gtttgaggtc tattacctat tttctttttc attttcttca ccttcttatt taaaaaaact
    33781 gcagcaacct ttataaaacc gattgctgca gcttattttt gttgcttata cttcagactt
    33841 cattttagat ttacggtacc agctgtacgc tccaatcatc aaacttattc cgattagtaa
    33901 gaatgccaag agcccgttcc caccagtagc aggaagtgac ccgcgtttca tattcggtac
    33961 tctttctggc cctggatttt ctactcctac gatctgaatt tcttcattat agcttccata
    34021 agagatgata aattcagtaa aggctgcctc acctgttgga agtacataac cttctggcgc
    34081 catggtctct ttcatttgat aggttccata atctaaccct tgaacctcaa agtatccatt
    34141 tccatctgcg acaaattctg ttgcttgtcc gcttgttgcc cactcaattc tatctgctcc
    34201 tgattcataa acagctaaag gcgactcccc tttataaaat attgcgtatt cagaacggtc
    34261 ttcattccac aattcgaatc ttgcatcttt aagcaattca ctgcttgatg catcatattt
    34321 ttcaaacttt cttccacctg ttgtgacttt ctctggcggc tctactcctt cttcataatc
    34381 aaattcatca tttcgtccga tttcaataac cgctgtgttg ttatggaaat catccgcttc
    34441 tagttctgtg gaaaccttca aattatacgt gatcgttaaa tctcctccac gtgcatctgc
    34501 taatctacct aaagtatcta ctttggctac tccattttct tctgtcaaaa tcgtcacgac
    34561 aaacccgttg cttactactt ctactatata atcttgtcct tttgttaaaa tcgtctcgcc
    34621 ggctcgcact tctatttcct gatcataata agttagacca actgtaggcg tatctgtgat
    34681 tttgtaattt ttgataacag cgcttccgtt ttcaaggaca gaatcgatga aataaggaat
    34741 aggtgctgtg atcgtgtaag aagccgtttt tcctctttct agatcaatat aagaaatcgt
    34801 ttcttgttct ccagcttcat taataatcgt tacttgtcta aggtcgcttt cctctacatt
    34861 catctgttta tctgcttctc tgatttcgtt tttcggatac aaatgcacat ctgtattgta
    34921 tgtgtctttc catgtagaac catcccacac gccatccacc atatcaggca tcatcactgg
    34981 catcataaca accattggag acgcgattct ggaaatatga gctggcgaat aagtttctaa
    35041 gaaaagatag actttatctc tagaagaagg tgcttcttcc gtcacttgga cggtagagaa
    35101 taccgcttct ccagcttcat tcgttgtttg tttgtcaata cttgtcagtc gatattttaa
    35161 aaaccaactt tctgtgtgcc gtttttgaat ccattcaatc gcttcggcag aattaagacc
    35221 gtcttctcgt tccggtgtta aaggattatc tcgaatcaaa tcgtaatata cttccgttac
    35281 gtcaaacaaa tcaaaatcga ctcctggaat attttcttca ccaaaatccg tagaaaccaa
    35341 tccgctattc ggtcgttctt ccggaacaga tgagaaacct tttttgtgta atgtaatcgt
    35401 cacttcactt ggtttttgtg cgacttcttc ggctttgact agttttccgt tcccgaaaat
    35461 ccctattccc gcagtaacga gtaacagtac actcattccc gtgacaatca tttttttatt
    35521 catttttttc tccccgttct ttttttatta ataaaacagc acctaacaat aaaagaattc
    35581 ctagtaaaga aatcaacgtt cttgcttcat tcgtttgcgg gaatacggac cattttcctg
    35641 attgacctgg attgcttgga ccactcggct ctttcggttt gtccgttgtt tcttttacgg
    35701 tctcgttata aacacgtggt gttgcggatt cataggcaga gactggaact ttcccggatt
    35761 ctaattcagc catctcctgt ccgttaacta ctacatattg tggttggcct tttgcatcca
    35821 cccaaaattc agggatgatg acctcgattc tcttacttgc ttcatccatc tcgtaacctt
    35881 ccacaccttt taattcttca aaataatagg tgccagaagg caagaaacgt tgtcctgtcg
    35941 taacaaggcc ctctttatcc gaaatgaatt tgcttacatt tttgtcattc aaaggatcat
    36001 tgtctgctgg tttgatccat tgatttttca agtcattagc aggagccata tctaaataat
    36061 atttcccccc ttctatcatc tgatatagag caaaaacagc accttctaat ggttttcctt
    36121 tttcagttgt tcctctttga cgtccatact tgaagaagta tggatctctt agataaccga
    36181 catttttagg atagatatga atctcttgca gttcctcggt tgattctgtc gggtgataaa
    36241 ttggcaaaat agcagcaatt gggatagctg tctgatcgat atcaacatcc aatccaactt
    36301 ctggatcaat cgattcttcg aaaatcaaat aaactgcatc ccgatcttgg tttttcttag
    36361 gtgctttgat acgtgcaatc ccgtctccta atccgccaac cgtatctttc ccagttgtta
    36421 ccgaagtccc tatttggaca agcctttctt ctgtgattag ctgacggata ttgtttctgt
    36481 tcgtttcagc gatttgctgg acgaattctt taggagtcat gttttcagca gctttttttt
    36541 catgataata atcggtcatg tcgtaaatgg caaatgtcgc tccatttagt ggcaccgtct
    36601 gtgaaatgat atctgctgtt tcccctgctt cctcagagat agccaagcca tcattttcat
    36661 ggtattcaaa ttgatcgtta taatcgatat ctcgaatcat ccgtttatgc aacacgaatt
    36721 ccacgacatc ttcccctgat tcttctgccg acatcgcatg tggaagaagg actgctgcaa
    36781 gcggtagtaa aacaagtaat tgaagcatca aacacaacag ctttttcatt accttgctcc
    36841 ctccttttta gattgtctga caaacaaacc ataggctgct cctgcaagcg ccatgaagaa
    36901 tgcagcaagc aggatataga ataatcgtcc ggatcctcct gtagcaggca acggattttc
    36961 aggatcgttc ccgacactaa gctgtaatct gattcgattt gtctccaaaa gttcatattc
    37021 taactcttgc tgtagatcag gcgtctctgc ttcttcgttt ggataatacg aaatctcaac
    37081 ttttagtgta cccgcttctt ttcctggaac tacccgatca ttttctatgt caggttcttc
    37141 tcgataacta atttctaaaa taaagtaacc tggaagtttt ctatagctgt caggtgactt
    37201 cacttccttg atccgataga ccccttccaa caagtctgaa gcattgaata gggaagaatc
    37261 gtttggatct ggtgccaagc ctccctcgat gatttcatac tctcctgcac tattttgttt
    37321 ctcaattgaa aattctgcgc cttcaagacg tcggctattc atactgtcaa ttttcaaaag
    37381 ttccaaatcg attggcgcta gttcatcttc taaggttact tgtagtacac catcgatgat
    37441 ttcatagcct tccggcaagg gagcagtttc gtcttcgatg accgtatctt caatgataaa
    37501 cttaccttct tcattcagtg caaactggaa cacttgatca gatagccgat acccatttgg
    37561 tgcgacagat tccgagacct catattcacc aatagacaga tgcagaggtt ggtcgtaatt
    37621 taaatcgaca tacttttcta ctcctacggc acgagaatag aagtatccga tcccaggcaa
    37681 acgtttcgat tcttctggtt ctaacggatt accagtgtat gctcgataca gcgggaagga
    37741 agaatccccc actttcctga tatcgaaacc tgcaccatct aatgtatggc cttcatggtc
    37801 taattttcta actcggatct cccgataatc aaacgtattg taagcagtga atgctaccca
    37861 taaacgatcc tcttcatctg ttgtatacgt gagatattgc caattttctt cacctgtttg
    37921 cttgagttgg atagtcccta tagcattatc gtaaagtcgc aagatccatg tgtcattttc
    37981 atcaggttct ttgaaacctt ctgggttctg gctctcaatg attttgtatt ctgcatagtt
    38041 ggtagtttct tcactatcct tataaacaaa tgaatctggc tctccgattg gatgaataac
    38101 tttctcacca tccacgatta catatttccc gtcttcatct actgaataga acgtgagtct
    38161 ccctttctct tcctctactt cgttcacacc agaaagccct ttcgctactg gatatccgat
    38221 ttccagtccg ttaccatctg tttcataaag ttcaaactct gcgccattga ttggcatatt
    38281 actgccttca attagtttat tgatattcat gtggattggc ttgaattcat ttcgcatttc
    38341 cagtttgaca tacaactcat catactctgt gccttctatg ttaggctctt gtacaacaga
    38401 aagcttgtga tattctcctt cataatagga attcggatct ttaccttccg gtccgccgac
    38461 tctcgaacca gatgtatatt catctacaag ctcgtagtga cctaacatct catcttcgtt
    38521 ggctgcatat tttttgattt ggaattgata cgtctcatct actaactgat aacgtggtgg
    38581 tccagcgatc tctctgatcc aaaatatgtc gctgactgct ccagtttcat ctcctaaaat
    38641 cggcatcttc gtttcaaaga tcgctattcc gtccgtggta gttttacttg tttcgattgg
    38701 ttcggcttcc ccactctctg gattttggtc atataatgca aattcgactc cagccaacgg
    38761 ctcgccattt tgacccttct tgctgacttg gaaattacgg cctttatgtt cgtaacgaat
    38821 ggaagaagat gggaaataca tccgtccagt agtgatatca ttctcataat cctccaggtt
    38881 ctgaatatag gccatattgt tcactgtgca aaaatttccg tcttgagctc ccgcatcaag
    38941 ttttacttgg tacttgatcc tgaccatttc cccttcacct aaagaaatcg gagaaaattt
    39001 ataagcttgg ttttcccgtc cgacatacgt tgtcggagtc gccactactt ctggtggggc
    39061 ttgtccatga cgttcttcat cccatatttc tggctcttgg tacttcatgc cgttttctcc
    39121 tggatctaga tggtaaaact gaatatctgc cgatctgcca gctccaaatg gtgagacatt
    39181 aaaaccagtt tcatcataaa gtgtggcttg ctggatcgtt ctcttgaagg tagaagagat
    39241 atcctccaag gctgtaacaa tgtcattctt gttgttcgca ttgtaatatc gcggtgttac
    39301 gccatcttct tctaaatcag caatattttt caatacattt cgtccaatag catctagtcg
    39361 ttgtctcccg ctaacgtttc catcgattcc taaaccaatg gagaagatac ttggcgggtt
    39421 ctcttgatac ttgtttttca gccaatgatg ataagcaact gtgttgatcg cagatgactt
    39481 ttcttgcgaa gtaggactgc cattcgtatt gttattagaa gaaccatcac caacccagtg
    39541 agtcgcttta ttatctcctt cttttacctc tccataacga tagtgtacat ttacttcatc
    39601 ttctggacgg ttaaagtcag atgcataggt aactggatga gtaaaccctg cattagaagt
    39661 attcccagaa aactcctcaa aatttctgaa caaaacgtca ttatcttcag caatcttatc
    39721 ttccatcaca gtccagttgc tccaagctcc attagtgctc gtacgataac ttgactgaat
    39781 cggtgcataa ctgaaggtcg gtgtcccatc tcccacaacg attaggattt tttctggatt
    39841 tctattttct ccgccattgt ctttatacaa tgtttcatag ccatttttaa gccctagtgt
    39901 aagcggagtt cctccgattg gtgtacgatt taatgctgta ttctcacttc ccgtcaaacg
    39961 attgatatca tttgtcaatg gaaagatgtc cgaactgatt tgctcatggt tattgatagc
    40021 tgtactatta tggtaaaaat tcaccatacc gattcgaata tccagactcg ggtcagagag
    40081 cagatcttta ctcatttcgt ttactgcctc aatcaacgca gcatttttag tttgactatt
    40141 ggtcccagcg gttaattcac tcatactcgc tgacttatct agaacaaaaa cgatatcgat
    40201 tggactgatt tcctttttct cgcccccgat gacatctaga tagacattgt aaagggttgt
    40261 tgcatcttca ggatgtagat cagatgctgt gctgcttggc agaacaggtt ctacccattt
    40321 tttgatgtac gccccgttat aatccaagta actgttttca aaattccgtt catttcccca
    40381 aagctgaacg gtttgagctg gaacgtttct atcttcttcg cctgcagttg atccattatt
    40441 agtagcatag tcgtaatttc gccagttcgc tcccccgttt gtataatcac tatcatcgat
    40501 caagttctct ccgtcatatg gcgagccttt gtctccttga tagcgttcat tgctttgtgt
    40561 ccaatttcct aacacttttg tatagtcatt cgttgtaaac ttcatctatt ctttcatcaa
    40621 ccaccacttg aagaggtagt tacccttcgt tcacatcggg gatcttttct gtttcaaaaa
    40681 tcaatgtgcc ggtttctgct tcttttgaat aaacttttcc gacataccat tcttgaccat
    40741 cgatcgtctc gacttttagg tcttctccat cttcatcata ggaggataga cctgttccac
    40801 gaacgttttt tacggtacca atcccggcgg ctgccgcatc gattgctaaa cgtattctac
    40861 cttcattggc actttccttt ttttcaaaag ccagatgcca ttcaagggtt tcttcttttt
    40921 caatatactt cccttcaatt tttgcatagt cctcatctaa gaatacctca tcctcctttg
    40981 tttctgttga ctcagcagct acatccaggg tcgtcatatg atagactgac tggaaatatg
    41041 gtccaaatag caaactgaca gttactaact gcaaaagctt caattttaac cctttcacat
    41101 ccttatactc ctttcaaaaa tatttgtctt ctttcacaac aatcaacaaa acaatgccca
    41161 tctaattata atttaattta attttaattt taaatcaaat gatatccttt ttagttaaaa
    41221 aacaccaatt atacaacatt tattattaaa attaaattat aaaattttat aacgttctca
    41281 tttaacaaaa cttaagttat taagacaaat gaataaacaa ctacgctttc ctcgaaacaa
    41341 aaaaataaag cacaaatgcg catttacgca ctcatgcttt attcgtacaa ttaattcaga
    41401 taacggcagc gcataggatg ccaataacac ttcctaaaat agctcctcct aaaatgtcag
    41461 taggataatg taaaagtaaa aaaatcctcg aataagcgat caaacaagca aataaaaagg
    41521 ctaatattcc tgcaactgga cttaattcga acaacgcagc tactgataaa aaggctagcg
    41581 ctgtatgtcc tgaaggaaaa gaagaagtct tcggtttact tgtgtaaagg acaagccgac
    41641 gatttttttc ataaggtctt ttccgtcttg tcgttttttt gataaaaagc aaaccaacaa
    41701 aaaaatagat caaactgccg ataagaatgg ctagaccata ttctctagta tcaggtatca
    41761 agactaaaac agcagcaagg agcaaccaaa taaaaccacc attagagata ttactgataa
    41821 atttcaaaaa attgattttt cgactatccg ttttccgttg cttggcgaac ttgttgataa
    41881 tactatcatc gattttagca atcaaacgca acatgttatt cctccttttt aagaaccttt
    41941 tcttgcgtac gatggataaa aagcaggact tgaaaataaa acaagaaact gaaacctaat
    42001 aaagcaaaat agattggtcc tgcaaaccag aatgcgacaa gaaggatcaa cgtgcctgcc
    42061 aaatagaaaa gcgcgctttt gaaatcatta aaaaacaaga aaaatgcagt aatccaagaa
    42121 gcttcttttt gttccagttg aagcaagatt ttgtaactaa agagaagcgc gcttaataga
    42181 agcaaaaaca acgtagtata catcaatgta tagccaattc ccccacccca atagcggaaa
    42241 atctgataat cgatcaatag aagaagaaaa taaacacttg ctaaactatc ttgctttcca
    42301 taaaaagaga agttctcacg aaactttttc cagaatagtg aaccgagctt tttctcttca
    42361 ttttttttgt aatgataaat catatacaga actgttcgac ttgcagttcc taatgtgaaa
    42421 acaggcaaga cgcacaggaa ccatagtagc tgtaaatgga taagacgtgg aatccattca
    42481 atgatttcta agaaataatc attggctttt ttaccaatcg atcgattcat catccttttg
    42541 aacctcctgt caaatccatc ccttcaatga aataacgttg tgcaaaaaag aacagcaaaa
    42601 tcgtcgggat caagacaagt gttgctcctg ccatcagata attccattgt gtcgttgctt
    42661 ggttctgaaa aacttgcaag ccaatctgta acgtgtattt ttcttgatct tggatatata
    42721 acagaggacc taagaaatca ttccaagctg cgttgaagga attgatcgca atggtaatca
    42781 aggcaggttt cgtcaatgga agcatcaaat gactccaaat atacaaatga ttcgctccgt
    42841 cgatttcagc agcttcgatc aattcattat tgatcgataa gtaaaattga cgcatcagaa
    42901 atatattgaa cgcattgccg aagaacgatg gaacgatcag gggcaaataa gtacctaccc
    42961 agccgatctt ggagaataat acatattgag ggatcatcgt tacaaacccc gggatcatca
    43021 tcgtagaaag aaccaaagca aacatcagct ttttcccagg aaaatcaagc ttcgcaaatc
    43081 cataagcaat aaaagaattt gaaaggacat taccgatcac tactagcaca gtgatgaata
    43141 atgtatttct tgcatagcgc caaaaaggaa aggcggcaat cgtatccaga tagttttccc
    43201 atacgatttt ttctgggaaa aaggtcggag gataacgaac gatttcttcc attggtttca
    43261 atgaagtaaa caccatccaa agcaatggaa tgatcaaaat gattcctatt actgtcatga
    43321 ggacataact tagtattttt tttgtttgcc gattcacact ggtctttttg aaataatcca
    43381 tcatttgccg tcacctccag aataatagac ccacttaggt gcaagcttca aattgacaaa
    43441 cgtcagaacc aacacgatca gaaacaggat cattgacata gccatcgcat aacccatatc
    43501 aaaagctacg aacgccttgt tccacatatg cagattataa aaaagcaaag aatttgcagg
    43561 tccgcctgtt ccatttttcg tcatgacata agcttcttga aaaatttgga aagaaccgat
    43621 cgtagaggtg atcacatcgt aaaaaataat aggagtgatt aatggcaaag taatactttt
    43681 gaactttccc caaacgcctg ctccatcgat ttctgctgat tcatataaag atctaggaac
    43741 attttgtaat gtagctaagt aaagtagcat tgctcctcca gaactccata ttttcatcaa
    43801 aatcaacgca ggtttcgtcc attgtggatc aaacagccaa gctggtccag ggatatggaa
    43861 ccagcccaga aatgtgttga tcaatcctgc agatggagaa agcagctgca tccataagat
    43921 gtagactgct actcctgata agactgccgg taaatagaaa gctgtacgga atacactgat
    43981 tcctttgatt ttttgattga gtactgtggc taaaaacaca ctgaaaatcg tcgtcagcgg
    44041 tacattgaag atgacgaaat aaacggtgtt gtataacgat ttccaaaata aatcatcgtg
    44101 aacgaacatt cttttgaaat ttgctagacc aatgaaattc atcttggatg tcaaattata
    44161 atcggtgaaa ctaccaataa ctgaaaaaag cataggccct agcataaata ccaagaaccc
    44221 gataataaaa ggcgagataa ataaataggc ccatcttgct tcttttttct ttcggataga
    44281 taaacgcttc aaattttctt gcctcctctg tacctagaca gtcaaaaatg gattattgat
    44341 tttgcttgac taagttttct actgcttttt gtgcatctgc caatccttct tttggtgatt
    44401 ttgttcctaa aagaatctgg tcaatctgtt cattcactaa tgtcgtgtaa tccggagcat
    44461 ctaaaggaac tggtgtgatc accgtatttt taaagttttc gtccgccatt tgatagatca
    44521 tttttccttt atccgttagg ttgtcattat tcactaaatt ctcattggct gtcttgctcg
    44581 ccatgatatc aaaacttttt tcgccgaatt tttcttgtac ttctggagaa gaaagatatt
    44641 tgatgaattc ataagaggcc tcaggatctt ttgctccgta tggtacttcc aagacgaatc
    44701 cgccacccca cgaccaatgg cctgaacctt cttctttttc tgggagctgc atcacgccaa
    44761 aatcaaaatc atccggtgca ttttccatca aactagagta ataattgata ttttgggcac
    44821 gcatggctac taatccggaa ataaatggat cagatacacc agacccaaat tcggcttcta
    44881 atttattgat cgtatttttc ccataataat cttgccagtc ttggatccac tccaaggctt
    44941 ccactttatt tttagtatca atcttgactt tttcatcttt gtcaaaccaa ctagtcccgt
    45001 tatctgcgtt tagcgcccat acatcagccc ctaaattcca taatggataa aaaccgatgc
    45061 gtgtaaattc ttttccttct tttttatcta gtttacgtgc tgtttcttct aattcatccc
    45121 aagttgtcgg tagatcttgt tcactgattc cagcttcttt aaataacttt ttattataaa
    45181 aaatgacttg tgtatctgta ttgaatggga tcgcataagg atcaccttca tattctactg
    45241 tatcccaaag ctgcggataa aaatccttag aagtgtcttt ttctacatat ttggagagat
    45301 tagttgcttg ctgtgcttct gctctttggg caacggaatt tatgtcctgt acaataacat
    45361 cgggtgcatt tccagctgtt attgcagata aagatttagt ccagatgtca ccccatggct
    45421 gatacttata atttacatgg atctcgtttt gtgattgatt gaaatcctca atgatttctt
    45481 cgatagcttc ttttcgtgca ccggatcccc aaaaggacca gaaatcaata ttttttcttc
    45541 catcacttgt tttttcagaa gaatttgctg cacttgaact ggcatcgctt gcattacttg
    45601 atccgcatcc tcctaataaa aacaatgctg aacttgccag caaccctgta aacaataatt
    45661 ttttcatatt ttacctccaa attttaatgt aaccgatgcc ggttttaata taacgatatc
    45721 attttgttct gaaaataaca atttataagg tatgattcta aaaaaattat taatgatacc
    45781 aatactttat ataattcgcg agcgctttct ttgaattttt taatctttcg tagcagaatg
    45841 agaatgtatt aaaaatagat taggaggaat tttgatgttt agacaccaga aagaattgca
    45901 gtttgaagca aaaccagatc gtccgaatcc attaatcgcg aaatatctgc aggagctgat
    45961 cggcggccaa tatggcgaga tgagtgtagc tatgcagtac ctgttccaag gctggagctg
    46021 ccgaggagaa gaaaaatata aagatatgct gatggacatt gcaacagaag aaatcggcca
    46081 cgtggaaatg ttggcgacaa tggttgctcg tttattagag ggtgcgcctg ttgaagatca
    46141 agaagcagcg atgcaaaaag atccaacaat cggtgccatt atctctggaa tgaatccaca
    46201 gcacgcgatc gtagctggct taggacctcg tcctgctgac agcgtgggca atccatggag
    46261 cggtgcctat atcattgcga gtggcaactt gttagcagac tttagagcta atttaaatgc
    46321 cgaatcacaa ggaagacttc aagtagcacg tatttacgaa atgatcgatg atcgtggcgt
    46381 aaaagatatg ctgtctgttc tccttgcaag agatagctat catcaaaatc tatgggaatg
    46441 tgcagtgaaa gaattagaag aaaaagaagg ttcaatctta gtcccaagta ctttcccgcg
    46501 tgacaaagaa cgaaaagaca ttgcttatga cttctataac ttctcagagg gagaccaaag
    46561 tagtgaaggt tcttgggcta gtggcaaagc actggatggc gaaggcgaat atcaatggtt
    46621 gaaagaacct aagatcgaag gcgctgcacc aaaattagaa ccagtaacac caaaaatgta
    46681 tgggacacct ccattcaaga aataaatatc tacccgtaga aacacccgtt ttttgttcca
    46741 cacgctttgt gagcaaaact gactaaagtc attaatcata accacccttc aaaagggtgg
    46801 ttttctctag agctataagc tcaaatcacc ggccagcgcc taaagacgct ggctttcata
    46861 ttttatgttc aagccatatt gcctttgcca gttttgccca cctcttaaaa ggtttatgta
    46921 ctactcctta gcccttaaaa ggatcgtctt actctcgtac actcagctta tctaacgcac
    46981 tatcatgttt ttcttgttct tgaatgtact ttttgatggt cgcttcattt tgtcctactt
    47041 ttgtcacata gtatccttcc acccaaaagt gtcgataccc aaatttatat tttagatttg
    47101 cacaatctct tgatgatctc ctgaatattg gctcgatatt gattataaat tatttttctt
    47161 ctatactttg gtgtgaatac aatgtggtat ttacacatct actttgtacg ggctaaacta
    47221 tttcccttta ttgctccacc cgcatagcaa gtggttttgt atttcaatcg ctcggcgcgc
    47281 tcaattaggt ctaaagacaa taaatctaaa aacccgctgc ttcactgaca gaaacaacgg
    47341 gttttcagaa aaaaatgaaa tgaaaaagat ctcttacggc aatctatttt atttttttga
    47401 ttttttataa atggaaaatg cttcaagaag tccaagaaat aaagccgtat aaaaacaaga
    47461 acctatgaaa tctttattta ttagatattc aacagaaatc ccgataacac tagccaacaa
    47521 tatatttatc agaagtgtaa aataaggatg ctttttatag aatagaacta gtgttgtttt
    47581 catagactct cctttcttca tatttccaat taatcacaaa ttcacggcat tactagaaaa
    47641 attaaagggg cgcagaagtg gaaaaatact cttcgacttt ccctacaaac caggccatct
    47701 tgtgtttaat aactatacca aatctaaggt acctctaaat ctaaattcca tttgtggcgg
    47761 tgacctccaa tttttaactc ttctatctcc catccagtat acataacctt gatacttcga
    47821 ccacttatat atcgaacaca caaataccta tccattgcag gagtactacc taacttagtt
    47881 gctacttgca tctaaataac agctgaaaag ataggactta ctcttagtaa agtatctgaa
    47941 ctattaattt ttaaactatc atttttatcc tcaactacat gcacatctgt tgcaacttca
    48001 ctttctgtct catccagata aatgattaag gaatcgggaa ttgcaatatc ttcagctgac
    48061 gctggaatag ttgagctaaa ttagtcatca tatctttatt ataaaataac caacagcaaa
    48121 aaatacaatg aaaaacaaac ttggaactaa tgtatcatta ataaatgttg aaaaattcag
    48181 caactcatta ctgtatgatt ttagcagccc aaccaacata taccctataa aagctaataa
    48241 gatggttagg aatcctttag aatttttact cattcataga cacttcctta aataactttt
    48301 attatagaag gtattgtaaa taataatatt gacaaaaagt gactcaaaat aaaaaaaaac
    48361 ttacattata ctggaatgaa ctgtattgat agtgtaccta aaagctctac tgacataaga
    48421 tcgtgtaatc ggtaaagtaa ttttattaat tatacgggat gtaatcaatt agagaataaa
    48481 ctaatcataa aaggtacttt tacattcata attgtcgctt tgagattcta ctttggttca
    48541 ctatctgacc caattgcaca ttttcgatca ttacaagtat tggtgtcgtt agaacaacta
    48601 aataaaaact agcggtagat ttttcagaat ctatgctaat ttctgtatgg atgttccagt
    48661 gatggcaaat ttctcttttc attgtttttc ttgtcgcatg atatgccttt ttgtgttatt
    48721 cagttaaact atagaaattc tttcctagac agatcttgat cccaaatttt acgtttttga
    48781 gcatcgatat agtttaaaat gacattactc atatctaaag agtttagatt ttttaggact
    48841 aaaactgtca gttgttcttt ttcttctttc tgttaaagta ttgtcgcgac ttttcgtata
    48901 cgttaagata tgtcgtgaaa aaacaagttt tgtgacacaa aaaaacgaat gacttgagga
    48961 aatcacctca atcattcgtt taaaatgcta tatattcttt agtttaagat acggaaatta
    49021 atgccatcga ccacactagt agaatgaacg acatttactt ggcctttttt taatttcgtt
    49081 atgtttagca tataaaaata ttatagagtt tacttacaat gcttaaaaca tatactgtat
    49141 aatctgatca attttagcca tgtcttgcaa tggtaagttt tctatttttt tgagttttcg
    49201 ttccttaaaa tcaagagatt ttaattgtgt aataattact tgtcctttta tatctagctc
    49261 ttcaggtaat gagtaacgtg tcggtaaatt ctttatagtg gaagtaattg gacatatgac
    49321 cgaaaacatt gttttacggt taaattcata acgagagacg actagtcctg gtcgtctttt
    49381 ttgaatttct tttcctacgg agggatcaaa atcaatccat acaatatcac cttttttagg
    49441 aatataaatt ctttcttctg acactataaa atttctctcc cttcaggagt taaatcttcc
    49501 cattcgtctt tctcataata ctcggcctct tccccaccac taaatggatc ttcaattttt
    49561 ggaactaacg taattgttcc atcatcagaa tacacaacga tatattcttg gttttctgaa
    49621 ggtttctttc cgttatcaga aggtaaagtt accactacag aacttccttg taatctagat
    49681 tttgtaacaa gcattatcat cactccctta ataaaagtat actatataac actaagtaac
    49741 gcaaaattcc cctttgtaaa ctatctagaa aattgttttg tttaaagtat atcttattgg
    49801 atataaatag aaataaattg tagccagttc attttttctt taactaaaaa aataatccaa
    49861 gaaacattga acctatggat ccaaaagcta cccaaatact atagctaacc ccccgctacc
    49921 ttcaattttg cagataaaac gctttgggag aaaatttcaa agacaacagg ccatcctatc
    49981 atgcccgatt ataaacaaaa agctggctat tccttttgct ctgacaaatt tcaattggga
    50041 aagttcacga aactagcagg tgaagaagtt tcaactgttc ggatcaaaga atgcccgctt
    50101 caaatagaaa cattggttca acgaatttca actagacaag actttgctat tgtagaacgt
    50161 gagatcgtag ctatttttgt agaagaaggg attttacatg atccaactca tatcaatgtg
    50221 gataaatggc aacctcttat ctataaattc agagaatata caactgccaa ccagtcgtta
    50281 actttgaatt ttagattcca agaattcaaa gagtcataat gataaacatc gttaggtata
    50341 aataaaaaag actcgcagca cgagtaaaaa acaaatagaa gctatacatt agaaaggtcg
    50401 actgtgaccc tatagatgca gtatatgcag cttatgagca tttcttctgt tctctttgtt
    50461 tttgggatct gtgctgaagt ctttttcgtt ttttgccgct ctttctttga aaaatcgatt
    50521 atgttatacc ttctccatta ctaattcagg catctgctga gtaatgattt ttcgcgcaaa
    50581 agaaatatct gttacccaag gttcgatttg ttcttcagtc aagacaagcg gcattcggtc
    50641 atggattggt gcgactgtgc ggttaggttc agtagtcatt atgattgatt ctgccatttt
    50701 ttcatcctga tggctacgat aaaaaccgcc aatatacact attttttcct tatttgaaaa
    50761 cataaatttg tctttttctt cattccactc attgggaaaa cacaacgatt ttgcaaaaat
    50821 ggttgatgaa aggtcttttt ttcttctact gtctctgcac gggcattaat catcaattgt
    50881 ccttttttaa atccggtaaa tccccacttc atgatttccg gagtgaggat gttttcttcc
    50941 tcttttctta acgtcacaac aagatttgac ggaaaaactt ctccagctgc taattctgct
    51001 gcctgcttcg gttgtttcgt ctgggcttct cgataataat tctgaaggag ctctgactct
    51061 agatcaaaaa aataacgacc acacatccta atccctccca atcttttttt ctatcataca
    51121 ctgcaacaag aagttcgcac caacaaaacg ctttcaattt ttgtagaact aaaaaagttg
    51181 tgacaagtga caaactctcc agtgaatggt attctcctgc caactcctcg gtcacaagtc
    51241 acaatattca acaaacatga gaagctgctt tttgaaattg ttccttgtga ctcggagtga
    51301 aacggcaggc ttacgacctc tgggtaaacg gtgttcaaaa gccagtttct cggtattaag
    51361 ccaaatttat gcaaaaatgt agaaagctat tttcacaaaa tttttcttaa tactcgaaac
    51421 taagcgactt tttcacaacc tcttccttaa acggtgttca aaagcttgca tctgcggtaa
    51481 taagcccaac caaacgaaaa atatgagcag ctatttttat ttggctgttc ttattacttg
    51541 atgcagggca gctttttcac aacctctcca ctaaacgatg ttcaatcagc taaccttcgg
    51601 tattagctca aaaaacggca aaatatgagg aactattttg ccgtttgttt ctctaatact
    51661 caggtcaaag cgctgatttc acaacctcta atacacggtg ttccagaagt agcttcttcg
    51721 aaaaataagc cgaaatttca caaaaatttg agaagcaatt ttcgtaaatt ccttcttatt
    51781 tcttgaagct gaccacttct gtcacaacct ctaattatta aagaaccttt tgcgaagtta
    51841 acaatctttc tttgaccaat tgaaaattct gcctaagtag tgatagatcc tgtgtgactt
    51901 tcaacaataa gatacttccc tggatttcag caatcaacgc tttggcttga cggtctgctt
    51961 cttcatcgga cagtttttct tcagaaagtg ccaggatatt ttgtttcgta tacttgaccc
    52021 attgattgac taattctagt agcaacagac ggtattcttc atccactgta ctcaactcaa
    52081 taatcaaatt acctacagga cagccatgat aagtgatctg tgtctcatga tcagcgaaaa
    52141 tccagtccaa catttcttct aatgcttctt ctggctgttt tccagcattt aagatgtctt
    52201 cgaacaattc tgtctgccat acgtccatat gcgcatggat caccgctaga caaacttctt
    52261 tttttgaaga aaagtaataa taaaattgac cttttcctgt atcagaagct gctagaatat
    52321 ctcggattga cgtttcatga tagccttttt tataaataag atctttggtc gcttccaaga
    52381 tcttttcctt tgttttcaat gatattctcc tttttcattt ctcatagtcc tatattatac
    52441 agtaaattca tcattttttc ttcttaatcg tttaaaaaag actgtgccaa attatctgac
    52501 acagccctca ctataaaact gttctcatat agctagatgt tcattgattc aagaactgcg
    52561 aggacaaaag caattcctat cttatgatag ttgctctaat acttcctctg ttgtcatcac
    52621 ttgatctgca ataaagccaa agttcgtcaa cgctgcatcc attgcttctt ggccaggagc
    52681 accaattgca tctgtcgcta ccacaacatt gaatccactc tctaccaatt cacgcatatg
    52741 ggaatcgcta cacaagtttc cgttcattcc accaagaatt actgtgtcga ttccattttt
    52801 tctcaattgg agcgccaaat cattgctttc tggtccaaag attttatgag gagagctgat
    52861 gatcgtattt tcatccaaat aaggtttcaa ttcttcgata aaatcggctc ctgaaccttc
    52921 ttccactgat tcatattgac tttttctagc aaacatctgc tgctcaagca tcatatgttc
    52981 tcctgcaccg ccaaattgcc atttatggtc atgtgggtaa aaataatgag gagaaataaa
    53041 gagtttgtat cctttttctt ttgcttgttt taccatttca atcatatttt cgatcgtatt
    53101 gtatttttct aagatatctt ttgtcaaacc aaagccaccg cctgctggtt tcaagaactc
    53161 gacttgcggg tcagtgagaa ctactgctgt atttttatta ttgaacatgg tggattctcc
    53221 attcgttatt tattttaata catcatttag agcttcactc attgtcggat gagaatagat
    53281 ttgatctctc aataacgtat aaggaagttt tccattcata gctagcgaaa tcaagttgat
    53341 gacttcatga gaatcttccg catagatact tgcccctaga atcaagtcag tttcagggtc
    53401 gactaaaact ttgaatacac ctttaggatc ttctaatact tgtgctttag ggacaccgct
    53461 tgtcatatac ttgaataatt tgtaattgac gccttgtgct ttggcttgtt tttctgttaa
    53521 acctacattg gataaagtcg gagtgataaa tacactgtaa ggcacagctt tccggttatt
    53581 cgttgttcgt ttattctcgc ccttcaactg atccataatg attcgataat catctagaga
    53641 gatataagtg aactgcaatc cgcctttgac gtctccaatc gcccaaatgt tgtctgcatc
    53701 tgtacgaagg tattcatcca cagcgattgc tccgcgatct gttagtttaa catctgtatt
    53761 ttctaatcca agtgatgctg tacttggttt tcttccagtt gcagccaaaa cttttgacgc
    53821 ttggattgtt acttcttggc catcttctgt aaaggtgacg gcagctgttg attcttggtc
    53881 tgctacttga tctacagata cacctagatg gaattcgatt cccgcatttg tcatgtcttc
    53941 taaaatcatt tgcgcgatat cttcatcttc acgtggaaga aattcagaat gggcatcaag
    54001 aacgacaact ttagatccgt attcattgaa cattgatgca aattccaagc caatatatcc
    54061 agccccgatg atcactaatt tttccggtaa ttgttcctga tccatcgctt gcgtagaatc
    54121 aatcaagtag cgacttgtat tcaatccttt gattggtaaa atgattggtt cagaaccagt
    54181 attgatgaaa atccgttcgc cttcaacaat cactttttca ccattattcg tcacttcgat
    54241 ttgatggtta gaaagaaaac gtgctgtacc gtccatcact gtcccagttg cctcatcgct
    54301 gatcatatga taatttttgg cgcgaagcat gcccgtcaat ttttctttcc gagcaacagc
    54361 ctctgtaaag tcgattcctc tttctccatt gaaaatcaat gatttagaag gaatacagcc
    54421 gatgttgata catgttccgc catacatacg tgttgacttt tcaacgacta aaaccgattc
    54481 accttttgaa gctaacgcct tcgctaaagt cttaccgccc tttccaaaac cgatcacaat
    54541 attttgatat ttttccatca tttttccctc gcttcttttt tacctaccga ttggtacaaa
    54601 aatatgataa ccgataattg tctattctcc aaatcatctg ctttatttgt caaaaaaaac
    54661 cagacaaaaa gcggtccttt cacgttttta gtctggttcg atttccttta ttcttctaaa
    54721 caatcgttac ttctacatcg atatttcctc tagttgcttt ggagtaaggg cagaattcat
    54781 gcgcatcttc tgcaattttt tgggcttctt cttcgctgat gccatcgata tgcacttcta
    54841 atactacacc gatctgatag ccgccatcat ctaaattata aagagagaca cgtgctttta
    54901 ctgtggactc tgctgtcatt cctgcttctt tgatcatatg ttgtaccgcc ccattgaaac
    54961 aagaagcata acctgctgca aataattgtt ctggatttgt tccttctgca tggattcctg
    55021 gaggagtgat tttcatatgc atcgagccat ttggtgcctc gacttctcca ttgcgcccgc
    55081 catggttgat cattgctgtt tcgtatgctt ttttcattgt actgctcctt tcgattgacc
    55141 atttgctact tggctataat tatagtgtat gacaagtaag gcgctttcta caaaaattct
    55201 gcttattcga ataccagaat gccgtcttct actatttttc caaaaaacaa aaaaatacta
    55261 ctcgtgaaca acagcgtcat atttgttcca aaataaatag caatcttttc tacataatct
    55321 tttatatgat tgattttaag atacatatat accagaaagt tgaccccata aaccaatact
    55381 gttaaaaaaa taaccatatt cgttaccatt ttttcctcct tttgctggtc tccctaccag
    55441 cactcgattt aaccatacca ctttttttgc cgtccaagca actagccttt caaaaagact
    55501 ggtttattct gctgttaatg attcaagatc agaaaaatgt ccgaataatt ttgctaattt
    55561 tactaacgcc aacttgttct ttccgaattc atcattttct atctgtaata ctagtaacgg
    55621 ctcatgtaag cttaaacgga tcaaaaacca gccgtttccg tatggctctt ctagatcata
    55681 tcgaatacct tcttcatttt ccgggtcgaa gttcatccct ttttcttctt ccaacagtcg
    55741 cttcatttct tctaatatct tgtttccttg ttcgcgtggt tcatcgctga acaattttaa
    55801 tcggatttct tgtacttcta cgggctgttt caactctttg atttgttcat ctaatgtgat
    55861 accttttctt tttaattctg gcaaaagcat caggatcttt gcgatgacat atgcaccatc
    55921 atccagaaaa tagttttcct tgaatgcagc gtgtccgctt gtttcgatgg ctagctgtgt
    55981 atctttccca agacggttaa gttctaatgc tttattgatt acatttcgat agccggaaat
    56041 ataacgaact tggatgcctc ctttttcttc aatgaatctt tgtagatgag aagaagtagg
    56101 ggaattcgtc acgattcttg ttcctggatg ctcttttaat acgattgtac ttaatactgc
    56161 gatcaaatta tttcgattga tcactgttcc agaagcactg acaactgcag aacgatccac
    56221 atctgtatcg aaaatgatcc caagatctgc ttcatttgct aaaacagcct gcttgatact
    56281 ttccatcgct tctttattat caggatttgg gatatgatta ggaaatcggc catctggttc
    56341 caaaaattgg gaacctgttg aatccgcacc taagctattc aatacttttt cagcaaagaa
    56401 tccaccagca ccatttccgg catcaacaat gattttccaa ccatttagtg gtttgctttc
    56461 tagtgttcca atcccctttt taatttttgt gactaaatct tgcgcataag gtgtcaaaag
    56521 gtctgctttt tctacgcttc cagtttgttc gctttttatt ttttgctgct gtgataggat
    56581 aaaagcaata tcttcttttt ctgctcctcc ttctgaggta aagaatttta ttccattata
    56641 ataataggga agatggctag cagtcagcat aaccgcagca tcgcacgaga actgttcaaa
    56701 ttgagtggac ataaacatag caggcgtagt agctaattcg aaatcgatga catgtatccc
    56761 ttgttctttc agactttgga tcaacgcctc tttcagtgct ggtccgctta tcctactgtc
    56821 atgaccaatc ccaatcgtcc attttttatt tggatcggtt gatttcttct ttttctttat
    56881 ccagtttgct agtccccagc cgatcttttt taccatgtct gtcgtcaagt ttacttcata
    56941 tccttcaact ggtaatgcga ttcctcgaat atccgatcca ttttgcagcg ctttcatatc
    57001 tttcatataa aagtcctcct catttattcc ctcatttttt ccagcttttc tgcaaatcgc
    57061 tgtgcttctt cttctgagcg gcaaataata atgaatgtat ctacaccggc catcgttccg
    57121 acaacttcag ggtaagccac ttcatctagc caattcgtta ccacatcggc accatttcgt
    57181 tcagtcaata cgataaccat gaactgaaca gactggatac gcaaaacctc gcgtctaatt
    57241 gctgtacgca aacgttcttc atttaaagaa acagatggct ggttaaataa tgtatagcgt
    57301 actattttgt tttcattttg actttttact aacttcattt ctcgaatgtc tcgagaaatc
    57361 gttgcttgag tcacatcggc gcctgcttca tgcagccgcg caagcagctc ttcctgtgtc
    57421 ccaataggtt gttctgtaat gatctggcgg atcagtgctt gtcgctgttt ctttttcata
    57481 ttagacacct ctcaatgttg attatagcaa aagataagta atatttcttc atattttggt
    57541 attttttact tttatttttt gttttcattc aggttgctaa cctttttcta ttttaacacg
    57601 caaaatcgtc ttcatttttt caggtgctga ttttcttgga tcgctgatgt aaatctcttt
    57661 gtgttcttta gaagctcttt catagccttc ttttgcgatg aatgcttcta atttctcaaa
    57721 cgttgctggt tcttcggcat agggcccgac gtgtaagatt tgggcacaaa gaccttcttc
    57781 catctttttg aatactactt gttctttcaa gtcttccgga agtttgctag aacgctgaat
    57841 ggcttcttgt gctatcgctt ctgtaacaaa gtcaggctgt cggatcatca attgataaga
    57901 aaaatgttct tttttcatca ctggttcatg caaatacttt tcttgcagtc cccattgtcc
    57961 ttccagtgga tagacagtat acatctgata atcaggaatc agccaatttt ttttaggcga
    58021 catgcgtatt gcatagctga ctgcatatag acaggctact cttcgtttaa agtcttcctg
    58081 attcgggtcg ccgatccctc tgatgctaaa gaatgatttt ttaggaacct ctagtatttg
    58141 cgggcttttt ttcatactat agctcttgtc tttacgccat tcaatttttt ccatttttct
    58201 tcctccgcga aattccattt agttatttat tatcatacct ctttttgagt gacttggcta
    58261 atcgtgttga cactattttt cagtttgtgc tagaataagt gaagtaaata aatcgtacag
    58321 ataacacgtt tcggcgtgtc gagagagagg cggtttctat ttttataata gaaatcactc
    58381 tcttttttta cgaaattttt tagaggtgat gtaaatgaca aaacaaaaac agctgctttt
    58441 agtacctgca gtaattgcaa cagggatgat gtcttttgcg ggcgtattga tcgagacggc
    58501 catgaatgta actttcccaa ctcttatcag acagtttgat ttaacgactg cacaagtcca
    58561 atgggtaaca acgatttatc ttttgatgat ttcgatcatt gttccgctgt ctacttattt
    58621 gaatcgcaat tttagtctca aaaaactctt tttagcttca aatctgcttt tcttggcagg
    58681 tataatgatc gatttcttct ctcctacctt catggtccta ttgtttggtc gattgctcca
    58741 aggtgcagcg acaggtatcg ctcttccgtt gatgttccat attatcttga catttgcccc
    58801 cctcaatcga cgaggcgcga tgatgggtgt cggtactttg acaacggcca ttgctccagc
    58861 aattggcccc acttatggag gcattatgac ttcacatttt acatggaatc atatcttcct
    58921 gtttcttgtg cccgttttga ttctttcttt gattatcggc tggtttgcta ttcccgagat
    58981 ggcagtacaa aaaagtggtt atttggattg gataagcgtt ttaggaattt gtcttttgtt
    59041 tagtggaagt ctaacatttt tgagtacgtt gggaacagtt tccagctgga ttgctttaat
    59101 catcggcggt attggctggt tcctttttta ctatcgaagt aaaaaagtgg agcatccact
    59161 gatccgactg tctattcttt caaataaaac attccgcttg tttttgattg gcttcttagt
    59221 ttatcagttt ttattacttg gtgtatcttt tgtcttgccg aatttccttc agatcgttca
    59281 aggaagtagt ccttttgtcg ctggattagc gatgcttccc ggcgcagcgg ttggtgcttt
    59341 gctttctcct ttttccggga aaatgctgga tcaatatggt ccgaagaagc caatttttgc
    59401 tgggctgatt ctttctttga ttggttggct agcattattc ctactcatag gacacgcttc
    59461 agtgggtgta ttgattgctt gtcatgtgtt ttatatgatc ggtatcggat tatcttacag
    59521 caatatgatg accaccggaa tgaatgcact gaatgaagaa ctacaaggag acgggaacgc
    59581 aatgttcaat accttgcagc agttttctgg cgctgtggct acttcattag tagcggtcat
    59641 tatcaattac gtccagcatc atacttccca taactatgaa gtgtctacta cattaggatc
    59701 aaaagcagca ttaggcgtct tgttgctgtt gcttctcgta agctttgctc gattcgccta
    59761 ttatctgttc tttgctaaaa aagcgtagat tccatatacg gcaggtgttg catctgccgt
    59821 ttttttgtgt gaaaatggtt gtttgtaaaa ggaggctttt ttatggaaaa aattgccatt
    59881 atcggtggcg ggatcattgg tatgacccta gccagttact tagatacatc aaaattcaat
    59941 gttgctttat ttgatgaagg gacaggacag gcaactaaag ctagcgctgg gattatctcc
    60001 ccttggttgt cgaaacgcag aaacaaacaa tggtatcgtc tggctaaaga cggcgctgct
    60061 tttttcccta aacttataaa agatttccaa cttgatcaaa cgatttacgc acaatcaggg
    60121 acacttttgc ttcgacctga aaaagattta gctgaattgg ctgttcttgc cgagaaacga
    60181 aaagaagaag cgccagaaat tggaaacatc gaatggcttt cacctgaaca gacatctcaa
    60241 gcacttccgt tattgaaacc agcagtttca ctgcgtatca gtggtggtgg tcgtctggat
    60301 ggaaaagcat atttagaaca tcttggtcag cgtttagcac aaaaacaaat ggagcagatc
    60361 caggcaaaag tcactttgca taagaagagc gattcttggc tcatcaaggg accgtttgga
    60421 gaatacacag ctgatcgtgt aattttgaca cctggcccgg cacttaagcc tttattacaa
    60481 gaattaggct atgctgcaga tatacgtccg caaaaagggc agctcttagc atttcagaca
    60541 tcttataaga tgagtcaaga ctggcctgtt gctatgcttg acggagaagc tgatttcatt
    60601 cctttcatgg atggaaagat ccttttaggt gctacccatg aaaacgatca aggctgggat
    60661 ttggctccta ctagcgaagc ttataaggga ttgactaaga gtacagaaca gttcttgact
    60721 gatccagatc agataaaaaa ctggccatac gagttccgtg taggtacccg tgcttatacg
    60781 tcagattttt ccccattttt cggcgtactg ccagatgatc caagcttact ggctgctagc
    60841 ggtctaggct cttctggctt gaccacaggt ccttatatcg gctatctatt agccaacttc
    60901 ttaaatactg gtcattggcc tacggaagat tatcaaaagg acatctccac ctatattacg
    60961 aaaaatccat catagaaaaa cagctttttc aagtaaggat cccgagcgat attgcgcatg
    61021 gattacttct tgaaaaagct gttattttag ttcaatttct gaatcaaatt ctccaaactt
    61081 tcttttgctt catctggcaa gagatctttt cctatctgag cttcaatgaa tcgtaaacga
    61141 atatcaagtc gttgtttcac cagattttta taggacgtat cctcaaaaga aacaggaaaa
    61201 tctggtatag gtaaatagtg gatgtcttca aatggaccaa acgacttgaa ttctgccgtt
    61261 tgttgcacga ttctttcaac gattgacaat gtcgtttcag gtttgatttt tttatcatcg
    61321 aaatatccag tattcaggac atagcaggct gtttgctgtt tcaaaaacaa ctctcgaaaa
    61381 gcttgatagt cttccctaag aggatagaca cggaaaggat tagcaaatgg ttcaatgact
    61441 agctcatcta gctgtctttt tgtagtgata ttttccgcgt ctgatcgttt tgttgctaat
    61501 gttgcaccaa aagacgctgc taaaactggg tcattgatct tgataattgg cggaagcgaa
    61561 tcatctttca tgatccaaaa aacagcatcg atcttttcgc taagatgatc gactcggtcg
    61621 ggtgtcgcat aacgtgattt gactgtccgc ccatttccgt ttcgtatatc tcctgttact
    61681 aggacttttt ctcctttact tgtacatgtc acgcccacat tctgacaagt aaggaaagaa
    61741 gaaatggccg gatcatcaga cggatagtct tgtgttttat caaagtaaga aggttccaag
    61801 gcagtagcaa aaccattttt tcgagaaata acgaaagcat cgtcatgcaa gatcgaaaca
    61861 gagtgacctt ccgtatgttt tgctaaggta atcgttgatt ttccagaacc ggacaaccca
    61921 aatacagcca tcgtataggt ctggtcatta ctagcatatt gtttcatccc accgtggcag
    61981 gcaataaagc cattgcgatt tcccaatgcc caagcaagcg tcaaagtcgc tttttttaat
    62041 tctccaaagt aacgtaatcc tagcacaacc gctgtattat ggagagcatc aaacaaaatg
    62101 agtccatttg gaaatgtttc atgtgtccat tcgggatcac aaaagatata aagatctccc
    62161 tcatcaaagg aaacagactt ttgataagtc tctaagatct tcgaattcgc tggctgaaaa
    62221 ttcagcaaat aagaatacaa attgttctca aatccttctg gaatcagcaa atgactttgc
    62281 acagaaaatt cttcagatag gccaacgatt acttttgtat ggtaaaactg gcgcttgcga
    62341 ctttgataca cagcttctct taaaattttc tcgtatttgc tttgttcctt gtctaagtcc
    62401 tcaaagatcc gccgagcact tgctgttctt cccacaatgc ttccatcatt gaatactagt
    62461 gtcctaacat cagctggtaa atctagttct tcagcatgtg agattgttaa atctgtgatg
    62521 atcgttcctg gactcccttt tgctagttga taagctgtct tcctatcaaa aacttcatga
    62581 acattattac cgtaaaatgt cgtttctaca atcgatcgaa tactggataa cagtggattt
    62641 ccacttgtga tttcgtttaa ttcgagactc tcttttgtac tcatggctcc tcctcattcc
    62701 ctaaacaaaa aaacgttttc tttattatac attattcgag tttttatttg tactgctgcg
    62761 ctgtgggaag caaacgagtt atttttcaca caaaaaaacc gagaacttga ataaacaagt
    62821 ttctcggttt catcattttc cttttatcgg cttagtacca gccgtttgct aaccagaatg
    62881 ttttagcagc atcccatgaa ccataacgag atgttacata ttgttctgct acacgttctt
    62941 gattggcagc tgaatagtcg ccgtttaagt atgaagcatc taattgataa cggccgatgt
    63001 aacgtccgtt agtagctgtg tatgaaccgc ctgattcttt ttgtgcgatc cattcttttg
    63061 cagagcttga agttggcgct gttgcagcag ctggggcagc aggagctact tcaactgttt
    63121 caacaggtgc aacgtatgta tgttcttgcg ttgctgtttc agttgtagat gctgtatttt
    63181 ctgttgtttt gttttctgtt gttgctgaag aatcatttga agttgggatt gttaattgtt
    63241 caccaacata aatgcggttg atgtttgcga tcgaattttt ttcagcaatt gcatcgatca
    63301 ttgagttgtc tcctgcaaat ttttgtgaga tcttagataa tgaatcacct gattttactg
    63361 tataaacttc atcagcgtga gcatttgtag ttcctacaaa cattgcagta gcaccagcag
    63421 caaaagttgt acctaaaaca attttcttaa atgaattcat attaaactcc tttttttctc
    63481 cgttttttat tctttcgacg ctattaactt tatcatttag aaatatttca taggtaaaag
    63541 aaacatgaca tttaatgaca aaataacgaa ttatttaata tttgtaacat ttaaacaaat
    63601 atttttttga tacaaaacca taaaagcctt gttgtataag caaagtaatc gtttttctat
    63661 gtttttttta tttttgaatg aaaaacgcag attctgtaac attcactgca ataatccata
    63721 aaaaaaagca aaaaaatttt tgatttttat caaattctct taaaaaaatg taaaaaatac
    63781 aaaaaaacca gtaattgtta caacaattac tggacaaaaa ctttgaataa tgttaactat
    63841 ttttttattt taactttctc cgcaataatt tctgggcatg ttccaattcg tttataacga
    63901 cttcttctgt ttctttagct aatatttcat ctaatacatc aagccatttt tccggttctt
    63961 ttgttcctag acgtccaata gcccaagctg ctgttcctct gatgacaggg cggacatctg
    64021 ttaaacattc tgaaatctca ggcaatgccg ttcgatcacc tagattagct aaagcaatca
    64081 atgcgtttct ctgcaaaggt ttcttcccac gccatgaacc agctaaatgc ccaaattgct
    64141 gtttgaagtc tttattagac atcgaaagca ttggctttaa ttttggatat atttcgtcta
    64201 cttttggttc catctcttca tgaaaatgaa aatcttttcc ttgattgtaa gggcagacta
    64261 actggcagat atcacatcca taaatgacat ttcgcatttt tttacgatat tcttccggca
    64321 tcatcccttt tgtctgagtt tgataagaca aacatcgctg ggcattcatt cttccgtcac
    64381 caagcaatgc ttttgtcgga caagcagtca cgcagcgcat acagtcaccg caaccaaatt
    64441 ctcctggttt atcaggctca aatacaatat tagtaacgat ctcaccaaga tagacaaatg
    64501 aaccgaactc ttcagtgatc aacaatccgt ttcgtccaat aaatcctaaa ccagctcgct
    64561 gtgctacagc gacatcgatc agttctccag tatctacttg cggagctaga cgccattcct
    64621 cttctttttg ccatttttct gctcttgttt ggatgaattc gatcaatcgg ttcaaacggt
    64681 ctctgagtat atcatggtaa tcgatccccc aagaagcacg agcaaactgc ccgcgttttt
    64741 catccctagg cacttcttca tggatcctag taggatacgc aagtgcaatg gaaatgatcg
    64801 atttcggctg atcaaatgtc atttctggat aaagacgctc atcgatattt ggatgttcaa
    64861 agccagaagt atggccagct gctttttgtt cttccaacga ttcttttaat gaatcaaaag
    64921 gttccgccgt ggtgaacccg attttgtcaa ttcctaatcg tttgctttct tgtatgattt
    64981 cttcttttaa tgtcatggtc ttcctcgctt gctgttaacg gctgtataac ccataatata
    65041 gtttttcttt tttcagctgg acaaactgga tctgctgatc ggcattcttc ttttcttcca
    65101 tccatttttt tcttgcagca aatacttccc aataatttgt tgaaattaat tttcttttgt
    65161 tatctaatgc attaaaaaaa ttcaatgaaa ctggttttgt acttaacagt tcatggagcc
    65221 ttacctcttc ccatggcgaa aactcagaca gatcgcggga atacaatact tcttcataga
    65281 gatttttttg ctgtgtgtac gtgaatgttt gcgggatttt cccaggccta gcaatttcta
    65341 ctagacgatt ataaaacata ttcattaatt tgctgttggc aataaattga cttttataat
    65401 aggccgactg gatctttttg attactcctt ctgctttgat gactgaaaat aatgcaggcc
    65461 atgctttgac ggttatttcg tcgttttgtt taactaatac gccaggtgtg aagccgactg
    65521 gagaaaggaa cacaaaataa ccgataccgg tattttcatc taaaggctga aattcatcaa
    65581 acaaccattt gcctatgtac agctcttcat ctggttctgt tgtctcattt tgatttgcta
    65641 tgaataattt agctaattct gcttcaagaa attgaaggtc ttgatccttg tcggtatttt
    65701 cctgctggct gatcaatcga aagacttctt ctttaatcgt atatttatct ttacgtgtaa
    65761 aattcatagc cacaccttcc ttccttactc taactataac ggaatttctt caaaaaaggt
    65821 atctgtacga cgaaaaacag cataattttt tttcatatct cttataaaaa atgcaaggtc
    65881 tgctcctcaa gctagacctt gcacttttca gctttctttt gtttgtgaca aaccttcatg
    65941 gatcgtttca atattccatt tcatcatctg atagtaagaa tctccttgtt ctccttcttt
    66001 tgctatggaa tcagtgaaca gtttatcata gattttcaaa cccgtttctt ttgctacccg
    66061 ttccatgctt cttgagtcta cactggtttc cacgaataaa accggtactt cttttgctct
    66121 tatctgatca atgatcgctt tcatttgatc aggcgtacct tgactttctg tattgatctc
    66181 ccatatataa gctgctggca aatcatatgc tcgtgaaaaa tacttgaatg ccccttcact
    66241 tgttactaat aattttttgt tctcttcgat agaagcaaaa ctttccttcg cttgtgtatc
    66301 taattctttt agtttttcca catatgcttc tgcatttttt ttatagagtg tcgcattttc
    66361 tgcatctttt tcagagaata tacgtgcgat ttcctccaca tattttattc cgttagatag
    66421 gtctagccaa gcatggggat ctgcttttgt atgttcttca ccgctagtta aataaagagg
    66481 ttctacattt ttgctaactg caaaataatc ttttccttct tcttttttag ccgtttccat
    66541 caagttatcg aaccagctgt tacctgtttc aagattcaaa ccgttgtata aaataacatc
    66601 tgcatcgctt gcctttttga tgtcttctgg tagtacttca tattcatgcg gatctgttcc
    66661 gactggtacg atactgtgga tatctatttg atctgttccg acctcttttg ccatgtccgc
    66721 caagatcgaa ttggtagcca cgactgacaa cttttcttta cttccttcat ccgcttggtc
    66781 agaagcctgc tttccgcaac cggctaatac caagaaacta actgccaaga ttaaaaagag
    66841 tgattttttt gttttcatct atctgcttcc tttctgaaat aaaattcctt ttgttggaga
    66901 aaataaaaaa gcaaggataa aaaatgcggt acatgctaac acgatcgtag ctcctgatgg
    66961 ccaattgtaa ctataactga aaaacacacc gacaactgca cttagcatac cgattcctgc
    67021 agctgtaatg atcattttca gtaaatggtt cgttagcaag taagccgtgg cggctggtgt
    67081 gatcaacatg gcaatcacca agattgttcc tactgtctgt aaactgacta cagccactaa
    67141 tgtcaaaaag aacatcaaaa gataatggat cagcgatgtg ttcagcccat aagcttttgc
    67201 cattgtcgga tcgaatgatg tgatcttcaa ttctttataa aagaaaaaga caaatatcaa
    67261 gacgattcca ctaacgagtg ctgtcagcaa caaatcgctt tccctaacag ctaagacatt
    67321 cccaaataaa atatgataca aatctgtcgc actctgggca tatgaaatca agataatccc
    67381 taatgcaaaa aaggagctaa agacaattcc aatcgctgta tcatttttca atcggctccg
    67441 ctgagtcacg aaaccaatca ctgctgctgt tagcatccca aaagcagtgg ctccaaagat
    67501 gtaactaaaa ccaaacatat aagaaatggc tacacctgga agaactgcgt gagagatagc
    67561 gtctcccatc aaagacatcc ctcgtaaaat aataaaagaa ccgatgactc cagaagcaag
    67621 tcctacaagc atggaagtga ccaaagcgta ttgcaggaat tgataattca ttaatccatc
    67681 aataaaggat tggatcattt tttctctcct ccttttacta aatgtctgat gatctcacca
    67741 taggccaatt gaaggttctt cgatgtaaag acttcttgta ctggaccgga agcgatcagc
    67801 tgtttattta aaagaataac ctcatcgaaa tattcttcta ctttatgaag atcatgatgg
    67861 acgatcaaaa tcgtttttcc tgaattcttc aattcctgca agatgtcaaa gatctttcgt
    67921 tcacttaacg catcaatccc tacgaatggt tcatctaaaa agatccattc tgctccttgg
    67981 gctagagctc ttgcaataaa aactctctga agctgtccac ccgatagttc gctgatctgt
    68041 cttttggcat attcttccat ccctactttt ttcaaagctt gtcttgcacg ttctttttct
    68101 tttttcccag gtctttgtcc aattcgtaaa gatggatatg ttcctaaaag tacaacgcct
    68161 aatacatcaa ttggaaagga aagatccaat tcacttcgct gttccacgta ggctattttt
    68221 ttacggactg agtttaccga ctgtccagaa aaggtgactt taccagtagt agctggtatc
    68281 aactctagca aagatttcat aaatgttgat tttcctgcac cgtttggtcc gataataccg
    68341 gtaatttttt gtggatttat cgtcaagttg atagttttca aaacagtttt cccttgataa
    68401 gcggctgaaa ggtcttgaat tacaatggcc gtacgttcca aatcttacac tcctttttag
    68461 gtttacctaa ctttttattt aaatatagtt taactaaaat ggaaagcatt ttcaagtaga
    68521 atgatgaaaa agtttttttc gaattttcct cgcattttat gaaaattttc tgtagaatca
    68581 catcaagagt tcaataaggc taacctaata atgaaaaaca tgtgttgaaa cgtttgatta
    68641 ttttttcttg ttgactcaac aacgaaagga gtttttgtat ggaagaagaa aagttaactc
    68701 gaagtcttag tgcccgtcat atccaaatga tcgcactagg tggaacgatc ggtgtcggtc
    68761 tgtttatggg tgcctcctca accatacgtt ggacagggcc ctcagtgatg ggagcctatg
    68821 cgattgcagg attctttttg tatttgatta tgcgtgcttt aggcgaaatg ctttacgttg
    68881 atccttcgac tggttctttt gcaaattacg cgagcgagta catccatcct gtggctggct
    68941 acttgaccgc ttggagtaat atttttcaat atattgtcgt aggaataagt gaagtgattg
    69001 ctgtaggatc ttatatgaat tattggtggc ctgatttgcc ggcaattatt cccggaatca
    69061 ttgtcgtctt gtttcttatg ctggcaaatc ttatttctgt caaggcgttt ggcgaattag
    69121 aattttggtt ttcgatcatc aaagtcataa cgatcatttt gatgatcatt gcaggtcttg
    69181 gggtaatctt atttggattt ggtaatcatg gtcaggcagt agggatttca aatctttgga
    69241 aaaatggtgg attcttcact ggaggcgtca aaggattttt ctttgcatta tcgatcgttg
    69301 ttgcttccta tcaaggaatc gaactgatcg gaatgactgc tggtgaagca gagaatccta
    69361 aaaagacgat cattgaagct gtccagtcca ctatcggtcg aatcttgatt ttttatattg
    69421 gtgctatttt tatcattgtg agtatctatc cgtggaatca attgagtgag attggttcac
    69481 cttttgtaca aactttttct aaagtcggca ttacatttgc tgcaggactg attaattttg
    69541 tcgtgattac agcggcatta tcaggttgca attcagggat tttcagcgca agtcgtatgg
    69601 tctatacact tgccataaat ggaaagatgt ctaaaaaatt tctgaaacta tctcgtcacg
    69661 gtgcgccttt ttatcctgtc gtagcaatct caggtggaat cttaattggt ctgatcttaa
    69721 attatcttct accaatgttc atcaaccagt cagaaaatat tttcgttttc gtatacagct
    69781 caagtatttt gcctggtatg gttccttggg tagtgatttt gatcagcgag attcgcttca
    69841 aaaagaagca cgcagataaa atgcatgatc atccttttaa aatgccacta tctccttata
    69901 cgaattatgt gacacttgct tttttagcta tcgtattgat tttcatgttt atcaatcctg
    69961 aaacgagaat ctcattgatt attggactcg ttttcttgct ttacatgacg atccattact
    70021 ttgtacgcga aaaaagaacc ggaaaataaa aaaagaacga agcttcacct tagtggaagc
    70081 ttcgttcttt tttattgctt ttatcaattc aattttagcg tctcaccggg agtcaggaaa
    70141 taattctcca tgctcatccc attcagcgac aagatcgttt ctactggtac gccagttcgt
    70201 tcggctattt gatttggacc ttctccttcc aaaactacgg ttgtcgcagc ctgtgaagtc
    70261 gcgctgttgg tattagtttc agaggaatct gttgtgtctt gtgttgttcg agcttgcatt
    70321 tcagaagctt ctaccgactc tgctgtctca gaatcagaag atgttgtgtc ttgtgtgctt
    70381 gttgactctg cttgaagaga ggcgctagtc tgcaaataaa tatcggaaat cttagcgaca
    70441 tgattcgtat aattagccga taattgattg atcaaagtat ctaagtctac accgtcttta
    70501 ttttctgctg cctgatacgc tgcacgtaat tttctgatcc cttcgtcgga gattgcttga
    70561 agctcacgtg ctttttggtt agcaactgct gataaaccag ctattccctc ttgatttccc
    70621 tgaatttctg tctggtattc ttcaatcaat gcaggcgtct tttcttcgat ctttttcgaa
    70681 taatcattta cgattgcttg aagttgctct ggcaaaccat ttgctgtttt ttcttcagaa
    70741 gtttgtgtct cttttgtttt agttgatgac tcacttgttt gtttcgtctc tgttttcttt
    70801 gtcgttgttt ccgttatggt cgtacttttc gcttctgacg aattttttcc atgaaaatat
    70861 agacccgcaa ctcctcctgc tatgatcaaa aacacggcaa ctgctgcccc aatcatgatc
    70921 atccgcttac gagctgcctg tttttgctgt cttcttcggg tcatccgaac attttctccc
    70981 cactcatttt catcatacat ttttttcacc accaattttt atgtataata gcgttatcaa
    71041 acgcttcata ttcttattgt agcaaataat tgtcgctgtg cacattttta tctttgttat
    71101 ttataagaaa atttcaccag ttgagatgat tccaagattg tccgtcgatt tctccttgca
    71161 gctgcattgt tcgttcgtct atctcagcca tcagtttctt tatttcatat aagagcgcac
    71221 ggtcttgata ttctgatttt tcgcttaatt catctaattg ttggatcagc caatcatttg
    71281 tcataatgaa gttcctttca tttcttgcag tgtaaaggtc aagtcttcga tctgctcttt
    71341 tgcctcagtc agtgcttcta cgatatatgc ttgtttttca gattcttctt cctgcatttt
    71401 ctgattttcc tgtactcttt gaataaacca gtcaatccgc tgagtcagcg atggtttgcc
    71461 ttccaatgag agatactgct gataagcaat tagcttctcc caacgttttt cctgggataa
    71521 atacataaat tgtgctaaaa cgaatggcgg aagataggtc atatggaatt tatttgcgat
    71581 tcgctgatac ggcctcaaaa attcggaaat cgtatattct tcttttcctc cagcttggta
    71641 ttctttttcc gccacacctg ttgtcaatac gattcctagt tctttccctt ttaatacatg
    71701 tgctgctcgt tccaagacat tatcttgcca aatttttaaa tgagcaggag aactatacca
    71761 gtaaaacgga aactggaaaa tgatccgatc atgctgggcc aagagctgta gttcagtctc
    71821 tatatctatt tttccgtctg gataacttga ttccaaatga tgccaagtag ctggtaaacc
    71881 agcagaagct tctttgaaaa attgctgatt taaagattct tcgatcgttg gatggctaat
    71941 gatgataagt gtacgcatcc cttttcctcc tttttagtct tcgctttaca gtgtagcata
    72001 accgccacaa gtttcttttg ccgatgcttg tcattttaac cagactaatc aggttgtcca
    72061 agaaactgtg gtttgttttt ccaactgttt tttcaaggta tccaaagcaa tattcttaaa
    72121 atttttgttt ttcatacgtt tacgatagtt cgtagccgtt tctccggtac tctttttgaa
    72181 cattcggcta aatacgacta gactattgaa ccctacttga taggcaatac tttccacgga
    72241 ttcatccgtc agagaaagaa gaaacgcccc tcgattgatc cgtaccccga tcaaatattc
    72301 cttgatactg gtacccatat gatttttgaa tactcgcgac aaatggctcc gattgaccgc
    72361 taaatgctgg gcgatttcct caacagacaa tttttcagca taatgtgcct cgatgtattt
    72421 gactgtttca acagctaaag aggaatgaac cttttgtaca ccaccgctga cctttccgcc
    72481 atcttttaaa aggactgata aaaaacggta ggttaatgct gttaactgta attcattttc
    72541 caaggtttct tccgtatctt tcatgcattc taaaataatg tcgatatatt tttgtatgtc
    72601 agaagagacc atcgtgtatt ggtcttctct gaaaagcgac tgccgaatga tttcttctgc
    72661 agcactccca ccaaatgaaa gccagcaata catccacgga tcttctccat ctgataagta
    72721 aaacgtcgag tctcctggac gaatcaagaa cagatcacct tttttcaatt ggaattgttg
    72781 atttttcaca tgataagatc ctttgccttc catcacgaca tgcaggatgt aatcattgcg
    72841 aatagcagga ccaaaagaat gaaacggcat cgttttagag aaaccacaaa aatcaaaata
    72901 caattctttt tctacttgtt gatgttcctt ttttaaaaaa atcgattgct ccacgtctat
    72961 ccctccttac tcctttagta taatgcaaca aaaagttaaa taaaagtcac agaaatatat
    73021 taaaaaggaa gcgatttctt gttaagttta agtcattaaa agatctttgt tattcgttgt
    73081 aaccggttta cttagtatta tatattgaac aggagaggaa tacagattat gaaaagcaaa
    73141 atgatccaac gtgtgtccta cgctttaggc gcttttggac acgacacatt ctatgttaca
    73201 ttaagcactt attttatggt attcgtgaca agccagatgt tcgcaggaac agataaggca
    73261 acgaatgcaa aaatgattgc tacagttaca agcttagttg taggtatccg cttagttgaa
    73321 attatttttg atcctttgat tggtggcatc atcgataata ctcgtacaaa atacggtaaa
    73381 ttcaaaccat ggttagttat cggcggcgtt gttagttccg tactcttggt agcaatcttt
    73441 accaatttct ttggcttagc tactcataat acgactttat ttatcatatt atttgcaatc
    73501 gttttcatct tattggatag tttttattca tttaaggata tcgctttttg gtcaatgatt
    73561 ccagctttga gtacggaaac aaaggaacgt gaaaaatttg ctacgtttgc tcgtttcggc
    73621 tcttctctag gtgcaaatgg tactactcta gtcgttgtcc ctatcgttac tttctttacc
    73681 tatcttgtta ctcataaaca tattgaaggc gcttcaggct ggttctggtt cggtgtgatt
    73741 gctgctgtta tttcaggcgg tactgcgatt atcactgcct tgggcacaaa agaagtcgat
    73801 actgcgatcc gtcagcaaaa tgaaaaagct gggatcaaag atgtgttcaa agcagttgct
    73861 caaaatgatc agttgatgtg gcttgccctt gcttatatcg cttatgcgat tgccaatgca
    73921 gcaacaactg ccgtattatt ctacttcttc aaatatgtac ttggccaacc aactgaattt
    73981 tggatcgttg gtctagttgc tgccttactt ggtttagtag ctgttccact attcccaatg
    74041 cttacacgcg tcatctctcg tcgctacgtt taccttggag ggatcgcaat gatgatttct
    74101 tcttactttt tctttacgat cgcaggttca agtttgccaa tcgttatcat cgggctagta
    74161 ttgttctact tccctcaaca attgattttc ttatccgctt tgatgacgat cacagactct
    74221 gttgaatatg gtcaatggaa aaatggtatc cgtaacgaag ctgttactct atcaattcgc
    74281 cctttactag ataaaatcgc tggtgctttg tctaacggga tcgtagggtt tgtcgctatc
    74341 gcttctggga tgactggtaa tgctactgct gctgatatca ctgctcatgg cgtaacgact
    74401 ttcaaagctt atgcattcta tgctcctgct gctttgatga ttttctccgc tattattttt
    74461 gcttggaaga ttacattgac agagaaaaaa catgcacaaa tcgttgagaa attggaaaac
    74521 aaattggctc cagctgatac aatggaagat gaacttcacg atgcagtaga tccttcccat
    74581 taagaaagga tcttgaaaat gaagattaca gaaaaagatt ttggccaagg ttatcacttg
    74641 ataaccttgg agaacaaaaa caagctagca ctttctatct ctgatttagg tgctagaatc
    74701 gtcagtttaa aatcaaatga tcgagaatta gttttgggat ttgacaccgc tgaagaatat
    74761 atcgaaaaag atccgtatat cggtgcttct atcggtcgca ccgcagggag aatcgaaaat
    74821 ggccactttt ctctcaatgg aaaaacttac caattagcca cagatccaaa aactggacat
    74881 aatctgcatg gtggtgctcc tggatttgaa ttaaaaaaat ggtcttatgt cattttgaat
    74941 ggcgaaaatg aagcttctgt catttttact actacaagtc ccgacggaga acatggtttt
    75001 ccaggtacaa tggatgtgga aatccgctat actttgacaa aagataatat ctggcgagtg
    75061 acctctcgcg gcaccagtga ccaagatact ttattcaatc cgacaaatca tgtttacttc
    75121 aacttgacgg gagatgcttc tcagtcaatc gatcaacatg agctttggct caatagcgaa
    75181 gcttatgctc ctttgcgaac agatagtatt cctatagggg taaaagaaaa tgctgcagga
    75241 agtgctttcg attttcaaat acctaaaaaa ttagcgtccg tttttgctag tgatttggat
    75301 caaaaaaatc ttgttgacgg aatcgatcat ccatttttct taaaagaaac cggcttgggt
    75361 aaagaagccg ctcgcttgac tagccccgat aaaagaatcc aagtagatat tgctacagat
    75421 gcttctagtg tggttatttt cactgcaaat ttcggcacag aaacaccaga aatgcgcaac
    75481 cgaaaactgg cacatcacgg tggcatcaca tttgagactc aaacagctcc aggtgcagag
    75541 cgcttctcag catttggttc gattcattta aaagccggat cagtatttga aacagtgaca
    75601 gaattcaaaa tcaaaacaag aaaggaataa ctcatcatgg aaatcaaaag aagcttaaac
    75661 acaaaatttg ccgaaacatt cggacctaaa aaaactacac aatacttctc accaggacgc
    75721 atcaatttga ttggtgaaca cacagattac aatggaggcc atgtcttccc cgcttccatc
    75781 acttatggaa cgcaaggtgt agcagcacct cgagacgata ataaaatatt agtttattcc
    75841 acaaactttg acgatatcgg tgtcattagt tttactttag atgagctaga atatgataaa
    75901 aaagcaaact gggcaaatta cgtaaaagga atggtcctta aattaaaaga agctggacac
    75961 tcaatcgatc atgggtttga gttattagtg gaaggaacaa tccctaatgg tgcaggactt
    76021 tccagtagcg cttcattaga attattagta ggtgttgtat tagaagatct gtttgattta
    76081 aaaacagatc gcttggaact agtccaaaca ggtaaaaaag tagaaaatga attcatcggt
    76141 gtcaattcag gtatcatgga tcagtttgcc atcggcttcg gtgagctaga tcatgcaatc
    76201 ttattagata caaatacgct gaaatacgaa atggttccag tgaaactaga tggttatgca
    76261 atcgtcatca tgaatacgaa taagcggcgg gaattggcag attcaaaata caatgaacgc
    76321 cgtagcgaat gcgaagaagc cttggcacgt ttgcaaaaaa ctttgcctat ctcttcttta
    76381 ggagacttag atgaagaaga atttgaatca actattgacc aaatcggcga tgatacattg
    76441 atacgcagag ctcgccatgc cgtttctgaa aatcagcgga ctttgaaggc aaaagctgaa
    76501 ttagaagctg ggaacttaga agcatttggt caactgttaa atgattctca ccactctctt
    76561 cgctatgatt atgaagtaac tgggatcgaa ttagatacac tagtagatgc tgctcaaaaa
    76621 caagaaggtg tcttaggtgc acgaatgaca ggagctggat ttggtggctg tgcgattgct
    76681 cttgtcaaag aagaaaatat acctgccttc aaaaacaatg tctatgatga atacatgaaa
    76741 gttgtcggct atgctccgga attttatgtt gcacacattg gaaatgggac aacaaagatc
    76801 gatccagaag ctgttcatgt ttgataaaaa aatcaacgat ctcagctaaa aacaaataga
    76861 taaaaataac ctctcagcaa tttccaaatg tgagcctttt gctcgtattt gaaaattgct
    76921 gttttttatt gacacggaaa gagaacgtgt gttctaattg tgttgaagag gtgattgtta
    76981 tgtgggcgaa tcaaaatccg gtatttgttt atgaaaaaga accttcaaga gatattttat
    77041 gtattgactg caaatctttt tacgcctccg tagagtgcgt tgaaaaggat cttgatcccc
    77101 ttacaactaa attagtagtc atgtcctatc cgtccgattc gacagaaaca cggggtagcg
    77161 gattaatctt ggcttccagt cctgcagcaa aaaaagctta cggcatcacc aatatcagcc
    77221 gtgccagaga tcttcccttc ccctatccaa gtgatttata tattgttgcc ccaaggatgg
    77281 cctattatat ggaaaagaac agagaaatca attctatcta taaaaaatat gcagacgaag
    77341 cgaaccatca tgtctattcc gtcgatgaaa gcttccttga tgtaacaaat agcatggcac
    77401 tctttggtaa aacaaatgcg tacgacatgg ctaaactgat ccataaagat gtgtttgagc
    77461 agaccggaat ctacacgact ataggaattg gcgataaccc gctacttgct aaactagcct
    77521 tagacaatgg ctcaaaagac ggaaagcaaa tgtttgctga atggcgttat gaagatgtac
    77581 cagaaaagtt atggaaaatc tcagatatca ctgacttttg gggaatcggc aaacgaacag
    77641 caaaacgtct gaaacaaatg ggtatacatt ctgtttatga tttagctcac gcggattatt
    77701 atcacttgaa aagcaagcta ggggtcatcg gtactcagct ttatgcccat gcttggggca
    77761 tcgatcgaag ttttttggga caagaatata caccaaaatc aaaaagtatc ggaaatagtc
    77821 aaatcctaga tagagattat acaagacgag aagaaatcga gatcgttatc aaagaaatgg
    77881 ccgaccaagt cggcactcgc ttgagacgat ctgcagcaaa aacacaagta gtcagcttat
    77941 gggtaggata ctctttaggc tatcttgatc caaatggcaa gaccgggttt caccagcaaa
    78001 tgaaaatcga agcgacaaat gctagcagag atctagcaga tgctttattg accattttcc
    78061 accagcatta ccactaccag gatattcggc gtgtaggcgt gaactgttcc gacctcgtat
    78121 acgcgacagg tttacagctt aacctttttg aagatcctga aaagcagata aatgaagcga
    78181 aagttgattt tgttgtcgat acgattagaa aaaaatacgg ctttcaatca atcatccatg
    78241 cgcatagtct cttgcaagga ggacgcgcca tcgcacgtag ttctctcgtt ggcgggcatg
    78301 caggtggtat gagtggatta gaaggtggaa aagatgagac ggacagcaaa aaaattcatt
    78361 gactataacg agtatcgaga tcggccattt ggattaaaat gggggactgc ttttgcgatg
    78421 gaagaactag tcaacggtat caaaaaaaat gaagaagaag cacgcaaaca gcctcttcct
    78481 aaacaacaaa tgacattgca agaaatcgat agtatactga cagaagcctt tttatctcgt
    78541 aaagcagtaa tcattcagct caatttaaaa gatgaatttg gaagactctt ggatgaggtc
    78601 gaagggcact tcattggtga agcctatgaa gattacttta tgattgacca tcagccgata
    78661 ttgtgggaag acgtacggta tattgagtta aaggaaacaa aaaaatggtt tgtgacatga
    78721 gaggttgtga cagaagtgat caacttcaaa aaataagaaa ggatttttcg aaaattgctt
    78781 cttaaatttt tgtggaattt tggcttattt ttcgaagaag caacttctgg aacaacgtat
    78841 attagatatc agaggttgtg aaaaagtcgc ttagttttga gtaacaagcc aaggcgctga
    78901 tttcacaacc tctgtctatc tatccatcta ttcggtaaga ttcatgcatg acgtcttctt
    78961 tatttagtat gtagagccct ttttcttctg accattcaac ataaatcagc tgttttacat
    79021 ctgcatagcc ttctttcttc aagttctcca taagccatgc ttcagtcaat tgattggact
    79081 gaagcacttt atgctgaatt tgcccttcat ctacaagcag gatcgataaa gctttgtctt
    79141 catctgattt tttcaataca ctcatttgac cggcattctc taggataaca tgtttggcat
    79201 tttcaagaaa aaagcattct tgctgtctta agattgctcg caactgctcc atctcgatat
    79261 ggttatttgt caactctgtc atgttgatga cgccgtcttt gattagaaca gatggctcgc
    79321 ctttgaccca acgattgacc ttttcatttt tttggacgat acgttcgata ccataaatca
    79381 ttactgccca aagcgcaatg gcaaatagga catgccctac atggacattg tcatcatagg
    79441 ttgattcttc taagatccca cctaaaacaa gcgtatagac taaatcaaac ggtgtgattt
    79501 ctgacatgga tttcttccca agcaaacgta ccactaataa taaaccgatc aacccgaaca
    79561 ccagtttcat tgtaattgaa aaaatcattt tttctccccc taactatctg ttaattaaat
    79621 tatatatgct ttctcacgaa cacgcatgga atatacaagg aagaaatgta tccttttact
    79681 aaaaaaagga ctgtgacact gtagtgaccc ccaaaagtta gacttttttg gagtggagaa
    79741 atccactcct tttttttatg ctctaaaatg atatttttac acaaccgtta cggttgtttt
    79801 acgaaattgg acg
//
LOCUS       DAFBSV010000004        66417 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.004, whole genome shotgun sequence.
ACCESSION   DAFBSV010000004 DAFBSV010000000
VERSION     DAFBSV010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 66417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66417
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.004"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            85..972
                     /locus_tag="LLB18_000290"
     CDS             85..972
                     /locus_tag="LLB18_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBK5243322.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="LLB18_000291"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="LLB18_000291"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBK5243323.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVHPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="LLB18_000292"
     CDS             2274..2720
                     /locus_tag="LLB18_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBK5243324.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="LLB18_000293"
     CDS             2993..4345
                     /locus_tag="LLB18_000293"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HBK5243325.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="LLB18_000294"
     CDS             4516..4803
                     /locus_tag="LLB18_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243326.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            5029..5472
                     /locus_tag="LLB18_000295"
     CDS             5029..5472
                     /locus_tag="LLB18_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK5243327.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(5478..6662)
                     /locus_tag="LLB18_000296"
     CDS             complement(5478..6662)
                     /locus_tag="LLB18_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HBK5243328.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            6930..7628
                     /locus_tag="LLB18_000297"
     CDS             6930..7628
                     /locus_tag="LLB18_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBK5243329.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            7635..8312
                     /gene="nth"
                     /locus_tag="LLB18_000298"
     CDS             7635..8312
                     /gene="nth"
                     /locus_tag="LLB18_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBK5243330.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(8438..8971)
                     /locus_tag="LLB18_000299"
     CDS             complement(8438..8971)
                     /locus_tag="LLB18_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243331.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(9268..11649)
                     /locus_tag="LLB18_000300"
     CDS             complement(9268..11649)
                     /locus_tag="LLB18_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBK5243332.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(11639..12286)
                     /gene="recU"
                     /locus_tag="LLB18_000301"
     CDS             complement(11639..12286)
                     /gene="recU"
                     /locus_tag="LLB18_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HBK5243333.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            12350..12889
                     /locus_tag="LLB18_000302"
     CDS             12350..12889
                     /locus_tag="LLB18_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HBK5243334.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            12979..13398
                     /gene="gpsB"
                     /locus_tag="LLB18_000303"
     CDS             12979..13398
                     /gene="gpsB"
                     /locus_tag="LLB18_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HBK5243335.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            13420..13787
                     /gene="rnpB"
                     /locus_tag="LLB18_000304"
     ncRNA           13420..13787
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="LLB18_000304"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13996..15162
                     /locus_tag="LLB18_000305"
     CDS             13996..15162
                     /locus_tag="LLB18_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBK5243336.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            15208..16704
                     /locus_tag="LLB18_000306"
     CDS             15208..16704
                     /locus_tag="LLB18_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HBK5243337.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            16785..17468
                     /locus_tag="LLB18_000307"
     CDS             16785..17468
                     /locus_tag="LLB18_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBK5243338.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            18113..19303
                     /locus_tag="LLB18_000308"
     CDS             18113..19303
                     /locus_tag="LLB18_000308"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HBK5243339.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            19405..20358
                     /locus_tag="LLB18_000309"
     CDS             19405..20358
                     /locus_tag="LLB18_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBK5243340.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            20427..21776
                     /locus_tag="LLB18_000310"
     CDS             20427..21776
                     /locus_tag="LLB18_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK5243341.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(21959..22282)
                     /locus_tag="LLB18_000311"
     CDS             complement(21959..22282)
                     /locus_tag="LLB18_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243342.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            22411..23574
                     /locus_tag="LLB18_000312"
     CDS             22411..23574
                     /locus_tag="LLB18_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBK5243343.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            23644..24993
                     /locus_tag="LLB18_000313"
     CDS             23644..24993
                     /locus_tag="LLB18_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBK5243344.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(25038..25469)
                     /locus_tag="LLB18_000314"
     CDS             complement(25038..25469)
                     /locus_tag="LLB18_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5243345.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            25857..28499
                     /gene="alaS"
                     /locus_tag="LLB18_000315"
     CDS             25857..28499
                     /gene="alaS"
                     /locus_tag="LLB18_000315"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBK5243346.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            28699..29295
                     /locus_tag="LLB18_000316"
     CDS             28699..29295
                     /locus_tag="LLB18_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBK5243347.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKKKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            29417..30565
                     /locus_tag="LLB18_000317"
     CDS             29417..30565
                     /locus_tag="LLB18_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBK5243348.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(30603..31016)
                     /locus_tag="LLB18_000318"
     CDS             complement(30603..31016)
                     /locus_tag="LLB18_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HBK5243349.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            31095..31526
                     /locus_tag="LLB18_000319"
     CDS             31095..31526
                     /locus_tag="LLB18_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HBK5243350.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(31625..31858)
                     /locus_tag="LLB18_000320"
     CDS             complement(31625..31858)
                     /locus_tag="LLB18_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HBK5243351.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            32041..33711
                     /locus_tag="LLB18_000321"
     CDS             32041..33711
                     /locus_tag="LLB18_000321"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBK5243352.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            33858..34244
                     /locus_tag="LLB18_000322"
     CDS             33858..34244
                     /locus_tag="LLB18_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243353.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            34231..34929
                     /locus_tag="LLB18_000323"
     CDS             34231..34929
                     /locus_tag="LLB18_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBK5243354.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            34934..35398
                     /locus_tag="LLB18_000324"
     CDS             34934..35398
                     /locus_tag="LLB18_000324"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBK5243355.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            35395..36306
                     /locus_tag="LLB18_000325"
     CDS             35395..36306
                     /locus_tag="LLB18_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBK5243356.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            36541..37080
                     /gene="pyrR"
                     /locus_tag="LLB18_000326"
     CDS             36541..37080
                     /gene="pyrR"
                     /locus_tag="LLB18_000326"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBK5243357.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            37094..38377
                     /locus_tag="LLB18_000327"
     CDS             37094..38377
                     /locus_tag="LLB18_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBK5243358.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            38390..39316
                     /locus_tag="LLB18_000328"
     CDS             38390..39316
                     /locus_tag="LLB18_000328"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HBK5243359.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            39335..40615
                     /locus_tag="LLB18_000329"
     CDS             39335..40615
                     /locus_tag="LLB18_000329"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBK5243360.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            40620..41696
                     /gene="carA"
                     /locus_tag="LLB18_000330"
     CDS             40620..41696
                     /gene="carA"
                     /locus_tag="LLB18_000330"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBK5243361.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            41701..44886
                     /gene="carB"
                     /locus_tag="LLB18_000331"
     CDS             41701..44886
                     /gene="carB"
                     /locus_tag="LLB18_000331"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBK5243362.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            44940..45716
                     /locus_tag="LLB18_000332"
     CDS             44940..45716
                     /locus_tag="LLB18_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBK5243363.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            45713..46645
                     /locus_tag="LLB18_000333"
     CDS             45713..46645
                     /locus_tag="LLB18_000333"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBK5243364.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            46642..47358
                     /gene="pyrF"
                     /locus_tag="LLB18_000334"
     CDS             46642..47358
                     /gene="pyrF"
                     /locus_tag="LLB18_000334"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HBK5243365.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            47365..47994
                     /locus_tag="LLB18_000335"
     CDS             47365..47994
                     /locus_tag="LLB18_000335"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HBK5243366.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            47982..48296
                     /locus_tag="LLB18_000336"
     CDS             47982..48296
                     /locus_tag="LLB18_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243367.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            48334..48975
                     /locus_tag="LLB18_000337"
     CDS             48334..48975
                     /locus_tag="LLB18_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBK5243368.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            49018..49710
                     /locus_tag="LLB18_000338"
     CDS             49018..49710
                     /locus_tag="LLB18_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HBK5243369.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            49707..50609
                     /locus_tag="LLB18_000339"
     CDS             49707..50609
                     /locus_tag="LLB18_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK5243370.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(50767..52473)
                     /gene="efbA"
                     /locus_tag="LLB18_000340"
     CDS             complement(50767..52473)
                     /gene="efbA"
                     /locus_tag="LLB18_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HBK5243371.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            52663..53286
                     /locus_tag="LLB18_000341"
     CDS             52663..53286
                     /locus_tag="LLB18_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243372.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            53736..54785
                     /locus_tag="LLB18_000342"
     CDS             53736..54785
                     /locus_tag="LLB18_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK5243373.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            54782..55663
                     /locus_tag="LLB18_000343"
     CDS             54782..55663
                     /locus_tag="LLB18_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5243374.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            55666..56436
                     /locus_tag="LLB18_000344"
     CDS             55666..56436
                     /locus_tag="LLB18_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK5243375.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            56715..57569
                     /gene="aroE"
                     /locus_tag="LLB18_000345"
     CDS             56715..57569
                     /gene="aroE"
                     /locus_tag="LLB18_000345"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBK5243376.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            57747..58910
                     /locus_tag="LLB18_000346"
     CDS             57747..58910
                     /locus_tag="LLB18_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBK5243377.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGGQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            59027..59437
                     /locus_tag="LLB18_000347"
     CDS             59027..59437
                     /locus_tag="LLB18_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBK5243378.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            59611..61839
                     /gene="topB"
                     /locus_tag="LLB18_000348"
     CDS             59611..61839
                     /gene="topB"
                     /locus_tag="LLB18_000348"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBK5243379.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            62010..62294
                     /locus_tag="LLB18_000349"
     CDS             62010..62294
                     /locus_tag="LLB18_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243380.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            62454..62690
                     /locus_tag="LLB18_000350"
     CDS             62454..62690
                     /locus_tag="LLB18_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBK5243381.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            62687..63085
                     /locus_tag="LLB18_000351"
     CDS             62687..63085
                     /locus_tag="LLB18_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBK5243382.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(63752..64696)
                     /locus_tag="LLB18_000352"
     CDS             complement(63752..64696)
                     /locus_tag="LLB18_000352"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBK5243383.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(64992..65936)
                     /locus_tag="LLB18_000353"
     CDS             complement(64992..65936)
                     /locus_tag="LLB18_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5243384.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            66157..>66417
                     /locus_tag="LLB18_000354"
     CDS             66157..>66417
                     /locus_tag="LLB18_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5243385.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGI"
BASE COUNT        21887 a        11513 c        14031 g        18986 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgcatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga aggaatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt tttcttggtt tcagattggg ttttcctaca aaatattttt atctttgttg
     4981 aataggaaac aaaaaaacaa tataatgaaa gaaaaagaag gtgtagaaat ggataaaaga
     5041 caactgctaa tagaagaata tctggattta gctaatgaga ttattcatcg taataaacca
     5101 gaaatggaaa aagaatttgc aggatttact ctaaatgaac tagaagtgat tgaacatatc
     5161 gggaaaatcc ctgatcctaa cgtgacaaaa ttagcgaatg ctagttacat gactagagga
     5221 gccatcagta agctaacaaa aaaactgata gctagaggga tcataaacac ttatcaaagc
     5281 gaagagaata aaaaagaaat ctattttcaa ttgacgccaa tcggacaaaa aataaggaat
     5341 agacacgagc aactccatca aaaatgggta cagcgagatg ctactgtatt tgaaaatatg
     5401 tcaaaagaag aatttgacac agtatttcgt tttatcggtc gatacagaga atttatacga
     5461 agtagcaaat gaagctacta ttttttattg tagtgataat aggcaaaaat cataagcaaa
     5521 aatccgaata ccgtcggaag aaatggtgct gcagcataaa gctgtcctgc gattagcggg
     5581 ccgatgacgc gcgatagaga ttgtatactt tgggtaccgc ccattacaag accttgctgg
     5641 ttatctgaga cagaattgga tagttggcca ttgaatacag gagtaaaaat agaatcaccg
     5701 aaaccataac agataatccc aaataaaaac aaaatcggca gtagaagaat tccagataat
     5761 gtgatgaata gataggcgag gatttcactg aacatcccta ttcttgtgat ctgctgttct
     5821 gaaaattttt tgagcaatcg aggcataatg aacaattgcg agacagtatc caagattcca
     5881 atcaaagaga agcttaaacc aaccaaccca gccttccact gaaaggcgtc aatcgaaaat
     5941 tgagaaaaga tagattgaag agagccagct gccaaccaaa cagcaaaacc tgctgtcaat
     6001 aaaggaataa cggatgaaat cttgaataat tgttgtaatt ggtgaaaagg tcttacatgg
     6061 gagaaactta aatctactga acgttttttt attggaaggc tttctagcat aaatgtgtag
     6121 ccataaacgg catttaagaa agtaaagagt gctccaataa atataggaac agaattcccc
     6181 aactcagcta atagaccccc tataatagga cccagcgttg ttcctatacc gactaaagca
     6241 cccatccatc caaaaacttt ggttctttca ttaggttccg tgatgtcggc aaagtaagca
     6301 tataaggtgg agatttctcc tgccgtcaat ccttcaatga tacgaccaag gaacaacatc
     6361 catatcgaat ttcctaaacc aaaaagcaaa tatccaatac ttgatcctaa taaactgata
     6421 ataaggatcg gatgacgccc aaaatgatca cttaagctac cgagaatggg ggcagataag
     6481 aaggcagcta gagcataaac agacatgagc aaagtgatat agaaagcttg ctgatgtatg
     6541 gagtgagaat aaggcagcgt taaaaacgga agtacaggac tgacgatagt aaatcctaat
     6601 ccagtgaata agacagagac gtatccaaaa actttagaat gtttatttgt gaaactgtac
     6661 atgtaaaaac tcctttatgc aataatgtta acttggaaac aaaaatagtg tatagtaatt
     6721 ttgtttcctt gtcaacattc taaggaacag cgaaatctac ttaatttatt tattccgaaa
     6781 agtgaagata cgcatcaaaa acatgaacaa acaaaaatca agtagacgac attgtaaatc
     6841 tgaccgatca gtgaagtaaa tagaaaagaa acctgttctt gcttcccatg ttttttttac
     6901 gtatactgtg attgagcgga ggagaaatca tgttgaattt agaaaattac ttaagcgctg
     6961 gacaaacagt catatctaat cttttactta aaaattatca taggatcggt ctacaatctg
     7021 aagaattttt atttgttcta cagttgcata tggcacagct tgaaggagat actttccctg
     7081 atttgcagat gattgctatg gatatgggaa tcaaacaaga tcagattttt caaatactgg
     7141 atcgtctcgt aacaaatgga tttatcaaga tagaaacgac gattgtcaac ggtaaaaaag
     7201 cagatcgata taatctttac cccatctatg atctattagg tgagtattta aaaacacaag
     7261 aaaaaaaata cgaagaaaaa acacaagaaa aagaaatcca gtcagtgtat caattatttg
     7321 aacaagaatt tggacgcccg ctttcttcga tcgagttcca gcggatcgga caatggctag
     7381 aagaagacca ttatcagccg gaaattttga agctagcact gcgggaagcc gtattaaatc
     7441 aggcttatag ttttaattac gttgaccgca ttttgctatc gtgggaaaga aaaaatctac
     7501 gtacaaaaca acaagtggaa gaagaccaaa aacgaagaaa acagcagctt cttcaaagag
     7561 aagtagaaca gtcagctcaa caagaagaat tgccgaaagt ctcactgaaa aattggttgg
     7621 aggagtagcg gaatatgtta agcaaacaaa aaacaatgga agctctagaa acgatgtatg
     7681 gaatgtttcc cgaagcacat ggagaactca agcacaataa tccatttgag ttattgattg
     7741 cagtgatctt aagtgcccag gcgacagatg tatcagtgaa taaagcaacg ccagatttgt
     7801 ttgcctcttt tccgacaccc gatgcgttag cagaagcttc aatcgatgaa atcattctta
     7861 aaataaaaac gattggtttg tatcgaaata aagcaaaaaa catcaaagcg tgtgcacagc
     7921 agctgattga acgtttcgat gggcaagtgc caacgtcaag agaagaattg atgtctcttc
     7981 ctggtgtagg cagaaagaca gcaaatgtcg tattggggga tgcattcggg ataccagcaa
     8041 tcgcagtaga tacccacgtg gaacgtgtct caaaacgcct gaggatctgc aaactagatg
     8101 ctacggtcat ggaagtagaa gaaacactga tgcggaaagt accacaagaa ttatgggtaa
     8161 agacacatca tacactgatt ttttttggta gatatcattg cacggcaaga aatcccaagt
     8221 gcgaggtatg tcctttgcta tcaatatgtc aagatgggaa aaatcggatg cgtctaaaag
     8281 aaaaggcgct aaaaaagaaa ccacgcctgt agacgtggtt tctttaattg caaataaatg
     8341 tatgaattat cttgttatta tggagaaaag ctgtttcgtt tatctttttt gcatgaaaaa
     8401 gtaaatgtac atactcagta gctaggatgg taacttatta caatttattg cgataaaaat
     8461 aaaagttgtt atttttattg ggaaaatacc cgatgtagaa aataatgcct tccaatatac
     8521 ctataaaata agtccagtat tccaaaggat tatataaata agtgacgtat ctatctaaag
     8581 gtgtaataaa aatgataagt gataataaaa aaataccatt tataactaaa cataaactaa
     8641 tggatttggg cggtttcagg ctcatcagaa aaatatagat tctggtgaac aacaaccata
     8701 aaaaagtgag aatcattgca tgagagcttc tttccataaa ttttccttta agagtagtgc
     8761 ttaaaagtac agaaaaaata ataaatgcaa ggataggagc aattaaagta aatttattta
     8821 ataataaaca aaatttttca gcttttttat tcttggaata acgaggtatt gttttcgata
     8881 aaaaaagatg gtgcagacaa attatgataa ttaagcatac tatcagataa ctcaaaatga
     8941 agccttcttt caaaaaatta ttcaaaacca tatattgtat tttttatttg ataataacaa
     9001 tgggattatt aagaagtggc actaaataaa agactagtgt gtatttagcc gatttaatta
     9061 taaacaagta aatggataaa gtatatgtaa tgataaaaga aaaatggatt ttctaatttt
     9121 taagctaaat gttagatcac acatgtatat gctggatagt cttataaaaa atcatgtaat
     9181 acagcttggt acatgatttt tatttgtagc tgttttttac atagacacaa aaaagaaacc
     9241 acgcttgtag acgtggtttc ttttttacta tctgtttcca gaagctgagg tgctgctgga
     9301 tggtgtatgg tcatttgcag catccgctcc gctagttgct ggctcactgg aagaagcagg
     9361 aggagcagat gaagacggtg tcgagctttc ttcggatgaa gaagaaggaa ccgttgttga
     9421 agacgctggc tcgcttgttt ctgctgtcgt gctttctttt gaggactcag cagttgattc
     9481 gctttgacta gtagagctag agctttgagt cgttgtctct gttgttgagc ttccaggagt
     9541 ctggacatag ctggaagatg gaatagttgt tgatggtgta attgcattcg atctagctgt
     9601 atattgatct ttgtagtaca gttcaccgcc cacacgaatt aatccgcttg gcatctccca
     9661 gtctgtattt gtcacgttag ctgaaacata ctgcataagc tcgcgataaa catcagaggc
     9721 tacgtgtgac gattctgaag tgacaggtgt cattttttta ttgtaacctg tccacacgga
     9781 aatcgaataa tttggcgtat agcccgcaaa taggatatct ggatacaccc cagaagaaat
     9841 accaagtttt gcatactcgt catctgtgta attggatgtt ccggtcttac cggcttgata
     9901 taacccagcg atttgcgcat tcgtaccagt tccttcagtg atcgtatctt ttaaaatgtc
     9961 tgtgatcata taagctgttt ctggagacat ggctgttttt ccatctggct cataagtttc
    10021 ttctgttccg tcttggaaga cgattttatt aacatattga ggtttgtaat aagtccctcc
    10081 attggcgaaa gccgcatagg ctgctgccat ttttaaggaa gaagctccgt attttgtccc
    10141 atcttgttct tccgtattac tagagatcgc attcgattga tggatcgtac tgtattcgat
    10201 cccaagattt tttaagaaag aagccacttt atctgaaccg acttcattga ataatttgac
    10261 tgctggaaca ttacgggata agtaaagtgc ttggcgtaaa gtaatggtgc ccatatattg
    10321 attatcccag tttcctacag gagtcgaagt cccttcatag ttatacggtg cgtcagtaat
    10381 agtttttcca gtagaatatt tcaaatattc aaaagctggt ccgtaatctg tgacaggttt
    10441 catcgtagaa ccaaaatcac gggaagtatt cactgctaag ttgttgccta aagttacgtc
    10501 ttctgcgatg tgacgtccgc caatctgggc ttttactttc ccggtattgg tgtcgataag
    10561 ggtggaggca acttgcatct cgtcgtctgg gtaagagaca tactgatccg tgttgacgat
    10621 atcatatagt ttcttttggg cgtccagatc caaattcgta taaatctcta aaccgtctgt
    10681 gtagacattc ttatctgttt tttcttgtac ttcattgatg acttctttga cataattatc
    10741 gacgatctta gtattgtcat cggattgagt tagttcttgc agaccatccg ttaccggtac
    10801 attaacagct tgatcatatt ctgtttgaga gattttttcg ttttgaagca tcgtatacaa
    10861 aacagtatct cgtcttttct tcgcctgatc tggataaaca taaggatcat aggcggaagg
    10921 ggcttgaggc atcccagcaa gcaatgctgt ttgcggtaaa gaaagttctg ataatttctt
    10981 accaaagtac atctcagaag ctgtctccat cccgtacaag ccgtttgaca tatacacttt
    11041 atttacgtag taggtcaaga tctcttgttt cgattttttt tgttccaatc ttacagccat
    11101 ccacgcttct tgggccttgc gtttcagagt ctgatcctcg gcactggtgg agaagaagga
    11161 aagtttgatc aattgctgtg tcaaagtact tccgccttgc agtccgccag aggtaaagtt
    11221 agagagggca gaaccgatga tccgaatagg gtcaaccccg atgtgtttat aaaaacggcg
    11281 atcttctacc gacacgatcg catcttctaa tgttttcggt aattcattcg cagaaatttt
    11341 ttcacgcttt tctgcgccta aatcttcgaa tagttcgcca tcttgtgtat atagtttgga
    11401 agatacggta gcgtctaatt ttttatccgt caattcgggc gcatcttttg cgtaatacca
    11461 gaaaagtcct acacctgcta aaaagaggat acagaaaaat gagagtattc ctaaaaggat
    11521 cttgataaat aatccttttt tatgtgttcc agaggacttt ccagaacctt tgccagaatt
    11581 cttcttcaca ctctttttag gagtaggctg tttctgtcgt ctagagcttc tagtttgttc
    11641 atttgccatt cttgctttct ccttcaatag ataatgttga taaatagaag tcaaccgcgt
    11701 ccaaataagg aatccgcgga gaaataccag ttttgatctc tattcctagt tcttcgatca
    11761 aagataaagg tagtgatttg cgtccttttt ccttttgggc gtcccagtaa gcaatcaaat
    11821 gaacactatt caaataaaaa cagcgcttca aagacgaaaa ccataacaag acaaagcaga
    11881 ccccattttg ttcgaggcat gctttcatat gttcgatttg atgggcatgg aagtttttaa
    11941 agggaaaaga tgttttgttc ttggtttctt ttgcttcaaa gtccaagtaa aagcctcgat
    12001 agacgccatt atagtctgta gttgaggctt gggtaaagta ggcttccttg atcacagcag
    12061 cacttctctt aggatagtct actttcacga tttggatagg ggtaggcttt ttatggataa
    12121 ccgccaaccc gcgggaaaga taatatttat tactttcatt gattgcttct tcaaagcgca
    12181 tcccccgatt gccgaattca gtgatctgat ttcttttttc ttgaattttt tcgacgggag
    12241 aggcattctt ataataaggt tggccatttg gatagcgcaa taccatcttt aatcacactc
    12301 ctaggccaca ttatagcaaa aaagcggata gaaagaaaag gaatctgaga tggataagtc
    12361 aaaagtaatc tatgtgtctg ggtatcgaag tttcgaactc ggtgttttta aagaaaatga
    12421 tcctaaaatc caagttgtta aaaatgtttt aaaaaaagaa ctccatcagt tagcagaaga
    12481 agggctggaa tgggtacttg tcagtgggaa tttgggcgtc gaactatggg ctgtgcaaat
    12541 agtagcggaa ttgaaagaag aatatccgga actatctctt ggtattttgt atcctttttc
    12601 tgattttggt aataactgga atgaagggaa ccaagaaaaa aaacaattag cagaacaatt
    12661 agcagattat gtcgaagctg ttagccatca accctaccaa tcacctagtc agctaaagaa
    12721 tcacactcgt tttatacttg agcatacagt gggctgtctg ctgatctatg atgaagaatt
    12781 ccctggaaaa acgaagtatt tttttgaaga tgcacagaat taccaagcag atcatcccta
    12841 cgaaattcgg ctgatcagta tggacgatct tcaaaatttt agtgaataat cgatattgtg
    12901 tttgatttat caactttttt cctatacaat gaaaaaggta gaaatgttat tacgtaaatg
    12961 aaaactagag gtgtaaatat ggcgaatttg gtttatagtc ctaaagacat tttacaacaa
    13021 gaattcaaaa caaaaatgcg cggctatgat cccgttgaag ttgatgaatt cttagacaat
    13081 atcatcaaag attatgaaac ttacagcaaa gaactccttg ctttacaaga agaaaacgat
    13141 cgattgagtg caaaagtagc tcaattatct aaaactcaag gagcagctca aacacgcgtg
    13201 caacaaacag aggcaccaaa gagcgcagca gtgaccaatt ttgatatctt aaaacgcttg
    13261 tcaaatcttg aacgtgaagt atttggtaaa aagcttgatc aacaagcaag tgcagtcaaa
    13321 ccagcacaac ctaatccaaa taactacaca aatgcagaca caagcttaga tgataatgaa
    13381 aaaacacgtc aattttaatt tttgattaat gaatttgcgg ttttcgggta atcgcggtct
    13441 gacttgatca ggctgaggaa agtccatgct cgcacaggct gtgatgcctg tagtgttcgt
    13501 gcttagcgaa accataagct aaggtactct ttggagtaac ggcaggaaaa caagctaagg
    13561 cttcggctat gcttaagtat ccttgaaagt gccacagtga cgaagcggct ggggaaaccc
    13621 atccggtgga acgcggtaaa cccctcgagc gagcaaccca aacaatggta ggggcgcttt
    13681 ttgtctggaa gaagaacagg acaaaaaggc agtataactg cagatagatg gttaccgctt
    13741 tgttttttct ccctggaaaa gcaaagtaca gaacatggct tatagaaaac cgcaaacatc
    13801 agggaattag gtcgtgacaa aagtaatgcg ttataagaaa caagaaaaac atttgaaagc
    13861 tatttttcaa tacttcagat gaatcgttct tattacaaaa caaacttttg tatcaccggt
    13921 tattcggaat ttgagtaaaa gtgtggggta ggactgatgt cccacctcct ttttttataa
    13981 ataaggagat tgtgtatgga aaaaaacagg aagttcaacc tcgtcgcaac tgcggcaagc
    14041 gggctagaag cactggttgg taaagaatta agagatcttg gaatcgaatg ccaagttgag
    14101 aacggacgtg cacgttttga aggaacaatg gaaacgatcg ctacagctaa tttatggtta
    14161 cgtacagcag atcgagtaaa aatcgtggtt ggggaattcg atgcgtatac gtttgatgaa
    14221 ttgtttgaaa acgtaaaagc attgccttgg gaagattttc ttccactaga tgcagctttt
    14281 cctgtagctg gaaaatcgat caagtcgaaa ctatatagca cacctgattg ccaagcgatc
    14341 acaaaaaaag caatcgttga acgtctccgt acctattatc accgtccagc ttctgtacca
    14401 ctgacggaaa ctggcgcaca ttttcagttg gaagtagctt tgctgaaaga ccatgtgatg
    14461 gtaactctgg atacgacagg accaagttta ttcaaacgtg gttatcgctt agaaaaaggt
    14521 ggagcaccat tgaaagaaaa catggcagca gcacttatta tgttgacaaa ttggcgaaaa
    14581 gaccgtccat tttatgatcc tgtatgtggt tcaggtacgc tttgtattga agcagcctta
    14641 ataggccata atatcgcacc aggattcaat cgtgagtttg cttgcgaatc ttgggattgg
    14701 ttcagtcaag aaatcatgga aaatgttcga tcagcagccg aagaaaaagc agattatgat
    14761 attgaattag atattactgg ttcagatatc aatggacgga tgattgaaat tgccaaagcc
    14821 aatgcagaag aaatcggatt aggctcttcg attaccttta agcaacaagc agtcaaagac
    14881 ttcaaaacgg ataaagaata cggggtcatc gtggctaatc cgccttacgg agaacgtcta
    14941 ggagaagaag aaactgttcg gaaattatat aaagaaatgg gcgatgtatt ccgtccatta
    15001 aaaacatgga gtaaatatat cttgactagc gacttagcgt ttgaggaatt ttacggacaa
    15061 aaagcaacca aaaaaagaaa attgtacaat ggtgcattgc gtacggatct attccagtat
    15121 tggggaactc gtccgcctag aaaaaaagag aaagacgaat aatcttacta attgattcat
    15181 tcaattggat gtttggagga atagggaatg aaagaaaaag agtttttaca agaagtaaaa
    15241 gaaatcaatc ttctacaaca agctttagga atcctcgatt gggatacaca aacaggtatg
    15301 cctgaaaaag ctagtgcata ccgaagtgaa gtagacagct atctttacag catttatttt
    15361 tcaaaaaaaa tcggtccaaa aatcaaagaa gccattcgct atttttctga acatccggaa
    15421 gaattgtcgg aagttggaac tgccgttttt gccaaagtaa aagaagagta tgatttggaa
    15481 catcgcgtac cggaagatct tatgagaaaa tatacagctg ccgtttcttc agcacacgga
    15541 caatggcaaa aagctagaga aacacaacaa ttttctgatt ttcaacacgc attgaatcaa
    15601 aatattgaat taacaaaaca gttgatacct tactggagaa aagatgaaaa gacgaattat
    15661 gatgttttgc tgaatcaata cgaacccggg atgactgtcg aaatccttga taaggtattt
    15721 gatcagctta aagaaggaat tctttcgatc cgccgtacgc tccaagaaaa agggactgaa
    15781 cctgaaacag actttttaaa tcggagaatg acgaaaaaac aacagaagag atttgtagtg
    15841 aaagtaatcg aacaacttgg ttatgatttt agtcgtggtc gtttagatga cactgtccac
    15901 ccatttatga ctggaattaa tccgaatgat gcacgaatca cgacacgatg gaacgaaaca
    15961 gatttcaaaa tggctgtttt tggagtgatc cacgaggctg gtcatggtat gtatgaacaa
    16021 gacatcgatg ataaatatgc gtatacaccg gtttatgaag gtacatcaat gggtatccat
    16081 gaatcacaat cgttgtttaa cgagatcatt attggaagta gtcgcagctt ctggaaaaag
    16141 caatatcctt tctttcaaga atgtgcagaa ggaacattcg atgatattcc ttttgacaaa
    16201 ttttatcgtt cattgaacca tacaaaatca agtttggttc gtatcgaggc agacagtttg
    16261 acttaccctc tccatatcat cattcgttat gaaatcgaaa aaatgatttt caatgaaggg
    16321 gtagatgttg ctgaactacc tgaaatatgg aatcaaaaat atgaagagta tctgggaata
    16381 cgaccaacaa atgatgtgga aggcatccta caagacgttc attggtcagg tgcaagcttt
    16441 ggttattttc cctcttatgc attagggtac atgtatgcgg cacaattact tcattctttg
    16501 cagcaagaaa tagatgtgga aaatgttcta gcgtcagacg attattctcc aatcaaaaac
    16561 tggatgtcag agcatatcca tcaatatggt gcatctagaa aaccaaatca attaatcatg
    16621 gatgcaacac atgaaccgct taatccgcaa tacctgatcg actatatgaa agacctgtat
    16681 tttaatgtat atcaggtaaa ataaaataca atttacaaag atagctgaaa ttcatctaat
    16741 ctatagatgt tttcagctat ttacttaaga aagaagtgga acgaatggat aaattacaag
    16801 tgatcgctga ttatagtatg gaccaattag cgcatgatca aacaggacat gggagcgatc
    16861 ataccaaaag agttgtcaag ttagctgaaa aaattttgga gacggaaccg caggcagacc
    16921 gctttgtgac gcttgcagca gcttacctac atgatacgat tgatgataaa gtcgttaaaa
    16981 atgagaacga ggcaaagcaa cagcttcgtg tattccttcg ctctttgcca atagtagagg
    17041 aacagatctc gatgattttt tccattatcg aaaatatgtc cttttctaaa aatctctctg
    17101 aagcggccga actatctctg gaaggtaaga tcgttcaaga cgctgatcgt atcgaagcat
    17161 taggagcaat cggcattttg cgtactgctt atttcggcgg tggacatggg cacccgattt
    17221 ttgatcctga actgtatccg caaacattca aggacaaaga aaattaccga aaaggcacga
    17281 cagtgatcaa tcatttttat gaaaaactgt tcttgctgtc tgataaaatg aatactgatt
    17341 acggatatga agaagccaaa cgaagagaaa ccttcatgcg tgaattctta gaagaatttt
    17401 ttctggaatg gtctattgac gatgaaaatt ttactccaga caattggatc aaaaataaca
    17461 aaaaatgatg gaggttgtga cagaagtggt cagctccaag atatttcgga tcattttccg
    17521 taaaagttac ttctggaaca ctgtttacca agaggtcgtg agcctgccgt tcagctccga
    17581 gtcacaagga acaatttcaa aaaatagctt ctcgtgtttg atgaatattg taacttgtga
    17641 ttcggaattg gcaggagaac accgtttatt cggaagaata ggactgtgac aagacttttg
    17701 tcacagtcct tttttcgaat tcaacaagta aaacttttaa gaaatattca gagagtaaaa
    17761 ttaaaaattg ctgataaacg aagatggaaa ttttatgtat ttttattggt ctatgcaata
    17821 aataaattaa atattcagaa tacaattgat tttaacgaaa gggcttctat caatggttgt
    17881 gttgtattta tctgcccagg tagagtaaaa tagatcatta tctaaaaggt aattgttcat
    17941 actatataag tcatttgaaa gtaaaaagat actgtaaata aaaaatgtgg ttaaataatt
    18001 ctcataatca gtgtaagcgt tatcaaaaat atagcatact tgctttgtag atgaatgaca
    18061 cgatatatgt ttggtatgtt ctgcaagaca gatgaatatg gaggtggaga caatgtcttc
    18121 caaagaacta acaatgtatt tagagaaaga attggatcaa ctgaaagaaa aggggttata
    18181 caatacgatc gacatactag aaagtgaaaa tggtgcttgt atcatcgtag acggaaaaaa
    18241 gatgatcaat ctagcatcca acaattatct tggatttgcc aatcgcgaag aattgaaaaa
    18301 agcatgtatt gaagcaaccg aaacttatgg tgtaggagca ggagcagtcc gaacgatcaa
    18361 tggttcgctg aaaatccatc agcaattaga agaaaaaatc gcagaattca aagggacaga
    18421 agcagcaatc gcctttcaat ctggattcaa ctgcaatatg ggcgctatct ctgcagtaat
    18481 gacaaaagaa gatgctatct tatcggatga attaaaccat gcatctatta ttgacggttg
    18541 ccgcttatcc ggagcaaaaa tcatccgaat taaacatcaa gatatgaaag accttgagaa
    18601 aaaagcaaag gaagcgatag aaagtaagaa atataaaaaa atcatgtata tcacagatgg
    18661 tgttttctcc atggatggag acattgcacg attgccggaa attattccga ttgttgaaaa
    18721 atatggactg atcacctacg tcgatgatgc gcacggctca ggcgtaactg gaaaaggtgc
    18781 aggaaccgtc aagcattttg gattaagcga caaaatcgat atgcaaatgg gcacgttatc
    18841 gaaagctata ggtgttgttg ggggttatgt agctggatcg aaaacactaa tcgactggtt
    18901 gaaagctaga agtcggccat tcctattttc tacttcgcta actccaggtg cagctgcagc
    18961 tgcattggct tcgattactt tgatgcaaga acatccggaa cttgtcgaaa aagtttggga
    19021 aaatgctaat tattttaaag aagaattgaa aaaagtaggc tataacatcg gtatgtctga
    19081 aacacctatt actccagtca ttttgggaga cgaaaaagtg actcagactt tctctaagaa
    19141 gctgatcgaa catgggattt atgctaaacc aatcgtttat ccaactgtgc ctcttgggac
    19201 aggcaggatc agaaatatgc cgactgcgga acatacgagg gaaatgcttg atgaagcagt
    19261 agcagtttat caaaaaatag gaaaagaaat ggaaattatt taactaaatt tagttttttc
    19321 gtctatttaa aattagagaa catgttcacg catatattgt taatcatctg aagatagtag
    19381 taaaaaagat cagggaggat catcatgaaa aaagtattgg tgacaggatg tttaggacaa
    19441 attggttcag agttgatcac acggctacgt caagaactag gcagtgaaaa tgtcattgcg
    19501 acagatatac gcatgcctga agtcattgag aaaaacgata tctttgagat cctagatgta
    19561 atggattacg aaaaaatgcg cagcatagca gaacaatatc aagtggacac attgattcat
    19621 ttggctgctc ttttgtcagc tgttgcagaa gcaaaaccac aattagcctg gaatttgaac
    19681 gtgactgggc tggtcaatgc attggaagtc gctagagaat tccagctgaa attttttacg
    19741 ccaagttcaa tcggcgcgtt tggtccaaat actccaaaag atcatacccc acaagatact
    19801 cttcagcgtc ctacaaccat gtatggggta acgaaggtag ctggagaact actatgtgat
    19861 tattattatg tgaaatatgg cgtagatact cgtggtgtcc gtttccctgg attgatttct
    19921 tatgcaacct tgccaggagg cggtacgaca gactacgcag tcgatattta ttattcagca
    19981 atcaaagaag gaaagtacac tagtttcatt gatcaaggta catcaatgga tatgatgtat
    20041 atgccagatg cgatcgatgc cattataaaa ctcatgaatg cagatcctga tcgattggtt
    20101 catcgaaatg ccttcaatat atcggcgatg tcttttgacc cggaagagat caaagcatct
    20161 attcaaaaaa tcataccaga ttttgaaatg gattatgatg tggatcctgt acgtcagtca
    20221 atagcagaat cttggccaaa ttcactagat gtttcttgtg cgcaagagga atggggcttt
    20281 tcgccgaaat acgacttaga tgtgatgaca aaggatatgt tggaaaaact gaaagaaaaa
    20341 ttggtagaga cggtataaaa caagaaccac atccaaaaag ttttttatac ttttgggatt
    20401 ggctatggta tgaaagggga caagggatgg aagaatatca agccacgcca gtaaaagaag
    20461 taaaaataga aaatgaatta aaacgtacga tgggattttt tactgcttta tcgactgtta
    20521 tgggcacagt gatcggtgca ggggtatttt ttaaagccgc aagcgtagca gaagttacag
    20581 gatccgccag tttgcatatg ttttcttggt ttctcggtgg tatgatttct gtctgtgcag
    20641 gactaacagg agctgaactg gcagctgcta ttccagaaac aggagggatg attaaatata
    20701 tcgaacggat ttacggaaat acagcagctt ttttattggg ctgggcgcaa gtcgtgattt
    20761 attttccagc aaatgtagca gccttgtcga tcattttcgg tacacagttc gtcaatctat
    20821 ttggtctttc ccagtcaatg attgttcccg tagctgttac agctgctgta tcgatcctgt
    20881 tgatcaattt tttaggttct aaagctggag gggcttttca gtcgattacg cttgtctgca
    20941 agcttattcc tttgtttgtg atcgtcattt tcggtttgtt ccgacaagaa ggagtagact
    21001 tccaactgtt tccgatccaa gcaggagaaa atctttcatt tttctcagcc ttgggagcgg
    21061 gcttgctagc aacgatgttc gcatacgacg gttggataca cgtaggaaat atttcgggag
    21121 aattgaaaaa gccggcgaaa gatttgccaa aagcaatttc tttaggaatc atcggaatca
    21181 tgatcgttta tttattagta aatgcggtgt tcttaagaac cgcatctatc gacggagtcg
    21241 caggaaacag caatgcggca agtgacgttg caaaaatgat ttttggcggc ttcggtggaa
    21301 gactggtcac agttggtatc ttgatttctg tttatggaac catcaatggc tataccctta
    21361 ctggaatgcg tctcccttat gttatggcaa aagaaaacaa cctgcctttt agcaagctct
    21421 ttgctaaact tcatgataaa actaaagttc ctgtagccgc aggtatctta gagctagtca
    21481 tcgctattgg catgatgatg atcggtggtt ttgatacact aacggatatg ctgatctttg
    21541 tcatttggat tttttatacg atggtctttg ttggtgtcat tcttcttcgt aaaaaagaac
    21601 ctgatttgtt tcgaccatac aaagttccaa tgtatccgtt tattccacta gtagcaatca
    21661 ttggagggac ttttatcgta tcaagcacgc ttatcactca gaccttttta gcttcgatgg
    21721 ggatagtatt gacacttgct ggtatcccga tttatctcta tttaaaacgt agatagctaa
    21781 aacattcgaa ttttattaga actgcacttc tctgccaaac aaaatatttt atttaaatga
    21841 ggagtacgtg gaagaaatgt caaaagtact cgttaatttt gatcacgtaa atgtcgtttt
    21901 gtctacgatg aaatagcaaa gtaaaagaca gaaatcgggc tcaaccgatt tctgtctttt
    21961 actttgattt gcgtaactga actattcggc gtacgccgcg ataaatattt aataaaacca
    22021 agcaaccaga aatgaaaatg ggaagccaaa tcagatagac agggtagcca agcactttag
    22081 acaaagcatg tggagtcatt ttatccattt caagaagtgc ttgctgccaa gtctgaagat
    22141 tgaagactag catgaaaccc gaaataatca ggagaataaa tcctaaataa tgaattgtag
    22201 ttctttttct tacataagcg atcgtagcat aaaggaacag taaaaaaata ggtacgccaa
    22261 aaacaaagta catattcagc atctcgacac cccctttgtg tttatcttac tttactttga
    22321 aagaaatgag aaataatagc ctcgttactt gcttgaaaca gcaaaggact gctaagataa
    22381 gagagataca aagaatcaag gaggagtcat atggcaagtt atatcgaacc gattcgtttt
    22441 gcgctgattg tttttccatt tttagcctta gcgatctcat ctgttttttt tatttatgaa
    22501 tatcgaaagt atggaacatt tctagtaaca agggcagtta ttttgtattc tttcgttttt
    22561 tatttattgt gtgcgtattt tttggtgatc ttaccacttc cggcaaagga gacggttgcc
    22621 caaatgacag ggccaaagat ggagctgcat ttatttgctt catggcaaca tttcagagac
    22681 aacacggtat tggtcttgtc tgaacctagt acctacctgc cggcaatgaa gcagagtgta
    22741 tttttggaac cagcttttaa tgttttatta ctcataccat ttggcattta tttaagatat
    22801 tatttccggc tttcttttat gaaaacgatg attgctagtt tctgcctttc tctatttttt
    22861 gaattgacgc agctaagtgg actttatttt atctacccaa gaccataccg cttatttgat
    22921 gtgaatgatt tagtgacaaa tacattgggt ggaatcattg gttttgtcgt tacgccgtta
    22981 tttacattta tgcttcctac aagaagacga atggatgaac tttcttatga aaaaggaaag
    23041 actgtctcat tgactcgacg cttggtcgct tatttgatcg actggacatt tttatctctt
    23101 attaatttgg tagcggcgat tttctttaaa attgcgttcg attcaggggc agttacttct
    23161 catatctggt ggcttttatt agaagtaggg gtatacttta tgattgtacc gtttataacc
    23221 aatggatgga cacttggcaa aaaaattgtg cgtatccgtt tggtggaaga agaccgcgaa
    23281 cgaatttctt taaaagcatt gatgatccgc tacgggtatc tgtactttct tttttatggt
    23341 ttaagctggt tggggcagtt gcttcagcaa atcatgaatt cgacaacgaa tacggtgttg
    23401 cagatgagtg cagtattcat ttctctcggt gtcttgttac tacaaggtat ttttatttta
    23461 aatatcttgc tatcattttt gagaaaaaaa cggattctgt tttatgaaaa agctagtcac
    23521 acatatactg ttagcacgat tggccaaaca aaggatgatg attctcgaaa ttagctgagc
    23581 aaaaacgctt tgtctgtgtt ataatgccaa agtcgtgata atttaaagag aagaggtgca
    23641 cgaatgaata attttgatat attccgcttc aaaccgttta tcaatgaagc gttaaccgca
    23701 aagggcttca aacagcccac agaggtccag gaacgtttga ttcctttaat tgcaaaagga
    23761 aaaaatatca ttgggcaatc tcaaactggt acaggaaaaa cacatacgtt tttgttgcct
    23821 ttgtttgaaa aaatcaatgc agaaaaagag gaagtacaag ttgttattac agctccaagt
    23881 agggaactag ctgcacagat ctatgaagca gctacacaaa tcgctaaatt ttctacaccg
    23941 gagatccgtg tctcgaattt tgtcggcggt acagacaaac agcgtcaatt aaatcgtctg
    24001 catcaccaac agccacaggt tgtagtaggc acgcctggta gaatattaga catgatgaat
    24061 gaacaagcgc tgaagattca caccgcattt gcatttgttg tcgatgaagc ggatatgaca
    24121 ttggatatgg gttttttaaa tgaagtagac caaattgcaa gtcgattacc agaaaagctg
    24181 cagtttttag ttttttctgc cactattcca gaaaaacttc gtccattctt acgaaaatac
    24241 atggaaaatc caatcattga agaaatcaaa ccaaaagcag ttatttctga agacattgaa
    24301 aattggctga tttcaacaaa aggtaaagat gagaatcaaa tgatttatca actgctgaca
    24361 attggtcatc cttatttagc aatcgtattt gccaatacaa aacagcatgt ggatgaaatt
    24421 gccgattact tgaaaaacca aggcttgaaa gtagcaaaga ttcatggaga catcacccca
    24481 agagagagaa aacgagtgat gcgacaagta cagaatctgg agtatcaata tgttgtagcg
    24541 actgatttag ctgctagagg gatcgatatc gaaggtgtct ctcatgttat taatgcagaa
    24601 attccagaag atctagactt ctttatccat cgtgtcggac gtactggacg taatggctta
    24661 aaaggaacgg ccattacgtt atattcgcca aatgatgagc aagccattga tgcgatagaa
    24721 aaattgggcg tctcatttga accaaaagaa atcaaaaacg gggaaatcgt caaaacatac
    24781 gatcgtaata gacgtgccaa acgagaaaaa tcaaaagatg tattagatcc cacgctgatt
    24841 ggtcttgtga agaagaaaaa gaaaaagatc aagcctggtt ataagaaaaa aatcgattgg
    24901 gcaattgcag aaaaaaataa aaaagaacgc aaaatcgaac gcagacagca aagccgtact
    24961 gctcgtaaaa ataagaaaaa ttcacataaa taaaaaacaa gaggttgtga caaaaggcgt
    25021 gtcacaatct cttgttttta agctagactt tttttcattc cgatacaaag tacttcatct
    25081 tcaataaaag gttctgtgca agtatgatac ccttgttttt cataaaaatc tacagccgtc
    25141 atttcagcta ctacataact agtctgacaa ccttctgaaa ccgcccgttt ttcagcagct
    25201 tcaagcaact gaccgcctaa cccttttcct cggtattctt ttgctacgca aaatcgttcc
    25261 ggcttgaagc aagtaggtgt tttcttttca taacgcaaag tagctactgg tcttttttga
    25321 tcaagaaata gataataggt ttgttgcggg atatcttttc cgtcgaattc tagttctgca
    25381 ggaatccctt gttctaatac aaaaacttga tatctcaaaa agcagctagc tgcgcgtatc
    25441 cattcatccg ctccaactat ttttttcatc atattcctcc ttgtcatgaa tagcagagat
    25501 gtattgattc ctttattctt atcgtaccaa aaatcgtgga gtatgaccaa aaggaaatga
    25561 aaataaaaat tgagatattg acagtgatca atagaatgcg tatactaaat aagtacgaaa
    25621 aggatatgat ttgtttttta agactcacag aaaattcttt cttggctgaa aaaagaatag
    25681 tcactaatca aattgctccc tttttctatt ttggtagaaa taccgacgca gctcagcgtt
    25741 atcgagttta agaggtaatg attacacatc attgcaatca aggtggtacc gcgagttttc
    25801 gtccttggct gtgatggtgt ttttttgtat ttaatttata gaaagcaggt aatgacatga
    25861 aacaattaag tagtgcacaa gttcgacaaa tgtttcttga tttcttccaa tctaaaggac
    25921 atacgattga acctagtgcg tctttgatcc ccgtgaacga tccaacctta ttgtggatca
    25981 actctggtgt tgcaacattg aaaaaatatt ttgatggttc agttgtgcca gaaaatccaa
    26041 gaatcacaaa tgcccaaaaa tctattcgaa caaatgatat cgaaaatgtc ggtaaaacag
    26101 cacggcacca tacgatgttt gagatgctgg gtaatttttc gattggtgac tatttcaaaa
    26161 atgaagccat ccactgggca tgggaatttt tgactgatcc aaaatggatg gcattcgatc
    26221 cagaaaaact ttatgtaaca gtttatccaa aagatacaga agcaaaacgc atctggcatg
    26281 aagaagttgg cctgccacta gatcacatta ttgatgtaga agacaacttc tgggatatcg
    26341 gtgcaggccc atgtggtccg gatacggaaa ttttctatga ccgtggagaa gcttataacg
    26401 atttagcaga agacgatcct gaaaactatc caggaggaga aaatgaacgt tatttagaaa
    26461 tctggaactt agtattttca gaattcaacc ataagcctga taacacattt gaaccacttc
    26521 ctcataaaaa cattgatacg gggatgggat tggaacgcat ggtctcaatc gttcaagatg
    26581 cgtcaacgaa ctttgagaca gacttgttta tgcctattat ccacgccgta gaaaagctaa
    26641 gcaaacaagt aaaatatggt gaaaacccag taacagatat ttcttacaaa gtaatcgcag
    26701 atcatattcg cgccctttca tttgctattg gcgacggtgc attgccatcg aatgaaggga
    26761 gagggtatgt cttacgccgt ttgcttcgtc gtgctgtcat gcatgggaaa aaattaggta
    26821 ttgaacaagc attcttatat cgtttagtcc ctgttgttgg ggaaatcatg gtaagttatt
    26881 atcctgaagt acttcaacaa aaagaattta ttgaaaaagt tatccgtaca gaagaagaac
    26941 gtttcaatga aacaatcaat gaaggtttgg aaatcttaaa tcaagtgatc caagaagtaa
    27001 aaaacgaaaa cgggacgact ctagcaggaa aagacatctt caaactatac gacacatatg
    27061 gcttcccggt agaattaacg gaagaggtgg cagaagatga aggactgaaa gttgatcatg
    27121 ctggttttga aaaagaaatg gatgcacaac gcgaacgtgc tcgctctgcc cgcagtactg
    27181 aaaaatcaat gggggtacaa tctgctttat tgacagatat caaagtagaa agtaaattca
    27241 ttggatacac agaacaagaa tcagatagtc aattattggt catcgttaaa ggtgagtctc
    27301 ttttgaatga agtcgcagaa ggtgaagctc aaatgatctt tgatcaaaca cctttctatg
    27361 cagaaatggg tgggcaagta gcggatcaag gatggatcat gaatgaagta ggcgaaatcg
    27421 tagcagttgt tacagatgtt caaaaagcgc ctaatggtca atttatgcac accgtagaag
    27481 taaaagcacc aatgagtgaa ggacaaacct atcatctatt gatcgatcaa tcgatgcgca
    27541 atcggatcat caaaaaccat acagcaaccc atctactgca caaggcattg aaagaagtac
    27601 ttggcgagca tgcaaatcaa gctggttctt tagtcgctcc tggacattta cgattcgact
    27661 ttacccactt tggtcaaatc acttcagatg aattagctga aatggaaaga atcgtcaacg
    27721 aaaaaatctg ggaagctatc ccagttgaaa caattgaaac agatatcgat acagccaaaa
    27781 acatgggtgc aatggctttg tttggtgaaa aatacggaca tgacgttcga gtagtaaata
    27841 ttggcggctg gtcaatcgaa ctgtgcggag gcacacatgt agcaaataca gaaaacatcg
    27901 gaatcttcaa aatcgtttct gaatcaggaa ttggtgcagg cgtgcgacga atcgaggctg
    27961 taacaagtaa agaagcgtac gaactacttg aagaagaaga aaaacaacta aaacaagtag
    28021 caacaattgt taaatcacct caattgaaag aagttgtttc aaaagcggaa caattgcaac
    28081 agcaagtaag agagctacaa aaggaaaatg aacaattagc tagcaagtta gcgaatcaac
    28141 aagctggtga tgtattcaaa gatccagaaa cgatcaatgg aaaaacaatc attgcagcac
    28201 aagtaaaagt gaaagatatg aatcagctgc gtcaattagc tgaccaatgg aaacaaaaaa
    28261 atatttcaga tattcttgtt ttagcaaacg aacaagaagg aaaagtcagt ctgctagcgg
    28321 caatgacgaa agaatcaaat gaagctggac taaaagctgg cgacttgatt aaagcaatcg
    28381 caccgaaagt aggcggtggc ggtggtggac gtccagacat ggcacaagct ggcgggaaaa
    28441 atcctgctgg tattccagat gcacttaaag ctgcgaaaga atgggttgcg caacaatagg
    28501 gcgtttacgt ttgacagaaa aacaaaagtt caaacattga acgaaacatg attatggggg
    28561 cgaagacaaa caagtcttgc cctcatactt ttttcaattg gatggcgcat ctaatcaaat
    28621 ggtcggattc ggatggtctt tagttgacga aagtgacaga aatttttacg attagtataa
    28681 ataaaaaggg gtgaaaaaat gaatagtaga aataagacct ttcgactagt cttacgtgcg
    28741 atcttgttag caatcatcat cgtacaagcg atggttcctt ggctggggtt tattccatta
    28801 ggattcatta gtttaacaat tatccatatc acagtaatta ttgctgcagt agtattaggc
    28861 ccaaaagatg gcatggtgat tggcttgttt tggggaatcg ctacaattgt tcgtgcctat
    28921 gccatgccaa caacgccatt tgatacatta gtgttcacga atccgattat ctcggtagtt
    28981 cccagagtac ttgttggctt agtagcaggc ttggttttcc actggattta tcaaaaaaaa
    29041 aaatcaataa cgatcagctc agcctttgca ggggtactgg gttcattggt caatacagtc
    29101 ttagtgttag gattcatggg attattttat acaggtgcaa cggcagatgc ctatggtgta
    29161 gactctgctc ttttatttaa aaccttagca ggggttgcag caatcaatgg gataccagaa
    29221 gcaataggtg cgggaatcat aacaccatta ctagcaaaag cgttatttgc agcaacaccg
    29281 ttgaaaccag aataatgacc atcttttaat agtaatagga cgcacgatag atagaaaaag
    29341 gaagagagga gaggaaaaca atcgtcctct ccatcttttt acctgagcaa caagcaaact
    29401 agaaggggta aaaaacttgg ctaagaaaca agaagaaaaa aagaaacaaa taccgcaaca
    29461 gcggacaaaa aaaggagtac tagcgggtat cttaggattg gttacgaatc tgatcttgtt
    29521 tgtctctaag ctaatgatcg ggcttttttc aggaagtgtc tccattatgg ctgatgcagt
    29581 gaacagtcta tcagatactg cttcatccat attgactttg atcggattta aaattgctgc
    29641 aaagccagca gatcaggaac atccttatgg acacgaacgc ttcgaatata tcagtgggtt
    29701 atttgtttcg atcatcatta cttatgtagg atttcaattt ttagagtctt ctgctgaaaa
    29761 aatcatccat ccagaaaatg tctctttaac acccatcgtc ttttttgtcc taatcatttc
    29821 catctttttg aaatttgcac aaggcaaaat gtatcaggtt attgcgcaat ccattgattc
    29881 tgaaacattg agagctacag caacagatag ttataatgat gtctttacta cactggctgt
    29941 attgctttca gcagcaatcg aatgggtaac tggatggcgt attgatggat atataggttt
    30001 tgctttagca ttatatatcc tttatagtgg attgacgatg cttcgaaatt ttgtatacga
    30061 actattagga agtcgcccaa cgccagcaga gattgaagaa atggaagagc atttaaatgc
    30121 ttgcgatgat atacttggct atcatgattt attggtgcat aactatggac ccaataaacg
    30181 ctttgcatca gtccacatcg aagtagatga atcaatgaat ttgaatgtgg ctcataagat
    30241 tattgatctg atagaaaaag actttaaaaa gtctttggat gtggaacttg tctgtcactt
    30301 ggatccaatg cctgttgata acgaaaaata ctataatatc ttgcggcagt taaagcaaat
    30361 tcttcttgaa acaggtacag ggcttaatat tcatgatttt agagtaattc atcaaggaaa
    30421 aacgctgcaa tttgatgtag tggtccctga gaaattccag tttgttgata cagaactaga
    30481 aagaatctta cgtagtcaaa tagaagaaaa aatcggagat taccaattgg aaattacgtt
    30541 tgatcacaat tatcttttat attaaatgag aaactataaa aagactcctt aaagttttta
    30601 atttaaagag tctttttttc ttttaattgt ttatggagag cctgacgtgc aagattatct
    30661 gctcctttat ttttgttttc gggcaaccat tgcaggatca ataaagaaaa ttcggataga
    30721 agttcttgga ttctttgaag gtagggaagg aagagctcgt tcttcgttgc gtttttgtcg
    30781 accgtagaaa ctagtgtttt gctgtctgaa aaacagaaaa tcgtttcatt ctgtaagtcg
    30841 tttttcttta gaaattctaa agtttttaaa aagacttcga actctgcttg atggtttgtc
    30901 cctatagaaa gcgggataga tagctgttct tgtttacctt gatagacaat caagattcca
    30961 cctccactag gaccagggtt gccttttgta gaggcatcaa tgtatacttt taacataaaa
    31021 agagattctc ctttttgttc aaactaatgt tatggtaaga ttatatcatt actgaatcgg
    31081 tgagaggtta gagaatgaaa aaaaatattc gatggcagcc tgaactggca catacgatca
    31141 tctattggtc attgaccttg atcattctgt tttttagtct gattctttct ttagaaaaca
    31201 caggtcctta ttggaaaagc aattttgttt taggtatttt tcttgttttt ctatttctag
    31261 gtttgcggcg ttcttttatt ttaaaatcaa actctgtgat tatacgttat gctgcttttt
    31321 ggaaagaccg agaaatatct gtcggacaga ttcgatcttt gacgccaact aatactgggg
    31381 tgcaaatgat gttgcaagat gagaaagccc catctgtttt catgatgcga aaaaaagatc
    31441 aagtagtcct ttttgatcat tttgaaaaaa acggacccaa atcagaatca attccttatc
    31501 cttatacgaa aaaaagaaaa agctaatttt aaaaatcaga acctaaaaaa acgaattttt
    31561 acaggaaaag aaaagagtga gacgtacggt tcatcccgtt tagcgtctca ctctatttgt
    31621 ttatctattc atgcatacta gtatcggtag tctgaacgtt gcctttcttg acatgggcag
    31681 cttgtgttcc tcgattccct tcgatgatct caaattcgac cacttgattt tcttccaaag
    31741 ttttgaatcc ctcttcttca atcgcagtaa aatgtacaaa aatttcttct gtgtcatcat
    31801 aactgataaa gccgtatcct tttttgttgt caaaccattt tacaattcct gtggtcaaag
    31861 cactcacgac ctttctaaag tctgatcata gccttcatta taaagagtat ttataagtac
    31921 gtcaaataaa ttaaaaacct gtaattttat gttttttttc tgaataaaaa aaggtataat
    31981 tggcatatct taacaaagaa gatattttgt tgaataaagt tcgtgaaaag gggtaatcaa
    32041 atgaagaatg atctgcaaat ttcacaagaa acagagctag aaccgattgt tgaagtggct
    32101 agtaaattag atcttaagga agacgatttg gaactgtatg ggaaatataa ggcgaaaatc
    32161 aatttttctg gaatcaatcg atcaaaggat aacgctgagg ggcatttgat cttagttact
    32221 tccatcaatc caacaccagc tggcgaagga aagtcaacga tcactgtagg gttaggagac
    32281 gcgctcaata aaatcaataa aaaatctgtt attgcattgc gagaaccctc acttggtcct
    32341 gtgatgggaa tcaaaggtgg tgctgcaggc ggaggatatg cacaggtatt gcctatggaa
    32401 gatatcaact tgcattttac tggtgacatg catgctatca caacagctaa taatgcatta
    32461 tctgctcttt tagataatca tattcatcaa ggaaatgaat tgaacatcga tgcccgccga
    32521 gtgatttgga aacgggtagt cgatctcaat gatcgtgaac tgcgtaaagt aattgttggc
    32581 ttgggtgggc caatccaagg tgttccaaga gaagatgggt ttgatatcac agttgccagc
    32641 gaaatcatgg ctatcttgtg tcttgcggca gaccttgaag atttaaaggc tcgtcttgca
    32701 aggatcgttg tcggctatac atttgaccgt cagcctgtga ctgctggaga cttgaaagca
    32761 gaaggcgctc tggcattact gctgaaagat gcaatcaagc cgaatcttgt acaaacaatt
    32821 tacggaacac cagcttttgt ccacggggga ccgtttgcca atatcgctca tggctgcaat
    32881 agtattttag ctaccaagac agcattgaga ttagcagatt acgttgtcac agaggcagga
    32941 tttggtgcag atcttggcgg agagaaattt ttagatatca aagtacctaa cttgaaaaaa
    33001 gcgccggatg ctgtggtgat tgtcgccact gtccgtgcat tgaaaatgca tggcggaatg
    33061 aaaaaagatg aacttaaaaa tgagaatctt gatgctttga aagtaggttt tgcaaattta
    33121 aagcgccata tacgtaatat ggaacaatat cagctacctg tgatcgtcgc aatcaatgaa
    33181 ttcgtaacag atacagacaa tgaactcaca ctgttggagc acttgtgtga aaatcagggg
    33241 attcttgcca agagagcgag tgtatgggca gatggagcag aaggcggcgt tgatttagca
    33301 aaagctgtag tacgattgat tgatagaaaa gaagctaatt acaagccatt ataccgccta
    33361 gaagaaacga tacaagaaaa gacagaaaca atcgtcaaga aaatttacgg aggaaatggt
    33421 gttgttttca gcaaaaaagc gcaaaaacaa atagaagagt ttacgaagaa tggatgggac
    33481 aaactgccga tttgtatggc aaaaacacag tattcatttt ctgatgatcc ttcactgcta
    33541 ggtgcaccgg aagatttcac catcacgatc cgcgaaatca tcccaaaatt aggggcagga
    33601 tttttagtag ccttgactgg agatgttatg acgatgcctg gtttgcctaa aaaacctgct
    33661 gcattgaata tggacgtgac aaatgacgga gaagtgttgg gattgtttta agcttgatta
    33721 taatctacca tcgaaggagc tgtattttga ctacagcttc tttttttaga cgatagggaa
    33781 ttaattttgt ttacactagg atcattcttt ttctttattg tattttgagc tatactaaag
    33841 cataatagga gggtatgatg aaaacgacat ttataagaaa aaccggtttt tacggtatgg
    33901 gtagctcgat tcagctaaga atcaacaatg aaaaacgcag tgttctcagt catgaacaaa
    33961 agataacgct tgatctggaa gtgcccttta cgatgcaggt caccttttat tggctaaaaa
    34021 gccccgttta tacagtgaaa gaagcaaagc ctgcttatgt gatcacaatg aattacttga
    34081 ttcttcaaat ctatccgttt ttatttctag caactgggtt gggggccgtt ttcctacaaa
    34141 atttattttt cagttttttt gcagttattg tgttgattgc gttctttttc tatataaaaa
    34201 accgggcata tttgatcaag gaggaaaatt atggcaaact ctgatctttt tttaatcagt
    34261 ttcaatcgaa tcgaaaaatg gatgagagac gagatgggaa atgcacgaaa tatgggattt
    34321 accgaacttg tcagacgcct agctcaaaga aaacaattaa tgatcagaaa atacgaagat
    34381 gatcttttac agcttgctca gttaaggaat gcgatcgtcc atgatcggat cgcagtcgat
    34441 tttgtcattg cagagccaaa tgattggaca gtcaagcgaa tccagctgat cgaacaagaa
    34501 ctgattcagc ctgaaaccgt gctgcctcga tttgcaaaac gtgtaacagg ttttgaacaa
    34561 gatcttccgt tacttgaact gttaaagata gtagcagaaa aaaggtattc acaatttccg
    34621 ttatacaata aaggaaaatt tgtagcattg attactttac gtaatatcgg gttttggcta
    34681 gcaaaagaaa gccaaaaagg tccggttgat ttaacaaata aacgagcgtt ggatttgatc
    34741 atccaaaacg gaaagtacac aaattatcat tttgttccag ctaaaacaca tatttacgag
    34801 gttgaagcga tgtttcgtga gcaagggact ttggaagccg tacttatcac taaagatggg
    34861 aatcccgatg gtaatctgct cgggatcgta cgacctcgtg atatttataa acaaatagaa
    34921 aaggattgat tttttgttaa ttatttattg gatattcagc gctttgctag taggagtgga
    34981 tcagttggtc aaatggtgga tcactgataa tctagcgctt ggagagacga aaaatcttat
    35041 accaggtatt ttgtcactga atcatattcg aaacactgga gccgcatgga gtatgctaga
    35101 agggaagatg tggttcttta ctatagtgac actcattgca gtcgttgtga ttctcacatt
    35161 gatgattaaa aatcgtgaaa aaggtaatcg ctggttcatg attggattga gtttgattct
    35221 agctggtgcg attggcaatt ttatcgaccg tattcgtctt ggctatgtag tagatatgtt
    35281 ccagacagat tttatgagct ttccgatttt taacgtagca gatgtgacac ttgtatgtgg
    35341 agtgatttgt atgttaattt atattatttt agatgaaaag gatcaaagaa aaaaatgaca
    35401 gaacttaaaa cgacgattca ccatgaatct ggtaggatcg ataaagtatt gactaattta
    35461 ttcaccgatt acagtcgttc gcaaattcag ctgtggctga aaaatggagc ggtttctgtc
    35521 aatggacagc cagtcaaagc aaattacaaa gtaaaacaag gagacgagat tactgtcttg
    35581 atccccgaac cagaaacatt agatgtggtc ccagaaaata tcccgttgac gatcgtttac
    35641 gaagatgaag atgtagcggt gataaacaaa cctcaaggaa tggtcgttca tccttcagca
    35701 ggtcatacgc atggcacaat ggtcaatgcg ctgatgtacc atatcaagga tctttctacg
    35761 atcaacggcg ttattcgtcc aggtattgtt caccgaatcg acaaagatac ttccggactg
    35821 ctaatggttg ccaaaaatga ccaggcacac gaatcattag ctcagcaatt aaaagataag
    35881 acctctttgc gcaaatatgt tgctttagtc catggagaga ttcctcacga aaaaggaacc
    35941 atcaatgcgc caatcggccg ttcgaaggaa aaccggaaaa tgcaggcgat aagagaagat
    36001 gggaagtcgg ctgtcacaca ttttactgta ttggaacgtt tcgaaggatt tactctggtt
    36061 gaattaaaac tagaaaccgg aagaacacac cagatccgtg tgcatatgaa gtatatcggt
    36121 tatccgttag ctggagatcc agtatacgga ccgaagaaaa ctttgaaagg caatggtcag
    36181 tttctccatg cgcaaatgtt aggttttacg cacccgacta caaacgaaaa gatgatcttt
    36241 gaagcacctc ttccagaagt ttttgaaaaa actttagaaa aattaagaaa aaacattgca
    36301 ttttaattta gataacggta tagtaattaa caacgaaagc ataaaactta atagaattcc
    36361 tttaagttta gtcccgtgag gctaagaagg gtgggagcaa ggatacgtat ggtgcgccat
    36421 aagtagattg ctcattgaca tagtatagct atcagtgtat cagtatacgc tcagtctaaa
    36481 cattcctcct gtcctcttag ggcaggagtt tttttatgca aaaaagtagg gggaatgaaa
    36541 atgcaagcaa aagaagtagt agatcaggta accatgaagc gagcattgac tcgaattact
    36601 tatgagatta tcgagagaaa ccatagtatc caagatatcg tattggtagg tatcaaaaca
    36661 cgaggaatct acattgcatc aagaattgcc gaacgcctga agcagctaga agatatcgat
    36721 attcctgtag gagaactgga tatcacttta taccgagatg acaaaaaaga aaatccagaa
    36781 gaaccggaac ttcattcttc tgacatccca gtttccttag aaggaaaaga agttattttg
    36841 attgatgatg ttttgtatac aggacgaacg attcgagcag caatggacgc agtaatggat
    36901 tttggcagac caagaaaaat ttcattagca gtcctggtcg atcgtgggca tcgagaattg
    36961 ccaatccgtg cagattatgt tgggaagaac attccaacat ctcgggcgga agagatttta
    37021 gtagagatgc aagagcttga tggacaagat cgcatcatga ttttgaaaga ggaagattag
    37081 aggagagaga aacatgtcgg agaaaaaagg atttcataat gatgacgtgg tgttagatat
    37141 ccacgatcgc ccaaccccag gacattgggt aggattaagt ttacaacact tgttcacgat
    37201 gttcggagca accgtgttag tccccatctt agtaggtatc gatccaggta ttgcgctagt
    37261 cagttcagga ctaggtacat tggtgtactt atttactact aaaggaaaga tacctgcgta
    37321 cttaggaagc agcttcgctt tcattgcagc gatgcagctt ttgatgaaaa cagatggtta
    37381 tccagcgatt gcacaaggag cagtcacaac tggattagtc tatttgattg ttgcgctgat
    37441 catcaaaaag atcggttcag catggctgga taaaatcttg cctccaatcg tcgtcggtcc
    37501 agtcatcatg gttatcgggt tgggacttgc ggcaaatgca gcaacaaatg ctatgtataa
    37561 tcagggcacg tatgatttca agtatattgc tgtagcgctg atcacattag gattaacaat
    37621 tttcttcaac atgtggctaa gaggttttct cggattgatt ccgattttac taggtattat
    37681 tagcggatac atcgtagcct tgctgtttgg aatcgtggat actaagccaa tcgtagacgc
    37741 tgcctggttt gctgttccta actttgagat tccctttgta caatatgaac caaagctata
    37801 tcttggagca atcacaacaa tggcacccat cgcttttgtg acgatgacag agcatatcgg
    37861 ccatcttatg gtattgaata aactaactaa acgtaatttc tttgaagaac cgggtcttca
    37921 taagacgttg acaggtgatg gattagcaca aatcgtggca gcctttgtcg gaggtcctcc
    37981 tgtaacaagt tacggtgaaa acattggtgt tctggctatc acacgtgtcc atagcgtgtt
    38041 tgtgatcggt ggagctgcag tatttgcagt cattttagga ttcgtaggaa aattaagcgc
    38101 tttgatttta agtatccctg gaccagtcat ctcaggaatc agttttatct tatttggagt
    38161 aattgccgca agtggaatga agattttaat cgagaacaaa atcgattttg ataaaaagaa
    38221 aaatctgttg attgcttcag ttatcttagt agtaggaatt ggcggactcg tctttgaagt
    38281 aggcacattt acattgtcgg caatggcatt agcaactgta cttggcatca ttttaaatct
    38341 tatcttacca gaaacttcac gaagcgaaga aaactaagga ggaaacatta tgatcatcaa
    38401 atcagaacgt atcagcttaa agcatttatt gaccgttgag gcacttactg atcaagaagt
    38461 tatgggcttg atccgcagag ggcaggaatt caagcaaggt gctaattgga ctccgcaaaa
    38521 gcgccagtac tttgctacaa acctcttttt cgaaaatagt actcgcacac ataaaagctt
    38581 cgatgtagcg gagaaaaaac tagggctaga agtgattgaa tttgaagcaa gcacaagctc
    38641 tgtccaaaaa ggggaaacac tatacgatac agtactgacg atgtcagcat taggcgtaga
    38701 cgtagcggtt atccgtcatg gtgatgagaa ctattatgac gaactgatac aaagtaaaac
    38761 aatccagtgt tcgattatca atggaggaga cggaagcgga cagcatccaa cccaatgctt
    38821 gcttgatttg atgaccattt atgaagaatt tggtcatttt gaaggtctga aagttgccat
    38881 cgtaggtgat atcactcact ctcgcgtagc taaatccaat atgcagatgt taaaacgtct
    38941 aggcgcacaa gtattcttct caggtcctag agaatggtac gacgatgaat tcgaagtgta
    39001 cggacattat atgccattgg atgaactact agatcaagtt gatgtcatga tgatgcttcg
    39061 ggtgcaacac gaacgccatg atggaaaaga aagtttctca aaagaaggct accatcagga
    39121 acatgggtta acagttgagc gtgcgaagaa gttgcaaaaa catgcaatca ttatgcaccc
    39181 agcaccagtt aaccgtgatg tagaattagc tgattcatta gtggaaggat tacagtcgcg
    39241 gatcgttcag caaatgagca atggagtatt cgtcagaatg gcaatcttag aagcagtgct
    39301 aaatggaaaa gcgtaattat aggaggatga aaaaatgaaa acactcatta aaaacggtca
    39361 gatcaataca cgaaaaaata tgacgacacc agcagaaatt tggatagaag atgggcgaat
    39421 caaagcaatc ggtacaggat tctcagaagc cgaatttgat gaagtgtttg atgcaaaggg
    39481 acaattgatc acacctggtt tagtggacgt ccatgttcat ttgagagagc caggatttac
    39541 atacaaggag acgatcgaag ctgggactcg ctcagctgct cgtggcggtt tcactactgt
    39601 atgcgcgatg ccgaatttaa atcctgtacc tgatacggca gaaaagctga gacaagtata
    39661 tgacatcatt agaaaagatg cagttgtgaa ggtattgcag tatgcgccaa tcacagaaaa
    39721 tctgcgaagt gagaaattag ttgatcaaga agcactgatt gaagaaggtg cttttgcttt
    39781 cacaaatgac ggtgtaggtg tccaaacagc tgggacgatg tatctggcta tgaaagaagc
    39841 tgcaaaaaac aataaagccc tagtagccca tacagaagat gaatctttat tatttggcgg
    39901 cgttatgcac gctggcaaga aggcagaaga acttggtctt cccgggatct taagcgtaac
    39961 cgagtcttct caaattgcta gagatctgtt gctagctgaa gcaactggtg ttcattacca
    40021 tgtttgccat gtttctacta aagaaagtgt ccgtgtaatc agagacgcaa aaaaagcagg
    40081 aatccacgta acagcagaag tttcacccca tcatcttatt ttgatcgacg aagatattcc
    40141 cgaagatttc ggcttttgga aaatgaaccc gccgctaaga ggacgggagg acagagaagc
    40201 tttgatcgaa ggcttgcttg acggtacgat cgattgcatc gctacagacc atgcccccca
    40261 tggattagaa gaaaaaagcc aaagtttcat gaaatcacca tttggtatcg taggaagcga
    40321 aacagcgttt caactgatct atactcattt tgtagaaact ggtcgattca cgttggaaca
    40381 agtgatcaat tggttggcag ttaaaccggc tgagattttt ggtttgaatg caggaacgct
    40441 aacggttggt gcccccgctg atgtagcagt ttttgatatt acacaaactt gcacgatcga
    40501 taaagaagac tttttatcaa aaggggagaa tacacctttt atcggctgga aagtaaaagg
    40561 cgaaacacaa atgacttttg tcaacggaaa acttgtgtgg cagaagggag aataaaagta
    40621 tggaacgttt gcttatatta gaagatggaa cagttttcga aggaaaggct tttggtgcag
    40681 atgctagtgt cttcggagaa atcgttttta caacaagtat gactggttat caagaaacta
    40741 tcactgatca aagttttaac ggtcaaatca ttacatttac ctatcctatg gtgggtaatt
    40801 atggggtaaa tagagatgat tatgaatcga tttctccaac atgcaaagga gtagtagtaa
    40861 aagaacatgc acgtgtagct tcaaactggc gaaaccaaat gacgctagat tcatttttga
    40921 aacaaaaagg aattcctgga atatcaggta tcgatacgcg cgcccttact cgcaaaatcc
    40981 gtgaagtcgg aacgatgaaa gctagtatag ttgatgctgg agattccttc gaacatgcat
    41041 ttgatcagct gaaagcaacc gttctagcaa ccaatcaagt gcagcaagtc tcaactaaca
    41101 aaccttatcc aagtccagga acaggtcgga aagtcattgt cattgacttc ggcttgaaac
    41161 atagtatttt acgagaattg agtaaaagaa actgtaacct cacagtactt ccctataaca
    41221 cagatgccga gacgatttta gcgctatcac cagacggagt catgctgacg aatggacctg
    41281 gtgatccaaa agatgtgcca gaagcaatcg aaatgatcaa aaaaatccaa ggaaaagtac
    41341 cgatttttgg tatttgtctc ggtcaccagt tatttgcttt agccaacggt gcagatacct
    41401 ataaaatgaa attcggacat cgaggattaa atcacccggt acgagaagta gcgaccggaa
    41461 gaattgattt tacttctcaa aatcatggct atgcagtcga tgaagccacg attgatccag
    41521 aaaaactcat cgtaactcat gtagaagtaa atgacggaac agtagaagga gtcaaacaca
    41581 gagattatcc cgctttcagt gtgcagtttc atccagatgc tgcccctggt ccgcatgatg
    41641 cactacattt atttgatgaa tttatggaaa tgatggacgc aggaaaggag cagtaaacag
    41701 atgccgaaac gtacagatat caagaaaatt atggtgattg gatctggtcc gatcatcatt
    41761 ggtcaagccg cagaatttga ctacgcagga acacaagcct gccttgcctt aaaagaagaa
    41821 ggatatgaag tggttttagt aaattctaat cctgcgacga tcatgacgga taaagaagtg
    41881 gcagatcaag tatatatcga accgatcaca cttgaatttg tatcaaggat tcttcgaaaa
    41941 gagcgtccag atgctctcct tccaacttta ggcggacaga caggcctcaa tatggcaatg
    42001 gagctggcag catcaggtat tttagaagaa ttgaacatag aacttctagg aacaaagctt
    42061 tctgcgatcg atcaagcaga agatcgtgat ctattcaaac agttgatgaa agaattgaat
    42121 cagccaatcc ccgagtctga aatcgtcaat acagtagaag aagctgtaga ttttgcaaat
    42181 aaaatcggct atcctgtcat cgttcgtcca gcctttactt taggcggaac tggtggaggt
    42241 atgtgtgaaa atgaagaaga attacgtatc gtatcagaaa atggattaag tctttccccc
    42301 gctacccaat gtttgattga acgaagtatt gcaggtttta aagaaattga atatgaagtg
    42361 atgagagatt cggctgataa tgcaatcgtt gtctgcaata tggaaaattt tgacccggtg
    42421 ggtatccata caggtgattc tatcgtattt gcccctagtc aaacattgtc tgaccatgaa
    42481 tatcaaatgc ttcgtgatgc ttctctttcg attattcgag cacttaagat cgagggaggc
    42541 tgtaatgtcc aactcgctct tgatccacat agttttaatt attatgtgat tgaagtcaat
    42601 ccgcgtgttt ctcgttcatc tgcgttagca agtaaggcga ctggctatcc gatcgctaag
    42661 ctagctgcta aaatagcgct tggattaaca ttagacgaaa tgaaaaatcc tgttacagga
    42721 acgacttttg cagaatttga acctgcatta gattatgttg tagctaaaat tcctcgctgg
    42781 ccgtttgata agtttgaaaa cggagaacgg cttttaggca cgcagatgaa agcaactggt
    42841 gaagtgatgg ctatcggtcg gaatatcgaa gagtctttat tgaaagctgt gcgttcttta
    42901 gaaatcggta cacaccatat cgaacttcct gagttggcag acatcacgga cgatgaccta
    42961 atccaaaaag tggttcgagc acaagatgat cgcctgtttt atgtagctga agctattaga
    43021 agagggtaca ccatagaaga attagcggat ttgacaaaaa tcgatttatt ctttttagat
    43081 aaactgttgc atatcgtaga aatcgaacag cagttgaaac agcagccgtt ggatgacaag
    43141 atattgaaaa cagcgaaaca aaacggtttt acagacaaaa aagtggcgga gctgtgggaa
    43201 ataaacgaag aagccgttcg ccagatgaga aaagaaaatg atttgattcc tgtatataag
    43261 atggttgaca cttgtgcagc ggaattcgaa tcaaaaacac cttattttta tagttcctat
    43321 gaatatgaaa atgaaagttc acgatcagaa aagccctcaa ttctagtact gggatctggt
    43381 cctatccgta tcggacaagg ggttgaattt gactatgcga ctgtgcattc tgtcaaagca
    43441 atccagcagg caggatacga agcaatcatc atgaacagca atcctgaaac agtttcgact
    43501 gacttttcta tttcggataa attatatttt gagccattga ccttcgaaga tgtgatgaat
    43561 gtgatcgagc tagaacagcc gataggagta atcgttcaat ttggtggtca gacagcaatc
    43621 aacttagccg aacctttgac tgctgctggt gtaaaaatct tagggacaac gatcgaagac
    43681 ttggatcgtg cggaaaatcg tgatttattc gagcaagcgc tgaaagagtt ggatattcct
    43741 caacctttag gggatactgc tacaagtaaa gaagaagccg tggttatcgc ttcgagaatt
    43801 ggttatccag ttcttgttcg tccaagctat gtattaggcg gacgtgcgat ggaaatcgtt
    43861 gaaaaccagc gagatttaga agattacatg gaacatgctg tgaaagcatc tccagaacat
    43921 ccagtactag tggaccgtta cttgcttggt ggtgaatgcg aagtggatgc gatttgtgac
    43981 ggtgaaacag tactcatccc agggatcatg gagcatattg agcgtgctgg tgtccattca
    44041 ggggattcaa tggctgtgta tccacctcaa acattatctg aatcgatcaa gaaaacgatc
    44101 gaagattaca cgatccgctt agcattaggt ttgaattgtg tcgggatgat gaatatccag
    44161 tttgtcatcc atgaaaatga ggtttatgtg atcgaagtca atcctcgagc aagtcggact
    44221 gttccattct taagtaaggt gacaggaatt ccaatggcac aaattgcgac gaaagctatt
    44281 ttgggagaga aactaaagac acttggttat gaaaacggac tttatccaga aacaaaagaa
    44341 gttcatgtta aagcacctgt cttttctttt acgaaattgc agaaagttga tacttactta
    44401 gggcctgaaa tgaaatcgac tggagaagta atgggatctg acagacaatt agacaaagct
    44461 ttgtacaagg cattcgaagc ttctggatta cacttgcctg aatatggagc cgtattattt
    44521 acgattgcgg acgaaacaaa agaagaagca ctagaattag ctaaacgttt tacagaaatt
    44581 ggctatagtc tgataggaac gaaacataca gctgcttatt tcgaaaaaaa tggtctggtc
    44641 gttgaaacag tagcgaaaat ttctgaggaa gcagcagaaa aaaatgtagt cgacttaata
    44701 agagatggta aaacacaagt ggttgtcaat acgattgata aagatcgggg aaatgcttct
    44761 aaagacggtt tcatcatccg aagagaagca gttgaacatg gtattccatt gtttacttct
    44821 ttagacacag cagatgcgat cgttcgagtg atggaatccc gtgctttttc aactaaccct
    44881 atttaacggc gagcacatgt taagacaaaa agacgaaaaa ccgttgcagg aggggacaga
    44941 tgaaacaaga aatgatggaa atcgttcagc aaaaacagct ggcaccaaag atttttgaaa
    45001 tgacattgaa aggtgatcta gtaaaagaaa tgcagcaacc aggacagttc ttgcatattc
    45061 tcgtgccgcg tgcagacttg ctattacgcc gaccgattag cttgaatcat atcgaccacg
    45121 aaacaaatac ttgccgtatc atttatcggg tggaaggtga ggggactaga gtcttctcta
    45181 ctctttctgc cggagaccat ttagatgtca tgggtccttt aggcaatggt tttgatttgt
    45241 ccaatcttca tacaggagac gaagtattta taatcggtgg aggaatcggt gtccctcctc
    45301 tatatgagtt atcaaaacag ttagtcgaaa aaggaattaa gccaacgcat tttttaggtt
    45361 ttgccacaca tgaagtcgtt tattatgaaa aagaatttaa tcgtctagga gaaacaagaa
    45421 tcgctactga cgatggaaca tacggtatgc acggaaatgt cggtaattta ttgttaggaa
    45481 cgaagacgga acctacagct gtttttgcat gtggttcaaa cgggttattg aagacagtgg
    45541 aacagctgtt ttcttcgcat caaaatgtcc agttatcatt agaatcccgc atggcatgtg
    45601 ggataggggc ttgctatgct tgcgtttgtc atacgccgga agatgaaaca ggaacaaaaa
    45661 gtgtgaaagt ttgtgacgaa ggaccgattt ttaaaatagg agaggtaatt atatgaatga
    45721 gaatccttta gcggtcaaac ttcctggcct agaattaaaa aatcctatca tgccggcaag
    45781 cggctgtttc ggttttggca aagaatacgg aaaatactat gatttgaatc agcttggatc
    45841 gatcatggtc aaggcaacga ctccaaatgc ccgctttggc aatcccacgc caagagtggc
    45901 ggaaacacca tctggcatgt tgaatgcaat tggtttgcaa aatcctggtc tagacgttgt
    45961 tatgcataaa cttcttccag aattagagga gtacaatgag ttacccatca tcgcaaatgt
    46021 tgctggtgct tgtgaagaag actatgtaga agtttgtagc aaaattggcg aagcaccaaa
    46081 tgtgaaagca atcgagctga acatttcttg cccaaatgtc aaacatggcg gaattgcttt
    46141 tggaacagat tctgatgttg cttttcaatt aacacaagca gtaaagaaag tttcttctgt
    46201 tcctgtctat gtcaaattgt ccccaaatgt aacagacatc gttccaatcg ctcaggcaat
    46261 cgaagctgga ggggcagatg ggtttacgat gatcaatact cttcttggta tgcggattga
    46321 ccttaagaca agaaaaccga ttttagccaa tcaaacaggt ggactctccg gaccagcaat
    46381 caagcctgtc gctattcgtt tgattcacca agtagcaagt atatccagcc ttccaatcat
    46441 tgggatgggc ggcgtgcaga cagtggatga tgttcttgag atgtttatgg ctggagcaag
    46501 tgctgtagct atagggaccg cgaatttcac cgatccgtat atctgtccta aactaattaa
    46561 agagctccct gtgcgaatga gcgaactagg catcgaatcg ctggaaagat taatcaaaga
    46621 agtgagagag gaacgtgaac gatgaatcaa ctagaccaac gaccaattat tgcattagat
    46681 ttttcaacta ggcaagaggt agaagacttt cttcgatttt tcccgaaaga agaaaaattg
    46741 tttgtgaaaa tcggaatgga attgttctac caagaaggac ctgaaatcgt acgttatcta
    46801 aaagaggctg gtcataatgt atttttagat ctgaaacttc acgatattcc gaatacggtc
    46861 gaaaaagcaa tgcggggatt ggcaaagctt ggtgttgatc tcacctgtgt tcatgccgct
    46921 ggcggtattc gtatgatgga ggcggcaatg cgaggattag aagaggggac tccagaaggt
    46981 ggaaaacgtc cgctacttct agctatcact cagcttactt ctacaagtga agaagaaatg
    47041 catgccgatc aactaatcga agtttcttta gaaaaaagtg tgatccatta tgctagctgt
    47101 gccaaaaaag caggattaga tggtgtggtt tcttctgctt gggaagtaga agcgatcaaa
    47161 gaaatggcag gagacgaatt tgtttgctta actccgggta taagaccaga aggaacagtc
    47221 gcaggagatc agacaagagt agtcacacct tctcaggcaa aaaagatcgg ctcaactttt
    47281 atcgttatag gtcgaccaat cactcagtca actaatcctt ataaagcata tcaaacgatt
    47341 caaacagaat ggagctaacc taaaatgaat gttgaacaaa gtatcgcaaa agacttatta
    47401 gaaattgaag cagtattttt aaatccaagt aatcctttta catgggcaag tggaatcaaa
    47461 agcccaattt actgtgataa ccgaatcacg atgagctatc caaaagtccg aaaagagatc
    47521 gcaaaaggat tagcaagcaa aatcaaagaa gcttaccctg aagtacaagt gattgctgga
    47581 actgcaacag caggaatccc tcatgccgca tgggtagcgg aaatactgga tttgccaatg
    47641 gtctatattc gaagtaaggc gaaagatcat gggaaaggta accaaatcga aggacgtata
    47701 tttgaaggtc agaagatggt tgtgatcgag gatttgattt ctacaggcgg aagtgtcttg
    47761 gaagcagctg aagcagcaaa aagagaaggt gcggatatcc ttggtgttgc ggctatcttt
    47821 acgtatgagt tgccaaaagg aaaagcaaat ttcgaaaaag ccgaaatccc tcttatgacg
    47881 ttgaccaatt attctgtatt gattgaagca gctttagaag atcgttatat cgatgagcaa
    47941 gaattaactc tgctaaaaga atggaaaaaa gatcctgaaa attggcagat ttaagcgcgc
    48001 ttgatgaaga tagagaaatc cgatttgtgt ctccagaatc atcaattgga atagcaaaaa
    48061 tccaaaaact gattgcgaga agcatctttt catcaggtat gaaaagaaac ttctatcgtg
    48121 atcagttttt gattttttta aaattcattt ttctaagact ggttagcaga aagaagagaa
    48181 taatctcttc tcttttttct attatatata gattttctct attttttggt aagggagctg
    48241 tttcaaaaat ggtaaagagc ggaaatgttg cgaatatcag ttatttaatg atatgatatt
    48301 cggaaaaaga aatctcaaag ggaggtaact tttatggggt tgaatgaatt tattttagga
    48361 ttgaacaatt tagagacgat cacaagggca cctggatttt ttaaatatac agagcataca
    48421 gttgcagcac attcgtatcg tgtagcatct attgcgcaag ttctaggaga cattgaagaa
    48481 gcgaatggac aaccgatcga ttggaaactg ctctatgaaa aatcattgaa tcatgactac
    48541 acagagcgtt ttattggtga tatcaaaacg ccggtgaaat acgcaagcaa agagttaaga
    48601 gggatgctgc aaacagttga agaaaagatg acggacgaat tcatcaacca agagattcca
    48661 gctgagttcc aagaagttta tcgccgtcgg ttgttcgaag gaaaagatga aaccgtagaa
    48721 ggagaactat tagccatttc agataaggtt gaccttcttt atgaatcttt tgatgaaatc
    48781 atcaaaaata acccggaaaa agtttataag gagatgttca ttgaggcagt gactacgatt
    48841 aaaagctttg aacatcggcc ttctgttcag tatttcttta aagagatatt tccggaacta
    48901 ttgaaccagg aattttatgg aaaagaggcg tttttagaaa ccgtctcaac gattgtaaag
    48961 aaagaagaaa aataaaaatg atatgagatg cagggggaag tatagttgaa aaagaatatg
    49021 gatgtcgaat ggggctattc tggagacaaa ggtccggaaa attgggcgag tttatgtgat
    49081 tggtttgcga gaggtgcgga atttccattg cagtcgccta ttcatttgac caagggggaa
    49141 gaaaccaaaa tagaaggaga cacgctttcc tttcattatc aaaagcaacg gtttactgac
    49201 aaggaattca aaaacacgat tcatttagta ccttttgacc aactcagtta tgtagagttc
    49261 aagaaagaac gctattattt gacagatatt catttccact tgccttctga acatatcatc
    49321 aacggaaaac aggaagatat tgaatttcat tttgttcata tgaacagcaa aaaagagaat
    49381 ctagttgtgg gtgtcatgta ccagctaatg gtacaggaag gttggctgta taatcaagaa
    49441 aatggggaaa gttggaactt agaaaaacat gagcattggg taaatccgga tgtgttcttt
    49501 ccggagcaaa aaagccattt ccattatatt ggctcattga caactccgcc taccagcggg
    49561 ccaatccaat ggtttgtaat ggatcatgta ggaaaactga accaagagtt tcttctcccc
    49621 ttcgatggtc agtatgctcg accgaacaac cgaccaatcc agcccttgaa tggaagagaa
    49681 atttattatt tcgaggagtt tgagcaatga atattcagca gatgaaatac gtggtcgctg
    49741 tagcaaacaa tggtagtttc agagaagcgg caaagaaaat gtttgtctcc cagccaagtc
    49801 tttcagctgg tatcaaagaa ttagaaaccg agttagggat cacgctgttt actcgaacga
    49861 atcgaggggc atatttaaca gaagaagggc aagacttctt aaatcgtgcc gagaaaatat
    49921 tggtccagct tgatacatta gaaactcact atctaacgag tgaaaagaga gacaattttt
    49981 cgatcgctgc ccagcattat gatttcttag gtcctttgac cgcacagcta ctcgaggaat
    50041 tcaaagacga gatcaaacaa tttcggatca tggagacgac aacagcgaga gtgatcgaag
    50101 aagtcaaaga gcagcacagt gagatcggca ttatttatat gaatgagcat aatcaagctg
    50161 gtatcagaag atatttacaa caaggagagc taagtggccg cagcattgga aaattcaaaa
    50221 cgcatatttt tttaaggcaa ggacatccat tagctgaaca cgcagagatc accaaagaag
    50281 aattgttatc ttatcctcaa gttcgtttta cacaggatgg aaataatttc ccgtattttt
    50341 atgaagacct tatcgagatc cctgatcaag aaacagtgat ttatacgagt gatcgaggta
    50401 ctttgatgaa tatcgttctt gaaactgatg cttacgcttc aggatctggt attgtgattg
    50461 gagggattcg cgagcacttg cggttaatcc ctttggcaga aggcgaacta aatgaatttt
    50521 atatcattta ttcggcgaaa cgtccgctca gtgaaatcgc tcaaagattt atcaaagagc
    50581 ttactcggtt actggaccag cagagctaag aaaagcagat gagaacgctg tttattgaac
    50641 accgttgatc aaaaaagagg ggttgtgaca gaattttgtc acaactcctc tttttgtagc
    50701 aaacaattta taactaattg ctgttgtggg aaagtacgca aatatgattc tagaaacact
    50761 cattgattac ctgttttgtt tcatagctgt aattttttct tcttctggtg tcacgataat
    50821 cgtcttttgg ttttcataaa taacataacc aggcttggcg ccatttggtt ttcggatatg
    50881 ctttacctgt acaagatcaa ccggcacttg ggcagagtat cggtattttg aaaaataggc
    50941 agctaactcg gcagcttctg taattgtttc atctgagggc ttgtcacttt taatgatgac
    51001 gtgcgaaccg ggtatatttt ttgcatgaag ccaatagtcg gtttttttag ctgtcttcat
    51061 tgtcagctgg tcattttgaa gattgttttt accaacaaga atgagcgttc cgtcagaaga
    51121 aaagtattga tcaggctgag atggtttctt acgtttttgt ttttttaagt tcttcttttt
    51181 caggtatcct tctgaagtca attcttcttt aattgcttcg atatccattg ggccggcaat
    51241 ttccagttga gataagacag attcaagata ttggatttca tctttggctt cttggatttg
    51301 ttcgccaatc agcttaacag cgttcttcag cttttggtat cgatggaaat atttctgtgc
    51361 attttgattt ggtgtcaatg ccggatctag tgctattttg attggccgat cttcttcata
    51421 ataattaggt aaaacaactt cttttgcgcc gcgtggtact tgtgtcagaa aagtagtaag
    51481 tagttcgcca tttctacggt aattctcagc gttttcggat tctttgagtg tttgttcacg
    51541 ttttttcaat ttatttttat ttcgttttag ttcattttcg atttttcgaa tcagttctcc
    51601 gccttgttgt tttgcccgat ctttctctgc tttttcgtga taatagctat ctaataattg
    51661 actgagtgtt ggataagctg ttacagcaga tgcctgttcg gacaatacct gataagcaat
    51721 cggtgtgaaa aaatctttat tttccgtttc gtaaaaagta ggaataggct gatggctgat
    51781 ggctgagaaa aattcgtccc atacaaccat cttttcatta ggacgttcca gtaatctttt
    51841 ggtcagctct tgagcgatat cgaaaccgat tccctgaaac tgacgttgga ttgcttttgg
    51901 atctagttca gtttgggaaa gccgctgaaa gattttttct ttctcggagc taaatgggtt
    51961 caagacctct tgttttggcg gagcaacata ttctacacca ggaagcaaag aacgataagt
    52021 gttttgagag cttccaatgt gtttgatcgc atccagtatt tttccagttt ctcgattaac
    52081 taagacgatc gtactatgac gtcccattaa ttcaacgatc aatatgatat tttgtagatc
    52141 acccaactcg tttcgtttag caaagtggaa atggatcact cgatcatttt cgatttgttc
    52201 gatgtcttct aaaatagcgc catccaaata ttttcgaagc atcatcacga agttaggcgg
    52261 attatcagga ttctgataat cgatttgggt aatctgtaca cgagcataac ttgggtgcgc
    52321 agataataat aatcgatggt ttttgccgcg tgaacgaatc accagcacga tttcattttc
    52381 ataaggctga tggattttcg agatccggcc agatagtaac gtttcacgca attcgttgac
    52441 catcgcgtgg gtaaatacac catcaaagga catggttcat tcctcatttc ttttcataag
    52501 tatattcatt ataacgaaaa aaagaagaaa aaccaatttg gccgaatagt aaagcaaaag
    52561 tctagaaaaa tcttggacta attacataaa aaacagtgtt tctatcgttg aaatccaaat
    52621 ttttaggtat aataaaaaat aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa
    52681 gtagttaaat cgagagtaca agaaatgaat gaacatttct cagtgtcatt cgcagaaaat
    52741 ccaagtaagt attttcgacg tcttgttttt ctgctcatct tatcattgct gttaacagtt
    52801 gcaatgtttt tattgccgga aaaaatccga gaagagcaag taaatagtct cgtttattcg
    52861 tccataccaa ccagcaaatt gaaacctttt gattacagca aagctgatca gaaaatcaaa
    52921 caaagccggg cgatatcggt gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg
    52981 cttgatgttt ttaatgatcc tgagcttatg gaagaattga atcgaccgat cttttattat
    53041 ccgatcgttt atgatgtaca tgaactggaa caaaaatata acatacgaac ggatgaagtg
    53101 acatttattt tctttgatgg aggaaaagaa gcaaatcgga taactgcggg taagggagga
    53161 ataactgatt ttgataagga gttgatccct gaactgaatc gacttccgtt agccaatatc
    53221 aaacaattag aagaagaatt ggatagaacg ggagtaactt cccaaaattc cgagattgct
    53281 aattgagaca ttggcgcgat gaaacggtgg gtctatatag cgctattttt aattatcaga
    53341 acaagtgatg tttgatcttc aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa
    53401 ttcaaaaatt cgatttgact taaatcaatt cttaaggaaa gggtgacctg taatgaactt
    53461 atcaaaacgt atttcagcag aaaacaaaaa aaattggcgc agctggcgta gataagttgt
    53521 attaatggtg agactttccc atagatacaa ctttttagag tgcatttcta aagcttgtat
    53581 ctatgctaga catgaacatt gactgccgca tagattagaa tctatgcggt tttttgtgta
    53641 aagacaatga ccgctttggc cattgtcttt ttttgtagac tggatacttg cctgattata
    53701 ataaataaaa agattgactt tgcaggagga aaaaaatgaa aaacaaacga ttaataacag
    53761 ttgtagtaat tattttagtt tatttagcag gtgcatttat ttatggaaaa gcctcaggcg
    53821 aaaaagaaag tacttcgacg aaccagacaa aaaaaacaac agttgttggg gtattgcaat
    53881 acgtgagcca tccggcatta gatgagattt atcgaggaat caaagatggt ctgaaagaag
    53941 aaggattaaa agaaggagaa aatcttgaga tcaaatttca aaatggacaa gccgatcaga
    54001 gcaagctagc cacaatgagt caacagctag tacaatctga tccagatgcc ttgattggaa
    54061 tcgcaacacc tgccgctcaa tcattagcaa acacgacttc atcgatccca gttgtgttag
    54121 gtgctgtaac ggatcctgtg ggggctggat tagtcgcttc tttagagaaa cctggtggta
    54181 atgtaacagg tgtttctgat cagccgcctg ttacttcaca aatcaagctt gcttctgatt
    54241 tgttgccaaa tgcaaaaaaa gtcggaatct tgtatgcttc ttcagaggat aattcaaaat
    54301 accaagtagc acaagcagaa gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg
    54361 cggtgccttc cactaatgag attgcacaaa cggttcaagt gatgagccga caagtcgatt
    54421 ttatctatgt tccattagat aataccattg ccaatgcgat gcaaacagtg gtaaaagaag
    54481 caaacaaagc aaatatcccc gtcattccat ctgtggatac aatggtggaa caaggtggac
    54541 tagcaacaat cgggatcaat caatatcaat tagggcttca aagcggtaag atggcggcag
    54601 aacttgcgag tggaaaagaa aaaccggaaa cgacgcctgt ttatacattt gatcaagggg
    54661 atacagtgat caatcaatct caagctgatc gcttaggaat cattgttccc caatcgatga
    54721 aggaaaaagc caaaatcatt acagatgact cgcagcaaga aacatctaag gaggatgaca
    54781 aatgatcgta tcagctattt cacaaggcat gctttgggca atattaggat tagggatttt
    54841 catgacttat cggatcttag actttcctga tatgacgaca gaagggtcct tcccattagg
    54901 tgctgctgtc tgtgtgacag ctattactca tggggtagcg ccgattgtag ctacattatt
    54961 aggcgtaggt gctggcatga tagcaggact cgttacgggg ttactttata caaaaggaaa
    55021 gataccggtt attttagcag ggattttagt gatgtcagga ttgaactcag ttattttgtt
    55081 tgtgatgcga acaccaaatc tttctttatt gaatcatccg attctacaag acagcttcca
    55141 tcgctttggg ttacctgatt actttgacac agtccttctt ggcttcatct ctttgggcat
    55201 cttgattgct gtactgctat tcttcttcaa tacagatttg ggtcaaggct atattgcgac
    55261 aggagacaac gaaacgatgg ctcggtcgtt agggataaaa accgatcgta tgaaaatttt
    55321 aggtttaact ttgtcgaacg gtgtcattgc attatccggt gcgctgattg cccagaacga
    55381 cggatatgca gatgtaaata aagggattgg cgtaatcgtc atcggtcttg cttccatcat
    55441 catcggtgaa gtgatcttcc aagaattgac gctagcagaa agattgattg ctattgttgt
    55501 cggcagtatc atttatcagc tattgatttt agtagtaatc aaactagggt ttgacacgac
    55561 ttatctgaag ttgttctccg ctatcatctt agctatttgt ctgatgatcc cgcaattgaa
    55621 gaaagcactg aacttaaaaa cgggttttga gaaggaggca tagtaatgac tgatatattg
    55681 acaatcaaaa atggcagaaa agtcgtaaac aatggaatga atgaagagaa agtactattg
    55741 gatgaaatta accttacaat cagagaaggg gacttcatca ctgtccttgg cgggaatggt
    55801 gctggaaaaa gcacactgtt caatacgatc gctggtacgc ttcaactcag tcaaggatcg
    55861 atctctttta aagatcagct gatcacaaaa gattcagaag aaaaaagagc acgattcctt
    55921 tctcgagttt tccaagaccc caagatggga acggctcctc ggatgacagt agcagaaaat
    55981 ttgctacttg cacaaaaaag aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat
    56041 caaaaagaag attttttcag actatgtcaa gaagtcggta atggcctaga gcaacacttg
    56101 gatactccag cgggtgaatt atctggtggt caacgccaag cattaagctt gctgatggcg
    56161 acgatcacag ctcctgagtt actattatta gatgaacata ctgcagcttt agatcctaaa
    56221 acagctaaag cattaatgcg attaacaaat cagcggatca atgaacaaaa attgacttgt
    56281 ctcatgatca cgcatcgaat ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc
    56341 caaaaaggga aaatcgttca agatatttct gaaaaagaaa agcaacattt gacaatgggc
    56401 gaccttttgc agttctttga agaagtagtg gattgatttc gacagaaaaa ttcctttcag
    56461 tagaaggact tgaaaactca ttgacatctt cctttgattc atcctatact taaaacaata
    56521 aacaattaaa catatttggg tgttttgtag gatcacgtag tcaatgattt taacaattaa
    56581 atagaatatt ctttgctctg acaagtaaac gatgagaaaa gaatttgcta ctttgccacc
    56641 tagacgtttc gtactttttc gtatcaaacg ctaagtggct ttttttattg aagtaagaac
    56701 aaaggaggaa taagatgatt tctggacaaa ccaaattagc tgggctcttt gctgatccgg
    56761 cttctcacag tttatcccca ttgatgcaca atactgcttt tgaagcaaac aacatcgatg
    56821 cggtgtattt agctttccaa gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc
    56881 gaacttttga tatgttaggt gtaaatcttt cgatgccgaa taaaacagcg gttattcctt
    56941 atctggatga ggtaagccag gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg
    57001 aaaagggtcg tttgattggc tataatactg atggtgcggg cttcatgcaa tccgtgcaag
    57061 aagctgggat ttcgatcaaa aagaaaaaaa tgactctact gggagctgga ggtgcagcaa
    57121 aggcagtcac tgttcaagca gcgttagacg gcgctgagga aatcgtagtt tataaacgaa
    57181 acaaccaaac attcgctcaa gtaaaagaaa cattcgaaca actcagctat cgaacttctt
    57241 gtaagataaa agttcgtgac tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa
    57301 gctgtcttct agtcaatgca acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc
    57361 tcttagatat aagcatgatg catgagaatc tagcggtttt tgatttgatt tatgcaccta
    57421 gagaaacacg tttattaaaa gaagcaaaaa aagtaggagc aaaaggatac aatggacttg
    57481 gcatgttgat ctaccaagga gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga
    57541 tccatgtgat tgaaaagctg tttgattaaa aaaggataat agataaagat cttttattct
    57601 cgcataaacg gtctcaagaa aagtaatcct ttatgtatcg aagcatttat ttcgttattt
    57661 tttattaaat tatcaaaaaa tgataggctt ttgtcgattg gttatcgtat cctttattta
    57721 tcagtaagaa acgaggagga accacaatga gtcggatgga tcgctataag gacatccata
    57781 agaaggcgaa acctctgaag cgggatacgg ggagtatttt tgctagaaga gaacgaaaac
    57841 gaacgcgtat ggaaaatgag gaagatgcta cccgtattta tgaaagagag cagcattcat
    57901 ttgaacattt gaaccaatac gagcaacaga tatacagaga tgcaccaaga gcagaagaac
    57961 aacaaaaaaa taaaaaattt ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa
    58021 gaaagcgatc gtggaaaaaa atcattctat cgattttgct tgttttgatc ctttattcag
    58081 gtatctcatt ttttattggt aaatatgtag ctgaacatga cacaagctta gaggcagcga
    58141 cttcagaaac ctttcatggg caaaaagcga cgaatggtgc gcataatatt ttgatccttg
    58201 gaagtgatac acgcggagaa gatgccgggc gagccgatac gatcatggtc ttacagttgg
    58261 atggtccttc ccataagccg aaactgattt cttttatgcg tgacagcttc gttacgatcc
    58321 caggggtagg acaaaataag atcaattcag cttatgcata cggaggagcc gatctagtgc
    58381 gtcaaacttt agtagaaaat tttggaatcg attgtcaata ctatgcgaaa gtcgatttca
    58441 aatcgtttga aaaagtgatc gatgccttat tcatgaacgg agtgaagatc gatgcagaaa
    58501 aagatctgaa tctggatggt gtagatatta aaaaaggggg ccagaagatg gatggacatg
    58561 ttcttttgca gtacgcacgt ttccgaatgg atgaacaagg agactttggc cgtgtcagac
    58621 gccaacagca agtaatgaac gctattttca gccaattgaa gaatccattg aatctgatcc
    58681 gtgcacctta tgcagctggt aaagctttag gatatacatc cacagatgtc actgcttggt
    58741 tcttgacgaa aaacctcttt tcgattgcac gaggagctgg tggcattgat cgaataagtg
    58801 tgccagtaga cggttcgtgg aattatgggc aaagtgatta tgctggcagt attcttgaaa
    58861 ttgataatca aatgaatcaa tctgctatta cagatttttt gaataaatga tcataaaaaa
    58921 gatcaagaag aagctgcgca aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa
    58981 aaacgctttc ttatggtaga tttaaccaag agaggagctg tttacattgg atatctatct
    59041 gaacttcaaa aatgagtcgc gtgaagccat cgctttttat gaaaaagttt ttcagactga
    59101 agcatcaggt atcaccacat acggtgaaat gcctggaata gaacaaatga acttgccaga
    59161 agaagcaaaa aatctaatca cgaatgcacg gctgaacatt tatgatacat tagttatgtt
    59221 tgcagatacg ccagaaggaa ttggtcctga attagttgtg ggaaataatg tttctttagt
    59281 catccagaca agaaatgaag aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg
    59341 taagattgag atgccactgg atgctgttcc gtgggctcag ttgtatggga tggtaactga
    59401 tcgatttggc atcaactggc agattaacca agagtgacag ctaaagatga atattttctg
    59461 gaaacatcaa gcagcaaacg gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg
    59521 actatacggt atcttttttt tattgccaga tgcgaaaata tgttccataa tagagaagtc
    59581 cgcaaaaaat taagtaacgg aggtcagaag atgaagacgg tgatactagc tgaaaaacct
    59641 tcacaagcaa aagcctatgc cgaaaccttc caacagcaaa agcggcatga agggtattat
    59701 gaaatcagcg atccattgtt tgctggtgaa gtaaccatca cttatggttt tggacatttg
    59761 gtagatatgg ttgctccagg agcttatgaa gagcgttggg caaaatggtc tttagaaaat
    59821 ttgcctattt tcccagaaac cttccgttac gaagttccaa tggacaaacg tgcacaattt
    59881 tcgatcgtaa aacgagaatt gcagtcagcc gataccatca ttattgcaac agatggtgat
    59941 cgagaaggtg aagccatcgc gtggtcgatt attcgacaag caaacgcatt ttctaaggaa
    60001 aagaactatt tacgtttatg gatcaattct cttgaaaaag aagcaatcta tgaaggtttt
    60061 aagaatctcc aacctggaaa gaactatttt ccaaaatata aagaagcgca agcaaggcag
    60121 aacgctgatt ggctgattgg aatgaatgga agtccattat atagcttgct acttcaacga
    60181 aaagggattg atggcagttt ttctcttggt cgtgtacaaa caccgacact ctatatgatt
    60241 tatcagctgc aagaagaaat caaacacttc aaaaaagaaa cgtactttga aggagaaggt
    60301 ttaattacga caaacaaagg gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa
    60361 acccaagaag agttaacgaa ggaaatagaa aaacttggag cgcatttagg taagcaaaac
    60421 ggacggattc ttgaagttac gaaaaaggaa aagaggttgc atagtccacg tttattttcg
    60481 ctatctagtt tgcagacaaa gatgaatcag ctaatgaaag caagtgccaa agctacactt
    60541 gatgctgctc aaggattgta cgaaagcaag tttctaagct atccaagaac ggattccttt
    60601 tacattacag aaaatgagca tcagtatctg gttaaacatc tgcaaaatta taaaaaattt
    60661 ttaggaatag aagaagtaca gacaactgag atcaaagcaa agaaacgata tgtcgatgcg
    60721 aaaaaagttc aagaacatca tgcaattatt ccgacaaaga cgattccgac tcctgcacgc
    60781 tttgcgaagc tttccaaatt acagcaagca atctatttgc aagttttgcg cactactgtg
    60841 gctatgtttg ctgcagatta tatctacgaa gagacgaccg taatgacggg cgtacagcaa
    60901 ttaaagctaa aaagcatcgg aaagatccca ttacagcaag gttggcagga aatcttacgc
    60961 atcaagtcaa aaaagaaaga agctcagact cttcctccta tcgtagaaaa tgaagaagca
    61021 gaagtagaac tgaaaagtat ggagaaagaa acacaacctc caaaacccta taccgaagga
    61081 acgttgatca cagcaatgaa aactgcggga aaaacgctgg ataatgatga agcgcaagaa
    61141 attctcaaag aagtagaagg aatagggaca gaagctacac gagccaatat cattgaaaat
    61201 cttaagcaga agcattacat cgaagtcaat aaaaacgaaa taactgttac gccaaaagga
    61261 atcactcttt gtaaggcagt agccaatgaa ccattactga cgagcgcaga aatgactgcg
    61321 cgctgggaag ggtacttgag aaaaattggt aaacaagagg ggacaccatc tgttttttta
    61381 gagaatatca aaaaattcat cctacattta ttggcagaag ttcctaatca aatcgacaag
    61441 gtagactttt cagatgagat tagcgggaca cgtcagataa aagcgatgga gaagaaaaac
    61501 gatcaattag gaagatgtcc aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc
    61561 gctacatgct tgaatccgga atgcgacttc aaattgtggc caacagtagc taaaaagaag
    61621 ctgactaaaa cgaatctcag agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa
    61681 ggttttactg gtaaaaaagg gaaattcgat gcagttttag tattaaaaga agatatgaca
    61741 atcggttttt cttttccatg gatcgaaaac agtggaacaa aagcagttga tggaaacaaa
    61801 gaaacatcaa gaaaaaataa tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg
    61861 aatatttatt ccgaaaagtg agaatataaa taccaataaa actaaaaaat atcagtgaat
    61921 caagcaaaaa cgttggggta ggctgatttt atatagatag caaggagttt ttttatttga
    61981 aaaaagtgca ttcattttta aattatctta tgggagcaat cacgattgtg gctgtgtacc
    62041 aagcatttct aaagtatcct gattacggga cgaagttgtt gtcattgacg cacaatcaaa
    62101 cagcatattc accaacgttg attttatcga ctttgactgc aggagctaaa agcgctactt
    62161 atttttttca taaaacgaca agcatgctaa agcgaaagaa acagcgaaaa caattgttgg
    62221 tggtggtagc ggctatgatc attatttatt ttctaccagt tattacacaa gtatttcatc
    62281 aatattttgg ttaagaatac gagagtttgt gacaaaagtc atgtcacaaa cttttttctt
    62341 tgtcattttt tcgtaagaaa aagcaaaata aaagtatata cattgattaa aagtatatac
    62401 ttggatataa tgtacttact atagaatgag aatggtatag agggtggcga aatatgaaaa
    62461 aaatgaaaaa gtataaaatt agaaaatctg gcaatagcga tgtaacaact atcccaccag
    62521 aagtaaaaga attcatgggt gtgcagacag gtgacgcaat cagttatgtt tttcaatctg
    62581 atggttctgt acgaatgatc aaagcacaag aagaacctga tattgattca ttagttgatt
    62641 cgatcatgaa tcaatatgaa gacgcgttaa aagatttggt tgatttatga ggtatctttc
    62701 gactaaagaa attatcaaaa tcaacgcgaa agttatttta cgtcactcgc caggcgaaat
    62761 gatcggtgta aaagatgcaa atgcattaga tatggccgtc aaacagcctt cacaagcagt
    62821 attcaatcaa gaactctatc ctgaaatcta tgaaaaagcg gcgattttag caattaattt
    62881 agctaaaaaa catccttttc ataatggcaa taaacgaact gctcttgttg ccatgttgtt
    62941 gtttcttcaa ttgaataatt gtccagttgc tttttctcgt caagaagctg ttgattttat
    63001 cataatgatt accactagtt cattggattt cgattcacta aagtccaaga taaccagtta
    63061 tttacgacaa accgcaataa aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc
    63121 atgtcattaa ggaatatgct gattttttta tgtttaatca tacaaaatag ttttttcata
    63181 aaaatatgga aaatatggat taattttgaa ataattgatt taaaaggaat acaaaagagt
    63241 gaatagtagg aaatagtggt ttagaactag tgggctgatt ttttatatat tttagtttac
    63301 ataatatata ttatacaaag tagatttaaa aaatgataaa cctctctcga acggtttttt
    63361 atcaaaaatc gtcatttttc catcaaaatc tgcttatgca aaattataaa aaaattttgc
    63421 agtttttctt actttttttg tcgtttaatt gaatgataaa aaccagtttc tttattcagt
    63481 taatcaaata tgaacgaatt agatatgaat cattgtattt gccgttgcgg aaggattttt
    63541 taattaacca cagataaaca ttgataacga ttcgcttatt gtaatcaaca gattaaattt
    63601 catatgttca tatgtacgga tacattttcg gaccgattaa ttttaaccat tctgtttatt
    63661 tgcttaccta ttagatatca ataaaaaact gcttaacagc tatttcagct gttaagcagt
    63721 tttaggattt ttagttcata ttcattgttt cttataatac agtgttcaat acttctctta
    63781 aagcacttgt tgatttgctg aacattgctt tttcttcttc gttgattgat aattcaacaa
    63841 cttcacgaac accattttcg tcaacgattg atggcacacc tgtaaagata tctttttcgt
    63901 cgtattcacc agttaaataa gcagatacag gcaatacagc ttgttcgtta ttcaagatag
    63961 cttttacgat acgtgcagta ctcataccaa taccatagta agttgctttt ttacgatcaa
    64021 tgatctcata agcagcatta cggactttat cagcaatcac atctaattca tcttgggcaa
    64081 tacgatggtc tttttctaca atttcaaaca ctggtttacc accgacagtt gtatgtgacc
    64141 atgcagcaac ttctgaatca ccatgttcac ctaagatata gccgtggacg ctgcgtgggt
    64201 caacttttaa tttcaatgcg atttctttac ggaaacgagt tgtatccaat gttgttccag
    64261 taccgataac acgtgatgtt ggcagaccag attcgttcca agcgatatat gtcaaaatat
    64321 ctactgggtt tgaagcaaca acgataatac cgtcgaatcc tgatcccatg atttctttta
    64381 cgatttggcg catgattgac gcatttgttt taactaaatc taaacgagat tgaccaggtt
    64441 tttggttgat accagctgtg ataacaacga tatcagcatc tttacattct tcatagccac
    64501 ctgaccatac agccacattt tcatcgcccc aagccatacc atctaaaagg tccaatgctt
    64561 ccccttctgc tttttcttga ttcacatcga tcaatactaa ttcattagag attccttggt
    64621 tgatcattgc ataagcgata cttgttccaa caaaacctgt accgacgatt actactttac
    64681 gacttgtttt tttcatgaat aaacagctcc ttttcataac tatttgttac tttcatgaaa
    64741 agtatagtct tgtttattca ttttatcaac atgttaatta taatagttgt tattataatt
    64801 tttgatggaa acgaattcct gaatacgcat aacagataaa tgacaaatgt ttacacctat
    64861 atcccctgat aatacaacca aaagtttaga actgaaaata aatccaaaaa aattcgctgc
    64921 aacgatataa taagacagca atcgcaccta aaacaatttt ccttcatatg ctttagtgaa
    64981 agattttctt cttaatgttt atttctccat tcattgggag tacatgttga atacttcttg
    65041 aataatttga ataaagaagt cgtttgttta tatccgatac gattagcgat ttcttccaac
    65101 gaaaaactcg tttcttgaat cagttccaac gcaaagtcga attttttctt tagaaccagt
    65161 tcttgaaagg aagcatcaaa atacattttc aatttattac taagatagac cggattgtag
    65221 ccaaaatgag ctgctgtttc ttttaacgta caagaagtaa aatgcttatc gatataatct
    65281 aatactctaa gcatctcatt ttctgcgcat ccatctgctg atgaaaagct ttgttgttct
    65341 aataaatgag tcaattcgat cagtaatagt gatgtataga gatttaacga acggatctta
    65401 tgactgtatg tatcaaaata aatcaacagc atattttcaa tcaaatgcgt caaacgactt
    65461 gtttttccgc cgcgaaaatg aatgaattgt gtatgttccc ctttttcttt tgatgcattt
    65521 atcaaaaaag aagaaagtag attatttgtg cttgccaaat gattcaatat ctctgtagat
    65581 aaggtttctt cttttaataa gatgttgatt aaaatatcct cttgccctgt gtattcgatt
    65641 ctttgagtag cttctttatc aatgatcacc acgtcacttt cttccatctc tatcctttct
    65701 ccattaataa tttgtaaaca tgtaccgcta tacatataat tgatttcaac aaaatcatgt
    65761 gtatgctcgg gaacttccgc atatcgacgg tgtttactga tatgaatatt tccctgttga
    65821 aatagatccc ctcggtggat ttttggcggt gtctgaagat ggtaagctaa gtttaaatca
    65881 ttgatattca ttccttgttc acgctgcaga gtttcgattg attcttcgtt acgcaaaaaa
    65941 aatgtctaat tcagctagtt ccaattgact ccctcctttt tgtaagcggt ttctttcgct
    66001 tattagttca cgctgtactg ctattatatg caaagctatt tttggtttca taaagacttt
    66061 ctatggttgg gacatgaact tcctgtgatt ccgctattga gagaataacc acttcatact
    66121 atatttttga taagcgctta caaaaatgaa aggaacatgc ttatgaataa aaagatgatg
    66181 aaattttctc tgctgtcagt ctctcttatt ttgacttctg ctggtgcagt cacgtctgca
    66241 attcccagta tgtcagctac ttatgccacg cgttctttat ctgctgttga attattaacg
    66301 actgctccct cttttatggt cactattttt gttttgatta gtagttttat tgctaggaaa
    66361 atcggacaaa aacaaactgt gatcatcgga ttagtgattg catcgatttg tggtatc
//
LOCUS       DAFBSV010000005        56894 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.005, whole genome shotgun sequence.
ACCESSION   DAFBSV010000005 DAFBSV010000000
VERSION     DAFBSV010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56894
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.005"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(23..391)
                     /locus_tag="LLB18_000355"
     CDS             complement(23..391)
                     /locus_tag="LLB18_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HBK5243386.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            complement(1002..2393)
                     /locus_tag="LLB18_000356"
     CDS             complement(1002..2393)
                     /locus_tag="LLB18_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HBK5243387.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            complement(2606..2992)
                     /locus_tag="LLB18_000357"
     CDS             complement(2606..2992)
                     /locus_tag="LLB18_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HBK5243388.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            complement(3048..3671)
                     /locus_tag="LLB18_000358"
     CDS             complement(3048..3671)
                     /locus_tag="LLB18_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBK5243389.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNKLFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            complement(3735..4403)
                     /locus_tag="LLB18_000359"
     CDS             complement(3735..4403)
                     /locus_tag="LLB18_000359"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBK5243390.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            complement(4415..4855)
                     /locus_tag="LLB18_000360"
     CDS             complement(4415..4855)
                     /locus_tag="LLB18_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243391.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            complement(4914..5585)
                     /locus_tag="LLB18_000361"
     CDS             complement(4914..5585)
                     /locus_tag="LLB18_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBK5243392.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            complement(5770..6168)
                     /locus_tag="LLB18_000362"
     CDS             complement(5770..6168)
                     /locus_tag="LLB18_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HBK5243393.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(6165..6938)
                     /locus_tag="LLB18_000363"
     CDS             complement(6165..6938)
                     /locus_tag="LLB18_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBK5243394.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(6935..7618)
                     /locus_tag="LLB18_000364"
     CDS             complement(6935..7618)
                     /locus_tag="LLB18_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBK5243395.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(7785..8672)
                     /locus_tag="LLB18_000365"
     CDS             complement(7785..8672)
                     /locus_tag="LLB18_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBK5243396.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(8669..9538)
                     /locus_tag="LLB18_000366"
     CDS             complement(8669..9538)
                     /locus_tag="LLB18_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK5243397.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(9675..10961)
                     /locus_tag="LLB18_000367"
     CDS             complement(9675..10961)
                     /locus_tag="LLB18_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK5243398.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            11234..11812
                     /locus_tag="LLB18_000368"
     CDS             11234..11812
                     /locus_tag="LLB18_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBK5243399.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            11812..12741
                     /locus_tag="LLB18_000369"
     CDS             11812..12741
                     /locus_tag="LLB18_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5243400.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            12738..14372
                     /locus_tag="LLB18_000370"
     CDS             12738..14372
                     /locus_tag="LLB18_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBK5243401.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSINQLLSNAQHHYEQTIQD
                     EKKKRSLEIQTMQAQIQPHFIYNTLTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKK
                     EEVIPVKEEIKSVQSYIDLLSMRYGERISAKIMIPDELQSLSMPNMILQPIIENAYLH
                     AFHNKTQGFITVYGKTKNQLLLFEVIDNGDGFDTENTKQKNDHFSGIGISHVDERIRL
                     MYGDAYGLTIQSVIGTGTTVTICLPLLPKNQSEYQK"
     gene            complement(14435..15271)
                     /gene="pheA"
                     /locus_tag="LLB18_000371"
     CDS             complement(14435..15271)
                     /gene="pheA"
                     /locus_tag="LLB18_000371"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBK5243402.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(15268..15777)
                     /locus_tag="LLB18_000372"
     CDS             complement(15268..15777)
                     /locus_tag="LLB18_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBK5243403.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(15770..17065)
                     /gene="aroA"
                     /locus_tag="LLB18_000373"
     CDS             complement(15770..17065)
                     /gene="aroA"
                     /locus_tag="LLB18_000373"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBK5243404.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(17078..18169)
                     /locus_tag="LLB18_000374"
     CDS             complement(17078..18169)
                     /locus_tag="LLB18_000374"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBK5243405.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(18186..19352)
                     /gene="aroC"
                     /locus_tag="LLB18_000375"
     CDS             complement(18186..19352)
                     /gene="aroC"
                     /locus_tag="LLB18_000375"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBK5243406.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(19354..20418)
                     /gene="aroB"
                     /locus_tag="LLB18_000376"
     CDS             complement(19354..20418)
                     /gene="aroB"
                     /locus_tag="LLB18_000376"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBK5243407.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(20451..21473)
                     /gene="aroF"
                     /locus_tag="LLB18_000377"
     CDS             complement(20451..21473)
                     /gene="aroF"
                     /locus_tag="LLB18_000377"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBK5243408.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(22132..23106)
                     /locus_tag="LLB18_000378"
     CDS             complement(22132..23106)
                     /locus_tag="LLB18_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HBK5243409.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(23087..24970)
                     /locus_tag="LLB18_000379"
     CDS             complement(23087..24970)
                     /locus_tag="LLB18_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HBK5243410.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(24988..27213)
                     /locus_tag="LLB18_000380"
     CDS             complement(24988..27213)
                     /locus_tag="LLB18_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBK5243411.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEEKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            27328..28362
                     /locus_tag="LLB18_000381"
     CDS             27328..28362
                     /locus_tag="LLB18_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5243412.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(28429..29442)
                     /locus_tag="LLB18_000382"
     CDS             complement(28429..29442)
                     /locus_tag="LLB18_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK5243413.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(29520..29708)
                     /locus_tag="LLB18_000383"
     CDS             complement(29520..29708)
                     /locus_tag="LLB18_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HBK5243414.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(30148..30276)
                     /locus_tag="LLB18_000384"
     CDS             complement(30148..30276)
                     /locus_tag="LLB18_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBK5243415.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(30279..31652)
                     /gene="rlmD"
                     /locus_tag="LLB18_000385"
     CDS             complement(30279..31652)
                     /gene="rlmD"
                     /locus_tag="LLB18_000385"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBK5243416.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(31763..32818)
                     /locus_tag="LLB18_000386"
     CDS             complement(31763..32818)
                     /locus_tag="LLB18_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBK5243417.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(32828..34258)
                     /gene="gatB"
                     /locus_tag="LLB18_000387"
     CDS             complement(32828..34258)
                     /gene="gatB"
                     /locus_tag="LLB18_000387"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HBK5243418.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(34255..35727)
                     /gene="gatA"
                     /locus_tag="LLB18_000388"
     CDS             complement(34255..35727)
                     /gene="gatA"
                     /locus_tag="LLB18_000388"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HBK5243419.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(35727..36032)
                     /gene="gatC"
                     /locus_tag="LLB18_000389"
     CDS             complement(35727..36032)
                     /gene="gatC"
                     /locus_tag="LLB18_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HBK5243420.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(36138..38174)
                     /gene="ligA"
                     /locus_tag="LLB18_000390"
     CDS             complement(36138..38174)
                     /gene="ligA"
                     /locus_tag="LLB18_000390"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBK5243421.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(38191..40425)
                     /gene="pcrA"
                     /locus_tag="LLB18_000391"
     CDS             complement(38191..40425)
                     /gene="pcrA"
                     /locus_tag="LLB18_000391"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HBK5243422.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            40580..42139
                     /locus_tag="LLB18_000392"
     CDS             40580..42139
                     /locus_tag="LLB18_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HBK5243423.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(42250..44181)
                     /locus_tag="LLB18_000393"
     CDS             complement(42250..44181)
                     /locus_tag="LLB18_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK5243424.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(44199..45113)
                     /gene="pfkB"
                     /locus_tag="LLB18_000394"
     CDS             complement(44199..45113)
                     /gene="pfkB"
                     /locus_tag="LLB18_000394"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBK5243425.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(45110..45862)
                     /locus_tag="LLB18_000395"
     CDS             complement(45110..45862)
                     /locus_tag="LLB18_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBK5243426.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(46022..46231)
                     /locus_tag="LLB18_000396"
     CDS             complement(46022..46231)
                     /locus_tag="LLB18_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243427.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(46242..47570)
                     /locus_tag="LLB18_000397"
     CDS             complement(46242..47570)
                     /locus_tag="LLB18_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243428.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            47706..47861
                     /locus_tag="LLB18_000398"
     CDS             47706..47861
                     /locus_tag="LLB18_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243429.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(47935..48522)
                     /locus_tag="LLB18_000399"
     CDS             complement(47935..48522)
                     /locus_tag="LLB18_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBK5243430.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(48605..49855)
                     /gene="clpX"
                     /locus_tag="LLB18_000400"
     CDS             complement(48605..49855)
                     /gene="clpX"
                     /locus_tag="LLB18_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBK5243431.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(50102..51391)
                     /locus_tag="LLB18_000401"
     CDS             complement(50102..51391)
                     /locus_tag="LLB18_000401"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBK5243432.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(51545..52477)
                     /locus_tag="LLB18_000402"
     CDS             complement(51545..52477)
                     /locus_tag="LLB18_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243433.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(52634..53293)
                     /locus_tag="LLB18_000403"
     CDS             complement(52634..53293)
                     /locus_tag="LLB18_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBK5243434.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(53296..54321)
                     /gene="sppA"
                     /locus_tag="LLB18_000404"
     CDS             complement(53296..54321)
                     /gene="sppA"
                     /locus_tag="LLB18_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HBK5243435.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEKGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(54334..54624)
                     /locus_tag="LLB18_000405"
     CDS             complement(54334..54624)
                     /locus_tag="LLB18_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243436.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            55033..56838
                     /gene="glmS"
                     /locus_tag="LLB18_000406"
     CDS             55033..56838
                     /gene="glmS"
                     /locus_tag="LLB18_000406"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBK5243437.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINCLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
BASE COUNT        15913 a        12246 c        10087 g        18648 t
ORIGIN      
        1 aaaaacaaag tctttatttc tattatttac ctgtaaccgc aaagtagttg ccatcgggat
       61 cagcaaagtt aaagacatat tcttctccaa gctgtaccat atcacctaat gtgactgatt
      121 gcgtctgcat ttttttatat agtccaaaga tatctttact gtaaaacatc aaagatgggg
      181 cactagtagc tgtgccaggt gaatgggact caacaaatgc tcgatcatat aacagaaatg
      241 aggtttgact gtcctcaact cctacttcaa ttataagcgt cccatccatt tcttgacgat
      301 ctttttccgc aaagccaact gctctccaaa acgttgcatt tttttctaca tcgtccacat
      361 aaagcatgat ttttatttca ttcgtaaaca tctgtttcct cctaaacgat ctgttctaac
      421 attctcaact ttgtcagttt accataggaa aatgggaaaa tctacgaaag ctctcaacag
      481 aatcgtccta cttaaatacg cttttcttta ataataaata agttggttgt ttttgttatt
      541 tgcgctttca cttttcggaa taaataatgt gtatttatat ggaataaata aaaaaagagg
      601 tcgtgactaa aaacaagtca caacctctgg taaacggtgt tctcctgaca actcctcggt
      661 cacaagacac aatattcaac aaacatgaga agctattttt tgaaattgct ctttgtgact
      721 cagagtgaaa cggcaggctc acgacctctt tcttaaacgg tgttcaaaag cttgcatctg
      781 cggtaataag ctcaaccaaa cgtaaaatat gaggaactat ttttgtttgg ctgttcttat
      841 tacttgatgc agggcagctt tttcacaacc tcttattcac ggtgtttcag aagtagcttc
      901 tcggaaataa gccgaaattt cacaaaaatt tgagaaacta tttttaggaa acttcttctt
      961 atttcttaaa gctgaccact tctatcacaa cctctttttg actatgcatt cacatcgatc
     1021 actttagaat catcattgat gacatcgcga tctaaatctt tgatgcgtgc acttgtcacg
     1081 ataccagcta ccatgctacc gctgacgttt actgctgtac gtgccatatc gattaatggt
     1141 tcaacagaga taactaaccc aacgattgct actggcaagt tcattgcccc taaaacgatc
     1201 agtgaagcaa atgttgcgcc cccaccgact ccagctacac caaaagaact gattgttaca
     1261 attgccacaa gcatcaaaat aaattccaaa ctaaagacat tcactccagc tgctggtgcg
     1321 acgatcgttg ccaacatagc tggataaacg ccagcacagc cgttttgtcc aatagacaaa
     1381 ccaaaacttg ctgagaaatt agctgttgca tcatctactc ctaaagcttt tgtctgagtc
     1441 tcgatattca atggcaaagc tccagcactt gaacgtgaag taaacgcaaa gctcaatacc
     1501 ggaaaggctt ttttgaaata gttgattgga ttgacttttg caccaatcaa aatcagtgag
     1561 tggacaatca aaacagcaag caatgctacg taagaagcaa cgacaaattt acctaaattg
     1621 acgatagctg caaaatcact tgttgccaaa acgtttgtca tcaaagcaaa tactccataa
     1681 ggtgtcaaac gcaaaacaag cgtcacgatc cgcataatga ttttatacag actgtcgact
     1741 aaatctgaaa agaatgctgc ttcttttggc gcttttcttt tcacgcctag ataagcgatt
     1801 ccgacaaatg ccgcgaaaat aacgactcca atcgtacttg ttgcacgact acctgctaaa
     1861 tcagcaaaaa cgtttttagg gataaaggat aaaatctgct gtggaatcga taagttttca
     1921 actgtttcct gacgtgttgc cagttcagag attcgtgctg tttctgcagc tccttgtgtg
     1981 aatttagctc cttggagtcc gaacagcatt gttgaaccaa ttccgatcaa tgctgcaata
     2041 gctgttgttc caagtaaaga agtcaataca gtcgcactaa ttttccctag cttttcagaa
     2101 actttcattt ttgtgaatgc accaatgatc gatataaaca ctaaaggcat aactagcatt
     2161 tgcaagaatg atacatatcc ttgacctaca atcccgatcc attccattga ttgagtaacg
     2221 actttgtcgt ctacaccaaa gatcaattga agcagaccgc caaagacgat accaactcct
     2281 aatgctgtaa agacgcgtgt tgaaaatttt gtatggcgct tttgcatacg atagaacaca
     2341 tataataatg ccgcaaaaac tagaaccact aaaactgtga tgagtgttgt catttttctc
     2401 ctcctcatat tattaatgac aagtccatcg aaggaagtaa aggttcccga gaatgattct
     2461 tcaaccatcc tcctgaaaaa atttttttca gtgactttta tattttagac gatttttatc
     2521 gaaatgacat tctttttgct tacaattagt aataaaaaaa catacctgtg atagctttaa
     2581 tctatcgcag gtatgttttt actgtctatt cttgtttttc tgattgaaaa ttcaatttta
     2641 ccccaggctg atctaaggcg atctctgtca cctcataaga cattcggcgt acgatatcga
     2701 ataacggtgc tactagctcg tccacttctt cttgtgtgac atcattttga ccttcaattt
     2761 tccgattgag gatatgattg atctgactca cacttccaga taaaacatat gtatcaaaca
     2821 ctaaacggaa ctctaagcgt gctcctacga tgctatgttc tttcggatag ttttcgatcg
     2881 tttcttttaa aggcgagaag cctactttca aatctgtttc tacttcttgg ttcggcaatc
     2941 tcatatcata atgaaatgct tctacaactt ctttttgtct tctgatttcc atataatttt
     3001 atcactcctt tatgaaaatt ataacatatc tcctttgaaa ggggatacta ctttttaatg
     3061 atgctctgca aggtaaggat ttcattcaga tttcctacca cataatctgc cgggatctca
     3121 cccagaaaat gatcgatgtc gtaaagacaa gtagcgactc ctgcattttt ccctgcttcg
     3181 atatctaaac gacgatcgcc gatcatcatc gtgtctgttc tttctaaatg aaaagtatcg
     3241 atcaaataat ttaaagatgc tggatcaggt ttacgaggaa agtcctgatc gatccctact
     3301 acttcctcaa tcagatgtgc caatcgatgt tcttttaaca ggccccatgt tgattctgtc
     3361 aaacggtggg tcaggatgaa atgacgaccg ccgttgtctt ttagcatttc cagtacttgt
     3421 ttcgtttctg gaaatggacg ggaaacttcc gtactttctt tttcatatcg gtgaaataat
     3481 ttattaaact ctctggcatt caagtttgat tcattgatca aataactagt agaatacttt
     3541 ttcattttga agtagatttc ttttttgtcc atactgatac caaaatcttt tagtgcttgc
     3601 catgcaccat ctaccattgc gggatacgta tcaaacaatg taccatcaaa gtcccatata
     3661 taatttttca tgttcctttt gttccattcc tttgcttctt ttttctatct ctcactttta
     3721 gataaaggtg ttctttaaag tatttttttg tccagaattg tcaaatcatc tgctaatgta
     3781 tactggattg gttgtgcatt tgggatatcg atcgtatcca tttgatcttc aggaacatct
     3841 tctaaatatt ttgtcagtgc tcggatgcta ttaccatgac ccacaactag taaatcttgc
     3901 cgatctttta gttttggtgc tagatgatct tgccataagg gaatgatccg attcactgtc
     3961 atttccagac tttctccgta tgggatcaaa tgcggatcca agtgatcata tctgcggtca
     4021 aatctatttt ctgcggttaa cggcggaact tccgtatatc ctctgcgcca tgtttttact
     4081 tgatcttttc cgtatatttc tttcatctta tctttgtttt tacccacaag atccccataa
     4141 tgccgttcat ttagacgcca tgtttttatt ataggaagcc ataactgacc catttcttct
     4201 agtgcgactt gtccggtaag aatcgcacgt ttcaaaacag aggtataaac ggcatcgaat
     4261 tgaagtccgg cttcaagcat tttttgaccg gcaactgctg cttgttcttt tcctttttct
     4321 gttaaggcga catctagcca tcctgtccag taattttcaa aatttgcttc gctttcgcca
     4381 tgacgtaata atactaattt cattcttttc tcccttaaac attcgtttcg aattttatac
     4441 cacatgtttt gcatgtcaca cgtattcgtc cttttccttt aggtgcacgc tgcttttgat
     4501 gacaattcgg gcactcaaaa aaagtataac tttttcgatc cattttgact tgctttttgt
     4561 tttttatctg atgatatttt tctttgactc tatcaagata tttcaaataa cgttgattct
     4621 catttagtct ggggtagatt ttttttgata ggaaacgaaa tatcatccat ccgaaaaaga
     4681 cgatgaacaa caattgtccg attctatagg gcaaccaacg acttagcaaa ctaaagacaa
     4741 gcgcagcgat caatagaccg cgattcaact gatcaaattt cgcatatctt ccctgcataa
     4801 gtttgtgata gttctgctga aatcgtatta gcctttctaa ccatgtttgc atcatattat
     4861 ctcctccatc atctaatatt tattatgaca aaaaaatcca aaaagaaaaa gccttaattg
     4921 gccttttcca ttgcaacttg gtgaaggaca ttccgatttc tggtaaagtc aatcacaatc
     4981 actttctttt tatcttctct gttgactact cgaaatgtgt ccgtcaatgg aagaaacagc
     5041 ttcttagatg gtagctgttg catacgtata aaacgatgga tcatcgtaat caattgagga
     5101 aattgaatag acgtgtgaag cagacctgga tattttttca acagctgtgt cgttttgatc
     5161 agattccgtt ttttactgat cacttttaaa aagcttttta gaatcttttg ctgacgtcta
     5221 aaaatagaaa aagaattttc gtcatctatt tgataacgca tttgtttttg cagttctgct
     5281 gcagtcagat ggatcttccc atcgtttgta tcgatcatta aaccttctgg aaacagttca
     5341 accactgctc gatcccaaga ttcaagagaa agctcgatat aatcttttac tggtaattcc
     5401 aattctacct taaaaaagtg caaaacagcc gacagccctt ctgcttgata gatttctcct
     5461 aatgttagcc cctctagatg gaactctggt gaaaaatgca gcaatgtttt attttcctgc
     5521 aattgaacat atagaaatgt agatcgctca atcagagtat cttttaaaac aactaaaaaa
     5581 ttcatttttc tccccctttt ttcatcattt ttaaaatagc atattttgaa aagaaagtct
     5641 gatgcttaga gtagaatttc ataaaaattt actatttcat aagtattcac gagaaaaata
     5701 caaacaaaaa agcggaaata acgctcatcc gccttcttgt ttgtgtttat ttcctcttca
     5761 aacgcttgtc tatgattcag acttttctct atcgttattt tcatctaaaa gttcttgcat
     5821 tccgataatt tctcgatatt gatgaatctt agtgatacca atgactttgt ctacatcaat
     5881 actaaaacaa ataccattac ctggaatatc gatgttgatg ccttgaccaa tcgcatccat
     5941 tactttattc gtcaaactat cgggtactaa tgtcaacaca atatcttttt ctggcgaaat
     6001 gtccaaacct aaaaatttcc ctgaatcatg tacaccagaa cctcttccat gtaagatcgt
     6061 tccgcctgct gcacctgctt cttttgaaaa gtcgataaca tcttcgccca ttcctccgtc
     6121 aacgatcgtc acaatcatgt gaagattcaa tgctacaaga tctttcattt gctttccccc
     6181 aatttttgca atctttcttt ttcgattctg tctttttcat cttttcgttt ataaatatat
     6241 cctagtacta aagtggataa tattggtgtc aatgcaatca ttgcaaccac accaaacccg
     6301 tcaatgatcg gatctcttcc ttcaatttgt gcagcgattg ccacgctcat tgataaaata
     6361 aatgtcgaac acatcgggcc cgttgctact ccaccgttat caaaagccat tgctaaaaag
     6421 atcttgtcca cttttcgtcc taaaataaat gctagcccgt atcctgggat caagaaataa
     6481 taaagagaga atccgacgag caaacgccac atagacaatc ctactgctgc gccgatccca
     6541 attgaaatta ccatcagcat gattttcgat cggattctcc cctcgctcaa ttcttcaacc
     6601 tgtttgatca ttacatgaat cgccggctca gcaaacccta ctaagaaccc cattaaaaag
     6661 ccaaggggaa ccagtatata attgtaaggc aatcccgcaa tagcactgcc taaatgctgt
     6721 cctaccggta cataagccat attgactccg tgcaggaaaa ggatcaaccc aatagtcgtt
     6781 atcaagaaac ctttcataat gtcaaagaaa cgctttttgc gcatacgaaa actaatgata
     6841 ttcattaaaa caaataggat tacgataggt gccactgcca aaatgacttc catggtaacg
     6901 atttcgattc catctatcac ttgctgccag aaactcattg gaagatcacc cccaaaatca
     6961 tcacggcaag aatcggccct aacgaagcaa taccgaccat tccaaaactg tcattttcat
     7021 ttttcttttg tttgatcata ctagtcatcc ctccggcaag ggccaagata aatggaacag
     7081 ttactggacc agtagtcact ccccccgaat caaaagcaat cggcataaat tcggaactgg
     7141 tgaaaaatga ggcgatcaaa acgcctatgt agcctatagc catcaattga taataggata
     7201 gcttgaatac gacccgaagc agcgcaaagg ctagaaatac tccagtgccg acgctgacga
     7261 tcccaatcag caacactctg ccaatctctc cgtcagatat atcatatact tgttgtccca
     7321 aaacttgcac ggaaggttca gcaatcgtga tcacgatccc gatagcaaat cccaaactga
     7381 ccaaaacggt caaacttttc tttttgatca tatatttccc tactagatct ccgacttcca
     7441 tcatagaata atctgctcca aacaaaaaga gcgtcattcc gatcatcatg attgccgcac
     7501 caaccagaaa tgaagcgagg tcttctcctt ctaacggtgc aaaaacaaac gttaaaatga
     7561 caatcaggac agtcatcggc aatatagcag caatcacttc tttaaaattt tttagcatgt
     7621 atcctcctcc tttactcttt aagtttacct taaaatgaaa gagttttcga gcacaaactt
     7681 aaaacgttat catttaattt ttctcaacat aaaataacac acgtcccaaa agtatctttt
     7741 tacttggaaa aatgactttg aaggaacgcg cttattgtgt ttttttattt tacagagccg
     7801 atcattcctt gaacgaattg cttttgcaaa acaaaaaata cgatggcagt tggtaaagta
     7861 gcgatgacta atccagccat gatcattcca tagtctggtg tataggaagc acccatagca
     7921 gataaaacaa gcggaaccgt ccgtttatca ggagattgca aagctactaa gggccataaa
     7981 taattgttcc agctactcat gaatgtgatg attgcagccg cggcataggt atttttagcc
     8041 gtcggcatat acactctaaa aaaaatactt agttctttta gaccgtctaa tcgagcggct
     8101 tctactagat cttttggaaa agatttaaca ttttgtcgaa agaagaagat caaaaaagca
     8161 gtgctaacag atggcaggat gacaaccaag aaactgttga ttcccaaaac cgttccgttc
     8221 aattgtgaaa acattcgata taaagggatc atcaatgccg caaaaggaac catcatcgat
     8281 agcagtagaa tattgaaaat taggtctttt cgtttacttt gataaatctc aaatccatat
     8341 cctgccattg acgaaatcag caatgcaaac acagtggtca ccaaagcgat catcgctgaa
     8401 ttccaaaggg aacgagtaaa attcagctca ttggaaaaca aattttgaaa attgatgatc
     8461 aagttactgc caatctttat ttttcccgat gtgatatcca cgggtgtatt cgtcattccc
     8521 aaaaccatcc agacaaaagg gaaaatggaa ataaatgata ggatgcttaa tgctgtatac
     8581 tttaatactg acccaattgt cgaacgaagt tctaatgctt gttttttgac gttggggcgt
     8641 tcgattgttt ctttttctac catatttttc atcgactttc tcctcctact ttcgtttgga
     8701 ttatcgacaa tatcacaata aaggaaacaa taacaaagga aactgctgcc gcatatccaa
     8761 aattaggcgt gaatttataa ctcaaattat agatgtattg agatagggtg gtcgttgcat
     8821 ttgctggtcc cccgccagta atattttgta cttcatcaaa aagctgcaat gtcccgatcg
     8881 tcgaagtaat ggaagtaaac aaaatgattg gttttaaatt tgggatcgtc actttgataa
     8941 actgctgcca tttagaagca ccgtcaatag atgctgcttc ataaatctcc gaatcaatat
     9001 tttgcatgcc tgaaaggaaa aaaatcatat tgtatccagt ccaacgccaa gtgatcgaaa
     9061 gaatgatcag aactctcgcc caaattggat gagtcaacca gccaatcggt gtgtcaatca
     9121 taccaatgcc caacaacaag ttgtttacaa ggccagattg agaaaataga cttttcatga
     9181 tcagagaata actgaccatc gaagtgatac atggaagaaa gatagcggtt cgaaacaacc
     9241 ctttatattt caacttttta tcatttaaaa ggttggaaat aaaaagtgct agaaacaaca
     9301 tgatcggtac ttgtacaagt aaatacagga atgtattaaa aaaagctttt ttaaaagttg
     9361 catctgtcaa catccgctga taattaccta acccgttaaa tgtcatattg acagggggac
     9421 cactttgaaa agacgtgatc aaagccaaaa ccatcggaat aaaaaccatg attgatatca
     9481 aaatgactgg caagattaaa aaagcatgcc cgtttttgaa taaatctttc tgcttcattc
     9541 ttttccctcc aattctatca ttgattatct acatgaaaag acaagaaaga caatatctgt
     9601 aaggcagacg tgatcttttt tgtcttttcg tttgtctgat gaaaaagcga agaaattcac
     9661 ttttttacca ccgatcaatt agccaattgt gcttctactt gtttttgtgt atctgctagt
     9721 accttgtctg tctcttctcc attgatgatt cgatgaagag cttcagctac gactgcttca
     9781 attgcatagg tctcatgtcc gtaattcact tctggtattt cagatgtcca tgttgaaaaa
     9841 tcgtcaaaga tcttttgacc actgtaaaat tcagaagctt cttgataagc ttcttgttca
     9901 ttcgcgctaa gcatcgtaga tactagtccg atttctttcg caagagtgcc catcagttct
     9961 tcattcgaag caaacgttgc ttctaggaaa tctttcgctg aatcttctcc agctactcct
    10021 ttgatcacat accagccagc gccgccaagg ttagaagctt gcgctttttg cagattttct
    10081 ggaagtgcag gtattggtgc aatcttccat tttccagatt ggttttctgc tccttggatc
    10141 gttgaagaat accaagcgcc agttgggcta gaagctactg ctcctgattg tatcgcagtt
    10201 actccagcat tccagtcaga ggtttgttcg actagatctt ctttcaaaag agtggcaaac
    10261 aattcaagac catactttaa agatgcattg tcttggatcg tgactgtctc cccatcttca
    10321 gatgtatacc attctcctgc ctgttgcata atcatcctta ctcgaccaag gtcagaagga
    10381 ttgacttcag cgattttctt tcccgtcttt tctttgacat ctcgcgctac ttgaatatac
    10441 tcgtcccact tcagattctc catatcctct tctgtataac ctgcttctgc catcagatcc
    10501 gtacgataga agtttgctgt tacgcccgaa tcgaaaggaa caccgtatat tttatctcct
    10561 actttgttta ccgcaaattt atacggtgca aaatgatctt cctttacaat agcagacaaa
    10621 ttagcgaatg catctggata agaagtcaaa tagccttgta tcctataatc ttcaatcaag
    10681 acgatattgg gcaatccttc tgtattcccg ctcgctaaag cggtgttcag tttctgaacg
    10741 atatcatcct gagacatcgt aacaacttct atctctgttt cttcgttctc ataaactttt
    10801 tttgcttcat tcactgcttt gatattgaat gtctcatccc acgcccagac agtgactttt
    10861 tcttctttgt ctgctgtact actagcactt ccgcatcctg ttaagaaacc tgatgctgcc
    10921 gctaaacaaa cgactccagc aattaacttt ctgatgttca tttttatccg ctccttttcc
    10981 atccattagt tgtttacgtt tgctacattc atcataccaa aatttgaaaa cggtttcttt
    11041 attattcaga tacttcaaaa atttctccta aaataataaa aaaatacaaa tcaactatga
    11101 caaaaggaat aatcttagca tctagaccaa agatcgaaat ggtgaggttt ctttaaaata
    11161 aaaatatcct tgcattttct cctagaaata agtattttta aattacaaga ctattcttaa
    11221 ggcgggtaaa aaaatgccaa tacgcgtaat tcttatcgat gatgaacaga cgattttaga
    11281 tggaatgaaa cagttgatca attggtctga gcacgggttt caattaatag ggactttttc
    11341 cagtccgctg aaagcgcttg atttttcttt ggtacatgca atcgatatcg tggtcacaga
    11401 tgtaatgatg cctgaattaa atggaatcga attatcgcgg ctattaaaac agcaacaacc
    11461 tgaaacacag atccttatcc tctctagcta tgatgaattt gatatggtta aagattcttt
    11521 taaagaaggc gtcgctgatt atcttttaaa gcctcgattg agtcctgatt tttttctaaa
    11581 ttccttaact gccgtttcac aaaaaatcaa aaaaaagccc aacaaaagcc caatcaccaa
    11641 tcgttatgag cagatctgcg agaatctttc acagcagatt gctggacaaa ctcgtccatt
    11701 gcttgaccct cttctttttg aacacacctt gtttttctgt tatataccga aaaacggcca
    11761 ttcagttcaa aacaaggctc taaacaaaaa cagtcgatca cccattcatt gatggatagc
    11821 gacgattcgt ttactattta tcctgtttct accttttcgg aagaatccgg ctatgtaatc
    11881 aatactgatt ccaaagatac acttaggaag tttgttcaaa agtttcgtca agaagttttt
    11941 ccaggtgatt tttttgttgt ttctgattct tttgcaatcc aagatatcaa tgaaatattc
    12001 caagagatca gaaattgcac caaaggacaa cgtttctatc ataagggaaa gaaccttgct
    12061 tatcagcatg aacttcttcc gttattaacc aaccacgagc agcaagcaag tagttattta
    12121 acaaaaatcg ttcataaaga ctacgcttta gctgtcaaag aacttgagaa tttcttcacg
    12181 acgatattgg aacagcctat tgatccagct tatttgaaac atgaggcaat caatcgtttc
    12241 tatgcattac tcaacgcttt ggctgacgag catgttggga atgaagaact ttctttgctc
    12301 aagatcgccc ttccttcttt attagccgat gctgagtatt tcgaagattt ttctattctt
    12361 gtcaaagaaa cacttgagaa actcacccac ttttctgcaa atgcaaaaaa agacaatttc
    12421 gatatcttga ctttgatcta cgagttcgtc caggaaaatt atgagaaaga aatcaattta
    12481 caacttttat ccgaaaaata tcatttttca tatagctatc tctcagccat ctttactgaa
    12541 aaatttggta tcaacttttc aaaatatcta aaaaaagtcc gtatcagtaa agccaagctc
    12601 tttttgacgg aaacacggct tactttgacg gaaatctgtg agaaagtcgg ctataccgaa
    12661 ctgggttatt tctccagagt ttttaaagaa gagacaggaa tgacaccttc tcaataccgt
    12721 aaaggaactt ttgtaaaatg agaaaaaaaa tcaaagagca tgaactcttt gccaaacttc
    12781 tgttcatttt gttcatcggt ctttttctgc aagccatcgt catttctttg tttatttatc
    12841 atcgatcaag ggatgcctat atccagctgt tcaatcaatc gaatgatgtg gtactaaaaa
    12901 agattcaatc tgaatttgaa agtttgaatg atacaatcga gaatacatta gccgcttttg
    12961 attctaatcc agctgtcaaa agctattttt ccaatgatcc agcccaacat atggaacagc
    13021 ttcagcaact aagaacaatc caaaaaatga atgactctct ttcaaaaatc catccaatga
    13081 tcgattacga tgtattgatc tttggagaaa atggaagaac ttttgtcgga aacgacatgc
    13141 tcactgccgt atctgccgat tctttttttc aatctgcgat tgctcagaga gtgaatgaac
    13201 gtgctgctga tacacaaatg ctttttgcac accacggatt gactcttcgc gataagaaag
    13261 cacccagcgt cttctttgtc aaaaaactga aaaatacatt gaatcacgtt tacggatatg
    13321 ctgttttatc gatctcatcc aagcaactag cgaatctttt tcaatctgta gtaaatcctg
    13381 agatatcgaa gatctccttc atgaacgaag aacagacgat catcgcatca aatgaagaaa
    13441 atacaattgg gagccgatca atgattttca aaaaactaac agtaggtgaa acaacgattt
    13501 caaatggaca gcagttgacc cgtcttcctc tgtaccgcca ggattgtaca ttactcagtc
    13561 aagtcgatct tcattcttta tctaaccaaa tgggcgtgat ttttccgatt attttgtata
    13621 atatcgtgac acttgctttt gctggctcat tggtatttat gtatttggat cgacacacaa
    13681 aatcgatcaa tcaattgcta agtaatgctc agcatcatta tgaacagacg atccaagacg
    13741 aaaagaagaa acgttcgctt gaaatccaaa ctatgcaagc acagatacag ccccatttta
    13801 tttataatac gctgactagc ttgaaatttt tgatttggca gaaaaaaaca gatgaagcag
    13861 ttcaaggaat cgacagtttc attactttac taagaagtac gattgggaaa aaagaagaag
    13921 tgattccagt caaggaagaa atcaaaagcg tacaaagtta catcgatctt ttgagtatgc
    13981 gatatggcga aagaatctcg gctaaaataa tgattcctga tgaactgcag tcattatcta
    14041 tgccgaatat gatccttcaa ccaattatcg aaaacgccta tcttcatgct tttcacaata
    14101 aaacgcaagg attcatcacg gtgtacggca aaacaaaaaa tcagcttctt ttattcgaag
    14161 tgattgataa cggcgatggc ttcgatactg aaaataccaa acaaaaaaat gatcattttt
    14221 caggaatcgg catcagccat gtagatgagc ggatacgcct aatgtatggc gatgcatatg
    14281 gcttaacgat ccaatcagtg attgggacag gaacgactgt aacgatttgt ctaccgcttc
    14341 ttcctaaaaa tcaatcagaa tatcaaaaat aaagaatagc caagcgctga tttttttatt
    14401 ttaagttaaa taaatcaatc agtattcttg actttcatct acgcgtctct tctactgtca
    14461 gcactggata acagcccaat atttgacttt ctcctccgag catcttgatt tcttggagcg
    14521 cattctctac taatgtcatt ggacggtcca acaacaaatc gatcacgaaa aaatattctc
    14581 ccaagctagt tttcaatggt cgggattcaa tcttacttaa gttgatttcc cgccagccaa
    14641 aagctgccag cattttatga agcatccctg gccgattagc aggtagtgtc aagatgacac
    14701 tcatttttac tggagctgac tgctggctgg tcatctttcg gtcaccgacg atccaaaaac
    14761 gtgtctggtt caactcatta tcttggatat tctcagctaa gatctccaat ccaacatgct
    14821 gtgctgtttc taatgaagca atcgctgctg cgtcttcttt cggatgttct gctacataca
    14881 ttgctgcagc agttgttgat tctgttgcta ctaaaggaac attaggataa tgcgtttcta
    14941 aaaactgttg tgattgtgct agtgcttgtg gatgtgaaag gatttttgta atctttgttg
    15001 ctggattgcc taaaagctgc tgcttgatag gaagaacgat ttcactttta acttcgactt
    15061 ctggatgttt ggaaagaaga tcgattgtgt gatgaacagc tccttccaat gaattctcta
    15121 caggaacgac agccagatcg acttgtttgc gaaacaaagc gcgcaaacaa acagggatgg
    15181 aagcatacgc agtcaattgt tctgtaggaa atagctgaca agccgcctga taagtgaatg
    15241 aactttctgg ccctagatag ctgacgttca tatgcttttg atcctttcta taatggtatc
    15301 gatgatcttt tctggtgttt gattggtcgt gttgattcga tgtgtcgcac tttcttcata
    15361 ccaagaaagt cgttgtgcca ataatgcttt tatttcttct cttgtttttc caagagctaa
    15421 aggtcgaata gacgtttcat cttgttggat acgatcaact agacagtccg cttctgcctc
    15481 taagtaaaga acaatcggct gtgtttttaa aaaacgccga ttttctgcac tttggacaat
    15541 ccctccacca gtcgcgataa ttttgtcttc atttgacagc tttcttaaaa tatctgactc
    15601 cacttttcga aagctttttt caccgtaata gtgaaaatat tcggcaatcg acaattggat
    15661 atgttcctca atctttgtat ctaaatctac atactctttt tgtaaacatt gagctaaccc
    15721 tttaccgatt gttgtttttc cagcgcccat gaaaccaatc agcaaaatgc tagccatgag
    15781 cttctcctcc tgacacaagt tctgctaaat cgtcaaaaaa tgccggataa gagattgaaa
    15841 cagcttcagc tccttctagt tcgcaaggtc catcagctat caaagcagct acttgcagca
    15901 tcataccgat tcgatgatcg cctctgctgg acacttttgc gccatgcaga ggtgtcggcc
    15961 catggatgat cagaccgtct gctgtcgctt ttatctttgc tcccattttc tgtaattctt
    16021 ctgccaccgc atcaattctg ttggtttctt ttacttttaa ttcttctgcg tctttgatga
    16081 tcgtgattcc ttctgcttga gtagccacta aagctagaat gggcaattca tcaatcagac
    16141 gcggaatgat ttctccacca atcgttgctt tcttcaaatg actcgtcttg acacttaaat
    16201 cagccgattg gttctgttca ttgtgattcg tctgggtaat cgctgcgccc atctcctcca
    16261 acacatctaa gataccagtt cttgttggat tgaccccgac attttttaac aacagttggc
    16321 tttccggaac aagaagtcct gctgctagaa agaaagcagc tgatgaaata tcacctggaa
    16381 cagttatctg ttgaccagtt aatttttgcg gtccggtcac tatgatcgtt ttatcttcca
    16441 ctgtgatcct tccgccaaat tgacgaatca tttcttccgt atggttacgg gaacgttctt
    16501 tttcaacgat tacggatgtg ccttctgctt gtaatgccgc aaacagcaaa gcagatttga
    16561 cttgcgcact ggctacaggc atattgtatc ggataggtga taaagagcgg gttcctgtca
    16621 cagtgattgg tagatactgg tcattttctt ctccttgcaa gtcagcgccc atctcgcgta
    16681 aaggttccat cactcgcccc attggacgtt tagacaacga agcatccccg aacagagtag
    16741 tcgtaaaagg ctgtccagcc aaaataccca tcaataaacg tatggtcgta ccggagtttc
    16801 ccatgtcaat tgattcggtt ggttggacaa atgagtggct accgcgacca tgaatcttga
    16861 tcacctcttc ctcttcttcg atctcgacac ctaattgttg gaaggcatgt aaagtactca
    16921 gacaatcttc tgcgcgcaaa aaattttgta tagtcgtcgt tccttcagca attgctccaa
    16981 acatgatgct gcgatgggaa attgatttat ctgctggtat cctaacagtc cctcttaatc
    17041 catgtatttg ttgtaataat tgcatttatc cagcctccta tttgatccag caatgataac
    17101 tggtattaga cataatgatt ctttttgctt gtaacaaatc ctgttggttt ttaaaactga
    17161 tttgcagtat tcctaaaata tcttccctgg tctcttggat cttcaaatta atcaaagaaa
    17221 ctcccgcttt tccgatcagt ccagttactt ctgcaataac gccaggttca tctggcacat
    17281 cgataaataa atcaaaaaag gcaggaatcg cgccttgctt atggacaggc aactggtctc
    17341 gactttcttt tgcccgattg aaaaaagaaa agatttccga ttggttctca gtcatgatcc
    17401 attctgctat ttgtgtcatt tcttgttgcc aatctgccaa tcgttccaat aatatctgct
    17461 tattgctcaa caaaatatct gtccacatga caggatctga ggaagcgatc ctagtgatat
    17521 ctcgaaagcc tcctgctgcc agttgtttgg ctcgcggata ctcttgattg aattgttctg
    17581 cctgattgac taagccagct gccagaatat gtggaaaatg acttagcatt cctgttatac
    17641 ggtcatgttc tcttgctgta agagttacat attttgcttt ggttccgcaa aatagttctt
    17701 gcagtttttc aacatctttt ttcgtctttt ccaaaggtgt aaagatgtaa taggcatttt
    17761 caaatagttt agcatctgct gcctgtatac ctgatttatg agaaccagcc attggatgtc
    17821 caccgacaaa ccgaagattt ttctgctcag cggatgtcac gacttgctgc ttcgtactgc
    17881 tgacatccgt aatgatgacg tgatcagaca agttgattct ttcaaggaca tcaagataag
    17941 ctaaggttgt acggacggga acggctaata agataacgtc tgcttgttct gcacctgttt
    18001 caaaatcact tgcaacgtaa tcaacgatct gctgttctac tgcttgctca cgggtttttg
    18061 actgactatc ccaaccaact actatcagtt ctggattggt ctgacgaata caaagtgcca
    18121 tagaagcacc aatcagtcca agccccacga taaaaacatg ttgtgccatc ttatttgccc
    18181 cctttttagt aatgtttcaa gtagtcacgg tactccttca ctgcagcttt caactcaaca
    18241 agcgaatcac ttgggaattt tgacaatagc tctgtcgcta ccacagtggc tacaacattt
    18301 tccgcaacga cgctagctgc aggaactgct gtactatccg aacgttctac acttgctttg
    18361 taaggttctt ttgtatcgat atcaacactt tgaagtggct tgtacaatgt aggaatgggt
    18421 ttcatgaccc cgcgaatgac aagtggttcg ccattggtca ttccgccttc gaagccgcct
    18481 agattattgg tacgtcggaa atagcctctt tcttcttccc ataggatctc atccatcact
    18541 tctgagcctg gtaatgaacc agaagtgaat ccgaccccaa attctacgcc tttaaaggca
    18601 ttgatactaa ccacagcttg tgcgattttg gcatctagct tcgtgtccca ttgtacgtag
    18661 cttcctaatc cagctggaac gcctccaacg agcacttcta caattcctcc gatcgtatct
    18721 ccatttttct ttgtctgatc gatcaaatct tttattcttt gctcaactgc tggatcaaca
    18781 actcgtactt ctgacgcttc agaaatttct ttgatttctt gaatcgagat atttccaggt
    18841 atttctgctt ggattccacc aagacaaatc acgtgtcctg ctacgatgat gtcaagttct
    18901 tccagaattt tcttggcaat tgcgccgatt gctacacgca tggtcgtctc tcttgcagag
    18961 gaccgttcaa gcacattccg aagatctcga tgatggtatt tcataccgcc taccaaatcc
    19021 gcgtgtcctg gacgcggacg tgcaactcgc cgcagtgatt ggtctttttc aggcacttct
    19081 gctacagaca tgacagttgt ccaatttttc caatctttat tttctaccac taaagtgaca
    19141 ggtgaaccaa ttgttttgcc gtgacggatg ccagacgtga tccgaacacg atctttttcg
    19201 atcttcatcc ttcctcctct gccgtaacca gcttgtctgc gagcgagttc gtgattgatt
    19261 tcttcttctg acagaggtaa tcctgctggt agtccttcaa taatggctgt taattctggt
    19321 ccatgggatt ctcccgcagt catataacgc atcttacagt cctcctaagt aatctttgaa
    19381 tgtctctgtg ggaacaggaa cgatttttgc ttgcccaatc ttttctagca agatgatatt
    19441 caattggctt cctcttgctt tcttatcatg ggttatcgcg tggaataatt catctggatg
    19501 acttagatcg tacgtaatcg gcagatggaa tttttgaagt atcctttcta aagcagctgt
    19561 cgatccagtt ggagacaagc cgattttttc tgcatgagaa gtgatggcta ccattccaat
    19621 agctactcct tctccatgac tgactacccc atatcctgct gtattttcaa ttgcatggcc
    19681 aattgtatga ccaaaattta aaataagtcg atttccttgg tcaaagacat cttcttccac
    19741 tacttttcgt ttgatttcca acgtagcagt aatgattgga acagcatgtt ccagaagatc
    19801 tttttcgtct ttcagctcgt tcagctgttt ccaaagcgtt gcatctgcta tagctgctga
    19861 tttgatgatt tcagcgattc cttctcgtaa acgacgtacc ggcaaagttt ttagaacctc
    19921 aggatcaatc aatacaccag ctggctggct aaatgttccg acaaggtttt tcgctttgtt
    19981 tgtattgact gctgtcttcc cgccaatact agaatctact tgtgcaagta gcgtagtcgg
    20041 aatttgaacg aaatggatcc cacgcatgaa cgtcgaggcc acgaatgctg ctagatcacc
    20101 caccattcct ccaccaagtg caagtatccc atcgctgcgg gtaaaatcat tatctgctaa
    20161 aaaatcgtat aactcagctg cttgttctaa agatttactg gtctcacccg ccggtacgat
    20221 tgaaaggact ggttcaaaat tagcttgtct caattggaac atgatttttt ctgcatatag
    20281 tggagcaacg tttgtatcag tgatcacagc tactttttga ggtctccaaa tcgtttgaag
    20341 ccatgatcca gcctgttcta gtgcgccttt ttcaatatga atatcgtatt tttggttatc
    20401 aacatgtaca gtaagcattc gtttcacttc tttcttttaa aaagctggaa ttaatcgagt
    20461 gtctgaatct tttccattgc ttctttcatg atcgcaactt ctttcatcat gcgtgagtaa
    20521 gtcttttcat tcaacgattg gggaccgtct gaccaagcat ttgcaggatc aggatggatc
    20581 tctacgatca tgccatctgc tccgcttgcc acacccgcac gagccattgg tggtacaagt
    20641 tcccaaattc ctgtaccatg acttggatca acaatcacag ggaaatgagt taattttttc
    20701 atcaatggga cagcacttaa atcaaacgta ttacgtgtcg ctgtttcgta agtccgaatc
    20761 ccacgttcga taaaaatgac aggagatttg tcttcgactg caatgtattc tgcagcatta
    20821 agccattcat tgatcgtacc ggaaattcca cgtttcaatc caacaggttt acctgtttta
    20881 ccgacagcag atagcagttt aaaattttgc atattacgtg cgccaatctg taggatatcg
    20941 ctgtactcag ccaccatatc gatatgccct tcatccatca cttcagtaat cactttcatt
    21001 ccaaattcat cagccgcttg acggatgtat ttcaatcctt cttcttctaa accttggaaa
    21061 gcatatggag aagtacgtgg tttgaaggca ccacctcgca gaatttttgc gcccccggct
    21121 ttggccattc gcgcacattc tctgatttgg tctaatcctt cgatagaaca aggaccagcc
    21181 atcgtcacga aactgccgtc accaattttt actccgtcta catccacgac tgtattgcca
    21241 ggatggaatt ctcgagaagt caatttgtat gtgtttaaaa tacgcacagc attttctact
    21301 ccttcatagc gtgtaaatgc tccttcttgt aaacttcgcg tatcaccttt tagtccaatc
    21361 actactcgtt ctgttccttg atcgattgag actttgaatc cttctttttc gatatgatcg
    21421 acgacttttt ttatttgttc ttccgttgct tcttttttca taattactat cattgttttt
    21481 cccgctttct tttgtttact tatctatctt ggctgatttt ctctactttt tcaaggtggt
    21541 tttacattaa ttcctactaa atgaccgtgt cctgttgttc tcattttcgc tccttctttc
    21601 ctacttatga cccagataat caacaaaaaa agatgtccct gtaggaaatt gcctctacag
    21661 tgaacatctt caacgagcct taaaaagcgc tgcaaaaata taaaatagcc actatagatg
    21721 aatttctcta cgtggctgta agtcgtgttt aaaaatcttt agccatcata gatacaaacc
    21781 tggtttgttt gtacccacga agtcatgaat acaaacctat ctaaaatagc taaagtaata
    21841 cgtattcagt tttgtaagtt ttctagattt cataaaaaat cgctccaaac tgatgtaaga
    21901 attgtaccta gtatagacat aaaaaaatcg actgtcaatc atttttatga aacttttttt
    21961 aattttctga tagttaactt tgtttttcag aaaaataaca attggtttta ttgaagaaaa
    22021 tagtcatgaa caaaagtatc tgagaacttt tttactctct tgttcatgac atatagaata
    22081 aagcagcttt gtcttgtaaa ctccgttttt caaataataa tctaaagatt gctactgaat
    22141 aataaagccg atttcatggt cctcttcgct gctgattcgg taaggtgact caacatccgc
    22201 tccccagcta ttgatacccc cgactcctct tacttttgca aaaatcgtaa gaaccgttcg
    22261 tctttctggc ggtagttctt ctatatgtgt tgcctgttcc agttcttctg ctttgaatgg
    22321 taaagcggaa aaagcaaatg gcgtatcctg ctgttcaaat cgcaacgaaa aatcttcttg
    22381 atctttatcc gtattatcca acgtttgatt tcttgttagt tctacccatt tcgtttccat
    22441 atgcatgccg cattcttggg gaacaaggta tggggaaacg gggagtcctg ccactttata
    22501 aataccttcg acaccaccag ccatccgatc cggatatgtt tcccctgata ggccttcata
    22561 ctcaaaaaat tttgctttcg ttggcataat gaaccttaaa cccaatgcgg gtaattccgg
    22621 taatcctttt tgtccataat aatgcatatt gacaagcatt ttaccctctc cagcgatttg
    22681 gtaggaaatt gtcacttggg tttttggtac tgtgttgatt tccagtgtaa aaatgatttc
    22741 aaccgtttca gcgtattcat tacttgaata ttgattattt actggagcaa tcggcaaatc
    22801 gatcttttta ttgtccacca gtacttctat ttctttgact tttggataca atccggctcc
    22861 taaccacata ccggatttaa atccaaatcc gctacctctg tcattatcgg tcgttgctcg
    22921 ccaaaaaact ggaagtgttt cccggtatag ccattctttt ccgtttttat tgagcgattc
    22981 cagtccgcct cttgtataag aaaaaatata atgcgtattc cccgatttga cacctaatgt
    23041 acagtcgccg aagacgattg caactttttc cgtatccata tgacttttat ttactgtatt
    23101 tttcataata atatcttacc tcctgcatgg cgggtttttc ttgtccatct gcaaaaacga
    23161 tcccattccc tgagaattca tagtcacttg gtttatcgtc aaagtcaccg ccatagcgca
    23221 tcacttctct gcctgtgatt ggatcagtca cttggatcgc ctgatcttta aaatcccata
    23281 tatagcctcc ttggtacatt tcataacgat caagcaacgt catgtaagaa tccattccac
    23341 ctaacgaatt ccccatgtca tgcatatatt cacataagat gaacggtttt tccgctttat
    23401 tttcaaggta gtcaatgatc tcttctggtg gcgcatacat gcagcttttt acatctgaaa
    23461 tcgaatcttc gaatgctgga tttggaaaat tcccttcata atggacaagt cgatcggggt
    23521 ctactttttt gaagtaatcg ttcatttgtc gaatgttttc ttccgcataa gattcatttc
    23581 caagagacca aaaaagaata cttggatggt tttttaatgt ttcgaaattc gtttttgctc
    23641 gatcaagaac agccgcctgc cactgaggta ctgcacctgg tacgttgtaa gaaggctcaa
    23701 atgcgcccat tttttgccat gagccatggg attcgaggtt cgtttccgcc atcacatgga
    23761 ttcctgcttg gtcgcataaa taataccaag tgatctggtt ggggtaatga gatgtccgta
    23821 cgccgttgat ctttgcattt tttatgatag ccaaatcttt ttccatatct tctatagtga
    23881 tggcgcgtcc ttttttcgga tgccactcat gtcgatttac cccgttgata atcatccgtt
    23941 ttccattgaa gtagatgatt ttatctttga tttcgatttt acgaaaaccg aaggaatagt
    24001 caatatactc cgttactctt ttttcttcgt ctatcgtctc caattcaagc ttatataaat
    24061 tgggctgaaa atgcccccac agtgccacat tttcaaatcc atcgatgcga atcgtcattt
    24121 gctcttttaa cggatattgc tgttgataga tttccttccc atcaggatct agtatcgcta
    24181 cattcagctg actgtttttg gctacttgct caaaagacaa atctacttca agtttgccat
    24241 tttgacattt gtcatctaag cgaggtttga tccaaagatc ttctaaatgg ttttgtcctc
    24301 gagcaactaa gaagacatct ctgaagatcc caaaaaatcg gaaaaagtcc tgatcttcca
    24361 agaatgcagc tgtacttctt ttgtaaacct ccacagctag aatattttct tcttccaaat
    24421 aaggtgttaa atcaaattca gacggagtga acgaatcttc ggcatacccg ataaaatgac
    24481 cattcaacca aataaacatt gcttgttcta caccagcaaa atgaatcgag atttgttttc
    24541 cctttagacc ttcttctaat cgaaaagtcg tcaaatacga accaaccgga ttgtctttag
    24601 cagctgaaaa gatcccttcc gcctctttct cagggcttgt cgtgaaaggg ggacggcgaa
    24661 atacatgtcc ctcccacgga tacatcgtat tgatgtaatg gatcttgtca taatttgcta
    24721 attcaatatg actaggaaca gtgatttcat caaaagaaca ggcatcaaaa tcttttttat
    24781 aaaatgtttt tggtcgtacc gaaggatttg gcgaataaca aaaacgccat gatccattta
    24841 aagactgttt aagggaggat gtggtttcta cttcttccct tgttgcataa caaacatgat
    24901 cgctatgtgc atttgattgg ttcactctaa aaacttgtgg atcatctaac cattttatat
    24961 ttgctttcat acttttttcc ttctctctca taactttttg aaatgaagca gttctgtttg
    25021 gaaatcacct tgaaaatcgg ggaagtaaag tccaactgtc atcaattcgg cccccgaaaa
    25081 tatccgcttc gaggtctgtt cctgataaag tgcctcatca tctaacccca tcagatatac
    25141 ttcatggaac gctggttgag ctgaagctag tatcctccct aaaaacacaa tagcttcatc
    25201 ttgtttagga gacacaaaca tccatgcggc aatattttct tcaaaaggac tcgccaaacg
    25261 ataataatgg ccatactgga tcaccggacg aatcgtttga taggatataa tttggtcttt
    25321 tacttgcttt tcttcttcag gagacagctt tgtcaaatcc agttcataac caaaaacagc
    25381 gctcatagct gtttctcctc ttgttttcaa cgaagtagat ctgtcggtct gatgatttgg
    25441 tacagctgat acatgagctg tgatggacga aatcggataa gcaaggcttg ttccatattg
    25501 gattttcata cgctccactg catccgtgtt atcacttgtc catgactgcg gcatataata
    25561 aataaacccg gcatcaaacc gtccacctcc accagaacag ccttcccata agatttccgg
    25621 ataatcagtt gtcaaatgtt caagtagttc ataaagcccg agcatataac gatgcgctac
    25681 ttctccttgt ctctgtgggt caagggtaat cgaatagaca tctgaaagcg aacggttcat
    25741 atcccatttg atgtagtcaa gaggaatcgt atctaaaatc tttctcattt gtttctcaat
    25801 cgtctgccga acatctaacc ttgtaaaatc cagtacatgt tgtgatctgg aagcagaagg
    25861 cattctacct ggctcctgca taagaaaatc aggatgtgtt cgatacagtt cagaatcaac
    25921 cgagatcatt tcaggttcaa accataaacc aaatttcaat cctttgctat gagcataatc
    25981 tgctatttca cgtaatccat ttgtcaactt gccttcatac tcgaaccagt ctcctaatga
    26041 agaattgtcc gcatctcttt ttccaaacca gccatcatct aatacgaaca tttcgatgcc
    26101 tagctccttt gcttcatcaa tgatcgcctt gattttttca ctattgaagt caaagtaagt
    26161 ggcttcccag ttattgacca gaatcggccg ttcagcaaat tgatgacgac ctcttgcgat
    26221 tctttcacgt agcaactcat ggtggatctg actcattttg ttcaatccct gacttgagta
    26281 agaaaggatc atttcaggtg tttgaaaaga ctggcctgca ttcaattccc acgaaaaacg
    26341 atggctgttg atcccaccga cgactctcaa ttgattgatc tgatcttttt caagttcgaa
    26401 agaatggttg ccggaataaa caaattgaag tccgatcgct tctccagtat tttctgtcgt
    26461 atgatgatga actaaagcaa taaagttatt catatggtga ctgctcgttc ctcgacggct
    26521 ttcaaatact tttgttccag ataaaacaga ttgccgtgaa atctgtcttt cattgacatg
    26581 tgctcctggc aaagcaatga cttcatcaaa tcgcctagta tgggcaaagt ctagctggaa
    26641 actagccgct ttttctagtt tgattgtttc tccggtttca tttcttatct ttacagatcg
    26701 tgtgatcact gctctatcag taaatatggt atagaacaaa tcgaaataaa tcgctgtttc
    26761 tctatcctta agtgaaatca ccaacgtttg tgcctctgac ttgtccatca cataagtttg
    26821 aggcaagcct tcgatctctg gcttcccatc tgtaatataa tggctgtcat atctcagatc
    26881 cagtaagtct gatccattct tgcgctgaat gatcgatgcg ggcgttcgaa agtccatgct
    26941 gccatgagaa gagtattctt gcggtagtgt atctttcgac agagaccggt caggatttaa
    27001 gggaacattt cctgaaaatc cacgatctct tcggggataa tttttattgt ctttgtactg
    27061 cttgactggt ttgccaaaat aaatatgcgc caatacattg ctttcttcta tctttatcag
    27121 ataagaaaga aatgtatttc gtaaatggaa gactcggctc ttttcatcaa ataagatgaa
    27181 atttttatct gtttttctat gcgtaatatc catcatttca ctcccaacaa aacggaaacc
    27241 gtttactttt ttttataatt cctgtatact gtttactaaa caattttgtc aataaaaatt
    27301 ttttattttt ttgaggagtg tgtaaaaatg gttggaatta gagatgtcgc acgaaaggca
    27361 aatgtctctc ctgctacagt ttcccgtgtg ttgaataacg atcagacgat ccatgtggct
    27421 cagactactc ggcaacggat agtagaggca gctgctgcgt tggattatga catcagtact
    27481 cgtaaatata tcaaaaagag aatgccttcg attggtgtga tctctacgat cggcaaagcg
    27541 agcgaagaac aggatatcta ttacaaacat ttgcgagtag ggatggaaga agaagctcga
    27601 cgtctgcatt tagggatgaa tcgaatctat aatctatctg ataatcctaa acaatgggaa
    27661 gatctagatc agttaggtgc ggtgatcgtt gttgggactg ttacgaaaga atcgattacc
    27721 gccttgttaa aacaaaacat gcaaatagtc gtcgtggata accctgacat ccagcaagag
    27781 gtcgatatgg tgtatgcaga tcttgaacgg atgactaaaa ccgtactgga attgttctta
    27841 gaaaatggtc ataaaagaat agcctatatc gggggatata aagtcgatat ggatgaattc
    27901 ggtgggaagc agatttctat aaatgaaaag aggatgcgtg cctatcagca ttttatgatc
    27961 gatcatcact tagaaaaata tatgtcttat catctaggtg gctggacaga aaaacaaggt
    28021 gaggtacttg cgactaatct attagaaaat gaatcccctc ttcctactgc cattcttgtc
    28081 gggagcgatc caatggcaat tggtgtctat cgggcattga aacaaaaaaa tatccaaatt
    28141 ggagaagaga ttgttgtagc aagctttgat aatatcgaga caatcgcaaa cctctcccct
    28201 ggcttgacca gtgttcaaat caatgcgaaa tcaattgggc aagcagctgt tcgaatggca
    28261 ttggagcgaa ttgacggtat acgggacgaa ccaatcattt tgacttatcc tgcacgattg
    28321 attgttaggg aaagttttat cccaagaaca aaaaggtatt gaaagagagg ttgtgaaaag
    28381 ccgcttcgtt tcttcatact caaaacgaaa cggctttttc acaacctctt acttatactt
    28441 attcacaaaa tccaatgtct gctggtaaca attttgcgat tcttttagcg tgtaatcaaa
    28501 ttggtattca tgggtaatct ctttttttgt atctgtataa aacaaggatt gcacgggtac
    28561 ctttaattct gtcaaccgat tttctaatgc ttgaccttgc tcctggaatg agtatgcatt
    28621 tccgtcagtt atatacgttg gcggaaattc cttagaaaca tggtcagcca cactagcttc
    28681 tttcaattgc tcactcgttt tccaatcttt tgttccaatc aacgaccacg caacggtttt
    28741 gacgaaaaac ttcataaatc gatcatccga atgctgctgt gctgttagct tcaaatcaac
    28801 aggtccgcaa taagaaatgg ttcctttcag actatctttt ggaagtagct gtttgatttt
    28861 catttgttta gcatacgcat cattcgtttg tatagctgca tattgcaatg cgatttgtga
    28921 acctgcacta tctccaccaa aaaataattg ttccatgtct agcaatttgt cgtctttttc
    28981 ttcagctaat aaatctttga tcagttcatt cacttgaaga acttgattag ggtattctga
    29041 atcaggcgct aattcataat tcatcgcaac cactgcgatg ttggcgtctg aaactaattt
    29101 tgtcgcaaat tctttgacac ccgatttatc tccgccgacg aatcctccac catgtaccca
    29161 aaatagaaca ggaacaggcc ccttgctgtt ttttggatag tagatgtcat aagtattctc
    29221 tttatacttg gactcatacg tcaaatctgt ttttttcgcc acgttttttt ctgcttgatc
    29281 gaacgttttt ttatcagtga tttgaacagt atttgaaaac atatggttga tcaagaatgc
    29341 tccaggtctg ggggaaagct ggaaggcaag aaagattgca aacgcgatcc caagaatgat
    29401 tccgaagaac catccgataa atttaagaat tttctttttc ataaggctcc ctcagtagtt
    29461 agtattaagc attctgatta taccatagtg ttatttccta tcaagctctc ctagatgatt
    29521 taatgatttt ccccaaactt cttctgcaat gcttttgaca aaagaaattt tttccattgt
    29581 tcttcaaaca aaacattttc ttcttctgtt gaagcaaatc cacattgagg acttaagcac
    29641 aaacgatcca aaggcagata tcgtgtcgct tcgtagatcc ggtcaatcac ttgctggtgc
    29701 tcttccattt cgccattttt cgttacagtc aaaatctaag acaactaatt tatcttcaga
    29761 gactttctct aaaagaacaa aactcccagc acgttcacta tcgtattcta aataataggc
    29821 acggacattt tcttgagtaa aataatgggt ctgctacgtc gtcatccccc ctgatgccgc
    29881 caaaatcgaa taataatttc cgcgtcaaac atgtatattt agtgttgaat catttgagaa
    29941 tatgaaaata aaaatctttt tgatcaatca gttaatcaaa ttgaaataac gaaaaatctg
    30001 agacagaatg acgttcattc tgacccagat ttgattttgc acaactcaac agtccttatt
    30061 ggcaaatcgc caaaataatg tagactaact aaaaagacta agaaacaata acaaaagtta
    30121 acacttctta gtctttcttt agcacgtcta tttattaaag attttagggc cttttctcat
    30181 gtttttacga tcattcttag gtgtttccat ttgtttggat cggcctccac cttgtttctt
    30241 tttgatcaat tctttcattt tttctttttg gtccattttt attctccttt aacgaatgaa
    30301 gcgactaatt cgatatgatg ggtttgcggg aaaagatcta caggctgaac tttcttcacg
    30361 gcataacctg cttctgcaaa taacttagca tctcttgcaa aagttgccgg attacatgag
    30421 atatagacga ttcgttctgg tgacatttcg attgctgatt caataaaatg atgatctaat
    30481 ccttttcgtg gagggtcaac tacgatcaca gatggtttga tccctttttc ttgccatttt
    30541 ttcataactt tttctgcttt tccgacttca taatgaacat tttcgatttt attatttaaa
    30601 gcattgaact gtgcatcttc aattgcttct ggaataactt ccatcccata caccttatcc
    30661 actctgtctg ctaaagacaa gccaatcgta cctattcctg aataagcgtc gatcacaatg
    30721 tcttttttat ctaactcggc aaactcgatg gctgtttggt acagatactc tgcttgttga
    30781 gtatttactt gataaaatga ctttgctgag attcgatagg tttttcctaa tagctgatct
    30841 tcgatatagt ctctgccata taaaactttt tctttgtctc ctaaaatcac atttgttttt
    30901 tcttcattga tattttggat gaccgaaacc acttctggca attcttcatg aatagcttca
    30961 gcaatttcct tggatttaaa gaatttttct ttacgagtaa ctaaaacgac catcatttca
    31021 tgggaataat gaccacgacg gataatgatg tgacgaagct gtccttcatt tttttcttca
    31081 ttatatcctc gtacttggaa ccgttgcaag atatctctga ctactttgat tgcttgatcg
    31141 atgacaggat cttggatata aaaatcttcg atagggacta gatcatggct attctttttg
    31201 taaaaaccgg tggctaactg tccatcgata cggcgaacag ggatctgtgc tttattacgg
    31261 tagccgaatg gttctgccat tccgaccgtt ggaagtacag gaacttctgg catcttagca
    31321 atcttcgcca ttacatgctc tacttgtttt tgtttgaaga caagctgttg ttcatacttc
    31381 aaatgggcta aaggtgcgat acctatgcga agtaatgcat tgttttctac aggctgacga
    31441 tcaggtgatt gtgtaataaa tgtttcgact tttccatatc caaacttatt gcctgctttt
    31501 actactagta tttctacttc ttctccaggg agtgcatttt cgataaataa tggataacca
    31561 tcgatttttg ctacccccat tccttcataa ctcaagtcga cgatttcgac tgtatatcgt
    31621 tcgtttttct ttactatttg ctgttctgtc atattttgct cctttaagcc tatttttcaa
    31681 tcctactgaa ctctactata aatcagctaa ttacacaact aaaaccggca ctgaccttac
    31741 tacgttcagc accggctttt gattaattct tttgattagg tgtttcgtct gctatttttc
    31801 cgtcaccgtc gatatcttca tccgttaaac gttcgacttc ttttacgaat tctttgctga
    31861 caacctctaa ttcttcttca tctgtacctg tgattgcttc atcaggaatc tgatcggtat
    31921 tggcaaagaa ctcaatgtgt tgatgaagat tttggaaatg catcggtgct tccccgccgt
    31981 attcaccatc taagttgatc attactggtc gattgatatc atcttctgtt tcaacgaaca
    32041 aactgcttgt tttggtatag attattcttg gatcatcgac atgtcgaccg ccattcagca
    32101 tgagtgctgc aatatgcaag atctcaaaga tatttgctgt cttcacaatg attaaagaaa
    32161 acttcccatc atccaatttg gcatctggcg cgatctgttc gaatcctcca acagagttcg
    32221 tcagccctag gaaaaacatc gaagcatttc cgatatattc cccttcatca tacttcaagc
    32281 gcattttgat tggctttact cgagggagca tctctgctcc tttcgcaaga taagcaagat
    32341 aaccaaaaat actctttagt tctgatggaa cttcataagt caattctgtc aaatagccac
    32401 ctgcagcgat attgatgaag taactgttat cagaaaggcc gatgtccatt tttacggttt
    32461 ggtgtttttt tatcacttct gctgctgctt taatattatc tctaggaatt tttaatgctc
    32521 gagcatagtc gttcgttgta ccagctggga tgatggccat tttaggacgg tgttcaagcg
    32581 gagcgattcc attaaccact tcgttgattg tgccatcgcc accagctgcc actactagat
    32641 caaaacctag ttctgcgact ctacatgctt cattcttggc tgaatctggt tctggtgtag
    32701 ttgcataggc gctggcttca aatcctgctt cttctaatgc ctgtaggata tccgccaaat
    32761 tttttttcaa taattctttt cccgaggtgg ggttataaat tacgcgtgct tttttcattt
    32821 tcagcctcta tcgtttcgct aattcatctt taagtagctt attcacgaca ccaggatttg
    32881 cttgtccttt agttgctttc atgatttgac cgactaggaa gccaaccgca cgatcttttc
    32941 catttttgaa atcatcgaca gattgttggt tgttatccaa aatttcatta atgattggca
    33001 gtagtttgtt cggatcagat aattgcaccc aaccattttt ttcaactact tcttgggctt
    33061 ctccgccatt tgtgatcaat tcacggaaga cttttttggc gatttttgag ctgatcgttc
    33121 catcggcgat caaacgaatc attcctgcta agttctcagg tgtcaatttt gtctcagcta
    33181 attccagttt ctcactgttc aagtaagcag aaacttcacc catcaaccag ttagatgctt
    33241 gcttggcatc tgcaccattt tccaaaacag cttcaaaaaa atcagacatt tcttttgtaa
    33301 gtgtcaatac cattgcgtca tactctggaa gtccaaactc acggatatag cgttcgcgac
    33361 gagaagctgg catctcaggc aaactagctt ttactttttg aatccattcg tcatcgatca
    33421 cgaatttcgg gatatcaggc tctgggaagt aacgataatc actagaccct tctttgacac
    33481 gcatcaaaac tgttttattc gttgtttcgt caaaacggcg tgtttcttgt tggatttctc
    33541 ctcctgaaag aagaactttt gcttgacgtt tttcttcaaa agctaaacct tttttcacga
    33601 aagataaaga gttcaagttt ttcaattctg ctttcgtacc gaactcttct tgtccataag
    33661 ggcgaagaga aatattggca tcacagcgca tagagccttc ttccattttc acatcgctga
    33721 cttctgtaaa ttggataatt gatcgcaatg cttctagata agcgtatgct tcttctggtg
    33781 aacgcatatc agcttcagaa acgatttcga tcaaaggcgt gccttgtcgg ttcaaatcaa
    33841 cgtaagaata accgccaata ccatgcatgt tttttccagc atcttcttct aaatggacac
    33901 gttcgatccg gatttttttc tttttacctt ctacttcgat ttcgatccat ccgtcatgac
    33961 cgattggttg atcaaattgg gaaatttgat atgcttttgg attatctggg taaaagtaat
    34021 ttttccggtc aaaatgagta tctttagaga tttcacagtt taatgccaaa gctgctttca
    34081 tcccgaattc cagcgcagct ttattcatta ctggcagcac gcctggataa ccccagtcga
    34141 tcacgtttgt attgctgttt ggttctgcac caaaatgagc tggcgctgga gagaaaattt
    34201 ttgagttggt ttttaactcg acgtggactt ctagtccaat gactgtttca aaattcattc
    34261 gtctttccct cctaaaatag ctggttgttg tttatggaat tctgttgctt gttcaaacgc
    34321 atatgccgct tgatacatcg ttttttcatc aaaataatta ccgatgatct gcaatccaac
    34381 tggtaatcct tctgataaac ctgccggtac agacatacct ggaagtccag ccaagttgac
    34441 agggatcgtt aagatgtcac tcatgtacat tgtgattgga tcgttaatgt tctcaccgat
    34501 tccgaatgca actgttggtg aagatggccc gatgatcaag tcataatctg caaagacttt
    34561 ttcaaaatct cgtttgatca atgtacggac ttgtcctgct tttttgaagt aagcgtcata
    34621 ataacccgcg cttaaggaga atgtacctaa catgatacgg cgttttactt cttcaccgaa
    34681 tccttctgaa cgtgagttga catatacatc atctaatgat ttcacatttt cagagcgata
    34741 accgtagcgg ataccatcga atcgttgcaa attggaactt gcttctgatg aggcaatgat
    34801 ataataaaca gccacaccgt attttgaatg aggcaagctg acttcttcca caacagcacc
    34861 taatgaacgg aatgtttctg ctgctttcaa tacagcttct tttacgccag gggccacacc
    34921 ttcgcctaag tattctttag gtaaagcaat cttcattcct ttgatgtcgc ctgtcagtcc
    34981 ctctgcaaaa tcaggaactg aaacgcctga agaagtaccg tctttttcgt cataaccgct
    35041 gatagctgtc aatgctaatg cattatcttt caccgtacgg gtcattggtc cgatttggtc
    35101 aagagatgaa gcaaaggcaa tcaaaccaaa acgtgagaca cggccataag taggtttcat
    35161 ccctacgatg ccgttaaaag ctgctggttg gcggatactt cccccagtat cactacctaa
    35221 agaaactgga atttgtccag ctgcaactgc tgctgcagaa ccaccagaag agccaccagg
    35281 tacttttgtt gggtcccaag cattttttgt tttcttgaaa taagaagttt ctgtacttcc
    35341 acccatagca aattcatcca tgtttagctt accaacaggg atcatatctg cttgatagat
    35401 tttatccatg accgttgcat cataaattgg ttcaaaattg taaaggatct tagatgcagc
    35461 ggttgtcaag atatcttttg ttacgatatt atccttgata ccaattggaa taccagcaag
    35521 gacgttgctt tcatcaatcc ctttttcatc taaagctttt gcctgttcca atgctttttc
    35581 ttcgttcaat gtaatgaatg cctcgacctc aggctctgtt tctttgattc gttcaaatgt
    35641 tgtttttgtc aaatcttgta cagtgatttc tttcgataca agcatatgat gcagttcttc
    35701 tagagaacga ttgtgtaatt ctgtcattat gcgccagcct ccccattatc gatgattgcg
    35761 ggtactttga taaagccgtc ttctgtttcc ggcacatttt tcaataattc atcgcggttc
    35821 catccagctt gcgcccgatc ttgtcgcatc acgtttactg tttcaaccac attcgacgta
    35881 aatggaacac cttccgtatc tacttcttcc agcatttcaa ccatatcgat gattttacct
    35941 aattggtcgg taaaacttgc aagttcttca tctgcgaacg caagttttgc taatttggca
    36001 acgtgtttca cttgttcttc actaatcgcc atactacccc ttctttctaa acgagttaaa
    36061 aactttgctc tctattttaa cacaagagtg ccgtgtctga aattgtttat tgaaatttgt
    36121 ctgaaaaaac tcatttttca ttcttctact gagcgacttt tagccaatgc atctgccatt
    36181 tgatcttctg tccaaacttc gattcctaat tcttgtgctt tggtcagctt gctgccagca
    36241 tcttctcctg ctaccacgat atccgttttt ttcgatacgc taccagtcac tttcccgcca
    36301 agattttcga tcgtctcttt tgcttcttca cgagtaaatc gtgttagttt accagtaagg
    36361 actactgttt tttctttaaa aggagactcg acttcttgca attgggcatt tcgaagccct
    36421 ttgtattcga aattgacgcc tgcttgtttt aattcattca tcaattcatg gacttcttcg
    36481 ttactgaaat aagtgactac actgtcggca atgatatcac cgatcgtatc aagcgcaata
    36541 atcgactcat agtcactttt actcaatgtt tctagatcac cgaaatgttc tgctaaaatt
    36601 tttgctgctt tcgctccgac atgtcggatt cctaacccga aaatcaaccg ctcgaccgaa
    36661 ttatctttgc tgttgtcgat tgctgtcaaa atattatttg ctgatttttc ttttattttg
    36721 tccaacgtca ataactcttc ttctgtcaat ttgtaaagat cagcaacatc tgctactagt
    36781 tttttatcat acatctgttc tagtacgcgc ggccccaacc catcgatatt catcgcattt
    36841 cttgaaacaa agtggttcaa accttctttc atttgagcag ggcatttagg attgatgcac
    36901 cgtaaggcta cttcttcatc caaatggaca agttcacttc cacaaactgg acaatgtgta
    36961 ggcaattggt attcttcgct gtctttaggt cgtttatcta acacgacttg cgaaacttct
    37021 gggatgatgt ctcccgcttt ataaatcaga actgtatctt tcaagcggat atccttcaac
    37081 ttaatataat caccgttatg caggctggca cggcttactg tcgttcctgc tactcggact
    37141 ggtgtcatga tagctgttgg cgttactacc cctgttcgac cgactgtcca ttcgatgttt
    37201 tcgattagcg tttcaacttc ttctggcgga aacttgtaag ctgctgccca tctcggtgct
    37261 ttgatagtaa aaccaagttg atcttgtagc gagaattcat tcactttgat gacgattcca
    37321 tcgatttcat agggcaaatc cacacgtttg tcatgatatt cttcaatgta tgaccacact
    37381 tcatcaatcg aatgacatag acgtttttcc cgattcgtgt ggaatccaat tttttctagc
    37441 tcttctagcg catcatactg ggtttttgct tgcataggac cgaaatcagc tactgtgtat
    37501 aaaaaagtgt ccagatttct tttcgctgtg attttagaat ctaactgacg caaagaacca
    37561 gctgcggcgt tccgaggatt cgcaaagata tcttttccct ctgcttctct gtcttggttc
    37621 aattggacaa atgaccgttt tggcatgaaa cattcgcctc ttacttcgat gttcattggt
    37681 tcttttaatt tgattgggac cgaccggaca gtttttaggt tttcagtgat gttttctcct
    37741 acagttccat ccccgcgagt cgcacctctc acgaaatttc catcttcata acgcaaagaa
    37801 acggaaagtc catctatttt tagttcacag caatagtcaa ctacacgtcc cactgctttt
    37861 tgtacacgtt gatcaaaagc tatcagctct tctttgctga aaacgtcgtt caaactgtaa
    37921 agcggaatat catgagtgac tttttcaaaa ccttctaata cttttccgcc tactcgttga
    37981 gtgggagaat cagacgtgat caaatcagga tattgttcct cgattgctac taattctgcg
    38041 tattctttat cataaacata gtcttccact gttggtttat cttctacgta gtattcgcga
    38101 gaccattggt tcagtcttgt acgaagttct tctgctcgtt tagcagcttc gtcaatcgtc
    38161 atttcatgtt ccatcattta ccctccacta ctaagctttt tcaattggcg caaaggcagc
    38221 caaaagacgt tttactcctt gacttgggaa agccacatct agttctagat ccttcgacgt
    38281 cccgcttact cggacgactg ttcctagacc ccattttttg tgtttgactt tatctccagg
    38341 tttccagctg ttattttccc ctccagtagc acttttagag ggaacaaccg ctgtctctgg
    38401 ctgtttatag ctatatgctg tttttttagc gaatacaggc gtttttttag gcgtaggacg
    38461 catgccttcg atttccagta actcctgatc gatttcttct acaaaacgag aaggtcggtt
    38521 atattgcgtc cgtccatata atgttctgga gaaagcattt gttaaataca acgcttcttc
    38581 tgctcgcgtg atccccacat atgcgagacg gcgttcttcc tccagttcgc tttcttccat
    38641 caatgctcga gataaaggaa aaaccccctc ttctagacca atcaggaata caactggaaa
    38701 ttctaatcct ttggctgcat gcaaagtcat caatgtcact tgggaagcat cttcttctaa
    38761 attgtcaatg tcggaaacaa gtgccagatc atttaagaag accgttagtt tttcttctgg
    38821 tgcatcagcg tcttcttcat tttgctgttc gaattgtttg tcgaattctt gtgtgaccgt
    38881 taaaaattcc tccaagtttt cgatgcgtgc ttgtgcttct aatgtatttt ggatttttaa
    38941 gtcttctaga tatccgctac gatccaaaac ctctttcgtc aattctgtca ctgtcaagta
    39001 tgggatcatc tgagtgactt cttggatcat ctctccaaat gcacctaatt gctgtcctgc
    39061 ttttccaccg atatttgcca gatccacatt ttgcgctgct tcaagcagtg gccattcatg
    39121 aagagaagca aaactgcgta gtttttcgat agatcctggt ccgatgcctc gtttgggcga
    39181 attaacgata cgctcaaaac tgattgaatc ttgaggattt accagcacat tcaaatacgc
    39241 taaaatatct ttgatttctt tacgatcgta gaacttgtgc cctccaacca ttttataagg
    39301 aatatttgct ttcaacagag tttcttccat tacacgagat tgtgcgttcg tccggtacaa
    39361 gatggcaaag tcgccgtaat tccgatgatt gcttcgaatc tcttcttgca tccggtctac
    39421 gataaaacgg gtttcgtctc gttcattatc tgcacggtag taagtgatct tgtttccttc
    39481 tttgttttct gtccacaagt tttttggttt tcgattgcta ttgttttcaa tgacttggtt
    39541 tgctgcgcta aggatgtttt tcgtggagcg atagttttgt tctagcaaaa ttactgcagc
    39601 atctggataa tctttttcaa aatccaagat gttctgcata tctgcaccgc gccagccgta
    39661 aatactttga tctgcatctc ccacgacgca caggttccta aatctacctg ccaataaatt
    39721 gactagcgta tactgtgcgt gatttgtatc ttggtactca tctacatgaa tataatggaa
    39781 tttgttttga taatacgtga gtgaatcagg atgttcttca aataatcgaa tcgtattcat
    39841 gatcaggtcg tcaaagtcca tacattgatt atattgaagc tctttttggt aagcagcata
    39901 acattttgcc gcaatctctt cgtaataact gccttgcatt tttgcaaaat cctgaggggt
    39961 ctgcaggctg ttttttgctt gagagattgt tcctaatata cttcgaggat catatttttt
    40021 cggatcaatg ttcagttctt ttagtatccg tttcatcaag gtcagctgtt cagaagaatc
    40081 gatgattgta aagttccggt tatacccgat aaaatcaaca tctcttctta aaatacgcac
    40141 acacatcgag tgaaaagtcg atacccagac atcttcgcct ccagatgcga gaatcgcatt
    40201 gacacgttct ttcatttctt ttgcagcctt attggtaaaa gtaatcgcta ggatgttcca
    40261 aggattgact tctttttcct caatcaaata ggcaatgcgg tgtgtcagca ctctcgtctt
    40321 tccacttcct gcacctgcca ttagcagtaa tggtccgtca gtgtgaagaa cagcttcttt
    40381 ctgacggggg ttcatcccgt ttaataattc agctttggat gacattaaca acatcctttc
    40441 ttttatcaat cttgttaatt atagcatttt cttggctttc attaaactag ctagttcaaa
    40501 atcatttgtt tctttttatg gatttttcct tgtcaattcg ttgatttcgc gctaaattaa
    40561 aagaaagcga ggcgtttgaa tggaaaaaaa aggaaaaatc aagaaattag ataagactca
    40621 gatatatttt attctaaaag gaatatttgt tggactgctg acaggaatcg tcgttagcct
    40681 gtttcgatta tctatcgaaa agctaagcga tttagttcga agtatctatg aaatgagtcg
    40741 ggaacagccg atttacttaa ttggcctagc tatttgctgc atccttgcag catttttcgt
    40801 gggttatctg gtcaaaaatg aaccggatat caagggaagc gggattccac aagtagaggg
    40861 acagcttcgc ggggaattat caatgaactg gttctctgtt ttatggaaaa agttcattgg
    40921 cggtgtactt tcagttggtg cgggcctttt tctaggtaga gaaggacctt ctatacagct
    40981 tggcgcatcc attggacaag gagctggaca attgtttcgg agtccatctt cagaagaaaa
    41041 gattttaatt tctagcggtg caagtagcgg acttgcagca gcattcaatg ctcctatcgc
    41101 aggattactc tttgttttag aagaaatcca tcactccttt tctccacttg tttggctgac
    41161 atcatttgct tcagcaatca ctgctaactt cgtctctctt tactttttcg gcttgagacc
    41221 tgttttatat ctaggtgacc ttccttcttt gccgttgaaa tattatggtt ccttagtgat
    41281 cttaggagta cttctaggca tcttaggttt tatttatcag aatgtcttgc tggctttgcc
    41341 aaaattttac aaccgattgc ctttaccagc ttattttcac gggttcgttc ctttcttgct
    41401 gattttgcca attggttatt tatggcctag tactctaggc ggaggcaatc aaatcgtttt
    41461 agcttttgga catgcttcct tgccaatcat tatgattatc ggtttgtttg ttcttcgatt
    41521 cgttttttcc atgatttctt acggtggggg tcttccaggg gggattttcc ttccgatatt
    41581 gacattgggg gctttaatcg gtagctttta tggaaacatt atggttgatt tcgggatgga
    41641 tccaatctac atcaaggatt ttgtcgttat tgccatggct ggttatttca cagcgattgg
    41701 aaaagcaccg ctgacagcaa ttattttagt gacagaaatg gttggctctc ttaatcatct
    41761 gatgccttta ggattggctg ctcttgttgc ttatatcgtc aatgaccttc tcggcggtaa
    41821 tccaatttac gaatcattat tggaacgtct acttggaaat actcagaccg cctcactaaa
    41881 aggtgcaagg acaacttttg attttccagt aacggcagag agttctttag acggattaat
    41941 ggtacgagac ttcaattggc ctaaaaatat gctgctaatc tctatacgca gaggaaatca
    42001 ggaaatcttg actcacggtg atacgatcat gaatgtagga gatattttgg ttatcttgac
    42061 tgatgaagca aacttgccaa gaatcaagca ggaaatcgag gctaaatctt ctatcacaaa
    42121 tttgaagcaa tcattttaac gaacatggaa aaactatttt acaacaacta ttcatctaca
    42181 ctacttgatt ctatatgatt ctataaaaaa agaagaggct gggaaaaccc agcctcttct
    42241 tttttatttc tatgcttctg ctactgcagg agcttttctc aataaaccat aaatcacacc
    42301 agatacgact gctccgatag caataaacac caaatacatg accgggtgac tcagtaagaa
    42361 tacaacgaaa atcccgccgt gaggagccag taatttgatt ccgaaagctc cgactaatcc
    42421 gccagttaaa gcagaaccaa taataaaact tggaatggca cgaatcgggt cagctgctgc
    42481 aaatggaatc gatccttccg tgacaaacga tagtcccatc acgatgttcg tcaaaccagc
    42541 atcttgatct gttttgctga atttattctt aaacaaacgt gtagcaacga aaattgccaa
    42601 tggaggtacc attcctccag ccataacaga agccatcacg acacttccgc cagttgcaac
    42661 agtcgtagct aaagttgctg taccaaacac ataagcggct ttgttgattg gaccgcctaa
    42721 atctgccgcc atcattccag ctaataatgc accaagtaaa gcagcattcg aaccactcat
    42781 acttgtcaag aaaccgttca atgcatcatt gattgctttc atagggacat tgaccagcaa
    42841 catcaagaaa ccagtaatca gtaagccaaa cactggataa aagaggatcg ttttaattcc
    42901 atccaatgat tttggtaagt tcttgaataa tttacgtaaa aatacgatga cataaccagc
    42961 taagaatcca ccaatcagtg cacctaagaa tcctgcaccg cctgtattag ctaatgcacc
    43021 agcagcaaat ccaacgatca aaccagggcg gtcaccgata cttgaagcaa taaatcctgc
    43081 taataccggc agcatgaaac caaatgcagc ttgtccgatt tggttgaacc agctagcagc
    43141 ttgattgtaa ttccctagat ttgataattg atcatgtggc acgccaataa attggtcgat
    43201 catgaaagaa agcgcaatag cgattcctcc accaataacg aaaggtaaca tgtgtgatac
    43261 gccgttcatc aaatctttgt aaattctttg tccgatagta ccatccgcat ttccttcttc
    43321 tgaactgctt tcttttccat caccatggaa tactggtgca gtaccactaa gggctagatt
    43381 gatcaactct tctggtttac ggataccatc actgacagga cgattgatca gttcttttcc
    43441 gtcaaagcga ttcatctcta cttttttgtc tgctgcaacg attacacctt ctgcacgggc
    43501 gatgtcttca gcagtcaatc ggtttttgat tccttctgaa ccgttcgttt cgactttgat
    43561 ctccacaccc atttctttcg cttttttctt caaagcatct tctgccatgt aagtgtgagc
    43621 gatccctgtt ggacaagctg taacggcaac aacgaatttt ctttctggat gagcagaagc
    43681 ttctgcagct tgtgtttctt gttctgcttt ttcttctgct tctttttgct cttcagctgt
    43741 ttggaacaag tcttggactt cttctggtgt atttgcttct tttaattttc ctacgaaatc
    43801 tgcatcaatc agcaatcgag atagtgctgc taatgcttgc aaatgtgtgt cgtttgcgcc
    43861 ttctggagct gcgatcatga aaaacagata agttggctgt ccgtctaagg cttcataatc
    43921 tactcctttt tggctttttg cgaataaaac tgttgcttct ttaactgcac tgtttttcgc
    43981 gtgaggcatg gcgattccat caccaagacc tgtagaagtt tgtgcttcgc gggctagaat
    44041 tccttcttta tatgtttcga tatcggaaat ccggccggca tcaaacattt tttggaccat
    44101 ttcatcgatt gcgccttttt tatcagtcgc ttgcaaatcc atgatcatcg cttctttgac
    44161 cattaaatcc ttgatattca tgattatcct ccttgaaact aatcaatttt tgtgatttca
    44221 acttctggca gcaactcatc aatcaattcg cgagctgcca agtcatcaga aaaagctgtt
    44281 gcgcttccgc aagcaactcc ccatttaaag gcttcgattg gatctttcgt acggctgtaa
    44341 gccccaataa agccagcaat cattgaatcc cctgcaccta ctgaattttt caatgggcga
    44401 actaatacat tcgttttata agttccttgt tccgtgaaga gcaaagcacc gtctccagcc
    44461 attgagatca gcacattctg tgccccttca gctagtaatt ttttcccata cggaatgatt
    44521 tcttctacag attggaaggt tgtgttgtaa agctcagcta attcgtgatt gtttggtttg
    44581 atcaacaacg gtttcttaac aagtgcattt tttaggtcat cacctgttgt atcaatcacg
    44641 aaatctgcac ctttttctcg aatgatatca atcagttctt gataaaatcc ttttcgcagg
    44701 ctagctggcg cgcttcctga caatacgacg atatctcctt gtcctactgt tcctaatgct
    44761 tgcttcaact catcgatttc ttcatctgaa atagatgggc ctaagccatt gatctcagtt
    44821 tcagtgtctg attttagttt gatattgatt cttgtatctt cttttacggt tgtgaacaaa
    44881 gactggattt gttctttttc aagccacttc gaaataaatt cgccagtgaa ccctcctaaa
    44941 aaccctagtg ctgtagattg agaatcgatc cgtttcaaaa tacgggaaac attgatccct
    45001 tttcctccag gtaacttgaa gtcttccttc attcggttca aatcgcctag ttttaaccca
    45061 tctacgcgta cgatataatc aattgatgga ttaagtgtta ctgtgtaaat cattgtattg
    45121 cctccttaat tgttgtcttt tcacggaatt cattaacgaa ttctaatgga caacgctcgg
    45181 ttatgatcgt ggctgcttcc aaaggtgcaa cagaggtgaa ggacaactgg ttgaatttgg
    45241 tatgatcaat caatacaaat gtctcttcgg aatttttcat ggctaaacgt ttaacagctg
    45301 cctcttctgg atccggagtc gtgaatcctt gttcaagatg ggcaccgttc attcccataa
    45361 atgctttatt aaaatgaaaa ttttttagtt gttctatcgc attagatcct aaaacagcat
    45421 tagttgccag ctttatcgtt ccacctaaaa taatggtagc aagctccaaa tcaactaaat
    45481 ttgccgcatg ttgaacggaa tttgtcacta ctgtgatctg ttttccttgc agaaaaggaa
    45541 tcatttctaa cgtagtagag ccagcgtcta aataaatgac atcttcgtca ttaatggttt
    45601 cagctgccga tttggcgatt tgctgttttt cgtgaacgtt tttgagtgat ttttcactca
    45661 tattctgctc aaaattcaat aattgctctt tcttagctcc gccatgaact ctttctagaa
    45721 acccactatt ctccagctct tgtaaatcac gtcttatcgt tgattcagaa gcattcaaaa
    45781 ggtttacaag atcttgtgat ttcacgattt tctgctgttc aagcaagtct aggatttttt
    45841 gtctgcgttc ctctgtaagc attttcacga tcacctcaat acaaataata gcatattttt
    45901 tttctactag caatataaat cagtcaaaaa cgttcataaa atttataaat cagtcaaaaa
    45961 aaaaataaaa aaccagtcag aaagactggt tttttatttt tttgtctatc atcaagccgt
    46021 tttatcgttt tttattttcg cttcttgttt ttttcatata aacagaagca ggttttcttt
    46081 ccttatgaag aagataataa taaagtccca tcccgccaaa catgaccaaa aaaccgatga
    46141 ctgatcgaat aggaaaatta ggaacaaaaa agagacagac ggataataat gatgccggaa
    46201 ccattattcg ataatagagt tgtttatcca ttttcttcac ctcatatttt ttgtaaagta
    46261 atcaattgtt ctaattctcg gtaatctaaa aattgcacac gcagatgctg ctcacctttc
    46321 ttgacatcga attggatact tcgccgcttt ttctttattc gtttgaaggt aacatcagag
    46381 agtctatgtt tgatttcctt taacggtaat tctgacaggg attctgaagg aacatagatt
    46441 cttaaggata aaagatactc ttgatatttt tcatctgtta cctctacttc tagatattcc
    46501 ctaatataat aacaataagc ttcgattcca ttatccaaag caacagtcgg atcgataact
    46561 ttatagcaca tcatgcgtga tcgattctcg tcaacccaag gaaaatacgc ctgagcattt
    46621 agtgttccgc gaacacgcct ttctttataa tctccttgtt ggatatcata actttttgtt
    46681 acaaaaaatg aagcattctt tttaggaaca ggttgcattt gtgcattctg atactggaca
    46741 gattggatcg tatggtcagt gtaaatgtat tcaacgaatg gcggtttcaa taaaccgaca
    46801 ccattgtccc aagcaagatg atcaaaccca agctggtccc taaaatagga ttgaaacatt
    46861 tgattgtttg gcttttgcca gttaaagggg tctcgataaa gctggataca tatgacttcg
    46921 ttttctaatt ccttcacttt ttctacttgt tggatgtcga gaaaaatcgg tttagggatg
    46981 atttgatgat aatagcgact ataatacatt tcccaacacg aagtgaaaca taaaccttgg
    47041 taaaaaagat cgtatcctgg aaattggttg caatcgacta ctacttcccc gttttgttgt
    47101 ttcattttag gtaaatgttc gatttcatcc tttttctcaa acaatagccg ttgagagatc
    47161 tgttttgtat tgtgatagat aaactcgcta taagctcgca tataggcgaa caccccatga
    47221 gcaatcattt ttttctgaat gaagtctcga atcaaaaatt gcttttcttt gaaaacagag
    47281 atagacaata cattttttat caataattga ttatcttcca agcgaaaact acattcgttc
    47341 tcgtcatttc ctacaactaa ccaactttcg tctcttaccg atgctagcat tattttttct
    47401 tgaagctttc gaagatcata cggatccgct tgttgtgtga aagagcggat aaatgttggc
    47461 tggatcaaca gacgtgtcaa aatagcccaa tcgcttattt cctgtttttt ttcttcttca
    47521 tttaagtctg tgagctggat agtcatcaat aatttatctt cgccaatcat tttctcacct
    47581 ctttcaaatc tttttataat ttaattataa ccaatgataa agaaaaacta aaactttatg
    47641 tcttagaaac caatttggac gattacatga tagactaagt aaaaagaaac aaagaggtgt
    47701 ttacaatggg gttgaaattt gaacgtacag ataatttaga taaacttttc gaatcatttg
    47761 ctgtcgatcc ggaaaaaaca gttgcaccaa aagaagagat cgatcgattt ctaaaaccac
    47821 agccacaaaa tgaaaagaaa aaagacaaga aacaaaagta agttaagctc aaaaaaagac
    47881 ttaccagcca aacttttatg aaagagtttg actggtaagt cttttttatt ctttttatga
    47941 ttcaattgct tgttcgattg ctgcccacgc ttcttctttt ccctgttttg taacggaaga
    48001 aaagagaata aacgtgtcat tgcgatcaaa atccaacgct tttttgattt cgctctcatg
    48061 cttgttccat ttaccacgag ggatcttatc tgccttagtg gcaacaacaa ttacagggat
    48121 atcataatac ttcaaaaatt gatacatctg gatatcttct tgagaaggct tatgacgcaa
    48181 atctactaaa gaaacgacag cacgtagctg gtctctagtc gttaaatatg tctcgatcat
    48241 ctttccccat tttgctcgct cagttttgga tacttttgca tacccatatc ccggaacatc
    48301 gacaaaatgt aatgcgttct cgatcaaata aaaattcaat gtctgggtct ttcctggctt
    48361 accggaagta cgggctaaat tctttcgatc aatcaatgtg ttgataaaag aagatttccc
    48421 tacatttgat cgtcctgcca gagctatttc tggcaattgt gtatctggat attgttttgg
    48481 tgccactgca cttatgataa tttcagcttg atggactttc atggtctctc tccttaacaa
    48541 ggtgatgaat aaagcaagcg gctgtcgcaa aagccaaaat gacttttacg gcagcctctt
    48601 ttcatcaacc cgcttttttc tctgaatctt tatagattac tgttggctca ccagacaatt
    48661 cagctgcttc ttttgtgata atcacttttt cgatgttttc atttgaaggg atatcaaaca
    48721 tcacatccat catgatttct tcaatgatgg aacgaagtcc tcgagcaccg gtattgcgtt
    48781 cgattgcttt tttcgcaatg gctctcaacg cttcaggttc gaattcaagt tcggtattat
    48841 ctagagaaag aagtttttga tattgtttga ctagcgcatt tttcggctca gtcaagatcc
    48901 gtaccagatc atctgttgtc aatttctcta aagctgccat aacaggtaat cgtccgataa
    48961 actcagggat caatccgaat tttagtaaat cttcaggaat gatatgctgc atgacacttt
    49021 cgtcttcaga aagtttttgg ttttgtgtac caaatccaat cgtcttttcg cccatacgat
    49081 tcttcacaat cgtttcgatg ccatcaaatg caccacctac gatgaacaat atgttcgtcg
    49141 tatcaatctg aataaattct tgatgtggat gtttacgtcc gccctgaggt ggcacacttg
    49201 caacagttcc ttctagaatt ttcagcaagg cttgttggac accttcgccg gaaacgtcac
    49261 gagtaataga tacattttcg cttttacgcg caattttatc gatctcatca atatagatga
    49321 tccctttttc tgcaagttcc acattgtaat cagcagattg aagcaattta agcaaaatgt
    49381 tttctacatc ttcccccaca taaccagctt ctgtcaaact tgtcgcatct gcgattgcaa
    49441 aaggtacatt caatgttttt gctaatgttt gtgctaaaaa tgttttacca gaccctgtag
    49501 gtccgatcaa gcagatattg cttttttgca gttcaacatc atctgtgttt tcttgtgctt
    49561 gctgattgac acgtttatag tgattgtata cggcaacagc taacgagcgt tttgcgcgat
    49621 cttgtccaat cacgtagtta ttcaatactt caagaatttc tagtggttta gggacttcag
    49681 tgaattcgcg tacagcttct tcataaaatt cttcatcaat gatttcttta cataggtcga
    49741 tacattcatt acagatgtag acccctggac cagctacgat ctttttcact tcttcttggg
    49801 ttttcccgca aaaagaacag cgtacggtct cattgctact tggattgtca tacatggtct
    49861 tcacccctta acttgcaaaa agtatgcaag aaactatcaa agactttaca gtcttttact
    49921 atcataacat agtttagtaa aaagaaaaag tgtttaacaa aggatcaact gacctatacc
    49981 tttgcatttt ttactcttaa caaaaaataa ggaactgtga caaaatcgtg tcacagtccc
    50041 ttatttcgaa taaacaattt tctagaagta gcttcttcag aaatgattta ttacttgatt
    50101 tctattcttt cgcttctgtc gctgtacctg tgatcaattc gattgctttt ttcattgtca
    50161 catcatgttc cagcatatct tctgtcaaca cgcgtttgat ttgttcgatt ggcatgttgt
    50221 atgtttctga taattcttgg atttctgcat tgatttcttc ttctgttgct tgaagatttt
    50281 cagcagctgc aattgcttcg atcacaagat ttgttcttgt gcgcatttct gcttcacctt
    50341 cgaattgttt atgcaagtct tcttctgtag aaccagttaa ttgatagtac atttcaggag
    50401 agataccttg acgttgcatg ttgttcaaga attcgtccat tgaacgatgt acttcatcat
    50461 gaaccatcac gtgtggcaat tcaacgattt ctgcgttttc aacagccata cggatcgctg
    50521 cttcatcttt tgcatcgtcc gctgcttttt cttttgtttc tactaattct ttgcgatatt
    50581 tttctttcaa ttcgtctaat gttgatactt cgtcatcaac atcttttgcg aattcgtcat
    50641 ctaattcagg cacttctttt gcttttactt catggattgt cactttgaag actgcttctt
    50701 ttccagcaag atcttctgct tgataatctt ctgggaaagt tacatttaca tctagacttt
    50761 cacctgattt atgaccaact aattgatctt caaaacctgg aatgaatgag cctgaaccta
    50821 attcaagtga gtaattttcg ccttttccgc catcaaacgc ttcgccatct acaaagcctt
    50881 cgaagtcgat tactactgta tcgccatttt cagctgcagc atcttctttg ataactaatt
    50941 cagcttgtgc ttcttgttca cgtttgatac gtgcatccac gtcagcatct gttacttcac
    51001 ggtcttgttt ttcaacaact agatctttat attgtcctaa ttttacttct ggtttcactg
    51061 ttacttcagc agtgattacc cagtcttgac ctttttccat gctttcaaca tcgatttttg
    51121 gttgagaaac aggatcgatg ccagcttctt tgacagcagc ttcataagct tctggtaata
    51181 cagcattcaa tgcatcttca tataaagctt cttcaccgta catacggttg aatacttgac
    51241 gagaaacttt ccctttacgg aatccaggta cgttcaagct ttttttcact ttattaaacg
    51301 cagttgttaa tcctttttgg atttcgtctt gcgcaatcgt aaattttaaa acaccatcat
    51361 tcgtgccttt tttttcaaat gttgcagtca tttaattccc tccgagttta gaaattcatt
    51421 ttatacatca aaaacgtttc atgcatacct ttaaatagta cactaaccct ttcaaattgt
    51481 aaacatattg aatggataga atccttgttt ttcataacat ttttatcttt ttcactgata
    51541 aaatctaatg gaagaagatc atttgctgca aaattttttc tctttttttt aaaaaatctt
    51601 gtttttcatc ttctgtacct tcatacatcg tttttcctgt acacgcctct acagtcagtt
    51661 gaaaccagcg cttcgggtct tcgatgtatg tatcatagac aggataaaca attgcagatt
    51721 gcaacgtgaa ttcttctttt aacacggaac taagcagcgc atcttcattc ccgtaacgat
    51781 ctgaaaatac acataattgc tggtaacttg cctgctgctg cggctttggc agatcttttg
    51841 gtatgacttt gactaacttt tcttcaatcg tcaaatagaa aacaggatgg cattcgttca
    51901 attgcctaag tgtctccagt aattttgccc ttgctaaaat atggacctct ggcgatacaa
    51961 taagtttact cgctgtttgg ataaactcat gataaggaag ctgttcgatc tcatcaatag
    52021 acgcaagctg acgtgcaggt tccaacgaag gaagttcctc cgatttattg tggagtgcct
    52081 tgatcttctg cctctccatt tgtccggata attcttctgc aaattggatt ttttcaatga
    52141 cccgctgctc gaaagcttca taaaaatctg tacttgctat caattttcta gcatataaaa
    52201 aatcttgtgt actgattaac aagtcaaaat aaaattcagc aaactcctca ttttgaagat
    52261 actgtttttc atgcaagagt gcttgcttca atgcttcttt tttctcgtcc aactcgtaaa
    52321 gacaaaaaac aagcaggcta ttagcctcaa agctttcttt caactcgtaa gctcgttgaa
    52381 ataattcttt tgcctgctga tattgctggt ttgctagtgc ttgttgtgcc actcgcatta
    52441 aattctcata tttttctgga aaatcaatcg gcttcacgca gtgtcctcct cttgctcata
    52501 ttcagctcat gttcaatagt agcaaaacaa aaaaagcatg acaattaaaa ataactgaag
    52561 caccctctaa aagctagatt ttagatctga cttttagaag gtgctttcaa ctgttactgc
    52621 tttttattgc tcatcagctg ttgacttcct ggttgaacgc tttgatcaga ttgatcgtaa
    52681 caacacttgt attagtgaaa aaatcgccca gatgttgctt tttctgatta aagactgctg
    52741 gaagataccc taacatcagc aaaggaaatt ttagaatgaa ccggcaagca ccttctctaa
    52801 ctaaaacggt tgaccagcta agttcttctt catcaaagct gatgactcga ataccaaaga
    52861 tcattttccc aatcgtttgg ccatgattga atttcgtcaa taaaataaaa tacgctagat
    52921 aaataagtaa ggctgtgaat ccgtagagac tcagataaga atctgaaaaa ttaagccaac
    52981 ctagattttt ggcaatacca agtgttaaac gcgtaatagc tccgatacac aaaagatcga
    53041 ccaagaaggc aaacattcgg ataaaaaaac ctgcatagaa atacttagga aaatcatttg
    53101 cttttggcgg ttcatttctt gtgtccgtat actttttcca tttacgttgt ttctttttga
    53161 tttcttcggg cgtcaaaggc tctctttcaa aagagctcag taccttttgg gaaaagttgg
    53221 agtcaggtcc tacagcaggc tgctgttgct tatctttttc ttgttcctta ttttcatttg
    53281 aaagctctga catgcttact cacctccgta ataatacatt gcttttggtg attccgctgt
    53341 ccctagattc tcaagaacgg ataagatctg actagtctca gaaggcttca atccctggaa
    53401 ttctgctagt ttacttccta accatgtact agcaaaccca gatggcgtgg aagaatattc
    53461 tactagttcc gcatcttcaa gctgttgttc ctttcgtata gcttttaaag catcttcagg
    53521 aaatcccaat tcatcgacta aacctacttc ttttgcttgg acaccatcat aaatccttcc
    53581 atcagcaatt tttttgactt cttcttcaga tttattccgt ccctcgctga cgattgctac
    53641 aaaacgacta tatgcgctgt cgatatatgc ttgaagcacc gcttcttctt cttttgtctc
    53701 tggtcgcgtt cctgaaccca tatctttcaa cgctccgctt ttaactgttg tatcttccac
    53761 acccagtttt tctagaagtc ctgaataatt caatcctgac atgatcacac caattgagcc
    53821 ggtcactgtt tcttctgttg caaagatttt atctgcttga gcagaaatat agtagccacc
    53881 gctagctgcc atgtttttca tgctgacata cattgggata tcatgttctt tacgaatcgt
    53941 atccaatttc ttagcgattt ccgcactttc gtagacaccg ccaccaggag aatttacttc
    54001 taaaaagata cctttgactg ttggatcttc ttcaatcgcc ttcagttgtt ccataaaatt
    54061 tttatgattg taaccttcag aagcaaataa acctgaagac cctcccgcag caatcgttcc
    54121 atctactgat aattttacga ttttttgcgt actgtctccc ttttccaaca catttggagc
    54181 tagttcttca tccccatata accaactgtt caatccctca atttgatcgt tttcctgagg
    54241 cttagtcaaa ctagctgaaa ctaacgaaac cacaaataat cctgcagcaa tcagaactgc
    54301 tgcccaacgt cttttattca ttctttctcc tttctaatac aagtttttta tgacgatcac
    54361 agtttctgac tgctcagaag tgtcgaaccg ctctgctttt tcttcccgcg catacccgga
    54421 aaacgactct tttgttaatt catcttctac cgtaaactca cgagcttgag caacttccaa
    54481 ggcatcaggt gcgatttctt ggatgctatc ccagccagta tctaaaaata ttttcgtatc
    54541 atctgataca ccagctgatg cttcgaattt ggacaattgt ttttttaaca ttcccagtgt
    54601 catgatctca atttttgaat ccatttttac tcctcctcta tccgattact ttctattgta
    54661 ccgaactcct gaaaaagatg atagataaaa acccattatt ttttgacata aaaaggacat
    54721 ttgacaaaga atttgatata taccaattta ttttttattc tttttttgtt gacaagaaca
    54781 ttcgcaaaag gttatgattt taaatgtttc cagataaaaa acaaaaagga ggatagttat
    54841 accttttagg atagcgccag gtctgtgtaa acagatgacg aggagagggt ttatcgaaag
    54901 attcggcgga tggccctagg gactgcactc tacagaaaat ccacaaaaaa tgtctgcaaa
    54961 gataaaacaa aaggattttc ctgcagctgg aagcattcat acgaattcat tatagaaagt
    55021 aggatgtttt ttatgtgcgg aattgttgga atgattggat taaaaaatgt aacaccagga
    55081 ttgattgacg gtctagaaaa attagaatac cgtggttatg attcagctgg tatctttgtc
    55141 tcagatggca caactgatta tctggtcaaa gcacaaggca gaattcaaaa tttgaaaaac
    55201 aaaataaata ttgatactac aggaaatata ggtattggtc atacacgatg ggcaactcac
    55261 gggcaacctt ctgaagaaaa cgcccatcca catacttccc aaagtggacg cttcgtgctc
    55321 gttcacaacg gcgtaatcga aaactttgaa gaacttaaaa ttgcttattt agcaaatgac
    55381 cactttattg gtgagaccga tactgagatt atcgctcatc taattgaaac tttcgcgaag
    55441 gatactacaa cgcaagaggc gtttttaaaa gctttgcggg tcatcaaagg ttcttacgct
    55501 ttcgctttga ttgatcggac agcacctgat gttatttacg tcgctaaaaa taaaagtcca
    55561 ctattaatcg gactcggcga tggattcaat gtgattgcca gcgatgcaat ggctatgctt
    55621 gctcatacga aggaattcgt tgagattgaa gatgaagaga tggttaccgt cacatcagaa
    55681 aaagttatta ttcaaaattt tgcaggtgac atcgtagaac gttcttcatt cgaagcacaa
    55741 gtagatgctt cagatatcga gaaaggtacc tatccttttt atatgctgaa agaaatcgac
    55801 gaacagccta ttatcatgcg tcgtatcgct caaaaatacg taacagaaga caatcgtgtc
    55861 tctcttgatc aaaagctggt cgatacattg tctgatagcg atcgaatcta tatcgttgct
    55921 tgcggaacta gttaccatgc ggggttagca ggtaaacaga ctttggaaaa attgacacag
    55981 attcctgttg aggttcattt agccagtgaa tttggctata acacacctct tctttcaaaa
    56041 aaaccattct ttattttctt gagtcaaagt ggcgaaacag cagacagccg ccaagtgctg
    56101 gtaaaaatca actgtctcgg ctacccttca cttacgatta caaatgttgc tggttctact
    56161 ctttcgcggg aagcatcctt tacactgcta ttgcatgctg gacccgaaat cgcagtagca
    56221 tcaacgaaag cttatactgc acaaatagct gtactaactt tattagccaa agctatcggt
    56281 gataaaaaag aatttgaaac ttctcttgta ttcgatatca ctcatgaatt gagtttagtt
    56341 gctaatgcga tggaatcggt catcgcccaa aaagattatt tagaagagtt ggcagaagta
    56401 tatctcagcg atacaagaaa tgccttttac attggacgtg gtgctgacta caacgtttct
    56461 cttgaagctg ctttgaaatt gaaagaaatc agttatatcc aggcagaagg ttttgccgct
    56521 ggcgaattga aacatggaac gattgctttg atcgaagaag gaacaccagt gatcggaatc
    56581 atcagtgaag aagtgactgg tgcgcatact cgaggaaacc tgaaagaagt cgaaagccgt
    56641 ggcgctaaaa cactagttat tgtctcagag ggattagaaa aggaaagtga ccagctggtg
    56701 ctaccaactg tccaccctta tctaactact ctaaccacag tcgtaccgac tcaattactt
    56761 gcatattacg caacgctatt acggggattc gacgttgaca aaccacgtaa tttagcgaaa
    56821 tcagtgacag tagaataata aaagaacaag gaccagtgtc agacatctga cactggtcct
    56881 tgttctttta tttt
//
LOCUS       DAFBSV010000006        56387 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.006, whole genome shotgun sequence.
ACCESSION   DAFBSV010000006 DAFBSV010000000
VERSION     DAFBSV010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.006"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            330..1175
                     /locus_tag="LLB18_000407"
     CDS             330..1175
                     /locus_tag="LLB18_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBK5243438.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="LLB18_000408"
     CDS             1456..2676
                     /locus_tag="LLB18_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HBK5243439.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="LLB18_000409"
     CDS             2673..5393
                     /locus_tag="LLB18_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK5243440.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="LLB18_000410"
     CDS             5377..6321
                     /locus_tag="LLB18_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBK5243441.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6390..7400)
                     /locus_tag="LLB18_000411"
     CDS             complement(6390..7400)
                     /locus_tag="LLB18_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBK5243442.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7580..7924)
                     /locus_tag="LLB18_000412"
     CDS             complement(7580..7924)
                     /locus_tag="LLB18_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBK5243443.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7917..8351)
                     /locus_tag="LLB18_000413"
     CDS             complement(7917..8351)
                     /locus_tag="LLB18_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HBK5243444.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8489..9226
                     /locus_tag="LLB18_000414"
     CDS             8489..9226
                     /locus_tag="LLB18_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5243445.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9219..10430
                     /locus_tag="LLB18_000415"
     CDS             9219..10430
                     /locus_tag="LLB18_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5243446.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10634..11416
                     /locus_tag="LLB18_000416"
     CDS             10634..11416
                     /locus_tag="LLB18_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HBK5243447.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11486..12148
                     /gene="trmB"
                     /locus_tag="LLB18_000417"
     CDS             11486..12148
                     /gene="trmB"
                     /locus_tag="LLB18_000417"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBK5243448.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12246..14000)
                     /gene="ade"
                     /locus_tag="LLB18_000418"
     CDS             complement(12246..14000)
                     /gene="ade"
                     /locus_tag="LLB18_000418"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBK5243449.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14132..15061
                     /gene="tadA"
                     /locus_tag="LLB18_000419"
     CDS             14132..15061
                     /gene="tadA"
                     /locus_tag="LLB18_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HBK5243450.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            15018..16067
                     /locus_tag="LLB18_000420"
     CDS             15018..16067
                     /locus_tag="LLB18_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HBK5243451.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16064..16342
                     /locus_tag="LLB18_000421"
     CDS             16064..16342
                     /locus_tag="LLB18_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBK5243452.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16317..16787
                     /locus_tag="LLB18_000422"
     CDS             16317..16787
                     /locus_tag="LLB18_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBK5243453.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16804..17106
                     /locus_tag="LLB18_000423"
     CDS             16804..17106
                     /locus_tag="LLB18_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243454.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            17123..17494
                     /locus_tag="LLB18_000424"
     CDS             17123..17494
                     /locus_tag="LLB18_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HBK5243455.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            17466..17825
                     /locus_tag="LLB18_000425"
     CDS             17466..17825
                     /locus_tag="LLB18_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243456.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17997..19004
                     /locus_tag="LLB18_000426"
     CDS             17997..19004
                     /locus_tag="LLB18_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBK5243457.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            19029..20213
                     /locus_tag="LLB18_000427"
     CDS             19029..20213
                     /locus_tag="LLB18_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBK5243458.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20650..22233)
                     /locus_tag="LLB18_000428"
     CDS             complement(20650..22233)
                     /locus_tag="LLB18_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBK5243459.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22811..22954)
                     /locus_tag="LLB18_000429"
     CDS             complement(22811..22954)
                     /locus_tag="LLB18_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HBK5243460.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23177..23656)
                     /locus_tag="LLB18_000430"
     CDS             complement(23177..23656)
                     /locus_tag="LLB18_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBK5243461.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23729..24013)
                     /locus_tag="LLB18_000431"
     CDS             complement(23729..24013)
                     /locus_tag="LLB18_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243462.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24091..24285)
                     /gene="ssrS"
                     /locus_tag="LLB18_000432"
     ncRNA           complement(24091..24285)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="LLB18_000432"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24357..25643)
                     /locus_tag="LLB18_000433"
     CDS             complement(24357..25643)
                     /locus_tag="LLB18_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBK5243463.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKSAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25781..26452
                     /locus_tag="LLB18_000434"
     CDS             25781..26452
                     /locus_tag="LLB18_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBK5243464.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26418..26906
                     /locus_tag="LLB18_000435"
     CDS             26418..26906
                     /locus_tag="LLB18_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HBK5243465.1"
                     /translation="MKKKGLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26919..27866
                     /gene="prmA"
                     /locus_tag="LLB18_000436"
     CDS             26919..27866
                     /gene="prmA"
                     /locus_tag="LLB18_000436"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBK5243466.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27867..28631
                     /locus_tag="LLB18_000437"
     CDS             27867..28631
                     /locus_tag="LLB18_000437"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBK5243467.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28864..31077
                     /locus_tag="LLB18_000438"
     CDS             28864..31077
                     /locus_tag="LLB18_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBK5243468.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31088..31534
                     /locus_tag="LLB18_000439"
     CDS             31088..31534
                     /locus_tag="LLB18_000439"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBK5243469.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31705..32964
                     /locus_tag="LLB18_000440"
     CDS             31705..32964
                     /locus_tag="LLB18_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HBK5243470.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33053..34000)
                     /locus_tag="LLB18_000441"
     CDS             complement(33053..34000)
                     /locus_tag="LLB18_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBK5243471.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34394..35686
                     /locus_tag="LLB18_000442"
     CDS             34394..35686
                     /locus_tag="LLB18_000442"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBK5243472.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35701..37470
                     /gene="aspS"
                     /locus_tag="LLB18_000443"
     CDS             35701..37470
                     /gene="aspS"
                     /locus_tag="LLB18_000443"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBK5243473.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37579..38454
                     /locus_tag="LLB18_000444"
     CDS             37579..38454
                     /locus_tag="LLB18_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBK5243474.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38720..40603
                     /locus_tag="LLB18_000445"
     CDS             38720..40603
                     /locus_tag="LLB18_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBK5243475.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40678..40962)
                     /locus_tag="LLB18_000446"
     CDS             complement(40678..40962)
                     /locus_tag="LLB18_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBK5243476.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40952..41686)
                     /locus_tag="LLB18_000447"
     CDS             complement(40952..41686)
                     /locus_tag="LLB18_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBK5243477.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41815..42438
                     /locus_tag="LLB18_000448"
     CDS             41815..42438
                     /locus_tag="LLB18_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBK5243478.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42630..43751
                     /locus_tag="LLB18_000449"
     CDS             42630..43751
                     /locus_tag="LLB18_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBK5243479.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43758..46886
                     /locus_tag="LLB18_000450"
     CDS             43758..46886
                     /locus_tag="LLB18_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HBK5243480.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46905..50099
                     /locus_tag="LLB18_000451"
     CDS             46905..50099
                     /locus_tag="LLB18_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HBK5243481.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50245..50952)
                     /locus_tag="LLB18_000452"
     CDS             complement(50245..50952)
                     /locus_tag="LLB18_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBK5243482.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            51717..52115
                     /gene="spxA"
                     /locus_tag="LLB18_000453"
     CDS             51717..52115
                     /gene="spxA"
                     /locus_tag="LLB18_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBK5243483.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            52447..53100
                     /locus_tag="LLB18_000454"
     CDS             52447..53100
                     /locus_tag="LLB18_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HBK5243484.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            53326..54324
                     /locus_tag="LLB18_000455"
     CDS             53326..54324
                     /locus_tag="LLB18_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HBK5243485.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            54500..56308
                     /gene="pepF"
                     /locus_tag="LLB18_000456"
     CDS             54500..56308
                     /gene="pepF"
                     /locus_tag="LLB18_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBK5243486.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT        18554 a         9729 c        11686 g        16418 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttcttt tattttgatg aatcagttgt ttcttcagtt
     6421 gaagattctt ttgttgaatc agttgatttt gtgtcagaac tctttgttga agctgtagtt
     6481 tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg cactcaacac attttcaaag
     6541 gcatcatctt tgatttttac atttgcatct tttaattctt caccgattac tttagttgtg
     6601 aatgcattgt cacttagttt agtttcagta gcgatatctt ttagttgatc tttgtattta
     6661 tccatgtcat tgcctttatt ttggtttttc accattttga caacgtagta ttctgtcgca
     6721 taagaagtag gatttgttgt agtaataaca tcggagatct caccgtcttt caatttgaaa
     6781 gctgcttctt ttacttctgc aggaatagtt gttgtcgttg agtcgaattt aactttaccg
     6841 ccatcttctt ttgtctctgt atcagttgat ttgtctttgg ctaatttaga gaaatcatct
     6901 ccatcatccg ctgatttttt cacatctttt gcttcatctt cacttgataa tttgatgatt
     6961 tgtgcttcta cttctggatg gaaagatttc caagcagttt tcaaatcgtc atctgtaata
     7021 tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt tacgaatata ttctttataa
     7081 gtatctttcg tatatccagc agcttctaat tgtgattcaa aagtatcacc taatgatttc
     7141 gcttgtttgt cgtattctgc atccacttgc ttatcggtta ctttatcgcc atatttgtta
     7201 ttgaatactt tataaatgat catccgttgt actaaggatt ggttcgatga ttcaagtttt
     7261 gcttcatcat agaaatcaga tacagtgatc gttccgcctt tcatcgttgc gatatcttta
     7321 ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca acgcactagt agctgccaaa
     7381 ataattgatt tttttttcat taaaatttgc actcctgtaa ttagttatta tttttatata
     7441 ttaactatac catatcccat ttcctttaaa aacgttgtcg tggtagtttc aaacaaaatt
     7501 caaaatttca tcacattcct aggaaatacg caaacttttc tcacttatat agttaaatct
     7561 gttgagaaaa taatcattat tatatttgtt caggatactc tggcagatca gcttttagtt
     7621 tttctacttg ttcattgatt tgtgtgatac gtggttcggc ttggaattta aaatcttcga
     7681 tatctttttt gattgcttct tggaaagcag gaatcacaga ttcagctgtt tcttttgttt
     7741 cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa atcatttgtc agagttgttg
     7801 cttcttccaa ttcttcgatc agtttctttc ttgtttcatt cccgctcctg ggcgccaata
     7861 acagacctcc gacagtgcca gcagcagctc caaataacag tcctttgaaa aagtttttaa
     7921 tcatcgcagg acacctgctt tacgattgtt tcttgaatag cttttagttc ttccgatcca
     7981 taactatctt gatgattgac aaagtgaata gaaaaatcat cctctttgct gtagcgaggg
     8041 actaaatgga tatgtgaatg aaaaacagat tgataggcta gttcacggtt gttattcaag
     8101 atattaagac ctttcatttc tggaaaagct ttttccaatg cttgagcaat cttaggcaca
     8161 cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa aaatatctgc tacatgacgt
     8221 ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga tgtctaaaaa agcatagacc
     8281 ttgtcgtctt catatatttt atagcttggg atttcttgat tgatgatttt gcaaaaaata
     8341 cagttttcca tataaaacat cctttctata aagaataaat acttcagctt aactttacca
     8401 taagttaaag ctattgtaag gaaaaaaaca aaataccgtc attttcttcg tggtataata
     8461 aataaaaata aatggcggag gaaaaagaat gagtttaatt atcgatcatg tcacaggggg
     8521 gtacggacat ctccctgtgt taaaagatat cagtttcgat gtacagcctg gagagatagt
     8581 agggttgatt ggactgaacg gagcagggaa aagtacgacc atcaagcaca ttatcggtct
     8641 gctggaagct tcaaaaggaa cgatagaaat caatcatcta tccttaaaga aaaatacgga
     8701 agaatatcgc aaacaaattg ggtatattcc agagactcct tctttatatg aagaattgac
     8761 attgagagaa catatcgaag tcactgcgat ggcctacgat atacctatgg atatagcaat
     8821 gaaaagagca gaaaagttgt tggagacttt tcggttatct aatcgtcttg actggttccc
     8881 agctaatttt tcaaagggaa tgaaacagaa agtgatgatc ttatgcgcct ttttgatcga
     8941 gccttcttta tatatcatcg acgaaccatt tttaggcttg gatccactag ctatcaatgc
     9001 attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc ggtattttga tgtctacgca
     9061 tattttagct actgcagaaa aatattgtga tcgttttgtg gtcttacata acggagagat
     9121 acgagcagac ggttctcttg agatgttgag aaaagaattt cagctgccgg attcttcttt
     9181 ggacgaaatc tatattgctt taacaaagga gcaggcacat gagtagtttt tttcaaaaac
     9241 gtttagcaag acatcaaaag aaaatgatga aatatatgcg ttatgtattg aacgatcatt
     9301 ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt atattattct aattggttga
     9361 aaaccctgca gccaccgttt gcaattggag ggctcataat ctctgtattt tggatgctct
     9421 gtttattcgt gggtaagatg gctacttttg cagaggcagc agatattgtt tttttacttc
     9481 ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt tcgctattct tgcatttttc
     9541 cgttgatctt tttgatattg gcatgcggat tggccatgcc attagtggtg gttagtacgg
     9601 agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt atggagtttg aaattcagtc
     9661 atctgcaaat caagagagca gaattgtttc gactagatca acaagttatt cgttattgga
     9721 aattaggctg gtttttttct tctctgatct ttttgtttct atcattttat tggctaatat
     9781 gggcaggaat agcaggtgca ttagtacagg caagtctata ttactggttt ttgtggaagc
     9841 aacaagaaaa aggattggat tgggagaaaa tggtgcatgt agaagaacat aggttgcatc
     9901 agatctatca atttatcaat ttattcacag atgttcctga aattacggca aagatcaaaa
     9961 gaagacgcta tttggatcct atattgactc atattaaaag agaatcaaaa aacacttatc
    10021 tttacttgtt tgcaagaaga ttggcaagag gttctgattt tagtggtctt tatttccgat
    10081 tagtaattat aggtgggtta ttgattgccg gagtagtcga cttttatttt agtctgatta
    10141 tcggtttctt atttttatat ttgatcggtt tccaactgtt acctttagcg aaccagttcc
    10201 gctatatggt tctcgttcag ctttatccaa tccataagaa tcagaagaag caggcgattc
    10261 agtatctact cacatgggta ttaattatcg cgtcggttat ttttggtttg attgctgcag
    10321 tcgtattaga tgggcagcag cgatgggttc cgctagcggc ttatttgatt gttactatgc
    10381 tctttgttaa actatatgta ccaactcgtt tgaagaagat gtcagactga aaacaaagct
    10441 gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca gtaagaatgc tgttcgttct
    10501 attttttttg agaaaagctg gttttttgaa tggcaattaa atgaaaaaga acgtatatgt
    10561 gcttgacgtg tagtgttcag gcgactagaa taataagtac tgcaaaacaa agagtaagag
    10621 gacgggagaa tgcatgatgg agtttcagtt agaccaagag tggcggttac gtcccatcaa
    10681 aggcgacaca ggaaaaacat acataggcat gcgtgatgag gacaaagtct ttattaaacg
    10741 aaacacgact ccgatgttgg ctgctctttc aagggaagga attacaccaa aacttgtttg
    10801 gacaaaacga acggggaatg gcgatacttt gacagcacaa gagtggctgg aaggtcgctt
    10861 gctgactcct aatgagattg gtcaaagaaa cgacgtgatt gatgttttgt accatttaca
    10921 tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt ggtcgtgtca tgacgccgga
    10981 gaagatgctg caaaaatatg aaaaagaatt accggaagaa ctccagaaaa atcaatttct
    11041 gcaaattgtc catcgttttc ttcgtgagca gatcccgtca atagataagg aaaacttatc
    11101 agtagtacac ggagatgtaa accatcgtaa ttggttagta tgtaaaaatt atttatatct
    11161 agtcgattgg gattcaatca tgtttgcaga ccctgcggtg gatattgcaa cgattttagg
    11221 aaattatgtg ccactgtcta gctggaatca gtggctgatc agttatggca tacgcccgac
    11281 tgacgaaatg cttgaaaaat ttcattggta tgcggccatg aatttgctcc aagaaatcac
    11341 cagatattgc aaacgtgaag atcatcgacg gatgaacgaa gaaattttac aattaaaacg
    11401 aattttcagt ggctgaggtt tggcccaaac tctgcggaga tttggccaga cctttttaat
    11461 tagaggaaag gaatggagat aaataatgcg tgtccgaaat cgtccgggag cagcggaaat
    11521 gttagcggct cacccgaatt ttgtaattag tgatccaaca ttgtggaagg gaaaatggaa
    11581 tgaattgttt gaaaacgatc atccaatcca cattgagatt ggtatgggga aaggccagtt
    11641 catcactgga atggcaaaag cccatcctga aatcaattat attggagtag aaatgcaggt
    11701 cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa ccgcttccta acctgaaact
    11761 tctacatgtg gatggatcag cgttgacaga gtatttcgct gacagcgaag tagatcaaat
    11821 ctatctgaat ttttccgatc catggccaaa aaaacgtcat gaaaaacggc gattgacata
    11881 taagactttt cttgctgtag atgaacagat tcttcgtcca aatggagaaa tccatttcaa
    11941 aacagataat caaggattgt ttgagtattc tctggcaagt ttttctcaat atggcatgat
    12001 cctcaaacag gtatggttag atttacatca aagtcaattt gaaggcaata ttatgacgga
    12061 gtatgaagaa aaattttctt caaaaggtca acgtatttat cgagtagaag ctcaatttca
    12121 agataagacc aaaaagaaaa gtctgtgaaa ctaactttct gctttcataa aaacattaat
    12181 atccataaat aaatcccaga aaatgaacat tacagatgta atgtattttc tgggatttat
    12241 ttgatttaaa atgtatttat ttcatcggtt tttccacaag gtggaatcaa ttggaagcga
    12301 gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg gtatgacaga taatgttaag
    12361 aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc ctagttgatg tgctttagtt
    12421 attaattcat tcaactgttc atagacgatc gaaaaaggtt cctgtgtcat gattccgcct
    12481 ataggaagag aaacacaagc tatttcctgc tgtttgttga caacggtcat cccgccacct
    12541 ttttgaatca aaagattagc agcatacagc atatcctcgt cgtttgtccc aacgacaact
    12601 agattatgcg agtcatgggc aatcgttgtc gctatcgctc cttgtttcag ctgaaatcct
    12661 ttcactatgc ctaatccaat gtttcccgtt tgatggtgac gctcgatcac cgcaatcttt
    12721 aattggtctt tttcgattga aggaatgaat cgttcgcctt gtcggtccac tttttctacc
    12781 aaatctttag tcactagact attcgggata atttcgatca catgggcttg tgaagaagaa
    12841 agaagcagct ctaacgaatg tggatttaat ggttgagcgt ttagttttgg cagacaacac
    12901 gtatatgaat ttgaatgatc agcaaataaa tggtcttgga gttgcccaga ttgaacaact
    12961 aatgttccct tatagaaaac ttcatgaatt ggcagcttgg taagatcgtc tgttaagaag
    13021 aaatcagctt gatacccagg ggcaatcgca cctagtgttt tcaaatcaaa acattctgct
    13081 gcattcaatg ttgccatctg aatggcttgt aatggatcga ttccaagtgc aatagcttga
    13141 cggacgatat gatcgattga tccttctttt actaaatcat tgatcagttt atcatcggtg
    13201 acaaagaagc atcttcttga attttcaggt gtgatcgccg gtagtagcga tgccagatct
    13261 tttgcaacgg tcccttctcg aaccattaaa tacataccaa gatccaaacg ttctttagct
    13321 tcttttgcag ttgtagcttc atgatccgtc cgaatacctg ctgcaggata aacatttaac
    13381 tcttccatgc cgataccagc tgcatgcccg tcaatttttt tcttatgctg gtgcatcaat
    13441 tggatctttt ctaggatgtc tgtttcatta tttgctactg cttgatagtt catgacttca
    13501 gctaagccta aaacttcggg tttttgtaaa aaaggggcta atttttttgc atttaaattt
    13561 gcaccattgg tctcaaaagg ggttacaggt acacaagaag gtagcataaa aaagatattc
    13621 atgagtgttt gtcttgcatc ttctatcata aactcaagac ctgtactccc agcaatgttt
    13681 cctatttcat ggggatctgt cactacagta gtaactccat gaagcaagga tacttttgaa
    13741 aattcgcttg gtgataaaag tgagctttcg atatgcacat ggccatcgat gaatcctggc
    13801 actagatatt gcccattagc attatgtacg ctttttcctt cgtattcacc gattcctacg
    13861 atcattcctt cgcagattgc tacatctttt tccatgattt ctttcgtaaa gacgttgacg
    13921 atcttagcat gcttgatcac taggtcagca ggcttttttt tacttgctac ttcgatatat
    13981 ttccttaatg ttgtttccaa tggagtgcct cccaagataa atttttataa gtataacata
    14041 aattcggttt ttgccaatat ttttttgtaa attcatttta tttgaaacaa aaagatcaaa
    14101 aagacgtatg ttttttgtgg aggggagaat aatggaaata aaacgattat cggatcaaat
    14161 gataagtgaa agttttgcca aacatgccca agacgtatat atattgccag cttcagaagt
    14221 attttacatc tattttcgct atggaaaaaa acgaacattc tggaagaaag tctcttcggc
    14281 agatggacag caactgatct caagatttaa gtatttggga cagatggata tcggagaaaa
    14341 aagaaaagct cagttaggtg catttactta ttctttagaa aaacaggaag ttcgtctgcg
    14401 gttgtcttct gtaggagatt accttcaacg agagagttta gtgattcggc tattatacgg
    14461 tacttttgaa acaccccatc gttgctttag ttctcgagat tttgcaacta ttttacagaa
    14521 aaccgtcaga cgtggattat accttttcag cggaccagtc ggatcaggca agacttctct
    14581 aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt actatcgaag atcctgtaga
    14641 gatagaagaa ccgttttttc tgcagctaca gatcaatccg aaaatagcac agacttatga
    14701 tacacttttg agactcgcat tacggcatcg tccagacttg ctaatcattg gcgagataag
    14761 agatgaatca actgcacatg ctgcggtaag agcagcacta acagggcacc gggtttttgc
    14821 aaccgtacat gcacgcaatc ttgaaggtac attggtcaga atccatgaac tgacaaagaa
    14881 aaaagaagag ctatctgaat gtttagctgg tgtcatttat caagaacttt tggaagatgc
    14941 caatcaccat ccttctgttt tatggagtta tcaatttatg gaggaagaat cagtaaaaaa
    15001 atcatgggag gaaagttatg aagaagctca ggaaaatatt tggcagtcag aactattcta
    15061 aaggattaac aagaagccag caaaaccagt ttgcacaaac catgggagaa ctgcttttat
    15121 ctggttttag tctgcaagaa tccctttatt tattactcac gatccgttcg tttccacctg
    15181 ttattttggc aaatatccaa catcagctaa aggaagggca agcgtttagt gaggtacttt
    15241 cgcaaatagg atatggagca gagcaactgg tacagatcga gttagctgaa cgtcatggga
    15301 atctgccgac aactttgttg gaaattgcca aacagtttcg gcttgttgaa ggatttcgca
    15361 atgatttgaa aaagctgctt gcatatccga tgctattgct cacctttttg ctaggtatct
    15421 tgtttagtat gcggttgttc gttttgcctc agcttattgg ttcaggaatg gtcatgcaag
    15481 agcattgggg tattcagctg atacaagtct ttcattggta tgttctacta ttcatcctag
    15541 cggttactct attggcttta ctagtaaggt atcgtctgat gaagttgtct cctgttgatc
    15601 agagtgaatg gataagcaga caattattga ttggaccgat atattccttg tatcaatcgg
    15661 cttatttgtc actagagatt ggaaagcttt ttcatgaagg tttcgaatta aggcaaatca
    15721 tagtctgctt aaaggaaacg aaacaagaaa gtctgattca gcatcttgcc tctaagttga
    15781 ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt ccagaattat cgttttctat
    15841 cagaagaatt cagtaaaatt gttttacagg gagaggcaaa gggaagttta ggtaaagaac
    15901 tgatttttta cagcgaatgg acaagaaaac agcttttcaa acgtcttcat cactggatgc
    15961 attttattca gccaatcatt tttttgggcg tagcggcttt gattttatta gtttatgccg
    16021 ctgttttatt acctgtttac ggaagcatag aggaggtttt gccatgaaaa agagaaaaat
    16081 atcttattat agcggtttta cattgatcga aatgctaatc gtcttactga tcatcagtgt
    16141 attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg aatcatgtag accaagaaag
    16201 tcgtgaagcg atcatccagt tggtagacac acaaaaagag ctctatgcgc ttcaaaataa
    16261 tggaagagtt cctactgtgg aggaattgtt gaatgaaggc tatatcaaac gagaacatgc
    16321 agaaatctat cagcggcctt gaaggtaagg ttttagcatc aggatatacg ttgtttgaat
    16381 cactcttact gattttatta cttacaacga tcctttcttt tccagttctc gcattttctg
    16441 catggaagaa tgaattggca gtctatcaat ttttcggcca atttgaaaaa cgaatctatt
    16501 ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg cttttattgg aatagtgaag
    16561 agaatcaaat catttttcat gttccgaatc cagataaaat aaattgggaa gtattagata
    16621 ttcctgatga gattaccttg aaacgccatg cttctattac ttttgctgct agaaccggga
    16681 atgaaagttc actaaaagct tatcaatttt attgggaaga aaaagagcgg acgattacgt
    16741 atcaattcca gatagggagt ggtcgctata caaaaagaat tgaataaaac aggatttgtt
    16801 ttgttggagt cccttacagc gcttatgatc gcttctgtct gtgtctactt agtgagcttt
    16861 ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg aggaactgct atttattcga
    16921 atgatttatg aagatatcaa gacgcagcgg atgtatcaca aaagaccaga gcgaagggaa
    16981 gaaatgatcc catacgatat ccaaattgtc gataataatg gagtaatcga aaaagtgttt
    17041 gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa gtaattccag catttacgct
    17101 gattgaatgt ctaattggac tgatgatatt gagcagtcta ttgctcacat tcaatctttt
    17161 gattcagcaa accatccaag taagtgaatt tttgcagcgt aaagatcaaa aagagtggct
    17221 aatattttta gcacaattag aagaagaact caagagcagt cacaatgtct ctgtgaaaaa
    17281 tcagcaactg cactacacga tcgaggataa acagtatatc atcgaaagat atcaggcaat
    17341 gatacgtaaa agaagaactt ccggcggaca tcaacctatg ttaacaagta tcactgagct
    17401 tcaattattg gaaaaagaac acacaatttc tttttatgta cactttgaaa atggagaaga
    17461 tggatatgcc atatggacaa aaaacgatca gtagaaaatg ttataagggc tctattttat
    17521 tttctgtctt gcttttattt cttttatgta cgtttttatt gatggcagca ttagaaagct
    17581 accgtttgtc aatggatctt aatatacgaa tcaaaaatta ttatatagca aaaataatga
    17641 agcagatggc tttatcggaa cagtctacgc ttgccgaaag ttcggaagga gttttttact
    17701 acacaactgg atctgtaaca tatcagtggg tacaacagtc cctattctta gaggtggaag
    17761 tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa tgatacagat actagtacag
    17821 aatgatggaa tgttcgtgaa aacgccctct tttctgttat aacactgttt ttaataaaaa
    17881 aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat tgaaattttg tcaattgttc
    17941 gatagaatta aacaggtgaa aaaattgtta taatatatct agaaatgagg tgcaccatgt
    18001 taccagaaaa aatggaacaa gggtttaatc aaaacctgga agctattcag cttttacaga
    18061 atgcattggg aacttccttt ttagaagcct atgtcgaaaa tgcagaaaat ttaatagatg
    18121 attatcaagt acgtgtggtg gatggagtgc cgacaaaaga gacaacgcaa cggatcacag
    18181 ctctttatga agagttgaag aaactttctt tcgagccaga agaatggcgc agactgtctc
    18241 aattactttt attgaagggc agccagacag aacatttgca ggcgaaccat caactcactc
    18301 ctgatagtat cggtttttta tttgtttttc ttattgaaca actatacaca aataaaaaag
    18361 caccggttaa gattctggat attgcggcag gaatgggcaa cttgttatta acagttcttt
    18421 taaacctatc gaatgcgggg taccaaacag aaggaattgg tgtggatatt gatgatacat
    18481 tgttggctgt cgcagcttct acaagtgatt tgacacaagc aaatgttcaa tactttcatc
    18541 aagacgggtt gcaggaatta ttaatagatc ctgtcgattt tgcaatcagc gatttgccaa
    18601 tcggttatta tccgaatgac gaaaaagcaa aagagttttt aacaagtacc gaagaaggcc
    18661 atagttatgc acatcattta ttgctagagc aatcaatgaa atatgtgaag ccggatggtt
    18721 ttggtttgtt tttgatgccg agtggatttt tagaaacgga tcaaagtgaa gaaatcaaaa
    18781 aatggtttaa agaagaaggt tatcttcaag gaatgattca attgccagat gaattgttcc
    18841 gtaataaaca atcgcaaaaa agtattttga tcttacagaa aaaaggacca caagcacaac
    18901 aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa agaaccagag aaggtgacgg
    18961 aatttttcaa cgagtttaaa aactggaaat catctgctct gtaatcattc aacgagaagg
    19021 agagtcatat gtctaaaaca attgcaatca atgctgggag ttcaagtttg aaatggcaat
    19081 tatatcaaat gccagaagaa accgtagttg cgaaagggat cgtcgaacgt atcggtttac
    19141 aagattctat ttttaccatc aagtacggcg ataatcaaaa attcgaacaa atcatggata
    19201 tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca gttgattgaa ctgcaaattt
    19261 taagctctta tgatgaaatc accggagtag ggcaccgtgt tgttcacgga ggagaaactt
    19321 atggggattc agtagtgatc gatgagaaag taatggaccg cattgctgaa ttagcagaat
    19381 ttgctccttt gcataatcct gcaaacttaa tggggatcaa agcgtttaaa aagattttac
    19441 ctgacatttt gagtgtggct gtattcgata catctttcca ctcaacaatg ccaaagcaaa
    19501 attatttata tagcttaccg gtgtcttatt atgaagattt caaagtaaga aaatatggct
    19561 tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc aaaattattg aacaaaccga
    19621 tcgaagaact aaaaatcatc acttgccact taggaaatgg tgtatcgatc acagcagtcg
    19681 atggaggtaa atccatggat acttctatgg gattcacacc attagctggg gtgacaatgg
    19741 gtacacgttc aggtgatatc gatccagctg ttctcccata tttaatggaa aaattagaga
    19801 ttgatattga tgaaatgatc aatgttttga acaagaaatc tggtctgcta ggcctaacag
    19861 gattgtctag tgatatgcgt gatcttgaaa agaactatga aaaagaacat attcgtttag
    19921 cttatgacat tttcgtggac cgcatccgaa aatacatcgg cggttatgtg acaacgatga
    19981 atggtgttga tgcaattgtc tttactgctg gtatcggcga gaatgacgga catgtacgta
    20041 gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat cgatccagcg ttgaatgaat
    20101 tgcgtggtga agaagtagat atctctacaa aagaatcaaa agtaagagta ttagtgatcc
    20161 caacagatga ggaactaatg attgcccgtg atgtggagcg tctgcgcggc taagccaaag
    20221 cattcgttag gataaaagat gaaacgcatg caagagggaa ttcttgcatg tgtttttttt
    20281 gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc cttctttttt acaggatctt
    20341 cttagggaat tttgcttgga aaagtggtca aaagggaaaa gactggcatt ttatttattg
    20401 attttcagga aaatcccaat attttatttt cattcatctt tataagggac attacatatg
    20461 taaaaagaaa aaacattttt agatcagcct cgtgggctgt cgactttatt cttcgcttta
    20521 tgtttagcta gaaaaccgat ccgaaacatt cattgatcga ataataaaaa cttgattttc
    20581 cacctgtact ttgcctgaat cgtgaaagca caggtatgaa aatcaagttt tttgttgcga
    20641 aaaaacgtcc tagtcaatca gttggccgag cggctggcgg ctgatctgct cctgatcaat
    20701 aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg tcatggctga ctgctaggag
    20761 cgttccttga tagtcttgca gcatttcttc aatttcttct cgagcatagc tgtcgaggtg
    20821 attggttggt tcatccaaaa tcaggacgtt gattttttct aaaaagagtt tcagcaacgc
    20881 caaacggatt ttttcaccac cggataaatc tttgatccgt ttacccacat cgctttgata
    20941 aaagccactt ttggctaatt gccgtcgagc gacttcttcg tttccagtca atgtgatggc
    21001 gtaagccagc aaacggctat cgggatcggc aaactgcagc tgctgcggca aataaccgat
    21061 ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc ttttcctcac cgagtaataa
    21121 tttgagtaag gttgattttc ctgcaccatt gtcgccgatg atggctaaat gatctccacg
    21181 atagactgca aaactgctgt ctttgaatag tacttgatca gcgtactgct ggtgcaagtt
    21241 ttgaatgatg aaaacttctt tgccagattt tccaccatta gacaagcttt gcagccgatt
    21301 tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc aggcggcgtt ccagttcttt
    21361 ggcttttttg aagaaggact cattgtctcc ttcatgtgcc cactgacgaa aacgacgaat
    21421 catgactttc aaccgctgga cttctttttg ctgcagttcg taattttttg tcagctcagc
    21481 caagcgagct tctttcaaga ctcgaaaacg gctgtagttt ccgggatact caatcaatgc
    21541 accttcttcc agttcccatg tttttgtggt gacttgatcg agaaattgcc gatcatgaga
    21601 aacgaccaga accgattttt ttgtattctg taaatagttt tccaaccagc gaatactgtt
    21661 aagatctaaa tgattggtcg gttcatcgag taaaagtaaa tcggcatcgg ctgctaaaat
    21721 tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt tctgttaacc gtgcttcctg
    21781 acggtgtgga atccctaagc cttgcaagat cgctgcaatc cggtcttcta atacgtaacc
    21841 gcctagttct tcaaagcgat gctgcagctc accgtaacgg gccagacact tctctaagtt
    21901 tgtatctggt tctgtcatca atgcttcgta gcgactcatt tgctgtttga ggtcctgtat
    21961 ctcagcggca gaatggagca agtagtggtt gacggtcgct tcggaaactg taagttcttg
    22021 ttcgaccgtc ccgatcttta agcctttttt gcgactgata acaccgctgt cgacaccttc
    22081 tctgccggtc aagatttgta aaaaggttga tttgccagtt ccgttgatac cgactaaggc
    22141 aattttttca ccagcttcaa tttgacagga taaatcctca aataatggat tcccgccgat
    22201 tgttttttta atagaaattg cttgtatgat catgatctct ctccttgaga ccactcaaaa
    22261 aggccatggt tatccatggc ctgtgttatt taaactcaga ttatcatgag aaaaatacct
    22321 tgagatggcc attgatttta cgtgaattca actgttttgg acaaacttgt cccgtcaaca
    22381 gcaactgtaa aaccaattgc atggctaaat gcgatatggt atcgttggta attttcatta
    22441 cttgttattt tagtcatgcg catcatagta ttttccctcc ttcgtgtagt tgtcttttcc
    22501 agtgtacctg aaagtgtcag aaagttcaac tagcgctgac atttacttaa tatttatcga
    22561 tgtgtaattc tgtcagagag ctttttttat ctgactgagg gtaatgtctc gtggaccaca
    22621 tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca tatggtgttt gataaaaaac
    22681 tttgtctaca tgacttcctt ttgccatttg cttaataccg ttgcattaaa cagctcttct
    22741 ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt gtggttgcaa tggcaagcgg
    22801 tagcctttca tcaattcttg aatgatttac cgaatgtagc acttgccttc tcgcggtacc
    22861 cgaacccgaa ataaaatttt agtttggcga taaaatcggt atccgccatc gatacttcat
    22921 attttttcgt atcagattca tcggaaactt ccacattgac gaaccaataa gctttggcat
    22981 gcttaggtcg ttttaaacca caccagggcg actaatcgcc ctggtgttca ctttttttta
    23041 ttttacttga actcattgac tgttttccct ttattttaaa cattataaag accgatgagt
    23101 gcttgccgcg tcttttgttt ttatcacggt tttttgtgca aaaaaacctg ccgatagttg
    23161 gcaggtcgtc tacgtgttaa gctttggtgt ggtctttagc tggcaattgg ttttctaaat
    23221 cagttcggac aacaagcaca tcgcaagctg cgtttctaat aacatattca gaaacagaac
    23281 caataaataa acgttctaca gcattcaatc ctgtggctcc taacataatc aaatctactt
    23341 gattatcttc tgggatttct ctggcaataa tttgttttgg tgagccatat tctacgacag
    23401 aggttacatt attcaagcca gctttcttcg cattgctttc ataatctgcc aatgtttgct
    23461 ttgccatttc agtagcttgt tctgcaagca ttccatcaaa ggatgaaacg gtttggaaag
    23521 aacgtgtgtc aatgacatgt gctaatagaa gttctccgtt atttcggata gctacattga
    23581 ccgccttttt aaaagctaat tcagcttcat cagaaccatc tacggcaacc atgatttttt
    23641 tgtattgttg taacataagc attcactcct caagtcaatc gtattgtact cttttattgt
    23701 agaacacttt agggaaaaag agaattattt actgctttgg ttcagcaatt ttttttgcaa
    23761 atcggatact gaaggtggca gaaacaataa ttacgatcag taaaaagacc aaggcaataa
    23821 agcgttgatt gaaaaaagct gttaaaatac ccattacgcc taaaacagca tatgcagctc
    23881 cgtaaaattg taggaatcct tgatttttat catttttgtt gatcaataca aaaaagatat
    23941 cctgtttatt aaataaataa tagctaacga ataataatac taaagtggcg ataatcatta
    24001 aaatcctaat catgaacaaa tcctccaaaa taagcaacaa atagaaaaag caatttgcca
    24061 agagcaaatt gctttattct ttaaaagatg gtaatctccg ttaatgccgt tgtttgtcct
    24121 gtagtattga tcccgcgaat tcaagcaggt gggtcccatg gtcgtagctt cgaactacca
    24181 aatgataagg catgttacca gcagtgacac aagacgggtc ccaagatatc aataaaaatg
    24241 ttcggtcaac acacaaagag gacaattcga acatcacaga tttcccacct ctatagtagc
    24301 atatgaattt aaaaagagca atgagagagc tcgcagaaac agaaccgttt tcttgtctag
    24361 ttttttggag gatgcttttt ccactctttt atacggtaat actgttgacc cagagcctgt
    24421 tcatatttcc ctgtatcttt tggctgataa tactgagcac tcttcagttt atctggtaaa
    24481 tattgctgat tgacccaagc ctgatcaaaa tgatgaggat actgataacc cacgccacgg
    24541 ttgagtgatt tcgcaccttt gtaatggcta tctctcaaat gatcaggaac atctccagct
    24601 ttgccctctc gaatatcagc aagtgctgca tctaatgcca tgtaggcaga attggatttt
    24661 ggcgacaagc aaagatcgac gacgacgtct gctagtggga tacgtgcctc aggcaatccc
    24721 aatttttcag cagctaatac agcgttcact gtacgagccg cagcagcagg attacctaaa
    24781 cctatatctt cataaccgat aaccatcaga cgccggcaaa tacttgccag atcacctgcc
    24841 tcaactaaac gggcgagata atgaagtgca gcatccacat cacttccacg aatcgatttt
    24901 tgaaaagccg aaataacgtc ataatgagca tctccatttt tgtcatgggt aagagctttt
    24961 ctttggacac attcttcaat gatcgacagt gtaagatgaa tccttccttc tttatctgaa
    25021 ggagtcgata gtgtagccag ttccagccca ttcaatgcac tccgcaaatc gccgttcgtt
    25081 gcacgcgaaa ggtgaagaag agcatcttcg tctaactgga ttgcttgttg tccaaggccg
    25141 cgttctttat cccttaaagc atgttcgact gccaactgga tgtcttgttc tgttaatggt
    25201 ttgacttcaa agatctgtgt acggctgcgg atcgctggat tgatggtaat ataaggattc
    25261 tcagtagtcg ctccgatcaa gatgattcgg ccactttcta aatgaggaag cagaaaatcc
    25321 tgttttgttt tatctaatcg gtgtacttca tccaataaga ggatcactgt accactcatt
    25381 tttgcttctt ccgctacaac ttgtagatcc ttttttgaat ctgtagcggc gtttagcatg
    25441 cgaaatgcat aattagtaga gccggcgatc gcacttgcga tactcgtttt tccagtacca
    25501 ggaggtccat atagaatcat ggaagagagc atgcgagcat cgaccatgcg gcgtatgatt
    25561 tttccttccc cgactagatg ctgctgacca acgacttcat cgatcgttcg aggtctcatg
    25621 cgataagcca atggctgttg cataggattt tcctccttct tgtttttacg tcccttaatt
    25681 atatcatatt tagcaagatg cctagaaaga acagccttct gttgttttgt tttcatagct
    25741 tatccaacta atattgtgta tgataaagta ggtgagaaaa atgacggata aacaaaagat
    25801 agatgaattt ttttggaata aaacgacgcc agaagtggca cgggatttat tggggatgta
    25861 tttggagcat gacacaccag aaggaagatt agctggatat attgtagacg cggaagcata
    25921 cctaggtcca gaagacgagg ccgcccatag ctatggttta agaagaacac cgcgtgtgcg
    25981 ggcaatgtat gaaaaaccag gtacgatcta cctttacacg atgcatactc atcggatttt
    26041 gaacatcatt actcagccag aagggattcc tcaaggagta atgatacgtg caatcgaacc
    26101 cgccgcaatg attgatcaaa tgagtaaaaa tcgtggcgga aaaactggtc cagatatcag
    26161 caacggtccg ggaaaattag tggaagcatt agcaattcct caagaacttt atggtcagtc
    26221 tatagcagat agttcgttac gcttagtttt tgagaaaaaa aagacaccaa aaaagatcaa
    26281 tgctttgcct agaatcggta tcccaaacaa aggtgtatgg acagaaaagc cgttgcgttt
    26341 tgttgtgtcg ggaaatcctt atatctcttt acaaagaaaa aaccaaatcg agaaagattg
    26401 gggttggagg aaagaaaatg aaaaagaagg gtctattaac atatttagat gaaataattg
    26461 aaaaacaagt gacagactat gatgtagctt tagattggga tacaaaaaat catacgatcg
    26521 agatcgttgt tcgcttgttt gcagaaaata aagcacaatt tgagattgat gatgcagaag
    26581 ggatcgtttc gcaagaacca attatcgaat ttgaagacgg cgtacttctt tttaatcctc
    26641 agaaatctgt ttttgatgaa cgcaattatc tagcagtaat cccttatgaa ggaaaaaaag
    26701 ggttggcaaa atcagtagct gattctttag tggaatatct aaatgaagta ttagctcaag
    26761 ggcaaagcga tttgcttgat tttttggatg aagacgatga cgaagctgta ttcgagcttc
    26821 actgggataa tcagcaacta gcagaattag tagaagtaaa acagcaaaat gaagcagata
    26881 cttatttacc gtacccaagt tattaaggag tgacagatat gaaatggaat gaagtaaaag
    26941 tagaaactga aagtgaagca gtcgaagcag ttgctaatat tttgatggag gcaggggcga
    27001 gtggtgtcgc gattgaagat tctttagatg ttgaacattt tcagtcggat caatatggtg
    27061 agattttaga taaaaatgat tttacatcgc tgaaagaagg cgcactagtc atggcttatt
    27121 ttccggaaac gactttctta ccggaaatct tgccttttat caaagatcgt atcacacaat
    27181 tacctgagtt tggtctagct attggaaaaa ataaagtaac agttagtgaa gtagaggaaa
    27241 gcaactgggc aacagcctgg aagaaatact atcatccggt gcgtattacg cgaatgctga
    27301 cggttgcgcc aagctgggaa aactaccaga cagaagatcc tctagaaaaa attatcacac
    27361 tagatcctgg tatggcattt ggcacaggca ctcatcccac gacttccttg acattgacag
    27421 cactagaaac agtcttgcgt ggtggtgaaa cattgctaga tgtgggaact gggtcgggcg
    27481 tgctaagtat tgcagcaaaa tatcttggtg caaaagatgt ctatgccttt gatttagacg
    27541 aagtagccgt tcgttcggcg aaagaaaata tggatatgaa tgaaatagcc aaagatgtcc
    27601 atgtatcagc taacgatctt ttgacaggaa tcgagattga aagtgatgta atcgttgcga
    27661 acattttagc agatatcatc ttattgatga tcccagatgc ttggcgttta ctgaagcaaa
    27721 caggcacgct gatcgtttca ggaatcattg aagagaagaa gcaaatggtt ctggatgcca
    27781 tgttagaaca agggtttatc gtggatcaaa ttttccagca aaaagactgg tatgcaatta
    27841 ttttgaaaaa accagaggtg gaatagatgc agcggtattt tttaaaagaa tcatatgaat
    27901 caaaagacta ttttgtttta gaaggggaaa actatcacca cattgtacgg gttatgagga
    27961 tggaacccga ggatgaagtt tttttggcat tcaatgatca aatagccatt gttgcagaaa
    28021 tcacggagat tactgaagag gctgtttatc tgaaagaaat taaaaaagaa gaaaatcaaa
    28081 aggaactgcc aagttcgatt accatagcga gtggctatcc taaaggggaa aagctggatt
    28141 ggatcgttca gaaatccact gaattaggag cgcaagcttt tcttggtttc ccggcatcag
    28201 cctctgtcgt taaatgggat gcaaaaaaac gtatgaaacg acaacaacgg cttgaaaaga
    28261 ttgctcaaga ggcagcggaa caatcccatc ggcagatcgt gccatcagta gagttattgg
    28321 aaacgaaaca agatttattt gagcggctag atgattatga cgtggtcttg gttgcttatg
    28381 aggaatcagc aaagcaaggc gaaaaatcaa atgcagccaa aattcttagt gaaacaaaac
    28441 cagatagtcg aatcttagct gtctttggac cagaaggtgg attatcccgc gatgaagtcg
    28501 attattttgt agaacacaaa gggatacttt gtggattagg accaagaatc cttcgtacag
    28561 aaacagcacc tctttattta ttaagtgctg ctagctatca atgggaatta atgaatcctt
    28621 ctttcagcta acgttcttca ttaataaaag agtatcgaca gaaagaattg aaaaaatagt
    28681 caacaatttg tataatagaa acaattattt atacaatgga tacgaaaaat cgtttgaaaa
    28741 agcttttaaa aagcgaacat ttccgtaaaa aaacgtataa ctgcacggat tttgggacaa
    28801 ttatcaaaca gatatttgtc ccgattcccg ttttaccgaa aaaagaaagg gggatcgatt
    28861 cctgtgacaa aagaagaaat tttaacggga cccggtgtca taaagctcgt tagtcaatac
    28921 atgggtcccg aacatgtagc atttgttgag aaagcatgcg aatacgcgac tgctgcacat
    28981 gacggacagt ttagaaaatc aggcgaaccc tacattattc atcctatcca agtcgcaggt
    29041 atattagcag atttaaaaat ggatccccat acagtggcta caggcttctt acatgatgtt
    29101 gttgaagata cagaaatcac tttagaagat ctgagagaag aatttggcga tgacgttgct
    29161 atgttagtgg acggcgtaac caaattaggg aaaataaaat ataaatccca cgaagagcag
    29221 ctagcagaaa accaccgaaa gatgctgcta gcaatggctc aagatttacg agttatcatg
    29281 gtcaaattag ctgatagact acataacatg cgtacgttga agcacctgcg agaagataag
    29341 caaagaagga tcgctcagga aactttagaa atctatgcgc ctcttgcaca tcgtctaggg
    29401 atcagccgga tcaaatggga attagaagat acagcacttc gttatctaaa tccaaaacag
    29461 tattaccgta tcgtccactt gatgcagacg aagagagaag aacgtgaaaa atacgtaagt
    29521 ggtactgttg aagatattcg aatagcgaca gaagagctgg ggatttttgc agaaatctat
    29581 ggacggccaa aacacattta ttcaatctat cgtaaaatga aagatcagaa aaagcagttc
    29641 aacgaaattt atgacttgct agctattcga gtgatcgtag attcaatcaa ggattgttat
    29701 gctgtattag gagcaatcca cacaaaatgg aaaccaatgc ccggcagatt taaggattat
    29761 attgccatgc caaaagctaa tatgtaccaa tctttgcata ctaccgtgat cggtccggca
    29821 ggaaatccgg tagaaattca aatccgaaca caggaaatgc atgaaatcgc tgaattcggg
    29881 gttgctgcac actgggccta taaagaagga aaaaatgaaa aagtagaacc agatggtatg
    29941 acgaaacaat taagctggtt ccatgagata ctcgaacttc aagacgaaag ctatgatgct
    30001 tctgaattta tggaaggcgt aaaaggagat atctttagtg ataaagtcta cgtcttcaca
    30061 ccaaaaggag acgttactga gttaccaaaa ggatccggac cattggactt tgcatacagt
    30121 atccatacag atatcggtaa caaaaccact ggtgcaaaag taaatggcaa aatggtgcag
    30181 cttgattaca aattgaaaaa cggagatatc attgagatca tgacttctcc aaattcattt
    30241 ggcccaagtc gcgactggtt gaaattagtt gctactagca aagcaagaaa taagatcaaa
    30301 cgtttcttca aagcccaaga tcgagaagaa aatgtgatca aaggccacga atccgtggtc
    30361 aaatgtatta cagatctagg atttacgcct aaagatattt tgacgaagaa caaactgcaa
    30421 gaagcactcg atcgttttaa ttatcaaaca gaagatgatc tctatgcagc tgtagggtat
    30481 ggagaagtta gccccttgac gatggccaat cgtctgactg aaaaagaacg taaagaacaa
    30541 aaaatcgagc agcaaaagca agaagcagaa gaaatcatga atcagccgaa aaaagaacct
    30601 gacaaaatga aagtacgtca tgaaggtggc gttgtcattc aaggggtaga aaacttacta
    30661 attcgtatca gtcgctgctg taatccgatt cctggtgatg atatcgttgg ttatatcact
    30721 aaaggcagag ggatatccat tcatcgtcga gattgtccga atgttcagcc tgacaaacca
    30781 aatgtagcag aacgtttgat tgaagtcgaa tgggaagata catcgaatac acgaaaagag
    30841 tatgatgcag atttggaaat ttacggctat aatcgttcag gcttattgaa tgatgtactt
    30901 caaacagtca atgcgctaac gaaaaatctc aacagcgttg aagcacggac gaataaagat
    30961 aaaatggcga cgatccattt gacggttggt atccagaatt tatcccacct aaagagtatc
    31021 gtggataaaa tcaaagcagt acctgatgtc tacagtgtac gccggacgaa tggataggag
    31081 gacagatatg agagcagttg ttcaacgggt aagtaaagct gctgtgtcag tcgatcagca
    31141 agaaattgga aaaattggct acggcctact tgttttatta ggcattcatg aaaccgatac
    31201 gcaaaaagat gtggactatc tggtaaaaaa aattgcacaa atgcgtattt ttgaagatga
    31261 acaaggaaaa atgaatatta gtgtagaaga tgtgggagga caaattttaa gtatctctca
    31321 attcacactg tttgcggata cgaaaaaagg aaatcgacca agctttgtgg aagccgcacg
    31381 accagaaaca gctattcctt tatacgaatc attcaatgaa ggaatcagaa gtcgcggcat
    31441 cacagtcgct accggacaat tcggagcaga tatgtcggtt tctctcgtca atgatggacc
    31501 tgtaacgatc attattgatt ctaaaaacaa ataaagtaat ctggttttca ctagtaaaaa
    31561 ctatgaaaca cgtcgcttaa gttagactga taaactctaa cttaagtggc ttttttgtct
    31621 gcaaaaagcg cttcttttgt cagcagtcgg aaaaaaagtt aagcttaaat tatacaagtt
    31681 attttttata ggaggttgct gaagatgaaa gaagtaccag tagtagatat caaaatcaca
    31741 gatttaaaaa aattgtatca aaaaggatac aacatgttgg aggagttacg ccatgaagcg
    31801 gacgctcccg tcgtcaaagc aaagattttc aataaagaag ctatcacgat ctacggatca
    31861 tcagcagcaa aagtatttta tgatccaagg aatttcaaac gaaaaggtgc tatgccaaaa
    31921 ttagtattga agacactttt tggtcaaggt ggagtacaga ctttggatgg agctgctcat
    31981 caccatcgga aaaatatttt tatggatcta atgacaccgg aaagaatgga agattatcat
    32041 cgtatcttag ataagaatct gacacaagca cttgaagcac agcatggtca atttgaacta
    32101 tttgatttaa gtaagatggt tttctttaca tctatttgcg agtgggcagg tatcaattta
    32161 tcagcgattt ctaaagatga ggtcgaaaaa ttagcagaat atcaaatctc tatgatcagc
    32221 ggaacgttta cttctccgat tgatcacata aaaggtgtcg aaaatcgcaa aaaatcagaa
    32281 aaatgggcgc aaggcttgat tgaagaagct cgacaaaatc ctgtggctgg aaaagaaaat
    32341 gtggcattat atgcttttgc caatgccaca gatttagatg gtcagctttt acctctggaa
    32401 gtggcagctg ttgaattatt gaacatcatc cgtccaacgg ttgctctaac tgtgtgggcg
    32461 gcattgatgg gacatgcact tttcagtaga ccagatttgt atcagcaatt aaaaaatgac
    32521 ttttcgacgt tacaagatcc gtttattcaa gaaatgagac gctattatcc tttcttccca
    32581 atgctacctg cgatttcgct gaaagaagta gaagtagatg gttatcgtat accagaaggc
    32641 agttgggtta ttttagattt atatggaaca gaccatgatg aacgaacagt tgaagcgcca
    32701 gattccttta tgatcaaacg gtatgtaggg aaagcaaaag atatttccta taaagaagaa
    32761 tatgagatga ttgcacaagg cgggggaaat tttcgacaaa tgcatcgctg tgcaggagaa
    32821 tggatcactc ttcatagtct acgtgtgttt tccgatcagc tagtaaataa gtttgagttc
    32881 tctgtacctg aacaagattg gacgattcca ttcaatcagt ttccgactta tccgaatagc
    32941 cgagcgctac tttacaagaa ttagattagc ataaacttat cgaaaaaaag gaagatcaaa
    33001 cagtgctgat cttccttttt tcatattact ataaattgat aaggtcaatt gatcaaaatc
    33061 cacgaaatgc ttcatcaatg gtttgataat cttcattgga taaatgcaaa tctaaagctt
    33121 ggacattgtc agatacttgc tctggacgct tagctccagg tataactaca gacactcgtg
    33181 gattcttcat gtaccaagct aaaacaagtt gcgcaggagt ggcttggtat cttttagcaa
    33241 tggggcgaag tacatcgaca gcggttaaaa tttctctgaa acgttctcct tggaaatctg
    33301 gatttctttt tcgaggatct ccttcaccaa attgtttttc ctcaccaagt tcatattttc
    33361 ctgtcagcaa accggaagca agaggaaaat agggaacaaa actgattttg tttttttcaa
    33421 gataagggaa taattctttt tcagcctgcc gatggatcaa actgtattta tcttctacta
    33481 catcgacata tccatctgca ttcgcttctt tcaattgttc taacgtgaag tttgacacac
    33541 cgactgctcg gatttttcct gcttctttta attcgtgcaa tgtagcaact gattcatttt
    33601 ttggtgtgct ttcatccgga aagtggatat aaaaaatgtc gatgtaatca gtttgcagac
    33661 gttttagtgc atcttccacc gattgtttga gaaactcagg agaattatca aatgttcgcc
    33721 ctttatttgg tacatgagca gcttttgtag cgatgacgac acgtgagcga tcatattctt
    33781 tttccttcag tacctcgcca atcagttctt cggaacggcc gtttccgtaa gcataagcgg
    33841 tatcgatcaa attgatcccg ctattcaaag ctgtacgaac tacttgtttt cctgtctcat
    33901 cttccaaacc gtcaaaaaga ttatgtcctc caacggcatt tgctcctaat ccaagctgtt
    33961 ctgcgtagac ttgtgaatgt ccgattctta tttctgccat agctgattcc tcctttttgt
    34021 ctagtctaaa acaaaatacc aaaaagctga actaaaacgt ttttgtgagg ggaaatagtc
    34081 agatatctct tgactttgag actggttttt agtaggttat aagtaatatc gaatgtcaat
    34141 gaaagagcga gtaagttttt gaaactttac aagagaggat catcgaggct gaaaatgatc
    34201 taaagtttca ttagcctaaa gacactctgg agatggacga gtgaaaagcc gtcccgcgta
    34261 cgagcgttat tcgtaagagg aaagagaaat ctttcaaaat taggtggtac cgtgtatgaa
    34321 tttcattcac ccttgttcat gatgaacaag ggtgattttt ttatttacat agctaagaaa
    34381 gggagagaaa actatgagtt tccaaagacc aaaaggaaca aatgatattt tgccaggcga
    34441 atcagaaaaa tggcagtttg tcgaagaaac agcacgttta ttattcagag attatcagta
    34501 taatgaaatg cgtacaccga tttttgaaca ctatgaagtg atatcccgaa gtgtagggga
    34561 tacaacggat atcgtttcaa aagagatgta tgatttttat gacaaagggg aacgccatgt
    34621 gacgcttcga ccagaaggta cagcaccaat cgttcgttct tttgttgagc ataaattgtt
    34681 cggcccagag tatgcgaaac cgttcaaaac tttttatatg ggaccaatgt ttcgctacga
    34741 acgccctcaa aaaggacggt tacgtcaatt ccatcaaatc ggagtagaag catttggatc
    34801 agaaaaccct gcaactgatg tggagagcat ggtgatggca cttgatttct tcaaacagtt
    34861 ggggatcacg caaatccggc tagtcatcaa ttcattaggt gataaagaaa cgcgtcaagc
    34921 ctatcgtcaa gcattgatcg actatctttt accttttgaa tcagagctga gtgaagactc
    34981 taaacgccgc cttcatgaaa atccattacg cgtattggac agtaaagaca aacgagatca
    35041 aaaatttgtg gcagaagctc catctatctt agattatcta agcgagcctg ctcaaaaaca
    35101 ttttgatacc gttgtttcca tgctggatgc attggctgtt ccttatgaaa tcgacagtaa
    35161 tatggttcgc ggactagatt attacacaca tacgattttt gaaatcatga gtgacgcacc
    35221 aaaaatgggg gcacaagcaa cgatttgcgc aggcggacgt tatgacaatc tagtggaaga
    35281 actaggtggt ccttcaacac ctggcttcgg atttgcaatg ggtatcgagc gattactctt
    35341 gactatggag gcagaggaag tagttatccc tgcatttaat gagttggatg cttacgtggt
    35401 cgcactcgga gacgaaacaa atatcgaagc attgaaagtg gtccaagcga ttcgaaactt
    35461 tggtttttca gctgaccgcg acttcatgaa ccgtaaagca aaagcgcaat ttaagacagc
    35521 agataaagcg aatgccaaat tagtattggt gatcggtgaa gatgagcttg ctagtcaaac
    35581 gattaatgtc aaagcaatgg caagccgaaa agaaaaaagt tttccattag aagagatata
    35641 tgaacatttt gatgaagtct atgatgaaat gactttattc gagtaggagg aaaaaaataa
    35701 atggcacaaa gaacgatcta ttgcggatta gtttccgaac aacaattaga acaaacagtt
    35761 acattaaaag gatgggtaca aaaaagacga gaccttgggg gagtaatctt tatcgaccta
    35821 cgtgatcgtg aaggaatcgt tcaaatcgtc tttaatcctg aaatcaacaa agaagcatgg
    35881 gaaatcgcgg ataaatgtcg cagtgaatac gtgatcgaag tgactgggga agttagaaga
    35941 cgcggagaaa atgcagtaaa tcctaaaatg gccactggtg aattcgaagt gattgcaagt
    36001 gaaatcgtga ttttgaatca agcaaaaacc ccgccatttc aaattgaaga tgatcaagca
    36061 atcagtgacg aaatacgttt gaaatatcgt tatttggatc tgcgtcgtcc aaaaatgact
    36121 aaaaacatca aattaagaaa tgcgacaaca aaagcgattc gtcattattt agatgataat
    36181 gactttctcg atatcgaaac accttaccta ggaaaatcta caccagaagg cgcaagagac
    36241 tacctagttc cttcacgtgt ccatgctgga catttctatg cgttgccgca atctcctcaa
    36301 ttgtttaaac aattgctgat gaatgctgga ttcgaccgtt attatcaaat cgttcgttgt
    36361 ttccgcgatg aagatttacg tggagaccgt cagcctgaat ttacgcaagt agatattgaa
    36421 acaacgttct taacagcaga agaaatccaa acttacacag agggattgat tgcgaaggta
    36481 atgaaagaag ttcgcggtat cgaagtcaca ttgccatttc ctcgtatgac ctatgatgaa
    36541 gcaatggctc gctacggcag cgacaaaccg gatacacgtt ttgatatgga attgatcgat
    36601 ctaagcgata cagtcaaaga agtagaattc aaagtcttcc aaatggctct tgaaaacggc
    36661 ggtgtcgtga aagcattgaa tgctaaaggc gctgcagatc gctactcacg aaaagacatg
    36721 gatcagttag gtcaatatgt aggacaattc ggagctaagg ggcttgcatg gctgaaagta
    36781 gaagaagacg gattgaaagg tccaattgct aaattcatgg gagaagcaac agaagcaatc
    36841 attaaagcaa cagatgcaaa accaggtgac ttgctgatgt ttggcgcaga taaaagtgaa
    36901 atcgtcgctg ctgcattagg tgctatccgg acacgtttag gaaaagaatt aggactaatt
    36961 gatgaatcga aattcaattt cttatgggta actgattggc cacaatttga attttcagaa
    37021 gaagaaggtc gatatgtctc tgctcaccat ccattcacga tgccaaaaga agaagatatc
    37081 ccgttattgg ctgaagaccc tgcaaaagtc tatgcagaag cttatgatat cgtcttgaac
    37141 ggttatgaac taggcggagg ttctatccgt attcatactc gtgagcttca agaaaaagta
    37201 ctagaaactc taggctttac aaaagaacaa atggaagaac aatttggttt cttgttaaca
    37261 gctttagatt acggattccc tccacatggc ggtattgcat taggattgga ccgttttgca
    37321 atgttattag ccggagaaga taatattcgt gaagtcattg cctttcctaa aaacggaaaa
    37381 gcagcagatg tgatgagtga tgcaccaagt atggtttcgc ctttacaatt gttcgaattg
    37441 aatattgatg taacgaatat agaagaatag ccgataaaaa ggtaaaaagg atttgtcgaa
    37501 tacgcttctt ttgacaacct tgatttaatt gaaaaacact ttataatgaa gccataacat
    37561 ataaagcggg gcttttccat gaaaaaaaca ttcgaaaatt gggcttatca tgattacacg
    37621 accaagcttt cggtatctat cgtttatgcg ttgatcgcat cagtcgcatt gaatttcttt
    37681 tatcagccag gacatattta ttcaagtggt attactggtc tagctcagat tttgacgact
    37741 ttgtcaaaat cactgatagg attcgaagta ccggtatcaa caactttgta tttactgaat
    37801 atacctttgt ttgtattggc gtggttaaaa atcgggaaga agtttacaat tttcactttt
    37861 atcacagtca ctttgacctc cctttgtatc catattttac cggaaacagt cctatctacc
    37921 gatccaatca tctgtgcgtt gtttgggggg gctgtgatgg gactaggtat tgggctagcg
    37981 ttgagaaacg gcctatcatc gggcggtcta gatatcgtga gtatcacgat tcgtaaaaaa
    38041 acaggaaagt cgattggttc tatttcgatc tacttcaatg cattgatcgt ttttgttgcc
    38101 ggaattctat ttggctggca atatatgttt tacagtacgt tgtctatttt cgtcagtgga
    38161 aaagtaactg atgtcgttta tactaaacaa aagaagatgc aggtaatgat cgtaacgaaa
    38221 catccagaaa aagtagtaaa tgaaatccaa aactgtatgc gtagagggat cacgatcatc
    38281 aatgaagcag aaggtgctta taagcatgat aagcagacag tattgatgac gatcgttaca
    38341 cgatacgaac tgcctctact tagagaagca atgaaagctt ctgatccaca agcttttgta
    38401 agtattgcag aaaacgtcca gatacttggt cgtttctatg aggatggcat ttagatcgag
    38461 tttgacaaaa attcatgaaa tactgctgta gacagacgtt cgtttgtctg cagttttttt
    38521 ctaccatagt agaatcagca aagaaaaact gcttttttat ttgaaatttt cttaaagttg
    38581 aaaaaaagca tgtttatttt tttaaattta tgggatgata gaaaaaaata gtagagaaag
    38641 gacacgattc tacttgctat tttcacttaa tacccgtata ttacgaatga aaaaagttta
    38701 tgaaaagttg gaatattgaa tggaaaaaca aaaaaggtta aaaaacagcc gctacatcac
    38761 tgggtttgat gggctccgtt cattagctgt ggtgggtgtt atcttctatc accttctgcc
    38821 aactagtatg aaaggcggct atttgggcgt tccgattttt ttcgtcgtat ctggttattt
    38881 gatcacggat ctgctgcggc aggaatggga acaaaatgga aaaatcaata tttggcaatt
    38941 ttatgtcaga agaatgaaga gactctatcc ggcacttgtt tttatgcttg tgacagcttc
    39001 ggcttatatc actttgtttc agcgagggct gttaaacaat cttcgaggag ttgtggtcag
    39061 cagcttactg tatgtcaaca actggtggca aatcaataac ggtttatctt atttcgatcg
    39121 atttgctaat gagtcaccgt ttacgcatat ctggtcttta gcagtagaag gtcaaaacta
    39181 tttggtttgg ccgatcttgt ttgtattgtt gatggtattt gttcgtaaaa gaaaatggat
    39241 cttttatact gtgttaggta catccttcct ctccgccatc ttgatgatga tcttgtatac
    39301 accaggaggc gatccaaccc gtgtttatta cggtaccgac actcgtctgt tttctatatg
    39361 gttgggaagt gcgcttgcgt ttgtttggcc aagtacgcgt ttaaagaaaa acatcccgaa
    39421 acaagcgaaa aatattctga atatcgctgg aggaatctcg cttttggcac tgattctttg
    39481 cttcttcttt ttagatgatc attacaattt catctattac ggaggaatgc tcctagtgag
    39541 tctgttatgc gtagtgctag ttgcagtgac agcacacccc ggagcaagtt tgaatcgatg
    39601 gctgacaaat ccagtattta cttggattgg caaacgaagc tatggcattt atctgtatca
    39661 gtttccagtt atgatttttt atgaagcaaa ggtgactgat attgccgatc atgttttgtt
    39721 gcatacttta gtggaaatca cattgattct aatcatcagt gaactttctt atcgatatgt
    39781 ggagcgtccg ctagcacgtt ttgattatgg tcgtacattc caagtgatga aaggatggtt
    39841 cagcaaaccg atcatcagta agagcaaacc atgggttgtt ccaggcacat tacttgtagc
    39901 aattgcactc gttggtttcg ttacggcacc gaaaaacgct gtaacagccg atcaaaaaca
    39961 actgcaggca aaaatcgctg aaagtaaaaa attagcagaa gaaaccagaa acaattcaga
    40021 aaacaccact agttcggttg accaagcgat ccttgataag tacgagttgt ccaaggcaca
    40081 agggaataag gcacaaaaat tagaactaac ggcatttggt gattcagtta tgttggatgc
    40141 tgcaacggat ctacaagaac tttatccaaa agtagtggta gatggagatg tcggacgaca
    40201 attatatgcc agtgtaccgt acattgaaaa attaaaggaa caagatttgt tgaaagacac
    40261 tgttctgatc ggactaggaa cgaatggctc attctcggaa gctcagtttg atagtgtgat
    40321 ggatgcaatc ggtgatcgaa aagtatactg ggtcaatgtc cgagtaccga cgaagcgctg
    40381 gcaaaatgac gtgaatgcga tgcttgaaca gatgacgaaa aaatacgaca atatgacgct
    40441 gattgattgg tacagctaca gtaatgacca tagtgactgg ttttatgatg atcaagtcca
    40501 tccaaatcct gaagggatga cacattacat tcacttagtc agcgaagcct tgctaggagg
    40561 aagttcaagt acgaacagca gtgagacaaa cgtgacagaa tgatagctac aaaaaacttc
    40621 aggcaaaaac atttgttttt gcctgaagtt tttttatatt taccgtgttt ttaacattca
    40681 tatagattca ggaagcaaaa cggttgagtg tgtctgtaaa taacgttctt tttgttttcg
    40741 ggtgagtttt ttgaatgcag cttctgcttt tgttgcttcg cttcttgaag aaaatacttc
    40801 tgcatggatc atcttaacag gtcttctttt ttgaagacga gtatatttag caccagtacc
    40861 attgttatgt tcctctaatc gtctagaaag atcggttgta tatccaccat aaaatgtctg
    40921 atctttacag aataatacgt aaaaataatg ttcatttgcc atagagcatc tcacgaatct
    40981 ctgcagtgta ttctccatcc atattgtaag tgatcaatgg tggagcgact ttgaatccgt
    41041 ctaatttgcc ttctttgatt ccttcaacta acaaaatatt tgcctctttt ccaggttttg
    41101 ggtaaacaaa ttggatcctt ttaggtgcaa ttcgatagtc ttccatgacc tgaatgattt
    41161 ctaagaaccg atcaggacga tggaccatag taaagcgtcc atttgttttt agtagcttac
    41221 ttgaaatatc gatcacttct tctaacgtcg tatgaatctc atgacgggcg attgccaggt
    41281 gtttattagg gttcgtttta tttgttggca gccctttgaa ataaggtgga ttacagacga
    41341 ctaagtcaca agaattatgt cgaacgacag ataagctgtc tttcagatcg atggtgtgga
    41401 cagtcatttg ttcatttaaa tggttaagcg cgatactacg tcttgccatg tctgctagac
    41461 gaggttgaag ttcgatagcg tcgatagccg cctgggttcg tttacttaaa aaaagtccaa
    41521 ctgcgccatt tcctgcacaa aggtcaacaa tcttcccttt tttaggtaca cgggaaaagt
    41581 gagcaagcag cacagcatct aaagaaaaag aaaacacttt ggaactttgg ataatcttga
    41641 tatcttctgc gtataattgg tcgattcgtt cgtcttcgtg aagcatggat tccctccaaa
    41701 atgaaaaaaa tagtcgtctg tattatacta tttttattaa aaagaaccaa ggtggcttgt
    41761 caaacctcta ttttttatgc atactatgac cataagaagg gaaaggaaga gactatgttt
    41821 tatcgattta tgcgcggggt agttcgagta ctattagcct tagttaatgg aaatgcccgc
    41881 tatgagaata aagaagtttt accgcaagat gagaattaca tactagttgc tccccatcgt
    41941 acttggtggg acccattata tctggcggta gctgcagcac ccaaggaatt cagctttatg
    42001 gcaaaagaag aactgttcaa aaatccagtt ctgcgattta tattaactcg atccaatgct
    42061 tttccagtta aaagagaaaa tccaggacca agcgtcatta aaacacctgt aaagattttg
    42121 aaatcgacaa atttgagttt gatcatgttt cccagtggga caagacatgc tacagaactt
    42181 aaaggcggaa tggcattgat ttccagaatg tctaaagcga aaatcgtgcc agctgtatat
    42241 caaggtccgt tgacacttgg ggatctgttc aagcgtcaga gagtgacagt gcgtttcggc
    42301 gaaccaatcg acttatcaga tatcaagaaa acggataaag aaggtatggc ggagatcgaa
    42361 cgacgaacac aagcagcttt tgacaaattg gacaaagaag tgaaccctga tttcaaatat
    42421 gaagtcaaaa aaaaataaaa tgataagttt atgcgtgggc ggtcttttga atctactgtc
    42481 ctgttcagtt cagacttttt caatgaaaac gagggagaga cgtcaagtct gccctctttt
    42541 tgcgttccaa tatgtaaaat agaagacagg tgtcatgtaa tggatcaaag tgttataata
    42601 attagaagga cattttttga ggtgattgaa tgcgtttttt acatacagcc gattggcata
    42661 tcggaaaaaa actacaaggt tatgacttga ttgaagacca gcgtcatgta ctatcttcta
    42721 tactagatat cgcgaaagaa gaaaaagtag aggcaatcgt gattgccgga gacttatatg
    42781 ataggagtgt cccagctgtt gatgccgtag aattatacaa tgaattgatg gtcgattgga
    42841 atttaaagga aaagatcccg atttttgcta tatcaggaaa tcacgatagc agtacgagac
    42901 tttcagcggg tacgccatgg ttcagttatt cgaactattt tttgcgaaca cagctagcag
    42961 aagcatttga accagtcgag tttaaaaacg tacaattttt ctttcttcct tactttgaac
    43021 caattgcagc gagattatat tttgaagatg acaatatccg aacgatcaag caagcggtag
    43081 ccaaggtgat agataaaatg caggagctat ttgattcaga aaaaaaacaa gtattgatta
    43141 gccatttttt tgtaatggga agtgtaaaat ctgattcgga aacgaaaatc gaagtaggcg
    43201 ggttggattc gatccctggt gaactactta caccgtttga ttatgtagca ctaggacatt
    43261 tgcataatca agctgctttg agacaggata atgctcgcta tagcggttcc ccattgaaat
    43321 tctctttatc tgagatcaac caaaaaaaag gcgtatggat cgttgacctg acaacaggcc
    43381 tggagttgaa ttttagggag atcgaacccc tgcatgatat tgaagaaata acagcgagtt
    43441 tcaaagaatt gctggatcct gccttttatc agtccgtcaa tcgggagaat tacatctata
    43501 tctatctcac tgatagaacg atcatcccga atatgatgaa ccagcttcgg caaatatatc
    43561 ctcgtatttt ggggattgaa cgggcaaacg gtcgagcaga acaaacaaag cgcaaacgaa
    43621 aagtactaga aatgaaagat cctcaaaaat tagcagaagc attttttagt gaaatgacgg
    43681 aagagcagct aactgcaaac caagaaaaat ggctcggaga aacgttgcaa gaaatcatgg
    43741 aaatggaatg atcaagaatg aaaccgaaaa aattacaact taaaaatttt ggtcctttta
    43801 tcaatgagac cgtagatttt tcacgtttga cagaagcacc gctttttttg atcagcggga
    43861 agacaggagc tggcaaaacg acgatttttg atgggatcac cttcgcactt tttggtgaaa
    43921 cttccggaag acttcgctct ggaaaagaga tgcgttcttt gtttgctaca ccagacgaag
    43981 aaacaagcgt gactttttct tttgaacatc agcagatgag ctatgaaatc gaacgaaaac
    44041 cagaacaagt tttagcaaaa cgaaaaggaa acggaacaaa aaaacaggca gccaaagtaa
    44101 cgttgaccat ttttgatggg aaaggaaaag aaataaaaca aatcacaaaa cgtacagaag
    44161 cagatcagtt gatcagagaa ctgatgaatc tcgatgcgaa acagttttct caaatcgttt
    44221 tactacccca aggagaattc cgtaattttt tggtttcatc aagcagtgat aaagagactg
    44281 ttttacgtca tttattcggt actcaatttt tccaacagtt caatgagcga ttaaaagaaa
    44341 aagcaaaaca acagcaacaa aaattggatc atttagagca agagctgcat cttctgcaaa
    44401 aaaggtttgt tttagtcaaa gaagaggaac cagcagcagg gtttgaagcc gttttagccc
    44461 aatggacaaa ccatcaggca atactcgaaa aacaaatcac ggaagaaaaa gaagctctaa
    44521 cggaacttca ggaaaaacaa aagcaactag aaaattccta ctatcgtttt gaaagcttga
    44581 aaaaaagtta tgaagaaaaa acgatattaa taaacaagca aaaggaatta gctgctcaaa
    44641 aagacgaaat agaggaaaag aaacgatgga ttgggtatta tgaatttacg caacgattag
    44701 tcgaaccaat ccagcgccta caagaaataa aagttgaaaa aatagaactg tcacaaaaaa
    44761 gtagtgagca aacaaagaaa ctagcgatga ctacgcagaa ttatgaagag tggcaaaaaa
    44821 atgaagcaaa ccgcgtacgc cgacaaacaa aaatcaaaga agctgctcaa aaactgcaaa
    44881 acaaacagat gatggtgcca attgtcgaat ccttacgtag taaaaaacaa gacgcagaac
    44941 aattaacaat ttcattggat aaagaagaat tgaatgccga gaagctgtat caaaatctcg
    45001 ctatctatca ggaaagaact cgaattcttc aagaaaattt actggatcag gaaaaactgc
    45061 aagaagatcg tcttgctttt ggacagttaa aatatctaga tgaaaagcag caagaaatag
    45121 aaaaacaaaa agcaaaagac actgggtcgc tcgcacagat aagagaagaa ctcaaaaaag
    45181 caactgaaga aataacaaaa aatagtcagc tattgaaaga acagacagaa caagcagaac
    45241 agctgaaaag ccaatgggca aagcagcaaa ttgctcgtct tcagcttttt ttgcgtccag
    45301 gggagccatg tcttgtttgt ggatcaacgg aacaccccat acaacaatta aaacacgaac
    45361 agccaaataa ggaagatatc ttaaaagtag aacaacaact ggcagaagct gagtctgctg
    45421 tagaaagaac tcagcaaatc attgccaaaa gtgaagcaca tgaaaataat cttcaacaac
    45481 aattatcaga tttagaacaa aaaatcatgg caacgaatat acaattggct gaacaagaag
    45541 aacacttgca acaggctttg aaaaaggcat ttcctgagat aacagaacaa aaaacaaaaa
    45601 caactcttgt agtaatcgaa caatctttag atagacgaaa aagcaagatg gccaatgcaa
    45661 gaatagagct ggaagaaata agacaacaag cagaaaagct cgaacaacaa ttagctgtct
    45721 acaaacagca gcagacagaa aaaaataatc agctccagca actgcaagga gaaatcaaaa
    45781 gtttagaaca acaattgcaa gatacggata gtaactgttt agaagaggag atacgacgac
    45841 ttgaaaaaca gttagaagaa gactcgaatc aactagctgt tgagcagaaa gcaggagtgc
    45901 aattgttgca agatcttcat acgcttcgga cacagcttga tcttcaacat gaacaaatag
    45961 aaaaaataga tgaaaaaata gaaaaggaac aagaaagaat agctaaaaag ttagaaagcc
    46021 agtcgtattt ttcaacaatt gaagaaatct gtgcatttgc acaacagcaa gcacaatata
    46081 aagaaaacca acgtacagtt acttcttatc atgaagagca attagtgaca gctgaccggc
    46141 tgcgtcaatt agaaaatatc cagctaactg agacattccc agatacagaa gagatcagcc
    46201 aacagttaga agaaataaga cgtatgatcg aaataaagca agaaaagata tacggtttac
    46261 aagaacaaaa aattagtaat caaaaaatct acgatgaatg tctttcgatt tatcacacaa
    46321 gccagacgaa attagatgag cttacgcaat tacagcagct ttcgcaaaca ttcaacggag
    46381 aaaatcctaa gaagactagt ttggaacggt atgtgcttca ggtttatctt caagaagtgt
    46441 tacaagtagc aaatgatcat ctccaacgtt taacgaaaaa tcgttatcaa tttgagctag
    46501 cggataccat tggcagttat cgagggaaaa ccggattaga aatcaatatc tatgatgatc
    46561 aggcaggtat gtctcgaagt gcgcataccc tgtctggcgg tgagagtttt attgcagcac
    46621 tttctttagc attagctctt gccgatgtga tccagacaca agctggtggt gtagcaatcg
    46681 atgcattgtt tattgatgaa ggatttgggt cattagatga agaagctttg gaaatggcaa
    46741 tggaagcttt agaaacgatc gaaagtgaag gaagaatgat cggcatcatt agtcatgtaa
    46801 gagaattgaa agaacgagta ttacaacaaa taagaattga tacagaaggt agcggacaaa
    46861 gcaaaatacg ctatcaactt ggataaaaag ggagattggt aactatgaaa tggagtattc
    46921 cagaaaaagt cattgcacgt ggacgtcaat acttgcaaga aggccgagtg ttatcggttg
    46981 tccctgacca agaagaaaac gtgtggcatg cagaagtctt gggcagtgaa ttgtatatgg
    47041 ttgatttgga tggtacagca aaagagatag attactgcca atgtccctat tgggaggaac
    47101 ataaatattg taagcataca gttgctgtgg aactttattt acggtcgaaa aatctatctc
    47161 gtatcatgaa aaaagaccag ccaatgctag aaccggtaaa agcaacaagt gagggagaaa
    47221 tcattgcaaa aggtttttct cgtctaaaaa cacaaaacaa tcctcaagcg gtgcaacctt
    47281 tgattattga ataccaagta gaaacgattg agactaatca gtatcaccca gagctttcta
    47341 ttttggcact ttacttgcgt atcggttcat tggcatcacc gaaaaaaaca tatatcgtaa
    47401 aaaacatcta tgatttttta caagcttaca cagaaaaaga aacttacact gttaataaac
    47461 agtaccagtt tcgtctagat aaacgggcgt ttcaaaaaga agatcaaaaa atactcacgc
    47521 atcttgcagg aagtgctcag acgcatcaat tattaggtac gaacggctta caagtcaaag
    47581 gaaaactaga taaaagatat ctgcttctcc cagtagaaca agcccgcttc ctgttagagc
    47641 agatgaatca gactacacgt ttgcatctgc agataaatga acaaaacgat caaggaatac
    47701 aattttccga tcaaaacaaa cctttatcat tcaaagtgga aaaatttgga gaagattatt
    47761 tgctgcaagc attgaatgat tttgattttt tctttatgca ttatcagtgg ggagttatcc
    47821 aagggacatt ttattctctg acgaaatatc aacaaacggt ttatcaaact tggaaacaat
    47881 tgattcgccg attggagaaa ccagaagtag tgttcaagaa aaaagaatta ccgtctttgt
    47941 ttaaagagat tatccctctg ctgtcagaga tcggcgacgt agctattgcc cctgcagtag
    48001 aagaggaagt agcagatatc cccgtcgaat ttattttctt tttccgaaaa gcaaaaggaa
    48061 aaatccaagc tcgagtcgat ttcgtctatg gcgaagtcat ctattcgact gacccgaagc
    48121 atgaggtctc gacagaacag gcttttcagg tgttacgtga cacagtagaa gagaaacgag
    48181 tacttgatct attcagaatg tatcgctacc agaaaaatga aactggttat gaacgtccat
    48241 tgccaagcgg ggaagaacta tatgcctttt tccgcacaga actatctgtc ttccgtcagt
    48301 ttggtgaagt cagacttgga agaaaattgc gagagttgta tttagatgcg cataaacatc
    48361 aaccgaaaat cgaagtaacc gagaccggtt catggctcga tattcgattc gatgtgacag
    48421 ggatagagga gcaagaaatc gatcatgtcc tgcaaagctt gctgagaaat gatgcttttt
    48481 atacattaga aaatggtcag gttctttctt ttgattcaga agaatttcaa caaacaagcc
    48541 aagtgttgca acaattacgg gaatcgatac gtacagaaga aggaacgatc catgtaccta
    48601 aaaatcaagg attgatcatt caaaatcaat tggaaaaaag caatgctact tttagtgaat
    48661 cgttccaaac gatggtacaa gatctcattc atccagaaag ataccaggca cagcttccca
    48721 aaggattgaa tgcaacgatg agagattatc aaaagcaagg ttttcgatgg ttgaagatgt
    48781 taggtcatta tcagtttggc ggtattttag ccgatgaaat gggacttggg aaaacactac
    48841 agacaattgc ctttttactt tcggaaaaag aagaacggaa aagcttctct gctttgatcg
    48901 tagcgcctgc gagcttaatt tacaactggc aggcagaggt gagaaaattc gccccttctt
    48961 taagtatcca agtaatcaat gggaataaaa aagaacgtga agaattactg gctaaagaca
    49021 cagatatccg agtgacttct tatgccagct taagacagga tctagctaat tatcagtcgc
    49081 aaaaaattga ttatttgatt cttgatgagg cacaaatggt caaaaatagc agtacgaaaa
    49141 ctgcacaagc attgagagaa ttagctgtac ctcagcggtt tgcactgagt gggacaccaa
    49201 tcgagaataa tttagaagaa ttgtggtcat tgtttgcaac gattatgcca ggatttttcc
    49261 cgactaaaac aaaattcagg gaacttgccg cagaagaaat tgcgcaaatg attcgaccgt
    49321 ttattttacg gcgagataaa caaactgtgt tgaaagactt gccggaaaaa acagagatga
    49381 atctatattc tgcacttaca gaagaacaaa aaactgttta tttagcttac ttgcgtcaaa
    49441 tgcgtgaaga aatcacatca atggattctg aagcattcaa gaaaaaccgg atcgggatac
    49501 ttgctggtct gacaagactg cgacaaattt gctgcgatcc tcgtctgttt attgaagatt
    49561 accaaggcgg ttccggcaag ctcgaacaag taaaagatct actggtagct gccaaagaga
    49621 acaaacgaag agttttgctg ttttctcaat ttacagggat gctgactatc ttgcaagaag
    49681 agttagccga gctagggatc tcgacatttt atttaagagg cagtacgaaa ccacaagatc
    49741 ggttaagtat ggtagacgca tttaatgctg gcgaaaaaga tgtttttctg atttccttaa
    49801 aggctggggg aactggattg aatctcacgg gagcagatac ggtcatcttg tatgaccttt
    49861 ggtggaatcc tgccattgaa gaacaagctg ctggacgtgc acatcggatc ggacaaaaaa
    49921 atgtggtaga agtgtggcgt atgatctctg aaggaacgat tgaggaacgc atggattcac
    49981 tccagcaaga aaaacgcgaa ctgttccaaa aagtgatcca aggtaatgaa gaacagttga
    50041 cgaaactgac tgaagaagac atccgcatga ttttaagtgt aggagaaatc gaggagtaag
    50101 agactcgaaa aagcgttcag taatgggtaa gaaagccttt ctaaagaagc gattgtttat
    50161 ttgatttaaa aaatagcaag gaggctggga ttccatttta tcccagcttc cttgctatca
    50221 tttttttatt tctattttta aaggttatac aaagattgtc ttcattgtct ctaacagctg
    50281 atcaaaagaa gaaatctcga tatcgcaaat tggagtctgt tcaattttgc gttctcgatg
    50341 gttgaaccaa agcgcttgcc agttagcact ttttgcacct agaacatcat tgtcgtaatt
    50401 atcgccaacg tataaggtct cttctggaag catatgaaat tctttctcag ctagctgaaa
    50461 aatctctttt tctggttttt ggaaacctgt tgcttgagaa atgagcatat tgcgggaagg
    50521 aatccaattg ttcaattgaa gttgcttcag tttttttgtc tgatggtcag tcggcccatt
    50581 tgtgataatt cctaatggga cattcttttc cttcaagaaa tcgagggttt ttttgacctc
    50641 ctcatgcaag cagatattat caagttcttc ctcgtaaatt ttttgaaata agaggccatc
    50701 ttcttccgta atatgagggt agtctaaatc ttttagtgat tggctgatcc gatgtgctcg
    50761 catatattct agtgtccaat ctcctgccat tacttttggg aagttttcat cactatgatg
    50821 gcggaaccgg atatatagtg gatgcatatc tgcatctgaa acaagcggaa cgactctttt
    50881 gaccgcgttt cgaaatggct gctgctgatc atacatcgta tcatcaacat caaacacaac
    50941 tgatttaatc aaaattttac acgcctttcg gttttcattg attttttcac aaatccttga
    51001 ctattgtaac agaaaaaatt gtctaaaaaa gctgataaat aaaggttttt cttactatat
    51061 ttctatttcc ttgacagaat aaggttttta tatttcagtt tttttcacta aaaatcgtga
    51121 aacacgtcaa taagtttgat gaacaaatta atcattatgg tagaagtcga ttgatttatt
    51181 ttaatgcaat ctctgtggaa ttttcgaaag atttattttt ttaatacagt ctcaatataa
    51241 ctattcaaac ataaaataac gttatttgat ttatttgttt atagtaaatt ttatttagta
    51301 atcattgctt taaaatacta cgcttatata acagagaaaa taagcgttat aataaagaac
    51361 agtattattt aaaatgacag aaaacattac tattaaagaa ataaaaaaca taaaaaatct
    51421 taagaaatcg gtttcattta gcttttgaga taaaataata gtacagtttt atacgctgtt
    51481 tcatatgttt agaaaatttg aattagattt gaaaactcta atttttaaat gataaaaaaa
    51541 gcgagaatgc tggttttact gtatattaac cttagataac tttcattttt ttaaaaaaat
    51601 tatgaaaaaa aggtagctat ttaaaagttg attatgtata atagaaacag atgggagatt
    51661 attatgatct tctgttacaa aaaagtgatt cttatcacga aaaggagtgg tgcacgttgt
    51721 taacattata tacttcccca agttgtactt cctgcagaaa ggctcgtgcg tggttgcaag
    51781 aacatcagat tccatttgtt gaacgtaata ttttttcaga accattgaac agttctgaat
    51841 taaaagcgat tttacaaatg acagaagacg gaacagaaga aatcatctcg acacgttcca
    51901 aagtattcca aaaactgaac atggatttag atgatctgcc gttacaagaa ttattggaac
    51961 ttgtgcaaaa caatcctgga ttgcttcgcc gtccaatcat gattgatgat aaacgtctgc
    52021 aagttggttt taatgaagat gaaattcgtc ggttcctacc gcgcgatgta cgacaattag
    52081 aattacgtca agcacaattg atggctggat tatagaagga taatacgaaa cttggaaaag
    52141 actattacaa agatagtttt tccaagtttt tttgttttta caaaaagtat tcttgattag
    52201 atgtataaaa aggtagtaga agatgatgat tgcacgaaaa atagagaggg aaaattagct
    52261 gaaaagtcgg ctatatagta ttcgtctgcc aaaaatgtta tagttaaata agatagcttg
    52321 aaaggttgaa aaatccgctg gttttattaa attcgcttaa cagcgagatt ttttttcttt
    52381 acatttaagc tgatttcgct acaatgaatc tatattaaac attgtggcaa agtgaggtgt
    52441 agcaaaatgg aaatggaaca tattaatgaa aatacgatcc gtgtactaat tggtcatgaa
    52501 gatttagagg aacggggcgt ttcatttttg gatttacttg gcaatcacaa agaaatcgaa
    52561 aatttctttt atagtatttt ggaagaagtt gatatcgaag aggagttccg aggaagcgaa
    52621 gctgtcactt tccaagtttt gccaaaagga gacggattag aactgtttat cagtaaaaat
    52681 cttccggatg aagaaatttc tcaatcagaa gattctactg ttgattcaga agatgtgagt
    52741 gactttcttc gtcagcagat tattggcagc gatccggagg aagaattatc tggaagcgcc
    52801 ctagaagaac aggaaagaca agcaactttt gcttttgaag attttgaaca agtgatccaa
    52861 cttgcaacag atgtcgaact agagtctgct tggactgatt tgtatttatt cgaagagcgc
    52921 tattacctag tcgttcactt ctggatggaa aatctcaacc aagcggatgt agagaatcag
    52981 attgctcgaa ttttggagtt tgctgaaaag agcgatcgta caccagaaac attgaatgaa
    53041 tatggacaat gtctgatggc gcgtaatgct atcgagcgaa cgaaatttta ttttgtataa
    53101 atcagcatta tagtaagaga ctgtgacaaa aattgtgtcg cagtcttttt ttcgtataaa
    53161 tgtgttcaaa agcttgcatc tgcggtaaca agcccaacca aacgaaaaat attgggaact
    53221 atttttgttt agctgttctt attacttgat gcagaatagc tttttcacgc cctctttttt
    53281 cgtgtaaata aattcttaga cgtaaataag ttcagaggga gaaaaatgct gcttgcaatg
    53341 aatgaatata ataagtgctg ttttgctaaa catgcagaaa aaggaaagaa atattattgt
    53401 cgtggctgtc gaaaaagagt gattttgaaa aagggaaaga aaaaatgtgc tcattttgcc
    53461 catcaaaaat cagataactg ttcggtcttt agtgaaagag aatcaaaaga gcacttacag
    53521 ttaaaggaat gcttcatgga ttggctggga cagtcagtag aaccagtatt tttggaagcc
    53581 tatttgccga ggttgcggca aaggccggat attttgttgg cgaatctagc aatagaaatc
    53641 caatgttcta gactgtctca ccagagattt attgaaagaa cccaaaatta tttgaataac
    53701 agttaccaag tatggtggat acttggtaat tcttttcttg gacaatcgca attctcattg
    53761 atagaaaaaa gttgctgcta ctataataga aaaagaggag tgcattgctg gaaagctgat
    53821 ctcaagaaac aaaagcttta tttgtatcat catattacag agactgtatc agggcatatt
    53881 tccttttgca gtagctgctg gactttttct agtagggacc ttaaagaaat attcactagt
    53941 aacgaaatta aaatgaacca aatgaaaaaa atagaaaaag tgagtgaaga tgggaagaaa
    54001 tggctgacac gccaacttat tcacaagcaa aagaatacag tatccataca agaacaatgc
    54061 tacttgcgtc ataaacatct tttgcatcta tcatcgtgga tctatcaaaa aagtcggttt
    54121 ttcttttatt tacaagaaca ggtttttctt tatcgaatgt tgtacgaaga agccttggaa
    54181 aaccagaaag ttcctgattt caactcatgg ctttgccaaa taaaagaaca taaaagggaa
    54241 tggctttttc ctatgattga tgaagagatg gtctatcagc agttttttaa cgaatgcata
    54301 cacttgtctt ctttgaaaaa atagtaagta taaaaatagg ctaggaatcg gttttctatg
    54361 taaaacaaga tttagttatg ctaaaattga tggaagcaga cacatgaatg agtagaaaag
    54421 ttagatgctg tgacatgtgg atgttagact atgatctatt ttgatagata gagctaaggg
    54481 aagaaaagga gtggatttca tggaagtaaa gcagttgcca aaacgagaag aattgcctga
    54541 aaatttaact tgggacttga ccaagatctt ttcaagcgac caagagtttg atgagaaata
    54601 tttggaatta tcagaagagt taaaacaatc tgaaaaacac aaaggaacac ttgatcaagg
    54661 cgcttctcaa tttttaaatg cgattgaatt cgtattgagg gtttatcgcc aaactgaagt
    54721 catttatgta tatgcgcacc ttaaaaacga tcaagacact ggaaatacag attaccaagc
    54781 gctttatgca agagcaagca gtctgttttc gaaagttagt gaagccgttt cctggtttga
    54841 accagaaata ttgcaattgt cagatgacca gatttggcaa tatttcaaag aagaaccaaa
    54901 attggaagtc tatcgccatt atatccagca aatagtagat aatcgagccc atgtcttatc
    54961 tgctgagcag gaatctcttc ttgctggagc aggtgaaatc tttgatgctt caagtgatac
    55021 atttgctgtt ttgaataatg cagatctagt ttttccaacg attgaaggag aaaatggtga
    55081 aatagtccaa ttatctcatg gcgtgtatgg tcagttgcta gaaagcacgg atcgaagggt
    55141 gcgcgaagca gcatttaagg ggttgtacag tgtttacgaa caatttagaa atacatttgc
    55201 ttctacttta ggcacacata taaaaggaca taattttaaa gcgaaagtcc gtaattacag
    55261 ctctgccaga gaagcgtctt tgagcaataa tcatattcct gaaagtgtat acgatacttt
    55321 ggtagacgtg gtaaacaagc atttgccttt gttacatcga tacatggaat tacggaaacg
    55381 tttattagaa gtggaaaaac tgcacatgta tgatctttat acaccggtct taggggaagc
    55441 tccaattacc tttacgtacg aagaagcaaa agaaaaagct ttagaagcac tgaaaccaat
    55501 gggtgaagaa tacatggcca tcgtagaaaa agcattctct gaacgttgga tcgatgttgt
    55561 cgaaaataaa gggaaacgaa gcggtgctta ttcttcggga agctatgaca caaatccata
    55621 tattttattg aattggcatg atacgctgga tcagctattt acgcttgtcc acgaaatggg
    55681 acatagtgtt catagttatt tcactcgttc gaaccagcct tatgtgtacg gcgactactc
    55741 catcttttta gcagaaattg cttcgacaac gaatgaaaat atcctaacgg agtatttatt
    55801 ggaaacagaa aaagaccctc gtgtacgggc ttatgtactc aaccattact tggatgggtt
    55861 taaaggaaca gttttccgcc agacacaatt cgctgaattc gagcatttca tgcatacgga
    55921 agatgaaaaa ggtgtgccat tgactagtga atacctaagt gatagttatg gtaaattgaa
    55981 tgcaaaatat tatggtccag cagtcgaaga agacccagaa attaaattcg aatggtcacg
    56041 gataccgcat ttttattata attactatgt tttccaatac tcgactggct tttctgctgc
    56101 ttcagcactg gcgaagaaaa tactaaacca ggaaccagag gcactagaga actacttggc
    56161 ttacctaaaa gcaggtaaca gcgattatcc tgtggaagta atgaaaaaag caggagttga
    56221 tatgacacag gctgcatata ttgaagatgc aatgtcgatg tttgaacaac gtctaaatga
    56281 attagaagaa ttgatcgatc gtttataagg ctttctattt ttgattttct cgaatagaaa
    56341 cgaaaaaaat acgtcggctc tcttgtaagg gagtcgacgt atttttt
//
LOCUS       DAFBSV010000007        49887 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.007, whole genome shotgun sequence.
ACCESSION   DAFBSV010000007 DAFBSV010000000
VERSION     DAFBSV010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49887
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.007"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(85..264)
                     /gene="rpmF"
                     /locus_tag="LLB18_000457"
     CDS             complement(85..264)
                     /gene="rpmF"
                     /locus_tag="LLB18_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBK5243487.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(322..891)
                     /locus_tag="LLB18_000458"
     CDS             complement(322..891)
                     /locus_tag="LLB18_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBK5243488.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1077..1979
                     /locus_tag="LLB18_000459"
     CDS             1077..1979
                     /locus_tag="LLB18_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK5243489.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="LLB18_000460"
     CDS             complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="LLB18_000460"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBK5243490.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="LLB18_000461"
     CDS             complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="LLB18_000461"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBK5243491.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="LLB18_000462"
     CDS             complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="LLB18_000462"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBK5243492.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8547..8732
                     /locus_tag="LLB18_000463"
     CDS             8547..8732
                     /locus_tag="LLB18_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HBK5243493.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8794..9990)
                     /locus_tag="LLB18_000464"
     CDS             complement(8794..9990)
                     /locus_tag="LLB18_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBK5243494.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10160..11596)
                     /locus_tag="LLB18_000465"
     CDS             complement(10160..11596)
                     /locus_tag="LLB18_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBK5243495.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11889..12698
                     /locus_tag="LLB18_000466"
     CDS             11889..12698
                     /locus_tag="LLB18_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBK5243496.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            complement(12884..15037)
                     /locus_tag="LLB18_000467"
     CDS             complement(12884..15037)
                     /locus_tag="LLB18_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBK5243497.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(15331..16179)
                     /locus_tag="LLB18_000468"
     CDS             complement(15331..16179)
                     /locus_tag="LLB18_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBK5243498.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(16403..18343)
                     /gene="thrS"
                     /locus_tag="LLB18_000469"
     CDS             complement(16403..18343)
                     /gene="thrS"
                     /locus_tag="LLB18_000469"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBK5243499.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(18680..18859)
                     /locus_tag="LLB18_000470"
     CDS             complement(18680..18859)
                     /locus_tag="LLB18_000470"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HBK5243500.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(18906..20729)
                     /gene="cadA"
                     /locus_tag="LLB18_000471"
     CDS             complement(18906..20729)
                     /gene="cadA"
                     /locus_tag="LLB18_000471"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBK5243501.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            21007..23286
                     /locus_tag="LLB18_000472"
     CDS             21007..23286
                     /locus_tag="LLB18_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK5243502.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(23379..24026)
                     /locus_tag="LLB18_000473"
     CDS             complement(23379..24026)
                     /locus_tag="LLB18_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243503.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(24205..24924)
                     /locus_tag="LLB18_000474"
     CDS             complement(24205..24924)
                     /locus_tag="LLB18_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5243504.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(25055..26206)
                     /locus_tag="LLB18_000475"
     CDS             complement(25055..26206)
                     /locus_tag="LLB18_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBK5243505.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(26423..27163)
                     /locus_tag="LLB18_000476"
     CDS             complement(26423..27163)
                     /locus_tag="LLB18_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBK5243506.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(27167..27490)
                     /gene="rsfS"
                     /locus_tag="LLB18_000477"
     CDS             complement(27167..27490)
                     /gene="rsfS"
                     /locus_tag="LLB18_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBK5243507.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(27547..28140)
                     /gene="yqeK"
                     /locus_tag="LLB18_000478"
     CDS             complement(27547..28140)
                     /gene="yqeK"
                     /locus_tag="LLB18_000478"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBK5243508.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(28124..28774)
                     /locus_tag="LLB18_000479"
     CDS             complement(28124..28774)
                     /locus_tag="LLB18_000479"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBK5243509.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(28784..29095)
                     /gene="yhbY"
                     /locus_tag="LLB18_000480"
     CDS             complement(28784..29095)
                     /gene="yhbY"
                     /locus_tag="LLB18_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HBK5243510.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(29111..30220)
                     /gene="yqeH"
                     /locus_tag="LLB18_000481"
     CDS             complement(29111..30220)
                     /gene="yqeH"
                     /locus_tag="LLB18_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HBK5243511.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(30217..30744)
                     /locus_tag="LLB18_000482"
     CDS             complement(30217..30744)
                     /locus_tag="LLB18_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HBK5243512.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(30924..31709)
                     /locus_tag="LLB18_000483"
     CDS             complement(30924..31709)
                     /locus_tag="LLB18_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HBK5243513.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(31702..32571)
                     /locus_tag="LLB18_000484"
     CDS             complement(31702..32571)
                     /locus_tag="LLB18_000484"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBK5243514.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKAAIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(32572..33951)
                     /locus_tag="LLB18_000485"
     CDS             complement(32572..33951)
                     /locus_tag="LLB18_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBK5243515.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(33959..34378)
                     /gene="fabZ"
                     /locus_tag="LLB18_000486"
     CDS             complement(33959..34378)
                     /gene="fabZ"
                     /locus_tag="LLB18_000486"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBK5243516.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(34403..34879)
                     /gene="accB"
                     /locus_tag="LLB18_000487"
     CDS             complement(34403..34879)
                     /gene="accB"
                     /locus_tag="LLB18_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBK5243517.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(34882..36117)
                     /gene="fabF"
                     /locus_tag="LLB18_000488"
     CDS             complement(34882..36117)
                     /gene="fabF"
                     /locus_tag="LLB18_000488"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBK5243518.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(36136..36873)
                     /gene="fabG"
                     /locus_tag="LLB18_000489"
     CDS             complement(36136..36873)
                     /gene="fabG"
                     /locus_tag="LLB18_000489"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBK5243519.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(36885..37802)
                     /gene="fabD"
                     /locus_tag="LLB18_000490"
     CDS             complement(36885..37802)
                     /gene="fabD"
                     /locus_tag="LLB18_000490"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBK5243520.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(37909..38133)
                     /locus_tag="LLB18_000491"
     CDS             complement(37909..38133)
                     /locus_tag="LLB18_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBK5243521.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(38186..39148)
                     /locus_tag="LLB18_000492"
     CDS             complement(38186..39148)
                     /locus_tag="LLB18_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBK5243522.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(39158..39598)
                     /locus_tag="LLB18_000493"
     CDS             complement(39158..39598)
                     /locus_tag="LLB18_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK5243523.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            39904..40869
                     /locus_tag="LLB18_000494"
     CDS             39904..40869
                     /locus_tag="LLB18_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBK5243524.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(40926..41156)
                     /locus_tag="LLB18_000495"
     CDS             complement(40926..41156)
                     /locus_tag="LLB18_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HBK5243525.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(41242..42129)
                     /locus_tag="LLB18_000496"
     CDS             complement(41242..42129)
                     /locus_tag="LLB18_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBK5243526.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(42218..43441)
                     /locus_tag="LLB18_000497"
     CDS             complement(42218..43441)
                     /locus_tag="LLB18_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBK5243527.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(43458..44504)
                     /locus_tag="LLB18_000498"
     CDS             complement(43458..44504)
                     /locus_tag="LLB18_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBK5243528.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(44668..46395)
                     /gene="ptsP"
                     /locus_tag="LLB18_000499"
     CDS             complement(44668..46395)
                     /gene="ptsP"
                     /locus_tag="LLB18_000499"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBK5243529.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
     gene            complement(46395..46661)
                     /locus_tag="LLB18_000500"
     CDS             complement(46395..46661)
                     /locus_tag="LLB18_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HBK5243530.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            47140..49374
                     /locus_tag="LLB18_000501"
     CDS             47140..49374
                     /locus_tag="LLB18_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK5243531.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            49522..49842
                     /locus_tag="LLB18_000502"
     CDS             49522..49842
                     /locus_tag="LLB18_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBK5243532.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
BASE COUNT        14253 a        10711 c         8730 g        16193 t
ORIGIN      
        1 attttttatt taccgactac aaaaaaataa acctcaaggc tccatggtta gccttgaggt
       61 tttacatttt ctaattaaaa tgtattaagc ttcttttgac attacgtcct taccatcata
      121 gtaaccacaa tttgcacata cgtgatggct ttttttcatt tcaccacagt ttggacattc
      181 gtttaaccct ttgattgtca atttgtagtg tgtacgacgt tttgcttttt tagcttttga
      241 tgttcttcta gctggtactg ccattttgct acacctcctt gtaaagtctt gtatctaaat
      301 tagacacaat atattccaat cttacttgtt atcgtcgtct tttgatttag aatcaaaaag
      361 ttcagatagt tttgcaagac gaggatcaat tttattctcg gcttcttcca tttttctgcg
      421 ctggtattct tcttcggaaa caacttccca atcattgcct tttggaagtt ctgttgctgc
      481 ttcctcttct tttgtcaata cccgcattgg aatcgccaat aagatgttgt cttcaatcga
      541 ctctgctaaa ttcaataatg gaccttcaat tagcaaaatc tcatctgcag acatttgttc
      601 atctctactt tggaattgtt cttctgtcat gaatacttcg tctacagaaa aatccatggg
      661 cagttcaaca ggttctagtg aacgtgttga aggaactgtc aaagtcgtct gcacagtgta
      721 atgaacgata tagcctttct tatcaactga gaccaaacct tcgacttcca ctggcgcaac
      781 atcaagtatt aaattgtctc gcttcatgag agcggctttc aagtcgagcg tctcatgaaa
      841 agttaacggt gtctcctggt attttctcaa ttccaataaa gaccatttca tttttcatca
      901 ctcctaagca acaaaagcaa ttatacaggg caaaaagcat gttgtcaatg aaattttctt
      961 gacaccttgc agttcataaa aaaacagaaa aatctttatt agaaagcctc tgtttgctat
     1021 catcctcaga atcatttaca ataatcatta ttccattaaa ggagcggatg atcttcatga
     1081 acacgaaaga tatcgaatac tatgtccaaa tcgtcaaaca aaaaaatttt acgaaagtgg
     1141 ctaattattt ccgtgtgagc caacctacta ttacatatgc attacaacgt cttgaaaaag
     1201 agtttgacac cgtacttatt acaagagatc gatcgcatca cgaattaatc gtcacgcctt
     1261 ctggaaagca gctgtttctc catgcacaaa ccattctcca agagatttct actgcaagag
     1321 ctgaaatcac tcagttgcaa aagaaaaagc ttcgttttgg catgcctcct attatcggca
     1381 atgaatactt tcctaaactg tcaagttact ttatcaagca tgaattgatg aatcaaattg
     1441 agattaccga tggaggctct cgggacttat acgggatgat ccgacaaggg aggatcgatt
     1501 tagctgtatt aggctcaaca cagccaatcg tggatcaata tttagaaaca gagttacttt
     1561 tggacaaacg tttcatgatc gtcgtgccac ctacacatcc tctttccaag caggatactg
     1621 tctctttcaa agatatagca gatgaacagt ttgtactatt gaacgaacat tatgtccacc
     1681 ccgcagcatt cactaagctt tctaaacaaa cacatactca tccaaaagtt gtttatcaaa
     1741 gcaatgactt gacgatttta aagagtatgg tccgagaaaa tgtgggtatc ggttttttgg
     1801 cagagattgc tgtccatcct gaagatcatt tagtttgcct ccctctttca gatgaagttc
     1861 agcctcgctt cttgatttca ttggcaaaac gaacacagca gatcgtcacg cctcttcaag
     1921 aacaagtagt ccaagttatc catgaattcg ttacagcaca aaaaaacagc tcttcgtaaa
     1981 agaagagctg tttttatttt ttattaagct aaattagata gctgttgttt cgccacggta
     2041 aacgatgccg cgacgtgaat caacggtaat caattcacct tctgtaattg ttgttgttgc
     2101 gcctttagca ccaacgatta caggaatatc ttgtgcaatt cctacaactg cagcgtgaga
     2161 agtcaatccg ccttcttcaa cgataacagc agctgctttt tcgattgcag gcatatattc
     2221 tttgtcagtt gatggtacaa ctagaaccat tccgtctttt gcttttttta cagcttcttc
     2281 agcagatgaa gcaataactg catttgcaac gacagatttt tgtccaacgc cttgagcttc
     2341 taataattta gaaccaatca tttgaatttt catcacgtta gttgttccgc gttcaccaac
     2401 tggtacacca gcagtgatca agattaaatc gccttctgat gcgaaaccta attcaacagc
     2461 ttttttagct gctagttcaa acatttcatc agttgttgat ggtttttcag caactgttgg
     2521 gtaaacgccc cagtttaaca tcaaaccacg ttttgtgcgt tcgtcaaaag taacagccaa
     2581 gatatctgca tctggacgat attttgaaat catttttgca gtgtatcctg attcagttgc
     2641 agcaacgatt gttttcacgc ctagattttt tgcagcacga gctacagata aaccgattgt
     2701 ttcagttaca tctgttttat cgaattcgtt caattggaat gtacctaatt ctgataatgc
     2761 attttcagct tcttggtcga tacgtgccat tgttgaaaca gcttcaactg ggtagtcccc
     2821 gtttgcagat tcaccagata gcattgttgc atctgtgcca tcaaatacag cgttagcaac
     2881 gtcagaagct tccgcacgtg ttggacgtgg gttttcttgc attgattcta acatttgtgt
     2941 agcagtgata actgggatac cagcagcatt acattttttg ataatgcgtt tttgaaccat
     3001 tggtactagt tcagctggga tttcaacacc catatctccg cgggcaatca taacaccgtc
     3061 agaaactttg atgatttcgt caatgttgtc gataccttct tgagattcga ttttagggaa
     3121 gatttgaaca tgagtcatgt ctttttcttc taagatttcg cggatatcta gaacgtcttg
     3181 tgctttacgt acaaaacttg cagcgataaa gtcgatatcg ttgtctaaac caaaacgaat
     3241 atcgtcagca tcttttggag taatacctgg caaactaata gaaacgcctg gtgcatttac
     3301 ccctttacgt gatcctagca tacctgcatt tttaacttct acgactaatt cacggtttgc
     3361 ttcgtctttt tcaatgattt gcatatcgat caaaccatca tcaaataaaa tgtgtccgcc
     3421 aacgtgaaca tcgtcaaata atcctgggta agtaaccgcg attttttctt ttgaacctac
     3481 atgttcagga tccatagaga tgcgtgtttg atctcctact tcaaatttga tgtatcctgc
     3541 acgaccaaaa tcagcttctg ttgtgccttg aacagttgta cggatttcag ctccttttgt
     3601 atctaaaaga ataccgacat cttttcctgt ctttttaact gcttcacgga ccatagtcat
     3661 acgtgataat tgttcttcat ggtcaccatg agaaaaatta aagcggaaga catttgcccc
     3721 agattcaatc aattgagaaa taatttctac tgagttactt gctggtccta atgtactaac
     3781 gattttggtt tttttcattt aaaaaactct cccattcaat tttgtttatt taaagctgta
     3841 cacagcttaa atagcttggt ttctttcact cttaaaatga aagtgaatta tttagatcat
     3901 atagtgataa gtctggttta tgtttgttgt tttcaagtgt atcaatgatg tcagacgcaa
     3961 cgatttcgtt gtcatggata ccgacacata atccaccttt tccttcttga agcaattcga
     4021 cagcgtaagc accgaattta cttgccaaca cgcggtcgcg tgcgcttggt gctccaccac
     4081 ggacaacgtg tcccaagata gatacacgtg tatgatagtc accaaattct gaaagtttct
     4141 cagcgaattc atttccgccc attacacctt cagccaagat gatcaagcaa tgtttcttcc
     4201 cgcgatcgcg gccttcttgg atttttttag caactgaagc catatcaaaa tcatgttctg
     4261 ggatgatgat ttcatccgct ccgccagcca cacctgacca taaagcgatg tctcctgcat
     4321 tgcgtcccat tacttcgata acgaatgtac gaacatgaga agtcgctgtg tcacgaatac
     4381 ggtcaattga ttctagtact gtattgattg ctgtatcaaa accgattgtg aaatcagtcc
     4441 caggaatatc attatcgatt gttccaggaa tacctactgc tgggaaaccg cgttttgtca
     4501 aagccattgc gccatgataa gagccgtctc ctccgataac cactagacct tcgattccga
     4561 attttttcaa ttgttcgatt ccttttaatt gaccttcttc agttgcaaat tctggataac
     4621 gtgcagaata caagaatgta ccaccacgtt ggatcttgtc acctacatct gccacatcaa
     4681 gacgacgaat atctccagca actaaaccgg caaaaccata attgatcccg tatacttcca
     4741 gtccttcgta aataccttta cgaacaacgg cacgaacagc tgcattcatt ccaggtgcgt
     4801 ctccgccact ggtcaaaatt ccgatgcgtt tcataataaa cattcacctc attaaaatac
     4861 tttatcctaa gtatgactta ggtttacaac catttttgcg ttaaccacga ctaacattct
     4921 aacattattt ttctcacttg tcttgattta cggataaaaa aatgaaaaaa aatgaaagca
     4981 agtagtattt tttaccgtaa gttatttgaa aaccacatta tcttcgccaa gcagataaat
     5041 aagttgcccc tttatactct tgctgtcatc cacccaataa gcatctgaca gaactacttt
     5101 tcgttgcgtt ttttcgtgat acataactac tggtatatat cctgggtgtt tctgaaaaat
     5161 cacttgtaat tgtttcatta tctcgggatc ttcccgttct tctgtaatac gcaaatagca
     5221 agtttgtgaa ggatactggg cttctaactg gttaggatca gcaaagcttt ctccaattag
     5281 ttgcagttcc tgattatatt tgctgatttc gctccgccct tgaacaaaga tcactcgatc
     5341 aacggcaaac aaattacgat atttacgata aagagttgga aaaactgtga cagaaatttc
     5401 tccactactg tcggttcctt caacaaaggc catcagttct cctttttttg tccgaatttc
     5461 tctaacttcc ttgatcatca ctaataaatt gactggttga ttagggacga tatctgtaat
     5521 cagctgaact tgtttagcta aacgaagacg atcaaaccct tctgcaggat gacctgacaa
     5581 ataaatacct aagtactcct cttccagctt caagcgttct tctagtgtat agtcagcgac
     5641 ttcttcttct tttaatgcca tgattcccag caagtcaaga cttccaccac tgtaaacgat
     5701 attttggatt tttccttcga gatcaagcat caattgtttc ctgttaggag ataattcatc
     5761 aaaaactcct actgctgtca gtgattgcag taactctaat ttcagccaac gcttatcgat
     5821 ccgtatgagg aattgatcca ctgactggaa cgggccattt tgttttcttt cgtttaatat
     5881 atcttctaca aaatcacgcc gaataccttt tatcgctgtc agtccgaatc tgatttcttc
     5941 cttattgacc aactcaaaac tggaattact ttgattaatg gacggcgagg aaagtttgag
     6001 tttattttta cgtgcttctg caatatattc tttcaatttt gatgtgttat gccgaacaga
     6061 attcatcagg ctggtaaaga aagcacctgg atgatgggct tttagatacg ccatttggaa
     6121 tcccacgaat gaataagcaa atgcatgtga ccgattgaat ccatagtttg caaatttttc
     6181 gatatattca tatacggtcg ctgctgtttt ttccgaatat ccctgttgta atgctcctga
     6241 tacaaaatgc gacttttctt catctaatac gtcttttttc tttttactca ctgcccgtcg
     6301 cagaatatct gactgcccta atgtaaatcc agccatagtc gaggcgatct gcatgatttg
     6361 ttcctgatag acgatcactc catatgtgtt tttcaaaatc gggatcagtg aatcatctgg
     6421 gtagcgaatg gcttcttttc ctttcttcct ggcaatgaag gtatctatat tttgcatagg
     6481 gcctggtcga tacaatgcat tgactgcggc aatatcttcg atgttttctg gatctaatct
     6541 tcgtaaaacg ttccggatac cagcagattc aaattgaaat actcctgagg tttcgcctcg
     6601 ttgaaacaag agcagcgttt ttgcatcatt tagcgggatc tcttttaatc ggatctcata
     6661 cccttctact cgcttaacag ctttcaaagt aaaatcaata atcgataagt tgcgtagtcc
     6721 taaaaagtcc attttcaaaa gaccgattgc ttctacctca ttcatcgtat actgggtcag
     6781 aaaagcttca tcagaaccgc gttggagcgg aactagttca agtagattct tatcgctgat
     6841 aactacacct gctgcgtgag tcgaaacatg tcttggcaat ccttctaaaa tcactgcagt
     6901 tttgaataaa agttggtttt tttcgcttgc ctgaactaat tctactaatt gatgcgaagt
     6961 tttataagct tgggtcaatg tgattttcaa ttgattgggt attgcttttg accagcggtt
     7021 tgcttcactt tgcgataaac caaacactct agctgcatct ctaagaacca tttttgctgc
     7081 cattgtgcca aatgttgcga tttgtgccat atgatattgt ccatactttt ctcgaacata
     7141 attcaatact tcttcacgtc gattgtcagg aatatccaaa tcgatatctg gcatcgtaaa
     7201 gcgttcgggg tttaaaaagc gttcgaacag caaatcatat tctaatggat ccacatctgt
     7261 gatttctaac acataggcta ctaatgaacc cgcagcagaa ccacgacctg caccggtaac
     7321 gattttgttt ctatgagcaa aagccattac atcccatacg atcaagaaat aatcatcgaa
     7381 tcccatttga tggatgacag ataactcgta gtccaaacgt tcttggtatt cctttgtata
     7441 gtcagtgatt cggcgttcca cttgcgaata gcataactct cttaaatatt ctccagcttg
     7501 ttttccatta ggaactggat aatgcggaag taatttctga tggaactgga attcaaatga
     7561 aatcgattca gctaaacgct gggcgcctat tacagcttgg gaaagacccg ctttttcgaa
     7621 tcgtttgatc atttcttgtt ctgaaagaag atagacattt gctgttagtg gtaaagatgc
     7681 agataaattt tctaaaggta tttggcttcc ctctttgata tgtttcatca cttcaagtgc
     7741 aaaaagttct tcttgttgta aactagcgat gggatgtaat gcacaaagcg aataattttc
     7801 ttttatcaca tactgatacc attcaggcaa ttgatcaggc gtgttttctg tcaagccgat
     7861 ataaaaattt ctagtaaaaa cattttcaag taaaaactgc caatgaccga aaaagttatc
     7921 ctctttattg aaagcctcag aaacagaatg atttgccgga acaacaaacg ctagatggtc
     7981 ggtttctgtc atttctgcaa gttccaattt ttcttggatc atttttcggc tggaaagttt
     8041 catcagctgc tgataaccta tttcatcttt tgcgtacgca agcaagccat aatttttttc
     8101 ttcataagta taactaagat gtaatccaat gattggctgt actccttctt ctacacaaat
     8161 acgatagaat tcaggtgcac cgtataagac atctttatcc gttatggcta atgaagtgta
     8221 gccttgtttt tttgcttctt gtacatattc tcgaatacgt atcgtacttt gtaaaagaga
     8281 ataagaagta attgtataaa gttgtgggaa aaacatcttg cattccgcct tttttttcgt
     8341 taaaattcac tagcgttaaa aggtttgatc cttttacttt cattaagata gcaggcgctg
     8401 aagttgatta ttccacttca tttgcttgct tgtaatctgt aggaatgagt tctttcgcaa
     8461 gaactcaaat tttattgaga tttggtctcg tttctttaca ttcaaagaaa atctggtaaa
     8521 attaagatag aaaagaggtg ttctttatgc gatatatcgt tacattattc tgggctgtcg
     8581 ttctaggtca agtagtcggt tatattggtg ctgcattaac aagcggaaca tatgatttta
     8641 ctttgacaac aatcatttca ttcattgcgg gtgtcattat ccttttgatt ggtgcagttg
     8701 cgccaagaaa agaaacctct gcccattcgt aaaaaaacag ccaagagctt gagatttctc
     8761 aagctctttt ttattttcta ctcctcacca ccattataat ctgctgcgaa gaactttacg
     8821 aaagttgaat aaagaaagaa gaatatttga cagaacaaac aaacttgtca caataaaaac
     8881 agcactgtaa ttataagcat gcgcgactgt cgatcctagc atgggaccta aaacttgtcc
     8941 aaagttgcta aacatctgat tgtagctata gattcggctg actccttctt gaggcgtaat
     9001 cttactgatc agtgtattga cagaaggcat caaagcgcca gttgaaaagc ctaaaataaa
     9061 gcgaagtata cctaattgga gcggtgtagt gacgaatgcc ataggtaaat aacagcaaaa
     9121 tgataaaatg agtcctccaa ttagaacttt ttgattccca atcttatccc ctagttttcc
     9181 tagtttcggt gaagaaaaga cagcggaaac accagctatc gaaacaatca agccgctgac
     9241 aaaaaggata ttttctgtac ttccgctcaa ttcacgaata tataaggtca aaatagggct
     9301 gatcgtagtg attcctatct gtaaaatcaa ggtcgtaatg aagagaccga tcaaaataga
     9361 gagatgatcc atttttgaaa aaatttcttt ggtgcttatc agatcttttt tctcgattgg
     9421 atggaaatct tctttgacta agaaaatggt caataccgtt gtgatcatca acaaagcccc
     9481 tgtgatcaag aatacatttt ccataccaaa ccactgagcc agtgcaccgc ccattgaagg
     9541 tccgatcaga tttccagcaa tcgctccggt agacaatgtt cctaacgccc atccgctctt
     9601 ttctctaggt gcctgtgaag caatcatcgc tgtggcattt ggaatatatc cagacaaaat
     9661 cccattccaa aaccgcatga tcaaaagcca atacgcgttt ggtacaaaag ccaaagatcc
     9721 cattgttaat gtcatccctg ctgctgcacg gatcatcatg agttttcggc cttttcgatc
     9781 agctagattt ccccagattg gtgcaaccac ggcagatgca aaagcagtca cagagattgc
     9841 tagtcccgaa aacaattcga tttgatcttt tggtgttcct agttgctcaa cataaactgg
     9901 tatgaatggc ataactaaac taatacttgc accagtgaaa aaacagccaa tccacgcaat
     9961 cactaaattt tttctccaat taatctccat ctatcatccc tctttcgtct cttttatcat
    10021 acctattttc gaataaacaa gcaacgatct cgccagtaaa aagagaaaaa tcccgcaaag
    10081 gtcattttat atgtaacgtt ctttttatgt aaaacaaaaa gagatcagaa caaatactgt
    10141 tccaatccct tctctttagt taaattgttg ctagaatgat gaagttgata atgaataaaa
    10201 tatcaacgat ccacaaagca acagaaactt gattgtattt tcctttgatt actttcacaa
    10261 ttgtatagaa aataaatcct gctgcaatcc cataggaaat gctatagcac aatcccataa
    10321 agatcgatgc aaagaaggcc ggtaaagctt cttccatatc tagccatttg atgtctgcaa
    10381 aagaagccat catcattact ccaactaaaa tcaatgctgg cgcagttgct tgatttggta
    10441 caatggcgat cagtggagag aataaactac ttaatgcgaa tagcactgcc actactactg
    10501 aagtcaaacc agtacgtcca ccggccccga tcccagctgc agattcgaca taagttgttg
    10561 tattcgatgt accaaagata gcccccacag aagtagcgat cgcatcggca aatagtgctt
    10621 tatccatttt tgttttgaac ccacgaccat cttccaacgc gatctcgtct tcttttgaga
    10681 aaatacctgt gcggcgtcct gtaccgataa atgttccgat cgtatcgaaa gtatcagata
    10741 aactgaatgc gatgatcgtc atcaatactt gaggaatctt ggaagaatca ctgaataaag
    10801 attgcatgcc ttcagaacca aatgctgcac cgaaagttgt tcctaattct ttaaatgaat
    10861 tacctaacga attcgtttgc caatcaatgg aacttaaatc aacaacaccc ataaaaatac
    10921 caaggactgt ggtcgctacg ataccgataa gaatagcccc acggacattt tttacaacta
    10981 aaatggctgt cagtaccaaa ccaatcacag ccaataagat aggagcgttg tcaaagttgg
    11041 ctaacgcagg gacgattcca ccatttatcg taacatttgt cgcttttccg ccttcaacga
    11101 cagagctcga aatagctgac tggtctgctg aaaaagataa gaatcctgca tttttgattc
    11161 cgacatacgc aacgaaaata ccgatcccgc caccaatcgc atgttgaaga ctttcgggaa
    11221 tcgcccgaat aatcattttt cgaatatttg tgacagtaat aaaaatattg attaatccgc
    11281 aaataaacac cattgccaag gcttgttgcc aagaataacc aagcccaaaa acgaccgtaa
    11341 aagtgaaaaa tgcgttcaat cccataccag gtgcctgagc atatggtaca tttgcgaaca
    11401 atcccattac cagcgtacca ataatcgatg caatgattgt cgctagaaat actgcttgga
    11461 agggcatacc tgatgctgac aaaatcgtcg gatttacgaa taagatataa ctcatggcaa
    11521 agaatgtcgt tactcccgcc attatttcag ttgatacatt tgtattgttt ttctttaaac
    11581 cgaaaaactt ttccataaaa agttccactc cctgaatttt tttctgatgg aaaactataa
    11641 taataaaaaa taagtaaaat agggcaaatc catcgaacaa tttcaaatta tatagacgtt
    11701 tcattcgctt ttcaacgttt ttttaacaaa aaaagcgaaa ataatactta acgttcgtgt
    11761 ttagcttatg tttagctatt tatatagcca taactgtagt ttttgttagg aatagctgat
    11821 tgctcttgtt aattacctaa aatatgctag actaaaacaa atgctagttg aggaaggaag
    11881 gacccttatt gaataaaaaa ttaattgcca tcgatctgga cggaactacc ctcaatcaag
    11941 attcgatgat tacatctaaa acaaaagaga ctctaaaaaa agcaatcaat gccggtcatc
    12001 atgtcagtat tgctacagga cgcccattcc gaatgagcca tcagttttac caacaattag
    12061 aattaacaac accgatggtt aattttaacg gcgcattagt acacatccct aatcagcact
    12121 gggatggtga aagagaaacg ttgatcaatc gtgaaatcgc ttttgaaatc ttatcgcaaa
    12181 aaaagcagct aaatttagat tttatcgctg ctgaaaatcg tgatactttt tttattgaca
    12241 gttttgattt ctttgatgaa aaaatttttg cttcttctcg tccaggagag aagaatttgc
    12301 tttctcctaa aaatttgacg acaaatccta catctttgct tgtccgaaca gacaaacgtt
    12361 ttgcaggagc tgtatctgct gaattaacac gtcaatttgg cagttatgtc gatgttcgga
    12421 catggggtgg acctactgcc atcttagaga ttgtttcaaa aggaatccaa aaagcaaaag
    12481 gcgtgcaaga gattgctaac tacctgtcta tcgatcaaaa agacgtcatt gcctttggtg
    12541 acgagcataa tgatttggaa ttgttggatt atgcaggttg gggagtagct atggctaacg
    12601 gtactgacca actcaaaggc attgcaaatg atgtcactcc tttgagcaat caggaagacg
    12661 gtttagctgt ttatctggaa aaactactta aactataata gagaattaga ttccacaaaa
    12721 aagaggttgt gacaattttt gtcacaacct tttttgccga gtaaacggtg ttcaaaagcc
    12781 agtttctcgg tatgaagtca aatttaagca aaaatgtgag aagctatttt cacaaaattt
    12841 ttcttcatac tcgaaactaa gcggcttttt cacgacctct tttttatttt gccatgaaca
    12901 tatcataata cgcgtccatt atttctttag caatcgtcaa gtttatgtgg tcttgttcgt
    12961 ctaataagtt cggcaagaca acactgatgg caatttccgg attgtctgtt ggtccgtatg
    13021 ccacgatatt actattgact gtcgcaatat ctggatgacc ttccgcaacc gtttctgcag
    13081 tccctgtttt tgcggaaagg tccattttcg cactggctaa tggtttggct gttgtgtaag
    13141 gatcggtacc atggacaact tggtggaatc cttcacggag gatcgccata ttttctgcag
    13201 aaatattgac cgtattttct actgttgtgc caatttcttt cttcacttca cccaagtttc
    13261 cattttcgtc attgccatag atcgctttga ctaggtgcgg ctgtactcgt ttcccgccat
    13321 tagcgactgt tgaagcatat tgagctaatt ggattggtgt atatgtgtca aactgtccaa
    13381 atgccaaatc ggtaaagtta cctggagcat accattcttt gccattatcc gcattgaact
    13441 tcttcatata atcaacagaa cgtgagatcc caggagattc attcggcaaa tcgatcccag
    13501 tcgttgtacc aagaccaaac tctttgaaag agtctctcaa ttgctgataa gctttagctt
    13561 cttcatctaa actaggtagt cccattccag gtgtatagtc tagtcctaac atctttaacg
    13621 ccactttgat catatacgta ttagaagaca attccgatgc tttgactgca tcaagagcaa
    13681 cttgtccgct tcgattaaag acagagcttt tttctgaagc accttgcaga cgaatcggct
    13741 catcaatcaa aacttgattt ccgctgatcg cgttacttgc ccagcctgct gtcaaagtac
    13801 cagccttgac tacagaccct ggatcaaagg cgctagtaat cgtgcctaaa gcattctcgg
    13861 tgatttcttt ggaaccttgt tcatgactga aaccagtcat tgctagcact tctcctgtct
    13921 gaggattcat agccactgca taagcaccag gcgaatactg tgctttgccg ttgttgatca
    13981 atgtttgata attccttttc aaaatttctt ctacttttga ttggaattct gcattcatag
    14041 ataacattaa attagaacct ttttccccag agaagatttc tttttgattc gaaacatttc
    14101 cttcattatc aagggaaact tcatattggg ttttggttcc ttgcaggaca tcttcatatt
    14161 gtttttccaa ataactttgt cctacacggt cattccgaga ataacctttt gctaggtatt
    14221 tctctgcttc atctgctgga agtccttgct tttcagtcgt cacactgcca agaatacttt
    14281 tcagtgaact tgctgcatta tattctcgtg tccagtctgt gccagtcgaa actcctggaa
    14341 gttcagaagc gcgttctgcc acaacagcta actcttgatc agtaacacca gagtttttga
    14401 tatagacagt gtttaattca tatgcactat tcatccgttt aaagatggta gcaattttta
    14461 attgctcctc gtttaaatta atctcatcag ctgtgacttt attgaccatc gcactatatt
    14521 gttcgctgtt ccctaattgc ttttcttttg ccgaaagtct ttttgtggct tctttcaaat
    14581 gtttgggatc agccagccaa aaatcttttt tatctctatc tgtcagattt tcatctaccg
    14641 gaacatcgat cagcgagttc agcttcgttg cgatttcaag caaatcttta gccgtaactt
    14701 gtgttcctct cgtatatgtg atggcctgat tcgctttatt cgtaactaaa gcttttcctg
    14761 tggagtcgta gatcattccg cgaggagtac tttcttggac cgtaatcgta gaagtagact
    14821 tcactcgcgc ctccatctct tcgccgttca cgatctgcaa ataacccaat ctagcaatca
    14881 acgcaacaaa taacgtaaat ataatgaaaa aaagaaaatt taagcgaaaa ggaacatggg
    14941 accggcgaaa cgttttgttc ttaggttctt gtgcaccttt tcttattttt tctaaccaag
    15001 aagtatttaa tatttttttc ataaaatctt tcatcatttc ctatccttcc gcctatttac
    15061 attcatgctt cattgtaccc aaaaacttct taataaaaaa gaaaaaatgg gcggagcaag
    15121 aaattcttta cctaatttca agataaaatc aactttttgt ttcacagcaa tcacttaaag
    15181 ttacatatcc aactattttt ttcattaaaa aataaactta tttttgaaaa ttatgttttc
    15241 ttaagtcgtg aaacactttg atggatcatt tatttgtgga aaactacgtt ttgttattct
    15301 aaaaaactta tataaaaaat agtaaggttt ttatttcgaa tccataaaat attcttggat
    15361 tgcttctcgt gtttttttca ctttttcgct aagcttttcg tttttagcca tatagaaata
    15421 aaaaatgata tcgatcgtag caaattgggc caaaagtgaa ttagttgccg cacttcgatt
    15481 cgtgatttct tttggtctag atgtttgtac gagtacatcg gctatcttgc taagcgggtt
    15541 atttccaaat tgcgtcaacg caatgatttc gatattcatg cttttcgcca gctcggctaa
    15601 tgcgactaca tctgcacttc tacctgagtt tgaaacaagc caaagcactt tctttttctc
    15661 attgctgaca agttgcggga gcaagacgtg gatatctttt tcaaaaatga ttggcttacc
    15721 gacacgagac catttttgca gaatatcttc tactactaaa gaagaggcgc caaccccata
    15781 taaaaaaaca gtctctgccg attccaaaca ctctacgact ttttggatcg tttcttcttc
    15841 tagaatatct actgtttctt ttatcgctac ttgtgcattg ttaccaagtt tgtttttgat
    15901 agagtaaaag gactcatttg cttctatatc actaaaacct tcatcgattc cagtctgtag
    15961 ttctgttgaa atcgtgattt tgaagtccgt cagactttga aaaccgattt ttttggaaaa
    16021 acgtacaact gtcggcgcac tcaacccgga agcttctgct aattcattag ctgtcattgt
    16081 agggaccttc tcaatattac cgataatgta gttggccaac tttttttctg ctgaagaata
    16141 atcttccatc atactttcaa tacgactaat tacgctcata agttcctcca cccttttaat
    16201 gatagtctat gtaagtatac catatcagac ccttattcac ggtcgtatac tggataaaaa
    16261 acaaaaaaac aatccgccca acagaatatc ttatcccatc aatcccacag attctattga
    16321 gcatctgtgt ctttgaggaa tacctgttat ctattgttcg gattgctttc tatctactac
    16381 ttttttacag gaaatttacc tattagtttt ctctgctgta atttttgact tctgcttcca
    16441 tagcatcaat aaagatattc aaatcttcta cagctgtttc tttacttcca taacgacgta
    16501 cgttcactgt tgcatcttcc aattccttgt ctccaacaac taattggtaa gggatctttt
    16561 gtgtttgaga ggcacgtatc ttatagccca ttttttcatt acgatcatca acttctacac
    16621 gcaacccctt catttgcaaa cgttctttga tttcataagc ataatcgcca tgtgcatcaa
    16681 cagaaacagg gatgattgtt gcttgtatag gtgccaacca tgttggaaaa gcgcctttgt
    16741 atacttctgt taaataagcg acaaaacgtt ccattgtaga aacaattccg cggtggataa
    16801 ctactggacg atgcgtattt tccccgtctt ctccaacata tgtcaaatca aagcgctctg
    16861 gcaataagaa gtctaattgt atagttgata atgtttcttc tgtaccaaga gctgttttga
    16921 cttgaacatc tagttttggt ccgtaaaagg ctgcctcgcc ttctgcttca aagtaatcta
    16981 gttctaattc atccatagcg gctttcagca ttgcttgggc tttttcccac attgcgtcat
    17041 catcaaaata tttatctgta ttgtttggat cgcgatagct caagcggaaa cgataatctg
    17101 taatattgaa gtcagcatat actgccacca tcaattcaag cgtacgttta aattcatctt
    17161 tgatttgatc aggacgaaca aatgtatgac catcattcaa cgtcatttct cgtacacgtt
    17221 gtaaacctga caaagcacct gatttttcat agcgatgcat cattcctaat tcagcgatac
    17281 gaattggtaa ttcacgataa gaatggatcg tgtttttgta gaccatcatg tgatgagggc
    17341 agttcattgg gcgaagaaca agcatttcgc catctcccat atccattggc gggaacatgt
    17401 cttcttgata atgatcccag tgtccagatg ttttgtacaa ctcaacatct cccattattg
    17461 gtgtatatac atgttggtaa cctagactaa cttctttgtc tacgatataa cgttcgatcg
    17521 tgcgtcggat tgttgcccct tttggaagcc agaatggcaa accagaacct acttctgggg
    17581 aaaccatgaa caagtcaagt tcttttccta gtttacgatg gtctctttct tttgcttctt
    17641 cacggagacg gatatattct ttcaaagctt tcttgtcaaa aaaggctgtc ccgtatacac
    17701 gttgcatcat ttgattgttt gagtttccac gccaataagc acctgccact gataataatt
    17761 taaatacttg tatacggcca gtggatggaa catgtggtcc acgacacaaa tcgatgaatt
    17821 cgccttgttg ataagcagta atcacttctt cttctggcaa ttcactaatc agttctactt
    17881 tgtacggatc acttgcaaaa atttctaatg cttcctgttt tgaaagaaca cggcgttcga
    17941 tcggcagatt ttctttgacg attttcatca tttctgcttc gattgccggc aaatcttctg
    18001 cagttacttg gttttgtcca ttatctgtat cgtagtaaaa ccctgaatcg atagctggtc
    18061 caacgccaaa gtggatattt ggatagaggc gacgcatggc ttgggccatc aaatgagctg
    18121 ctgaatgacg gactaagcca agtgcatctt catggtctgg tgtgatgatc tcaatacttg
    18181 catcttcctc gattggacga gtcaaatcaa cgagttttcc gttcacttta ccagctaaag
    18241 ctttttttgc taagcttttt gaaatgcttt cagcaattgc caatgttgtt gttccagact
    18301 caaattcttt gactgcacca tctggaaaag taatttttat cataatagtt tcctccttga
    18361 aatgttttga ttgatcagat catcaagctg aaaaacaaaa aaatcctagc atctcttgaa
    18421 aagagatact aggacgaaaa gttcgtggtt ccacctaatg ttcaaacgca aatgcgttcc
    18481 tcaagcgttg taacggtccg accgcccttg cttcaacaag ggtttcgaaa gtggtcatcc
    18541 tttggttttc tcctggaaaa gtttcagcct agcttttcct ctcttatcga agactctcaa
    18601 attcagttgg ctttctcatc aatcaattat gtgtttattt aaccactaat aaatagaaaa
    18661 atcaagtggg aaactaaact tattttttcc attccccatt tacaccgtat gttccttttt
    18721 tcatctcatt gatgatgaca tggatgtgtt cttttggtgc ctgcgtgttt ttatgaacag
    18781 cttccgtgat atctttcatc atattttcta attgttccgg actgcgacct tctactaatt
    18841 cgacatgtac gaatggcata atgctctctc ctctttctga tcgttctttt ttcaactcga
    18901 ttctatcata ctatgtttgt cttgggtact gaatcaggaa aaatggctgg atcttttttt
    18961 gctctcaagg cactcaaaat agagaccgta tccacgactt cttgcaaaac agctccgaat
    19021 aatgcgggga ttagtcccgt acttgcaatt aacatcaaaa aaatacaaat aaagatgcca
    19081 atcagtacag actgtttcgc tattctcatc gtatctcttg aaatcactac tgcttttgct
    19141 acacgcaaga gatcatcttt caagatgacc gcatctgcac tttcactagc agctgtagaa
    19201 ccatgagccc ccattgcaat accgatatct gcagcagcaa gtgctggtgc gtcattcacg
    19261 ccgtctccta ccatcgcaac aggtctttga tctttaggga tactttctaa aatggtcagt
    19321 ttatcttgag gcaagctacg ggcatgtaca gaatctaatt ggactttttc tgcaatcgtt
    19381 tgagcaatgg cagatccatc cccggtgatc atcatcaaat ttttcacatc aagttttctt
    19441 agctccttga ttgtctttgc tgcttctggg cgaatctgat ccgaaaatag gatcgttcct
    19501 gcaaaagatc gatcaattgt tacatagatt gctgtattgg acgtttctat ttcttcagct
    19561 gaaacaaaag aggcacgtcc aatctttact tcatgattat tgactactgc ttggattcct
    19621 tgaccggtca cttctttcag ttgactaaca ggatacagtt ggctgttttt cacgttgttc
    19681 actaacgaac gagctaagat atggctagat tcctgttctg cactagctgc atacagaagt
    19741 agctcttctt tttttattcc attgactggc tgaatcgcct ctacttccaa tatccctttg
    19801 gtaagcgttc ctgttttatc aaaagcaatc gtttttgtac gtgcgagctt ttcaatcgtt
    19861 gttccagttt ttacaacgat cccgttttta cttgaacggc tcattcctgc aactaaagca
    19921 atgggcgcag ctagaatcag tggacaaggt gatgccacta ccagtacctc agcaaatcgt
    19981 aaagggtctt ttgagaacca ccaagaaata ccaccgatca aataagcaat caacgtgaaa
    20041 gggactgcat aacgatcagc taaacggaca aatcgggcag gcttttcttt tgattcttcg
    20101 actagtttaa taatcatttg atactggctg tctgcggcac gtttttcagc gatcatttgg
    20161 atcgatccgt ctccatttaa agaccctgac ataatctgat ctccaggttt cttggtttcc
    20221 gggcgggact cacctgtcaa agaagattca tcgaccgaag attctccttt ggtcactcga
    20281 ccatctgcgg gtacaagttc gccaggcttg actagtaact ggtcatcaat atttatttca
    20341 tcgattacta tatcctgcaa ttttccttct ttgaatcgat gggcaattct tggggtgtta
    20401 tctaacaaag actgcagttc tttacccgct cgtttattcg cgtaatcctc tagactatct
    20461 ccgcccgtaa gcatgatcaa tatcatcaaa ctagcccagt attctttgac ggctaatgtt
    20521 gcaaggattg cggtaatcgc taatacatct acgccatatc ttcctgaacg taacgtcttg
    20581 atcatttcca aaaacatcaa gaaggcgaga atccctccag taaatgcgac aatcgcaaat
    20641 gcaagggccg gctggtgaaa aacaaattca cttaataaag ctatcccacc aataagcaaa
    20701 gtaagtaaaa attttttgaa atgtgtcatt gttttttctc ctcttttatg tgacttagag
    20761 aggttagtaa taaatttcca gctgcctctt tcatcttaag catagtcctt gactagcact
    20821 ttttaaaaca ataggcctta attgaaaaca actatcacta tcagcgtttc caaaattcat
    20881 cagttctaca aacaaaaata ttcagcaagg attacttttt cgattcatca gttaaaaagt
    20941 accttttttc gaaaaactat gctatacttt taattcgtta tttacggcgg aaggagcaaa
    21001 catgcgatga atgagaaaca actagaacaa acgcacgtgg atgaaacgat cgaactaatc
    21061 cagatcgaac aaaatatgct ggatacaaaa caacaagaat tgactcagga aatgaatcat
    21121 tcgacaaaag acacagctaa tcacaagatt cgagctggtt ccaatgaagc tttttatgaa
    21181 tctgctgttg aatatcgcca acatgagcag gaattgcttt tgaaatacca tactcttgaa
    21241 gcacagcaaa aacgcctgca aacgttgtct gtcatgaaag atagtcctta ttttgcccgt
    21301 atcgacttta aagaagaccg tgaaacagaa acattatatc taggtatcgc ttctttaaga
    21361 gatctggcag aagaaacaat cgttattgac tggcgcgcac caattgccaa tctttattat
    21421 gaaggtgaga ttggtcccgc attttatgaa actgaaacag atagaataga tgtcgatctg
    21481 cagttgaaac gacaatttaa aatccaagaa ggacgtattt tatctatggt agatacgtcg
    21541 gaagtaatca atgatgactt tttgctagag atattggatg aatcatcaag caaccatatg
    21601 aaaaacatcg tctctacgat acaaaaagca caaaatgcaa tcattcggga cacaacaagt
    21661 aaagtaatgc tgattgaagg aatcgccgga agtggaaaga catccgcttt gcttcaacgt
    21721 attgcttttc tgttgtatca taatcgcaag tggctcgagg ctgaaaacgt tcttctattt
    21781 tcacccaacc atttgttttc tgattacatc tcgactgtat tgccttcatt aggtgaaagc
    21841 ggcgtgccta cacagacatt caaaaattat ttggtgcagc tgctgccaga gttttcttta
    21901 ctagatgaac agcaacaaga aagtggtttt ttgctagggg aaaaagatcc gatacaagtg
    21961 atgaaaagcg gattgacctt agtcgatcag attgatcgct atatccaagg catcacaaac
    22021 tacggtccct tgttccgtga tatgaaaata aatggccgta cgatcctatc aaaggaatcg
    22081 attcgccaat ggtataaaga aacaaatgaa caattacctt tacatcatag actttctcta
    22141 ttacaaacga agctcctgaa aaaattaggc ggtctgcaaa aagacgaaac acgtcagcaa
    22201 tgggtcaaag atctggcgga agaacagctc caagaactat acgcaacaga tccaaatctt
    22261 gaatatacag aacaaaagga gcgttcatta cgtaaaaaac tggccaacca aatcgtacgt
    22321 aaaagattcc gtcgaatcca tcgagggatc atgaattatc aatttgtcaa tataacgaaa
    22381 caatatctcc actttctaca aactgtgcca ctttctcttc taacacgaca taaaatcagc
    22441 gagaccaggt ggcaggaaca tttgacaact gttcgtacac acttgcgtca aagagaattg
    22501 cgtcaagagg atgctgtact attcttttta ctgatgcgcc gaacatatcc agtgacggtt
    22561 acacacaaag ctcgctatat ctttattgat gaaatgcagg atttcgcacc atcacaagtg
    22621 gcattgctgc aagccttgtt cccaaaagca aatttgactt tctgtggaga tctaaatcaa
    22681 aatgtctttg gaaatgaaac gatcgttgga tcattggaag accttttcgt ggaccgtgaa
    22741 gtcactcgtt tccaattaac gacaagctat cgctccacaa aagaaatcac tgattttgct
    22801 aatcatttta ttgtgaaaga acatcaagta gaaacaacag caagaaaagg agaccttcct
    22861 ttgctcatcc aaggaacaac agatgatatc aaattgaatt ggttagcaga taccattcga
    22921 acgactcagg gaaaagcccg gtattggcgt acagcaatca tagctaaaac acaagaagaa
    22981 tgcgaagctc tttatgctca actgccagac gagttgaaac aacaagtcca gctgatttta
    23041 aatgagagtg actttatgaa gcgttccatt attttacttc cagccttttt agcaaaaggt
    23101 ctggagtttg accgagtttt cttgtgggat gtagatgcag aacatttttc ttctcagcaa
    23161 gacaaattga tcctttacac catgtgtaca cgtgcgatgc atgaattgac cctttttacc
    23221 tccaataatg aaagtccttt gttaaacaat atggatattt catcttatga gaaaaaagta
    23281 ctgtaagtaa aaagacaact gctatcatta atgttagcag ttgtcttttt atttacaata
    23341 ataattgcag aaaaagtaat tcaatcattt aaggtcattt attctatata taaatccaaa
    23401 tctgtttcag gatattttaa tttgacaagc gaaataatca ttttcagttc ttccatgttt
    23461 tctggatatt ctgggtcaaa taccttgcta tgacggccaa tcccgccatt gtcgatcaat
    23521 cggtaaattc gattccattc aatgaattgg tcaattgatt ggaaattgct gattggatag
    23581 ccgccacaat ccaaaatctc tgatacacga aatgctaggt atgcactatc gatcacttta
    23641 ttttttttcg tgtctatctt ctcatttctt tcgataagaa ttttttcagg acgatgtttc
    23701 aagctccact ctaatagtag aaagaaagcc tccatccgat actcttcttc aaataaccga
    23761 aaggctgaat cagaacgacg aaaaagcagc ggaatcagat aattttgtct ataaatcagc
    23821 attggtgcgc ggtccaccat acactctaaa taacggttca gataccctgt accgacatag
    23881 tttcctaatc gatagccttc aacgccgaat cttgcgtatt tttgcgctaa ttttgaacaa
    23941 tcagttacgt tcacagctaa ctcttctact ttgcggtaac cgcttaagat acgttcaaaa
    24001 ggttctaaag tgatttttgc ttccatattc ttccccgtcc atcttccaca tacttcatat
    24061 catttcacat gatacttatg ctctcatcat accacaggtt gaattagaaa agaaaataaa
    24121 tcacacaaaa aagcaagaca atctgttagt gagattgtct tgcttttcga aaaagactga
    24181 atacttttcg ttaaaactgg ttgcttagtc ttctaatgcc acattatgga acacatgctg
    24241 tacatcttct agatcttcca gtgcatcaat cattttttca aatgtttctt gatcttctgg
    24301 agatagtgtt acctcgtttt gagggatcat ttggatctca gcgattgaaa aatcagtgat
    24361 tcctttttct tttaatgctt cttgtatact atggaaatcc gctacttcac cgtaaacgat
    24421 gatttgtcct tcttcttcca ttacatcgcg aacatcgatg tctttttcca ttaggtattc
    24481 aaggatctcg tcagcgtctt ctcctgcaaa agcaaagatt gctgtattgt caaacatgta
    24541 agaaaccgct ccggaaacac ccatgttccc gccatttttc ccaaatgctg cccgtacgtc
    24601 tgctgctgtt cgattcacat tgttcgtcaa tgtatcaaca atcaccattg agccgcttgg
    24661 tccaaatcct tcatagcgca attcagagta tgtttcatct cctgcacctt ttgctttttc
    24721 gattgctcgg tcaataatat gttttggtac attataagtt ttagcgcgat caatgacgaa
    24781 acgtagtttt tggtttgcat gcggatcagg atcacctgat tttgctgccg cgtagatttc
    24841 aatcccaaat tttgcataaa tccggctatt attagcatct ttagcagttt tctttgctac
    24901 gatatttgcc catttacgtc ccatattttc acttcgcttt ctgatttgat agtttcataa
    24961 cgcaaaaacg tcctgttcca ttatacttgt gaatcacgat tctgtgaagc tttttttctt
    25021 tcttccttca ttcttctcat ttttagtcaa ttatctatac tcggattggg atttgcccga
    25081 aattctgttc cggaatattg cctcccaatt gatagatttg atcacttcta actaacagtt
    25141 ccgcttcttg tgcctctttt tttccgattc gggaataaat agaaatctct tttttttctt
    25201 ttaagaatct tcttccagca tcggtaaatc caagtagtcg aagataattt ttattttgtt
    25261 ggacaggaat ctcttgcttt ttgatattca gcaagacata acaagataat cgttggatcc
    25321 gtgtccatgt atatcttttt gtttttacct ttgacacaaa atcctcaaaa ctatcagcag
    25381 ttgcagctgc tgttttcatg cgcgattcta ttccttcggt catctgatag atatctgtca
    25441 gttccagcaa agtagaagat aacaaccgat aacgcaaata cggccaataa gattcccaag
    25501 tctgcagcga acaagttgaa agatcttctt ctgtctgagg cggcacaagt ccagctattc
    25561 tttttccttc ttctaacgca tggcgaatgg ctgttgcact ggctatcctc tgatctgtga
    25621 tgattttttc atgatagcct gcacttttac gtcggatcgg atgtaattcc atagggtgga
    25681 catacttggc attttccttt gcataactta atcccaagat atgatttggc gaagaaaaat
    25741 caagcgtaat atcgggatac agactgcgaa aaacctcagt cattttttgc ggataactat
    25801 acgtttgatc agacagttct tgaaatgcct cttctatcct atcttgattc tcttggacaa
    25861 agcgtccgaa actgctgtaa tcaaacgaag tctcttcttc tgttccaaaa cacaaactgt
    25921 cacagtccag tgtttgcaag atttttactg cacctttagc aaaatagtca gctgactgaa
    25981 ccgcccattc gacgggaagc tccactacta aatccacacc attttgtaaa gcttcattcg
    26041 cgcgatgcca tttatcgatg atagccggtt cgcctctttg caaaaaattc ccgctcatta
    26101 cagcaatgac gacctctgct cctgttattt ttcgtgccat ttccacatga tagcgatgtc
    26161 cattgtgaaa aggattgtac tctacgataa tcccgcagct tttcatgcgc atcctccttc
    26221 atagttatcg ataaaaaaga aatagagaca agtaaaaaaa ggcaaaaatc ggaaaaaata
    26281 cccgaactat ataaactatt ctcgcaaaca caatacttct gcgacgaaaa gctgcactgc
    26341 aagagcaatg cctatatcgt tcggatatat aatttatgtt gaagatttat tcttttcttg
    26401 ttaactcgag caggcaaaac cgctagtctt tgtatgctac aaagaaccag cgctttgatt
    26461 tctctgatgc tgcttcgtct gtaaaatcag aaaatgcttc gactttcgaa aagccgctgt
    26521 tttccagcat tcttaaataa ctttccaatg gataggtacg ctcttgatgt agttcatctt
    26581 cacgaataaa tcgaccagac ccttcttgtt cttcaacgaa aaaggtaaga aaatgttcga
    26641 tgctgtgttt ctcgcttcct ggataactat cccacaaaaa agcaaaatta tccccttgat
    26701 aatgatagct atattctgga aaaacctcat ctacttgata ggtggagtgt acgtcaaata
    26761 aaaatcggcc attttcttct aacgcttgat agacttcatc aaacacttgc tgtacctctt
    26821 gtctattttt catatagcac agcgaatcag aaaaacaggt aattgcctga tattgtccga
    26881 tttctgataa atcgagcata ttgccttcca caaattggat cgatgcgtct tcttcatatg
    26941 ctcgctggct ggcaatcatc aacatctctt ctgaaaggtc taaccctgtc actttatatc
    27001 catcttttgc aaaggcaacc gctaatgctc cagtaccgca tgccagttcc aaaatatttt
    27061 ttgtgtcttc ttgtaaatga cgtttcgaaa aagctaacca ttgctgataa agtgtttcgt
    27121 ccatcacttc atcgtaaatg aaagcaaatg tttcataagc catatgttaa tccaaccatt
    27181 cactaagatc gactagcgga gcatctgacc atagtttttc cagattatag aaatttcgtt
    27241 ctggcgcatg gaaaacatgt acgatcacat ctccaagatc gatcaatacc cattttccgc
    27301 cttcttttcc ttcaatacgt tttacttcat atttgttttc ttcttcttta tcaatgattt
    27361 cttctgtaat tgcgttgatt tgacgttcgc tatttgctga acagatcatg aaataatctg
    27421 ccaacaagga aacatttcga acgtctaaag cgataatgtc ttctgcccgt tttgaatctg
    27481 ctgcttcaat cgcaattttt aattgttctt tactatctat gatgatttcc tcctaatatg
    27541 agcagcttat ttttttgcta cccagtaatt atatgtttcg attgtttttg gataaatctg
    27601 ttgttcttgc gcaagcaaat gggccaatgt atgttttgtt tcaaatgcta cagcttcgtc
    27661 tagatcagcc catgcaatgg ctcgtgcatc ttgtacccca ggaaaatctc gacctggttc
    27721 aatatagtct gctacataaa tgattttgtc aaggagactc atcttagcag ccccagtcgt
    27781 atgcacccgg attgcatgaa gaatctctgc atcggtgatt cctaattccc gctctacaaa
    27841 cgaagcgcca acaagaccat gccagattgc attattataa ttcaataact ccggatcaaa
    27901 accgtctctt acgattacca ttttgaactc ctcatctggt cgttcttttg cataatcatg
    27961 tgtcaatgca gcaatactag ctttttcagg agaagcaccg tattttttgg caagagccac
    28021 ggctgtttct tctactccaa gcacatgctt gaagcgttgt tcgctcattc tcatctgtat
    28081 tttttgcatc aggttttctc tagaataagc agtatattca ttactatagt ccatattcat
    28141 acaacccttc attttgaata taatcaatta ctttatctgg aacaaggtag cggatagaac
    28201 agccttcttt gatcttttga cgtattttcg tggaactgat gtcgatctca ggtacatcta
    28261 cccaaattac aggatatgga gtatccgttg tgtatcctgg tcgacgtata cccacaaagt
    28321 tgaccataga agtcagctca tcgattttat accattttgg caaatattct accatatccc
    28381 caccgataat aaagtaataa tctgtatccg gattgttttg cgtcaattcc ttcatagtat
    28441 cataggtgta acttttccca ccacgagcta attcaatcgt ttcaatctgc aaaaaaggat
    28501 tgtcttccac cgctaattcc aacatgttga gtcgatgttt tgcatcaatc gtctgtttct
    28561 catcaacatg aggtggctga taagaaggca tcaaaaatac gcggtcaaga cctaaattcc
    28621 ggccagcttg ttcagccatc actaaatgtg caaggtgaac gggattgaat gttccgccca
    28681 agatccctac ttgctttttc ttctctaaga attgaggcat ttcttcagga aataattgtg
    28741 aacgaacaaa tgtcttagct tgcgtattca tcatggtcac tccttatatt gcttttactt
    28801 cttttgatag cctttgatac ttttcttttg tggaaggttt gtataataca ataacacgtc
    28861 caatgatttg gacgatttcg caatctattt ctttttctaa tacttgagct gcttcttctg
    28921 caatctcatc tgtattttga agtaacgata ctttgatcag ttctcttttt tctaaagctt
    28981 cttcaatttg aacgatcatt gctgaattga tcccaccttt tccgatttga aaaatcggct
    29041 gaagatgatg cgctttgcta cgtaaaaaac gcttttgttt tcctcttaaa ctcataattt
    29101 tccttcttcc ttaaatcaat gctttgcgtt tcaatacatc tacacccttt ggcgcccagc
    29161 ccgcaattac tactggcgct gttacagtga tccagcctag accggcaaaa acgatgtctg
    29221 ttttttcttt cacagaaaac tcaaaacgaa caagctccgg aaatgcctcg acttcatcag
    29281 gacgaggagg ctgtaataat ccacctacat gtttttgata aaattcgtct gctttttcca
    29341 gtttcgttcg atgaatattt acatcatttg acacataagc aataaatgaa gcacgattgc
    29401 cgctgataaa atcaaatctt gcaagtccgc ccaagaaaag tgtttgccct tcattcagct
    29461 gataaacttt aggtttgatt tcttttaacg gtgcaatgat ccgcaaatct tttttaccta
    29521 agtagtgcgc catttgatgg cgatggataa ttcccggtgt atcaatcaaa aaatgcccgt
    29581 catctaaagg aatctcgatt ttatccaagg tcgttcctgg aaactgcgaa gttgtgatta
    29641 catcttgtac tcccgctgta tttttgatga tttgattgat aagcgtcgat tttccgacat
    29701 ttgttactcc gacgatatag acatcccgtc catcgcggta ttcttcgatt ttttctaata
    29761 gttccgtcat ctcatgagat ttcttagcac tagttaataa tacatctact ggacgaattc
    29821 ctgcttcgta agcacgttcc ttcatccatt gtgttaattt agtttttttc aatgatttag
    29881 gtaatatatc cactttgttc ccaactaaaa gtactggatt gtcaccgaca aaacggtgta
    29941 gtcctgggat tagtgaacca ttgaagtcaa aaatatccac cacattgacg atcaatgcat
    30001 ctttttgccc taattcattc agtaagcgca aaaagtcgtc atccgtcaat gagacatctt
    30061 gggtctcatt ataatggcgt aatctgaaac aacgctgaca atagacttcc ccggaagcta
    30121 aacctttttc caaagccgtt tgcggcgtgt atcctaattc accgggtttg tttgtttgta
    30181 taacggcacc acagccgata cattgtaatt cttctgtcat tcgattccac ctcgccagcc
    30241 catatcaggg tgttttgcta atagataggc cataattctt ttttcccaaa aacgattaaa
    30301 ttgtgtcttc caactatctg ttgcgataat gggttttaca aggatgctac gtatccctgc
    30361 acgattggct ccacgtatat cagtcataat ctgatcgcct accattacta tctcatcatc
    30421 tgctaaatcc aattgtttct ttgctatgtt gatccctctt gctaaaggtt tcattgctcg
    30481 tgcaacatac aaaagatcaa atttttcaat cgctcgcgcg acacgttttg aattattgtt
    30541 tgaaacaaca acaacaggga ttcctgcatt tttcatttct aaaatccaag taagcaactc
    30601 ttctgttcca tctggattat tccatgcaat caacgtattg tctaaatcgg tcaatactgc
    30661 tttgatgcct agattcttta attgggcagg tgtaatctga tagatggctt ctaccatcca
    30721 tgttggtttg taatttgaaa acatgctgtc tcctcatctg caaaaaatga aggagcacat
    30781 aaagtactcc tcaaccccgt attatactgc atatcagcaa aaaaaactac ctctatactc
    30841 gttcgtcttt cagaaaaagc atttctttac aaaatgacca aaaataaaga ttgatcacag
    30901 aaaaatttag aaacaaaaaa caactaatat tggcggaacc tcttgtatcg tttttccagt
    30961 aatttatgct gatctaatcg aacaagttcc gtcaatcttt caatcaacgc ttttttcata
    31021 atgtgtgcga ctttatatcg tggcaactgc tcgccgttga acgtttcagg aataactcga
    31081 tcaacgattc ctaactcgcg tagttctggc gcagtaattt tcatcaactc agctgcttct
    31141 gcggcgcgac taccgtcttt ccacaaaatc gacgcaaatc cttctggaga aagcacagca
    31201 taaatcgttt cttccagcat ccagacttca tccgctaaac ctagagcaag ggcaccgcca
    31261 cttccacctt caccaatgat gatggcgatg atcggtacct ttaaatcaga catttcgagc
    31321 agatttctgg caatagcctc tccttcgccg cgctcttctg ctcctacacc gcaatatgca
    31381 cctgctgtat tgatcaaggt aatcaccggt ctattgaact tttccgcttg tttcatcagt
    31441 cgtaaagctt ttcgatagcc ttcaggatgg ggagaaccaa aatttctgcg gatattttcc
    31501 tgcagatccc gtcctttttg aataccgatc actgttaccg gtttgccatc taatcgagcg
    31561 attccaccaa caatcgcttc gtcatctgca aataaacgat caccatggca ttcctcgaaa
    31621 gaatcgaaga tctcttcaaa aaaatccaag cttgtccatc gttctttagc tcttgctaac
    31681 tgaacgacat catgtgctgt cttatccacg atctatccat cctttctgtg tatgcaattc
    31741 aagaagcgta tggattttct gtttcaattc catgcgggga acaatctgat cgacaaaacc
    31801 atgagataat aagaattcag ccttttggaa atcttctgga agttcctgct tgatcgtctg
    31861 ttcgatgacg cgtcttccag caaaaccgat caagctttgg ggttctgcta gaataatatc
    31921 gccttccatt gcaaaactgg cagttactcc tccggtcgtc gggtccgtta aaacagttag
    31981 ataaaaaaga ccttcattgc tatgccgttt gacagcagca gagatttttg ccatctgcat
    32041 tagagaaaag attccttctt gcatccgtgc gccacctgaa gctgtgaaca agacgactgg
    32101 aagactttcc tttgttgctc gttcgaataa tctggtgatc ttttctccga caatcgttcc
    32161 catacttccc atgataaaat taggatccat cactccaata atgaagggaa tcccctgaat
    32221 ggctgcttta ccagtgagga ctgcttcatg aagtcctgtt ttatcttgca tttttttaat
    32281 tttttccgta tattcgggaa atgctagcgg atctttggtt acaagatccg tatcccattc
    32341 ttcaaaactt ttttcatcaa taatcaaagc tagacgctgc catgcaccga ttcgaaaagc
    32401 gtatccgcaa tgagggcata ctttttcttc accgatgtct ttcgtataaa ggatatgttt
    32461 gcaatttgga cactttgccc acatgttatc aggaacagat ggcgagttag caggtttgct
    32521 ctctctatta ggattgatcc gaatatattt ctttttctta aacagagcca tctatgcgcc
    32581 tcctatctcc gtttctggtg tccaattcgg taaaaattct tcttgtaaaa atgctgtgct
    32641 gtaatcacct gctatgactg caggatgact aatcaaatcc atctgaaatt ctgcgttcgt
    32701 gatgattcct tctgtgataa attcacttaa ggctcgctgc atcttcatta atgcttcaaa
    32761 acgcgtattt ccatggacga ttatttttgc aatcattgaa tcataatatg gcgggatcgt
    32821 atatcccggg taaactgcac tgtctactcg cagtcccatc ccacctgctg gaagcagtaa
    32881 gttttggatc ttccctggag aaggagcaaa atggaaagca ggattttctg cattaatccg
    32941 gcattcgatt gcgtgtcctt ggaatactac ttcttcttga cacacattca aaggctcacc
    33001 ggctgctatc tccacctgtt tttttactaa atcgattcct gtgaccattt ctgttactgg
    33061 atgttccact tggattcgag tattcatttc catgaaataa aaatcgcctt cttcatccat
    33121 cagaaactcg atcgttccgg cattttcata attgactgct ttagctgctc gaacagcagc
    33181 gtctcctagt gcttctcttt ttgtttgtga gatcactaca gaaggagatt cttccagtac
    33241 tttttgattg ttgcgttgta aagaacaatc tcgctcgcct aaatgaatga catgaccaaa
    33301 tcgatcacct aagatctgaa cttctatatg gcgagcagga taaatgattt tttccaaata
    33361 catatcatca tttccaaatg ccgctgctgc ttcttgctga gctgaagaaa aatgctgtgg
    33421 gagctcttct tttgattgaa ctttccgaat gcctttcccg ccaccacctg cagctgcttt
    33481 cagcatcact ggataaccaa ttctgtctgc tatttccaat gcttcttcta ctgtagataa
    33541 tacaccagta cttcctggaa tgactgggac atttgcttct tgcatcaatt gacgcgcatt
    33601 gatcttattt cccattgcat cgatcgttgc acttttagga ccaataaatg tgatattgca
    33661 ctcttcacac atggaggcaa atcggctatt ttcagataaa aaaccaaatc ctggatgaat
    33721 tgcttcggct tttgtcacga ttgcagcgct cagtacttcc tgaacattca gatatgaatc
    33781 aacggctttt gccgggccaa tgcagattgc ttcatctgct aactgtgtat gaagtgcttc
    33841 ggcatctgct tctgaatata tcgctacggt ttggatccct agttcgcggc atgcacgaat
    33901 gatacgtaca gcgatttcac cgcggttagc tatcaatact ttagaaaaca tatttcacct
    33961 atccaatcat aaaggttaat tccgcttcgg ctactttttt accgtctact ttagcgattc
    34021 ctttgcctat tccggctgaa gctttcactt tcaatatctc aacttcaagg tataaggtat
    34081 ctcccggtgt aactttctta cggaattttg ctttgtccaa tccgccgaaa taagccgtct
    34141 ttcccttgaa ttgttcaaga gaaagtaatg caactgctcc tgcttgagcc attgcttcaa
    34201 caatcaatac ccctggcata acaggttctt ctggaaaatg tccttgaaaa aagggctcat
    34261 tgatcgttac atttttctta gcaacgatcc gttctccttc aaccatttct tccactcgat
    34321 caatcaaaag cattggataa cgatgtggaa tgatttcttt tatttcttgt atgttcattg
    34381 ttttccctct ttcctgcttt gcttattttt gctgaatcct aaagagtggc tgtccatatt
    34441 cgacaactga ctcgttttct acaaggattt ctgtgatcac tccgtcggcc tcactagtta
    34501 tctcattcat cagtttcatc gcttcaataa tgcagataac ttctcctttg gcaacttgat
    34561 cacctacttt tttgaaagct ggtttgtcgg gcgctggttg cagataaacg attcccacga
    34621 ttggcgaaac aacctcgatt ccatcaaata ctgccgattc tttttctttc attatttctg
    34681 gagcagttgt tgcttgttca ggtatgacat tgactggctc cgaaactggc aacgtttcgt
    34741 ttgtttgaac catattcatg cctcgacttg ttttattttt attcatatac aattcaaatt
    34801 gaccttcacg caaatcgaat tccgttagcg aggattgatc aaattgactg actaattctc
    34861 tgatttcatt gatatccaaa attattcctc ccagcgtttc atgcacagaa ccgcattatg
    34921 tccgccaaac cctaatgaat tactcattgc ataagtaaaa cttgcaggtt tgctttcgtt
    34981 tttgacaact gtcaagtcaa tctcaggatc ttgtttttct acattgatcg taggtgggat
    35041 aaattgatgt tctaatgcca gcaaagttgc caaggcttcg atcccgccgg ctgctcccaa
    35101 taaatgtcca gtcatcgatt tcgtgctgct gacgtaagta tctctgaaat tttcacctaa
    35161 tgcgatttgg attgcttttg cttctgcctg gtcattggct ggtgtacttg ttccgtgagc
    35221 attgatatat ccgacttgtt ccggctgtac accagcttct tccatcgcaa gcttcattgc
    35281 tttagatgca ccagaaccat ctggagtagg agctgtcata tggtaagcgt cacagtttgc
    35341 accgtatcca acgatttctc catagatttt ggcaccgcga gcttgtgcat gttctaaaga
    35401 ttcaagaact agaacgcctg ctccttcacc catcacaaaa ccattccgat tttcgtcaaa
    35461 cggaatcgaa ccacgattag gatcagttga ttctgagagt gctgttaaag ctgcaaatcc
    35521 agcaatcccc atctcacaaa tcgttgcttc tgttcctcca gcaagaatga catcagaata
    35581 gccatgtttg atgttacgga atgcttcccc aattgaattc gttccgctag cacaagctgt
    35641 tacgatagct gtacaaatac cttttgcacc tacacgcaaa gcaatatttc cagctgccat
    35701 gttggcaatc gccattggta cgaacattgg agaaactcgt tttgcacctt tttcatgtag
    35761 acgaataact tggttttcga ttgttggaag accaccgatc ccagatccga tgatgacgcc
    35821 aaaccggtct tgattcattt tttctttatc taaaccgctc atctccattg cttctaaagc
    35881 agcgtagatt ccatagatcg aaaacatatc cattcgtttg ctatcttttt taataaaata
    35941 tttatcgtaa gggaaatctt tgacttcacc cgctaaggta atccctgttt ctgaagcatc
    36001 aaatttagtg atcggtgcga tgccattcgt cccctctttt aagctattca aaaagctgtc
    36061 tgcgtcattt ccaataggtg aagtgactcc atagccagta attaccactc gattcatttg
    36121 tttgctctcc ttttcttatc cgtgcatgac caatccgcca tcgacattga tgacttgtcc
    36181 ggtgatatat ggattttgtg ctaagaaaac tgctgtttgt gcaatatctt ctacttgtcc
    36241 gaaacgctgc atcggaattt gcttttccgc ttgttccttg actttgtctg ctaaaacttc
    36301 cgtcatatca gttgtgatga atcctggcgc aatggcatta catgtaatgc ctctagttgc
    36361 agcttctcgt gccacagatt ttgttaatcc tactacgcca gctttactag ctgcataatt
    36421 tgcttgacca atatttccaa tcaacccaga tacactagag agattaatga tggccccttc
    36481 tcgctgcttc atcatttttt tcaatacgtg ctgcgtcata ttgaaggttc caatcaaatt
    36541 gatatccaga cattttttga aatcttctgc atccattcgc atcacaagtt tgtcatttgt
    36601 gattccggca ttgtttacta acacatggat cgatccaagc ttttcttctg cttctttgat
    36661 catttgtccc gctttctcat aatcagagat gtcaccggaa actcctacgc attttacacc
    36721 gaatgcttcg atttcttcta tcttttcttt tggaatctct ccgcgaccat tcaaaatgat
    36781 atttgctcca gcttttgcaa aagctaaggc catcgctttg ccgattcctc ttgtactacc
    36841 tgtgataaat acattttttc cttttacatc cataacgttc ctccttatag tattgctatt
    36901 gtttcatcaa atgtctgctt attctcaaca cgcagaactg gtattgtttt atcgattttt
    36961 ttcataaatc cgcttaatac ttttccgggg ccgacttcga tgacttgttc gatgccgatt
    37021 gtttttaact tatggatact ctcatagaaa cgaacaggtt gcatgacttg ctgttcaagt
    37081 agtcccgcga ttgtttcttt cttcattatt tccgttgttg tgttgcttat gataggaaaa
    37141 gaaggttcag agaattgaat ctgacttagg tccttcgcca gtttttttgc tgccggttct
    37201 aaaatagctg tatgaaaagg cccgctgaca tttagaggga tcattctttt gaaccctttt
    37261 tcttttaata gtaaaacagc ttcgtctact gctttttctt cgccaccaat cacgatctgc
    37321 tgaggtgtat tataatttgc aggagatacg atgccgtact tgctagcttc atgacagctt
    37381 tcctcgatcg tttcaatcgg cgcattcatc actgcaacca ttttcccgct tccagctggg
    37441 gcagcttctg tcatataagc gcctcttttt gctactaacg caactgcttc agtgaaggat
    37501 agcgcattac tagctactaa tgccgaatat tctcctaaac tcagtcctaa agctgcatct
    37561 gggatgattc catgctcctt caataagcga taatacgcga tgctgactgt tagaatagct
    37621 ggctgtgtat attgcgtctg atccaaacgt tcattttctg taaagcaaag ttcagccata
    37681 tcgtagccga gaatctcact tgcttcatca aatgtctgct ttacaacggc ttcttcatat
    37741 aaatcttttc ccataccttg atattgtgca ccttggccac taaataagaa tgctgttttc
    37801 atgtttttct ccaatatatc cagaatatat gtttgattct tcctattcaa aaaggccgag
    37861 acattcctat ttcaggaaat gtcccagccc ccaacctaat tttaatgatt atgcagtttg
    37921 tttttctacg taagtcacta aatcttgaac cgttttgatt ccgtcttctg tttcgatttt
    37981 cacgtcaaat tcatcttcaa tttcattgat gatttggaat aaatccaagc tgtcagcttc
    38041 taagtcttct tggatgtcag tagtcaattt gatttcttca gtttcttttc ctaattcttc
    38101 tgcgatgatt tcttgaattt tttcgaatac cataataata tattcctccg atattgtttg
    38161 ctttttattt ttataattta acagtctaca actccatgag aatacttccc catgttaaac
    38221 ctccgccata gcctgtaaat attactttct gctgttttcc taaggtgatc tttccactag
    38281 aaactgcttc atccaataag atagggatgc ttgcagcaga tgtattccca tatttatcca
    38341 tattggtcag gaacttttct tgcggcatct ttacttttcg ggcaattttc tcaataattc
    38401 tgaggtttgc ctgatgcaaa agcagataat caactggttt gtctttcatg acttcttgga
    38461 tattgtttgc aacgtctcgt acggcaaaat caaaaatatc tctgccagtc atttgcaaat
    38521 aatacgaacc ttctgaatct tctgaataga acggattttt attttgctgg tagccagcgg
    38581 tcaatgagct acttctggta ccgtcagctg ctaatttttc tttcagcaat tttttctgtg
    38641 gattcgcttc taagagaatc ccacctgctc catcgccaaa caacacagca gtcgtacgat
    38701 cagaccaatc gattagctta gatagtgttt caccaccaat caccagtccc ttagttgagc
    38761 cgcagcggat cattttttca gccatgctta acgcataaac aaatcctgag cacgcagcac
    38821 tgatatcaaa agcgatagca tgagttgctc ccaatttccc ttgtacttgt gctgctacag
    38881 atggtgtcgt gtaatcgggc gacattgttg ctactaaaat aaaatccaaa tctttagggt
    38941 ttagattttt ctgttttatc aatttttccg ccactaaaat gcataaatca gaagtctcct
    39001 gatttgttac acatcttcgt tcacgaatac ccgtccttga cgaaatccat tcatcagagg
    39061 tatccatcat cttggaaaga tcattattag taataatctt ttcaggaagg acgctggctg
    39121 ttgcagtaat cattccaaat tgttccatta aatatcctca cttatagtct tgcaagaagt
    39181 cgtgcaagtt tttcagtgca tccagcaagg catgctgttc ctccgtagcc attccgtcta
    39241 agatgttctt gaccatttca cgatgaaaat gctgatggac ccgaaatagt aactttcctt
    39301 ttttcgttag tcccaacttt acaacgcggc ggtcatcttc actgcggata cgttcgacat
    39361 agcctttttt tactaacttg ttaatagcag tggtcaaggt cccaacagta attgatagtt
    39421 ctttggctac ttctgaagtt gtttttttct tgtacatccc gattgcctcg atcgtgtgca
    39481 tctctgtgat tgacagatct ttgaattgag attttttcag ctcagactct tcgattgtca
    39541 aaatatcatt gaagacacta acaagataat catttactgt ttttaaatct ggttccatgt
    39601 tccaccgtcc actaattagt ttgattatca aatcttttga tgttcaaact atatcttaac
    39661 ttttttcaaa atgcaacctt aaaagatcat ttttttacta tatgagcttt ttttaagatt
    39721 ttactcattt aaaacaactg ataaatcagc atttataatt tcttttatta gaaaaatcat
    39781 ctatctcaca tattttgatt atcaaagtat tttctgtgaa cagaactata gaattcccta
    39841 aaacttgtcc attatttcaa aatttgttat agtcttttta ttcaaagcgt aaaaggagat
    39901 cctatgttaa aagaaaaaat gaaaactctc cccatgctgc cgggtgtcta tcttatgaaa
    39961 gaccgagatg gtaaggtcat ctatgttggt aaagcaaaac ggctcaaaaa tagagtaagc
    40021 agctattttc atcagaataa acagcattca aaaaaagtat tacgtatgat tcatcatata
    40081 acagattttg atttcgtcgt agtagacacg gaattagatg ctttattgct cgagtgtcaa
    40141 ttgatccaac attaccgtcc tttttataac cgacaaatga attatttcag taattataat
    40201 tatgtacata ttaccaataa gggatttgta ttaacagata ctcctacggc tcgaacatac
    40261 gggccttttc gtctctataa aaaaatgccg tctattttgc gtataatgga agaaacttat
    40321 caaatgcctt ggttgtctga aattagtttg ttagctttgc gagtccagct tcctgaccta
    40381 caggaaatga cttttgaaca gaaaaaaaag gaactccaag ggctgtttca aggccgaaat
    40441 aaaaagctac tgacttactt gaaaaaaaga caacaacatt tcatctatca gttgaatttc
    40501 gaaaaagccg gtatgcttca aaaagatatc gaattagtta cttattttat tagacggatc
    40561 caggaacaaa agcagttttt aagaacacca tcgctcacct tcagcatgcc attagcagca
    40621 gatgagagtc agaaaaagca ctacctcgtt tgttatggtc aacttgcaga aacaatgatt
    40681 acctctggtg acgtttctcc tgacttctat tatgaaaaga aagaagctca tttatctttg
    40741 aaacgtcaat tgtcaaaaga agaaatcgat cctgtacaaa tcttgatcag ttaccgcaaa
    40801 aaattagaaa aagaacagtt tgaaattgaa ctgttaaaca aaaaagaagc tgaaaagcaa
    40861 ctaaattagt tgcttctcgg cttcttttag gcatcttcaa cttcaaatgt caattatcct
    40921 aaaatttatt ggattaagtc atagatttcc atcgctacga tatcgatatt atcaaattcg
    40981 tattgctgat gagtatctgt ttcagttaat tcaaatgtat cggtcgcttt atcataagtt
    41041 actgtacact tctctacgcc ttctttttca aaacggcgaa cttgcagttc attatctgct
    41101 gactcgacca tagcctccag tcgttttatg attgcgacta attgtgaatg tgtcatcgga
    41161 ggtcctcctt ttcttatttc tgttatattg tatcaaaagc atagcctact tgcattgatt
    41221 ttctctaaaa aaactcgttt tttatgattt tttttctggt atttttcctt caggccacca
    41281 aagtttgatc aaagcttggg ttccgtcatt ctcaaaacct ttatctgcca actcttcata
    41341 tagtttcaat gcttgggtag ttgctggcaa tacaagatcc attttttctg cttcttctaa
    41401 tgcaatcttt aaatctttga taaaatgttt gacaaaaaaa ccaggtgtgt aatcttcttt
    41461 taaaatacga ggagaataat tgcttaaaga ccagttagct gcacttccac ctgaaagcgt
    41521 ctcaatcact ttctttaaat caagtccgtt tttttgtgca tagacaagca tttccgtcat
    41581 tcctgtcatc gtacctgcaa tcatgatctg attagccatt tttgtatgct gacctttccc
    41641 agcagaacca tgcaatgtaa atgtcgtacc aaattctttg aataaaggca gtacttgatc
    41701 ataaacggct tcttctccac cgaccatgat cgtcagtgta ccattctttg ctcctaagtc
    41761 accaccggat accggtgcat ctaacgcatc tgcgcctttt tcttttgctg tttttgcaat
    41821 tttttctgcc aggcttggtg tacttgtagt caaatcaact aaaatatgtc ctgagatatc
    41881 tgcagaaaaa atccccgact gtccatagta gatttcttct acatctttgg ggtaacctac
    41941 cattgtaaag agaatattac tttgttctgc taccgctttt ggtgtatctg cccagatagc
    42001 tccttctgtt actaaaggat cagcttttgc ttttgtccga ttatagacag ctacttcgtg
    42061 tcctgcttct agtagatggc gtgcgacagc acttcccatg acgcctgttc cgataaaacc
    42121 aagtttcatt ttttcgacct cctaaaaatc aaaaatcctt gcttctatgc tagtatacgc
    42181 tagaaacaag gattttttca taaaaaatgt ttgaatttta tcttttaaat gaatttaatt
    42241 ttattttgat tcgttcaatc gagtcttctt cttcttttct tcgcatctct tcttcatgat
    42301 aaacaaccat gtcttgataa aattcgatca tagcttcgcc gaaatgtgta gatgaaatat
    42361 cataaagttt agcttctaaa acttttggat ctttaggaac ttcactggaa atataatcaa
    42421 taagtgctgg tgcaaagtct tcgtcggttt caaaagtttt ccctaatgaa ggatgatcga
    42481 acaatcggtt caaataagca tttccttcca cgacacaagg tgttccggct gccatcgctt
    42541 ctgtataagt aagcccttgt gtttctgaag tagaagcact gacaaaataa tctgccgctt
    42601 tataataaag tgctacatca ttgttgtcca cttctcctgt gaactgcaca aattcttcta
    42661 actgcagttc tgagatcaat tcctctaact cttctacata aggtcctttt cctacgataa
    42721 ctaatctggc gttaggataa gcggagatga cctgaggaaa cccattaatc aaggcttgga
    42781 tatttttctc ataagaaatc ctgcttaaag aaagaatcat caaatggttt tcctgaagac
    42841 ctagtgactc ccttaatttg ctgatatcct gctgagtgat atcagaacgt ttgaattttt
    42901 caatgtcgat accagtagga atcacgcgaa gcggtgctat tacaccatag ctgcgtaatg
    42961 tatcaataac acgttcactt ggacaaacta cacctgtcgt atgatttgca aataatctag
    43021 acaagtattt tacatgggat tgcctgatca cttttccttt accgatataa tgaaggtagt
    43081 cttcatacat cgtatggtaa gtatggatca gaggtatttt caacttctta gctaccatct
    43141 tcccaagtat ccctgctccg aattctgtat gggtatgaat aagatctagt tctagttctt
    43201 tggcaaccaa ataagcatac cacatgcctc taacaacaac tcttcgatcc ttgaaagaaa
    43261 taaatggtac acttggcatt cgaatcacat ctttttccaa cttatccgca ttaggatcgg
    43321 tcgttgtaaa aatatagact tcatgcccat gtctttctaa ttcttgtttt aatgttttga
    43381 tcgatgtagc aactccgctg acttgcggaa agtaggtatc ggtaaaaaag ccgattttca
    43441 tgtttttcgc ctccaaacta gtccttgacc tgatttactt tttttaattt gctagagact
    43501 ttttcattca gtacactttc gtatacattt ttaagttctt caccgatttt attgatactt
    43561 cgctcttttg ctgtttgata accggcttgt gtcgtactcg gtagttcttg attggtaatc
    43621 tgttggatca gtcggataaa ttcttcgttt gtcttcccca tatagcagtt cttgctatct
    43681 tctaaccagc cattatacac tggaatatct cgaacaagta cgttttgttt gcttgctaaa
    43741 gcttctaaaa caacgatccc ttctgtctct tcataagaag ggaaaaagaa tagatctgca
    43801 cctgaatacg caccttctat gatctctcca cgaatgtaac caggaaacag gacattttca
    43861 ggatgatctt cttttacaat tttccggatg ttccgaggaa tcgagtacat gggaacatga
    43921 ccaaaccaaa taaatgtgta ttcgggcatc ttcttagcaa tttctacgaa atcaatgatt
    43981 cctttacgtt cgaaaaacaa accgacacaa atgattactt tttgatccgg agacagtttg
    44041 aaatattctc tgaacttttg ttctttcatt ggatcagggt gatatttctc taagtcgatc
    44101 ccattggaaa tagcttgaat cggcacacgg ataccatagc tttccaacaa ctgttttgaa
    44161 taaggtgttg gcgtgatcag atagtccgct ttttggtaca atcctaccag atattttttt
    44221 acgataggag aaagctggtt cgatccgata aaggaatttc ggaaatcttc ctctgtagaa
    44281 tgcgcatgat agacaacttt ttttccttct cttctggctt tattgaccat attatgacta
    44341 ttgattccgt atgtattgat gtgcaggatg tcataatctt ctttttcatc tagtgtataa
    44401 gagataccga cttccgtcag agcacgtttt tgatgatcaa gcgcacgccc gattccagat
    44461 tttgcaagca tcttttcact ttcaaaatat aataatacct tcaccttacg tcccccttca
    44521 cttatatagt ataacatagc ctacaaactg tcactcaaac ttaagcccta tttttgtcta
    44581 ttcttactga caaaaacgtt ttcttaaaaa agaacaaaaa aactggcgta gctcttttac
    44641 aagccacacc agcttttgat acgttgttta ttttacatat tcatgaacaa gttcaacgac
    44701 ttcttccatc gtatcgcatt ctttcaatgc acgatcagca agttcagcca ttttcgctgt
    44761 gtccaagcgt ttcattaaac tacgcgtttt aagaatagat gtcgcactca ttgagaactc
    44821 atctagaccc atacctacta gcaatggaac agctgtttga tctccagcca tttctccaca
    44881 catacctgcc cattttcctt cagcgtgtgc tgcatcaatt acatttttga tcaaacgtaa
    44941 aattgatggg ttatatggtt ggtacaagta agaaacgcgt tcgttcatac ggtctgctgc
    45001 cattgtgtat tgaatcaaat cgttcgtacc tacagagaag aaatctactt cttttgcaaa
    45061 cttgtctgct aagactgctg ctgctggaat ctcgatcatg atgccgactt ggatcgtatc
    45121 agatacttcc ttgccttcac ttatcaattt ttgtttttct tcttcaaaga tcgcttttgc
    45181 tgcgcggaat tctttgagtg tagctaccat agggaacatg atacgtaaat taccatgaac
    45241 agatgcacga agcaatgcac gcatttgtgt acggaacatt tcgtcgcctt gttcagataa
    45301 actgatacgc aatgcacgat atcctaagaa tggattcatt tcatgaggta attgcagata
    45361 tggtagttct ttatctccac cgatgtccat tgtacgaaca actacaggtt ttccttccat
    45421 accttctaat acagctttgt aagcttcata ttggtcatct tctgttggga agtctggaga
    45481 atccatatac aggaattcag tacggtacag accaactgct tctccaccat tattatggac
    45541 accaactaga tcttttggtg ttccgatgtt tgcagctaat tcaaaatgct tgccgtcagc
    45601 tgtgacagtt tctgcatttt ttaatttttc ccattctgct ttttgtgctg cgtaatctgc
    45661 acctgctttt tcaaattcag ctttttgttc atctgtagga tcgatgatta catcgccttc
    45721 gatcccgttg acagccaaaa tatcgccttc tttgacttta gcagtaattt cttttgtccc
    45781 aacgattgct ggaatttcta aagaacgtgc catgatagca gaatgtgaag tacgtccacc
    45841 aatgtctgtt acaaacgctt ttacaaaatt gcgatctaat tgtgctgtat cacttggagt
    45901 caagtcatgt gcaacaacga ccacttcttc gttgatcatt gatggatttg gtaaagtaac
    45961 gcctaataag tgcgctaaaa tacgtttagc aacgtcacga atatctgcag cacgctcttg
    46021 catataagca ttatcttcca ttgcttcgaa cataccgata tacatatccg ttacttcttt
    46081 tagcgctgat tcagcattta cgctgttgtc tttaatattt tgcttgattt gacctaccat
    46141 ttctggatct gaaagaacca tcaaatgggc atcaaatact tgcgcttctg cttcacctaa
    46201 gctttgcgct gctttttcac gaatttgctg caattcttca gtagatttag ctaatgcagc
    46261 atccaaacga gcttcttcag ccgcagtatc ttctactgtt gccttactga atgttaaatc
    46321 cggttgaact agcaggtaag cttttgcaac ggctacaccg tcactagcgg caatcccttt
    46381 tagcatttca accattattc agataagcct tctttcttca ttgtttcaac gattgctgcc
    46441 attgcatcag cttcgtcagc accttctgca gtaatagtaa catcagaacc ttgacctaca
    46501 cctaaagaca taacgcccat gattgatttc aagtttactg atttaccttt atactctaag
    46561 tttacatcag agttaaattt gcttgctgtt tgtactaata gtgtagctgg acgagcgtgg
    46621 atcccagttt ctgctactac gtgaaattct ttcttttcca tattaatcgg tctcctttaa
    46681 gtgagtgttg tttttatgtg agggttttct tttttagtaa ttcagagaat cctaacaaat
    46741 gccacccttt catctgtaaa gattaacatt ttttttcgtt agatacaaca gttttcattc
    46801 aatttcagat aaaagtattc aaattattcc ggattctttt tcatcctttt cttcacattt
    46861 tataacaaac gtgtttattt cctttttctt gtcgctttct cttctcctga cgtttatcat
    46921 tctttccttt gaccctcttt gttttcatat gaaacgaatt acttgcttcc ctttttattt
    46981 ttagtataat aagagtcaaa ggtcaggaat ggtcaataga gatttcacct tttctacctc
    47041 ataaatctct taaaaaacta ggggttattc ttttacctca tgaaaaacga gatgtaaaat
    47101 atggatgtac ccatttttgt gaaaggacgt gaatgattca tgctttgtca aaactgcggc
    47161 aagaatgagg caacgattca cttgtatgcc actgtcaatg gtcagcggac acaactcgat
    47221 tactgtcaga gctgttatca aaaaatcaaa aatcaacaaa atggaggtct gactaatatg
    47281 gcccaaaatg atccatttgg atttggcagt ttggacgatc ttttccgttc catgtctcgc
    47341 caaatgcaac agcaaggaaa ttatgagcaa acaccaccaa cacaatttgg cggaaacaac
    47401 aacttcaatg gtggtcagcc acctcaaggc aatacagaag gtttattggg agaatacgga
    47461 atcaatatca cagaacaagc acgacaaggt gatatcgatc ctgtgatcgg acgcgatgac
    47521 gaaatcaaac gagtcattga aattttaaat cgccgaacca agaacaatcc tgtcttgatt
    47581 ggagaaccag gtgttggtaa aacagcagtt gttgaaggtt tagcacaaaa aatcgtagat
    47641 ggtgatgtac cgcaaaaatt aatggacaaa gaagtcattc gtttagatgt cgtatcttta
    47701 gtccaaggta ctggtatacg aggacaattt gaagaacgta tgcaaaaatt gattgaagag
    47761 atccgtcaag cagaaaatgt gatcctattc atagatgaag ttcacgaaat agtcggtgct
    47821 ggttctgctg gtgatggaaa tatggatgct ggtaatattt taaaaccagc tttagctcga
    47881 ggagaattgc aaatggttgg tgctactacc ttaaatgagt accgcatcat cgaaaaagac
    47941 gctgctttag aacgtcgtat gcaacctgta cgggtagatg aaccaactgt cgaagaaacg
    48001 atcagtattt tgaaaggttt gcaaaaacgt tatgaagact atcatcatgt aaaatatact
    48061 gatgaggcca tcgaagcagc cgcaacttta tccaatcgtt acgtccaaga tcgcttcttg
    48121 ccggataaag ccatcgattt gctagatgaa acaggttcta agaaaaactt gacgatccaa
    48181 atcgttgatc ctaaaacaat cgagaaaaaa ctgcaagaag cagaagaaca aaaagtttta
    48241 gcttctcgag aagaagattt cgaaaaagca gcttattatc gcgatcagat caataaactt
    48301 caaaaaatga aagaacgtca gctcactgaa gaggaaacac ctgtgattac cgaaaaagat
    48361 atggaaaaaa tcgttgaaca acggacaggt attccagtgg gtgaattaaa agaaaaagaa
    48421 cagacacaac tgaaaaactt agcagatgac ttgaaagctc atgtcatcgg acaagataac
    48481 gctgtagatc gagtagcgaa agcgattcgc cgaaaccgtg ttggattaaa caaacagaat
    48541 cgtccaatcg gctccttctt atttgttgga ccaactggtg taggtaaaac agagcttgcg
    48601 aaacaacttg cctacgaact attcggttca caagattcaa tgattcgttt cgatatgtct
    48661 gaatatatgg aaaaacatag tgtctctaaa ttgattggtt ctcctccagg ttatgtcgga
    48721 tacgaagaag ctggtcaatt aacagaaaaa gtacggagaa atccttacag tcttgtcttg
    48781 ttagatgaag tagaaaaagc tcatccagat gttttgcata tgttcttgca aatcttagat
    48841 gatggtcgat tgacagatgc acaaggaaga acggtcagct ttaaagatac gatcatcatt
    48901 atgacaagta atgccggaac tggtaaagta gaagcaaacg ttggttttgg tgcggcacgc
    48961 gaaggtgtta ctcgttctgt attgaaccaa ttaaacaact actttacacc agaatttctg
    49021 aaccgttttg acgggatcat cgaattcagt gcattatcaa aagaaaactt gatgacaatc
    49081 gtcacactaa tgctagacga tgtcaaccaa atgctggcag cacagcaact tcacatcgaa
    49141 gttcctacga atgtcaaaga aaaattagtt gacttaggct atgatccatc tatgggtgct
    49201 cgtcctcttc gacgcacgat ccaagaacaa atcgaagatg gtatcgctga attttatctt
    49261 gatcaccctt ctatccatga gttgaaagca aaactggata aagatggaaa aatcatcgtt
    49321 acttctaaac cagaacgttt ggctaaagaa tcagccgaag aaacggctga ataaatccag
    49381 ttttatagcg tgagacggta tttctttgag aaatgccgtc tcattctttt ttcagaaaag
    49441 tcaaaatact gttcatttta taaaaaagaa attataataa gagaaacaag caattaaaaa
    49501 tacataaaag aggtgagcgc catgaaattg gtaaatgtaa caaacagcca ttcccgtctt
    49561 gtattaaacc agcttgaaaa cactgatgcc catctagtca aggtctacac agccggaaat
    49621 accactattg tctacactga agcccctgaa cataatgaaa ttctgctgat caatgacaaa
    49681 cgtaaaatcc agccgaaaga aatcgaagat gctaaaaatt atttcttaga taaaatcaaa
    49741 gacgccgttt accacgagga tgaaatcaaa gtaatcgaat tggcaggcct tgttgaaatc
    49801 tcgattccaa aacatgaatt aggcgctaca ttagccgtgt aaacaaattt tgaacataat
    49861 aattaaagag cgtgggacaa aagtaaa
//
LOCUS       DAFBSV010000008        47571 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.008, whole genome shotgun sequence.
ACCESSION   DAFBSV010000008 DAFBSV010000000
VERSION     DAFBSV010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47571
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.008"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            336..1439
                     /locus_tag="LLB18_000503"
     CDS             336..1439
                     /locus_tag="LLB18_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBK5243533.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGAYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            1723..2403
                     /locus_tag="LLB18_000504"
     CDS             1723..2403
                     /locus_tag="LLB18_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBK5243534.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            2493..3527
                     /locus_tag="LLB18_000505"
     CDS             2493..3527
                     /locus_tag="LLB18_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBK5243535.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            3541..3876
                     /locus_tag="LLB18_000506"
     CDS             3541..3876
                     /locus_tag="LLB18_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243536.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPVPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEEKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            3860..6322
                     /locus_tag="LLB18_000507"
     CDS             3860..6322
                     /locus_tag="LLB18_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243537.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLADIIAIITRGIPLQFDVTANVAKMTENGDKYDTSPN
                     KILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGGNLNPGA
                     YAFSASAEINTWNSYISTSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLTMGLTEG
                     RFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQGGLLSP
                     VALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIHYRLYSK
                     GTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTNMYPSFA
                     YKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQENVTFT
                     LTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLSKIGDTI
                     HLTYNYQLNTVDTSVQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTILVPKQEL
                     TLVNVPDDFTFGNDLPKPLKTSYYEAKGDFSFDVRDTRLPSTSPWQLTGTLTSLFKND
                     QGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLLEVNSST
                     NAQPGATYQGMVTWELTAGPTS"
     gene            6378..7937
                     /locus_tag="LLB18_000508"
     CDS             6378..7937
                     /locus_tag="LLB18_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5243538.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            7934..9298
                     /locus_tag="LLB18_000509"
     CDS             7934..9298
                     /locus_tag="LLB18_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBK5243539.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            9469..10539
                     /locus_tag="LLB18_000510"
     CDS             9469..10539
                     /locus_tag="LLB18_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5243540.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            10554..11222
                     /locus_tag="LLB18_000511"
     CDS             10554..11222
                     /locus_tag="LLB18_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5243541.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            11242..11820
                     /locus_tag="LLB18_000512"
     CDS             11242..11820
                     /locus_tag="LLB18_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK5243542.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            12223..13134
                     /locus_tag="LLB18_000513"
     CDS             12223..13134
                     /locus_tag="LLB18_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBK5243543.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(13390..14307)
                     /locus_tag="LLB18_000514"
     CDS             complement(13390..14307)
                     /locus_tag="LLB18_000514"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HBK5243544.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            14509..14946
                     /gene="zapA"
                     /locus_tag="LLB18_000515"
     CDS             14509..14946
                     /gene="zapA"
                     /locus_tag="LLB18_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBK5243545.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            15004..15552
                     /locus_tag="LLB18_000516"
     CDS             15004..15552
                     /locus_tag="LLB18_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HBK5243546.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            15667..18027
                     /locus_tag="LLB18_000517"
     CDS             15667..18027
                     /locus_tag="LLB18_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBK5243547.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            18114..18428
                     /gene="trxA"
                     /locus_tag="LLB18_000518"
     CDS             18114..18428
                     /gene="trxA"
                     /locus_tag="LLB18_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBK5243548.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            18610..20388
                     /gene="uvrC"
                     /locus_tag="LLB18_000519"
     CDS             18610..20388
                     /gene="uvrC"
                     /locus_tag="LLB18_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBK5243549.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            20533..21432
                     /locus_tag="LLB18_000520"
     CDS             20533..21432
                     /locus_tag="LLB18_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5243550.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            21425..22687
                     /locus_tag="LLB18_000521"
     CDS             21425..22687
                     /locus_tag="LLB18_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5243551.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            22848..24746
                     /locus_tag="LLB18_000522"
     CDS             22848..24746
                     /locus_tag="LLB18_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HBK5243552.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(25045..25764)
                     /locus_tag="LLB18_000523"
     CDS             complement(25045..25764)
                     /locus_tag="LLB18_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBK5243553.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     gene            26101..26433
                     /locus_tag="LLB18_000524"
     CDS             26101..26433
                     /locus_tag="LLB18_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243554.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            26420..28423
                     /locus_tag="LLB18_000525"
     CDS             26420..28423
                     /locus_tag="LLB18_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBK5243555.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            28442..28912
                     /locus_tag="LLB18_000526"
     CDS             28442..28912
                     /locus_tag="LLB18_000526"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBK5243556.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            28933..29517
                     /locus_tag="LLB18_000527"
     CDS             28933..29517
                     /locus_tag="LLB18_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HBK5243557.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            29532..30518
                     /locus_tag="LLB18_000528"
     CDS             29532..30518
                     /locus_tag="LLB18_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HBK5243558.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            30508..30819
                     /locus_tag="LLB18_000529"
     CDS             30508..30819
                     /locus_tag="LLB18_000529"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBK5243559.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            30841..32622
                     /locus_tag="LLB18_000530"
     CDS             30841..32622
                     /locus_tag="LLB18_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBK5243560.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            32615..33991
                     /locus_tag="LLB18_000531"
     CDS             32615..33991
                     /locus_tag="LLB18_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBK5243561.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            33998..34633
                     /locus_tag="LLB18_000532"
     CDS             33998..34633
                     /locus_tag="LLB18_000532"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBK5243562.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            34663..36018
                     /locus_tag="LLB18_000533"
     CDS             34663..36018
                     /locus_tag="LLB18_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HBK5243563.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKFAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKITIHSKIALTVTGTLLLGGFVVFFFTERNGETLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(36210..37604)
                     /locus_tag="LLB18_000534"
     CDS             complement(36210..37604)
                     /locus_tag="LLB18_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBK5243564.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQKLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQNKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            37696..38667
                     /locus_tag="LLB18_000535"
     CDS             37696..38667
                     /locus_tag="LLB18_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBK5243565.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKDKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSATLTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            38664..39445
                     /locus_tag="LLB18_000536"
                     /pseudo
     CDS             38664..39445
                     /locus_tag="LLB18_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
     gene            complement(39614..39985)
                     /locus_tag="LLB18_000537"
     CDS             complement(39614..39985)
                     /locus_tag="LLB18_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBK5243566.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TTPSYYFVIDPDGYKIEVIRG"
     gene            40119..40562
                     /locus_tag="LLB18_000538"
     CDS             40119..40562
                     /locus_tag="LLB18_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBK5243567.1"
                     /translation="MDKPIFGEKKQSANYQTRYAAYIVIERDKRIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(40605..41414)
                     /gene="yidA"
                     /locus_tag="LLB18_000539"
     CDS             complement(40605..41414)
                     /gene="yidA"
                     /locus_tag="LLB18_000539"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBK5243568.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(41433..42800)
                     /locus_tag="LLB18_000540"
     CDS             complement(41433..42800)
                     /locus_tag="LLB18_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBK5243569.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHKVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(42784..43614)
                     /locus_tag="LLB18_000541"
     CDS             complement(42784..43614)
                     /locus_tag="LLB18_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBK5243570.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            43777..44214
                     /locus_tag="LLB18_000542"
     CDS             43777..44214
                     /locus_tag="LLB18_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBK5243571.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            44290..44910
                     /locus_tag="LLB18_000543"
     CDS             44290..44910
                     /locus_tag="LLB18_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HBK5243572.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     EKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            45099..45605
                     /locus_tag="LLB18_000544"
     CDS             45099..45605
                     /locus_tag="LLB18_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HBK5243573.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            45622..46521
                     /locus_tag="LLB18_000545"
     CDS             45622..46521
                     /locus_tag="LLB18_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBK5243574.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKARR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            46608..47493
                     /locus_tag="LLB18_000546"
                     /pseudo
     CDS             46608..47493
                     /locus_tag="LLB18_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
BASE COUNT        15682 a         8199 c        10071 g        13619 t
ORIGIN      
        1 atcgagaggt tgtgaaaaag tcgcttagtt tcgagtagta agaaaaattt tgtgaaaatg
       61 gctttccaca tttttgcata aatttgactt aataccgaga aaatggcttt tgaacaccgt
      121 ttattcaaaa aaagggactt tgacactact tttgtcaaag tcccatcggt tttttatcta
      181 tttttattac aatcatttct tccagagtag tgacatctgg aatggctgaa atgtaaacag
      241 attatttgcc tgtatcaatg tcgaagagta atataaaaag tgtaaacgct atcatattgt
      301 tcatcattca aattttatag agagaaggca ttgagatgga aaaaacatat caagcaggta
      361 caaatgaagg aatagtagat tttatcaata tggaagattt agaaatcgcg gcttcacaag
      421 tgattccagc tggtgcttat ggttacatca gcagtggtgc tggcgactta tttacttatc
      481 aagaaaatga acgggcattc aatcatcgtt tgattattcc tcatgtatta agagatgtag
      541 aattacccga tacaactaca cattttgacg aagaaatgct gactgcacca atcatcatgg
      601 caccagttgc tgctcatgga ttagctcatg tgaaggcgga gaaagcttct gcaaaaggtg
      661 tagcagattt tgggacgatc tatacagcaa gttcttacgc ttcttgtact ttagaagaga
      721 taagagaagc aggcggggag aaagcaccgc aatggtttca attttatatg agcaaagata
      781 atggaatcaa tttggatatt cttgaagtgg ccaagcgtaa tggagcaaaa gcaatcgtat
      841 tgacagcgga tgcaacagtt ggcggaaacc gtgaaacaga ccgcagaaac gggtttacct
      901 tcccgctgcc aatgccgatc gttcaggctt atcaatcagg agtaggccaa acgatggatg
      961 ctgtatataa atcttccaaa caaaaactta gtccaaaaga tgtagaattt atcgctgctc
     1021 attctgattt gccagtctac gtgaaaggtg ttcaatcaga agaagatgtc tatcgatcat
     1081 tagaatctgg tgctggtgga atttgggtat ctaaccatgg tggccgtcaa ttagatgggg
     1141 ggcctgctgc gtttgattcg ttgcaatatg tggcagaagc agtagataaa cgtgtaccaa
     1201 tcgtgtttga cagcggtgta cgacgtggac aacatgtttt caaagcaatc gcatcaggtg
     1261 ccgatcttgt tgctattggc agacccgtta tttatggatt gtctttagga ggaagtacag
     1321 gagtccatca agtgtttgat ttctttaaaa cagaattgga aatggtcatg caattagctg
     1381 gaacacaaac agtagaagat atcaaaaaaa taaaattgcg tgagaatcgt tttatttaag
     1441 aaataaatga cgaaaaaaat aggagtgcgg cagatgatgc cgtactccta tttttatagt
     1501 tcaaggatgt cactaataga ataatttgaa acgaaaaaat aaaattgaaa tattgtttca
     1561 tacttaataa aaaaggaaga atattcatgt aaacgatttt attgtttttt tctcttttat
     1621 acaaaaaggg tcataatttc aagtaagcgg atgaattcat gaggattttt tgcatactgt
     1681 ctctactata cttaggtcac taagaaaaag gagtgattta ttatgaaaaa gaacatgatt
     1741 gggacattat tactttcaac acttcttcta ggcggcttgg caacaccagc ttttgctgag
     1801 ggtcaagcga cttcaaaagg agatattacc tttactgaac caacaaatac cgttgagcct
     1861 cttaacccta ctgatccttc aaaaccagta gagccagcag atccggaaaa tccagcaact
     1921 ggccagacag gttctttaac attggatgta gttcctgaat tgccatttgg tacacacgag
     1981 attgaaagcg gaacaaaaac gtatcaagta gacgcttcaa aaaacgatac accttatctc
     2041 caagtatcag atcgtcgagg tgtaggtgca gatggccaag cacaagggtg gaacgtgaca
     2101 gtttcggttt cagattttgt aaacggttca caagttttgc aaggcgctga attagatttt
     2161 ggaacatcca ctgttaaaag tacgtcagat aacgaatcca ctggaccaac tagtcaaact
     2221 gtaactgggt tgagtaaagc aagtgcagcg acaccaatat ttacagcagc aaaagatcaa
     2281 ggtctgggaa catggctttc tgtttatgat ccagcaaata tcacactgaa agtgccgaaa
     2341 gcagcagctg gaacattcac ggctgatttg acttggaacc tcgtggctgg cccagtagca
     2401 tagagtatga aataaattca acaaactgcg gtgaaaatac tataggtgaa ggatttttta
     2461 ccgcagttgt tgttgaaagg atgtggtgga caatgaatca aagtaaacga ctgtttgttt
     2521 cgtttttttc tattttaagt ctatttttca tttttccgtc aatcagccaa gcaaaggatt
     2581 cagcaggaga ctttggaatc aaaccggtat ttccagagaa ccaaatagat aaagcaatcg
     2641 gttattttga tttattagtg gcaccggaac aaaatcagac actagaagta attatcagca
     2701 attcttcaga tgaagaacga acatttgagg tctctgtcaa tccggcggta acgagtgatg
     2761 gtggaacgat cgattatagt caaaaaaacc caacgttaga tgagacattg ccgtttgatg
     2821 tccgtgacgt tttgctcatt gcgaaaaagg aaatcaatgt atcagcacat gcagaaacaa
     2881 ctatacctat agaagtgaaa atcccagcaa aaagctttaa gggacgtgta ttagcgggta
     2941 ttcatgtttc acctaaagaa gaagctgaaa cagaaaatgc tacagaagga gcacaaatca
     3001 aaaatcgtat tgcttataat ctcgcagtcg ttttacaaga aagtcaagag acgatagaac
     3061 cggatctgaa acttttatca ggagatttgg acgaggtcaa cgcaaagcca actgttcagc
     3121 ttcgtttcca aaatcctcag cctaggatta tcagcaattt gatatttacg agcaagatct
     3181 tttatgaaaa tcagctttat attgaaaata cgtctaatga atttttagtt gcaccaaatt
     3241 cgaattttca cttgaatctt gatttagctg gtgataaagc aaaagccggc gattaccgcg
     3301 cagaaatcat agcaaaatca ggcgacagta atgaatggcg atttacacaa aactttacga
     3361 tcaaaaaaga aaaagcacaa aaagtaaatg aaaattccgt ttttgcagta caagaacaat
     3421 ctttcccatg gctttatgca ggattggttg ctgcagttct agtgttatgg ttgattttgc
     3481 tgtttttgtg ggtccacaag aaaaagaaaa aaggagaaac aacatgatga ggtgatttcg
     3541 ttgaaaacat cgatcttatt gggagggatt attgcaagtt tgctgttctt cagctggcaa
     3601 gagccagtcc aagcagatac caaaagttca ggtacgatta cattttatga tctaagtcca
     3661 gttccgcatc caagtggttc agtcaatggc gcatcaaaac agcagacaca gctaccgatt
     3721 tataaagaat ctaatcaaca tggcgtattc ccggagacga atgaagaaaa gatccgtttt
     3781 ctttatttga tcattggtat agaattatgg cttcttgcgt ggttgttgtt atggagaaga
     3841 aaggaaaagg aggatgaaca tgttgctaca aaataaattt tcattttttc gctccttctt
     3901 ttttacttcg ctttttgttt taagtatatt tatcttttca ccttcggcag aagctgttgg
     3961 agcaacgcct cctgccattt cttatgatcc atacacgtat gaaaatatcg tacctccaaa
     4021 tggtggacgt agtgcagtca atggcgggaa gcttgtccaa ctaactgggg ctaaccaatt
     4081 gcctaaattg actgctactt atttgaacga tggttcaaat gatccttgga aaggtggcac
     4141 ggtccgtttt cattgggaaa gccatgtgaa actaacaaat gtacttgatt tggtgaatat
     4201 cactgcacaa ggatttgcat ttgtggcgat catcaatttg ccggaacatg tatcaagcag
     4261 tgatgtatta aaagcaattg actggaacaa cgcctacttg tatattgccg gtgcccccat
     4321 caaggttact agcggtagtt tattatcagc aggaagccat accttgcgtt ttgggatggg
     4381 gtcgtgggat acaaatactc tattggcaga tattattgct attattacgc gaggtatccc
     4441 gcttcaattt gatgttacag ctaatgtcgc gaagatgaca gaaaacggag ataaatatga
     4501 tacgagtcca aacaaaattt tgaccaaggg taaattacaa ccttctatgt ctaaaaaggc
     4561 cgttttttct gttgattttt atgattcgaa taatattatc caagatcgta tgttcaattc
     4621 gattttagct ccagctgcag gtagatttta tcctaaatta actggcggaa acttgaatcc
     4681 aggagcatat gcattttctg caagtgcaga gataaatacg tggaatagtt acatctcaac
     4741 aagtgattca acaggaaaat ataatacatt tgctgatacc acagaatacg tggatggaaa
     4801 taaccagaac cttccaggct ctaccaatag tcggacattg acgatggggc tgactgaagg
     4861 acgttttgat cagttgccat ttagtcgctt tgatcgcgta gtcaactatt ttacaggaaa
     4921 aaacgttaca caaggagcaa tactgactca tactccagca agcacaagtg gattgaatca
     4981 gacagccaat atcgtgtaca gtgggaaaga tgcgcaaggc ggattgcttt ctcctgttgc
     5041 tttaaaggta ttggagcagt acaagctaga cggaacggtt ttaccaacaa acttaacagc
     5101 cgatagtcag tggggaaagc tcctttcttc tgcatcgtac caagtcacgg ccaattggtc
     5161 agcaactgaa ctaaaaaagg gttcgatcca ttacaggctt tattcgaaag gaacccaaaa
     5221 attagcgaca ggatggacag atcaactttt ccaaacgatc caatcaaata acgggggtgt
     5281 aaatacagct acttctacac tacctgcatt ggcttcaggg caatattatt ttgattatcg
     5341 cttggtggac gatgtactta ctaacatgta tccgtctttt gcgtacaaat ggcagtctga
     5401 acaagctgga atcaccactc ttcctcaaat aacagtggct aattttccat ctgtgagtgc
     5461 agatagtcag ctaaaaaacc ttagcagaca acctgagaca ggagatcccc tgtctgctct
     5521 atcaggagat acgattcaag aaaatgtgac attcacgtta acaaaatctg gggatgcgat
     5581 aaccgacaaa aaaatcacga tctcacttcc tgaaaatact acttatatca atggttcctt
     5641 aaaattaaat ggtacaacta tcgcagatac cggcattcaa caaggagttt ctgtcccagc
     5701 agatctattg agcaaaatag gagataccat tcatcttact tacaactatc aattaaatac
     5761 tgtagatact tctgtacaat ccgtcagcat actgacaaag gcagctgtac tttccagcaa
     5821 tattacatta gcagatggtg ctaagcttcc taacccagtt gtccaaacat ctgctaaaac
     5881 aattcttgtc cccaaacaag aattaacatt agttaatgta ccagatgatt ttacatttgg
     5941 taacgatctc cccaaaccgt tgaagacaag ttattatgaa gcaaaaggcg atttttcttt
     6001 tgatgtgcgg gatactcggc ttccaagcac gtctccttgg caactgacag ggacattgac
     6061 ttctttattt aagaatgatc aaggtcaaga attaagcgga acaaaattat acttcaatca
     6121 ttctggatca aaacaattga ttcagcaagg tcaaaacacg ttgatttatg agagtgatgg
     6181 aacagctaaa ggagaggttc tcgttgactt tcccgatacc gatggtttac tcttagaggt
     6241 aaatagcagt acgaatgctc aacctggcgc aacgtatcaa ggcatggtca catgggaact
     6301 gacagctggg ccaaccagct aagtgattag aatttgtatg gatctgtgat aactgtcaca
     6361 gatcctcttt ttcaaggatg agaaggaaac ttctgctgtt aaaatcagaa atgcttggag
     6421 gagtggactt ggaacttttc agtttgcttg aaaaaaatga acaacggcaa atcaaacttt
     6481 tccaactttt attagaggaa aaaggagaga tttccgttaa taacgtactt acccgcttat
     6541 cagttgatcg ggctaccttg aaagaagatc tgttttattt acaagctaac ttggaaaata
     6601 tcaaacaatt ggaaattgtt atccaagaag ggaatatttt attaatcaga catggaaata
     6661 tagcagcagt cgatgtttat tatcattgct acttgcgcta ttctacaaaa tatcagatac
     6721 ttctttatct gttggaaaat ggctcatttg atcggcagaa acttgtcatg gaacttaata
     6781 tcagttcggc tactttgtct cgcagagtga aggaattaaa tgattcttta aatgagtttc
     6841 atctgaaaat aaaaagcggg cggctgaccg gtccagaaag tcaaatttgt tatttttatt
     6901 tccaattatt ttggtttgga cgtccttatc ttgaaaacaa aaaagaatac agtgatttat
     6961 caggaaacac ttttttagat ctgctgcaaa aagagtttag ttttactatt acagaagaag
     7021 gacgattgaa atttgaaata tggctttcca ttatgaagaa gcgaatgcgc tgtacgaaaa
     7081 aatccaaacc agattatagc aatcttcctg ttggattgtt tcaaacgaca caatttttat
     7141 tggacctcca tacatttttg acccgttact tctttcaata tgcctttcct tggaatcaaa
     7201 atgaaacgtt ggttttttat cttttcatga tcagtaactt tacattagat acacataact
     7261 cgcatgtcca ggagtttttg ataagcgaaa aatacaaaga cgacgtagta gctcaattga
     7321 atcgaacgtt taaacaatcg atagaagaat atttctcttt ttatgttttt ccagaagaga
     7381 tttcgcaaaa gattgcgttg acagtgatgc aaaatcacgc tcattttgcc tattttagag
     7441 gatggatgaa tatttttggc caagaaggat taaaacagcg gttaactgaa gtagaagata
     7501 aacaattcct ggttttatgt gaaagattgg tcagacaaac atttgctatt gttgatttta
     7561 ctgaagtaga cgaggaaaat gcccgctttg aattatttgc tcgctatgca tctattttgc
     7621 ggacgctgat caagcagtta gaattacgtc tgcaaattgc ttatgatctt ccttatgaaa
     7681 ggctaatggc ggatatcgtg aaagaaatca tccaggaaca attgctgaat acgatcaaat
     7741 atgatttagt cgaatacgag aaagaaaagc agtatgatat cattttgact agccaattga
     7801 aagagtaccc gtcacagaag tccgctaaag tttttgtatt cactagcaac gaatataatt
     7861 atgatttccc ctatttgaac caatttttaa aagaatgtta tttagaaaaa ttgaatttaa
     7921 ggatgaataa aacatgaaaa tcgtgatcat tggtgcttcc catgcaggca tcacagctgc
     7981 cctaaatcta agaaaacttc aaccgaaagc agaagtttta ctgatcgatg aagatcataa
     8041 agatggacta ggctatgttt caaatggaat caacctttat ttaaaaggaa agatacgtag
     8101 tttagctgaa gttgcccata acatgcggac tcttcaagaa agtggggcaa aactgatcac
     8161 cgaatggaga gtaactgaac ttgatccaga caaacatcag ctcatcctcg catccaaaga
     8221 aggaaaaaac gagaccataa cctatgataa attaatcgta gcaacaggtt cctctcctgt
     8281 caccttgtat aaacaaattg aagctgaaaa tgtctacacc tataaaaatc tagtgcaatc
     8341 taagcaagta cttgccgctt taaaagaagc aaaagaagta gtgatcttcg gtgctggtta
     8401 tattggattg gaattagcag atgctttgag aaataaagga tacattattc atctagttga
     8461 ttatatgccg aatgttttat caagatattt cgataaggat atgatcaaca gttttcaaaa
     8521 tcagctgcaa actaagcaaa tcaattttta tccaaatgaa ttcttgatcg attggaaaaa
     8581 atcagaagag aaagtagtat ccgtacaact tctatctcaa gcaataaagg cagatatggt
     8641 cattttttct gcccaaactc gtcctaatac gacattgtta aaagaaaaag tggctttgta
     8701 tgaggatgag actgtgatag tcaatgaata tctgcagaca agtgatccgg acatctatgc
     8761 gattggagat atcgtcccag tcagttttga caaaaataaa cggcatctct ttttaccttt
     8821 agttactcga gctgtacata tggcaagagc agtagcgcta actttgagtg gtcagccaac
     8881 cgcttacgac ctcagacaaa agataacagc agcagtcatt atagactact ttttaggaac
     8941 tgtagggctg acagaagatg aagcgccatt cttggaacaa aataccggtt cgtgttcagg
     9001 agaatttgat ctatttccac aatacgatga agaaaacaaa acagtaaatg caaagctgat
     9061 ctaccatccg gatacattag aaataattgg cggacagctg ataagccaag aattcttatt
     9121 atcagatttg aacctgcttg cggatatcgt gaaacacaaa actacgattc cacagctagc
     9181 agttgaggat tttggatttc tgtctgaaca cacctctcgt tttcactacc tcaatgagtt
     9241 agcttttaaa gtactagcta agagagcaaa tagcaataga gtagataaaa gactgtgaga
     9301 aatatcacgg tcttttattg tgtggggata taataaatat taatcaatcg agaataaaaa
     9361 attcatataa tgaaatagcg gaagaatttt ttgagcataa tattcgccaa aaatttatca
     9421 agtgataaaa ttgttgtata aaatgattat ttcaggagga ggagttaaat gtttttagca
     9481 ttaaatgaaa ttatgcattc aaagttacgt tatgcgttag ttgcaggggt gatgtttttg
     9541 atcgcctacc tggtattttt tttgactggg ttagcttatg gcttagctca agataatcga
     9601 acagcagtcg acaagtggga ggcagattcg attgtgcttt cgaaagatgc aaattcaaat
     9661 ctagggatgt ccatgattac taagaagata gcagaagaag tcgaaggtgg gaaagtggcg
     9721 tatcttgccc agacacctgg agtcgtgact agtaaagaca gtacagaaga aggaaaaatc
     9781 aatgttagct tcttcggtat cgataaaaat caattcatca tgcccaatct tgttgaagga
     9841 aaagcttttg ataacgatga tgaggcagta ggcgatatta gtttgaaaga agaatatggt
     9901 ctagccgtag gagatacagt taagttatct ggtagtgaca agacgtttaa actaactggc
     9961 tttacggatc atgccaaatt caatgtctca ccagttctct atacaaccat caatgcttac
    10021 caagagatcc gcttcgaaaa agaagataca agtgaaaatg cacggattaa cgcaatagtt
    10081 gtcagaggta aaatcagtaa tttacctgaa gatttagaac agatcaaaat ttctaaattc
    10141 atcaatgaat tacctggata taatgcgcaa gtattgactt ttggatttat gatcggattt
    10201 ttgatcgtta ttgcggctat tgtgatcggg attttcattt atgtactgac gatgcaaaag
    10261 attaatatct ttggtgtaat gaaagcacaa gggatcacag gaggatttat tgcgcgttct
    10321 gtagtggcac aaacattcat tttatcattt gttggtattc ttcttggtct attaggaaca
    10381 gtgggaacat cccttgttct acctgatgcg gttccattcc aaagcaattg gctgtttttt
    10441 ggcgtcatta gcttgttgat gctggtagta gctgtgttag gcgcactatt ttctgttcgg
    10501 acaatcgtaa aaatcgatcc gttgaaggca attggataag aaggaggaag agcatgaaag
    10561 caatagaatt taaagaagta gaaaaaagtt tccaagatgg cgaccaagta gttaaagcat
    10621 tgaaagaaac aaccatgagt atcgataaag gggaatttgt tgcaatcatc ggtccttctg
    10681 gttcaggtaa aagtactttt ttgactttgg caggcggatt gcagacgcct agcagtggct
    10741 ctgtatttat caatgatcaa gaattcagta atcaaaaaga aagtgaacgc gttaaactac
    10801 gttttaaaga aattggcttt attttgcaag cttccaatct ggttcctttt ctgacagtaa
    10861 aaaagcagtt attattagta gataagatca aacatgaaca tcgtcaaaaa gaagcaaaag
    10921 aattatttga gcagcttggc gtggataagt tgatcaacaa gtatccagaa gaactatctg
    10981 gtggagaacg gcaaagggtc gcaatcgctc gtgcattgta caatgatccg tccattattc
    11041 tagcagatga accaactgct agtttggatt cagaaaaggc acgagaagta gtcgatatct
    11101 tggcaaaaga atcaaaagac aaaaataaag caacgatcat ggttactcac gatacacggc
    11161 tgattgacaa atgcgataga atatttatga tggaagatgg tgtattgaaa gaaaaagaat
    11221 aaccaaaaag caggtggaaa aatggtccat cgatacaaca aagatacaca gcaaaaaatt
    11281 ttgaaagaag cgactgactt gtttatgtcc aagggatatc tcggcacttc aacaagagag
    11341 atcgcacaaa aagttgggat cacccaaccc aatctctatc attatttcgg tgataaagaa
    11401 aaactatata cggcagtttt agaaaaccac ttaaaagatg ttggaaaagc tttgagagaa
    11461 atcgttcaaa caagcgaaac gggatttcaa gtaaccttga caaaaatggc gcagtttttg
    11521 attgagacac atctggtcga tttgtttctg atgcttcacg atcttgaaag caatctttca
    11581 aaggaaacaa gagatcatct tttctttcta tggaagaaaa attatcgtga accttttgaa
    11641 gaaatctttt cagcaaacca atctgtgcta agaaatggga tttcaaaaga aatcgcagca
    11701 aggcattttt tcttagtgtt agcaccttac atcactcggt cgaaaagacc tgtggaagaa
    11761 ccgctaaatg tggcgcaatt gatcgattta tatttgaatg gtgtattagg agaagcgtaa
    11821 agctgttata tagggagaaa aatagttagg tgaagaagca agatatgacg aagatcgtta
    11881 tatcttgttt tttttatata ggtagttttt cataaataca aatttgttat tctctcatga
    11941 ttatcagggt atatttttat ttattatgtc ggtgttccag gaagtgtttt aatttaataa
    12001 cgaagaaatt aattgtttgt agaatgaagg aaactattta ttgggtagat gaatcaccac
    12061 gaatagtcaa aaggagattt caggatatgc caaaaatgaa aaaaatcatt ttagcagtaa
    12121 tgttattttc tacggttata tcttttacag cccctttttt gcgtacttaa gctgatttta
    12181 agttttgacc cttagtctgg atctacgagg tgagagtcaa gaatgaaaaa aataattgga
    12241 gcttttgtat ttgcaatcat tatcattatt atctgttttc aaatagatgt ttttggtcaa
    12301 aaaaagatag ttggacaaac ggtcagcagt acgaacagta cggttacaaa gacaaaggaa
    12361 tcatttgatg atacagaaca agagacatta atcaaaatcg gaaaaaatga ccgtacacta
    12421 tatacagatg actcgctaac taccccactt gcaactataa acggcggaga gctggcggag
    12481 tttctttctg aaacaaaaaa tgcttatcag atcaagacaa atgatggcta tactggatat
    12541 ttagccctcg aagatggaac caaagtcaca aagaatatac aaacaaaacc ggaagagcta
    12601 tctgatgcag tgattgtatt agatcctggg catggcggaa atgatactgg ggcattaagc
    12661 aatgatgaac aaacagaaga aaaagatata acattaagta cagccataaa agtaaaaaag
    12721 gcgctagagg atgctggagc aacggtttat ttgacccata ctacagatga attagtacag
    12781 cttggagata tatgcgacta cagtgaagaa aaaaaggcag atgtctttat cagtttacac
    12841 gcagactcta cggaatatgc gaatgaagca actggaatca cgacatatta ttactatgga
    12901 caagaggaaa cattagcaca gacaattgct gactccttca ctgatctgcc tctggattca
    12961 agaggaatct ccactgggaa ctatcaagtt cttcgagaaa atcttcaacc ttctatttta
    13021 atcgagatgg gttatatgaa taatgatagt gatttaaagg aattagtaac agacagttat
    13081 cagcagcaga ttgctgcaag tttgacacaa gcattgacca cttattttca gtaataaata
    13141 agcccagcca aacaaaaata gctcctcata tttttcgttt ggccgggctt attatcgcag
    13201 atgcaagctt ttgaacaccg tttaaggaag aggttgtgag cctgccgttt aactccgcgt
    13261 cacaaggagc aatttcaaaa aacagcttct catgtttgat gactattgtg acttgtgacc
    13321 gaggagttgg catgagaaca ccgtttattc ggaacaaggg actgtgacat gacttttgtc
    13381 acagttccat tattttttta gcagcttcaa agctttttct gtattggcaa aatgaagttt
    13441 ggcatatttt tcaagcatag gcatgccgcc tttctccaat agttttgccg ctacttggtc
    13501 agatttcgtt ccagctcctg atggaagggt gattccagct tcagctgatg ctttgtgtaa
    13561 ctcttccaaa aagctggcac gactgatgat agaagcagca gcaacagcta aatgatattg
    13621 ttctccttta gtaacgaagt acagtttttc ttgtaattga tttttttcta aacgcgcata
    13681 ttttttaaaa tttgcttccg gcgtaaactg atcgatcaaa atcgcttctg gtttttctgg
    13741 ctcgattttt tttagcagca aatggatcgc ttgattgtgc aaagcgactt tcatccgaac
    13801 ggcattgtat tttggttgga tctcattgta tttttctgga gataagacaa gcagtttata
    13861 ggggatggtt ttttttaaga tgtcagcaag ctggatgatt tggctatctt ttaactcttt
    13921 tgaatctcta acaccaagtt tacgtaattc tgcaagctga tcacgtttca cataagcagc
    13981 acatactgtt agcggaccaa aatagctgcc atttccgacc tcatcactac ctaaaacgga
    14041 taattgactg atattttttg gcaaagaaga ggctgttttt gctggcttgg cttgtttatc
    14101 ctgtgcctcc ccccatttat cagcttctat tgctgcattc gtaccttgaa acatcacttt
    14161 tccggatgta taagcggtaa tggtcgtccc gtcttttttt gcagcaaagc tagtataagg
    14221 aatctgttta tttaacaaat aagagcgata gtatgctttc atttgactaa gttggtcgtt
    14281 tgttgctttg ataatgacgt tgctcataaa attctcctcg tttttataca taaaactata
    14341 ccgcaactca cgacttttcg ttttctaaga gattgcgaga catagcattt ttttaaagtt
    14401 tatcatataa tagttaagta tgtgaaaaat atttgtggag aacggtgaaa gaaccaactt
    14461 catggtacac taaataaaac tttcatcaaa taggaggaaa tgattcgtat ggcgcacgaa
    14521 aaaacacgct acaaagcagt gattgccaac caaacatata ctattatcgg acgggaaacc
    14581 aagcatcata tggatatcgt aacgaagctg atcaatgaac agttagcaga attgaaacaa
    14641 ttatcaccac aaatggataa tgaacaagca gcaatcttga tggctgtcaa tgcgctttcg
    14701 gatcaattga agaaacaaga aagaatcttg gagctggaag aagaaacagc agaattaaag
    14761 aaaaaaatga tcaaatttac agagcttgaa aatcgtgtga aacgcattga agcaatcgag
    14821 aacgaagctc gggaagtatt gaaagaaaat ggtcaagcag atcataccat taaaaatcat
    14881 gtggaagcac aacagatttt aaacgagaaa cgaaaaggac aaattaaaca aaaatcttct
    14941 aattaagatc cttttatcaa aataagaaaa atttaaaaaa gttagaagag aaaggaacgt
    15001 agcatgctga gtttgctgat tttattttta ttgctaattg cgtttttttc tggagcacgt
    15061 cgcgggtttg ctttgcaaat catattcgcg attggatatg tattgtcatt tattgctgcc
    15121 cagcattttt acaaaccatt agcaagtcat ttggaattat acattccata cccagctgtc
    15181 accccaacat caaagttagc attttttgat caggtatttg cttttcacct agatgaagct
    15241 ttttatgcag gaactgcttt tctgattatt ttgctaattg gctggctgct tacccgattt
    15301 gtgggggttt ttgtccatgg attgacgtat gtgccgatct tgagacaggt agactggatt
    15361 gcaggaggca tcctgtcact aatcatggct tacgttacta tatttttgat tttgcagtta
    15421 cttgcctttg ttccattaga tgtggtccaa aatcaattcg gcgagcatag tttcgctcgt
    15481 tttatcgttg agagaacgcc atttcttacc aacaagatgt atgagctttg ggtaacgaat
    15541 attttgaatt aaggaaaata gtgctggaaa atatttcgtt ttttgtacag agtagtttat
    15601 ttaagaaggc tgcgtagcgt atgtccggca cagctctttt ttcatagtga aagataaggt
    15661 gataaaatga ataaccgaat ccttgaaaca ttggaatttg aaaaagtcaa acagatggtc
    15721 agacaatttg tagtgactgc acaaggaaaa gaagaactgg cagaattggt accagtgagt
    15781 gagaaacaaa cgatcacaaa ctggcttcaa gaaactgagg atggattgaa agtgcaacgt
    15841 ctgcgaggcg ggatccctat acctaaactt gaaaatatcc gtccccatat gaaacggatc
    15901 gagatcggag cagacttgaa tggagtggag cttgcacaag tttccagagt attgtctacg
    15961 acaagcgaat tgaatcgttt cattgatgat ctttctgaca gtgaaatcga atttgcacgt
    16021 ttgtatatgt gggcagatca gttagtcacg atccctgttt tgagccgccg tttaaaggaa
    16081 gcaatcgatg aagacggacg cgtgactgat gacgcttctc ctgagttaaa gagcataaga
    16141 cagaacattc ggcgaagtga acaagctgtt cgtgaacagt tagatgggat cgtccgtggg
    16201 aaaaatgcaa agtatttaag tgatgcgatc atcaccatgc gaaatgaccg ctacgttatc
    16261 ccagtcaaac aagaataccg cggtgtattt ggcggtgtag tccacgatca aagtgcttca
    16321 ggacagactt tatttattga accaaaacaa gtggtggatt tgaataatcg tttgcgtcaa
    16381 taccaaatcg ctgaacgaaa tgagattcaa cgtattttaa gtgaactttc tgctgaactt
    16441 gttccccatc gtcaagaaat catccacaat gcttatgtga ttggtaaaat ggatctgatg
    16501 aatgcaaaag cacgatttgg taaagaagta aaagccatcg tgccgggaat cagtgaagac
    16561 aatcatgtcg tcttgaaaca agcaagacat ccactgatcg atcaggaaaa agtagtttct
    16621 aatgacatca caatcggaaa agactatcaa gccatcgtca ttacaggacc taacacaggt
    16681 gggaaaacga tcacgttgaa gactttaggt ctgttacaac tgatggggca agcaggatta
    16741 ccgattcctg caggtgaaga aagtcaaatc ggtatttttg aggaagtatt tgcggatata
    16801 ggagacgaac agtcgattga gcaaagtcta tcgacctttt cttctcatat gacgaacact
    16861 gtagatattt tatcaaaagt caatgaaaaa agtctggtat tatttgacga gctcggtgca
    16921 ggaacagatc cgcaagaagg tgctgctcta gcaatcgcaa tcttagatga tcttggtaaa
    16981 aagtctgctt atgtgatggc aacaacgcat tatcctgaat tgaaagttta tggatacaat
    17041 cgggcaaata cgattaatgc cagcatggag ttcgatgtgg atacactaag tccaacgtat
    17101 cgtttgctga ttggcgttcc tggacgaagc aatgcgtttg aaatctctag ccgattaggt
    17161 cttgatacag aagttattga tgaagcgaag cagttgatga atgatgagag ccaagattta
    17221 aacgaaatga tcacagattt agagaatcgc cggaaaatgg cagagaccga atatctggaa
    17281 atgcgtcatt ttgtttctga ggcacaagaa cttcacgatg atttgaaaga agcttacagc
    17341 tatttctttg aagaacgtga aaaagaaatg gaaaaagcaa agaaaaaagc aaacgaagtc
    17401 gtgtcagagg cggaagaaaa agcagaaaaa atcattgctg atattcgtaa aatgcaacag
    17461 cagattgggc aaggaaatgt gaaagagcat cagttgatcg atgcaaagac ccaattagca
    17521 aatctacatc aagaagaaac tttgaagaaa aataaagtat tgaagaaggc gaaagaacaa
    17581 aaaacgttga aaccgggaga cgaagtgttg gttacgactt acggccaaag agggacgctt
    17641 ttacgtaaaa acgggaatca gtggcaagta gaaatcggta tattaaaaat gaatgtgtcc
    17701 gaagacgagc tgacgcctgt tgctcctcaa aaagagccga cacaacgagt tatccatgct
    17761 gtacgatctg aatctagtag tcacgtgccg aatcaattgg accttcgagg aaaacgatac
    17821 gaagaagcgc taagtgaggt agatcaatat ttggattctg ccattctagc tggttatcct
    17881 caagtgacta ttgtccacgg aaaaggaaca ggcgcacttc gcaagggaat tactgattat
    17941 cttaaaaacc atcggagcgt caaaagcttt gagtttgcac cggcaaacca aggcggaaat
    18001 ggtgcgacaa ttgttaaatt taagtaaagc ttactaaagg taagcagatg gttcgctatc
    18061 caagtataga aatgctatac taatcataga ttttaaaaat ggaggtcttt gatatgtcac
    18121 aagtaattac agataagaca tttaatgaag aaacagataa aggacttgta ttgattgatt
    18181 tttgggcaac ttggtgtggt ccatgtcgta tgcaagcacc gattttggat cagttggaac
    18241 aagaatatga tgaagaagaa ttcagaattg ctaaaatgga tgtggatgaa aatccagaaa
    18301 ctcctcaaca attcggtatc atgagcattc caacattaat gttgaaaaaa gatggtcaag
    18361 tagtagaaaa agctgttggt gttcattcaa aagaacaact acgtcaaatg atcgatcaat
    18421 atttataaaa acttacagca aaaataagct gagggtggga ctgaatccag ttccgtcctc
    18481 ggtttttttg cggttgagtt aaggttattc aaattaatat tttttgagta taattacgtt
    18541 gtcaggctgg attgtttttt tgacagacat gctataataa ctttaattga atatgaaggg
    18601 gagtaccaga tgaacgaacg aatcaaaaac aaattagctt tacttcctga tcagcccggc
    18661 tgttacttga tgaaagataa aaatggaacg attatttatg tcggcaaagc caaaatatta
    18721 aaaaatcgtg tccgctcata ttttactggc agccataata cgaaaacgga acggcttgtt
    18781 agtgaaatcg aagactttga atacatcgtt acagaatcga atatcgaagc attgctctta
    18841 gagatcaatc tgataaagaa aaatgatcct aaatacaaca ttatgttaaa ggatgataaa
    18901 acctatcctt tccttaagat aacgaatgaa aaatatcccc gtttggtgat tactcgtaaa
    18961 gtactaaaag acaaagcact gtattttgga ccatatcccg atgtcggtgc ggcgaatgag
    19021 acaaagaaga tcctcgatcg attatttcct ctgagaaaat gcaaacctag tcagacgaag
    19081 gagccttgtc tttactatca tttgggacaa tgtctgtgtc cttattattt cgacgtagat
    19141 ccgaaagtct atacgaaaat cgttgatgaa gtgaaaaagt ttttaaacgg aggacacgaa
    19201 aaaatcgagt cagagatcca tcagaaaatg gaaaaagctg ctgaaaacat ggagtttgaa
    19261 aaagctgcag aataccgaga ccagatccgt gccattgaga caatcatgac tcgccaaaaa
    19321 atgacaaata ctgatttact ggatcgagat gtatttggtt atgcgattga caaaggatgg
    19381 atgtgtgtcc aagtgttttt cgtaagacaa ggaaagctaa ttgaacgaga tgtttcaatg
    19441 tttcctttct ataacgaagc agaagaagat ttcttgactt acctcggtca gttttatcag
    19501 gaaaatgagc atttcattcc taaagaagtc ttgattcctg atacgatcga caagcccagt
    19561 gtagaagctt tgttagctac gaaagtgctg caaccaaaac gaggagaaaa gaaaaaatta
    19621 gttgaattgg cgaataagaa tgcctcagtt gctttgaatg aacggtttga tctgattgcc
    19681 agaaaacagg aacggacgat cggagcagtt gaacgtttag gaaacgcgat gaatatcccg
    19741 accccaatac gtatcgagtc ttttgataac tctaatatca tggggacgaa tcctgtggct
    19801 gcgatggtcg tattcattga tggaaaaccg gcaagaaaag aatatcggaa atataaaata
    19861 aaaacagtca acggaccgga tgattatgca tcaatgagag aagtcatcta tcgcagatat
    19921 tcacgagtga ttcgcgaagg gttgccttta cctgatttga tcttgatcga tggaggaaaa
    19981 ggacaagtag atgtggcaaa agatgtctta gaaaatcaat taggaatcga tattcctatt
    20041 gctggcatgg caaaaaacga taaacataaa acaaatgagt tgctattcgg tatagatttg
    20101 gctgtagtac cgcttgagcg aaattcacca gagtttttct tactccagcg aatccaagat
    20161 gaagtccatc gattcgcaat cactttccat cggcagctac gcagtaaaaa cagttttgct
    20221 tcccgattag atgaaattga agggttagga ccaaaacgaa aaaaaatgct gcttaaagag
    20281 ttcaaatcgt tgaaaaatat cacagcagcc acgacagaag aattacaaga aatcggactg
    20341 ccgaaaaatg tcgcacaaaa cgtatttgat aaattacatc aggaatgagg aaagggcact
    20401 ttacaaagaa agtaaagtgt cctatcattt tatgtacaac aaaaagagcg tttacgtttt
    20461 gttggtaaat aataaatcgc ttacgtctgg tgtctaagga tatatgtgat ttcttgaaga
    20521 aggagtgaag aaatgttaga agtcaaggat cttgttaaaa cttttgggaa ctacacagct
    20581 gtcgatcatg tctctttcca aatccccgat ggaaaaatca tggggctaat tggccaaaac
    20641 ggggctggga agacaacgac ttttcgtttg atcttggatt ttttgacaca agaccaagga
    20701 gaagtgttat ggaatggcca tcatcttggg gagaaagatt atgatgtcat cggttatctt
    20761 ccggaggaac ggggacttta tccgaaagta acgattcaag accaactgct ttattttgca
    20821 gaacttagag ggaaatcaag aaaagagatt gaaccaaaaa tcgatttttg gatggaaaaa
    20881 tttcaggtaa aagggaaaaa gacggataaa gtaaaatctt tgtctaaagg aaatcagcaa
    20941 aaagtccagc tgatcgccac gttaatccat gaacctaaat tgatcatttt ggatgagcca
    21001 ttcagcgggt tagatccggt aaatgctgaa ttgctaaaag atggaatatt ggaattgaaa
    21061 aaacatggtt catgtgtcat tttttctagc cacaatatgg ataatgtaga aaaaatctgc
    21121 gatcatttga tcatgttgcg aaacggaaaa atggttttga atggaaaagt acatgagatt
    21181 cgtgaatcat ttggccgtac gaagttattc ttggaatctg gtttaagcca acaggaagta
    21241 gaagaaatcg aaggcgtgaa aaaagtgatc cttcatgaag acaatacgtt agagattacc
    21301 ttagaagatc ctgaagctgg gaaagaaatc tttactcgtg cgactcagtt cggctacatt
    21361 cctatgttta accagcaacc gccaactttg gaagagattt tcaaattgaa agcaggtgaa
    21421 atcgatgcgt aagttttgga ttattaccaa agatgtctat ttaaaaaatg ttaagtcgat
    21481 ttctttcttg atcatgatat tagtcccttt tatcatgctg ggtatcattt atgtagcagg
    21541 aaactttgct caacaaaata gtgatgtcaa taaaatcggc gtattggctg ataatgagca
    21601 aatcagtcag caaatgagcc aagtcaaaac agatgatttt gagttcaaag cagttgattc
    21661 tgaagaaaaa gcacaaaaag agctttcgga agaaaaaatc gatgcgtatt tagtagtctc
    21721 aactgagaat gataagataa atgggatgct ttatagcgaa aattcattag gacaaagtac
    21781 acaactactg atacaacaac aactgactgg cttgcaatcg atgcttcgag caagtcaatt
    21841 aggcatttca ccagaagaag tagctagctt gagccaacaa gcaagtttga ctcgacaaaa
    21901 agtcaatttt gattcaaaag gaaaaatgac agttggagaa gataactcga cagtccaata
    21961 tgtcgtaagt tatgtagcaa cgattgtctt gttcattatt attttgacgt atgcgcagat
    22021 cattgcacaa gagatcgctt ctgaaaaagg cacgcggatc atggaagtga tcctgtccag
    22081 tacgactgca caaaagcatt tttacggaaa actaacaggt gttttacttg ttgcattaac
    22141 gcaaatggca ttatacggta ttatttttgg tataggatac agtcaattca aagatatgga
    22201 aatggtcaaa aatatattag acggtatctc attggataac ttgattggac cattcttgtg
    22261 gtattctctt ctattcatga tctttggcat tttgattttt tctgttttag cagctttatg
    22321 tggctctttg gtcaacaaag cagaagatac agcaaaagca attttgccag tgacttatct
    22381 atctctaggc ggatatatgc ttggattgat actaggagct tcagatccaa acaatatcgt
    22441 tattcggatc acttcgtata ttccattctt atcttcatat attatgccgg ttcgcttagc
    22501 aaatgagaca gtcggtatgg gtggagcatt gatttccttg ttggtacttg tagccgtaac
    22561 attcttattg atgatcttgt ctgcaaacat gtacaaatcg aatgtactcg tgtatagcga
    22621 aggcggatta tggagttcat tgaaacaatc gatttcaatt atgagaaatg aacgaaaaaa
    22681 agcataaaat atagaaaaat atagaaggaa gctggacatt tattgttccc agcttctttt
    22741 ttgtatagac ctatttctat ttttttatta tattggatat atattcattg aaaatagagc
    22801 ataacaactt tataatgttg agtataccaa tttttggagg cgttttaatg gaccgctatt
    22861 tagatttact ttcagagaag ttccctacaa cggaagatgt catcacggaa atcatcaatc
    22921 tcgaagcaat tttgcagctt ccaaaaggaa cagagttatt tttgagcgat atacatggcg
    22981 aatttcctgc ttttgatcat attctgcgta tcggttcagg aaatcttaaa gaaaagatca
    23041 aagacctttt ctctgaacaa atgacggaaa cggagatcag ccaattcact atttttacgg
    23101 cttatccaga atatgtgttg acgactgatt ggtacaaaaa acaagataaa tcccagctga
    23161 tccatcgttt gatcgatctt ttacggttta cgacagtcaa atacactcga tcaaaagttc
    23221 gaaaaggatt gccgaaagaa tatagctata tcattgagga actcttgtat atcgatgatc
    23281 gtatcaacgg gaaaaaagac tatgtaaaaa aaatcattga acaacttgtc ttgatgaagg
    23341 aagaagaaaa atttttaaca aaacttgcgc agacgatcca aaaatctgtc atcgatcatt
    23401 tgcatatcgt gggtgatatt tttgatcgag gaactcaagc agccaaagta atggatcgaa
    23461 tcatggattt ttcctctgta gatatccagt gggggaatca tgatattttg tggattggtg
    23521 cgtattgcgg ctctgaggca tgtttattga cgcttttacg gattgccgca cgctacaact
    23581 atttatttga attagagaaa gaatatggat taaatttacg tccattattt tcttttgccc
    23641 atcaaaccta tcagaagaat ccagtattta cccctaaaaa caggaaagat ctatctgaaa
    23701 gagagcaaga agaattagaa aagatccatc aagcactttc tatcctccaa ttcaaatcag
    23761 aacatcagtt gttgaatcga cgacctgaat ttaaaatgga cgatcgtaaa ttgttggaaa
    23821 aaatcaacta tgaggaatca acgatcgttt tagaaggtca gctctatgag ttgaaaggga
    23881 cttgttttca aacgatccag ccagatgatc ctaaaaaatt cttggaagag gaacaaaaag
    23941 tgatcgatag tttgatgtat tcattccagc actcgttaag aatgcaaaaa cacatgacgt
    24001 ttttgatcga aaaaggggga atgtatctca cgaacaatca gcatgtactg ttccatggct
    24061 gtatacctgt agatgaaaag gggcagctct tagcatttga attagaccaa tcttatcgcg
    24121 gaaaagaact gctgggattt tttgaaaaac agataactga aagcgcaaaa gatttgactg
    24181 caaatgaaga tttggcgacc gatttgattt ggtatgcgtg gagcgggcca ttttcgcctt
    24241 tattcggcaa gagtaaaatg gcaacttttg agcgctattt tctcacagag cctcatacgc
    24301 acgtcgaaaa aagcaatccc tattatcact tgcgagatga agagtggttc agtgaaaaaa
    24361 ttttggcaga attcgatgca aaagaagaag gttcagcaat catcaatgga cacacgccag
    24421 taaaagtaaa aaaaggagag tcaccgatca aagcaaacgg aaaagcattt gttattgacg
    24481 gaggtctatc caaagcttat caaaaaacaa ccgggattgc tggctactca ttactatgca
    24541 attcttacgg tttccaaatc gtgacacatt atccgttctt gcctattgaa caacaatttg
    24601 caaaaaaatc tgatcaaacg aatgtaaaaa aagtgatcga gcagcagctc ccacgcaaac
    24661 ttaatcggaa tacgacaaaa ggaatggaat tacagcaaca gattactcaa ctccaaaggc
    24721 tgttggatta tcgaaaggac gattgagaaa aatgctagcc aacattgctc aatagactaa
    24781 aaagcgactg caacaaaagg cgtgtcgcag tctccttcgg aattagctca aaaaacggta
    24841 aaatattaga agctattttt ctgtttattt ctctaatact caggtcaggg cgctgatttc
    24901 acgacctctt ccttaaacgg tgttctcctg ccaactcctc ggtcacaagt cacaatatcc
    24961 aacaaacatg agaagctgtt ttttgaaatt gctccttgtg actcagagtt gaacggcagg
    25021 ctcacgacct aatcagaaaa acgattaaaa ttcattcaca aagaaatcga ataaacgctg
    25081 ttcagatgaa tctacacgat gagaaagttc cggatgccat tggacaccaa ggattttgtg
    25141 catattatct ttactttgga ctgcttcaat gagtccatcg ttggaaaagg cgatggcttt
    25201 taacaaagga gaaagatctt tgactgcctg atgatgatag gaattcacaa agtatgaatc
    25261 agggagaagg tcacttaata aactgtccga aacgattttg acttcgtgag ttgcaaactg
    25321 cggggcagtg ggctgttgtt cgtgttttac ggaccatttt ggatataatg aaagatcttg
    25381 ataaagtgtt ccctccaaca cgacattcaa tagttgaagt cctcggcaga ctgcaaaaat
    25441 cggttttctt tgtttcaatg cttccaagat caatgcctgt tcgaattggt ctcgttgaat
    25501 atttgtttcc gtcagttttg gatgagggtc ttccatgtaa agttgcggac taacatcctg
    25561 accgcctgca agaatgagtt tgtcgatttt ctcaattagt tgaggcgctg aatctggaga
    25621 catgactggc agaataagag gtaatccttg agcatctaaa actgcatcca caaatccctg
    25681 cggtgtatag cttacttgat ttccttggaa agtatctgtc gctcgaatca gttgattccc
    25741 ggcaatgccg atgattggtt tcatttttat tccccctaaa gtagactaat tgtaacaagg
    25801 atttaaaaaa atttaaacta tgtaagactt gcccctatac ttatctgttc ttgctgtgtt
    25861 actatctgta aagagaattt tcgtgtgaaa ttcatgacga tagttgaaaa tattgcttaa
    25921 tttgttataa taaaaagtaa gcagaaataa aaaggttggg cgtaagcttc aaggatctag
    25981 ttcttcaagg ggtgagaagg acattttatt gaaggggcct gcctatacta agttatcttt
    26041 agaggtacat actttcaatg aaaaaagaaa gcatgtacct cttttttaaa tcgaaaggaa
    26101 gtgaagcaag tgttagaagc tttggaacaa atccgaaaag cagaagaaga aaatgagaag
    26161 cgtgctcgaa ccctacggca gcagttgaag acctatgcag aagaaaaaga gcaagaattg
    26221 gagataatcc aaacgaacag tcggcaacag ctgaaacagt tggtagaaga aaaagaacaa
    26281 ttcgaaaagc aagaattaga aaaagaaaaa atgaaattga aagcagaagc agacaaggtg
    26341 caagcaactt tgaaagacca atatcaaaag catcagagtc aagcaatcgg tgcaatcatt
    26401 gaaagggtga aagaaactta tggccgtcac taagatggaa aaagtgaccc tcatttcaga
    26461 taaaagaaat caggagagga ttttacaagc agtacaagga atccaaaatg ttgaaatccg
    26521 ggatctgtat caaaatagaa caaacaacca gtgggtagaa aaatattttc cagataccac
    26581 gattattgat aaagaagcaa aattaagcgc tttaggcaat cggctgaaag acatccaaga
    26641 agctatccaa ttcatacaac accacggcga tagccgtcaa aagaaactcc atttgaaacg
    26701 tcaagaactt tccttacaag acttggaagc aaattattcc gaagaaaatt tcatgaataa
    26761 attagaagag gtccttgatt taaaagaaaa gtgggaacag ctaactgaaa aacgtgatcg
    26821 tttagaagaa gaggaagaat ggcttcttca ttggcaacag ctggatattg ctccaagtat
    26881 gtatgcaagt aagacgacca tttttgagat ggggactgtg agtgcagcaa attttgaaag
    26941 tttcaaggaa gaactaagta agcttgatga cgtttatatg gaagaaatag attatacgcc
    27001 aaaacaagtt tatctttcgt atgttgcttt aaaaaaatca gttgctgcta tagaagaaat
    27061 tgctgggaaa tacgggttca ataaagaaac gtatccttat gaacaaaatc ctaaagaaaa
    27121 attgcaagaa accaaacagc aattatccat tgttcacgag cagcaaaaaa agataacgac
    27181 agcgttaggt cagtgcagcg gctatatcca agaatttgaa tgggtagaag aagtcacact
    27241 tgccgttgca gaacgggaaa aagtaaaaga acggtttatc catgccactt atctgatcgt
    27301 tttgcaaggt tgggtagatg cagaagaaaa acagaatttg atgcatgtgt taaacgaaac
    27361 tgtatcagaa gaagatatat acgttagttt cgaaacacca aactcagaag agattcagca
    27421 ggaagtccct actaaattga aaaaccatcc gcttatcgaa ccttttgaat tgctgactga
    27481 aatgtacagt ctgccaaaat atgaagaagt agatccaacg ccttggatga caccatttta
    27541 tcttgtcttc ttcgggatga tggtcgcaga tgttggttac ggattgctga tgctcattgg
    27601 gacaatacta gctcaaaaac tatttgtttt accccgcggg atgaaacgtt tcgtaaaatt
    27661 ctttgagatt ctctcggtac catcgatcat ctggggattg atctacagtt catttttcgg
    27721 acaggcatta ccaaaagaac tatttggtat ccgcttgcct ttcccaatcc tatctacgac
    27781 ggatgacgtc aatacgattt tgattttatc cgtgattttc ggtctgatac agatcttggt
    27841 tggattattc gtggcagcaa aggaaaatat caggaggaaa gattacttga gtgctgtcag
    27901 tgatggtttt gcctggcaag ggatcctgat tgggatcgtt attgcattga ttggtgtcat
    27961 gttgataaaa aatacagcat ttgtttatct tggcgcgggg ctatcgatca ttgctgcttt
    28021 atgtatctta atcgtgccga ttatccaatc gccgtctaaa gtcaagggtg ctgccaaagg
    28081 agcgtataat ctttacggat tgactggtta tatcggtgat ttagtcagtt atacacgttt
    28141 gatggcacta ggtatttcag gcggaagtat tggcgcggca ttcaatatgc tagttgcttt
    28201 catgccgcca gccgctcgat tcagtgtagg gatccttttg atcatcgctt tacacgcact
    28261 gaatatgttt ttgacactgt taagtgccta tgtccatggt gcacgattgc agtatgtcga
    28321 attttttgga aaattttata caggaggcgg acgtgccttt gacccgctga aaacggcgga
    28381 aaaatacgtc aacatcaatc ataagaaaaa aaacaataaa taattggagg atttttatac
    28441 aatgatggat tacttaatta gtcaaaatgg tggaatggta tttgcagtat tagcgatggc
    28501 aacagcgacg attttttcag ggattggttc agctaaaggt gttggaatga caggtgaggc
    28561 agcagcagcg ttaacaacaa gtcaacccga aaaattcgga caggctttga ttctgcaatt
    28621 gcttccaggt acgcaagggt tgtatggatt cgttatcgcc tttttgattt ttatcaactt
    28681 aggaaatgat atgtcagttg tacaaggatt gaactttcta ggcgcttctc tgccgattgc
    28741 ttttacaggt ttgttttcag gtatcgccca agggaaagtt gcagcagcag gtatccaaat
    28801 tttagcgaaa aaacctgaac atgctacaaa aggaatcatt tttgctgcga tggttgaaac
    28861 atatgcgatt ttaggtttcg ttatttcctt cctattagta ttgaatgcct aagcataaag
    28921 gaggaaaagc agatgaacgc cattgaaaaa atcatctctc agatgaatga agcagcagag
    28981 caagaaagag cggcgttaga gcaagaagag cgaatgaaga tcgatcaaaa ctttgaacaa
    29041 aaacgtacgc aaatcgaaac agaacatcaa aaacaaaaag aaaaacaaat cgaattactt
    29101 gaaaaaaaat accgtcagct taggaatcgc caacaagtag aagtacgaca agaaaatttg
    29161 aatgcgaagc aggaattttt acgacgattg tttgcagatg caatagctga aatggagaat
    29221 tgggatgaat ctgaacaaat ccagtttatc aaaaattcat tgtattcatt acctttgaca
    29281 ggcaaagtaa cattcattgc tggagaaaaa tcagcagctt atctttctca gacattgctg
    29341 gatgaatgga acaatgaact tccctttatg atggttttaa gtgatgaaac tgttgctgat
    29401 caagcgggtt ttctgataaa cgatcaagga gttcagtata attttctttt cagcagcctt
    29461 gtacaagata tccaaggaac gatgagtttt gagattgcca atcaattatt cgaataagga
    29521 gggatcagtg tatggaatac cacgaactaa atcccttgat tcgcggaaga gagcttgaac
    29581 ttttgtccaa tgagacattt gaacggatga ttcaaacaaa ttctgtcgaa gcacttggtg
    29641 aaatattgaa atccacgatt tacagtccat atatttatga cggatatgaa tatgacttcg
    29701 aacagaatct tttaaaggag cagagccgtc tatttcgctg gttaaaggaa tcagcaccgg
    29761 agcctgaaat cgtttggatc tatacgatgc gctatacttt ccataatctg aaggttttga
    29821 caaaagccga gatgacaaat caaaatctgg accatttgta tatcgacgat ggattttatt
    29881 cattagaaac cttgaaggat gccattcata cgcaagtttc aaatgaactc cctgaaagca
    29941 ttatggacag tatacgagaa gtacgtgatt attttgaaga gtctaccatt cttcagggaa
    30001 ttgacgtgat ttatgatcga cagtttttga cagagcagcg acggcttgcc gataagctag
    30061 gatatcaaga attgctgaca gaagtcattg cttttattga cttgaccaat atcacaacga
    30121 tggctcgagg aatattgcag aaaagaacat atgggttcat gacgacggta ctttccagct
    30181 cgggaagtat cgaaaaagaa gtatttttga actttgtaga taaagatatg gaagattaca
    30241 cgaattttct attagagaca gattatgctg attttctgcg ccctgtcatc cgtgagggaa
    30301 atcttgatct cgtaaagctt gaacagttga aagatgatta tctaagttca ttgtatcaag
    30361 aagcacaaac ccaggctttc ggaccactgc cactactagc ctttttgaac gcaaaagagg
    30421 tagaaagcaa aaaccttcgt ttactggtta tcggcaaaag aagccatttc gaaccagaaa
    30481 caatcagaaa gcgggtgaga caagtctatg acgcataaga tcggtgtagt tggcgacaaa
    30541 gattctgttt tgccattcaa attgtttggc tttgatgttc gttatggtac aaccaagcaa
    30601 accgttcgtc aggcaattga agaaatggca aagaatgagt atggcgtgat ttatgtcaca
    30661 gagcaatgtg cagcattgag cccagaaacg atcgaacgtt acaaggaaca aatgatacct
    30721 gctatcgtat tgattcccaa tcatcaagga tcattaggga tagggctgga agaaattcaa
    30781 aaaaacgtag aaaaagcagt aggtcaaaat atcttatagt atgaaaagga gatagaaatt
    30841 ttgcaaattg gaaaaatcat aaaagtctcc ggacctcttg taatggctga gaacatgtct
    30901 gatgccagta tccaagacat gtgtctagtg ggagatctag gagttatcgg agaaattatc
    30961 gagatgcgtg gcgatgtggc gtctattcaa gtatatgaag agacttctgg aattggtcca
    31021 ggcgaaccgg ttcgctctac tggtgaagct ttatctgttg aattaggacc agggatcatt
    31081 tcacaaatgt ttgacggaat ccaacggcca ttagatacct ttatggaaat cacacaaagt
    31141 aatttcttag ggcgcggagt tcaattgccc gcattggacc atgagaaaaa atggtggttc
    31201 gaaccaacag tagaagccgg agaaacggtg agtgctggag atgttatcgg gatcgtagaa
    31261 gaaacaaaag ttataaaaca taaaatcatg gtgccaaatg ggataaaagg tacgatcaaa
    31321 acaatcgaaa aaggttcatt cactattgat gaaacagtat gtgtcattga aaccgaaaat
    31381 ggtgacaaaa atttgacgat gcttcaaaaa tggccagtaa gacgtagtcg gccaatcaaa
    31441 gaaaaattaa acccggatgc acccatgatc actggacagc gagtgattga tacattcttc
    31501 ccagtgacaa aaggaggagc agcagctgta cctggtcctt ttggtgcagg gaaaacagtc
    31561 gttcagcatc aaattgcaaa atgggccgat gtggacatgg ttgtctatgt gggatgtggc
    31621 gagcgtggaa atgagatgac ggatgtttta aatgaattcc ctgaattgat tgaccctaat
    31681 acaggagaat cgttgatgga acgtacggta ttgattgcta atacatcaaa catgccagta
    31741 gcagctcgag aagcttctat ctatacggga atcacaattg cggaatattt ccgtgacatg
    31801 ggttatgacg ttgctatcat ggcagactcc acttcacgat gggcagaagc acttcgtgag
    31861 atgagcggac gtttggaaga aatgcctggt gatgaaggtt atccagctta tcttggttca
    31921 cggcttgcgg aatactatga acgatctgga agagtcattg cattaggatc agaaggtcgc
    31981 gaaggaagta taaccgcaat cagtgctgta tcgccgtctg gaggggatat ttcggaacca
    32041 gtcacacaaa atacattgcg ggtcgtaaaa gtattctggg gtcttgattc cagtttagcc
    32101 caaaaaagac attttccttc gatcgattgg atacaaagct attctcttta ttcaacagaa
    32161 gtagggaagt atatggatca tatccttcaa gctgactggg catccatggt caccgagggc
    32221 atgcgtattt tgcaggaaga acagcagctg aatgaaatcg tgcgtttggt agggattgat
    32281 tccctttcag ataatgaccg tctgacatta gaagtggcaa aatccattcg tgaagattat
    32341 ttgcagcaaa atgcttttga tgatgtcgat acattcactt caagagagaa acaattcaaa
    32401 atgttgaaga tgatcttgac ctttggtgaa gaaggacgcc gtgcgttgtc gttaggtgct
    32461 tatttaagtg agatcatgga cggtaccgta tcgattcgtg aaaggatcgg acgaagcaaa
    32521 tatatcccgg aaacagaatt agaaaaacta gatcaaatta ttggtgaaat caagcaaacg
    32581 atgcaaacga tcgtttcaga aggaggcatg agcaatgatt aaagaatatc gtacgatcgg
    32641 tgaagtcgtc ggtccattga tggcggttga aaaagttgct ggtgtcaaat atgaagaatt
    32701 aatcgaagtc cgtatgcaaa atggcgagat tcgtcgtgga caagtattgg aagtccaaga
    32761 agataaagca atggtccaaa tattcgaagg aacaagtggt atcaatttac gtgactcttc
    32821 tgtacgattt ttaggccatc ctttagaact aggtgtatcg gaagacatga tcggtcgagt
    32881 attcgatggt ttgggacgac cgaaagataa cggaccagag atcctgcctg aaaagcattt
    32941 ggatattaac ggagaagtaa tcaatccagt agctcgggat tatccagatg agtttatcca
    33001 aacaggtatc tctgcaatcg atcatttgaa tacattagtt cgtgggcaaa aattaccagt
    33061 attttctggc tctggtcttc ctcataaaga attagctgct cagatcgcgc gacaagcaac
    33121 ggtactcgat tcatcagatg atttcgccgt agtctttgct gctattggaa tcacttttga
    33181 agaagcagaa tttttcatgg aagattttcg tcaaacgggc gcaatcgacc gttctgtcat
    33241 gtttatgaat ttagcaaacg accctgcaat cgagcgtatc gctactcctc gtatggcttt
    33301 gactgctgca gaatatcttg cttatgaaaa gggaatgcat gttttggtta tcatgacaga
    33361 catgaccaac tatgcagagg cattgcgaga gatttctgca gcacggcgag aagttccagg
    33421 aagaagagga tatcctgggt atctttacac gaacttagct actttattcg aacgagcagg
    33481 aagaatccgc ggactaaaag gatcggttac tcaaattccg attctaacaa tgccagaaga
    33541 cgataaaact catccaatcc ctgacttgac tggttatatt acagaaggac agatcatctt
    33601 gactagagag ctttacaaga gtgggattca gccaccaatt gatgtactcc cgtctctttc
    33661 gcggttaaaa gataagggaa ctggacccgg aaagacaaga gaagaccatg cagctacgat
    33721 gaatcagctt tttgcagcct atgcacaagg aaaacaggca aaagaattgg ccgtagtttt
    33781 aggtgaatct gctttatctg atgtagacaa gatctatgcg aagtttgctg agcggtttga
    33841 aaaagaatat gtcaatcaag gattctacac gaaccgttcg attactgaaa cacttgatct
    33901 agggtgggaa ctgctatcga tgttgccaag aaccgaatta aaacgaatca aagacgacat
    33961 gctggacaaa tatctgccag aagggaagtg agttctgatg gcacgattga atgtgaatcc
    34021 gacccgcatg gaattgactc gattgaaaaa acagttgaca actgccacaa gagggcataa
    34081 attattaaaa gataagcaag atgaactgat gcgtcaattc atcctgttga ttcgaaagaa
    34141 caaccagctg cgtcaagaaa tggaagagtc tatgacagaa gcaatgtctg attttgtatt
    34201 ggcaaatgct tcgatcacgg agcctttcat cgaagaatta tttgttttgc cggcggaaaa
    34261 cgttgatttg tctatcgtag acaaaaatat catgagtgta aaagtacctg tgatgaattt
    34321 tgaatatgat gaacagctga cagacacacc tttggaatac gggtatttga attccagtgc
    34381 cgaactggat cggtcaatcg atcggtttac taccctgctt ccaaaacttt tggaactgac
    34441 agaaatcgaa aaaacttgtc aactgatggc gagtgaaatc gaaaagacac gtcggcgagt
    34501 caatgcatta gaatatatga cgatccctca attagaagaa acgatctatt atattcgtat
    34561 gaagctggaa gaaaacgagc gcgcagaagt aacaaggttg atcaaagtaa aaaatatggg
    34621 taccactgac taagtggtat ccttttttaa aagaggaaaa cgatgattaa acaaagcaaa
    34681 caaataaaga aacgcttgcc ggctgttcag cttctcgcat taggattttt tctcctgatt
    34741 ttagttggcg gcggcctact taccctacca ttttttagta atagtgggca tgggacaaat
    34801 tttatcgatg cgcttttcac tgcaacttct gctgtctgtg tgacgggatt gacaacattg
    34861 aatacagcag agcattggaa cagtgctggt caatttttga tcatgctttt gattgagatc
    34921 ggcggtcttg gttttatgat ggttccgatt ctatgctttg cattgataaa gaagaaagtc
    34981 agtctcagca cacgtattat attaaaagaa gcgctgaatc tagaagaagt atcaggtgtg
    35041 atgaagctca tgctttacat cctgaaattt gcctttgtga tccaactgat tggtacggtt
    35101 gctttatctt ttgtattcgt gcctgaattt ggctggttga aaggtatctg gtacagtttg
    35161 ttccatgcaa tctctagttt ttgtaatgca gggtttgatt tgttaggaga cagtttagcc
    35221 aatcaccagc aaaatgttta tttgatcatg gtggtatctg ctttgatcat ttctggtggg
    35281 ttaggcttca tcgtatggcg tgatttactg gaatatcatc agaaaaagaa gataacgatt
    35341 cattcaaaaa tcgcattaac cgttacaggt acccttttat taggcggatt cgttgtgttc
    35401 tttttcacag agcgcaatgg ggaaacgcta gtggaaggga atatgtttca acgattggca
    35461 aacacctttt ttatgagtgt gacacctaga acggctggat attattcagt tgattacctc
    35521 catatgagcc atgcaggtct gattttaacg atgtttttga tgtacatcgg tggaacatct
    35581 gggtcgacgg ccggcggatt gaaaacaact acgttaggtg tgttgctgat ccagatgcgt
    35641 tcgatgctta aaggacgtac gagagcggaa gcatttggcc gtaccatccg acaaggcgca
    35701 gtgttgcggg cacttacttt attttttgtt acgttgacgt tgtgtgtagt cgccatcatg
    35761 attttatcgg tgactgaaac gatacctaaa acttctggca tcgaatatat tgcttttgag
    35821 gtcttctctg cgtttggtac agtaggtctt acgatgggat tgacgccaga cttgactgca
    35881 atagggaaat tgatcattat agcgcttatg tacattggac gagttggtgt attgactgtg
    35941 gtcttctctc tgatgacaaa agcacaaaga acacaatcaa aatacaaata tccagaagaa
    36001 agtgtcatga ttggataatt tcatcttctg acagaaacct agtgatttag taaaataaga
    36061 aaataaaata atttttcttg cttcttggat actttaagtg caaaatgttc gtttattttt
    36121 tgaggcacta tccgttgttg aacctcgggt agtgcctctt tcttattgaa aggaatcaat
    36181 aagatttgat tcctttattt atcaataggt tataattcat atttttttat tttttctttt
    36241 acgatactta gtccagaagc taaaatttca aggttattag aggataggga aattcgaacg
    36301 aatgcatctg gttgcgcacg tgtagtaaag cgtctggaat gataaagtcg gataccgtta
    36361 gcaagaaagt cattctcaat tatcttagga tcaatctcag gatcaactgg aagaattcga
    36421 tagtaaggga cacgattcgt tggtttttct actttgaaaa gagaatcaaa aagctgattg
    36481 gctcttttcg taagacttaa tttagtttct aagatcctat ttgcttcatt tgaatggagg
    36541 atttgagtga tgacttccac atctaatcca gaagttttca catttatatt aaaaattgct
    36601 tgttctatct tgttttggac atgtactgga actacaagat aagcaactcg caatccagaa
    36661 caaataaatt ttgtcattcc agctaagtag attgtttggt taggtaataa tttttggaaa
    36721 ggaggaatga tcgtatgttg atagtaagtt gttaaaaatg aatggatatc atcttcaata
    36781 acccatagac cttctttttc aatcacttcg gctaattgct ctcgtctttt gtgagagatt
    36841 tgaaacccta taggattatt acaagaaggc ataagaaaga caccatgaat cttctttttt
    36901 ctacattcct gaatcaatat atcaggtcgc attccttgct cgtcaaaatc aattggaacg
    36961 atctctaaat gatataactg agccaattca atgaaattag cgtatgtata tcggtctgtt
    37021 gctattctat cacctggaga gaaaagtgca gaaagtgtga tagccaatcc attttgaaca
    37081 ccggaaacaa tagatagaga ttctaaggac ggaatgactc cttgagtttt taaccaattt
    37141 gctgcagtag tcaattgaaa atttgtgcct ttgggatctt ggtaattaag caaaccaaca
    37201 agatttgggt tattactagt tgattgaata aacgggacaa cgaatttatt acattcttca
    37261 aaagaactaa ccagaccaaa atcaatgata tgttcggtta cttcattggt agagatggtg
    37321 atggactcaa agacattggg agaaataaat gtgccacttc caatattcgt atacagcaaa
    37381 cctttctcaa ttccatattt ataagccttg ccaacggtag taaaatttaa atctaaataa
    37441 tcagctagct ctctttggga gggtaactga gtgtttttct gtaatttatt ctttaaaata
    37501 tcttgttcta attgttgaat caacgatcga taataaggac gcttcaattt ttgtttgtct
    37561 ggtcgccaag ttaacgggta attgtcataa gaattaatag gcattttcta cactccttaa
    37621 aattgtatac catacaattt taccattgat tgtattgatt ttagaagtta atcttttgtg
    37681 aggagggaat tgtctatgaa aattattaat tttgaggaag tagtagcttc ttttagtttt
    37741 gaagaagcga ttcaagtaat gaaaaaatgt ttttttgatt atgaaagtgg taaaatcagc
    37801 caaaatcctc gattggtgga aattttacct gacggaaaag acaaaaatat gtttgcgatg
    37861 atgcctgctt atttggggga gaacagatat tttggaacaa aagtcattac cgcttttccg
    37921 gataatcatc agtatcattt accttctcat ttaggagaga ttttcttgtt tgatgctcaa
    37981 aacggactac ccaaagcatt gataaacgca aatgcagtca cctggattcg aacagctgct
    38041 gtatctgcgc tggcaacaga ttacttagca aatccgcatg cagaaacact tgctttaatt
    38101 ggagctggtc aacaagcatt gtcgcatttg actgcgattt ctaccattcg tcccatcact
    38161 acagtgtttg tttacgatat tttagaagaa agacgaaata cttttatcgc taaagctaaa
    38221 aaacagtatc ctaaaataac gtttataaat gcaatatcag tagaagatgc agtacgtcca
    38281 gcggaaatca tttgtacgtt gacctctagt aaagaggcat ttcttcaaaa agagtgggta
    38341 agggaagacg cacatatcaa tgctgtgggc acatttactc ctgatacaag agagataagt
    38401 acatcgttga tggaaacttc tcaaatctat gtcgatgatt actcagctac cttaacagaa
    38461 agcggggacc tgcttatagc catggcagaa ggagatttag aggaatcttg tattgttggt
    38521 acattaggcg aattagtttc tgagaaaaaa acattttata aaggagaatc gaggccgacg
    38581 attttcgacg cagttggtct agctattgaa gatctttgtt gtgcagaata tatttataac
    38641 aaattagaga aaggggcttt aaaatgaact tagattatta cgtagttgat gcatttgcag
    38701 atgaggtgtt caaaggaaat ccagcagcgg tttatgtgct agaagaatgg ctgccagaag
    38761 gtacgatgca aaaaattgcc attgaaaaca atttatctga aacagcattt acagtgaaga
    38821 aaaaccaaga atttgagctt agatggttta cgccagatcg agaaatcgat ctttgtggtc
    38881 acgcgacatt agcaacagca tttgttttat ttaactatta caaaatacct gatgaaacga
    38941 ttaaattttc tactcaaagc ggtaatctat ttgtgacaag aattaaagat tattattaca
    39001 tggattttcc tagtattatg ccgaaaaaag tgccgatatt gactgaatat gaagaagcaa
    39061 ttggggctaa gattaaagaa gcctacttag cacgtgattt atttttcgta ttagaagatg
    39121 aaaaaacggt ggctaaattg cagccagatt ttacagctat caaaaatttt gaattaggaa
    39181 tagagtcatc gtgacagcag aaagtgtgca aaaagacttt gtttctagaa ccttctttcc
    39241 aaaattaaca atcaatgaag atccagtatg tggatcagca cattctaatc ttattcctta
    39301 ttgggcagaa agaatgaata aaacaaaatt gtcagcttat caaatgtcat caaggggcgg
    39361 ggatctagaa tgtgaattaa aagaagatcg tgtgataata ggaggaaaag cagttttgtt
    39421 ttctaaaggt acctcgttta tttgatttct ttcaaatgaa ttaaaaataa attggtggag
    39481 agtggcagcc ttatagctac aatggttgtt aaaaaaagac gcaaactttt tcaatttaat
    39541 gaaaagtttg cgtctttttt taattattgg tgtttgtttt ttattcaatc aagagtaaaa
    39601 tgccccatac taactatcct cggatgactt cgattttata accatcaggg tcaatgacaa
    39661 agtagtaaga aggcgtagtg ccaggtaatc cttttaagtc agtaatctca agacctgcag
    39721 ctttatgttg ctcgtgtaat ttttctaaat catcagctgc aatagcgata tgaccatagc
    39781 cgtctcctag atcatacgca ccatgatcat agttgtaagt caactctaat tcatagtcat
    39841 ctccaggaag tgtcaaataa acaagtgtaa atttgttttc tggaaaatca cggcggcggc
    39901 tttcttcaaa accaaatgcc ttttgataaa attcgattga tgcttcaaga tctttcaccc
    39961 gaacacatgt gtgagccatt ttcataaatt catctctcct tttcctttta ctcaatcata
    40021 acaaaaagaa gtaagaaaat agttgatttg tgcttgttca tgagaaattt ctcatgtaaa
    40081 atggatagaa aataatactg ttaaggtgga aacaattcat ggataaacca atttttggtg
    40141 aaaaaaagca atctgctaat tatcaaaccc gttatgcagc atatattgtc atagaaagag
    40201 acaagcggat tgcggtgatc gaggctccaa atggtgcttt tttccttcct ggtggggaaa
    40261 tcgaaggaga agagacgaaa gaagaagcga ttgtccgtga gctgatagaa gaaatgggaa
    40321 ttgtggcaga aatttcttct tatctgggag aagctgatga gtatttttac tcgaattatc
    40381 gtgcaactta ttattataat ccaggatatt tctttgttgc tgattcttgg aagcgtatag
    40441 gagaaccaac tgaaaagacc aataaaattt ggtgggtgag ccctcaagaa gcgcttgtga
    40501 aattgaaacg tggtagccac cgatgggcag tcgagagatg gatcgaaaaa aataaaaact
    40561 gaaagaaagc gagtagatca gctttctctc agttttttta tttattacag tacatatttt
    40621 ttgattgctt cagctacacc gtgctcgtcg tttgatgaag tgatgacatt tgctgcttct
    40681 ttgacaagag aaacggcatt tcccattgct actcctagac cagcatattc aatcatggat
    40741 aagtcgttct cgttatctcc gatagccatg atttcatctt gatcaatacc aaggtgctgt
    40801 gcgagattcg caactgccgc acctttactt gcttctttat ttagtacttc gaagtaatag
    40861 ggcgcacttt tgaccgttgt gtatttatca cggaaagttt gcggtaaacg cgcaattgct
    40921 gcatctaaaa tttctggttc gtcgatcatc atcattttga cgatgttcat gtctggtgtc
    40981 atttcttcag gtgttcgata ttttagcggc atcttgacta aacttgcttc gtggatcgta
    41041 taagcgctga tatctcgatt aggcgtgtag atcgctttgt catcgatcga atggagatga
    41101 ctgccgacac ggcgtgccat cacttcgatc tctaggaaat cttcatgagt cagtccgtga
    41161 cgggcgatga ttttacctga tttcgtttgt tgtacgagtg ccccgttata agtaataacg
    41221 taatcattat cttgaaaaag gttcaactcg tttaactgtt cctggacacc tggtaaggga
    41281 cggccagtgc ataaaacgat cgaaacacct tttgcaacag cagcggcaat cgcttctttt
    41341 acttcttttg ttacttctct tttctcattt aataaagtac catcgatgtc gatagcgact
    41401 agtttgatag acataatttc ctccaatata ttttaattta tttcaatcaa tgcgccatta
    41461 cggatatggc tggcaaattc ttgataagtt tcgtcaaata aatcataatg atcacgcaag
    41521 gagggatcaa ccatttcttt tggaaagaaa aatcgctcat ctccttgttc ttgtcccgct
    41581 aatgcagcaa caagctgact aacctgtgat aattctatca aagttccgtc atttcgcaaa
    41641 atctcgattt gtgtgcgatg tctgccttgt tctgggcgat aaaaatcata aggcagatcg
    41701 tagctagaat tcacagcagt gtaataaaca gggttatagc caaccttttc tactaacaaa
    41761 gtgagttctt ggactaattt tgaatcccgg ttgccagaaa aagtagcaga tttcagtggt
    41821 ttacgattca aaaaacgttt agctaaatca tttaaaatag gatcagcaga ttcagaccat
    41881 tgagtaaagt aagtgcccaa gaccccatca tcaagtttga ggtattcttc taaagtaaag
    41941 cttccgtcaa gaaatggcag aagtaattga gaatggagtt caaaactgct ggcatcttct
    42001 tgatacaact cgtgtgcgcg atgaagcaga tgctccaaaa tcacttccat accacgggaa
    42061 acaggatgga agtacacttg cacatacatt tgatatcggc taacgatata atcttccact
    42121 gcatgcatgc cactcatgga aaaagcgatc ccgccttcat aaggacgaat cacacgtaat
    42181 attcgggtaa gatcaaatgt tccatattct gttccagtga aataagcatc ccgaagcaaa
    42241 tagtccattc gatctgcatc gatctgacta gaaatcattt ggacaacttg tgggttgggg
    42301 taagtttttt ggatcacact agctaccttt tcaggaaaac cttcttctac tcggttaaga
    42361 atctgataca cttctgtttc tggagaagtg atgatctcta cagtgatggc ttcatgattc
    42421 gtatggaaga tatgttcaaa tgtatgagag taaggaccat gaccgacatc atgcaacagt
    42481 gccgcacata aagtcaccag ccgttcctga tcatcccagc ctccgttgcc tattttttct
    42541 tttgaaaaat ttcgagaaaa gatatcgcag attcgtcttg aaatctcata aacgcctaat
    42601 gaatgggtaa aacggctatg ttctgctccg tgaaaagtga aagaagaagt gcctaattgt
    42661 ttaatgcgtc gtaaacgttg gacttctttc gaattgatca aatctaagat tactttatgc
    42721 tggacatgga tatagttatg gactggatca cgaaaaactt tttccatagg cagcatttga
    42781 tatttataag gggttgtcat aatgtagctc ctttatgtta ttacgttgtt ccattctctg
    42841 gatttggttg ttccattgct ccagctggat ttcttttttt agccagtcgg tagaatcctg
    42901 taaatcactt gcagaataca gcttttcaaa agcttttgca aatgcttctt tgacttcttt
    42961 tacaaaaagg ggttggtcaa gcagttcttc aagtgttgcc attgtagcag gatccactgc
    43021 aggatagcca tttgtaccaa agtcttcttt taaagcagat tgataaaatc gcttcatgac
    43081 ttgcccgcgt ttttcctgat taccgttgac acttaagtac atcataacag aaatcccatt
    43141 tttgatccga cgctgagcga taccggcaaa ttttttgcca tggatgctta aatcataagt
    43201 tccaggacaa taagaatggg tgatttcgaa tgcttgtatc ggtgcctttg gaaaagcgta
    43261 tttagtcaat aggagcattt gctcgtaagc gtcatctatg gttatttttt ttgtgtcact
    43321 ttgagggaaa atcaaagaaa tatttaaaat tccttcatct gatacgatcc ctaatccacc
    43381 tgaatttctg atcactggag cgtaacctgc atctttcagt gtttggatcc cgtcacttag
    43441 aaaaggagtt cgaacatcct tcatacctaa gatgactgtg cagtcatatt gccagaaatg
    43501 taaaaagatt tgctggtgtt ctttagaata ttccgttaat atatctgtta atgcaaaagg
    43561 ggaaaagtcg tttttttgat aaatgtgctg atctagtcga atcgcagggt tcattcaacc
    43621 ggctcctttg tataaattca tattttctac aatattatac tctaaaatca aagagttgtt
    43681 ttggaaaaaa ggttttctgt aaaaatggac aagttggttg acaaaacaaa agaaactagg
    43741 aacaatgtag ctatgagaag taaaggagaa tgaataatgg aattatcaca aggaacaccg
    43801 atttcaatca aattgcgtac aaaagtaaaa cagcaagggg aagtgcaaga tttttatttt
    43861 gatttgaaag ggcaaatggt gacaattggc gatacgctgt acatacgtta taaagagatt
    43921 caggaggaga cgggcgatga gattcctgta acgatcaaat tagttccaga tggtcatgta
    43981 cagctgatcc gtgcaggaga aatgcggatg cgtttgaaat ttggctataa agaacggtta
    44041 gaaacatcct atcgaacacc atacggtatg atccagattg ctacttttac gaaagaactg
    44101 catgttagtt tgaaagaccg tcccacagca gggaaggttc gaatcgatta tgatctgttc
    44161 atgggaccgg aaaaaatcgg cgaatattat ttgaccttgg attttacagc gtaaatataa
    44221 aagaaaagtt tgattttttg tgtctgattt tgtatgataa ggagtagact gtgaaaggac
    44281 gtgtcctgat tggaaattag tgtatttgaa ggtgcaaaca aaagcgaatt atcaatgatc
    44341 gaagtagcac acgcgatctt agaacaacgt ggcgatgtca tggatttttc tgatttagct
    44401 aaccagatcc aaaactatct tgagaaatca gacagtgaaa ttcgtgattc actcgcacaa
    44461 ttttatactg acttgaatat tgacggcagc tttatctcat taggggataa tcgttggggc
    44521 ttgcgttcat ggtatgctat cgattcgatc gatgaagaag taaaccatgg aatggacgaa
    44581 gaggatgaag atactccacg tcgccgtaaa cgcaagaaag tcaacgcctt tatcaatgat
    44641 gatgaagacg cgatcgatta caatgacgat gacccagaag atacagatct gacagaagaa
    44701 gatgacgatg atctgtttga tgacgatgat gatgaagatg aagaaatcgc tgcttataat
    44761 tctgacttgc aagaaatcgg agcagatgac ccgacagatg atgaagaaga cttgccagga
    44821 aatatcgaag aagatttaag tatcatagac gaagacgatg atgatgaaga ttatgaagag
    44881 gaagaatttt ctgactctga aaaagaataa acattatttt cttacgagag gttgtgacag
    44941 agacgatcag cctatcagaa taaggaggtg tgacacgatt tttgtcacat cttctttttt
    45001 gtatataaaa atcccaagta aatacataaa aaataaaaaa attgaaactt ttagcgcacc
    45061 ttgtacgtca tattaagtga ggcagaaagg agtggagaat gatttttact ggatataaga
    45121 aaaaacggca gatcgaaaaa taccgtcacc tgctgaatgg actcatcgaa actgattatc
    45181 aaaaaatgtt ccgtatcacg atgaattacg tacatgataa agaagaggcc ttagatgtga
    45241 tgcaagatag ttttcataaa gccttgaact attttgaaaa agaaaaagag atcgagcatt
    45301 ttagtgcatg gttttatcgg atattgatcc gcacggcatt agatagttgg cgcagacaaa
    45361 aaaggacgcc tgtggactta tttgaaattc aagatatccc ccaacagtta cctttagaaa
    45421 cttccgttgc agagctccat atgattttag ataaaataga cagtccggaa aaagagattc
    45481 tgatcctcta cttttttgaa ggatttcgtt tgaaagaaat tgcaactatc ttggatatga
    45541 atgaaaacac agttaaaacg aaaatgtacc gctcattgaa tgctttacgt caaatcctag
    45601 aatgaaggag agaagagtgc catgtattcc caaaaagaaa atttaaaaaa actaaagaaa
    45661 acttataaag aacaagcaat tcccaaaggg cttaaagagg agatccgcca gcgttttatt
    45721 atcgaagagc aatcatttat aaaagcaagg cggagaaaga gacgtctcca agggttcgga
    45781 gtatctttgg ctatcgtaat gattacaaca agtagccttc tttttaatag tcaagttcga
    45841 agctttgcag aagatttacc catcttagga tcagtcattg aattgatctt aggcgaacgc
    45901 tttactgatc gatctgaaaa aatcgatatt caggtaccga agatcaatac acaaaatgag
    45961 aaagaaaata aaacaattca tggattaaat caaaaatact ttcgcgaagg acaagcagat
    46021 tttgaaaaag ctgaaaaaga atatggaaat tttgaaacgg atcattacca agttttggga
    46081 gattatcaga aaatcgtaga cgataaccgg tttctcgtga ttgaaaggca gatcacccaa
    46141 acagcagcag atagccatgt tgaaaaaaga tacgacacaa tcgacaagaa aaacagtgtc
    46201 cagctctcac ttccactttt attcaaagat gacacttatc tatctgtttt gacaaaagaa
    46261 gtcaaacggc agatggccga acaagtcaag gaagatccat ctaagtacta ttggactgag
    46321 caagatattc aagaagggac gatagaaaaa ccaacacttg ttacgcctac acgaagtttt
    46381 tatttgaaca aagagcatca attagttttg actttttctc aatacgaaat tgctcctggt
    46441 tatatgggta caccagaatt tgtcattcct aagtccgtga caaaaacgat tttggcatcg
    46501 gaagattatt tggatcatta gacgagaagt agttgcgact agcagtttca attttcaagt
    46561 aagtacaagt aaataataag aagagaaaaa gagaaagaag agatatagtg aaaagaaatt
    46621 atttagtcat cagtattatt gctttatccg tgcttttgtt tttcgaaatt acttcggtgg
    46681 cctccttgat caccgaagta aaaggacaaa cacactcttc ggagcattcg tcacaatctt
    46741 tcaaacaatc agaacaatca accattaaaa gccaatcaac tgaaacagct aacgtcaaag
    46801 aagccattca agaatcagcg gaaaaggtac aaagtcaatc atcacaatca acacaagaca
    46861 gtacagaagc aatccaagac ccgactgtca aaagcgtcgc aatcagcttt gatgatggac
    46921 caggagcgac cacaacgccg cagcttctgc gaatcttaaa agaaaaaaac gtgcatgtca
    46981 cttttttcgt cttaggagaa aatacggcgc agcatcctga aatcgtgaag cagacagctg
    47041 aagcagggca cgagattggc aatcacacat acgatcatca gaatctggcc actctttctg
    47101 cccagtcgat gacggaggaa gtgacgaaag cagacactga gatcaaaaaa agtcactggc
    47161 aaaacccccg cttttgttcg tccgccctat ggttctgtca cgaatgtagg agcaacgatc
    47221 atccagcgac cgatcatcga atggtctgtt gattcagaag attggaagac aaggaatcct
    47281 gatttgattt tgcagaagat ccaagcaaca gtatacgatg ggtcaattat tttattccat
    47341 gatatctatc ctgaaacgat tcgtgccgtt cctcaagtga tcgattatct gaaagagcaa
    47401 ggctatcgca tcacgacagt tagcgattta ttagggcatc caacggctgt cgagaactat
    47461 tatggcagaa acgatcatcg gccagttcag taagtgagac aagtatcttt aataaataac
    47521 acattttaat aagtagttga acacataact accttacttg caaaggctta a
//
LOCUS       DAFBSV010000009        44551 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.009, whole genome shotgun sequence.
ACCESSION   DAFBSV010000009 DAFBSV010000000
VERSION     DAFBSV010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44551
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.009"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(192..662)
                     /locus_tag="LLB18_000547"
     CDS             complement(192..662)
                     /locus_tag="LLB18_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HBK5243575.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGIFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            992..2632
                     /locus_tag="LLB18_000548"
     CDS             992..2632
                     /locus_tag="LLB18_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HBK5243576.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            2786..4108
                     /locus_tag="LLB18_000549"
     CDS             2786..4108
                     /locus_tag="LLB18_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HBK5243577.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFWDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(4176..4610)
                     /locus_tag="LLB18_000550"
     CDS             complement(4176..4610)
                     /locus_tag="LLB18_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5243578.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEE
                     AKKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(4675..5511)
                     /locus_tag="LLB18_000551"
     CDS             complement(4675..5511)
                     /locus_tag="LLB18_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBK5243579.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            complement(6253..6879)
                     /locus_tag="LLB18_000552"
     CDS             complement(6253..6879)
                     /locus_tag="LLB18_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243580.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            complement(7174..7509)
                     /locus_tag="LLB18_000553"
     CDS             complement(7174..7509)
                     /locus_tag="LLB18_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBK5243581.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            complement(7496..7780)
                     /locus_tag="LLB18_000554"
     CDS             complement(7496..7780)
                     /locus_tag="LLB18_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBK5243582.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            complement(7836..9359)
                     /locus_tag="LLB18_000555"
     CDS             complement(7836..9359)
                     /locus_tag="LLB18_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBK5243583.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            complement(9352..10527)
                     /locus_tag="LLB18_000556"
     CDS             complement(9352..10527)
                     /locus_tag="LLB18_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBK5243584.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            complement(10531..10716)
                     /locus_tag="LLB18_000557"
     CDS             complement(10531..10716)
                     /locus_tag="LLB18_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243585.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            complement(10682..12376)
                     /locus_tag="LLB18_000558"
     CDS             complement(10682..12376)
                     /locus_tag="LLB18_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBK5243586.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            complement(12373..12846)
                     /locus_tag="LLB18_000559"
     CDS             complement(12373..12846)
                     /locus_tag="LLB18_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HBK5243587.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            complement(12915..13070)
                     /locus_tag="LLB18_000560"
     CDS             complement(12915..13070)
                     /locus_tag="LLB18_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HBK5243588.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            complement(13204..13584)
                     /locus_tag="LLB18_000561"
     CDS             complement(13204..13584)
                     /locus_tag="LLB18_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBK5243589.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            complement(13588..13803)
                     /locus_tag="LLB18_000562"
     CDS             complement(13588..13803)
                     /locus_tag="LLB18_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243590.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            complement(13806..14213)
                     /locus_tag="LLB18_000563"
     CDS             complement(13806..14213)
                     /locus_tag="LLB18_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HBK5243591.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            complement(14479..15954)
                     /locus_tag="LLB18_000564"
     CDS             complement(14479..15954)
                     /locus_tag="LLB18_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HBK5243592.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            complement(15944..16792)
                     /locus_tag="LLB18_000565"
     CDS             complement(15944..16792)
                     /locus_tag="LLB18_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HBK5243593.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            complement(16829..17191)
                     /locus_tag="LLB18_000566"
     CDS             complement(16829..17191)
                     /locus_tag="LLB18_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243594.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            complement(17192..17350)
                     /locus_tag="LLB18_000567"
     CDS             complement(17192..17350)
                     /locus_tag="LLB18_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243595.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            complement(17491..18115)
                     /locus_tag="LLB18_000568"
                     /pseudo
     CDS             complement(17491..18115)
                     /locus_tag="LLB18_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            complement(18112..18423)
                     /locus_tag="LLB18_000569"
     CDS             complement(18112..18423)
                     /locus_tag="LLB18_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243596.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            complement(18467..18760)
                     /locus_tag="LLB18_000570"
     CDS             complement(18467..18760)
                     /locus_tag="LLB18_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243597.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            18954..19601
                     /locus_tag="LLB18_000571"
     CDS             18954..19601
                     /locus_tag="LLB18_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5243598.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            19662..20807
                     /locus_tag="LLB18_000572"
     CDS             19662..20807
                     /locus_tag="LLB18_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBK5243599.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(20888..21193)
                     /locus_tag="LLB18_000573"
     CDS             complement(20888..21193)
                     /locus_tag="LLB18_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBK5243600.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(21218..21649)
                     /gene="ruvX"
                     /locus_tag="LLB18_000574"
     CDS             complement(21218..21649)
                     /gene="ruvX"
                     /locus_tag="LLB18_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBK5243601.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(21646..21912)
                     /locus_tag="LLB18_000575"
     CDS             complement(21646..21912)
                     /locus_tag="LLB18_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBK5243602.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(22167..22892)
                     /locus_tag="LLB18_000576"
     CDS             complement(22167..22892)
                     /locus_tag="LLB18_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBK5243603.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(23253..23323)
                     /locus_tag="LLB18_000577"
     tRNA            complement(23253..23323)
                     /locus_tag="LLB18_000577"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23289..23291),aa:Gly,seq:ccc)
     gene            23440..24192
                     /locus_tag="LLB18_000578"
     CDS             23440..24192
                     /locus_tag="LLB18_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBK5243604.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            24208..24687
                     /locus_tag="LLB18_000579"
     CDS             24208..24687
                     /locus_tag="LLB18_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBK5243605.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(24938..26518)
                     /locus_tag="LLB18_000580"
     CDS             complement(24938..26518)
                     /locus_tag="LLB18_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HBK5243606.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(26511..27254)
                     /locus_tag="LLB18_000581"
     CDS             complement(26511..27254)
                     /locus_tag="LLB18_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5243607.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(27430..28206)
                     /locus_tag="LLB18_000582"
     CDS             complement(27430..28206)
                     /locus_tag="LLB18_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5243608.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(28454..29290)
                     /locus_tag="LLB18_000583"
     CDS             complement(28454..29290)
                     /locus_tag="LLB18_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HBK5243609.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(29301..30230)
                     /locus_tag="LLB18_000584"
     CDS             complement(29301..30230)
                     /locus_tag="LLB18_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBK5243610.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            30422..30775
                     /locus_tag="LLB18_000585"
     CDS             30422..30775
                     /locus_tag="LLB18_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBK5243611.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(30849..31505)
                     /locus_tag="LLB18_000586"
     CDS             complement(30849..31505)
                     /locus_tag="LLB18_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBK5243612.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            31731..33665
                     /locus_tag="LLB18_000587"
     CDS             31731..33665
                     /locus_tag="LLB18_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBK5243613.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(33751..34974)
                     /locus_tag="LLB18_000588"
     CDS             complement(33751..34974)
                     /locus_tag="LLB18_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBK5243614.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(34968..36866)
                     /locus_tag="LLB18_000589"
     CDS             complement(34968..36866)
                     /locus_tag="LLB18_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HBK5243615.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(36860..37978)
                     /locus_tag="LLB18_000590"
     CDS             complement(36860..37978)
                     /locus_tag="LLB18_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBK5243616.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(38061..38894)
                     /locus_tag="LLB18_000591"
     CDS             complement(38061..38894)
                     /locus_tag="LLB18_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBK5243617.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(38887..39804)
                     /locus_tag="LLB18_000592"
     CDS             complement(38887..39804)
                     /locus_tag="LLB18_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK5243618.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(40031..41155)
                     /locus_tag="LLB18_000593"
     CDS             complement(40031..41155)
                     /locus_tag="LLB18_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBK5243619.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            41338..42246
                     /locus_tag="LLB18_000594"
     CDS             41338..42246
                     /locus_tag="LLB18_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5243620.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            42387..44000
                     /locus_tag="LLB18_000595"
     CDS             42387..44000
                     /locus_tag="LLB18_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBK5243621.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT        13463 a         8879 c         7429 g        14780 t
ORIGIN      
        1 tgacttcaca gtctcttcct taaacggtgt tcaaaaactt gcatctgcgg taataagccc
       61 aaccaaacga aaaataggag gagctatttt tgtttggctg ttcttattac ttgatgcagg
      121 gcaggttttt cacgacctct gattcacggt gtttcttttt catcaacatt tttacgaaat
      181 actgtggaag actattgaaa taagtgtgga ttgtttcttt gtgtttcaat cgtttcttgc
      241 cattcttcat ttaattttgg attaccgttt tcttccttga actcataagg tcctaattca
      301 aaaatcccag acagtatttg attcacgatt tcatatagtt cagtgtgatc agacacatga
      361 ttcttgaaga tcatctcatt atcaccacgt ttgaacctca cattcgggct ctcatgatga
      421 acctctatgc atttttctcc tttttttaac tgacggactt ctgaaaacat ctcataaata
      481 tcttctccag taaaaccttc agcaagcgcc agactgtcca caagaccgcc tactgtcagt
      541 tcagagatta ttgcttgatt ggaatctaat tttaatgtat agcttgtcgc ttctactacg
      601 ccacatgcat tgcaaccgcc ttctgatagt tcgctttttc taatcaattg aacttctttc
      661 attttctctt cctcctctta attttctact tatgtatttt tatcacctga cataggtgac
      721 tcctatcaac gctatcatgt gcttttttcc tcagaaatcc tatttatcca ttccatctat
      781 cccttattct tctacttttc tttctctagc atataagaga tacgcatagt attcaagcaa
      841 ggattgtcga tataaaaaga acaaatactg ctattttgat ttcttttggc tatattacat
      901 ataaataaaa tttatcatac ctgctctttt tgactatatc atcatctgac ttctatactt
      961 cgtttgtatt aaaacttagg aggaatcatt catgcttaca gggttaaact tattaaataa
     1021 tccttttcta aataaaggaa cagcttttac aaaagaagaa cgggcaaaat atggaatcac
     1081 tggtatgctt ccaagtactg tccaaacact ggaacaacaa tctgttcaag cttatggtca
     1141 atacttaagc aaacaaacag atttggaaaa acgtatcttc ttaatgaatc tattcaatac
     1201 gaatcggaca ttgttttata aattgatggg cgaacattta gttgaattca tgcctgtcgt
     1261 ttatgatcct gtcgttgcgg attcaatcga acaatacaac gaaattttct tgaaaccgca
     1321 agatgctgca tttctttcaa tcgacgaacc agaaaacatc aaagcaagtt tgaagaacgc
     1381 ggcagatgga cgagacattc gtttgattgt tgtgactgat gcagaaggaa tcttaggtat
     1441 gggcgactgg ggtgtgaacg gtgttgacat cgctatcggc aaattgatgg tctatactgc
     1501 tgctgctggt attaatccag cacaagtttt gcctgtatcg atcgacgctg gtactaataa
     1561 tgaagaatta ttgaataatc ccttatactt aggcaatcgt catgctcgtg tagaaggcga
     1621 aacttactat gaattcatcg atcaattcgt tcaatcagct accgaattat tcccagaatt
     1681 gttattgcat tgggaagatt ttggacgagg aaatgctgca gcgatcttag aaaaatacga
     1741 agatcaaatc actactttca acgacgatat ccaaggtaca ggaattgttg tcctagcagg
     1801 tgtattaggc ggattgaata tatccggtga acaattgaaa gatcaaataa ttttgacatt
     1861 tggtgctggt actgctggtg tgggtatcgc aaacatcctt ttagatgaga tgatccgtca
     1921 aggtgtacct gaagaagaag cacgccaaca tttctatcaa gtagataaac aaggtttatt
     1981 gtttgaagat acagaaggat tgactcctgg tcaaatccca ttcgctcgca aacgctcaga
     2041 tttcactaat gctgatgaat tgacaaactt agaagcagtt gtaaaagcga tccatccgac
     2101 aatcatgatt ggtacttcta cccaacctgg agcattcact gaagaaatcg tgaaagaaat
     2161 ggctgctcat acaccacgtc cgatcatcat gcctttgtct aatccaacaa aattggcaga
     2221 agcaaaagca aaagatttaa tagaatggac ggacggaaaa gcattagttg gaacaggtat
     2281 ccctgctgct gatgttgaat ataatggtgt aacttaccaa atcggtcaag caaataatgc
     2341 tttgatgtac ccaggtttag gacttggttt gattgcttca acagctacac gagtaaatgc
     2401 tgaaatcatt tctcaagcta gtcgagcatt aggcggaatc gttgatgtaa caaaaccagg
     2461 agcagctatc ttgcctccag tagcaaaaat cactgaattt tctcaaacga ttgctgaaac
     2521 tgtcgcaaaa tcagttgtcg cacaaaactt gaatcgtgaa gaaatcacgg atatcaaaga
     2581 agcagttgaa tctgctaaat gggttcctga atataaatct ttagaagatt aagatcgtta
     2641 tagtaaaaga acatacagaa actttgtatg acgtctaaaa agaaaaaagc gactgcggca
     2701 aaacagcggc cagccaactc ctgctctttt gtcgcttttc tttggctttt ttcatatgat
     2761 acagaataag aaaggatctg taaaaatggc acaaaaaaca acaactgcaa ctgcagttga
     2821 ggaaaagaaa aaagaaggtt tttggtccac aaaaatcacc ggcgtaagtt tgccacttta
     2881 tttgatcatg gtccttgtcc tgatcattgc aatggcttta gggaaattac cgacgaatat
     2941 gattggacca atcgcagttt tggttatttt cggtaattta tttcatttta tcgggacaaa
     3001 aatccctatc gtcaaaagtt atttgggtgg tggttccgtt tttgcgatct tcgcttctgc
     3061 tgcgattgct acatttggga tcttacctga atatgtagtg aaatccacag aaaactttgt
     3121 cagcaatatg ggcttttggg acttttatat tgctgccttg attactggta gcatccttgg
     3181 tatgaaccgt aatctattga tgaaagcttc tgttcgtttt attcccgttg cacttatttc
     3241 aatggtcgtc tccttttttg ccgtaggact cgtgggcatg cttatcggaa atggttttgc
     3301 aaattccgtt ttatacatct cattacctgc gatggctggt ggtgttggag ccggagccgt
     3361 tcctttatca acgatttatg caaatgtttt aggtacggat gcttcttcta tcatttcccg
     3421 cctgattcct gcgacagcaa tgacaaatgt cttagctatc atcggtgcag cattagttgc
     3481 tcgtgctgga caatcaatgc caaaattcaa cggcaatggt aaattaatgg aaaaaggcga
     3541 tcttggcgat ggaaaacctc gaactgtgaa accttccatt ccacagttag gtgttggttt
     3601 gatggtatca ttgactttct tcatcttagg acaaattggt aactattttg ttcctaaagt
     3661 ccatgcttac gcatttatga ttattatcgt tgtcatctgt aaaatcgcca acctattacc
     3721 agagtattat gaagatgcag ctatcatgtt caataacttg attgtcaaaa acttgacagc
     3781 agctgttctt gccggtatcg gtattgcgtt gctgaatctg aatgtattag cttctgcttt
     3841 gacatggcaa tttgttgtct tatgtctgac aagtgttatc gcgatttcag ttgtttcagg
     3901 atttgtcggt cgtttgtttg gtttatatcc aattgaatca actattactg ctggcttatg
     3961 caacaactcg atgggcggaa caggaaatgt agccgtctta tctgcagcta atcggatgga
     4021 acttattgct tttgctcaaa tgggcaatcg acttggtggt gccatcgttt tgatcatctc
     4081 tggtttcttg atgcaattac tttcttagtc aaaaaaacaa aaatacctga tcatcaagta
     4141 tcggcttggt gatcgggtat ttttttgata aagatttaca ggattttcaa aaatcttttt
     4201 tgcattttat cggaatgata accgatgtgt tcataaaatt ggtgtgcttc tactctgtat
     4261 tctgcagaat taagccttat tgtcgttatt cctcgttttt tcgcttcttc ttctacgcca
     4321 gtcatcaaag cctttccgat gcctcttttt tcagcatatt tagacacagc aagtgccata
     4381 atattgaaca ttggatcgct aaaaatcgat tcataggact ccgcttgtac atagccagct
     4441 gcttttttag aagtaggatc ttcataaacc aagaaaaaat ttttctctgg ctccttcagc
     4501 agtttcttca tttgtctcac cgtaacggtt aatggtatat cataccctaa ttgatccgca
     4561 ttgatttcac gtagtgcttc tgcatcttct aaacgcattt cccgtaacat ccaaatcacc
     4621 agccaatttc tgatttttta aaatgaattt ttttatcata gtatactctt tttttcattt
     4681 agaacaatat gtttcagtga ttttgacttg cgttagtcta gattctccta atgtttgtaa
     4741 gatgacaaag gcattgtaac aattgaccaa aagaaccacg aggacaatta cttgaaaaat
     4801 aaaggtcact ttttttggag acaaaaccct gctaaatctt gctccccaca aacctccaat
     4861 aacagcagcg gggataacat aaaacaacat agataaatca aagcgcataa agctacttgt
     4921 taaagcaatc gttaccaatt ttgccagttg agaaaagaaa atcgtagata gagaatatag
     4981 tgttgcttct tttattggca atgcaaacat cagcatcaac aaagaaacat tgactggtcc
     5041 accaccaata cctaaaaaac tagctaaaaa gcccagaacc cccccacata taaggtacca
     5101 agtccatgac gtcaaatgaa attttggctg atgatgcttg gtgtagaaga acgcaaaaac
     5161 caaggtcaat accgtcaaaa aaatttggat cagctgcaca tgcttctcgt tttcaaataa
     5221 ctgtaaaaaa acttcgaata caatgttgcc gactactcct ccaacaacag ctccactaga
     5281 tacccaaccg acaatctgcc aattcagtga tttcccgctt gatacttgtc gcacagtcga
     5341 aacaatggac atcgtgaata ccgcaactgt tgagtaaaaa gaaatccctg caacagaatg
     5401 ggcgccgata agatcaagaa tcggtttgat caacacgcct ccacccatcc cggaaatagc
     5461 gccaactgtg ttcgccagaa cgatcaccac aaaataaatc agaccaatca tcttgtattt
     5521 cctttctctt gtttatatct tttagcgatt gttactcttt tcttttatta tacagtaaaa
     5581 gaaacaaacg aggcttcgaa agcttttcta ctttttaagg aaatttagtg ctaaacgaaa
     5641 agaggttgtg aaaaagctgt cctgcatcaa gtaataagaa cagccaaaca aaaatagctc
     5701 ctcataattt tcgtttggtt gaacttatta ccgcagatgc aagcttttga acaccgttta
     5761 agaaagaggt cgtgagcctg ccgttcagct ccgagtcaca aggaacaatt tcaaaaaaca
     5821 gcttctcatg tttgttgaat attgtgactt gtgaccgagg agttggcagg agaacaccgt
     5881 ttaaggaaga gactgtgaag tcaacgtttt gacctgatta ttagagaaac aaatggcaaa
     5941 atagttcttc atatttcgcc gtttttcgag cgaatgccga ggggcagctg attgaacatc
     6001 gtttatttgg aaaaagggat tgtgacaaga cgtttgtcac aatccctttt tttatatctt
     6061 attaattcat tcttttgttc tattcttctt cttccgccat gaatgagaaa cccatatcaa
     6121 agaactataa aggttatcaa aacagcgttt atgactaaat gaattagagt tatctatcac
     6181 tatttttcaa gcgatttaaa ccaaatggca tacaatatgg catacaaaaa cttcaataag
     6241 ccgtgggggt ttttaaattt cttcttgttc tttaaaatca atgagtggag ctacataatt
     6301 tgaatccact ttttcaaacg tcactttttg catcgacgaa tgttttcttt cccaagataa
     6361 cgtaaataga tttgactctg gacttataaa gtctacttca ccttctagta ttactttctt
     6421 atgcaaatat tcctctaata aatatagact tgctaaagca tacaacacat tttccaaatt
     6481 tgcttcctta taatttgaag aacgaccatg ttttactctg ttatatattt tccaccaatc
     6541 tggtgtatct tcaggccacc catctccaaa aggttttagt gaagtcaatg ttaaagaatt
     6601 cataacccta acaccattat ccaaacacat taattcgcta gatttaataa cagctttaaa
     6661 atcagttatg cttttattgc tactgctatc aaatccgcaa agttctttga aaataatctc
     6721 acactccgaa ccaatcgcta gtagtagttt ttgatattca atagagaatg ttttgaaatt
     6781 attctcatcg agcatcacaa aatctgtggt attaataaac tcattttcta aatgtagata
     6841 atacttccaa taaaaatttg taaactctgc tttgtccatt aaatcacctc ttttgaatta
     6901 taacaaaaaa aacacgtcca caacagacgt gttctttgat ttctacacaa tcagcttgcc
     6961 aaaaccatcc aatcagtcct agcatgcctg tattaaaatt gaacgttcat catctatcat
     7021 ctttcttagt ccagcatgtt tgcaaccaca cctacaattt tcagtccaac aatagatttc
     7081 gactagctaa gtcttgcaaa attcaggcag ctaacccttc atttactacc ttaattatac
     7141 taaataccca caacgtttac aagtgtaatc attctaagaa atctgtttag ctatgatcgt
     7201 tgtataatct ttaaacgccg ttccttcatt gattgaaata attttataac tcttgttttt
     7261 ccaagctact ttcatatcgt ttgttagttc ataatcttga tcgtatcgaa taataaacgt
     7321 caacgttcct tcaagaatgg tacctacact agcaagcacg tcttttagca tttgtgaacg
     7381 cacattagcc caacattcaa atacagtttc ttcactatcc accatctgcc catcttcatc
     7441 ttttacccgt tttgtctttt taaacttgac tctctcagtc aattcattta cattcttaat
     7501 gattggcata ataagcacct ctcatttgtt gtactaatgc ttgtaccgtt actggtatcc
     7561 gttcgctgct ggcttcttga cggttcaaat accaatgttg agtaagtaat gacaccgcca
     7621 aatcaaattg ctgataatta tccatatctt tatccgttgc gctactatca atagcacttt
     7681 ttatatattc gcctgctgta tcaatcaatt gttgaataaa gtcatcatca atagtgtgat
     7741 cgatccgcat actttttttt atgctatcca aaattaccat tttatctctc ctaatgaaaa
     7801 aaaggcagtg ggataaaccg ccgcccaata tttttctata cttttggtgt tacaactggc
     7861 gtaaactcaa tatacactga agcattttga tcaattttct tataatcgtt gcgaacgatc
     7921 actgcaagtc cttgtgagta gtaatcgaat ttttcccatt gagtcgttac ttgatttcta
     7981 cgagcaacaa agatagattg tgcaatatcc cccataatca tagggaatgt tccagcttta
     8041 ggattggcaa acaatgtatc tgcaatcaat actactggca taccgaataa tgatttacca
     8101 ctaggtgctg tcacatcggg ttgtaaaatg taacgtccat ctgaatcttt caatgtatct
     8161 aggtggtaat atccgctttg gtttagaatt accattttat ttaatgctgg gtctaatgcc
     8221 acattgtata gttgtttcaa atcgtccaac gtagcagccg ttttcttagt gaatgttttt
     8281 aataaatcca tgatatgctt attgtcagtg ttttctacca atttcgctaa ctgatctttg
     8341 acctcttgta caatattcac tgctgaatct tccacaacct catttgataa ggcaatctta
     8401 ccagcacgag tttctacttt ataatcaact gaagtaaaca tttcagcgtc aatatcacca
     8461 atttcagcaa gttcagcttt tgttgctaac actgcttgtt ggttagttgc tactggatat
     8521 ttaccttgtc catttgatac tgtttttact gttgcatatt gagctaagtt ataatttgaa
     8581 cgtttcaaat caaagacttc accgattact tcttcgggaa caactgccgc tgcatttaca
     8641 gtagtgactc catcacgcac ttcgccttgt gaacggatat attcttcata cccacgcaat
     8701 tctgtttttt cgttatcgat taaagttttt tccatgttat tactctcctt ttgtgcttta
     8761 gaagtggatt ctaagctatt gtttgtttgt tttgcttggt tgttactcat aaacgattcg
     8821 taagaacgct tatttacttg gacatttgat gaatcataag cgggaacggt cacgacacta
     8881 atttcattaa gtgctttgat tttatctatt gatcgttcaa ttgtgccatc ttcttttttg
     8941 tcgaatgaat ctaatccaag cacgaaccca aaggacatag aatcaacaac cccttttgag
     9001 atattctcat acacatcatt tgaataggtc gtgtcggtta gctctgcttc aaaatgtaat
     9061 cctgtatcat cgacattcaa tttcaacgta cctgctttga cactagctag tggctttgaa
     9121 taatcgtgtc catataataa gaacacattt gataaatcca cctcttttaa tgcttcgggt
     9181 gtaatcactt ctacaaagcc gcctaaatct tttgacggtt gcccgaattt caacgcatag
     9241 cctgaaatag ttttgccgtc tgttggttgt ttttcatttt ctttctctac tttgggagaa
     9301 tcggctgtta gctcagcttc ttctgtcagc cgtttttcct tttcttcttc attattcaac
     9361 tggtgtaact ccttcctgtt cttttaattg atatttctcc aacgtatcta aatacgtaaa
     9421 gttcaaactt gctagtaaac gatcgccacc atccatgggg ggtagcccca ttttcgaccg
     9481 cccctcatta atcgtgagaa gtgacccttt gacctgatcc aatacatttt ttacttttgt
     9541 ttcaggatca gtctctagta actgatcgga attaaagcgg atattggttt caagtttcgt
     9601 atctaattca ctcacaaaca cattaaagta atgaatcagc gtactttgga tatactggag
     9661 attactttga acggtgctag aatgttcatt ttcaacgcct aaacgctcaa tcggtacacc
     9721 aaacgccttg gcaatttgtt ttgtgttcca atcattggaa ttgataagct tcaaaacatc
     9781 ggtgtttatt tctaatgttt tgtagtccat tgtttcatca agaatgatcg ttctaagagc
     9841 attatctcca ctacttgaac cgttggcttc ttcaaacttt tcacgaattg cgttctttgc
     9901 tgatccgtct aaatctgact tatgaacctt caaaatacct gacccactga caccacgagt
     9961 aaagaaattg tgcaatgtgc ggttgccagc ttgttgaatt ttcagttcat cacgtaacgc
    10021 ataaagtggt ggtaatcctg ttaaaccatc ttgggtgaaa tatttgaagt gcaaaatatc
    10081 gctagacttc acacgtcttt ttttatcacc aatctgataa gacaacgtac cattatctaa
    10141 ttgagtaacc gttacacttg agttaggtaa taagtgaatt tcttctacct tttcaccgtt
    10201 gcgtttaatc tctgcaaagc tattaccgtt tagcaacata ttgaccgcca aagcaaactt
    10261 taaatgccaa ccatccattt ctgaattagg tttctcgttt agtaacttca ccagttcatt
    10321 atcagcttgt ggcatattgt ttttgaccaa ttgaatcgga cttgaagcaa tatcactagc
    10381 aataattcga acggctgcaa acacatcact atttcttaat gcacgaacgc ttgtaaagct
    10441 ggtggtgtaa tcatccgatt ggattgatac cacatgttgt aggaaaggat ctcccgttgt
    10501 attttgtctc gctttaaaaa atgccatctt ttaacctccc ttctgttctg tatttagcat
    10561 gaccgctacc ccaataagca ctatgcccag cgctaacaag ccatagtaga catttgttag
    10621 taaggtgata gcaaccaaca cacacaccaa tccaagaagt aaaagaacgg tatgaatgta
    10681 attagaaaga aaattcttca cttgtataaa attcattgtc tgctttcgct ccttccgttg
    10741 tggtgaagta atccattgca aacacatagg cattgattaa tgcagctatt ggatcaattt
    10801 tgttactgtt ctttgattta ttaatctgaa tgccgttgtt atccgttttt aaaatagcgt
    10861 tgttcactgc atgggtgaga atcgtatttt tattgtgaat aacgttgcct tcataaactt
    10921 gttctctaaa agttcgggtc ggaacgttta gagtaatcgt tccttgtctt acttctaaca
    10981 ttgggtagtt ggctttttca gctttactga taagcgaatt agcgttatac gggtcataac
    11041 aaatccccat acattccaaa tcattttctt gaatcaaatc ttgaataaac tgaaatactt
    11101 ggtcatagtc cacgattcca ctttctaatt gagtaatgga acactcacca gctttttcta
    11161 gttctcgata aggcaaaccg tcgcgctttt ctttgtcttg aagcccatat ttggtggcta
    11221 caaagctatg tgaatcacaa taaagttcgc cgttatctag cggtacgatc catgaaacgc
    11281 tagttaaatc atctgtttta gataaatcca ctccgatata aacgggcttg cctgtaatat
    11341 cttgtggttc tacttcggtt gcctgccagt cttcagcaat catatagctg tcctcactcg
    11401 cttgtctcca taaattgaag tttttcacca atacagaatt aaggttattt tgtttcaaag
    11461 caaggttcac atcatcttga atggttggaa tcattacttt tttgatttct tcactttcaa
    11521 aaatcggatt ggctttgatc catttctctt gatcgtgaat ttcttcggga tcgtccaatt
    11581 cccatatcgc tataaagtac ctgtcggctt gttcttcgcc ttttagcaca cgatctaaca
    11641 ataagtattc ctcgtacata ggaacgttta aatcaagccc agcggtacta ataacacaca
    11701 ataagccgtt cttttgttgg gtcattcctg acttaatgac gttgtacgtt ttacgagttt
    11761 ttgcttcgtg ccactcgtca agaattgcgg ttgttggtgc aaacccatct agcgtgctgg
    11821 tttcactagc cagtgccata gcgaacgaat tagagggcaa gtgctgaatc ttagagttca
    11881 taattttcag ttgtggtctt aaaaacttac tagacttgac cacgtttcta agtgaattag
    11941 acagcatatc atagcccaat ttagcttgtt tcaaagcgtt acttacaaac aatacttgcc
    12001 ttgcttctgc tggttcttgt tccataatca acgcattggc agccatgcca cttgcgatat
    12061 acgttttccc attcttacgg ctcatactgg taaacgctcg attgaatcgc ctgtaattcc
    12121 cttctttagt acgccagcca taaagactgc ctagaatgaa tttttgaaat cctaacatct
    12181 tgattgcttt accgtccgta gatggtagca actcaatgaa tttaatcgct ttggtggctt
    12241 gttcttcatc gaacacataa gggaagctat ctgacttaga acgctccaaa tcgcttatat
    12301 gacgctcaca cgcttggata attttcttgg gtgcaatcag cttacctgat aggactttct
    12361 caatgtaatc attcatgaat tcatcaactc tttgaacggg tcttcgggtt catcattttt
    12421 aaccttgttc aaagctagtt ttgatcgtga ttctaaggtc atacctagtg aggtggcttg
    12481 ttttttcaaa tcactcatag cttgtgattg aacccgaacc gctggattgg ctttctttac
    12541 tccgttttcg catgtgataa acgtacctga ttttcttatc tcggcttcgg ctgttttcat
    12601 tcgagcaaag gctaaacaat aggctaccaa tgaaccataa tctgcttcac tcaatggata
    12661 atcttttttt aatgttggta cgatacgatt ccattcactt ctagcgctcg ctgccatcca
    12721 gtcagggggc gtgatattta ttaatggttg ctgcttgaac aattcttctc tagcgtccac
    12781 acggattgct ttttcttcac ttgatatatt gccttttgta tcgtgtaata ttttagggtg
    12841 tcccatgttg tcctcctttc agacaaaaga aaaaggaacg taagcaatta agctcacatt
    12901 ccttcgtttt tcgatcagaa tttttcttta tctaatttat ctatataaat gatttttccg
    12961 ttctgcattt gaatggtcac ttgaccaaaa tgaggtaact caatggtgcg ctgtttccct
    13021 gttttatcag taataacaat tgtatttttc aataaatctc ctactttcat tatatacttt
    13081 ttcacttgtg attacaagtg taatcgttat ttgtaattac ccttatgcct tttcacaacg
    13141 gttatttgta ccaaaatgag taggcatcga ttgtcagtaa gtttcacact atgccccctt
    13201 aactcaaagg gtactctttt ctcgtctttg tctttcattg gctgtcttgg aattatggtg
    13261 tgcatggcat aaagaacgaa aattagtttc atctaaccgt ctattccaat catcttttag
    13321 ttcaattttg tgatctacaa catcagcttt ccttatcaag ccttcttcta ggcaatcctc
    13381 acatactgga tgatttaacc gatacaagta tgaagccttt cgccatgttc tactttgata
    13441 gaattgaaaa tatttacctt cgctttgctt tctttcttca cgcttaattg ccgtttgctt
    13501 tgctttatgc ttcccacaat acttctgcct ataatcaatc aatgttttac atccagcatg
    13561 attacattgt tttttaactg ccatagatta ccaaccaaag cgatctcgtt cgtcagaatc
    13621 atcttgttcc cattttgatt tgtattcaat ataaggcgaa actatcttca agcacgttcc
    13681 gtctttaaaa ttaactttag tgattttatc ttcctcaaaa ctaataaagt ctacatcttc
    13741 ttgagtgttt gaatactcaa tgtgtttctc accatcgaag tatctaatac tttccatatg
    13801 cataattatt ctacctccaa taaattagtt atcaattcat catctgttag tagcaaagcc
    13861 aagaacttat catggatgtt taaaaacaaa ttatcctcat tcgatgtaag ctctcgttgt
    13921 ctcgctcgat catataggtt aagcagacaa ttaaattcat ccattagctc acctgtatca
    13981 tcatagttgc cactatctac caatgatccc actactagcg attgacacca cgctactgac
    14041 tcctgcagcc aatcaggttc ttcttccatt atctttaata cttctggatc aaatgtggaa
    14101 taatcttctg ttaccaatcc cacactaaat gccagcgtgt tcattagaaa ccgatccatt
    14161 tcatctgtat attgaaagtt cggtgctttg tttgttgaaa taatattgag catttacttt
    14221 cctccttgat tcgtaacacg tggtaacacc tacgtaacag gtacccgtta ccactcaatc
    14281 ccaacgggga caagggttct agcgttttgg taacaggtaa cgggtaaaat ccagtaacat
    14341 tattccccag catattagct aactatttca aaagttttaa ggaaataagg tgttaccccg
    14401 ttaccaaatt gctgtatccc ttggggcagt aagggtaaac tagtaacggg ctaggtgtta
    14461 ctgacccgtt actacccgtt actttttgta ctttccagct cgatttttat tttcataggc
    14521 atttgactta ttgtaaaatc ctcgtcgttt atttcttttt ggcagttgct tccgttccca
    14581 accaggaata ctgctaataa tcaaggcaat ctttttagtt tctgcatctg atcgaccatt
    14641 caataaatcc tttgcttgtt tatcaaaaac agcttccaaa atatcagcgg tgagtacgct
    14701 atcaactaaa taaaactctt gttgcatagt agctccatta tagaaatgct gtaaattttt
    14761 ctcattacat ttactgtcag gatagttctg ataataagaa cgtctcgccc acgctggagc
    14821 ttcttcccat ttatacggga tttccatttc caaatattta gtgattgctt ctttaattgg
    14881 attctccatc ttggcatcct cttgatagtc ttttgcaatt tctaagactt ctttatcttc
    14941 atcgggacta aaatagattc gttgtccttt atcaaaaagc acctttgctt cagctaacac
    15001 ttgaagaaaa tattcatcct ttgttttaaa cggattcatc tttggcttat tcttacaagg
    15061 caaaggataa aaacggcggt ttcctgtatc atctttcaaa tactgcccat cattcgacgt
    15121 tccaataaat acacattgcc ttgcccaagc tatgacattc cgaccataag gaggtctaat
    15181 tttatcgatc ttggcactga tgaagttttt tatctgttca attttagttt tgttcattga
    15241 agataattct ccaagttcaa taattacatt gccttgaagc tgcatataat catctttctt
    15301 ttcacctagc gaatctaatg aatcggtgaa aaaatcatcc gtgtaaagta atgctggaac
    15361 ggtactctta ccaatccctt gcggtccatc caaaactgga acgatctcaa actttattcc
    15421 tggtttatag atacgtgcga ctgatccgac tatccaacgt tttgttactt ctcgtgtgta
    15481 aaggttgtcg tctaccccta aaaggtcaat aaacagtgtt tccagtctag gctgttgatc
    15541 ccatttaact ttttcgatac gttcttttac tgggttgaaa acattctttc tagccacatt
    15601 tactactgct ttgtgtattt tgttgtcatc aaaaactaca ttgtagtttt cttcaatata
    15661 tgccgttaag gcatcctcaa aactgtcttc ccattctcca gcggtacgat tgatccaagg
    15721 agaatctttt aataggtgaa tgtatccgct aaattcgtta taagcaattg ttccagctaa
    15781 attgctatca ttggttaaaa tcaattctgc attcacaaca ctgttacttt taatctgatc
    15841 gtctttattg catcttaatc gtgacatcca ggttttcaat tcaatgatat tgtcttcacg
    15901 ctcgctggct tcgggaaagt ctaaaatact atctaattta tgcttatgag ccatgagctt
    15961 tccccctcaa atctttttta atcatcgatc gaataatttg attcacttct ttatctttta
    16021 gcggtggttc attgtacgca tttgctgtat aaatcaattc tgctaaagtt tgattatcta
    16081 caccgtgcca tagtaaccaa ccgcataact tagttaaatg atcgtttcta ctaccttcgc
    16141 cagcgccttg aacaatcata tctaattttt ttgctgtccc tgtttttgct acgggtcggt
    16201 attgagtctt tatttcttgc ggttttttta gcagtaggtt cactagccaa tcgggagctg
    16261 gtgcaatatt atttagagat acgttttcaa taggttcata tgctctccca acacttcttg
    16321 aaataatcat agttggcgct attggaactc ctttagtgat aatatcaatc ccgcttaaac
    16381 ttttaccttt atcatcacgc ccgaagatat cagcaaatgc acctgtttct tgttggataa
    16441 ttacaccatc aggaatttta aagaagaaat ggattccttt acctggtgtg atttccgtat
    16501 aagtagaagg aaatggatca tacattgaag caagtttttt ataattctca acgccgtttc
    16561 gtgtttcaga atgttgatct aggtcaacta ccaccatttg atgatcttca agcattaacc
    16621 caatatttct agttgcatct tccgtccacc attcattaat ttgattagaa tcgttagttg
    16681 catcattcca accactagag ccttttattg gaattttagt tccaggagat aagggataaa
    16741 ttgaccatcc cgacttttgt aattccgttg ctgcttgata attatttgcc aataaacctc
    16801 tcctcctttt tcaaaatact ggtataaatc attcagacac ctccatgagc ttcaactgct
    16861 caagttcgta tttcaaccca tcccgaacaa attcagcacc ttttaattga ttctgatact
    16921 ttacccatgt attaaatgtt ttcacccttg cttcttgcat atcagtaatg tttaaccatg
    16981 cggttaaaat ctgatttttt agctcgttga tttctcgaca aattattttg tgttctgcat
    17041 gttttttgag tacatacaaa actgttagtt tttcattgaa tgaatttcca aagtaggttt
    17101 tcccgatatt attttctagt tcagcgatcc cttgattaat ttcctctaat tcaaggctat
    17161 cgagttggtt taatagtttt gttttgtaca tctacttatg ccctccagtt cttaattgat
    17221 agtcgtactc gtcataagca gtgaagagat ataacgctaa tcctgcaaag atagctattt
    17281 ttgcaattaa tggtaataag ccgaaaattc cgccgattaa aatgcttcct ataattaagt
    17341 ttcgtttcat aatggttccc tccgattttt taatatggta taatcggaac aaagaatatc
    17401 gggttttatc ccaattaagt tgcctttatc ctgtccgcca agactgttat ggataaggct
    17461 ttttctttgt tctcgatcat gttaatgctc ctaagttgtc tgcaattcag cagaacgatt
    17521 ataaattttc tcactcactg aaaactgcaa cccatatttt tctttaacag tcattaattc
    17581 tactgtctca tctaaaatag gttcacgatc aaccaacatt tcaggagtca tatctttctt
    17641 ttttaccatt ttggaatgac cataaatagt tgatacagct ttattggcta tcacattcgc
    17701 tttaatgtag tctactggtt ttggttcagt aatagcgtgg cttaatttag tcattgcttc
    17761 tttttggtgt tctttgtcta gcatgcggaa tacttgaaag ccttcaagtc ctgtggactg
    17821 gcgtagttct ttgatgatgt cgaaaatcca gtcttgaaat gcctcggctt cttttttacg
    17881 gcttttgaat gccatgcggt aaatattttt tttcgttgat gatgtttaca tcttgtgttc
    17941 tgcccaatga atcgatgacc ttactagtag taaccccatc tttaggcaaa gagtgaatgg
    18001 ctctagtaac ctgtttaaga cctaacgctt ccgcaacatc tttcgccact gcccaccatt
    18061 catcattaat atcgacaaat cttataatgt gtccgttcca aatttcagtt ttcattcaac
    18121 gtcctccagt tcaagcccta gcaagctcgc taacaactca acttgctgat acaaaatttc
    18181 ttgatactct tcaatagaaa gtcgttcttt aaactctgct tgtactaaat cgttcaagcc
    18241 acgcaatact ccgcttaccg ttggttcttg tggtagcaat ttttgatagt ccatttgttc
    18301 gtacaaacat tcaaacgttt cttctagcgc tttgccttcc aagtttgcta attctgccgc
    18361 tgtgtcttct gtaagaattg ttgataatac tttttcgatt gctttatttt gtgtcgattc
    18421 cattattatt tcctcctatt aatccctttg cccccacggc ttgcgtttat ttttggtatt
    18481 cttccataaa gcgatcacat tcatcttgtg aaattcttac gactccatca actataatca
    18541 actttaaacc gttaggaaca tatttctgca tcatagtatt gtatgaaacg ttcatatact
    18601 tagcagcttg tgccttgttc atatattttg gaaactggta ctttttttct aataatgaaa
    18661 gtaacgttcc ttgagtttgc tctacttgtt gaacaactcg atcgtcaata attttaaaag
    18721 ctggatcatc aagcgtgagt ttgtcaattt ttaattccat atttatcccc cctcgttagc
    18781 atacatttct atacaaagat tttaaaaaaa tgcaagaggc tcttgaatac atttctatac
    18841 ctcttataaa ctcaatatac catcatacct tttcatttgc aagaatttta acatactttt
    18901 ttgaactttt atgtttcaca catatttaaa tcgtgatata gtagagaaaa tatatgaatg
    18961 gtggtgaaaa tgtggctaga aaaaaatacc ccgaagcagt ggagacagga caaagaatta
    19021 gactggctag aattgaaaag ggactctcaa tggaacaact tggaggtaaa ttatccccac
    19081 cggccagtaa aggtgccgtt agtaattggg aaaatggcta taatcttccc aataacacca
    19141 ggcttaaaca actttcaaag gtattagatg tatccactac ctatctatta aacggatctt
    19201 atacattaag agatatgcat atgatgcccg aaattaagcg aaatgtgctt gaaaagcaat
    19261 tgaaaaaaac tattgaaaaa aataactcta taattgattc taatctttct aatgctatca
    19321 ataacatcga agaagataac ctgactgtct cacagaagat ttatttaaca aacgcaataa
    19381 aatatcttaa aacaggatct cgaattgaat ttcctgacgg gagtacccca attgcttatc
    19441 tcgcagctct tctaaatacg cttttacgat atgactcatt aattaatgat tcagaaaaaa
    19501 atacagatga gaaaaaagag tatcaagaat tttatgaaaa tgatcttcta aaagagttca
    19561 cagctcttgt tactgagcta aataaacact attcaaaata ataataaact gcctcctcca
    19621 accgccccca cggcttgcta cactatggag ggaaaactat tatggcaaca ttcaagcaat
    19681 atgaaactaa aaaaggtaaa ttttggctct atgaagccta tcttggaatg aacaaaatga
    19741 ctggcaaacc tgataaggtt cgtagacgag gttacaaaac aaaaaaagaa gcccagcttg
    19801 ccttgtcacg cttgcaagtg gactacgata aaaacggtat taaaaaagcg aacaacgaaa
    19861 cgtttaaaga agtttatgac ttgtggctag aaacatataa aaccactgtc cgagaagcca
    19921 ccttcatgaa aactgaaatc aagtttagaa agtggattct tccaaaatat ggaaatcttc
    19981 gtgtgaatga agtcacggta aaaaaagccc aacaaattgt aaatagctgg gctgaaacta
    20041 ctgaccaata caaggtactt cattcaactt ctaagcgtat ttttagctac gctatcaatc
    20101 ttgggattat tgagactaat ccactagaca acgtattaat gcctaaaaga accaccacta
    20161 agcataaaga aaaggtcaaa gtttacagta aagaacaact gatcaccttg tttgattacc
    20221 taaacagcaa acctgaaact tatcgaaacg actttgataa aacgttacta cgctttctct
    20281 tttatagcgg ggttaggatc agtgaagccc ttgcattgaa ttggtcagac attgattttc
    20341 aagaaaatac ggtcaccatc aataaaacac taagccaatc caaaaatggc tataaaatca
    20401 gtgatcctaa aactgattgt agtgctgggg ttcttccact agatgaaaga acaatttcta
    20461 tattaaaaaa atggcagatt aatcagcgga aatatatgct gacacttggt gtaactgatc
    20521 cgactatgat tttttgtggt atctataaag aactaatcac acaccacgct atttatgcaa
    20581 gattgattac tatttgtgaa aaagctatgg ttccatttct cggtgtgcat gtagcaagac
    20641 acactcatgc ttcaatgctc ttggacgctg gagctactat ggtagaagtt caaactagat
    20701 tacggcatac aaaaattagt cagacgatcg attgttacgg tcacttggca aaagaaacga
    20761 aagaaaagac tgttgaaaaa ttagtacaac acttaaatat tgactagatg gcatacaata
    20821 tggcatacag taaaaaataa aaaaaggaga aaccctatca tatcaaggtt tctcctagct
    20881 ttatagtcta ttcttcttct tccgccatga atgtattgaa tacttcttca atcatgtccc
    20941 attctgcgtc tgtttcgatt tgttctaact cgccttctgt tccatcttcg ttttcgatgt
    21001 atgcataagc ttgtaattct acatcttcat cttctgaaac accagcagga tataaaagaa
    21061 catagttacg tccaaattct tcttgtccgt caactgttag taggatttca tataatgttt
    21121 catttccttg gtcatccacc aatgtgatgt gttcgtgtcc ttcatggtcg tgggaatggt
    21181 tatgttctgt cataagatta cctcttttct tttattatta aaataattgc ttacctgagc
    21241 cgtctaaata attttgtaag atcatcacag ctgctaattt atcgatgact ttttttcgtt
    21301 tggctcttga agtatttgcc tgctctacta gcatacgttc tgcctgaaca gtggttaatc
    21361 gttcatcttg ataatcaact ggcaaggaga atagttcttt gatcttttct ccgtatgaca
    21421 tggaagcttc tgcccttggt ccgatggaat tgttcatatt tttaggtaat ccaactacaa
    21481 accggtctac ttcatattgt gctactaatt ccttcaaccg atcaaagcca aactcttctt
    21541 ctgcttcatt gatccgaatg atctctactc cttgagctgt ccagccaaag gggtcactga
    21601 tagcaacacc tactgtctta gaaccgacat ccaagcccat tactctcata aattcactcc
    21661 atgatttgag aggtagtcct tgacaattac ttccatgatc tcatcgcgtt cgtgacggcg
    21721 aatcaaattt cgagcatcac gataacgagg aatgtaggcc gggtctccag aaagcaagta
    21781 gccgacaatc tgattgattg gattgtagcc tttttcttcc aaagcccgat aaacaatcgc
    21841 taatgtttcg ctcacttctt ttttgcgact atcgtcaaaa ccaaaacgta cggtttcatc
    21901 tgtaaaaccc atgattctac acctctttcc cgcaaggtaa ttccagctta ccttctacaa
    21961 ccttatttta ctcgaagaaa gggaaaacta caaacaaata ttccaaactt ccgaataaat
    22021 taagaaacac tatttgtatg tttttttcct tttttctgta gctttatcaa aagtactctt
    22081 ttcataaagt atacgctata tttctttgaa tgtatgtttt tacacaattt tttcataata
    22141 ttcataaaaa attcgaatag ctgctactaa ttttttgttt ttgttgcttg tcctgtctca
    22201 taattgatcg tgtagccatc ttgaacattg tagataaaga cattgaattc aatttttttg
    22261 tcttcaatgc tttctgcttc caattgcact cccctggcta ccagttcatt cccctcaaaa
    22321 tgaggagtga cacggtagcg tacatgatga tttgtttctt tgatatatgc cgcaatatca
    22381 ttttcgtgag caagcatgta tggagcattc aacgaacgtg tccctgtcat caagttttta
    22441 atgttgttat tttgaccagt cagctggaaa ccaattaaat ggctgcgatt atataaccat
    22501 tgcccgtcac ttaatttctt ttgtttccaa cctgtcgggt caatatacaa aggctctctc
    22561 ttttcagtag ggaacaaatc ttttccaagc atagcattgg cttgtcctac tctgttcaat
    22621 ttatcaatat ttgaatagct ttcccatgtt cctttggaaa ggctaagatc ctcttttgta
    22681 aattccggct gattcccatt gatttctatt tcttgatgtt ttccatcata ttctggcaca
    22741 tccgctactt gagaagcttg tggtgtggaa tcaaaaatag ttgtaatctg ctgaaagata
    22801 tctgaatctt tttgtgtggt ggaaacaccg aatgcccctg caatcacagc agcgacgatc
    22861 cccacgatcg ccttggttgt ttttttgctc atttctttac tcctttacta acagctccct
    22921 aaatcttaac atatgttccc ctataaataa atactagaaa gaaatagaaa cagcaaaaaa
    22981 taaaacctgt tttaagatgg cttaaaaata caaaaaagag acggattcct cgtctctaat
    23041 cagtcaccac tctatctgta aggtatttat tattattcaa aaattttctt catactcaag
    23101 acaatacact gatttcacaa ccgcttggta aacggtgcgc aaaagcttgc atctgcggta
    23161 ataagtccat ccaagttaaa aacataagaa gttgtttttg cttggctgtt cttattactt
    23221 gttgcagagc agctttttca caacctattt taagcgggtg acgggaatcg aacccgcgac
    23281 atcagcttgg gaagctggga ttttaccact aaactacacc cgcaatacaa aaacagtata
    23341 cgcctctttt attccttcct caagtttttt tattctttac gcttctggta tgttttgtag
    23401 taaaataaaa ctaatcaatc aattattgga gaagatgcta tgacgggaaa agaattagat
    23461 ctgttgctgg acacttgttt actcgctggg aaaatcatga tggaaagcaa tgcggagatg
    23521 tatcgggtag aagatacgat gagtcgaatt gctttagctt ctggaaattt ccgtttggtc
    23581 agctatgtca ctcaaaccgg tctctttatt ggtcttgatc gtacctcgac catccgaatg
    23641 gaacaaatta ccaaccgttc gattaattta gaaaaagtag taaaagtaaa tgatctttca
    23701 cgtaaatatg ttgcttcaga gctaacatta gaagaacttt actgcgaact gcaagcaatc
    23761 gaccgagacc gttctttctt tcctgtctgg ttgcaaatcg ttagcgcggc agtgatcagt
    23821 ggaacaatta tggtgttatt tggcggaaag atgaccgatt tacctgtgac tttagtcatt
    23881 ggaggattgg gatacgcagc ttatctatat agtttgaaat tttttagaat caaattttta
    23941 tcggaatttt tatcttcttt attgattggc atagccgcta tctacagcgt acgttttggc
    24001 ttaggaagca atcaggatct aatcattatc ggatgtgtga tgcctttagt tcctggagtt
    24061 caaattacga acgctatccg tgatttgcta gctggacatt atgtctcagg agtttctcgc
    24121 ggaacagaag cgatgatgac tgctacgatg atcggttttg cgattgcttt tattttccag
    24181 cttttttatt aggaaaggaa cacaagtatg gggacgatat ttattcagtt ttcttttagt
    24241 tttttagcga ctgcggcatt tgccgttatt acaaatgtac ctaggcgttc attgatttgt
    24301 tgtggtcttt ctggtgcttt tggctggatg atctactgga tctgtgttca aataggcgga
    24361 tctgctgctt ttggttcatt gcttggttct ttaggagtag cattcatcag cgatcttttc
    24421 tctaaacgtt tgaaaatgcc cgtaacgatt ttcaatattc ccgggatggt tcctctagtc
    24481 cctggtggtt tagcttatca agcggttcga aatctcgtta ctgaatccta tcgagaagcg
    24541 gctcattatg cggtccaagc aattatgatt gctggagcaa tcgctttagg tcttgtatta
    24601 tcagaagtct ttaaccataa catccgtaat ttcaaagtaa agcgtgacgc aatcatgatg
    24661 aaacgaaaaa aacggctttt taaataaacg aagtgtaaca aagaaaaggt tgtgaaagag
    24721 acgttcagcc ttgagcgatg acaaaatatc tcacaaacat tgcgacaagt aaccgcagga
    24781 gcaataagaa gtaattatga gtattaaaaa aagttttgta aaaatagctt ctcacatttt
    24841 tacataaaat tgacttaata ctgagaaact gacttttgaa caccctctat ctgtaaaaaa
    24901 ggggctgcga catgattttt gtcacggccc ctcttcttta ttcaaatttt ttccaaaacg
    24961 ttcgttgata ataaacgatc catagagcgg aaagtattag aactaaaccg atcacaggaa
    25021 tattcactaa ccaaaatgga taaaacaaag ccaacattcc gtataagacg ataagaataa
    25081 tactgatgat caatgaaccc atcatagttg cgactaaacc caaacttcct gaacctctgt
    25141 taaataattg gttaatattg gtccagttca gcagcagcaa ccgataatct ctagcgaaat
    25201 aacgtagtga caataagtag cagccgaata aagaaccaaa tagcaagcta gggataaaaa
    25261 acaaaggcag ctgaaaagac agtccgctta ataatgcgat cccaccagtt aaaaaactct
    25321 gcaatatcca tccgaatctg aacttttctt ttaaatattg gttcatagag attggcaaag
    25381 aacggataaa cagaaaattt tcttgatcca aagaaataag attgctgata aaagaagtct
    25441 gattaactgt taagaaagcc aatgcgatcc ctaccaggaa aacaacaccg attaacttat
    25501 tatctaaatc agttaatttt atttcgcctc ctagggcaaa agcaagaata aaaatgattg
    25561 gagttaacaa ggaagaagaa agaacttgca taatcaaatt aggttctttt actaattgag
    25621 cattgtaact aaataaaagc tgatgcacat tttggttctt tttatgggtt ctttttattt
    25681 tgaactcact gtttgaatca gtcagttgct ctgtaagctt tggtactatc agctgtttta
    25741 cagcaaggaa aaatcccaga gccgtgatag ctagtattcc ccaacccaat aaaccttgtt
    25801 gagaaagtgg ctgactggca gcatcataga atggcaataa tatcgaaatc ggatgccgat
    25861 ctgttaactc attttcaata gtccccgttt gatgattcat ccacatgatt ccagcaaatg
    25921 cgatcagcat cgagctgcca agcaagatac tagaaactgt ttttctatgt tttttaaaca
    25981 ctgctgttcg agccaaacca aaaacaatca aactagccag acaaaaaaga ataatcaaaa
    26041 atagagaaaa caaaaggatt gagataatga tagtaagcaa aatccctaga tcagctcgcc
    26101 atccggttaa aataaacatg actagaagcg gaaaaacaaa aggaatgatg gtcaaagcaa
    26161 ctaccaaaat ctttgctgaa aaaacctgtt cttgtccaaa aggcagaggc aaaaatactt
    26221 gcaggtcatt tccttcaaaa aagatattat aaatgactga tatactttga gttaaaccta
    26281 acataccaaa aagtgccacg taataagtaa agaaacctgg caatttaaca aagttcatag
    26341 caaacatagc aaatccgtaa atcagtaaaa aaatcagccc tgaaaaaaga ttttgagaca
    26401 aaagatagat agttaatcgc tttccctttt ttcctttctc tcttgcttta ttcgtgagct
    26461 gtggattaac atataaaaga ttaactcgaa ttaattctaa taattgtcgc ttatacatac
    26521 ggtccatctc ctgtcgcttg ccttccagcc attttcaaat aaatcttttc tagcgtttca
    26581 tcaggtgagc cattcaataa ttcactaact gccccctgat aaatcaattc acctttcttc
    26641 aaaatagcca gtttatcgca taactgttgt gcggtatcca atacatgtgt agaaaaaatg
    26701 actgtttttc cttttgcggc atgagccttc atcatttctt tcaaatcaaa tgctgcttga
    26761 ggatcaagtc cttgcaaagg ttcatccaat acccaaatat ctggatctgg cagcaacgtg
    26821 ccgatcaaaa tcgttttttg acgcattcca tgtgaaaaac ttgcgattgt ttcattttga
    26881 tgactataca tatcaaaaag cgctgtcaat tctgctaaac gcttttcttt tttttgtgtg
    26941 tctaattcat aggcagctga aatcaagtcc caatattctc cagccgtcaa ttgtaaaaaa
    27001 atatctgggg aatcaggcac ataaccgatt ttttgtttga tactcaatcg attttccgtc
    27061 aatttcattc catctactaa aatcgttccc gatgatggtt caataatact aactaaactt
    27121 ttaatcgtag ttgattttcc ggcaccatta tgtcctaaaa atccaaaaat ttccccttgt
    27181 cttatcgaga gagacaagtc ttttaatgct tgttttttcc cgtaactttt acttacattg
    27241 atgaattcaa tcatttctgt actccttttg tttgttatta ctttttattg tacccttcgt
    27301 tattggtgga gtaaatgtca aaaagagtgc ataacaaaaa aggatagaaa cgactaggct
    27361 gctacttggg ttgttctctt ctacaggaaa acactcttct aacaggtaag atatgagtct
    27421 ttgttttctt taaaatgatt cattttctat cttttcttgc ataaaattct ttagtttatc
    27481 aatacttctc tttcccatct ctagttgttc tccatttgca aatgttacta tttcgtttac
    27541 tctgctaata gatgtaatgt tttcagtatt aatgatataa gcttttaaat ctttacataa
    27601 atactcatat tcgagtgatt ttttatattt tttaattgtg ccgtttacga gaatctcttc
    27661 atctttcaat actaggccta ttttattttt ataacctggc atgctcatta gataaaggat
    27721 ttcatcgtaa tggatatagt gatcgctatt accataacgg acagttgtcc accttttttt
    27781 cgtagcatgt tgaacaggat agttttcttt ttctttcaat aagtaacttt ggatgctttt
    27841 tttatttttt tcataagtga attcttttat caaataacca ctaggcgtaa tctttcgatt
    27901 aataacagtt attgctttat tcggatgaga cgttagataa acaattttac acttttcatt
    27961 cttttctcta agcatttcgc ctagttcgat accgctataa taggcgttca aatcgatgtc
    28021 taggaaaaaa atatctgagg aatagatttc attattttta atgaattcaa caaattgtat
    28081 aacgttcaat ccctgaacga tctcaaattt ccaaggactt aataaaattc tggattcttc
    28141 caaaatttct actagcattt tttcaaaaac caaactatca tccaaaataa atatacgcgt
    28201 taccataaaa agtacctcca ctcgatattt tactatcaaa atcatttcat acaacttttc
    28261 aacatacatg ttaggaataa attgtaattc tcttcacaat cttttccaac acctttgaaa
    28321 ccgatatcaa atactttcag gatgctgctt ctaaaataaa tatcaaacaa atgaatacat
    28381 catgcaaaaa aagccagaca accgacgtcc ttgcgtgtca gctgtctgag ctatgtttat
    28441 ttattttgtt cttttaaaaa gaacgataca catactgatt tttcggagca gagactttct
    28501 cagcgtttgt aacaactaca gatgggattt cacgcttgaa tggttgataa tagtctgatt
    28561 ggatggttcc ttctatttta taccattcat catttttaac cgttactcct tccggcatat
    28621 gcgtcaacaa accaaagact cctgaatctg ccacacaatg gataatgccg aatcggaaca
    28681 agaagatatc tgtattgcta tcgttcggtg tttggtaaac aaatccttca tagctgattt
    28741 ttttgccaat gaattcgcta gggtaattat aaattagctc cataacttct aaatagtttt
    28801 catctgtgat cttgatagtt tgcttatccc catacttttc tttcaactca ttcatttggt
    28861 ctaagtagtc tgatttgttg aaataaatac tggtatccgg ctttaagtat tgtgtctgca
    28921 tctccggatc ccctactgat tctttactta ctgggaaatt aaatcctttg gcttctacga
    28981 tcgtagtgtc gagactaact gttggaaaca acgtccccac gattactggc aaagctagca
    29041 gtacataagc gattccacgt tgataaggtt ttgacaaccc atggtcatga tcgtgctcgt
    29101 gtgccttttc ttctgctttt ccgtttttga cccacaaata cagctgaact aaagccaaaa
    29161 gagcagataa aatcattgaa agaatagcta agtagcgata atggacattg atatattgat
    29221 cgagtttgcc agaaacttgc aagtacatca tcaattcgaa atacccagat aaaatcaaaa
    29281 accgcagcat attttccctc ctaaataaat aatgtgaatc caataacgct aagggcaatc
    29341 agtccgatca gcgataaaat aaagcgtcct gtaaaatatc gtttcatcat cagtagattt
    29401 ttgatatcga ccattgggcc aaagaccaaa aaggcagcta caggtgctgt gccgaacaga
    29461 cttaacaaag aagatcctat aaacgcatct gcttctgagc aaagagacat cgtaaaggcc
    29521 aataacagca tgatgataat ggctaaaatc tttgttgagc cgagcgttag cataattcta
    29581 gttggtaaat aagtctgcat cgcagctgcg attaatccgc caatgatcaa ataacgacct
    29641 gtatcaaaaa attcgtcgat tgaatgtgtc aacacatgcc cagtttgatg gatcagctga
    29701 ttttttggtt cattcttctc actttgttct tcttcatgga catgatgatg gtgattttct
    29761 gctactttag acgtgatttt ttctttcaat acagcgtctt tttgaaaata ggcaagccag
    29821 acaccaatca caagggcaac aaaaaagctg cctatcaccc gccagcttgc catctgccaa
    29881 gaattgccaa atgcgataaa agtggaaaaa atcacgattg gattgatgat cggagcagtc
    29941 agcataaaag caaacgctgt gtgaactggt acgccttttt taacaaattg atgaacgatc
    30001 ggtacgatgc cgcattcaca tgaaggaaag aaaaatccta agatcgaacc agtaaaaata
    30061 gagaagatac gattttcagg aagccatctc ttcacacgtt ctggggtcaa aaatacttgt
    30121 aaggcgcctg agataagaca gcctaataat acgaaaggta atgcttcaat aacgatcgat
    30181 aagaaaatcg tactcatctg caaaaccgaa tttggaataa aagaaaacat gagtttcctc
    30241 ctttttattt ctagttcatt cgctttgcaa atatacgctt ttattcaaaa aaaacaagtt
    30301 gctctgtaaa tttttacaca actcttattt tttaccaaag cacttcaatt gactttttct
    30361 gttattccca ttaaattaag gtctcataca tatcacttct atcataaaag ggagaataaa
    30421 aatgaaacaa accactaact tgactgaagt tcaagacata ctgcaacagt catccgttgc
    30481 cgtcatttat ctttcgatgc ctaattgcag tgtttgtcac gctgttcgtc cacgactaga
    30541 ggaacttctc acacattatg atattccggc acttcatttg gatgcatttg aaacaccaga
    30601 agtagctagt aaatttgaag tgctgactgc gccagttgtc ctgatttttc atcaaggaaa
    30661 agaagtcttt cggcaagcac ggttcatcga ctttaaaaaa atccgttatc tactagatga
    30721 actgacagca gaagatgatt ccctttctta tgaagaaatc ttccgaacaa aataatcgtt
    30781 gtccaaacag aaaaaagcga ttgaacaagt gaaagttttg ccttcatttg ttcaatcgct
    30841 ttttattttt attctgctgt attttcggaa tgcgcatttg cgtcagaatg caagaaatag
    30901 atcaaggttt gcaattcatt cgtcaaatca acattttgga tcaatacatc tgacggagca
    30961 ttcaatcgag cagcggtaaa gttcaagatt cctttgattc ctgcttccgt taactgattg
    31021 actacttctt gtgctctttc agcgggtatc gttaaaattg ctacttcgat ttgttggatc
    31081 ttgatttgtt ctgacatatc ttccattgga taaacgggga taccgtctac gatgcgccca
    31141 acgatttcct cattcacatc aaaagcacaa ctgatacgta tgctattact ttgatggaat
    31201 ttgtatttta gtaaagcact tcccaagttc cctacaccga tcagcgcaac atttgtcaat
    31261 tgatcgtcgt ttaatgtctt tgcaaaaaag tgcataagat cttctacatc ataaccatac
    31321 ccacgttttc ctaattcgcc aaaataagaa aaatctcgac ggatcgttgc actatctact
    31381 tgaacggctt cacttaattc agttgaagac acttttttct ttccagcatt atttaaaatc
    31441 cttaaatagc gataatacaa aggcagtctt ttagctgtcg cctttggaat aatatgatct
    31501 ttcacgaaat gacctccacg tattgtctaa ttacatcttt gatttctcca tcatagcagt
    31561 atttatagga aaaaatcaat tccattgctc agatattgtg aaattttatt ctttattcat
    31621 ttatttatca tttctgcaaa tctcgcagta taatggaatt tatggtagac tactaattga
    31681 aaaatagttt tttatttgag gagaattcac aaagtagaaa agaggattcc atgatattat
    31741 tacaagccaa tcagattgct cgccattttg gtgcagaagt cttatttgaa aacatacatt
    31801 tagaaatcag tacaggcgct cgtgtcgctt tagttggcag aaatggcgct ggaaaatcga
    31861 ctttattaaa gatcattgct ggaattgaag cacctgatga aggaaagatc gctaaaaata
    31921 aaacagcgac tctcggatac ctcgctcagg acacaggact tgattccaat gaaacagttt
    31981 ggaacgagat gctgaaagct tttgaacaag ttagacaaat ggaagagcgg atgcgcgagc
    32041 tagagatttt cattagcgaa ggtacgccag acacacctgc ttatagttct tatttaaaag
    32101 aatacgaccg gctgcaacac gatttttcag atcgaaacgg ctatggttat gaaaatgaaa
    32161 ttcgttccgt attgcatggg tttaaattcg attcttcatt ttatgatcag aaaatcgata
    32221 ctttatcagg cggacagcgc acacgtttag ctttagctcg catgcttttg caacaccctg
    32281 acattttgat tctagatgaa ccaacgaacc atttagatat cgagacactt tcctggcttg
    32341 agaattatct gcaaagctat actggtgcat tattgattgt ttcccatgac cgttattttt
    32401 tagataaagt agtcaatgaa gtctatgaat taagcagaag aaaaatgcgc cattacaaag
    32461 gtaactattc gaaatatcta gatttgaaag cagaacagtt agcaagtgaa tggaaggctt
    32521 atgaaaagca gcaaacagaa atccataaat tagaagactt cgttgctcgg aaccttgttc
    32581 gcgcctctac cacaaaacga gcgcaaagcc gcagaaagac attagaaaaa atggaccggc
    32641 tggatcgtcc tcaaggggat gaaaaacaag caaactttct attcagtata gaaaagcctt
    32701 ctggaaatgt agtcttgcaa atcgaagatg ccgctatcgg atatgataat gtcaccttat
    32761 ctgaaccaat caatctagat atccgtcgtc aagaagcgat tgctctagta ggtccgaatg
    32821 gtatcgggaa atcgacgttg ctgaaatcaa tcattcacca gatccctttt atccgtggaa
    32881 aagaaacgct agggacaaat gtcaccatcg gctattacga tcaaggtcaa gctgatctgc
    32941 atacaaacaa gacgatccta gcagaattgt gggatgagca tcctaccact ccagaaaaag
    33001 agatccgaag tgctttaggt gctttcttat tttctggcga agatgtagaa aaaccaatcc
    33061 ctctgctaag tggcggtgaa aaagcacggg ttgctttagc caagttagcg atgaacaaag
    33121 aaaatttttt gattttggat gaaccaacaa accatttaga tattgacaac aaagaagtat
    33181 tagaaaatgc attgatcgat tatgacggca cactgctttt tgtttcccat gaccgatatt
    33241 tcatcaatcg gatcgcgaca aaagtcgtcg aactctctga aaatggcagc aaagtctatc
    33301 taggagacta tgattattat ttagagaaaa agcaggaaga agaagaaatc gccgaattgt
    33361 tggcacaaga tgagccagaa tctgctcctg ctcccacgaa caaatctgat tattaccaaa
    33421 gcaaagaaca gcaaaagctt atccgtagcc ttcaacgaaa aattactcag gttgaagaag
    33481 aaatggcgcg gatcgatgaa tggatcgatc agttggaaca agaaatggtc gcgccagaaa
    33541 acctggaaga tcacgtaaaa ctcaatgagc tgaaccaaga tttagaagct gctagacaag
    33601 atcaagaaac aaaattgacg gaatgggaag aactaagctt ggaattagaa gaatatgaaa
    33661 attaacgaaa aaaccaaaac agaaaccatt catgctgttt tggtttttct ttttttattt
    33721 tatcaaacaa aaattccata tttacctttt tcaccaataa gaagaccaat tactagtcat
    33781 tctcactaaa gcttctaaat aatagtaatc accccaaata caaggtgtat ttaccccatt
    33841 atttttgggc ttattataaa cagactgtgt taaaaagcca tcttcttctt ccgttgtagc
    33901 atatctttct ttcaattgtc gcataatttt ccaaacagca gactggtata agttcttttc
    33961 tgttttgtct aatagacctg attctattaa ttctaataat ccacaaacca tgatcaccat
    34021 actagatgta tctttttctt ctctgctaga atcatcaaag atcaaatccc aataacaaat
    34081 ggtatcttct ggcaaccgat tcataaaata attggctaat attttgctta aatcaaaata
    34141 tttttgttct ttcaaataac gataacttaa tgcaaaaccg taaatccccc atgcttggcc
    34201 tctagcccaa caggaattat cactataacc ttgatgcgta cttccatatc ttggttttcc
    34261 atctttgaca tccatataaa atgtatgata agttgaacca tcttctctta ctaaataatc
    34321 tgctgcattt tgaatatgag cctgagcagc ttttttatat ttttgatttc cagtttcttc
    34381 actcgcccaa tacaataatg gaagattcat gcaacaatcc atgatcattc taccttgttg
    34441 tgaaggatca ctaggatctc cccaagcttg tataactcct gccttctccc aaaaacgctg
    34501 aagtaatgtt tctgcagcat caattgaagc ttccttcatt tttcgatttc ccgttatttt
    34561 ataatctgct acggttgata aagaatacaa aaaaccaaga tcgtgatgat tagtgataat
    34621 ttgacagtca atcctgtgga taaaatctat atctgctttt tcagctgttt gttgaaataa
    34681 aggatcaccc gtcttctcaa ataacaacca attaattcct gtccaaaatc cttctgtcca
    34741 accaatattg tctcttaatg gataacgtcc ttttatagga cactcgcttg ggaattgata
    34801 ctgactgtta ctgatacgtt tgattaacct ctccgtgtgt ctgcgacaac gctcgatctc
    34861 attattccat tctttttcca ttaattcttt ataacattca tttatccatt tttctggatg
    34921 tattatctct tcaaacatca ctttatcaag catttcccca ccagccttta gcataatttt
    34981 agtctttttt tattgttttt attttggata gttagcccgg ttgtcccatc aaaatcaatt
    35041 ttgggacgat tgttccatac ttctaaacta taatcccgat cttgatgagc aaccactcct
    35101 gttccgagcc aatgggttcc ttttccaaat gtaccctcta atccaggaat aaaagtgttt
    35161 tcccatgtca tcaagtttgt attgggcaaa cccataatag ctgtggattt tcgtttaata
    35221 gtatcgtcac ttaaacagat aatacctgaa aagccagctt cactcaccct atagttttcc
    35281 ttgtcttctt ctatgattat tccttctttc tcaggagaac attcaatagc aaaccctgtc
    35341 tcatatagaa catattctgt atctaattct actttgtgta cgcgaatctg ccagccttca
    35401 aaaggaataa gccaagttct gatttttgcc tgtaaagtag gttcccatgt agaggcaagt
    35461 acctctttct tacatacaat gtctcgtaca ttatttcgaa cgatgaactg tccataggtt
    35521 ttgatgctct cattcttaaa actggtcgtg atatatgtgt ccgctcgctg aatccctagc
    35581 attgaatcca ttgccatttc tgctttcaat tgattcgctc gcggtatcga aaaaccaaat
    35641 tgactagaat aagcaaattt taaatatttt tcattggtca atgtatggaa atttggccct
    35701 aattgtcccg cattcaaaaa aaatgtatgt ccattatcat gttgtatgag caaattggct
    35761 tctgaaagaa gtttagttcc ttcacgaata ggcataggca tttctttagc cgtccaatac
    35821 tcatggtctt caggtagcgc caacaataaa aaaatcttat tcagccataa tggagataac
    35881 gtactattat agggttcagt caatgtcaat tgagggtagg tataaccaat attcaggata
    35941 cctttttcat caaatatttc tttttgcatc caccatctta tattccgatt gactaacccc
    36001 ttgatttcac ctaatttaaa aggcaaaaga tcggcccaca acatagctga ccaaaagctt
    36061 gaaactgcaa aacgataaat catgcttcga ccaaaaggca catttgcacc atcttccgca
    36121 aaaaaatgaa tatagtctct agaaaaatca atagctcggt tcttatatat ctggctaatg
    36181 ggcttttctg gttctagtac gctataaatc aaaccataat aatgaaatgc aaaaggatta
    36241 taataatctt ggcgacctct tgaactgtct cgataccagc cattttgaag ataacaattt
    36301 tctatattat caaatgcttc tttcagtgct gattctttaa ctggataacc aaatttttgg
    36361 ataattgttc cgacaattat cttaaaaaat tgccaattac catctgcaca ttcatattca
    36421 aaaatttgcg agaaccaatg aataatctgg cttttttctc ctgtatctaa ttttttccat
    36481 aataattgtt catgatgata taacgctaat aacattgcgg gcatttctac catacgctgg
    36541 tctctttcat gtatttctcc ccaataatcg ggatgggaag gatctgttcc agcttttatt
    36601 cctgatagaa ttaatttcaa ccatcgttca tctaattggt caattgcggg ccccgctccc
    36661 cataaaaccc gagagaatcc ttccattcct gcaattttat ttccatatcc taccccttga
    36721 tgtatataat caatttgtgc gccacttgct cgataaaacg gctggagtgg ttgatttatc
    36781 tttttaaata agtcaaagta atcctgtctg gtccttaata gtggtactgg atgtttcatt
    36841 gtattttctc ctctttttac taccaaatag ctaattccga ctgttctaat cgaagtaagc
    36901 cttcaataaa aaaataatca gaatagatca gtggcacatt ataagtcagt tctctatggt
    36961 atgcttctgc tccgcctcca atgatcccat cttcatccat attccaattt gcatagtgct
    37021 tttctgtctt ttggagtata ttgatagcag cttcatgata catttttgat cgtacagagg
    37081 aaacatatcc tgctaattcc agaagaccgc atgcagcgca tactccagca ctggtatcaa
    37141 tattcgaatc ttttacagca aaatcaatga gaggaatata accagttttt tcgattttct
    37201 gaataaaatt tactgctatc ttttctgcta tagctagata gtacggattt tttgtgtaac
    37261 gataacttaa cgcgaatcca tataaagccc atgcatttcc tctgctccaa caagaattct
    37321 cattgtatcc ttgcccgcca agtaaccgaa tatatttccc tgattctgca tcaaattctg
    37381 cgatatgccc ggttgatcca tctttcctca ctagatactt agctgttgta tctgcatgct
    37441 gccgagcaat tttagagaac ctcggatcac cagtttccct cgaagcccaa tacagtaatg
    37501 gtaaattcat catactatca ataatcatcc aaccaggttt atggtcattc catgctacta
    37561 aatagttccc tgaaatatta tagcgtccag caagtaccgt agctgcatgt aaccctagtt
    37621 gtcgactatg tttgttttga gactgttgat aatgtgcaat agccgatggt aagaataaaa
    37681 aacctacatc atgatgaacg tctgaaaaat ggtacagggc agattctaat aattgttctt
    37741 gttgtattgc tgcctctttg aacttttctc gttttgtctt gtgaaagagc tgccataaaa
    37801 taccactcca aaaaccattg gtccaccagt cgattcctct gtcctttatt acgtctgtat
    37861 attttccgtt gtaagaaata tatggaattt tattccccat tctgtctaat tccgcatcta
    37921 tcttttcaga agctacattc aaaatttttc ttgaccattc cttcgtctgt tcattcatgg
    37981 atatcccgcc attcttttaa tttttatgaa tgtggagttg ctcctagaac gaactagatg
    38041 gttaacattc gttatttttt ttacttattt gcagctccaa tgtcattctc cttaaattta
    38101 gactgcgccc acacataaat caagaccatt gggatcactg aagttgctaa aattagcata
    38161 attgcgccat aattaattgg ctcacctgta ctagaaaccg tcatattttt gataattaag
    38221 ggaaccgtat atttatcttt atctgaaagc atgactaatg gaaatagata ttgattccaa
    38281 cttcccataa agataagtaa accactagta ataatcgtag gtgataaaat cggtacagcg
    38341 attttcgtaa aaatcaccca ctcattggca ccatcgattc tggcagcctc catcagtgct
    38401 gtaggaaatt gactgctata ttgtcgcatc ataaacactg aagttgtact ggcaatcgaa
    38461 gggatgatca cacctgcata agtattcgat aatcctaaac gactcataat gtaaaataaa
    38521 ggaatcaatg tggtaaaaaa aggcaccatc ctagatagca taactgtatt gaacaacagt
    38581 ttattcccca taaaacgata ctttgctaat gcataacccg ccattgtaga actggctgta
    38641 gctaaaactg tactgattac agcaataaca atcgaattcc aaataatcaa gggataatta
    38701 tatctcgcca tgatggcttg ccagtttttt aatagcatat ccccaaactt gaaattgatt
    38761 ccgccactta aaatttcttg attactttgc gttgaagcta caatcatata taaatatggc
    38821 atcaaaaata ttaaggcacc aaacacaata atgacgtacg taaaaattct gctttgtatc
    38881 ttttgtttag tcatttttat cacctccgaa tttaaattga atagccgata atataacaga
    38941 tacaaacacc atcgtccagg caatagcaga ggcttttcca aaatcaacca tttcaaaact
    39001 tgttttatat aaattgactc ctacgaccaa agctgaattt tctggtccat tggaagtccc
    39061 aaagaatata tttgggatat tgaaattacc caagccattg atagtggcta aaactgtggc
    39121 cattaaaatg attggcttta gcatggggat cgttaataaa aagaattgcc gaaatttcga
    39181 tgctccatct atttcagcac tttcgtatat ctctttagaa atcccttgaa gaccagctaa
    39241 aaataaaata gtgttatatc ctacactaag ccaaatcatc gtgatgatca ttgatattcg
    39301 tatccaaaaa ggatttgtta accactgtac accgttaatt cctagcgcat tcaaaaatcc
    39361 attgaataac ccagtcggat tgaaaaaagt catgaatacg gaagctacag ccaccgttga
    39421 tgtaatggtt ggaatataat agacagttct aaaaaatcct tttcctttta actgtgctga
    39481 attcaataaa acagcaaagt aaatagctaa tagcatcgtt attggaattg atcctgccat
    39541 gataatcaaa acattcgtgt aagatttaat aaacaatgga tctcggaaga tagctagata
    39601 attgtcaaat ccaacaaatt caaatgagta gccaattttc ataaaactaa aagcaaacga
    39661 gataatgatg ggaatcaaaa tcgtcacaat aaagaaaata acaaaaggtg tgaccaatcc
    39721 ataagcactt tttttatgag acgtatctgt tgcttttttc ttgctgttct ttattgtctt
    39781 gcttggtaac gaagattgca tcatcgttaa gtcctcctaa tattttttaa tcaccagtta
    39841 attttacgcc gtacttatga gcaaaatttt ctgcttcttt tagatatgaa ttttcaaaat
    39901 cacctgtttg ccaatagtta tatgcagcgg tagtcaaata agacgtagca tctgaataag
    39961 tggctggtaa aacagtattt gatgtatttt cattgatttt attcaatagt tcatagtatt
    40021 tttgtcctcc ttagtagtca aactttttct cagctgcttc tgtttgatag gccaatgagt
    40081 tagatgtagc cacgcccagc tccagtgcgt tggctaagca ttcttcatct gtcagcataa
    40141 atgtaagaaa ttgttgtgcc acttgtggat ttttggcatc tttagggaca taaaaacttg
    40201 atcctcctga tactgcacct tttcctggat tttcttttga aaaaggaatc agtggagcca
    40261 tgcgccattt gtcagatgca tcaggaaaat tcaaagacat attcgtagca taccagccgc
    40321 cagcaacaaa cattgcagat tcttgaaatg ctttctcagc atcttgtgca ccgtagaaat
    40381 gtacaatatc tgagtcgatc atttctttga ttaactttgc agcatgtttc gcttctttag
    40441 tattcagacg gatatttcct tcttcatcaa gcaaagattg attctgctgg gctagcatgt
    40501 tgataaacaa ttcttggtcc ccagattctg gcaaggcaat tccaaaacta ccagtttttt
    40561 cttttaatgc ttttgccacc tggatatatt cttcccaaga actgatttct tcaaaatcta
    40621 cacctatttc agcaaatttt tttggttgat aataacaaag tgctggggta aaatcactag
    40681 cccaaggaat aatcgtttca ttactcgttt gttgacgcaa aatattcaat ttttgatcat
    40741 aaaactgatc gccatatttg tcataaaatc catattcatc agcactataa aaagcatctt
    40801 gaaatttttc cagcacacct gctgctgaag tgtctgccat ggagataata tccggcatat
    40861 cttcgtgtgt taccaatttt ggggtgatca tttgtactgt tgctgttccc gaagctacat
    40921 tcacaatttt taagtcaata tttgctccag ttttgcggtt atagattttt gcagcatttt
    40981 caacatagtt tgtcagtttg ccgtttgcga catatacttc taatgtagtg gcttttttta
    41041 tcattggatc tgcgatgttt gctgttactt cttcgttagt ttttccacat gcacttaagc
    41101 tgaataatag ggtaatgttt agcaaagcta tcaccaattt gtatcttttt ttcatgtcta
    41161 tcccttcttt cttttcaagt tcttatataa aacgctttca cttatgtata ttaacggaat
    41221 tagtaacaca aatatttata taaaaaaata ttttacttgt cgttttggct tttcattttt
    41281 gttataatag tcattaatta taaatagaaa gctttttata taaaaagaga aaggaaagtg
    41341 gttcttttgt taacaaacaa ccaatcctcc aatcttgtca aaaaaacact aacctattcc
    41401 atagataccc atcttcattt atctgctgct ccctattttc gactactaat aaatgaaagc
    41461 gctaatttat atgctgaatt tgcacataaa tctatagaac tagataatcc ttccctttta
    41521 ttcattgata aacagcaaga agtccaaatc ttttctactc aaaaggaaac acaaactttt
    41581 atcattatcc agttttattt tgatgagcaa ttattagcac atattacggg acaatctttt
    41641 tctatagatc aagaaataac atctatcatt acttttctga aaaatgaaca gttcaaaatt
    41701 gattatctaa aacatagtaa gccagctatt tcctatgatc aggaaatcaa ttcttttttc
    41761 atactatgcc aacagatgag cattcatttg ctttccttat tagttactta ttgtctgcaa
    41821 aaaattcaat tgtcttcctt accaaggcat tatcaacagg aacttgcttt attgacaata
    41881 ccttcaaatg agaaagtcat tcctaaaaaa aagcatattc tttattcaga tgaattagtt
    41941 gatccaatca tacgatattt agaagaacat ctttcagaaa attttttgct tgaacaatta
    42001 gcccaaattt tttttatcag tccagccagc ttaaaaaaac attttagaaa agtgaatgga
    42061 aaaagtgtta ttagctattt taaagaacta aaaatggaaa aagcaaaacg tctcgtgcta
    42121 gaaaatgaat taacctatac agaaattgca gatatattag gatttcattc gatccatcat
    42181 ttttcttcag cttttaaaaa atatacaggg ttatcccctt caaagtatta tctatcctta
    42241 aaatagaaaa aaatttttag gttttatcca caaattattt ctctatattt tctgtctatt
    42301 caaaataaac aataattttc cggcacaatt atttgctgtt ttttaccata acatagtacg
    42361 atcaacgtag aaaaggagat gtttttatga aagttgttgt cattggcggt gtagctggcg
    42421 gtccttcatt tgccactcgt ttccgtcgat tgaatgaagc gcacgaaatc attatctatg
    42481 aacgcggaga aaatatttct tatgcaagtt gtgctttgcc ttattattta ggaggtgtga
    42541 tcactgaccg tgactcgctg atcgaacgta caccagaaat attgaaaaca aaaaacaaca
    42601 tcgatgtctt tactaaacac gaagtaacag caatcgatcc ttctactaag cgattaacag
    42661 ttaaagacct atccacaaat gaagaaataa aaacagatta cgataagttg atcatctctt
    42721 ctggtgctag accagattat ccggatattc ccggagtttt tgaagcagaa aacggctttg
    42781 tcctccgtag tgtgacggat gcggatcgaa tcaaatcgtt ccttgaagaa aaaaatccac
    42841 aacatgtcgt cattcttggt gcaggtgtta tgggtctgga attagctgag aatttcaagc
    42901 atcgcggctt agacgtgact ttaatcgatc aattgccaca agtcgctttc ccttatgatc
    42961 cagaaattgc taatttagtt tatgacaaat tgctgaaaga aggattagcc gttcatttag
    43021 aaacaagagt tactgagatc cgtgataaag gtcgagaaat agtattatca gatggctccg
    43081 tcctttctgc tgatatgcta atttttgctg ttggtgtttc tccgaagaat gaagtggtga
    43141 aagcaaccgg catacaatta tcagatacag gtcagatcat tgttgatgac cagttacaaa
    43201 ccaatctgcc ggacatctat gcgattggcg atattatcga aacgactagt gtagtgactg
    43261 gtcagccgat ccaaagtatg ctttccagtg cggccaatcg tcaaggacat atgctggcag
    43321 atattttaaa tggtacgcct atgcgctatc gcggatatat tggtgcaggt gtcgcaaaaa
    43381 tctttgatca tacagcaagt tatgcgggaa tgacagaaca tgaattaaaa gcatcaggca
    43441 taacaaatta taaaactgtt tttatcactc cctttgacca tgcctatttc tatccagaag
    43501 ctacaagatt aaatctaaag ctgatttttg atgcagatag cggtcgtatt ttaggtggac
    43561 aagcatttgg agaaaaaggt gtcgataaac ggatgggaga actttctgta gcaatcaccg
    43621 gaaacttgac agtctttgat ttgcctgatt tggagttgcc ttactctcca ccgtattcta
    43681 ctacccgtga cccgttgaat atagctggtt atgtcgcaat caatcaaatg acgaatatcg
    43741 tagaaacgat caaagcaagt gatatacccg aaaacgattt gaaagaagcg ttctttttag
    43801 atatacgtga acctaataaa gcaccttctg gcagtatctc ggcaacaaaa aatattccaa
    43861 tgaatgagtt acgagatcga atcaatgaaa tcccaaaaga taaaaaagtt tacattactt
    43921 tcagaagagg attgaatact tatacttctg cccgaatctt ggcaggtttg ggtatcaaag
    43981 cgattttgat tgaagaataa aaaaacgacc gcggtgggta gccgcggtct aggagttatt
    44041 tttacttgag gagtaaaaat gaaaaagtat atagggttgt tggttggtat gtatatagaa
    44101 tagaagataa atgtgaagaa attgtgcatt atttcttcac atttattagg ttatagttta
    44161 agaaagttta aacattgcgc aatttaatta ttttagctgt ttcttttcat aaaaaaacat
    44221 gttgtgactc tgagacaaat catagtccat agtgatgtct ctagagtaac tacgcctaat
    44281 attacgaggc atcatattaa tctatcagca ctagtaccta aactagcatc cctttcgaat
    44341 attttttctt atataataaa gtttgctttc actcctctaa tctcaccaaa tcgactggct
    44401 tgcgttgtgt gatactagga actgattggt ttagaacgac ttttctattg taatcatatt
    44461 tttcgccatc ctcgttgtct tctaatcctt caatgaatga tccctaatgt gtgtattaaa
    44521 taatttaatt tttttgttcc tatttattta a
//
LOCUS       DAFBSV010000010        41870 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.010, whole genome shotgun sequence.
ACCESSION   DAFBSV010000010 DAFBSV010000000
VERSION     DAFBSV010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41870
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.010"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            113..559
                     /locus_tag="LLB18_000596"
     CDS             113..559
                     /locus_tag="LLB18_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5243622.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(618..1079)
                     /gene="mscL"
                     /locus_tag="LLB18_000597"
     CDS             complement(618..1079)
                     /gene="mscL"
                     /locus_tag="LLB18_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HBK5243623.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            1331..2599
                     /locus_tag="LLB18_000598"
     CDS             1331..2599
                     /locus_tag="LLB18_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBK5243624.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            2592..3878
                     /locus_tag="LLB18_000599"
     CDS             2592..3878
                     /locus_tag="LLB18_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBK5243625.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            4617..5540
                     /locus_tag="LLB18_000600"
     CDS             4617..5540
                     /locus_tag="LLB18_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5243626.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            5749..6327
                     /gene="pgsA"
                     /locus_tag="LLB18_000601"
     CDS             5749..6327
                     /gene="pgsA"
                     /locus_tag="LLB18_000601"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBK5243627.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            6567..7808
                     /locus_tag="LLB18_000602"
     CDS             6567..7808
                     /locus_tag="LLB18_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBK5243628.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            7917..8966
                     /gene="recA"
                     /locus_tag="LLB18_000603"
     CDS             7917..8966
                     /gene="recA"
                     /locus_tag="LLB18_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBK5243629.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            9377..10933
                     /gene="rny"
                     /locus_tag="LLB18_000604"
     CDS             9377..10933
                     /gene="rny"
                     /locus_tag="LLB18_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBK5243630.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(11012..11818)
                     /gene="proC"
                     /locus_tag="LLB18_000605"
     CDS             complement(11012..11818)
                     /gene="proC"
                     /locus_tag="LLB18_000605"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBK5243631.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            11959..14532
                     /gene="mprF"
                     /locus_tag="LLB18_000606"
     CDS             11959..14532
                     /gene="mprF"
                     /locus_tag="LLB18_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBK5243632.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            14674..15537
                     /locus_tag="LLB18_000607"
     CDS             14674..15537
                     /locus_tag="LLB18_000607"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBK5243633.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            15782..16720
                     /locus_tag="LLB18_000608"
     CDS             15782..16720
                     /locus_tag="LLB18_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBK5243634.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            16743..17423
                     /locus_tag="LLB18_000609"
     CDS             16743..17423
                     /locus_tag="LLB18_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBK5243635.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            17396..18220
                     /locus_tag="LLB18_000610"
     CDS             17396..18220
                     /locus_tag="LLB18_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBK5243636.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            18387..19205
                     /gene="purR"
                     /locus_tag="LLB18_000611"
     CDS             18387..19205
                     /gene="purR"
                     /locus_tag="LLB18_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBK5243637.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            19708..21081
                     /gene="glmU"
                     /locus_tag="LLB18_000612"
     CDS             19708..21081
                     /gene="glmU"
                     /locus_tag="LLB18_000612"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBK5243638.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            21175..22146
                     /locus_tag="LLB18_000613"
     CDS             21175..22146
                     /locus_tag="LLB18_000613"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBK5243639.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     regulatory      22152..22254
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            22320..22889
                     /gene="thiT"
                     /locus_tag="LLB18_000614"
     CDS             22320..22889
                     /gene="thiT"
                     /locus_tag="LLB18_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HBK5243640.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNSWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     gene            complement(22970..23743)
                     /locus_tag="LLB18_000615"
     CDS             complement(22970..23743)
                     /locus_tag="LLB18_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243641.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            24009..25709
                     /locus_tag="LLB18_000616"
     CDS             24009..25709
                     /locus_tag="LLB18_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBK5243642.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            25679..25897
                     /locus_tag="LLB18_000617"
     CDS             25679..25897
                     /locus_tag="LLB18_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HBK5243643.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            25917..26807
                     /locus_tag="LLB18_000618"
     CDS             25917..26807
                     /locus_tag="LLB18_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBK5243644.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            26825..27109
                     /locus_tag="LLB18_000619"
     CDS             26825..27109
                     /locus_tag="LLB18_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243645.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            27596..28210
                     /gene="gmk"
                     /locus_tag="LLB18_000620"
     CDS             27596..28210
                     /gene="gmk"
                     /locus_tag="LLB18_000620"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBK5243646.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            28215..28520
                     /locus_tag="LLB18_000621"
     CDS             28215..28520
                     /locus_tag="LLB18_000621"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBK5243647.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            28773..31181
                     /gene="priA"
                     /locus_tag="LLB18_000622"
     CDS             28773..31181
                     /gene="priA"
                     /locus_tag="LLB18_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBK5243648.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            31196..31687
                     /gene="def"
                     /locus_tag="LLB18_000623"
     CDS             31196..31687
                     /gene="def"
                     /locus_tag="LLB18_000623"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBK5243649.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            31680..32618
                     /locus_tag="LLB18_000624"
     CDS             31680..32618
                     /locus_tag="LLB18_000624"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBK5243650.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            32618..33976
                     /gene="rsmB"
                     /locus_tag="LLB18_000625"
     CDS             32618..33976
                     /gene="rsmB"
                     /locus_tag="LLB18_000625"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBK5243651.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            33989..34729
                     /locus_tag="LLB18_000626"
     CDS             33989..34729
                     /locus_tag="LLB18_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBK5243652.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            34726..36795
                     /gene="pknB"
                     /locus_tag="LLB18_000627"
     CDS             34726..36795
                     /gene="pknB"
                     /locus_tag="LLB18_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBK5243653.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            36960..37859
                     /gene="rsgA"
                     /locus_tag="LLB18_000628"
     CDS             36960..37859
                     /gene="rsgA"
                     /locus_tag="LLB18_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBK5243654.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            37872..38522
                     /locus_tag="LLB18_000629"
     CDS             37872..38522
                     /locus_tag="LLB18_000629"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBK5243655.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            38523..39161
                     /locus_tag="LLB18_000630"
     CDS             38523..39161
                     /locus_tag="LLB18_000630"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBK5243656.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            39316..40170
                     /gene="mreC"
                     /locus_tag="LLB18_000631"
     CDS             39316..40170
                     /gene="mreC"
                     /locus_tag="LLB18_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBK5243657.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            40174..40683
                     /gene="mreD"
                     /locus_tag="LLB18_000632"
     CDS             40174..40683
                     /gene="mreD"
                     /locus_tag="LLB18_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBK5243658.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            40938..>41870
                     /locus_tag="LLB18_000633"
     CDS             40938..>41870
                     /locus_tag="LLB18_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243659.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEE"
BASE COUNT        13816 a         7433 c         9054 g        11567 t
ORIGIN      
        1 ttttaactga agcagtttaa aaagcaaacg agcctgagat tcgtaaggtt cgtttgcttt
       61 tttgtgtgcg aatcggtatg ctaagaataa aaaagcaggg ggcgtttgct tagtggaata
      121 tcaggtaaag aaatttgaag aattgtcaac agcagagttt tacgcgatcg tcaaagaacg
      181 aatcgcagtt tttgttgtgg aacaacagtg tccttatcaa gaagttgatg acattgatgg
      241 acaagcttgg catacgtttt ttcaagatac tgatgggaag atccttgcct acacgcgagt
      301 atatgaagaa gcggagagta tccattttgg acgtgtcctt gttcatcagg acaaccgtaa
      361 agatggttta ggaagaaaga ttgttcaaga aacgattaac atgatccaga aaaattttcc
      421 agaaaaacca atcgtgatcg gcgcacaaga atacctacaa gctttttatg agtcgtttgg
      481 attcaaggca atctcagatg tgtatttgga agatgatatt ccacatatcg acatgaaaaa
      541 ggaacaagta gcaagttaag aatctaaaaa aagaaagccg acactgaaaa tcggctttct
      601 tttttttaga ttctttatta tttagaagta tcggaaagat ttgtttgctc tactggatgt
      661 gtattgtctt ctgccacttg tttggcaaga agatcgcgta tgtcactaag ataatcttct
      721 gcagtaggag tttcttccac ttccacttgc tcttctttgg agcgtaaatt cttcgcacgg
      781 tttgccgctt tgacaactaa gaataagaca aaaccagtga tcagaaatgt aatgatagca
      841 ctaataacgt taccaaacgc aaatgtgacg ccttttgtcg gcgaccagtc aagaattgaa
      901 agtgctcctt ctaaatcaga agtacctgtg atcattgcga caaaccaacc tattagtggt
      961 gtgatcaagc cttgcaccac ttggtttacg atgcttgtaa acgcactacc aataacaacg
     1021 ccgacagcaa gatccaagac atctccacgc atgatgaact ctttgaattc tttgatcatg
     1081 aatgaccctc ccttctttta tttgtcttta gtatatcgaa aaataaaaaa taaaaaaaca
     1141 atatacgctt ttagccgtct gtttcttttg ataaaaaaca tctatgctat actataaagt
     1201 gtaacatcat ttagaaaaaa cggcgaattg cctgaactta taaatttcaa gcagaggaat
     1261 aagtaaaaaa ggcaggttga cccattaaaa gagtaagcgg gcaatcaact gtgaaaagga
     1321 gcatataaat atggtgtatc aattggcaga aggcgtgaat cttcatgtct taccaacaaa
     1381 acaatacaaa acgatccgga tttttatccg ttttactgcg cgtctgcaac aagaagtcat
     1441 cacgaaacgt tcacttctca gcagcatgtt ggaaacaaat agtttgaatt atccggatca
     1501 gacaaagtta agtgcgcaac ttgcagagct ttatggcgca agctttggat tatcagttag
     1561 aaaaaaagga aatttacatt ggctaaacgc agggatcagt tttgtgaatg gtgaatatgt
     1621 caatgatcca aacctttttt ctcaagcggt agatttttta aaagaggttt tattttatcc
     1681 aaatattaaa aatcatcagt ttgatcagtt gacgtttgac ttggaaaaga acaatctgcg
     1741 tctatatttg gaaagtttga aggaagataa acaaactttt gcttcctatg ccttgcaaga
     1801 actttatttt gaaaacagcc cggaacaaaa gatcccaggg ttgggcgtag tcgaagattt
     1861 ggacaagatc actgctagtt cgctagcgtc ctactatcaa gaaatgatgg caaatgatca
     1921 aatcgacatt tttgttgtcg gcgatgttga tccggacaaa gcagctgaag cagttgggca
     1981 attaccattt gagtcgcggg aaacagttta tccagatctg ttttataccc aacctcaagt
     2041 gaatatcgtg aaggaacgac aagtacgtga gccaatcgtt caagcaaagc tgaacctagc
     2101 ttatcagaca aatgtgtatt acgatgaacc agaacgtttt gcgctaatgg tctttaacgg
     2161 tttatttggc ggttttcctc actctaaact tttcatgaat gtcagagaga aagaaagtct
     2221 agcttattat gcctctagta gcgtggatac gttccgagga ttcatgagtg tccaaaccgg
     2281 tatcgatgaa aagaaccgaa atcaagtact tcatctgatt cacgagcaat tagaaagttt
     2341 gcgaaatggt gaaataacag agttggaact gtctcagaca aaagcaatgc tgagaaacca
     2401 atatctgctt tctctagact ctccgcaagc ggcaatcgaa gcttcttttt tggacagctg
     2461 gctgccggaa acaaaattat ctgatgaaga atggttgaaa cgtatggaga gcgtaacgat
     2521 caaagagata caacaagtag ctgagcaaat cgaattgcag gcaatcttct ttttagcagg
     2581 aggaaatgca aatgaataaa acagaatatg agcaaatcaa tgaaacactt tatcatgaag
     2641 tactgccaaa cggtttgacc gtgtatttgt tgcctaaaaa tgactatcac aagacatatg
     2701 gtttgttcag tacgaattat ggttcgatcg ataacgaatt tattccctat ggtgaaaaag
     2761 aaaaggtgaa agttccagat ggaattgccc attttttaga acataagttg tttgaaaaag
     2821 aagatggtga tgtctttcaa ttatttggga aacaaggagc ttccgccaat gctttcacaa
     2881 gttttacgaa aaccagctat ctgttttcta cgacggatca ggtagaaaag aatctgacga
     2941 ctctgatcga ttttgtacaa gcaccttact tcacagaaga aactgtaaac aaggaaaaag
     3001 gaatcatcgg tcaggaaatc caaatgtatg aagacgaccc taactggcgg atgttttttg
     3061 gcatactaaa taacttgtat cctacacacc cattgcatat cgatattgcg ggcacggttg
     3121 aaagtatcga caaaatcaca gctcaagact tgtatacgtg ctatcggacg ttttatcagc
     3181 caagcaatat ggttttattt gtagttggta agatggagcc tgagaaattg atgaaactta
     3241 ttcgggaaaa ccaagaagca aaaaatttcc ctccaaagca agaaattgta cgttatttcc
     3301 ctgaaaacac aaaagaaatc atcaaacaaa gtgcattgga agcagccatt acacgagata
     3361 aatttgtact tggtattaaa ggattagaca cattgccgca agaaggaaca gaactgttac
     3421 gctataaaac agcaatcaat ctgttgttcc aaatgatttt aggcaatact tctcgaaact
     3481 atctagcgat gtacaatcaa ggaattatcg atgacagctt tggttttgaa ttcagcttgg
     3541 atcgtgaatt tcactttgcg gacttcagcg gagatacgga cgaaccagag aaagcagcag
     3601 aaaaagtcaa agaaatcatt cttggattcg ctgatgatcc ggaagtgtca gaaacaaatc
     3661 tcgatttgct gaagaagaaa atgcttggac aatatttcca atcattaaat tcgatcgaat
     3721 atattgccaa tcaatttacg caaagtttat ttggcgatcg aactttattt gatcttcctg
     3781 aaatcatcga ttcgatccaa atgaaagacg tactggcagc tggggaagca tttataagtg
     3841 aagaggcctt cagcgagttt tacatgagac caaaataaac cagtatttta tgaggaaaag
     3901 tcttaaattt cgttttagac ttgtagtagg aacctcctcc aaaatcagct tttatggtat
     3961 tcttagttgt gttggaaaaa ttagtgagaa aataaaacaa atcatgctct cttttaatca
     4021 acttatatta aaataaaatc aaacgaagta atcaaagagg ttgtgacaga agtggtcagc
     4081 ttcaagaaat aagaaggaat ttacgaaaat tgcttctcaa atttttgtga tatttcggct
     4141 tattgccgaa gaagctactt ctggaacacc gtgtaccaag aggttgtgaa aaagctgccc
     4201 tgcatcaagt aataagaaca gccaagtaaa aacagcttct taatgttttt aacttggttg
     4261 gacttattac cgcagatgca agcttttgaa caccgtttaa ggaagaggtt gtgaaatcag
     4321 cgttttgacc tgagtattag agaaacatac ggaaaaatat ctccttatat tttgccggtt
     4381 tttgagctaa taccgaggaa cagctgattg aacaccgttt aagaaagagg tcgtgagcct
     4441 gccgtttaac tccgagtcac aaggaacaag ttcaaaaaac agcttcttat atttattgga
     4501 tattgtgact tgtgaccgag gagttggcag gagaacaatg tttattcgga aaaaaggagc
     4561 tgtgacatga cttttgtcac agcacccaaa cataacgtct ttcgttgcaa cagcagatgc
     4621 ttcggagaat caaacagact ggagaagatg aacgagtggc ttttgaaacc atcggagaaa
     4681 aattacggca agcacgcctg aataaaaaaa tatctttaga tgaattacag cagattacaa
     4741 aaattcaaaa acgttatttg gaagcaatcg acaatgatga ttttgaccaa ttgcctggta
     4801 aattttacgt gcgggcattt attcggcaat acgctgaagc tgtaggagaa gatggagacc
     4861 atttagtcga tgtttttgat gggaaaagca aattgacagg atcggtccct gaacgtccgc
     4921 agcctgaaac agtaagtact tctagaaaag caatgcatca ggaagaatcg catccaagtc
     4981 gcttttggac aagtcttcct gtcattttat taggattggt tgctttggcg attgtcgttg
     5041 tcgtgggcta tatgacttgg caagatcgtc aagctgatcc aataatcgga gacacagctt
     5101 cttcgcttaa agtagaagga tcagtcgagg agtcctcttc ctcagagcaa agcacgcaga
     5161 ccaaagagtc ttctacagta gaatcaacaa caaaatcaag tgaagaaaag aaaatggcaa
     5221 tagctacagg agaagattct ggcagtgcca tcgcagtaaa tatcacagac gctaccaagc
     5281 ctgtaaccct tgaatttact gctgtcaatc gtgtatggtt aggtgtgcta gtagacaatg
     5341 cctatgttta tcaagggaca ctggcagcaa atgaaacaca gagtaccgtg ttaccggaaa
     5401 cagcaacaaa tgcgaccatc acgattggtg cagcaagcaa tgcaacgatc aaagcgaatg
     5461 gagaatccgt accagttaat ccaggggaaa acaatcagag tccaaaaaat gtgaacctta
     5521 ctcttcaata cgcagaatga tcgtataaat tagtttacgc atctgtttac ttgtaggtat
     5581 aaaaaagaag gatcgtgaca aatctgtgtc gcggtccttc ttcgttaatt caaaaagatc
     5641 aatttcaata aaaatactcc tttgaataaa ttcatttgga aaagtaaata atatcggtgg
     5701 aaacttcgct gatagtcacg tagaataggg aagaaaggag tcgatagtgt gaatttacca
     5761 aataaattaa ctgtacttag aatttgtatg atcccgattt tcattttggt tgtaggttta
     5821 cctttagatt ggggacaatt taacgtagga gacaccacac tggctgtcac acagctagta
     5881 ggtgcagtta tttttgcttt agctagtatc acagactggt tagatggaaa aattgcccgt
     5941 gcgcgaggcc ttgtcactaa ttttggcaag tttgcggacc cgttggcaga taaaatgcta
     6001 gttatgactg cttttatcat gttggttgac caaggaaagg cccctggttg ggtagtagcg
     6061 atcattgtct gtcgtgaatt agccgtcaca ggcttgcgtt tactacttgt cgaacatgga
     6121 gaagtcatgg ctgcagcttg gccgggaaaa gtcaagacgg ctacacaaat ggttgctatt
     6181 atcttgctgt ttatcaataa tatcccattc agcctgatcg gtattccagt agatcaaatc
     6241 atgctttatg cttgtctgat ctttactatc tattcaggtg tggattactt catcaaaaac
     6301 agcggtgtgt tcaaaggatc aatgtaagta tcgtttagtg gagaggttgt gagcctgccg
     6361 tctaactctg agtcacaagg gataatttca aaaaacagct tttcatgttt tatgtatatt
     6421 gtgacttatg accgaggttt tggcaggaga acactgttta tttggaacaa ggagctgtga
     6481 caagattttt gtcacagctc cttgccctct ttttaaataa aaaaatataa aaatacagcg
     6541 tatactatat aagggagcgg gaagtaatga aagcagaaat aatagctgtc ggaacagaac
     6601 ttttactagg acaagtcgtg aatacgaatg ccactttctt gtcagaacag ctagctgatc
     6661 taggtatcga agtttattat caaacagttg taggagataa tcagcagcgt ttagaagagt
     6721 tgattgctct agctgaaaca agaagtgaac tcatactctt atgtggcgga ttaggaccga
     6781 cagaagatga cctgacaaaa gaagcaactg cggctcacct cggtaagtct ctcatacaaa
     6841 atacggaagg atacaaaaaa ttattggcat attttgaaac aacccatcga aaaatgacca
     6901 aaaacaatct gcaacagtcc cagattatcg aaggcggggt tcctctacca aatcgtacag
     6961 ggcttgcttt agggactttt tatcaaacag atacacatgc gtatatcctt cttcccggtc
     7021 cgcctaatga gttgaaacca atgtttgtgg aacaagtacg tcctttacta gaggaacgtt
     7081 ttccttctga agaaaaacta atttctaaag ttttgcgctt ttatgggatt ggtgaatcgc
     7141 gactggtcac tgagctaaaa gatctgattg agacacagat caatccaacg atcgcaccat
     7201 atgccaaacc aaatgaagtg acattacgac tgacagtgaa aacaaatgat gttcaggcag
     7261 ggaatcaagc tcttttagca ttagaagaaa aaatccaaga acgagtaggg gaatattttt
     7321 atggatacgg cgatgataat tcgctagcaa aagtcgtagt ggaactactg aaagaaaaca
     7381 agcagactgt aacagcagcg gaaagtttga cagccggcgc cttccaagcc gcattaggcg
     7441 acattgctgg tgtatctgaa gtatttccag gcggattcgt tacctactcg ctccaaacaa
     7501 aagctggttt tctggagatt gatccggagc tattagcaga atatggaaca gtcagcaaag
     7561 aatgtgtgga gcagatggcc attcaagcac gtgagatagc aagaacagat tacagtgtag
     7621 ctttcaccgg agtggctgga ccggacacgt tagaaggtca atctgcagga acagtatgga
     7681 tcgctatttc atctaaagac ggcgtggttt cggaaaaata tcactttgcc agagatcgtg
     7741 ctgctatcag atataatgcg gttatgcaag gatttgatct tttgagaaaa cagcttttaa
     7801 gaaaatgata aatgcgaata tttgttcggt tttttcttgc tttttttcac taaaaaagat
     7861 atgataagga taatgaaatg ttgctctgat ttgtaaatat aaggaggatt atcgtattgg
     7921 cagatgatcg taaagcagcc ttagatgctg cactgaaaaa aattgaaaag agctatggta
     7981 aaggctctat tatgaaattg ggcgaaaaaa tcgaccaaca aatctctaca attccaagtg
     8041 gctctcttgc gttagatgtc gctttaggtg tcggcggtta cccccgtgga cgtatcatcg
     8101 aagtatatgg acctgaaagt tcaggtaaaa caacagttgc actacacgct attgcagaag
     8161 tacaaaaaaa tggcggaacg gccgctttca ttgatgctga gcatgcgtta gatccgcaat
     8221 atgcacaaaa attaggtgtg aatatcgatg aactacttct ttcacagcct gacacaggag
     8281 aacaaggtct agagatcgct gatgctttag tatcaagtgg ggctgtagat atcgtagtag
     8341 tcgattcagt tgctgcttta gttccacgag cagaaatcga cggcgaaatg ggtgactcac
     8401 atgtcgggtt acaagcacgt ttgatgtctc aagcattgcg taaactctct ggttcgatca
     8461 acaaaacaaa aacaatcgct attttcatca accaaatccg tgaaaaagta ggcgtgatgt
     8521 ttgggaatcc agaaatcact cctggaggac gcgcattgaa attctacgca acgatccgtt
     8581 tggaagtacg tcgtgcagaa caattgaaac aaggtacaga tattgttggt aaccgtacaa
     8641 agatcaaagt cgtaaaaaac aaagtagcac ctcctttcaa aatcgctgaa gtagatgtca
     8701 tgtatggttt agggatctca caagaaggag aacttctaga catggcagta gaaaaagaca
     8761 ttgttgataa aagcggtgct tggtattctt ataaagaaga tcggattggt caaggacggg
     8821 aaaacgctaa aatctatatg gctaatcatc ctgaaatgat ggcagaagtt tctgctctag
     8881 ttagagcagc ttatggtatt ggtgaagaag tcgctgtccc agaagatgaa aaaggacaag
     8941 aagaattgcc tttagtagaa gaataaaaat tatgataaac aaaaacggct ggtctgaaga
     9001 gtaggtactc tccttgacct gccgtttttt tattgaataa agaaatcgtg agttatttaa
     9061 ttatacgagt gggtacataa aataaaaata tctgttcatc tacaaagaat aatttaatag
     9121 aaaagtttct caatttaaag gtttacctat atgaaactag tgtcatttat tttaaaaacc
     9181 atcgtttaat gaataagtag aaagccgttt ctttgtttat ttaaagttga cactacgggg
     9241 tacaaacatt agaataaagt tgtgcatgtt ttttgtacac atatatgcga agatgcatat
     9301 tgacgagttt agaataattt atcatagaag ctgtatagat gataaaaatg aaaaagatag
     9361 tatggaggtg gattttatgg tattcaacat tctcctcgct atcatcggtt taattgtcgg
     9421 tcttggttta gggtttatgg tcgcaaagtc acgtcacgag aaagaaatag ctggtgcaca
     9481 atcatcagct gctggaatca tcgatagtgc aaaaaaagaa gcagaaactc taaaaaaaga
     9541 agcattgtta gaagctaagg aagaaaatca gaaataccgt tctgaagttg aaagtgagct
     9601 gagagaaagt aagttagaat taaaatctca agagaatcgt ttgattcaac gcgaacaaac
     9661 gctgaatcgt aaagatgact cgttagaaaa acgcgagaac tcacttgaaa gtaaagaaga
     9721 agcacttagt tcaaaacagc aattaattga agagcgagaa aaagacgttg aaaaaatgat
     9781 tgaagatcaa caaaaagaac tagaaaaaat tgctggttta tcaaaagagg acgcacgaga
     9841 tgtcatcatg aaatcgactg aagaagagct gaatcatgag ttaactctaa tggtaaaaga
     9901 atctgaacag cgtgccaaag aagaagcaga tcgcaaagcg aaaaacttat tatcattagc
     9961 gattcaacgc tgcgcagcag atcaagtttc agaaacgact gtttcagtcg ttacccttcc
    10021 gaatgatgaa atgaaaggtc gtatcattgg acgagaaggt cgtaatattc gaacgcttga
    10081 gacgctgact ggtatcgatt taatcatcga tgatacaccg gaagcagttg ttctttccgg
    10141 attcgatcca atccgaagag aaatcgcacg gatgaccttg gaaaaactga tacaagatgg
    10201 acgaatccat ccagcgcgta tcgaagaaat ggtcgagaaa tctcgtaaag aaatggatga
    10261 acgtattcgc gaatacgggg aagaggcagc gtttgaagtc ggtgctcata cacttcatcc
    10321 agatctaatc aagatcatcg gacgtctgcg attcagaact agttatggac aaaacgtctt
    10381 gaagcattcg gtcgaggttg caaaattagc tggtatctta gcagcagagc ttggcgaaga
    10441 tatccaatta gcaaaacgtg ccgggttgct ccatgatatt gggaaagcac ttgaccatga
    10501 gattgaagga tctcacgttg agatcggtgc ggaattagct gccaagtaca aagaaaaccc
    10561 agtagtaatc aacgcgatcg cttctcatca tggagatgtg gaagctactt ctgttatctc
    10621 tgtccttgta gctgcagcag atgcgctctc agcagcaaga cctggtgcgc gaagtgaatc
    10681 attagaaaac tacatccgtc gtttaagaag tctggaaaat atttcgaaca gcttcgccgg
    10741 tgtagaatca agttacgcag ttcaagctgg acgcgaagtt cgggtaatgg tcaagccaga
    10801 agaaatctcg gatttagacg ctgttcgttt agtacgtgat attcgtaaac gaatcgaaga
    10861 agaactggat tatcctggac acatcaaagt aatcgttatt cgggaaactc gtgcaactga
    10921 ttatgctaaa taataaaaaa tacaaaagaa gagccgcggc aaaagccaca gctcttcttt
    10981 ttttgtaagg tacgaaaaaa cattgctatc attatttttt attcaacatc tcaagatctt
    11041 tctcgatcgt cgtattgatt cctttgatga ttgctgggat gaatcctgct tcttctaagg
    11101 caactacacc tgcaacagtt gtaccgccag gagaagaaac ttggtctaca agttcccatg
    11161 gatttttatc acttgaaagg aatttttgac aagaacccat aattgctttt gcagcaatct
    11221 cagtggctgt ctgtttggac aaaccattca gtacaccagt ccgtcccatc gcatcgatca
    11281 gcatgtaaac gaatgcgggt gagctgccag caaggccaat gaatgtactg aaatctgatt
    11341 ctgctaaagg atagacgctg ccgattgctt caaaaatcat cgtagcttgc tgaagctgtt
    11401 cctccgtggc agcttcattt ttgcaaatcg cagaaacgcc tgctcctacg ctgacattga
    11461 cattcggcat cacacgtacg atggaggcct gaggatcttc aagcgctgtt tctaaatctg
    11521 ttaatgattt tcctgaagca atagaaatga ataagacttt ctggctatat tctcttagtt
    11581 cttccaatac tttttcaatg atttttggtt tcacggctaa aagaacgata tctgattgtg
    11641 atgcaacttc ctgattactt ttgcatgcat ggacgccagt ttcagcagca aatttttgtg
    11701 cattttcaaa atgtccactg gaaacgaaca cctcttcttt cgagactgtt ccttttttta
    11761 ataaaccatc aataatagct tgtgccatat tccctgtgcc gataaatcct actttcatgt
    11821 tatcctctcc tttagcatta ggatatcttt ctttttctat catcgcaagc aaagaacagg
    11881 tctaaagtgg aaaaattaaa ataaataaga taacattggg gtatgacaca aaagtataca
    11941 agttaggaat gggaaaatgt gaaaaataaa cgatacttga tgctgcaatg gataaaggaa
    12001 catagtctga ttttaaaact gatttttttc ggctccgtgt tagtctttgt ggcaaatcaa
    12061 gtcgcaaata ttgctaatgg catgagttgg caagatattt ggcaaaggat gggacaacaa
    12121 agccgcatga cgatcctgct catgattctg gctggactgc tgggtgtcac tccgatgttg
    12181 ttgtatgatt gggtgacgat cagagtctta gaaaaacaag gaaaaccaaa aatggaaaga
    12241 aaagagtttc ttcttgctgc gtgggtaaca aacacgatca acaatctcgc cggttttggt
    12301 ggtgtggtag gagcaagtct gcgggctagt ttttatggaa agcagacaaa tagaaaaatg
    12361 gttttagcca ctgtatcaaa agtcgcacta tttatgctga ctggtttgtc tgtatggtcg
    12421 tttcttacat ttattgatgt cttttttatt cagtcagaaa gtatttttcg aagctattgg
    12481 atctggcttt tcggcggtag ttttttagca ccagtcattt tcttttttgc ttatctaaag
    12541 agaaagacat tgttcttcga gttttatcca aaaggcttgc ttggtctgct actggcatcc
    12601 tttggacaat ggacgggagc ccttgcggta tttttgatca tcggcaagtt gatgagaata
    12661 gatatttcga tgctttcgat ctatcctatg ttcatgattg ctacattgat aggaatgctg
    12721 acgatggtcc caggtggaat ggggactttt gacgttttga tgatcttagg aatgagtcaa
    12781 ttgtctgttc ggcaagatgt agcagtagtt tggctattat attatcggtt gttttattat
    12841 gttctacctt ttatgacggg acttctattg ttcatcacac atacaggagt caaaatcaat
    12901 cgatttttag ataacattcc gcgactgttt ttccaaaagg ttgcgcatat cgtgctcgta
    12961 agtgctgtct attttgcggg gatcatgatg gtacttctat caacaatcac taatctgtct
    13021 gcaatcagtc ggctatttca agtattattg ccgttctcat tcaatttttt agatcagaca
    13081 gtgaatctat tggttggctt tttattactc ggccttgcta gagcactttc agtaaaagtc
    13141 aaaaaggcat ttctgcctac gattgcttta ctatcttttg gtattttaaa tacaatcaca
    13201 cgtacgttat cttggcagtt gatattggta tatgtcttga ttctgttagc tgtgtggtta
    13261 tccagaaaag aattttatcg aacaaaattc gtttattctt ggggagctat aatctttgat
    13321 gctagcttgt tcggcttttt gtttatcgtt tacgcaattg caggctatca cagcggacgc
    13381 tttttagtcg gtcgaataac aggaaatcat tttattttgt ttccttcaga tgatgtgtgg
    13441 ttctcagggc ttattggttt gggcatctca ttgctagctt tagtggcgct ttatcaatat
    13501 ttagctgaag atactacgaa gcttggcagt gagtacgaaa aagaccgttt tgaccgttta
    13561 ttggaaacat acggaggcac agctacaagc catcagcttc gcttgtcagg ttacagttat
    13621 ttttattacc aagaagacga ccaagatcaa gtcgtttttg gttatcagat caaaggaaac
    13681 aaatgctttg ttttaggaga tccagttggc aatcctaaaa tgatgcgggc agcaacgaat
    13741 cagtttatga aacaagcaga ttgtttaggc tatcagcttg cgttttataa gatatcagaa
    13801 agctacgtag tgatgcttca tgaattgggt tttcacttca cgaaagtagg tgaagcaggg
    13861 attgttgatc tagcaacaga agacttgtct cggctgagtc agcaacttga atatcaacgt
    13921 ttgatgaaag aaggatacca ttttacttgg tacgatcaac tgccggaaga attacatcaa
    13981 gctgtaaatg aagtttcaca aaaatggctt caaggtgcac gagaaaaata cttctctgtg
    14041 ggacgatttg ataaatcata tgtattatct agcggtgtcg gtattgtccg taaagatcaa
    14101 aaagtcgttg gcttcatcac cgctcagccg atgacgaaga agcaggcggg atatgatttg
    14161 ttgcgggtct tacctaaaga atctgaggaa ttagctgact atctgttagc caatctgttt
    14221 attgtatacg agaaaatggg ctactcggaa gccaatctag gcttagctcc attagctaat
    14281 gttggagaaa cagatttttc tttctttcaa gaaaaagtca tgcatatcgt atataattat
    14341 ggtaattttt tctattcctt ccagtctgct tatgaaaaga aattaaaata tgtcgatcat
    14401 tgggaaggac gttattttgc ttataggaaa ggaagtaatt tcggatttgc taccatgcag
    14461 ctactcagtc tgataggaaa agaaaaagga aatgttccga gtttggcaga agaagtgctc
    14521 acagaattat aagaatcact agaacttgtt tggattatga agagaaaatt ctgtgaaagc
    14581 tgttgaaacg atgacaaaat caaccactag gcagacataa gctatacttt tatttttccc
    14641 tatgatagaa tacttgcgac ttagactttt cgaatgggtg agaggatgga attgattgaa
    14701 aaagcgccag ccaagataaa tttaggactg gatgtattat atagacggca agatgggtat
    14761 catgagttgg aaatggtgat gtcgagcgta gacttggcag atcatctatt ttttgaagaa
    14821 ataacagaag acaaaatcat tgtagaaaca aataaagcat ttttaccggt agatgaacgg
    14881 aacaatgttt atcaagctgc tttattgcta aaaaataaat acaatatcaa aaccggtgtc
    14941 aagatctttg ttaagaagaa tattccagta gcagctggat taggcggagg aagtacagac
    15001 tgtgcagctg ctctaagagg gatcaaccaa ttatggaatc tgggctgttc gttagaagaa
    15061 ctggcagaaa tcggtttgga agtcggtaca gatgttcctt actgtgtcta cggaagtacg
    15121 gcatttgtcg gtggcaaagg ggaagaaatc caagtattac cttctatgcc acagtgctgg
    15181 gttgtgttgg tcaaaccaag aatgagtgtc tctacacgta cagtgtttag agaagtagat
    15241 acgcaagcca tccaacatca agacatccac ggacttgctg aagccatccg agagcaagat
    15301 tatcagcaga tgatcaaaaa aatgggaaac agtttagaag atataacggg aaagcggcat
    15361 ccagtcatcc atcaaatcaa agagcgtatg atcaagtacg gagcagatgc tgcattgatg
    15421 agtggaagcg gaccaaccgt ttttgccttg tgtcaacatt attcaagagc gcagagagta
    15481 tataatgggt taaaaggttt ttgtgaggaa gtttatttag tacgaaccct gcaataaaat
    15541 ataagaagta aaataggtga tgaaaaactg aggaatccta aaatggtatt cttcagtttt
    15601 ttattgtagt gaaatggcta gatatgagca gcaactcatc cattttacga tttaatcaag
    15661 aatatacatg cttaaatcag aaattgatgg atttctattg actgtgtttt tttattttga
    15721 tacattagtt cacgttaata aatcgtaaaa ttccgatttg ttcattgaaa ggagcatata
    15781 aatgaaaaaa tatcttttga cagctacggt aatgataggt gctttactgt ttgcagcatg
    15841 tggaaatacg aacaaggaag cagacaaaaa agaggatttg acgatcgtta cgacttttta
    15901 tccgatgtat gattttacaa aagagatcgt aggggatgaa ggaaacgtga aacttttgat
    15961 ccctgctgga acggagccgc atgatttcga accaagtgca aaagaaagag cagaaatttc
    16021 cgatgcagat gttttcgtgt ataatagttc agacatggaa ttttttgtgg attcgttaaa
    16081 ggattcagtg gatagcaaac agaccttgat gatcgaagca gctaaaggaa tcgaccgttt
    16141 agaatcgcaa gaagcagacg aacatgaaga atcagaagaa gggcatggtc attcacatga
    16201 atacgatcca catgtttggc tcgatccggt attagctata aaagaagtca gaacgattgc
    16261 tgaagaatta ggcgaaaaat atccagataa aaaggaaact tttacgaaga atgccgatgc
    16321 ttatatcaaa aagcttgaag cactggatca aaaatactcc gatgagctaa aagatgcaac
    16381 aaaccgcaca tttgtcactc agcatgctgc ttttgcttat ttagcgaatc aatacgactt
    16441 aaaacaagta gcgatttcgg gcgtttcacc agatcaggaa cccacaccaa gtcgcttagc
    16501 tgagctaaaa gaatttgtga agaaaaacaa catcaaagtg atttattttg aagaaaatgc
    16561 ctcttcgaag gtagctgaga cattgtcgaa tgaaacagga gtgaagctag aagtgttgaa
    16621 tcctttagaa agcttgacta atgaacaaat caaagcaggc gaaaattata tttctgtcat
    16681 ggaaaaaaat ctgaaagctt taaaagaaag tatcaattaa gttttagaat ggaggttgta
    16741 aggtgcgtta tatcgaaata tctgatttga ccttttacta tgatgatgaa cctgtactag
    16801 aagatgtctc ttatcatgta gatgcgggtg aatttgtcat tttaactgga gaaaatggag
    16861 cagccaagtc aaccttggtg aaagcatcgt taggattact gaaaccttca aaaggaatga
    16921 taaagattgc tgagaaaaat caagaaggaa aaaaattaag tatcggttat attcctcaac
    16981 aagttgcatc tttcaatgca ggttttccta gtacggtgat cgaattagtc cgttcaggaa
    17041 gatatccaag aggccgctgg ttcaagcgtc tctctgaaaa agatcatcaa catgtacagc
    17101 gtgctttaga agctgtaggg atgtgggata tgcgaaatcg gcgaataggt gaattgtctg
    17161 gcggacaaaa gcagcgaatc agtttagcgc gtatttttgc tactgaccct gacttatttg
    17221 ttcttgatga accaacaaca ggtatggatg aagaatccag aaatgaattt tatcgtcttc
    17281 tccgacatag tgcgcatgtc catgggaaat cagttctaat gatcacccat gatcatgaag
    17341 atatcaaaca gtatgcggac agacagatcc gactggtgag aaaggaggat tctcaatggc
    17401 gttgctttca tatgaattca tgagaagagc gtttcttgcc gctatcttca ttgccggaat
    17461 cgccccgatg ctaggtgtgt ttttagtgat cagaagacaa tcgctgatgg ctgatacgct
    17521 ttctcatgtc tctttagcag gggtagcgtt aggattcttt ttgaacctta atcctacact
    17581 tacgaccatg ctagtcgttg tattagcagc tgtgatattg gagtatctgc gaacgatcta
    17641 ccgaacctat tcagaaatct ccattgccat tttaatggct ggtggtttgg cgctagcgtt
    17701 agtattgatg aatttgagcg gagggaattc agcaacaagt atccaatcct atctgtttgg
    17761 ttcgatcgtg accattacat gggagcaagt catcttttta ggaatcttat tcgttgccat
    17821 cggtatattg ttctttttat tcaaacggcc gatgtatgtt ctgacttttg atgaagatac
    17881 cgcccacgtg gatgggctac ccgttcattt gatgtcgatg atgttcaatg tgattactgg
    17941 tgtggctatt gctgtgatga tcccgattgc cggtgcactt ttgatatccg caatcatggt
    18001 tcttcccgca gcaatcggta tgcgattagg caaaagcttc aatgtcgtga ttgctatcag
    18061 tgtttgtgta ggatttctag ggatgctgtc aggactaact agctcgtttt atctagatac
    18121 acctccagga gcaacaatca cattagtctt tattgctttg ttcctgattg taaatatcat
    18181 caaacgaata ttggttgcct tcagaagaaa aaataactaa attataaaga aaagaagcct
    18241 tataaaaacg aaaaattttt tataggcttc tttttatttt aataaatacc gaactatttt
    18301 cttatttttt cataaaatgc tcgaattttt gaagaaaaac ttatataatg taaaacgata
    18361 aaatttctta aaaggagttg gaataggtga aagtacgtcg cagtgaacgt ctagttgaca
    18421 tgacacagta tttattgaat cacccgcatg aattgatttc cttaacaagc tttgccgaac
    18481 gttatgaatc tgctaaatct tctatcagtg aagatttggg aatcatcaag aaaacattta
    18541 aagaacgagg gtatggaacc ttggaaacaa tcccgggtgc tgcaggtggt gtattgttca
    18601 tccctgaaat ttcatatgaa gaggcgaaaa aatatattga atctctagca gaacgtctat
    18661 cagaacaaga ccgtctgctt ccaggaggat atgtttatct ctctgatttg ttaggagaac
    18721 ctgaactgct gcgtcaagtt ggaagaatca ttgcttctaa ataccttggt gaaaaaatcg
    18781 atgctgtaat gactgtagcc acaaaaggcg tacctattgc ccaagctgtg tcctattatc
    18841 tgaatgcgcc attcgttatt gtacgccggg actcaaaaat aacagaagga tcaacagtaa
    18901 gtgtcaacta tgtgtctgga tcttctgaaa gaattgaaaa gatggaactg tctaagagaa
    18961 gtttgaaacg tggttcacgt gtccttgtag tggatgattt catgaaaggc ggcggaacag
    19021 tcaacggaat gaagagcttg attgaagaat tcgaatcaga acttgttggc atcactgtat
    19081 ttgccgaatc aaaattcaac ggtcatcgcg ccatcgatga ttatacgtca ctgctttatg
    19141 tcaaagatgt agatactcaa acgaaaaata ttacggttgt gccaggaaat tatttttcag
    19201 aataagaggt tgtgaaaaag ccgcttagtt tcgagtagta agaaaaattt tgtgaaaatg
    19261 gctttccaca ttttttcata aatttggctt aataccgaga aactggcttt tgaacaccgt
    19321 ttatctagag gttgtgaaat cagcgtcctg tcctgagtat tagctcaata aacggaaaaa
    19381 ttgctcctca tattttgccg tttattgagc taataccgaa ggtcagctga ttgaaaaacg
    19441 tttaatgaag aggttgtaag cctaccgttt aactctaagt cacaagaaac gatttcaaaa
    19501 aacagctttt catgttttat gagtagtgtg acttgtgacc gaggagttgg caggagagca
    19561 ccggttacca aatagatagg cccgttatgg tctatctatt tttttatcca gaaaacgctg
    19621 ggataaaaga aaatcacttg ttttgttgaa aaaatgggta tactgggata aactgaaatc
    19681 agcaaactat atttaggagt gacgcagttg gacgcacgtt atgcaattat tttggcggca
    19741 gggaaaggta cccgcatgaa gtcaaaatta tataaagttt tacatcccgt ttctggtaaa
    19801 cctatggtag aacatatcat taatcgggtc agtgaaacga aaccagatga agtgattacg
    19861 atcgttggac acggagcaga acaagttaaa gcacaactag gagaacgcag taaatatgcg
    19921 ttacaagcag aacaattggg aacaggacat gctgttttgc aagctgcttc tttcttggaa
    19981 ggaaaaaaag gaacaacgtt agttatcagt ggcgatacac cattattgac tactgaaacg
    20041 ctgaacaatc tttttgaata tcaccaagga aaaaatgcaa gtgcaacgat cttgacggca
    20101 caagcagaaa acccaacagg atatggacga atcatccgtg accatattgg gatcgtagaa
    20161 aaaatcgtgg aacaaaaaga tgcaacacca gaagaagctc ttgtacaaga aatcaataca
    20221 ggaacttact gttttgacaa cgaagctttg ttcgatgcgt taagcaaagt tggaacaaac
    20281 aatgctcaag gtgaatacta tctaacagat atcatcgaaa tcttaaaaga agaaggccat
    20341 acagttgctg cttatcaaac ggatgatttt gaagaatcaa tgggagtcaa tgatcggatc
    20401 gcgttagcta aagcaaatga gatcatgaga aagcgaatta accagatgca tatggtcaat
    20461 ggcgtaagct ttgtcgattc agcaacgaca tacatcgatg caggcgtaga aatcggtcca
    20521 gacacattga tcgaagcagg tgtacaaatc caaggaaata cagtcattgg ttctgattgt
    20581 gtcatcgggt cacattcaaa aatcgtagac agtaggattg aggatcacgt cgtcattgaa
    20641 aactcagtca ttgaaagcag ccatgtcaag aaacatgcag atgtgggacc ttatgcacat
    20701 ttacgaccaa aagctgaaat tggcgaaaac gtccatatcg gaaactttgt ggaagtgaaa
    20761 aatgctcaaa tcggcaaagg aactaaagtc ggtcacttga cttatgttgg tgatgctacg
    20821 ctgggagaag aaatcaatgt cggatgtggt gttgtcttcg tcaactatga tggaaagaac
    20881 aaacatcata cgactgtcgg cgaccacagc tttattggtt ctagcacgaa tatcatcgga
    20941 cctgtcgagg tagctaaaaa cagttcgatt gctgccgggt caacaattac agacaatatt
    21001 ccagaatatg cgctggcaat tgcgagagca agacaagtca ataaagaagg atatgcaaaa
    21061 aaactccctt atctaaacta agacttttgc aaaatcactt gatttattta aaaaatatga
    21121 ctactattta ttaggtagaa ttctagagtt gtgaaaaaga aagtggaggt ccccatgtca
    21181 aaacattact ttgacccaag attaaaaatt tttgcgttaa attccaatcg cccattagca
    21241 gagaaaattg cagcagcagt cggcgtcgag ttaggaaaat catctgttac tcaatttagt
    21301 gatggagaaa ttcaagtaaa cattgaagaa agtattcgtg gatcgcatgt ctatgttatt
    21361 caatcaacga gcagcccagt caatgataac ttgatggagt tgctgatcat gattgacgca
    21421 ctgaaacgag caagtgcaaa aacaatcaac gtagtcatgc cttattatgg ctatgcgcgt
    21481 caagaccgta aagcacgtgc acgggaacca atcacagcga aattagtagc aaacatgatt
    21541 caaaaagctg gtgcaacaag aatgctgact ttggaccttc atgcagtcca aatccaaggt
    21601 ttctttgata ttccagtcga tcatttgatg ggtgcgccac ttattgccaa ttatttctta
    21661 gaaaaaggaa tcaaaggcga tgatgttgtc gttgtttcac cagaccatgg tggtgtcaca
    21721 cgggcacgta aattagcgga atttttgaaa tctccgattg cgatcataga caaacgccgt
    21781 ccaaaagcaa atgttgcaga agtaatgaat atcattggac aagtcaaagg caaaacttgt
    21841 gtactgatcg atgatatgat cgatacagca ggtacgatca cattggctgc caatgctttg
    21901 aaagaagctg gtgcaactag tgtgtatgct tcatgtacac atccagtatt atccggccct
    21961 gctttacaaa gaatagaaga ttcagctatc gagcgtctag ttgttacaga ctcgatctat
    22021 cttccagaag atcgtaaaat cgacaaaatc gatgaagtaa gtgttggcgg actaatggga
    22081 gatgcaatca aacgtatcca tgaaaacaaa ccagttagtc cattgtttga aacaaaaaat
    22141 aaataataaa taaactcaca aaggggagtc caattgggct gagattgaat ctatttctaa
    22201 acccttcgta cctgtatcgg ttatgcgagc gtaggaattg tgaataaaca gctgtttgac
    22261 tattttcgaa agctgcttcc tcctttgtga cttttttatt caaaggagga agttttttta
    22321 tgggaaaaaa tagagtttgg gtagaaggaa cgattgttgc agcgttagcg atggtgttgt
    22381 cgttgattcc gatccagatc ggcagcagtt tttctatttc attagggcag attccattga
    22441 ctctttttgc gttaagaaga gggacaaagg cagggatgct ggcaggtttc atttggggca
    22501 tcctacattt tccgttggga caagtttatt atttaagtgt cgttcaagtg ttgattgagt
    22561 acccgattgc ctatactttt gcaggcgcag cagggctcat ggcttcaaat gtccaaaaag
    22621 gctatgtaga cgataatacg aaacaaatta gaaaaagcat cgtgtttggt gcattgattg
    22681 gcgcactttc cagatatttt tggcatttta ttgcaggagt ggttttctgg ggagcgtatg
    22741 cactatgggg gatgaattct tggctctttt ctttcgtaat gaatggtgcc agcgggttga
    22801 gtacagctat tgtaacgatc atcgttttat tagggatcca acaaacgact ccttcgattt
    22861 ttgtgccaga taaacgacag gagctgtaaa taaaaaagaa gcaagaaact tgagacagaa
    22921 tcatgtccta gtttcttgtt tcctttttat tttttgataa gaaatagatc tacttcaatg
    22981 gcagataaga aagatcggca tcttctacca attgccagtg tcgatcggtg acagagtaga
    23041 ttaaagtagc gatgatttcc tcttctcgat accgggtgcc ttttaatttc caaatataat
    23101 cttcaatcac atagattggg atacgatatt taccatcgat caaaccaact tgatcaaaag
    23161 aaaaaatgat cccttcctgc atcaaattac gcatttcttt caataattcc acactgattt
    23221 tttcaacagg tgtttctttt ttgaaaaaag atttttttac attgatctta tctgacaaga
    23281 tcgaacttaa tttactagca aaaatcctat aaaattcatc taaatagcga taataaatcc
    23341 gattcagctg atcattaaga tcgaagtata caaaattatt ctgtagttta taaaaaaacg
    23401 gcgaatgaag atgtgttttc atatgaccaa aatataataa ttctgaaatt tctaaaggtg
    23461 tcaattcttt cagcatcgtt aaatcagtaa agtcgatcca cttcaattca tcgaatccac
    23521 gcctgttacg agaagaggaa aagaaacgct gaatattttc tgtaccacgg attactttca
    23581 gccctgtatg ggattcatat tctccagcag aagcagatgg atcaagcaag agcaagtttt
    23641 gaggaaaatg cacgatactg tttgcaaagt cagtagcagt cagccctttt gttaaaacag
    23701 cattacttgt ggtatcaata tgtacataaa ctgactcagt catcatgttc ctcctcttat
    23761 ttcctcttaa tctcttttat tttacaacat ttgcattaaa aaagcttgtt tcttttattt
    23821 taaaattcca ttacaaaatc acgttttcat tgaaaacact ctcattttca attaattttt
    23881 gtgatttttg tattttttat ttaaaggatg ttttatgaat tgttttctta tggaatctac
    23941 aaagtcgaat acgagactca tgaccttttt atgacgtact ggtatacttg aagaaaaagg
    24001 agagcgcgat ggagataaaa aaagtttact tttcacagaa aatgtcgctg tattcgccta
    24061 tccagcaagc aaaacaaccc cttccatttt ttcaaagtca tcaagaaagt agagacgctt
    24121 tttggcgttc tgcaaaaaag caatgtgctt ttaaagcagt atcgaaaaaa tataccgtct
    24181 attttactat tgctaaaagt agaggagatg ttatttttaa taatctgttg attgaaggtg
    24241 aaacttttga atggaaaaaa ttttttcggt atatggaagc ttgcgctcgt ttttttatta
    24301 aagaaaactg ttgtttttta tttcaatctc ctctatcaga agaatggttg cgtatttttc
    24361 ataaaaacgg ctatcaagga accacacaat taaataaaaa gctggtctat catacagcac
    24421 ttgttttagg tggaggagga gcacacggtg cttatcagat tggtgtgtgg caggcgctga
    24481 aggaacatga tatcaacttt gagattatca caggtacctc ggtaggtgcg ttgaacggcg
    24541 cattgatttt acaaggagat atgaaaaaag ctgtgaattt atggaaaaag ctgtcgacaa
    24601 gacaagtgct tgcgttacca gaaatggctg cagttgaaga ccttcgtgaa cgcttctatc
    24661 gagaaagacg ccaaatgacg aaaacagcac taattgaagg cggggtttct tctgctccat
    24721 tggaaaagat ggtcaaagac aatttggatt tgtccttact caaacataat cccaaaatac
    24781 gtttatatac ggtgtctact aaactgccag aactagcgga agtagtgact gatatccaac
    24841 agacaaaaac agaagaaata ccagattgga tactcgcctc tgcttcattt tatcccgcta
    24901 tggcttatcg aaagatcgga aaaaataaat atgcagacgg tgggtatcgc aacaaaatac
    24961 ctattgatat tgcgattaac aaaggagcaa cagaggcatt tgtcgtagat gtgcaagggc
    25021 caggcccagc gaaaaaaatt cgtatgccag acatttttat ccattggaaa tgtcaaacat
    25081 tgtggacact aggcagcttt ctgctttttg atagccaaag gaaccaatta aatttacaat
    25141 taggctatct ggaaatgaaa aaacgattag gctattacta tgggaactgg tatacatttc
    25201 attctgttaa acctgcaaga acatactggc gaggattttt gtcttactta acaaaagaaa
    25261 ttcagttaga attatctttt ttcaaaagca taaaattttg gcaaaaactg cgtaatttat
    25321 ataagaacag ggtcgtacca gagacatgcg gattggcgat gctagaactt ttagcaaaaa
    25381 aacatttttt actgcccaat gaaatctatc aagtagacat gatgattcaa atgatctgcc
    25441 aacaagatat aaaaagtatg ccggatgatt tattggcaca aattggtcaa ttaagtactg
    25501 aagaatggcg aaggtatcga aaataccagc aaaaaataca aaatgagcgc acgaaaactg
    25561 tttattttga ttatctgcta caaggaaaac gcaaggatcg tttgcagcat gaattgctta
    25621 agcaaccagt tgacacatta ctgatcctat atttatatta tctcaaggag gaacaaccat
    25681 ggcacaagaa ttttcatatg aaatcgtaga agaaatcgct atattgtcag aaaacaacaa
    25741 ggggtggcgt aaagaactga acctagtcag ctggaatggt cgcccgccaa aattcgatct
    25801 tcgagattgg gcgccagacc atgaaaaaat ggggaaaggc ctgacattga cgaacgaaga
    25861 gtttgaacaa ctgcaaaaag caatagaaaa tatgtaatga ggaaggaccc tgtcgaatga
    25921 aaagtatgac tggttttggc aaagccatcc gcgaaacaaa agcgtatcag ttagatattg
    25981 aaataaaaag tgtcaaccag cgttttctag atgttcaaat acgaagtcct aaaatcctga
    26041 actttgttga aaacgatttt cgtcagctta ttaaacagca gttaagccgc ggtcgaatcg
    26101 aagtatttgt gaatctagct tatattggca aaaacgaaaa acagatcgtc atcaactggg
    26161 aattgattga ttcacttatc actcaattga cagacggaat tcaacaacga tacggtagtc
    26221 aaaatcaagt gtcaattagt cggatggcgg aacgcttcgc gctggacgaa aacttcgtaa
    26281 cggtagaaga aaaaccggaa gagagcatgg aagaattggc acagttagct ctagatacat
    26341 tgaaaagcgc acttgattct attgaggcga gtcgagaaaa agaaggtcaa gctttagctt
    26401 tagtgttgaa aaagaatact gaagaattca aagaagtact aaaaaaactc gatagttttg
    26461 tagaaatcta tgaaaaggaa tttcaaataa ggtatcaaaa aaagctggag gaatttcttg
    26521 gagcgaaagt cgatgagcaa cggttgttga cggagctagc catcttgttg gaacgcggag
    26581 atattcacga ggaactggat cgtctggcga tccatgtaca aaaactagat gaacttatcg
    26641 aagcacaatg tcctgtaggt cgggaattag atttcctgat ccaagaaatg aatcgggaaa
    26701 tcaacacgat cggttccaaa tcaaatgcaa tcgaaattaa aaatcaagtc gtccagtcta
    26761 agacgatctt agaaaaaatc agagaacaag tacaaaatat tgaatgacga aagaggtaga
    26821 gataatgaaa tattatgacg taacgttcca cgaattaagt ggaaaaactg tggttaaacg
    26881 ggatatccct tctgaaaaaa acggctttga cgtatggaaa gatgcctgtg cagactataa
    26941 tgagaacgaa ctgtttattt tgatcaacga cggtgcttac gtgacgatga atcggaaatt
    27001 tattgttcga attgacacag aagaggtaga agatccgaca gaaaaagcac gttctcgaaa
    27061 agatgagatc atgggtgtag tgaatacttt gtccaatatg ggcttttagc aaggatgctg
    27121 aacaaagaaa tacaataaat aatcagaatt ggatttcttc gcttagcttc tttgctctag
    27181 gaatacattt aaaggttgtg acaaaattcg tgtcacaatc tttttttatt ttgaataagt
    27241 gatgttcaaa aaccattttc tcggtattaa gccaaattta tgcaaaaatg tgagaaacta
    27301 ttttcacaaa atttttcttc atactcgaaa ctaatcggct tcttcacgac ctcttataca
    27361 cggcgttcaa aagcttgcat ctgcgataat aaccccaacc aaacgaaaaa catgagaagc
    27421 tgtttatgtt tggctgttct tattacttga tgcaggacag cttttttacg acctcttggt
    27481 acagggtagc ttttttacca atttctagct ataattaaag ataaccttga aagttgcaga
    27541 aaaaaagtgc aaaataaacg ataagtacaa aaagactagt tgaaaggacg tcgtcatgtc
    27601 agagcgtgga ttattaatcg tgttgtctgg tccatccggt gtaggaaaag gcacagtacg
    27661 aaaagcaatt tttgagagtg aggataatga ttttcagtat tcgatctcaa tgactacccg
    27721 taaaatgcgt gaaggggagg tcgaaggcgt tgattatttc ttccgaagca aagaagagtt
    27781 tgaatcaatg atcgaagctg gagagatgct ggaatacgca gaatatgtcg ggaattatta
    27841 tggaactcct ttgtcatatg tcaacaagac attggatgaa ggaaaagatg ttttcttgga
    27901 gattgaagtc caaggagcaa aacaagtcaa agaaaaagtg cccgatggtg tattcatctt
    27961 tttgactccg ccagatttag cggaattaaa atcacggatc gtaggccgag gaacagatgc
    28021 agatgaagta atcgaagaac gaatgaaagt tgcaaaagaa gaaatcgaaa tgatggctct
    28081 ttacgactat gctgttgtaa atgatgaagt gccgctagca gttgaacgaa tcaaaaacat
    28141 tattgccagt gaacattttc gagtagatcg cgtaatcggt aaatatatta aaatgttaaa
    28201 ggagatgtag tcttatgatg ttaaaacctt caattgactc actattagat cgtgtaaatt
    28261 caaaatattc tctagtgatt ttagcaagta aacgcgcgca tgaattggat gcaagtgcac
    28321 agcctactct agattctttt gattcagtaa aaagcgtcgg tcaagcttta gaagaaatcg
    28381 atgcaggaaa tgtagtcaat gatccacatc ctgaattaaa acgtgaacgt ttgaagatgg
    28441 aagaagagga acgtcaagca caaaaagagc gtgaacaaca cgaattggaa tcacgtatcc
    28501 gtgaagagca aaaaatgtaa taaagaaaaa tagagcgaac atctaaaaag aaaagcaaac
    28561 ccagctgttt ccttttcaaa cattcgccac ttattgtctg gtagaaaagg ctgtgtctga
    28621 actttttgac acagttcttt tttttcttat ctgctgttaa ttttttgtta ggatttggca
    28681 gaagataaga aaaatccatc gatctctagt aaaataggca aggaactttt tgtcgcttga
    28741 taagaaaaga caaaaaaagg aggaaacgaa ccatgacatt aacagctgaa gtcattgtgg
    28801 acgtacctac tatgcagacc gatcagccat tcacttattt ggttccctct gaaatggaaa
    28861 cagctttgca agtcgggatg cgagtagaag tcccttttgg taatggcaat cgtcatgtcc
    28921 aaggatttgt tatggctatc caaaaatcag aagaatcagc taatccatct ttgaaggcag
    28981 ttattcgttt gctagacctt gctccggtgg tcaatgaaga attactttca ttagctgatt
    29041 atatgaaaaa aattacttac gcattcaaaa tcacttgtct acaaacgatg cttccgagtg
    29101 tgatgaaagc agaatatgat aaattgatct atcctttggc agacacacca gaagttcagg
    29161 tattgtttga tcagcgagaa gtgatttcct ggaaggaagc agaagaagaa ggcagccttt
    29221 ctcaattgat tcgctggcgc caagagcaat tagtagatat caaatatgaa gtccatacac
    29281 gaaataaagt aaaaacgatt cgtttggtcc gttctttgtt aactgaaaag caaatcgaag
    29341 aagaatgggc aaaattacgg caaaatgcca agaaacaaaa agaacttctt ttgtgtttat
    29401 ctgaactgag ccaagaagaa ccaattgctt atttcaaaaa taaaggaatc agtactgctg
    29461 tcttgaatca aggaaaagaa aagggctggc tggagtttat agaatcagaa cgttatcgcg
    29521 acccttataa agaccgagta tttgaccaaa cgacggcatt ggaactgaat gcagaacaaa
    29581 aaaatgctgt cgaacaaatc atcacagcag gtcagcagca aaaagatcag gtctttttgc
    29641 tggagggaat cactggcagc gggaaaacag aagtatatct tcaggcaatc gctgatgttt
    29701 tgtcagaaaa taaaacggct attatgttag tgcctgaaat cgcattgact ccgcaaatgg
    29761 tcgagcgatt caaaggacgc ttcggagaat cagttgcggt cttacatagc ggactttccc
    29821 aaggtgaaaa atatgatgaa tggcgcaaga ttgagcggga agaagcgcaa gtagtagtag
    29881 gcgcacgatc tgctattttt gccccgctga aaaatatcgg gctgatcatt atcgatgaag
    29941 aacatgaatc aagttacaaa caagatgaga caccgcgtta tcatgcgaga gatctagcaa
    30001 tttggcgcag taaatatcat cattgcccaa tagttctagg aagcgcgacg ccctctttag
    30061 aatcaagagc acgagctcaa aaaggcgttt atcagttatt gcagttaaac caccgagcca
    30121 aagcagctgc acagcttcca gctattgaga tcgtagatat gcgtgaagag tttcagaatc
    30181 atcggacctc tactttttct gctaatttgc aggaaaaaat acaaaatcga ttagacaaaa
    30241 aagaacaaac tgtcctactg ctcaatcgtc gaggatattc gtcttttgtg atgtgtaggg
    30301 actgtggatt tgttcttcca tgtcctaatt gcgatatctc tcttacactg catatggata
    30361 cacgttcaat gcgctgccat tattgcggac atgaagaacc tattcccaat cgctgtccta
    30421 attgtggcgg caataaaatc cgctactatg gaacaggtac tcaaaaagta gaagaggaac
    30481 tccgagaact ttatccgcaa gctaggattt tgcgtatgga tgtagatacc actcgaagaa
    30541 aaggggcaca cgaacagatt ttacaaaaat tcggtgcaaa agaagcagat atattattag
    30601 ggacacaaat gattgctaaa ggtttggact ttccagaagt gacattagtt ggggtgttga
    30661 atgctgatac ctccctgaat ttaccggatt ttcgttctag tgagcataca ttccaattgc
    30721 ttacccaagt ttcaggacga gcagggcgag cggaaaaagc aggcgaagtc gtgatccaaa
    30781 cattcaatcc tcaacattac gccatagaat tggctaaaaa acaaaattat gagcagtttt
    30841 atcagcagga aatgcatgta cggcatcgtg gaggctatcc tccttattac tttactgtga
    30901 aaataaccgc cagccatcct gaagaacaag tagcggcaaa gaaaatcttt cagattgcca
    30961 atcagctaaa agaagtgtta agccctcaaa gcttgctatt agggccaacg cccagcatga
    31021 ttttgagagt gaaaaaccga tattattatc aactaatcat caaatataaa catgaaccga
    31081 atcttcctca tgttttggat gaaattttga atggaagcca gaaagaacag cgacaaggtc
    31141 tttttgtggc aattgacaac gaaccattaa actttattta agaaagggcc aaattatgcg
    31201 ctatcctata ttgatccacc ctaatgataa attaaaaaga actgctcagc caatcgatgt
    31261 aatcacggac gagacaatcg ctttattaga caatttatat gagacaatga ttgcgaatga
    31321 cggaataggg atcgctgctc ctcaagtagg acaaaacaag agaattgctg tgatcgaagt
    31381 agatgaaggc gagaaatttg aactgattaa cccagaaatc atcgaagcaa aaggtgaaag
    31441 ccttgacgta gaaggttgtc tcagtattcc gcatgtctat ggaacggtca agcgagcaga
    31501 tgaagtgacc gtgcgttatt atgatcgaga cggagaagag atagaagtga cggcttttgg
    31561 ctatttagcc cgtgccttcc agcatgaaat cgatcactta gacggtatct tgttcattga
    31621 gaaaatgata cagcagatcc cggaagaaga acttgaagaa tatatggagg aacatcttga
    31681 tgactaagct agtatttatg ggcacacctg ctttttctgt gccgattctt gaagggctga
    31741 tagaatcagg ttacgagatc caggcagtgg taacacagcc cgaccgtcca gttgggcgga
    31801 aacgagtaat tacgccgaca ccggtaaaag aagcggctct gaagcacggt atccgtgtgc
    31861 tgcagccaga gaaaatctcc ggttcgccag aaatggaaga aatcattgaa ttggtgcctg
    31921 atgtgatcgt cactgcggca tttggccaat tcttgcctga aaagttattg caagtaccaa
    31981 aattaggggc aatcaatgtc catgcttctt tacttcctaa atatcgggga ggtgcgcctg
    32041 ttcattatgc catcatgaat ggggagaaag aaactggtgt aacgatcatg gaaatgatca
    32101 aaaaaatgga tgcaggcgga atctatgcgc aagaaagcat accaatcact aaacaagatg
    32161 atgtagggac gatgtttgaa aagcttagcc ttttaggaag aaagctattg ctagaaacat
    32221 tgcccaatat tttggatgga caaaaaccag tacctcaaga cgagtcagaa gcaacttttt
    32281 cgccaaacat cacacgggaa caagaagcaa tcgattggca taaaactgca gaagaaattg
    32341 acaaccaagt acgcggaatg cgtccttggc caattgcatt cacgacctat gagggcatac
    32401 gctggaaatt attatcggtt gaagtattgg cagaaactac agacaaagca cctggtacga
    32461 tcatccggaa agacaaaaaa aatctatgga ttgcttgcgg taaacagacc gtcttagcca
    32521 tcaatgaatt acagccagct ggtaaaggaa aacaggccgt acatgatttc cttaacggaa
    32581 gcggtcagca agttcagatt ggtcagcagg tgaaataatg aaaaaaatcc ctaaaaaaat
    32641 gaaaaaatca gtacgatata tggcattact gacattagag cgagtgaaca agggtggcgc
    32701 ctactcgaat cttttgttga atgagatgat caaacaaagc gagctaaatc aaaaagatgt
    32761 gggtttattt acagaattga tctatggtac gattagccat cagcgactat tggaatttta
    32821 cgttgcacca ttgatcgcta aagcaaaaaa agtggatgac tgggtcaaga cgcttcttta
    32881 tctttctgta taccaattag aatttttaga taaagtccct gcacatgcta ttttaaacga
    32941 ggcggtcgaa atcgcaaaag taaaaggaaa tcctgggaca gggaaatttg taaatggtgt
    33001 cttgaggaat tatcagcgtc aaggagcacc agatctgcaa ggcattgctg atcctatcga
    33061 aagactttct gtcaaaatca gcctgcctct atggatgact aaacgactgg tggatcaaat
    33121 cggatacgaa gaaactgaaa agctcggttt atcgctatat cagcctagcc atgctagtgc
    33181 ccgagtagat acacgccgac tttccagaga tcaggccatc actgttttgc aagaagaaga
    33241 gatcacagct gaaaaaagcc aagtcagtcc atacggtata gtagcgaaaa aagggcattt
    33301 agcttctagc tcattgttcc acgatggcgt catgacgatc caagatgaaa gttcgatgct
    33361 tgtagcgccg tctatgcaaa tcgagcctga acatcatgtc ttagatgcct gtgcagcacc
    33421 cggaggtaag acgacgcata ttgcttcttt tttagatccg tcatgcggtg gagaagtggt
    33481 cgctttagat gtacacgaac acaaagtcaa actcattgaa gataatgcag cacgtctagg
    33541 tgtctcttct gctgtctacg ctcaaaagat ggatgctaga gaagtcagta aacagttcga
    33601 agcagagcag tttgatcgga ttttagtaga cgcgccttgt tcaggtcttg ggctgcttcg
    33661 gcgaaaacca gatattcgtt ataaaaaaca gccggatgaa ttagcgaatt taccaaaaat
    33721 ccaattggaa attttagaaa gctgcgcacc aactttaaag tcttccggta ttctgactta
    33781 tagcacttgt acgatcttaa aagaagaaaa ccaagacgtt gtttctgctt tcttggaaag
    33841 acaccctgat tttgagagga ttgatgtttt gaccaatcct atgctacaat catcaatcga
    33901 agagaaaatg ttgactttgt atccgcatca gttttacaca gatggatttt tcatttgttg
    33961 tttgcgcaaa aagtaatgag gtgaaaaaat gcagattgaa tatcaatcag atgtaggaag
    34021 acgacgtaac acaaatcaag actatgccag tgtatttacc agccgttcag gtctcaagct
    34081 tgctgtatta gcagacggga tgggtggtca tcgtgccgga gacattgcca gtcagatggc
    34141 ggtaacgaat ctaggcgaag cttgggaaaa acaagaagct gttgacgatg aaaaaatcgc
    34201 ccaatggttc attcaatcga ttcaagaaga aaatatgctg atttatcagc gtggacaaga
    34261 acagccggaa tataacggta tgggaacaac aatcgtagcg gccgctctgt cagatgactg
    34321 gttcacgatt gccaatgttg gggatagcag agcttatttg attcgtgaag ataaaatcat
    34381 gcaattgacg gaggatcatt ctttagtcaa tgaactagtc aaatcaggag aaatcagcga
    34441 agaaatggca gtgaaccatc caaggaaaaa tattttaaca cgttctgtcg gcatgcctgg
    34501 aacagtcgaa gtagatgttt ctactcatct ttggcaacta aaagatcgac tgctgttatg
    34561 ttcagatggc ttgacgaaca tgctgtctga agaagaaata ggaacgatca tcaatcaaga
    34621 aggcccattg tctcataaag taactgagct gattgatcgt gccaatgaag caggcggagc
    34681 ggataatatc accgttcttc ttatcgaata taaggaggac agtgtatgat cgagttgggc
    34741 aaaaaattaa atggccgtta tcaaatcact ggaaatatcg gtagcggtgg tatggcaaat
    34801 gtatttttgg cgcacgattt aatcttggat cgtgatgtag cagttaaagt cttacgattt
    34861 gactttcaaa atgaccagac tgcgattcga cgatttcaga gagaagcttt agcagcaaca
    34921 gaactcgttc atccaaacat tgttagtgtt tacgatgttg gtgaagaaga caacatgcag
    34981 tatctggtga tggaatacgt caaaggaatg gacttgaaac gatatatcca aacacattat
    35041 cctgttcctt atgaaacagc agtaaatatt atgcagcaga tcctttctgc tatttcttta
    35101 gctcataacc atcaaatcat ccaccgagat ttgaaacccc aaaacgtact gatcgataat
    35161 gaaggtgttg taaaaatcac ggatttcggg attgctatcg ctttatctga aacatcgatc
    35221 acgcagacga atacgatgct aggatctgtt cattatctgt cccctgagca ggccagagga
    35281 agtatggcaa cgaagcagtc agatatttat gctttaggga tcatccttta tgagatgttg
    35341 acgggtagcg taccgtttga tggtgaatct gctgtaacaa ttgctttaaa acattttcaa
    35401 gatgatcttc catctataaa agcacttgat ccaaatgtgc cacaagcact ggaaaacgtg
    35461 attttacggg caacggctaa agaacctgca gaccgttata agtcagccga ggaaatgtct
    35521 gatgatcttt ctacagtatt atcaccagct cgtgcaaacg aagaaaaatg gcagcctcat
    35581 gtgatggata atgaaacaaa agttatcaca ccccttacgg aagatgcacc aatgcctgat
    35641 tcattcaaat ctatgcctct gccaaaagac aagccagaaa acgaaacctt accagaggag
    35701 gaagaagttc tgcctgatcc taaaaagaaa ggacagaaaa aatggtggct gatcctatta
    35761 gctattcttg ctgttttagg aatcggaaca gctgtattct ttgcttctgg cgggcgagga
    35821 gaagttgttg ttcctgatgt ttctgatctt tctgaagctt ctgctagaga aacactcgca
    35881 aaagcgaaat tagaagtagc aacaaaaaca gaagaaattg cagatgacaa aatcgaagaa
    35941 ggtaatgtag tgaagacaga cccggcagcg ggaacgacag tcaagcaaaa acgcgaagtc
    36001 actctgtata ttagtagcgg cacgaaaaaa atcaaattag atgattacag tggtaaaagt
    36061 tatgaagatg ccgaagcaag tttgaaagaa ttagggtttt ctgctgactt gattcaaaaa
    36121 gaagaggaat tcagttcaga ggtagaaagc ggaatgatca tttcgcaatc tccatcagaa
    36181 gatacagaag tcgatcctaa aacagacacg attactttca cagtcagcaa aggaccagaa
    36241 acagtgactt tgagtagtca tgtaggagaa aactacgaaa ctgttcgtaa ttggcttgtt
    36301 acacaaggat tcaatatcaa taatattagt gctacttatg actatagcga cactgtacca
    36361 tcaggttcga tcatcagtca ggatccagcc tcgggtgaag ttgtagcaga agaaacttac
    36421 atcaattttg tcgtaagcca aggaacagag cctaaattga atgatatctc cggctataca
    36481 aaaagcgaag cacaaagtta tttagctagt gtcggtgcag aatatatcgg gcatgagact
    36541 tccgaatatt caaacacggt ggataaagat aaagtgattc gtacagtacc aggggcagga
    36601 acgacaatta ccaaaggaat ggttgtgaac gtaatttact ctaaaggacc agatccagcg
    36661 tcttctagtt ctgaaaaaga ctcttcagac agttctagca gctcaagtag ctccagtagc
    36721 acaagcaact cttcaaaaga agaatcttcc agctccacaa gttcatcagc tagcacctca
    36781 gaaagttcaa aataagtgct gaataaaata tatcagaagg gaatgcgaca ttgatttgtt
    36841 gcattctctt ttttgtgttt ctatctcttt tgatcaattt tcaagccata tactttgaga
    36901 agtttgcatg gaataacacc tactttcctc ttcgtatggt aaaataaaca aaaacggagg
    36961 tggcacttat caaaggacaa atcagaaaag caatcagcgg tttttactat gtatacgcaa
    37021 acggagagac ctatcaaaca agaggaagag gaaatttccg gaatcggaaa atcacgccgc
    37081 ttgtcggaga tcaggtgatc tttgagagtg aaaatcaaac agacggctat cttctggaaa
    37141 tcttgccgag aaaaaatcaa ttagttcgcc caccagtcac aaatgttgat cttggaatca
    37201 ttgtcacaag tatcgtagag cctgcatttt cttataatct acttgaccgc tttctagtta
    37261 ccttggaata cgagtcgatc gaaccgatta tttttttgac aaagaccgac ttgtcagacg
    37321 acccagaaaa aatcgaagag atcaagcaaa cctatactaa aataggctat ccggtgattg
    37381 tacccaatca tacgggtgat acgacagaac tgatccgtta cttcccagaa cggctatcgg
    37441 tctttatggg tcagtctgga gcaggaaaat cgacgctact gaatcaaata tcaccggaac
    37501 tgaatttagc aacaggagag atttctgatg cacttggaag aggacggcat acaacacgtc
    37561 atgtggaact gattcctatc tatggcgggt tagtagcaga tacaccagga tttagctcga
    37621 ttgacttttt gacaattgaa gcaggagaac tgccgagaca atttcctgaa tttgtagaag
    37681 cttctgtcca ttgcaaattt agagagtgca tgcatgctaa agaacctggc tgcgaagtaa
    37741 aacatagagt agaaacaggt ggtatcgcac agacacgtta cgacaattat ttgcaattct
    37801 tacaagaaat cgaaaaaaga aaaccaatgt atgcaaaaaa agaaggtaaa cgaaaatagg
    37861 aggaaacaag aatgaagata gcaccatcca ttttgagtgc agattttgcc aatttacaaa
    37921 gagacattga gttagtggaa aaaggaggcg cagattacat ccacgtagat gtaatggatg
    37981 gccaatttgt cccaaatatc acattagggc caaatattgt tcaggcaatc cgtcctgtta
    38041 ctaaattacc gttagacgtc catctgatga tcgttgatcc agaaaactac attccagcat
    38101 ttgcaaaagc tggagcagat atcattactg tccacgtcga agcaactcct catattcatc
    38161 gggcacttca aatgacaaaa agcttaggag ttaaagctgg agtagttatc aatccaggaa
    38221 caccagtctc catgatcaaa catgttttgc ctttggctga tcaagtacta gtcatgactg
    38281 tcaatcctgg gttcggcgga caaagcttta ttgaagaaac agtagaaaaa attacggaac
    38341 tcgctgatct acgtagagag aacaattgga cttatgcaat cgaagtagat ggcggaatcg
    38401 ttccagaaac agcaaaaatc tgtaaagatg caggggcgga tgtcttcgtt gcaggatcat
    38461 atatctatgg agccgaaaat ccagtcggac aaatcgaacg attaaaagag gcattagact
    38521 aaatgaaaat tttattagct gctggaggta atccgcaaaa ctggccgcag tctctgctgt
    38581 ccaaatacga tgcctatgtc gggatagacc gtggtgcgct gtacctgctt caagcaggct
    38641 acccagtaga tctggcagtg ggtgattttg attcattgtc gaacgaagag cagaaggaag
    38701 tatttgcaaa agccaaagag tatacccgtt cccctgcaga aaaagacgat acagatacac
    38761 agttaggtat cttaaaaaca tttgaacgtt acccgcaagc ggaagtcact ttgattggag
    38821 ctacgggcgg aagattggat catcttttag ccaatctctg gttaggtatg gaacctcgct
    38881 tcaaaccctt tgcccatcag cttattatca gagattgtca aaattatttg tcttattatt
    38941 tgcctggaga gcatatagta agacagatac cagatatgaa gtatttagct tattgctgct
    39001 tgactcccgt ctcgaatctt acattaaaag gcagcaagta tgtattggaa aataaagaag
    39061 tagaatatcc gacatcttat gcaagtaacg aatttctttc agataccgca gaattttctt
    39121 tttcagatgg tatgattgca gttattcaaa gcaaagattg atccataaac aaataaaaaa
    39181 atttgtcttt caggctaaaa atgacagaat ctattatttg ctaaaaaaaa gcttaagagg
    39241 agcaacttac cttttgtttc acggcattta gtgataaaat tgaacacaag agtctaatta
    39301 attcgaggtg tctttgtgaa gaagttcaat cctaataaaa atattattat taccttggtt
    39361 attgttatca tcgtggtgac gatactaagt gtgaccgctg cgcagcgagc gaatgaagga
    39421 aagcccaatt tcttccaatc catcgttaat gacagtgttg caatggttga taaaacaatc
    39481 tctgccccag tacggtgggt acgaaatgga gtagattctg tccataatct tttttcaact
    39541 tatgccgaaa atgagcggct aaaagaaaaa atcgatagct atgatgacgt ttcacaacaa
    39601 aacaagaatt acgagagaga aatcgaagcg ttgaaaaaag aacttgagtt gaatcagacg
    39661 ctgactagtt acgaaaaagt aacggcaaat gtcattactc gttcgcctga cagttggcag
    39721 gacatgctga tcgtagacaa gggttctaaa gacggtatcg aagcaaatat ggcagtcatg
    39781 tcgcaaaaag gattgattgg ccgagtgatc gaggtcaata cggcttcgtc taaaatcgaa
    39841 ttactgtcat cctctaatga aagctccaat cattttccag tacgggtatc ttcggctaat
    39901 ggcgaagcgt ttggtttgct taaaaactat gatgaaaagc tccatgcctt agtggtgacc
    39961 caattaactg gtgatacgga tatcaaagaa ggggatgttg tccagacatc cggtcttgga
    40021 gggaattctc cagctaactt gccgatcggt acggttatta aaacgaaacc agatagttat
    40081 gggctggatc gggaagttta tgtgaaacct tatgcagaaa tgtatgacgt gtcagttgtg
    40141 acgattgtcc aacggctagc ggaggattag tccatgttga agaaagaaac aatgaagtac
    40201 tatctgccaa tcgttttgtt ctttttgatg ttgatagatg gtcatttaac aagaatgcta
    40261 ggggagtggt cgaaaggcac ctatatgtca aatgcccact ttctgatatt ggcattatta
    40321 tgttgcagta tggcgtttga aaaacgttat ttactgatta ccacgattgt tctcggggct
    40381 atctatgacg cttactatat tggcgttatc ggtatctatg cagtagctct ccctttaatt
    40441 gtatggttga tgtatgtaat gaaagacgtt atccatgtca acatctttac tgaatttttc
    40501 agtatgatca tctttgtcac gggttatgaa ttgtttacga tggtggtcca gttgattttt
    40561 aaattagcag tagtaaataa cacgtatttt attacaaggt ttttaggacc tacactgctg
    40621 ttgaacatga ttatatttgt attattcatt tttcccttta agaaattatt cagtgatgaa
    40681 taatttcttt ttttattttt aggtcgaaag cgaaaaagaa tcgttgttat cttaagaaat
    40741 gctagactta acgcggcttt ttcatgatca ttttctgaaa cgaacagttt tgtcattttt
    40801 aaaagttgtt ttgaaacatt tttgtaacat aactattata tcgttgacac actgctatgg
    40861 tacaattttt atatcgttaa gaaagactta aatatattta gatatttatt aaattaagcc
    40921 agtcggagga atgaagagtg aaaaagagtt taatatcagc agtaatggta tgttcaatga
    40981 ccttgactgc cgtagcatca ccgatcgctg ccgcggcgga cgattttgat tctcagatac
    41041 aacagcaaga tcaaaagatt gcagacttga aaaatcaaca agcagatgca caatcacaaa
    41101 tcgatgcctt agaaagccaa gtttctgaaa tcaacacaca agcacaagac ctattagcaa
    41161 aacaagatac attgcgtcaa gaatctgcac aattagtaaa agacattgca gatttacaag
    41221 aacgtattga aaaacgtgaa gatacaatcc aaaaacaagc acgcgaagca caagtaagca
    41281 acacaagctc aaactacatc gatgctgtat tgaatgctga ttcattagca gatgctattg
    41341 gacgcgttca agcaatgaca acgatggtaa aagcaaacaa cgacttgatg gaacaacaaa
    41401 aacaagataa aaaagctgta gaagacaaaa aagctgaaaa cgatgctaaa ctaaaagaat
    41461 tagctgaaaa ccaagctgct ttggaatctc aaaaaggcga tcttttatct aaacaagctg
    41521 atttgaacgt actgaaaact tcattagctg ctgaacaagc aactgctgaa gacaagaaag
    41581 ctgacttgaa ccgtcaaaaa gcagaagctg aagcagagca agctcgtatt cgtgaacaac
    41641 aacgtctagc agaacaagct cgtcaacaag ctgcacaaga aaaagctgaa aaagaagcac
    41701 gcgaacaagc agaggctgaa gcacaagcta ctcaagcttc atctactgca caaagctcag
    41761 caacagaaga atcatcagct acacaatctt caatgactga agaatcatca tcagctacac
    41821 aatcttcagc aacagaagaa tcaacaacac ctgaatcttc aacagaagaa
//
LOCUS       DAFBSV010000011        41393 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.011, whole genome shotgun sequence.
ACCESSION   DAFBSV010000011 DAFBSV010000000
VERSION     DAFBSV010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41393
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.011"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            476..718
                     /locus_tag="LLB18_000634"
     CDS             476..718
                     /locus_tag="LLB18_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HBK5243660.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITAHKVK"
     gene            715..1185
                     /locus_tag="LLB18_000635"
     CDS             715..1185
                     /locus_tag="LLB18_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBK5243661.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWRKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYETYGKIYEEIIPSTSYIPIKDIILHFEKYDYRFHWNSDNSVIEIWIPIQD"
     gene            1313..2527
                     /locus_tag="LLB18_000636"
     CDS             1313..2527
                     /locus_tag="LLB18_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBK5243662.1"
                     /translation="MNDKNFIEELRQKREEYGVTQTRLAVACGISREYYNRIEKGKQP
                     LNDELREIIEKQIERFNPQEPLFLLIDYFRVRFPTTDALAIIRDVLQLKSNYMLYEDY
                     GKYGYESKYVLGDINIMCSMQEHLGVLLELKGKGCRQMECYLLAQERSWYDFMLDCMT
                     AGGVMKRLDLAINDKAGILDIPKLKEKYKAGECMSYFRMQKDYSGTEKCGSDLPKNTG
                     ETLYLGSTSSELYMCAYQKNYEQYVKNGTEIEDTEIKNRFEIRMKNERAYYAVVDLLT
                     YRDAERTAFSIINHYVRFVDREDDKPKSQWITNDDWAWFVGENREPIRLTTKPEPYTL
                     QKALHWLQRQVAPTIKMVQALDRENRTTILKDMIEQAELKDKHKHLLQLEKSTIEERI
                     DTAVPQENDGIF"
     gene            3516..3725
                     /locus_tag="LLB18_000637"
     CDS             3516..3725
                     /locus_tag="LLB18_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
                     /protein_id="HBK5243663.1"
                     /translation="MNCLERFYRKGVCVIDNAVKTIQKKNGKCGIGNRGKTKIVVKEH
                     FSEKGKTMEELLTDVMLEKAKQTIA"
     gene            3837..5450
                     /locus_tag="LLB18_000638"
     CDS             3837..5450
                     /locus_tag="LLB18_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBK5243664.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFDRPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIIEKIFSLAYQGYGSAKITKQLRAEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     GTNKTNKTPYSYYACSYYGQFGKGNCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASTLKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITSLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEATTNEDNERIQEIEIYYRFIGRVE"
     gene            5485..6696
                     /locus_tag="LLB18_000639"
                     /pseudo
     CDS             5485..6696
                     /locus_tag="LLB18_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            6719..7645
                     /gene="glsA"
                     /locus_tag="LLB18_000640"
     CDS             6719..7645
                     /gene="glsA"
                     /locus_tag="LLB18_000640"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBK5243665.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            7853..9313
                     /locus_tag="LLB18_000641"
     CDS             7853..9313
                     /locus_tag="LLB18_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243666.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIREIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            9534..11297
                     /locus_tag="LLB18_000642"
     CDS             9534..11297
                     /locus_tag="LLB18_000642"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBK5243667.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            11381..11839
                     /locus_tag="LLB18_000643"
     CDS             11381..11839
                     /locus_tag="LLB18_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HBK5243668.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            11948..12631
                     /locus_tag="LLB18_000644"
     CDS             11948..12631
                     /locus_tag="LLB18_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBK5243669.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            12778..13392
                     /locus_tag="LLB18_000645"
     CDS             12778..13392
                     /locus_tag="LLB18_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBK5243670.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            13408..13614
                     /locus_tag="LLB18_000646"
     CDS             13408..13614
                     /locus_tag="LLB18_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243671.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            14155..15285
                     /locus_tag="LLB18_000647"
     CDS             14155..15285
                     /locus_tag="LLB18_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBK5243672.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            15377..16132
                     /locus_tag="LLB18_000648"
     CDS             15377..16132
                     /locus_tag="LLB18_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBK5243673.1"
                     /translation="MKVSQKIILSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEP
                     KSIPTTLNVALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGM
                     NKINAAYSYGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSL
                     DLDGVYINKGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFK
                     LPKAVGKLLGSIQTNLPESVLLDCGMDFLKDIC"
     gene            16190..18229
                     /locus_tag="LLB18_000649"
     CDS             16190..18229
                     /locus_tag="LLB18_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HBK5243674.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSYQATRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(18338..19489)
                     /locus_tag="LLB18_000650"
     CDS             complement(18338..19489)
                     /locus_tag="LLB18_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBK5243675.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(19643..20173)
                     /locus_tag="LLB18_000651"
     CDS             complement(19643..20173)
                     /locus_tag="LLB18_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBK5243676.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(20272..20622)
                     /locus_tag="LLB18_000652"
     CDS             complement(20272..20622)
                     /locus_tag="LLB18_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HBK5243677.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(20779..22308)
                     /gene="ahpF"
                     /locus_tag="LLB18_000653"
     CDS             complement(20779..22308)
                     /gene="ahpF"
                     /locus_tag="LLB18_000653"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HBK5243678.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(22318..22881)
                     /gene="ahpC"
                     /locus_tag="LLB18_000654"
     CDS             complement(22318..22881)
                     /gene="ahpC"
                     /locus_tag="LLB18_000654"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBK5243679.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(23025..23687)
                     /locus_tag="LLB18_000655"
     CDS             complement(23025..23687)
                     /locus_tag="LLB18_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK5243680.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            23871..25517
                     /locus_tag="LLB18_000656"
     CDS             23871..25517
                     /locus_tag="LLB18_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBK5243681.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            25508..26590
                     /gene="uxuA"
                     /locus_tag="LLB18_000657"
     CDS             25508..26590
                     /gene="uxuA"
                     /locus_tag="LLB18_000657"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBK5243682.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(26698..28251)
                     /locus_tag="LLB18_000658"
                     /pseudo
     CDS             complement(26698..28251)
                     /locus_tag="LLB18_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            28399..29540
                     /locus_tag="LLB18_000659"
                     /pseudo
     CDS             28399..29540
                     /locus_tag="LLB18_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(29666..30745)
                     /locus_tag="LLB18_000660"
     CDS             complement(29666..30745)
                     /locus_tag="LLB18_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBK5243683.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(30848..31288)
                     /locus_tag="LLB18_000661"
     CDS             complement(30848..31288)
                     /locus_tag="LLB18_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK5243684.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(31345..31755)
                     /locus_tag="LLB18_000662"
     CDS             complement(31345..31755)
                     /locus_tag="LLB18_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBK5243685.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(31935..32369)
                     /locus_tag="LLB18_000663"
     CDS             complement(31935..32369)
                     /locus_tag="LLB18_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBK5243686.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(32469..33317)
                     /locus_tag="LLB18_000664"
     CDS             complement(32469..33317)
                     /locus_tag="LLB18_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBK5243687.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            33706..35472
                     /locus_tag="LLB18_000665"
     CDS             33706..35472
                     /locus_tag="LLB18_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBK5243688.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            35574..36833
                     /locus_tag="LLB18_000666"
     CDS             35574..36833
                     /locus_tag="LLB18_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBK5243689.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            36980..38281
                     /locus_tag="LLB18_000667"
     CDS             36980..38281
                     /locus_tag="LLB18_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK5243690.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            38284..39135
                     /locus_tag="LLB18_000668"
     CDS             38284..39135
                     /locus_tag="LLB18_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK5243691.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            39148..39963
                     /locus_tag="LLB18_000669"
     CDS             39148..39963
                     /locus_tag="LLB18_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HBK5243692.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            40114..41280
                     /locus_tag="LLB18_000670"
     CDS             40114..41280
                     /locus_tag="LLB18_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBK5243693.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
BASE COUNT        14049 a         7170 c         8044 g        12130 t
ORIGIN      
        1 tttttccgcc atgcttgcaa gggggcggtt cgcttcggcg gttcggcgag cttgcgagcc
       61 gttcaaagcc cccgttatct aacaaggggg gcacaaaaaa caagaaacac tatacactaa
      121 caagcggaaa acgctgtatt tataaggcaa aaccccattt ttacagtagt gatataaatt
      181 gtacctatat cactatgaaa attgaatagt aaatatgaga aagacagttg atttcaaaaa
      241 ataagaaatt gattgtcgtt ttcttttgca gaaatttaag tgcaggcaat tatggtagtt
      301 gtcgtaattg ctgtcagctc agtgtttatc actgatggtg tgaaagattt acggttggag
      361 atgttcaata agattattgg tgcttaatta tttttattgt agtgctgata tgagaatgtt
      421 ataattgggg tataaaacat acaaataaat ttgctgaaaa atgaggtatc aaaatatgga
      481 aaatgaatta ctggaaaact taggaagact tcacacaact gaacttggcg ttattagaat
      541 taaaaagaac ttatctttga atgtagaaaa tgtaattgaa tggtgcaaag aaaaaattag
      601 cctttctaat gcggaaatca caagaaaagg aaaaaactgg tatataacga ttgataattg
      661 tattataacg gtaaatgcgt acagttatac cgttatcact gctcacaagg taaaatgata
      721 aatttttcta taaaggaatt aaacgcattt gcagttattg ggcaggaagt agaactgact
      781 aattatcaaa aaaagaatat tcagattagt acacagtttt ggagaaagtt taacagtagt
      841 ttgaaaaaag cgtatctttc acaatcagga aattgggtaa aatatgcttt tatggaaaga
      901 agaaatggaa aactttatta tttctgttct attccccaaa gaaccattac cccagagggc
      961 tttctgtata aagaaatacc gtcttataaa tatttggttg tggagcatat tggtgctatg
     1021 gataaaatat atgaaactta tggcaagatt tatgaagaaa ttattcctag tacatcgtat
     1081 attcctataa aagatattat cctacacttt gaaaaatacg attatcgttt tcattggaat
     1141 agtgataatt cagttattga aatttggata cctattcaag attagaagca attttatatc
     1201 catacacaca aagcagttag tcttaggatt gactgctttt tctatacaga tttttaatga
     1261 caggcaatta tcaattatgg tagttgcctt ttttgattgg aggaattgaa gaatgaatga
     1321 taaaaacttt attgaagaac taagacaaaa gcgtgaggaa tacggagtaa cacaaacaag
     1381 gcttgctgtt gcctgtggta tcagccgtga atattacaac cgcattgaaa aaggaaaaca
     1441 gccattgaat gacgaattaa gagaaatcat agaaaaacag attgagcgtt tcaatccgca
     1501 agaaccacta ttcttattga ttgattactt tcgtgtccgc tttcctacta cggacgcatt
     1561 ggcgattatc cgtgatgtat tacaactgaa atctaattac atgctttatg aagattatgg
     1621 aaaatacgga tatgaaagca aatatgtact tggcgacatc aatatcatgt gttccatgca
     1681 ggagcattta ggtgttttat tggaactgaa aggcaaaggc tgtcggcaaa tggaatgtta
     1741 tctgctggca caggaacgct catggtatga cttcatgctg gattgtatga cggctggtgg
     1801 tgtgatgaaa cggcttgatt tggctatcaa tgataaagca ggaatattgg atattccaaa
     1861 gttaaaggaa aaatacaagg ctggcgaatg tatgtcctac ttccgtatgc agaaagatta
     1921 cagcggtaca gaaaaatgcg gtagcgattt accaaagaat acaggagaaa ccttatatct
     1981 cggttcaaca agtagcgaat tatatatgtg tgcttatcag aaaaattatg agcagtatgt
     2041 caagaatggc acagaaattg aagatacgga gattaagaac cgttttgaaa tacgcatgaa
     2101 gaacgaacga gcctattatg cggttgtaga tttactgacc tatcgggacg ctgaacgcac
     2161 cgctttttct atcatcaatc attatgtccg ctttgttgac agagaggacg acaagccaaa
     2221 aagtcaatgg ataacaaatg atgattgggc atggtttgta ggggaaaaca gagagccgat
     2281 acgcttaacc acaaagccag agccttacac tttacaaaaa gcgttgcatt ggctacaaag
     2341 acaagtcgca ccaaccataa aaatggtaca ggcattagac agagaaaatc gtacaacgat
     2401 actgaaagat atgattgagc aggcagaact aaaagacaag cataaacatt tattacaatt
     2461 agagaaatca accatagaag aacgtataga taccgctgtt ccacaagaga atgacggtat
     2521 tttttaatgt aattgaaaaa tttcagattt agtcagcaaa gagctgtttt cattccctat
     2581 gtgaagtgaa agaagaaaaa taaatttttt attaaatctg caacaaaatg gctacttgcg
     2641 tacagatatg gtgcgagaaa aggaaatcta aacttttttt gaaaataggt cattaaatcg
     2701 gggcttgctg tccctatatg aagtgaaaga agaaaaaagt tttgaaaaaa tgacggaaat
     2761 tcgtgattag tggacagtct tctgtgaaaa gaggaaaaac atcatcattt tgtattcaaa
     2821 caggcattag cagttgagtg ttgatgtgaa aagatgaaaa tactttgttc tcaacttaac
     2881 aatttaaggt ttccgttccc tatatggtgc aaagaaaata tttcattcta ttgttggcag
     2941 taacggtatg gtttgggtag ttagggtgtg aaaaggaaaa tattcttttt tcatcatcaa
     3001 cttagcaaaa tgacattttc tatccctata tggtgcatga aaagaagtta aaatttttcc
     3061 atttaaactt agcaaatgga cgtttgctgt acagatagta gtgaaaaagg agaaaatcaa
     3121 ccgttgattg ccaaaatgaa ccgttccatt tgtactaata atggaaaaag ttttggattt
     3181 tggttacgtt tctcctcttt tccaacgcga tatataggaa agacgatttt tttctttcaa
     3241 tcgttctttg acaactgaat aaagctattc aatacgtttg acagacagct agccgttgaa
     3301 acaaatacgc cacgaccttt cccctgcaag agcgagcgaa aacctatttg tgttcttgta
     3361 aaagatttgt cctcttttat cgccatgacc tgtactgtca gataatgata ctcccgtaca
     3421 gccacagctt gagcattaag agcgtcgcac gcaatgggta cggctacata agaactatgc
     3481 agaggtggaa ctcctgtggg ctatgacaaa agccgttgaa ttgcttagaa agattttaca
     3541 gaaagggggt atgtgttatt gataatgctg taaaaacaat tcaaaagaaa aatggcaagt
     3601 gtggcattgg caacagagga aagacaaaga ttgtagtaaa agagcatttt tccgaaaagg
     3661 gcaaaacaat ggaagaactt ctaactgatg tcatgctgga aaaagcaaag cagacaatcg
     3721 cataaaatcg gtgcagttgt aagaaataga ttgaatgaca aaaagtaccc gtgttatact
     3781 ttacttgcaa gcaggtattg taaacacggg ttagttataa aggaggataa ctgacaatga
     3841 aacaacagat ttacaatact gcactttatc ttaggttaag ccgagatgat gaattacagg
     3901 gcgaaagttc cagcattacc acacagagaa gtatgttgcg tttatatgca aaagaacatc
     3961 atttgaatgt cattgatgaa tatattgatg acggctggtc gggaacaaat tttgacagac
     4021 cgagttttca aagaatgatt gaggatatag aggcaggaaa aatcaactgt gttgtaacga
     4081 aagacctttc ccgtcttggc agaaattata ttatgacagg acaatataca gaattgtatt
     4141 tccctagtca taatgtccgc tacatagcga ttgatgacgg tgtagacagc gaaaaaggcg
     4201 aaagtgagat tgcaccattt aagaacatca tcaatgaatg ggtggcaaga gatacaagcc
     4261 gtaaagtcaa atcagcattt aagacaaagt ttgcggaggg ggctcattac ggtgcttatg
     4321 ctccgttagg atataagaaa caccctgaca tcaaaggaaa actgttggtt gatgatgaaa
     4381 caaaatggat tattgaaaaa atcttttccc tagcctatca aggttacgga agtgcaaaaa
     4441 tcacaaagca gttaagagca gaaaaagttc cgacagcgtc atggctaaat tttacaagat
     4501 acggtacttt tgcacatatc tttgagggaa aacccgaaag taagcgttat gagtggacga
     4561 ttgctcatgt caaggcgata ttgaaaagtg aggtttatat cggaaacagt gttcacaata
     4621 tgcagtctac ggtatcgttc aagagcaaaa agaaagtgcg taagcccgaa agtgaatggt
     4681 ttcgagtaga aaacactcac gagccgatta ttgacaagga agtgttctat cgtgtgcagg
     4741 agcagataaa atcaagacgc agacagacaa aggaaaaggc aacgccgatt tttgcagggc
     4801 ttgtcaagtg tgcggattgt ggttggtcta tgagatttgg aacgaataag acaaataaaa
     4861 cgccttacag ttattatgct tgcagttact acgggcagtt tggcaaaggt aattgttcta
     4921 tgcactacat tcgttatgat gtgctgtatc aagccgtatt ggaacgcttg cagtattggg
     4981 ctaaggcagt acagcaggac gaagaaaagg tattgaacaa gatacagaaa gctggcaatg
     5041 cagagagaat acgggaaaag aagaaaaagg caagtacatt gaagaaagcc gagaacagac
     5101 aaaatgagat tgaccgttta tttgcgaaaa tgtatgaaga tagagcctgt gagaagataa
     5161 cagagcgaaa ttttgtgatg ttgtccagca agtaccaaaa agaacagata gaactggaac
     5221 agcagataac aagcctaaga gaagaactaa gtaaaatgga acaggatatg ataggtgctg
     5281 aaaagtggat tgagttaatc aaggaatatt ccgtaccaaa ggaactgaca gcaccattat
     5341 taaatgccat gatagaaaaa atcctcatac atgaagcaac aacgaatgag gataacgaaa
     5401 gaatacagga aattgagata tattaccgat ttattggaag agttgagtaa tcaacaagag
     5461 taatattttt aactaaggga aaccggcggt gtctatactt gggtcagtcg cacattggga
     5521 aaacgattcg gttttgccgc aatctttttc caatggtttg agataacagt tggctacttg
     5581 accatgctgt atttcttaac tggtgcatta tcctatgcaa cgggtattgg tgctatacaa
     5641 aacaataaat atctgaaatt ggcaatccta ttgattattt tctgggctat tttactctca
     5701 cagttaaaag gaaccaaata cacttcattg attgctcgga tcggttttgt agctggtatc
     5761 ttgttgccag cattagtctt gtttggctta gggatccatt atgtcgcttc aggcgctcca
     5821 ctacaaacga tactgtctat gaaaacattg attcctgatt tttcgaaatt gcctacgctg
     5881 gttgtttttg tttcctttat tttagcatat atgggcgtag aaacatctgc cagtcatgca
     5941 aatgaaatgg aaaaccctaa aaaggattat ccattagcaa tgtttgtatt ggttattctg
     6001 gcaatcattt tagatacttt tggcggattg accgtcgcta ctacagtacc tcaacatggt
     6061 ttgtctctta atacaggggt gattcaatcg ttagaattcc tattaagaca cattgatcca
     6121 aatcttgcat ggattgcgaa aattcttgcg attcttgttt gtttaggtgt catcggagaa
     6181 attgcttctt gggtaacctc tccttcaaaa gcacttcacg tagcagcaga agaaggatta
     6241 cttcctgaat attttgcaaa agaaaacaca cacggtgttc ctgctcattt gatgatcgca
     6301 aatgggatcg ttgcaacaat ctgggcagcc gtctttacat taagcggcgg ggggaataat
     6361 ctttcatttc ttgcagcgat gtcattgact gttgtaatct acctgatgtt gtactttatg
     6421 tttttcgcgg gctatttgaa gctggttttt aaagatgaca gtcttgaaag agcctatcag
     6481 gttccaggcg gaaaagttgt aaaagtaatc gttgcttgtt taggtctttt gacttcactt
     6541 tttgcttttt gtatctcatt tgttccacct gctagtatcg cagctggaca gcatgggatt
     6601 tatgaaacga ttctgattgt ttcttatctt atcgtcttag ttattccatt tacgatctac
     6661 gcatgccgtc ataaattcca gcatgcagaa aaataaaaaa tgaaagctgg ttattcaaat
     6721 ggaagtaaaa gaattagaac aattgattgg aaaaaatttc cactattatc aaacaggaca
     6781 agtggcggat tacattccag cattagctga agtggatccc aaacaattag gtatggcgat
     6841 ttatgatttg gatacaaaac aactgattga gggaggagac gccgatgtgc gctttgccat
     6901 cgaaagcatg tcaaaagttc ccgtattgtt attagcaatc aaagacaacg gaatagaaaa
     6961 agtctttcaa acaatcaaca cggaaccaac cggttttgcc ttcaattcta tcatgaatat
     7021 ggaaatcaat catcgcaaac atccaatgaa tccttttgtt aatgcaggag cgattgcaac
     7081 aacctcgttg attgccggta aagatgcaga tgaaaaattt gagcgaatct tgtcatttat
     7141 gaaagagatc tgtgatgatc ctaatatcac attgaatgaa gaaatctatc attctgaatc
     7201 aagaacaggt gatatcaatc gctctcttgc ttactatatg aaaggtaatc aaatgatcga
     7261 aggagacgta ccggagatac tcgatgctta tttcagacaa tgctccctca atgtcaccgc
     7321 tacaggcata gcaaaattag ctgctgtgct ggcaaataaa ggaattgctc cttggaatgg
     7381 caaacaaatc attactgaag aaagtgctac aatcgtcaaa tcaattatga caactgctgg
     7441 tttgtatgat gaatcaggag agttttccgt ccatgttggt gtacctgcaa aaagcggtgt
     7501 aggcggcggg ttgatggcag ctgtgccaaa tcgttacggc ataggtgtct tcagcccggc
     7561 actagatcca tttggtaaca gcgcagctgg tatccaattg ttgaaagatg tagtcaaaga
     7621 actagacgct gacatctttg aataaccatt cttgaaagag gctggggtaa aagtccaaac
     7681 ggctcaaagc tacctacaat gaggctgaaa ttgtgagctt gtttgacttt tgtcccagtt
     7741 tcttttttta ttggtttttg aaagggcttt tctaaataaa aaggaaacaa aaatacgatt
     7801 tacagatatg attaaataaa atcataagaa aaactggagg cgtgtatcag gaatgctgga
     7861 aaattacatc gagcgaaata tatttagaaa agtgtatctg tgtgaacaat tatttgaatt
     7921 ccaagaaata gacatcgaac aaacagctat ttctctaagg gtgactacac caacgatcct
     7981 tcacgatcta gaaagtctag ccgagtgtct agaatattgt ataaaagaac aagtaagaga
     8041 gaagcataag tataaactcg tattcaaaca tggtattgct ctttctgagc tcacacagtt
     8101 tctgtacggt caatcttatt ttttaaagtt tttaagttat tattttaatg gtatattcac
     8161 gagtacagaa ctggctgatc ttgaatttat ttctttgagt aaagtatata caatcaaaaa
     8221 aatcgtattg gattttttta aagaaaatga ttatttgaaa aataaagaaa tcattatccc
     8281 agaatttgac tcgcggaaca tcttgctagc tttagtacgt tatgtcaatt gggaaggcta
     8341 tgaaaataaa aatccgtatg tagaagaagc ttgtaacgag ttgattgatt atgtagagac
     8401 tcattttttt aaaagaagat attcggaaga tgaaaagtcc tttatcatac gagaaataga
     8461 gatcgcaatc ggaagaaagg catttcccct tggactgaaa gaagaagata agaaaagcgc
     8521 agaaacgaag ccgttatttc aattagtctg tcaaggattg gaagagcaaa aaggaattct
     8581 agacttacaa gaagaagatg tctattatat tttttctttg ttcaacagta gaaattatac
     8641 caatgagaac atggagctgt taagaaaaga tttcgaagtt gtttataaaa attttgttct
     8701 caatgaccta tcactgaatg aattgatttt acagattatt agtatcgctg aaatcgacga
     8761 tgcagaaaat tttattttca agcaatcctt tttacaattt gtccgtacgt tgtgggcaga
     8821 tggacaagta tttttaccgg aaaggatcta tcttctatca gaaaaagaac aacttctgta
     8881 cggaaaaatt gtagaaatat tggaagagtg gaaaaagaaa aatcaaatcc aactaagatg
     8941 gaatgaaaat ttcattcgaa aattcgtcaa aagtctttct ttgatcaaca gtgaacaagc
     9001 ggggagacag gaaatagaaa tttttgttgt ttcagaaagt tcagtcaaac aattttttta
     9061 tcgaacccaa tttcatttgt atgcggaaga aggcatcgct gaaataaatc ctattttatt
     9121 tcgttcatta gaagaattgc ctgatgaatg tctatgtgcg aaaaaaagag tggttttgtg
     9181 cgatgctgct agctatcaaa atggattaga aactgaaaag acaaagatct atccaatctc
     9241 attaaaaggt gcaaacatcc atttgtatca tattgctcag gaacttcacc tattaaaaaa
     9301 acatatttct tgatgagacc ttaattagga gaccttctac aaagcttttt aattgtctgt
     9361 agaaggtttt tatttgagtc ctgattcgtg cgaagatcta cttatataac aagctttctc
     9421 tgaaattttt ttaaaatgct attgacttag agtcaactct aagtagtaga atagataaag
     9481 tgtaacaaat ctattttcat taaaagaaga tagtacggag gagagaatgt attatgagta
     9541 cagtattaca tgtattggat gcaatcaata gccccgcaga tgtcaaaaaa ttatctgttg
     9601 aggaaatgaa acagttggca gaagagatgc gccaaaaaat cttgcaaaag gacagcgatg
     9661 taggtgggca cgttggtccg aatctaggtg tagtagaatt aacgattgcg tttcattatg
     9721 tatttgattc accaaaggat aaaatcgttt gggatgtttc ccatcagtct tatggtcata
     9781 agcttttaac tggtcgaaaa aatggttttg aaaaaggaca ttaccgtgaa gtgagcggat
     9841 attccaacca acatgaaagt aaacatgact attttacagt ggggcacaca tctacatcta
     9901 tcagcttagc aacaggttta gctaaagcga gagatctgaa gaaagaatca ggaaatgtgg
     9961 tagcatttat cggtgacggc tccctaagtg gtggcttagc ttttgaagga ttgaacaatg
    10021 gtggtgtttt acaatccaat ctaatcgtat tagtaaacga taatgagatg tctattgatg
    10081 agaatcatgg cagtttatat aaaaacttag ctgagcttcg tcaaaccaac ggtaaaagca
    10141 gcaataacct atttaaagca atgggatttg attatcgtta cgtggataat ggaaacgatc
    10201 tggaaacggt gatccgttta tttgaagaag taaaagatat tgatcatccg attgtacttc
    10261 acgtccatac ggaaaaaggt cgcggttatc agccggcaat cgataataaa atgaaatatc
    10321 attggcatgt accatttgat ctgtccaccg gggaggcaaa gcaagtaact tctggagaaa
    10381 catttaatat gatcatcatg gattatttgg ataagaaaat gcaaacaagt acagctccta
    10441 ttgccgcagt caatgcagcg ataccaggcg cctttggact gaaaacattc caagaaaaac
    10501 atccagatca ttattttgac gtggggatcg ctgaacagca ctctatcact ttcgcttctg
    10561 ctttggcttc tcagggagta cgtccagtcg tcttccaatc aagtactttc ttgcaacggg
    10621 catatgatca attatcacat gatttagcga tcaacgagaa tccagtgatt attttagtcg
    10681 gtggcggaac gatctcagct agtgaccgaa cacaccaagg aacatttgac attccttact
    10741 tatcaagtat cccgaacatc aaatatcttg ctccagcaac aaaagaggat atgatctcta
    10801 tgctagattg ggcgttcgaa caaacagcgc agcctgtagc aatccgaatt cctacacatg
    10861 gtgtagaaca tggtacagct atcgcaaatg attatagtat tccagcctat caaacagtaa
    10921 ataatggagg aaaagtagca attttagctt taggcggttt tcttgaatta ggaaaagaaa
    10981 cagtaaaagc ttttagaaaa aaaggaatcg aagcaacgtt gatcaatcca ggaacgatca
    11041 cagaaaatga cgtagaaaca ttagataaat taaaagaaac acacgaatta gtcatcacat
    11101 tagaagatgg tagtttgtca ggaggatttg gcgaaaatat cagtcgttat tatggtgatt
    11161 cttcaatgaa cgtattaaat tttggtgcag agaaagaatt cacggatagc gttcctgtag
    11221 ggcagcttta tgaacgttat catttaacac caaaacaaat cgttgaagat agtctgcgtg
    11281 tcttgaatat tcaataattc attatgctca ccatccagat aattgtttat actagtatct
    11341 ggatggtttt ttcattataa aaagcaaagg ggtggatgtt atgtatcagc aagtagaaga
    11401 atatgtcaaa aagttccaag aaaaatatcc tagttatcaa tcagaaaaat taggtttctt
    11461 ttcatttggg gatacagaaa aaatggcaga cgagttgagc gaactagttg taaaaaagat
    11521 aaagactggt acatcaagtg gttacgatct gtataaacaa gagaatgagc ctttaccaaa
    11581 agttggtcaa ttagacgtgg tcctgaatgg aaaaaatgaa ccagtttgta tcatcaaaaa
    11641 tataaatgtg accatcttgc cttttagtga agtcacgaaa gagcatgctt ggaaagaagg
    11701 agaaggggat cggacattag cttattggcg gaaagtccat gctgagtttt ttaaacatgc
    11761 ttataaagaa gcgttgaaca tagaatttac agaagagaag ctggtcgtat acgaagaatt
    11821 tgaagtaatt ttcttttagt aagaaaggtc tgctgaaaga aatagctcat tattgtctcc
    11881 tgaatagaaa agggttacat ttttatatga agctgtattt ttatataaca ttactggagg
    11941 agatattgtg gatacactgg aacaaatcaa aggcggagtc gtcgtttctt gtcaagcttt
    12001 ggaaaacgag ccgctacaca gttcttttat tatggggaga atggctttgg ctgcaaaaga
    12061 aggcggagca gttggtattc gagcaaatac gacagaagat atcaatgaaa tcaagcgaat
    12121 cgttgattta ccggtaatag ggattatcaa aagagattac gatgggtcag aagtgtttat
    12181 tactgcgaca gaaaaagaag tggaagaact tttggagacg caagcagaaa tcattgcact
    12241 ggatgcaact tctcgtaaac gtccgacaga aaaaacaact gctgaacttg tccaaatgat
    12301 tcacgaacac ggtcggttag ctatggcaga tatttcgact tttgaggaag cgcttcaagc
    12361 gcaagaagat ggttttgatc ttttgtctac gactttagca ggctatacag aatattcacg
    12421 aaagacgcag acacctgatt ttgatttatt gaatcaaatc atagaacaag tcgatatccc
    12481 agtaattatg gaaggacata ctgactctcc tgaacaagta gagaaagcat atgaattagg
    12541 tgctttttca gtcgtagttg gatctattat cacccgtccg caattgatca ctaaaagata
    12601 tgtcgaagcc gcaagtaaag caaataacta aaaaacacgc acggcacaga ttcttgacaa
    12661 aaaagaaaaa ttgatagata gtttaaagca gattctaaga agatgaaaaa agcattactt
    12721 ttcattttgt cttcaagatc tgctttttaa cgaattttat agaaagaagg cgaaaccatg
    12781 tttgaacgga gtccttcaga attgacagaa cgtgaaaatt acaagttgct gattggttca
    12841 gtcatcccta gaccagtagc agtagtaacg actaaatcag caaaagatat agtgaatatc
    12901 gcacccttca gttacttcaa tatcgtcagt tcgaatcgac ccatcttatc cttggcgatc
    12961 cagagaaaac aagatgcagt aaaagacaca gcaaagaata ttcttgagac aagagaagct
    13021 gttatccata tccttgatga ggacaacgta gaagaagtaa ataaaacagc agccaatctg
    13081 cctaatgagg aaagcgaact gtacctgact gacttgactt taactgattc agtaatcatt
    13141 tcagtaccag cattgacaga agcaaaagtt cgttttgaaa catccttata tgaacatgtc
    13201 gagatacgga ataaaaataa agtaacagct gatttatttt tgctagaagt acagaaatat
    13261 catttaaatg aaacagtcta tgatgataag acaggaagga tcgatccaag aaaattgaat
    13321 gctgtaagcc gtttggcagg aaatgattat gcagcaatag gagaaatttt cacgattgca
    13381 cgtcccgaat aaaaaggagc actagttatg ttaaaaataa gctataaacc atcgacagat
    13441 tcaaaagaaa tgaaaaaaga atatgaaaca gtgaatgatt ttctgcaagg gcagtactta
    13501 gaagttccgc cattgcaaga ccattttgtc gttactactg ttactttaga tggtaaggaa
    13561 atagaaatgc cagatcaaac gattagcgga ttgtttaatt actttaacaa ataaatattt
    13621 attccgaaaa gtgaaaaaac atataaaaaa acacataaaa ctaaaaaatt atcaaagaat
    13681 cctggtgcaa ctgaaagaat ttgcaacggg attctttcaa cttatttgtt atttttttct
    13741 aaaaaatatt aaagattgtt aaatttcact atttcatttc aaattccatt gcctaatcat
    13801 taggaaaagt ctatcatgaa ctcgtaaata gaatatagta ataaccttgt taggtgaggc
    13861 tcctatacaa acataggctg ttgcccagaa acgtcgaaag tcgccaatgg gtaaaacaga
    13921 aactgttgga ttaaggcttt ttccaatagc taagaatgtt ttctttacgt tgtatagtgc
    13981 taaaactcgg acgatgagat gatgctaggt cagaattctt gttcgaaaag gtttctgacc
    14041 ttttctttat atttttgtga ctgacttatt tgatgagaca aactcgctcc tcacctgaca
    14101 agtggattgc tgtgtgagga ggagatgcgg tgaaaaaaga tcgattggtg gattttgggt
    14161 ccttatttga ctttgtccat gatcggtctt ttagaagtat acagtgccag ttcttatcgt
    14221 ttattgcaag ccgatgaaaa tacaaaaagt ctattattgc gtcaactaat tttcatattt
    14281 ttgagttgga gcgtgatctt cttagctcgt tcagtcaaac tacactattt acttcaccct
    14341 aaaatagcag gatacggttt agccttatcg attttctttt tagtattagt aagaataggg
    14401 atattcggtg tcactgtcaa cggcgcacaa cgttggatct ctctgtttgg cattcaattc
    14461 cagccttctg aactggcaaa tctttttttg attttttatt taagctggtt ttttcgtgac
    14521 ggaaatagta gcccaaaaga tctaaaaaaa ccattcctga ttacagtagg tataactttt
    14581 ctgattttat ttcagccaaa gattgctgga gcattgatga tcctttcgat tgcgtgggtc
    14641 atattttggg cagcggcggt tccatttaaa aaagggatct atctaatcgt tactttttct
    14701 gcattgctga ttggagcagc aggcggggta ttatatttag gaaataaagg ttggcttcca
    14761 cagatgttta atcatgctta tgaaaggatc gcgactttaa gagattcttt tatcgatagt
    14821 catggtgcgg gctatcaaat gacccattcg ttttatgcac tatataatgg tggcatattt
    14881 gggcggggat taggaaatag tatcacaaaa aaagggtatc ttccagagac agaaacagat
    14941 tttatttttt cgattattac agaagagctt gggctaatcg gtgcattgtg tgtgcttttc
    15001 ttattgttct cattatgcat gagaatcttt tgtttaagca gtcgctgtaa aaatcagcaa
    15061 gctggattgt ttcttttagg attcggaact ttgctattcg ttcagacgat aatgaacgtg
    15121 ggaagtatcg cggggctgat gccaatgact ggtgtgccat tgccatttgt tagctacgga
    15181 ggaacaagtt atctgatcct ttctttagga atcggaatca cgttgaatat ttcttcaaag
    15241 atacaggccg aagagttggc gctctatcga cctgaaaaac aataaagaga aactgagaaa
    15301 ctctcagttt gaattatcat aaagtacaat cttttatttt tcaagcgaga ggttctttta
    15361 gaaagaggaa ttcgcaatga aagtatctca aaaaatcata ttatctattt tgttactgct
    15421 tacattagta gttggctatt tttcgattga gtttatccat ggattttcgt ctgcaaaaca
    15481 gagttcaact gtgaaaaagg tagagccgaa aagtatccct accacactaa atgtggcttt
    15541 gattggttca gatgctcgtt cgaaagacga aaacggtcgc tcggattcac ttctggttgc
    15601 acaatacaac cagaaaacac aacaagcaaa actgatctct atcatgagag attcatatgt
    15661 cgatattcca ggttacggaa tgaataagat aaatgcagct tactcttatg ggggagttga
    15721 tttattaaat caaacattaa aggaaaattt caaatttgaa gctccctatt atgcaagtat
    15781 cacatttcaa gattttatcg attgcgttaa tgaactgttt cctggtggag tcaagatcga
    15841 tgcagaaaaa tctctagatt tagatggcgt atatataaac aaaggagagc aagtgatgga
    15901 tggtaatact ttactccagt atgctcgatt tcgggaagac aaagaaggag acttcgggag
    15961 gatcagaagg cagcagcaag tgatcaaagc tatctctcag cagctgaaag acgtaacttc
    16021 aatattcaag ctacccaaag cggttgggaa attacttggt agtatccaaa cgaaccttcc
    16081 agaaagtgtg cttctggatt gtggtatgga tttcctcaaa gacatatgtt agaataaaca
    16141 ggtataaata gtgaaataaa ggaatgacaa gcaagagaag gaggaaaaaa tgaaaagaag
    16201 tgacaagcac ggcaaaaatc gaacaggcgc ttatattgcc ggcgcagtga tcttaatagc
    16261 agctgcgggt ggcggttatt tttactacca gcactatcaa gaaacccaag cagtagaagc
    16321 tggagaaaag acagttgagc aatttgtcca agctttgaac aagggagatt ataacaaagc
    16381 tgcagaaatg acatcaaaaa aggcggcaaa taaaagtgca ttatctgaaa aagagatctt
    16441 agataaatac cagaatatat acggtgctgc tgatgtcaaa ggacttcaga tatcgaatct
    16501 aaaagtagat aaaaaagacg attctactta cagtttttca tataaagcaa agatgaatac
    16561 ctcattaggt gaattgaaag atctttctta taaaggaaca ttagacagaa atgatggtca
    16621 aaccacgatc aactggcaac ccaacttggt ttttccagaa atggaaggaa atgacaaagt
    16681 aagcctgacc acacaagaag cagcaagagg gaatattata gatcgaaatg gtgaaccatt
    16741 agcaacaaca ggcaaactaa aacaattagg agtcgttcca agtaaacttg gagatggagg
    16801 cgaaaaaaca gccaatatca aagcgattgc ttcctccttc gacttaacag aagatgctat
    16861 caatcaggcg atttcacaaa gctgggtaca acccgattac tttgtcccat tgaaaatcat
    16921 tgatggagca acgccagaac ttccagctgg agctaccatt caagaagtag acggcagata
    16981 ttatcctttg ggtgaagcag ctgctcagct gattggttac gtgggagata tcacagcaga
    17041 agatattgat aagaatccag aattaagcag taatggaaaa atcggtcgct caggtttgga
    17101 gatggctttt gataaggatc ttcgtgggac aacaggtggg aaattaagca ttacagatgc
    17161 agacggtgta gagaaaaaag ttctgatcga acatgaagtt caaaatggca aagatatcaa
    17221 attgacaatc gatgcgaagg cacaaaaaac agcttttgac agtctaggag gaaaagctgg
    17281 atcaactgtt gcgacaacgc caaaaaccgg tgatcttctt gcgcttgcta gctctccaag
    17341 ctatgatcca aacaaaatga caaacgggat ctcacaagaa gattacaaag cttatgaaga
    17401 aaatcctgaa catccattca tcagccgatt tgcgacaggt tatgctcctg gatctacgtt
    17461 taaaatgatt acagcagcaa tcggtctcga caacggcact atcgatccaa atgaagtgtt
    17521 gacgatcaac gggcttaaat ggcaaaaaga cagttcttgg ggatcttatc aagcaacgcg
    17581 tgtcagtagt gatgtatcac aagtagactt aaaaactgct ttgatctatt ccgataatat
    17641 atatgcggca caagaaacgt tgaaaatggg tgagaaaaaa tttcgtacag gcttagataa
    17701 attcattttt ggtgaagacc ttgatttgcc aattagtatg aatccagcac aaatttctaa
    17761 tgaagatagc tttaactcag atatcttgct agctgatact ggatatggac agggcgaact
    17821 tctaattact cctatccagc aagcagcaat gtattctgtt tttaccaaca atggcacact
    17881 tgtctatcct aaattgattg cagataaaga gacaaaagat aagaagaatg tcatcagcga
    17941 aacagcagta caaacgatcg tgccagatct gagagaagtt gtgcaagatg taaatggtac
    18001 agcacattct ctttctgctt tagggattcc gttggcagcg aaaactggta cagcggaaat
    18061 caaagaaaaa caggatgtaa aggggcaaga gaacagtttc ttgtttgctt tcaatcttga
    18121 taaccaaggt tatatgatgg tcagcatgtt ggaaaataaa gaagatgatg attcagcaac
    18181 caaacgagca tcggaactat tgcaatacct caaccaaaat tatcaataaa aaattgcttt
    18241 ttaagtacag taaaaggact gtggcgttat cgtcacagtc cttttttcaa ataaacggtt
    18301 ttcacgatgt ctctttcaca acttcttttt gatttactca cacttcataa actttttttg
    18361 taaaatattt gagaacaagt ggagaaataa gtgtacttaa taaaatcacg ataactaaag
    18421 gtgaatagta ctgtggttcg atcaattgac tttgctgtcc aatttgtaaa atgatcaaag
    18481 ccatttctcc acgcgaaatc ataccagcac cgaccatcaa tgaactatgt tgagaaaaac
    18541 cggcaatctg agcaccaaaa taacctccaa gcaatttggt caaaatcgct acaagcgtca
    18601 atatagaaat aaagagtagt tgttcactaa agtcagaaaa atcaacttct aatcctacac
    18661 tgacaaaaaa tactggtata aatactgcat atcctaaagc ctctacattg tggtatactt
    18721 cttctttaac ctttgtctga ctgacagcta tcccagcaaa aaaagcacca atgacagagc
    18781 taagcccaac aagatccgct acgtaagaca ttcctaaaca aataactagc gatacgatga
    18841 taatagaaga atttgcgtac actttttctg caaatgaaag taggaaaggc gcaatccatt
    18901 tgactaataa gaaaataaaa acaaaataaa ttagctgttc aatcaaaaca agcggtaaag
    18961 aagcattgct agaagcttcc cccgttagaa aagataggct gaaacttaga actaaaacga
    19021 ctaaaatgtc atctaccaca gaagcaccca aaattgttga tccttctttt gtattcacta
    19081 cgtttagttc ttttaatact tctactgaaa tactgacaga agttgccgca agaataatcc
    19141 caaagaaaat cgcttcattt cccgaaactt ggaatgcttt gcctgtcaac cagccaaaaa
    19201 caaccgggaa gatgatccca agcaaagcaa cgaacatacc aggtcggaaa tattttttca
    19261 aaagagataa atcactttcc agaccagcta aaaacattaa taagatcaca ccaatctccg
    19321 aaaagtcatg gactagaata tcaggtttga cccaattcaa tccagcttgg cctagcaaaa
    19381 caccaacaag taattgtcca atcactgctg ggatacctaa tctccgcgag atatgtgagc
    19441 caatcgttgt tgaaatcaat atcaggcata aaataccaat aaattccatt ctcatcattc
    19501 ctttgtataa aatatagccc gaacttagca taacatacat tattgaaaaa ataggaaaat
    19561 atactcacaa aaaaaccaac aatccaaaag atttttttgg attgttggtt tttatacggt
    19621 ctattttaat aactaaaaat gattaacgta tagtcatttt tcttattctg atgaaattga
    19681 taatctcctg gatgcccatg aaaatcaaaa taaagccgaa tatttggaat agaagcatca
    19741 aacttttgaa tggattgaac aataagacga atccgccaat caacaacaga atactactat
    19801 aaacactcca acttttagct tttgtattca tgctgaagaa caactggaac aagctgttga
    19861 tgataacagc taatccaaga agaatcggca ggatagaaac gattgcaggt gcaaaagcat
    19921 agacgatcag agctaagatc aggaaaaaaa gaccactgaa cagaccgata ctccaagaac
    19981 ctgttttcct tttaaaacgg taagcctcaa aaagattcaa caacccaagc aaaacaagat
    20041 aggcggtgat cagataaccg ataaaatgaa aaacagcaga agggtttagc acaatcgcaa
    20101 tcccagaaat aatataaaca gcagctctta ataaggcgta tttttgaata ttttgtttaa
    20161 tcgtctcaaa catataagaa aacctccttt gacttatttt aacgtgaact agtcatttta
    20221 ccaaattaaa tgttacaaaa tgagcgaagg agaagaatat ctctggaaaa atcaacttct
    20281 gaggatcttt tccatttttt tgccttttgc tagctcatcg atcattttat ctaaataacg
    20341 aatttctttc atcaagttat cctcgatgtc ttctactcgt acaccacaaa caacacctgt
    20401 aatcaaggaa cgtgaaggat tggggacagg ggcttccgca aaaaattgtt cgaaagtcac
    20461 ttgtttttgt agttgatatt ctagttctgt ttgggaataa cccgtcagcc aacaaatgat
    20521 ttcatctact tcctctttta tacgatcttt tctctccgct tttgctacat acataggata
    20581 aacgcttgca aaacttgtcg taaaaatacg attttgcgcc ataatcagtc acctttcttt
    20641 ttttcaaatt atttactact tatagtatat aagaaaaaga gaagaaaaag cgattattca
    20701 aaaaaacaaa aaggattgtg acaaaattct tgtcaccatc cttttttccg ctctctgact
    20761 ttttacaatc ttcatagctc aagtgcgcat cagataatcg aatgctccta aagctgcagt
    20821 agctcctgaa cccattgaaa caatgatttg tttgtatgga ctatctgtac aatcaccagc
    20881 tgcgaaaacg ccggggatat tcgttgcgcc atttttctcg gtcactattt catttcttgg
    20941 attcatttcg atcgttccat ctagccaatc cgtattaggg agtaagccga ctagaatgaa
    21001 tactcctgaa acagctagtg tatgcatctc catcgtacgg cgatcgatat aggagagaga
    21061 ttctacctga ttcgtaccgc tgatttcttt cgtcgctgca tgtttgataa cagtgacatt
    21121 cgcaagagag actagtttat cctgtaagat ttgatctgct tttaattctg gtaagaattc
    21181 tagaacatat acatgttttg ctaacccagc caaatcgatt gctgcttcaa caccagaatt
    21241 accaccaccg ataacagcaa tctcttttcc tttaaataaa gggccgtcac agtgtgggca
    21301 ataagcaatt cctttatttt taaactcttt ttcgcctggt acattgatag aacgccagtg
    21361 cgcacctgtc gcgatgatgg cggtttttgc tttaagtgat ataccgttag ctaagccaat
    21421 attaataaaa tgttgctctt tatttaagga aacggcctgt tgattcatca taatgtcgat
    21481 agggtaacta cgcacatgac tttctacttg ctgcatcaat tttggacctt ctgtgtaaga
    21541 ggtaccaatc atattttcaa tccctagtgt ttcaacgact tgtccgccga aagaatcagc
    21601 gacaagtcct gtacggattc ctttacgtgc tgcatagata gctgcactac tagctgctgg
    21661 tccaccgcca atcactaata catcataagg ttctttttca aacaactctt cttcaatcaa
    21721 agggccagtg attttttcaa caatttgttc gatcgtcatg cgtccgctac taaattcttc
    21781 tccatttaaa aacacagttg gcactgccat gattttttta tcatcgattt ctttttggaa
    21841 catcccacct tcaatcatcg tatgagtaat atttggattt aatacagcta atatattcaa
    21901 tgcctgtaca acgtcggggc aattatgaca agtcaagcta acataactgt caaaatgcaa
    21961 tgtttgtgtt atttttttga ttttaagact caaagattca ctgattttcg gtgcccgtcc
    22021 actaatttgt aacatagcca gtaaaaaaga ggaaaattca tgaccgaggg ggataccagc
    22081 aaaaacgatt ccactttctt tgccaactgg attgatagaa aaactaggtg tgcgcatcga
    22141 atctcttttt tcccaagaga ttttaggaga catttctgct atttccttcg taaattcagc
    22201 tagtttttga ctattttcac tattatccaa actaacagaa aaaacaatag gagattcaat
    22261 cagtgctaaa tattgttcga gattttgttt agtttctttg tctaacatat ccaccaccta
    22321 aatctttcca acaagatcaa aacttggttt caatgtttcg ccactttctt tccattttgc
    22381 cggacaaact tcacctgggt gggtacgtac atattgagca gcgcgaatct tatcaatcag
    22441 tgcactagcg tcacgaccga ttccatctgc attgatttcc atagcttgaa cgattccgtc
    22501 tggatcaata ataaatgttc ctcgctgagc taatccttgc tcttcatcca aaacatcaaa
    22561 aatacgagaa atctgatgag acggatcacc gatcatcacg tattcgattt taccgatagc
    22621 atctgatgta tcatgccatg ctttgtgagt aaagtgggta tcggtagagc aagaaaagac
    22681 ttcaacacct aaagatttca atgtactgta ttgttcttgt aagtcttcta attcagtagg
    22741 acaaacaaaa gtaaaatcag ctggatagaa gcaaagaata ctccagttcc ccataagatc
    22801 tttttcactg acttctaaaa attctccttg atgataagca tgtgcattaa attcttcgat
    22861 ttttttccca atcaatgaca tagtaaaacc tccaataata attatttatt tataattatt
    22921 gtaatttagt tggagttgca aagtcaatgg atattttgtt atttaataaa gattactcaa
    22981 aaacgaaggt taattataaa aatagaagag gtcgcaagaa aatgctactg ctggaaatac
    23041 tcgggataac gttgagtaac agtttcctgt tctttcagca tcatgtgtaa gtgcaatccc
    23101 gtttgaaatc gagcttcttc tggtttttta tcaactaaag ccttgagtaa atcataatgt
    23161 tgttccatga tcgtttccca tggaagcccc tgaatggtca ctcgtaacca gcggaaacgt
    23221 tctaaatggg tattatggtc atctaaccag ttccaaactt cttttcttcc tgcaatttcg
    23281 aaacaagctt catgaaataa attatctgca cggaaaaaag cgcgttcgtc atttattttg
    23341 actgcttttt cttgttcttc taaaatcgtt tctagcacta ttcgtgtttg tgtgtccaat
    23401 ttggaacaac attcaatcat gatttgctct tccaactgtt ctcggacaaa gcgagcattt
    23461 tctgcagaaa caagattaat tttggaaaca tacgtaccac tttgaggtat cgtatacacg
    23521 agttcttgct gacgtagttg aatcaatgct tcgcgaatgg gagtccggcc gatagcaaga
    23581 tgttcctcca gtgccttttc agatattttc cttccaggtt ctaagtcagc atagataatt
    23641 tgtttacgaa tcgcttgata agcttgtgat tgcaagctgc ttttcatctt tattcctcca
    23701 aaatcatttc tatgaacgta gtataacaga agaggtctga aaaacaatct ggtatgtcac
    23761 attaactagt aaatttgtat aaatagtaaa attttggttg acatagcgat ttttattgca
    23821 taaaattcac ttgaatacaa aaactaatat gttagtttag gaggggaaaa atgattgatt
    23881 taaacaactg gaggaacttt atccctgaat tatctcaaaa agaagtagaa atacctcatt
    23941 ttgaccgtgc atcattaaga gaaaatggac aaaaaaatcc tgtctggatc catttcggtg
    24001 gcggaaatct ttatcgagga tttcatgcag aaatcgctca acgtttagcg gatctaggcg
    24061 aattgtccac tggtgtcatt gtttgtgaaa cattcgatga agaaataatt gaaagggctt
    24121 accaagattt tgatgatttg attcttgaag tggtcatgcc aagcagtgga gagttcgtca
    24181 aacgtatatt agctgcgaca gctgacagtc tgtattgtca tccagattgt tctgaacact
    24241 ttgataagat gattcgacac tttgaaaatc ctagtttaca attagttact tttgctatta
    24301 ctgaaaaagg ttatcgattg aaagatacaa ataataaata tataggaccg attgcagtcg
    24361 atataaagaa tggtccaaag aagccatcac atacaatgag tattcttgct gtgctacttt
    24421 ataaacgttt tttatctgga gcttggccga ttgcacttgt ctctacagat aatttttcac
    24481 aaaacggtag tcaattacgt acttctttgc taacgatcgc aaaagaatgg caaaaggaag
    24541 gttatgtaca aaatacattt atccaatact tatcgaatga agaaattgtt gcgtttccat
    24601 ggacgatgat tgatcgtatc accccgaatc cttccttgtc agttagcaaa atgttggcaa
    24661 aagagggctt ttcaaatatg tcgattttcc aaaccgcaaa aggaaataat attgctccat
    24721 ttgtcaatac agaggacatc cattatttaa tcatggaaga tcattttccc aatggacgtc
    24781 cgaaattcga aaaagctggg gtattcttga ctgatcgtgc aacggtagat aaagcagata
    24841 cgatgaaggt gacgacttgc cttaatcctt tgcatacgtc tttagctatt atgggttgtt
    24901 tactggggta taggagcata gctgaggaga tgaaagatcc agatttatcg ctgctagttt
    24961 ctgaaatcgg gtacaatgaa ggcctcccag ttgtggagtc tccaggtatc attgatccaa
    25021 agatctttct ggaagaagta attactgtgc gcttttctaa tccaaatatt cctaatatgc
    25081 ctcagcgaat cgccacggat acctctcaaa aggtggcgat tcgttatggt gagacgatta
    25141 aaaaatatat ggaaatagaa gttaaagacc cgcagacact tgtattcata ccattgactc
    25201 tcgctgcttg gcttcgatac cttattggca ttgatgatca aggaaaacca ttcatcccga
    25261 gtccagaccc actattgaca gaccttcagc ataagctttc cgatattcaa ctgggtacgc
    25321 aagatacatc acatattcat gagaaaatgg ctcctatttt gtcaaataaa gaaatttttg
    25381 gtgtagatct ttaccaagca gagcttggca gaaaaataga agaaatgttc atcaagatgg
    25441 tagcaggacc aaatgccgta cgaaaaacat tacaggatta cttacaagaa catggaggaa
    25501 atttatcatg gaaatgactt ttagatggta cggatcacag gaagaaaaga ttaccttaga
    25561 tgaaatcaga cagattcctg cggtcaaagg gattgtaggc acattgatgg atataccagt
    25621 aggagaggta tggcctaggg agaggatcaa agaactaaaa gaagaaattg agtctcgtgg
    25681 gttaacacta aaagtaattg aaagcgtcaa tgtgcatgat gccattaaaa ttggattacc
    25741 ttcccgtgag cagtatatcg aaaactataa gcagacaatc cgaaacttgg cagaatatgg
    25801 aatagaagtc atctgctata attttatgcc tgtatttgac tgggtgaaat ctgaccttga
    25861 ctaccgctta gaagacggct catccacgtt agcttttata tctgatgata ttccagatga
    25921 tccaagagaa atcgtcgcgc gcatcgaaca ttccagcaat gaatttggat tgccgggatg
    25981 ggaacctgag cgcttagctc ctatcaaatc cttgcttgaa gcctatgcat cagtagacga
    26041 agaaaaactt cgagaaaatt ttgcctattt tctccaatca atcatcccaa catgtgaaga
    26101 ggtaggggtc aaaatggctg tacatccaga tgatccgcca tactcgattt ttggattagc
    26161 tcgaatcgta aagaatcgag aagatttaga ttggttgtgt cgcatagtag acagccctta
    26221 taacggaatc actctttgta cagggagtat tgcagaagat ccagaaaatg atgtatatgg
    26281 gattttagca gaattttgcc aaagagatcg aatcccattt gcacatgttc gaaatattaa
    26341 atttttagct aatcgagatt tctatgaggc accacataaa tccgaatacg gttcattaga
    26401 catgtaccgc atactaaaaa caatgtatga caacggattt aacggataca tccgtcctga
    26461 tcatggaaga atgatctgga atgagacagg aagaccagga tacggcttat atgatcgagc
    26521 attaggtgct gtttatctaa atggattatg ggaagcaatc gaaaaaggaa acaaaagtaa
    26581 agataattag tgaaaaaaac tgtaatttta ttatgtaaat aagaaggatg ttcaaattct
    26641 tgatacataa atccggaggt tgttaataag cattcggatt tatgtatctt atttggtcta
    26701 ggaagtaact tgattttctt ttttcgattg atccatgagt gcttcttctt ttaattcaaa
    26761 gatatattct gagatcctca taatcacttt tttccagtct tctggtgtga tgattccttt
    26821 taaaatatag atttttttga tatgagaagg caattgtttc aaagggcagt cgctgataac
    26881 gatgttgcag ttctccataa aatcattttg tattttgatc gattcatttg aaaaaatttg
    26941 ttctatctta acgatcagat ctttactgat ataaaaatca cgcgtatagt tcacaccaat
    27001 cacaattcgc ggctgttttt tgtagcgatc atacaaatgt actaggtctt caaccatcca
    27061 ttgcacattt tccttttcta aaataactgg taacaagtgt tgattttgtt ctctgaaatc
    27121 catataaaat tgttcaatgg cggtttggac ttctttcaat acgctatgtt cttgataaag
    27181 catgaaagta ggaaggggcg tatttggttg attgaagtta agaaatccat tataaagttt
    27241 atttcgtgcg aatgccaatg agtaaagaat cttttctttt tcaggtataa acaaatcaaa
    27301 tacagtacaa agggactcca ccatttctct tgaataaaga acatgaggaa cgtttgcttt
    27361 ttttaaaagt ttgtattgct ccaagcttgt ttcttccgat tcgattttcg tgatagaaag
    27421 tcgagctaaa atattcacta agatgcgttg ttcgcgacaa attggcagat taggtcgcaa
    27481 aatatctaca gagagatcaa taaaaaagtc aatatattca tactctgtga attctttttg
    27541 tacgtctttc acagaagttg caggaaaatt ctctttacat atttttaata gaaaatataa
    27601 tttatctatc ataccgctat ttagtcggtc aagtacttct tttttaaaaa aagtattcat
    27661 cataaaagcc actacttgcg gatcttcatc ataaaattct gtagcagtac ttgaaaagat
    27721 gttccaataa atatctaatg ctgcatattg aatttgtacc tcttttccag aaaaagactt
    27781 tctgccatta ttagaaaagg agatagacaa accgtactat gctaaaaatg cattaatctt
    27841 tttcattttc gtatacaaat aagaggcact atagtttgtt tgctgactga aactgataat
    27901 cgaatttgtc tgacagctga acaaagaagt caagatctga taactgactg attcgttgca
    27961 gtatcttcca aatagacgat aatagcagta agccggatca attccttcaa aattcaactt
    28021 taaaaaaggt ttttgcttat caatatgcag ttctgttaga ttgagacgct caaagtcttg
    28081 ttctaattct ttgatgtata gtaaaaaatt tgattcagac atatggaaat gatctgctaa
    28141 atattgtgta gtaataaaga aacgatgttc agataggaaa agaaaaatat ctaattttgt
    28201 attgcttttt ttcttcaaga taaacgtttt aatcgcttct tgagtttgca tgaaagaggc
    28261 tcctttttac ttaaattgtt aaaacttgaa aatattactg tttttttcat aaatttagac
    28321 aaaaaaacag taaacatata ggtagaatct ctactatctt atttcttgca tacaaaaaaa
    28381 tcaaggagtg agagagttat gagatattca accatcttaa tatcaacatt tgcagcctta
    28441 agcttatcgc ttactataaa tcagacagtc cacacagagg agacagaaac agccaaatgg
    28501 acagaaacca agtgggccaa cgtcaatcga attacctttc aggatgaatt ttcatccttc
    28561 aattcaggag tcgcaaaatt aagaaaagga caaacagcga ccatcaaagc aaaaattgac
    28621 tattcgggag acttagcacc tatactacaa tcagctgtta catttgagaa tgttgatccc
    28681 actttgtcga ttggctatga cgagaacact ttgactatcc aacacaagca agcgatattt
    28741 accttcaccg ttacattaaa tcaggacttg ttaaaaccag cgctttttac tgtcaaggta
    28801 tcagatggac taccgaacga tcatcattta acgccgtata gtcagcggca gacaattgag
    28861 caagattcag ccatcgactc aggaggagat cttgttgaag aaccaacaga taaaccagaa
    28921 aatgaaaata agccagaagt accgcctaca gaaaatccag acggagaaca gaaaccggaa
    28981 atagaacctg gagaagaacc cgatacagaa actcaaccag agccagacaa taaatcaaaa
    29041 cctgaaataa cccctggaga aaaaccagat gtaactccag aaccagatac ggattctgga
    29101 aaccaaacag taccggaaac aaatccagac acagataatg aaactgaaaa tccagaaaaa
    29161 ccagaggtag atccagaaga aaaaccagat gtgactccag aaccagatac ggacgcaaga
    29221 gaccaaggaa taccagaaaa aataaacaaa aaaacaattc aagaggatgg aaaaaaagag
    29281 agtaaaaaat caaatctagc aattctaaaa ataaatgaag agcagctgaa taaaaaatca
    29341 cgaatatttg atagcgccca atcagctgaa accttaaaaa gtagcaagga tacaaccttt
    29401 gctgtcctga aacgaaaaat aaacagctac caaaatccgg agagtcacaa aacaaagtta
    29461 tactgtggag cggaatcatt ctattaagta tagcaacaat gctttctgca aaaagattta
    29521 aacaaaacag atctctctaa catttgaata atgtctgtga acgcattttt caaataaaaa
    29581 gaaatatcca gaaaatgacc ccaaaatacc agattgaaat ctgatatttg gggtcgttca
    29641 tactttatct ttcttcatat ttattttaag ggatatctgt ttcttttgga agatggttcg
    29701 ggatcttttt cactttcaat acatctaaaa agaaggtaaa gatcggaatg ccgacaatca
    29761 agccccaaac gccaaagaac cgttcgctaa caagtaagac cacaaatgta taaaaaatcg
    29821 gcagttctgt tttgctggac atcaacttcg gattcagcac ataagactca attagatgga
    29881 caatcaaaat cgtaatcagg atataaacaa catctcggat gcctccttgg gaataagcta
    29941 tgaaagatag aggaatacaa gaaatgataa cacctgctac tgggatcaga cttaaaatga
    30001 aaatcatgat cgctaaactc agcagctgat gaaagccaaa tacagccaag gcgattgtag
    30061 tgagcaacgt atttaaaaga gcgacaacaa attgagcttc taataccaaa ccaaatgtat
    30121 tgacaaactt atcggcaaaa tagtaaatat cttgaaagaa ccaagaaaat tcacttttta
    30181 aaaacaatct tgagaataca attgtttttt tcttttcaat cataaaaaag aaacttaaga
    30241 tgaatgacat agcaaacgcc actgccattt ttcctatatc ctgtaaatag ccaagcgcaa
    30301 tcgaagcgcc attttgaagc tgttcaaaaa aatcgtttcg ctcaatataa gtatggatat
    30361 attgtaaaac aggatctgca tcttttggct gatgctcgta aaaattaata acggactgga
    30421 tcatgtcaaa tgtttgatga ataagcatcg ggatatactt tgtgaatgcc agatagataa
    30481 ggtaaacgat cagtgtataa atcatgatag ctaaaacacc tgtagggatt cggacaaatc
    30541 gctgaatgat ttgaacaaga tgaatcatca aataagtaaa gataaatgtg agcaaaatgg
    30601 ttgtaatcat acttctaact aagaaaagaa caaaaacgac aaataataaa acagtgagac
    30661 ggcgtatttt ttcattcgcc aaaaaacgct gataaacggt caaatcgaca acctccaaat
    30721 aacaaaaaat aaacacgtta ttcattatat gatggaatat gaaaataaga aagagcaaaa
    30781 agaaaaaccg ctaaatgacg ttatcttatg agttggtttt cctcataaaa tcgttcatct
    30841 agcagtttca gccctttttc tggtcttgat gaaaattatc tagcattttt cgggtcagat
    30901 gttgcagtgt atccaattct tcctgttcaa gtggaagata agacttgatc ttttgtggaa
    30961 taccttctgc ttgtttttgc aacgcagcac cttgagcagt cagcgtaaca tttacgattc
    31021 tttcatcacc cgtttcacgc tgacgattaa tataattttt ttctgctaac ttttttagta
    31081 agggagtcag cgtaccagaa tccagacaca aatcatttcc tagctctttc actgaagtct
    31141 ttttcttttc ccataaaact aacatcacaa gatactgggt ataggtaaga ttcagcggct
    31201 tgaggagggg agtgtagtgt ctaatgattt ctttagaggc ggcatataaa ggaaaacata
    31261 cttgattaac taaatataga tcttccattt ttccacctcc gctgttttac tatagtgtat
    31321 catagcggat ttacacaaaa aagtctattc actaactgct ttcagagtaa cttctatatt
    31381 tccagctgta gcttttgaat acggacacac tttatgcgct gcctctaata attcttgcgt
    31441 ttcttccaga gaaagacctt cgatagatcc ttcaatctct acacctaaga caaagctcgt
    31501 ttcactttct gaataaaggg aaacttgtgc actgacagta gaagccccag agatattttt
    31561 ttgctgtttg atcaattcta atgcactgtt aaaacatgca ctgaaaccag ctgcaaacaa
    31621 ttgttcaggg ttggttgcat tttcgacgcg tttaccagga gctgcaatat tcaattcgaa
    31681 tgtacgatcg ggattatgca cttctccaga gcgtccgcct gtgttgatca ttttcgtaga
    31741 atacattttt ttcataaaat taccaccttt aattatattt tatacaattg aattttacac
    31801 aatataattg tggaaagcaa agaaatggat tggcataaga taaataagag aaagcacatg
    31861 aaacagacgc gctttctcga atagcaaaca tatacaaaaa atatcagaga caaaaaataa
    31921 tctcatcata aacattacat atatttctca aaaagttgtt ttctttcttc aaaaattact
    31981 tcacgatgga cctgatgaag catccataaa taaccaaaag gatctctgaa cattgagtta
    32041 gtcacaccaa agtccatcat ttctgtcatt tcttgaatct ctacacagcc atttcgtaat
    32101 gctttattat gtgtgtcctc gatatcagag acgatgatat tgaaccagat cgtatttgga
    32161 tgttcagcag taggagcagt caaaccaaga gacgtgtttt catccagcat atggaatctc
    32221 gtaccataca aggtaaaaat gacttcatta ttgcctctag ggtaatctgt tgcctcaatc
    32281 agttgtattt catcaaagat tgtttgatac agttctagtg ctttcaaact atcatttaat
    32341 acaaaatcga tttccgttcc tttatgcata aagatctcct ctccttttca gtcgaacagt
    32401 tactagattc ttttattata ccagctaaag aaaacgcatt caaaaaaata gcggatttac
    32461 ttaccaactc attcgattgg atgataagta aatccgcgtc ccattacttc tgctacgctg
    32521 ctgacaatga caaaggcact tggatcgatt tcttctatca atggtttcat tcgggaaaat
    32581 tcatgatcag tcacaacgat caataaaacc tcttttgact ttcgattata cccgcctttt
    32641 gcctctagca gggtaaggcc acgtccaatc tcagcactta agcgaaggcg gatgtcttcc
    32701 aaataatgtt cactcatgac cataacagat ttctttcgat tgatacctgt ttcgatataa
    32761 gtcatgacaa ttgaagtgat tgcaatagat aaaatagcat aaagaaactc ttctattcca
    32821 aaaataaaca gattaagaga aacaacgaat gcgtctgtaa aaaataagcc aatcgaagta
    32881 ttcaagtgga aatatttttt aaaaatgagg ggagggatcg tcgtaccgcc gctagaagag
    32941 ttgtttttat ataaaatcgc aactcctaaa gcaaaaatcg cacttccaaa aatgacagac
    33001 aacaaccgat ctgaagtaat cattgtttct ggaactattg caatgattaa aggaaaaacc
    33061 aagcttccga aaagtacttt aaaaaagggt tttttaccta aaaatagaag agctagtacc
    33121 aacataacga tattcaacac taaaataact atagctcggt caaagcctaa agcagcttcc
    33181 agtaatattc ctagaccgct gacacctcca gcagcaatat gatgaggccc taaaaacata
    33241 ttgatagcga ctcctaatat gaagagggca aaaataatct taatgtatgt ccatataaat
    33301 tgtctcgttt ctttcattta ttcacttcct taattcatta ataatactct tatcttatta
    33361 taacttactt ttcaccttaa gttaacttta attaataaaa aaattaggct agtctaaatt
    33421 attatgtttc attcttctag aatatacttc tacgccaaaa actgttaaaa aacttttact
    33481 ttagaaaatt ggagaaattg atcgcttaag ataaattcag gacactaaat agtacaggaa
    33541 gtagactaaa acttttaaaa gttttaagtc tatctatttg gcaagtttaa aaaataaaaa
    33601 ttcggtatca aaaaactgtt accgataaca tttttgaaag cgttgtcttt tgcttctcta
    33661 tcacttatag tgatgacgtc atattaaaac acaaggagga aatcaatgga tacagctgca
    33721 atttatcatc gaccggaaag tgaatatgca tttctatata cgaatacaag atttcgtatt
    33781 cggcttcgta ctaggaaaaa tgatatcaaa aaagtatatg tgctatgtgg agatccatat
    33841 accataacaa ctgaaaaatg gtatcaaaaa caacgaccaa tgaaaaaatg tctaagtacc
    33901 aatgttcatg attattggga aattgaagtg acgagcgaaa caagtcgctt acagtatgcg
    33961 ttccatgttg ttggggaaga taacacggac tgtttttacg gtgatcaagg aatttttcct
    34021 tatcgagaaa atgtgattac tgaaccaaat ttttattttc gaatacctta ttttcatcaa
    34081 atcgatcgat tcactattcc agaatgggta aaagaaacag tatggtatca aatttttccc
    34141 gaaagatttg caaacgggga caaagcaaat gaccccgaac acactttacc ttggggaagt
    34201 aaagatccag accgagaaga ctttttcggg ggagatttgc aaggtgtgat ggatcatttg
    34261 gattacttga cggaccttgg catcaatggc atctattttt gtcccatatt taaagccaca
    34321 tccaatcata aatacgatac gattgattat tatgaggtgg atcccgcttt tggcgataaa
    34381 aaacttttaa aaaacttgat tgatgaagca cataaaagag ggatacgtat catgttcgat
    34441 gctgtattca atcatatggg tgtccattca ccacagtggc aagacgttct caaaaacgga
    34501 gaaaaatcga tctataaaga ctggttccac atccgttttt tcccagtaga ttcttatcag
    34561 atgactgact taccagaaac tgctgaaaat atcccatatg atacttttgc ttttactcca
    34621 ttcatgccga aactaaatac agcaaatcca gaagtgcaaa aatatttgct ggatatcgca
    34681 acttattgga taaaagaatt cgatattgat ggatggcgtc ttgatgttgc taatgaagtc
    34741 gatcatcatt tttggaaaaa attcagagaa gcagttacag aaatcaaacc agacatctat
    34801 atccttggag agatttggca ttcctctcaa gcttggctgc aaggggatga attccatgca
    34861 gtgatgaatt atgcatttac agattcgatt aaagattatt ttgcaaaaaa gaaaatcaca
    34921 gcttcacaaa tggtcagtgg aatgaatcat cagcaaatgc tttacagaga tcaggtgaac
    34981 gaaggaacat tcaacttatt agattctcat gatactgcca ggatcttgac cctttgccaa
    35041 ggtaacaaag aattgatgaa gtctgtgatg gcctttatgt ttcttcaaaa agggtctcct
    35101 tgtatctatt acgggacaga aatagggatg actggtgaag atgacccgga ttgccgcaaa
    35161 tgtatgatat gggagaagga ggaacaagat ctagagctat tcggttttat aaaagaactt
    35221 gtttctctaa ggaaacagtt gtctaagatt atttctgaag gttctactca gtggctaata
    35281 gtaaatgatc gtgaagataa gctctatttc acacggaaac tagagggaca gatcatctat
    35341 gtttacttta atcagtcaaa agaaccttgg gtagtagaac aggaaaatga ggtgattctt
    35401 agtcaaaatt gtcagttgtt agaagacggg aaagcagaga tacgacaata cggatttttg
    35461 atcatgtgtt gaaaactgtt accggtaaca acaagaaagc gtttgcaaat gaagatttgt
    35521 gcccattata ataagggtgt aacagcacgt tgaatacaaa ggaggaaatg aagatgaaaa
    35581 aaagaagtgt gaaacagttg ggtttagggt taatctcttt aggaatctta ggcggattag
    35641 cggcttgtgg caatggtaac tcttcagcag aaggggaagc cgatgaagga aaaacgttaa
    35701 cagtttccgt tgattctgga tataaagatt atataaacga aataaaaaac actttcgaaa
    35761 aagaaaacga tgtgaaaatc aagctagtag aaaaggacat gttcgatcag ttggaatcat
    35821 tagcgttaga tgggcctgct ggaaagggac ctgacgttat gatggcagca tatgaccgga
    35881 tcggtgcgtt aggacagcaa ggacatctgg cggaagtaaa actgggaaat gaagcagctt
    35941 acgatgaaac agacaaagcc caagtgactt atgatggaaa aatctacgga gaacctgcag
    36001 taatcgagac ccttgttttg tactataaca aagatttagt cgatacagca ccatcaacgt
    36061 ttaaagattt ggagaatcta tccaaagaca gtcgttttgc ttttgagtca gaagcaggaa
    36121 aaaatacagg atttttagct aaatggactg acttttatta ttcctatggt ttaattgcag
    36181 gttacggtgg ctatgtattt ggtgatgatg gcacaaatcc ttcagatatc ggtttgaata
    36241 atgcaggtgc tgtagaagga atctcttatg caacagattg gttcaaaaat gtttggccaa
    36301 agggaatgca agacataaaa agtgcaggag acttcgccag ccagcaattc atgtccaata
    36361 aaactgcagc aatcattgac ggtccatggc aagcgcaaac atacaaagaa aacaatatca
    36421 attatggtgt agccaaaatt cctactctaa ataatggaca gccttatcaa ccgtttggcg
    36481 gaggaaaagg atgggtagtc agcaattatg ctaaaaacaa agacctctct caaaaatggc
    36541 ttgattatgt aacgaatcag gaaaatcaag aaaagttctt tgaaatggta aatgaaatcc
    36601 ctgcaaacca acaagctagg gaaacagcaa aggctaaaaa cgatgaatta acaacagctg
    36661 tgattgaaca atatgaaaca gctcaagcga tgccaaacat cccagaaatg ggcgaagttt
    36721 ggacaggtgc agaaaacttg atgttcgatg cagcatcagg ttcaaaaaca ccaaaagaat
    36781 ccgcagatga agcagtaaaa acaatcagtg aagccataga acaaaaatac tgattaaaat
    36841 gataaccgtc catttttata aaaaatggaa caggtgcttc agataaaagt ggcaagagcg
    36901 agatggaaaa ttatcttgct cttgttgcca ttatcttaaa agcagtttgc ggtttagcaa
    36961 gtttagaggg ggcattcaga tgcagcaaga taaaacaagc aatatcaacg aaaaaaaaat
    37021 cacgctttgt tcacttattc cagggatggg gcagtttgta aatggccaag cttttaaagg
    37081 tatcgttttt ttcgccatat tcgtcctatt cattggtcag atgcttctgg gcggatttca
    37141 tgcattggta ggattggtta ctttgggaag tataccaatg gaagatcatt cattatttat
    37201 tttgattgaa ggcactttgc aattcatcat tacaatcatt ttcttgattt tttacggttt
    37261 gaatctttta gacgcttatc gagtagcgaa gatgcgtcaa gagggcaaaa aaatcaatcg
    37321 gacgatgaag gaagtcatac ataatatagg tgatgaaggt tttccttatc tattgacact
    37381 tcccgcttat cttctcatga tttttacgat cattttccca gtcctagtta cattgttcac
    37441 tgcatttact aattatgact tcaatcatat tccaccagcc agtttaattg attgggtagg
    37501 ggctaaaaac ttttttagta tcttcttttt aagctcatat cgtaatactt tttttgcagt
    37561 cttttcgtgg accgtgattt ggactttatg tgcaacaact ttgcaaatca cccttggtat
    37621 tctcacagcg gttgttgctc accagaaatt tattaaattc aaacgtattt tcggtatcat
    37681 tttcttatta ccatgggcgg tcccagcttt tattactatc atgagttttt cgaatatatt
    37741 caacgatagc gtaggtgcca tcaatactca agtgattcct ttcataaacc agcttccttt
    37801 tgtagatatc agtgcaatct cttggaaaac ggacccgaac tggacgaaag tagcaattat
    37861 cttagtgcag ggctggttag gatttcccta tatctatgtg atggttacag gaatcttaca
    37921 atcgatttca gaagacttat atgaagcagc aaaaatcgac ggagcaaatg catggcagcg
    37981 cttttcaaac atcacgcttc ctgctgtctt cctagtggca gcgccaacat ttattacaca
    38041 gtatacgggg aatttcaata atttctccat gatctatctg tttaacaatg gcggtcccgg
    38101 aagcgtaggc ggaggagctg gttctactga tattcttatt tcctggatct ataaacttac
    38161 gactggaact tctccgcagt attctatggc ttcagcaatc acgttgatta tctccgtcat
    38221 cgttatctgt gtgtcattgc tggtatttaa aaagacaaat gcgttcaata tgggggatta
    38281 acaatgaaaa aatttcattc gagtgctcga ttccaaaaac gactttctca cttttttact
    38341 tacttttttc ttttaatact gtcagtcatt atcatctatc cgcttttgat cacagcaagt
    38401 actgccttca agtcaggaaa tattgcagct tttagtttag atctttcaag tgactggact
    38461 ttaggaaact ttactcggct attcagtgaa acactttacg ggacttggta taaaaataca
    38521 ttgatcattt ctgtcctaac aatgatcgta caagtgactg tagtaacttt ggcgggctat
    38581 acttatagtc gctatcgttt tatcggccgc aaatcaagtt tgatgttctt tttagtgatt
    38641 cagatggtac cgactatggc agcattgact gccttttatg tcatggcttt cttattagaa
    38701 gcgctcgata agtactggtt cttgacaatg atctatatag gcggtggaat tccaatgaat
    38761 acttggctga tgaaaggata ctttgacact gtaccaatag atttagatga atctgctaaa
    38821 cttgatgggg cagggcattt caggattttt ttccagattg tattaccgct tgtcaaaccg
    38881 atgctcgccg ttcaagcatt atgggctttt atgggacctt ttggggattt catgttagct
    38941 aagttcctgc ttcgaacacc tgaaaatcag actgttgctg tcggcttaca aacatttatt
    39001 tctgatgtga caaaccaaag agtctctctt tttgctgctg gggcaatttt gattgcacta
    39061 ccgatttgtc tattattctt ctttttacaa aagaactttg ttaccggcct gacatctggc
    39121 ggaacaaaag gataggagca gagtatcatg caaacatttc cgttaaacta tttttccgca
    39181 ttacgtacgc caactcaagt gtttgcggga cgcaaactat tatcatggcc taaatttttc
    39241 ttgatatttg tatttttagt ttccttgatg gtcatgcctg tgactctttt ttatgccaat
    39301 cagatccaag cgattccatt agaacaattt ctatccgttc attcgctgat cgatgaacaa
    39361 ggaacccaaa aattttctga acttgaatta tctgaaactg ggttacaagc atcgcaacaa
    39421 acgatagctg tgacccctga aattttggta ggtgtgtctt tatctgagaa acaacaatcc
    39481 gatcatggaa cttttattga ttttgagaag gaacaatggg tgatccaaca aaaggataaa
    39541 tctggtatac gccgctatac gatgaattat agcccatctt tccaaccaga ttctgtacgt
    39601 acgcccgaag atttccaacg atttttagaa agagaatttt atgccagtaa tcgtccaaca
    39661 atcattttat cttatagttt aagtcttggt cttgtcctat ttgtcatgac gagtctcatt
    39721 ttattcgggg cttccttttt cttgtggatg acaagaaaaa gccaactttc atccattcat
    39781 acattcaaag agagtgcaaa tttgatgctg aatgttatgg gaataggttc catggcagca
    39841 gcagttgtag ggtttatcca ctttgacttt atcttgatgc taagtgtcca aacaacgata
    39901 actgtcttgc tgcttttatg ggtttttgtc aaaacaagat tcaaagataa gcgtgtcgaa
    39961 tgacaagttt aagcgattta tgcgacaatg aatgtgaaaa aaatgaaaaa taaagtagtt
    40021 tttgaaaaat ttctgaaaaa attaaacttc ttagttgatt cttttctttt ttagtattaa
    40081 cgtaataggg tagttttttt aaggaggaaa atcatgttag agaaaacttt atacaatcaa
    40141 ttattttcac gttctttctc gctccctgtc gaagtaaatt attgggacgg tacaacgaaa
    40201 caatacggag atacggacac tcctccccaa atcaaaatca atatccatga agaaatccca
    40261 atgaaagaga ttacaagtaa cgcatctttg gcactaggag aagcctatat ggatcatcga
    40321 atcgagatcg agggaagtat ccaagcattg atcaacgatg cttatcagca agcaaacagc
    40381 tttttacgag gaaaagatta tctaaaatgg ctgccaaaga aagaaaaaca tacgaaacaa
    40441 aaaaacaaag aagatatcca tgcgcattat gacttaggta acgactttta taaactttgg
    40501 ctagatccaa ctttgactta ttcttgtgct tatttcaata cacctgaaga tacgttggaa
    40561 caagcacaaa tcaataaagt ccatcatatc ttagacaaac tctttatcaa agaaggcgaa
    40621 acgttgcttg atatcggttg tggctgggga acattgatgt tcactgctac caaagagtat
    40681 aatgtcaagg caactgggat cacactaagt gaagaacaat acgatttgat taccaaaaga
    40741 ataaaagaag aacatttaga agataaatgc cgtgtattat taatggatta ccgcgaacta
    40801 aaaggcgaaa cgtttgatca tatcacaagt gtaggtatgt tcgaacatgt aggttctgaa
    40861 aatcttgaag gttatttcaa agtggtaaaa gatttattga aaccaaaagg aacagctttg
    40921 atccatggaa tcagccgaca acaaggcggt gcgacaaatg cttggatcaa taaatatatt
    40981 ttccctggcg gttatgtccc tggtgttact gaattagttg ataatattac aaaaaacgat
    41041 ttgcaactga ttgatttgga aagcttacgt cgtgactacc aattgacatt agaacattgg
    41101 acaaagaatt ttcatcaagt ccaagatcaa gtcacgaaag aaatgggtga ttccttctat
    41161 cgaatgtggg atctatattt acaagcttgt gcagcttcat ttgaatcaag taatatcgat
    41221 gtgattcaat atttgcttgt tcaacctgga aacaatgaca tcccaatgca tcgtgcataa
    41281 ttgaggcaaa agtactgttt aaagactatt taaaaagaag ctaagtttta tgatgctcca
    41341 gaagtgaact tttttgtcta acttctagga ttgtctctaa agcttagttt ctt
//
LOCUS       DAFBSV010000012        41266 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.012, whole genome shotgun sequence.
ACCESSION   DAFBSV010000012 DAFBSV010000000
VERSION     DAFBSV010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.012"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            214..498
                     /locus_tag="LLB18_000671"
     CDS             214..498
                     /locus_tag="LLB18_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HBK5243694.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(779..1198)
                     /locus_tag="LLB18_000672"
     CDS             complement(779..1198)
                     /locus_tag="LLB18_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HBK5243695.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(1200..1784)
                     /locus_tag="LLB18_000673"
     CDS             complement(1200..1784)
                     /locus_tag="LLB18_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HBK5243696.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(1831..3306)
                     /locus_tag="LLB18_000674"
     CDS             complement(1831..3306)
                     /locus_tag="LLB18_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBK5243697.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPTMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            3487..3798
                     /locus_tag="LLB18_000675"
     CDS             3487..3798
                     /locus_tag="LLB18_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243698.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(3913..6249)
                     /locus_tag="LLB18_000676"
     CDS             complement(3913..6249)
                     /locus_tag="LLB18_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK5243699.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            6391..7059
                     /locus_tag="LLB18_000677"
     CDS             6391..7059
                     /locus_tag="LLB18_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5243700.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            7062..8105
                     /locus_tag="LLB18_000678"
     CDS             7062..8105
                     /locus_tag="LLB18_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK5243701.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(8342..9223)
                     /locus_tag="LLB18_000679"
     CDS             complement(8342..9223)
                     /locus_tag="LLB18_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK5243702.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            9382..10110
                     /locus_tag="LLB18_000680"
     CDS             9382..10110
                     /locus_tag="LLB18_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBK5243703.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            10266..10583
                     /locus_tag="LLB18_000681"
     CDS             10266..10583
                     /locus_tag="LLB18_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBK5243704.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            10576..11184
                     /locus_tag="LLB18_000682"
     CDS             10576..11184
                     /locus_tag="LLB18_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBK5243705.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLVWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            11239..12030
                     /locus_tag="LLB18_000683"
     CDS             11239..12030
                     /locus_tag="LLB18_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBK5243706.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            12168..12656
                     /locus_tag="LLB18_000684"
     CDS             12168..12656
                     /locus_tag="LLB18_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBK5243707.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            12707..13579
                     /locus_tag="LLB18_000685"
     CDS             12707..13579
                     /locus_tag="LLB18_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBK5243708.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            13755..14117
                     /locus_tag="LLB18_000686"
     CDS             13755..14117
                     /locus_tag="LLB18_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBK5243709.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            14126..14878
                     /locus_tag="LLB18_000687"
     CDS             14126..14878
                     /locus_tag="LLB18_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5243710.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            14892..16694
                     /locus_tag="LLB18_000688"
     CDS             14892..16694
                     /locus_tag="LLB18_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5243711.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            16971..18011
                     /locus_tag="LLB18_000689"
     CDS             16971..18011
                     /locus_tag="LLB18_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBK5243712.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(18063..20207)
                     /locus_tag="LLB18_000690"
     CDS             complement(18063..20207)
                     /locus_tag="LLB18_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBK5243713.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(20564..21937)
                     /locus_tag="LLB18_000691"
     CDS             complement(20564..21937)
                     /locus_tag="LLB18_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK5243714.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="LLB18_000692"
     CDS             complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="LLB18_000692"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HBK5243715.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="LLB18_000693"
     CDS             complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="LLB18_000693"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBK5243716.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(23385..24398)
                     /locus_tag="LLB18_000694"
     CDS             complement(23385..24398)
                     /locus_tag="LLB18_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBK5243717.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(24479..25078)
                     /locus_tag="LLB18_000695"
     CDS             complement(24479..25078)
                     /locus_tag="LLB18_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBK5243718.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            25264..25965
                     /locus_tag="LLB18_000696"
     CDS             25264..25965
                     /locus_tag="LLB18_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5243719.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            25975..28686
                     /locus_tag="LLB18_000697"
     CDS             25975..28686
                     /locus_tag="LLB18_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5243720.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGTIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            29137..30765
                     /gene="treC"
                     /locus_tag="LLB18_000698"
     CDS             29137..30765
                     /gene="treC"
                     /locus_tag="LLB18_000698"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBK5243721.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(30825..32006)
                     /locus_tag="LLB18_000699"
     CDS             complement(30825..32006)
                     /locus_tag="LLB18_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBK5243722.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            32258..33781
                     /locus_tag="LLB18_000700"
     CDS             32258..33781
                     /locus_tag="LLB18_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBK5243723.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(33850..34578)
                     /locus_tag="LLB18_000701"
     CDS             complement(33850..34578)
                     /locus_tag="LLB18_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5243724.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(34591..35871)
                     /locus_tag="LLB18_000702"
     CDS             complement(34591..35871)
                     /locus_tag="LLB18_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBK5243725.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(36012..36614)
                     /locus_tag="LLB18_000703"
     CDS             complement(36012..36614)
                     /locus_tag="LLB18_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBK5243726.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            36859..37065
                     /locus_tag="LLB18_000704"
     CDS             36859..37065
                     /locus_tag="LLB18_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243727.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            37377..38096
                     /locus_tag="LLB18_000705"
     CDS             37377..38096
                     /locus_tag="LLB18_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBK5243728.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(38177..38860)
                     /locus_tag="LLB18_000706"
     CDS             complement(38177..38860)
                     /locus_tag="LLB18_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBK5243729.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            39078..41264
                     /locus_tag="LLB18_000707"
     CDS             39078..41264
                     /locus_tag="LLB18_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBK5243730.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNISVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT        13384 a         7322 c         8275 g        12285 t
ORIGIN      
        1 aggaagaggt tgtgagcctg ccgtttaact ctgagtcaca aggagcaatt tcaaaaaaca
       61 gcttctcatg tttgttgact attgtgactt gtgaccgagg agttggcagg agaacaccgt
      121 ttattcgaaa aaaggaactg cgacaagact tttgtcacag ttccttcttt tttttgctat
      181 gctatactag atgtaaaaaa taggagaaat aaaatgaggg aaatttattc ttttgaatca
      241 aaaatctatg cttccgaagt cggcaagggc ggggcatata ttatttttcc gtatgatata
      301 agaaaagaat tcggtgctgg aagagttaaa gtccaagcaa cttttgacaa tgtgccatat
      361 gaaggcagta tcgtgaatat gggcgtgaaa aatccagatg gttcagtctg ctacatcctt
      421 ggactacgaa aagatattcg taaaaacatc ggaaaagaaa tcggtgatat tgtagcagtt
      481 acagtgaagc aaaaataaaa gaggttgtga caaaagacgt gtcacaacct cttgataaac
      541 ggtgttcaaa agccagtttc tcggtagtaa gtcaaattta tgcaaaaatg tggaaaccca
      601 tgtttacaaa atttttctta ctactcgaaa cgaagcggct ttatcacaac ctcttgataa
      661 acggcgttca atcagctgtc cctcggtatt agctcaaaaa cggcaaaata tgagaagcta
      721 tttttccatt tttttctctc atactcaggt cataacgctg atttcacaac ctcttctttc
      781 ataatggttt ttcaccatct ttataataaa ctggttcttt gatatggaaa tctatttttt
      841 ccaaccaatc taaaatcttg taacctaact cttctgacat cggaaaagag gcgttgattt
      901 gtgcattgga gatatggtca acatggatac cggaagtgat cgtacaactt cccggaacgg
      961 cagttttgat gatcacagct attttttcgg ctaagacatc gtctttatgg aaccgaccat
     1021 cgtggctagg gaaacgtaca gtttgcatct ctgtatcacg agaaaatgta gtgactgttc
     1081 cgatatgtgg tgtatctccg cctgttaaag tgatcaataa gtctttaccg attactttaa
     1141 cagcagcttg gatcgtgaaa cctagtttgg ttacttcaac tatcgtttct ttttccatat
     1201 taatcaccct gccaacgttt tgaatgctca tttacaattt caaattgatc caaaagtttc
     1261 attgtatggt gattaacaag atcttggatc gtttgaggct gattataaaa agcaggaatt
     1321 ggtggtatga tttgcacacc tagtcgtgct aatttagtca agttttccaa gtgaatggca
     1381 tttaatggcg tttcacgagg aacaatgact aactttcgtt gctccttcat tgttacatca
     1441 gcagcacgtg caatcaggtt gtcgcctaaa ccaacagaga tacctgcgac tgttttcatg
     1501 cttgccggta cgatgatcat tccatcggtc aaaaatgatc cgctggcgac agcagcacct
     1561 aaatctttgt ttgaataatg gtaatcaaac aggctttcga attcagttag tgataagtcg
     1621 gattccagct ttaagttctg ttttgcccat ggactgatga ttccgtgtgt ttctatcatc
     1681 ggatattctt ttagtttctt cactaggttg atggcataaa tggtgcctga agcgccactt
     1741 acaccaatca cgattttttt cttccgttgt gccaattgtt ccattttccg cactcctttt
     1801 tatgatgtca aaacagttgc agatcattca ttatttcaaa tatttttccc aatcttctac
     1861 ttcttggaat tttgcacgta caaaatgttc tttcatatcg aaaggaactg taccgtcaaa
     1921 gatagttttt gcacttatcc cacggaaacg aatagagcca ggattatatt ctggtaattc
     1981 tgatgggtcc aatggatggt tcctcattcc tgggatcacg atgatatctt tatctccttg
     2041 gaaacgagtg ttgaaagtcc aaactacatc gttcatgtcg aaaatatcaa catcttcatc
     2101 gactaaaatg actgtcttca attctttgaa ggctgataaa gcaagaatag ctgcttgacg
     2161 ctgaatacct tcatccgctt cgttttcttt acggatttgc atgatggtca tcaatttacc
     2221 accacctgca ggaggattgt agacatttac tacttttcct ggaatagctt tatcgaccaa
     2281 ggcaagaata cttgcttctg taggaatacc ggccatagat acgtgttctt cactgggacc
     2341 aatcgttgtt tgcatgattg gattgtcttt tcggtgagta actgctttga ctttcactac
     2401 ttgtacagct ggattagcat ccccagtata gccaggaaat tctggcattg cttttcctga
     2461 gttcgtgttg atatcttctt gcattgtttc atttggcatg atttctgctt caatgatgaa
     2521 ttcagcacga gcaataccca cttcatcgac tgctatacca tcaacgattt gaataggttc
     2581 gttacgcaaa gctcctgcac accatagttc attgtagcca agtggagtgg taggtggttc
     2641 gaaagtcgtg ccaatggcaa ttgctggatc taaaccaata ttgatagtga taggcattgg
     2701 tttattcaag gcttcgaatt gtttttggaa gtgaccaatg tggcgtccgc caggcatgat
     2761 gtacataccg atcgtatctt tatcttctag aaccatacga tggatcgtta catcgctcat
     2821 tgttttttct ggatctgatc ctaagactac acccattgtg atgtatggac cagcatcttc
     2881 aggagtattt gtaggtgcag gcaaaatgtt gcgaatatcg aagtctgcat cggtagctag
     2941 atgaacgact tcttgtgctg gagcgtctgc tttgtctact ttcacaggtt tgattggatt
     3001 ttctacagcg tctttcaaga aacgaccaag tgttcgataa tcatggtgca aaatttcacc
     3061 tacacgttta cgactagcca ttgttccgat gttcacacgt gtgccgggga aacctttgat
     3121 attgttgaaa gtcatagttg gtccttcttg agtcggacgt tttactgtac cgccagcacc
     3181 gatataacgg taaacaccag ataattctgc ttcaggatcg atttcaatat ctgtttcgtg
     3241 atattgacct ggaagtgttt ttagttcttc gatgactttt cttaaatcat acggttgatc
     3301 tgtcatgaga gattcctcct tagttgtctt tacctatcta tagtaaaagg tgaaaaagag
     3361 gaaaacaatt caacttgttc ggtaaagtat tctacaatgg aatggatgcg tttttttgat
     3421 aatagaataa actatgatat acttatcact aaaagaaagc gcatacttag tgttggagga
     3481 aggaaagtga aaaaaatgga ggagtcattt cctaaagcag taaaagtgga aaatatagcg
     3541 aatattttga aagttacatt tgaaaacgga gaagtaaaat acgtgaaatc tcattggaca
     3601 gaagagataa ccgatgcctt gcaatttgga aaaaaaggaa gaggaaaaag aaaaaatctt
     3661 ctcgcacttt ctcgtaatat gtggattggg actgaagtaa cgattgaagc agatggaaca
     3721 gtattcataa atggaaaaga caggtatacg ccagaagagt tgtggtacaa aggaaagaaa
     3781 agtataccag aattataaaa aataattaaa aaaaacagcg cgaaacaagg aacatattac
     3841 ttcctcgttt cttgctgttt tctactattt cagcgctctt atgactcaaa tctaaatgtg
     3901 gttgtcacaa ccttattctg cacgcaaagc gatagcggcg tcttttttcg ctgccattcg
     3961 tgcaggaaga tgaccgccaa gcatcgtcaa tatagtagag acgatcacta gaataatcgc
     4021 atggacagga tttagttgag caacattttt tagatccgtc atgttgtata agatgctatt
     4081 gatagggaac gtagctagcc atgcaataaa cacacctaat atcccagaag aaatacctaa
     4141 aatacacgtt tctgcgtcaa atacgcgagt gatgtctttt ttacgtgcac ctaaagcttt
     4201 tagtacaccg atttcttttg tccgttcaat cacagatgta taagtaatga tactgatcat
     4261 gatcatactt gttactaaag agatccctgc aaaagcaata aggacataag tgatagcatc
     4321 catcaatccg ccagtcagtt cagtcatcgt tccagctaaa tcagtataaa tgattttatc
     4381 ttcatctgat ttgcctttat tgtaatcatc tagataatcc aagatctttt ctttgtcttc
     4441 aaaattgttc ggataaatca tgatacttga aggcaagctg tctccaccta aataactaag
     4501 caatgtttgt ttggcatttt cgtcaacttt ttcagtagtt aagacattta caccactgtc
     4561 tctttgagct ttgacgattt ctgattcttt gttttcgttg acgatttgag tcgttaattg
     4621 atcgctataa gcgattcctg gagataagag attcattgta gaagaagatt tcacgcgtag
     4681 gatccccgag atcttcaatt catcagaagc attctgatac atcgcatcat aatctgtatt
     4741 agggataaaa ttcccagttg gaagttttgt atagtaagta ttgttgttta ctaatttgaa
     4801 tgttgtacca acgatatcat caaaatcaag tttttcgtct tctttcacat caaatccaag
     4861 attcttcaat gcgttgatat tagtattatt attgccgtct acgatcagca cgacatctgt
     4921 tgctgaggct ggataacttc cggcaagtaa agaataattg tcttttaaaa agttttcttt
     4981 gctagtgtca agctgtgtag ggaaacttga cactcccaca cctgtcattg ctgacatcgt
     5041 actagataaa gaaagagatt ccgtatcagg attttgattc gagaagctga caggctgtac
     5101 tttgccattt acatcacgta aaagattgat tcctgtagta cgggtaaatc cgatattatt
     5161 acttaagtta ggatcgatgt ctgttacgta atcgacgtat gtttgatcaa tcttattcgt
     5221 gtgctgtgct ttatcttctt cgctgacttt tgcagtaatc gttttgctgt ctggataatc
     5281 cgctttgctt gcacccaatc cggcatcgtc acgagtctgg ttagtcgtta ccttagaaat
     5341 agtaatcgga aatttcgcca tcgtttcagc ttgcgtgtta tcgatttgtt tttggaatcc
     5401 agaagaaagg gacagaacga tcgcgattcc gatgatccca atactggaag caaaggaggt
     5461 caagaaagta cgtccttttt ttgttcggat attgttgaag gaaagcttta acgctgtcca
     5521 aaaactcatc tttgttctgc gtaagttaaa ttgatcatct tttggtcgtt cgatgtgagg
     5581 atgggaatct gttaagatct taccatcaga aaattcaatg attcgatctg cgtattgatg
     5641 ggccagttca ggattatgtg tgaccatgat cactaatttt tctttcgata actcttggat
     5701 caattccatg atctggatac ttgtttctgt atctaacgct ccggttggtt catcgcacaa
     5761 aaggatatct gggtcattgg ctagtgctcg agcgatggcc actcgctgca tttgtccacc
     5821 agataactga tttggctttt tatgcatatg atttgtcaag ccgactcggt gcaatgcatc
     5881 ttctgcccgt tttcgttttt cgtctttaga aacaccactt aatgtcatcc caagttcaac
     5941 gttttcaata atgcctagat gaccaatcaa gttgtaactt tgaaaaatga aaccgataga
     6001 gttgtttcgg taggcatccc agtcactgtc cttaaagtct ttagtagact ttccgttgat
     6061 taccatatca ccggaatcat aattatctag tccaccaatc acattcagca tagtcgtttt
     6121 accagaacca ctaggaccta aaatcgctac gaattctttt tgtctgaaag cgacagacac
     6181 accatccaat gctttggtgg tggtttcgcc gactttataa tattttttta tatcttttaa
     6241 ttgaagcata atcacccttc tcccgtattg aaatattcgg tatactaata agtatatcag
     6301 aacaatgatc gtagtatacg aaataaatgt taactgaaga tgaactacaa gaaaaaatct
     6361 agaaattttt caaaaaacag agggagatca atgaatcgta ttttagtagt agaagatgat
     6421 ccgcaattac agttgcttta ccgttctgtg ttggaacgag cgggcttttc agtcatcacc
     6481 gcattgaatg gagaggatgc gctgaaaaaa ctagaagcga cacgtataga attaatcatt
     6541 acagatatca tgatgccgaa aatggatggc tatgacttgc tagactcatt acgtagcacc
     6601 agatttgaca cacctgttct aatgattacg gcaaaggccg attttgagga taagaaacgc
     6661 gggttcaaat taggagcaga tgattatatg acaaaaccca tcgatgtcaa tgagatgatc
     6721 ctacgtgtgg aagcattgct tcgacgttca aagatcaatt acagcagtag cttgataatc
     6781 ggacaaacaa aattagagct agatgcttat acagtgttac aagatcagca ttcgttgatt
     6841 ctgcctcaaa aagaatttct gcttctgtat aaattactgt cttatcccaa caagatcttc
     6901 actcgccaac agttgatgga tgatatttgg ggattagata cgaatacaga agaacgaacg
     6961 atcgatgtac atatcaaacg tttaaggacc cgttttgaaa agacggaaga ttttcaaatc
     7021 atcacagtac ggggactagg ctataaggcg gttatttaaa gatgaaaaaa aagctatttt
     7081 cacaattatg gatctatttt gctagtattg tcttcatttc gatcttagtg acactgctgt
     7141 gttttctcgg ttttattttc ttattgtctc gacattctat ctcgcctgct gaatcggctg
     7201 gaaaaccaac gttatacccg ttattcgtct ttgcggggtt cagtatggtc gtgggtacag
     7261 gaatatcgat ttttgttggg cggcgtatcc tgcatccaat cagtgcgcta gggacaaata
     7321 tgagtctggt agcaacggga gatttttcga ttcgaatgga tgaacagcag aaagtagcag
     7381 aagtacagca actgtataaa gatttcaacg ttatggtcca agaactcaat agtatcgaga
     7441 cactgaggaa tgactttgtg tccagtgtat cccatgaatt caaaacacca ctagcaacaa
     7501 tccaaggata tgttcaattg ttacaagccc caaatctctc tgacgaagaa cgccaaatat
     7561 ttttatatcg gattatcgaa agtatcacgc agctttcaca attaacagag aacatcttaa
     7621 aattgaacaa actggaaaac cagcgtatcc aactggaaaa gaaagagtat cgattagatg
     7681 aacaaatcag agaagtaatc gttttttttc agcctaaatg ggagaaagaa cagctagaat
     7741 tggatatcga acttgctgca gtaaattaca caggcaatga agagtttttg taccaagtgt
     7801 ggctgaatat catggataac gccataaagt acaatcaaat caatggacag attcatatca
     7861 aactatttga gacagccaca gagattgtac tggaagtgac cgattcaggt gtaggaatga
     7921 atgaagagac cagagatcga atgtttgaaa aattttatca aggagataca agtcgtcaaa
     7981 tttctgggaa tgggctagga ctttcactgg ttaaaaaaat tctagaactg catgatggac
     8041 gtattgatta tagcagtatc gaaggagtag gaacgacagc aatgatacgg ttaagtaaac
     8101 aataggaaaa agaataaaac ccctaaaaat tctattgaag gtttttaggg gtttttagtc
     8161 gtttttttgt gattagggaa atgttcttac ggttcttttg gcataaaaat cgctgctttc
     8221 ttattgaact acgagaaatg ttagaggtgt cattgaaaca aggacatgat gcaagaaaga
     8281 gagcgaaagt catgcgtcgc tctctttttt tgggtggata gatggacaga aaatgtaggg
     8341 cttagttttc ttcttgattt aaatactccc aaaatgtatc tgaagccaaa gaatgctcac
     8401 cgactttacg agtaaatgca agataactct ctgttgttgg agaaataggg agaatcacag
     8461 tattttcttt taatagattc ttgactgttt tttccataac aatagcaatc cccatgtcat
     8521 ttgcaatcat attgatgatc aagtcgattc ttgctccttt ataagagatt tttggttcaa
     8581 atccagcttc gcgacacaga tctagtacag gttgatacaa gttcgtagtg gggccaagga
     8641 gcaaaaagtt ctcctttttc agttcgctta gatccaattt ctttttacta gctaaaggat
     8701 gatttttagg tagaactgct acaaaatcgt ctgtttcagt aggcaaccac tcaatcgaac
     8761 ttggtggggc ctggaaactt ctagcaaagt ggatcgtgtc actatgttca ttggcgtcat
     8821 tgtaagttaa ttcgacactt tccacttctt tcaactggac tgtaaattca ggatggcgtt
     8881 tcaaaaactc ggtgattttg gaaaaacctt tataattgat cattgtcggt atcgttaaga
     8941 tatttaatga aagattgttg tctttcgtat aggtttcaag cacttcttgc atagcatggt
     9001 attgttctac gacatttttt acatatggga gcaataagct tccagcttcg gtcaattcga
     9061 tttttctatg ggcgcgttcg aataatttga cgtctaattc tgtttctaac gaaagaatct
     9121 gtttagaaat atttccttgg gtggtgaatt gtcgatcagc agttttggtg aaattcattg
     9181 tttcggctaa atcaagaaaa acttcgaatt tatggatatc catcatattc ctcctactta
     9241 ttccaataaa gaatacttta acacaaaaaa tgaattggtg taatcttctc tgtctgttac
     9301 aatctttctt gcagcgaaag caataattac agaaattttt ctgatttttt tcgcttcgta
     9361 gaaaaagaga ggagtttttt gatgccaact ggagttttga tcaatgtagg ttccgttttg
     9421 tttggcggac taattggcgg attagtagga aataaattaa gtgaacattt taaagcacag
     9481 ctgacgatgg tttttggtgt gtgttcgatg gggatgggaa tctattccat tgcgccgatg
     9541 aaaaatatgc cggctgttat ttttgcttta gtgataggaa cagcgattgg tttgattgtt
     9601 catttaggta atgggataaa taagggggct gcgctgatgc aagtacctat ttctaaaatc
     9661 ttccctagtg aaaagcttgg tatgacccac gatgaattta tcagcacatt agtgacggtc
     9721 attgttctat tttgtgcaag tggtacgggg atctatggaa gtttagattc tgggatgaca
     9781 ggagacagta cgattttgat ttctaaatct gtccttgatt ttttcacagc agctattttt
     9841 gcgtgtaatt tagggtatgt cgtttctgtg atagcaattc cccaattcat tattttttat
     9901 attttgttct tattggcaaa atttatttat ccattgacta caccagacat gatcttagat
     9961 tttaaagctt gcggcggatt cttgatggtc gctaccggtt ttagaatgat caacgtgaaa
    10021 atgttcccag tagctgacat gatacctgca atgatcgtta tcatgccact gagctggatg
    10081 tggacaaatt ggattatgcc actgttataa taaaaatcaa agagaagcca ttttttgctg
    10141 actaaaaagg atcaaatctt ttagtcagtt tttttgtatt tgacaaactg attttgaaac
    10201 tatattatat gttgtataat atagattgaa ataaaatatt acacttgaga atagaaggtg
    10261 acgtaatgca catccagatt ccaactgttc ttcttgatgg tactgtgcta gcagcattaa
    10321 gcaaggaaga tatgtatggg tatgccttaa caaaaatcgt acaagaaagt ctctctgtca
    10381 gtgaatctac actatatccg gttttgagaa gattgaaaaa agaaggatat cttgagacct
    10441 atgatgaacc ttttgaaggc agaaaccgtc gatattactc gttgacacca atgggaagtc
    10501 gtcatttaga agaaattatt gatgaatgga ttgtttttcg agattcttta gaccggttat
    10561 tggaggagag cacaaatgaa tgaatatttg aatgaagttg tggatcatct tcaagaaatt
    10621 cctgaagacg atcgttttga tttgatccag tattatgagg aatatttttt agattctgga
    10681 aaaacattag atcagatcat tgatgaatat ggtacaccaa agcagtttgc cttaaaatta
    10741 aaaatcagtt acttttcaga agaagaacaa gcagaaaacg agttagtgaa aaatccaaaa
    10801 agacaaattc gcctggtttg gttaatcatt atcggtttat ttgcttctcc tgtcctcatt
    10861 ccactagcac tggggtttat attggttatt gggggactat tggttgcttt actagcgctc
    10921 atttttagta tctatgtttt atgtatcagt atcttaggtg ttggcctatt catgatcatc
    10981 tcaggaatca gtgtgtttgg acaatcgatt ctgagtggat tattctttat cggtgtcggt
    11041 ctgttcgcca caggaagcgc agtatttatt tcgccactgt tgctgaaagg aacaaaaggg
    11101 cttttttatg tcatgatgaa ctttgttaaa tggatgggac gacgttttat tacaaaaaga
    11161 gatctgcatt cagcgggcgt ttgaaggagg acacataaat tgagattgaa acattttttg
    11221 attaccggta ttggtctgat gcttactggt ggcctcctag caggtgcaac ttatacatta
    11281 ggcgctcaaa agagtctgac ttgggataat ggtcctcggt tgatcgatat ggttactgag
    11341 acaaaaaaaa tcaaggatgc aaacaaaatc gtcatccatg cagaaaatca aacagtttcg
    11401 gtcatacgcg gattggattt tgagataaaa acgacttatg ataagacaga aaagccagaa
    11461 ataaaggaga aaaatggcgt gttgactgtg aatgcagtca aaaaatcaac aggtgcaatc
    11521 attagtttag aagacacaag tgcacaaatc actattgttg tccctgcaga tcatgaatta
    11581 tctgaattga caatcgaagg gaataatagt gcaattgata tcaacgaagt atcaatcaaa
    11641 aaagtgaata ctaagacaca tgatggctgg gtatcgttca atgaatttac aggaggaaca
    11701 ataactgcga aagatgaatt aggctcactt cgattagatg aggccaatgt ggataacttg
    11761 atcgtcacag gtgaaaacag caacttccat ctagaagaca gtttgatcag caaagaagga
    11821 aaagtcatcc taaacggtgg caatttatct ttgcatgaga tggaaaacag tggctatact
    11881 atccaaacgt ctggtgaatc ttatattgaa aaagactacc agccaataac aaatactttg
    11941 ttagaacaag gacagaaaaa gctaaagatc actgctaaag acacatcgat caatattacg
    12001 acggatcaag aggacaatga aacagattga tcctgtactc aactggatat tttaagaaaa
    12061 aacagcaaag atccttccaa tctttgctgt ttttcatcgc ttaacgcaca taactatagt
    12121 aaaataagaa agaaaatatc taaaaagaaa acagggtgaa agagtatatg aaggtagaag
    12181 aaggtcaaag agaaaagtta aaaacagaaa tggaaagatt acatacttat atcactcaac
    12241 taagccaaac cttctatgat ccagacaaag aaaaagtgat ggttaattac ccgaacaatt
    12301 cagaaggtcg ccaattagag caagtgtacc atgaagtttt caaacattta ttgacggtga
    12361 agaaagagct ggattattat tctttaccga ttatcgatac aggaatattg aagtatgatg
    12421 ggaagaagga acgatttatc tttaaatctg ttcgggaaga tttgcctctt tcagcaggga
    12481 tggatctaga ggtcttggta gaagactatt ttacagaaga aaagcactgg gttcgaacaa
    12541 aattggatta tttaccgcag gcagccggag ggacacaggc aagcggttgg tacatcactg
    12601 aagacaaaga gttagaacta gaaggtgtaa tggcgcgtat tcgaaaaaaa aattaaaaaa
    12661 gtaacattag atatttattg aaggataaag gagcgcagga agtagcatga gagaaaaaag
    12721 agcattttat atcaatggtt atgcagggat tgtcggattg gtcgtattag ctttagttgg
    12781 attgtttttc ttctatttag gtatgtggca agcgaaagtt tgggcacttt ttttaagtat
    12841 ttttctttgg ttgatcacgt tattgttgtt aagttcggca actgtagtca gtcctaatca
    12901 agcaaaagta attttgtttt ttggacaata tttaggtacg attcgagaaa atggcttttt
    12961 ccttacgata cctttggcac aaaaaatgac tgtttcgttg aaagttcgga atttcaatag
    13021 ttctgtttta aaagtcaatg atttggatgg aaaccccatc gaaatctcag cagtagtagt
    13081 ctttaaagtc gttgatacag caaaggcatt attcgatgta gcgtattatc aagattttgt
    13141 agaaatccaa agtgagacag ccattcggca tatcgctagc caatacccgt atgatacatt
    13201 caatgagaat gatttgacgc ttcgaggaaa cacgacggca gtgtctgacg agttgcaaaa
    13261 agagctgcaa gagcgtttag cagtagcagg tgtcgaagta atcgaaacac gcttgaacca
    13321 tttagcctat gcaacagaaa tcgctagtgc catgctccaa cgtcaacaag caaaagccat
    13381 tttgtctgct cgacaaacca ttgttgaagg agctgtcaca atcactcaaa tggccttaga
    13441 gcaaatcgaa gatggacaag aaatcaattt caccgatgat cggaaagtcc aattgatcaa
    13501 taatttactt gtctcaatca ttacagacaa aggaacgcaa cctgttatca atacaggcga
    13561 catgaaagac cgtaagtgac atactttttg taagatagga agaaggagtt taggacggat
    13621 tattgtcttg aactcttttt ttagttgttt taaagaaaat gacaaaattg aaagaagaat
    13681 gatagttgat tcgaaggcag aattgttcgc ttttttctat aatcagtata taaagtaaga
    13741 gagaagggga aaaagtgaaa aaacttctga tcggtctact tgttttcatc gttgtggtac
    13801 ttgcaggggt gaaaatcgca gattacgtag ttatgggtgg agaagaatac tatgtacaaa
    13861 ttacgacaga tggtacaaaa acagtttcaa aatcagactc tggacaagaa acagtcaact
    13921 atagatatat cctgcctggc tatacgaaag agggtaagga aaaagaactg gacttcaagg
    13981 gacaattgac tcgaccgctt cgtaaaggag catatttaaa aatcacctgg aacaaaaata
    14041 aaggtgtcac ttcgtatgaa gaagtcgaaa aaaaagacgt gccgaaaaca gcactggaaa
    14101 aactaattaa agggtaggga aagaaatgaa caaaatagtc gaagtacaga atgtaacaaa
    14161 agtatacgga aaaaacaatg agaaaaagac gcaagcatta agcggcatca gcttcgatgt
    14221 agaaaaaggc gaatttattg ggatcatggg cgcttctggt tctggtaagt cgacactttt
    14281 gaatatttta tccacattag ataaaccaac agatgggcat atccgaatca atcaaaaaga
    14341 tgtgaccaca ttaaaaggaa atcaactagc agattttcgt gcgaatgaga ttggctttat
    14401 tttccaagat ttcaatttat tagaaagctt gacagcacaa gaaaatatcg ctgttcctct
    14461 ttctttacaa ggcgtcagac caaaagaaat caagcaacgt gtccaaaaaa ttgcagaacg
    14521 tttatccatc tctcatattt tggaaagcta tccttctgag atttccggtg gacaaaaaca
    14581 acgggtcgcc gccgcacgtg cattgatcac acaaccaacg attctattag gggatgagcc
    14641 tacaggtgcg ctggattcca aaagtgcccg ggatctttta gatacgatgg acgaattgaa
    14701 tacaaaagat catgtatcga ttcttcttgt gacgcatgat ccgttttctg caagttattg
    14761 ccaacgtatt ttattcatca aggatggcgg tatccatcaa gaagtgaaac gtggagatca
    14821 aagccgtgat tccttctatc gagaaatact atctattctt ggaaacttgg aacagtaggg
    14881 ggagattgac tatgctttgg aaattatcac ttactgggat caagagccgt ttaagagact
    14941 acttggtgtt attctcagga ttagttatgg catctgctat tttttacatg tttgaatcaa
    15001 tggcaagcaa cgaagctttt ttgaaaagta atacgatcgt tgcggctaca gttatcattt
    15061 tccgattcgg ttctgtttta ctagggatca tcacattcgt ttatatttta tatgcaaatt
    15121 cctttttgat gacgatgcgg caaaaagact atgcaatgtt tatgatgctg ggagcaaaag
    15181 gcagaaaaat cgcacagatg attttttctg aaacattctt agtagggatc gcagctactt
    15241 tagtgggttc agctgtcggt gtaggattga caagtatcgt ccaccgatta ttagtggatc
    15301 agttagatct caatatttcg cattttacac cttttagtat tcacgggttg ttgatcactg
    15361 ttttgttttt tgctgttttg tttttattag ctgctgttgt caatgctttt tcgattgtca
    15421 aaaaaccgat tttagcattg attcgtgcgg atcagacacc aacaagaatc aagcagcata
    15481 aattcttgtt tttccttgaa gtagtactgg gaattgcttt tctaggctgc ggttactata
    15541 tgatgaaaca cgtggggacc tatcaagtct ttggtatagg ggtagcctta gttacgatcg
    15601 tattaggaac ttatttcatt ttccattctg tgatcatttt ctttttatca ttactaaaga
    15661 aatcagaaca gatttcattg aaaaaattga acaatttcac attgtcacag ttaaactttc
    15721 gtattcgtga atatacacaa atgctctcaa tggtcgctat gctgtttgcc ttggcactgg
    15781 gcgctttgac ggtaggatta ggttttaaaa atgaaattgc agacttgaca gaaaacaatt
    15841 ctggatatga tctagtgatg aataatcctc gggcagaaga tcagcaaaaa atcaaagaac
    15901 tttcaccaac actttctgct tcttatactc aaaaagaaga tgcgggaacg atttactata
    15961 atgcaagtga atttgcggct caaccattga tcatgataaa acatgaagat ggaacaccgc
    16021 cgaagatcac gaaagaaaaa gttcctgcta aaaaaatgaa tgaactgact gtacaagagg
    16081 aacttcgaag ctatgaattg ccggaacagc aagaaaaaga aatcaaggta gtcagtcaat
    16141 cagaatttga tcaactgaac ttgccacaat ccactttaca gctagttcag gtaaaagact
    16201 tccaagcaaa cctgaaacca atcgaaacac ttgttgctca aaataaaatg aacaatccat
    16261 ctttgcaaaa agtagagtac agcaaccaga aatatgaaat gtatgaagtg tataatggtc
    16321 tattctctgg ttttgaattt atgggattct tcctaggttt agctttcttg accatgcttg
    16381 ctagctgttt gatgttcaag atcttgtcag gaagcaagag tgacattgct cgttatgaaa
    16441 tgcttgaaaa gataggaaca cgacgcgggt tgcttaaaca atcgatccgt agagaagtag
    16501 gcgtgttatt cttagcacca ggaatcttag gtgtagtcca tgtcttattc ggattacaaa
    16561 tgtttggtct attcatgcaa aatccataca aagatatttg ggttccgttt acgatattct
    16621 tcgtattgta tttcatctac tatgtactga cgacatggtt atatactgga atcgtattga
    16681 aaaagagatt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa gcaaaaatag
    16741 ctcctcatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt
    16801 ttgttcggaa aaagaggttg tgacaatatt tttgtcacaa cctttttttc acggtctttt
    16861 attagaatat agtaaatttt ttctcgttac tcacggaata agctgttaag aaaacggttt
    16921 ccatgtatgc tggaatcagt gcaaatgaaa gaaaagaggg tgcaaggaac atggaaatca
    16981 atgaacaaaa ttttggcgaa aactatcact tgattacgat cacgaatcaa aatgggacat
    17041 ctttgtctgt cagtgatctt ggggcacggg ttgttcattt tcaaacaata atcgataatg
    17101 aaaaacgaga gttgatctta ggttttgatg aagcaaaaga atatctagaa aaagaccctt
    17161 atatcggtgc ttcaatcgga cgtatggctg gacggattac gaatggcaca ttcaaattag
    17221 atgatgaaac gttcgaagta aaaacagacc cggacactgg tcattgttta catggtggtg
    17281 cacctagctt tgaagccaag cagtggcatt atacagtcat caatggtgaa aacgaagcat
    17341 cggtcatttt ctatcagact agcccagata tggaaaacgg atttcctgga actttagatg
    17401 tagaagtacg gtatacgctg acgaacgatg atacatggcg agtgacggtc caagggatca
    17461 gtgaccgcaa aacagtattc aatcctacaa atcatgtcta tttcaattta accggtgatc
    17521 cagcacagtc aatcgacgaa catatacttt ggttgaatag ccgattattt gctacgctca
    17581 ataaagatac aacgcctaca ggagaagtag tttcagtaag tggcacagca tttgacttcc
    17641 aacgtcctaa aaaattaggt gaggtctttg ccagtgattt tcgccaatca atgatagtgg
    17701 gcggcatcga tcatccattt ttgttgaaaa aacaatctgg tttactaaat gctgcggaat
    17761 tgacaagccc agatgaaaaa gtatcgatcc aagtaaaaac agatgcttca ggaatcgtga
    17821 tttttacagc aaattttgga gaagatggac cggaaatgcg cgggaataaa ttagtaaatc
    17881 atggcggtat cacatttgag actcaagaac tgccaggagc ggagcgactt gaaagttttg
    17941 gagatgtcac tctggaacct aaccaagtac gcgagtttgt aacggaatac aaaataaata
    18001 taaagaaata gaataaatta aaaagggagt gtgacagtgt cacatcccct ttttaattta
    18061 ttctatttct ttaaaggcag atcaagccag aatgatttgt ctaaacttaa caaggttagt
    18121 acaggaacag ttgcagcttt aactgtacga gtagttgttt ctggtatctg tcttgccgta
    18181 aaattgttcc acaaatccca gattgaagcg acacggaaga tggaagaagc gttgttgacg
    18241 cgttttatcg ttgaaaattc taatcctgtg attggcacgc catctgttgt ccatttgatt
    18301 ggcacatcga atcgcttaga catattgagg atttcagcgt ttgcttcttc agttgttgct
    18361 gcttcttttt tcggttcatc atattttgtc aggtcgtacg cttcgatgat cgcgttcaat
    18421 ttttgtgaat attggcgatc tgtagcataa cgtccttcca aatatttggt tgcttctttg
    18481 tagtcttttg tttccgactt ccaagttggt ttgtagaaat caggattgcc agtcagtcca
    18541 tttttgatca agtcggcata gtcttccaaa ctttccttgt aagaaggata tttacggaat
    18601 tgtgcgcgga tttggtagct ttgtccggaa ctatcttgtt caagtgtatt gaaggtcacg
    18661 ctgcttcctt tatatgatcc tttgatacca aaaaggttat gatttggttc gcttgataat
    18721 aagctgtttc cagatccact ttcaaggata gcttgagcca tcatgactga tgcgtagatt
    18781 ccttcttttt gcccgatttc ctgtgcatca tctgcaatct ttttcaagaa ctgatcagtt
    18841 gtttggtttt gactgaaatg gaacgagcca tctaatccat ctaaaataga tgagccgcct
    18901 gtcagcgaac ctgaagcagc aggtaaacct gctaagttta ctcggacagc aaaatcaggc
    18961 gtgaaatctg aaatagaagt tactcgaact ttatctcctg gttgaggcgc atggataaat
    19021 tgtccgttcc caatatagat acctacatgg tgagtaacac cggaagaagg tccccagaag
    19081 acgaggtcgc caggttgggc ctgacttact ggaatctgcg tacctgcata ttgctgttcg
    19141 cctgtccagc caccgatata atgaccggtt gctttcatat atacgtaata agtcaaacca
    19201 gaacagtcaa aagtatttgg accttttgct ccccatacat atggttttcc aagatgcttg
    19261 aatgcttctc gaacgattgc ttgttggaca ttcgttgtat ttgtaggcaa tacagcatca
    19321 attggtgatt ttacaacaaa atcagaagaa gcagaagatg gattctctat accgctttga
    19381 tttgctgtat ttggacgaga tgaagcattg ttcgttccgc cattcgatga accattgttt
    19441 ggatggtttg gttctctctg agtatttcca ttgttattcg atccagatgg gtttgtttga
    19501 ttcgaagaat tcccgctgtt cgaattattg ttattattgt ttgaattatt tgaaccatta
    19561 ttattgttgt tattacccac atctggtttg tttggcgttt ccggatctgg tgtactaggg
    19621 acttcttcac taggatcagt tggtttctct gttgaagtat ccggtccagc tttaaattct
    19681 gcagtaatag ataaattgtt cgtacctact gtaaaggtct ttgcatcata atttacttct
    19741 ttggcaccat taacagcgac tgaagcaatt tgttcacctt cagctggcgt aatagtgtaa
    19801 gttaccttcg tttccgctaa taaaccttct accgttccac tttccgtaat atccaaaggt
    19861 tgctgttcag gggaatccgc tgtcgaagca gtcagttgga tcttaccaat caaagaagga
    19921 gcaattgtaa gggaatatgt ctcggctggc ttttcatttt ctgatggatc agccggatca
    19981 atttcagttg gctcggtcga tcctgttgtt gagttagttg ttccagttgg gtcttctgta
    20041 aaagaatccg ttgtttcact agtagctgag ctggatgtag tcgtatctgt tgtgactgtt
    20101 tgatcagcta tttgattatc tacggcaaat acggtattgg tcgacaaaac agacggagca
    20161 atcagccaag tagcagctag caaacgtatc gtttttttat ttttcataat aaactagtcc
    20221 ttttcctttc attgattttc tgtcttattc agcattcatt agacattttt tggaacagat
    20281 aatcgtgtcg aaaagctttt tcttttcata aatctgtctg tgtattctaa ataaaacaat
    20341 ttgtaaataa gcaacgagca ttcattcgtt tttctttgac gttcatttta ttgcatagac
    20401 cacctttgtt tggggataaa caagtgggga taaaaatggt tatgcatatg taaattatac
    20461 caaagtttgg aaagtatcac aaaaatttat aaaaataatg atcctaaaaa gaaaaagact
    20521 gaaatatgtg ataaacatct catacttcag tctttttcat taactattca taagacatta
    20581 ggtcttcatc aaacccgcta acgagagtag tgatcattgc tacgactaga ctaacagcca
    20641 gtcctgctaa gtaccagaaa aaagtaccgg aaatgaatgc aggcaatgtg gtcagactac
    20701 caaatacaaa agcgatcgct ttcacttggg caaatcccat tacagctcca ccagcagctg
    20761 caccaatgca agcagcaaca aatggttttt tcaatgggat cgcaattccg taaacagttg
    20821 gttcggtcac tcccgcaagt aaaatcgaag caaaagcaga accggagatc gaacgggttt
    20881 ttgaacgttt acttcgcaga aatacaccta aagctgcacc agccattcca aaattggctg
    20941 ctcctgtcaa cggaacgatt cggtcgaacc cataagcaga gatattactg atcatgacag
    21001 ggtttacagc ccattggata ccaaatatta ccaaaatatt ccaaccacca gcgatgattg
    21061 cgccactgat cggtccgtta atatccatca tccaagtaat tgcggcagct aaaccttcgc
    21121 caaggtaaac acccgcaggc ccgaatacca ttaacgtcaa aggaaccgtg ataactaatg
    21181 aaagtaaagg tacaaatact aattgcatat tttcgcgaat atattttttg aggaattttt
    21241 caacaaaaga ataaaagaaa atacctaaaa tcgccggcat gacagtagac gtatactgca
    21301 tcagtactac aggaatcccc agaaaatcag tagctgcttt gccactgtct gaaagtaaag
    21361 aggtcagatt cggttcaatc agtgctgcag caatgacagc cgcaatatat ccattcactt
    21421 taaacgtttt ggcagcagaa aaagcaagaa agattggcag aaaataaaag acggcattcg
    21481 acgcagcaga caaaatatga taagttccgc ttgtttcact aagccagcca atcgtagtcg
    21541 ctaaaacaac cagacctttt aatataccag aaccggcaaa cagcggaatg atcggcgtaa
    21601 agatttccga tatcaaacca aatagttttt cgatcggatt tagcttttct ttcggagctg
    21661 aatgatcgat ttgacgcgtc aattccttgt aagcaggagc caatccctga tccatgatta
    21721 tttctgcata tctatcgagt aaaatgaaat acttaatgga agggatttgc tgttttaatt
    21781 tttctgcatt ggctactggc tgttttttca atttgatacg aagccgagtc gcacatggaa
    21841 ggacagaatc aatattgtct tttcctccca actgttcaat cagcatatga atctgctcgg
    21901 acagtaccat ctgttcagga ttcattgtcg tttccattag aagaccactc cactcactaa
    21961 tataatattg gcgtaaggtg tcatttcgcc tgtacgaata aatgcatgac agttattcaa
    22021 ctcttttttc atttcttcat gtgggataaa gctaatcggt gtatctggta acaataattt
    22081 gattttttcc aatatttccg ggttcattgt ctttatttct tccgccaatt caatcgattg
    22141 tacctcaagt tcttctaaaa cgttttctaa aacagataaa aaacttggaa gaccgtttga
    22201 gacagccaaa tctatttttt cagtaccaaa ggggacaggc atgcctgcat ccccgatact
    22261 taatttatca aagtgcccca tttgtgcgat tactcgtgaa atatctgaat tgattacttt
    22321 tccttttttc atgtttgttt cttcctctca ttgttaattt tagactgctg attgttctaa
    22381 agcttcgcgg taagggatag aaggttgcgc accataagac tgcacagcaa cagaagaggc
    22441 tagatttcca taaaggatcg cttctttcaa gttactaagg tctggctgaa gtgtgctgct
    22501 taatgcgcca ataaatgtat cacctgcggc tgttgtgtca acggcatcca ctttaaaagc
    22561 agggacgata ccgtgttctt tttctgtatg atagaaagcg ccggcactgc ctagtgtaat
    22621 gattactgtt ccaataccta attcatggag tttttcggct gctgcgacca aactgttatg
    22681 atctgtcact ctgattcctg taatgatttc tgtttctgtt tcatttggta taatgatatc
    22741 tgtcttttca agtagttcag taggaatcgt ttcacgagct ggtgcaggat tcaggatcgt
    22801 tgtttttcct gcgtcttttg caatagaaaa agctaggatc gtcgcatcta agctactttc
    22861 aaactgagca ataataaagt cactgtttgt aatcagttgc ttgtttttta ggacttcttg
    22921 ttcatggaaa gcattatttg cccctgcatg gatcaagata ctattttctc ctgctgcgtc
    22981 taccataatc attgcttgtc cggttgtggc gccttggatt tcagctatcc cagatgtatc
    23041 gatgttttct tttgtcagta gatctaataa ctgttgtcct tcgctgtcag ccccaacgcc
    23101 tccaataaaa gatgtccgtg cgcctgaacg tttggctgcc actgcttggt tggcaccttt
    23161 acctccgcca gcgtgaaaaa tctcatgcgc atgcatcgtt tcgcctggct tgggcatgtt
    23221 ggttaaacga agggtagtgt ccatattaat acttccaatt actgtaaccg tgttcatttt
    23281 acaaacctcc aactatctca tttattttga tgggaaaatt attttttaaa acgttttagt
    23341 aaaacgtttt aatagttcga taaaaatata gcacaccttg aaagctattt caagggtgca
    23401 gttgaaaatc ttttttctaa tcgtacaggt aatctttttt cttcccattc tttttctggg
    23461 aattggatcc gatctaacaa taacttggca gatgtttgtc ccaattcgaa gattggttgt
    23521 gcgatcgttg tcagtttcgg cttgatatac tcgcacatat ctatattatc atagccaata
    23581 atgctgtagt cttcagggat gctttttcca gcttcctcta atccgcgata taatccaaaa
    23641 gctaattcat catttaaagc aaacacacca gttgcagcag aatcaagaag ttctgctgtg
    23701 atctggtagc caccttgttt tgagaactgt gtaggtaaga ggatcagttg gtcgtgaggg
    23761 atttggtaaa catcaagagc agatttaaac ccctcaatcc gagcgtggac attttccggt
    23821 ggattttcag gatagacaag ggcgatcgtt tgatgtccta gactaagcaa gtgcatgccc
    23881 gctaggtaac caccgcgaaa atcgtctgtt cgtacggcat cactaaatcc ttcagatttt
    23941 ttctgatcca aaacaatgaa gggccggcct tgttttttca aattttcgtt gattgcatct
    24001 gtagagacag cagaagtcgc gataatgaat ccatccacac ctcgacgtgt gagctcggct
    24061 agatattcga tttctttttg atgatcagaa tcagcattac ataatatcgt gacgaaattc
    24121 tgcttataca agatatcctc aattcctcgc atcagtgtac tgaagaatgg attcgtgata
    24181 tcaggaacga gtacaccaat tgttttcgtt tccttggtaa tcatttgtct agcaaaatag
    24241 tcaggctgat agcctaattc ttctttggca gctaaaactt tctgaacagt tttcggactg
    24301 aatttctccg tatttccatt taatatcaag gagacagttg tgattgaaac gccggaaagt
    24361 ttagcgactt ctttgattgt gatctttttt ttcaccatgt tcatactcct atctaaatcc
    24421 tgtggttatt ttcccatgaa atcaaaaaga agtaaatgaa aatcacgtgt gccagtactt
    24481 atttgctttg ttggatagct tcgattattt gtttcgttga gcgtactcgt gcagttttcg
    24541 gaaatatctt ttttatgaac aattgatggg attctttgtc acgatcactg caagcatctt
    24601 cagcaagcac gatatggtac ccgtgttgaa aggcatctaa tgcagtagca tatacaccgt
    24661 ttgttgtcgc tacaccgctt aaaatgatag tttcgattcc acgccggcga agttgaagat
    24721 caagagaagt accaaaaaaa gcacttggat tgtattttgt gatagtcaac atattatctg
    24781 tatctttcaa agaatccttc aaaagtaaat cagtgaattc tggaggtaca gaagcagtca
    24841 ttccacccat atcagtttgt tgactcaaat aagggaaagt ggagatgtct acgttcacta
    24901 aaactttcaa ggcagcggta cgtttcaatg ttcttactaa caaatcattg tttgtcagaa
    24961 tagatgctgc agtgtgtgga gagagtgtac cgttatttac gatctctttt tgcatgtcga
    25021 tcgcgacaaa agcagttttt gataaatcaa aaatcatatt ttcctttaaa tcattcatga
    25081 tgttccttct ttcaaataac aatgtttttt atgtaagtaa atcataaatc gtttatttgt
    25141 caactaaatt aaaggattcc tttctttagt ctagagaaat tcagtggtaa aataaataag
    25201 tgtgagaaaa cgcattcgat gcatagatat agcgagaaat atcgtgaaaa tggaggaatc
    25261 agagtgaagt atgtcgaagt aaaaaatgaa tacaaacgat acaaaatggg agaaacgacc
    25321 attacagcaa atgacgatat ttctttttca attgaaaaag gcgaattagt gattatactt
    25381 ggtccaagtg gagcaggaaa gtcaacgatt cttaatattt taggtgggat ggatacacct
    25441 gatgaaggtc agatcattat tgatgacaca gatattgcgc aattttcaga taaacagctt
    25501 actgcttacc gacgaacaga tgtagggttc gttttccaat tctacaatct cgttcctaat
    25561 ctaacagcaa aagaaaatgt ggaattggca acggaagttt ctcctgatgc gcttgatcct
    25621 gtagaggtat tgaggcaagt gggcctagct catcgattga ataactttcc gtcccaatta
    25681 tcaggaggcg aacagcagag ggtttcaatt gctcgtgcac tagctaaaaa tcccaaactt
    25741 cttttatgtg atgaaccgac aggcgcgctg gattttgaaa cgggcaagca agtattgaaa
    25801 ttattgcaaa acgctagcag acaacacggc aataccgttt tgatcattac acataattct
    25861 gctttagcgc ccatcgctga tagagtcatt cacattaatg atgctaaagt aaggtctgtt
    25921 gaattaaatg atcatccttc atccattgat gagattgtat ggtaggggga ttttatgaaa
    25981 acaagaacat atcttaaagc aggttttcgc gaaattcggc aatctaaagg acgattcatt
    26041 gcaatcatcc ttattgtcat gctaggaaca cttttatttg taggtgtcaa aactgctgga
    26101 cctgtcatgc aaaaaacgat ggatcactat gttggtacag caggactttc tgatttgcaa
    26161 atcgtttcta ctggtggctt gacacaaaaa gatattgctc aagcagaaaa gatcccagat
    26221 gcaaaagtag aaacaggaaa acagatctat tattccaata ctggcaaaaa cgaagtgatt
    26281 caaatatttt cttataacaa aaataacaag cagaacaagc tacaattaac tgatggaaaa
    26341 ctcccggaaa aaccaaacca gcttgtattg gatgaaaaag cggaagatga agggtataaa
    26401 atcggtgata tttatcagat tgattcagat gaattgaaag aaaaagagta taccatcacg
    26461 ggctttgtcc gttctccatt gttcatcaac aatttggaga gaggatacgc gaacgtcgga
    26521 aatggtagcg tcgattattt tgtctattta cctgaatccg tttttaaaac agatatttat
    26581 tctgtcttat atcttgattt tacaaacgta aagaatttga atacgtacag caaagcttac
    26641 aaagataaaa tggagcaaaa tcaagaaaag gcagaaaagt atttacaaga tcgacccgaa
    26701 gaacgcttag aagagctgaa aaaatcggcc aacgaagaat tagaaccggc acagcaaaaa
    26761 atagcggatg gcaaagcaca aacaacgcaa gcaagaacac ggttagaaga tgctaaaaaa
    26821 cagttagcgc aacagtcagc aactatccag cagcttcctg aagcgcaacg aacaatcgct
    26881 gttcaaacat tatctcaaca agaagctcaa cttgctgaac aagaaaggca attagttgag
    26941 aaagaacgtg aactggcctc tgcagaggaa gaattgaatc gaaatgcaga aaaaattgaa
    27001 aatttaacta aaccatcata cctatacaat gaacgttcag aaaatgtcgg ttttcaagaa
    27061 tttggtgatc tgtctgatcg tatcgctgcg attgccaatg tttttcctgt tttctttttc
    27121 tttattgccg cattgatcac ctttacgaca atgacacgta tggtagaaga aaaccgcagg
    27181 gaaatcggga cattaaaggc gttaggttat acgaaagttg aaatcgcaaa aaaatatgca
    27241 atctatgcaa gtctagcctc agggataggt attgttttag gaacgatatt aggaacgaat
    27301 cttttgccaa ggatcatttt tgagctgtct aacgagcggt atgatattgg gagtgcgctt
    27361 attttttatg actggccgcc gattttacaa gcagctgccg cattcttcat tgccgcattt
    27421 ggcgctgcaa tgatcgtttt attcaaagat ttaagagaac ggcctgctgc attgcttcaa
    27481 ccgaaagcac cgaagccagg gaaacgcatt tttcttgaat acatcactcc gctgtggtca
    27541 cgccttagct ttaatcaaaa aatcagttac cgaaatctct tccgatataa gtcaagaatg
    27601 cttatggcga ttatcggaat tgctggatgt gccgggctga tggttgcagg cgtgggattg
    27661 aaagattctc taagttctgt ttcagccaaa caatttggaa cgatcattga ctatcaagca
    27721 atcgttacat tggattcatc cacggaagat agtcgtcaaa aagcagcgga tatgctgcag
    27781 aagcaagaaa aagtaaatga gatcctagct attcatactc aaaccgtaga attgagaaaa
    27841 aaaggacatg cttcgcaaag tctgacagtg atcgtaccaa gtaaaacagc tgatttggat
    27901 cgttttatcc atttaactga tcttgaagag aacccacgct ccttgcctaa aacaggaatc
    27961 gctattacgc aaaaagtagc agaactattt gacttatcta caggagatca tatttcgctt
    28021 tatgatgaag atcaaaaaga atggaaagtc gaagtaaaag aaatcgtgaa aaactatcta
    28081 ggtagcttta tttatatgtc ccctgaatat tatgcttcag ttactgatca atcgatgatg
    28141 gataatgcat ttttgctgcg tacagataag atgacaacaa aagaagaaga aatgctttcc
    28201 gagaaactgc ttgccacaga cgctgtgaca aatacgtctt tcatgtccaa acaaatcgaa
    28261 acgcaagaag aatcaatggc gaacttagac tcggttgtct taatctttgt cgtattatca
    28321 ggactgctgg cttttatcgt cttgtataat ctaactaata tcaatatttc cgagcgtgta
    28381 cgcgaattat ctacaataaa agtccttgga ttttttgata aagaagtcac gatgtacatt
    28441 gttcgagaaa atatcatctt tactctttta ggaatcatcg gaggatttgg tgtaggatat
    28501 atattgactg acttcatctt gcaacaagcg tctatggaga atgtcatctt tccattagtg
    28561 atcacatggt gggcttatgt cttatcagca ggattaacta tcgtatttac ggttattgtg
    28621 atgattgtta cccatttcaa attaaagcat atcgatatga ttgatgcgtt gaaatcgaat
    28681 gaataaaaac agaggttgtg aaatcagcgg tttgacctga gtattagaga aacaaacggc
    28741 aaaatagttt ttcatatttt gccgtttttt gagctaatac cgaaggacag ctgattgaac
    28801 accatgaatc agaggttgta aaaaagccgt cctgcatcga gcaaaaagaa tactcaaata
    28861 aaattagctc ctcatgtttt acatttgaga agactgattg ccgtagataa aagcttttga
    28921 acaccattta tagaagaaac aagaatattt tgctatttta aacaagagga tagacaaata
    28981 catgtctgat ctcttgtttt ttattgggca acagacctct tagaatgtat aaagataaat
    29041 tttacaaacg ctttcggttc agttataata ataaatgata acttgtatat ataagttgtg
    29101 gtaggtaata aatcagttga atggaggtaa atatccatga catttaaaga caaagtcatt
    29161 taccaaatct atcccaaatc ttacaaagac agtaatggtg atggaattgg agatttaaaa
    29221 ggaatcaaag aaaaactccc gtatctgaat gatctaggca tcgacatgat ttggctaaac
    29281 cctatttatc caagccctca aaaagacaac ggttatgata tctctgatta cacagccatc
    29341 gatcctatct ttggtacgat ggaggaattc gaacagctaa tagccgaagc aaagaaatac
    29401 cggatagaaa tcatgctcga tatggtgctg aatcacgttt cgacagaaca tgaatggttc
    29461 aaaaaagcac tagcagggga ccagcattat caggacttct tcattttaag agaagagcca
    29521 acggattggg tatcaaaatt tggtggaagt gcttggtcgc catttggaga tacggggaaa
    29581 tattatttgc acttatatga tcggacacaa gctgacttga actggcggaa ccaagcagta
    29641 agagaggaac tattcaaagt tgttcgtttt tggatggaaa aaggggtaaa aggattccgt
    29701 ttcgatgtta tcaatgttat cggtaaagac gaacaattga aaaataataa agaaaatgat
    29761 ggcaaacctg aatatacgga caaaccaatc acccatacgt atctaaaaga attgaaccaa
    29821 gcaacgtttg ggacggattc cactatcatc acagtcggtg aaatgagctc tacgacgatc
    29881 gaaaattgta tcttgtatac agaacctagt agagaagaat tatcaatggt ctttaatttc
    29941 catcatttga aagtcgatta tgaaaatggg aataaatggt ctactcctcc atttgatttt
    30001 gcagaattaa agcgactatt tcatacatgg ggagaaaaga tgagtgaggg taacggctgg
    30061 aatgctctat tttttaataa tcatgatcag ccacgtgcgc tcaatcgatt tgtagctatc
    30121 gatcagtatc gaaaacaagg agcagagatg ctagcaacca tgatccattt gaaccgtggg
    30181 acgccctata tttatatggg agaagaaatc ggcatgatcg acccagacta ttcatcgatt
    30241 tccgactata ttgacgtaga aagtttgaat gcttataagt tactccttga acaaggattc
    30301 acagaaaaag aagcgtttcg tcggatcaaa gcaaaatctc gcgataactc tcgaacaccc
    30361 atgcaatggt cagacacaga acaagcagga tttactacag ggaaaccttg gttaaaagtt
    30421 ggaggcaagc tagaagagat taatgtagaa aaagaactat cttctgaaga ttctattttg
    30481 tcctattaca agaaattgat tcggctgaga aaaacatatc caatcgttgc acaaggagat
    30541 tatcatgctt atgaagcaaa tcatccggaa gtttatggct ttcttcgcca atttgaagga
    30601 cagcagctgc ttgtattaac aaatttctat gataaagata caaggatcgc catcccagaa
    30661 ggattcacag aagccaatat tcttatcgat aattattccg atactgttct tcatcaaagt
    30721 ctggagctaa aaccatacca ggcaattgct ttgctgaaaa attaaaacaa aaacacaaaa
    30781 cgtcgttcct acgagctatt ctcgtaagat cgacgttttg tgttttattt aaaataatct
    30841 tcttcagaaa atgaagagtt ttcatactct cctttatcgc cataaaattt attgtagcgt
    30901 tgtttgaatt tacggaaaat aaaagtaacg agtaatttga ctaacgtata gataggaata
    30961 ccaaaaataa cgcccacaat tcccattaga tcacccatga caagtaaaac gattaagatc
    31021 gtaatcggat ggatctgtaa acgatcaccc attactcgag gaatcaccaa gtcaccgtgg
    31081 agaagttgta cggcaaacca gacaatgaca aatttgacag ccataaaagt agagtcttgg
    31141 aatgcaatga tcaaacctgg aaagaaggcg ataaacggcc caatatatgg aatgatacat
    31201 aacaacccag cagaaatagc taaaacacta gcaaattcta atccgatcag taagaaacaa
    31261 acccagtaga ctgctccaag gataaatgaa gcaatgattt gcccctttag aaatgaaccc
    31321 aattgttgat tagcaatctt tgtcaaattt ttaaaatctg tacgaaatgc tggtgggaca
    31381 atcgctaaaa ctgactgata aaatttttga ggatctctca aaaggaaaaa agcgacaatt
    31441 ggaccagtaa ataaagtaat aaaaatagct gtaacagttg aaaaaatgtt gctgatccgt
    31501 tgtgcgccac tttcccaata atttccaata aatccagcta tatcagacgt cacgtcgtca
    31561 atagaagcga aaaattgatt aaatgaatcg gcaaaaggtg ttttctccaa aaattgtcgg
    31621 agactctctt gaaaatcttg aaacaaatct ggcaaactac tgatcaatgt ctttgcctgt
    31681 tcttcaagaa aaggaataag ccatatgctt ccaagcccca ataaaaataa aataatcaca
    31741 taaacgataa tgactgacaa gttcctcgaa aggtgcttgc tcaaacgttt gatgactggt
    31801 tccaaaagat aatacaagat cagtgcaaac aataatgggg gcaagatagt agcgataatg
    31861 attccgacag gcttgaatat aaacgagatc tgatggaaaa aataaatgat cagcgcaagt
    31921 aagataacta ttcctaaaac atagtaagag gtttttcctc ctaaaaagcg gatcaaacga
    31981 ttcgttgtat ctgtttcttt tttcactctt tttcctcctt tatctataac ttcattatag
    32041 acaaaagcgg gtataaaagg aaaatgatag aggttgattg caaaaatatc gtcaatcatt
    32101 catataaact ttctcatcaa ttaaaataag aaaacgcttg acagttcttt taaccatatg
    32161 ataaattaaa tcctgttgct aaaacgtaac tattacggtt tgcgaaaagc gaatcggaac
    32221 attcaaatga aagaagatga gaagaggagt gtcataaatg aaacgattga taggtatatt
    32281 ggccatgctg gttttagcag gtatgttaac tgcttgcggg gcaagtggga aagccgagga
    32341 cagtaaagaa aaattgagcg tgatgacgac cttttatccc atgtatgatt ttacaaaagc
    32401 aatcgtcggg gatgaaggag aagtagagtt attgattcca gcagggactg attcccacga
    32461 ttatgaacct tctgctaaag acatggcaaa gatccaagat acagatatct ttgtttataa
    32521 tgatgaaaac atggaaacat gggtccccgc aatccaaaaa acattacaag aaggcaatgt
    32581 ccatacgata aaagcgacag aaggtatgct tttacttccg ggaagtgaag aaggacatga
    32641 tcatgaccat gaacacgggg aagaaggcca tacacatgag ctagacccac atgtatggct
    32701 agctccaagt ttagcaatca agcaggtagc aaacatacgt gatcagctga ttgaagctta
    32761 cccagaaaaa caggaagtat ggacaaaaaa tgcagcagcc tataccgaga aacttcaagc
    32821 actccatcag ctttatcaag aaacctttaa gcaagcaaaa caaagatctt ttgtcacgca
    32881 acatgctgca ttcaactatc tagcgttaga atatggattg aatcaagtat cgattgctgg
    32941 tctttcttct agtgaagaac cgtctgcggc gagaattgct gaactgaaac actttgttaa
    33001 agaacatgga atcaactata tttattttga agaaaacgcc aaagatagta ttgccagaac
    33061 gttagcaaac gaagcaggtg tatctttaga agtattgaat cctttggaag gattgacgaa
    33121 tgaacaaata gaaaatggag aaaactatct ttctatcatg gaagcaaacc tcgaagcgtt
    33181 gaaaaaaacg acagagacag aaaacccgct agaagatact ttgaccccca aaaaagaaaa
    33241 gagcgtctac aacggttatt ttgaagacga ggatgtacaa gatcgctctc tttcagattg
    33301 ggcaggaact tggcaaacag tagatacgta tgtagaagat gggacttttg atcctgtttt
    33361 tgaatataaa gaaaaattga atcaggataa gacagcacaa gaatataaag aatattatac
    33421 gaagggctat caaacagata ttgcttcaat caagatcagt gagaaagaga tggcatttac
    33481 gtttaagaat ggaacaacga aacgttcaaa ttatcgttat gtagggaaag aaatcttgac
    33541 ctacgaggca ggaaaccgtg gcgtaaggta tctattcgaa gcagaagata aggaaagtgg
    33601 cgcttttaga tatattcaat tcagtgatca cacgattgca ccggctgact ccgaacattt
    33661 tcatttatat gcaggaaatg aaagtcaaga agtattgctg aaagaaatgg agaattggcc
    33721 aacattttat ccagatacaa tggatggacg tgaaattgca caggaaatgc ttttgcactg
    33781 ataggcaaaa aagaaccgaa gggtttggat cggctggtca tttagtcggt ccaaactatt
    33841 cggttctttt tatgaaatca atttctttaa tccacggata gaggctggga tggtctcgcc
    33901 gtttgccaac gtgacttctc tggttttttt attaatcgac cgcacatttt gtgtattgat
    33961 aacataggat ttatgacaac ggataaaatt ccgatgcatt ttctcgattt ctttgatctt
    34021 ctcatagaat tgtaattggg catgagtcaa atggacttcc agtttatgtg gcgctcctag
    34081 cgaagtagaa aaatattgga tgtctttgat cggtaaaaat ttgatctcat cattaaactc
    34141 tattttgaag atatcttttt ggatttggga catttgaaaa tcttcgaaaa ttttgctcag
    34201 gatatgctcg acattttctt ttaaatcata aagatcttct ttgacgatat aatcagtcgg
    34261 ttcgatgttg ctttttaaga ttttcatcga catttccgta tgggaagtca catagattat
    34321 ttttcctaaa ggatctaatt cacggatcaa tttaccgatc gctacaccat ccatttcact
    34381 gtcttctagt tcgatatcta aaaagtaaat accaaaagaa gaagttctga tcttggctgc
    34441 attgagaagt tcttccggat cagaggtaga aatatggaca taactgtcta agttttcaat
    34501 catgattcta tttttgatca ccgttgataa aacttctaat tgttttggat cgtcttcaca
    34561 aatataaatg ggaatcatat cattactcct ttattttatt tgtatataaa tcgtttgaga
    34621 aaaacgctgg ttttcaattg atgtttcaag gaaaagataa ggattggtct ttgtcaattc
    34681 atccaagata aacaagccaa ggccttcgtt ttttggattt gtttttgttg agaacccttt
    34741 ttgtttcaac tggtttaacg gtaatgtatt tgttgttgta ttgatcacac gaatcatcac
    34801 ggaatgattc ttcttgagta tggtcaattc gatttttttc ttctttgcag cactagctcc
    34861 ttcaatcgca ttgtccaaga taataccaag catacgtaca aggtttaccg tatgtttcgt
    34921 atccagttcg attggctcag gaaaatgaag ctggacgatc aacccttttt cctgtgccat
    34981 catgagtttt aatgacagta aactacggat ctcaggaact ttcatattat ccaacatact
    35041 tagattggcc ggaaaaaggt tcatcatctg gcgtgtaggt aatatcgttt gatcataata
    35101 agaccgtaat ccttctaagt cgccttctga aatatagctg tgaagagaaa aaagcagatt
    35161 ttggtaatca tgtttgaatt ctctcaagtc ttgatagttt ttttctagat ctttgatata
    35221 atcctgttgc atcctgactt gttgctctaa taactgatca gctaatttct tattagagat
    35281 tttccaataa taaaccaaga tgatcaggcc aacacacaga tatagaatga aaaaactcgt
    35341 attcaaagct aagacatcag gtgtttcacc agaaaaacgg gtataaaaaa taatgatata
    35401 gtatgtaaat aatatcaatg tcccgatcgt accgatcata cggcggtcca cagtgtgaaa
    35461 ccaagtctct aacgattttt ttaaacaaaa agctaataaa gcagataaaa aagcggataa
    35521 gacaatgtga aaatactgca atgaatctcc tggttcaata accgaagatt tcaaaacaaa
    35581 aaaatcgccg atgcttgtta agtgatctcc taaaagcgac gtcaataacc caaaaggaag
    35641 cgcgtaaacc aattgttgac gcgaagtcga aaagaagaaa aaagtaagca tcagcattcc
    35701 tatagcaatt agagcagtaa aaatccctaa aatcgaatag acccatccaa tcaaaataca
    35761 agaaatcaga atgactcccg caaacagata tttgtatcgg atgtgatggt caatcaataa
    35821 gatacaaatt gtgtaaatca aatattgcaa cgctatggac cataaaaaca taaagtacag
    35881 ctcccattga tttttaccaa attatagcac aattggcgta ttattttttt aatttttcag
    35941 ggattttgaa ttcagaactc ataccaaagc agcagccaga tacaaaaaag tcagataagt
    36001 tagttaattg tttaatgatt gtttttttca tgaaagattc ctccaaaatt catcaagtag
    36061 tttgtaatag gaagcaacgt agctatttct aaaacaatcc caagtagcaa ataggtagaa
    36121 aagtaagaag ctgagaaaaa taacgtaatg agagaaaaaa ttagaaacat gctgatcgcc
    36181 ttctttaata atgggggacg tttctcgggt tcaatgggat tgattgctgt acctcttgat
    36241 ccatagcgaa gcagtaacaa aaagcagctg attaacaaaa agaccatcat tgggaaggag
    36301 atagtcaatt gcagatgttt catcaccaag ggaacgcccc ataaataaag tagtgtccac
    36361 agcagacaaa cgaattcaga gtcggaatgc aatccataag catatctgcg gatgcagata
    36421 taagaaagaa aggtgattcc tgtttccgcc catgagcctg tcaccagaga aaagactaga
    36481 acgaccgcta gttttccaag attattcaat aaaacttcta agacaaattt tacttggaca
    36541 tacaccatat cttcttccga tttgtctccg ctgaataagg cttctaataa tttgttcaca
    36601 actttatctt tcatctcata cgtacctcca ccacaaattt tatgctaaaa aaaataaaaa
    36661 acgtcttttg tttcataaaa agtggttttg acatcaaaac cgtcatgatc tcctaaaaaa
    36721 atcttcgttt tccaagaacc ttaccaaaaa aagtgacagt tttgatacga aaagtacttt
    36781 ttatgacaag tttgtgcttt ttcgagtgat ttatgttaaa aaattactga ccttataaaa
    36841 ggtgatggag ggattcttat ggaaaatgaa caattgtttg aagtcggcga aacatatgca
    36901 tttaaatctg atttatttga atcaccaata aaaggaaaaa tagaaaaaat ctatgaaaat
    36961 agtgtgatga tacgtgtcat gaaatgcgca gtagaagaca atgataccgc tcataatctg
    37021 cactggcagt tagttgtacg caaatcaagt acaatagaag aataaaaaca gataaaatgt
    37081 tgagagcata aagaggttgt gagtctcccg tttagctctg agttacaagg aataatgtta
    37141 aaaaacagct tttcatgttt tatgaatatt gccttgtgac cgaggtgttg gcaggagaat
    37201 actgtttatt tgaaaaaagg gctgcgacaa gacttttgtc acagccttta ttttcatgaa
    37261 taggagttac ttttggctac ttttagagaa gtagctttta aggagcagat aaagtcaagg
    37321 cttttatttc tataaatgaa gtagtaaaat gaagaacaga ttttattaca ggaaggatgc
    37381 cgataattgt gatcattgtt gcaggaacga tcggtgcagg gaaaagcaca ctaactgaaa
    37441 tgcttgccca agatttagaa acaaaacctt tttatgagaa cgtggaagat aatgaagtat
    37501 tgccgctatt ttattctaat ccagaaaagt atactttttt attacagatt ttctttttga
    37561 acaaacgctt tttggcaatc aaagatgctt tcagccatga tgacaacgta ctagaccgct
    37621 ccatctacga agatagtatg ctgtttcatt tgaatgcaga tttagggcgt gtttctgaag
    37681 tagaagtaaa gcagtatgaa ggtcttttag aaacgatgct gaaggagtta gaagaaattt
    37741 cgccacaaaa gaaaccagat ctactggttt atattcgtgt atcctttgaa actatgttag
    37801 cgagaatcaa aaaaagaggc cgggaatatg aacagctaga acaagatcct gaactctatt
    37861 cctactataa agaactcaat cgacgatacg aagagtggta tgaacagttt gatatatgtc
    37921 ccaaaatagt gatcgatggg gacaaatatg atttcgtagc cgatccggca tgtggagaac
    37981 aaatcgtaca agaaatcaag atgcgggcaa agaaaatgac agaagaggca gatgcccagt
    38041 cgatccgcta cactacaaat aacccgaaag caaagggaat ctttacaact aaataatata
    38101 aaaactaagc aaattgctca ctcgcagata tttctctgtg agcagcatct tgcttagttt
    38161 ttttgattca ttgagatcaa atagtgaacc gattcgtatg ataaaattgc cataaatgaa
    38221 atgtctgagt gagggccatg atcaaaaata aaatggaaac gatcaaaatc gaatgggcgc
    38281 caaacagatg atgacagaaa acaaggacaa tagctcctgc gataaaggca agaacgacac
    38341 ttagatagtg gaaaaatcga tcaaaatctg ctttttcttt agaaatacaa taatcatata
    38401 agttcgttgc tacccctttt aaatttccag ttgtaaataa attagtgtag gcacgcccgt
    38461 tgattttatc aaaagctacc cactggatcg atgcagtaaa agcaatcaaa atcgttacta
    38521 atgcgggatg ctcatggacg ggtgtcaaac taacaaagaa aaaaatcact gcttcataat
    38581 atagaacaaa caagcgccag aaatgttttt ctttttttct aaaataatca attagatact
    38641 ttgttagaag aatccctaag aaaaagaaaa gggtagacaa tactttttta ccaacactta
    38701 gccattctcc gtcaaatgct tggatgatcg atagaatgat attgccagtt tgagcagagg
    38761 caaaagcacc atattggata taagtataac tgtccatggc tcctccgata aatgtcagca
    38821 aaagtcctat tgtacgcccc tcgtgaaagg aagtctgcat ttttttcatc accttttatg
    38881 aatatttttg tcttccttat cttagcataa acgattgaaa aaaaggaaaa attttcagaa
    38941 aactaaaatc atatcgcttc ccattttcat ttttagaaag gtctgttagt ataaagaaaa
    39001 aatagacaac gaaactttaa ataaccaact tgaaataaac aaattcaaag aagaaagatg
    39061 ggaaggaaat caatcagttg aatgaaaaag aaattctccg attacaaaaa gaattgaaac
    39121 gctgggagaa caagtataaa aagcttcaac aagtctttcg gctacaagaa gaaatcattg
    39181 ctacctatga agcggcttat ggcgaagcac ccggacttat tgaggaagaa gtacaagtaa
    39241 aagaaagtga aggaaacagc tctttcttta aaatgatgga gaaacgttcc tataatcgct
    39301 tcaatcaaga acaaaaagca gctatcacat atgatatgaa gaaacatctt cgaatcatag
    39361 caggagctgg gagcggcaaa acgcaaacaa tctgtgcaaa agctgtttat ctgatgacgc
    39421 aaaaacaagt agacgaagaa cgcatactaa tgatcacttt tacaaggaac gctgcaaatg
    39481 aactaaaaaa acgagtagat aatttcagcc agagaaaaac cgctgtccat atcggaacat
    39541 tccatagtat cttttttagg atatacaatg aaatttgtcg aaaatttcct gaagtagcaa
    39601 tgcaaggaat acaaggagac ttttcaaagg atactgcaca aaaagtgaat gctgttttgc
    39661 aacagctgat acgtaaatat aatctttata tatttgatca atatggagaa aaaacgattg
    39721 cttctcggtt agactattgg cagaatatga acctttcagt agaagaaatg gttcagttag
    39781 ttaaagaaaa atatgattcc attgataaga atgcacgaca gccgatatca gaacgactgt
    39841 atggattgct cacggaactc caagaacaaa aaagaagcca gcaattgcta gagttcaatg
    39901 atgtactcca aaatctgaaa agcgctttgg agaatgagga gatccagcat tatatcggcc
    39961 aaaaatatga ttatctattc attgatgaat ttcaagatac taatccactt caatgggaaa
    40021 tcgtgaaacg gatgacaaag gaaaacagga tcaagttgat tgttgttgga gatgatgatc
    40081 agagtatcta tggattcaga ggatcagagc cagcatacat caagaacttt gaaaaagaat
    40141 atcctaccaa aactcttttc ttattaacta attatcgttc tcgggcagct attgtccaag
    40201 gagcaaatag attgatcagc tataataaaa atgatcggat accaaaggcg atgattccag
    40261 cacaaaaaga agcaggtgtt atggaagcct atttgttttc tgatactaaa gcagaaagtc
    40321 agtggctaat caaacaaatt cagacattta ttcaaaaaaa tgggaaatat aaggaatcaa
    40381 tcatattata ccgatcagct tcacaaacgc agcagcttgt ccaatctctg ctgaaaacga
    40441 atattccttt tgtactggaa gcagatagtc catatgaagg tatctttggt atcaagtctt
    40501 tccaacattt ctatcaaaaa attgttcatt ggcaaacagc actgaatctg caaaagaaaa
    40561 atcaggccta ccagcaattg ctccggcagc tgatggcaga ctgctacctg aaaaaaagtg
    40621 aatgcgatca atacttttct cctaaatatc aaaatatatc cgttgcagat tatattttgt
    40681 cgataagccc caatttaaaa tcgaaatctg cagaaatccg agagtttgag gaagcgttgc
    40741 gtaaaacaga ccagcatcaa gaaatctatt cgcttgttca aagctatctt catctgccac
    40801 gtatagctaa ggaaatcgac cagagtgatc aagaatggat acgagaagaa gtaaagcagc
    40861 atgctacttt cagaagactc caagccttat cgcaagaaac ccaagcgaca gctaaagaat
    40921 taaaaacccg cttgattgct tacagacaag gaaaacttga tgcactatgt atccagagca
    40981 ttcacaaaag taaaggtctt agttaccgaa atgtcttttt gattggttgt aacgaaggaa
    41041 gtttgcctta taacggagcg acagaaaaga aagtaatcga ctttaatgaa ataaaagcag
    41101 aaccagtaac gacgatagaa gaagaacgaa gactatttta tgttgcgatg actagagcaa
    41161 gaaatcgtct gtatctatgt gtacctcaaa tgaaaaattc aagaaaattg aaagtatcga
    41221 gatttatcaa agaaaccggg agtcgtgtga aaaaaggaaa gtgata
//
LOCUS       DAFBSV010000013        41116 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.013, whole genome shotgun sequence.
ACCESSION   DAFBSV010000013 DAFBSV010000000
VERSION     DAFBSV010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41116
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.013"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(66..686)
                     /locus_tag="LLB18_000708"
     CDS             complement(66..686)
                     /locus_tag="LLB18_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HBK5243731.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(878..1174)
                     /locus_tag="LLB18_000709"
     CDS             complement(878..1174)
                     /locus_tag="LLB18_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBK5243732.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            1378..2028
                     /locus_tag="LLB18_000710"
     CDS             1378..2028
                     /locus_tag="LLB18_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBK5243733.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            2044..3771
                     /locus_tag="LLB18_000711"
     CDS             2044..3771
                     /locus_tag="LLB18_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5243734.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            3768..5660
                     /locus_tag="LLB18_000712"
     CDS             3768..5660
                     /locus_tag="LLB18_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5243735.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            6364..7233
                     /locus_tag="LLB18_000713"
     CDS             6364..7233
                     /locus_tag="LLB18_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HBK5243736.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            7442..8467
                     /locus_tag="LLB18_000714"
     CDS             7442..8467
                     /locus_tag="LLB18_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBK5243737.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            8506..9456
                     /gene="manA"
                     /locus_tag="LLB18_000715"
     CDS             8506..9456
                     /gene="manA"
                     /locus_tag="LLB18_000715"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBK5243738.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            9550..11253
                     /locus_tag="LLB18_000716"
     CDS             9550..11253
                     /locus_tag="LLB18_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK5243739.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            11255..13288
                     /locus_tag="LLB18_000717"
     CDS             11255..13288
                     /locus_tag="LLB18_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBK5243740.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            13299..13739
                     /locus_tag="LLB18_000718"
     CDS             13299..13739
                     /locus_tag="LLB18_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK5243741.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(13939..15066)
                     /locus_tag="LLB18_000719"
     CDS             complement(13939..15066)
                     /locus_tag="LLB18_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5243742.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(15069..15746)
                     /locus_tag="LLB18_000720"
     CDS             complement(15069..15746)
                     /locus_tag="LLB18_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5243743.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            16010..17776
                     /locus_tag="LLB18_000721"
     CDS             16010..17776
                     /locus_tag="LLB18_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HBK5243744.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            17791..18228
                     /locus_tag="LLB18_000722"
     CDS             17791..18228
                     /locus_tag="LLB18_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK5243745.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            18241..19392
                     /locus_tag="LLB18_000723"
     CDS             18241..19392
                     /locus_tag="LLB18_000723"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBK5243746.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(19454..20152)
                     /locus_tag="LLB18_000724"
     CDS             complement(19454..20152)
                     /locus_tag="LLB18_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HBK5243747.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(20145..21497)
                     /locus_tag="LLB18_000725"
     CDS             complement(20145..21497)
                     /locus_tag="LLB18_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HBK5243748.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLEYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(21720..23120)
                     /locus_tag="LLB18_000726"
     CDS             complement(21720..23120)
                     /locus_tag="LLB18_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HBK5243749.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            23281..24018
                     /locus_tag="LLB18_000727"
     CDS             23281..24018
                     /locus_tag="LLB18_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HBK5243750.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            24143..24622
                     /locus_tag="LLB18_000728"
     CDS             24143..24622
                     /locus_tag="LLB18_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HBK5243751.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            24619..25386
                     /locus_tag="LLB18_000729"
     CDS             24619..25386
                     /locus_tag="LLB18_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243752.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            25616..26185
                     /gene="lepB"
                     /locus_tag="LLB18_000730"
     CDS             25616..26185
                     /gene="lepB"
                     /locus_tag="LLB18_000730"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBK5243753.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(26289..26891)
                     /locus_tag="LLB18_000731"
     CDS             complement(26289..26891)
                     /locus_tag="LLB18_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBK5243754.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            26997..27466
                     /locus_tag="LLB18_000732"
                     /pseudo
     CDS             26997..27466
                     /locus_tag="LLB18_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            27572..28156
                     /locus_tag="LLB18_000733"
     CDS             27572..28156
                     /locus_tag="LLB18_000733"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBK5243755.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            28159..29232
                     /gene="prfA"
                     /locus_tag="LLB18_000734"
     CDS             28159..29232
                     /gene="prfA"
                     /locus_tag="LLB18_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBK5243756.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            29225..30064
                     /gene="prmC"
                     /locus_tag="LLB18_000735"
     CDS             29225..30064
                     /gene="prmC"
                     /locus_tag="LLB18_000735"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBK5243757.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            30057..30236
                     /locus_tag="LLB18_000736"
     CDS             30057..30236
                     /locus_tag="LLB18_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243758.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            30258..31283
                     /locus_tag="LLB18_000737"
     CDS             30258..31283
                     /locus_tag="LLB18_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBK5243759.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            31458..32702
                     /locus_tag="LLB18_000738"
     CDS             31458..32702
                     /locus_tag="LLB18_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBK5243760.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            32855..33802
                     /locus_tag="LLB18_000739"
     CDS             32855..33802
                     /locus_tag="LLB18_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK5243761.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            33936..34565
                     /gene="upp"
                     /locus_tag="LLB18_000740"
     CDS             33936..34565
                     /gene="upp"
                     /locus_tag="LLB18_000740"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBK5243762.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(34704..34946)
                     /locus_tag="LLB18_000741"
     CDS             complement(34704..34946)
                     /locus_tag="LLB18_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243763.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            35067..35139
                     /locus_tag="LLB18_000742"
     tRNA            35067..35139
                     /locus_tag="LLB18_000742"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35100..35102,aa:Thr,seq:cgt)
     gene            complement(35258..35896)
                     /locus_tag="LLB18_000743"
     CDS             complement(35258..35896)
                     /locus_tag="LLB18_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBK5243764.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(36019..36651)
                     /locus_tag="LLB18_000744"
     CDS             complement(36019..36651)
                     /locus_tag="LLB18_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBK5243765.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            37002..37301
                     /locus_tag="LLB18_000745"
     CDS             37002..37301
                     /locus_tag="LLB18_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBK5243766.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            37796..39961
                     /gene="acm"
                     /locus_tag="LLB18_000746"
     CDS             37796..39961
                     /gene="acm"
                     /locus_tag="LLB18_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HBK5243767.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(40233..40718)
                     /locus_tag="LLB18_000747"
     CDS             complement(40233..40718)
                     /locus_tag="LLB18_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBK5243768.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    40808..41042
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT        14001 a         7137 c         8269 g        11709 t
ORIGIN      
        1 caaggcacaa atgctgcttt gaagattttt tcctctgtct cttttgtatg catttatctc
       61 aatttttaaa atgatttacc taaagcagca gctttatcta atgcattttg catcaactca
      121 tctgcacggt cagggtcata atcgattcct tcgatgaata gctgatctac ttgatcgatg
      181 cctacaaagt ttaaaatacc ttttacatat tgagaggcaa agtcttgtcc gttgtataca
      241 ccgccattag attggatgtg cagtgctttt ttacctgtca ctaatccttc tggcccgttt
      301 tctgtatagc ggaacgtttt tccagctaca ttgacggtat cgaaccaagc ttttaatttt
      361 gttgggatat ttagattcca taaggcgttt gcgataacga ttttatcagc agcaaggaac
      421 tgatcagtca attcattgaa acgagcaatt ttttgttgtt gactttctga taaggaagtg
      481 aattctgcac cagcacgtaa tgcttcccaa cctgataata attcttcatc gatttccgga
      541 atatcatcgc gataaagttc caaaacagtc acttcatcat ctggatgatt ttctttataa
      601 cttgttaaaa aagacgtcaa tgccttaact gtgcgcgatt cttctgcagt taggggatga
      661 cctttgacta ctaaaacaga tgccatatgc ttaccttctc cttttattgc tatgattgtt
      721 ataactatga ctaacaaaat cagtttactc gaaaaagaaa aggctatcaa gtcatattga
      781 taaggttgaa gaataaataa ctaaaaaaag acagggtata aaagaggctg tgacacgatt
      841 ttttgtcaca gcctcttttg aatctaacaa gcaatattca agcaacactc gactgaagag
      901 cttccatccc accaatgata taaacagcac gaaaaccatt agcagtaagt tgatcggcta
      961 atgcttctga tcgcctgcct gtatagctta gaatataata aagtttcttt ggatctagat
     1021 tttttaattg tcttggcaag atagcagcgg ggatagaaag cgagtggctt aagtggtttt
     1081 ttgtgtaatc taaggtattt cttgtatcta aaacgatgct gtcagcatcg agaggcaatt
     1141 tattgaagtc ttggacacta attgattggg ccatttatct catcctttgt ttagtatgtg
     1201 gctattttaa tgggcaactc tcattaattc aaatggaagg attcctctta tcactttttt
     1261 aatgtatcgg atgataatga aaaaaactat gcaaatgtct tgcaaaacag gtaggaggtg
     1321 ttataatgac atagcgtcat atgacaatgt gtcatcttga aagaaaggag aatccatatg
     1381 ccgacacaga catttttcca tttgcctaaa gaaaaacaaa aaagactaat cgaggctgcg
     1441 agaatcgagt tttctagagt acccttaaaa gaagcttcga ttgctaatat cgtcaaatta
     1501 gcggatatcc ctagaggcag tttctatcag tattttgaag ataaagagga tctttatttt
     1561 tattactttg agacaatgag acgtgacagc tctaaagata tgttacaact aatgaaagaa
     1621 tccgatggtg atctattcaa aggattcgaa tcctattttt ctaaaatgat ttatgagatt
     1681 ttggaaggcg agaatgcttc tttttatcgt aacttgttta tgaacatgga ttaccgtgcc
     1741 tcaagaaaag tcgctcctca tacgagtcgc caaaaaacgc ctcacgatcc acataaagaa
     1801 cacaaacaag atgcaaaaga gttgcttgaa ttgatcgatc ggacgaagct gaaagtaaaa
     1861 aatgatcatg aattggaatt actgatccaa ttagtgatga atactgtatt tacaacaatt
     1921 gcgcattcgt atcgcttatt ttcaacatct gaagattact cagtagagca agcaatcagt
     1981 gaattcaatt tgaaactttc ttggctgaaa aacggagtat ataaatagaa agaagggaac
     2041 tagatgctaa aaatcgtaaa acggatctcc ttgacttcag caattgcagc tgcagttttc
     2101 atggtgatcc aagtactggc agatttatat ttgccgacac ttacctccaa tattattgat
     2161 aaaggggtag cgcaaggaga tgtcgattat atttggcata caggttttgt gatgatcggc
     2221 ttttctttga tcagtatctt agctgctatc gcaaatacat tttttgctac tcgtgaatca
     2281 cagaaactgg gtaagcaatt gcgtacggat gtctataaaa aatcagagag tctgacaaaa
     2341 gatgcgtttg ataaatatgg aacggcctct ttgatcacaa gaacgaccaa tgatgtgact
     2401 caaatccaaa tggttacaca aatgttttta cgtatgatga tcaatgcacc aatcacgttg
     2461 attggcgcga gcatacttgc ttatcaaaaa gatcatcagt tgacaaaaat cttcttagtt
     2521 gtcatcccag taatgattat tttgatcggc ggaatcatgt actttgctgt tccattattc
     2581 aaaagtatgc aaaagaaaac tgaccgttta aacctggtat ttcgagaagg attgacaggg
     2641 gtcagagtga ttcgagcatt cgataagaca cgctttgaag aaaatcgttt tgatttagcg
     2701 aataaagatt atacaaatac ggcaatcaaa gttaatacga tcgtcgcatt gatgatgcca
     2761 atgatgacat tgatcatgag cggtacaaac gtagcaatca cttggtttgg tggacactac
     2821 atagcagata tgactttgga agtcggtaat ctgattgcat ttatgactta tgcgatgcag
     2881 atcttgatca gctttatgat gctttccgct atttttatca tggtgcctcg tgcacaagct
     2941 tcagctgacc gtattaatga agtgttggat gaaaaaatcg gtatccatga ccctgaaaat
     3001 cctaaaacag tttcttttgc tggaaaaaac gcaacattgg ccttcaatca tgtcaattat
     3061 cgatatcatg gagcagaaaa acttgcattg gaagatattg atttccaagc caagtcgggc
     3121 gagatcgtcg caatcatagg ggggactggt tcaggtaaaa cgaccttagt caatttgatc
     3181 cctcgattat atgacatcga atctggttcg atccaaataa atggaacgga cattagtgac
     3241 atgactcaat ataatttgcg agaattaatg ggctttgttc ctcaaaaagc agttctgttc
     3301 tctggaacga tccgagacaa tatgcagtat ggtaagccgg atgcaacaga tgaaatgatt
     3361 tggaaagcat tagaaatcgc acaagctaaa gattttgttt cagagatgga agatggctta
     3421 gatagccatg tggaacaagg aggaggaaac ttctctggtg gacaaagaca gcgtctggca
     3481 attgcacggg cattagtcaa aacagcagat atctatgtgt ttgatgattc cttctcagcg
     3541 ttggatttca aaacggatgc caatcttcgc caagcattga aaacgaatat gaaagaaagt
     3601 atcaccgttt tagttgctca acgagtaagt acagtaatgg atgcagatat gatccttgtg
     3661 ctagatgaag gaaaactggt tggcaaagga acacatgaag aactattagc aacaaacgaa
     3721 acttatcaag aaatcgttca ttcacaacta agagaggagg acttagcatg agtaaaacaa
     3781 acacacgtcc ctctcatgga ccagcaggcg gtccaggaca tggtggacct ggcagaaatc
     3841 tcggtgtaaa aggtgaaaag cctaaaaatt tctggggaac ggtacgccga ttgtttggct
     3901 atatgtctaa acgtatggtt gcgatcatcg ctgtatttgt actagcaata gcagccgtga
     3961 tcttccaaat ccaaacacca aaggtcttgg ggaaagcaac cacagaaata ttcaaaggtg
     4021 taatggctgg cgctcaacag atgcaacaag gccaacaagt aacaaaattt ccgatagact
     4081 ttgataaaat cgcgcagatc attgcgacag taatcgtgat gtatttgatt tctgctgtat
     4141 tcaacttttt acagcaattt attatgacac gtgtttccca acgaacagtt tatgaattac
     4201 gtcatgattt ggaagccaaa atgaatcgtg taccgatttc ctattatgat acacatacaa
     4261 atggggatat catgtctcga gcaatcaatg atatggataa catcgcaagc acgctgcagc
     4321 aaaatttgac tcaatttgta actagtgcag tcacattgat tggggtcatc gtgatgatgc
     4381 tttcaatcag ctggcaattg acgttagtcg cgttattgat gatcccttta agcttgatca
     4441 tcgtgatgat cgtagcgccg aaatcacaag tgtttttcgc agatcagcaa aaaagtttag
     4501 gtttattgaa taaccaagta gaagaaacat atggtggtca taccattgtt aaaacattca
     4561 atcatactga aaaagaccag gaagtatttg aaaaagaaaa tcagaatctg tatgccgctg
     4621 gttggaaagc tcaatttatt tcggcaatca tcatgccgtt gatgaatttc gttaaaaatc
     4681 taggctatgt gttcgtcgct gtactaggcg gagtaaaagt tgcaaatggg aacatgacat
     4741 taggggatgt tcaagcgttc ttgcaatata caacacagtt ctctcaacca atcactcaac
     4801 ttgcaagttt gatgaacact atccaatcaa cagttgcttc agccgaacgg gtatttgaag
     4861 tgttggatga agaagagatg tccaatgaaa aatctggcct tccagaagaa aaagatacac
     4921 catacaaagt tcgttttgaa aatgttcaat tcggctacac accagataac ttgctaatga
     4981 ctgattttaa cttggatgtc aaacctggtg agatggtcgc tattgtaggt ccgactggtg
     5041 cagggaagac gacactgatc aaccttcttg aacggttcta cgatgtttct ggaggtagta
     5101 ttcgttacga tggtgtagat acccgtgatc tttcacgtga tgaattgcgc gcacagtttt
     5161 caatggtact gcaagatact tggctgttta caggaagtat ctatgacaat atcaaatatg
     5221 ggaacgacga tgcaacagac gaacaaatca ttgaggctgc taaagctgct cacgtagacg
     5281 attttgttcg taaattgcca gaaggatata acactgtatt aaacgaggat gcaagcaata
     5341 tttcgcaagg gcagcgtcag ctaatcacaa ttgcgcgggc attcttagca aatccagatg
     5401 tcctgatcct tgatgaagca acatctagtg tagatacacg aacagaaata ctgattcaaa
     5461 aagcgatgaa ccgcctattg gaaaaccgga caagtttcgt tgttgctcac cgcttgtcta
     5521 caatacgcga tgcagacaac attattgtga tgaatcatgg ttcgatcgta gaaacaggaa
     5581 accacgatac attgatggaa aaagacggat tctatgcaga tctttataac agtcagtttt
     5641 ctgaagaaga agcttcatag aatagtacaa atttattatt ttttttaggg gctgtgacaa
     5701 aagtcgtgtc acagtccctt tttccgaata aacggtgttc aatcagctgt ccttcggtat
     5761 tagctcaaaa aacggcaaaa tatgagaagc tatttttccg ttttgtatct ctaatactca
     5821 ggtcaaaccg ctgattttac aacctcttcc ttaaacggtg ttctcctgcc aactcctcgg
     5881 tcacaagtca caatagtcaa caaacctgag aagctgtttt ttgaaattgc tccttgtgac
     5941 tcggagttaa acggcaggct cacaacctct tggtaaacgg tgttcaaaag ccagtttctc
     6001 ggtattaagc caaatttatg caaaaatgta gaaagccatt ttcacaaaat ttttcttact
     6061 actcgaaact aagcgacttt ttcacaacct cttccttaaa cggtgttcaa aagcttgcat
     6121 ctgcggtaat aagcccaacc aaacgaaaaa taggaggagc tatttttgtt tggctgttct
     6181 tattacttga tgcagaacag ctttttcaca acctcttttt ataagagttt ttactcatta
     6241 atttacaaaa aacaagcaaa atgcgaattt tctcacattt tttttaacaa aatcaaagtt
     6301 attgcttgaa agaagaagaa tccatcgtta aaataaagct tgacgtagag gggagcaaga
     6361 aatatgaaag attttcaatt gggggctgcc acctatttaa aaagtgtagc cattcgggtg
     6421 aaagaccgag ataaaatgat tgatttttac aagaacgttg ttggctttga tttgaaaaga
     6481 gaagaaaacg aattagccat tttaggaaca gaagaagctg gaagtgaaat gttgctgctg
     6541 gaagaaagtc ctagagcgaa tgatcacatg ggggtgatca aaaagctgaa ccgtttttca
     6601 ttgattatcc ctagcacaga agaaatggca gatatccttt gtcgtatccg taaaatgaat
     6661 tatccaatca aagaagcttt agaagatcat ggacgtatgg ggattttgct cgtagaccca
     6721 gaagagaatg aattggaaat ttaccatgaa gagaataaga acgaccaaag agaaattcca
     6781 gaaacaatgg atcaagaagc attattaaga aaatctgaag aaaaattcag taaactatca
     6841 acaggttctt attttgaaaa aatccattta aatgttacta acttaacaaa agaacgccaa
     6901 tttcttaatc atgtacttgg tttgaaggta cataatgaag aagagggcat ccatgtattg
     6961 aatgaaggag atttccatgt tggtttgaca gaagctagcg gaggcgcaat tgatttgcct
     7021 acagatgaag tgattggact tgattttctg aaattcatga tcgatactga aagcatggaa
     7081 ggactgattg ctcacttgca gcaactatca gttgatttct tcttagacaa aaagcacaca
     7141 gtactcacaa tctatgatgc tataggaatc gaatggtggt tcgtcagtga gccaaaagaa
     7201 aagaataaaa ctgacattcg atgcgacgct taactttttc tttcttaacg attgtcgcat
     7261 gtctcgtcat tttatgaacg gtcatactat cgcttattct agagatagaa agagaaaata
     7321 gtataccggg ggaaactgcg cggtttttcg cgcagttttt ttgtgtaaaa aaggttgatt
     7381 cctcatagat taagctttaa gcttggactg taagaatctg atagaaaagc aggagaaaaa
     7441 gatgtatcca cacacgaaac agcttatttt gaaaaagatg gaagaaggat tttatccagg
     7501 tgtagcagtc gccttcataa aagaaaatca agtagaaaca tttacagccg gctttgccca
     7561 agtcgttcct gaaaagcagc tgatgacaga agatctgttg tttgatgcag cctcactgac
     7621 gaaagtcgtt gcaaccactt cattagtttt acgtctatta gaagatggaa agatagaact
     7681 cgatcaaccg cttcataaat atcttcctga atttgaaaat cagacaatca ctttgcgtca
     7741 tttactgaca catacttctg atatcaaaac atggatacca aacagagata agctatctca
     7801 ggaagaattg atcgccgctt atttgaagct agaaccaggt gagcaactag gaaaagaagt
     7861 aaaatataca gatgccggta cgattcttct tgggttgatg ctagaggaaa tttaccaaga
     7921 aactgcagtg gaaatctttc aagaacaagt attggaacca ttaggaatga tgaacagctt
     7981 atttcttcct tttccttcca aaaaaatcgt tcccacagaa caactgcctt cgggtgaggt
     8041 tttgcgtgga caaactcatg atccgaaagc aagagttttg gctgaacatg caggtaacgc
     8101 gggtctcttt attgatttga aagacagcat tacttttgtc caaatgtatt tgaacaaggg
     8161 aaaaatccgt aatggtcgtt ttttagaaga agagacgatt gattctttac tgcaagatca
     8221 aacaccgaaa aaaaatggct atcgttcttt aggatgggac ttaaaaaagg atgtagaaga
     8281 cggtcatgcg attctttttc atactggtta tacaggtacg tttttcttga ttgatataaa
     8341 aacacaagaa gcgttgatat ttttgtcaaa tcgcgtacat cctgtcgatc atcgtgcgga
     8401 gtatctcata tgtcgagatg aaattgttga aaactttttg aaagagaaag cggtattacc
     8461 gaaataatgc tataatagct atgaaaaatg agaggagttt gaattatgca ggaacctatg
     8521 tttttaaaac cagtttttca agaaaaaatt tggggaggaa gtcgtttacg ttcagtcttt
     8581 ggttttgata tccctaacga taaaatcgga gaagattggg cgatcagtgc gcatcctcat
     8641 ggtgtcagtg tagtagaaaa tggcgaattc aaagggaaaa gattagatga actatggtca
     8701 gaacacaagg aattgtttgg ccatccttca gaaccagtgt ttccattatt gatcaagatc
     8761 ttagacgcag aagatgatct atctgtacaa gtacatccag atgatgccta tgggatgaaa
     8821 catgaaggtg aattaggaaa aactgaatgc tggtatatca tcgatgctga acctggtgca
     8881 gaaatcatct atggtcatca tgcaaagaca agagaagaac tagctgagat gatcaaagat
     8941 gggcgctggg atgacctttt gaagaaagta ccagttaaaa aaggtgattt cttttatgta
     9001 ccaagcggaa cgatccatgc tattggtaaa ggaatcatga ttttagaaac acagcaaagt
     9061 tctgacacga cttaccgcgt gtatgactac gacagaaaag atgcgcaagg acaaacaaga
     9121 gagctgcata tccaacaatc gatcgatgta acaactgtcc ctgcgaaaac accagaatta
     9181 caaatcaaag aagtccgaaa agggaattca tcgatcgtca cttatttaga aactgagttt
     9241 ttcaatgtat atgagtggga tattaaagga atcacatctt tcaaaaaaca agccccttat
     9301 acattgatga cggtaatcga aggagcagga gaccttgtcg ttgacggaaa aacatatcca
     9361 ttagaaaaag gaacaagctg tattattcca aatggcgttt ctgagtgggc ggtccaaggt
     9421 gaactagcaa tcattgcgtc tgaaccaggc aaatagttcc cagatagctg aaagcagcag
     9481 acggtttttc gtttgctgct ttttctacat aaaatccgtc catcaataaa tagaagtctg
     9541 gtgaaaaaga tggaatacaa atggaaagca aacaacagca gtcgcgtgtc tatgaaacaa
     9601 ctgagaaaag ctggacatca cctaaatgaa atgatcatgc caaatctaag tctgtttatc
     9661 gcttggggaa tcttgtcatt agcaacaaaa ggtgtgtctg gcgatttgca caccacatta
     9721 gaagaggtat gccattggat gatccagctg cttttaccca tcttgatcag ttattcaggc
     9781 gggaaatcgg tagggggaca aaaaggggca gtcgccggtg caattgcttc tttagggttg
     9841 atcgctcgtt ccaatgctcc acaaatcgta ggagcgatga ttatcgggcc gcttgccggc
     9901 atcgtatatg aacaatttgt ttctagattc catgtgaaat tcaaggctgg atatgaaatg
     9961 cttgtcagca acctactagt aggactgact ggtagcgtta tttgtataat tggaatcgtt
    10021 tttattgaac cagttttaaa tagtgttcac ttgttgctcg cctccgttgt gtcttggcta
    10081 gtcacaatga atctgttacc acttgtcagt ctgatcttag aacctctaaa agtactattt
    10141 ttcaataatg caatcaatca tggtgtattg acacctttag gaatcgaatt ctcacaaaca
    10201 gtcgggtact cttccttatt tttgatggag gcaaatcctg gacctggttt agggatctta
    10261 ctttctatcc tttgttttgc agaaaaacag gaaaaagtaa atgcgagtgg agcattgatg
    10321 atccatgcga ttggcgggat tcacgaaatc tattttccat ttgtcttgct gcgaccgtat
    10381 ctatttttag ctgtaatggc tggtggggca agcggcacgt tgatatttca atggttagat
    10441 acgggattag ctgcacctgt atcgcctggg tcactactcg tgatttttgc caatgcgcct
    10501 tatccacaac tagctggggt aagtataggg atagcaatca gtacatttgt gaccttcatt
    10561 tgtgcagcga tactattgaa attaccaaat aaagaaaaag agaacaaaac ggtcaaagaa
    10621 aggggagaaa tcttggaacc atctatcatt cattccgtca tttttgcttg cgactcaggt
    10681 atgggatcaa gtgctatggg agccgccctg ctgaaaaaga aattagcagc agaaaaaatc
    10741 gatctttctg tcggatacag ctctatctat gaattgaata accaagtaaa tcagctggtt
    10801 atcgtgcaac atgaactagc gggtcttgca agagaaaaag tacctcaaag tcaaatctat
    10861 gtactggatc actttttgga aacagatatc ttgctgtcac gaataaaaga agcgatccaa
    10921 tttccaaagc gggaagaaaa aaaagagata gcagatatca cagaacaaaa aacgtcgcct
    10981 gctaatattg tatttttgta taaaaacaac agacgcggct cacaaactat gggcatgacg
    11041 attttaagtc aattagcaaa aaaagcgaaa aaacagtttg ttatctcaaa agaatcaata
    11101 gaaaaaatca aaatccaaga agaaacgatt tatatcgcac aaagagaact agctgtaact
    11161 gaacagctag aagaaaagat ccctcggcta gttctagttg aacattgggt agctacgaat
    11221 gaatacgaaa aactcgtgaa gggagaaata taagatgtat ttatcgccca gagaaaaaca
    11281 attattagca gaatttctca gtagcccgtc acctgtatct atccaaaaaa tgatgaattt
    11341 attgaaggtc agtaaacgga ctatttaccg cgaattagat aatcttgaag tctcattgaa
    11401 atcggtaaat gcttctttga aaaaagcagc tagaggctca tttgtcattg aggcatcaga
    11461 agaagtatta gagcaattaa aagaaaatac agatgggaaa agtaatgact tatccactgc
    11521 taaacgacaa cacgcgattt tagccgagtt gttactgacg acagagccgt tgagtcttgc
    11581 tcatttcatg gaatcatatc gcatcagtaa taccactttt tatgcagata tcaaacagtt
    11641 ggaagaaagt attcgccaac tgcctttgga aatcattcgg aaccagggat acgagatcga
    11701 aggaccggaa aaataccgcc ggcttctgac agcgaatgta ttagaattag aaatcaatga
    11761 atatgaactt tttcatagta tttctttcga tgcatcactg aattattttt ttagattcgt
    11821 tgatccgcaa catctatctc ttgcacgcaa agtaatcggg gaagaattga tccaaaaaaa
    11881 gaccaatcta agtgatagaa agcttgaaca tttggttttg atgctgacat tgacgatgga
    11941 gcgtgtgacg aaaaatcatt tactgacaaa tgagacatat aatagtctgg caaacaaaga
    12001 attactacag acagctaaac gattgttttc acggatcgct tctgagacaa aacaacttta
    12061 tccagtaaat gagatcgtct tttttgcagg attattaaat gacttcacga actcatttga
    12121 tcagaatttc tttgaagaga cgttcgatac acagcttgct tatttagtaa aacaactgat
    12181 tcaagaagta agtgaagaga cgaatgtcca tttttatgaa gatgaaactt tgtacaaaat
    12241 gctgttgact catttatctg gtgtgttttc aagagccgtt ttacaagaag agacactgac
    12301 caatccgatt ttagaaaaaa tcatggttca atacgaggaa gttgcgaatg caatccgtaa
    12361 agcagtagag cggatttttc aagaaaaaaa attatccgaa gaagagatcg cttatatggt
    12421 ccttcatttt gcgaattcat tggaacgaag tccgaaagaa agcaatatca gtattgcagg
    12481 attttcgcca agtggattag cttctactag catgttggaa ctacgattga aaaggtattt
    12541 tcccttcatc caacaaattc atttctatcg gattgctgat ttaaaaaaaa tcgatttaca
    12601 agaagaatat gatgttgtta tttctacatc tattttacca ggatacggtg gaaaatatat
    12661 tttagtctcc ccgctactgc tagaagatga agtcaagcag ctaaaagaag ctttttcgca
    12721 tattgagaag aaaaaaaggc aaaaaattac gtataacagc aataacgagt ggatgataga
    12781 agatacttat gaggaaacaa tgcatttcat ggatcaaatc aatcaattac tcggtcgttt
    12841 ttttatccaa gaactggata atcctgagac gatttccgaa acgattcgca gcttatttcc
    12901 ttattttcct gaaggactag taacggatga agaggtggtt catcgccggc tgcttaagcg
    12961 atatgaacaa gcacctatcg gtattcctca tacaaatatg gggttattcc atacatccag
    13021 ctcattgatt tctaaaccga tcttttgtat tttcaatttg aaacatccgt tgaccattga
    13081 agggatggat agacagccag tcgatttgtc ccgtatgtta gttatgctgg cgccttcgcc
    13141 aatccaagaa aaagacggga ttcttttagg aaagatcagt ggagcaatca tcatgaatga
    13201 cttgaacacc gagatcttcc gctcaggaaa taaagaaatc gtttatcagt tgttagcgaa
    13261 aatcctgatt gaagaaataa agaaatgaag gtgaaaagat gatacagcta ccagcagaaa
    13321 aaatattgct cgatcaatcc tatcaaaatt ggaaagaagc gttgaccgag atcggccagt
    13381 ggatgaccca acaaggggga atcaaaccgg catatatcca atcaatgatc gaaagacaag
    13441 aaaaagcgag tgtctatatc gggaatttcg tagccttgcc acatgggact gacaaagatg
    13501 aagaagtagt agaagaagga atctatttag tccaagtgcc tgatggtgtg gactttggaa
    13561 caaaagagga accaaaaatc gcgacactct tatttgtagt ggctttaaaa aaagaacatc
    13621 agttagcggt gctccaagat ttagcctttt tctgttcaga catcgaccaa gtaatggcgc
    13681 tcagtgatgc ggaaaccatt gaagaagtcc aaatgatttt tgaacatgga catatataac
    13741 caatgttcac agtaaaaaaa gctgccttgc atcaagtaat aacttcaacc aagataaaaa
    13801 taagaggagc tatttttgtt gggaggttct tattactgcg gatgcaagct tttgaaaact
    13861 atttattcta gaaaaccgtt tatttgaaat aggggacggt gacaaggttt ttgtcaccgc
    13921 ccctattatt tttgtgtttt aatagctctt ttttatatag atagtgccca tacctatgaa
    13981 taataaaacg atactccata taccaagtgt caagatacca ttcatgaaag taacctgttc
    14041 tgaagctagt ggcgagaaaa tatctcctcc tatgatcaca ttttgaaaat caacataaga
    14101 agttggcaag taatgactga ttgattctat ccatccaatc gaagaaaaca agcgatactc
    14161 tgctaagaaa agacaaagaa gtgtacctaa aagattgact agagaatgtt caaataaagc
    14221 agatagaaga aaactgattg tacttaaaaa gagcacccac aacaacagga acagaaagct
    14281 ctggaaaaga tactcataca tcggcaggat tcgtatctcc tgaccaatga tcgttcctac
    14341 aggataacgg aagtctccca aaccattttt gattattact agtatagaga cgatcaaaaa
    14401 tggcatcacg agacttagca tagctgcacc ataataaatg gtaaaacgga tgctatgttt
    14461 ctttaccata ctatccggta atagattgac tagagagatt acctgctttc ttttttcata
    14521 agagatgatg gaagaaagaa acaaggcggt tatacataaa atcaaaaaac tagaaatcat
    14581 tcctgaaaaa atattttcgt agtaatttgc taaagagaga tgcgctggca agtcaaaaat
    14641 agaatatctt tggatctgat gttctttcat ataacggagc aactcgacac gtttttgttg
    14701 ttcaatgatt ggaattcctt gtctttgacc agaaatcagt cgatccagta tatctttttc
    14761 ataatgataa gttgcttcga ccatttgctg gacattccct gtgttttttg catgtaagat
    14821 tgcttcgatc agtttgttgc ttttctctaa actttccaca aattctttct cattctcatc
    14881 ttctttcaac gtttcaatca aacgttgcat ctcttcatag ttatgattca gttcatcgaa
    14941 ttctgtataa gcaagtttat gatcaaaaaa aagtgggaat gcaaagagca cgaccaacaa
    15001 tagaggaaat aaaaagttta ctttgttttt tagtaagaga ttgcgttcaa atgtaagtaa
    15061 agacatagtt acacctcata taatttacga taaatagcta aaatctcttc catatttgag
    15121 gattctgtga cgatttctcc attttttaga aaacatgctt tagaacaaat cgattggata
    15181 ttcgcgatag cgtgggaaga aagaagaatc gtcttcccct ctttctgcca ttgtctgatg
    15241 aggctattca agatatcaat acttcctggg tctaatccgt tcaacggttc atcgaataac
    15301 atgacagatg aatcactgat caagtaagca gcaagcaaga catgttgttt cattcctaga
    15361 gacatttttc caatcggcaa agtaaggtac tcagtcatct tcaatcgttg gaaaacagtt
    15421 tggcattcta ctttgctctg ccaatagtat ttgatcaaag tcaaataatc aacagccgat
    15481 agatagtcgg ataactgatt cgttgattct agaaaaaaga aagaccggcg ataatctgta
    15541 taagcagtag gagagatgtt gtgaagggac aattgatcat aagttgttgg cagcagttgg
    15601 gcaatgccat tcagcaaagt tgttttgcca aatccgttcg gggcaatcaa agcagctact
    15661 tctcctgatt ctactaaaag attcaattgt cgaatcacac gttttttacc acgtttcatg
    15721 ttcatgtttt tgatcagtaa tgtcatagat aggcctccaa tataaaattt aataacataa
    15781 tagaatggaa aacatctaaa ttaaatgcta acaaaagtta ttgtttgcat attataaaaa
    15841 aattaaaata acagttttat ttaaaattga agttttctga taccgaaatc tttttatttt
    15901 gctgacatac tcaaaccttt ggcacaaagt ttcgtgccaa agtacgacta tttctctttt
    15961 tagtaagcgg atacaattag agtatcaaaa ggagagaggg agagacaaaa tggaacggac
    16021 gattcccaaa aacaacattt cgctaaaagc gagggtacaa aaattaggca gtactttatc
    16081 aagcatggtc atgccaaata ttggagcact gattgcctgg ggtgtattaa cggctctatt
    16141 tatcccagat ggttatttac caaatgaggc tttcgctacc atggtaagcc caatgctaac
    16201 ttatctgatt cctttattga tcggttatac tggcggaaaa gtaattgctg gtgaccgcgg
    16261 atcagttgtt ggggcaattg caacgatggg tgtgattgtc ggaacagata ttccaatgat
    16321 gctaggcgcg atgatcatgg gacctcttgg tggatatgcc atcaagaaat ttgatcagct
    16381 attccaaaaa cggatcaaat ccggttttga aatgctagtc aataattttt cagcaggtct
    16441 tatcggtttt ggattagcgt tattaggttt ttctgcgatt ggtccagttg tcgatgcatt
    16501 gactcaagca atggcaaaag gtgtagagat cattttatct gcccatttga ttccattgac
    16561 aagtattttt attgaaccag caaaaatctt atttttgaat aatgcaatca atcatgggat
    16621 tttgacacca ttgggaactg aacaagtagc agaggctgga aaatctattc tattcttgct
    16681 tgaagcaaat cctggtccag gacttggcgt attacttgct tttactttgt ttggcaaagg
    16741 agcagcaaaa tcttcagcac caggagccat gatcattcac tttttaggcg ggatccatga
    16801 aatctatttt ccttacgtta tgatgaaacc gttattattc ttatcagtta taggcggagg
    16861 aatgtcagga agtttcattt tccaattgat ggatgctgga ctaagagcgc cagcttctcc
    16921 agggtcgatc attgcgattc tagcgatgac accgttcaat tcttaccttc ctgttatttt
    16981 gggcgtgatt gttgccgcag ctgtttcgtt tggtatttct gcagtaattt tgaaagcgga
    17041 tgcgaaagat acaaatgaag acttcgaaaa atctgttcaa gagacaaagg cagctaagca
    17101 agcttccaaa ggtgcccaag gtattcctca aggagctaca ttctctggcg tacaaaaaat
    17161 catttttgct tgtgatgcag gaatgggatc aagtgcgatg ggcgcttcga tcttgagaaa
    17221 aaaagtacag gaagcagact tgcctcaaac ggtgaccaat caagcaatca gccaactgac
    17281 agatgactcg aatacattga tcgttactca ggtcgaacta caagaaagag caaaacaaaa
    17341 agcaccgagc gcgcgttttg tctcagtaga aaactttttg aattcacctc gatatgatga
    17401 aatcattcaa gaattaagca gcaagcagaa aacatcagtt tctgaaattg agaatgagcc
    17461 agcagaagag tttctttcag caaacatcaa acaaatcaaa gagattctac ttgtccacga
    17521 tgatcgttcc ggatcagcaa caatggggat gaccgtgctc aaagatatat tagacaagaa
    17581 ccatttaact atcccgttaa gaaaagtcaa tatccaagat ttaaaagatg aacctgattc
    17641 actgatcgta gccaaagaaa gtttagcgga aaaagtacag atggctgcac ctcaatccat
    17701 tcatttatca gtcaacagca tggtcaatcc gcaaaaatac gaatcgattg cacaatattt
    17761 gaaacagaca gcttaaggga ggaaaacagc atgcaaagtt tgccattcga catgatcgag
    17821 ctcaatcgat cttttaaaac caaagaagaa gcgatccgct attgcggtca gatgcttgta
    17881 gaagcagggt gcgttgatga ggaatatatc gatgccatgg tagatagaga caaaatgtta
    17941 tctgtttata tggggaattt tatcgcgatt cctcatggaa cagatgaagc aaaaaaatat
    18001 gtgaaaaaat ccggcatctg tgtcgttcaa gtaccagatg gtgtagattt tggtaccgaa
    18061 gaagaagaaa agattgcgac tgttttgttc ggtattgcag gagtcggaga tgagcatttg
    18121 caacttgtac agcaaatcgc actttattgc agtgatatgg acaatgttgt ccagctagca
    18181 gacgcgctca gcaaagaaga agtaacggaa aatctagcaa ttgcttaagg agagagaaaa
    18241 atgagagcag tacattttgg tgcaggaaat atcggtcgag gatttattgg agaggttttg
    18301 gcagctaatg gatttgagat tactttcgta gatgtgaatc acacgatcat tgatgcttta
    18361 aatgaaagaa aagaatacga aatcgaatta gcagatgaat caaaagaaaa aatcactgta
    18421 aaaaatgtca aaggaatcaa caatcaaaca aatccagaaa aagtaatcca agaaatcgct
    18481 gaagcagatt tagttactac cgccattggc ccgaatatct taccttttat tgctgagttg
    18541 attgcaaaag gtatccaaga aagagaaaag gaaggaagca caacatcttt agatatcatt
    18601 gcctgtgaaa atatgattgg cggttcagca tttctagaaa aagaagtgta taaatatctt
    18661 ccggaaacat catttactga caaatatatc ggctttccaa atgcagcagt cgatcgaatc
    18721 gtcccattac aacaccatga agatccttta ttcgtccaag tggaaccttt caaagaatgg
    18781 gtcattgacg atagccaaag aaaaaataaa aaaatccaat taaaaggggt tttatatgta
    18841 gatgatctag aaccatatat cgaacgcaaa ctatttagtg tcaatactgg tcatgcgact
    18901 gtcgcttata caggtgcctt gttaggttac cagaccattg atgaagcaat gcaagatgcg
    18961 ttagttgtgg cacaattaaa atcagttttg caggaaacag gaagtttgct gattgccaaa
    19021 tgggggtttg atgcagagca gcatcatgcg tatattgaaa aaatcattca tcgcttccaa
    19081 aacaaaaata tctctgatgc gatcacacgt gtcgctcgga caccattacg taagttaggt
    19141 tatcaagaaa gatttacacg tccagtgaga gaactacaag aacataactt gacttgccca
    19201 catttgacgg caacaatggg gattattttt aattactatg atcctgaaga tgaacaaagc
    19261 cgtcaattgc atgaaatgaa gatccatgaa aacttggaac aattgattca agaagtcaca
    19321 ggaatcaatg atccgaaaac aatcgggaat atcaagcaaa acgtgaaccg ttatgccaag
    19381 caagtcgctt aaaataggat acgaaaaagg ggaatgtgac gaaatttttg tcacattccc
    19441 ctttttcgaa taactaggct gtttgtcctt caagataggg cagatccaat tctttaccgt
    19501 aacgttgttc taaagctagg cggatcaaac gagctgccag gttctcattt cttgcaagga
    19561 taggtccatg gaaataagaa ccgaagacat ttcggtaaat gacaccttca gattggtctt
    19621 caccattatt tccttgacct tgtaccactt tccccaaagg tcgttcacct tcacctaaga
    19681 aagtccgacc attgtggttt tcaaatccat aataagtttc attgaattct tcgttatgga
    19741 taacgatatc accgataaac cggttatttt cctgacttaa cgtgtagtga tccagtgcac
    19801 tgattccttg gatcttttct ccattagctc ccatgtagta gtgacctagc aattggtagc
    19861 caccacaaat ggctaacatg acgccatcat tttcgatata gttgatcaaa gaatctttct
    19921 ttttctggat gtcttttgaa atgattaatt gctcaaagtc ttgaccaccg ccaaagaaaa
    19981 ccaagtcata tttatcagca tcaaaaggtt catgtatact aacgatctcc gtatggcaag
    20041 aaacccccat tttttctgct atatatttca acatcaaaag gtttccgtta tcaccatatg
    20101 tgttcatcaa atttccataa aggtgggcga tattgagttc ataattagcc acggttcatt
    20161 cctcctttga taaatccttg agcagctagt tctttacgaa gctgcaatac agcagtgtaa
    20221 gtagctaaaa tatagacatg ctcagttggc aattctttga ttttttcgat tacttctggt
    20281 aattcttttg tttctgtcaa tttattttct ggaatcccgg caacttttag acgtaaagtc
    20341 atatctgtat gacggtctcc tccagaaata acagctggga tatccatatc ggcaaagttt
    20401 tcaaaattac catcccaaat ccagctgaca tcgattccgt ctgcgtaatt ggcatttaat
    20461 aaagccacta aagaaaatgg ataaggagct agaccaatca tatcgattac ttgattgata
    20521 cctacaggat ttttgacaag tactaatgta cattttttcc cattgatatt gatgacttct
    20581 tgtcggccga atactttctc gtcatattct aaaccttgtt tgattttatc aggatcgaca
    20641 ttgaagtact ctgccactgc agtagctgct aaagcattgt agacattata cataccgcca
    20701 acttcgattc cgtattcatg accatcgatc acgaaatctg ctgacacatt gtccatccgt
    20761 accatatcag ttaatcgata atccaattca ggacgtttga agtcacaatt tggacagtaa
    20821 tatttcccta agtttgcata agtgatcatt ttataatgca agatgtgatg acaatttgga
    20881 cataagacac cgtctgtatt gtaatgagcc atttgttcac gatcttcttc atggtcaaag
    20941 ccataatatt ttctaggatt gactgtttcg atagaattga agattggtga atcaccgtta
    21001 ctgataatcg ttgcatttgg tgactttgcg gcaccgtcta caatcatttt ataggtcgta
    21061 tagatttctc cataccgatc catttgatca cggaaaatat ttgtaaataa gaacagttct
    21121 ggtttcatat attctgtgac tttgctcaaa cttgcttcat ctatttctag gacagcaaac
    21181 tttttctgtc ctttttttgg ttttgcctgc aagaaagtcg atacaattcc ctgtaccata
    21241 ttcgcaccag tagggttggt tagaacttca tcgaattgct ggcgcaaaat attgactgtt
    21301 aaagcggtag tcaatgtttt accgtttgtt ccggtgacaa cgacgacttg gtagtctttt
    21361 gccaaactat ctagtatatg tggatcgact ttcagcgcta gtttacctgg taaacttgat
    21421 ccgcctttaa aaaaagtttt taatgcccat tgcgacgttt ttccaactgc aatcgcaaaa
    21481 tgactgcgta ttcccattat gtaacctcca aaaacgattt gctgacgaat aaattcaact
    21541 aatcatacca tatgttgaaa aaaaggttaa attgcttttc ttattcttaa gaaaaggtta
    21601 cggctgaaag tgcatgaaat cggacaaaat cgcatgattt aacaaaaaaa cagcttgaaa
    21661 caaaatgatt gtttcaagct gctgtgattt tattattccc tcttacctat attcccattt
    21721 taaccgataa taattttctc gcttggatat tcatagccta gatctcgtgt ttcttttggc
    21781 acgaataaca tcaatgtata tagcattccg atccgcccaa taaacatcag tgtagcaatc
    21841 gtgattttgc ccacaacaga caagtctccg gtaatcccta aagataaacc agttgttcca
    21901 aacgcagaag ttacttcgat gatgatcgag atcagcgttt gttcttctgt agcagataaa
    21961 aaaacgatac aaaagaaaca cataccaaga gaaagcataa agacaacgac tgattttcgc
    22021 acatcatctt gatcgattct ccgtccaaaa atattgatgt tatcttcact tttgaggaag
    22081 gaatatagat acaaaccgat gattgctaca gtagttgttc gaatcccgcc gcctacagaa
    22141 ctaggactgc atccgataaa catcagtaaa gaaaaaatga tcagtgttgt gatttgaaaa
    22201 tcacccaaat cgtgaatctg cagaccagca ttacgagtcg taatcgaata aaacatcgaa
    22261 ttgatccatt tgacactcat attggaatct tggaataaat ggtccttttc caatagataa
    22321 atcaagacag ttcccgaaac aaacaagata acaaaagcta acacagctaa tttggtaaac
    22381 aaggaaaaac gaaacggaag cttcgcattg gaacgtttgt ataatagcca ttcccggcac
    22441 tccatcaata caggaaaacc aattcctccg acaaaaatca aaaacatgat caggatcaag
    22501 aaaaaatagt catgtgcaaa gggcttgatg gaatccccag tgacgtcaaa cccagagttc
    22561 gtgacagccg atatcgcctg ataaaaaccg taaaaaacgg catcacgcca acgatcaaaa
    22621 tagcctctgt aataaaaata aatagaaaag aatgtcccaa aaagtaattg aaaccagatt
    22681 aaaatagcaa aagtgatccg aatcagtcgg acgataccag acaaacgcgg ttgattcata
    22741 tccgtcatga tcagctgtcg ctgtttcagt gtgatccgtc gtttagaaaa aatgacaaaa
    22801 gcagtagaaa tcatcatgat ccccaaacca ccaacttgaa ataatatttc cagcagtata
    22861 ataccgttat cattgaacac agaattgata tcaaaagtcg atagtccagt cacactcact
    22921 gtactgattg ccatgaacag catgtccaca aaagaaacat ggctatctgg ttcgcgaaaa
    22981 atcggcatat aaaatagaac gagtgataag accgtcatca atatataata aaaaacgatg
    23041 atttggatcg atgagaaatg attggcagca aacttctgtc ctcgccgctg cagccttcga
    23101 aagaataaat caacatgcac agtactatcc tcctgacaat agtcgtttct accagtatac
    23161 aaggggaatt aggaatactc aaagaaatta tcaaacagat aacaatacag ctttcgatta
    23221 aaatagaaat ggcttataat aaggaaaatc ctagaaaaaa gaaggaggag gaataacaaa
    23281 ttgattaatg ctcaacaaat cgtagaaaaa atgaaaaatc aaaaaataaa ttatgataca
    23341 gttctgaaaa aaatgatcat gcaatgggag aaagaagaag taaagcctaa gatattaata
    23401 catacatgct gtgctccttg cagtacgcac acattggaat tcatgtctca atatgcagag
    23461 atcacgttat ttttttcaaa ttcgaatatt catcctaaaa gtgagtattt gcgaagatta
    23521 catgaacaaa aacgatttgt agaccaattt aatgagaaaa ctgaccatca tgttgcgcta
    23581 atcgttgatg aataccgtcc aaatgaattc accaaaatgg ttttaacaaa ccatcttgaa
    23641 aacgaaaaag aaggtggtgc tcgctgcagt gcatgcttca atatgcgatt agatcttgtt
    23701 gcgcaaaaag cgcaagaact aggatacgat tactttggaa gtgccctgac catctcgcca
    23761 aagaaaaatg cagctttgat caatcagatc ggaatggata tccaaaagat ttacgggaca
    23821 caatacttgc caagtgattt caagaaaaac aaaggctatg aacgctcttt gcaaatgtgc
    23881 aaagagtatg atatttatcg ccaatgttat tgtggttgcg tgttcgctgc caagcagcaa
    23941 ggatgcgatc tgaaagaaat caatcgggaa gcaaaagctt acttaaaaac atcaaccgta
    24001 gtttttgagg aaaattaaag aaatctttcg gaaaaacgta agaaaaaaat aaagaattta
    24061 tggtagaaat aaggtagact gtataatttg tccgtagtaa agtaaggaaa caagaataaa
    24121 tttcaatgaa ggaagagata agatgcgaaa agtagcacct attttgaagc caatcgctgt
    24181 attaacaatc tcgacgattg tcgcgactac tacaggtatt gtgaatagtt ccagctaccg
    24241 tgcaccaagt tcaagttcta gtactgtaga agaaacaaca ccaactactt cagtctcgac
    24301 atctgaacca acaacaacgg aaagtttgaa tgaaaccact acgacaagta catgggacga
    24361 tacaacaact agttcgtcgt atgatgagac atatacaact gacagctcaa gcgaaacaag
    24421 taatacggta ccagatggca ctccatcgga ttcaaccaat ccaagtacaa gtccggatac
    24481 aagtgctagc tccgaaacga taccaagcag tacgactgta gatgataaca cgcaaaatga
    24541 tgatgcagca cgtacagcac agcaaaacca agattcagga aatacccaaa cgtataacca
    24601 gcaagcaggt gattctcaat gacattttta ctagacctta tcaacggggt gcataaattc
    24661 cttggctatt tagacatcag tcctaaatat cttaaccgtg gatatacgat tttaagtgtg
    24721 attcccacgc tttatttatt gagaattgtt tatggacttt ggcaaaacca aaactatctt
    24781 caatttttct tatatggact tgcatttcta gtgcttgttt attttactgt tttaaatgta
    24841 ttttattact ttttagataa aaacacgaaa gccgatgtca ctcagctttt tgtgaagtat
    24901 ttacctgatg aagcgttcaa catccagaca gaagaatcga tagataatgg aaattcgatc
    24961 gataaagtga atacacaaga ggtcatggtt tcttatgacg aagattatca attgaaatta
    25021 gccgagaata tgcggtattt gattggaaat ggtgagatca aaacaaatga actcggtcgc
    25081 atggatggat ttctggtcga tagaaataca ttgtatcctt attactatgt caagaaaaca
    25141 ggagagaaag agtatgttct aaatattgga cgaagctact cggacatgga aaaagtaggg
    25201 accattcgac ttgactcaac agaagacaca ttggaacctg tcggattgtt catcgtcggc
    25261 ggtgattttg tcaaagacgg gttacgctat catgagcctt atcgtctgaa attgattgca
    25321 aaaaaggcac agtcgcagga agaaccagtg gtttatagtc gtagccaaag aagaagacat
    25381 tcataatgtg atgaaacgcc gtgtatcagt ggttgcgata aaaacgttta ttcggaataa
    25441 gggggatgtg acacgtcttt tgtcacgttc cttttttata taacgagaaa gataagacga
    25501 acacatcact tattctttcc tttcatttat aaacattgta gaataaagaa agtacaacga
    25561 agtattgtga aaaaacgtaa taaataacga ggaaaataca agtaggaggt aagctgtgaa
    25621 agaatttttg aaaaattggg ggattttgat ccttgtatta gcggctattt tattagctag
    25681 agtgtacgtg tttacaccag ttactgtaaa cgggcattcg atggacccta cattaagtga
    25741 tggacaacga ttgatttcat ctaagatctc aaactatgaa cgaatggata ttattactac
    25801 aaaggaaccg ggggatgaag aacggatgat tgttaaacgg atcatcggta tgcctggaga
    25861 tacagtcaag atggaaaatg accagttgac cattaatggc aaaaagtatg atgaacctta
    25921 tctggatgag ttcaaaaaag aattttcaga agataagtta caaggagaat atgcttatag
    25981 ctcaggattc caagcacaag cagaaagttc atccaccttt acgagtgact ttgaatatac
    26041 tgtgccaaaa ggaaagtatc ttgttctagg cgataaccgc ttgatttcaa aagacagccg
    26101 aatgtttggg ttagtcgaca aagatatgat ccaaggaaaa gttgttttcc gttattggcc
    26161 tctttcagaa attaaaatca tgtgatgaaa aaataaaaag aagctgtgac atgttttttg
    26221 tcacagcttc tttttccgaa aattccttct tatttcttgg agttgctcac tttttttgca
    26281 atctcatttt aagctttttg gctgatggat aagaaaagcg aagcgttttt gttcataaat
    26341 agcttttccc cacgatggaa ggtatgacta gtagcagaga caaagcccgt tttttccaat
    26401 cgattattca attcttcttg gctaaagcca ttatggactt tcggatgact aatttgttca
    26461 ttcttgtcaa agtctacgat gatcaattga ccgccaggag ctaaaatttc ataaagtttt
    26521 gtaagaatat tctccgtatc aggaatgtgt aaaagtacaa gtgatagaag gatgagatta
    26581 gcttggacag caggaaattc gacagaagca tcagcgtgga tcgttcggac atttttcaga
    26641 tctgctgctt ggatcttttc ttctgccatt ttcagcatag tttctgaagc atcggcaatg
    26701 atcagttctt tgaatctttc cgcaagcggt aaactaacaa gcccagttcc gcctccgtaa
    26761 tccagcagga ctttttggtg gctgtcgcgc ggtagataag tagttagttc ttcgcgaata
    26821 atcttggcta atgcttgacg gtcaggggaa tcataatggt tagcgatgga atcaaaaata
    26881 ttttttgtca tcaaatagct ccttacgtaa aactttgaaa ttttaactta ttatagcacg
    26941 tgaaaagaaa gaaagcatgc tatactcaat tcaaaaaggg agaatctaga aagaatatgc
    27001 cgatatcgtt tgtaaaagat agagaggaaa aaggaaagtg tgtccgagaa atattactag
    27061 acttgcctga gtggtttggg cttcctgaat caacggaaaa atatatcgag gaatcaagta
    27121 aactaccttt atggtgtgaa aaaagaaaag aagaatattt aggctttatc actctttcac
    27181 agacaagtga agatactgcc gaaatctatt ctattgtatg ggaataaaaa aagactatca
    27241 tcaccaagga ttaggaacaa aactttttaa agaagcagaa ggttacgcag caaaacatta
    27301 caaatatttg caagtgaaga ctgtagacga ggggcactac tctatatatg atcaaactat
    27361 ttgtttctac gaatcattag gattttcaag gttggaagtt tttccaaatt tatgggatga
    27421 atggaaccca tgtttagttc ttgtcaaaaa attggaacaa aagtgagcaa tagatttaat
    27481 actaatctgt gcttgatgaa aattctcact gtaaaaaatg ctgaaaatca agtataatac
    27541 cataggaaca aactggaagg tgaaaaagag catggcacaa ctatttttta agtatggcgc
    27601 aatgaatagc ggcaagacga tcgagatcct aaaagtcgca cataattatg aagaacaaaa
    27661 taagccagtt gtcttaatga caagcggtat tgatacaaga gatggtttag gcgttgtttc
    27721 aagccgaatc ggactgaaac gtaatgcgat gccgatattt gaagaaacag acgtatttga
    27781 cgtaattcag aaaatggaaa gcaaacccta ttgtgtgctg atcgatgaag cgcaattctt
    27841 aaaaaagaaa catgtcattg cttttacgag aattgtggac gaattggata ttccggttat
    27901 ggcatttggt ttgaaaaatg attttcgaaa cgagttattt gaaggatcaa aatatttatt
    27961 gctttatgca gacaaaatcg aagaaatgaa aacaatctgt tggttctgcc acaaaaaagc
    28021 aatcatgaat ttacattata ttgatggaaa ccctgtttat gaaggcgatc aagtgcaaat
    28081 tggcggaaat gaagcttatt accccgtttg tcgaaaacat tactttcacc catcaatgat
    28141 tacagaagga gaataagcat gtacgatcaa ttacaagcaa ttgaagaccg ttatgaagag
    28201 cttggagaac ttttaagtga cccagaagtg atttctgata caaagcgttt tatgcagctt
    28261 tcaaaagaag aagcaaacac gcgcgaaaca gtcgaagttt atcgtcgtta taaagaagta
    28321 gtacaaggaa tcaccgatac agaagaactg cttggtgaaa aactggatga tgaaatggct
    28381 gaactagcaa aagaagaatt atctgaatta aaaaaagaaa aagaagtctt agaagaaaaa
    28441 atcaagatct tgcttttacc aaaagatcca aatgacgata aaaatatcat catggaaatc
    28501 cgtggagcag caggcggaga cgaagcagca ttattcgctg gcgatctttt caatatgtac
    28561 caaaagtatg ctgaagcaca aggctggaaa acagaagtga tggaagctaa cgttaccgga
    28621 atcggtggat ataaagaagt gatcatgatg atcaccggag acaacgtata ttcgaaatta
    28681 aaatatgaaa gtggtgcgca ccgcgtccag cgtgttcctt caactgaatc gcaagggcgt
    28741 atccatactt ccaccgcaac agttgtcgtg atgccagaag ctgaagaagt agagatcgat
    28801 attgaagaca aagatatccg tacagatatc tatcatgctt caggtgctgg cggacagcac
    28861 gtcaataaaa cagcatctgc tgtacgtttg actcacttac caacagggat cgttgttgct
    28921 atgcaagatg aacgttctca aatcaagaac cgtgaaaaag caatgaaaat cttgcgtgct
    28981 cgtgtgtacg ataagatcca gcaagaagca caaagcgagt atgatgccaa tcgaaaatca
    29041 gcagtcggaa ctggggatcg ttcagaacgg atccggacgt ataatttccc gcaaaatcgt
    29101 gtgactgatc atcgtatcgg attaactatc caaaaattag atcagatttt agcagggaaa
    29161 ttagatgaga tcgttgatgc attgatcatg tatgatcaaa catcaaaact ggaagctatg
    29221 caaaatgggt aaaatgacct atcgagaagt cctgtcacgg gcttcttctt ttttagagga
    29281 tcatgggaaa gaagcatata gtatccaatt tttatttttg gaacgaaaac aatggaaaaa
    29341 acttgattgg ctccttcata tgaacgaaga gatttcagaa gaagaacagc ggttgatcga
    29401 aaccgatctg cgacttctgc ttgcagatca tccacctcag tatttgctag gatatgcaga
    29461 tttttatgat catcggttaa aggtaactga agcaacactg atccctcgac cagaaacaga
    29521 ggagttagtc gaatggtgtt tagacgagac gcctggtgta ccgttagaag tgatagatat
    29581 tgggacaggg actggagcaa ttgctattag tttgaaagca gcaagaaaaa attggcatat
    29641 atctgctgtg gatctttcag aagaagcatt agaagtagcg aaagaaaatg ctcagaaaga
    29701 aggaacgaaa atcagttttt atcatggaga tacattagga ccagtaatgg atcagcaatt
    29761 tgatgtgatt atttctaatc cgccgtacat cagtcggaat gaatgggaac tgatggatga
    29821 aagtgtccgg tcattcgaac ctaaaatggc cctttttgct gagaacgatg gattagctat
    29881 ttatgaaaaa atagcagttg aagcaccaag cgtactaaaa tcaaatggaa agattttttt
    29941 agaaatcgga tttcgccaag gtgaagcagt aaaaaaaata tttcagcaag catttccaga
    30001 taaaaaagtg gcgataaaaa aggatctttt tggcaatgaa cgaatgatcc aagtttatgg
    30061 ttgaagttgt ggatgaaaaa ttttttattt gtttttttat tataaaaaaa cacttatttg
    30121 acaaggatgt aaacgacttt ttggtttatc aacaagttta tccactattg acaaatagat
    30181 tatccacaaa cagtggaaaa cttgaggata aactcagaca aaataagaat gtatgaaaaa
    30241 ggggttgtgg ataaactgtg gaaacgaaac gatatgatga aacagaattg caagaggcag
    30301 ccgaagcact gaaagaagga gaacttgttg cttttcctac cgaaacagta tacggattgg
    30361 gcgccaacgc tcttttacca aacgctgtca agaaagtgtt ttctgtaaaa gggagaccgc
    30421 aagataatcc attaatcgtc catgtcgcct cttttgaaca agtaaaagag tatgtggaca
    30481 actttcatcc ggcagcagag aagattgtga agaacttctg gcctggacca ttaactttga
    30541 tatttaagat caaaaaagac actttgccct cagttgtgac gggaggatta tccacagctg
    30601 catttcgtat accggataac aaaaaaacac tagaagtaat cgaactttcc ggtgttccgc
    30661 ttgtcggtcc aagtgcaaat acgtcgggaa aaccaagtcc aacgactgca gatcatgtat
    30721 atcatgatct acaaggaaaa attaccggga ttattgatga tggagctacg cgaattggtg
    30781 tagaatccac tgttcttgat ttaagtgatc caacagccat gcctatgatt ttacgaccag
    30841 gtgcagtaac gaaagaacaa atcgaagcag tcatcgaatc tcctgttgct attgatcagc
    30901 atcttgtaaa agaaaatgaa acaccaaaag cccctgggat gaaatacaaa cactactcac
    30961 ccgatacacg tgttctgatg gtcagagatg gcgattggtc aactgcagtt caatgggcaa
    31021 aaaataagaa gatccgtgca ggtgtcatag caagccccga aattgcggat caagtgcgga
    31081 cagatactgc agctgtttat atgtataacg acaactcagt agaagcggcg gctaaaggat
    31141 tgtttgcagg tctaagagga ttagatgaac caacacttgg attagatttg atttttgtac
    31201 aagtgtatcc agaaactgga ttggggaatg cttacatgaa tcgcttgaaa aaagcagcag
    31261 gacaaaatta ttttgaaaaa tgatcaattg gttattgtcg cattctttta gtatgataca
    31321 atgctatcaa gtaaatcttc tatcagtgaa cgaaaaacta agcgtaacta atcgtaatag
    31381 aagagatacg aatatttggc aatttgtttt tgatgggaaa aataaaattg taggaaaata
    31441 aaaaggagct gttgtttgtg gtagattaca aaacgtttga ccctgatctt tgggctgcga
    31501 tcgccaaaga agaagaaaga caagaacata atttggagct gattgcctct gaaaactttg
    31561 tctccgaagc agtgatggct gcacaaggaa gtatcttgac aaataaatac gcagaaggtt
    31621 atccagggca tcgctattat ggtgggtgtg aatttgtcga tatcgttgaa aatttagcga
    31681 ttgaccgtgc aaaagaatta ttcggagcga aatttgcgaa cgtccagcct cactccggct
    31741 ctcaagccaa cacggctgct tatctcgctt tggtagaacc aggggacacg atcttaggaa
    31801 tggatctttc cgcaggcgga catctaacac atggatcacc agtcaacttc agtggcaaaa
    31861 cctatcactt tgttgcttac ggtgttgatc cgacaacaga agttattgat tataatgtgg
    31921 tacgtatttt agctagaaaa catcaaccaa aattgatcgt agcaggtgcc agtgcttacg
    31981 gacgaacgat cgactttgcg aaattcagag aaatcgcaga tgaagtaggc gcaaaactga
    32041 tggtagatat ggcacatatc gcaggattag tagcagcagg acttcatcct aatccagttc
    32101 cttatgcaga tatcacaacg actaccactc ataaaacatt gcgtggccct cgaggcggca
    32161 tgattttgac aaacgatgaa gcattagcaa aaaaaataaa tagtgcggta tttcctggta
    32221 ttcaaggcgg ccctctagag catgtgattg cgggtaaagc agtagcattc aaagaagcat
    32281 tagatcctgc atttaaagaa tatagtgaac aaatcatcgc caatgcaaaa gcaatggtca
    32341 aagttttcaa tcaagcaatt ggaaccagag tcatttcagg ggcgacagat aatcatctga
    32401 tgttgatcga tgttcgcgag ttaggtataa atggaaaaga agcagagagc attttggaca
    32461 gtgtgaatat cactgtaaat aaaaactcga ttccttttga aacactaagt ccattcaaaa
    32521 caagcggtat tcgaatcggc acgccagcaa tcactactcg cgggttcaaa gaagaagatg
    32581 ctgtaaaagt ggctgaacta gttgtcaaag cattacaagc aaaagatgat aacgctcaac
    32641 tagacgaagt caaaacaggt gtacgcgaat taactgaaaa atttccgttg cataaaaaat
    32701 aaaaatttaa attccattag taaacagaaa agttcaatgt tgggcttttc tgtttatttt
    32761 ttgggaaaac ggattctttg acaatatcgg tgatgctctc tagtatatga ggtgtaattt
    32821 tagtcttcac actaaatctc agggaggaaa agtcatgact gatcgtatct cgttagaaaa
    32881 ggaagcagta gcattcagtg atgcaaatgc gcctcatccg cgtatctatg aactagcacc
    32941 ggaagaagga agagttttac tagaagaagt acaagaatca cctgtgaaca aatattccgt
    33001 cgatattgaa gacttgatgg tggatactgg cgaatgggga aaactcaata ttcgtctcgt
    33061 acgaccagaa gggaatatgg ataaattacc agttattttt tatattcatg gagcaggctg
    33121 ggtttttggc agtgctcaaa cccatgataa attgatcaga gaacttgcgg ttcgtacgaa
    33181 ttccgtcgtt gtctttccag aatatagtcg atcaccagaa gcaaaatatc caacagcaat
    33241 tgaacaaaat tatgctgtgt tgcaacagct gaataaatta gccaagtcaa aaaatctgga
    33301 tctcgagaat ctaatcgttg caggagattc agtaggtggt aacatggcta cagtcatgac
    33361 gatcttaaca aaagaacgaa agggcctccc aatatccaag caattgctgt attatccagt
    33421 cacaaacgct gattttgata cagattccta tcatgaattc ggagaaaact attttttgac
    33481 aagagaagga atgatgtggt tttgggacca atatacgacg aatgaagaag agcgtgctga
    33541 aatcacagct tcgcctttga gagcaaatat aaatgaacta aatgatcttc cttcagcaat
    33601 gattttaacg ggagaagcgg atgtattaag agatgaaggt gaggcttatg cgcgcaaact
    33661 tcgtgatgca ggggttcctg ttacacaagt acgcttccaa ggaatcatcc atgattttgt
    33721 catggtaaat gctatggatc agacaaaggc aacgcgtgca gcaatggcat tatctacttc
    33781 ttggatcaag aaaaaagaat aagctttgct tgtccgcagg aaaacttctt ttcaaaaacg
    33841 gattttctta ggaaaaatgg cgagtttgac tagtcaatca cttgattttg ttttacaatt
    33901 aaaaagaaac gacagaacaa aggagagctt aaaaaatggg caaatttcaa gtgatcgatc
    33961 atccattgat tcaacacaaa ctaactatta ttcgggacaa aaactgcgga acaaaggttt
    34021 ttcgtgaagt agtcgatgaa atcgctatgt tgatggcata tgaagtatca cgggatatgc
    34081 cattggaaga catcgtgatc gaaacaccga tcactgaaac aacacaaaaa acgttgtctg
    34141 gtaaaaaagt agcgattatt ccaatcttgc gcgcaggtat tggaatggtt gacggtatct
    34201 tggaattgat tccagctgct aaagtgggac atatcggtct ttatcgagat gaagaaacat
    34261 tggaaccaca tgaatatttc gtcaaacttc cagaagacat tgatgcacgt cagttgtttg
    34321 tagtagatcc aatgttggca acaggcggat cagcaatcat ggcaatcgat gcattgaaag
    34381 aacgtggcgc gtcgaacatt aaatttgttt gtttggtagc agcacctgag ggagtaaaag
    34441 ctttgcaaga agcgcatcct gatattgaca tctatacagc ttctctagat gaaaaattga
    34501 atgaacatgg ttatatcgtt cctggactag gggatgcggg tgaccgtttg tttggtacaa
    34561 aataagtaaa tacgaaaaag ggtgtgacac aacttttgtc acatcctttt ttggtcattt
    34621 ttaacgtttg atgcagaaca gctttttcac agctttcgtt tgcatataaa aaaaccatcc
    34681 caaaaatgca gagatggtca aattcaaatc ttttttagtt ctttgtagtt aacgattact
    34741 acacccttac tttgcgtcat caagttcgca ttttctgcag tttcatcaat ctcaacaaca
    34801 gcggaatttt tcaattgctt tgaaatcgtt ccagtttgcg acttgccgtg aattgtgaac
    34861 attacgtgag tattgatctt gaatttttca ccaatttccg atggtacgat agttgtatca
    34921 aattttccaa aagttgccat tttcataaaa cctgcctttc acatcaatta taccacgttt
    34981 tatgaaaaat atcatgaaat taaactaatt ttccatcgga ctctttacaa tcagccaaat
    35041 agagtatata atttcttttg gataaggcca gcttagctca gttggtagag caacgcactc
    35101 gtaacgcgta ggtcgtaggt tcgatcccta tagctggcat taaaagagaa gacagatata
    35161 tcaaggattt ttaatccatt gatacatctg tctttttgtt taaaggaaat aaagtatgct
    35221 ttcttagcaa tagagcatgt attatttcta taaaaattta ggagaataaa acgactagca
    35281 atatagctgt gaaatcaaat atcacatgaa ctgcccaact tgtaatgatc gagttgcttt
    35341 taatggcagc ttggttgaat aacaatcttg ccaccccttg tatcaaaagg atgtgtgcta
    35401 cagtgtgtaa aatatttcca ttatcataag tactgtaatg gataaatcca aagatgattg
    35461 ctgacaagaa actagcgaca ggaatgctga acttactaga aaaaatagcg agaaaataca
    35521 ctgagaacaa ttcttctcca agtatcatga taggcaaaat aataaataat aacgggctga
    35581 aagcctcatt tattggattg cctgttaaac cccatttcaa aatttgttgc aaaaataccg
    35641 agactgcggc actgattact acattgataa aaaaatattt ggctatattt ttgacaggag
    35701 cgacaggttt cgagaacatt tttttcgtat cttttttacc aaaaacaagt gtaaatgcta
    35761 taaatccagt gatagttaaa gaaaaaatgc taataatgga tggcgcaaat agcaacccta
    35821 acaaaccgag tacaacgaca atagtgccca atatcccttt tttaagttct attttttttc
    35881 ctaaaatgtt attcatgata ataactccta ctattcagtt tttgaagata gagtcagtat
    35941 acatgaagag ttaaaatagg caatgttttt ttatggatat ttgtattgct aaaaatttat
    36001 cttatatatt cattttgatt atactacttt tatttgtaaa aattttctag caaaaccaag
    36061 tgcttgcaac tgattaagcg tacaattttt tagatgttcc gagcgtactt caatcatttc
    36121 aaaggagttg ctacttaaat cgatattttt taaatcagta tcaaaaaagc tagcattttc
    36181 taaatcatta gtagaaaaca ttattttagt gagggaacag tctacaaaat ctgcgcttga
    36241 taagacagag tgctcaaagg tactttcttt tatgtttgaa ccagataaat ttacatagtc
    36301 cattttacaa ttctcgaata acgtgttccc aatataactt tccatcaatt tagtacctgt
    36361 taatttacaa ttgacaaatt tcacgcgatg caacatgctt tttgtcaata tacagcctga
    36421 aaaatcacag ttttcgaata tacagtcggt aatctccatt ctttgaaaat cattggaagc
    36481 aaaaaatgca tacttgaaaa tagatttgta aataattgga tggcagatta tttggttttc
    36541 gatgacctct ttttgtgaaa ggatattata cagttcaaaa tcttcgtttt catagatatg
    36601 aaaaaaggat cctttattca agcttgcttc attaacttta ggaaaaatca tatttaatta
    36661 cctccatttt cataaagtca tattaacaaa agctaaacca acttacatta gcagaaaatg
    36721 agataggttt tcgccttttt cgataacgat agtgtcgcta tctcttgaaa cgttcttaga
    36781 attgccctga gagacacaaa ttaggcgtaa ttctaataaa aatcttagaa taaaaatttt
    36841 tactgattta atttagaatg tttttaaaat aaaaatcgtt gccataacag tgtattgaaa
    36901 ggttttaaca atccagtaat gatttaaaaa aatctagatg tagcgtatac tttgtttata
    36961 gaatgtagtg ggaagaaata tatttttggg aggaaatcgt gatgtctaaa agtgaagaaa
    37021 tagaaaacat ggtactaaaa ttatatgatc tcgttttaaa tccagagatc aaagaaaagg
    37081 aacgtatact tttgatagac gcaaagacag gcttagaaaa aggtcagtat tatcctaaag
    37141 tcataaataa tttggaacgt agtttacgtc cgttagcaat caggggagaa ttgtctaaac
    37201 cagtatcacc gttttatatg gagatatcaa caataggaaa atttgaaaaa gaattaggtc
    37261 gaggaatggc ttcggcaccg attacttttg ggcatttata aaaacgagtt attcatctca
    37321 atgaattaaa aagtatagtc aatctcataa tgcaggctag gttcatttat ttgaacagag
    37381 tctgtatttt tttattctaa ataaagaaac agatgtttct ttatattgta ttttatcctt
    37441 taattaacac aaaaacagct agtataaact aataatgtta attaaaagtg tattttatga
    37501 aactatcgtt atttattaat gttgcatttt tgtaagttaa aaattggaaa tatagattga
    37561 aaaaatgaaa gcaataagta aaataaaatg aatatatgcg aaaaaataat ttacattagg
    37621 aaaaaccttg taaaaacagt tttttggcat atttattttt tataaatatt tgtaaaataa
    37681 ctatcaattt tttagttaaa agattggaaa tgagtggggg aggaattgaa gaaaggattt
    37741 ttgagagatg atatagtagg ttttattttt agttaaaata ggggagatag aaaaaatgaa
    37801 aaagtgtaga aatattattt tatcaatgtt atttattatt actaatataa catcactgat
    37861 tcctgttcat gtctatgcgg atgcaggcag agatatcagc agtaatgtca cttcgttgac
    37921 cgtggaccca acgaatatta cagatggagg aaacataaaa gtaaaattct cgtttgacga
    37981 aaaaaaacaa aatatccaac caggtgatta tctttggatc aattggccaa gtgaaggaaa
    38041 tattcgcggt gaaggattcc aaaaagaaat cccattaatg attgaaaata aaaatgttgg
    38101 aactttaacg gtcagaaaag attctgcgca ggttgtgttt aatgaaaata ttaaaaacct
    38161 agactcagta gaaggttggg ggcaatttga gatacaggcc agaaacgtaa ccgataccgg
    38221 tgaagaaaat acgggaccat tcaccgtgac gagcggtgat aaaacagcta ctgtaaatgt
    38281 gacaaagcca gcttctggtt cttcttctag cgttttttat tataaaacag gagacatgct
    38341 acctgaagat actaagcaca ttcgatggtt tttgaatatt aacaataacg gcacttatgt
    38401 tgaacaacca gttaaaatca gtgatgaaat ccaaagtgga caaagattag atccaagtac
    38461 gtttgaaatt aatcaaatac acttaggtga acagaaggtt tatagaggag aagagggaat
    38521 ccaacaattt ttacaagatt tccccagcgc tacatttaat ttttcagtaa ctgataatta
    38581 cattgaaata actataccaa aaaactttgt caatcttagg aaaataatgg tgagttataa
    38641 gacgatcata gaaaacccag aacaaataaa ttttgagaat cattcggaag cttggtttaa
    38701 agaatttaat aaacctgctg ttgatggaga aagtttcaat catacagtta aaaatatttc
    38761 agcttctggt ggagtcaacg gtacagttag aggcgaattg aagattttca aatatatcaa
    38821 tgacacagag attggtatcc caaatgtgac tttcgaatta agacgagcag atgaacagcc
    38881 tattcaagga cagtctagta tcctgttgac ttcgaatgaa cagggagaag ctagtatcaa
    38941 aggcctgcaa gtaggagact atgttgtaaa agaaaaagaa gcacccaatt ggattgattt
    39001 tgatccacta agttcaaatg aactcaaatt ctccataaac gaaaatgata cagagggagt
    39061 cagtttacct atttataaca agaaaaaggt tacgaacatc acagcaacta aaatttggaa
    39121 cggtggaacc actccaagac cgagtattta ttttaaatta ttcagagcaa gtacaaacaa
    39181 ttgggaacca gttcctgatg cagaaacaaa acgattagac aatggaataa cttcagtgac
    39241 ttgggaagat atccaacagt atgatgatag tggaaacgaa tatacgttta aagtgcaaga
    39301 agtagatcaa aacggaaatg attatgtccc ttcaggttat caaaaaattg aaaacgggct
    39361 agtcgttaca aatgagaata aagaagtcat ttcagtctca ggacaaaaaa catgggaaga
    39421 caatgagaac caagacggca aacgaccgac gacgatcaca gtaaatctat tagccgacgg
    39481 tcaaccgatc caacacaaag aagtaagtga aaaagatgat tggcgctatc gtttcacaaa
    39541 tctgccaaaa tacagagacg ggcaagaaat catctatact gtaacggaag acaacgtgcc
    39601 cgaatacagt acgacgattg acgggtataa catcaaaaac agttatacac cggaaaaaac
    39661 aaatatatct ataccaggta gccatataac accgtggaaa aattttccag agaagacaga
    39721 gagagagaaa attagaaatc tattctctca aaaattgcaa atatttgctc atacaggaga
    39781 atccagcgaa caaagaagca attatattag taagagagct gtacctaaac agataacaaa
    39841 taaatcaaaa agcattcttc ctaaaacaag tagtaaaaaa tctagttttg ctgtaatcat
    39901 tggtttattg atagtaacta tctgtgctgg gatattctta caaaaatata aaaaagttta
    39961 gttagaatat aatatttttt gttaaatatg actgaaatca aaagaataaa attccgattt
    40021 ataatcgaaa aaagaagcat ttttatatat gcttcttttt tcgtagaatc aataaatatg
    40081 gatttggcta actatggaag aatactcgta ttagttttca gcgttcatac tagttgttac
    40141 attgtttgat tggccaaaag aatttctgat atattttgtg ctaaataaag aaaaagacgc
    40201 ttgaattggg aaataagaaa actactctat cattacaaat tttcataaac tggcagatgt
    40261 tctaagtaaa caagtatctt ttcaaagtcg gaaaaatcca taatcaacgt agtggtattg
    40321 atatttggat gaaagcctac ggtatcttga cgatcaatag cagcatcgat cacgacttgg
    40381 atttttttct ctttgtcgtg catcaatgct aatggagtca ctgtacctgc tggaacgcct
    40441 aggaggtcag gaagctgttc ttcagaaaca aaagataagc gcttttcttt taattgttca
    40501 gctagttgtt ttaaatcggc gtgcttttca tcaggcaaga tgacaagata gatttgtttt
    40561 ccttttcttg atttcaataa tagatttttt acttgcggac caggtaggga aaaagggaca
    40621 tttttgactg acgtaatcgc aggatgatcg actttttgaa aagagatacc cagttttttt
    40681 agtagttcat aagcttcttg ttcggttgca cgactcatcg cgcatcaccc tccttttttt
    40741 attagtgtat cataaaaaag agttgacaaa tgaaaaataa tcatgtaaat tacacgtaaa
    40801 gttaaaacaa atgacatcga aaagaagagt agccgttagg tgtttttaga gagtctctgg
    40861 ttggtggaaa gaggcagcag ttaaccgtga aacacatctt ggagtcgatt ttctgaagcg
    40921 tatagtagga aaatccgggg agcccgttac agctgcggtc gttgctagat gaccagataa
    40981 ggctggcttt tccgtgagga gtcggtaaaa aaaggtggaa ccacgtgatt aacgtccttt
    41041 gatcttcgga tcaaaggact ttttgttttc atctgaacgg caacgactgt gtgaggtttt
    41101 ttctgcaagg aaaaaa
//
LOCUS       DAFBSV010000014        40376 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.014, whole genome shotgun sequence.
ACCESSION   DAFBSV010000014 DAFBSV010000000
VERSION     DAFBSV010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.014"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(161..2158)
                     /gene="tkt"
                     /locus_tag="LLB18_000748"
     CDS             complement(161..2158)
                     /gene="tkt"
                     /locus_tag="LLB18_000748"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBK5243769.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2260..2511)
                     /locus_tag="LLB18_000749"
     CDS             complement(2260..2511)
                     /locus_tag="LLB18_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HBK5243770.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2658..3281
                     /gene="lexA"
                     /locus_tag="LLB18_000750"
     CDS             2658..3281
                     /gene="lexA"
                     /locus_tag="LLB18_000750"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBK5243771.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3461..3679
                     /locus_tag="LLB18_000751"
     CDS             3461..3679
                     /locus_tag="LLB18_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243772.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3968..4480)
                     /locus_tag="LLB18_000752"
     CDS             complement(3968..4480)
                     /locus_tag="LLB18_000752"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBK5243773.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="LLB18_000753"
     CDS             complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="LLB18_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBK5243774.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6933..7376)
                     /locus_tag="LLB18_000754"
     CDS             complement(6933..7376)
                     /locus_tag="LLB18_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HBK5243775.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7377..8165)
                     /locus_tag="LLB18_000755"
     CDS             complement(7377..8165)
                     /locus_tag="LLB18_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBK5243776.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8162..9103)
                     /locus_tag="LLB18_000756"
     CDS             complement(8162..9103)
                     /locus_tag="LLB18_000756"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBK5243777.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9280..9867)
                     /locus_tag="LLB18_000757"
     CDS             complement(9280..9867)
                     /locus_tag="LLB18_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HBK5243778.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10088..11395)
                     /gene="obgE"
                     /locus_tag="LLB18_000758"
     CDS             complement(10088..11395)
                     /gene="obgE"
                     /locus_tag="LLB18_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBK5243779.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11689..12699
                     /gene="gap"
                     /locus_tag="LLB18_000759"
     CDS             11689..12699
                     /gene="gap"
                     /locus_tag="LLB18_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBK5243780.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12784..13719)
                     /locus_tag="LLB18_000760"
     CDS             complement(12784..13719)
                     /locus_tag="LLB18_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK5243781.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            13905..14864
                     /locus_tag="LLB18_000761"
     CDS             13905..14864
                     /locus_tag="LLB18_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HBK5243782.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(14950..16044)
                     /locus_tag="LLB18_000762"
     CDS             complement(14950..16044)
                     /locus_tag="LLB18_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBK5243783.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            16233..16994
                     /locus_tag="LLB18_000763"
     CDS             16233..16994
                     /locus_tag="LLB18_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBK5243784.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            complement(17109..17549)
                     /gene="fabZ"
                     /locus_tag="LLB18_000764"
     CDS             complement(17109..17549)
                     /gene="fabZ"
                     /locus_tag="LLB18_000764"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBK5243785.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            17769..18524
                     /gene="fabI"
                     /locus_tag="LLB18_000765"
     CDS             17769..18524
                     /gene="fabI"
                     /locus_tag="LLB18_000765"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HBK5243786.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            complement(18634..19647)
                     /locus_tag="LLB18_000766"
     CDS             complement(18634..19647)
                     /locus_tag="LLB18_000766"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HBK5243787.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            19812..20732
                     /locus_tag="LLB18_000767"
     CDS             19812..20732
                     /locus_tag="LLB18_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HBK5243788.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            complement(21012..21512)
                     /locus_tag="LLB18_000768"
     CDS             complement(21012..21512)
                     /locus_tag="LLB18_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBK5243789.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(21619..22137)
                     /locus_tag="LLB18_000769"
     CDS             complement(21619..22137)
                     /locus_tag="LLB18_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBK5243790.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            complement(22138..23493)
                     /gene="rph"
                     /locus_tag="LLB18_000770"
     CDS             complement(22138..23493)
                     /gene="rph"
                     /locus_tag="LLB18_000770"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBK5243791.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            complement(23496..24317)
                     /gene="racE"
                     /locus_tag="LLB18_000771"
     CDS             complement(23496..24317)
                     /gene="racE"
                     /locus_tag="LLB18_000771"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBK5243792.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            complement(24479..25135)
                     /locus_tag="LLB18_000772"
     CDS             complement(24479..25135)
                     /locus_tag="LLB18_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBK5243793.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            complement(25151..25798)
                     /locus_tag="LLB18_000773"
     CDS             complement(25151..25798)
                     /locus_tag="LLB18_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBK5243794.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            complement(25811..26626)
                     /locus_tag="LLB18_000774"
     CDS             complement(25811..26626)
                     /locus_tag="LLB18_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBK5243795.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            complement(26640..27377)
                     /locus_tag="LLB18_000775"
     CDS             complement(26640..27377)
                     /locus_tag="LLB18_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBK5243796.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            27631..28641
                     /gene="trpS"
                     /locus_tag="LLB18_000776"
     CDS             27631..28641
                     /gene="trpS"
                     /locus_tag="LLB18_000776"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBK5243797.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            complement(28811..31231)
                     /locus_tag="LLB18_000777"
     CDS             complement(28811..31231)
                     /locus_tag="LLB18_000777"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBK5243798.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(31236..32279)
                     /gene="pheS"
                     /locus_tag="LLB18_000778"
     CDS             complement(31236..32279)
                     /gene="pheS"
                     /locus_tag="LLB18_000778"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBK5243799.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            complement(32588..32929)
                     /locus_tag="LLB18_000779"
     CDS             complement(32588..32929)
                     /locus_tag="LLB18_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5243800.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            complement(32998..36720)
                     /gene="addA"
                     /locus_tag="LLB18_000780"
     CDS             complement(32998..36720)
                     /gene="addA"
                     /locus_tag="LLB18_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBK5243801.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            complement(36717..40244)
                     /locus_tag="LLB18_000781"
     CDS             complement(36717..40244)
                     /locus_tag="LLB18_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBK5243802.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
BASE COUNT        11441 a         8670 c         7046 g        13219 t
ORIGIN      
        1 tcaagaaaca caaactaatc cgaagaattc tttgttttgt catttaaatg taacatagcc
       61 gaaaacgaaa agtaatattg atttattctt ctaacacata aagaacagct gtctccaact
      121 tgcagacagc tgttcttatc agtcaaacaa ttgcttggat ctatgatagt tgattgtacg
      181 tattcacgac attttctact gtaaatccaa attcttctaa aattttagtg ccaggggcag
      241 atgcaccgaa atgatcgatt gtaatcgttg cgccctctgt tcctacgtag cgttcccatc
      301 caaatgatgc agcagcttcg atagccacac gtttcttcac tgatttagga agtacacttt
      361 ctttatattc agaagattgt ttttcaaaga ggtcaaagct tggcatagaa acaacagaaa
      421 catctttgcc tttttcagcc aattcttttt gagctttcac agccaaatca acttcagaac
      481 ctgttgcaat caaaatacct tctggtgttt ctccttgtga tggagaaaga acatacgcgc
      541 cttttttcac catttcatct gctacttctt ttgtagaagg caatactgga aggttttgac
      601 gactcaatac aaggatagta ggcgcatctg ttgtctccat cgctactttc caagcagcac
      661 gtgtttcatt tccgtctgcc ggacgaatca cttgaacacc aggcatgcag cgaacagatg
      721 ctagttgttc aatcggttcg tgcgttggtc cgtcttctcc gacagcaacc gagtcatgtg
      781 ttaagacgta aacaacagga gtatgttgga ttgctgctaa acgaactgct ggtcttagat
      841 aatcgacaaa gacaaagaat gttccaccgt agatacgagt tccgccatga agttggatac
      901 cattcatagc cgaagccatt gcaaattcgc ggacaccgaa ccagatgttg cgtccttcat
      961 aatgttcagg agtgaaatct ttatctgcag ccaccattgt attattggaa cctgacaagt
     1021 ccgctgaacc accccagaag cttggtatag ctttcgataa ttcttggatg acttctttac
     1081 ttgaaacacg gcttgcttga ctgcttccaa cttcataagt tggcaattct gcatcccagt
     1141 tttctggtag tttgccatca aaagcatctt caaattgttg tgctaattca ggataagctt
     1201 ttttataatt ggcaaacatt tcattccatg catcttcagc tttttgtcct tcttctatca
     1261 tcgtttgatg gaagcgggca gctacttctt ctggaacagt gaaatctgga tactcccaac
     1321 cataaacttc tttagccatc ttgatgccat cttcaccaag aggagcacca tgaacagcag
     1381 atgttccttc tttaggagca ccatagccga tgactgtttt tacttcgatc aatgttggtt
     1441 tgtctgtttc agcttttgct tcttcaatcg ctttagagat tgcttctagg tcatttccgt
     1501 ctttcactaa gatatgttgc cagccatatg cttcatagcg agcaccaacg ttttctgtga
     1561 aagcttttga agttggaccg tctagtgaaa tatcgtttga atcgtataaa acgatcaatt
     1621 tccctagttt catatgacct gccatcgaac ttgcttcttg agatacccct tccatcaagt
     1681 ctccgtcacc gcatattgca tacgtatagt gatccatcac attaaagttt tctttgttat
     1741 acgttgctgc aaggtgcgct tctgccattg ccataccgac agccattgca atcccttgtc
     1801 ctaatggccc tgtagtggct tctacaccat ctgtatgatg tacttcagga tgtcctggtg
     1861 ttttagaatc ccattgacgg aattgtttca aatcatcgat tgtcacttga tagccagcta
     1921 aatgaagcaa gctatacaac attgctgacc catgtcctgc cgaaagaacg aaacggtcgc
     1981 ggtcagccca gttttttgat gtcgttggat ttactttcag gtgttttgtc cataacgcat
     2041 atgccatagg tgctgcgccc atcggcaatc caggatgtcc tgagtttgct ttttggactg
     2101 cttcaatact taatgtacga attgtgttaa cgccaagttg gtcaattttg tcaaacaaaa
     2161 taacccctcc tattaattta ggtttttttt acctttattt cttacacttt cattctataa
     2221 gatgtcacac gaaaaagcaa tctttttcag tattttttac taaaagttgt catttcggtt
     2281 gtgtaagcct tttttctttt ggatttcttt taatttttcc ggggtcacgt cattgccctc
     2341 aggatcgacg actttcattc cttcgatatg atgacgcata ccggaacgaa aagcttccaa
     2401 atactctttg cgcaagttga tttgttcttg ttcttcggct tttgagagac cattttcctt
     2461 ctttttacgt gcaagttcat tgatccgctc tattttttca ggtgacagca tgctcagccc
     2521 tccttttact ctccttcata ttatataaaa actgaaaaaa aaacaactag ataaactaaa
     2581 taaaatacga acattcgttt gatttagcgc tttttatatg gtactattta tttatcaagt
     2641 gaaagaaggt gtaccttgtg gcccgacaaa ctgaatcaag acaaatcgaa gtcttacgat
     2701 atatccatga acaagtaacc caaaaaggat acccgccgac tgtccgtgaa atcggggaag
     2761 ctgttcagct ttcttctact tctactgttc acggtcatct tgcacggctt gaaaaaaaag
     2821 ggtttatcca aagagatccg acgaaacctc gtgcaatcga gttgacaaaa caaggtttag
     2881 aaaagattgg gattcgtcca acaactattc cagtacttgg cgtcgtaaca gctggagaac
     2941 ccattttagc agtagaggat gcttcagact tctttccaat ccctcctaat ctttcttccg
     3001 aagaaggcag tctctttatg ctgacaattc gtggagatag tatgatcaat gctgggatat
     3061 tggatggtga caacgtgatc gttcggaagc aagaaactgc tcaaaatggc gatattgtca
     3121 ttgcaatgac tgccgaggac gaagcgactt gcaaacgatt ctataaagaa aaaaactttt
     3181 tccgtctgca gcctgaaaac gacttgctcg aaccaatcat cttagatcaa gtatctatat
     3241 taggacgagt agtaggactt tatcgtagtc atatctatta attgctacta attaaaagaa
     3301 aactttttaa aaagagtttg agacgttggt ctcaaactct tttttcgccc gggttcttct
     3361 tctttcaaat ttttatcact tccctcttta caaaccgaac aaatattcgt atactaaata
     3421 tacgaacaat tgttcgcata aattaaagag gtgagaattc atgaaatcaa tgagacgtct
     3481 tggcttagta ttaactgttt tgtttttagg tattattatt ggtaatttcg gcatacgtcc
     3541 agctttactt gtgtttgttc cgttatttac tttgtggttc atgttgtggg atgaaaagaa
     3601 gtaccgtcaa tctgagcggc gcagaattca tgaagatcat ttctatcatg agccctacta
     3661 cagatccagg caatcataat aaggattgac tgctaattat tcaaaagaca agaagttaaa
     3721 cttttacggg ggtgtgacaa aaatcggtca catccttttt ttcgaataaa cggtgttcta
     3781 aagccagttt ttcggtatta agtcaaattg cggaaaaagt gattttttaa acttctactg
     3841 gtctttgctt gtttccattt ataaaaaaat agcgaccctc aaaagtcaga tagagaatct
     3901 gacttttgag ggtcgcttta aaatcgcttc tttaagaata acatcaagaa tagcttcttt
     3961 tttctgctta atattccatt aatgtaatga tgtcatatcc tttgattttg tcgcgtccat
     4021 ggagatccat caattcgatc aaaaatgcgc agcctacgac tacaccgcct aattgttcga
     4081 tcagttcgat cgtcgctttg attgttcctc cagtagctag caaatcgtca caaatcagca
     4141 cacgttgacc tggtttaatg gcatccttat gcaatgtcaa tgtatctgtt ccatattcta
     4201 atccataagt cacttcgatg gtttctcgag gtaacttccc ttttttgcgg actggggcaa
     4261 aaccgactcc taactcataa gcaacaggac atcctacgat gaatccacgg gcttctggcc
     4321 caactaccat atcaattcgt ttttcttttg cataatttac gatttgttta gtagcttccc
     4381 gataagcgtc accatctgcc atcagtgggg aaatatctcg aaacacaatt ccttttgacg
     4441 gatagtcggg aatactggca atataatctt ttaaatccac tctttgtttc ctcctaggtt
     4501 gttaaccatt tctttatggt aggaatatcg ctcaaaagca aaaattcctc aactttgatt
     4561 ttattgagcc gtcgctggta taatctgctc tcagtcaaag gatgactttc tgggctagcg
     4621 actttttgta aaacaccgtt ctctattgta acaaatttca attcaaaaaa cacctgtatc
     4681 ataaaaatta ataatttttc agggatacgc aaatattgag ctattgcttt tattttatga
     4741 cgtatatcaa ttcgttcttg agaatggatc aatttaaaca attttgcgta ctgttctctt
     4801 gtgcctaccc cattcaaata ggcctcatca ggtgaaatcc ccatcagata aacacgattg
     4861 aatgaataag accgaaaaac ttctttcaga tccgctaaat catctggaca atccataaca
     4921 actagagagt ttggttttct tttttcaatt attgccttta cagaatctag tccttcgaaa
     4981 acaatcgcag cttcctggat aatctcaggc acgaatttca acgtcgaaga atcaaatgct
     5041 aaataaaggc taccttccga cgttcggctc tgttcacgga aacgttttgc ccgccaatca
     5101 aatacttgca gaccacccac agaaaaatca gataccatca gctgcggttt cttacgcccg
     5161 ttccattcat tgatcgaaag ctttcctacc acatctacct gattattcag cagttcttct
     5221 tcttgagtac caaaaccaaa agcgaccgca tcaagctgac tcgatgcatc ggaaaggaca
     5281 aatttcagat gctgttggtt tgctccgatt cttttgatat tttctgcttg gacttgtcga
     5341 aataaaaact gaggcaaagg attatccgta ccaaatggcg ccaatagttt cagctcatca
     5401 attcgctcta ctgttacttc atttggcagc aatacttcat caattctcaa ctcaggccct
     5461 ctcatcaagt caatttgatg atcgactata tattggttca tcttctcctg tagtatagtg
     5521 acattttcac ttggcatcgt taaaccgact gctgcatgat gtcctccgaa gtaagtaaat
     5581 aaatctcgca tctggtcaag catttcaaaa agattcaagg cttcaatact acgtccagat
     5641 cctttagctg atccatcttc ttttaaagta aggacaagcg ttggtttacc cgtttcattc
     5701 attattttcc cagcaacaat gcccaaaacg ccttcatgcc atcctcggtt taccaataga
     5761 tggatatgat tctccttatt gaccatcgct aatgcttctt gtgttatctg ctctacgatt
     5821 gcttttcttt cttcattgat ctcattcaat ttttttgctt gaacggatgc ttcctcttca
     5881 tcaaacgtcg caagtaacga gacggcagga cgtggatcgc ccatccgacc gattgcattt
     5941 agtctgggag caatcgaaaa accgatcgtt gtttcgtctg cgtccctcat ttttacgccg
     6001 ctttcttcaa atagcgcctg aagtcctatc cgttctgaat gatgaatggc atcgattcct
     6061 aatgaaacaa ggattcgatt ctcatcagtc aatgaaacta aatcggcgat cgttcctatc
     6121 gctactaaat ccaaaaattc tgcaggcggt tcttccaata atgcagaagc tactttgaat
     6181 gctactccga ctcctgccaa atctggaaat ggatagtgcc ccgctggatg acgagggtga
     6241 acaatcgcat aagcgtctgg taaattctca ggtagttcgt gatgatctgt aatgatcacg
     6301 tctacaccag cttgctgagc gtatgctacc gcatcatttc ctgctacccc gttatcaaca
     6361 gtgatgatca actggattcc ttcttcgatc ttttcttggt ataccgattg gtttggtcca
     6421 tacccatgct caaatcgatt tggcaggaat acttctactt ctgcaccaag taattccagt
     6481 gtttctttca ttaccgttgc actggtgatc ccatctgcgt cataatcacc gtaaacgagg
     6541 attttttctc cactgattac agcttcttgg attcggctga ttgctttatc catatcgtgt
     6601 atcagatacg gatcatgtaa ttcttgttcc tttggatgta aaaatcggtt gatatccttt
     6661 tcctcatggt aacctctttg ccacagtaac ttaccgacaa atggagataa tttcagttca
     6721 cggatcattt ggagaaagga ttcagaaggc tctgtctcgc ttaacttcca atcaaaattt
     6781 gcttgtctca ctttctcact cctaacttag ttattatagc aaaggaaatc agcaaaaaaa
     6841 agcagaaaga aagaataaaa acagatcaga tccgctagac agatgttcag caggacctga
     6901 tcttttgtac gaccatttat gaaatatccc tattagtcaa aataattgaa gctttgtttg
     6961 ggcgattgag ttttttgttc ttccggcgct ttcaattgac tgatttgtgc ggttttcgct
     7021 tgtaactccg cctgataagc agcttccaac tccgcacgtt cgtttctaaa ctcgcgttgc
     7081 tgttcttctt ttgcttcttc aattttcttt tgaagttctg tttgatattc tgacatttcc
     7141 tgagtcagct gtttgatttg ctttttttgc tgccatagtg ttgccgaagc agtcaaaaat
     7201 acaatcagtg caccaatcag cgcagaaccg atgatcacta agatcaatgg cgcagaaaag
     7261 gaagtgaagc caaaacttac aggaacattt ttattgttca atacagcaaa aagaacaata
     7321 atcaaaacta aaacaaatcc aagaatcaca ttgctttgct ttttcaattc cttcacctac
     7381 tttttgttaa aaattccgct ggctaaataa tcaccaatcg ttggaaacag cgtataaaat
     7441 tttgatgcaa cttctaaaat aaacggttga ttgatttccc gttttggatg tctcatattg
     7501 cggacgatca tttttgccaa cttggcaggt tctaaaacga tttgtccgac tttttccaaa
     7561 tagcttccgc ttggatcagc cttatcgaag aaatttgtct cgattggacc tggattcact
     7621 gtcgtaacag ctacgccaag tggtttcaat tctaatcgca aagcgttgga gaagccaagg
     7681 actgcaaatt tcgtggcaga ataaaccgtt gattttgcag ttgccatttt tccagccata
     7741 gaggcgatat taatgatatg accttgtctt ctttctgcca tatcgatcgc aaatttttgt
     7801 gtcaaaacca tcattcctaa gatgttgact tcaaacatat cgtatgcttt tccaaggtcg
     7861 aatgtaagga agtcttcgaa aatcccaaaa cccgcattgt ttaccagaat atcgacgcgc
     7921 ccgacttctt ccatcacctt ttcatataat tcgtccacgc tttcaggatt gctgacgtct
     7981 accttgaaag cataagcctc tttgccgctc aagcgtctgc actcgtctct gacaccttct
     8041 acaaatgcca ttcttcgtgc gcaacttata acgattgctc cttgctttgc tgcttcataa
     8101 cagatttgtg cgcccagacc gcctgaacta cctgttacta aaacaacttt atcttctaaa
     8161 ttcatgcctc ttcctcctcg cgaaatggaa tctcaatgct atcaaaatct ttcataatcg
     8221 tcgtgttttc aaacacttct tgtgcttctt tttcaagctc taaagctgct tttcctaaat
     8281 atctcgcact gatatgagta agtagcagcc gttttgcctg cgcttctttt gcaacttcag
     8341 cagcttgatg agtcgtggaa tggaaatagt tgtgcgccat tcttgcttca tctttattaa
     8401 atgtgctttc atgtaccaga atatcgctat tttccgcaag cacaacggaa ttatgtgttt
     8461 ttctcgtatc gcctaaaata gtcacgattc gtcctttttt atctggacct acgaaatctt
     8521 ttccattgat cgtccgccca tcttctagtt ggatcgtttc accttgcttc agtttgccgt
     8581 acagtggtcc agctggaata cctaattctt ttagacgatc cacctgcaat tctcctttat
     8641 gatcatgttc aaccacacga taaccaaaac tgtcgatccc atgatttagt ttttttgtat
     8701 aaacagaaaa ttgctgatca gtaaaaatcg gggctgtttc atttagctca atgaatttca
     8761 gcggataact taaacgcgtt tgcgaaatac ctaaagagac ttttatgtat tcctctatcc
     8821 cttttggccc gtaaatctct aatggcgtat ccccaccttg aaatgaccgg ctgctgatga
     8881 gcccgggaag tccaaaaata tgatcgccgt gtaaatgtgt aatgaaaatt ttaccgattt
     8941 ttctcggacg aatagtcgtt cgcaaaatct gcatttgcgt gccttcgcca cagtcgaaca
     9001 accaaacttc attgcgctcg tctaaaagtt tcaatgctat acttgtcaca tttctatgtt
     9061 ttgcaggaac acctgcacct gttcctaaaa attgtaattc cataatctac ctgactttct
     9121 ttaagttcct ctttaatttt agggtaaaaa gaagggataa tcaaccgtaa gtcgagaatg
     9181 ggttcaaatt aaaaataacg ttctaaagcg atagcgtttt ctttgaaaat tactataaaa
     9241 acagcagcga acccgtttga gatcctctgc tgttttttat taatttgaag atccagaact
     9301 ttcattgtcg ttggaagttt gcggatgttt gtccttccaa gtcttttgtg cagcttcttt
     9361 cgcatgattt tcagcttctt tcgcatcatg cacatctttt tcgacatctt cataatccaa
     9421 gcgagtaatt tctccgccta attccatcat taccaattga ttcagtgggc gattgtcctc
     9481 ttcatcagca atcaagatca gtcctgtagc tccttcaccg attttatttc ctacaaagtc
     9541 gaacacggtc tgggcatctt ttatttcttt ggcatcttgt gtcgcaccga tcattcctcc
     9601 ggcaaaccat cctaataaaa tccctagcgg accacctaat acaccaacca acattccgat
     9661 taatccaccc gtagaagatt tgttattacc ggtaaagtcg ataaaatctt ctattttgaa
     9721 ttgatgtgtc ccattaggat catggctgac aactgccatc tgttctcctt taatcgaacg
     9781 aacagcatgt aactttttga tttctgaaaa tgcctgatat gcctggcttt ctacttgaaa
     9841 atttaaaatg attactcgtt tgctcattaa aaacgcccct ttcatacctt cttgttattt
     9901 attttacctt taattgaaaa ataagaaaag aaaagcactc tttttttcca ataaaatagg
     9961 gctgtgacaa aagtcgtatc acagctcctt tttccgaata aacggcgttc ttgaagctga
    10021 tcacttctgt cacaacctcc cttaaatctg aatctatatt ttttggtatt tgtttttatt
    10081 tgcttgccta ttcgacaaat tcaaattcaa actcaccgat acgtacaagg tcgccatctt
    10141 tcgcaccgcg tgcccgaaga gcttcatcca cacccatacc acgtaattga cgagcaaaac
    10201 gcatcactgt ttcatcatga tcgaaattcg tcatttggaa taatttttcg atcttctcac
    10261 cagataagat ccacgttgca tctgaatcac gatcgatttg gaactcagga ccttctggat
    10321 tgaatccata gtgtacagtt tcttcttcca gttcttcttc gtacaatggg aattctggcg
    10381 ttacttctaa caaatctgct gtagcattca ataacgcgtc caatccttgt cgagtcactc
    10441 cagaaattgg aaatactggg atgtcatcag caaattcatc ttctttttcc ttgttcagct
    10501 gttctttgaa tttcactaga ttttccggtg catccggcat atccattttg tttgccacga
    10561 tgatttgcgg acgctctagc aagcgtaagt tataagtaga taattctttg ttgatggcaa
    10621 gatagtcttc ataaggatct cgtccttcca tcccactcat atcgatcaca tgtaaaatta
    10681 ctcgtgttct ttcgatatga cgaaggaatt gtgtacccag cccaacacct tgcgaagctc
    10741 cttcaatcaa gcctggcaag tctgctgcgg caaaacttct gccatcactt gtagtaacca
    10801 ttcctagatt aggtacgagc gtcgtgaaat gataagcgcc gatttttgga cgagcagatg
    10861 aaataacgga tagtaaagtc gatttcccga cagatggaaa acctacaagt ccaacgtctg
    10921 ccaatacttt caattctagt tcgatttttc gctcttgtcc tggttcaccg ttttcagcaa
    10981 tttccggtgc aggattccga ggagaggcaa aacggatatt ccctcgtcca ccgcgtccac
    11041 cttttgccac aactagtgtt tgaccatttt caattaaatc tcctaaaaga gcaccagtct
    11101 ccgcatctcg gacagtggtt ccttgtggta ctttaacata ggtatcttct gaaccacgac
    11161 cgtgcatccc tttactcatc ccattttcac ctggctgcgc tttgaaatgg cgattgaacc
    11221 gaaaatccat caatgtacgt aacccttcat cgacgatcaa gatgacatcg ccgccacgac
    11281 caccgtctcc gccagccggt ccgccgtcag gaacgtattt ttcgcgacga aatgcaacca
    11341 ttccgtctcc gcccttgcca gctttcacat cgatcgttac ttgatctaaa aacatggaca
    11401 taattaagtc ctcctattat tcatttattt atttgactgc ctgaatttcc acaataaaca
    11461 aaagtcttac ttattttatc ggtgaaatct gattttgtct atcatttcag caaaaagatt
    11521 gtttaccttc ttcttttttt atcatttggt aaggtttcca accttttttc tgctaccaag
    11581 tataattttt tgacaaaata ttctttgcgt agcagaataa cagtgtatta attgtattaa
    11641 ttgaggatgc cgtttcacag cacccctaat aaaggaggaa cttttgatat gacagtaaaa
    11701 gtaggtatta acggatttgg gcgtattggc cgtctggctt tccgccgcat caaagaagtc
    11761 tcagatgata ttgaagtagt agcaatcaac gacttaacaa gtccaactat gttagcacaa
    11821 ttattgcaat ttgactctac tcatggtact tatcctggca cagttactgc aacagaagac
    11881 tcaatcgtag tggatggcga agcaactcgt gtttatgcag aacccgacgc aagcaaaatc
    11941 ccttgggcaa aagaaaacgg tgtagatatc gtactagaat gtactggttt ttatacatct
    12001 gaagaaaaag caaaagcgca tttagatgct ggtgtcaaac gagtagttat ttctgcccca
    12061 gctggtgcta tgaaaaccat cgtctataac gtcaatgatg atacattaga tgaaaacgac
    12121 aaaatcatct cagcaggttc atgtacaaca aactgtttag cacctatggc ttatttctta
    12181 aataatgaat ttgggatcga agttggtaca atgacaacag ttcatgccta cacttccaca
    12241 caaatgctct tagatggacc tgtaaaaggc ggtaatttgc gtgctgctcg ttcagctgct
    12301 gacaatacta tcccacattc tactggtgct gcgaaagcaa tcggcttagt tatccctgag
    12361 ctacaaggaa aattacaagg acacgcacaa cgtgttccag tcgttgatgg ttcattaact
    12421 gaattggttt cagtattgaa aacaaaagta actgctgatc aagtaaacga agcaatcaaa
    12481 aaacacacag ttgacaatcc ttcattcggg tatgatgacc gtcaaatcgt ttctagcgat
    12541 gtcattggaa caactcaagg ttcgatcttt gacccaacgc aaacagaagt aacaactgct
    12601 ggtgatttcc aacttgttaa aactgttgca tggtatgaca atgagtatgg atttacttgc
    12661 caaatgattc gcttactaga aaaattcgct aacttgtaat ttgatagatc aatcgataaa
    12721 agaagccttt gactggatcc agtcaaaggc ttctttcttt tcatccccta cttttaaact
    12781 cgttcaatga acatattggc ttaaaaattg ttggactact tgctgatatt tttcaggatc
    12841 tgtcttgtat gcttccgcat gctcggctcc ttttacaaca tacttttctt ttggtccctt
    12901 cgttgcacga tagaccttat ctaacatttc aaatggtaca aatgtatctt cgtctccatg
    12961 tataaagagc attgggcgct ggtttttctt caattgttcc actgcatttg cttcaccgaa
    13021 aaagtagcca gcacggactt ttgtcactag actcgttact tgcataagcg gaaatgctgg
    13081 aagactaaac atatcgtcta gctgataagc aagctcatca tgaacggaag aataaccgca
    13141 atcttcaatg attgctttca cattatctgg tagtttttct ccgctagtca tcataactgt
    13201 tgctgctccc atgctgacac cgtatagaac gatttcttgc gattttccat tgttttctag
    13261 cactttgttt atccactgta catagtcttt acgctctggc catccaaatc caatgtaatc
    13321 cccttcgctt tttccatgtc ctcttgcatc aggaacaagg acattgtaac ccatatcatg
    13381 aaacatcttt gcgtaattgg tcatcgtttc agcgtttccc atatagccat gagccacaag
    13441 agctgttttt tcacttttcg tttcagcagg aagataaatc gctgataatt tcagaccgtc
    13501 ttttgaagtg atggtccaat cgcttcggtt ttcttttgaa ctaaaccatt tatgtgcatc
    13561 cgtttctttg gatgtctgtg ttgtaccagg tgtatcttcg tctaaaaagt ctttctcaga
    13621 aggcacaaca gcataattat aaaaataatt ccctgcaaac actaacgcaa caatcagagc
    13681 taaagcgacg cctaaaagga ttttcatcca aagtttcata aatcatccat ctcatttctc
    13741 ttttttcata taaccttgaa ttagtataat caaagaatct ctactatgca atgttcattt
    13801 ttataacccg cgaattgtaa aattaagtta gaaaaataaa aaggcattta tggtacactc
    13861 aaattgtatt tccgacgaaa gaaaacaaag gagtgtaacc ataaatgacc tacaaacatc
    13921 ttaccataga cgaactgaca atgatagaat catattatct tcaacataat aagccggttg
    13981 aaatcgctaa ccgaatggga cgtgctatac aaactattta taatgtagtc aataagttca
    14041 agcaaggcaa gactgctctt gattattggc accagtataa agaaaataag aaaaaatgtg
    14101 gtagaaaagt cattcaatta cctgctcatg aagtagatta cattaaagag aaagtcactc
    14161 ttggttggac gcctgacgtc attatcgggc gaaaagaaag gtctgtttca tgcggtatga
    14221 gaacacttta tcgtttattt tctaaaggaa tatttgatat tgacacacta ccgatgaaag
    14281 gtaaaagaaa acccaatggc catcaggaaa aacggggaaa acaacagtat cagcgctcaa
    14341 tccatgatcg acctgataat tatcctgatt tcaattctga gtttggtcac cttgaaggtg
    14401 atacgatcgt tggcattcat cataaaagtg ccgtcattac tttagttgaa agattatcta
    14461 aagtcattat cacgattaaa cccaacggcc gtaaggcatt agatattgaa actgccctta
    14521 atcaatggtt ttctcgcttc cctaaaaact tctttaaatc tattacgttt gactgtggaa
    14581 aagaattttc taactggaaa gccattagta accaacatga tattgatata tattttgcgg
    14641 accctggaac accttctcaa cgcccattaa acgagaattc taacgggatt ctgcgtcgta
    14701 atggactgcc gaaatcaatg gattttagaa aagtgaatca gacatttatt tccagtgtca
    14761 gcaatcaacg taatcatatt ccaagaaaat cattgaatta cagaacacca atcgaaatat
    14821 ttttgagcta tgtacaagaa gcattttatt ctagcttaat ttgacaaatc ataacctata
    14881 aaaaaacaaa ataaaaaagc agaaataact ggctatttct agcggattat ttctgcaata
    14941 actaattatc tattttttat tttcaattaa tttaaagctt gaccatggtt tcaaaaagtc
    15001 aaggaggaat aattcgtcat cggagattct tcctacaaca ttgacacgtc cgtcgttttt
    15061 catatccttc aaggcgattt gtgtttctcc tttgtattga ccgtaccctt cattgtcaat
    15121 cagtacatcc ccatgatgca tatctcgcgt attatgaggc gggaaatctt tatctttgta
    15181 gtatacacga gtcatcgttg aacgaaggat atattctgag cgatcccctc gataactatg
    15241 aaggttatca aacaagcaga ttcgttcgtt ttctgtaata ccttcttccg tatctacttt
    15301 caatgttgga taatccgcgt taaatgcttc tgccatttct ttcaattctt cttcacttgc
    15361 gtacgcattt ccaatagaaa tatcatcaat caatcctgta aggattaaat gcttcacttg
    15421 tgtcgcaatt tcaagatctc ggtggtcttc cagcgtgcac aagccatctt gcgtaggcca
    15481 agggccaaac tcagcagatt gcgaattgac gaatgccatc gtattcaaat tatattttct
    15541 gaatttttct gaacaaaaaa caaagtgttc gtatcctaaa ccagagtatc gatgaggata
    15601 aaaattatga gaacctaata aattatccgt gtttggcgaa taactcatga tgttgtcaac
    15661 gtaattcgtg cccgaactca tattgatctc gattttgata ccaaaaggat tgcgcgtcat
    15721 ttttgcttct tctgctcctg tgaatccgat atctaagcgg accccgtagg cacccatctt
    15781 atggaaaaaa gataagtcat cgtaagaaat ctccaactgt tcaaataacg ctggattgat
    15841 atcaaccatt acttccatgc ctaggctatt cgcgtaatca actacttctt taaattctga
    15901 aagaactttt tctttatcat cattgatctg cagcaaactg gtaaaaaccc gtttataccc
    15961 atacttatga gctaaatcca agtacgcttt gtccttttca aatgttgacc gttctggata
    16021 aatcgagatt cctaattttc ccatattacc atttcctcct gcatcttttc gtttttgtat
    16081 ccacttacat tatagcaaac acaaagtaaa tggtctacac cttttctttt tcttttaaaa
    16141 taaatgataa attccaataa tttaagtagg tattttccct ctattttgtt atcattaaag
    16201 ataacaaaat agtaaattgg aaaggaacag ttatgaagaa aaataaagtt attttaagta
    16261 ttagtttagc agcagcattg ctgtttgctg ctggttgttc tgcaaacaac acgacttctt
    16321 ctagttcgtc tacagaaagt tcaaaaagta catctactgc ggaaagcacg actgccagta
    16381 gcgtcgattt gaacgcattg gaattaccac aattgacgaa agatgtcgcc gaaaatgaag
    16441 atctggtcga aatggtgacg aataaaggca caatcaaaat caaattattt cccgaacacg
    16501 caccaaaagc ggttgaaaac tttatgacac atgcaaaaga cggttactac aacggactga
    16561 ctttccatcg cgtcatcaaa gatttcatga tccaaggtgg cgatcctaaa ggcgatggca
    16621 ctggagggga aagcatttgg ggagaaggat ttgaaacaga gatcaacaac cacctttata
    16681 atataagagg tgcgttatct atggctcgct cacaagatcc taacagtaac ggcagccagt
    16741 tctttatcgt tcaaaataca gatgatatgc atgatggtct tttaaaagac gactatcctc
    16801 aagcaatcat cgacgcttat aaaaacggcg gttatccttc actagatggc cattatactg
    16861 tcttcggcca agtgattgaa ggaatggatg tcgtggatgc tattgcaaat atcgaaacag
    16921 atagttcaga caaaccaaaa gaagaagtaa aaatcgataa aatcaatata ctgcaagaag
    16981 caaaacaaaa ataaaaaaat aacgtctgaa tcctgcatag atgacaacgt atgctaggat
    17041 tcaggcgtct tctttttaca taaaaagcaa gtaagcttcc ttttgttttg ctatatcagg
    17101 ttttatagtc aagcattttg gttgacgatg aacgtgaact cgcactcaca gactttttta
    17161 tcatctacat atgctgcaga taacgctgta ccgactgatc ccttcatttt ggtgatttca
    17221 aaatgacatt tcagcacatc tcctggaaca actttttgac ggaatttggc cttattgatc
    17281 ccaccgatat aagctctttt tcctagaaac tcttctgatt ttaggataag tatcgaacct
    17341 gcttgtgcca gtgtttctag aatcaacgca cccggcatca ctggattgtc aggaaagtga
    17401 ccttggaaaa aatcttcatt gattgttaca ttttttgtcg caacgatctt ttttcctggt
    17461 tctaaagtat ctacataatc aatataacaa ataggataac gattaggaat caattccatt
    17521 acttcagtag cagataatac gtaagacata attaaactcc ttctttcagg caattgccat
    17581 tttcattact ttgactatca aagtatcata ttcctaaata tttagcaatc tttttttaat
    17641 ttaagaaaaa atagtttgac aatcaaaaca ttttgactaa taattaagaa atcaagaagt
    17701 tattttagct attattctct atttttttac gactatcaaa tttttatcag aaacaaagga
    17761 gagtcattat gtcatttcta gaaggaaaaa aaatcgtcat tatgggcgtc gctaacaaaa
    17821 aaagcattgc ttggggttgt gctgaagcaa tgttgaaaca aggggcagaa attatctata
    17881 cttaccaaaa tgaacgaatg aaaaaatcat tagtcaaatt ggtcggcgaa gaagcattca
    17941 ctgtagaatg tgatgtttct agcgacgaaa gcatcgaaaa agcaatgaat gccatcggtg
    18001 aatatgctgg ggagatccac ggccttgtcc atgcagttgc ttacgccaac aaagaagaat
    18061 tgtccggaaa tgtgtctgat atttccagag acggctatca attagctcaa gatatcagca
    18121 gctactcttt aattgctgta tcaaaatacg cacaaccgtt tcttgcacca aacagcggga
    18181 tcgttagcat gacttatcta ggttcagaac gcgcaatccc gaattataac atgatgggta
    18241 ttgcgaaagc ttctcttgaa gctgctatcc gttatttggc agctgagttc tcgcctaaag
    18301 gaattcgggt caatggaatc tcagctgggg caatcaaaac attagctgtc acaggtgtta
    18361 aagactatca aaaactgatc cagttatctg aatctcgtac gcctgatcag caaggtgtga
    18421 cgatcgaaga agtcggtaat gcttgtgctt tcttaatcag cccactttcc agcggaatca
    18481 tcggtgatat tatctacgtt gacaaaggtg tccatctttc ataaactttt gttgcattct
    18541 ttaaagtaaa acatataaaa atcaggaaaa aactttttaa agtctcttcc tgattttttc
    18601 tttttacgtt tttttcaact cattactttg aaattattcc acgacttcaa tccagccttc
    18661 tggtgcttct atgtctccaa attgaatacc tgtcaattca tcatacaacc gttttgttac
    18721 tggtcctact tccgtttcac tataaaatac atgaagattg ttattgtgat aaatcccacc
    18781 gattggagaa ataacagccg ctgtaccaca tgcaccagct tctgcaaatt gatctagatc
    18841 atcaatgaaa atatctcctt caattgcttg cagtcctagt cgttcttcag ctaactgcaa
    18901 caaggaatat ttcgtgatac ttggtaagat agagggcgat tgcggagtga tgaattttcc
    18961 gtcttttgta attccaaaga aatttgctgc acctacttct tcgattttcg tatgtgtggc
    19021 tggatcaaga taaacacaat ctgagtaatc cagttctttt gcttctgttc ctggaagtaa
    19081 actcgctgcg taatttccgc cgacttttgc tgcaccagtc cccttaggag cagcacgatc
    19141 gtaatcagat acaataaaat tcgttggttt tagtccacct ttgaaatacg ctcctactgg
    19201 cgtacagaag acgacaaata aatattctgg agctggatgg acaccaatgt tttcaccgac
    19261 cccaatcagt aaagggcgca agtataatgt agcgcctgtt ccatagggcg gcacaaaatc
    19321 ttcatttgct tttaccactt gcttgacagc atcaacgaac atcttttcag ggaccattgg
    19381 catcagcaat cgtctagcac tttgattcat ccgtcgacta ttttgttcag gtcgaaagag
    19441 attgaccttg ccgtcttttc gacgataagc ttttagacct tcaaaacatt gctgaccata
    19501 atgaagcgct ggagagcctt catgaatcgt caggtaatta tcttctgtca attctccttc
    19561 ttcccattgt ccgtctttcc atttggcaat aaaacgccaa ggagttttga tataagaaaa
    19621 acctagattg ttccaatcga tttgcatata cttaccacct tcgttatttt ctccacattt
    19681 tatcattatc catattattt gtcattttat tttcagcttt tttccttcat tatagttatt
    19741 tttgctattt ccttttttga aaacttcttg gtacaataca gaaagaatca aattttagaa
    19801 aagaggattt tatgttttca ttattagcaa ctgccggtac gacagactct tctggcgaga
    19861 cattgacaga tcaagctgtc agcaaagtaa atgcgtttca gcggttttgg gacgggattg
    19921 attgggacgc cattttggct gcctttatcc aaaaaagttt atatctgatt tttttgatcg
    19981 tccttttttg gattcttcac cgtgtgggaa aatatctgat tgataagtct tttaatcagt
    20041 attctaaaaa agccattcta aacgagagcc gcttaaagac tttacatagt cttttaaata
    20101 ctatttttca ttataccctt ggtttctttt ttatctatgc aattttatct gctatcggtg
    20161 tgccgatcgg atcacttttg gctggtgccg gaattgcagg tgtggcaatc ggtcttggtg
    20221 cccaagggtt catgagtgat gttattaccg gattttttat tatcatggaa caacagatgg
    20281 atgttgggga ctacatcaag ctagcaaact taacgattga aggaaccgtc gtatctgttg
    20341 gtatccgtac ccttcagctg aaagcaacgg atggtactgt ccatttcatc ccgaatcgaa
    20401 acatcaccac gatcagcaat ctctctcgtg caaatatgca agtactttta gatattcgga
    20461 ttgttcctga agaaggatat gacaaaatct atgagatcat tgatcgagta aatcgtacat
    20521 tagctgaaaa ataccaagaa gagctccaaa ctgaaccttc tatctttgga ttagtggatc
    20581 ttggaaacag caattttgcg attcgtacgg tctgctacgc attgaacgga aaacaatatg
    20641 ccttaaaaga agagttcttg agctcctatg tcaaagaatt gacagcttct ggtttcacga
    20701 ttccgaacag tccaattgct gtcggaaaat aatttggaca aacgatgcaa cgaatctcac
    20761 taaaaagagc gtgggacaaa agtaaagaac acttttgtcc cacgctctaa acacgtataa
    20821 acggcggaag cagaagcaac tccttcggaa ataagctgaa attcacaaaa atttgaaaag
    20881 caattttcgt gaattccttc ttatttcttg gagttaaacg cttttgtccc agcctctttt
    20941 tcaagataaa gtcaaaactg gtacgctgtt ttttctactt attttttgat tatcttttag
    21001 tttctcgttc tttagctcac gatatcgatt tgttctttta attcttcgat tttcggagac
    21061 aatatattac gacgttctaa ttcatgcacc atgaagttta cggctttaag cagctctttt
    21121 cttgtaatga ttcctttgaa aatccgatct tctgtgacaa ccggtaaaaa aggcgaatcg
    21181 actaacaaat ggagtacttc ttctagttcc caattttcat caattgtcgg aacatctgtt
    21241 tctgtcacat cagcaaccgt tagtccttct aacgggtcca tgctgattgt ttgcaagtca
    21301 atcattttat tgaccacatc tgataaactt actagtccta caaagtgatc atcttttcct
    21361 aatacaggaa ttttggaata accgaccttc gataacacaa gtaaaccatg ggacaatgga
    21421 tgatgataca taacatttgc cacattttct gcaggaatca aaaacgtttc ctgattttcc
    21481 agcagcattt ctcttactat aggtccaatc atctgatggc ctccatttct atttcattca
    21541 acactactat tttaccgaaa ccggatgcaa aattcataaa ataaagctta tttttattaa
    21601 aaattagagt ttttttattc agcgctctct cgaaaaagaa aaggccaact cttcaactgc
    21661 ctgatgggca cggttatagt attgaacaga aatttggtca tctaaacttt cgataagagc
    21721 atatgatggg atttggatcg ggcctctagg ctgagaaatg ctaccaggat tcaaaaacag
    21781 gattttctga tccatctcac agcctatttg atgggtatga ccaaaaaaca ccatatcggc
    21841 agttgcagct cgagcttcga ttgctaactg tgtcaaacca aatcggacat tcgataaatg
    21901 accgtgagtc atgaatactg tatcctgacc agtttggatc acttttttct gttcgaatcc
    21961 tggtccataa tcacaattac cttgaaccac ttggaatgta tcccataatg ggtcagaagc
    22021 ttctaattcc gaatcaccac aatggaaaaa gatatccact tcagaacgat aacgatctac
    22081 taagtcaacg aggatatctc tgtctccatg attatcactt actactaaat accgcatcta
    22141 tctctctcct tccagccatt gtttccactc ggcactcaat tttttcattg cttgagcccg
    22201 atgactgatc ttgttttttt cttcgctcga taattctgct gctgtttgtt tcttaccttc
    22261 tgggataaat aaaggatcat acccaaagcc attttcgcca gatggtatac gggctactcg
    22321 accgggccat tccgcttcta ctacaaggct gtcttttttg ggtgccgcga atactaacgt
    22381 acaatggaat tgtgctgttc ttttttcatc cggcacatct gtcaattcat ataataattt
    22441 ggcgttattc cccgcatcac ttttttgttc ccctgcaaaa cgtgcagaat agattcctgg
    22501 cataccgcct aaagcatcca ctttcaaacc tgaatcatct gctaagactg gctgatcaag
    22561 caattgtgca atcgtttctg cttttaatcg ggcattttct tcaaatgtgc tgccagtttc
    22621 ttccacatct ggcaattcag gatagtcaag taatgttttt acatgatatc ccgcttcttt
    22681 gaacatattt cgaaactctt ctgcttttcc tggatttctt gtcgcaatga tgattgtttt
    22741 tgtttcttct atccgctcat cattttgagc aaactctgtt agcaaagcat gtttttgctc
    22801 tttgatcaaa tcttcaatcg cgttttttcc aaaaaagagc atttcattca actgttcacc
    22861 atcaaacgtt gcttcttctc cagttccttg aatctccacg aattttccag attctgtcat
    22921 tacaagattc atgtctacaa gtgctgcgga atcttcttgg taatccaaat ctgtgacgca
    22981 agtcccatct ggtaagattc ctacgctaac tgcagcaaga tgttctttta ttggatcttc
    23041 tgacaattct ttttctctta aaagtttttc aatggctaat ttcaatgcca caaatgcccc
    23101 agtgatactt gctgttctag taccgccatc cgcttggatc acatcgcagt ctacgatgat
    23161 actacgttct cctaattttt ccaagtctac tactgcacgc aaggaacgac caataagacg
    23221 ctggatttcc attgttctac cagaaagttt ccctttgctg ctttctctac gatttctcgt
    23281 actcgttgct cgaggcagca tactatattc tgctgtcacc catcctgttc ctgtttctct
    23341 caaaaaaggg ggaacagaat tttctattgt tgcagaacaa ataactgttg tatcaccaaa
    23401 acggatcact accgatcctt ctggatattt gaaaacattt gtttgaagct ccagtttgcg
    23461 aagctcttgg gcttttctcc cgtcatgacg catccttatt ttcctcccaa ttcgatatgt
    23521 tctacattta agtgtccgat tccaagccag tcttcagcta tttcctcgaa aagtttggca
    23581 gagccagttg tataaaactg gcataatgtc cgaccatttt gcggtgaatt gctcaaattg
    23641 aaataatcta acagcataga tacttcacct actgtttctg ctccagaatc gatcagttga
    23701 acattttctc ccattacatt ttgaatgatg gggcgtaata atggataatg ggtgcatccc
    23761 aaaatcaatg tatcgatttt tttagtggtt aaaggagcta atgtttctgc cacaattttt
    23821 ttcgccaccg atgaatggta ttcattactt tcgacaactg aaacaaattt gggacaagca
    23881 agacttgtca cagtcaattc tggtactttc tctttcagtg ctttttcata agcttgactt
    23941 tttaccgtac caatcgtacc gataatgcca acttgtttat tttgtgtttt ttttactgcc
    24001 gctctagtac cgggaaggat cacaccgatg actggaatag aaagagcagc tttgatttct
    24061 tctaaagcca ccgcagttgc ggtattgcag gcgatcacca gcatcttgat tccttgctcc
    24121 accagataat ccgtcatttc ccaagtatac tggattacct gttccgcggg tctagggcca
    24181 tatgggcagc gtgctgtgtc tcctacaaat aaaatatttt cattcggtaa ttgtttcagg
    24241 gcttctttta ctacagtcaa gccgccgaca cctgaatcaa taaatccgat agggcgatta
    24301 tctgtcaatc gtatcatcct ttttttcaat aaattctatc ctccctattg tgtacttttt
    24361 agcgtgaatt ttcaagtgct cttacttgct taaaacaatc gaaatctctt tttttcgaat
    24421 ggaaagagga aaagcggttg tgactttagt ttgccacaac cgctaaaaga atcatctatt
    24481 aataactgta ccgtctcttt tccaagtaac cggaaagcag agaaagcgcg taacatacca
    24541 cgaagtacat aagtgtcatg atgatgaaca tcggaagcac ataattggtg ttctgtccat
    24601 aaataatacg tgcctgatga gaaagttcag gtaaagaaat gattactgct aatgaagtat
    24661 ctttgatcag tgaaatcaat tggctcacaa ttgccgggat cattgattta aatgcttgcg
    24721 gtaacacgat cgttcgcatc gattctacat aagtcagtcc cgttgataat cctgcttcca
    24781 tctgtccttt tggaacagca ttgagtccag ctcggaaaat ttccgacaac atagctgact
    24841 caaaaatcgt taatgctgcg acagcggacc agaagatgtt catctgaatg ccgatttgag
    24901 gtaaggcaaa gtaagtgaag aaaatgatca ataataatgg aagattccgt ataatatcaa
    24961 tcactacacc aaggattttg gaaaagaaag ggatattcgc aaaacgaatc acacctgtca
    25021 gaccaccgat caagaaacta aaaatgatcg aaaacaatga aacttcaaca gtaaccttta
    25081 atccttccaa taaaaaacgg atattcatcc atgaaaaagc gccgctaaaa tccatgtatt
    25141 tcccctcctt ctatgaacga accgcccatt ttttctcaag ataaaccatt aagtaagata
    25201 acggtagcgt gataactaag taaaataacc caacgatgat atacgtatcg aaggtattga
    25261 atgtttcact agcgatcaag tctccttgat acatcaaatc taaaccagct acgattgcta
    25321 aaatagatga gttttttacg aggttgataa attggttgcc taatggcggg ataacgattt
    25381 tgaatgcttg cggtaaaaca atataacgca tgatttctga ataggtaaaa ccagaagata
    25441 gtcctgcttc tgtttgacct tttggtacgg tttgaatccc tgaacgtact gtttcagcaa
    25501 taaaagcaga tgtatagatc gttaatccaa tcgtacctgc ttggaatcca tctagattaa
    25561 accaataaat cggtacgaca acataaaaaa acatcacgat gattaataat ggaatgtttc
    25621 taaaaaattc tacatatgcc tttgctaagg cgctcactac tttattcttt gataattgga
    25681 agattgccat taacgttccg ataatcaaac taaacacaag tgctaagaca ctcgaaaaca
    25741 atgtgatctt gaacccgtcg acaaagattg gtccataagt ttgtatcaat tcgctcattg
    25801 cctctccccc ttactctact tttccttcag tttcatttgg aaaccatttt tgatagattt
    25861 tatcgtatgt gccatctgca tgcatttcct ctagcgcttg gttaacagct ttcaagaagt
    25921 tttcttgccc tttgttgatc gcaatcccgt aaggctcatt agtaaacgtt ccaccaacta
    25981 actcatactc tggattttca tctgcaatcc ctaacaaaat cgcattatcc gtagtcatcg
    26041 cgtctccctg accagattgt aaagcagtaa atgcttctgc atagttttct aattctaaaa
    26101 tttttgcatc tggtgcatgc tgtcggatat tcgcagccga tgtagaacct ttgactgcta
    26161 gaaccgttgt agaagcattc aaatcatcta cacttttgat ttggcttcct ttctttacca
    26221 acaaagcttg gccagcatcg aaatagacat ctgaaaagtc aacctgtttt tttcgttcat
    26281 ctgtgatcgt catcgttgca ataattgcat cgatatttcc gtttttcaat aatggaatcc
    26341 gagttttaga agtgacttca acaaattctg tttttccatt gtcaccaagg atctttttag
    26401 tgattgcttt tgcaatatct acatcaaatc cttgtacagt tctgctctca atatccatca
    26461 ttccaaataa tcgagtatca tacttgacac cccagatgat ttcattggta gatttgcttc
    26521 gctctaaaat atcttcattt gccaacccat ttcctttaca tccggctagt gcaagaaaag
    26581 caatgcctaa aaggaaaatc aggcgtattt tttttaacct gcgcatcttt ttcctcctat
    26641 caatgattga taactttact gataaattgc tgtgctcgga cttcatttgg attttcgaaa
    26701 aagtctctca catttctgct gtcttccaat acttctccat cagccatgaa gataacacga
    26761 tccgccactt ctttggcaaa gcccatttca tgtgtcacga caatcattga cataccgtca
    26821 tgagccaatt ttttcataac gtctaataca tcaccaatca tttccggatc caaagcagaa
    26881 gtaggttcat caaacagcag catctcagga ttcatcgcta aacctctggc gattgccacc
    26941 cgttgctgtt gtcccccgga taacatggaa ggataagaat ctttcttatc taacatattg
    27001 acagttttca aaaatttctc cgcgtttttg actgcagttg cctggtcttg cttcaacact
    27061 ttgattggtg ctaatttgat gttttccaga acagttttat ttgggtacaa attgaaatgt
    27121 tggaaaacca tgccgatgtt ttttcggact tctgtcagtt ttgtcttttt atcatgcaag
    27181 tcagtatcat taatcagcag cttacctgaa gagatcgtct ctaatccatt gatacagcga
    27241 agcatcgtgc tctttcctga accagaagga ccaatgacaa cgacaacttc tcctttctcg
    27301 aattcgagat tgatattttt taatgcgtgg aacttgccat aatatttatc cacgtgatca
    27361 aatttaatca ttgccataga attacactcc cattattatt tagtaagatt tcttttaaag
    27421 atgtataata aaatacatta tatctgatag tttagtaatt tgtaaagttt cttagaacgt
    27481 ttattctccc ataaatattt cttccatttc taatctatta gttattttat cctctttcct
    27541 tgttttttcc ttaggaactg ttgtttcttt tcaggaaaaa cggtaagata ttaagtgctc
    27601 agacttacaa atcgtaaaga ggtgtctttt ttgaaaaata ttattttaac gggagatcga
    27661 ccaactggga agctgcattt agggcattac gtcggttctc taaaaacccg agtggctatg
    27721 caggcagatg aagacaacca actgtttgtc atgattgctg acatgcaagc actgacagat
    27781 aatgctaaaa atcctgagaa ggtttcatca aatgtcttgc aagttgcttt agactattta
    27841 gccgtgggat tagatcctgc aaaatctact ttatttatcc aatcacaaat tccggaatta
    27901 gctgaattaa ccatgtatta tttgaactta gtcagcgtag gacgcgttcg gcgcaatccg
    27961 actgtcaaaa cagaaatcga acaaaaaaaa ttcggtgaaa gcgtgcctac aggattcttt
    28021 atctatcctg tttctcaagc agcagatatc actgcattca aagcgaatct tgtacctgtt
    28081 ggtgaggatc aaaaaccaat gctagagcag acacaggaaa tcgtacaaag cttcaatcat
    28141 acatatggtg aagtcttggt ggaaccaaaa ggcgtattcc caccaaaagg aatgggtaga
    28201 ttacctggaa tcgatggaaa tggcaaaatg agtaaatcgt taggaaacgg tatttatatc
    28261 tccgatcctg ccgatgtctt acagaaaaaa gtcatgagta tgtatactga tccaaaccac
    28321 atccatgtac aagatcctgg acaagtagaa gggaatatgg tcttcaccta cttggatgta
    28381 ttcggaacag ataaagaagc aattgaagaa atgaaagctc attaccgccg cggcggactt
    28441 ggtgatgtaa agatcaaacg atacctcatt gatgtattgg aagctgaatt tgcaccgatc
    28501 cgtgcgcgcc gagaagaatt ggaaaaagat ccttcagctg ttatggaaat cttacgtaaa
    28561 ggtagtgaag aagctgctaa agtagctgca caaacacttt ctgaagtaaa atcagcaatg
    28621 ggaatcaatt acttccatta attcatttac tctaaaaaag caggctgtaa aggcctgttt
    28681 ttttatctcg tctctgtgct attccttttt taaaatcaaa aaaagagatg tgacgaagtt
    28741 gtgtcacatc tttttttcaa atgtatggtc ttcaaaagct acttgatcgt tacttactat
    28801 attttccttc ttagcgaata cttgcctcta ggttttctac caacgctttt tcgacttttt
    28861 ccattgcttt attgatttct tcatctgtca atgttgcttc tgggttgacg aatgtcaggc
    28921 tatacgccat ggatttatgt cctttttcaa tgttttctcc ttgatagaca tcaaataatt
    28981 ggatatctgt taaaaatctt ccggcagcag aacggataac ttctgttaat tcctgatttg
    29041 tcacagtttc ttttacaagc aaagcgatgt cccggctgac tgctgggaat tttgtcactg
    29101 cttcgaaaac gatccctttt tgagcagctt ccactatagc agataaatca aactcagcaa
    29161 catatgtttc tggaatatca taactttttg taatcgttgg atgcacttga ccgacaaaac
    29221 caataaattt ttcgccaagg taaatcgcag cagttcttcc aggatgcatt tccttcattt
    29281 ctgtcactgt ttgataatgg acatcttcag tgatgcctag ttgttcaaat aagttttcta
    29341 aaagaccctt gatggtgaaa aagtctacat tttgagcttt cgtctgccaa tctttttctt
    29401 cccaaatacc agaaatagcg attgctgcat gttttacttc ttgcggcaga tgtgtacgtg
    29461 gatcattttc ttggaagaac acccgaccaa tttcatataa agcaatctct gtattttttc
    29521 gggcagtgtt ataactgata tcatctaata gtccgctgat caaattcatt cgtaatacag
    29581 aacgttcttc gctcattggc cagtccaaac gtgtaatatt actttcattt ataacaaact
    29641 gtcttgattt ttcttctgtt gtcaatgcat aactgattgc ttcgctcaat ccgcttcctt
    29701 caaagattgt acgaatttta cgagtagttt cttgttcttt tgacaagctt ccagcaaccg
    29761 tttctccact tggaagtgta gatggcaact ggtcgtatcc ataaatacga gcaacttctt
    29821 cgataatatc tgcttcgatt tggatatccc agcgtcttgg tggtactact acggaataaa
    29881 catactcctt ttcttcatag ctaaatccaa gtgcttcaaa aatctcattt acttctttaa
    29941 cgacaagaga tgttcctaaa tattgattga tgcgttcaag tgaaatcttc actgatacgt
    30001 cttctgcttt gatctctgag cctttgaccg cgccttgtag aacttcccca cccgcaagag
    30061 aaacgatcat tgctgcagca acctcactgg cttctccaac agtcgcatgg ttgattcctt
    30121 tttcaaaacg tgcagaggat tcactacgca aattaaattg ttttgctgta cgacgaatcg
    30181 aaattggatc aaataaagca gattctagtg caactgttgt tgtttcattc gtgatctctg
    30241 agtctaaccc tcccatgaca ccagctaaag caactggttc tttgccgtta gtaatgacga
    30301 gattgtcagt tgtcaattcc cgagattctc catctagtgt tactaatgtt tcattttctt
    30361 ttgcacggcg gacaaagatc tcttttgatt tcaatttgtc gtagtcaaat gcatgtagtg
    30421 gttgtccgaa taaaagcaaa atatagttcg tcacatctac tacattgttg attggacgaa
    30481 tgccttcgtt catcaaaaga ttttgcagcc attgaggact tggctggatt cttactcctt
    30541 caatgattct gatttgataa gcaggaactg cttctttatc ttcaacttcc acttgaattt
    30601 tatcgctagc aggacgtgag gattctacca gcttttcgtc atcgaatgta ggagtctgac
    30661 gataaattgc cccaacttca taagctacgc cacgcattga caatgcatcc gcacgattcg
    30721 gtgtgataga taattcaata atcgaatcat ccatatccaa ataaggaaaa actggatcgc
    30781 catttacagc ttcttgtggc atataataga taccttcagc gtattctttc ggtataacac
    30841 tatctgaata gccaatttct tgtaatgagc aaatcatgcc atttgatact tggccacgca
    30901 tttttccttt tttgattttt acattaccag cgatacgtga gttaggaagt gcaacaatca
    30961 ctttgattcc aaccttcaca ttaggcgctc cacaaacgat ttgagacagt tcgtcttcgc
    31021 caatatcgac ttgacaaata gaaaggtgat cagaatctgg atgtggtacg cattccttga
    31081 cttcaccgac aacgattttt ttcaagcctt cttctggaac cgttactccc tctacttcga
    31141 ttcctgtcac agacatctta tccgctaatt cttttggtgt tacattcgat aaatctacat
    31201 aacgattgag ccatttatat gaaactaaca ttttcttact cccccttgaa ctgacttaag
    31261 aaacgtaagt cattttgata gaaattacgg atatcattca ctccataccg caacatagct
    31321 acgcggtctg gtccaaggcc gaaagcaaag cctgaatatt cttctggatc gattcctgac
    31381 atcttcaaca cattcgggtg taccatgcca gctcctaaaa tttcgatcca tccagtgtat
    31441 ttacatacgt tacaaccggc accaccacat ttgaaacagc tgacatctac ttctactgat
    31501 ggttccgtaa atgggaaata acttggacgc aaacgaattt cacgatcttc cccaaacatt
    31561 tttttcatta cgacttctaa tgttccttta aggtcgccca ttgtgatgtt tttatcaaca
    31621 actagccctt caatttgatg gaactgatga ctgtgggtcg catcatctgt atctctgcgg
    31681 aagactttcc ctggcgagat cattcgtaga gcacccttag agaaatcatg tttttccatt
    31741 gtccgtgctt ggactggtga agtatgtgtc cgaatcaata tctcgtctga aatatagaaa
    31801 gtatcttgca tgtcccttgc tggatgatct tttggcagat tcatccgttc gaaattgtaa
    31861 tgatcagatt ctacttcata tccttctacg atctgatagc ccatacccac aaaaatatct
    31921 tcaatttctt ccatgatttg tgtcacgata tgacgtgtac catgttttac ttttctacca
    31981 ggtagtgtca cgtctattgt ttcttttgcc aaagctgcat ttaacgcttc ttcttctaat
    32041 acttgttttt ttcgctcgat ctcttctgtc aaaagatctc ggatctcatt tgcgaaactt
    32101 ccgacttttg gtcgctcttc tggacttaga tctttcatcc cacgtaatac ttctgtgatc
    32161 ggtccttttt ttcctaacgt ttcaacacgt atttgattta attcatttaa atcttgtgcc
    32221 gctgtgattt tgacgagcgt tgcttctttc aagctctcta attgtgcttg tagagacatg
    32281 tgcttgttcc tcctttaaat tccaaataca aaacaaaaag acctcattcc tgttaaggaa
    32341 cgaggtcttc gcgttaccat cctaatttgc ggataaatga cttacaccgc actcttactt
    32401 cgttaacgac aattgccggt ctgattttat cagacgaact cggaaagtga acttcatttt
    32461 tcaaacacag gatctgcttt cagtctgcga cagatctccc tgaactggtt tagccaaact
    32521 actctttttc gtcatcgttc tttacttatt cgtatggact atagtttaca agattttttt
    32581 tacaaaatca accgcattct tcctctgtga tccatttttc gctccaaact tgtatttgac
    32641 gcatcgcttt ttgcaagtct gctccttttt cagtcaagag atattctgaa cggctctttt
    32701 cgctacaggc aaagtttcga gtgactattc cttctttttc taattccttc aagcgttcga
    32761 ctaatactcg atcactgacc atcgggattt ttgccgcaag ctcaacaaag cgttgcggac
    32821 cgttttcgag tagtacatcg ataatcaatc cgttccattt ttttcctaaa atagagaatg
    32881 ttttttcaaa tttagggcat aaaacgaatt ctgtctgtgt tagctccatc atactcacct
    32941 cttcccagag tatagcataa tccttacaaa acataagtca agtttgctca attataatta
    33001 tttgttaatg tttataattt gtttcactcg aagcaaaatt aggaaaacat tttctactgg
    33061 cttattcaaa gcttctgaca ttgcttgttg gtaaagtctt agctgtcctt gatatttttg
    33121 gacgattgca tctatttctg ctggatcatc cggatgtaaa ataaaatctg ttttaaaatc
    33181 atagatattg agatgatctt tttcttctag gtatccatcg acgattccgt ggattaatag
    33241 ttcatcttct tgatttggat agtcttgaaa tacttcgtca gcaggaagca gcatggaaaa
    33301 aggttgttct cgttttacgt tttctttgtt ggcaatcagc tgttgaccaa gttctgtttg
    33361 aaagaaccat ataatagaag aaacatctac ttttttcgcg actttttcgt ctactaaccg
    33421 tttccttacc aattcctgta atttttgatg gatactctct gtagttggca tctctaatgg
    33481 cagtaattgt aacaaagcat gcgtagcagt tccaacagca gctgctgaca cttgccgatc
    33541 tttttgcaaa aattttggtt ctgctagttg ttcttgcgta taacgaaatt gacgggatgc
    33601 tgctttgttc tgactgcttt ccagagtcaa acgtgattct tgtgtatcat ctggatcttc
    33661 gaataatcgt ttgatttcag atacagattg ataacttgtg gtttgtgaag aagcttgata
    33721 aggatattca tatgccagac gtttttgtaa cgaatctgct aataaagttt catcttcttt
    33781 catctgctga tctaagttaa ccagttcttt ttcagcaagc aactgtcttt gttcaatgat
    33841 cgattgctga ttcatccatg aaatagaaaa ctgtgcattt gaatgttgaa gaagagaagt
    33901 cgaaatttct tcctctaagt atttctgcat ttcaggatga cggatcaatc cgtaaccaat
    33961 ccaattcatc aagctgcttc tgcccttcaa acgtagcgca ggatcaaaaa ctaactcctc
    34021 atgatcagct gcttcagacc acgtttggat catttgctct ttatttttat aggaaccgac
    34081 aatgaaaagc ttttgttctg cccgagtcaa tcctacatac aatttacgca tttcttccga
    34141 caacaatttg ttttgctttg ccaatttgat ggcttgaaac ggtaacgtat catataacac
    34201 tcgtgtttca ggatccatat agcgaattcc tgctccaagt ttttcttcaa aagcataccg
    34261 attgcgcaag tcttgtaagt tgaactcctt tgtcatatct aacaaaaata caactgggaa
    34321 ttccaagcct ttacttgcat ggatcgtcat aacgcgaaca gcattatctt ctattgaaat
    34381 gactggttct gctaagtctt tatctttttc ttgcattttt tcaatgaaac gcacgaactg
    34441 gtataatcct ctgaaagaac tttgctcgta agctttggca cgatcaacca atgcataaag
    34501 attggcttgt ctctgtgccc ctgctggcag accgaccaca tactctagat atcccgtctc
    34561 ataatagata tcccataaca agtcagtgat cgaagaacgg cgagcaagtt ctcgccaatg
    34621 ctctagttgc ttgccaaaat gttccagctt agctgctaat tcatcttcgt ttgatgcttg
    34681 ataagcaagc acagcatcat agtaagtatg tgcacggtta gctaatcgaa tgctggctaa
    34741 ttctggttca atcagaccca cgatcggtga gcgcaataca gccgcaagcg gaatatcttg
    34801 atagggatta tcgattaatt gtagcagcga gatcatcgtg cgaatttctg tcgcttgaaa
    34861 atagttttga gcatcattca tctctaatgg aatatccaat gttttgaaaa tctctaaaat
    34921 cgttaagttg ttcttctttg taggtgtcaa gagaacaatg tctttgtact ctatcggacg
    34981 actttttttt gattttttat cataaatcat aaaggaggaa tcaattaatt gacgaatttt
    35041 tagtcctgtc ataaaaagtt cgccttctgt tttgtcttcc agtatatcat ccgtcggaat
    35101 ctcaatctct gattcttcct gttctttttc atagatcatg atttccggct caaactgttc
    35161 attctctgga aagtctgaaa atccttggat cagtttggct gcttcgtcat aattgatttg
    35221 acccactgct ggatccatta gttgttcaaa aataagattc gtaaaagaaa ggacttcttt
    35281 tctagagcgg aagttctcag ccaaaacgat tcgacgtccg ccttctttct ttgagaaatt
    35341 ctcgtatttc ccgataaata aactaggatc tgctaaacgg aaagaataga tggattgttt
    35401 gacatcccca accatgaaca tatttccttt tgtatcatcg ggttctctta gccagtataa
    35461 aatggcttct tgtaattggt tcacgtcttg atattcatct accattactt ctttgaattt
    35521 ttttcgataa tgttttgaag cttcacttgg cagccataca tctttcgttt tttctgtgag
    35581 aatctgcaac gctaaatgtt ccagatcatt gaaatccagc acaccttttt cccgtttacg
    35641 catactgaaa ccgtccatga agctttgcgt gacttttgtc atttcttcga ctaacggtag
    35701 tgctttgtcc gttaattctt ccatttggct tggggaaaca ggaaaataac ttttacttat
    35761 ctgctgaatc agtttttttg ctttatccct catgcccttg acttcattgg aaatttcttt
    35821 caattctgct ttccgactgc tcttaaaagt tgaaaaagtt agttgttcca aaccagcata
    35881 agcttcttct aaccgatctt gcgagaacgc ttcatagata ttcttgatct gctgttgttc
    35941 tccagctact tgctcatgca ttttttctaa tccttcacct tgtgctaact gagtcatctg
    36001 ttcatataac tgtacacatt ggtatatatc tgccaaaact aaaggacgga tttgtttttg
    36061 atataatcga gatttcgcta gcccctcagg caaacgataa ttatcgctta actgttctag
    36121 ccatttttgg gggtcagggt tggcacgggc aaactcataa agagaaaaca ccagattcgt
    36181 caagccgtca tctgaacgat cattagaaaa attcattgtt aattggaaaa atcgttcatc
    36241 attttctgca taaagtgctt ctctcagctc gtcccacaca tcctccttca tcaagatcgt
    36301 ttctgtttca tctgttaaca tgcgaaagac tggatcaata tcaattaagt aataataacg
    36361 tcgaataact gtcaggcaaa aagcatgtaa ggttgagata ttcgctgtgg gcaataaaac
    36421 taactgctta gtaaaatgct gtctacgtac agggtcactt tcgctattga cggattcttg
    36481 taatgcctct tgaattcttt ctttcatttc tcttgcggca gcttcagtaa atgtcacaat
    36541 caataattca tcgatatcaa aacccatttt tagtttttca atcactcttc gaacaagcac
    36601 tgtagtttta cctgatccgg cagacgcaga gactaataga ttatctcctt gatcaaaaat
    36661 cgcttgccac tgatcatctg tgaatcgttc attttgcggt tttaaaggaa tttgattcac
    36721 tcttcttcac tccttttcaa tattctacgc agtgcttctt ccttatctat tttctccaga
    36781 cggtggtaat tattttcttt cagcatcaca tcaaacgtac agatgcttct gaatggacaa
    36841 aattcgcagg caatccgctg tttatcttta taagctggat ttagtttgat ttctccggaa
    36901 gtaatcgcat ctccagctaa ccgcatattt tcccgattat gcgccatgaa tagttgcagt
    36961 tcttcttccg tgaaaaattt gtctttactg aaactacctt tttggtattc atctttcgca
    37021 ttttttttca ctggatagat cagtgattgt tcttttgctt ccagtgaatg atctagtact
    37081 tctaaaagag cgggatcatc gacaaaaacg ccatcataac taaatttttt caatgtattc
    37141 ttctctacat catctgtctc cgtcaataca ggattatgaa catgtaaata atatgatcct
    37201 gctggtttaa cagccgcctt tccagtcaaa cgtaccgcat ccatcaatgc tacgtccaga
    37261 tacgtcaata attgcatagc catgccataa taagcttctg tgacatcgaa tgaacgtccg
    37321 ctagatttgt aatcaacgac gcttagccaa gtatcttctt gttcagaagc tacatcgatt
    37381 cgatcgattt tccctcgaac atggagtttt ccaccattac tcaacggtaa ttccagacct
    37441 gtgatacctt ttgctccagc aatctgacca aatagaatct ctgtctgaag aggatgcatg
    37501 cctgtatttt tgctctgttt ttgcaaagcc catgtcactt tttgaatcgt ctgtcctaac
    37561 tggtagcgga tatagttcat tcttgcagaa ctatccaata tctcaaaccg aagttctccg
    37621 aatacttcct gcagcacttt ttcagtaaag tctctacgct gcgcatcgga catattcact
    37681 aaggataatt ggtttgaaaa cagtagcttg aagaaacgat ccaatgattc atgataaaaa
    37741 tcaccagttg ctgctggagt tagaccataa acagttcgtt ctttcaattt caaaccaaat
    37801 tgcatgaagt atttgtattc acaattataa aaattctcca tacgtgaaat tgaagtataa
    37861 atctcttttc cataaagctc ttccgccatt ttttctggca tcgaaacagg aacatttaaa
    37921 tgttcctgac tttcaaaaat ctgtaaagca aaatttcgcc atgacgaatt cagtactaat
    37981 tctttgagct tttgccagtg ctttggtaca ggtttttttt catctaaagc taatcgataa
    38041 atcctattga ctgtattgat tccgcttctg taagtcccta cataacaatt agggtcgctt
    38101 tcgatcgtca aatgctcttt tctctcgacg ggaacagata aatattctgt gattctacgc
    38161 aaataaggag acatcttcag cgaaccatct gtgtcatagc tttgtgcata actaagatat
    38221 aatcgatctg ttccggaaag aaaaacaaga taggcttgga aaggctcaaa agagatactt
    38281 tcctttgatg ggtcgaataa aaactgtcca tctggcaagg cctgatttaa tacttctcgt
    38341 tcttcactgg acaacaatcc ttttgtctct tttcggtctg gaaacacttg atcattcaac
    38401 cctaatgcaa aagtgacggc agcttgattt ggtcgaacta attccaaacg attgattcgc
    38461 acttggtcga ttgcggtagg gattttacca taacttagat tttctagacc acttgtaatg
    38521 atttcttgga acagtgacca gtcaaaagcc gattcaccat aaattactac atattcatcc
    38581 aacagatcaa tcagcgctcc ccatgtctgc tcatggtttc ttgccgcttc taagtttcct
    38641 ctgtctactt cctgattacg ccaaaacaat aattgttgct gtacgccact ttggatcaaa
    38701 aattgataaa aaacatttgc ggcctcttgt cctgttttgc ttttctttat ttttttcaaa
    38761 aatactggta cagctttctg aaataatcgt ctaatcgtat ttgactgttc ttccaaatac
    38821 tgtacgtctt caatctgttc tgcttcaaaa tcatacgcca caaactgcca gtctttttca
    38881 cgagtccaat aagttccttg ataattgtaa gcaagtgcta cattttcagt gatgtccagt
    38941 tttttcctga attcatctcg ctcttgtttc cattcatcaa gttcggtttc tgcttccgtc
    39001 gacagaaata attcagtttt gaaaaaacgc ataatatcac ttagccgata agaatagcgg
    39061 tcaagagcga acagactgtt gatccattcg atcagcggat gattttccat catttgttct
    39121 tcatcgatat aaaaaggaat tgccatttct tgaaagatcg gccgaaggat atttccatat
    39181 aaagacatat tttttgtcag cacttggata tcacgataac ggtagttttc ttcactgact
    39241 agtcgtctga tttcaacagc taattgtcgg acttcttcag ttggattttc agcttcccac
    39301 aaatggagat gctcttgtcc ccctattttg tgtactgccg ctttcttttg gctagatgtc
    39361 tcttcccaca ttgtttgcag cagttgaagc tctgtcggac gagtctgctc tggtgcaaat
    39421 cggtccacta atatagggac tttccgttct cttgcacttt gaaaaagacg gaaataaagc
    39481 tttccagtct catgaaagag cgtaagtact tctggaagat ccgctgtata aggacgatcc
    39541 agcaataaat cgacaaccaa ttgccccttt tccatcattg cctgcagtaa ttgatactct
    39601 tgaccattga ttcgagaaaa accactgaca ataaatttga cgttgttgaa atcttgtgtc
    39661 tgcatataat ttgctagtat agatagtgca tcttcatttg ttagtgcacg ttgagtcaat
    39721 tcgctgtcat aagctgaaaa aatcagcttc aagtctttca ttttaagttg ctggtcttct
    39781 gcattaggtg aatcaccaaa taaaagcatc aggtcttctg gttgaatatt tcctgtacgc
    39841 aattcactgt agagttcttg taattgacga ataaaccctc ttttattgat ttctccgcga
    39901 aagattgtta attcttcctc atttttttct aaaatctgtc gcaagatcat tgcagatcct
    39961 gattctgata attcatttcc tgtaagaaga gttgtctgtt gcagcaaata ccaagccaga
    40021 cgataaaaac taaatacttg aacgtttgtt gtgctgaaag ttttttttcc gcttcttctt
    40081 cgcatctccg ctaaaatttc ttgttcctgt tcgaatttgc tgtagttggg aacaaggaaa
    40141 aatacttggt tacttgcatc ctggtcgagc caagcggatg cttcgtcgat caagacttga
    40201 cggtgatctt ttttcccgtt tccaagaata aattgtaaag acatgctttt cctccttcaa
    40261 cacatgatac ggtgctcctt tattatatca aaaaatactg aacatttgtt ctatattctt
    40321 caaattatat ccttttaagg ttctgatatt tctacttttt taagtatacg caaaaa
//
LOCUS       DAFBSV010000015        38025 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.015, whole genome shotgun sequence.
ACCESSION   DAFBSV010000015 DAFBSV010000000
VERSION     DAFBSV010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38025
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.015"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(366..1676)
                     /locus_tag="LLB18_000782"
     CDS             complement(366..1676)
                     /locus_tag="LLB18_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBK5243803.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1688..3106)
                     /locus_tag="LLB18_000783"
     CDS             complement(1688..3106)
                     /locus_tag="LLB18_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5243804.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3346..4914)
                     /locus_tag="LLB18_000784"
     CDS             complement(3346..4914)
                     /locus_tag="LLB18_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBK5243805.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNAGRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4918..5328)
                     /locus_tag="LLB18_000785"
     CDS             complement(4918..5328)
                     /locus_tag="LLB18_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HBK5243806.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5325..6248)
                     /locus_tag="LLB18_000786"
     CDS             complement(5325..6248)
                     /locus_tag="LLB18_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HBK5243807.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6245..7123)
                     /locus_tag="LLB18_000787"
     CDS             complement(6245..7123)
                     /locus_tag="LLB18_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HBK5243808.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7110..8447)
                     /locus_tag="LLB18_000788"
     CDS             complement(7110..8447)
                     /locus_tag="LLB18_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBK5243809.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8450..9553)
                     /locus_tag="LLB18_000789"
     CDS             complement(8450..9553)
                     /locus_tag="LLB18_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBK5243810.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9627..11135)
                     /locus_tag="LLB18_000790"
     CDS             complement(9627..11135)
                     /locus_tag="LLB18_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBK5243811.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11101..11793)
                     /locus_tag="LLB18_000791"
     CDS             complement(11101..11793)
                     /locus_tag="LLB18_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBK5243812.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11815..12789)
                     /locus_tag="LLB18_000792"
     CDS             complement(11815..12789)
                     /locus_tag="LLB18_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK5243813.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13089..13961
                     /locus_tag="LLB18_000793"
     CDS             13089..13961
                     /locus_tag="LLB18_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBK5243814.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14419..16617)
                     /locus_tag="LLB18_000794"
     CDS             complement(14419..16617)
                     /locus_tag="LLB18_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5243815.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16849..17841
                     /locus_tag="LLB18_000795"
     CDS             16849..17841
                     /locus_tag="LLB18_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5243816.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17901..19322
                     /locus_tag="LLB18_000796"
     CDS             17901..19322
                     /locus_tag="LLB18_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HBK5243817.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19315..20814
                     /locus_tag="LLB18_000797"
     CDS             19315..20814
                     /locus_tag="LLB18_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HBK5243818.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20853..22247
                     /gene="uxaC"
                     /locus_tag="LLB18_000798"
     CDS             20853..22247
                     /gene="uxaC"
                     /locus_tag="LLB18_000798"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBK5243819.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22406..23089
                     /locus_tag="LLB18_000799"
     CDS             22406..23089
                     /locus_tag="LLB18_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HBK5243820.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23091..23927
                     /locus_tag="LLB18_000800"
     CDS             23091..23927
                     /locus_tag="LLB18_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBK5243821.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            23938..25692
                     /locus_tag="LLB18_000801"
     CDS             23938..25692
                     /locus_tag="LLB18_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5243822.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(25968..26309)
                     /locus_tag="LLB18_000802"
     CDS             complement(25968..26309)
                     /locus_tag="LLB18_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBK5243823.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26377..28548)
                     /locus_tag="LLB18_000803"
     CDS             complement(26377..28548)
                     /locus_tag="LLB18_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBK5243824.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGATETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28717..29616
                     /locus_tag="LLB18_000804"
     CDS             28717..29616
                     /locus_tag="LLB18_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBK5243825.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            complement(29687..30544)
                     /locus_tag="LLB18_000805"
     CDS             complement(29687..30544)
                     /locus_tag="LLB18_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBK5243826.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30529..33231)
                     /locus_tag="LLB18_000806"
     CDS             complement(30529..33231)
                     /locus_tag="LLB18_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBK5243827.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33244..34533)
                     /locus_tag="LLB18_000807"
     CDS             complement(33244..34533)
                     /locus_tag="LLB18_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HBK5243828.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34683..35729
                     /locus_tag="LLB18_000808"
     CDS             34683..35729
                     /locus_tag="LLB18_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5243829.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35731..37884
                     /locus_tag="LLB18_000809"
     CDS             35731..37884
                     /locus_tag="LLB18_000809"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HBK5243830.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
BASE COUNT        11227 a         7826 c         6753 g        12219 t
ORIGIN      
        1 ttcccgattc atttttggct gccgtagcaa cttttatatc atatcagaga gacaaacgat
       61 tgtcaactct tttttaaaag tttttttcga tttcgttttt cgaaatcttt cagcaactca
      121 tttatcataa cttatcgttt gttatttgtc aagaactttt ttgaagtttt tttcgataga
      181 atcaagcttc gcaagtggtt ctttttaacg acttagttat cttatcacgt ctaaaaacat
      241 gtgtcaactc ttttttggaa ttttcataaa atgtttcaat gaagcgcgac aacgttgttt
      301 aatatatcat taaaaaaaat aaaggtcaag ctaaaatatt atttaagctt gaccttatta
      361 taatttcaac gattgtcaaa agtattgttt gcagctgtgt tgccagtttc tatagataaa
      421 tcacagcttt tgaaacataa gttttgtact gcttcgattc gcccgaattc ttttgcagtt
      481 atttggcaat gagaaaagca gacatcttct ataggctttt caggaaatgc tactaaatca
      541 aaagctcggg aaggaagtga gtaacctgga gaaaggcatg cctgtacgtt tttgatgtgt
      601 atgtctttga ctttcgtcat ttgctttgat tcaggtattt cttcagccac tgcttgccaa
      661 ctttctggca tttgagcaag gtcattgcta ttttttctat tgtattcatt atgccagtcc
      721 attatccaag aaaaaggaaa ttgtacatca atcatattca gattttctac cctgatattt
      781 tcgatcactc cccctctttc ttttgaagat ttcattcgaa taccacagtc tgactgaaaa
      841 aaatcgatat cgtgaatata tacgtcacta actccagcac taacttcgct accaatagtt
      901 acaccgtatc ctgaacggat tttacatcta gcaacctcga ttcttgatga ttttcgattg
      961 actcttgcac cattgccatc tctgccagac ttaatagcaa tacaatcatc accacaggcc
     1021 aaatcacatt catagacacg cacatttgtt gaagaatcaa tatcaatccc atctgtactt
     1081 ggtccatcat tgttgcggat gattactttt tctactaata catcgttaga ataagtgatt
     1141 tgcaagttcc aaaaacctga tttctgaaaa atcaaatcac gaacaacaac atgttctgca
     1201 tgatacagta aacaagcgcg tggacgttta atagcataat ccgcaatcca acgaagtccc
     1261 ttttgatcgt attcagctct tgtcccgctt ttttgatctt ttccccaata cagctcccac
     1321 caatggtctc cttgaccgtc gattattcct tttccttcta taagaatatc tttcgccgag
     1381 agaacattca aaatcgctgc tggccatttc atttctacgc cggctactcg tgtatcgatt
     1441 tctggaaatg cttcgatatc tgttctcccc ttgaggactg caccttcttc aaagataaga
     1501 tgactcttat cttttaaaaa aagggctccg actaaataaa tgccttttgg aataaataca
     1561 ggtaagtgtt ctttcgcacc ttgatcgatt gctttttgca gtattattgt atcatcttgt
     1621 tgagtgtcgt ttgttttaaa gttcaaagca ttgataatcc ctttttttgt ccgcaatacg
     1681 tttctcccta tctttcattg atttttttca attcttcacc aataaataca gtttttgaac
     1741 gattcagtgg gtaacctact agcaaaatga ttgcggatac aaataagcag aatgctggta
     1801 acaagtttgc catcgtataa atcctttctt gtactaaaac tgattggatg gctccacctg
     1861 ttgtagacga ttggtaacca atgagtgcca gcataaatcc gcctaccgct cctgcacatg
     1921 cttgtcctac ttttctcgca aaagaattta ctccatatac tgttccatct tctcttaagc
     1981 ctgtcttata ttgatgataa tcaatcacgt cagtaatgaa tgcccagacc atcaaattga
     2041 ataaaccaga tcctaaagta gcgataaata aaagaatcag atatacccat gcatttgtta
     2101 tatgaaggaa atacatcagc aagtacatac atgaagaagc aagtaacgca aatacgcttg
     2161 cttccttttt accaaataat tttgtcagct ttgtagcaaa tggtgctaaa actactactg
     2221 ttccgtaagt aaataaaaga gcaacagaca ttgcttgttt attatggaag taatcattga
     2281 ataaataagt catattcgtc ccagctaaaa tctgattgat cacaatgaaa atgtcaacaa
     2341 tgactaaaat aatcagtgct cgattagcta acaaaccttt taccaactga gaagcagata
     2401 ctttttcgtt tttgacaact cttactcttt cagtagtcaa tttacaagtt aacatatatg
     2461 cgacaaatgc tattgcagca catccgattg aaatccaaaa gaaatgattc cctgaaacga
     2521 cttgttgtcc actcttgtta tgggtataca ttaaaatcgg aatgaagaat cctgtagttg
     2581 atccgccaat cgcagaacca atgcttcgga acgtggacaa cgaggtgcgg tcattaggat
     2641 ttgagctaat tgctgctgcc attgctccat acgggatatt gattgttgag agaaaaatcc
     2701 cataaacaat gtatgaaaca aaaatataag caatcttcac cgtcattgga agatgttgga
     2761 cgaatggcaa aaacaaaatg acagtcacta agcaaaatgg atacttcatt tttctgatcc
     2821 aaggaataaa tcggccagtt tctgttaact ctgagacatc acataatctt ccaaccatca
     2881 catcagcaaa cgcatccaaa attctcgaaa tcaagaataa cgtacctacg attgcccctg
     2941 aaacgccaag aacattcgta taataaatca tcaagaaact attgactaaa cctaaaataa
     3001 aacagttacc tagatcaccg aacatgtagc ctatcttatc ggaaatccca aattcctttt
     3061 tttctttttt tattgtattt gctgtaacag cattttgtga aagcatttga attcctccta
     3121 cctcttctag taaacgtttt caaaattata actctttttt tcttgttttt atattcacaa
     3181 tgttggcttt ttattgcatt atcttgacag ataaaaaaca aaaaataatc taaaaacatt
     3241 gatgcataag attgataact ttttttacat aacaatatat acaaacaaaa aaattcacta
     3301 actagtgaaa ataagttagt gaacctcatt tattaaagaa ttaaattaca gatgatcttt
     3361 tccatcatac ttgaaaaact caaaatcagc ataacttcct ctttttttat ttagatcatg
     3421 cactgctatc ccgataaaat ttccagtaaa ccctcctgag agtatacaca tgtttttttg
     3481 cggacctact ttcttccatt cttcagttga tacgtctttc aaatgaaact gtgctgtctc
     3541 tttctttaca gtgactttca aaaaagtctt cttttctgtg agtggaatcg tccaatcttc
     3601 tatttgtgct actccgtttt ctgattctat catacgtagg cattttccct tgtcctcatt
     3661 ccaagtaaca taacaataaa tataattgga ttcatttaag tacagtacca gtccagccat
     3721 ctgattaaaa ttattaggca tgtattcaaa tgctgtctcc gcatcaaaag taaaatccgt
     3781 ttgccgaata gctaacaaat gatgttcgaa ggtagattga agagattcac cggaaatcag
     3841 acgtaaaaaa cctggtctac attttgtatc acaccaatca gcatttggca aaatgcgtcc
     3901 ggcattccag ttcttcttta gctctccttc aaatgtatcc ataaactgat gatctttttc
     3961 ttgttgtacc tcttcatttg tctcaatcat tatttcttcc atcggagttg tctggctatc
     4021 tttaagtctt aaccaatcgt cggacgtcca atacacttct tgaatagcgg tttctcttcc
     4081 caaaatagcc gcaccgttta atggtctggt acaaagatat gtcatgtacc atcttcctga
     4141 cggggtttgt actaagctcc catgtcctgt acattgcaat gtagaagcag gtttgtcact
     4201 agctgtcagc ataggaaaac caggatcaag ctcgtaagga ccagtaatat tctttgctcg
     4261 gcaaactgta actgaatgtc ctcttcctgt accgccttct gccgtcatca aataataata
     4321 cccgttacga aaatacaaat gtggtgcctc cgttttcgct aattctgtac ctgcaaatat
     4381 tttatagatg ggaccatcaa gcttcttctt ctctgcatca tattcttgta atacgatacc
     4441 gctggattta ttcggtgtgt ccagacgata atcccatagt tcattgacaa gccatttttt
     4501 tcccgtttca agatcatgga acaaagaagg atcaaagccg ttactattta aataaattgg
     4561 ttcggaccaa ggacctgtga tctcagatgc agtgatcaaa taattgtgga catctttaaa
     4621 cggacggcct gcacttttga catctgtgta aacaagataa aacaatccat cagcataact
     4681 gatctgtggc gcccatatac ttccatttgt aggatttcct tgcaaagata cttgagtggt
     4741 caaaatatcc gttgtatgtg accagttgac taaatttttc gactcatata ctcggattcc
     4801 tggaagccat tcaaaagagg agacaataat gtaataccgc tctttcactc ttaatatatt
     4861 aggatctgga ttgaatcctc ttaaaatagg atttttcact ttgatagtct gcatgattca
     4921 ggctcctttt ctcattctta ctcgatataa actgaatgcc ccagctgcga aataaaaaaa
     4981 tgcaaaagga aacgcaataa actgagtgcc aatcaacaat atgaatcctg ttataaaata
     5041 caaaccagtg gcagttgtta agtattttcc tttagcagtc aaaaacaatg ctactgctaa
     5101 aaaagcaagt gaaataaaca acacaacggc aaacagacca gtcatgtcct gtaataatcc
     5161 aaatgtattt tctaaagaca aagttgaatg atctacagca agcgactgat aacttttttt
     5221 aaactctgac gcagacatat tacttaaagt aactgctaac ccgccaaaga aaatcaaaga
     5281 tagactgcca ccgaccattc ctagcaatag ttcccatttt cttttcattt ctgaaccccc
     5341 tgcttttcta aatgtatcca ttcaggtctt ttgatcgatg tttcataatt gttattacgt
     5401 tcagagaatt tgacagtctg ttcatttttc ttgtcatccc aattatccca accagttggg
     5461 tgaacatgcc cacctatctt acacgcttca aataagacat ttgcatacgg acgccacggt
     5521 cttcctaaat agacgtttct agtatcaggt tctgcagtca aggtacagct ttcaaaacga
     5581 taccctgttt tttgattttt cggcgtagat gctgctgtga tgtatccagg atttttactg
     5641 gctaagctat ggatatgaca ctgatgaaaa acggcatctg ccccaccaaa tatgaaatcc
     5701 accgttcctt caatccagca atattcatag gtctgacgac aatactcagg attggcagaa
     5761 gccggtgtac aaaaaggagt accatctttt tgcaaatcag gcaacggacc cgtgcataag
     5821 gtatcctgat aaccagatag tcgacagttt tttaaagata cgcgatctcc tgaattgaat
     5881 aaagcaacag cctgtcctac cttttctcct ggacctgctg tattttcgat gtgaagattt
     5941 tctaatacga cattcgatcc ttctaagaaa aaagtagcac ttcggaaagt ccctaactgg
     6001 ctaccgtcaa gatactcctg ttttgcaaaa cgattaccgg agataactac tgttcctgct
     6061 cccacaagtt taaaattgga taatctgctt tctatatatt catcatatct tccttctttt
     6121 actatcaaga cctttggatg gctatccggc aggcctgcca aataatcgat tccttcttgg
     6181 atagtttcaa aatccgtcgg ggtatctata gcattctttc caattatcag tttgtctttc
     6241 atcctcataa atgctccctt atgaattgtt tccaaatatt tctcatttct tgtgtttcca
     6301 tatgaccgcc tgttaaagaa aaagaagaaa agttttctgg actacccatt gattgatact
     6361 ttttgtccag cccttttctc agcttcagta cgccttcgtc caagcacatc gtatcgtttt
     6421 ttccaactaa gctaagacga gggcgcggag cgattttttc ttggattgct aacgttgtat
     6481 aagctgtcaa tagatttggc acatagtaat aaaacccatg atgatctagg cggcgatgta
     6541 gcaaaagtat ttcgatgtcc acctgtgccg ctagatcaat acaaactttg acacgagaat
     6601 ccaatgctgt cacccaccag cttaataagc ctcccataga aagaccaatc gttgcgagcc
     6661 gttgagtatc tgtgtcttcc cttgtctcca aataatcgat caagctgatc acatcataaa
     6721 tacgcattcc ccataacgtt tttcctgtta ataaaaattg tttgaacaac tcgctttcag
     6781 aaatacctcc gcgttcttca aatccccaag catcaatcga ccaaacagca tatcccattc
     6841 ctgtcagtac ttctgcaaaa gatggagaag ctaagtaagg agcaccatgg atcaattcac
     6901 ttttcccgac tgaaaaatct ccgccgtgag aatgcaggta aaggaccggc ggaaacggtc
     6961 cttctttttc tggataagca tagagggctg gtactgtttc caattcattt aagtacaatt
     7021 gatagtattc aagcataaaa ccgttttgtt tttctcggta taatcgtttt ccactagggg
     7081 tatgtctgct agatggagca cctaaaaaat cattcaactg cataagcaaa gtttttacga
     7141 acaaccagtt catccatatt ttctgattga tttgattgga atttctcaat actgatttct
     7201 ttagtatttt ctaatagaaa tgctggtccc tcgtgatttt caatcgacat ctggttaaag
     7261 gaaaccttac ccgcaaagcc aatataaaat ccttgtctgc tcatttcctc tattcctgtc
     7321 atcatagcag gaacaccggg aactgcatct tgggccatcg agacatcgat attgtcaaat
     7381 gtgatttctt gtatgaattg ttccgctaat ccataaataa aacctgcaga agcatggaca
     7441 ttccttgccg tgatattcga aaaatggatc cttctgaatg ctggtgtccg ttcatctatc
     7501 ggataagcct ttttttccca tacatacggt tctttccctc gcggaccaca gaaataataa
     7561 agattcagta taaatggaca catcacatta tccatgacta tattggatac tcgaatatct
     7621 tcaacgatcc cgcctcgacc tcgtctagat ttcaatcgta ttcctcgatc agtttcttgg
     7681 aagatacaat ttgaaatggt aatattacga atactaccac tcatttcact tcctaatacg
     7741 acaccgccat gtccatggac catcgtgcaa tttgtgatcg tgatattttc gcaagcgatc
     7801 ctttcgtacg tatcttcagt ccctgccttg attgcaatac agtcatctcc cacgtcaata
     7861 tggcaattac taatacgcac atttttgcat gattctggat caattccgtc tgtatttggt
     7921 gaatccgctg ggttcaagat cgtcaagtta tcaaacgttg cattactgca aagaatcggg
     7981 ttgatcgtcc aacttggtga ctggatcaat ttaatatctt tcacagtaat tcgatgacag
     8041 ttatggaaac tcatcaattt aggacgagga taagcgagat tatctggttc atttctaaaa
     8101 gtatgccacc atttttttcc atttccatct aatgtaccga aaccagtgac agagatgttc
     8161 tctacatttt gagcatagat acaggaagca taaacttttc gatggactcc ttcccaacgt
     8221 gaatgaacaa caggataatc ttttggatcg tcagagaatt tcagaaccgc tcctgcgctt
     8281 aaatgaagtt cgacattgct ttttaaaaat aaagctcctg ttagaaattc acctgctgga
     8341 acaactacgg tcccgcctcc gtcacttgct gcagcatcaa tggcttgttg tattgcttca
     8401 gtattcaatt catcaattga tgcgccaaat gtcaaaatat catacatatt tataatgcct
     8461 ccacttcaat caatgcttgc aagaatgcac caacgccttt ttgatcatta caaataattg
     8521 gttcactgat gtagtaagca tatgaaccat ctcgctgatc tgctccgcct aaccctgcta
     8581 cttgacagtt tttattcaag ttcagccagc cttcttttgt ttccagaaca aattcatcaa
     8641 gtaatccttg atgtgatttc ttcacttgtg gaagccattc ttctttgttc agcagtccca
     8701 aacgtattcc tttagccatt gcgtaaacaa acatactact gccggaagct tccagataat
     8761 ttcctttccg ttttgtttct gttgttactt gataccatgt cccgctgttt tcttcttgat
     8821 atggaagtaa tgcagccagt gtcttttcta gaatttcttt cagcaaagaa caatctgttt
     8881 cttcatgaag taattcatag gtatctgctg cagccatcaa ataccagcca atcgatcggc
     8941 tccaaaaatg atgggataga cctgtttttg gatcagccca tggttggacc ttcttttcat
     9001 cccatgcatg aatcagcaaa tttgtttttg gatcgaatag atgtttataa ctgatttcaa
     9061 actgtctcaa aacatcttgg taatcttttt cttcactaaa attctggata aattcagcat
     9121 aaaaaggaga acccatatat aagccatcca accaaatttg ataaggataa atttctttat
     9181 gccaaaaagc tccttcggat gtgcgtggat ggtttgccaa ctgctgggaa aggagttctg
     9241 ctgctttttt atatttttct tcgcctgttt ctttgtacaa taaaaagaaa agctttcctg
     9301 tatttacatg gtcgatattg tattcttcaa cgctgtagcc acggatcgtt ccatcttctt
     9361 gcacgaaata gtcgatattg tcttttatga aatcaaaata aattttttct tgggttcgtt
     9421 cccaaagtaa ttggaaccct ttaagtacga cgccatagtc ataagaccat tttcctttat
     9481 accacttttc ttcatataag cgaggtgttc tttccatgat actttttgct aatttctttg
     9541 accagttttc cattatttgc tctcctttaa aaattaaaat aggatttggg acaaatacca
     9601 agaagtattt gtcccaatcg tctatattac tgtgccgctg ctttgtatgc ttcctcgtac
     9661 tcttgtgtga ttcgatcgcc tccttgtgct ttccagtctt ctacagcttt tttgaatcca
     9721 tcttcgtcaa gctgtcccat gatgtattgc accgtagcat caatgacgat tttttcaatt
     9781 tctgatccta cttcattgtt cgtcggtgaa tccaatggca cagaaggatc cattacagca
     9841 aattcttcat tttctttgat caattgatta gagaattctt tttcagggtc tgtatctttg
     9901 aaagagaacg tcacttcact aggacgagag cttgataacg gttgcacctc ttgttgccaa
     9961 agatccatat cgataaattc gatagaacca tcatcattca attcataatg cgttccttcg
    10021 ataccgccag tcatcaattt atacacatct tcttctaaaa gatcatcaac aaattgaagt
    10081 aatttcttca attgtgcttc gtcttttact tgagatttgg gaaatgctag caagccgcca
    10141 ataccatttc cttctgacca aacatgataa ccgccgcctt caccatctga gatcttgttt
    10201 acaggcacta attccatatc atcttgaata ccttgaccca tcgtcttcag attcttgata
    10261 tccaccattc cagtgtagat tccagttctt ccttgtgcaa attgttcttg ctgatcagtc
    10321 ttttgggtaa ctgcaaagtc ttgtgccaaa tagccattct caaatagatc tcttgaaaaa
    10381 ttcaaagctt tcatatactc ttctgtatca aattctggag tgaatttgcc attatcgtct
    10441 acagcccagc catttggtgc tccaaaataa gaagtgaaaa gtttaaagct ggtataacga
    10501 atatcactag gcgcacgatc gccaaaacca actgtgtcgt ccacaccatt tccatcagga
    10561 tcgttttctg taaattgttt agctacttca taaagctcat ccatggtagt tggaacatct
    10621 agtcctagat tatccaacca gtcttttcga atgactaagc cagcacgagc gtagtctttt
    10681 tgtatcggta cgccgtacaa ggcaccgtcg atactcgcag cttcgattct atcttcagaa
    10741 atttgactta aatttttata gtcttttaaa tattctgata catcccagaa tacgcctgat
    10801 tttaacgcat tgcggacaga agagtttttc aacatcgcaa tttgaagtgt aacgatatct
    10861 cctagttcat cagaagccaa tgcagttgtt aatctttctt cttttgaagc atcaggaatc
    10921 cagttgaatg tcagttccgt atcggttttt tcttcgatca agttcacaat cgtgtctgta
    10981 ggcggtgaag catgatgcaa aatatttaac caagtgattt tagcttttcc atcttctgtc
    11041 tctgaagaac tgttacttga actgctgccg catgcggcaa gtgctagaat tcctgcaaaa
    11101 ctaagaccta attttacgag cgttgctttt ttcataaatt ttctccttca ctgttttaat
    11161 aatatttttg ttttcttctg ttttttctgt atatgagttc ttccattcca aatggcaaaa
    11221 tatagaattt gctgtccacg tgactgcgga aaagaagaga ctgccaccga taaaggttaa
    11281 aacacctggc attgtttgga tgatcatcag ataaatccct accatactta atatcaacac
    11341 taatgagtaa tgaagatgtg agaatccgaa taaaaatgcc attttcattt tgaaaaaata
    11401 tcctttccaa tcataatgag ccatgattgg gaaaatatag agtgctgaga gcacatatat
    11461 gaacgcagca atatacaaag cgatcctaag ataccaattg tgtatgaaag aaagatccac
    11521 aagtaaaaca atcccgatgg cgccatatat ccagctcatc agcaaggttt cacgatagtt
    11581 ttctttaaaa tatgtgaagt acgttttcgt caaaggaaac gtttcttttg agcgcagcca
    11641 ttttctaatc actgcaacca tcgcatacga tgcaggaccg aaagtaaaaa ctcccaaacc
    11701 tgcgatgact aaaccgcccc acagaaaatt caaataaacc aactgtaaaa tacgatttag
    11761 ccttccgttt attttatcta atgactgcag catatctttc cctctctttc tatcttagta
    11821 aacgccgtct tctcctagct ttttggcaat cttattagct aaaattacca taaacaatcc
    11881 tacgacccct ttaaacaatc ccattgctgt actgaaactt aactgtccat tcttcaatcc
    11941 agctgtataa atataggtgt cgaaaatttc tgcaacgctt cgattcaatg aattcaataa
    12001 caagtacata tgctcgaacc ctaagtctaa tgtctgaccg atttttagaa tcagcaaggt
    12061 aatgattact ggacgaattg ccggcaatgt aacatgccat gttttgcgta agcgtcctgc
    12121 tccatccatt tctgcagctt catacaactg tgtatcgact gcagttatcg ctgaaaggta
    12181 gatgatcgta gaccagccca actctttcca gatcacttgt ccgatatata ctgtgcgtgt
    12241 ccattcaggg gatgttagaa aactgatttt ttcaaatccc attgttgcaa ggaattcatt
    12301 caatacccct ccgtcaacat tcaaaaatac ataagtaatc gaaacaatga ttacccaaga
    12361 catgaagtga gggatgtaaa tgatcgtttg aatcccgttt ttcaatcgtt tgttcgttac
    12421 ttcatttaat agtaaagaca aaatgattgg catcggaaaa aacacgaaga tatttaatcc
    12481 gaacaagatc aacgtatttc ttaataatgt aaagaatgtc ggttctgtaa acaaacgaat
    12541 gaaatgtttg aaaccgaccc aaggacttcc cattattcct aaaaatggtt gataatcttg
    12601 aaaagcaata acgagtcccc ccataggaag atacctaaaa atcaagaaat aaaggactcc
    12661 cggcagaatc atcacatata aaaatttatt cgttttgatt cctgcaatta ttttttttcg
    12721 tcttctgagc ttttcttctt ttttcgatag cgtcagttga aatggttctt gtttctttac
    12781 actttccata agcccctcct tagttttgtg aatgtttgct gcttatgact tcatgataga
    12841 taactatctg aattacgtat ataatcattt ttaccgtaag taaaaacgct tacatagcaa
    12901 tgatttttgt gctatacaaa acgataaagt gtattttttc acaaataaac tacgcatagc
    12961 aaaccttcta tttttttcta tctgacactt agcataggaa atgattatat acgtaatctt
    13021 tcaccgatga taaattgaac atatagaaac agaaacattt aatttatttt gaggaggagc
    13081 ctatctatat gaaaaagaaa gtctctatag gagaaagaag ttttacactt ttcaacaata
    13141 cgtttctaat tttgctagct ttgatctgta tcgttccttt tttaaatatc atcgctacat
    13201 cttttgcttc tacacaagaa gtcgtcgcga aaaagtttat cctttttcct actacctttt
    13261 ctttagacgc gtatcgctac attctttcta cgccgaccat ttttagagca cttgctgttt
    13321 cgattggtgt tacaggtgtc ggaacgatcg tcagtatgtg tgcaacttca ctgatggcct
    13381 acggtctttc cagaaagtat ttgtttggtc gaggtttcgt caactttctt gttgtatttt
    13441 ctatgttgtt cagcgggggg atgattccaa cgttcttagt tgttcgttct ctagggctgg
    13501 tcaattctta ctgggccatg atcctgcctg tggctgttaa tgcaatgaat atgatcatta
    13561 tgagaaactt tttccaagcc ttgccggata gtttggaaga atcagcaaaa atggatggtt
    13621 gcacagattt tggtgtattt ttcaaaatta tgctgccatt agcgttaccg tctattgcta
    13681 ctatctcgct tttttatgct gttacttact ggaacactta tatgactgct attttgtata
    13741 tcaacgattc atctaaatgg ccgatacaga ttcttttacg ccaaatcgtc attgtatcaa
    13801 gtgggatgca agcagaaagt agtgccgttg atgtgattcc accagcacaa acagttaaaa
    13861 tggctgttat cgttattgca acagtgccta tgctgattgt ttatcctttt gttcagaaat
    13921 attttgtcaa aggagcactc gtaggttctg tcaaagggtg attatgtact gaacgcaaaa
    13981 tggtagttgt gtcagaagtg gtcagcttca agaaataaga aggcatttac gaaaattgct
    14041 tcttaaattt ttgtgaaatt tcggcttatt tttcgaagaa tctactcctg gaacaccgtg
    14101 tatcagaggt tgtgaaagag acgttcagcc ttgagcgatg ataaaaactc tcacaaacat
    14161 tgcgacgagt aacccacagg agcaataaga agcgattttg aaaaatagct tcccatattt
    14221 cacaaaatta tgccttattg tcgatagcct gtctcttgaa cgccatttat tcgtaaaaaa
    14281 gaactgtgac aagacttttg tcacagttct ttttgcgtgc ttagccttga aatttaacta
    14341 tccataaata caaatactag ggttattcta acttctttta ttgcttgaat cagtccacaa
    14401 gaaaaacagc ctcttgattc acaaatattt ttttcgatat tctcccggcg taatcgattc
    14461 cttcttttta aagaaacgaa taaaattttg cggatttcga tattgcaatc tttctgcaat
    14521 ctcttttacg gagaggttag tctctttcaa ccattttttt gctacctcta aacgatgatt
    14581 ttgaacaaaa tcaccaaatt tttctcctgt ttccttttta aatacattac ttaaatagtt
    14641 agggttataa tgcaacctat cagcgatcac atctaaagac agatcacgat catattctgt
    14701 gtagacgata tgcataatat tctccgacaa atttttaaat tcatgatcag tgattgcttg
    14761 agagcattct gtgattggca gaactaattg ttctaaaaca agtttttcta gttctttggg
    14821 atgataattg ttcagtgctt ttacataaat ttgtttcatg ttatcaaagt tttttgaatc
    14881 tactcccaat aactgtccta attgaacgag ttcattgatc aagcggaccg aaactacttc
    14941 ccgactcaaa ggatttttat tttgtgcaaa caatgcatca atcaattcat gtactaaatt
    15001 cttcacttcc tgatttccag aacgaatggc ttcaaacaat cgattttgtt cttctatcgg
    15061 atatctaata agtgtttttt catgagcagc aggaacgatt tcctgataaa aaataattga
    15121 acttggacca gtatttacac gataatacag ggcttctttt gcccgatcaa ccgattgctt
    15181 gctttcattc agcgtttcga accggttact gatgcctata ctgatagtta aattcaagta
    15241 ttcttttaca cgtttttgaa tgagtcggca atactccatg acttttttgc ttgcttctgc
    15301 atcatcttta tccattcgat aaatagtggc ttgcatttct tcattcaaaa cgatcggcag
    15361 cattcgattt tcctttggca caatttccgt gatcatgttg ttgatcgcta aaagtagcaa
    15421 atcacgctcc ccaccgtgac tatcttctaa cagatcgatt tgaaccaaag ctgtataata
    15481 gcagtcattt tgagaactat aaccaaattg ctgcaaccgc tgatctagtt ctcgcctttc
    15541 tactcgattt ctaaataaac taagtacaaa tagcgtttcc agctgtggct tttgggtaac
    15601 taagtgtgca cttaacgctt ctttttctcc tatgatccga ctgactgatt gagcgaccaa
    15661 atctagttct ttcccactga atccttttga tttaagattc agacgttcct gtatttgaga
    15721 aatcggacgg gcaaatctgt ccgaaaataa gtaggaaaga agaccaatga gtcctaccag
    15781 tgttaaagac actgcaacta gcccgattct cagattgcgg atcattgcgc caattgcact
    15841 agagtcaact tctaatctgt aaatccaatt attataatct gatttcagta ctatatacgt
    15901 tttatctttt tctcttatca ctttcagctg attgtaatct agatccacgt ccgttaatac
    15961 agttggttgc tctttatttt ttactgtctg agtagtaaaa aggttgccaa cttcgttttc
    16021 aatagaaagt atgtcttctc cactttcacc aacaacttgt tctattgtat gtttctctat
    16081 cgtagcaatt cccaatgcat atttttcttt ttcaaacatt ggcaaagaaa tcaccatttc
    16141 gattcctttg tttttctttt gccaaaataa attatttttg ttatttatgt acttctgttg
    16201 atacttttca atttcctctt cggtcagttg actcaacgat ccattgatta ctccccattt
    16261 accagccaaa ctgactaaat cataattatt atcatccata acaatcgttt ctataaaatt
    16321 tagttctttc ctgatttcag aataagtgga gtaatctgta tatgtcagcg gatgcttgaa
    16381 tatgtccgag aaatttttgg tcgaaccata cgtagaaaac gaatattcaa tcgttctaat
    16441 tttccattca acgttagttt taacttgcct gagcaaattc tttttgtctg ttaaataact
    16501 cgattcgatc gattcatagg tattctggta aatgaataaa ctaaatccta tgacaagtac
    16561 ggctcctaat aaaaacatcg gtaaaaatat tttataaaat actgtacttt tcttcatttt
    16621 cttcctctcc tccttttaaa ataaaaggct ttcatttttc tgtaaaattg atactcatct
    16681 aattaaatga gcattccccg ctttcaagaa tagcataatt aaaaataaaa atccaagtaa
    16741 tttttaacgt gtgcaatctt ttcatatcaa agatctattg acttatcgta gttatcgtaa
    16801 tatgatgaat gcgttaacaa aaagtgaaaa agtaaggaaa atgatggaat ggtaacgatc
    16861 aaagatgtcg ctaaagcagc tggcgtttct catacgacag tttctcgtgc tttgaataac
    16921 agcagtttaa taaaaaatga aacaaaacaa aaaatacgac aactagctaa ggaaatgaat
    16981 tattcgccaa actatagtgc aaaaggttta gtgaatcaaa aaaaatatct aatcggacta
    17041 tttttctcaa gtttgcataa aggaacttca tcaaatttcc tagcagattc cattgcaggc
    17101 atccattcag tattagacac aaattacagt ttatctgttg aaagtatcga tgttgttgat
    17161 ttaacagaaa tcaacctgca acgctacgat ggactgatcg ttatgagtca aagtgatgat
    17221 gatcagcctt tcatcgacta tctcaaagaa aaagaatttc ctttcgttgt tgtcaatcgt
    17281 cacatcaatg atccagcggt tatcaacgtc actgccgatg atgcggccgg tgttatgcag
    17341 gcagtagatt acggtattgg atgcggacat acgaagatcg cttatattgg cggaaagaaa
    17401 aattttcgtt cgacaaaaga acgggaaaaa ggggtattga aaagtctaaa aaaagcgagc
    17461 atccctgtca atccagccta ttttttaaca ggagattaca gcttagaaag cggcctccaa
    17521 aacatggaat acctattatc actttctgac ctgcctactc tggttttttg cggcaacgac
    17581 gacatagcga ttggtgcatt gagagctgta catttagctg gcctccgtgt tccccagaac
    17641 atttctctga tcgggttcga tgattctcca gtcgtctcct atctcaatcc gccgcttacc
    17701 accgtacgta agcctttgaa agaaatgtgt caagaaggaa caaagctttt actagatttg
    17761 atcgaaggca ggacgatcga acaatctaaa attgagctct ccaccttgtt gatccttcgt
    17821 gagtcgatca attacttgta aactacaagt aattttatat aaaaatgtta acgtgtgcat
    17881 aacacagaaa ggaagtttat atgaaaaaac tgacaaaaga attagtgaaa aaaaacgaag
    17941 cacctgtaaa agttcttcag tttggtgaag gcaattttat gcgtggattt attgattggc
    18001 agattcagca gctgaataac caacaattgt ttaaaggtaa tgttgcaatc attcaacctt
    18061 tagaacaagg tcttggaaat atgatgaacc agcaagataa tttatatacg gtcattttac
    18121 aaggactcag caatggcgaa atcgttgata cttccgagat tatcaccgta gtagaacaaa
    18181 tgatcaatcc ttatgatgaa tgggatgctt atctatctct agcagaaaat gacgacttgg
    18241 cctatatcgt ctccaataca acagaggcag gaatccaatt cgtggagact gataatttaa
    18301 cagatactcc cccacagagc ctcccgggca aactgacagc ctttttatac cgacgtttca
    18361 aattaaacaa agctggcttt accatcattc cttgcgaact gattgacaga aacggcgaac
    18421 gtctaaaaga aatcatttta cgctacgcag aaaaatggga tttagaacct gcttttgttg
    18481 agtggttaga aaaagaaaat gttttctgtt gtagtttagt tgatcgcatc gtcccaggtt
    18541 atcctcgcga agatgcaggt gttttcaatc aacggcataa ctatgaagat caattgatgg
    18601 tcaaagcaga accattcatg ctttgggtga tcgaagggcc taaagaattg gagaatcaac
    18661 taccattcaa acaggctggc ttgaatgtca tcatcacaga tgatatgact ccttatcgtg
    18721 aacgtaaggt gcatttgctt aatggaccgc atacagcgat ggtccctctt gctttgttgg
    18781 cggaattgga aactgtagaa gaagtaatga aagatccttt attctccgca tatgttgatc
    18841 agttattcaa tctagaattg attcctatgc tttctttacc taaagatgaa ttagccattt
    18901 atgctgacca aatcaaagaa cgtttcttga atccttttgc ccatcacaaa ttagaagcga
    18961 tttcattaaa tagtgtttca aagttcagca cccgtctgct tccagtgttc aagaagtata
    19021 tcgaagaaca aaatcaggta ccaccgttaa tcactgtttc actagctgcg ctacttctta
    19081 tgtatcgagg cgatcaagta aagccacatg atgatgaaaa gacgataagc gaatttactg
    19141 atgcttggtc tgataatgga acagctattc ctcgattatt gcaaaacgct gcgctttggg
    19201 gagaagattt gtctcaaata ccgaatgtga cagatacagt tcaagaaata gctgcaaaga
    19261 tcgatcaaaa aggtgtccgg tcagtattac aagaaatgaa aggaacgatg gtccatgctt
    19321 gaaaccctgc aaccaacaat gaaattaaat cgacgagaca gtgtggtcgt cgcattaacc
    19381 cctattccaa aacaaacaca actgacgatt gatcagcaaa cgatcaccac tcttgaagat
    19441 atcccgcaag gtcataagat tgcattgggt gatttgaaag ctggagacaa cgtgatcaaa
    19501 tatggctatc caatcggtca tgtgacgaca gacgtaactg ccggtcaatg gctgcacact
    19561 cataatgtaa aaaccaatct ttctggtgaa ttggattatc gatatgaaaa agatgtccat
    19621 ccaagtcatt acctttttga gaaccgaaca tttcaaggtt acttgcgaaa aaatggaaaa
    19681 gtagggattc gtaatgattt gtttttagta cctaccgttg ggtgtgtgaa tggcattgct
    19741 gaactgatcg tcaaacagtt caaggaaaaa catccagatc tgggacagtt tgaccatatt
    19801 acgattttaa agcatcctta tggctgttcg cagcttggaa aagatcatca aaatactcga
    19861 gaaattttag cggacgcagt aaatcatccc aatgccggag gagttttagt atttggatta
    19921 ggttgtgaga acaatacagt tcctgaattc aaaaaaattt taggtgaata tgatgaagaa
    19981 cgagtgaaat ttctagtggc tcaagatgtt tacgatgaga tcgaacaagg tgtggctcta
    20041 ttagaagagc ttttaacagc agcggaaaat gaccagcgca tatcagtccc gctctctaag
    20101 ttgaatgtcg gtttgaaatg cggcggttct gatggtctat cgggaataac tgctaatcct
    20161 ttacttggtg cattttctga ctacttgatt gctcaaggag gcagcacgat cttaacagaa
    20221 gtgccagaaa tgtttggcgc agaacaagta ttgatggcac gagcggaaaa tgaagaagtt
    20281 tttgactcaa tcgttgactt gatcaatgac ttcaaacagt atttcttgtc ttacggggaa
    20341 ccagtttacg aaaacccatc tcctggtaat aaagcaggtg ggatcactac attagaagat
    20401 aagtctttag gctgcacgca aaaatcagga agctctcctg tcgttgatgt gctacaatat
    20461 ggcgaaaaaa tcagaaaacc agggcttagt ttattgcaag ctcccgggaa tgatcttgta
    20521 gctgcctctg ctcttgcttc atccgattgc cagttggtct tgtttaccac aggaagaggg
    20581 actccgtttg gctcatatgt cccaacggtc aaggtatcta cgaatacaac tctttttgaa
    20641 cgcaaaggtc attggatgga ttttaatgca ggcgtcttat tagaacaacc aatggaagta
    20701 atcttagaat cgtttgttca aaaaatcatc gctgtagcta gtggagaaga aacgaaaaat
    20761 gaacaaaatg acgttcgaga aattgccatt tttaaaaacg gagtaacact ttgattttca
    20821 taaaacagta taaaaagaaa gaaggaagat ttatgttttt atctgatgat tttttattaa
    20881 aagacgattg ggcgaaaaag ctttaccatt cctacgcaaa aaacatgccc attattgatt
    20941 atcactgtca cttagatcca aaagaaattt acgaaaacaa caatttcagc aatctgacag
    21001 aagcttggtt aggaggcgat cattacaaat ggcgcttgat gcgagcttgc ggcgtgcctg
    21061 aagaaaaaat cacaggaaat gcttctgatt ttgaaaaatt tttagcttgg tgtcaaaccg
    21121 taccaaaaat tatcggaaat ccgctttaca gttggtcaca tcttgaattg aagcgtttct
    21181 tcggtattga cttgttgata aatgaagaaa atgcagagaa aatttggaca caagcaaatg
    21241 aaattttggc agctcctgat tttcgccgtc gggaaatcgc aaaaaaatcg aatgtagaag
    21301 tgatttgtac aacagatgat cccgcagacg acttgcacta tcatcagttg cttgctcatg
    21361 aagaaccaga tttgaaggtt ctaccttcat tccgtccaga taaagcactc aatattgaaa
    21421 aagaaggatt taatgcatgg gtcacactac tggaagaagc agctgaccaa acgatcacca
    21481 cctatcaaga actgatagaa gtcttagggc agcggataga atacttccat caacatggat
    21541 gtcgtgtttc cgaccacgct ttagacatct tacgctataa agaagcggat gaaacagtat
    21601 tagaagagat ttttcaaaaa gcacgagcta acaaactatt atcttcagat gaaatcgatg
    21661 cttatcgtac agaaacactg atacatttga cccacttcta tcattctcat aattggacga
    21721 tgcagctgca catccatgct tatcgtaact gtaatacaca aatgttggaa aaattagggc
    21781 ccgataccgg ctatgatgga atgaatgatc tttctttgac tattcctctg caaaaattat
    21841 tgaaccgtgc agaagaaacg gatcagttgc caaagacgat cctttattca ttgaatccga
    21901 atgactatcc tgcgatttta gctttgatgg gctgtttcca aaaagaacag aatggaaaac
    21961 tgcagttagg ttctggatgg tggtacaacg atactcgagc tggtatgcgc gatcaattga
    22021 cacaatttgc tgatggtagt gctttgggga attttgtcgg catgctgaca gattcaagaa
    22081 gtttcctgtc ctacactaga catgaatatt tccgtcgtgt tctttgtgaa tttttaggcg
    22141 aaatggtcat gcgaggagaa gcacctgaag atgaacaact tttaggaagt ctagttcaag
    22201 cgattagtta tacaaatgct aaaaattact ttggcttttt tgcctaattg attaatagta
    22261 acagtaacga atcaaaaaca ggatagtgaa ataacggaat ccgtttatcc acgttttaga
    22321 gaagaagacg gaccaaattt gctccgtctt cttctcttgc tgttctgctt cattgcctat
    22381 aaacctttat gaaagaagag ataacatgcc tactatccat attgccggtg attctactgc
    22441 ggcagaaaaa gatgaaaaca agcgtcccga gacaggttgg ggagaaaaaa tctctgctta
    22501 tttttcaccc gagatccaga tcaataacca agcaaagaat ggacgcagca ccaaatcatt
    22561 tatccaggaa ggaaggttag cccgtctagc ttcacagttt cagccgaatg atttcttatt
    22621 tgtacaattt ggacataacg accagaaaat ccaagaagaa agaggtacgc ttcccttcgg
    22681 tagctattta aaaaatctgc agatattttt tgaatgcgca aaaaaagcga acgtccaaat
    22741 ggtcttactg acatctgtga cgcgacgaga ttacttagaa aacggaacat tgaatccaga
    22801 tatacttgga gactatccaa aagcgatgcg tgcatttgct gagaaacacc atattcctct
    22861 tttagatgtg ttctcaagat cacaagaatt gttccagacc ttctcaaaag aagagacaaa
    22921 aaaattctac ctgcatctta tacctgatac ttgtaaaaat tacccagaag gactaaaaga
    22981 caatacccac tttagtccag aaggcgctga taaagttgcc cgaataattg ttgaattgat
    23041 aaaagaatcc cgtctgcctc ttgctaatta tttacaaaaa ggagtttgag atgtttccat
    23101 taaatttagg catccgtgcc cacgatttag atgttcgaaa tcgtgaagaa atcgttcaaa
    23161 aagtatcaca gcttcacttg tcccatatcc aatttgcacc acaaaaagca tttcctgaac
    23221 aacttaaatt aactgacatg acacttggga gtgctgccta ttttggtgaa tacttccaaa
    23281 aaaacaatat cgaactttcc attttaggat gctatatcaa cctatccagc aaaaatcaag
    23341 aagttcgtgc acaagcattg gcaactttca aacagcaaat tgctctgtgc tctgcctatc
    23401 aagccaagat gattgctacg gaaaccggta gtgtctctgt cggttacaca aaagaaaatt
    23461 ttactgaaga agcttatcag atcgccagaa attctatcat tgaattagtc gctcatgcag
    23521 aaaattttgg cgtaactgtt gctgttgaag cagggatcaa tcatccaatc tataactatc
    23581 agttagctaa acgtttaatc gatgaagtag cttcaccaaa tttaaaaatc attttagatt
    23641 gtgcgaattt gatgcataaa gaaaatcatg ctgatcagga aaaagtgatc cgaggtgcct
    23701 tggacaattt acatggttat attacagcgc ttcatctcaa agactatatc atggaaaatg
    23761 gaaagatccg catggtacct gttggcaagg gctgtttaga tttccgcccg gtactgcatt
    23821 atatcaaata tgagcgtcct ctaatgtacg ccactcttga agctactcct gagatttatg
    23881 ttcctgaagc aatagaacac ttgcagttta tttaccaaga ttgttaagga gaagattatg
    23941 gaggaacgaa tacagaaaag ttatcaaaaa tatcatgcaa atgcttttca gacattgctg
    24001 catctttatc agggaaatta ttggcgtttt gccatgtcag gactcttttt tattatcaaa
    24061 catcttccat cttggttaat gccgatcgct attgccaatg taatcaatgc agcttcatcg
    24121 aaagattctt ctcagttgca ggccatttat ttcaacgctt ttttgatggc ttgtctgatt
    24181 ggtcaaaata tattgacgaa ttattttcat gtaaaatacc atagcacttc gatccgtcaa
    24241 gtagaagctg gactaagagc gacccttatc aagaaaatcc aagaactatc tattccttat
    24301 caaaaagaat tgcaatctgg acgaatccag tcaaagatca tccgtgatgt agaagctatc
    24361 caaacgttgt cctctcaagt atttgtcagc ggattaaata tcgctgtcaa tttattcgta
    24421 gctttaggta tcacgcttta taaaagtcct gttgttttca tgtttttctt attgactgtt
    24481 cctctcgccg cattcgttac tctctttttc cgtaaaagga tcagacagtc caactcagac
    24541 ttcaggcaag aaatggaaga gacttctgca aaagtgatcg aagtgatcga attagcaccg
    24601 attgctcgag ctcatgggtt agaaaaacac gaaacaactc gcttaaataa gcattttact
    24661 caaatctatg aaaaaggatt ccacttagat atcctgcaat ctgttttcgg atcagtcagc
    24721 tgggctagtt ttcagatatt tcagctgatt tgtttgattt tcactgggat attagcttta
    24781 caagggcgca tccaacccgg cgatgtcgtg atgtatcaga cgtatttcac gacgatcgtc
    24841 aattccgttt ctggaatgat cacgctgatt cctacgattt caaaaggcat ggaatctatc
    24901 acttctattg gcgaactgtt gattgctggc gatgtagaaa cttatcacgg taagaaaaaa
    24961 atccaacatt tggatggaaa ttttcgtttt gaggatgttt cttttcttta tccggactca
    25021 ctcaaaccga ttatcgatca tttttctcta gaggtgaaag ctggagaaac aattgctttt
    25081 gttgggccat ctggctctgg aaaatctaca ctccttaact tattgattgg atttatccag
    25141 ccgacttcag gaaaaatttt tctagatgat cagcctttgg atgaactgga tatgcgaagt
    25201 gtgcgaaatt atttagccgt tgttcctcaa accactttgt tgttctccgc ttcgatcaaa
    25261 gagaacatca cttatggctt gaaaaacgta tcaaaagaac gtttagatga agtcatcgaa
    25321 gctgcgcaac tttcttcact gattgaccag cttcctgatg gtctggatac cttagtaggc
    25381 gaacatggca acaagctgtc tggtggccaa aagcaacgta tctccattgc acgagcgttg
    25441 atacgtcagc caaaaatcat tttgctagat gaagcaacct cagctttaga taaccagtca
    25501 gagaaaaaaa tccagcaagc cctgaattac ctgacagaaa cacccactac ttttattgtg
    25561 gctcatcggc tttcaacgat caaagaggca gataaaatcg ttgtgatcga tgaaggaaaa
    25621 atcgttgaaa taggtactta cgaaaaactg ttagctcaaa aaggctattt ctaccgcttg
    25681 aaaaatgaat gacaaaaaat aggagctatg acaagacttt tgtcgtagct cctatttctg
    25741 aataaacggt gttctcctgc caactcctcg gtcacaagtc acaatagtca tcaaacatga
    25801 gaagctgttt tttgaaattg ttccttgtaa ctcagagtta aacggtaggc tcacgacctc
    25861 ttggtaaatg gtgttcaaga gacagcctat cggcaataag aagcaatttt gtcatcgctc
    25921 aaggccgaac gtctctttca caccctctgt tgtttcataa aatagtttta ttcgctgtaa
    25981 aggtcgcgaa ctggtgtcat gatgatacgg ttcaagtcat tgatgattgt actgaagcct
    26041 tgctcttttt gcatcaagtc attgattact tcttctgatt ggattttcac agccatttct
    26101 tgtgctttca ttgcatcttc gtcgctgaac tcttgtccac tcatttgttt ttcttgtaat
    26161 tcgatttgca tcgcttggaa gtctttgaac agtttgtgtg cttcttcgtt tgcttgtact
    26221 ttctcgtacg cttctttcaa cgctttgaat tctggtaatt cacggatctc acgttcgatt
    26281 tgattcgcgc tatcgtagat gtttgacatg ttatgccctc ttttctttta gtagttactc
    26341 tctattgtaa catggggtta ttcgttttca aaggggctac tctccttgat atttccgcca
    26401 gaggtcttta gccgcttcac caattccctg aacgccttct ttcaccatat cgccgaagtt
    26461 tttcagccct tcttttgctt gttcaccata ttgattcaag ttatcttgcc aatttccaga
    26521 ctctccatta gaatttcctg tgtttccaac ttgatctgca gctaccactt gtcctcctgt
    26581 ggcataggca tctgctacac taaatcctgt ttttgaagta tacggaagga tgccttctgc
    26641 cgctgatttg aagactttcc cgacaacatt tccacttgtc ccttccaaat agtgcagctt
    26701 gctggattct tcgtaaccca tccatgtcga aatcactacg tctggcgtgt aaccgatcat
    26761 ccattggtca tttgcttttg tggcatcgaa attagtttct gtggctcctg ttttccctgc
    26821 tatcgtataa cctgcaggat tcgcagcagc cgctgttcca tttgaaaatg taccaagaag
    26881 catgctggtc atttcatcgg ctgtttcctt tgatatgacc tgttttggtt ttttgtttgt
    26941 gttatcgacg atcaccgctc cagtcgaatc aacgattttc gtgataagat gcggcgtata
    27001 catctgacca tcattggcaa atgcactgta agcacccgcc atgatcaatg gagatactcc
    27061 tttttccagt ccaccaaggg ctaagccata atacttatca gattttgcta aaggcaggcc
    27121 gaattcttct gctttatcat atcctttttg taaaccgatc tcatgcaaaa gccatacagt
    27181 aggcaaattc aaactttgtg caacagcttg atacatcggt acttctcctt ggtatgtccc
    27241 gtcaaaatta tgcgcatcgt aataactttg cggttcgtct ttcaagatac tggaaggctt
    27301 gtatccagct tccagtgctg gtgtatatac gcttaatggt ttgatcgttg atcctggtga
    27361 acgacgcatc tgtgtagcaa agctgaatcc tctaaagaca tgatctcctc ttcgtcctac
    27421 tagtgcttgt acaccacctg tattcggatc taaagctact gaagcagatt ggaccatggc
    27481 accatctgaa gcatttgctg ggaataatgc actgttttga taagtagctt ctaattgctt
    27541 ttgataatcc tgatctaaag ctgtatagat tttatagcct ttattcatga catcttcttc
    27601 atcaagacca tactcgttaa ctgcttcatc gatcactgca tcaaaataat aaggataacg
    27661 ataaccagaa tctgaattat cgtatgtgtc attaagatac gcgctgatat ctgtctggct
    27721 ttctgcttgt tcttgttctt ttgtgatttt tccgttttct tccattacac ttagtactgt
    27781 gtttttccga tcattcgcat tttttgggtg atcgatcgga ttataaatac caggaccttt
    27841 cagcattcct gccaaagtag cagcctcaga cagcgtaaca ttcgttgcat ctactccaaa
    27901 atactttctg gaagcgtctt ggacacccca taccccgttg ccaaaatagg cattgttaag
    27961 atacatggtc aagatttctt ctttgctgta cttcttttcg atctcgattg ccaaaaataa
    28021 ttccttcgct tttcgatcaa acgtttggtc taatgtcaga tacgcatttt tggcaagctg
    28081 ctgagtgatc gtacttcctc cgccccctga tgttccgcca gacaagacca ttcggactgc
    28141 tgcacgggca atccctttga tatcaaaccc gtgatgctcg taaaaattcc tatcttctgt
    28201 cgagattact gcatcttgga tatagggaga aatcgcgttt aattctacat atgttccttt
    28261 ttgggcgtac agtgtgccag cttcttcgtt tttcttatca taaatgactg tcgattggct
    28321 taatcctgat tttaacgttt cgacatttgc ttgttttgct aaaataaaga ggtagatact
    28381 tgtcactaag acacagatca aaccaatcag caaaatcaat ttgttcacat gatatttttt
    28441 ccagatgcgc tttcgccatc gatggaattg tccgagatat ggtctgatcc aacgccaaaa
    28501 actgatcaaa gcagctttta tcttttctaa aatgctttga aaatccattt gcttcttctc
    28561 ctgtctattt gattcaatcg tcttatttta ccatagtgaa agagtgtttt cttcctgctt
    28621 aagttgtagt tcaatatgtt tttttacgtt agtgcaagta gagtaacata agaatgaaca
    28681 gaaaaatgta agttttttct taaatatgtt ttaaaaatgg tacaattagt ctgcgattgc
    28741 actgaaagga gtacacttgt gaaaatcacg atcactttac ctatgaacca tcctgaaaca
    28801 acaattcgcg acttgcttga aaaggaatgg ttagttccta gaaaggttcg acactttttg
    28861 cgtatacgta aaaacgtttg gatcaatcaa caacctgctt tgttccatca tgaagtaaag
    28921 ggcaatgacc agatcacatt gttattcgaa gaaacagatt ataattatca agaagttcaa
    28981 ttaggagatg cgaagcacat ccgtgtttta tatgaagatg agcatttgat tatagtggat
    29041 aagcctgcag gaatgaagac tcatccaaat gaaccgacag aaaacagtac cttactcaat
    29101 catttagctg cttatctcga cactaaacag caacgacctt acgttgtcca ccgcttggac
    29161 aaagaaacaa gcggtgccgt tttatttgca aaaaatccat ttgtcttgcc gatacttgga
    29221 agaatgttgg aacaaaaaat gatctatcgg agatatcaag ccatcgtatg gggagaaatt
    29281 gccaaagata tgaccatcac caataaaatt ggacgagatc gccatgatcg gagaaaaagg
    29341 gtcgtagatg ataaaaatgg tcagagcgcc ttgacacatg tcactgtcaa caaagtactt
    29401 tctgaacaaa cacaagtcta ttgtgttttg gaaaccggac gtacacacca gatcagagtt
    29461 catttagctc ataagggaca tccgatcgtt ggagaccctc tctaccaaaa tagaacagct
    29521 gaacgactga tgctccatgc attagaactg cacatgatcc atccatttac tcaagaaaaa
    29581 atagtcggta aagctttacc tggattatgg gaatagaaat aaaaaagaac agagtcttat
    29641 cagcagataa tgataagact ctgttctttt tgtgtaattt gtctgcttac ttttgatgtt
    29701 cgtgttctgc taacagcaaa ctaccgataa tcccactttc attcggcagt ccccaacgaa
    29761 cgatatattc acttacttga ggtgtttcca tataaccacc catcaattca acaaattgct
    29821 gacggatttt ttgaaggaga tgatcctgat tcattacccc accgcctaaa ataatctttt
    29881 caggtgctaa cgtcaacgta tagttgatca gtgcttgagc aatataataa gcctgaatag
    29941 cccaaacagg atgatcttgc ggcagatctt gccctttgat ccctgtgcgt gcctcaatag
    30001 acggtcctgc tgctaatcct tctaaacaat ctttatgata aggacaagta ccttcataat
    30061 ggtcatctgg atggcgtttc acccaaatat gtcccatttc aggatgtgcg atccctgaaa
    30121 aaatttcttc attgatcacg acacctgcac cgattcctgt tcccacggta aggtaaatac
    30181 aactattttt tccttgtgct gctccttgct tcaattcccc atatgcagca gcattgacat
    30241 ccgttgtcca agcagcagga atattgtagc gttccttgat tgtgccaaga aaatcgaatt
    30301 gtgcccaccc ttttttggga gttgccaaaa cgtatccgta attatctttt gttttgtcga
    30361 taccaatcgg gccgaatgag ccaatcccga ttcccttcaa ttcataacga tcaaaaaatt
    30421 caaatacctg atccaatgtt tcttctggtg ttgtggtagg gatacttaat ttttctaaaa
    30481 tttctccacc atctgaaacc gcacacacaa attttgttcc gcctgcttct attccgccat
    30541 acattcgttt tcctcctcga atccgattgt ccgaatctca taaggttgga ttattgggac
    30601 aaccgcttgc ttcgttggtt cttcaagcag attcaatatg acagtttttc cattgtcttt
    30661 agttatttcc aatttttcta aatgactaga catattgaaa cctcttacta ctactttatc
    30721 actaaacttg ctgcgtttca aagctgtaat tgcaaacgtt tcacttttta tcgttaaata
    30781 ttgttgtttt gaaatcaatg ttccttcatg atgtttgatt tgttgagtgg aaaaaggaat
    30841 ctgtgctgcg tatgcatgca aataagtaga gaatttttct tctggtccat gtagttcaat
    30901 gctgtaattg aaccgatgct cacctagaca ctgtgcttct ggtgttggaa aatatcccca
    30961 atcgcctagt tctcccacac tgcgaagtag cgtcactgcg atttgtccgt cttctgttac
    31021 ttcatattca ttcaaaccaa agtttccgac tgttacaccg tactcttcat catgaatatt
    31081 gacaaatgct tgctgatgtt gcggattcgt ggggttttcc caacttttag acacatggtt
    31141 tgggcgcttc accacttcaa aaatactatc tgcttcgtga tgttccacat gtaactttgt
    31201 aggaaacaag acacgtaagc gatgatcttt catctgattg tcgagagtcg tttcaaagtc
    31261 gattttttta ctatcttttc tgattgtcat gattgttttt atttgaagga ttcgtttttc
    31321 tttggatcgt tctgcttttc gataacgaaa ttccacaacc atctgctgtt ctttttctaa
    31381 acgctcgtct gcagaaacag ggatttccat ttcctgtaga atacttattt ttgctatttc
    31441 cggtgtatct actaatactt ttacttcaga gttttctttg ttactggata ggattggctg
    31501 atcacagaaa ggttgtttaa agatatactc atttcctata tcgccgatat cttcaaaaat
    31561 atgcagatta ttcaactttc gtttgttttt gcgatcttcc attgtaatgg taccattttt
    31621 ttcaatcgtc aaatgtagag ggccgttttc gatgattcgt ccactctgat gaatcattgt
    31681 ttccttttct tctgctttcg cttccccttc tacaagcgcg aatgtttccc aagaaaatgc
    31741 tggcatgttt tctaatggta aagtcacttt gatcattctt gccatatatg gcacacggaa
    31801 acggtctttc ggcaaatcat aaccaaattg gacagtttct tcagataaaa tagctggtat
    31861 agtggcccca ctttttgttt ctacatgata cttacgttta ggcaaatttt ctaactcttg
    31921 atatagttgt tcaggtattc cttcagcgaa tctttttctt tctaattcga tggttatttc
    31981 tgcttcacca gttttatcca ttcctgcagt atttacaatg acaaatggaa agctgtcttt
    32041 tgggaatccg gtcgtatcga ttgctgcggt cagctgttct aaggaatctt gtgcaagata
    32101 ctttccaact tcatctgctt tttcaaaacg aggtatcatt tcccgatgga cagaatcgac
    32161 tgaacaaccg caaatactgt cgtgaggatg attttgcatt aatgtcttcc aagcataatc
    32221 taattgatca tggggatagt ttccactaac ttcataagcc atcgtcgcaa gtggttctgt
    32281 aatattttct agctgtcgct ggaccttggt attccattgt tttaagtaaa cccgagcaga
    32341 tgctgtattg gctaaagtat accagccatc cgtttcttga cttgtcaatt ctccttctac
    32401 tgagcctaag tcttctggca catctttttg aactgcttcc agatagtcag taaaattaga
    32461 atgaataaac tcgtaatctg gaaacagttc atttgcgaga tggattgctt ttgatatatc
    32521 tttttgtacc ggttgatgat caacaccatt catcatcaat aagtggttcg tagaggcata
    32581 ttgttctgca tccgctaatt tttgcttcca aaaggcaaga gctgcttctt tttctactgg
    32641 aatctcattc ccgttgctat accaattggc aaatagcaga ccaaagattg ctgtttgatc
    32701 aggtcctttc caccacatct ctgagtattg ggaagaatag ttttctgctt ccaaaacttg
    32761 attatcaaag ccaattggtt ttacaccacg gccaaacgct gctgctgaaa taccagcttg
    32821 tttcattaat tgaggcgtct gtcccatatt tccaaatgta tcgggaaaat agcctaacat
    32881 gacaggggtt ccccatttac ggctttcttc catgccaatc agcatatttc tcacgttcga
    32941 ttccgagctg ataagaaaat catcttgcaa gatataaaat ggtccaattc tcaattttcc
    33001 ttcattgatt gcttgttgga ttgcctgtct tttttctggc cttacttgaa gatagtcatc
    33061 taaaataatc gtttgcccat ccaaatgaaa actgttgaag gacggatcaa cttcaaatag
    33121 ctctagtaga tcgtctatca attcaatcag tcgcatgtga tgctgttcgt aagccatgta
    33181 ccattcacga tcccagtggc tatgagaaat gatatatact ttctttttca tttacgatac
    33241 ctcctacttt tctactctaa tatcaaagta atccatgact aattcgcaaa acatcatatt
    33301 tgcccaagaa aaccattctc tcgtataatt ttcaggattg ttcacatcga atccttcgtg
    33361 cataaggtgt gttcctgcgt cagttgctac aagtaaattc aatatccgct ctttttcaga
    33421 tttgtctgac gttgtcattc cttccatagc taatgcaatc ggccaaacgt atttttctgg
    33481 cgtatgggag gatccaattc cttttgcgta ctttccttca tagaaatatg gattttcttt
    33541 actcaacaat gttcttcttg tttgcagata atcttcctct tgttcagaac aatatcccaa
    33601 gtaaggtgcg gcgatcagat tgggcacatt actgtcatcc atgactgtgg cgtttcccat
    33661 tccatctact tcatatgcat aaatcgtttg ccctttttga ttaaccgttc gtccgtgatt
    33721 ctgaatcccc tcttggatct ctttcttcaa tttctgtgtt tgctgtacaa tttctttatc
    33781 atcgagtatc gtttgaaaaa tttcttccac ataacctaac acgaccaccg caaacatatt
    33841 ggatggtacc agatatccat aacggcaagt atcatcgcta ggacggaaac cagaccatgt
    33901 cattcctgta aaagctgttt ttgcacctcg cccgtcattg atcagcgtat cttcttttct
    33961 tgtcgtgtct cgtacaaatg tataaggaga gtgttcatga tcttgctctg ttttgaacac
    34021 gtccaagatt tttttgatac cttcaataaa agattgattg aattgatcag tttttcctgt
    34081 atttttgtaa agaagatagg ccaactgtat tgggtagcat aaagaatcaa tttcatattt
    34141 tctttcccag atccaatcgt tcatttttgt atgatctgtt tggtggccag caccgttagc
    34201 ttcttcgttg aaggcattcg catatggatc gatattgata taaaaaaatt gctttttgac
    34261 taacccgctg atcatgtcag ctaattcctc atcttctttt gcaatcacta aataaggacg
    34321 aacttgtgca gtagagtctc ttaaccacat cgctggaatg tctcccgtca ataaaaaggt
    34381 ggttccgtca ttttgctttt tgactgttgt caacagagta ttggcaaatg ctgctgtaaa
    34441 attctttgcc cagtccgcat ggatatcccc acatttttgt gtgatatctt ccataaattt
    34501 ctgcaccgat tttggtatat ctttataagc cactaataaa accttctttc tatttgatat
    34561 atctttaaag attatacttc atacagccaa ttatgtctac gctttcaaaa aatatctttt
    34621 tatttacttt ttcatccatt atggtattat ttgaatatga tatatcatta agaggtgttt
    34681 atatgaatca accattgtac cagacaatat ttaatgattt gcaaacggct attttaactg
    34741 gtgaattacc tgtagacagc caactaccaa ctgaaaaaga actttcacgt acctataaag
    34801 taagcagaat cacttccaaa cgtgcattga ctgaattaga gcaattagga cttatttatc
    34861 gcgttcgcgg gaaaggcagt ttcgttaaat ccgcttctcc ggaacagatt cttgcttctc
    34921 ctacaaaaac acgacggatt ctgtttcttc ttccatatgt cgctgatttg tctgttggtg
    34981 attttagcaa gggattgaac cctgtgatgc aagataaaca gattgatgtc atgatgacga
    35041 cgcttgactt tctacaaaat aaaacagcaa aagagctaat caatgaattt gacggattga
    35101 tttattatgc tcttgataca gaacaacatc ttgacttact ttttgagctt tcattgaaag
    35161 aattccctgt cgtcatatta gataaaaaaa tctatgagtt accttttcct accgttcttt
    35221 ccgataattt ccaaggcggt gcgcttgctg cctcttattt gatcgaacag ggacattcaa
    35281 aaatcgctta tttgtttggt acgcagactc atccacaatc cgttcgacag cgttaccttg
    35341 gttaccttga agcattggac aaagctggtt tgactttcca cacttcactg gatgacaaaa
    35401 gcgcgacatt agatgaattg ctttcttata tcactaagta tgaagtaact gcttttgttt
    35461 gtgaaaacga tgttgtcgct atccagacca tgaatctctt gagacagcat ggttatcata
    35521 tccctgaaga tttttcaatt atcggatttg atgatatcca agcagcagct cttgttgacc
    35581 cgccactgac aaccatcgca caagattttg aacagttagg taagcttgcg ggagatgctt
    35641 tggtcacttg gttagagaca aaagatcgac catccgatag taaatttcca gtttcattca
    35701 tcaaaagaca atcaacaaag gagaaataaa atgaatatcg gtcaaataga tactagacat
    35761 gcaacagcga atcagccaaa tttctctaat gggaactgcc agccttatac tggcgttcct
    35821 tttgggatga attattttgc accgcaaact acggatcaaa acggcagctg gtggtttcat
    35881 cctgatgacc gcgtttttca aggctaccgt cttacccatc aaccaagtcc ttggatgggt
    35941 gatttcagtc atatgctgtt tacgccgatc aatggaaaac tacaggagaa cacccttttc
    36001 catgctcaaa gttcttaccg cccagaagaa agtatatttt gcccgactca tctgtcgatc
    36061 tgtcaattac gttatggcat ctgttctaca ttgataccta gcatgtatgg cggaatctta
    36121 tctattgatt acagcaaaaa tgacagcggt ttacttttat cctttccggg acgccatcag
    36181 ctctttgtta tagatcctta cacagtggaa ggaaaaatca cacattttgc tggttcagaa
    36241 gatcctgatt tttcttttta ttttatattg agatttgaat atcctttaac aattgatgag
    36301 ttagctgttt ccaacaaaaa tagcgactcg atcccgttgt attttgaaca gacaaaaaaa
    36361 caaactatcc gatttgggac atcttttatc agctcggaac aagcagctta taacctggaa
    36421 ctagaacaaa accaaagcaa agagacttac cttgctcaca gtcaagaaca atggcagtcc
    36481 tattttgatc gtatacagct cacacaccat gatcaacaac aattgcggac gttttatcat
    36541 aatttatatc gggtgttttt atttccacaa acattttatg aaattgatcc tagtgggcaa
    36601 aaaatccact atgatacgac tagtcgatct ataaaacctg gtgttctcta tacaaataat
    36661 gggttttggg atacgtataa aacggtttat cctctttatt ctttgattgc tgtagaaaaa
    36721 tacgaagaaa tgctggaagg ttttttgaac agctatagag aaagtggcta tttgccaaaa
    36781 tggctgtctc ctgatgaacg tggacttatg cctgggacat tgatcgatgc ggtcattgca
    36841 gatgctgctg taaaagatat ccgacgagac ttgatgcctg aatttctaac ggcaatggaa
    36901 aaaggtgcta cggttcaaag caaacatcca aattatggac gccaaggaac agaagattac
    36961 ttgacatatg gctatgttcc taatcactac cacgaatcag tcaatcacac attagactat
    37021 gcttatagcg atttttgtat tagccaagtt gccaaggtac tagaagaaga ggaaatgacg
    37081 aagaaatatc agcagcaatc attgaactat caaaatatct ttgactatga gtcaggattt
    37141 atgcgttcaa aagataaaga tggcaagttc agagaaccat tttcagctaa tcgttgggga
    37201 caagattatg cagaaggaag tgcttggcaa agcagctttg ctgtttatca cgatttttca
    37261 ggactgatcg gaaaatatgg tggcagtgag agatataaag aaaaactcat tgagctgtgc
    37321 aatcagcccc caacgtttga cccaggagga tatggttttg agatccacga aatgagtgag
    37381 atggccgcga tagaatttgg acaattagct atttcaaacc agccaagttt tcactatcct
    37441 tacttgttca gttatatagg acaacctgaa atggcacagc cactgcttaa acagttgatg
    37501 actcagacct tcgacgattc tccaatgggt taccctggag atgaggacaa tggaagtatg
    37561 gccgcttggt atatcttcaa tagtctggga ttttatcctg tcacgcctgg aaccggtgaa
    37621 tatgttatcg gtatgccatt aattgacaag gctgttttgc ttttgtcaaa tggaaaggaa
    37681 ttgacgattg aagcaacgcc taatcggccg cagcaacaat ttatccataa aatcaaacgg
    37741 atggacaaag aatatacgaa attatatttt acccatcaag atttgctgaa aggcggcacg
    37801 atctcttacc aattagggat catccctcac cctaagaaat atcaagcaaa agatttgcct
    37861 ttttccttat caaactataa ttaacaagag gttgtgaaaa agctgtcctg catcaagtaa
    37921 taagaacagc caagcaaaaa tagatcctca tatttttcgt ttggttggtc ttattaccgc
    37981 agatgcaagc ttttgaacac cgtttattga gaggttgtga aatca
//
LOCUS       DAFBSV010000016        37120 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.016, whole genome shotgun sequence.
ACCESSION   DAFBSV010000016 DAFBSV010000000
VERSION     DAFBSV010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37120
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.016"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(98..1228)
                     /locus_tag="LLB18_000810"
     CDS             complement(98..1228)
                     /locus_tag="LLB18_000810"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HBK5243831.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1288..1515)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1877..3079)
                     /locus_tag="LLB18_000811"
     CDS             complement(1877..3079)
                     /locus_tag="LLB18_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBK5243832.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3139..3342)
                     /locus_tag="LLB18_000812"
     CDS             complement(3139..3342)
                     /locus_tag="LLB18_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HBK5243833.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEQLFHIQVAE"
     gene            complement(3484..4716)
                     /locus_tag="LLB18_000813"
                     /pseudo
     CDS             complement(3484..4716)
                     /locus_tag="LLB18_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4879..5691
                     /locus_tag="LLB18_000814"
     CDS             4879..5691
                     /locus_tag="LLB18_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5243834.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6715..6867)
                     /locus_tag="LLB18_000815"
     CDS             complement(6715..6867)
                     /locus_tag="LLB18_000815"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBK5243835.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
     gene            complement(7058..7936)
                     /locus_tag="LLB18_000816"
     CDS             complement(7058..7936)
                     /locus_tag="LLB18_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBK5243836.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7975..9093)
                     /locus_tag="LLB18_000817"
     CDS             complement(7975..9093)
                     /locus_tag="LLB18_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBK5243837.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9090..11189)
                     /locus_tag="LLB18_000818"
     CDS             complement(9090..11189)
                     /locus_tag="LLB18_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HBK5243838.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11240..12061)
                     /locus_tag="LLB18_000819"
     CDS             complement(11240..12061)
                     /locus_tag="LLB18_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBK5243839.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12058..12867)
                     /locus_tag="LLB18_000820"
     CDS             complement(12058..12867)
                     /locus_tag="LLB18_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK5243840.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12888..13382)
                     /locus_tag="LLB18_000821"
     CDS             complement(12888..13382)
                     /locus_tag="LLB18_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5243841.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13394..13882)
                     /locus_tag="LLB18_000822"
     CDS             complement(13394..13882)
                     /locus_tag="LLB18_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK5243842.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(13959..16655)
                     /locus_tag="LLB18_000823"
     CDS             complement(13959..16655)
                     /locus_tag="LLB18_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK5243843.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17083..18156)
                     /locus_tag="LLB18_000824"
     CDS             complement(17083..18156)
                     /locus_tag="LLB18_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK5243844.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18153..18980)
                     /locus_tag="LLB18_000825"
     CDS             complement(18153..18980)
                     /locus_tag="LLB18_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5243845.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18981..19787)
                     /locus_tag="LLB18_000826"
     CDS             complement(18981..19787)
                     /locus_tag="LLB18_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5243846.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19799..20884)
                     /locus_tag="LLB18_000827"
     CDS             complement(19799..20884)
                     /locus_tag="LLB18_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5243847.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20901..21443)
                     /locus_tag="LLB18_000828"
     CDS             complement(20901..21443)
                     /locus_tag="LLB18_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5243848.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21701..22690
                     /locus_tag="LLB18_000829"
     CDS             21701..22690
                     /locus_tag="LLB18_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBK5243849.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22687..23424
                     /locus_tag="LLB18_000830"
     CDS             22687..23424
                     /locus_tag="LLB18_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HBK5243850.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23421..23972
                     /gene="coaC"
                     /locus_tag="LLB18_000831"
     CDS             23421..23972
                     /gene="coaC"
                     /locus_tag="LLB18_000831"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HBK5243851.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23988..24620
                     /locus_tag="LLB18_000832"
     CDS             23988..24620
                     /locus_tag="LLB18_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBK5243852.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24705..25352
                     /locus_tag="LLB18_000833"
     CDS             24705..25352
                     /locus_tag="LLB18_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBK5243853.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25357..26340
                     /locus_tag="LLB18_000834"
                     /pseudo
     CDS             25357..26340
                     /locus_tag="LLB18_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
     gene            complement(26743..28257)
                     /locus_tag="LLB18_000835"
     CDS             complement(26743..28257)
                     /locus_tag="LLB18_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HBK5243854.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28395..29201
                     /locus_tag="LLB18_000836"
     CDS             28395..29201
                     /locus_tag="LLB18_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243855.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29376..29945)
                     /locus_tag="LLB18_000837"
     CDS             complement(29376..29945)
                     /locus_tag="LLB18_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5243856.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30028..32085)
                     /locus_tag="LLB18_000838"
     CDS             complement(30028..32085)
                     /locus_tag="LLB18_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HBK5243857.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRDQTAIKGKDLHLRTGESYAPKDLVEYVTK
                     SDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTVI
                     THFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDWM
                     QANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNEK
                     INKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQE
                     LHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARISR
                     KISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETKK
                     KRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDAD
                     DWF"
     gene            complement(32362..33840)
                     /locus_tag="LLB18_000839"
     CDS             complement(32362..33840)
                     /locus_tag="LLB18_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5243858.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(34138..35073)
                     /gene="murB"
                     /locus_tag="LLB18_000840"
     CDS             complement(34138..35073)
                     /gene="murB"
                     /locus_tag="LLB18_000840"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBK5243859.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(35146..36066)
                     /locus_tag="LLB18_000841"
     CDS             complement(35146..36066)
                     /locus_tag="LLB18_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBK5243860.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            36179..36931
                     /gene="xth"
                     /locus_tag="LLB18_000842"
     CDS             36179..36931
                     /gene="xth"
                     /locus_tag="LLB18_000842"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBK5243861.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
BASE COUNT        11103 a         7689 c         6264 g        12064 t
ORIGIN      
        1 aataaataat ataaaaggta aataaaaaag agtggatttc tccactccat gaaaagccga
       61 ctttttggga cgcttttttt tgccaagcct cacattttta tagccaaact tcttttgcga
      121 cttgctgcaa taattggatt ttcttccatt gttcttcttc tgttaaatgg tttccttctt
      181 ctgttgaagc aaacccacat tgaggactga tacttagatt ttccaatggt acaaattgtt
      241 gtgcttcttt tattcgttct tttattttct ccgtatcttc caaatctgga aacttagaag
      301 taactaatcc taaaacaact ttactttctt tgttactcca atgtcttaaa ggagtaaaat
      361 ctcctgctcg gtcagaatcg tattccaaaa agaaaccatc ataatttgtt gaaaacaact
      421 cttctgcaat gggttcatat ccaccggaaa acagccaaga agaagcgtga ttcccgcggc
      481 agatatgtgt tgtgatcgtc aaatcttctg gtttgtcttc cagtgcgtta ttgataatct
      541 ctgtacaaat atgggccatt tctttcggat caattccttt ttgaagaagt gcttctcttt
      601 tagtttgatc agctagaaac gcccaatttg tatcatcgaa ttgcaggtaa cggcaacctt
      661 tttcataaaa agcatgaatc gctgctttgt aagtagagga caagtcctca taaaaatcag
      721 atagatcagg ataaatctcc ttgatttttg aagaaccatc attagatagg atctcttgtc
      781 gtaaaatcat cgtgggacta gggatcgttg cttttgcaac aaaagtatca tctgtttcca
      841 ctacttcttt cagaaaagca aaatctttta aaaatgggtg atttggattg aaagataatt
      901 tatctactac ccgaatatta taagctggtg ctgcttttcc gtggaatgtt tgattatatc
      961 cagtttctgg aacatagcct tcgataccat ttagttcttc taaaaaatca agatgccaaa
     1021 atccacgccg aaattcacca tctgtaattc ctttgatgcc gactgctttt tggtcttcca
     1081 ctaatttttt tatttcctgg tcttcgattg cacgaagttc ttcttttgaa agtaagcctt
     1141 cttgaacttt ttttcttgct tctttgatcg attgcgggcg taagaaactt ccgacatgat
     1201 ctactgtaaa tggtctattt ttgctcattt cactcactct tttctttgtt ttttgtaaaa
     1261 aaaaatcctt ttactagcaa atactagtaa aaggacgatt atactcgtgg taccaccttt
     1321 tttcagaaaa aacattcttt ctctcagcct gacaataaaa tcagtggtct tggtaacgaa
     1381 agactgttcg tttttgccta cctttcgaca aaaaatcctc taaggccatt ttcgacagtc
     1441 aacttctagc tttttacacc aaccaaagcc tctcttgaac cattttctgt ctactttcct
     1501 tctcatcgga tactattaga ataaaattag aatagcatgt ttgaaagaaa agtcaatagg
     1561 gaataagaac aaacaaaaac taatttgtta ttcttagtaa tttgtttgtg gaatacaata
     1621 aagcttttct aatatgataa ttgttcagtc gtcctttcat cttagatcac ttccttaaaa
     1681 tgatcatacc cgtttcaacc acataaaaaa ggacttaatt ttgaaaaatt tcccatcaaa
     1741 actaagtcct ttttattata gttatgcaaa tttgcttatt ttctcgctat ttccgataca
     1801 tcttgaacag gagcaattcg actgaaaaca ctggtgcaaa agcatttatt tgtcttatgg
     1861 tagaaccgtg gaaaactcag actggtaata aattgtcatt ttttgaaaga atagcgccct
     1921 cttgaacatt atcaatcgca cttaccactt gttgatctga ctttgcatat aagtgaccgt
     1981 aagttcctaa agtgatttga atattcgcat ggcccaatcg ttcttgaata gatagcggtt
     2041 gaatattctg ctcaattaga aatgcaacat gagaatgtcg tagcgcgtga agcttaatcg
     2101 gtttgacacc cgctttttta gcagcttctt ttaaccagtt cgcaaaagaa taaggtggcg
     2161 taaatgttcc gtccaactga gcaacatatt caaaatttcc aatacgtttt tgcaagtcat
     2221 accactgtct gagttttaag gaaagcttct tccccaaccc aatcgttcga taagcacatt
     2281 tagttttggg agtcgaaaag taccaatcat cttttgtatt ataaatcaat gtcttctcaa
     2341 tcgttatcgt gtttttctca aaatctacat tcgaccaaga caaagcttca agttctccaa
     2401 tccgaatgcc agtataaaag agcatttcat acacaatctt ccgatggtgg gtttgaatct
     2461 tatcatcctt caattcattc atcacttttt gaaactcact gtgttcccaa aactcaactt
     2521 tcttattctc agaaggaagc gaagaaacat cttcaacggg atttttagca atcaccccct
     2581 ctttaacagc ccgatccaat acaattttta ggtgccctcg aatccgattg atataagatt
     2641 ttgataacgt ttcgccatta acttttttcc gtgaattacg tgactctgtc tggcttagtt
     2701 caaataacca atcctcaata tcgtgacttg taatatctcg aacacgaaaa tgatagaaaa
     2761 actgcatacg cttttcgaaa atgaattgcg cattctcata tgtttgactt ttgacctgtc
     2821 tctcgtacca ttttacaaac ctatccttgt aaaactcttc gaaagtcatt tgattggtag
     2881 aacacagttg attaggaatt gtcttgttaa aatcatgtgt ttccatgtac ttgtcataag
     2941 caattttggc atctttttgt gaagcataac ctcgtttagt cttctgaacc tttcttccat
     3001 tttcatctat acctagatac gctcggaaga accatttttt tgtcttttta tcttggtaaa
     3061 tatttttaat ttttggcatc gttccattcc tccctgtact tgagaaaagc tactttaata
     3121 gtaccgcgct tgtactgttt attccgcaac ttgaatgtga aaaagctgtt caattactcg
     3181 ggatggcacc acaccaactt ggcgattatt ataaaaatca ataccttcaa tccttgcaag
     3241 atatgccttg ctctctttaa tcattcgtgc agcttgacta ggtttaaagc ccatctctat
     3301 caaaattgca cgatttacca tgaaatcaca ttttgtttcc attctctcac ctcctgattc
     3361 tttactcctt ttaaaataat cctctttata atctattgtt tctcattcga tggttgtgtt
     3421 atactcgtct tgtcgaggcg gagtacgttg cacaacttgt tgtgtaagca gtactttgct
     3481 tttttagtag cttgttttct catttgatat actttgtaat tttcgttcat aatactcaac
     3541 ctcctcctga taatactccg ggtctgcctt catattttgg agaagtttga tctgtcttgg
     3601 attcatttct ccttgttcaa taatcaaagg caacaaggaa gaatgaaacg tttgatcgac
     3661 ctgtgcaata aaaactaatg atggtgaaac accatgaatt aaccaactca tagttttctc
     3721 aaaactttga ggaattgtat ctaaagaaat ggtgattgcg ccataattgc taataaaggc
     3781 tgcccatttg gcatcaactt ttgcacctag atcatttgga tcacggtcat aaaaacaaat
     3841 tgctccatta agtaactcaa agaacagttt ggttaaatca tgggtttttg aaataatctt
     3901 tgccaagctt tgcgctttct cttttcgata ccgtagttca aagcgattct ttacttttgc
     3961 ctcttctaaa ggaattcctc gtcgcttccg ttgttcatgg tccttctgat aaaagcaaaa
     4021 acgacactga ctcttctttg agcctaaata caaggtctca ccatttgatt cattgtttat
     4081 gatatccgta ccgccatgag attcactcac ttgaaaagtg gtccacacat ggcctagtat
     4141 taccttatgc ttaagttctg gaatgctgag actccccaca aaatcatcta aagtaaaatc
     4201 aatccgtgta aagttcccct gataatctaa taccttacga aaaaactgtt gccaatttgt
     4261 ttttcgtgtt tttagccatc ttgctaagtg tttacagcct tgacctgaaa actccatcac
     4321 agttccttta accgcatcgt caatggaata ccgaatcgtg attacttgat tccacacgta
     4381 ttggccaata tagccctttg gcgcataatc cagttcctca aaacgttcaa tgggcatttc
     4441 aataatctct tcaattagct ttaaatgttg attcgagaaa aagtgaatgg ttagataatc
     4501 aatcaaaaca cggttaactg gaacgacctc ttcttgcaaa ctatccaaca caagattcaa
     4561 tttttcttca cttaattgtc tcgttccttt ttctactttc gataataact atctcgaaat
     4621 ccccactttt tctgctaaat atcgttgtgt ccaccccctt tcttctcgag aaactcgaat
     4681 ggcttcaccg agatcatgtt gattaacttg gttcatcgac aaacctcctt ctgctattta
     4741 cttgtcaaag aacctattga acttatttta agtacatttt tattgtacgc ctgtatttat
     4801 tttaagtcaa tatgttttga ctttttttaa gtacacacgt atactaaatt taagaactta
     4861 tcctgaggag gagttttcat ggagatagac aagcaagcag tcggcaatcg aattcggcag
     4921 attcgccaag aattaaagtt gagtatggag aaatttggca aactaattgg tgatttaccg
     4981 cgaagtacag tcaataactg ggaacgtggg atcaaccttc caaaaaccga aacccttcac
     5041 caaatcgcag agataggtca tgtcaccaat gaatatcttt tgtatggtga tcaagagaat
     5101 caatacattt tagaaatgct ccaaaaaaag gcaggtaagc ttgatcctaa gattgaaggt
     5161 ctcatagtag acgaaatcaa acacgctgac cttgttagtg aaaaagaaat ggatcgaatg
     5221 attgaatttt ttattacaaa tctcattcca ccaactgaac aagaccagtt tactttccaa
     5281 tgtatcgatg aaaaaaagca gctttatctt ggttcaacta attttggtaa ggaagcccag
     5341 ctctatttgc aacatgataa tcaaaatcat attctgcaca tgatgccctt taccttctcc
     5401 aactttagtg tggatcgcat actcgtctat ttagcaaatc aaaaatccta ttcctatttt
     5461 gggaaacatt tacccaagga actaggtgag aaagccatcc ttctatactc aattaatcaa
     5521 ttgaccagcg atgtgcgaat tgccccgttg gtctattcag aagaaaccgc ttcttatcag
     5581 tacacagagg acaatcaata tctactagaa cagcaatatc tttatctacc attcgtgatg
     5641 gaagtcgaga aagaacgcct gttaaatgca gcgtatccat catcaaaatg aggtgacaaa
     5701 attgataagc acgtgacaaa gaaaatactg ctaggacact ccccaatggg tagttgtcac
     5761 agtttcctgt tctttgttag ccccctgtta gaaccggggg ctttattcct gcagtccggc
     5821 tacgccttcc tgcaatagac aaaactccag atcgggtaat tcgcttgtgg cgaaacccga
     5881 cctggagttt gtctctgtat tttgaaccct aaaaattaat caaacagact gatattctca
     5941 taatcagcgc gaaataagcc attaagtaca gttttcctac ctatttttga taacccgctg
     6001 gttagttaat attccttttc cgagagagat aaatgattgg ttaaatctat atacatctca
     6061 acctttaaaa atgttttcga aatacttcat cagtacatgt catacaaatt accagtgcat
     6121 tctcaaattc tagttcttta attgatttca gttgaggagc agttactttt ggcggaaatt
     6181 tccatttttg tccaaacctc ttcccccgat gaaatttctt tgttgcaatt attgcaatga
     6241 aaaatttttg tttcaaaaat atacataatt acttcctcca ataaaaacta tctacctctc
     6301 aaattatttt tctctaataa gaaaaacaga aaaggtaata agatacaaca gtgatgattc
     6361 ctaataaaga aaagactaca ataatatttt tctaacttat cgccttcaaa gaaatagttt
     6421 cttatttttc actaaaataa aaaatttatt gcaaaaaaaa tagaagtgac aaaattatca
     6481 atcatttcaa ggtaatataa ctacctgagt ttattatcga ttaaaatgct aactacattt
     6541 gcaagagaag cgagagttaa aggtaaatat agaatttcta cttttttagc aatagaaata
     6601 ggaataaaat atttaaaatg tatagaaact ttcttttttt ttcttgctat ctttttataa
     6661 tcacaactct ctataataga attacgattt attttatacg gctgaaaaaa tctatcacca
     6721 aaaaaattca aacattaagc caaggattat gaagtcaaca tttcgaaaaa tgaacataca
     6781 ttggtaagca actataacta ttaccacaga cataaagtaa cacaatatat tactatttaa
     6841 gtgtacgcca ccagtgaata tcctcaaggt atacagcgca caacaaaaag aaaaaaggaa
     6901 acgcagaagc atttcctttc agtgatttaa tgaaaacaac acgatttgac ttagagcctt
     6961 tttatttgaa ttcattttcg ctttatccaa cttcatttga tcatttgatt actcggttaa
     7021 atacttttga catgagtatc aatgaaacat tcattaatta tggttgctta tttcttaccg
     7081 cttttctggc caatgctaat ccgccgatta ttccggcatt atcacctaat tcgggcgtaa
     7141 taatgtagct atcaattggt ggtatttcaa catatccatt tataagctca acaaatttat
     7201 cctgaacttt tttcttcatg tgttcttgtt tcattacacc accgccaaaa ataattctat
     7261 ctggcgaaaa catcagtgtt gtattgtatg cacattgggc aaggtaaaag gcttcaatct
     7321 gccaaaacga atcgtcagcc aataaattct ggccttttac acccaaccgt ttttcaatcg
     7381 ctggtcctgc tgccatcccc tctaaacaat cttggtggaa gggacagttt cctgaaaaat
     7441 tgtcctttgg atgtcgcttg atcaacatat gccccatttc cggatgactg aacccttcca
     7501 cgaaagtccc attgaacaag gcaccacctc cgatacctgt tcccacagtg aagtatgcaa
     7561 cacctgctaa ccctttgcca gaaccagcaa catattcacc atagcaagcc gcattgacat
     7621 ctgttgtcca ttcaatcgga atattgaaat attgctttag cgttcctaca aaattgaaat
     7681 tttgccaagc aagttttggt gttgatgtga tatgaccgaa actcgttgat ttgcattgaa
     7741 tatcaattgg accaaagcag ccgaccccga tgcctgccaa ttgttcctta aaaggtttaa
     7801 aaaaatcaat gacctgcttc attgtttcaa ctggagttgt tgtgggaaaa ctgactcttt
     7861 ccaaaatcgt taattcctca gtaccgactg cacagacaaa tttagtccct ccagcttcaa
     7921 ttgccccata tatcatcata ggttcctccc ttcgaatatg tgaaaaacac ttcattaacg
     7981 cggcaagcgt tctcgatcag tgaaatgacg tttagtattt cctgaagctt ctgttgaata
     8041 ccagtaagcg acactagcaa catcgtcttg ccgctcaaat aagcgaacat catcgttgcc
     8101 gatttgttgt aaagtgaccg ataaatcttc ggtaaaacag atggggtctt gaagatgcca
     8161 acgataaaga ccatgtcgtg gcattgcgtc gtcaccaaag gcatgaacgg cattcaattt
     8221 tcccgtttca aaacgatctc ttgtggcatc tctatttgat tggtaaggat accctaaaaa
     8281 ggctgttgaa tagtttttcg catgtggacg tccgaactca tcgtactcat gaaaggccca
     8341 cgccccgcca aaataatctt ctgaacctgt tgaggttacg gtcggatact cactatcccc
     8401 atcaatgtag aatttaaact cgccttcgcc ccaccaataa cgttctaggc aggtaagcgc
     8461 aaggtaagta cccacgtaat agccttgacc ctttaatcga tcaattaact tataatcctc
     8521 ctgtaatttg gtaatgcgtt cccgatgcca atttgcgtga aaatataggc tattttcttc
     8581 caattcgtcc accaaagcgt aatttatcgt ataaaaaaat gaggacatat ccttcggatg
     8641 taaattctcg atcgtaattt tagcggatgt ttggaaaggc atttcgaaat aggaattaaa
     8701 gccccctgta ggattaacca ctatcggcaa cgagttcacc tcgcaacgct ctccaaaccc
     8761 attacaaaag aaatccccta aaggactttc aacagcaggg ctatccgacc catcccaata
     8821 aattcttaag attaaatcac gtaaaacaaa actgccaaat tctgttcgat cacgaatcgt
     8881 catccacata tgacgaatta ttcccgttcc agtaatatcc gcaatcacag tttcttcacc
     8941 agaagtcagc ggaattgcgc cacgaccttt gcggcttggt cctagctcgc ttggcaacat
     9001 cgcagcttta cctttctcgc ctgttggatt ttcgggagtg attgctcgac tctggatttt
     9061 tttaaattgg gtaatatttt ttagtatact catctttttc tcctttgaat gtgaatcgtt
     9121 tttccctttt ctacgtgaag aatttttttc gtatcactta ttttcaatgg cttttctgac
     9181 aaatttgaaa tactcaactc ggattgcgta cattcaatcg aaatgaaggc ttgaccgaac
     9241 ttcaaattct tccaagaaaa cgttaaatta tcaacaggat caatttgcaa tactcctttt
     9301 ttgaatttca atccgaaata ttgactgatc attaggctga caaaaagacc cgatgcccag
     9361 ccgcatttgc cgcagccaaa gtctcgcacg acttctcctt gttgagcctc taagcgatac
     9421 ggccaccacc accacgaacc gtctaaatct gccaaacaaa ttagttcttc taatcgggtt
     9481 acgaaagctt gagggttgtg cagctcgctc attaaaacag tgataaagcc aggaaaagtg
     9541 gcgccggatt ctaatcccca agtgatgcct ttgatttcct cgctataggt tggattgaaa
     9601 gaactagcag aaaaggccat ggtgttctga tataaatgat ctttattatc taaaaattga
     9661 taaaaaggca tcaacgtagt gtctgattct tctccatcat gcatcaataa attaattttt
     9721 ccatccacaa tcacatcact taaaaagatt aacccttgct caagaatcgg tttttgatag
     9781 tgcttcactg aataggttgt tttctcctca tcaccgattc cctccaaaaa ttgctcacca
     9841 aaaggaccat cgatagtcat ttgtttacaa attgattcct ttagtttaca ggcaatgttt
     9901 ttgtatcgct tgctaagact cagttgttct agggcttcaa aaatttctgc aagtccaata
     9961 caggccttcc aaagacaaag attgctgccg gtatgatact ttccaagtgc aaaggcgtct
    10021 gataaccaaa cagatggaaa aagcattggt tcccctgacc gacgttgagc taatatgtcc
    10081 tcaataattc ttgaagcatt cagtagaacc tgcggacacc gctcaaagaa ttttgtatcc
    10141 ccagtatgtt caaaataaag actagccagt aacgcactgg ataacgaatt actcagagaa
    10201 tgattgatac ctcctgtaaa ttttgaacca ggaaacttaa cgccatattg atcaaaccat
    10261 agaaccgttt tttgacataa ctccggttca aacatggtga atggcaatga tgcgtaatac
    10321 atatccttat tccaaattcg attagtagca ggatagctgc cccaattgct gccgacgacc
    10381 tgtccctgtc gattcatacc gaaactagaa aagctttgat aaagtgcacg acgatagaga
    10441 tggacaactc tatcgtttgg cattgacagc tgcccaaata gctgagcaaa atagttcaat
    10501 gtttccttca gccatttttc gatatcagat tcctgaaaag tcattacttc ttcaaaagca
    10561 tttgggtcca caaaagcaat ggcgaagctt gccacttcct gttgtgcgat cgtgtcctta
    10621 tttccttttt gagaaatcaa cacattttgc tgatccgaat acttctcttg atacgaaggc
    10681 acatctttca ctgaaacttg aaggctttcg tgtgtttcat tcacaatgta aacctgttga
    10741 acaagcatac ttaaacgctt attagccagt atgggagcaa aggatactac aatgacctta
    10801 aacgtcgaat aatgatgaat atatctaggc aaacagtctt gaatcacatc gacttcaata
    10861 cgatgatccg attctgacaa atggtagaca atcccgttta cttcaacctt taaggataac
    10921 gaattggttt gagagagctg tttattgacc caaacacctg gtttttcctc agttagtaaa
    10981 ttttctcgat aaaaggtcaa cgtttgaatc gtcccgcaaa catcaaggtt tgctaatgtc
    11041 ttttgattac ttacatcgaa ggtcaatccc tttacatcag gaatattccg atagtagctg
    11101 tattcgtttg aagtagtcac atttccgtcg tttaactcag cattaaaaaa tgggtgtttg
    11161 ggtgaataaa ttacttcatt aatagtcatc ttttccctcc ttgctaaaaa aactgcagcc
    11221 tagtagctgc agcttcctac tatgcgattc caagtaatga caataaaatt cccaagacga
    11281 ccattccaaa aataattttg atgacgccga cttttttatc tagtaatttg aaacagctca
    11341 atgttaccaa taacggtaca attcctttaa aaatactatc gaggatttct tggacattca
    11401 ttagttcttc gcccttcatt gaaaagctca aaacggtatt gaatttgacc atactgatcg
    11461 tcattgcacc taccatgatc agacccaaga tactagcagc ttttgtcaga atttcaatta
    11521 acccgttcgc atacagcttt tcaatatatt tagagcctaa tgaatagcct aaaacgccgc
    11581 catagtatcg catcaagtaa ttaggtatat tgaacataac taaaaagata attggtgcca
    11641 aaatatttcc ggcattggct aagttgatcg ctagtcccgc ggtaacgaca cgccaaactc
    11701 cccagaacaa tgaatcgcca attccagcca atggtcccat caaactcgtt ttgatcgcgt
    11761 tgatactttc cacgtcaaaa ccagcttttt cagaattttc cttctccatc gatgccgcaa
    11821 tccccatgac aaaggacgcg caaggaatgg tcgtcgaaaa atactgtgta tgacgttcca
    11881 gcgccgcagc tcgatcttct tcacttttgt agaaatgatt aatgaagggc atcatagaat
    11941 aggcgaaacc accgccgccc atcgtcaccg gattcaccga agcatacata gtcatcgagc
    12001 gccaaaacat cttccgaacc aattttttct catctttaga aattccatca gctaatttca
    12061 ttgaaagaaa tcctcctctt cttggtcaag cgttgcattt acagcagcat cgctttgaac
    12121 tgcatgaaca gatatatttt ttagttgtag atctctttgg gctataacaa ttgcaataat
    12181 cgttccaact gcggcaattg caatcaatgg taactcgaga tacgccataa caacggcccc
    12241 aaagaaaaac cacacagcaa tatttttact ccaaagcatc cgtaacagca tcgccatccc
    12301 aactgccggc agcagatttc cagcgactgt taatccgttc atgatgacct ctggaatatt
    12361 atccaagacg cttttgacaa catctgctcc aaataaaacg gcaaagaatg gaataagagc
    12421 ataaagcgca tagtggacaa accacataaa gaagtgcaga ttgatgattc ctttttgatc
    12481 accagatttt gcaaatttga aaaatttagc agccatcggt ccacatacaa aagaaaaaat
    12541 catattcatt aactgtaatc ctaatactgc tagtggaaag acaatgggaa taatcgcatc
    12601 cacgtttcct cccattttga ttgcgaacgc tgtagccagc ccagcagcca aagaaggctc
    12661 cgccgtacta gagattccga tattgacgac acccataaag atggcttcta gtgacgcccc
    12721 gacaatcaac cccgtctgca aatcccccat caacgctcct gctaacggag caacaacaat
    12781 cggacgactc agcatggaca tcccgaacat ttcatgtcca gcaactccaa taaaaacggc
    12841 caaagcgact acaaatgcat catacataat ttttctcctt cctttttcta aaaatcactc
    12901 aaaatagaga tagctgaacg tttttccatc gccggtgtag gctgaaaaac ggtatctgga
    12961 taaagttcaa ctaattcttt taagtcttga atttctgacg tcgttaacat cacttccttt
    13021 gataaggttt tcttatcttc cgatggcggt gtcattttcc cagcattccc cacgttcatt
    13081 aattcgattt ccgttgggaa agctttcgca acttttaccg catctttgac attagggact
    13141 aaaaccatca agcgcatgtc cttcgcccgc ggatctttta acaaatgaat cgcgtcatca
    13201 actgttttaa taatgacttt gacattcgat ggtgcagcca tcttcaatgt catcttttga
    13261 atatcgttgg tagccgcctc atcgcttgct actactaacc cggttaaatt tagactcttt
    13321 gtccaagtca tcgctacttg tccatgaatt aatcgttcat caattcgcac tgctttaatc
    13381 atttttcttc ctcctaaaaa aaatcttcct cttcatttac tacatgtacc tcatcaagaa
    13441 tggtcatctt taattcctgt tggcatttat ttaccagttc ctgaatatcc tcctttgtta
    13501 attccttggt tgccaatact atttcgagca gaattggcag attaaagcca gacaaaatag
    13561 ttacagcaat ctctttctcc aaaaaggttt tggtaatctt ctgattgaca cttccgccaa
    13621 ataaatcggt aaaaacaaaa atctgatcct gctcgttcac ctggtttaca aatacattca
    13681 actcctgttc aaaatcacac tcatccacat aagcattaat caccgtaatc tcttgaacct
    13741 tccccgtcag taattgaata ctgctaagaa agcctgaagc taagtgaccg tgagtcgcta
    13801 ttagaatttt cttcatatgg ttaattcctt tctttctgtt cacttttata taagcaattc
    13861 ctgtgccaac ttttaaaaac attggtttaa tcacgttaat tcacattaaa aaaagtgtct
    13921 aacctaaaaa aaacagatta gacacttttt tagacacttt atttttgaat atacggtcct
    13981 aataattcat agagcagcga aagctcataa gcattgactt taaaattata tttcatctcc
    14041 attgattgaa aaatacttct agaaacataa taaaattcat cttcatctgg tttcaaatca
    14101 taattcggtt cttcagattt ttctgtccga gccaagaata aacgttccat catcaatgcc
    14161 gtatgcatat agagatttag ttttacacgg ccatttaaag tgaaatgata gtaattttca
    14221 tatttagaaa tgactgtttc cacttcactc atcacgatcg ttgggttcag aaagttcaaa
    14281 cggtccgcaa ttccttccaa cgaaaagaat tttactagct cctgaatcaa gcggttaaat
    14341 tctgccggct tcatttcagg actcaaaata tgctccaaat tggctgctcc atcaccgtct
    14401 aagatgtcat aaacattaat attaggaatt gaaaaggaac gtggaagatc cgaagtcgtg
    14461 atgaccaatt ttgtcttgtc aaaataagtt tcatcatttt ggtcgattaa ttcacgtagt
    14521 tctctgtagt ccttcgtgaa aacttcgatg gattcatccg ataaatgatg acgaaaaaca
    14581 tctttcaatt tgtccgaaat ccccaaaccc gacatacagg aaatgataat gttgctactt
    14641 tgagaaaagc cttcaaagta ttgaacattg attgaatact tgtctgctgc atcctccgca
    14701 atctgtttaa atggcgcatt catcgtcatc ttcaagccaa tatcaagtgc aatggaagtc
    14761 gtcaaattat tcagaagaag taactcccct tttaaatcgt tcttgatctg tgtgtaaatt
    14821 tgatttaaag agcccatatc tacgatcagc actagactat ctgtattcac ttgccgtttc
    14881 acgaaattcc ttgtcgattc gacaatctct gacacattac tctctactgg catatccaac
    14941 gcttcaaaaa cataattgcc gcataattga ttcactactg cttgaatgct gctagccgta
    15001 ctatctccgt gagcaagcaa caggcccttc agctcgatgg attcatctac ataatcagat
    15061 aaagtcacga caataagcag tcttagaaag ttctcgtcct tttctgagag cggtggtaaa
    15121 tgctccaaga actgattaca taagtaagtc gtccgaggta gatttgcagc taatgtacga
    15181 tttatcccgg ttaagtctgt cttatagctt ggggaaatga cataggatct gctaataatt
    15241 tctgcaacag gtccactcgt cgtcaatccg tacgtttttc ctaaaacgga tacccagacc
    15301 tttctaaaca tctgaatcat caattttcta ctcattgata aaaaagaatc cttatcaatg
    15361 tgatgcacca aatgctgtac ttcattcttt atcgaagaaa aattttcatt gaaattacct
    15421 tcatttatca gctgagtaat tttttccaaa atcgaatcat aatcaaacgg tttgattcga
    15481 tccgttttta tcttttgatt tttctttatc aataaactag caatcggcaa gctttctact
    15541 tcggattcca gcatatttaa ctgaatcaag atctcatttt tcccaatcgt taatggttct
    15601 tcttgtgttc gactatacac atccgcacaa ctgattttaa tgatattctt cagcttacca
    15661 atattcccac taaagggatg agataacatt aaagacaagg cttctcttga aacaataata
    15721 tctttttgta aaacatccgc ttcattttga aaaaataatt gaatcagctc taatcgttct
    15781 cgaatggggc gatcttcaaa agttggcaac ataacactaa tttgaatacg ccgatcaaag
    15841 gtgtctaata aataattttc acctttttcc gtcgtggcga aaataaaacg aaccttagca
    15901 gaatgccaat ttacattttc accgactgga cgatagtttc cagtatcaat aaatagaaag
    15961 agcttttctt gattttcttt cgataggcga tggacctcat cgagaaaaag atagccgttg
    16021 ttggccgttg ccaataaacc atcggtatcc ttttcagccc ccgtaaaggc ccccttcttg
    16081 tatccaaaca gtgttgccga aagcagttcg ggattgtccg cataatcggc acagtttaag
    16141 atagcaaatg gtgcatcttt ttcaataatt tgctcatgga tagcgtattc aaaaattttt
    16201 gtggctaaaa aactttttcc aacacccgtg gctccattta ttaatacact gagtccgtta
    16261 ggcggatatt tgacagcggc tatacatttt tgaatgacct ctctcagact tccgtcatga
    16321 ccaactacag aatgaaaggc ttcgtttatt tgctccgtat tatctacaac cgcatattca
    16381 tctaaaggct tccacaaaac aggctttccc ggtaatttct cgaccttttt atcttccact
    16441 aatctcgtca aataatggct ggcattctga cgagagatac ctagattctt cgaaattttc
    16501 tcggcagtga cagaagacat attccctgtt agtcgtatca gctcatcaaa aactcgatct
    16561 ttagcgctct ttttcatttt ttcctccagt ttaatgtgtc taaaagcata ataaactatc
    16621 ggctgcaata tgtctattct atatttgtat tccaattttt actttgaaac acaaatagtc
    16681 gaatatttgc ctcagatatc tgacaaaata atttatctac caatttagtt tttatctaat
    16741 atgattttta tgttttttca tagctacaaa tattgaactg gattcatata ttagttttat
    16801 taatagatta cagaagggtt aagtatattt gcatagtttc caattacttt atccttctgt
    16861 aactttttca atcttagatt tactagcccg tctcgggccc tattttacaa tggttttgtc
    16921 cacttttctc tggtagaaaa acgtggtaga aaaaataaaa taacacaaaa aaagcggcgt
    16981 ttcatccgct tttggtagaa gattggaaaa ctcagataga aaaaggacga tttttagctc
    17041 tttagaacgt tgataagtcc ccattcttac tgagttttgc cattatctcc tatacatctt
    17101 gaattctaag aataggtcat tatagatgcc taggtatttc gatcctagat ctttgtagac
    17161 ttcaagatgg gagatcgtgt catcagatgg atagaattgt tcgtccgacg aaatgtcttt
    17221 tggcaataac gcttttgctt cttcatttgg tgtagaataa ccaatatact ctgcattttg
    17281 tgccgcattt tccggttcta gcataaagtt gatgaaatca taggcacctt ctttattttt
    17341 cacggttttt ggcataacga tattatcaaa ccaaagattg gatccttctg gtgggatcac
    17401 ataatgtaaa tgttcatttt cccacatcat atcggcagct tcgccagaaa atgtcactgc
    17461 cacggaggct tcttcattga tcatatacat tttgatctca tctgccacga ttgctttgac
    17521 atttggtgtt aaatgattca atttatttgc tgcttctgtc agctgtgcca tattcttact
    17581 attcaaagaa tagcctaaac tattcaaaga aagccccata acttctcgtg caccgtcaat
    17641 cagcatcaaa ctgtctttta attccggctt ccacaaatca tcccaatgct taatttgatt
    17701 tgcatcaaag aatttatcgt tatatacgat ccctaaagtt ccccaaaaat atggaatcga
    17761 atactgatta tctggatcaa aatccaagtc taaaaatcgt ggatcaatat tatttaatcc
    17821 tttgatcttc gaatgatcta atggaagtac tagtttttct ttgatcattt tttggatcat
    17881 atattcactt ggtatagcga tgtcgtagtt tgtcccacct tgctggattt ttgtgaacat
    17941 cgcttcatta gaatcaaatg tttcataatt cactttgtat ccatattctt tttcaaattt
    18001 cgtgatcaaa ctaggatcga tataatctcc ccagttatag atggtaagta cctttgctcc
    18061 actcatgcca cttgtttttt caagttgacg aacaccaagc agcagcaccg caataatgat
    18121 gagaatacct aaaaacagag attgtaattt tttcatcgca gccgtgccac cccctcgcgt
    18181 actcttctgt ttttcttcag ccgttttgga cggttttctt tactaataaa gtagtatcca
    18241 atgaccaata tcatggagaa caagaaaact aacgcactta gcgcattgat ttctaaactg
    18301 attccttgtc ttgcacgaga atagatctct actgagagcg tcgtaaagcc atttcctgtg
    18361 acgaaaaatg taaccgcaaa atcatcaaga gaataggtaa atgccataaa atatccagct
    18421 atgattcctg gagaaagata aggcaaaatg atatttttga ctacttggaa attattagca
    18481 ccaaggtctc tagccgcatc gaccattgaa tcgttcattt cctgcaattt tggcaagacc
    18541 atcaagacga cgattggaat gctgaaagca atatgggaaa gcaatacact ctgaaaacct
    18601 aatccgaatc ctagtagtgt aaagaaaatc aagaaactag caccgataat aacatcagga
    18661 gagactaata agatgttatt catgctcaac aacgctgtcc gtgcacgtcg ttttttcgtg
    18721 taatagattc ccatagcccc aaatgtcccg atgatcgtgg cgatcaatgc agataagaaa
    18781 gccagcatga acgtattcaa tacgataatg atcaaacgtg tatcttcaaa aacagcttca
    18841 taattttccc aagtaaatcc tgtaaagctg ttcatcgttc ctccttcatt gaaggaataa
    18901 aaaatcagat agaagatcgg tgcatataag aataaaaaga cgatccctaa ataaagatac
    18961 gaccatttaa attttttcat ttatgagcga cctccttttt tcttctcgcc tgtcaggagc
    19021 atcacgatga acatagcaat gattaaaatc acaccgattg tagaacccat cccccagttt
    19081 tgtgtaacca agaaatgctg ttcgatagcc gttcctaaag tgatcacccg atttccgcca
    19141 atcagacgag tcagcatgaa taaagaaaga gaaggaataa atactgcttg gacaccactt
    19201 ttcacaccat ttaatgataa cggaaaaatc actcgtcgga aggtctcaaa gctattcgcg
    19261 cctaaatctc tactagcact gatcaaagaa ggattcatct cttccaatgc attgaaaatt
    19321 ggcataatca taaatggaat ctcgatatac gttgccacga acagaaaact gaagtctgtg
    19381 aataatatct gtttcggccc gatcccgata aaatcaaaga aatgattcac gctgccgtgc
    19441 acactgaaaa tcccaataaa tgcgtaagct ttaagcagca gattcaccca tgtaggcaaa
    19501 ataatcagca tcagccataa ttgcttgtgc ttcagttttg ttaaaaaata agcagtcggg
    19561 taactgatga tcagcgtgaa aaacgtgatc aaaaatgcat accatacaga attgatcgtc
    19621 atagaaagcg atgtccccga cgtaaaataa gatagataat tattcagcgt gaattgccca
    19681 ttcatatcaa aaaaagattg ataaatgatc attaatacag gcgcgatcac gaataaaccg
    19741 agccacaaaa tataagggac ggaatagatc ctgcgcattg ttttcattct tgtcccccct
    19801 attcttcgta gctgtcaaga cgtgcatcga attcttcttc agactcgttg aaacgcatga
    19861 catggatatc ttctggctca aaggccaatc ctactttgct tccttcttta gcttttttcg
    19921 ttgaatggac catccattca ttttgctgtt catcataaca gatgatttca taatggacac
    19981 cacgaaacag ctgagtatcg accgttacga ctagttttcc tttatctggt gtcgtgatcg
    20041 tcaaatcctc tgggcgtaaa acaacttcaa ctggttcatt tagacgcatc ccgccatcga
    20101 cacattcaaa ttgcttacca acaaactcaa ctagattatc ttcgatcatt acaccgtcca
    20161 cgatattgct ctccccaaca aaatcagcaa cgaaatgatt gattggctca tcataaatat
    20221 ctacgggtgt accactttgg acgattttcc ctttattcat gacaaaaatc tcatcactca
    20281 ttgccaacgc ttcttcttgg tcatgagtaa caaaaataaa cgtgattcct aatcgttgtt
    20341 gcagatcccg cagttcatac tgcatatctg tacgtagttt caaatcaagc gccgataacg
    20401 gttcatctaa tagcaatact ttcggttcat ttacaattgc tcgtgcaatc gctacacgct
    20461 gtctttgacc accagacatt tcactaatct cccgtttttc gtatccagga agctggacca
    20521 tacgcaaagc atcttttacc ttcttttcga tatctgattt ggacattttc ttgatcttca
    20581 atccaaaagc aacgttatca aaaacattca tatgaggaaa aagtgcataa tcttggaaga
    20641 ctgtatttac ttgtcgctta ttagctggca aatcattcaa ccgtttccct tcaaaataga
    20701 tgtccccttc tgtagcttcg gtgaatccag ctataatacg taggatcgtt gttttaccac
    20761 agccggaagg accaagcagt gtataaaatt ttccttgttc gatctcaaaa cttacttttt
    20821 ttaatactgt ttcatcatca tagcgtttca ctacttgatc aaatgaaatg attggtttcc
    20881 ccacgttttt accccctata ttacaaatat gattgcgttg caacaatcaa tacttttgtt
    20941 cgttttttga gatgattcct taattgatgt tgttttgtcg cttgataata gatcgactgt
    21001 cctgcttttg ccacatagac cgtctctcct aagcttaact ctaattcccc ttctaataca
    21061 aaaataaacg tttcagataa tgaaggttca aacgtcttat attctcctgc accttcaaaa
    21121 gtcagcaaga caggctccat ttctttttca ttcgaatcag ccacgagcca ttccaattca
    21181 tacccgtttt cttcatcgaa ataaaccgta tgatcttctt ttgaataaac cacttgcaga
    21241 ttcgctgctt cttgatgaaa aaattcttct ggagtcacac ctaagacttc aagaatagaa
    21301 aagaatgttt ccattgatgg tgaacttaaa tctcgttcca actgggaaat ataccctttt
    21361 gacaaatctg tgcgttcgcc tagttcttct tgtgtcaaat tcttttggat gcgcaaattt
    21421 cttaacttct caccaatttc cataatttcc tccgaatcga agttttctaa tagtaaactt
    21481 cctgtttact accactcgta ttagtatacg aaatttattg aaaaaggcaa ccctttgtaa
    21541 aatttttttt gctgaatatt tctttatctt ttggaataaa ttctagttgt ttgattcttt
    21601 atttttcacc taatttttgt ctaaatttac ggaagaacaa gaataaaaga gtaggcttta
    21661 tggtatgata aaagaaaatt ttaaaaggag tgtctcacga atgaacgctt ttcgatcttt
    21721 tcaggtaata aaggaacctg ttttccatac agcaatcagt gatctgccat ttactgagtt
    21781 ggctgaaaat gaagtcttgg taaaaattgc ctattctgat gtcaattata aagatgcatt
    21841 ggcaatgagc gagtctggtc aggtgatacg aacatatccg atgactccag ggattgattt
    21901 atccggaact gtcgtccaaa gtaacaatcc acgtttttca aaagaagatc ttgtacttgc
    21961 tactggtttt gggcttggcg tcacccatcc aggcggttat agccaatatc aaaaagtacc
    22021 aggagactgg ttagttcctc taccaaaaaa tatgacgctg cgtcaagcga tgatccttgg
    22081 tacagcaggg tttactgcta tgttgtgtgt gaacgcttta atccgtcaag gtatgacctc
    22141 cgataaaaaa gttgtcgtta ctggtgcttc tggcggtgta ggcagtacag cgatagccct
    22201 gttacataaa ctaggattcc agtcaatcat tgccttttcc agaaaagaag agtctgtcac
    22261 atggctaaaa agtctaggtg ctttgcaagt cgtacgacct gatgaatttc tgccagagac
    22321 aacaaaagct ttaggaaaac agcaaatcga ctatgtcatc gacacagtag gtggcgagca
    22381 gctaagcagt cttcttccat tgatctctta taacggtgca gtagctttat gtggcaatgc
    22441 tgggggaatc aaactaaacg cgactgtctt gccttttatt ctgcgaaaca tccagttgat
    22501 tggaattgat tctgtcaatg taccaataga tcaacgtctt tctttatggc aacagatggc
    22561 ggatttgcag attgcagatg aactggtcgt ccaagagatt actctggatc aattgcctga
    22621 aacagcatct aaactacttg ctggaacaca ccaaggaaga acactagtaa atgtaggtga
    22681 ccataaatga agattctaat cacagctgga ggaacgactg aaaaaatcga tcaagtacgt
    22741 gctattacaa atcattcgac aggacgatta gggcaagcat tagctgatta tttagctgcc
    22801 aatccggata ccacaatcga ttacgtgact acgaaacaag cactgaaacc gaaaagacac
    22861 tccaatataa cgatttatac gatcgaatct gcactggact tatttttaca attagaagaa
    22921 ctaacgaaaa aagaacacta cgatgcgatt atccacagta tggcagtcag tgattttact
    22981 cctgctttta gtttttcaga agaacagctg gcaaaaaacc tacccacttc ttcaacgcaa
    23041 gaagaactgg acaattggtt tgcggaaaat gaacagacag ataccactgt ttcaaagatc
    23101 tcttctaaca ccgagcatct tgtgctcgtt ttgaagaaaa caccaaaaat catttcttat
    23161 ctacgtgaat ggcagccaaa agcaaaaatc attggtttca aactattagt agatgtacca
    23221 aaggaatctc ttctggcagt cgcaaaaaat agtctgataa ataacaaaac tgattttatt
    23281 ttcgcaaatg atttgacgga aatccatggc gagacacacc acggctatct cttatctaaa
    23341 gatggaacag tggaagaagc tcaaagtaaa tctgagattg ctgcattgat tactgagaaa
    23401 attagactgg aggaatcaaa atgaaaaaga tcttactagg cgttactgga agtatttctg
    23461 cttacaaaag cgctgatctt acaagtcaat tcgtcaaatt aggtgcccag gtagatgtga
    23521 ttatgtctaa aagcagcaca cattttatca cgccattaac cttgcaatct ctgtcgaagc
    23581 gcgcagtcca tacagacgtc atgcaagaat caaatccgca ggtaatcaat catatcgaac
    23641 tagcaaaaca agctgacttg tttctcatcg cgcctgctac agcaaacatt atcggcaagc
    23701 tagcaaacgg cattgcagac gatcttcttt caacagtcgc aatggcgctt ccagtgggaa
    23761 caccaaaatt gattgcccct gccatgaaca cgaatatgta tcaaaacccg atcactcagc
    23821 gtaatctgga aacattgaga tctgtcggct atcaggaaat tgaaccaaga gaatctcttt
    23881 tagcttgtgg agattttgga aaaggtgcct tagctgatat tcagacgatc atcgaacagg
    23941 tcatgctgac tcttaatgaa agaaatgctt agaaaaaagg agtacttatg aaaaatacaa
    24001 aaaactttac attaactgcg atgtttttag ctattttgat tttattagct gttacgcctt
    24061 taggttttat ccctatcggt ccaatcaatg caacaaccat gcatattcct gtaatcattg
    24121 cttcgatcgt tttaggacca agactaggtg cttttcttgg cggtacattt ggactgatca
    24181 gcatgatccg tagcacagtt atccaaacac ctttgtcttt tgtcttttct ccgtttatcc
    24241 cagtcatcgg aacagaacat ggaagctgga aagccttgct gatcgcgttt attcctcgca
    24301 tcttgattgg ggtggttcct tatttcgttt ataaaggtct gcgcaaacta atgaaacaaa
    24361 aagcagattc cgtttcttta ttcttagctg gactttccgg ttcattgacc aatacgattt
    24421 tagtgatgaa tatgatctac tttttattcc agcaagatta tgccaaagtc atcggaacaa
    24481 atttaaatgc tgtttattca gctattctag cggttatttt tacaagtggt atacctgaag
    24541 gaatcgtcgc aggtcttgcg actgcagcag tatgcaatgt cttgttaaga tacttcaagc
    24601 acccttctct tactaactga tagtcatcgt agccgatctc tgattttttt ctcttttggt
    24661 gttactattg aatggaaaga tttgacgtcg aaaggatgat ccaaatgaaa atttttgttg
    24721 taggtgcaaa cggacaaatt ggccgacacc tgataaaaga tttagctcca agttcccatg
    24781 aaatttttgc aggggtgaga gatgttgctt cccaaacatt agtaaaaaaa gagaatgttt
    24841 cgtatgtctc ttttgattta acttggtccg tggaaaaaat gaccgaagca ttcaaaggca
    24901 tcgatgtatt gatttttgct gccggctctc aaggaaagaa tcttctgcaa gtagacttgg
    24961 atggcgcaat caaaacagtg atcgcagctg aaaatgcgca tgtctctcgc tatctgatgg
    25021 tcagtgctgt ttatgcagat gaaccagcaa aatggcctga gtccatgaca gattattata
    25081 ttactaaaca ttatgcagat gaatggctga aacgaactaa cttagatttt gtcattcttc
    25141 aaccagtcac attgactaac gatgaagaag ttacttccat tcaattaact aagcctaatg
    25201 agaaggcatc aaaaacgatc actcgctcta cagttgctgc tgtacttgcc gctctagtgg
    25261 aagaaacgga tatttctcgt acgactctag tactttctga aggtagcaaa gagttgaata
    25321 cagcattcca agaatgggca aaggaggaat agatccatgc gtgccatttc aatcaagcat
    25381 cctggttctg tagatgtatt agaacaaatt gaagtgcctg ttcctaaacc aaaacaaggc
    25441 gaattactga tcaaagtcca tacagcagct gtcaatcgaa cagatattat gaaaagagaa
    25501 tcagtctctt tgaaacctcc ctaccctatt ttgggagtcg aagtagctgg agaggtagtt
    25561 gagaataaaa gtgatatctc cacttttact cctgggacaa aagtatacgg attagtcaat
    25621 ctaggtggtt atgccgaata tgctgtgatg cctgccgatc gtgcaatcct tctccctgat
    25681 acgctagact atgtttctgc tgctggaatc tcagaagttt ttttgactgc ttatcaaaca
    25741 ctttactagc ttggaaaatt acaagaaggc gaaactgtct tgatccatgc aggagcaagt
    25801 ggtgtgggaa cagcagcgat ccaattagct agacagcttt ctcacgcgaa aatcatcgtt
    25861 actgcaggat cagaagaaaa actcgccttt tgtaaagaac ttggtgcaga tgaattgatc
    25921 aactataaaa aacaagactt tcaagaagag gtacgaaaaa tcactgaagg tcggggagtc
    25981 gatgttattt tggatttcat cggcgcttct tactgggaaa agaatttagc ttctatagcc
    26041 gttgatggac gttgggtctt gattggtatg ctaggtggga ccatcgtgcc tgagatagac
    26101 cttggtgtat tgattgggaa acgtgtccaa ctgcttggta cattattgac acctagaagt
    26161 gatcagtata aagcagagct cgcacaaact tttatgcaaa aagctgggcc ttttctagaa
    26221 aatggcaaga ttcggccaat cattgaccgt acattccaat tcagcgcagt caaacaagcg
    26281 catgaatata tggaagcaaa caaaaacatc ggaaaaatca ttttgaagat aactgaataa
    26341 aatcatgctg atcaaaaaag aggctgggac agaagcgttt aactccaaga aataagaaga
    26401 aattcacgaa aattgctttt caaatttttg tgaatttcag cttatttccg aaggaatttc
    26461 ttctgcttcc gccgtttata cgtgtttaga gcgtgagaca aaagtgttct ttacttttgt
    26521 cccacgctct ttttccgaat aaacggtgtt caaaagcttg catctgcggt aataagtcca
    26581 accaagttaa aaacataaga agctgttttt acttggctgt tcttattact tgatgcaggg
    26641 cagctttttc acaacctctt cactaaacag tgttcaatca gctgaccctc ggtattagct
    26701 caaaacgctg atttcacaac ctctttttat ttacgttcta tttcattcat tttccgaagc
    26761 aaatcgagct gcttgtatgc ccgcttgtcg cccaaaaata atgatctccg caactgaatt
    26821 tccaccgatc cggttgtttc catgtaagcc acctgtgact tcaccagcag catataaccc
    26881 cctaattggc tggttttctt tatctaatac ttcagtgttc gtattgattt tcacaccgcc
    26941 catcgtgtaa tggattcctg gtgcgatttt gatcgcataa taattcggag acgataagtc
    27001 atgttccatg gctgtggcac ggttgaattg agcatctttt ttctccgcaa catccgtatt
    27061 ccatccatca actgtttttg ctagtgtttc ttttggtaaa tcgatttttt ctgctaattc
    27121 ttccattgtc tttccagttg tgacatatcc tttttggtca taaaattcaa tagctgtggc
    27181 acgatcacgc acgccttggt caaaaatcaa ataagctgat ttttcaggca atgctgtaat
    27241 tgctgcagat actttatccc ttgtatccat ttcattgaca aatcttttcc cctcttgatc
    27301 gaccaagatt gctccttctc cgcgaacaac ctcaccaatc aagaccccct catcctgctg
    27361 cacagttgga tgaatttgta ttttatccat atcaacggtt tgtccaccta atttttcaat
    27421 catggtgata ccatctccag ttgatccttc ttgatttgtc gtaatataat cagctaaatc
    27481 gggacgatat ttttcaataa attctttgct ggcaccaaaa ccgcctgtgg taactacgat
    27541 tgcttttccg gtgacctctt ttggttcttc tccttgaaca tgtacagtca cttcattgac
    27601 cgtttcccca tttttcttaa tgtctgtcac atctgcgttg acaaaaatag ggatttcccg
    27661 ctcatggacg ttattcaata acccctccac taagtatcca ccaatagccg agccatcaga
    27721 cggacgatgt gtcctctttt cactcatccc tccagtgatc gttaagttgt ccagtttgat
    27781 accgttttga tctagccaat cgaccgcatc agcagagtga tcgacaaagt atcgaagcat
    27841 ttctttatca ttcgttcctc caccaccttt tagcgtttct tcatagaagg catcattcga
    27901 gtctttgatt ccttcttctt tttgaaattt tgtttctgaa gcattcatac cgcttgatga
    27961 tttagatgtg tttcctccgg caacaggcat cttttccaaa attactggat tcaacccagc
    28021 atcttttgct tcgatagctg ctgccatccc tgcaccacca gctccaataa tcacgacatc
    28081 ataagattct ttcatttctt ttggatctgt atatacttgt tcagaagcgc ctgatgatac
    28141 ttcggcagat tccttcgtac tagaacttgt ctgcgctgta tttttctgat ctgcgccgca
    28201 tgcgctcata gcaagaagtg caacggctgt taataaacca gcaactaatt ttttcatttg
    28261 tatccccctt ttctccttat actatattaa gtgatttttt tcacaatatc aactctgttt
    28321 ttctttaagt catatagctt tggtaaacac acgcttctta gtataattaa ggatatacat
    28381 gaaggagtta ttttatgaat catttgaaaa ccttttttac gaacagtaca aaaactgcag
    28441 gtagaatcac aaacggaatc tatattttat tacgtatcat cgtcgttatt atgctagtgg
    28501 atcaggtctg gaaccaacac tggggaaata caatgctttt attactgaca ttaattttat
    28561 ttgaaatccc ttattttctg gaaaagatat taaagataca gattccaaat atgctagaaa
    28621 tcattttgtt atcttttatt tttagttcaa cagttttagg agagttaagt gatttttatg
    28681 gctatttttc aatgtgggat acttttctac atgcattcag cggattttta gctgggggtg
    28741 tcggcttttc ccttgtttat ttgctcaata aaaatacaaa aaccatgaac ttgactcctt
    28801 tattactagc agttgtttcc ttctgttttt cgatgacagt tggtgttatg tgggagtttg
    28861 tggaattttc agcagataaa ttactgcaat tcgatatgca aaaagatacg atcatccagc
    28921 aaatcaatag tgtggagtta agtaaagacg gaaacactgt ctatcatgtt ccagatatca
    28981 ctcggacaat cattgaaagt caaaatgcag atggtaaaac agataaaaca atcatccaaa
    29041 atggttactt agacgtggga atcatggata ctatgaagga tttatttgtt aattttattg
    29101 gagcagttgt tttcagtgta tttggttacc tctatagtcg aaacgattac caaaaattta
    29161 cgttcatcaa gaattttatt cctaaaaaaa tcaaacgata aaacatgcta aaaaacaaga
    29221 gaaggggcag tgacaatact tttgtcactg ccccttcttt tttgaatgta tggcatgcca
    29281 ttagttatcc gatagtatta actcaaaaaa gtaagatatg aggaatgact atttcgtttt
    29341 ttatcccaat actgaggact tatttcacca tttcgttatt tatctaattt acttaaaacc
    29401 tgcataactt tttcataatc tggattaggt gtgccgtcta gattttcagc aataaaagta
    29461 aaacccattt ttttataaag agcaatcgcc tgatggctcc atgtctgtgt gtgaagatag
    29521 attggtccgt ccgtatggag ggtaggaaat tcttgcaaga ctctggcagt caatgctttt
    29581 gcgagccctt ttccttggta atctggtttc actgctaacc aatgaaaaac cggatacact
    29641 tgctctcttg atttttttcg ccaagcggta caggttgcta ctttttctcc tttttttgtc
    29701 tctacaaaaa acatccttct ttcaagttct tcaggataag gagcaaagtt ttgttgaaaa
    29761 tactcaagtg cttcatctgt cgtttgaaat tccccaacgg aagtctcaat ctccgcccaa
    29821 gcagattcat cttctttttg ataaaatcga aattcaaaac cttccgctaa aggcgtgatt
    29881 ggaacatttt gttgaagtgg tcttgtcatc cagatttctg cgtaaggtaa cgttttatct
    29941 aacatttttc tatccctcct cgtctccatt atgccaaata acatatgact cagctactta
    30001 tttgactata acagatagag atataaatca gaaccagtca tctgcgtcaa attcatttcg
    30061 attagcgtat acccatgttc ctgccatacc tcgcatgaaa tctcctaaag cagaagaagg
    30121 aatacctcca ccaggtgcgg gtgttcccgg actaggaagt ggtacttgcg gctgcagatg
    30181 ctcatcggtg gaatcaatag ttgacaagcg ttttttcttc gtttccttct ggtcatctga
    30241 ttccttctga tcttccgact gtttagcaac aaattctttt tctgattgtt gttttatttt
    30301 aggctctaaa atttcatttt ccaatccaga aacttgtggg gccaaatgag cttcttgcct
    30361 tatcgtttta ttagattctg agatttttct agatattctt gctaactcta ggcttcttgt
    30421 ttgttttact ttccctgttg gagaaactgc atgagccatt tgttgttttt tttctgacaa
    30481 gctttcttct tgtctttttt gttctttttg atctatctgt ttgtttaatg gtaaaacatg
    30541 taatagtgac tgagcatgga gttcttggag tgaatacggg tcatgataac tatacataat
    30601 cgtaaaatca cctgtttgtt tggtcaaata accatcctcc aatggtactt cattgattgt
    30661 aaccgataca tcctttaacg gtacgggttt acctaaggaa tttgttgctg attggatcaa
    30721 ctcttctttg tttatttttt cgtttggatg aacaataaga tcatgacctt ctaatgaacg
    30781 attgtctggt atataaacat aagtaaaggt aatttcccct cctgattgct tcctattatt
    30841 catcagttct gagtgaagta cttcaaggat ctccgaccag tgactttttc tgtctaatcc
    30901 gtttgcttgc atccaatcag aaatagaagt gactttccca ttttgttcat aagtcgataa
    30961 atctatattt ggcactcgat cagaaaattc agcaggtagg cgcaaatcag gaatacgatt
    31021 tacactactc atatgtgttt ctgcttgaag ttctttattt gtttgactat ctataaaatg
    31081 agtgatgaca gtcgatgaag cagcagatgc ttctacataa actacagctg ttgtttctgc
    31141 cacatttgat gttttcgagt ctatataagt taatacaacg ggatattctc ccggagttgt
    31201 agtatctact gtcccgttca ttttgatttc ttctttattt cctgaagttc catcgctttt
    31261 tgttacatat tcaacaagat ctttaggggc gtaactctct cctgttctta agtgaagatc
    31321 ttttcctttg atagctgttt gatcacgaac atggatcaca gcagatgcag tcattgtttt
    31381 taaagcaatt ggatcaaaat aggacaagga aatagtagat gttcctgtat tagtcgtatc
    31441 cacgatattc ccattgtttg aaattacttt ggacatatct ccttgtgttc catctgcgtt
    31501 cttcagcctt tctaccagat cagatatcga aacttttgtc cctgccagaa catcgatttt
    31561 ctttctttca aactgtgaat aatctttttc atatacataa gaaacttgtg cgcttccacc
    31621 gtcctttata tctgtcaaag catgattcaa aatatcagtg atctgtttta actgatcacc
    31681 ttttgtagga tcagtcatat cggaaaagat agaaagcggc acactgcttc cggtttccga
    31741 tgtccataat gttttgttag gaattaacca gtagtggttt atcgttggag gataactgac
    31801 tttattatag gaagtcaatg caggaagtag ctgttttcca tttgcatcag tgaaagtatg
    31861 agtaatagtg ataggggaat cagtggtctc agaaacagag gtacgtacga ccttgatggt
    31921 ttgtgtcgtt gcctgaacgg gtacatgcat atagacacct acagataaac tgatcagcat
    31981 cgtgcgcatc ataaacttaa cgtagtgttt ttcagaacac gaccgttcct tatctaaacg
    32041 acaagcgtgt ttatttagtt gttttgaacg tctttttgaa cacatttatt cttagtcctc
    32101 cctactcttg tctaaacatg aagtagtaat tttcataaga tgatttcatt atataaataa
    32161 aatcaaaaga agatggacta ttaggagagt attttttttg attttttatt gtttcaagaa
    32221 aatcggaata ataacttatg tactttttaa ttttgttaag taatatatct agttatatct
    32281 agttatatct agttaccttt tctttgaaaa aaacataaat cagctaataa atatgtgaga
    32341 caaagctgcc atccataaat actagctgat tttttcagtt aaatgtctat ttttttctct
    32401 gatgatggta tttccaaaat attcccagtc atctggagtc ggtggatttt tccaaattat
    32461 ctgttcttta ttaaattttt caagtaaaca atcagataaa taaatattcg tacgagaagt
    32521 gattcgactc tcaatcacaa tattgtaatt tttaaatcct ttcacttgag aaataatgta
    32581 atcggtataa gcagatcctt gcgaaaaatc aatacagaca tgaatcggtg cttcaaaata
    32641 tgataccgga caaataccga ccaataaaaa gagataatca taaaataagc gaatcatgaa
    32701 acgttcatct tttcccaaga aatagcgttt attctcttgt atgacctttt ggattgctgt
    32761 actgaatatt ggatacgtct cgaagaaaaa ctgtagctgc tttttagacg taaagctagt
    32821 catctcaaag tcgaatatcc aattttttcg attgacatgc atcataccca tacgaagttc
    32881 ttttcgtata tatagtcttt cttcttcaga gatttcaatc gaaaatggta attgatcaat
    32941 caattccact gacatttttt gactaatcat gtggatatca tgaaaatgag cttccgcaag
    33001 tccaaatgcg ccatctaatt caaattcttc ttccgtgatc aaaaacaaca tgatataaga
    33061 aatctcatca atgatctgct ctttagggat atgaagaaaa gaaatatgtg ataaatcctt
    33121 gatgatcttc attccttctg agctcttaaa gtattcatct gaaaagaaac gttttccgat
    33181 tggttgattc ccataggccc tcaacaaact aatagtggtt agcaaattga atttgattcg
    33241 ttttgttgca gacagtttta aattgaacag atattcaaaa tattgcacga tactctttgc
    33301 ttcattcatg acgctttctc taaatggcat agaaaaacca ttaaagaccc cgaaatatac
    33361 cccaaataat acgttccgta tgtttatttc ttccccaact aatatgtttt tctttaactt
    33421 tatttgatgc tgttcaagaa aagagactaa ttctcttctt tttacatagg ctcttgatat
    33481 gcttaaaaaa tgattctctg caaatttttc gatcgttact tttgaatcca cgatctccgt
    33541 taacagtcga gcaatttttg atcgttgaaa gtagattctt cttaaatttt tgatatccgt
    33601 caaattcaga cgttcgacat ggatctctgc ttcttctgaa atttggatct ctggctttgt
    33661 tttgaattca gtaaattctt tatttaattc tatgatataa tttcttgttt taaatttaga
    33721 caaacctaat gtttcatata acttaggcag cactacataa ttctttttct caaattctaa
    33781 atatctagct agcagcagtt tttctctatc ttcctcttct ataaggtaat ccaacttcat
    33841 atcctacacc tcaaaaaatg cctcatacca attacttgat atgcagatga aagttcatct
    33901 tttcacctat actgatttta tgatggatta tgcttgtttt ttcatcagtt attctcattt
    33961 tttatctttt ttttgagaat attgcaaaaa atggaaaaat ttatgaggaa atattctata
    34021 ttttttgttt tattgtgtta aaatgtacaa gatttgcgcc atttgcgtaa acaaccacaa
    34081 aaaagagcag gacggccacc gtcctgctct tttacttatt ttaagttcca ttacttatta
    34141 attggctaaa cttctgcttg tttctgatat tgcttgtttt tctccaatga tccgcacttc
    34201 tgtttctaaa gacacatcaa atttttcttt gattacttct tggatgtgcg caatcaattc
    34261 aatataatct gtcgctgtcg catgatcgat attgacgatg aatccagcat gtttttcaga
    34321 gacttgtgca ccgccccatt tcaggccttg caatcctgct tgttggatca gctgacctgt
    34381 atagtgtcct actgggcgct taaagacact tccgcatgaa gggtattcta atggctgttt
    34441 tgattgacgc aattcggtca actcatccat tcttgctttg attgcttcat aatcccctgt
    34501 ttgcaaactg aatcgagctt ccaatacgat agcacgtaat tcttggactt tactgtgacg
    34561 ataagaaaat accatttcgt cttttgtcaa agttttcaat gttccatctt caagcaaaag
    34621 atccacttca gcaaaaacat ctttgatctc tccgccatac gcacctgcat tcatataaac
    34681 cgctccaccg acacttcccg ggatgccgca agcaaattca aatccagtca atgattctgc
    34741 caaagctgca taagtcgtat caatcagtga ggcacctgct tccgcaatga ccatcgttcc
    34801 tttgacatga atctgtttca tttcagtcag catgatgact acaccgcgaa tcccgccatc
    34861 ttgaacgatc agattgcttg catttcctaa taccatccaa ggtatatcat ggattcggca
    34921 ataatcgatg atttgcttta cttcttcttg ttttttcggg aatgcaagga catcagctgg
    34981 tccacctgtt ttcgtaaacg tatagttcat caatggttca tcaaacaata tagtaatcgt
    35041 ggctaagctt tcaactattt cttctttatt cactgaggat tttcctttct tttctcaaac
    35101 gtcctcatta ttctatcacg cttaatacaa tcttgccagt cttgttcaaa gttgatgacg
    35161 gtagtgatct ttaagcactt cctcacataa ttcatgactt cttacaactt ctttttgttt
    35221 aagcaattct gtttccgatt tacctaaacg gatctgagaa aagaaggcct ctaccattgg
    35281 ctcaaacccg cgtttgacta gcgtgtttgt ccagtcgcca aattctttca ctttttttcc
    35341 atcagcatct tgaatgacaa gctgggtcag atcgtttact tcataagtac catttttact
    35401 tgttacttga tatttttcta tattagcgcc acttgctaaa tccatcgtta aaatagccgt
    35461 ttgattttgt gtttctaatt gtaaaatggc atattccaaa aattcctttg tttctcttat
    35521 ctggtatttt gttctcaaaa tgggttcatc taataaatac acagctgtat caataagatg
    35581 taaaaacaaa tcataaagga cgaactctgt cgtttctttt gccgctattc gatttttttg
    35641 caggtggatc aaccgcttat ctgggatacg tttcaattct tctaccatag gagcaaagcg
    35701 ccggttgaaa ccgatcatca aaattatttg gttcttatca gctaattctt gcaattcacg
    35761 aacttcattt agatggacac tcagtggttt gtcaatataa acatggatac cattttctag
    35821 acattttttg gctaattcat aatgtacttt tgttgctgcg tggatcatac atgcttcgat
    35881 tttttcttct aaaagctcat cgatcgtttc atatagatgt tggaacccgt actctttttg
    35941 aattctttct tttgtttctt tatttcttgt tgcaaaataa aaatcaagtg ttccttgttt
    36001 tttcgcataa gttggtaaat atgctttttc tgcgatattc cctacaccga ttacaccaat
    36061 cttcatctac tttcctcctg gatcatttag ttactttcat cttacaccat tttttactaa
    36121 aatgaggtac aatagtatcg caaaggtaag gaaattaatt cgaaggagtg tgcttttatt
    36181 gaaatttatc tcttggaacg taaacgggct tcgtgccatc gtaaataaaa attttttaga
    36241 agtttttcat gagttagacg ccgatttttt ctgtctgcag gaaacgaaac tccaagcagg
    36301 acaaattgat ttagatcttc caggttatta tcaatattgg aattacgcgg aacgaaaagg
    36361 ctattccggc acagcgattt ttgctaaaaa accagcattg aatgccactt acggaatggg
    36421 tatcgatatc catgatacag aaggccgtct gattactttg gaatattccg atttctttct
    36481 tgtaacctgt tacacgccaa attctcaaag cgaattaaaa cgtttagatt accgattaga
    36541 atgggaagaa gccttttata attatttgga aaatctaaaa aaacaaaaac cagtcatcgt
    36601 gtgtggggat ctaaatgtcg ctcatcaaaa gattgatttg aaaaactgga aaacgaatca
    36661 aaaaaatgct ggattcactc cagaagaaag agcggctctt tctcgactgt tggataacgg
    36721 gtttatcgat acattccgtt atttttatcc aacccaggaa ggtgtctact cttggtggaa
    36781 ctaccgattc aattcaagga aaaacaatgc tggttggcgg atcgattact ttttgacgag
    36841 caaagattta gagccaggac tagctgatgc aaagatccat acggacatta tgggcagtga
    36901 tcattgtcca gtagaattag atttgaaata aagaggttgt gaaaaagtcg tttagtttcg
    36961 agtattaaga aaaattttgt gaaaatggct ttccacattt tgcataaatt tggcataata
    37021 ccgagaaact ggcttttgaa cactgtttat cgagagattg tgaaaaagct gtcctgcatc
    37081 aagtaataag aacagccaaa caaaaatagt tcctcatatt
//
LOCUS       DAFBSV010000017        35881 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.017, whole genome shotgun sequence.
ACCESSION   DAFBSV010000017 DAFBSV010000000
VERSION     DAFBSV010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35881
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.017"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            79..1125
                     /locus_tag="LLB18_000843"
     CDS             79..1125
                     /locus_tag="LLB18_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBK5243862.1"
                     /translation="MTKPNHIESSKKEAPKTEGQTKTFSTPQQIESTESFQSQPILSG
                     NEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIAQAILESASGQSQLAQAPNY
                     NLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYENYEESFEDYAKLLTKGISGN
                     KDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNELIKTYDLTNYDKEVKGPQMS
                     KTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIHAVKAGKVVKAEFHYSWGNY
                     VVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGSTGNSTGPHLHLEICKDSSLS
                     QSMLVDPKTLLFGD"
     gene            1474..2106
                     /locus_tag="LLB18_000844"
     CDS             1474..2106
                     /locus_tag="LLB18_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HBK5243863.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            2694..4133
                     /locus_tag="LLB18_000845"
     CDS             2694..4133
                     /locus_tag="LLB18_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5243864.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            4428..4646
                     /locus_tag="LLB18_000846"
                     /pseudo
     CDS             4428..4646
                     /locus_tag="LLB18_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251366.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            4895..5110
                     /locus_tag="LLB18_000847"
     CDS             4895..5110
                     /locus_tag="LLB18_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243865.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(5327..5583)
                     /locus_tag="LLB18_000848"
                     /pseudo
     CDS             complement(5327..5583)
                     /locus_tag="LLB18_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5770..6681)
                     /locus_tag="LLB18_000849"
     CDS             complement(5770..6681)
                     /locus_tag="LLB18_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK5243866.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(6700..7704)
                     /locus_tag="LLB18_000850"
     CDS             complement(6700..7704)
                     /locus_tag="LLB18_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBK5243867.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(7701..9824)
                     /locus_tag="LLB18_000851"
     CDS             complement(7701..9824)
                     /locus_tag="LLB18_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBK5243868.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(9829..12276)
                     /locus_tag="LLB18_000852"
     CDS             complement(9829..12276)
                     /locus_tag="LLB18_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK5243869.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(12263..12652)
                     /locus_tag="LLB18_000853"
     CDS             complement(12263..12652)
                     /locus_tag="LLB18_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK5243870.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(12712..13215)
                     /locus_tag="LLB18_000854"
     CDS             complement(12712..13215)
                     /locus_tag="LLB18_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBK5243871.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(13228..13452)
                     /locus_tag="LLB18_000855"
     CDS             complement(13228..13452)
                     /locus_tag="LLB18_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243872.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLSLFNRIVGA"
     gene            complement(13556..15466)
                     /gene="ltrA"
                     /locus_tag="LLB18_000856"
     CDS             complement(13556..15466)
                     /gene="ltrA"
                     /locus_tag="LLB18_000856"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBK5243873.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            complement(16212..16349)
                     /locus_tag="LLB18_000857"
     CDS             complement(16212..16349)
                     /locus_tag="LLB18_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBK5243874.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            complement(16346..17530)
                     /locus_tag="LLB18_000858"
     CDS             complement(16346..17530)
                     /locus_tag="LLB18_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBK5243875.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            complement(17789..18079)
                     /locus_tag="LLB18_000859"
     CDS             complement(17789..18079)
                     /locus_tag="LLB18_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243876.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            complement(18069..19211)
                     /gene="dcm"
                     /locus_tag="LLB18_000860"
                     /pseudo
     CDS             complement(18069..19211)
                     /gene="dcm"
                     /locus_tag="LLB18_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            complement(19287..19451)
                     /locus_tag="LLB18_000861"
     CDS             complement(19287..19451)
                     /locus_tag="LLB18_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243877.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            complement(19444..20118)
                     /locus_tag="LLB18_000862"
     CDS             complement(19444..20118)
                     /locus_tag="LLB18_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBK5243878.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            complement(20196..21536)
                     /locus_tag="LLB18_000863"
     CDS             complement(20196..21536)
                     /locus_tag="LLB18_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBK5243879.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            complement(21619..21954)
                     /locus_tag="LLB18_000864"
     CDS             complement(21619..21954)
                     /locus_tag="LLB18_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HBK5243880.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            complement(21964..22338)
                     /locus_tag="LLB18_000865"
     CDS             complement(21964..22338)
                     /locus_tag="LLB18_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBK5243881.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            complement(22351..22665)
                     /locus_tag="LLB18_000866"
     CDS             complement(22351..22665)
                     /locus_tag="LLB18_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBK5243882.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(22778..26005)
                     /gene="fss3"
                     /locus_tag="LLB18_000867"
     CDS             complement(22778..26005)
                     /gene="fss3"
                     /locus_tag="LLB18_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBK5243883.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVALVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            complement(26419..27585)
                     /locus_tag="LLB18_000868"
     CDS             complement(26419..27585)
                     /locus_tag="LLB18_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBK5243884.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
     gene            27610..27936
                     /locus_tag="LLB18_000869"
     CDS             27610..27936
                     /locus_tag="LLB18_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243885.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDTGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            28089..29141
                     /locus_tag="LLB18_000870"
     CDS             28089..29141
                     /locus_tag="LLB18_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBK5243886.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDSSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            29217..29435
                     /locus_tag="LLB18_000871"
     CDS             29217..29435
                     /locus_tag="LLB18_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243887.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            29422..31995
                     /locus_tag="LLB18_000872"
     CDS             29422..31995
                     /locus_tag="LLB18_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243888.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKTVDVRENIQKDSGEMKEKTQKINIVEDRKSAKKF
                     DSNHETVIIDSEIRENDKGSKSRRRFTYEDNELFRDTLNDPNPLFDNLLRNKRGGLSC
                     N"
     gene            31986..32183
                     /locus_tag="LLB18_000873"
     CDS             31986..32183
                     /locus_tag="LLB18_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243889.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
     gene            32187..32798
                     /gene="mobC"
                     /locus_tag="LLB18_000874"
     CDS             32187..32798
                     /gene="mobC"
                     /locus_tag="LLB18_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBK5243890.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            32783..34174
                     /locus_tag="LLB18_000875"
     CDS             32783..34174
                     /locus_tag="LLB18_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBK5243891.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            34390..34704
                     /locus_tag="LLB18_000876"
     CDS             34390..34704
                     /locus_tag="LLB18_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243892.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGIFGSKANMFRVMVSNLP
                     VLASPSNNKFNDPESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            34697..35191
                     /locus_tag="LLB18_000877"
     CDS             34697..35191
                     /locus_tag="LLB18_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243893.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRPQQW
                     SIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
     gene            35259..35573
                     /locus_tag="LLB18_000878"
     CDS             35259..35573
                     /locus_tag="LLB18_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243894.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            35672..>35881
                     /locus_tag="LLB18_000879"
     CDS             35672..>35881
                     /locus_tag="LLB18_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBK5243895.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDL"
BASE COUNT        11188 a         6791 c         6364 g        11538 t
ORIGIN      
        1 tcaagtgaaa gtagtacgat ttcaagtacc gaatcttcaa caacttcaag tagtacaagt
       61 gaaataactt cttcgaaagt gacaaaacca aaccatatag aatcttcaaa aaaggaagcg
      121 ccaaaaacgg aaggacaaac aaaaactttt tcgacaccac agcaaataga atcaacagaa
      181 tctttccaat cacaaccaat actatctggt aatgaagaaa ttcattttga caaaaatgaa
      241 tctgtagaaa attttattat gaaaattggt gagtctgcga gaaaaattgg tcagaaatat
      301 gatttatatg cttctgttat gattgcacaa gcgatcttag aatctgccag tggtcaaagc
      361 cagttagctc aggcaccgaa ttacaattta tttgggataa aaggaactta taatggaaac
      421 tttgtcatta tggtaacaaa cgaagatttg ggtaatggaa cgctttatac gacccaatca
      481 aaatttagag tgtatgaaaa ctatgaggaa agctttgaag attatgccaa attattaact
      541 aagggaatta gtggaaataa agatttttat gcaggagcat taaaagctaa tagtaaaaca
      601 tatcgagaag caactaaatt ccttacagga cggtatgcaa cagatacaca atactatttg
      661 aagctaaatg aattaattaa aacctacgat ttaaccaact atgataaaga agttaaaggt
      721 ccacaaatga gtaagactgg ataccaagtg cctattcata attattcaat aaccagtttg
      781 tttggaaatc gtggaaatga atttcaccga ggacttgata tggcagctac acagggtgag
      841 ccgattcatg cagttaaagc tggtaaggtt gttaaagcag agtttcacta ctcttgggga
      901 aattacgtgg tgatacaaca cgaagatgga tcaaccgcgt tatatgctca ccagcaacaa
      961 tacctagtaa aaactggaga taatgttttg caaggacaaa taattggcta tgtaggaagt
     1021 actgggaata gtactggccc acaccttcat ttggaaattt gcaaagatag tagtctttct
     1081 cagagcatgt tagttgatcc gaaaacctta ttattcggag actaaaaaag gtaatcaatc
     1141 tgacaaagta acaagaaaat ggttggattc ttagaccttt gatcaggata ttgagactgg
     1201 aattgatatc tcgattacga tgggtttgac aaataaaaca agtccattat cgaatatcga
     1261 gtgtattatt gccgtcttta tgctcatatt ttgagcaggt ttcactagat gaaaacaatt
     1321 tatctatctt gaggatttcg tgtacgtatc gttcagtctt gtattgtaaa ttagtcataa
     1381 aatcagacta agaaaaattg gaaatatttt tttctgattt attaaaagtt aattgaaatt
     1441 atatggtact tctttcttgg gagggtaggt gcagtgaagg aaagatatgg tcaccttact
     1501 gttgttgagg agattactca taatggatat aaaaaatatc gttgcctatg tgactgtggg
     1561 aatgaaacga ttgtatatcg atcaaactta ctatcaggta gaaccaaaag ttgtggatgt
     1621 ggaaattata aaaataggca taaatataaa aatttgacaa ataaaacttt tggtaagtta
     1681 gttgcaatca agccaactaa actgcgaagt gaaggaactg ttgtttggga atgtcaatgt
     1741 ctgtgtggga gaaaaaagtt agtatcggca aagcgacttc taaaaggtga tgtaaaaagc
     1801 tgtggatgtt tgaaatcaaa aaagcatcac attgaaaata aaaaattcgg attacttact
     1861 gcaaagtatc ctttggacaa taactgttca tggaaaacaa aatgggtttg tcattgtgag
     1921 tgtggcagta tgtgtgagat aagttatagt aacttatttt ttggacatac tcaaagttgt
     1981 ggatgtttaa aaaggcaaga aacaaggaca tgtgttgaag ggacagtaat agagtgtcta
     2041 acgtcaaaat taccgaaaaa taatacaagt ggtgttaagg gagtttatcg ttctaaagag
     2101 aaatagattg cgtatataac tttaaaaaaa aagaggtact atttaggatc gtatgattct
     2161 attaagagtg cagctcaagc tagaaaagat gctgaaaata aattgtttca acctttgatt
     2221 gacaaatatc gaggtaatca ttaattattg tggataataa ttaacagtga tatataaaca
     2281 tctataatat attattcata ctattgatat ttagtataat cctatggaat tgaatatcat
     2341 agcaatgtat ttgaaaagca aattggaaaa caaataggtg caacaccata aatatgaaaa
     2401 aattgggaaa aagtagaatg gaaatttgct tacgtctcac gagatagctc acactattaa
     2461 tctgaagaac aatgaagtcg acttttagaa attgctagaa gaaagtaaag cgaattatca
     2521 ctagttacta tagagtaagt tcaaataaag catctccaac ttacatggtt acatgaggat
     2581 atcaaatcga aattactcaa gcttcctatg gctagagtcg cgagaagttg ttgggcagta
     2641 gacataggtt atattgttct tagctacacg atcattagaa aggaaatcct attatgtata
     2701 gttatcaaga agatgcaaaa gtccaaaaaa atcgctggtg gattttgatt gctatatcta
     2761 tgtttacctt catgtccaca ttggatggca gtattgtcaa tattgcacta cctaccatct
     2821 cagatgatat gggcatacca atgaatcaag cggaatgggt agtgtccgtt tatctgatga
     2881 ttgtctgttc ttgtttgttg ctgtttggta aaattggcga tagccgtggg aaaatcaaag
     2941 tatttcggat tggtacgctg atctttgtct tgggatcgct gttgtgtggg ttcaatcatt
     3001 cgctaggtat tttattgttc gcacgggtgg tacaagccat tggtgctagt atgactatgg
     3061 ctacaaatgc cggaatcatc acggaagtct ttcccataca tgaacgtggt cgggcattgg
     3121 gagcaatagg tgcgtttgtt tcattaggct cgattgctgg accaggtctt ggcggcttga
     3181 ttttgtccca attttcttgg gcgtacattt tttggatcaa tgtaccggtg ggaatcgtaa
     3241 cgatgttgat tgctgaaaaa ttcttaccaa aagatatcac catgagcggc catacaatcg
     3301 atggaggggg ctttgctgcc attgcggcta cgattatcag cttttttgga gcaatctttt
     3361 tggggcaaga aagtggcttt ttccatccag tcccccttgt actgttcgta atttcagtga
     3421 ttgcctttgt cagcttttta aaagttgaaa agaaagcagc ctctccattg atttctttcg
     3481 gtatttttaa gaacaagatt tttaccatga gcttgattac agccttgttg attttttctt
     3541 ccaacttctt tgtcaatgta gtgattcctt tttatctgca aaatgctcgc gggttgagtc
     3601 ctagctatgc tgggctgttg atgatggtct ttcctttgat gatggtcgtc ggggcgcctt
     3661 taagcggcta cctgaccgac cgggttggcc cggagatttt ggtattagta ggcttgggct
     3721 tattgtcggt aacccaggtc atgtatatgt ttttgtcagt ggactctcct ttgtggctat
     3781 acattgtcgc tactgccatc atgggtgccg gcaatgcctt gttccagtcc cccaataata
     3841 cgatggttat gagctcggtc actatcgaaa acttgggact ggcaggctcg atgaattcct
     3901 ttgcccgaaa tttggggatg gtcagcggga tttcgctttc tacgacggtc ttatatcaag
     3961 cgatgtctgc taagatgggc cagcaagtaa ctaactatat cgcaaatcgg ccggatgtct
     4021 ttttatatgg aatgaagatt acctttttag gcagctttgt tttgtgtttt gttgcctttt
     4081 tcctgactat ctggcgtatc aaaaaacaag gaggtattca gaaaaatgtc tgaaaaaacc
     4141 actgttgaag aatttttgga ggcctgcgta tgggtgagtg ggatttccat ggatgatgga
     4201 agatgaagtg aacttctaaa agccgaaaaa ctcaagtatt atcttcaaaa tactagtgct
     4261 caatgagatg cttgatttga tcacaagaag actgcgaaag ccgctggcaa ccgcaagcta
     4321 ggtatcccac cgatggacta cgttttagag gctactggtt atgaatacgg agccaacgct
     4381 ctcatctgca taagaataca tcacccagat tatgtaaaga ttttcgatac ttctgtcaaa
     4441 aaatcattaa gatagataaa tgatttccgt ctagtcaaat tggttcagaa tgtagacaca
     4501 cagatggtaa gaagtcactc acaattcgag aatggacttg tcctatttgc cgtatacatc
     4561 ataatcgaaa cgtcaacgat agtatcaata ttttgaccaa gggctatgaa tacaagcatt
     4621 gccttagaaa acatcaagaa ccttaggaac aacggggata gcttggttaa taagagatac
     4681 cgctgtttag gcttgcaagt atactctttt atcaagaatt ccgtggcttt agtcatgaga
     4741 ggcttaatac tatgaaaatt ttctttagca tttttgattt aggttccttt tctaattata
     4801 ataagatgac cactacagta acctactgaa atatataaac agccactgta gtaccatttt
     4861 caaagtagtc tatgagagga gaatcttcat tcttatgaac gctggaattg cggatatgaa
     4921 tttaataaaa aaaaccctta atgattttac ttccaattca atatcaaaag gtactggtat
     4981 caatttaagc acaataaaaa agctgaaaag tggtgaaaga tcagtggaaa agctgaatct
     5041 tttagatgct ataaaaataa cggaatttgc tatgaaaaat ggaaaagctg agattgaaat
     5101 atggagataa ttatcgtcta gtgaattact tgccacttag ctgaatttaa cgatccttgg
     5161 tgcttgaagg gggagattct tgggaataga gcatacttgc aagcctatgt ctttactaac
     5221 aacgatatct cttattaacc aagctatccc cgtagttcta aggcttttac ttttatctaa
     5281 gcaataatcg tattcaaagg aaatttttga cccttagaaa gtctcatttt atcagacgtg
     5341 agcttaggca ttgctgaatt ttgttaattc ggttttaggt tgtgctttga gcataatatg
     5401 aaagtattct ttatcacgat ttcattcatc taaggtaatg tgatgtgatt ctgaaattct
     5461 ttcaaaggca gtttttgcat aagctgacat tacatcatca atgacatgtt tacaatgttt
     5521 cactactaaa ataagggggt aaccaagaag aaaaactgaa tgattatttg tatctaattc
     5581 catggtatat caaccatttc ctatatagac tgattatgac atggattaaa ataaaaaggc
     5641 actatgtctt aattgtcggt tttcgagtta ccgaatggca ttcatcaccc acctatagag
     5701 gatgggcgac ttctgcctga aataagttac actacttata acttctaata aaattagatt
     5761 gagtcattat tatttaacat caacgatttt ccagtttcca tttttttgta atactaattt
     5821 gtactgaaag tagctagtgg tttttgatac attatcaagg tattttatct ttgtactcac
     5881 tagaaaattt tttccgtttt gtagataaac tggattctct aactccgaaa actttaagtc
     5941 aatattgatt ggtcgcatcg caccattttc aacataatac tccaattctt tttcagaagc
     6001 tgatggataa agtttaaaaa atgtttctaa aaaatcggtg atttcttccg ttgttttggc
     6061 atcaatttct gaatcgtttt ctacttgttt tgcttcatat tttgccttgt ctggctttcc
     6121 aatcattgtt ggcaaactag ttactaaatg attcctgttt tcatcttcaa agattgtcac
     6181 tcgatatgca gaagaaattg attgcgtctt ttttccctct gtaatatgtt gctccactaa
     6241 aaatgaaacg acaaattctt ccgagtgttt ttcaacatct agaattttta cagattgaac
     6301 ttcggaactc gtgggaatat ctgctcgaac catatcttgg attaaagcga gaccgttttc
     6361 tgtaaggtac tgttcgagat tactcattct cttttcaatt gcttctttgt tatttttcca
     6421 tgaaaaatat tctttcgcaa aatcctctgt aaaactttca acgccagaag tattcactac
     6481 cttctctttt ataaccactt tttcatgagt tgtatgttga tcaatggcgg tgaaattttt
     6541 ataaacgcca aaagcaagac tacaagacaa taaaagccaa agggcaagca ccatttttcg
     6601 atgcttaccc acggatacaa ctcgttcttt tttctttttt gggctctttt ccttttgatt
     6661 ccgttcaatt tttatcttca ttctttttcc tcttttctct tatttgtatc ggccagctcc
     6721 gataagatgc tgccgccaat agttttccgt tagattcgtc caccccactg gatctcctgc
     6781 atgaaacatg cgattctccc ctgcgtaaat gcccacatgg gtcacataag taccggcatc
     6841 ataggttgaa tgaaagaaaa ctaaatcacc tggtttggca tcttttagat caatatgagt
     6901 catggcatca tattgatcct gagccacccg aggaagtttc aggtcaactt tggcataaca
     6961 ccattgggtc aagccactac aatcaaaccc cgtttctgga cttgagccac caaacacata
     7021 ggccgttcct tcatacttaa atgcctcatc aaaaatttct tggactattt tgtcatcaaa
     7081 ctgagttgta gttaggtatt gcttcactaa taaacagtaa aacatattgc cataattata
     7141 ccgccaccca ccattttcct taatcgcgat tgggttgggg taatcgactt tttgaccacc
     7201 tgatttttcc tttgaaaaag attcagctaa agcaaaacta tgcttcttcc cgtttttccc
     7261 gacatgatct agatacccgc caccatagtt ataggcctga ataatactat cttgatcaca
     7321 ccctagttct ttggaacgct taaccaaaga cgcaaaatag agacagcctt gtttgatgga
     7381 tgcctcggta cttaatgaat taggtggtaa tccggctgac tcagaacttt gcataacgtc
     7441 ttccattgtg ccaccagatt ccacttgaat aatcgccaaa agaattggaa tatactctgt
     7501 tatatccgat tctttggcat acttttccac cattgcacgg tgtttcaata cttcttctga
     7561 gacactagtt ccgccaggag aagtgccaga actaccattt ccctcactgt cttcaccaaa
     7621 caacaaaccc acacacatca aaatacccat aaaagagatg gtcagaaaag ttaatgaaat
     7681 aacacccact ttcttcaagt tcattttttc tcacctgacc ttgattttgg acgatggttc
     7741 attctttttt gtactttttg attggtctgc tttggcagag tggacctctg tttcacttgt
     7801 tggaaagaat ttttcttact tgctgattgg cttttccctt ttgaaatgat ttcttgacta
     7861 gttagttttc gtttgatttc gggattcaga tttgctctca caatccgctt tggtgcttct
     7921 tttttcagca tcatatcttt ctgaggttga gctgctttat ctattggaat attcgccctt
     7981 ctttttccct gacgatttgt tgcttcactc agtatcttgc gtttttcgtc cattttcgca
     8041 tttcttcgtt gtcgttgttt ttctcgcaaa tccactcgat ccgctttttc ttggaacagt
     8101 ccgcgcttga attcttctgg tgcttttttc gacttttcga ttcctttatg gagattgtat
     8161 ttcaaattcg ttggcgtatt ccttacctga tcctttactt gtttagtctt atctttcacc
     8221 aaagcttggg tatccaaaac tttgccgatt tttctcccag ccaaattcat tcgggattgt
     8281 ttcttattat ttgaaactgg attctcctta gttaagtcag atagtatttc gtgatcgttc
     8341 ggtaatcgtg aattctttcg tagagaagaa ccggatggct taaatttgga ttttgattgt
     8401 tcctttgcca acttatttcc gactgctgca ccaccaccaa aagccaaagc tcgtcccaca
     8461 tttcgattga gttgccgcaa ttttcgattc attaacattt gcggttttcg catgacgcgt
     8521 cttcccattg actggctatc attactctgg aggttgaaca tactcataat gtcgcccaat
     8581 ttgaaataga taccggcaaa ggtcacaatt tgcagaaaag caaccatgaa aaatggatag
     8641 gttgccgaaa tattgaaaaa catcgtggag atgctaaatg cagtcgtaat caccaaagta
     8701 acacccgctc gcatcataat cgtattgaat aaacgaataa tcgccttctt tcctaaactt
     8761 tcataagtcg gcaacatgga caataagaaa ctaattggca gaaacatcgc aaagataatg
     8821 aagagaattt gcgagaacaa cataatccct gttagaagaa aaacaaagaa ggaaatgcca
     8881 atattgaaca ataccaaaaa gaccacggtc cctaaacggt tcatggtctt ggtaatactg
     8941 agattcgcat tgtcattgtc ttcaatctct gccttgaccg cttcttcccg atctttgcct
     9001 ttgttttcat ctggactcac agatagaatc ttgttgaccc ggtcttcacc aatttcttct
     9061 atgttggaat catcaaattg cagtagtaac caaggttgtt ggacttgaat cgaaaacaaa
     9121 ctatcccgaa tcaaatccac actatctttt ccttggcttt ctgaattggg tacaacgatc
     9181 tcggttccaa gggtaagggc cgcttcacta acatctgagc taaagtcatt gatttttgtg
     9241 atataggtag gcgcataagc aatgaacgaa cccgatagta gaaaaatcat cacaaaatta
     9301 atcacggctc gaactgcttt cgtggtttct cgttttaata atccggtata cgccacatac
     9361 acccccagag ctaaaatcat caataataga aacccaaaat aaaatccgga ggtctggagt
     9421 ccattttcag taataccagc caatgtttgg atattctttc caatactttc agccgtatcc
     9481 gaaatgaaat ctaatttgta agcctcttga accacataac ccgtggcgtt cgacaaatac
     9541 aaactcaccg tccaaatgaa attagtaatg gcataaagac catacatcac gcttttccct
     9601 aagccatcac cccaattcca aggcaaccaa tcccaagagc tatccacaaa gaaatctagt
     9661 tgatagttgt tcagtgaata tttggaatat agatttcctg cttcaactgt atcatcaact
     9721 agccctgtcg cctcggctac cgtaccaact aaactcaata gaactatcag agtgagtatg
     9781 ctaataaaaa cgattcccac aatccgaaaa agtttctttt tcatcccctc actccattct
     9841 ctcttgaaca ggtggacggg tatcaaaggc atggaagagt tcttcaaaga ctggatgtac
     9901 ctgaaccacg cctacccgac catacaaatc ctgcatcaag cattggccat tttccaaatc
     9961 tcgtaggcgt ttttgattgc tttcatcttc tcgatccaag ccaaagaatt ccaaggtttt
    10021 cttgatttca tgaatatcgg tactgcgaaa cgcaaacttc aacccgatat tattcttcaa
    10081 gcgttcatcc agtaaatcat cactattttg cgtgacaaag taaaccccgg cattcatagc
    10141 ccgcccagca cgaacgagct tattcgataa tgttttccct tgcgctactt gaagaaaact
    10201 ccacgcctca tctaagtcta caattttgaa gatttctcga ttactatgga taaagtccaa
    10261 ggcaaaagtg gaaatgacga ttagcatgga aacactaagc aattccatgg tggtatattc
    10321 ttcaaaagtg gtttctgcat ctggtaaaac caaatccgct acttgaatga tatttaactg
    10381 cctatctaaa ctaatcgact gggtaatcga accatctgag aaaagcaaat gggcaaaatc
    10441 ataatcggta aaggactcga tgtgatccgc gatattttcc gcaactggtg agccttcttt
    10501 tcgaagctca ttaattactt gtaataatcc ccgttgattg ctttgggtaa ccgtccgaat
    10561 ggccttacgc aacactggaa acttctcccc atctcgacta gaaattcctg ttaaaaaggt
    10621 cagaatatca attgctagac tttcagaatc cttctttttc tccataatca cataaggatc
    10681 aagtaatcct tgattttttg gcttactagt taagttgaga atattgattt catccgcaat
    10741 ttctggcaag gtttctttcc agccaccccg ttcccctttt ggatcgacaa tcacagcttg
    10801 tccaccaaaa aggacggcgt aataaactaa gagattgtta ctaaaggact ttccgccacc
    10861 gagtgaaccg aggaatgccg ctgctagcgc attggtaact gaacccttga ccccttgtga
    10921 ggccaatgcc ggtttcaggt aaacattgcg ccccgtatct acgttataac caaagtaaat
    10981 gccttccaac tcccctaaca tctgagtggc gccaaaacca agtccggcga gaaaatcaga
    11041 cgtaacatac tggatataat cattcatgta tcgcttacta gaaggtaaga attcttcatg
    11101 tagccccatc atatcgccaa aaggccggac tagttttaca ttggtatcat cataaaaatc
    11161 tagcacttca tcacaccggc gctttagttc atctactgat tcggcactta ctcgaaccac
    11221 atagctcagt ttgtacatgg attctttgga ctgatccaag gtagtttcca attcatctac
    11281 ggaatccaat gcatctaaga cattggaatt tgtttcattg tcagattgat aggcatggtt
    11341 gtccaagtct tttaattcct ttttcttatt gcgaacggta gcaagtgcct ttttgttcgt
    11401 cacaatctcc acattcatac tagtgtcaat tgggaatgta aattgttgtt gctggtaata
    11461 gaaaagttct gaggagggaa actccatttc ccccacaatt gtattaattg ttaagtacgc
    11521 tacatatgat tcatgattct catgttccat gcataagtac cggggctttt cttcaatcaa
    11581 acaacgactg ggacgtaata agtcgtaacg tttcaccaaa gtttccgact tcagcttttt
    11641 ctttggtagc tgaaattcat attcttcaaa tggtgtaccc ttttcgccat agatatgttc
    11701 aatcaaatac atcagatcac tcggtgtgac tcgtctgact ttaaatcttc gagccaattt
    11761 actttccatt agtttttcaa gcttggtata tcggcgaatt tcttcattgg ataaggaaac
    11821 aaaatcgccc atcaaatgat gattcactcc atagacaaat tcttgaaagc cggagaagaa
    11881 agatttcttg agattcttta gattgacctc ttcatctgtc gcaatcagtt tgaagccaat
    11941 aaaaaagcga taatcaatct gactatcgcc aatcatggat actaatgcct ctgtctgtaa
    12001 atcaattcgt tgtttcgcta cttctgttaa tcgcccggta atttcctttt ttgatcgttc
    12061 ttgcgtggca cgaatactac tttctgtggc aatttgtaag gcatgaatct tgccttcacg
    12121 attttgcgca atcaattgac gaaagttatc gtggacttga tatttctgtt caggtgacaa
    12181 aaaggagtaa ttgtaaggta ttaactcata gtaggcaaaa cattctccct cttgattaaa
    12241 gacaagatta ttttcaatat acttaatcgg gtacatagtt cacactcctt accagagtaa
    12301 tgggttcgtc ccatcgtttc ttctgttctt tgactttctt tcctgcgaaa gtgaccttaa
    12361 atcgtaagtg atagctaata aaagatcgta aaaatcccaa tggtttctta ccgtcaaacg
    12421 ttttttgcga catgaaccaa gtaactgcca ccggtatacc taagtatttt aaaaaggccc
    12481 cctctatcat agatagtgga ggcacatggg caaatacgat gacaaacagc aaggataaaa
    12541 caaaccaagc catctggtta aaagtcacag gaaaaggcag ttgaaagtca ttaattgcat
    12601 aaatgacctt ttcaactgcc caaatactgg tgtagctttt tattttcttc atcaaatcat
    12661 tcctttaaaa agaaggatag tttagaaatc aactaccctt caataatttt gttaatatgg
    12721 atactcaaaa acacctcgac tcgttaccaa ataattgcct ccaatctcca agtctctacc
    12781 acacgcatca aaatcaatat acgtcttcaa gtgttctggt acttctccaa aatcaccagc
    12841 ttctacaatc aagaaatatg ctacatcact catatcatcg caatctggat aatagataat
    12901 atcatccaca tgctctacca tctcctcaaa agaattgaag aaagcatgtt gaatctcaga
    12961 agcaacttca ccaactggcg ttccttcaag ttcctccgct aagccacaca accgattaat
    13021 ttcctcaatt ggcgtatact catcaatctc aaagggaagt tcataatcat gaattgcata
    13081 ttcctcgtat tcgtcattta acccaattcg ttctttcact tcatcaaaat cgacaggtgg
    13141 ggtaaaccac gcccccacca attcaccttc gttatatttc ccgaggttcg caatataaac
    13201 acgcatctgt tccatcgtgc ttccccctta cgcaccgaca attcggttaa acaaactgag
    13261 taagacatcc ttcaccccag aagcattaaa gaccaatccg accgcaatca aagcaatcac
    13321 caaaaagcca atcagtttgg aaaactcccg cttaaatcct aaaaacaaac caatgaccac
    13381 aattgccagt aagactaagg attgggcatt ggttaaaaac cattgatata tggataggta
    13441 agttcctgat attataaata tctcaaactt ttccccccat tcacacggag cgtgcgactt
    13501 tcaccgcact ccgcgttcca tcgtgtttat attgaaaagt atttatgtag tagacctata
    13561 tcaagtttaa ttcttgattg ccagctaata ctctatattt atttagtctt atgagctgga
    13621 ctttatttag cttcaataga gctatatatt tttgtattgt ttcttctgtt ttagcgtgta
    13681 ttagacggtg taccgcctct tttaccaaaa taagattttt ataatcgtca tttccaccag
    13741 ctccagttgg tacaatatga tgacaatgta tttcattagc ttgttgaaat tcttccagag
    13801 ttatagcaca ttttccatgt tgagcagaaa atagcgaaat tcgattgtct gcgtattcta
    13861 ttgtgcgatt ttccaaagat aatttcatta actggtacat cagtaattta tcaacactta
    13921 gattggtgtg gataaatttt cttccctcta gagtgtagca attcgctaaa tacacctttg
    13981 ccattggttt tctgtgttgg atatatccaa cagggaaaat aggttcgccc tcgccagcaa
    14041 cataccgaag cattttagat ttaccatatc ttgttgcctc ctttgtcgta agttgtctgc
    14101 ctgtttttct caatctgccc cttttgtttg tacctaatct gttagtgaag atagccatta
    14161 cagctctatt cagtttcata caatccagat ttacattcgt tgcaatctga taataatttt
    14221 gcatacctaa taccattgaa ttataaagtc ttgtttcttc taattccgtt ttcccttttg
    14281 agggagaagc aattttcttt gcctgtgata ccagcttgtc tttttggttt ttgaattgtt
    14341 tatcacttat atgtgattta acaactaact tctttcttct cggtatcatt ttaatcttga
    14401 aaccaagaaa gtcggagtat ctttttctaa catttacaat tcttgttttt tcttgtgata
    14461 cttccaattt taatcgttgt tcaatccatt gagtgattgc tattttggct ttttcagcac
    14521 tttccttgta gcggcagaaa actctaaaat catctgcata acgaaccata tacatttcct
    14581 ttaactttgt tttcttcatt tctttgtaag cgttgctttt acatgggcta ccgcttttat
    14641 tgatatgaac cacatagttt tttgtaacag gattttcctg ccattggctt tctacccaat
    14701 ggtctaactc attaagaaca atgtttgcta gtagtgggga tattattccc ccttgcggag
    14761 ttcctttctc tggatatgtt attgtaccgt tagtcatttt gattggagct tttaatatcc
    14821 tttttaaaat gaatatcaag tgcttgtccc gtattcccat agcccatatc tgttttatca
    14881 gcttggaatg gttcacgttg tcaaagaaac ccttaatatc aaattcaatc acataatgta
    14941 gctggctgat ttgtaggcgg ttataggttg cttttattgc attttcaact gacctattag
    15001 gtctaaaacc atagctgttt tcactaaatt tagcttcgca gattggttct aatacttgtt
    15061 ttatacattg ttgtataagc ctgtcccaca tacaaggaat acctagaggt ctggttttac
    15121 catttggttt tggtatttct tttcgcctca ctggcttagg tcgataccca tgtggactgc
    15181 ctgcaacaat gtatcttact tttttgacaa ctgtttctgc tggcaatttg ccaatatctt
    15241 taattattgt accgtctgtt cctgctgttt tactgcctgc atttgctttg atatttcgat
    15301 atgccagtaa tatattttct ctcgatagga taatatccat aagatgagtg aaaatatctc
    15361 cattcttact tttggcatat aaatcatcaa aggtgttttg catttcgtaa tattcagcgt
    15421 gtcttaaatc ttctacacac aatgtttcat ttttattttt aggcataagg cttcactcct
    15481 ttacttgaaa ttgagtgagc ttttttatct tactcgtaat ccttattgaa acaacataat
    15541 acttttctaa tatatacacg acttgagggc attcctccat tctcattaca agaatttctt
    15601 aggttcgccc tctgcttttc agcattagtt caactgctta ttgttcttcg tcagtttatt
    15661 ctcttgatga gaacccaata cctttcctcg ttccgataat cttatctata catatatatc
    15721 cttaggtcac tagctataag cctgctggct tgataccgcc tgtaacgtta tatggcattt
    15781 cataacctat attcttactt tgccacacca gctacgattt ctcgtacctt tgcatttcta
    15841 caaagttcaa atttagaccc gtacattcgc tgtttcgtca gttccttata gaacattcta
    15901 accatagata ttttatagac ccccgacctg ttggatacgc tacccacctc tggatagttt
    15961 tcgatagaag atatatgttc atcaactatt acggtatctt tcagccgtct ttaccgagct
    16021 tcaaacattc tgagtttcct catacaatgc ttgtcggagg ctcagggcag gcgtttcaga
    16081 gcgttacttc atcattccac ctgtcagatt atcagttctc ctaataacca aactttttcg
    16141 ttcttttatt agtgccttag cttttcacta aggaacgagt cgcacataaa ttttgtccga
    16201 aattcatctt gtcactttcc tttcttttcc attgctcgat ccgctgctgc acttgcattc
    16261 atcaagcaca tcacagtaac accaagcata ctgccaccaa ataccaaaaa aatatctttt
    16321 acaattccca tgacgattcc tcttttcata taatcaaatt ttcaattgcc atactttgtt
    16381 gctccaaaat ctttttatgt cggtctgata agcgtgcatt ctgtaccata tcctggatat
    16441 aggttgtccg attcaatcga tccaactcct tagccatttt ccacgtaggg gcgacttgtc
    16501 ggcctagcca attcaaggtt cgttcaatgg tatacggttt tggctcggaa gttaattgaa
    16561 tctctttccg attccgtcca ataaaacgcc cccattgttc attcaagggc cagttggttc
    16621 gccttttacc ttctacttta tccgcaaatc gcaagtaacg attgataatg gaaaacgtgg
    16681 tgctctcaat gctacgacct tttaacaaat cttgaatcgc atgaaaagca cggtcatttt
    16741 tcagtcgaat ctcaaaacga tttttcgtct cagtttggtc taatggaatc cctaacttga
    16801 tatattgttc atagtctttt tcatacaaac agaaataaac ctcactcttg agactgccga
    16861 tatataaggt attgcccatg ccgtcctttt catcagcctt taaaagttcc ccggaacgat
    16921 aacttttaaa ggtacgaaac aaggagatac attcttcctt ctgacatttt ttcgttagct
    16981 caggtatatc caatagcccc actcgatcat tgattgccaa gtccaagcgt ttcatcacgc
    17041 caccggcctt tagacaatcc tcgaaaaagt cgtaccagct acgcttttga gcgagtaaaa
    17101 aagtttcaaa ttgtcggcaa cctcgcccct ttaattctaa aagcacacct ttatcttctt
    17161 catgagacaa catcaccaca atatcaccca tgacatactg ttcttgatag gagtaaaagg
    17221 cataatcttc atggagcata tactcaaatt tcaaatggag aatttcttga ataatttttc
    17281 gtgcatccgt tgtgggaaag cgaatcctta catagtcaaa cagtaacgtc aaaggcaaat
    17341 cgggattaaa gctttccagt tggtcaaaaa ttttcctcat ggtttttata gatgcggtta
    17401 cgccaccatt ttctatctga tttaagtacg gccgactaag tccacaagcc gtagccaatt
    17461 tattttgtga aacgccgtat tcgttgcgtc ggtcttttaa tagccgataa tctaaattcc
    17521 gttgtgccaa gttctcacct ccaaattcaa ggtgttaact ttttcaaatg agttaacacc
    17581 tatacaaatt acttactatc tttgatacaa caagcattct taatggttgc ttacttattt
    17641 tttgtgtttt tgtacccccc tgttagatac gggggtgaga catcatggtc ggctaacgcc
    17701 gtccatgaac aggcacagca ccacggagga tttctgcttc gcgaatcctc cgcggtcagc
    17761 gcctaacagt cagttgtgtt ggtttaggtt actcatctgt aataccattt acttccaact
    17821 ctgctttcat ttctaacaag tattgacgaa tatctggttc ttttgcttgg tccgcaatcc
    17881 gctcaaattc tgcaattact tgatttattt caattcgagc atccgtctcc tcattcatta
    17941 aatatggatc gccagcgact ttgacaccat tcttgcgaat atcaaatttt aaccgtcgca
    18001 attgttcttc taattctggg tctgactgaa tctttccaat cacccaataa atttctccaa
    18061 tcaactcatc ataaaccatg tacatccaac tcttttaatc ttctggcaat atcaaaaatg
    18121 accggaactg ttacagagtt tccggcttgc ttatacaact gactatctga attgacttga
    18181 gaatctcgat caaaagccca atcgggaaag ccctgaagtc gccaacactc tctaggtgtt
    18241 agcttccgaa tttgatactg atccgtgacg atcgcttgtt ggtctcctgt tagtaaggta
    18301 tgaacactct gttttcccag acgacctcgg cgacttgtgg aattaggaaa agccagattc
    18361 acactgtctt ctggcttcac ctcttgatat tctgtttcat tttttcgaat catgattttt
    18421 gtaccacctt gtttcgttga caaggtgggg gcggttccag taacttcata aactcgatta
    18481 ccttgttcaa actttcccgg taatagtcct gctacagaga ttccatccct tgctggcagt
    18541 gcgattttga ttccttcatc acctgttaag gttggcgcta cgccatctga accatagact
    18601 tgtccaccca ttcctcgatt ggaaggattg atatttacca aatttctgat gttttgatca
    18661 gatgttgaag acggtccaat gataggaaat acttgttcgg tacatgcgtc tcgagaatgt
    18721 ccgataagga atatccgctc ccggctttgg ggaatgtagg cctttgagtt aagcacctac
    18781 cactccacgt cataccccaa tccatccagc gttcggagga tcgtctcgaa cgtagcccct
    18841 ccttcgtgat tgagcaatcc tcggacgttc tcaaggaata aaagcttagg tcggagaaga
    18901 gtggtgaacc gagcgatttc aaagaataaa gtacctcgag tatcggaaaa tctttgccgc
    18961 tttcccgcaa ttgaaaaagc ttggcacgga aatccgccgc aaaggatgtc cactggtccg
    19021 agggattgaa taaactcatc tgatacactt gtgatgtcat gcatttccac ctccttactt
    19081 gtatcatgaa ttgctttata actacgtcta gcaaatttat caatttcaca aaaaccgata
    19141 caatgatggc tcgcctgttc catacctaaa cgaaagccac caataccggc gaataaatct
    19201 aaaaatctca tacattacct cattcattgc aaagaaaaaa gccaagaaca ttttgctctt
    19261 ggctcataca ttattaattt gtcctactat tttttattta atccaactaa tttccgttgt
    19321 ttttcattgg cctgatcggc tacatattta atcaccgttt tgaactcttt tgcagtagca
    19381 ttttccgata aatccgcaat gctcttattg tatttcttta caattttcgt tacttgttct
    19441 ttctcagtca tgtaattgaa cctccaaatc tttcctacta taccctagtg gtaaaaataa
    19501 ttctagatta tccgtagcat aatgaacttc ggaaatatta ttcgtataat cttttattat
    19561 gatatgaagc aatacatctg gatgtttact ctttactttt gcaatgttct ctcttgattt
    19621 gaaaaaagcg ttaataaatg cctttttcgg cacatgacgt ccctctgcaa tttcacgttc
    19681 ttgtgtaaat ttccaagcga ttttagggtc ttgataaaca tagaaaatcg tcactcgaaa
    19741 atgttttttc aacgcccgcg agatattttt ttcagcactt aatattgcaa aagttgcatc
    19801 cagaataaaa gaatagccat gatctaagac atatctaaat gcctgctcta ccaaccaaga
    19861 agatgctttt tgaaagagac tagagttttt tccattataa tcaggaaact gggtgcgaaa
    19921 gtaatccgca tcaataatca catggttatc ataattctca gctaatccaa tggcaacctc
    19981 tgattttcca gccccaggac tccctgccat aaaaactgcg tctcgtccaa cttcggggga
    20041 tttccctttg ataatataag aaataaactt atccttattt gcttttgcat actctaaata
    20101 agaatcatta ctttccatat taattatccc ctttcttcct actatataaa agtattatac
    20161 gttacttgaa gtataaagtc agtattgaag atcactcaat cattcatctt ttctaattta
    20221 ctaattgaat ctaagaaatc ataccctttt ggtacaagtg gcgtataaaa ctcactaatc
    20281 acactgccac ctgtatccac ataacctcga cctttgatgt gcttcataaa gaagtttttt
    20341 tcgacctccc caaacatcat ggaatatccg agttcactca tacgacccaa agccacgcga
    20401 aagttgaatt gatcgcggat tccgtctcct aaatatttcg catccggcct ttggcaagcc
    20461 aaaatcagaa agaaaccaga ttgacgaccc aacatcacga tttgtttgag cttattcaaa
    20521 atcaccgcac tttctttcgt cgttaacatc tccatataag ccacgtattc atcaaagatt
    20581 aaaaagttgg gtggaagtcc aagataggca taattctctc ctgttttgta gttagacatt
    20641 tctttcattg ccttgctacg agccatcata cgttcataga aatcttccac acaagcagaa
    20701 atttcttcct tttgtgaata aacatgaggc atcaccgtac ctaaatcagc taaatctgca
    20761 tttttgggat cgaggataaa caattctgca tctgacttca atagtgcttc gataatggtg
    20821 aggaggaaat aggtcttccc tccacccgtg ccaccagcga ttaacatatg gggtaaagaa
    20881 tcataagccc atacttgatt tttcatcaat cgcagagtcc cattttctgc cactacttcg
    20941 tctatcccaa ttcgattggc gatcatatca tacagtaaag tatactccac ataggagtct
    21001 ttgagttcct tttctactaa ctcacaatac agtccgcttt ctaacttctt ttccaatttt
    21061 aaaagctgat cttggtattt cccaagtgaa atttgaacgc gaatagacag taatccatct
    21121 ttcattcgat aatagatttt ggggaagtaa ctgatagtct ctctggttcg gctactattc
    21181 aaatctttga aaaagccttc actttgagtt tgtttcactt cataccaatg gttctctaga
    21241 atcatccgag ctagcttttg tcgatgccac aagcttcgcc aatgatcaag aaaaaagtga
    21301 atataaagca atatcatagc tcctgaaaaa gcgagacttc caagcagaca tactaaatct
    21361 tttatagacc aaacgatttc aatagtagaa agtgatagct tagaaatatc aaattgtcta
    21421 aactcttgaa aataaaagac gctcatccaa ccgatgaaca gagcgagtag ccagccaaga
    21481 acaaagtgat aaaccaagtg ctgatctcct gcgcgtatgc gatgtccttt gtacattttg
    21541 atggtttcca cctccaatcg aaaaagccca ataggatttc attaggcaat ttcaaaaagt
    21601 tatgctagtc atttactgct acgaggaggg gagttgtttc gtttcaacca attgatttaa
    21661 aaagccttca atagcatccg gcatctccac accaatttct tccaaaatgg attctgcctg
    21721 ccgacataag ttttcattta cttcgacaac tataaagaaa gactcttctt ctcctaacca
    21781 gtctagtaca tcagagtctt cttcactgtc gctattttct ccaagtaaac cttgatgtat
    21841 aatcagaaac attttttcat cagaggttaa tgctttaacg agttgttcct cagtcagctc
    21901 gccttttcca tattgatcga gacaatctaa aatatgttca acattaattt ccataatctt
    21961 cacctatttc tttctttcat tttggttcgt aggatttcct tgattcggct gccgcttcaa
    22021 gactaaatca tccgccttaa tgaaccaatt aacggtagtt ccttctcgaa aaacataatt
    22081 ggcaacggta tccacgattg gattgaccaa ctctacctct gcatcataag caaactcgcg
    22141 taagggtaca ttagctggga tactaacttg aatcattcgc ccttgtgcag aggattttaa
    22201 attataggtt cgttctttta cctcattacc aattgttcca tcctcatttt gcttccgtac
    22261 ttctcggcgt aatgcggaaa aacgcaactt cccaaatgtt aaacctgaat ctacgacaat
    22321 accttctgtt aatctcatct tcttttcctc ctatgctttc actaaatcat caacatacaa
    22381 cacgtaatca gtaaacccac gattctcaat ctcatagcct ttggcaacca aatggggatt
    22441 cacggctttt agcggttggt cttgatcaaa atccttttca ccggcttccg cagctactac
    22501 cacctcaata tcatcggccc gttgcttact ggaatacaaa tgataactgc gaccaatcac
    22561 cgtagtattc cgtccatatc cttctgttat aatttctcct tcaccggcat aacttaactt
    22621 tccaaaggtt tcagccatat ctggcacgac aaatttcaat tccatcttct tttcctcttt
    22681 tcattgttag ttttggatac aaaaatagcg cgactacttt tttaggaggc ggtcgcgcac
    22741 gttggttctt aggatttact tgtatcatct catcacctta gttccggcga ttccagaaat
    22801 aatagcccgc cgtcgcaaaa atcaaagtaa aaccaatgaa cagtaaaaca ttggaatttt
    22861 tctccccggt ttgagggaag gtcttcactg tgggactaga ttcttgagag ccacttggaa
    22921 cagttggtgt ttccggttgt ttcggcgtac ttagtatggt tggaacttct tttggtgtta
    22981 aggtttgaga tttttctttc aaatcttcat tgtgttttcc attgatattc ccatctttat
    23041 cgtaattgat ttccgcaaaa gtaaacttgg ttccttctgg atattttccg gtatctactt
    23101 ttttcgcaag cacagttttg gtgaattctt tatcatttac ttcataatca atcttgccag
    23161 atttccaaat ttctttgttt gtaccatccg gtaataaagc atacagaatt gtttcgaaag
    23221 cttcttttga gccatccagt acatcatgag taatcgacac atcatcaaac atatccacca
    23281 catcaccatg agtaaaggtc tgagaaccgt tttctaggtg ggcctttgtt tggatagaaa
    23341 catggtgttc cactgtacaa ctgacagttt gggcttggtt attcaagcta acatccttcg
    23401 ctactggctt atcgcctgct tcaaaagctt ccttattttc atacacatag ttgaataaga
    23461 caatagtttt atttaaaact tgttcggcgg ttaatttatg ctgaattttc caagttcctg
    23521 ttttctcttt gttcgccaac gttgcgcttg tttctgcaat caccactggt ttggcttttt
    23581 catctttttc ttgggcagct tttgtcgcat ccacatcaat ggcttgcgct accacatacc
    23641 agtcttcttt gatttcatgt agattgtaac tcaatttatc aactagctcg gtagaatcca
    23701 gagaagttaa ttctttgttt ccgtctttcc aagtcgcaag agaagttaaa ctatcttctt
    23761 cctcaggcaa atcatagagc attaaacggt tcaaactaac agaaaatgct ttgttcgtca
    23821 gcttctcgta aggaacggtc accgttttaa ttggttgttt ttggtcttgt tcggtaatgg
    23881 taaagacata ctcactcttc acaaagtctt ctttgttttc cttaaaagta gaacggattt
    23941 ctaatggcgt aatcttttga aaaccttctg gggcttctac ttcttcaagt aaataatccc
    24001 cataaggaag attttcaaac ttgccataac catcaaaccc taattgctcg ttataagctg
    24061 tggtcgcttc atcttcggca cctgtgattt cattggtccc ttccaatggc gacactttaa
    24121 aggtcagatc attgaagcca gtttcggtag tgcccgcagc tgatccagca aatttaaaga
    24181 aatcaaagcc aaagcgaatc acttgttctt ttgccgtaac atttcgggta atcacggcat
    24241 ttttttcgct atcatccacc tttttgatgg atacaggata ctttgtttca tcaaggctat
    24301 atccttcggg cgcttttgtt tcttgccaat aatactcgtt gatagctaaa tgtttaacgg
    24361 caacttggtt cttttcgtct aaagtcaaag tgaccgtttc atcagaacct ttcgttccct
    24421 tcgctaactc tggtttaaaa gcctcactcc atttaacagc ttttccatcc ttagcagtaa
    24481 acaaggtgta ttcagcaccc tcaaagactg ccttaccttg tgctttatcc ccagtatctt
    24541 tgtcttcttt cgtcaaagtg gtttcgccag tgacttcttg attttgccct tttacgttac
    24601 tggtaacaag ggctacggtt tgattggcat acttcaattc gacttttaca ggtttgaacg
    24661 tattcacgaa cccatgacta gctttagttt cggtcacata ataggttccc aattccaacg
    24721 cattagcaat ctcttttggt gtttccgcat gaccgttttc atccgtggtc atttcttgaa
    24781 cgatttcacc ggttggactg tctttgcgaa tggcaaacgt attaccagct aaggaataat
    24841 tgtcattcca aagatcactc cctgtttcaa ctccgctttt atccagaatg atttgccctt
    24901 tttcccgtgc gttttttgaa gtcacgtaaa tggtttcgcc tgctttaatg gtggtagtca
    24961 tgggggtggt atcaatcgta taaggcgccg gtactgattt ttcggtaatg gttacttttg
    25021 taccatgagg aatctcatcc aatgtagcaa tgccttcttt gtcagtagtc acgtcttttg
    25081 caggtaaagt ttttccaaag tctaaatgga aaaccgttcc tggtacaaca tcacccgatt
    25141 ctttatcgac ttttttgatc tttaaagaac cctccgtttc cacatcaatt ttgattgtgt
    25201 aggtattagg tttatcaatc gccccggcca ttaaagtctg ttggccagcc tttttatagg
    25261 cgacaggtgt tccggtacca gcagatttct taagcgtcag cacaccactt tcttttgaat
    25321 tggcatttgg ggtgattatc aactgattac cattcacacg ataatcaatg tttgcggcat
    25381 tttccacaac ctcatcgaac tctgacaaat tcagattatt cgtatccgtc acagtagtcg
    25441 attgccctaa tactgtttta gccgtactat tatggaaggt tggtttcttc tgataatcgt
    25501 caatggcttg atttattttt gcctcaatgg ctgcgatatt tacggcacta ccatctgatc
    25561 gttttattga gtgaagggta tacccattaa cttcttgcca gatcatcttc tgtgccacaa
    25621 tatgagtatc tgcatctgta cctacttttt tccataaaac ggaaactaat ttggctttat
    25681 cggacatatc tggtaacggg tttttctcat agccaggagt gaactcattg taaatcggga
    25741 ctcctggttc aatacagaaa atatcttgtt taaagccgtt gtacactgca taatgcggaa
    25801 cagtgacttc tgacattgga cgaccatcac taaaagttcc ttcaacagca tattgatgtg
    25861 ctaaatctag ttctacggtt accgtttgtg gatgggtaat ttcatcagca aaagtaatcg
    25921 taggagcaat tgctccaaca attgcttgaa cagccaaact caaaatagtt aatacacata
    25981 atttcttttt ttgtttttta tacatgaaat gttctccttt caaattaagc acaaaaaaat
    26041 aagatgctcg cttgaacatc tttgtttata aagtcttttt aaaattttta ttgactgaat
    26101 agaatggatt tgagaatgaa tgagcctaaa aatttaatct aaaatacgaa atatactgcc
    26161 tttaaattag aacacatttt agaacacaaa catttcaaat ttaatcaaat ataataaaat
    26221 atatttacgg gaaaaccttt ataaatcaag gtttttcaaa cttattcaat gatacgaaga
    26281 aaccaggtct taagaaagca cgtaaagctt cacagttttc aaaacgttaa tcgttgttat
    26341 accaacgatt tcagacactt tctcattgcg agaaggtgtc tttttttcgt tctggtaatg
    26401 agaaaggtaa tgacaatatt ataaaccagt gtaagcaatg aatttttcta acgcatttcg
    26461 ttgagctttt tcagtaacat gagaataagt gttaagggta gtttcagcat ttttatgacc
    26521 caatcgatct tgtgtttctt tgatacttgc tccaccttct agtagaagag tagcgtgagt
    26581 gtgccggaat ccatgaatag taacgtgctt aaatttatat ttcttctcta aacgtttcaa
    26641 tatattattt gaatagtccg catgcaaagg ttgattaatg tcaccgtctg catttacata
    26701 ggtaaagata agttgatttt ttgtatttgt atttatgcca aactgcaaaa gctctcgagc
    26761 ttgttctttt ttccagattt ttaacatttc aatagtttgt gcatcaattg gtaatattcg
    26821 ttcggaagat atattttttg tatttttttg aatcctgaca gtttttcttc ttgcattctt
    26881 ctcttcattt cgaatagttg catagctctt tctaacatac attagctgtt cttcaaaata
    26941 aatgtcagac caatgaagag cagctagctc tcctttacgt ataccagtag taatcaaaag
    27001 ctggaagatt aaaatatgtt ttaaaggctc ttctttattg agaatatccc aaaaagcttt
    27061 tagttcttct aatgaaaagt aattttcatt ttctttcttt tcccgctttg gtagatttgt
    27121 atttgccata ggatttcggt gtaatagctc tgcaaaaatg gcatactcaa atatttgaga
    27181 gctgtaagac ttaagctgtt tgatattctt gaattttaaa gcccattcat tgactgcatt
    27241 ctgacagtga acaggagtaa tcttagaaat ggacttattc ccgaattttg gtagtatatg
    27301 caagcggaaa aggtcttttg tacgttgata tgtcgtttct tgtacacgat tcctataaga
    27361 aggcaaccat tcttcataca ctgttataaa caagtcatta gaaggcttat gatagccggt
    27421 atcttcaatc tcgacctttt ttcttgcttc gtgtaacttg gcttcttttt cagttttaaa
    27481 cccttttttt acatagtatt cttgctttcc attttcatct ttacgaacat acaagcggac
    27541 actatatcgt gcaccgcttt ttgttgtgta cttttgtatt gacataacta atctctccaa
    27601 tctgataact tggcgagttg gctgattgaa gaaatagaaa atgagaggag aaaaataatg
    27661 gatgcaggaa ttacagtaat gttagataaa caacaaacga atcaattgaa aaattatgtt
    27721 tttgaaatga caaaagaggc tattgatcaa gcaagaattg ataccggatt agaaagacca
    27781 tttctaaaag gaaaagagat ggctaaatat ttgaatgtat catatacaac ttttttgaaa
    27841 tttaaaagaa tgggattgcc agttatttta ttagaaaaaa tggagttgtt ttcaaaagaa
    27901 gaatgcaaaa aatggatatt gagtcatcaa atttaaaaaa cacctcgttt tttaaatttg
    27961 atgaagtaga aaaaattaaa aagagtgttc ccgtcagttt gcagatcggg ggaacactca
    28021 ataataaagt tctgagaaaa ctttatttga atctattata gcaaataaaa tcagaagcag
    28081 gtgtgacaat gaatgaaaaa gaagttgaaa gcttagttga aaagcaaggc tattctaatt
    28141 ctgatatata tgcagaatta tactatcaat atcctatttt tttaaacgta aatgaaaaat
    28201 ataagaaaat gaaactaagt tctaagttag tttatatgtt actaaaagat agaaatagac
    28261 tttcattgaa aaataacttg tatgatgaga atcaaaaaat ttttttgata tttgaaatca
    28321 aaaatctcgt agaaatttcg ggaatgtcaa aaaatacaat cttatcagca ctagatgaac
    28381 ttcaaaaagt taaacttctt gtgaaaagaa aaaatggctt caataaaagt aaaatgcaaa
    28441 tgttcccaaa tttttattat ttgttaaagc ctgttctgtg caaagatgat gtttataaaa
    28501 ttaataagat aacccatcaa gaaaatagac aaaaaaactt gatagttcaa aatttgaact
    28561 atggaacaaa tcaatattct gttgatagtt caaaatttga actatgcgac acatcaatga
    28621 aaacaagaga caaaaacaat tttgctgata gttcaaaaaa tgaactagaa ttatataagt
    28681 cttataaaga tagtaaagat attaaagaat cacataatga tgatcttctt gaatcacttt
    28741 caactaaaaa taataaatta gatgaagaat tgatcgaaac atttattgaa gaaaatcttc
    28801 ttaaacaaat atggggagaa agtattgtga attgcttaaa actggctagc aatagtgatt
    28861 atcgtcaatt cgacaactgg tacaaaaaat tcaaatatgc gattagatct gctgaaaaag
    28921 aacaaaaaat tcaactgaaa attatctatg aaatttgtaa taacaagtat tttgtagatc
    28981 atgttagaga acagctatca atgactttac gtgacttgat acgaagagca aaaacagatc
    29041 atcgtatcaa acaaaaagac gattatatct ttgcttctct aaaaaataaa gcgttagaac
    29101 taattgaatt gcaaatcagc gaaggaatag ataagcaata agaatagaat tgagtcaaat
    29161 gaaatggagg ggtatctcca cttcatttga gaactttgaa tataggaggg gttattttga
    29221 ttaaaaatcg tttaatagat caagtttggt gtctagatca aaatacagat agtctcgaat
    29281 taatcgagac tatttgcttc aacactatag ttctcgattt aagagctgaa aatgataatt
    29341 gtgtaactca tgtcataatt aatcaaaaaa tggctcagaa gctctctgag agcctcagaa
    29401 aatgggctaa gggaggtaac gatgaaaata attgaaaaaa agattgccaa taaaaaaata
    29461 aattggttgg ttgttaattt tcttgttctg atagctatga ttatttttac aagtaatatt
    29521 gctcatgcga gtattttcaa ttggtttgat gacacaaaaa gtcaaacaga gtttttgaat
    29581 aattctcttt atagacctta cctaaaaaag tacaatggag atttccttag tcagttcggg
    29641 atttggctcg gatgggctgt ggtaaaaggc atgtttactg tgacagattc gattcaaaat
    29701 atgattccag atgtgctgga tttgttcaat ttcattgaaa gtacagggct aaataatgtt
    29761 tatcaatcag ccgtaaatac aattgtcatt ggattaatga tcctttcatt gatgtttgtt
    29821 ggttacaaaa tgattactgg aaaaggaaca gtggatttaa aatcggttgg aatgaacgta
    29881 gtgatgtcta tagcattaat acttttaatg ccaaccatga tttctagtgg tattcaattt
    29941 gctaaaacat tttataagga ctctactacg attacaaatt cagatgacgg agtcgcttgg
    30001 tcattgataa aacaaggagt aacagattta gcatatatta ataaaacaga tcagtactca
    30061 agcattgata aaacggagga tcgaaataat ttaacacgaa aaaattttca acagacggat
    30121 ctcacacaag tgttaacgga taaagtgatt gataaattgg aaaaagaaaa tccaattgcg
    30181 gacaatcttc gttatgaatt agttgaaaat tctaataatg aatttgttgc tacaaagttt
    30241 tctgacaact tcttatcaac attttctgat agcttgaaat caggctatta ccgataccaa
    30301 gcaaatctat gggggatttc aattgggttg acagcgttag caatcgccta tgtgttcagc
    30361 gcgtttgtga tcattacagc aatactagaa cttgcattta aacgtgtgtt aggtgttctt
    30421 gtttttgcaa cagatattga gacaggacag cgttcaaaag ttgttctatc agatattcta
    30481 caatgttact taactgttgg gtttcaagga tttgggttat caatgtttgc tatgtttatc
    30541 aattttctga actcaggaca aggtatctca acaaatattt ttataaaaac aattgcttat
    30601 atctgtgccg tttttgtttt aatcaaaggc agtggaacag tcatgagata ctttggtgtt
    30661 gatattggac tcaaagaagg ctatgggcaa cttgcttctg cttttggaat gggcgcaatg
    30721 ctgtttagaa aaggatcaaa tggatttaat cgtgctaaag gaagcggaga aggagaagat
    30781 cgaaaaccag aaaagaattt cggcgaaact ctatcaaaaa aagctggcaa aactggaaga
    30841 gctttgggat atgcccatga acgtggatta tccggtttag cttcagatgg agctacaatg
    30901 gctagtgaaa gagcaacaaa accatttaag agtatgcgtg atatagctaa tgataccaag
    30961 aataagttta aagaaggttt agatgatggt acagtgtccg ctattaataa aaatagcaaa
    31021 cctatgttag ctaaaaataa agaagatgaa actggaaaat atgctgattc cgtgccaaca
    31081 cgtctttcag atagaaaaga tggtgctaaa gttgaaaatg ccgatagaat tatgtctagt
    31141 tctgaacgta tgcgtgaagc aatgaaaaat aatgctgaat cgaataataa tcctgcaagc
    31201 gcaattcagc aaaaagtcca acaagatatt gaagaacgta aaaatgctat gcacggtcaa
    31261 gctaagtctg ctgaagaatt aattaatcag aagcgtcatg aagcgaaata cacgcctgaa
    31321 gcaatgaatc gcgaggaaat aatgttaagg aaacgtgtag aagggcggac aggcgctaat
    31381 attgacggaa aagaagcgtt gaccaaagaa agaattcaag aagctaaaaa ttcaaataca
    31441 ggattagaaa aattagtcaa agaaaatcca caaaattcta caagtagtca tggtggccga
    31501 tcagtagatg tccgagaaaa tattcaaggt tcactgaatg gtcatgttgg acggaatgtt
    31561 gatgtaagag agaatttaca aagttcttca aatgctcaag gtactaagac aattgatgtt
    31621 cgagaaaatc tgcaaagtag cagtacaagt caaccaaaaa cagtagatgt tcgagaaaat
    31681 gtacaaaatt ctacaagtag tcaaggattc aaaacagtag atgttcggga gaacattcaa
    31741 aaagatagtg gagaaatgaa agaaaaaaca caaaaaatca atatcgttga agacagaaag
    31801 tcagcgaaaa aatttgattc aaatcatgaa acagtgatta ttgatagtga aatccgtgaa
    31861 aatgataagg gatcaaaatc aagacgaaga ttcacttatg aagacaatga gttattcaga
    31921 gatacactta atgatcctaa tccacttttc gataatttat taagaaataa aaggggggga
    31981 ttgtcatgca attaattcta aagattagta cgcatgattt cttagaactt gacgaattat
    32041 gtgaatcagt aaagaacgca acaaatgaaa aaatcacggt cactaattat attgaactga
    32101 tgattcaaga agaattaaag atgaaaaatg aaatagagag caatttcaaa tgttgctctc
    32161 tagaaaaaaa tgtgagggga taatcaatgg atgataaaca aaaaatgtac gaaaaaaatc
    32221 gcaaacatag tgaggcctta aattttcgtg tcgataaaaa gacttatctt gaactgacat
    32281 tgattgcaaa acaaagggga atttctagag cagacgtttg ccgtgagcgg ttaaagggac
    32341 tcaaatatga accgccgttg ttagctgaag atgatagggt agttttaacc aaacagttaa
    32401 atcaaattgg taacaatttg aatcaagcgg taaaggcatt aaatatcatt gctaaatatt
    32461 ttagagaaga atctgaagat aaaaaagaaa agagcctaca ttttagtttt gatgctagcc
    32521 gttacaacat ttttaaagat gaacttgcga atagcatagc aaaaaagttg atgattagtt
    32581 atccagatga catttttttg gagtccaatc ggagtgcccc ctcttttttt aaattatcag
    32641 aagtagaaaa agaatatttc gaatattgga tagaaaagca aactagaccg ggtacgaaag
    32701 aagagtattc ccaaaaagtt gatcggaatt taattcactc aattcagatt attgcaagtt
    32761 taaaagatga ggtgaaacaa ctttgggagc tactataaca tcgaaaggac gcaagaaaaa
    32821 tttatcctcg ctattacaat atgcagctaa tccttcaaaa aaagaaaaat gtgttgcagt
    32881 ctcaggaata aattgtagtg atgatagtga ggaagcactg caagaaatga atttagtacg
    32941 taccaagatg aataaatcta aagatatagc acaagcgttt catgttattc attcgtttga
    33001 taagagtact tctaaagagt taagtattga taaaatgcac gaaatagctg tcgaatttgc
    33061 agagaaagct tttccaaatt cgcaaatcat tgttgcaagt cacaatgata aagatcattt
    33121 tcatagtcat cttgtcatta ataatattaa catggaaaca tgtaaaaggt tgcgtattga
    33181 ccctaaagat ttagaactaa tgcgaaaaat taacgatcaa gtcctcaatg aacatggtct
    33241 tgaatcagtg aataatgagt actatgaaaa cttagaaaag agaaccaatc tttattcaaa
    33301 cgatccttct aagatgaaat atggaaaaat taattatcaa gagtttgtgc aaaatgcgat
    33361 cgaagcaacg ttggaaaaat gcgaagtgaa ttcttttgaa gatttttcgg atcatttggc
    33421 aaaagaatat aacattgaag tttatcaatt ttcaaaaaca aataacaaac ttggctatgt
    33481 tctttacaaa caaggtgtaa atttctatga gcgtagaggt gagttaatta ctttaggaag
    33541 agataaacaa tctagaaaag aaaaaagtca gtatgtcgaa cgtactttta gtgcaagaaa
    33601 gttagggaaa agatattcat ttgaatctgt ttctgaacaa cttgaaaaga atttagaaga
    33661 atcacatata aaaaattttt ttaatatgga aagagagcaa gttatgtcgc taattagtgg
    33721 agtaaattac aaaactggtg agttaaatgt accgtttgtg gaattagatt ccatcgcaca
    33781 aaagcaattt agcgaccgtg aaggcgatga aaaattcatt aaatatgatg acttcttgcg
    33841 agaggtagac aagcattttg taaatacaat gtctttagaa gatgatcaag aatacacgat
    33901 taaacttcat acggatgtga atcctcaaac tttacgtagt gcgaaaagta aaacaatttc
    33961 tattaaaaag actgatcaga aagagttatt tctaccggca aagggttttg aaaattgttc
    34021 tcatacacct tctgctaaac agattcacta tcaaatcagt cgcataatga atgacgatgt
    34081 aaaaatgtat cgtgctaaaa aggattatga attcacacaa caaatgattg aaaatcagca
    34141 aaaaaggcaa caaaattttg aaatggaatt ctgaatgggc ttgttagtgg actttccagt
    34201 tttttgccta tgaagagttg cttggaaaga agcagttttt aggacatacg ccagctaccc
    34261 atctacttgc cagtcaatcc gccccgctca cgctaggcta ctttctggca agtcagatgg
    34321 cgggtaaatc tctgagggag caagctccct acagactccc tcccaaaaaa agaaaggtgg
    34381 aagaaaaaaa tgaactatcc atattttaaa gtctcggctt cagaagaaac taaagaaata
    34441 ttcaacaatt tttacaacca aaacaaagga atttttggtt caaaggcaaa tatgtttcgt
    34501 gttatggttt caaatttacc agtgttagct agtccatcaa ataataaatt taatgatcct
    34561 gaaagcatta aatttgaaca aaaaatttca gaactagaat caatgataag taatgaagta
    34621 attgaaaagc tggatgacat tgatcaaaag ttatcgtatt ctctaaaaaa caaatacaaa
    34681 acggaggaga aaaaagatgt ttaaagttta cttcccgttt cagtggctcg ttaaaggaat
    34741 tcttttagtg ctactaggat tgattctttt tggaagttat ctaacaatta aagccagaca
    34801 ttttccagaa gaaaagccaa taaaaattgt aacaaaagat ttaaaaatag gtgaaactta
    34861 tcaggcagat ggggttgaac taacatttaa aaatattgaa gtgaccgaaa aaagaaatga
    34921 atttgcacaa catgatcgtg tattacaagt gacctataca cttataaatg atacagaaaa
    34981 tccgatacgt ccacaacaat ggtcgattga aaataaggat ggtgaagaac tttatgagta
    35041 tgatatgata ttggataatc cagagtatat tgaaagtggc aaagaagaaa cagtaaatta
    35101 ctattatgaa ttaccgattg aaaggcagga ctaccaaatc gtagtacgta gagagaatgg
    35161 ttacatagtt gggttgccat ttactttata agttttattt tgttagtagt ttttaaggta
    35221 atatcagttt tgtgattttt gaaaatggaa ctgggagaat ggctgaggaa aataaagttg
    35281 ttccgtttga aacattagtg ataaataagg aagagtttga gcaacttttt cttgattttt
    35341 ttattcaata tgacatgatt tatgatttta gttcgtcact agatttattt gaattagaag
    35401 cagaaataat agaaaacagt cgagagaaga atggtaaaat cattatttca gtagaaaaat
    35461 tcaatgaatt attctcacaa acatttgaaa tagatccaga ctattatcaa ccacaagaag
    35521 tttttcgaga gtttagaaat aagattattg gttttagtca aactacaaaa tgaaagctta
    35581 ataaagcaag tgttgataga attattcctc aacgcttgct ttattttatg ggcacttcat
    35641 aatagaggta tagagaagag aggtattcat tttggatact attactccaa caaacttcaa
    35701 agaaaatata ggtaaagtgt tgcaagaagt agttcattca aattctgaaa tagaaattac
    35761 tagggattct aaaaatggat tgaacgatgg cgtcattatg atttctaaga gaaaatggga
    35821 gttgttacaa gaagaacttt atttacaacg aacgggtaca tgggcttatg tatctgattt
    35881 a
//
LOCUS       DAFBSV010000018        35719 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.018, whole genome shotgun sequence.
ACCESSION   DAFBSV010000018 DAFBSV010000000
VERSION     DAFBSV010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.018"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(<1..705)
                     /locus_tag="LLB18_000880"
     CDS             complement(<1..705)
                     /locus_tag="LLB18_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBK5243896.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFI"
     gene            1393..1551
                     /locus_tag="LLB18_000881"
     CDS             1393..1551
                     /locus_tag="LLB18_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5243897.1"
                     /translation="MNKKQTCEFLGIDNNTLDKWIRIYNFPVIRIDGIVRFDIEDIKD
                     FMNTFKTI"
     gene            1623..2849
                     /locus_tag="LLB18_000882"
     CDS             1623..2849
                     /locus_tag="LLB18_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBK5243898.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGITSEKYQKVFPTRQLAIKA
                     ENAMKRKIETVLREENANSLELKGKIKFKEFYESKWLPRYELGQTTRSKRAPSYVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQCITAPKKIALEERRIREGNQALSSEELIAWIEAVNTDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFEKQTVRLKHALDKYQKKKFTKGRKDTV
                     IQVPEIVMALLSKWKSVQAEQLLRLKINQTPDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPELAHLSPHKLRHTYATIARQGGANMNQISSALTHSDISTTRIYVNTPDVV
                     DKTVFEAFQRGLNKCD"
     gene            complement(2938..3330)
                     /gene="rpsI"
                     /locus_tag="LLB18_000883"
     CDS             complement(2938..3330)
                     /gene="rpsI"
                     /locus_tag="LLB18_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBK5243899.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(3346..3789)
                     /gene="rplM"
                     /locus_tag="LLB18_000884"
     CDS             complement(3346..3789)
                     /gene="rplM"
                     /locus_tag="LLB18_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBK5243900.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(4308..4775)
                     /locus_tag="LLB18_000885"
     CDS             complement(4308..4775)
                     /locus_tag="LLB18_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HBK5243901.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(4895..6433)
                     /locus_tag="LLB18_000886"
     CDS             complement(4895..6433)
                     /locus_tag="LLB18_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HBK5243902.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            6513..7199
                     /locus_tag="LLB18_000887"
     CDS             6513..7199
                     /locus_tag="LLB18_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBK5243903.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(7400..7927)
                     /gene="msrA"
                     /locus_tag="LLB18_000888"
     CDS             complement(7400..7927)
                     /gene="msrA"
                     /locus_tag="LLB18_000888"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBK5243904.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(8011..8688)
                     /gene="pgmB"
                     /locus_tag="LLB18_000889"
     CDS             complement(8011..8688)
                     /gene="pgmB"
                     /locus_tag="LLB18_000889"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBK5243905.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(8685..9815)
                     /locus_tag="LLB18_000890"
     CDS             complement(8685..9815)
                     /locus_tag="LLB18_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBK5243906.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(9815..11998)
                     /locus_tag="LLB18_000891"
     CDS             complement(9815..11998)
                     /locus_tag="LLB18_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBK5243907.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(11995..13020)
                     /locus_tag="LLB18_000892"
     CDS             complement(11995..13020)
                     /locus_tag="LLB18_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBK5243908.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(13065..13892)
                     /locus_tag="LLB18_000893"
     CDS             complement(13065..13892)
                     /locus_tag="LLB18_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBK5243909.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(13889..14956)
                     /locus_tag="LLB18_000894"
     CDS             complement(13889..14956)
                     /locus_tag="LLB18_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HBK5243910.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(14982..15818)
                     /locus_tag="LLB18_000895"
     CDS             complement(14982..15818)
                     /locus_tag="LLB18_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBK5243911.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(15815..16684)
                     /locus_tag="LLB18_000896"
     CDS             complement(15815..16684)
                     /locus_tag="LLB18_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK5243912.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(16754..18037)
                     /locus_tag="LLB18_000897"
     CDS             complement(16754..18037)
                     /locus_tag="LLB18_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBK5243913.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(18051..19736)
                     /locus_tag="LLB18_000898"
     CDS             complement(18051..19736)
                     /locus_tag="LLB18_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HBK5243914.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            20011..21036
                     /locus_tag="LLB18_000899"
     CDS             20011..21036
                     /locus_tag="LLB18_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5243915.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRLLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(21631..25305)
                     /gene="rpoC"
                     /locus_tag="LLB18_000900"
     CDS             complement(21631..25305)
                     /gene="rpoC"
                     /locus_tag="LLB18_000900"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBK5243916.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(25363..28980)
                     /gene="rpoB"
                     /locus_tag="LLB18_000901"
     CDS             complement(25363..28980)
                     /gene="rpoB"
                     /locus_tag="LLB18_000901"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBK5243917.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            29708..30676
                     /locus_tag="LLB18_000902"
     CDS             29708..30676
                     /locus_tag="LLB18_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK5243918.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            30694..31599
                     /locus_tag="LLB18_000903"
     CDS             30694..31599
                     /locus_tag="LLB18_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5243919.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            31596..32402
                     /locus_tag="LLB18_000904"
     CDS             31596..32402
                     /locus_tag="LLB18_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK5243920.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            32538..33527
                     /locus_tag="LLB18_000905"
     CDS             32538..33527
                     /locus_tag="LLB18_000905"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBK5243921.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(33844..34368)
                     /locus_tag="LLB18_000906"
     CDS             complement(33844..34368)
                     /locus_tag="LLB18_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HBK5243922.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            34655..>35719
                     /gene="scm"
                     /locus_tag="LLB18_000907"
     CDS             34655..>35719
                     /gene="scm"
                     /locus_tag="LLB18_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBK5243923.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT        10272 a         7540 c         6611 g        11296 t
ORIGIN      
        1 aataaatata gtatctccat aggctttttt taaattctct tcattaaata cagattctac
       61 acttccgtga gcaattagat ttcgattcaa aagaataata ttatcaaaat acttctttac
      121 cttgcttaaa tcatgatgca caattagcac tgtttttccc tgatgtttca attcttttaa
      181 cgtatccata attattcgtt cactaactaa gtctatccct acaaatggtt catctaaaaa
      241 tatgaaatcc gcattttgag caagacatct tgctaaaagt acacgttgaa attgtcctcc
      301 agataattct cctatttgat gattagaata ttttcccata tcgacctttt ccaaagcctt
      361 tgaaactctt tgccattctg catttttaat tctttgaaaa actttcattc cggcatatgt
      421 tcccatagat acacattctt ttacttttat tggaaaagta aaatcaatat cagctttttg
      481 ctctacatat gcaatcttca ccagtttttt attgatatct tcattattaa tggagacctc
      541 tccctgatga gggataatat ttaacattgc tttaagcaat gtagattttc cagcaccatt
      601 tggaccaata atacctgtta aagcaccttc ttgtattttt aaagaaatct cgttcaatgc
      661 taaaaaatcg ttataacaaa cattaagctt tttcacttct aacataactt tctccttcta
      721 aatgataatg attatcacga tcatatggta tacaaaaatt atattttagt caaccctaaa
      781 ttttataatt tagatttttt tctgttgctg aagattagaa tgacaaaact atttgaaact
      841 acgcgtatag taagtagctt tcaaaatata taaaaaagga gcgttctcaa atgagaacat
      901 gctcctaaaa ctactttatt ggcgtatgga aaaattatac ttaaagtgga tagcgggttg
      961 aataagttga taagcatcaa aacatttata aaaattattc aagactatgt ctgttccata
     1021 tacaaatatg aaaatcagta aactccattt aacttttttc gtagtgtgtc tttttataca
     1081 tgtttatcgt tattaatagt gaataggaaa aaacctattt ttgatcattg acaattaaat
     1141 acaatttttg aataacgatc cctgctattc gagctagaaa ctcaagtacg ccatgacctg
     1201 attagcgaca aatacttaga gatttctttt tgttctggga aaacaaaatg ccatgacaat
     1261 agcagcaaat aatgatactt ccgtaaggct cgccgtaaac tggggagagg tgaaattcct
     1321 atgtgcttac ccaaagcaat tcaaaaattc taatcttttt taggagatga ttttataaaa
     1381 ttgagagtct acttgaataa aaaacaaacc tgtgagtttc taggaattga taataatact
     1441 ttagataagt ggattcgtat atataatttt ccagtaatca gaattgacgg tatagttcgc
     1501 tttgacatag aggatatcaa agattttatg aatacattta aaacaatttg aaaatttctt
     1561 ctcgccgcat atactaagaa tagcgaaata tactgcctta ctttttaagg gagtgaggaa
     1621 ttttgcctac aaaactttca aatgggaaat ataaaactaa tctgaggtat ccaaaaaaat
     1681 tcagagaaat cactggaatt acatcagaaa agtatcaaaa agtatttcca actaggcaat
     1741 tggctattaa agccgaaaat gcaatgaaaa ggaaaattga aacagtttta agagaggaga
     1801 atgcaaattc actagaatta aaaggaaaaa taaaatttaa ggaattctat gaatcaaaat
     1861 ggcttcctag atatgaacta ggtcagacta ctagatcaaa aagagctcca agttacgtaa
     1921 caattagtaa tactaaagat atattccgat tgcacatcct tccaatgttt ggtgagtatg
     1981 caatgaacta tctaaattca aatactgaga taatatcaga tgaattaaca aaaaaatcga
     2041 aagaatacgc aaatataaaa attatcaaag gatatgtccg ttctatgttt gatattgcag
     2101 aaatactaaa ttatattgaa tttaaccgaa ctaccaaaat tattcaatgt atcactgcac
     2161 ctaaaaaaat tgctttagaa gaaagaagga tacgggaagg taatcaagca ttatcgtcag
     2221 aagagcttat tgcttggata gaagcagtaa acactgactt gaataatcac ttgcttactc
     2281 ttcatgacta tactcttttc atgcttaccc tatatcttgg tgatagaaaa agtgagacgt
     2341 atgctttgca atggaaatat atcgactttg agaaacaaac ggttcgcctt aaacatgctt
     2401 tggataaata tcaaaaaaag aaatttacaa aaggtcgaaa ggataccgta attcaagtac
     2461 ccgaaattgt aatggcatta ctaagcaaat ggaaatcagt gcaagctgag caattgttga
     2521 gattaaaaat taatcaaaca ccagatcagt atctctttac ctatactaaa ccatccggag
     2581 aagtaaattg ccctgttcac gctgattacc taaactatcg aatcaattca attaaaagac
     2641 gacatcctga attggctcat ttatctccac ataagcttcg tcatacctat gcaactatag
     2701 ctagacaagg cggagcaaat atgaatcaaa tatctagtgc tttaacacac tcagatattt
     2761 ctacaacgag aatatacgta aatacaccag atgtagtaga taaaactgtt tttgaagcct
     2821 ttcagagagg attgaataaa tgtgattagt atgtgttctt aaatgtgttc ttaaacaaga
     2881 aaaagacact tttcaaacaa ttgaaaagtg ccttgaaaca ttgatatata aataatatta
     2941 acgtttagag aattgagatg ctttacgagc ctttttgaga cctggttttt tacgttcgac
     3001 catacgtgcg tcacgagtaa gtaagccagc acgtttaaga gctaaacgga agtcaggatc
     3061 aacttctagc aatgcacgag cgataccatg acggatagct cctgattgtc cagcgtatcc
     3121 tccgccgttt acgttaacaa atacgtcata tgcgcctttt gtttcagtaa cagcgaaagg
     3181 ttgattgatt acttcacgca agtcagcatg tggaatgtat tcttcaacat cttttttatt
     3241 tacagtaatt ttgccagttc ctggtactag acgtacgcga gcaactgcgt ttttacgacg
     3301 gcctgtgccg atatattgaa cttgtgccaa tgaaattccc tcctattaga ttaagtttgt
     3361 gatgtctaaa acttctggtt gttgtgctgc atgtggatgt tctgctccac cgtatacgtt
     3421 caattttgta aattgtttgc ggcctaaagt gtttttagga agcatacctt ttacagaagt
     3481 ttcgatcaaa cgacgagaat ttttagcacg caattcgcca gcagtgattg atttcaatcc
     3541 tcctgggtag ttgctgtgac ggtaataaat tttgtcagtc gcttttttac ctgttaattt
     3601 cactttgtct gcattgatga cgatgacgaa atcaccagta tccaaatgag gtgtgaaagt
     3661 tggtttattt ttaccacgta gtacagatgc aacaactgtt gaaagacgtc ccaatggaac
     3721 atcagttgcg tctactacat accatttacg ttctacttcg cctggtttgg ccatatatgt
     3781 tgtacgcacg ttattttcct ccaatttaag ttctgatgtt tgacatacac ttcgagtttc
     3841 cggggctctt tgtggggcaa acaataccat ttaacatatt acccgctaat ctagtcaatg
     3901 tcaacgtttt tctgcttgat tgaaaaattt atatgaaact ttacttcttt tctttctttt
     3961 atataaaagg gtcgtttcct gtcaaaatga aaaacaaaaa gaggctgtga caaaagtctt
     4021 gtcacaaccc cttattttga ataaacggtg ttctcctgcc aactcctcgg tcacaagtca
     4081 caatatccat aaaacataag aagctgtttt ttaaaattgt ttcttgtgac tcggagctga
     4141 acggcaggct tacaacctct tggtaaacgg tgttcaatca gctgaccctc ggtattagct
     4201 caaaaaacgg caaaatatga ggaactattt tgacgtttgt ttctctaata ctcaggtcaa
     4261 aacgctgatt tcacaacctc tttttcggtc aagttcaaca acagttttta cgcgtcgatc
     4321 tctggcgctt tgcccaaatg agcttggatc atccagatac gtttttctgt ggctgttttg
     4381 aattcgataa agatatcttg tgttggatcg tcgccttctt ctccagaaac ttcgattcct
     4441 ttttggtaaa gatctgctag ataacgatag cctgcaacaa gtgtttccaa acgttctgga
     4501 atagtacgat cccagcggcc aatttcatca gggatttttg tgttatctgc aaattcacgc
     4561 aatgtagaat aaggtgaacc gtctaatgtg atcaagcgtt cggatacttc atctaactga
     4621 gcgttcaaat catccatgaa ctcatccatc attgggtgca atgtaaggaa acctggtcct
     4681 ctcatgtacc aatgtgtttg gtgaacaaca acagacattt ggcttagatc tgcaactaat
     4741 tgatttaata cttctttggt ttgttggaat ttcatctttc ttgcctccta acattttctt
     4801 acacttaaaa taatagtaga ctttcaatga aaagtacaac aaaatcattt acctgagaac
     4861 gattttcagt tcgctttttt atccgtaaag ccaatcattt ttcagaatca gctaattctt
     4921 ctcgcagttg agcaaattgc tgataagtct gtgctaaatg cttttgtgtc gaaacaaata
     4981 atggatagat tttctgatat tttttatgat cagtttcttg tactccaact tgctctttca
     5041 attctatcaa ttcctgtgct tcactgatac tttggatctt tccgatgctt ctccagccta
     5101 aaatcacagc tcctaatgcg gatgcttctg tgacagtagg gaaaacaagc gggtaaccca
     5161 gtacatcagc catcatctga cgaaaaatcg gagattgagc aaacccgcct gtagcacgga
     5221 tctctgtgag ctgattttcc tggcaaactc cttttaaaat ccgataaagg ttgagacaga
     5281 tcccttctag aatcgccttc atcatttctt tttctgtatg ttgccgctgt aaaccgataa
     5341 aactgccaaa cgcatctgcg tcccaaagcg gtgctcgctc accaagtaaa tagggatgaa
     5401 aaatcagacc attggcaccc gctggcacaa aagcgatagc cgaaagcagt gcatcatatg
     5461 gattttctcc tttttcttta gcagattgaa cgacttcctg taaaaatgta tgccctgccc
     5521 aatcaaagat gccagcacca ttgctagtcg ctcctcccac tacccaatgt ttctgatcca
     5581 gaacataaca aaacgtctcc atttctggat ggaactgagg ctgagtagta ataaaacgaa
     5641 gtgctccgct cgttcctacg gtcaaagcgg cgatcgtatc accaaaagca cctaacccta
     5701 gattagaaag cggcccgtct gcccctccca aaacaaatga tatatcattt ggcaaaccta
     5761 gttctgctgc tgtttttgat ggtagacctg ttacttgata ggtggaagga aagacttgcg
     5821 gcaattgctc tattcgaatg ttcaagtagt caagcacttc ttctgcccat tggaattcat
     5881 ggatatcaaa atatccagtt cctgaagctg ttccgtagtc gctgatcagt tcgccaaaca
     5941 atctataaaa gatatagtct ttgataccga caaaataagc agtttttttg aataattcag
     6001 gttggctgtt ttgcagccac ttgattttgt tcaatggtgt cattggatga atcggcgtcc
     6061 cagtctgccg ataaaattct ttgccaagca cggtatattt cagtttttct gcttcgtccg
     6121 ctgctcggtt atctgcccaa gtgatcattc gagataacgg tgttttctct tcatccaaca
     6181 atatcaggcc atgcatcgca gaggagaagg agacaaattg aatgattgtg tctgaaggca
     6241 actgtttaat tacttctttt ataacggtgc agacaccttg aaagatcaat tcctgatctt
     6301 gttctgccat cccttgtgtt tcttggatca aagggtagcg aaaataagcg gatgctgctt
     6361 cttgggcttc atctgtgaaa gcaactgctt tggtttgtgt ggttccgata tctaatccga
     6421 ttgaaacgtt cattttttca cctcaaattt tatgtatgta caaaaattta gtttaagctt
     6481 gcgtatcttg gttttgaaaa gggggagatg gcgtgttact ttattttatc attggttgct
     6541 gtatcggatc atttttatgt ttaaccgccc agcggattcc gttaggtcac tctattattt
     6601 atcctagatc tcattgtgtc aaatgctgtc gttcgctttc ttggtatgaa ttgattccga
     6661 ttctctcgat catcgtccaa cgatttcgct gccgctattg caggtgtcgg ttgcccttct
     6721 actatttgtt ggcagaagcc ttatgtggtg gtctttttgc ctggttcttt actttttctt
     6781 ccgcaagaaa tttttcgacg ttcatatgga tgctttcggc tttgctattt tcgttgatgg
     6841 atttatttta cttcatggtc cattctcaca cgctattctg ttcttgggca attttatgga
     6901 ttttttggtt gcaggccggc gtcttccaat ggcaaagtgt gctgttaacg tttatcgtag
     6961 gcggtgtgtg ccttcgctat ggtcaatcct atctcggagc tggcgatact ctgttgatgc
     7021 tttcttggag tggtggcttg tctctagaag agttgcttca gatcttgttt cttgctagtc
     7081 tgtttggaat atccgttttt tctgtttact ttatctgtca taaaaaaaag ttggaaaagc
     7141 tgcctttcat tccttttttg agcagtgcgt tgctgattgt ccttcatctt aggtattgaa
     7201 aaaaggttgt gacaaacgac ttgtcacaac ctctgatata tagtgttctc ttaccaaatc
     7261 cttgtgactt ggagctaggc gacaggttca caacctctcc actaaatggt gttcaatcag
     7321 ctgaccctca gtattagctc aaaatgctgg ttttacaacc tctgatatac ggtgttccat
     7381 aagtagcttt ttcggcttct tatttcttga cgccccaatg tcgacgaagg aaacctgcac
     7441 gtccagaacc ttctcgataa agattgtaat ggagcttgtt tttcttgtaa taatcctgat
     7501 ggtaatcttc tgcaggataa aattcgcttc ttggttcgat ttttgtcacg attggcttat
     7561 cgaatcgccc gctgtcttgc aatgcttgtt ttgaacgctc tgcaatattt cgttcttctt
     7621 catcattata gtagatcact ggacgataag aatcaccgcg atcagcgaac tgtcctaatg
     7681 cgtcagtcgg atcggtttgc tgccaataga tttccaccaa ctgatcataa gaaataactt
     7741 ctggatcata ttcgatctct actgcttctg tatgccctgt tgtgcctgtt gttacttgtt
     7801 cataagttgg atttggtaca tgcccgccag tataaccgga tgtcacagaa atgatccctg
     7861 gctgctcttc aaatggtttg accatacacc aaaagcatcc gcctgcgaaa actgcttttt
     7921 ttgtcatata aaatccccct tttttctcat cataccttga tttccaaaag gaggataacg
     7981 ttttgcttgt gacagaaaaa acggaaacta ttatatacgt gatacggctt ctgataaatg
     8041 ccaaaacgaa cgtacttgat caaaaacggt taaatcagga atcacatatt cagcagaagg
     8101 aagatttatg ttttcaccta ttcccaatac atgcatgtta ccagccaaag ctgcttgaca
     8161 accagcttct gaatcttcaa tgaccaagca tgcatttggc ggtacattca attgctgtgc
     8221 tcctttgaga aaaacttctg gatcaggttt tgcttttgat acttgcgtgc cgtcaataag
     8281 gacatcaaaa taacttgtca aattcgtttt ttctaaaatg aggcgtgcat ttttgcttgc
     8341 tgatcccaat ccgatcttga tgtttgtttt tttcaagtac tcaagaacag ctattgcacc
     8401 aggcaaaacg gatgtttcat ccattttttg aatcgcttga agatatagat tgtttttttg
     8461 ctcagcaaag gctgatttct ctttttctga gaatttctgt tccatttttc caaatgacag
     8521 caatcgctct agtgactcgg ttctggatat tcctttcagt tgctcgtttt ctttctcagt
     8581 gaatggaatg gacagctggt tagctaaaac cagccacgct tcgtaatgat aacgagctgt
     8641 gtctacaaga acgccatcta aatcgaatag tgctgctttg attttcatcg attacctcct
     8701 tgaaaatgaa cgacttgaag taaagatgcg atgtttttag ctgtgcgatg aagattatca
     8761 gtggcttgct gtaaagcttc ttgtaaaggc acagctgcag gaaggatcgg aaaaacggcc
     8821 gaaatgccaa catctgctgc tttttcgctt cctttaccaa cacttccgca aatagctatc
     8881 acaggaacgc cctctggtac tcttctagca atcccaactg gcgcttttcc ttttagactt
     8941 tgtccatcta gacgtccttc gcctacgatt acgaggtctg cttgctgtac ccgtttatcg
     9001 aactccagta aatccaatac gtagtcgatg ccagagacta ttttccctga agcaaatgct
     9061 aacagtcctg cacccattcc accaccagca ctactgcccg atgcctcgat tacttgaggg
     9121 gcaaatctca tataaaaatc atgcatggct tggtcagcca ctgctaattc attttctttc
     9181 aagccttttt gtggtccgaa aacaaaagaa gcgccttctt ttccgcataa aagattagta
     9241 acatcagtaa tgacagtgat tttggcttta atcagctcaa taggcacgtt cgttttatca
     9301 actgtagcaa ttttacctag attttctccc agtgcttcta ctttttgatt atcttgatcg
     9361 taaaaagcat aacctagacc ttctgccatg ccgatgccgc catcgttggt actacttccg
     9421 ccaacgccga tgatgatgtg tcgaacacct tgttgcaaca attgtcgtat cagttctcct
     9481 actcctcgcg tggataacct aagtggctgt tgttggttta gtgggacatc tttcaatccg
     9541 acgatttctg ccatttcaaa aatcgcagtt tgaccgtctg aagcgtactg gatttctttg
     9601 tttttgccaa atgcattagt aacgactgct gtttgccgct tcaaccttaa actgtctgct
     9661 aatgatgaaa ccgttccttc tcctccatcg cctataggta gcagatcata ttcagcctga
     9721 acaaaaactt cttgaaaacc tgattgaatg gcttgtgctg cctctaaggc tgtcagactt
     9781 tctttgaaag aatctggcgc aatcagaata cgcattattt tcccctccgt tccaagatca
     9841 gttctttttc cagctggtat tggtctccat tgacaaaaat aggtaatgtt tctttcgtct
     9901 ctttttttat tactatttgt ttttttgtca aaacaaatag caacctgtga tttttccaaa
     9961 taaaaggaaa agaaattttt tcccatgctg aaggaagtct tggagaaata gaaagagttc
    10021 cattcgttac tgtaatacct gaaaaaccaa atataactgc tagccatagt gctcctaatg
    10081 aagcagcatg aattccgtca tctgatgaat gcggatctgg tcctaaatca atcaggcacg
    10141 cttcttggaa taaatgatac gcccattcca tttcttggat acggcaagcc tctatggcgt
    10201 gaatcgcttt actcaacgat gagtcgtgga ttgttttgtt ttcatagtaa tgcaaattct
    10261 tagaaacgat tggttgagaa aaatactcag gtaataagta taacagcatg acaagatctg
    10321 cttgcttgct gacttggagt tcatttactt cgctacgggc ataatcaagt aaaatagact
    10381 ggctgccagg acgttctttg taagtggtca aatcaataac tggcttactg agatacgtgt
    10441 catcttgcgg aatcagctgt tctttgttag gcactggcaa atataactta tctaaaaaat
    10501 tttgacattc tttcaaaaaa agcggatcgc cagcttgata tttaacagct aaggccacat
    10561 tataatgcgc cagatagttc gtatatgcat tattgtcgat atattctgtg tattcatctg
    10621 gaccaatgac tctgtgtatc tctaaatgat catcgacttt tacagctctg ctcagccaaa
    10681 aagctgctgt ttcatgaatg agcgtttttc cctttgtttc taaaaacgat tgatcctctg
    10741 ttgcttggac atactcttga acggcataag caaggtctgc actgatatga tgttctgcgg
    10801 cagctgaagc aacttcttgt cttgttccgg ttttgatatt caatgcagca aatttgggtg
    10861 tctcttcctg accagtgtgt gcgctttccc atgggaaaag tgcaccttga tagtgataat
    10921 ctcttgcttt ttgccgtgcg ccttctaatc gatcataacg gtacagcagc aaattctttg
    10981 ctacttcagg aaactgatat aaaaagaaag gcaggataaa aatttccgta tcccagaaaa
    11041 catgcccttt ataaccttcg ccagttagtc ccttcgcccc tacactaaca cttggatcat
    11101 tgcggggagt cataatctgt aaatggtaag cagcgaagtc catcgctaac tgatcgaaag
    11161 aagaatcgcc ttggatcgtt atccgatgct gatgccaaaa atctgtccaa taagacatcg
    11221 actgctctaa aatttctgta taactaacgc ttttctgggc ttgggcaata cttttcttaa
    11281 acgggtctgt ttgctgaaga gaggtagaga gcacgatgat cttctccagc gtaaaggacg
    11341 tattttttct gatcttttct gaaaaggaag cggtgatccg gcgatttttt gcttggaata
    11401 cacctgcttt attgaattta gctgcaatcc caatatcaat tttactttct gttgtctggt
    11461 aggatgcact gatcaaatcg tcaccaaata ctcgcagttc tttttcaacc aactgctgtg
    11521 taccaaaatt ggtttgctgt ccatcgatac ccgttttcac atctacttgg cagtcttcgg
    11581 tcaacggctt gatgaccact ttcagggctg cctgatggag attattttga tcagcaacac
    11641 gacaagtaat gacttccact ttttttcctt gagcagtttc aatgagcgca tagcgtttaa
    11701 gctctcccat ttctaaatct agtgcccgct cgtatgcaag aactttcatc gtctcaagag
    11761 aaaaatgttc accgtcgatt tttatttccc atctgatgac atctgggaga ttcactaact
    11821 cggctgattc tgctcctaaa ggtcggttat atacaccagc tgcaaacatt ccccttactt
    11881 gattccgata gtcttcctcc tggcttcctc tgataccaaa aaatccattt ccaatggtca
    11941 tctgactcgc atacttattg atatactcta aatcaaactg tttttcttct actttcataa
    12001 ggtaataact tctcctgttt ctgccgaacg atataaattt tccaccagat tctggatgac
    12061 atatccttgc cagccatctg caatcatctg agtctggtca ccgagcgccc gattcacaaa
    12121 atgagccata cttagttcat gtgggtcatt aactggcgtg gtcttttgta aggaaaccag
    12181 ctttccatct acatcttcga atagttcgcc tggatacaga ttagcacctg cctgatcgcc
    12241 acaaaaagcc acattcagtt tgtcttctct gatattcaaa gcaaacgaag tattcagttg
    12301 gatgatcttg ccgttttcta attccagtgt gccaaaaatt gcatcttcta ctgtgaattt
    12361 gcttggatcc catttcccga atttccctga attttttttc gtaccaattt tttggaagct
    12421 gtacgcccga acgcttttta ctttaggaaa tccagtaata tacatcgctg tatcaagcat
    12481 gtgaatgcca taatcgatca aaggcccgcc tccttgaagt tctttgtcga taaacgttcc
    12541 ccagcctgga acaccagacc gacgaagcgc attcgcttct acgtaataaa tatccccgag
    12601 aacatcaaga tgattcttga tcattgttgc ttcgtcagaa aaacgatgct ggaatccata
    12661 agccaaaatc tgcccgtttt tatcggctgt ctctgccatc tttcttgctt gatcagctgt
    12721 catagctggt ggtttctcgc acatcactga agcattagct tcgagggcag ccaatacatg
    12781 ttcgaagtga aagcgattgg gtgtacagac actcacgata tcgggagaaa tctcattcag
    12841 catttgtgta actgatgtat acgcatgaga aaatcctgta cgtcggcaaa agtcttctgc
    12901 tcgctggctg actggatcaa ccacagcggc caattctaag acatctgatc ttttttgata
    12961 ataagcagca tgtacttttt ctgctacttg tccagcgcct atgattgcta ctttcttcat
    13021 ttatttctct ctcctttgct tatttactta ttgttattct ttctctattc tttctctaaa
    13081 tcatttaaat gacgcgctgt ttccagacag tttttcaagt attgcaatga ttcctgataa
    13141 attttcactt cattttctcc tcgcaaacga cattcatata ccatataacc ttcatactca
    13201 ttttgaagta gcgtttgaaa atggcgagta aaatcaattg cgccagatcc tggttggtag
    13261 cgatgattat ctgctaaatg gatatgaccc acatactctt tttgcgtagt caatgctttt
    13321 gaaatatcat cttcttcaat attcatatga taaaaatcag cgatgatctg cacatgtttc
    13381 aattgattag agtcaatgta atgacgcgca tccgctaaca aattgatcat atggtcttgg
    13441 tatcggttca aaggctccaa ataaataacc gtacctgttt cttcggctac tttatctaaa
    13501 taacgaagtg attcgctgac tgctttatag tctccttctt tgcttcgggg tgaaaccatc
    13561 ggcggtaatc gataagtgaa cattccccaa gctgctggga taacgattcc tttgcctcca
    13621 acctcgctta gtgcacgcaa aatctcagca atttgacgta caccattaag acgccgttct
    13681 tcgataaagt caccgatcca cccatcgtag ccgttacaag ctgtcactac tgggatccct
    13741 gtttctttga ttgcctgttt gactgtgtcg atattttcta ttaacaactt accgtcgatt
    13801 tcgtattctt caaatccaca gtctttgata aatctaaatt tttctaaaat gtctcttggg
    13861 aaaaatgctt gatcttgcgt accgaatttc attgttctcc tcctcggact tgaacgccca
    13921 ttttgatact ttcttctggg tgctggtcta cataacgcat gtaagcttct gcgctttctg
    13981 caaatggcac aactggatca atgatttctt cacaatccaa gtaaccgttc atcaataatt
    14041 cccaacatgt gtcctcgatt cgtttacggt tccatcttgg gtaatctggg tttggttcac
    14101 tagatgctcg agcaaagacg atttttgcat tattgaaatg tgcttcgcga ccaagattaa
    14161 acccagctgg aaaaggttta gcaaaggcaa cataagaaat gatcccgcca tagccgatcc
    14221 ctcttaaaga agcttgtaat gcggcagcac tgccactcgt ttcaataact gaatctactc
    14281 cacgtttatc tgtcaattcc tttagacgaa aaccgacatc tgctttcata ggatctagcg
    14341 tgtaatcggc accgtatttt tctgctaatt ctctacgctg cgctatggga tcgatcccaa
    14401 cgatggtagt agcacctgct tttttagcta attgaatcgc aatttgcccg atagcgccta
    14461 aaccgaagat tgctacagca tcacctgctc gaacatgtgc ttcccggata ccacctaaag
    14521 cgaattgagc aggatcgtaa catactgcat ttttccattg atccaaccga tcaagtttac
    14581 gtagtttata attatcaaca ccgtttgtaa tcagcgtttc acgaatgggt ccataagtgc
    14641 agactaactc tcctttttga tactctgtca ccaaactgcc cgtttcttcg atcgtaccga
    14701 caatcatatt tcctaattga aattcgccaa ataccacacc gcgttggctt ccttcttctc
    14761 ttggcaagaa taggcgccat tcttctgaaa attcttcatc gataaatgga cttaatcctc
    14821 taaagtcgac aatttctgtt cctggttttg gagtagcgaa aattactcgg atacgtactt
    14881 cgttcttttc gatctcacgg tcttcgtaat ctttgaatcc ggctattctt ggttctaatg
    14941 caactaattt tttcatcttt tctttcctct ttcttttctt tttatccttt tacgccgcct
    15001 tcgactaaat cacctttaat aaatcgttca gataacgcat acataatgat gactggtaaa
    15061 gcggtcacca atgaagcggc catcattcgt ccccaaatgt agtctggtgt actgaataat
    15121 gtgttcaaac cgattggtaa agtaaatttt tcggaggtcg acaggaaaat cgaagcaaat
    15181 aaataatcat tccacgaaac cataaagcaa taaacgaaga cagaaatgat tccagaaata
    15241 gccaatggta taatgatccg aataatgatc tggatccggc taagaccatc gatcattgct
    15301 gcttcttcaa tatcagtcgg aatcgtgtca aaataacttt ttagcatgaa tatcgcagta
    15361 ggaagtgttt gaacgaccat cgtgataatc agtgctgtat tggtatcata caaacctaga
    15421 ccggaaatga ttttaaataa tggaacaacg atcaaaatac cggaaaacat ataaacggtg
    15481 taaaagctag cattgatttt cgagcgagct ttgaagcgta gttttgacaa agcgtatgcc
    15541 ccgctgatcc caatcactac tgcagttacg gaggctatca aggagatcac taaactattt
    15601 ttgaaataca tgatgaatgg aaaaatctca gcattgaaaa tatcctgata atgttcaaaa
    15661 gtccattctt tcggaaaaat agtttgtgtc gttgcaattg cttcttgtga atccttgaat
    15721 gatgtcatca gcatgatcaa aaatggaaac aaattgacag ctaatagcaa caaaatcgtc
    15781 gcgtaaaata agattttcct gctcttttta tttttcattt caagtccacc ttctttcgtg
    15841 agagcaagac gaccgctgca ataatgatga acaatagaat cgatatagct gctgcttttc
    15901 caagatcatt gaacgcaaag gctgtctgat acaaataaac gcctaagata ttgactttat
    15961 tcgtcagtag atagacatct gtaaacatat agaacatcca gatagatcgt aaaacaatca
    16021 cagttgctag tactggtttg attgccggca gtgtcacgat cttgaacttc tgccaagcat
    16081 ttgcaccgtc catttcagct gcttcataaa gcgttttgtc gactgtttgc aaaatagcca
    16141 aaaatgaaat aaacgcatac ggatagtatc tccagatagc aaacaaaacg accataaaga
    16201 agctagcaac tggctggtcg aaccacagcg gtgcttcgtt gaaaagctgc aacctatcta
    16261 ctaacagatc attgacgatt ccataactat tattgaacat atatttccaa gcaaaaatca
    16321 aagaaataga tggcgtaaca taacttaata aaatcagtga acgcaccgtt ttcctaaatc
    16381 tgaacttgcg gttaagcaaa atagctacgg ctaatcctaa agctgtactg cctgctacaa
    16441 ctaagaatgt gtaagcaact gttaaaccta aagaacgata aaattcacta tcacttaaaa
    16501 tttcaagata attgcttaat ccgataaaaa cggcgtctga gttaggattc agcggcatat
    16561 cgaaaaaact gatctgaata ttggaaagca ttggaatcag cactaaaaca gctaataaaa
    16621 gcatgcttgg tgctaaaagt cccatggcta attttaagtc agaatgtttc cttggacgat
    16681 tcattgaaac ctccccctga taatctgcca atagctatct acttttttcg aacaccattg
    16741 gcagaacttc ttgttatttc gtattttttt gtgcgtcagc taaagcttga tcgacatctt
    16801 cgtttccgac agttacttgg ttcactgctt ttccgatcac acctgagctt gtgatatctc
    16861 ccattttcgt gaaattcttt tccccgacta gtccaaagac ttgtacttca tcaaaagcac
    16921 tagcaatctc agatggcagc tcgccaaaag acttgatgac ttcattttct ttgtaaccat
    16981 ccagttcgac tacttgttta ttcactggtt gagcaccacc aggagacatc aagacccact
    17041 tttccatgtt tttcggttga gataagaaag ctgtgaatgc ttcagcagcc tctttttgtt
    17101 tctcgtctag accagaagaa atcgtcaatc cagatactgt gccatagaca gcttgatctt
    17161 tttgtgttgg gatagcaaaa ccgatatttt ctgagttccc cgcttcataa acagaaggca
    17221 aaatgtaagt tgaatagatt gccattggtg ctgttccatt catgaaagca tctttgattt
    17281 ctgtcacatc attagagcct ggcatcgtgt attgggataa gttttgataa aacgacaatg
    17341 cttctctcat cttttccgta tcgatcgtta cctcgccttc atcatccaaa acatttgctc
    17401 catttgacaa agcaaattga gagaacgctt gctcactcat tgttccttca gcagtaggca
    17461 tagcaattcc atattgttta ttctctttat ctgtgaaatg ttgagcaatt tttaaaatat
    17521 catcccaatt ttctggttct gaaaaaccag cttctgataa tttttctttg tcataccaaa
    17581 taccttgaac ccagccgcta attggtgcag caatatagct ttttccatct tctgaacgaa
    17641 caaggttttt ggctccgtca taataattat cttctccagc ttcctcgata acgttttgga
    17701 ctgccgtctg atcaatcagt tcatctttat ccatcacttt agcaaaatcc tgactgactt
    17761 ccattacttc tggtaattta ccggaacgag ctaacgtaac gatttttgta ttgaacgctg
    17821 attcttctac cggcacttgc ttgattttga tgtctggatt ttctttttca aaatcagcaa
    17881 ccagttcatt gatcacactt aatcgttcct gttcgacaga agagtgcatg aattgaatcg
    17941 ttgtctgttg tgattcgtta gagctttgac tttcaccaca agcagtaaga agaaatccag
    18001 tagctagcag acaggtagta acaataattt ttttcatttt tttccacctc ttattttatt
    18061 attttcagcc acatatattc atacggctgg aatatcaact ttcgttcttg actgcaatgg
    18121 ataatttgtc cagaaaacag gtctaggtaa tctccttttg gtaaaagata acctgctgat
    18181 tgattggaaa aattatggat aactaagact ttctcttcct tcgcttcgcg aataaaactg
    18241 ataaaagaat ctgctgagtc cagtaagtaa atcaaactat tcggatggaa ggctttttct
    18301 ttttttcgaa tagatagcat ctgggtcaat tcaccatata ctgctgttct taatggatct
    18361 gtctgcaact ctttctcaat atctgctaac aaaaattttt gccgattgat ttttcgattc
    18421 tctcctgttt tttctacgcc tttgtaatca tttcgacttc ccagcacact ttgaatataa
    18481 attgccggca cgcctggtaa cgttaccaaa aatgaatgag cagctaaaaa gcgtttgctt
    18541 ctccattccg tcgtatctgt tggagaactt aacgcatcta gatacgtagc gtttatctca
    18601 tatggactgg tcgttccatc tgggtttttc ttgtagttta ctcgggcacc ctctttcttc
    18661 agctgttcca ctaattcaag gatcgttttt tccggcagaa tacctcgtac cggattcaat
    18721 ccgataccgt catgggaggc taaaaaatta aaaaaagttg tttttttcga tgcgaaatcg
    18781 atggttttta accattcttt caacttactt gtattacccg aacgaatcgc ttgaagggtc
    18841 aaaggtggta gcgaaaactg atagaccatc tgtgcttcat tctcgccatt cccaaaataa
    18901 ctgatattat ctttgtgtgg cacatttgtc tcagtgatca ataccgttcc tggagctgct
    18961 tcatcagcga ttgcacggaa taattggatg attttatgcg tttctggcag gtgtatacaa
    19021 gaagttccta gttctttcca taaaaatccc acagcgtcca agcgaataaa tgaagcgcct
    19081 ttttctaagt aaaacaaaag aatatcgatc attttcaata aaacttctgg atttttaaaa
    19141 ttcaagtcta cttgatcttc gctaaaagtc gtccatacgt gtttttcttt cccgtttttg
    19201 tcaatgaacg ttgtaagtaa cgggctggtc cttggtctag tcacgctgct tgtatctgta
    19261 tccagtggca aatcaataaa aaaatctttg tacgtatcat tcaagtttaa atattcctga
    19321 aaccaagtac tttcggcaga catatgattg cagacaaagt cgaacattaa ccgtgtttcg
    19381 cttctcattt cttctatatc ttcccatgtg cccaaacggt cgttgattgc ctgataattt
    19441 acaacggaga aaccatcatc agatgtatat gggaaaaatg gcaagaaatg tacaactcta
    19501 aatgtatctg ccaaatactt ttgataaaat ttcttaaatg tacgcaaagt tggttgctgc
    19561 tcttcaaaaa attgatcccc ataagtaatc aagaaaatat cttcttcgtc ccaatgcagt
    19621 ttgcctgcct ggcctttctt ctgctgataa acactgactt tttgttcaat catagaggcg
    19681 gttttctcag acaaatctga gtcgcgataa atcgcttgta aaagttttgt atacatcgga
    19741 ttcccctttc ttttttggga gcgttcccaa cgatttgatc atattatgga aaacgcttac
    19801 tgtcaatagc atttttttaa ataattttga tatacacaaa aatacaaata agaaagctta
    19861 tgtatcaata attaatagct tcttaaaaaa atatggtctc tcatgatcat gcaagctatt
    19921 cctaaatttt caaaatcata gacaaaaaag aatgtctatt gtactatgga attattctaa
    19981 aacgctccca aaaaggaggt gcatataaaa ttgaaaccta ctatttatga cattgcgaaa
    20041 aaagctaatg tctcaaaatc aactgtctcc agactattaa ataaccagcc aaatatctct
    20101 gataaagcaa aagcaagtgt acttcaagca atcaaagaat tgaattatga accgagcaaa
    20161 attgcaagag gactgtcagg aaatggtttt gacgcgattc tagcattatc tcatcgtact
    20221 tctcatacga cctatggcaa tccttttttt tcagatgtta ttcaatccat ttctgccgtt
    20281 tctgaacaaa ataacttcga cttgattcta caaacggcaa aaacaccaga agaagagcta
    20341 gaaaaatgcg cgaaaaagat ccaagaaaaa atgatccgag gaattattat tttaagctct
    20401 acgatggatg aaacacttct ttttgaattg gatcaataca atattcctat tgtggtaatc
    20461 ggaaaagtcg gaaacgacta cacgaacatc tactcagtgg acacggataa tttccaggat
    20521 agttacgatt tggtggaaac actgatcaag aatggacacc gtcatatcgg ctgtctccat
    20581 gctccgacag aagtttatgt atccaatgat cgtctcaatg gttaccgtca atgcttattt
    20641 gatcaccacc tagatatccg taatgaatgg attatagacg gcggctttcg cttagaagat
    20701 agcatggcag caatgaatga tttaatgaag ctacgagaaa gaccaactgc gattttttct
    20761 accgatgcat taaaatcatt gagtatttac aaagtggcag aacaatctgg aaagcagata
    20821 cctgatgatc tttcgatcgc aggattcagt gatcccttat tgtcctccct attttcgcca
    20881 cagttgactc ggatagacat tccgacaaat cagttaggaa tcaaagccac agaactttta
    20941 ttccaactaa tccaccacca ataccctgaa gaaaaaagaa tcattctttc aaccgagatt
    21001 actctcacag attcgatcca acaacaagaa atgtagaaca gaattataaa agaacagaaa
    21061 cactgaggat aagtcagtta ctctgttctt ttttcaatca ctcatccctc gttaccccct
    21121 cccggtattt tagcgaattt ttcttatttt ccatctgttt tagatagctg tggataacta
    21181 taatgtttgt gttaaactat tttttccaca gggaagaaaa aactattttt aaccacgttg
    21241 tgtataagtt tttatagttc gtttttttaa acacatttac ccttatttca atccatgtta
    21301 tttggggata cttatctcta aaacataaat agaataacag acatgtctac tggttttgtt
    21361 ttattcgagg aattattcaa taatagctag caaaatatta aaaataaccg ctctatcttc
    21421 ccatcaattt attttgcatt caaaaaatga tctatcttta cttttgttga ttgacttctc
    21481 ttggaagatg atcgttccga taccttaatt ggatacgaac cgatgttgtt aagatccttt
    21541 cccacttttc ttctagttag acaaattatt ttagacaaac caaaaaagag gttgtgacaa
    21601 taatttgtca caacctcttt tttaaaatat ctattttgtt tgattgttca ttgcgtcttc
    21661 tgcagccatt tgcgcttcaa tatctgaaat actgtagaca ttttcgcttg ctacaccgac
    21721 ttcttttggt tccatgtcac gataacgttg cataccagta ccagctggga tgatcttacc
    21781 tataataaca ttttctttca aaccaagaag aggatctttc ttaccgcgga tcgcagcatc
    21841 cgtcaagaca cgagttgttt cttggaatga tgcagcagat aagaaactat ttgtttctaa
    21901 tgatgctttt gtgataccta gtaagacagg tcgagaagtt gcaggaacgc ctcctgagac
    21961 tagcgtattg tagttttgat ctttaaagtc tgcgatgtct aataatgtac ctggtaagat
    22021 atctgtatca cctggatcca ttacacgaac tttacgcagc atttgacgaa ccattacttc
    22081 gatatgcttg tcgccgattt ctaccccttg catacggtaa acacgttgta cttcacgaag
    22141 caagtagttt tcaacagata atacatcgcg aacttgcaac aattgttttg gatcgattga
    22201 tccttctgtc aatggtgcac cacggtggat catatcgcct tctgctactt tcatacgtgc
    22261 tgtataagga acagtatacg tacgtgtatc tgtttttcct ttgattgtta cttctttggt
    22321 acgtgttgca ggatcttctg agatatcgat gacatcccct gttacttctg tgatcactgc
    22381 ttgccctttc ggattacgtg cttcaaagat ttcttggaca cgaggaagac cttgagtgat
    22441 atcgtctccg gcaaccccac ctgtatggaa tgtacgcatc gtcaactgag taccaggttc
    22501 accgattgat tgagcggcga tcgtaccaac tgcttctccg acttcaacgt cagagccagt
    22561 tgcaaggttg cgtccgtaac aatgtttgca gacaccatgt tttgtattac atgtgaagac
    22621 agaacggatt gtcactgttt cgacacctgc atcaacgatt tgttttgcga tgtcttcgga
    22681 aatcaattgg tttcctgcaa tgatcaattc atttgtttca ggatgacgta cttctttacg
    22741 ggtgtaacgt cccactaaac gatcttctaa tgattcgatg atttcatttc cctcgcggat
    22801 ggcttggatt tcaagacctc ggtcagtacc gcaatcttct tcacggatga ttacatcttg
    22861 ggccacgtca accagacgac gagtcaagta acctgaatcg gcagtcttca aggctgtatc
    22921 ggtcatccct ttacgagccc cgtgagttga gataaacatt tccaagacgg atagtccttc
    22981 acggaagttc gaaatgattg gcaattccat gattcgacca ttaggagcgg ccatcaaacc
    23041 acgcattccg gcaagctgtg taaagttgga aatgttacca cgagctccag aatcagacat
    23101 catgaagatt ggatttttcg cttccaaacc ttccatcagt ttttgttgga tgctgtcttt
    23161 tgcagcattc caaacagcaa tgacacgttc ataacgttcg tcatctgtga tcagaccacg
    23221 acggaattgt tttgtaatag tttcaacttg tttatgggca ttttcaatga tttcttgttt
    23281 ttcattcagt acactgatgt cagcgatccc tactgtgata ccggcatgtg tcgaatgttt
    23341 gtaccctaag tctttcatac ggtcaagcat cttagaagtt tctgttactt tgaatcgttt
    23401 gaagacttct gcgatgatgt ttcctaagtt tttcttcttg aacggtaata ctaattcttg
    23461 ctctttgata tgtgcaggaa tatcagtacc agcttcaaca aagtatttgt ccggtgtttg
    23521 gacggtcaag ttgaagtctg ttggttcatt cagataaggg aattcaggag gcatgatctc
    23581 gttgaagatg atcttaccaa ctgttgtgat catcgtacgt tctttttgcc attcagtaaa
    23641 tggtttttca cctaatgagt tagggttcac accgatacgt gaatgtaaat gaacatatcc
    23701 gttgcgccat gcgataacgg cttcgttttg atctctgaag accattcctt cgccttcgcg
    23761 tccttcttct tccattgtca agtagtagtt acctagaacc atatcttgag aaggagtaac
    23821 aactggttta ccatctttag ggttcaagat gttttgagca gctaacatca acatacgtgc
    23881 ttctgcttgt gcttcttcat tcaatggaac gtggacagcc atttggtctc catcgaaatc
    23941 ggcattataa gcttcacata caagtggatg caaacggatt gcgcgtcctt gtactaaaac
    24001 tggttcgaat gcttggatac caagtcggtg aagcgtaggt gcccggttca gcaatactgg
    24061 gtgttccttg attacgtctt ctaaaacatc ccatacttcg tcttcttgac gttcgatttt
    24121 acgtttcgca tttttgatgt ttgaagctag ttcgcgttga acaagctcac gcatcacgaa
    24181 tggtttgaat aattcaatgg ccatttcttt tggaagtcca cattggtaca tcttcaagaa
    24241 aggtccaaca acgataacgg aacgacctga gtagtcgaca cgtttaccta gcaagttttg
    24301 acggaaacga ccttgtttcc ctttcaacat atgagaaaga gatttcaatg ggcggttacc
    24361 tggtccagta actggacgtc cgcgacgacc gttatcgatc aatgcatcta ctgcttcttg
    24421 cagcatacgt ttttcatttt gaacgatgat tccaggtgca ttcaagtcta acaaacgttt
    24481 caaacggtta ttacggttga ttacacgacg gtaaagatca ttcaagtcac ttgttgcaaa
    24541 acgtccacct tctaattgaa ccattgggcg taaatctggt ggaataacag ggataacgtc
    24601 cataaccatc cagcttggtt gatttcctga agcgcggaat gcttctaaaa tatccaaacg
    24661 gcggattgca cgtgtacgtt tttgtccttg tgcagatttc aattcttctt tcaattcggc
    24721 tgcttctgca tctagatcaa cattatcaag taattgttta atcgcttctg cacccatagc
    24781 agcttggaat tcttgtccat attgttcacg tttttcgcga tattcgcgtt ctgtcaacaa
    24841 ttgttttttc tctaaattcg tatttcctgg ttcgatgact acatatgaag caaaataaat
    24901 gatttcttcc aaagcgcgtg ggctcatgtc taatacaaga cccatacgtg aaggaatccc
    24961 tttaaagtac cagatatgtg aaacaggagc tgctaattca atatgtccca tgcgttcacg
    25021 gcgaactttc gaacgagtaa cttccactcc gcatcgatca caaacgattc ctttataacg
    25081 gatacgtttg tattttccgc aggcacattc ccagtctttt gtaggaccaa aaatccgctc
    25141 acagaacaac ccttcgcgtt caggttttaa ggtacgatag ttaatcgtct caggtttttt
    25201 tacttcaccg taagaccagc ttctgatttt ttcgggagaa gccaaaccta tttgcatact
    25261 ttcgaattta tttacatcga tcaaaagggg ttccctccat ttcatttaat ggcaaaccgc
    25321 aagacggctg atcttcgacc gccttgcagc tcatagaccg gattagtcta aattatcttc
    25381 tgcggtttca aagttttgga tgacatcgtc tttttcatct tccacttgtt cagcagcttt
    25441 cttttctaat tctttggcag tttgctgttc ggcaaatttt gtcaaagcat caacagtgat
    25501 caaatcgtcg tcttcatcgt ccatgtcgcg aagttcgatc tctgtttctt cgatatccaa
    25561 gacacgcatg tccagaccta gtgattgcaa ttctttcacc aatacgcgga atgattccgg
    25621 tacacctggt tttggaattg gttcaccctt gacgattgct tcgtatgttt tcacacgtcc
    25681 gactacgtca tctgatttgt atgtcaagat ttcttgtaaa gtataagccg caccgtaagc
    25741 ttccagtgcc catacttcca tttcaccaaa acgttgtcca ccaaattgag ctttacctcc
    25801 caatggttgt tgtgtaacca atgagtaagg tccgattgaa cgtgcatgca atttgtcatc
    25861 gaccatgtga gcaagtttga tcatgtacat cacaccgaca gacacacgtc catcaaatgg
    25921 ttcacctgta cgtccgtcgt acagaacagt tttcgcatcg ctggccatac cggcttcacg
    25981 aactgtttcc catacgtctt catcacttgc accatcaaat actggcgttg ctacgtggat
    26041 acctaactga cgtgcagcca tacccaagtg taattccaat acttgcccga tgttcatacg
    26101 tgaaggcacc cctaaaggat tcagcatgat atcgattggt gttccatcag gtaggaatgg
    26161 catatcttct tccggcataa tacgggatac aaccccttta tttccgtgac gaccggccat
    26221 tttatcccct tcatggattt tacgtttttg aacgatataa acacgaacta acatgtttac
    26281 gcctggtgac aattcatctc cagcttcacg agtaaagatt ttcacatcgt gaacgatacc
    26341 gccgccgcca tgtggtacac gtaatgatgt atcgcggact tcacgagctt tttcgccaaa
    26401 gatcgcatgc aatagacgtt cttctgcaga taattctgtt accccttttg gcgtgacttt
    26461 ccctacaagc aaatcgccat cttggacttc tgcaccaata cggatgatac ccatttcgtc
    26521 taaatctttt aatgcgtctt ccccgacatt agggatttcg cgtgtgattt cttcaggtcc
    26581 taattttgta tcgcgggctt ctgattcata ttcttcaata tggatagaag tgtatacgtc
    26641 atcttttacc aaacgacggc tcatgatgat cgcatcttca tagttgtacc cttcccaagt
    26701 catgaaacca actaaaacgt tttggcctag agccatttcg ccttgttcca tagatggtcc
    26761 gtctgccaga gtatcccctt tttcgacttt ctcacccaaa tgaacgattg gacgttggtt
    26821 gtagcttgtt ccggagtttg aacgacggaa ttttgttaca tcgtatttat ctaatgcacc
    26881 gttgtcgcgg cgtacgcgga tttcagaagc atcaacgtat tcaacgacac cgtcatgttt
    26941 acataacaaa gcagctcctg agtcatgcgc tgatttgtat tccataccag taccaaccca
    27001 tggtgcttga ggattgatca acggcactgc ttgacgctgc atgttggcac ccatcaaggc
    27061 acggttggag tcatcgtttt ccaagaaagg aatacatgct gtcgcaacgg caactacttg
    27121 tttaggtgat acgtccatgt agtctacttt atcaatagat acttctaagt tttcactttg
    27181 agcacgagcc ataacaacgt cttgagcaaa tgttccatct tcattcaatg ggctgtttgc
    27241 ttgggctacg atgtaatggt cttcgatatc agctgtcaag tagtcgattt ggtcagtaac
    27301 acgacctgtt tcacggtcta cacgacgata aggtgtttcg ataaatccga atttatttac
    27361 tttcgcataa ctggacaaac tattgatcaa cccgatgttt gggccttcag gagtttcgat
    27421 cggacacata cggccatagt gggagtagtg aacgtcacga acttcataac cggcgcggtc
    27481 acgagtcaat ccgccaggtc ctaaggctga aagacgacgt ttgtgtgtca attcgccaag
    27541 agggtttgtt tgatccatga actgtgacaa ctgagaagaa ccaaagaatt ctttgatact
    27601 tgccacaact ggacggatat tgatcaattg ttgaggtgtc aatgtttcag tatcttggat
    27661 cgacattctt tcacgaacca cacgttccat acgtgctagc ccgatacgga attggttttg
    27721 taaaagttca ccgactgaac ggatacgacg atttcctaag tggtcgatat catcgacatt
    27781 gccgatacct tccatcaagt tcaagaaata gctcattgaa gcaatgatgt cggctggacg
    27841 aaccgttttt acagctgctt ctggatagcc gtttccgatc acgtttactt cacgttcagg
    27901 gtctcttggt gaaaatactt tgatgacttg gacagtcatt ggatctgtga ccacaccgtc
    27961 ttctgatgga tagtaagtca ctgaatttag gccattatca atgaaaggag ctagtgtttc
    28021 catgacttgg tgagtcagaa ctgttccttt ttcaacgatg atctcgcctg tttctggatc
    28081 aactaatgtt tcagctaatg tcagattcaa tagacgtgtt ttcaaatcta attttttgtt
    28141 tactttgtaa cgaccaacgt ttgctaagtc gtaacgtttt ggatcgaaga aacgagcatt
    28201 cagcaagtta cgtgagctgt ctgctgtttt tggttcgcct ggacgcaaac gttcgtaaac
    28261 gtctttcaaa ccttcttctg ttcttgagtc gcttgcgttt ttatgcaagt ctttttcgac
    28321 tgtattgcgt aatgtttcgc tgtcgccgaa gatttcaaag atcgtatcat cggaaccaaa
    28381 tcctaacgca cgaactaata cggttaaagg aatcttacgt gtacggtcga tacgtacata
    28441 agagatgtct tttgcatcag tttccatttc tagccaagct ccacggttag ggataacagt
    28501 agaaccgaat ccttcttttc cgtttttgtc gacttttcca tggaaataga cacctggtga
    28561 acggactaac tgagaaacga ttactcgctc tgccccgttg atgatgaatg ttccttgttc
    28621 tgtcattaat gggaaatcac cgaagaatac ttcttgtgct ttgatttcgc cagtctcgcg
    28681 gtttgtcaaa cgcaatgtta catgtaatgg tgcagagtag tttgcatcat gcgcacgagc
    28741 ttctgctact gtatactttg gttctttcaa ttcataatct acaaattcca aagatagatt
    28801 gccattgaag tcatcgattg gcaaaatgtc ttcaaacatt tctctaagtc cctcatctaa
    28861 gaaccattgg taagagtctg tttgaatttc gatcaaattt ggtaattcca acacttcact
    28921 gattcttgcg aaacttctac gttcgcgatg ttttccgtat tttactacgt gtccagccaa
    28981 gctcttcacc cctctaaaat gtcattcaaa aagactaccc gatcaattgt tacaataata
    29041 tttcaaatat tatttttagg taacaacaga cattttttgc ggcttttagg caaaaaaaaa
    29101 ccaaaaatag aacattctct tgaaacctta cttcgtgagc ttctactttt gtttccttat
    29161 attaaagccg aaacggacaa tatttcgttt ctgccttttc ttcatcagat agtttttgca
    29221 acttcatata ctacacttat tttctataaa agtcaacact tcctggcgtt tcttctgctt
    29281 tttcgcaaca ttttcttaat gttttcaatt ttatgttttc aattatctga caattcttaa
    29341 ttgacagacc tttttatctc ggttatactt tagaaaattc attttgtgga ggaacttcta
    29401 tgcgaaccaa catcaaccaa atcgcaccaa cacaactgaa taacttttac tttagctact
    29461 ttagataggt ttgtattcat catgatggat acaaacgtta aacgacagtt tgtatctatg
    29521 atggctaaag aactttgtat tgcagcaaaa agccacgtag acaaaatgct aagtggctga
    29581 gcagtgaaaa tacaaagtaa aagtatcaag cattctactt tttcaattta ttttccgact
    29641 tttcaatcca tttggacatt ttgtctgaat ggattttttg tttcccaaaa ttaaggagga
    29701 aaaagaaatg aaaaaaaata taatcatcgg attaggcgct gccctgctac tagctttagg
    29761 aggttgcgca caaaaagaca attccgcaga ggcatcagat ggacaaaaaa caattggcgt
    29821 attgcaactt gtacaacata actcgttaga tgctgcctat aaaggattca aagaaggatt
    29881 agcagaagaa gggtataaag aaggcgataa tctaacaatc gattatcaaa atgcccaaaa
    29941 caatcaagac aacctgaaaa gtatgagtga gaaactcgtc aaagaagatc ctgatttgct
    30001 acttggaatc gccactccag cagcacaatc tttattaaat gaaacaacca ctatcccgat
    30061 gactgtcaca gcggtcacag acttggaaca agcccattta gtcacatcca atgaaaaacc
    30121 tggcggcaat gtgactggca cgacagatat ggtgccaatc gaaaaacaaa tcggcttact
    30181 gttaaatatc gtgccagacg ccaaaacaat cggcatcatg tataacaacg gtgaagcaaa
    30241 ctctaagatc caagctgatt tggcagaaaa agaattgaaa aaagcgggcg tcaaagtcaa
    30301 agtactgaca gcaaattcca caaatgatgt ccaacaagtg acgaaaagtc tagctaaaga
    30361 tgtagatgga atctatattc ctactgataa cacgttcgca agtgcggcaa gtgttgtcgg
    30421 tgaagtcgca aaagaaacaa aaacacctgt cgttgctggc gcagttgatc aagtcaaaga
    30481 cggcggtcta gcaacagtag gaatcgacta cgaaagcttg ggcaaacaaa cagggatcat
    30541 ggcagcaaaa atcttagacg gcaagaatcc aagtgaactt cctgtcgaaa cagcgaatga
    30601 tttggaactg tatgtcaata aagacatggc caaagcatta ggcatcaatc cagacagcat
    30661 caaagaagct gaataaaaca caggaggatt ctcatgacaa atttgctctc tcttttctta
    30721 tcatctgcat cgcaaggggt cttatgggcc ctacttgcga ttggtgtata cgtcactttc
    30781 cgtatcttgg acattgccga cttgactgct gaaggaagct ttcctttagg tgcagggatc
    30841 gcggcagtaa gtattacaaa tggctatcat ccattgacag cttgtcttct aggcttttta
    30901 gggggtgcgg cagcagggct tgtttccgga ctgcttcaca caaaattgaa aattcccgcc
    30961 cttcttgcag ggatcatcac catgactggt ttatattctg tcacatcccg tgtgatgggt
    31021 gcgccgaaca tctctttatt gggtcagcca acgatctttc attgggtcga gtcattcggc
    31081 ataacaaaag acaacgctgt actgatcgtc ggtctgcttt ttgctttgat cgttgtatgt
    31141 ttacttgttt tgttcttacg tacagaaaca ggacttgcta ttcgtgcaac tggcgataat
    31201 ctggcaatga gcgaagcaaa cgggatcaac acagataata tgaagatcat cggttatatg
    31261 atttctaatg gatgcattgc tctttctggc tccttacttg cgcaaaacaa cggctttgct
    31321 gatttaaatt ctggtattgg aacgatcgta attggacttg cttctattat catcgcagaa
    31381 gttttgttac gtaaccagcc actatttctc cgtctcttga ctgtcgtttt aggtgcggtc
    31441 atttatcgtt ttattttagc gttagtcttc gaactgaatg ttgaaccaag tgattcgaaa
    31501 cttgcttctg ctttcgtgct agtgatctgt ctttctttcc cgcagatcca gcaaaaattc
    31561 catttacctc aaaaaaagaa aggcggtagt gtcaaatgaa tgacgtctta acattggaaa
    31621 atctccatca tacctttgaa aaaggaacga tcaacgaaaa tcatgtcctg aaaggcatta
    31681 atctttcctt agatcccggc gacttcgtga cgatcatcgg tggaaatggg gctggtaaat
    31741 ctactttgct gaacagcatc gccggtacat tttctgtcga tcagggtcaa attttattga
    31801 atggaaaaaa tatcacgaaa aaatctgttg tcgaacgttc gaaatccatc agtcgcgtat
    31861 tccaagatcc taaactaggg acagccgttc gtttaacggt agaagaaaat cttgctcttg
    31921 ctatgaaacg aggaaaaaaa cgcggcttct tccgtggtgt caaaccacaa gaccgaacat
    31981 ttttcaaaga ccagctggtt cggctaaatt tggggttgga aaatcgttta tcctcagaaa
    32041 tcggtttgct gtctggagga caacgtcaag ctattacgtt attgatggcc acattacagc
    32101 gtccagaact gatcttatta gatgaacaca ctgcagcgct tgaccctgct acttccaaaa
    32161 cggtgatgga attgacagaa aagctgatca ctgagcagaa tctcactgct tttatggtca
    32221 ctcatgacat ggaagacgcg atccgctatg ggagtcgact gatcatgctg catcaaggaa
    32281 ggatcgtcgt agatatccag caagaggaaa aacagcagct cacagtgccc caattattag
    32341 cgttgttcaa acaaaacagc ggcacggcat taaaagacga tcaagtactt ttatcttcat
    32401 aatcagaaag aggatgggac aaaaaatgaa cgcccaccct cttctttttt ctctttcctt
    32461 ctttcgtttt tgctttatgt atcaaccgtt gtttcttcga aaactatttt gttctctcct
    32521 tcttcctgat agaatggatg ggaaaggagc ttgatgccat gacaacgaaa gacaaggtac
    32581 ttcaattatt gaaaaagaca ccagattttc tttccggaga aaagttggca cagcaactgg
    32641 aagtttcccg gacaagtatt tggaaagcca tcaaagaatt ggaaaaggca ggctatcgtt
    32701 ttgagcacgg gcctacaggg tatcgttacc tgccctctga cgtactagat gcaaaagaaa
    32761 tccagcaaga gctacggtcg tttattcctg atttgaaagt acaaacgatg ttgacttctg
    32821 aatctacgat gaaagatgcc aaactggcag cagctcaagg agattctgtt tcgaagttat
    32881 ttgttgctga tacacaagaa caagctcgtg gacgttttgg acggcctttt ttcgctgaac
    32941 ctggacgagg aatctacatg agtctcttgc tccatccaga caaacggttt gatgaattgc
    33001 ctcaatatac gatcatcgca gccagtgcct gtgtgaaagc cattgaatct gtaaccggtc
    33061 gttctgcttc gatcaaatgg gtcaatgata tctacatgga tggaaaaaaa gtctgtggga
    33121 ttttatctga agcagtcagt gatatggaaa gcggcaggat cagtcatatc atcattggga
    33181 tcgggcttaa tttttctgtt cctcaaaatc attttccagc tgatctccaa gaaaaagcca
    33241 tctctgtctt tcccgacgga caagctagtg tcacaaggaa tcagctaatc agcaaaatct
    33301 ggcaagaatt gttcacttat ctttctcacc cagaaaaagc gttggacttc tataaagaaa
    33361 aatcattcgt attgggaaaa accgtgtcgt tcaatcaaaa aggaacgact tatgtcggtc
    33421 ttgcaaaaga aatcggtgat catggcgaac tgatcgtcca aacaaatgaa cagaagatga
    33481 gtttgtcttc tggcgaaatc agtctcacat ctatccgtac gcaataatta tcagatttca
    33541 caaaaggaca cctgatctca tacagtgtcc ttttttctga attctcttca aaagactctc
    33601 cttattctat cagctgacag tttctctatc ctctagaaaa aggtattcta aaaatatcta
    33661 taaagcatgg tacactttct ttaaatgaat caatgcaaaa aacaagagag tcatcagttt
    33721 acacgatcaa aagagatagc aggccgcttc ctttttcaat cttatagata gaccatgggt
    33781 aacgataaaa acaaaaaaga acttgcgact tattttgccg taagttcttt tttagctagt
    33841 gccttaatct cttaatccca acaaacgtct cgcatagatc acctgaccag agtgcatagc
    33901 agcatcatca ataatagaaa cgagacgcat tcctcgtgtg actggtggtg tccagttctc
    33961 gtcaattact tcatctagct cggaaggttc cagccttctt aagtaagaaa tagcaaaatc
    34021 agcagctcct cgcaagtatc ctagcagatc ttctatttga ttagcttgga tctgctttgc
    34081 ttgttccaga ctatgcttcc aatcttgttc gttatctgct atcgtcatcg gaaaccggct
    34141 ttcccagtct tgactatgcc aaattggaga agttcctgct aaatcagcaa tctggaaatc
    34201 taattctcga gcggtatgcc aagccagcca agtcattgat ttgatctgcg gggctctatc
    34261 ttccactgga aaacgattgg cctcctcaat agagacgcct tcaaacaaac gttcaaaccg
    34321 atcgtatgcc cgatccacac tctcgcatag catatctaaa taatccattt attttcctcc
    34381 tttttattta tcctacttac tttttcctaa ttctaggata cctacttata tgttactaca
    34441 cacccttatt ttttacactt taacagtcac catcatcaat agtttggaga ttgaaagaaa
    34501 aagatagtgt cgaactatca attgaacaag aagcaacaat atgaacgttt cattaatatt
    34561 ctttaaataa acaatgattt ttcaaacgaa cagtttaaga ctaggagaaa aagagtataa
    34621 taggaaaatg tttgaaagga aaggaagggg aaaaatgaaa aaaagggcaa gtttactagt
    34681 cctagttgct ttgttgttca atatcttttc gtatggtgtg gccgtttcag cggaaacata
    34741 cattcctaaa gaccctggga atatttataa tgatctaact ggtaactatg gcttgttagg
    34801 aattgctagt caattccacg tatttgctaa aaataagaca actgtgaatg cacatacaga
    34861 cggaaatata gcaacacatg aacttgatgc aaaaaataat tttggtacag agcttcatga
    34921 aggtttattg aaccaagaaa taaattatat acaaaaaact gattctttcg ctaattcttc
    34981 aggcatacct acaggtagca caagaatgaa taaatttgtc gttggcagta acgtggatgt
    35041 agcacttcaa gatggtcatc ctacagtcaa tggatccagg cttgatcact taactccaga
    35101 tgatttttat aaagatcgtg ctgggcatga atatattgat ttcgagcagg aatttgctaa
    35161 attgaatgta gcagcaaatg atcttgcaac gatcactcca gctaaaacat atactgctgc
    35221 agattttcca gacatgaaca atcggacaat cgatttaact gatttatcag ataccgggtt
    35281 tttattggta aatatcgatg cagaagtgtt aacgatgaat acgccacttc aaatcattaa
    35341 tccaaatgat caagtagttg tatttaatgt catcaacagt tcttctgcat tgaacgtaca
    35401 gtcaccaatc aaatacaatg atcgttcaaa tcatgaaaca gaagattttt cggatgcgaa
    35461 tatctcttgg aattttggaa atgagatgac tgatttgaca atcagtgctc cttttcaagg
    35521 aacaatcctt gcgcctaatg ctactatccg cattactcaa aaccaagacg gaacgattat
    35581 aggaacaaat gtgattttag atgcagctac caatcgttgg gatcctaacg aaatatttat
    35641 cagcgacaat ggtacagata cgacagacac aagcgacagt acagatacat ctaccacaag
    35701 tgatagctca gattcatca
//
LOCUS       DAFBSV010000019        35020 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.019, whole genome shotgun sequence.
ACCESSION   DAFBSV010000019 DAFBSV010000000
VERSION     DAFBSV010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35020
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.019"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(56..2653)
                     /gene="adhE"
                     /locus_tag="LLB18_000908"
                     /gene_synonym="adhC"
     CDS             complement(56..2653)
                     /gene="adhE"
                     /locus_tag="LLB18_000908"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBK5243924.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(2958..3338)
                     /gene="yajC"
                     /locus_tag="LLB18_000909"
     CDS             complement(2958..3338)
                     /gene="yajC"
                     /locus_tag="LLB18_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBK5243925.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(3435..4580)
                     /gene="tgt"
                     /locus_tag="LLB18_000910"
     CDS             complement(3435..4580)
                     /gene="tgt"
                     /locus_tag="LLB18_000910"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBK5243926.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            4798..5496
                     /locus_tag="LLB18_000911"
     CDS             4798..5496
                     /locus_tag="LLB18_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBK5243927.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(5664..8303)
                     /locus_tag="LLB18_000912"
     CDS             complement(5664..8303)
                     /locus_tag="LLB18_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBK5243928.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(8922..9953)
                     /gene="queA"
                     /locus_tag="LLB18_000913"
     CDS             complement(8922..9953)
                     /gene="queA"
                     /locus_tag="LLB18_000913"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBK5243929.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            10146..11321
                     /locus_tag="LLB18_000914"
     CDS             10146..11321
                     /locus_tag="LLB18_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HBK5243930.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            11325..11966
                     /locus_tag="LLB18_000915"
     CDS             11325..11966
                     /locus_tag="LLB18_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5243931.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            11963..12880
                     /locus_tag="LLB18_000916"
     CDS             11963..12880
                     /locus_tag="LLB18_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK5243932.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            12877..13548
                     /locus_tag="LLB18_000917"
     CDS             12877..13548
                     /locus_tag="LLB18_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5243933.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(14089..14577)
                     /locus_tag="LLB18_000918"
     CDS             complement(14089..14577)
                     /locus_tag="LLB18_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HBK5243934.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(14778..15044)
                     /locus_tag="LLB18_000919"
     CDS             complement(14778..15044)
                     /locus_tag="LLB18_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBK5243935.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(15044..15307)
                     /locus_tag="LLB18_000920"
     CDS             complement(15044..15307)
                     /locus_tag="LLB18_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBK5243936.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            15783..15968
                     /locus_tag="LLB18_000921"
     CDS             15783..15968
                     /locus_tag="LLB18_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBK5243937.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(16110..17933)
                     /locus_tag="LLB18_000922"
     CDS             complement(16110..17933)
                     /locus_tag="LLB18_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HBK5243938.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(18531..21236)
                     /locus_tag="LLB18_000923"
     CDS             complement(18531..21236)
                     /locus_tag="LLB18_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBK5243939.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(21542..22489)
                     /locus_tag="LLB18_000924"
     CDS             complement(21542..22489)
                     /locus_tag="LLB18_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HBK5243940.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            22679..22948
                     /gene="rpsN"
                     /locus_tag="LLB18_000925"
     CDS             22679..22948
                     /gene="rpsN"
                     /locus_tag="LLB18_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBK5243941.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(23124..23486)
                     /locus_tag="LLB18_000926"
     CDS             complement(23124..23486)
                     /locus_tag="LLB18_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBK5243942.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(23497..24618)
                     /locus_tag="LLB18_000927"
     CDS             complement(23497..24618)
                     /locus_tag="LLB18_000927"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBK5243943.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(24634..24984)
                     /locus_tag="LLB18_000928"
     CDS             complement(24634..24984)
                     /locus_tag="LLB18_000928"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBK5243944.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(25114..26625)
                     /locus_tag="LLB18_000929"
     CDS             complement(25114..26625)
                     /locus_tag="LLB18_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBK5243945.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(26947..28299)
                     /locus_tag="LLB18_000930"
     CDS             complement(26947..28299)
                     /locus_tag="LLB18_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBK5243946.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(28452..29528)
                     /locus_tag="LLB18_000931"
     CDS             complement(28452..29528)
                     /locus_tag="LLB18_000931"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBK5243947.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            29724..31469
                     /locus_tag="LLB18_000932"
     CDS             29724..31469
                     /locus_tag="LLB18_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBK5243948.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(31749..32186)
                     /locus_tag="LLB18_000933"
     CDS             complement(31749..32186)
                     /locus_tag="LLB18_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HBK5243949.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(32170..33543)
                     /locus_tag="LLB18_000934"
     CDS             complement(32170..33543)
                     /locus_tag="LLB18_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243950.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(33865..34353)
                     /locus_tag="LLB18_000935"
     CDS             complement(33865..34353)
                     /locus_tag="LLB18_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5243951.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(34375..34977)
                     /locus_tag="LLB18_000936"
     CDS             complement(34375..34977)
                     /locus_tag="LLB18_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBK5243952.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         9919 a         7476 c         6466 g        11159 t
ORIGIN      
        1 ttttccaagt tctttttcat ctattttctt atcttttttc tacgctttct tttgcttatc
       61 cgttgtaagc atcaatgatg atctgtttca attcagagat caatggttct ttcggattag
      121 ctgtcgtaca ttggtcttcg taagctaatt cagccatacg gtctacggtt gtatctagtg
      181 tttcttgtgt gactccttga gcttttagac tcatgttgat gccgacagat tttcctaatt
      241 cataaacagc cgttgctaaa gcttcgacta attcctctgt tgtttcgcct ttcagaccta
      301 agaattttgc gatatctgcg taatctgtat ctgcacggaa atagtcatat ttagggaaca
      361 tcgcatgttt ttgtggatct tttgcattat agcggataat atgcggtaaa agaatcgcat
      421 ttgtccgtcc atgagggatc ccgtattccc cgccgatttt atgtgcgact gagtgacaaa
      481 tacctaggaa tgcgttagca aacgccatac cagccattgt agaagcgttg tgcatttttt
      541 cacgtgattc catatcaggt gtttttactg atttttctaa atagtcaaag actaacttga
      601 ttgcttgtag gctcaatcca cgtgtataat ctgaagccat gactgaaaca taggattcga
      661 ttgcatgtgt taacacatcc atcccggtat ctgctgtgac agatgctgga actgacatga
      721 cgaattgagg atcgacgatt gcgacatctg gcgtcaatgc ataatctgct aacggatatt
      781 tcacatgtgt ttcactgtca gtgatgaccg caaatggcgt tacttcagaa ccagtccctg
      841 atgttgtcgg gatacatacg aattgtgttt tttctggttt gtcgatctta tatgtccgtt
      901 tacggatatc caagaatttt tgttttgcac caaagaaaga tgtgtctggg tgttcataga
      961 acatccacat tcccttagct gcgtccattg cagaaccgcc tccaagagcg attactgtat
     1021 ctggcttgaa gtctgccatc agtttcgttc ctgcgtatac ggtatttgtc gatgggttcg
     1081 gttcaacatc tgagaagact tcgatcttca catcattttt acgtcgtgcc aatacttcac
     1141 gaactgtatc gcagtaaccg aattggacca taccagggtc acaaacgatc atgacacgtt
     1201 caacgttttc cattttctct aagtacaata gagagttctt ttcaaagaag atttttggcg
     1261 gtaatttgaa ccattgcatg ttatttctcc gtttcgctac agttttgaca ttgattaagt
     1321 ttacagcaga gacgttacga gaaacagagt tcttaccata agaaccgcat cccaaagtca
     1381 atgacggaat catttcgtta tagatatcac cgatgccgcc ttctgcagat ggtgtattca
     1441 ctaaaatacg acaagctttc attcgaagac cgaatttgac atgcaactct tcgttttctg
     1501 aatggataac tgctgtatgt cctaatcctc caagattcaa cataccttca cacaaatcaa
     1561 acgcatggtc cgtgttgtta gctttgatca tggcaagaac tggagaaagt ttttctcttg
     1621 atagcggata atctgggcct acgccttcca attcagcaat cagcattttc gttccttttg
     1681 gtacactgat tcctgccaat tttgcgattt ccatcgcaga atgtccaacg attgatggat
     1741 tgaccgcata ttttccttcg ttcatcactg catcttctaa tttttgcaat tcatctggtt
     1801 ttacgatata aacttggtgt gcttggaatt ctgcttttac tgctgcatag atttctttat
     1861 ccacgatcac agcttgttca gaagcacaaa tcattccatt atcaaatgtt ttcgaaacga
     1921 tcaaatcgtt cactgcacgt ttaatttttg ctgttttttc aatataagct ggtacgttac
     1981 ctggacctac acctaaagct ggttttcctg tagagtaagc agacttgacc attccagctc
     2041 cacctgtcgc taagacgatc gcgatacctg gatggttcat tagcatagaa gtcgcttcga
     2101 tcgaaggatg ttcgatccat tggatacaat tttcaggagc tccggcagcg atagcagcat
     2161 cacgtaccac tcgtgctgct tctgcagaag atttttgggc acttggatgg aaagcaaaaa
     2221 cgattggatt tcttgttttc aacgcgatca ttgatttgaa aatcgttgtg gaagtcggat
     2281 tcgttgttgg agttactccg caaaccacac cgactggttc agcaatttca atcaaccctt
     2341 tttggacatc ttcattgatc acaccaactg ttttatcatg tttgatatta tgccaaatat
     2401 attcggacgc atacatattt ttgattgctt tatcttcgta aacaccgcgg cctgtttcct
     2461 ctacagccat cttcgctaat ggcatatgtt gatccaaagc tgccattgcc atttcatgca
     2521 cgatatggtc tactttttct tgatcaaagc tttccatttc tttcaatgct gcatttgctt
     2581 tttctgccaa atcatcaatc attgcttgta cgtcaattgt cttcgttttt tctttttcta
     2641 ttactttagc catcattatc ctcctaatgg gtcatggtta tttgttaaat aattcacatg
     2701 tatatcatac aatatttatt tttctatgta aacacttttt tgtgattttt ttcacagtta
     2761 tttttaaata taaaattgct ttatttacag gtgtttgtat agaaaaatat ataaagttat
     2821 ttattattat ttatatgaca cacccgatta ttcaatattg agcaatatat cccatgctct
     2881 tatctctttc ttttttgaat aaaaaatgag gtaggacatc tttctgccct acctcgtctt
     2941 taaataagct ttgatactta tttttcttcc ttctcttctg tctcttccag cgtttctgtt
     3001 gtttcagttt ttacttcaac tgtctcagct ggttcttctg ttgtttcaac agtagtcgtt
     3061 gcatcatttg ttacgacagt ccctggtttg accgttttga ttgctgcacg atcgtactca
     3121 aggaagatcc cttcgcagtc taaaacaact gtccgtttgt cattgtcgat ttctgaaaca
     3181 actccatgta atccgccgat cgttacgact gaatcacctg gtttcatgct atctaacaag
     3241 ttttgacgtt cttgctgttg tttcttttgc gaacgtgaca taaaaaacca cattgctaat
     3301 agcgcgataa acatcacaag cattggtaat gttcccattt ttttcacctc actaattctg
     3361 tatctacaaa aaacacttta gcagaaaaat gctgataaca ctagtttttt acttaatttt
     3421 taaaagattt tcctttagaa gctttttgcg ttttctttat tgaacccgta ttcttcaaaa
     3481 aaggcttctc taaattcaag caaattatca tccatgattg cttgacgtac ttgtttcatt
     3541 agattcaaca agaagtataa attgtggtaa gaagtcaaac gaatcccaaa tgtttcatca
     3601 catttgatca aatggcggat ataggcacgt gtatagtttt tacatgtata acaatcacat
     3661 ttctcatcaa ttggacggaa atcatgggca tatttcgcat ttttcactac tagacggcct
     3721 tgagaagtca tacatgtgcc atttcgagcg attcgagtag gcaagacaca gtcaaacatg
     3781 tctactccac ggataacacc atcgatcaat gaatcagcag caccgacacc catcaagtaa
     3841 cgtggtttgt tttcggggat caacggtgta gtgaattcta atacacgatt catttctgat
     3901 ttaggttccc cgacagataa cccgccgatt gagtaaccag ggaaatccat cccgactaga
     3961 tctttcgcgc tttgacgacg aagatcttca aaccctgctc cttggatgat tccaaataat
     4021 ccttgacggt ctggattagc atgagctttc aatcctcgtt ctgcccatcg agacgtacgt
     4081 tctactgatt ttttcacgta gtcgtaactt tcatcgaatg gtggacattc gtcaaaactc
     4141 atcatgatat cagagcccaa tttattttgg atgttgattg ctttttctgg tgataaaaac
     4201 atacgcgaac cgttcaagtg atttttgaaa tgcacgcctt cttcttcgat attccgcata
     4261 tcacttaatg aaaaaacttg aaagccgcct gaatctgtta aaatcggttg atcccagttc
     4321 ataaatttat gcagtccgcc agcttcttct actaagtctt caccagggcg tagccataaa
     4381 tgatatgtat tacttaaaat aacgccagca cccatttctt tcaactcttc tggggacatt
     4441 gtttttactg tagctaatgt tcctactggc atgaacattg gtgtggggaa agttccgtgt
     4501 ggcgtgatca attcccctaa acgcgcgcca gtatgttttt ctttcttgat taaacgatag
     4561 cgaatggcag gttgcgtcat tcatttccct actttctata taaaatatct tgacaactcc
     4621 caccatcata atcgtttcaa gtgctttttg caagttccct cggcttcctt ctactttatt
     4681 taatattctt ttttttatcc tttttttatg aataacaaaa aaaagaaaaa cattatgaca
     4741 gaaatatttt ttgatacatg gtatattggt gttattaaag aaaaggaggg aaaaatcatg
     4801 caatcttctg cagaattaaa acgccaagca aaagagagtc taaaaggacg ttggggacaa
     4861 gctgttttac taaatctaat ccctacattg attggtattg ctactattct tcttattatg
     4921 attcctatta tcttgtttgc caccaccata tatgatggat cagcgagcgt ctcagaagcg
     4981 acaacttcag gaggcggtag ttcaggaggc ggtggcggaa ttatttccag catcattagc
     5041 gctttgttca tgagcggtat ttcttggact tatcttgata ttttacgtgg acaaaaagat
     5101 cagatcgaac cattcaaaga tgcatttcgt ggattcaaag gtttgtttat cggcggagtg
     5161 atcagcttag ctgtgctgat ctcgatcttt acaacattat ggggtttgct attagttatt
     5221 cctggaatca ttaaaagcta ttcttattct caaagctatt ttatttacta cgatatcgtc
     5281 caagaaacag gacaaacacc taaagtactg gatacgatca ctgcaagtcg aaaattgatg
     5341 gatggttata aaggacaact tttctggtta gatctttcat ttatcggctg gcatatctta
     5401 gcattagcaa ctgctggtat tggttatcta tggctcagcc catacatttc tgcaacaaaa
     5461 gcagcatttt atgaacaatt gccaaaagat atttaaaaga gagtgtgact tgtgaccgag
     5521 ggggtggcag gagaacaccg tttatcgaga ggcagtaaaa gaaacattca gcccattagc
     5581 aaaaaggagg tgtgacaaca ttcatgtcac acctcctttt tgtatagttc cagtaaaaag
     5641 aaaatcaact tagaaacagt taatcattcc tcttcttctg cttccggtaa tcgatggaac
     5701 ttgatcagtt cattcaccgc gattggtacg atagataaaa tccctaccaa gaaccagtga
     5761 ttcaaactga tgtgtactag gccgaatagt tcttgcgtaa atggcagcaa agcaacagcc
     5821 gttgtaatag ctaatgccag taacgccatt tctaccaaag ctttattggt cgctaaattg
     5881 actttgaaga tcgattggct gctgcgtaca ttgaacacat gcagaatcga tgaataagct
     5941 aagatcaaga atgcaacagt ttgaccgaca tgctgacttg cgtctaccca tgggctgata
     6001 gtatcgacat aactacctaa ataataacca aacaaggtta cgatggtgaa gacccctgca
     6061 tttatggcaa ttttttgcaa taaacctcga gcaaagatcc cttcattttt cggaatgggt
     6121 ggctgatcca tgatgccgtg ttccgctggc tctcttccta aagcaaatcc tggaagtcca
     6181 tcagcaacta cattgacaaa cagtagttgc acagctgtaa atggtgctcc ccatcctaac
     6241 agcatcgcaa tcaaaacaat aaagatctcc gaaatattac agcttagcaa aaagttgata
     6301 gctttacgaa tattctgata aaccgaacgt ccttgactga cagcgtctac gatcgtcgca
     6361 aagttgtcat ccgtcaaaat catatctgcg gcactttgcg ccacatctgt tcctgtgatc
     6421 cccatggcac acccaacgtt acttgctttc aacgctggtg catcattcac accatcccca
     6481 gtcatcgcta cgactgcacc cgtacgttgc caagatttga cgatccggat cttgtcttct
     6541 ggcgttaccc gagcatagac agagagagct ttgacacgcg catctaattc ttcgtctgat
     6601 aattgatgca gttctgatcc tgaaagtgct tctgacggat cattcaagat acctaattct
     6661 ttcgctatgg cactggcagt caccacatga tctccagtga tcatgactgt tttgatgcca
     6721 gcctttttcg ctcgcttgat tgctccttta ctttctggac gtggtggatc gatcattccg
     6781 atcagaccaa tcaaacgtaa gtctttttcc agtgcttcag aagaaatatc ttgcggttct
     6841 tcgtcataag tagcataacc aacagcaatc actctcagtg cccgtttacc aaagcgatca
     6901 ttaacgatcg ccgcttgttc tacatcgcct gaactaaagc gcggagcaag aacatcgaat
     6961 gctcctttgg tgattgagat gtatttttcg cccatttggt gaactgttgt catcattttt
     7021 cgttcagaat caaaaggaag ctcgtttact cgtggatatt tttcttctaa ttctgccttt
     7081 gtatgataat tctcttcaac agcccttacg atggctactt ctgttggatt acctttgata
     7141 acaaggtcgt catcttcttg ctcgaccgtc acatctgtac atagtgcagc cattttcaat
     7201 atttccatcg cgctgttcgt cattgaatct tcgatattcg ttacttcatc ttctttgctc
     7261 catacccggc ggacgcgcat ttcattttgt gtcagcgttc ctgttttgtc tgagcagata
     7321 acattagcgg ttcctagcgt ttcaactgct ggcaactgtc ggatgatcgc atgtttcctc
     7381 gccatcttct gcacaccgta tgcaagtgtc aacgtaacaa taacagtcaa ggtttccggt
     7441 acagctgcaa cagccaagga aatcgaagtc atgaacatct caaggagtgg ttctccttgc
     7501 agttcaccaa tcacaaatac taaagccgca gccgctaaag cgatcatact gattcgtttg
     7561 cctagctgat tcaatcggac ctgtaaaggt gttttttgca tagtattttc gttcaaaaga
     7621 tccgcgatct tacccatttc tgtagccatg ccaatggcag tgacgatcgc tttcccacga
     7681 cctgcagcaa ccgtacatcc tttaaatacc atattaagtt ggtcacctaa tgactcatct
     7741 tcttcagcaa taaatgctgc atctttttca actgcttcac tttctccagt caacgccgat
     7801 tcttctacac gtaattgtga tgcttcgatc aaacgggcat cggcagaaat agcatcaccg
     7861 gactctaaaa caagaatatc acccactacc agttgctctg actcaacagt ggtcactttg
     7921 ccgtctcgta tgacagttgc cgtttgttta ttcatatctt gcaaggattc cagtgctttt
     7981 tctgcgtttc cttcttggac aatcgccaat accgagttga tcacaacgat agcgatgatc
     8041 agcagtcctt caaataaatc cccatgttct gtagcaaatg cggtataaaa ggaaatcacc
     8101 gctgctacaa gaaggatgat cgttgtaaaa tcggacaagc ttcgaaagaa ttttttgatc
     8161 atcgattctt tcggcgcctc atcgaattta ttcaatccct gcttttttcg ccgttcatcc
     8221 acttcttgtg aagacaaccc agtatctgga tctgcttctg ttaccttctt tacttcttct
     8281 attgtctgct tgtattcttc catcctattc ctcctttaaa atcttcgtac aaaaaaaggt
     8341 acttatttta ctataacatc ctttttttat ttacttcaaa taaagggctt atcgattatt
     8401 tgttaagaaa gcgtaaaatt taaagtgctt atatttgcaa acgctaccaa aggatgctat
     8461 tatatagatg taaggaagga ggataccatc aaatagacag aagaatttct cgatagaaca
     8521 gtgtaagcaa acaaagttgt tagaagtaca ggtttcaccc agacatgcgt gtagagtaca
     8581 aacctataaa tagtgaatgc gtatggatgt ttggatcacg aagtatccga aacaagaagt
     8641 aatgcgatac gtaacaattg aataacgtaa acgtctgaaa attgaatagg aacaagagat
     8701 gtttcaaatg ttgaagatgt aacgaaaaca aaatttttgt ttaacatgaa gaaattcaac
     8761 accgtgcttt gcatgtatga tggaaagtta caatcatttc tgtttatttg aatccttccg
     8821 aggtacaaga aagccgagct tatcgagagc tcggcttttt ctttgtcata aaatctttgt
     8881 aaagcttttt tgttattcaa aactagcggc ttttcataac cttatttcac gaacatcgca
     8941 tctccaaaac taaagaaacg atagcgctct tcaatcgcat gctggtaagc agataaagtc
     9001 aattctcttc ctgcaaaggc actaactaac atgactaaag tcgattttgg caaatggaaa
     9061 ttagttgaga aagcttctac cactttgaat tcatagccag gcgtaatgaa aatatcagtc
     9121 catccgctgt ctgctttgat ttctccatta aatttcgttc caatcgtttc taatgttcga
     9181 attgaagttg ttccgacagc cacgattttc ccgccatttt tacgtacttg gttcaatcgc
     9241 tcagccgctt cttccgtcaa acggtagaat tcactatgca tatggtgttc ttcaatttta
     9301 tctacgctga caggtcggaa tgtacctaac cctacatgta gtgtcagata gactaattca
     9361 acaccctttg cttcgatctc atcaagtaat tctttcgtaa aatgcaatcc agctgttggc
     9421 gctgcagcag aaccattttc tttcgcatag acagtttgat agcgatctgg gtcttccaga
     9481 cgttctttga tatatggagg caatggcatt tctcccaatg attcaagaat ctctagaaaa
     9541 attccttcat actcaaagtc aatgatccgt ccgccgtgtt ccaattcttc tttcactact
     9601 gcttgcaatc tgccatcacc aaaagagatt cttgtcccaa ctttggcacg tttcgcaggt
     9661 ttgatcaatg tctcccacgt atctccttgt gtattcgtta gaagaaggac ttctaaatgc
     9721 gcaccagtat ctggtttttc tccatataaa cgagcaggca gaactcgtgt attattcata
     9781 actagcgcat caccaggctg taactcttca atgatttcat ggaaatgttt atcttccatc
     9841 tctccagttt tccgatccaa aacaagtaaa cgagaatgat cgcggtcttt taatggtgtt
     9901 tgtgcgatta attcttccgg caagtcaaaa tcaaaatctt ctgttgttaa catatcgtca
     9961 ctcactttct atcatgtgct tcatcattct atcatgtttt tcgttctgtt ggcaaaatca
    10021 gcactttttc acttctattt tttgttttcc taaataaaaa aactacccta tttgtatttt
    10081 ttcattgttt taggcatact agtaatagat agttcttcat tgaaaataga aaaagaggtg
    10141 gcaccatgat tgaatttcaa aatgtgtcaa aaatttataa aggtggaaaa gtcgctgtag
    10201 aggacgtcaa tctttcattt gaaaagggtg agttcatttg ttttatcggt acgagcggaa
    10261 gcggaaaaac gacgacgatg cggatgatca accgaatgac tgatccaaca caagggaaaa
    10321 ttttgattga tggaaaatcc atccaagaaa ttgatccagt ggaattgcga cgtcagatcg
    10381 gctatgttat ccaaagtatt ggattgatgc ctcacatgac gatccgtgaa aatatcactc
    10441 ttgtccaaaa attgttgaaa gtcagtcaag aagaacggaa taaaacagct gaaaaaatga
    10501 ttgatcttgt ggaattgccc cgtgagatgt tagatcgcta cccacatgaa ttatctggtg
    10561 gtcagcagca gcgtattgga gtcgttcgtg cccttgcagc gaatcaagat atcatcttga
    10621 tggacgagcc attcggtgcg cttgatccaa tcactcgtga ttccttgcaa gaccttgtca
    10681 aagatttaca agagcgtttg ggaaaaacga tcgtatttgt aacccatgac atggatgaag
    10741 cgattaaact agcaagccgt atcgccatca tgagtgaagg ccgtgtgatc caatttgata
    10801 caccagaaaa tattttacgt catcctgcaa acgatttcgt agaagagttg attggagaag
    10861 atcgcctact acaagccaag ccaaatgcga caagagtcgg cgaagttatg ctaaatacag
    10921 caatcacgat tacaccggaa aaatcattac aagaagcaat caaactgatg agggaaaaac
    10981 gtgtagatac gttgttagtt accgataatt cgaatgtatt aaaaggattt atcgatgtag
    11041 aaacgttgaa taaaaaacga ggaaaagtat ccagtgtcgg cgacattttg aataaacatg
    11101 ttttttacgt aaaagaatcc gcctatcttc gtgatacctt gcaacgcatt ttaaaacgcg
    11161 ggctgaaata cgtgccggtc gttgatgaac agaacaaagt cgtaggtatc ctgactcgtg
    11221 catcattagt ggatatcgtc tacgatgtga tttggggaga agatcccgca actactgatg
    11281 ttgcagagtc agctactcct gaagaatcta aggaggtctg acctatgcag cagttttttc
    11341 atcagcacgg ttcagaaatt ctctcaaaag gttttgaaca tctttatatt tcaggacttg
    11401 ctttgatcat tggtatcatc attgctgtac cgcttggtgt cttactgaca cgttttccaa
    11461 aagctgccac gattgtgatt ggcttaacca gtgccttgca gacaatccct tctcttgctt
    11521 tattggcatt gatgatcccg ctatttggcg taggtaaatt acctgcgatt atcgcactct
    11581 ttatttattc attattgccg attttacgta atacgtacat tgggatgaaa aatgtcgatt
    11641 ggaattatcg ggatgtggca aaaggcatgg ggatgactga gttccaatcc attttttccg
    11701 ttgaattgcc cattgctatg ccaacgatca tggctggtat tcgtttagct gccgtttacg
    11761 tgattgcatg ggctacactt gcctcttata tcggcgctgg tggtttaggc gatttgattt
    11821 ttagtggact gaataattac caaccagatc tcattttggc aggtacgatc cctgtaacaa
    11881 ttttagcact attggctgat tggcttctag gtctcttgga acaccggctg acaccgatcg
    11941 cacttagaga ggagaatgaa gaatgaaacg tatactaaaa atgaccatgg ttcttttctc
    12001 tcttcttata cttgcgagtt gttccttccc tggtcttgcc agcaatacag atgaagacac
    12061 catttcgatc acaggtggaa tcacttcaga agcacagatc ttagcaagtc tagttgccgg
    12121 aatggttgaa cattatacag ataaaaatac cgcaatcatc aacaatctgg ctactacaac
    12181 tatcaaccat caagcgatga tgaacggaga tgcttcaatt tcagcggctc gctacacagg
    12241 aacagattta acgactacat tgaaccttcc tcctgaaaaa gatccgaaaa aagcgtttgc
    12301 taccgtgaaa gatgaatttg agaaaagata cggtcaaacg tggttcccgt cctatggttt
    12361 tgaaaatacg tatgtctttc ttgttcgaaa agacaccgca caaaaatacc atctatctaa
    12421 agtcagcgat ctgaaaaatg tagcggatga attagtagct ggtgtagata cttcttggat
    12481 caatcgtaaa ggagacggtt atgacggctt ccaagaaact tatggcttct ccttcaattc
    12541 gatattacct atgcagattg gacttgttta tgacgcagtc gaagcaggaa aaatggatat
    12601 tgttcttggc tactctacgg atggacggat cgccagttat gatctagtca tgttggaaga
    12661 tgatcgtcaa ttcttcccac catatgatgc tgctccagtt gtagacaaca agatattagc
    12721 tgatacgcct catttaaaag aagccttaaa taagttaggt cataccatca gtacggaaaa
    12781 aatgcaggaa ttgaactacg aagcagataa taatctagtg gaaccatcag tagtagcaca
    12841 acgtttctta caagaaaacc actattttga agggaagtga agcaattgga taaaatgaat
    12901 gtctttcaac aatttttcta ttatttccag gaaaatggct cctatatctt tgcacaattt
    12961 atccgtcact tcctgatttc tatctatggt gtcctctttg cagcagttgt cgggattccg
    13021 gttgggatca tgatttctag gagacgtaaa ttagcaaact gggtgattcg tttggcgaat
    13081 atcatccaga cgatcccttc tctagccatg atctccattt taatcattgg attaggcctg
    13141 ggagtcaatg tcgtgattgt tactgtattt ttgtattccc tcttaccgat catcaagaat
    13201 acgtataccg ggatgatcca agtagacaaa aacatccttg atgtcggcaa aggcatgggg
    13261 atgactgcta gacaacgact attcatggta gagttaccac tctctgtttc tgttatcatg
    13321 gcaggcataa gaaacgcgtt agttgttgcc atcgggataa ccgcgatcgg tgcattcgtc
    13381 ggtgctggtg gtcttggaga tatcattatc cgaggaacca atgcaacaga gggcacatcg
    13441 attattttag caggtgcatt gccaactgca ttaatggcga tcatcacgga ctggctttta
    13501 ggtattttgg aaagacggct agatccagcc agccgtacat cacgctgatg ttattgtaaa
    13561 aaacaaaagc ttctgcgacc atttgttggt cgcaaaggct tttttagttc tgtcattttt
    13621 aaggcaataa tccactctga ttcttccctc cttatgggca aagagttgct tttcttagct
    13681 atttatccat tccgtatact ccaacttcat actgccaacg ggttcatatc tgcatccacc
    13741 gactaagttt ttttcttatc cgctaaggca ttttgccaat ccattttccc atcactcgtc
    13801 atggaattca taccacatga tctctaaata ctcgtctgct tgttctttga attgggcatc
    13861 aattcttaca tcctttggcg tggctttcat ttaagccttt tccatcagtc ctcgattgtt
    13921 cgatgccttc agctgcatca tcaaaactgg tgactgccgt atcggtaact tcgatcatct
    13981 tttatacaat cgggaacttg ccatcctcat ccttggctaa aaacatatct agccattcca
    14041 gcttctcgcc atgggaggtt tgcggttcct aaaaccggta cacgattctt atggactgca
    14101 tccgtcgcaa ctagacttgg cgatacgatg atccttcacc agaagagcac ccccgtaaac
    14161 caattgatcg atatattgcc aataagaaaa gacattggcg taaaagatat cgatccctcg
    14221 tgatgcattg ccgttgatac tgctattcat ggccgaaagc gccacgactt taacttcttc
    14281 cgtttgagtg acattcatgt tcggcaatgt cgctttggat acccgctctg ctaaaggaac
    14341 gacactggta ttgtatttcg tatctgtatc ttttccaaaa gaccatgcca acgaatcctc
    14401 tgggaaccaa taagacgact ccggttgatt gtccattgct tttttcaaca tacttttggc
    14461 tgtttctcga taaacgacat ttccaattgt cttcgcctca ctttggcgat aatcgatggt
    14521 cgttgccact gccaacacta acaacgatgc tccaatttta ctgattttcc ttgtcacact
    14581 tcttcctcct tgttttacat aaacccgtca acattccatt cctaaactca aacaatgacc
    14641 cttcaaaggt ggagatatag gaacaaatta aagaaatcat gcaataaatc caagaaggtt
    14701 ggttttagaa caaaaaaaga gtctcctttt tggggagact ctttgttaac tatctaaaaa
    14761 ggttggctct tctcacttca ctcataatgt gtccaggcag aataaatttc tacaacttta
    14821 ttttcctcat caactttgta aaccactcga tgctgtctat tcagcctgcg tgagtatctg
    14881 ccttcatgtg taggtctcag cttttcaaaa gactgcgtgg gcatatatgg atcttccttc
    14941 aatgtctgaa tcacttcttc aaattgtttc tttaaattcg tttgcttgat ttttcttaaa
    15001 tccactttcg cagagttttt gattgcgact gtatagttac tcatcaaaga gcttcccaat
    15061 caatatcatc gatattcgta aagctactgt cgtctttttc gcggtctcgt actttatcta
    15121 aagtacctgt ttgctcaaga aaaagggttt cttgaatcgc tctccagtct tccagcccaa
    15181 tcaatacagc attgtttcca ctacgatcac taataatctc gatttcagta tgattttcat
    15241 ttacctcttt caataactga taaaaatttt tacgagcagt gctaggattc atcgttgtat
    15301 tagccattgt ctctcctcct ttttctgata taattatagc gtacttgatt aagtacgtca
    15361 aaaaaataca ataaagcact taaattcagc aaacttttcc tcttttttac atagagaaaa
    15421 agaccccttt ttagggagga tctttgtcca cgctcacttc ttactccttt acgactagcg
    15481 gtagccaaac gtaaagtaat tggtaacaac gtatcatctt tagcaaaggt cgaatccaaa
    15541 gcctgtgagt ctatgcaaca acaccaatac acgaaggttc ctcgttgcag tgtgacttga
    15601 ttgatatctt gaataacctg aggatacgca cgaaagattt gtaacggtta ttcaaaactg
    15661 attttggccg tcaagtcttc tactgcctca aaaatgattg cctctttcgt ctcctgtcat
    15721 tcatgttcac tatcgatttg atacttgctt agaccgttgg gtttgtgaat caccaattaa
    15781 aaatggcact gagttatggt aacaaaaaat ggtcacttga cgaggctgag attcctactt
    15841 atgaagacac atggcactta agagtcgagg taaaggaaga agctgaaaat ataggaggct
    15901 gtacattatt tggcaaagga ttcggaaatt atgatcaaga catcaaaatc aaaatgtttt
    15961 acagctaaat aggaagaata ataacatttc atacgctgtt cccatcttta atggcttata
    16021 gagggcacct ttagctgaga ataagacaaa acagaccctc tagcttcaat taagagctag
    16081 agggtctgtt tttgatttta aaacttggtt tatttcttca aatggtagct ataggtgctg
    16141 acaacgatat tttcacgcca agacaatcgc aatcttaacc gcaaacttgt ttggttatgg
    16201 agaatattct gccagcgtct gtttggtaca aattgaggaa tcaacacagt agttgtatag
    16261 ttttgtttcg ctgcattttt acttacgata tctacataac ggataattgg attttcaatc
    16321 gagcgataag aagagtggac gattgaaaaa cggacatctg ggaaatgctt tttaaattct
    16381 gcttcgattt ctttttcttt ttcgacatct tcgtctagcg aaacatgcat cgcaacgaca
    16441 taatcaccga tcgaacgtgc gtaattcaac gcaccgatat ttacccgtgt cacattcccg
    16501 actaatacaa gaacggtatt cccgtcataa tcatgtagtt ttgcatcatt ttctaaacga
    16561 agctgttctg ctactttttt ataatgatca tggatcttat aaaaaatgaa cataacgatt
    16621 ggcataatga tgaagaaagg ccaaatgtcc cctaaccgat agacaaacaa aatcgcaatg
    16681 attgcatatg agatgaacgc acccgtaata ttggcaatcg atttgcttaa ccatcttttt
    16741 ccttcttttt tccatttgac gaccatccct gtttgagata aagcaaatgg aatgaacacg
    16801 ccgatagagt ataacggaat caagcgttct gttgagccat ggaaaataaa cagcaatacg
    16861 atcgaaccta gcgctagtgt gataatccca ttggaatagc ctagtcgatc cccacgatct
    16921 tgatacatgt gaggcatgaa tttatctttt gccagattgt atgcaagaac tggaaaagca
    16981 gaaaaaccgg tgttagcagc aactgctaaa atcagcgctg tagcaaattg aaggacgtaa
    17041 tacaaaatac catgtccaaa gacagcttta ccaatttgag acaaaacagt gacttctttt
    17101 tcaggaacga tcccatacca atagttgata aatgtgatcc ccacgaagaa gaaacctaag
    17161 atcaatgcca tcatcgtcaa tgtagcagcg gcattttttg ctcttggctt cttaaagaat
    17221 ggtacagcat tactaatcgc ctccacccca gttaaagagg aagaaccaga agaaaatgct
    17281 cgtaaaatca aagcgataga aacacccggc acagccgctc ctggaagtgc agtagcttgc
    17341 aatggcacag cacctgtcac gatattatat aaaccaacaa cgatcagtaa cgagatcaca
    17401 aggataaatg tgtacaccgg aaataatagg aacgatgcag attccctcag cccacgaaga
    17461 ttcagcatca tcagtagcaa aacgattgtc acagaaatag cgacttgatg accgtagagt
    17521 gctggcaccg ctgatgtgat cgcttcagca cctgctgaga cagatactgc tactgtcaac
    17581 atgtagtcga tcaataaaga gccaccggaa atcaagccag cattctttcc aagattctca
    17641 ctgctgacga catatgctcc cccgccatga ggataagcat ggatgatttg acgatatgat
    17701 agcgttaatg aaatcaataa aataataaca aaagcggcaa tgggtagcga ataccagatg
    17761 gctgcagcag acaaagcgac taaaacgaca acgatttgtt ccgtaccata tgcaatagat
    17821 gataacgcat cagacgacaa taatgccaaa gcagcaaatc gggttaattt gtgctcatca
    17881 ttttcagcag attttaaagg cttacctact aacaaccttt ttaagtaatc caatttctaa
    17941 actcctttac acacaatttt acttcaagtt ttatagtcga aaatttatag taaacaagat
    18001 gttatagtac gctcactgac cttaaaagtc aataaacttt aagaaaataa ttggaaaaaa
    18061 acagaaaaat atcaagcgct ttttcaaacg ctttaataca gcaaaaatct aacatttttt
    18121 tatgggcttt ttctttgaat tctataataa aaggatagaa cttgacttag aaaatcaagt
    18181 tctatccttt ttgatatctt aacttttgga agagagatgt aaggctgctt tctacccatc
    18241 attcttacta ctcgaagcat agcgcagttg tcacaacctc ttgataaacg gtgtttaaaa
    18301 gcttgcatct gcggtaataa gctcaaccaa attaaaaaca taagaagctg tttttatttg
    18361 gtcgttctta ttacttgatg cagagcagct tttttacaac ctcttggtac acggtgttca
    18421 atcagctgac cctcggtatt agctcaaaaa aacggcaaaa tatgaggaac tatttttcca
    18481 tttttttctc taatactcag gtcaaaacac tgatttcaca acctcttttt ttaatgaaaa
    18541 atatggctct catgcgccgc ttctttgaat ttcgtcattt tttcttcgat gaacggatag
    18601 attgccgttc ctacgattcc aaagacaaca aacaaaccga tcatgatcca gattgctttc
    18661 gtagcatttg gccaataaat tcctcctgca gattcccgta acaagtttac cgcatgagta
    18721 aatggcaaga acggattgat catttggaag aatttccctg agacttggat cggatagttc
    18781 ccgcctccgc cagagatcga cagtactaag atgataatag cgatcccttt accgacatta
    18841 tcgaataatg cagccaagac atagacgatc atcatgaacg ctaaggcgat caagacagca
    18901 aatgacacgc tgtagaccgg attttggaca tctactccta gtaagaaaat attccctaat
    18961 gtaacgatca agctttgcgc aatcgccatt gtcaaaaatg tcagcatacg agcaacgaat
    19021 tgttctcgtt tcgtaaaatt gtttcggtct ttctttccta aatagtattc tgtcgtagca
    19081 acacttgaaa gaagaacagc gccgacccac agacatagtg cagtataaaa cggggtgcta
    19141 gctgaaccgt tatttgcgat tggataaagc gcattggttt gtagctcaac aggttgtgta
    19201 aagaagtcac tttcttttgt tgcgtctagt ttcaataatt tgatgacttc gcctagatcg
    19261 acttcttgtt cgccttttcg gatcgcgtct gctgcttttt ggataccagc tttgatattt
    19321 ggccagtcat tgttgatcaa gtccgcagca gcgttcacag ctgtttcgac ttctggcatt
    19381 ttttcattta ctgttgtcaa tgtaccggtg atttcatttt ttagtgctgg ccaatcattt
    19441 tggataaaat cagcggccaa tcctaatttt tgctgaatga tcggtaattc attgttgtat
    19501 aggtctgccc cttcattgat gccattgacg atggtatcca tatttccatt cagcattgta
    19561 ttggcatcat ggatttcttg tccaattgca ggcatttctt tttgatattt ttctaaaatt
    19621 gccactgcat tcgttacagt tgctttcgtt gagctgagaa gcgaatcaaa gtcgatctgg
    19681 tccgctttgc tcagtgcgcc ttgtgcagtc ccaatcgtat cgatgacttg gtctagtaga
    19741 gaagtgacag tggaactgat ttgacctgta ttgataccag caatgatgcc attgatatta
    19801 ttaacaacgg catcaatttg atctagcaat tcatcaatag ccttcgtgtc ttcattttga
    19861 acagctgtgt tcaaagcaga taggcggttt tgcagattgc ttagcaaggg ttttaattga
    19921 tttagctgat caataattgg ctgtaatttc gtatttccag cacttgtttg caatttagtc
    19981 aggaactcga ccagtttatc gattgcattt tgttgttgag atattccgtc aataaagccg
    20041 ttcaatacat tgctgatgtt tttcttttca tcatcagtca gcttaccatc ttcaatagct
    20101 gttcttacag tatctattaa cgaacctgtc gttgttgcca cttgtccaat tgacttcaat
    20161 gtaacatcta cactgtttgt gatgcttggt atcgcatctt tcagctgaga ggcacctgat
    20221 tttgtttggt ttgctagatc acttgcctga ttttctaaat ttttcacatc tggcaagata
    20281 tcttgtactt gttggatgat cgtcaagcct tgttttgctt catcgattcc ttggttcatt
    20341 gtctcttgga tcgaagcaaa atcgccgtcg atctctgcta gttgcttacc ggcattttgg
    20401 atctctggga ttttttcttg caaatcaagg atgatttttg cttgatcttt caactcaggc
    20461 attttgtcat tcaatgcaac gactttttca cccatctcat ctactttagg gatgtaatcc
    20521 acgaattcat ttgctttatt cagtttttcc ttgatttcag gtagttgact ttgtaattcg
    20581 aggacttgtt ttgtgtagcc gtcgatcgtg tccaaatttt catctgttga taaaatcata
    20641 tctttaactt tattgatact tactaggttc gtatcgatgt cgtaacctat ctcattgaat
    20701 actttcaata aagtcgaact ggctgttttg ataaattcat ttgtgatttg cgattggatc
    20761 gaacttgctc ctttatcggt gattttcggt gcaatcgcat tgattttttc atttaccgta
    20821 tattcgattt ttggtttctt gatatcacca ctagtaaaac tcagcagatc ttctgagaaa
    20881 tcctttggca agtaaatacc tgcgtaatac tttccggaac ggactccgtc ttctaattgt
    20941 tcttttgaat caacgaattg ccatcctaat tgtttatttt tatgaagcga ttcgatgact
    21001 tgctccccaa tggccacttc tttaccttga aactctgctg gcttgtctgc actgtaaaca
    21061 gcaattggca gctctccagt atttccatat ggatcccata atgctttgat gttaaaccac
    21121 gcatatagcg aagggatgat catgatcgcg atgatcagaa gtgttgcaat cgggtttttg
    21181 aaaatccgtt tccagtcaag caaatataat cgaagcgtat ttttgattga ctgcatagtt
    21241 ctcccccttc ttcttttttc agctgaatta ctttaccatg tatttcatac ttttttcaat
    21301 cggctttttt caaaaaagtc gaatttttgg acatatcacg gcaattgtct cattgtaatc
    21361 tcttacatat tgagaaataa ttaaggatta cagcctttac tttatcatga aataaaaggg
    21421 aaagataatt ttatgccaaa gtttttatct attatacgta tacgcaaaaa agctaaaaca
    21481 ttttttgtct ttgcccctac aaaaatgttt cagctttttt cgttttttat tcctgtattt
    21541 cttatttttc gaatgacagg atgattttcc cagcaggagg atgtccttca actagctgat
    21601 gtgcttggat gacatgctta agtgaagcag acagattcat tgaaataaaa acatgaaagg
    21661 ctcctttttg gtaggctttg attatgccag caaaggcttc tgcatctaga tattcctttc
    21721 ttggaacaaa cgattcataa aagccttcct ttttttgccg caaatctaga tctgggaggt
    21781 catttaatgc aacatacctg ccgcctggtt tcatgatctg gatgccggtt tctcctttga
    21841 tacttccttt cgtcgcatcg attacaaggt ctgcctgatc agcaaattgc agacctggat
    21901 ttgttttatc ataagcagca aatgctgaag ctcctaattt ttttaccttt tcctcatttt
    21961 tactggatgc actggttaag attcggattc ccttttcatg gagaagctgg atcagacttg
    22021 acccgaccgc acctgatgct cctagtatca ttacagtatc tgtcggctgg atttccgtca
    22081 aatggttgat tagattataa gccgtaattc ctggcgtgac cattccggct gcttcttccc
    22141 aactcatttt atctggaatt tttgctactt ttgctgatgg caacacgact tcttctccgt
    22201 aagtcccgcc gactgcatgg acagctactc gatcacctac atgaacagtt gtgacatctg
    22261 aaccaatctc tgtcacaata ccagcgccat cattacctgg tacataaggg aatttcaatg
    22321 ttcgtatctc tttcatttct cctaaacgca aggcaacatc ataaggattc acactgaatg
    22381 cttttatttc tacacgaaca tgtccagaac cgacttctct gggatgagca tcgatttctt
    22441 caaaaacatc ttgtgcttct ccgtaaccgt taattgcaaa tcttcgcatg gtcaccatct
    22501 ccctttttct ttaagtttac gtttatgtct ttattttgac aaaaaaaatg tcttttcgtt
    22561 ttggcgcatg attcaaaaca aaatagttgt cttttttcgc gtaacgtgtt aaattattta
    22621 tctaaaagcg taaagattac gatttacgct aataaaaaat aattggagga atttgttgat
    22681 ggctaaaaaa tcaaagattg ccaaagcaaa aaaacagcaa gaaacgattg aacgctatgc
    22741 tgctttacgc caggaattaa aagcgcaaaa agattacgaa ggcttgcgta aacttccttt
    22801 agatgctcgt ccagaacgat tgaaaaatcg tgatttaatc gatggacgcc ctcgcggata
    22861 catgcgtaaa ttcgggatgt cccgtataaa attccgtgaa ttagcacata aaggtttgat
    22921 tccaggagta aaaaaagcca gctggtaatc caagtctggc tgtaatgtaa aggaggaggg
    22981 cgcatggacc actccttgga tcatcaaaaa agatacgttc gcttcttcta gcagaaatgc
    23041 tggtactaga agcagacgta tcttttttta cgcacagctg gtcctttttt atatgtaaag
    23101 gctgcatggt tacttcgcta tatttattta gtaacaggag tcagtgcttc gatacccaca
    23161 ctaattttca atgctcggtc aacttctgcc ataatgggtc gatccaaatg gcagaccttt
    23221 tctttcaatc ttgatttatc gatcgttctg atctgctcca acaggataac ggagtctctt
    23281 tctattcctg ttccagtagc tttgatccca atgtgagtcg gaagcttagg tttagccatt
    23341 tttgccgtta tggccgcaac aatgatcgtc gggctaaaat ggttacctag attattttga
    23401 ataaccaaaa ctgggcgtgt tccgccttgc tccgatccca cgactggaga aagatcagca
    23461 aaataaatat ctcctctttt taccatagga tcctccttat tcttgatatt ctcttggtat
    23521 ccgctgtcct aatccgcaag ccacttcata gtggatcgta cctaattgat ctgctatatc
    23581 ctgcatagtg atttctttgt ctgcattttt gccgataagc gtcacttttg ttccgacagg
    23641 aaattcttga ggcaatcgga tcatcagttg atccatacat acacgcccaa tcgtttcaca
    23701 gtagttccct tctaccaata gagaaaaacc ctgcatcttt cgtggccagc catctgcata
    23761 accgatcggt atcgttccga tccactctgc ttcaggagtg atatatgttt ctccatagcc
    23821 gattccttca cctgctggga gttttttgac ttgaatcaat tcagaaacca gctcaagtgc
    23881 tggctgcaat ggataaactt ccggtagtgc gtgcccagag ggattaagtc cgtacattgc
    23941 tactccataa cgaatcatat tgccgattgt ttcatcatgc cataaagccg ttgcactatt
    24001 gctgacatgt acatatcgag gaagttcggg aagttttttc agcacttcta taaagcgttc
    24061 tttttgcaga ttccaatatg tatcatctgc ctgatctgct gtagaaaaat gggtaaataa
    24121 accttcccat tctaatacac gactttcttt gatgaatgca gctgcctctt ttacttcttc
    24181 aggtgtacaa aatccgatac gacccatccc agtgtctgct tttagatgaa tcgaaagagg
    24241 cgtctctagc ttacttttct ctaaaacagc agctgctgct tgcaaccatt cccgtgtacc
    24301 tgcagttact gataaatcat gagcaacagc tacagtcagt gcgtcgtaag gaaccatatt
    24361 caagataagg atgggctgag taaatccagc ttctctcaac tcgactcctt catctaaatt
    24421 tgaaacacaa aagcccgaag ctccacctgc aactgctgcc tcagctgttt caatagctcc
    24481 atgaccgtat ccgttcgctt ttactactgc aaacaattct tttccttgcg gaagtcttgc
    24541 aacttcattt gctacatttt cagttatagc ttttttatgt atcactgctt tcgttgggcg
    24601 gtgccaagcg acaaccatcg tttttccttc tttctagtct tccaaaataa tttgtgcaaa
    24661 agctgtttca tttgtatgag taatactgac ccatacattg ccttcatgag gtgaacgcgt
    24721 cacaacaggc tgaccatttt cattttttaa aatctcgaca tcttgaaagg taacttttcc
    24781 gatcccagtt ccccaagctt tagagaaagc ctctttgcaa gcgtaacgcc cgcctaaaaa
    24841 ttctacttgg cgatgaaaag gcaaggactg gaatagtttc atttcatcag aggtcaagat
    24901 tcgtgcaatg aattttggtt tttcttcgat cagccgagtg atcctaggaa gttcgactgc
    24961 atcgatccca attcctttta tcatatgctt ttctcttttc aataaattta gaacactctc
    25021 attctaccaa attataacca ttttgccaca aataagtcca caaataacaa aaatgaaagt
    25081 ttctcttaaa aaagagaaac tttcatttta tgtttaatcg ttatttgaac ggattacaaa
    25141 tccgcgtttt ttatcattgt gacgtttacc gccatctttt tggctgttat tatttttgct
    25201 ataaccgcct tttgatttgt ttccacgata attaccgccg tcacgacgat tacggttgtt
    25261 tccgccacca cgtttgccat ttttattgta tccttttttc tgcattggca atgggcgttc
    25321 tggtgtgatc ttcactggca ctgcatcagc tggatctttt gctgtcgttt ttagcaaaag
    25381 tgcaactaaa tcttgtgcag aatattcttc taataattta tctgctgttt gcaggtattt
    25441 atctagacca ttttctgcaa gttttgtttc gatttgttca actgcagcac ctaattgacc
    25501 tttgaatgct tctttttcgg ttggtggacg taaagtcgtc atccgttttt tcgtcaagtt
    25561 ttcaatcaca tgcaagtagt ccatttcatt tggtgtaacg aaagtcacag acataccgcc
    25621 ttttccggca cggcctgtac gtccgatacg gtgaacgtag ctttctggat cttgagggat
    25681 atcatagttg tacacatgag tgacacctga aatatctaat ccacgtgcag caacgtctgt
    25741 cgctacaagg atatctaaat gaccgctctt aaatgaacgc aatacgctca ttcgtttttg
    25801 ttgagacaaa tcgccatgga ttccttctgc acggtaaccg cgtgcttcta atccgcgtgc
    25861 caattcgtct acacggcgtt ttgtacgtcc gaagacgatt gttaattcag gtgtttgaac
    25921 atcaaacaag cgagtcatga tatcgaattt ttcgtattct tttgcgcgga catagtattg
    25981 atcgatcaag tcagctgtca tttctttcgc tttgatcttc acatgatgtg gatttttcat
    26041 gaatttaacg ccaatattct tgatagctgg cggcatcgtt gctgagaaaa gtaatgtttg
    26101 tctttgatca ggaacttgtg aaatgatttt ttcgatatct tccaagaagc ccatattcaa
    26161 catttcatct gcttcatcca aaactaatgt ttgaacggtt ccaagtttca atgtgtggcg
    26221 gttaatgtgg tcaagcatac gtcctggtgt acccacaacg atatgtggac gatctttcaa
    26281 gccacggatc tgacggccaa tatctgctcc gccgtaaacg gcttgtacac gtactttttt
    26341 gtcgcgccct aaacgatata attcttcttg tgtttggata gctaattcac gtgttggtgc
    26401 gataactaaa ccttgtaatt cgtgacgatc tggatcgatt ttttctaaca ttggtaatcc
    26461 aaatgcagct gttttccctg tacctgtctg tgcttgtcca ataacgtctt ttccagctaa
    26521 tgctagtgga atcgtttctg cttggatagg cgttgcttct tcaaaaccag cgcgttcgac
    26581 tgatttcaac aattctggtg ataattctag ttctttaaat ttcaaatgaa tcctcctata
    26641 tggttgttaa ctgaggatgt agcttttttg ctaccccgtc gatttgttcg gtcaaagtgt
    26701 attgtttctt tttgacagtg gccacgcacg tttttatcca ttcttagccc ctgtggcacc
    26761 accgaaaaat cactttgcga agtttaggca ttagaaaagc caaacgggtc gcgttcagct
    26821 ttatcattat tatgacatct ggcttcaaca agttgtttct atggcaaaac cagtccaatt
    26881 tctcttcatc tttcggcaat aggttattct aacatagttt ttcgttttct gcaagtttac
    26941 agatttttat ttcatttgct gaagttgttc taccacttca aataagccca tgctgttgct
    27001 gccttttagc ataatactat ctgttgctgc aagattttgt ttgatagcat caatcaattt
    27061 attcttttct ttttcaaaat agaacacagg tagttggggg tatttttggt tcaattcttc
    27121 ttttagtgca tgcatttgtt ccccataaag gaaaatcatg gcgaatttct caggatcgat
    27181 atgttcactc atttgcgcat gcatatttaa agactctttc cctaattcca gcatatctgc
    27241 taacacagcg attctgcgtc cttttgttgg cagattttta aaagtatcta ataccagtcc
    27301 catggctgtt ggatttgcat tgtagacatc gctcaaaata gctgcaccat ttcctgccgt
    27361 tagccattcg gttctgtttt gagtgataga aacatgggcg agcccttggc gtatctcagg
    27421 tatggacagt ccaaagaagc gcccgatcgt atacgcaatc aaagcattcg ttacattata
    27481 acttccaggc agcgggatcg taaatgtttc tccttctact acaaaatcgg tttgtgcttt
    27541 tccttttgct gtcacttccg catgaacatc gccatttcca ataccgaatg ttgtgactgt
    27601 ttgtactaat gttgccgtta aaggtgtcag caacggttca tctgcgggca caacgagtaa
    27661 tccgtctgat acaagtccgt cagtgatttc cattttggct ttagcgattc cttctcgcga
    27721 cccaagattt tctatgtgtg cttcaccgat cattgtgatt gctgcagctt ttggttgagc
    27781 cataagtgaa agttccgtga tttcattggc gtgatccatg cccatttcca aaacgatctt
    27841 ttctgtatct tggggcatgt gcaaaatcgt gtaaggaaga ccaatattat tgttgtaatt
    27901 tccttgcgtc ttatatgttt tgtatttttc agacaagaca gacgcggtta gatctttcgt
    27961 ggtggtttta ccattgcttc ctgtaattgc aacgacttct gcgcctactt tttccaagta
    28021 ataggttgcc aattgctgca tggctttcaa aggatctgct acaggaataa ctggaaaatt
    28081 ttttggagct tgttcaacag gcaagctcca aaatgaagca gatgctccgt ttgtgatcgc
    28141 ttgctggata aattcatgtc catctcgcgt accagcaaga ggaacgaata aacttccttc
    28201 ggttatcttc cggctgtcaa attcgacatt ggtaatcttt gtcagtgcag agcattcgct
    28261 gcccacggct tgtgcaattt cttgtattgt tagattcatt gagatctctc ctaaaaaagg
    28321 ttgtgaaaaa agcgtttggc ctaaacggcg ggttcgcatg actctcactt ccaagtaaat
    28381 ttctctattc gtatttagaa gctagaatga acgcggttac gcaatcactc cagcctcttc
    28441 tttatttctc tttattcatt tttttcaaaa aaagattgac gctgatggta tcgattcatt
    28501 cctaactgga tcagttcttc aatcaaatca ccgtatttca agcccatatt ttcccataag
    28561 agtgggtaca tactgaactc cgtaaatcct ggcatagagt ttaattcatt caggaataat
    28621 tcatttttat ttgtcaaaaa gaaatcgcac cggctcaatc cgcttccacc taacatcgtg
    28681 taagctaact tcgcgtactc ttgcgctttt tgataaactt cttctggcac ttcggctgga
    28741 atctgcattt cgattttatt attgatatat tttgcttcat aatcatagaa tgctacgtct
    28801 tttacgactt caccaggcaa agtcgtccga acgtcttcat ttcctaatac agcaacttcg
    28861 atttcgcgcg cttcaattcc ttgttcaacg attgctcgag aatcatactg ataggctgtt
    28921 gctaaagcat tttgcagctc ttctcggttt tctgcttttg taatgccgac actagaaccc
    28981 atattcgccg gtttgacaaa catcggataa agcaaagaac cttcacattg atcaaatact
    29041 tttttaggat tttctttcca ttgattctta agtactggta cataaggaac ttgcggcaca
    29101 ccagcagctt gtaaaatata cttggtcatg attttatcca tggcacatgc actggtcaat
    29161 acgcctgcgc cgacataagg catattcaat gtctctaaga agccttggat cgttccatct
    29221 tccccgtttg gcccatgtaa aactggaaaa acgatggctc cttcttcttt gatttcgccc
    29281 ggattgatca cttttcctgt aaagccttcc tctgtctgtc cacttgggtc ccatgaaaga
    29341 tgcaagacat ctttgctggc aggtttttct gttagtaatg gacctttgac ccattgtcct
    29401 tcttttgtaa taaatacgag ttgaacttgg taataattat aataaatggc atttaaaact
    29461 gaaaatgcgg aaagaatgga cacttcatgc tctgcgctgc gtccgccata tagtaaagta
    29521 atcttcaaaa gattgtcctc ctgtattcta aatcgttcag tgatttactc tcatatttta
    29581 gcacaaaaca aaaataaacg aataacttat ttataaaaaa acgagccagc ttctaaaaga
    29641 acgagcgtca tttatttttt gtcagctaga ttatttgtcc cgttttttat aaaaagttat
    29701 gataaagaaa aggagggatg atgatggcgc aaacaaatcc acgcagccgc ttggcagaaa
    29761 tcattcgagt gttcatcaat tacaatgtag tgccaaactt tgtacagcaa aaaaatcccg
    29821 aacaggtaaa aaaagccttt gaagaactag gccccacctt catcaagata ggacagatgc
    29881 tttctgttcg agaagatttg ctttcttctg ccttcactca aacattcaaa acattacaag
    29941 atagtgtacc tagcgacaca ttttcaacgg tcaaaaagac gatcgaaaca gaactttctc
    30001 tttcattatc agatatattc gatgattttt caaaatcgcc ttttgcctct gcttctatgg
    30061 ggcaggctca tcgtgccaag ctgaagaacg gtgacgcggt agtcgttaag atccaacacc
    30121 ctaacatcgc cgaagagatc cgacttgatc ttcaactatt tgaacgagcg atccctttga
    30181 tcaaatacat tcctgaaact agcgtagttg atctaaaagg ggtactccaa gaagtaaaac
    30241 gttccttgat caatgaaatg gacttcttaa aagaaagtca aaatggcgaa caattctatc
    30301 aaaagaacaa tggctggaaa gagatccgca gccccaagat ttatgacgct ttttgttcga
    30361 aaaaagtgat cgtgatggaa gaaatgtctg gtaaaaactt gaatcattta atgaacgccg
    30421 aaaacaaaac tgaaactttt atcactggaa ttcaaaacaa gcagctgaaa caagaagttg
    30481 caaagctttt agttgagaac tttatgaaac aggtgtttga tgatggtttt ttccatgctg
    30541 atcctcatcc agggaatctg ctattccatg tactaacaaa agaagaacag acacaagcta
    30601 gccgaaaaac tgaaacagtc catgaaaaag agttcggttc ctttgctttt cgagcctcca
    30661 cttctgcaga agaccctgtt gcgccatata ccatcaacta catcgatttt ggtatgatgg
    30721 ggcatctttc tgcaggactt aggcaaaaac tcacacaagc cgttttagcg ctgtatacga
    30781 aagatgctta tcgaatcgaa aaagcggtcc ttcgactttg tcagcaagaa ggctcgtttg
    30841 atgaaagtcg gttccaccaa gaactgacaa gttttcttga acagtattat gattctccta
    30901 ttgatgaaat caacttgcaa gaagtattca cacatgtcgt gacgatttgt catcaaaata
    30961 atctgcagtt cgatcgtgat atcacgcttt tgctgaaagc atttgggaca ttagaagggg
    31021 tgatccgcgt cctcgatcct gaagtttccc tcatggaagt cgcttcgcct tttgctcaac
    31081 attattttct cactcatctg gatgtagaag atacattgaa acaaagcgga ttagacttat
    31141 tggaagggat gaaggctgcg cctaagatcc ctcaacagct ccaccatcta ttagaaatgt
    31201 ggacttcggg acaaggaaaa gtcaatttgg aattgaaaaa gcaagacaaa ttattgagca
    31261 ggatcgaaag tatgatcaat cggcttgttt tcggtatgat tttagctgca ttgatcgtag
    31321 ggtcctccct gcttgtccaa gcagcacctg tagaaaacgc agaggtcgtt tccttattag
    31381 ggatatttac gtatgctatt gccgcattcg tcattatttt tttggcaatc gatgcattga
    31441 tccaaatgta taagaagagg aaaaagtaga aaaaggttgt gacagaaaga atcagcttca
    31501 agaaataaga aggggtttta cataaattgt ttctcaaatt tttgtgaaaa ttcggcttat
    31561 ttttcgaaga ggctacttct gaaacaccga gaataaaaaa tgtgaaaaag ctgttctgca
    31621 cccagtaata agaacaatca aaaagggaac atggaacaca tttatcctgt ttccctgttc
    31681 cctttttgat gtattcgagc ataaataaaa taccttcgtt acctactatc ttctgtactt
    31741 ggtaaacctt agtcaattgc cttttttaac gcttgacgaa aagacatatg atctttctcc
    31801 gtaaagggtt ttggaccctt tgtccttatg ccagcttttc ttaactttcc actatgataa
    31861 cgttgttcta gaagcgtgcc gatattcgct tcgtcaaatt cttttccaga gtgatggaac
    31921 actcgcacac ccttcggcaa tacaagtgaa gctaaaccat aatcttgcgt gatcaaaaag
    31981 tcattcttct taaccatacc gacgatttta taatccgcac tatcagctcc gcggtctacg
    32041 tagacgattt ggacatgatt agcgtattct ttggtcgtat aatggtccac actggtcacg
    32101 ataaccacgt caagaccata ggattctcct aattttatga catcttcttt tactggagaa
    32161 ccatctccat caatgaatag cctcattctt tttcgccttc ttccataaat gataaacagt
    32221 tactaatccg ctcagtaaaa gaccaacatt gatccatttt gccaagataa gcagttgtac
    32281 actttctatc ggcactgatt catggttcag cgtgatcaat aatagatgga ttggctctcc
    32341 catttctttt gctaaaacaa acaaaagcgt catcaataaa aactggtgga tcacactccc
    32401 tttattttga gtagtatact tgacaacgat ccggcgatcc attggaatag ctgtatcagt
    32461 ttgataatat tccttattta gccagctgcc tgttactacg tgccagaaac taagcagaaa
    32521 gacacctatc gcaaaaccat ttggaatcaa gaggaccaat aaagaagaac tcagtccaag
    32581 caattgcata gccaatggag accatgttaa acgtttcaaa atccatggtc cgactatttt
    32641 tgctgcaatc aagcctgctg cataaggcaa atacataaaa atcgaaagtt tttctaatcc
    32701 gtacagtatg ccaacataaa aactgctaaa taaaaaaagg aaattcccta gcattccatt
    32761 tagaaaagta aacagattta gccagcttgg caacttccat tccttcttct ggtgtcctaa
    32821 aacaaacacg aacaagatga acagcagcaa gaaaccataa atagcaagat caaaaagcct
    32881 ttcatcgaat aacaatcggg catttctcaa aagaaacaat aagccaaaga atatcaaaaa
    32941 taaaacaagc tctcgcgtag ctaccagatt tcttttgatg tctttgaaat ccagttcgta
    33001 acgcggataa tgactaaccg tatggtaggc catgacgtaa aaaagtgtat aaatagtaaa
    33061 gcttgctgca atctgagtcg gtgcaggcaa ctcaatcgct tgatacagga gaaatagcca
    33121 gatagctgca aataagtact ttttcccatc catattgata aaaccttgcg tcttttcgtg
    33181 aaaattgacc gtggtattag caggtacaag ccatgctgca ctcagcccta gcaaaacact
    33241 tgaaaaataa aataaaggaa aataaaatac gcctaatatt ccaagcaatg aaccagcacc
    33301 accaatcagc agagcgatca tcagcaacgt gtaactatct agaccaaatc gtagactgtt
    33361 gactaaaaat agtccagtca tccgaaaggc ataaaacagc gtaaatggca aaatcgtcag
    33421 ccaattatgc gagtctgtta gtcccaaaaa taaaagataa ggaataaaaa taaccgtgtt
    33481 acttaagata aagggcgttg tttgtgtaaa attacgccca aatcgtttga gtttttcgaa
    33541 catgacaatg gctccttaaa cagtcttata actaatctgc tcttcgattt tagcattaaa
    33601 ggggaaataa accaatttta cagaatatat tcttgtaaaa aaaaatacag aaagaagcat
    33661 aagcttcttt ctgcattttt acggtacttg attactcaag cagacaagcc cttctccaca
    33721 aaagtcttgc ccgacacccc tgcatccggc aggtgataaa gatagaaatc aattatcctg
    33781 tgcctccaaa atcaattagg agctctgtaa accagagtcc ttctcgaccc gtcgcataaa
    33841 tttactttaa cacagttcct atgtttatgc gagagctttt ttcattttat aatcgaccat
    33901 ttgaaatcct tgaccgatat ctgaaataag ttcttctgta atctcaaatc cttcatgctt
    33961 ataaacctcg attgcttgat gattcccctg attcactcgc aaaaagatct ctctttcctt
    34021 tgtttgcgca gcaagttctt cataccagcg aaaaactgaa gaagtcaatc cttgaccacg
    34081 tactttattt agcaaatata atttacttaa ataaattttt ccatttatct cttcataagc
    34141 agtgtaaccg acagtctttt cttcgctttt taataaaaag taggacacac cttctgtcag
    34201 ttctttttga atctgttttt ttgactgata agttttcagc atgtaatcca cttgtttttg
    34261 accaatgatc ggcacaaaag cttccggcca tacttcttgt atgactgcca tcagctcatc
    34321 cagttcattt tctgttactt ttattttttc catacaccca cgtccttttt tacattataa
    34381 atgaccttgc gcttgatgga ataaaaagag catgatcatg ctatacacac ccaccgacca
    34441 tggtttcaag aaaatcacaa tctgcataaa ttccctaaaa gataatttcg tcaaaccagc
    34501 tactagacag atcaagtcgt ctggcgcaaa gggaagcagc aaggtaacaa ctagtacttt
    34561 tttaatatct ttcgtttttc ttgtcagcaa ttcatcaaat ttctgatact tttttggcga
    34621 taaaataagc tggacaaagg ctacgccata gtaacggaca agcaaaaatc cgattgcttc
    34681 cccaatcact aggccaatac aactatataa aagcccaaat ccattgccaa acatcagcat
    34741 gcccgctact gaggagatcc ctcccggcaa aataggaatg atcacttgga tcacttgcaa
    34801 cagaacaaat atcatcactg catacttgcc aaattgctgg ataaacgctt gcaaagacgt
    34861 gctcgatcga aaaatcccat gatgataagc ataaagaatc aacacaaaga aaaaaaacag
    34921 accaataatg ggcatgatct gaagacattt ttgtaaaact gatccttttt tagacatcta
    34981 tattccccac atcttttttc atttattaaa actgcctcct
//
LOCUS       DAFBSV010000020        34643 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.020, whole genome shotgun sequence.
ACCESSION   DAFBSV010000020 DAFBSV010000000
VERSION     DAFBSV010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34643
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.020"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            598..1287
                     /locus_tag="LLB18_000937"
     CDS             598..1287
                     /locus_tag="LLB18_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5243953.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQLVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1274..2482
                     /locus_tag="LLB18_000938"
     CDS             1274..2482
                     /locus_tag="LLB18_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK5243954.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2776..4047
                     /gene="serS"
                     /locus_tag="LLB18_000939"
     CDS             2776..4047
                     /gene="serS"
                     /locus_tag="LLB18_000939"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBK5243955.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="LLB18_000940"
     CDS             complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="LLB18_000940"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBK5243956.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6585..7280)
                     /locus_tag="LLB18_000941"
     CDS             complement(6585..7280)
                     /locus_tag="LLB18_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HBK5243957.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="LLB18_000942"
     CDS             complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="LLB18_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBK5243958.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8479..8670)
                     /locus_tag="LLB18_000943"
     CDS             complement(8479..8670)
                     /locus_tag="LLB18_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBK5243959.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8691..9581)
                     /locus_tag="LLB18_000944"
     CDS             complement(8691..9581)
                     /locus_tag="LLB18_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBK5243960.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9568..10335)
                     /locus_tag="LLB18_000945"
     CDS             complement(9568..10335)
                     /locus_tag="LLB18_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBK5243961.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="LLB18_000946"
     CDS             complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="LLB18_000946"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBK5243962.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="LLB18_000947"
     CDS             complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="LLB18_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBK5243963.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="LLB18_000948"
     CDS             complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="LLB18_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBK5243964.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14906..15289
                     /locus_tag="LLB18_000949"
     CDS             14906..15289
                     /locus_tag="LLB18_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243965.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15457..16215)
                     /locus_tag="LLB18_000950"
     CDS             complement(15457..16215)
                     /locus_tag="LLB18_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HBK5243966.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16233..17051)
                     /locus_tag="LLB18_000951"
     CDS             complement(16233..17051)
                     /locus_tag="LLB18_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBK5243967.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="LLB18_000952"
     CDS             complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="LLB18_000952"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBK5243968.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="LLB18_000953"
     CDS             complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="LLB18_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBK5243969.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18179..19513
                     /gene="dnaA"
                     /locus_tag="LLB18_000954"
     CDS             18179..19513
                     /gene="dnaA"
                     /locus_tag="LLB18_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBK5243970.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19711..20841
                     /gene="dnaN"
                     /locus_tag="LLB18_000955"
     CDS             19711..20841
                     /gene="dnaN"
                     /locus_tag="LLB18_000955"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBK5243971.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21070..21312
                     /gene="yaaA"
                     /locus_tag="LLB18_000956"
     CDS             21070..21312
                     /gene="yaaA"
                     /locus_tag="LLB18_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBK5243972.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21299..22423
                     /gene="recF"
                     /locus_tag="LLB18_000957"
     CDS             21299..22423
                     /gene="recF"
                     /locus_tag="LLB18_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBK5243973.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22420..24366
                     /gene="gyrB"
                     /locus_tag="LLB18_000958"
     CDS             22420..24366
                     /gene="gyrB"
                     /locus_tag="LLB18_000958"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBK5243974.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24386..26857
                     /gene="gyrA"
                     /locus_tag="LLB18_000959"
     CDS             24386..26857
                     /gene="gyrA"
                     /locus_tag="LLB18_000959"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBK5243975.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27093..27392
                     /locus_tag="LLB18_000960"
     CDS             27093..27392
                     /locus_tag="LLB18_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBK5243976.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27442..27954
                     /gene="ssb"
                     /locus_tag="LLB18_000961"
     CDS             27442..27954
                     /gene="ssb"
                     /locus_tag="LLB18_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBK5243977.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27980..28216
                     /locus_tag="LLB18_000962"
     CDS             27980..28216
                     /locus_tag="LLB18_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBK5243978.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28359..30332
                     /locus_tag="LLB18_000963"
     CDS             28359..30332
                     /locus_tag="LLB18_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBK5243979.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30338..30790
                     /gene="rplI"
                     /locus_tag="LLB18_000964"
     CDS             30338..30790
                     /gene="rplI"
                     /locus_tag="LLB18_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBK5243980.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31064..32431
                     /gene="dnaB"
                     /locus_tag="LLB18_000965"
     CDS             31064..32431
                     /gene="dnaB"
                     /locus_tag="LLB18_000965"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBK5243981.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33211..34503
                     /locus_tag="LLB18_000966"
     CDS             33211..34503
                     /locus_tag="LLB18_000966"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBK5243982.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNCCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10556 a         6734 c         6843 g        10510 t
ORIGIN      
        1 ttcatcagga gtgtttcccg attcgttttt ggctgccgta gcaactttta tatcatatca
       61 gagagacaag taattgtcaa ctctttttta aaagtttttt cgatttcgtt tttcgaaatc
      121 ttccagcaac tcatttatca taacttatcg tttgttattt gtcaagaact tttttgaagt
      181 ttttttcgat agaatcaagc ttcgcaagtg gttctttttt aacgactcag ttatcttatc
      241 atgtcatttc caacatgtca acaacttatt ttttattatt taataagtta ttggtgttct
      301 tttgaacaaa taataatata tcaacatcac atgtgaaagt caataagaaa atgcttattt
      361 atcaacattt ctagcttaca tgatcattgg ttagttctgg tcctttttcg ttcgtcttta
      421 taactccgag agacgtaaaa tccttttgtt ttcagtttaa tgttcatgtt cttgtcttat
      481 tcacaccaac tagatgtctc accttctaaa attttcctta acaaagtgct gcttttatct
      541 atttctgctt ttttttgcta gaataatagt aacaatatga ctctggagga tttatttatg
      601 aaaattttga ttgctgacga tgataaagaa atcgttgaat tattaagtat ctatgttcac
      661 aatgaggggt atgaagcagt aaaggcttat gatgggaaag aagcattatc taaaatcaga
      721 acaatccctg atattgaatt acttatttta gatatcatga tgcctgagat ggatgggatg
      781 caattagtga aagagctacg aaaagaatcc caaataccaa tcattatgct gacagcaaaa
      841 actactgata tggataagat caaaggactg gtcgctggtg cagatgatta tgtgaccaag
      901 ccatttaatc cgttagaagt aatggctaga gtaaagtctt tattacggcg tacaaaaatg
      961 cagattgccc cagatcagcc tgatgtatta gaagtaaatg cattaatcat caataaagac
     1021 tctcatgaag ttaaaacaat cgatgggaaa gaaatccagt taacagcttt ggaattcggt
     1081 atcctctact tgcttgctag tcatcctaat cgagtattta gcgcggatga aatttttgag
     1141 cgtgtttgga aacaagaaag tattgtctct gctaaaactg tcatggttca cgttagtcat
     1201 ttaagagata agattgaaga agcaactggt ggtgaaaaag tcattcaaac cgtttgggga
     1261 gtgggctata aaattgacgc aagatagtaa acgagcaact gaaaaacgcc gtcggatcaa
     1321 tttgacttca aaagaaatca gcgaattgtt agcggaagga atcatcacga ttatcctttt
     1381 gcttctatta aatgtttcta ttctggttgt tatcagttcg gtgatcaaca gttcaccttc
     1441 tttgacgaat gcgatttggg attcaaagaa tatttttgca gaacgattga acactgattt
     1501 gttctggaac ggccggaatt ttattattcc ctttttcttt ctattagata ttggtgtttt
     1561 gtattggcgc ttgattcgaa gatatcgcca aatgcaattg cggcatatca tcagcgaact
     1621 tcactacatc gcaaacggaa attatgatca tcgtatccct tttgaactga gtggtgactt
     1681 aagccgagtg gtaacaagta tcaatggatt ggtggatagt accgtagcag cgattgaaga
     1741 cgaacgtaaa atcgaaaaat caaaagatga attgatcacg aatgtcagtc atgatatccg
     1801 taccccactc acgtccatca ttggatacct aggactgata gaagatggcc agtatcactc
     1861 agaagaagat cttttaaagt atacgcatac tgcttatatc aaagcaaagc agatgaaatc
     1921 tttagtggac gacttatttg aatacactaa ggtacgccag cctgctgtcc cggtgaattt
     1981 ttctgccttt gacatgatcc agttgatcga acagttagca gctgattttg agttggaagc
     2041 ttctaaaaaa aatatccaaa tacttgttca atcaaaagta gactccctta tcatggatgg
     2101 cgataccgaa aaacttgtac gtgtcttcaa taatcttttg acgaatgcgt tgaaatacgg
     2161 aaaaggagca acgaagatcg taatcgaagt agaacgtatc ggttcagaag ttgttgcaac
     2221 agtcaaaaat aacggagcaa tgatcccaca acaggcaatc gataatctat tcgaccgttt
     2281 ttatcgtgta gaagaatctc gttcacaagc aactggagga actggacttg gtttagcaat
     2341 cgctcaaagc attgtggctt tgcacggcgg atacatttat gcaaaatcag ataagcaatg
     2401 gacttctttc atcatgcacc ttccaatcaa gaaaaatgaa aaattaccta ttgatacaca
     2461 ggaagttatt gacgaaagct gaaatattcg ctattcttat tacaattatt agaataaatg
     2521 aaaaacacag aacccagtac actttattct ttttcagaga gctgatggca ggtgtaaatc
     2581 agcaaaggat aatttggaag ttccagttcg tttacgtgcc ctttcgaaat aagaaaggtc
     2641 ggttcaacag ccgttatgtg ttcaacaagt gcagctgacg ctgaacttgg gtggtaccgc
     2701 gaatttcaga ctgattcgtc ccaagaataa tgggatggat cagtcttttt ttattttcaa
     2761 aaaggaggaa atcatatgtt agatgtaaaa atgatgcgac aaaatattga agaagtacaa
     2821 gaaaaattga tgactcgggg cgtaaaaaaa gaaacattag ctgaattcat ggaactagat
     2881 gaaaatcgtc gtaagctact agtcaaaagt gaagaattaa aaaaatatcg aaatgatgtt
     2941 tctgctgaga tcgcccaatt gaagcgtgca aaagaagatg cttctgctaa aatcgctgaa
     3001 atgaaagaag tcggtggcaa catcaaagca ttggatactg aaattgctga agtggatgaa
     3061 aaattgaaac aaattgcaac tactttgcca aaccttcccc atgattctgt gccagttgga
     3121 acagatgaag aggacaatgt agaaatccgt cgttggagcg aaccacgtac atttgctttt
     3181 gaaccaaaac cacactggga aattgcagaa aatcttgata ttttagattt tgaacgtggc
     3241 gcaaaagtag ccggtagccg ttttgtctat tacaaaggat taggtgctcg attagaacgt
     3301 gctgtctaca acttcatgct tgatcagcat atttacgaac acggctatac tgaaatgatc
     3361 actccttata tcgtcaacag taaagcgatg tttggtacgg gacaatttcc aaaattcaaa
     3421 gaagatgttt tccaattgga gaatactgat ctaacattaa tcccaacagc tgaagtacca
     3481 ttaactaact attataatga tgaaatttta gatggtgcag atttacctat ttatttcact
     3541 gcactaagcc ctgcttttcg ttctgaagcc ggaagtgctg gtcgggatac acgaggactg
     3601 attcgtcttc accaattcaa taaagtagaa atggtcaaat tttcggatgt agagcattct
     3661 tacgaagaat tggaaaaaat gacagctgat gcagaagata tcttgaaaaa attgcatttg
     3721 ccttatcgtg tgatggcctt atcaactgga gacatgggct tttctgcagc taaaacttat
     3781 gacttagaag tatggatacc tgcacaagat acttatcgtg aaatcagttc ttgttctaac
     3841 tgtgaagatt tccaagcacg ccgcgcaatg atccgttatc gcgataatga tggaaaaatc
     3901 cactatactc atactctgaa tggttcagga cttgcagttg gccgtacagt agctgccatt
     3961 ttggaaaact accaaaatga agatggttct gtcacagttc cagaagcgct cgttccttat
     4021 atggggaatc tgaaagttat taaataaaga ggctgtgaaa aagccgctta gtttcgagta
     4081 ttaagaaaaa ttttgtgaaa atggctttcc acatttttgc ataaattgga cttaataccg
     4141 agaaactggc ttttgaacac catttatcga gaggttgtga aatcagcgaa ttaacctgag
     4201 tattagagaa aaaaatggaa aaatagtccc tcatatttta ccgtttgttg aactaatacc
     4261 gagggtcagc tgattgaaca ccgtttagtg gagaggtcgt aagcctaccc cccagctcct
     4321 agttacaagg acaaattcaa aaaacagctc ttcatatttt atgaatgttg tacttgtgat
     4381 tcggaggtgg caagggaaca ctgtttattc aaaaagaggc tgggacagaa gcgtttaact
     4441 ccaagaaata agaagaaatt cacgaaaatt gcttttcaaa tttttgtgaa tttcttctta
     4501 tttccgaagg agttgcttct acttccgccg tttatacgtg tttagagcgt gagacaaaag
     4561 tgttctttac ttttgtccca cgctctttaa tgtttttaag attcaactga atagtttggt
     4621 gcttcttttg tgatttgtac atcatgaggg tgtgattctt ttaatccact gccgctcatt
     4681 tggataaatt gcgcttcatc acgtaattgc tgtagattgg ctgccccaac ataacccatt
     4741 cctgaacgca aaccgccgat catttggaaa ataatatctg caacacttcc tttataagca
     4801 acccgacctt cgattccttc tggtactaat ttatttgctt cattgacact accttggaag
     4861 taacggtctt ttgaaccttt ttccatcgcg cctaatgagc ccatacctcg gtatgttttg
     4921 aatcgacgtc cttggaagat ttcgaattca cctggtgatt catctgtccc tgccaacata
     4981 cttcctagca tcactgcatg tccgccggca gctaatgctt tgacgatgtc accagaatat
     5041 ttgatccctc cgtctgcaat aatcgctttg ccatattgac gagcaactga tgctgcatca
     5101 taaatagctg tgagctgagg tacacctaca ccggctacca cacgtgtcgt acaaatcgat
     5161 cctggtccga taccaacttt tacgacatct acacctgcat catataaagc ttttgtcgct
     5221 tcagccgtcg caacgtttcc tgcaatcaat gttgcatctg caaaagttga acggatttct
     5281 tgaatttttc ggatcacacc tgcactatgt ccatgagctg tatcgatgat gattgcatct
     5341 gcccctgctt ctaataaagc attcgcacgc tcaaatgtat cgcttgttac accaacggct
     5401 gctgctacaa gcaatcgacc atgttcatct tttgctgcat ttggaaattc gatcactttc
     5461 tcgatgtctt tgatcgtgat caatccgctt aaacgacctt cgttatctac gattggtaat
     5521 ttttcgattt tatgtttttg caaaatcttt tctgcatctt ttagagaggt acctactggg
     5581 gcagtcacta agttgtcttt tgtcatcaca tcagcaatcg gcatgtgata atctgttaca
     5641 aaacgcatgt cgcggtttgt aattatccct accaattttc tgttttcaag tgtttcaacg
     5701 attggcacac cactgatacg atatttgctc atcaattctt ctgcgtctgc tacaagatgc
     5761 tgtggcgtta agaagaacgg atcaatgatt acgccacttt cagaacgttt gacttttctt
     5821 acttcatccg cttgctggct gatcgtcatg tttttatgga tcacacctag tccgccttgt
     5881 cttgccatag caatggccat cttgctgtcg gtaacagtat ccatacttgc actgatgatt
     5941 ggaatattca acttaatatt tttagctaat tgtacgctca tatccacttc gtttggtaac
     6001 acgtgacttt ctgctggtat caataagaca tcatcaaaag taaatccttt tttcgtgaac
     6061 tttgtttccc agttggacat ttttagtacc actcctctaa tttagtttat ctattaaaat
     6121 aattgatttt ttcatttaag tcaatgatct acttggaatc aagttagctt tctcatagaa
     6181 taccaatata aagcgtttac atctgtgtat attaaaagag attgtaaaaa agctgtcctg
     6241 catcaagtaa taagaacagc caatcaaaaa cagcttctca tgtttttgaa ttggttgggt
     6301 ttattaccgc agatgcaaac ttttgaacac cgtttagtgg agaggctgtg aaaaagctgc
     6361 ttagtttcga gtagtaagaa aaattttgtg aaaatggctt tccacatttt tgcataaatt
     6421 ggacttaata ccgagaaact ggcttttgaa caccgtttat cgtaaaaagg gactgtgaca
     6481 agacttttgt cacagtccct tactattatt taactatgga taaacaaaat gaggttcttt
     6541 actaccccta gatatctagc aaaatagctg atctttttgc tagtttatct tcttgggacg
     6601 gataaacttc caataatccc gtattttttc ttcaagtagt aacggattgc taaagcagtt
     6661 gccccgataa tgataactac tactggatct aatactggat tgataactgg tggcaatagt
     6721 gttgtcgcag aaaacagtac gacccaaaga agtgtcgttc cacctaggat aagcaatgtc
     6781 ttacccattc ctggtttctt gcttcgatct gctccgggat attcatattg atagatgtat
     6841 ttgtacatca tataaaagac ccagccaccg attgcagaac ctagaacgag tgtagaaaag
     6901 ccataagctg gcgttgttcc acgtgaaaac aatccggtaa tcgcaatcat gatacttaat
     6961 agaccaagca acagcaacgt attatctaac cacatcaata aaggggtgga tgaatttttt
     7021 acttctgctg gcttattgat gattgcttcc gttctttcag agactgtccc aaacaattga
     7081 cgggctgttc ttccgccttt ttgttctgca actaaagtag gcagaatgtc atgaagggct
     7141 tttacttttt cttcttcaga caaattcgct gcttctaaag attttttcaa atcaaaaatg
     7201 tactgttgat ttcttttggt taattttgtt tctaaactat tgttttcttt tacgattgct
     7261 cgtaattgtt ctggttccat tatctaatag tcctccttag ccgttccttt tctcaacggt
     7321 cgtcacaaaa gacattctac catattctac agctagtttg atagcccttt tacacattaa
     7381 agcggaataa cattacgtcg ccgtcttgta cgacataatc ttttccttct aatcgaacac
     7441 gtccagcttc ttttgctgca tgcatgtttc cgtaatgatc caagtcttca aaagagacag
     7501 tttctgcacg gataaatccg cgttcgaaat ctgaatggat gattcctgct gcttgtggtg
     7561 ctttgattcc ttttttgaat gtccaagcac gtacttcttg ttccccagca gtaaagtaag
     7621 tagctaagcc taacaaatca taagcagcac ggatcaactg atccaaacct gattcttcga
     7681 ttcctaaagc ttctaaaaat tccgctttgt cttcttcatc taattctgcg atttcttctt
     7741 ctgcacgagc actgaccacg atcacttctg cattttcttc tgcagcaaag ttgcgcactt
     7801 cttgtacata atgattcgcg tctgcatctg ctacgtcatc ttctgagaca ttggctacat
     7861 aaagaattgg ttttgtcgtc aataaaaata gtgatttaac gattttttgt tcttcttcag
     7921 taaattcgat cgttcgggca gattttcctt cttccagtac aggtttgatt ttatccagta
     7981 cagctagttc tgccactgca tctttatctt tggttttagc aacttttgct acacgagtat
     8041 agcgtttgtt gatagattct aagtctgcta acactagttc caagttgatc gtatcaatat
     8101 cttctagtgg atcaacacgt ccttctacgt gagtaatatt atcatcatca aaacagcgaa
     8161 caacgtgaca aatagcgtct acttggcgga tatggcttaa gaattgattt cccaaacctt
     8221 ctcctttact tgcgcctttt acgattccag caatatctgt aaattcaaaa gtcgtcggaa
     8281 cagttttttt cggatgtaca agttctgtta agcgttgcaa acgccagtca ggtacttcta
     8341 ccatccctac gttggggtcg atcgtcgcaa agggatagtt tgctgcttct gctcctgctt
     8401 ttgtgatcgc attaaacaaa gttgattttc ctacgttggg caacccaaca attccagcag
     8461 tcaatgccat aaatttattc actctttctc tgcatttttt tcaattactt tttttaattt
     8521 cttttcaaaa tctcgacggg tcatcatgac gatatgtccg caattcatac atctgatttt
     8581 gatatctgcg cccattcgaa tgacttccca gcgattcgtc tggcaagcgt gaggtttttt
     8641 catttcaacg atatcgtgca agtcgtacat aaaaatagcc tcctttttgt ttattcttca
     8701 tcaaattgaa tattcaagat atcaagaatt cgagtcaaat ctttttgaga aagatattca
     8761 atctcgatct tacctttccc atttttttct tggatagcta cacttgtacc aaatttatcc
     8821 atcaaacgat cttcgctttc tcggatataa tatggttttt cctttgctag ccttgggatt
     8881 tttttctttt cttttccatc attttgattt aactcagaaa caagctgttc cagttggcgg
     8941 acagttaaat tttcagttac tgcacgattg gctaatttca agatcaatgt tttatttttt
     9001 aaacctaaca gcgtacgggc ttgtcccata gataaacgct gatcttgtac catttccttg
     9061 acaagatccg gtaaagaaag caagcgcaaa taattggcga tataaggtct gctctttcct
     9121 aaacgactag ctacttctgc ttgtgttagt ttcaggtttt tcatcagcat ctcatatgct
     9181 tctgcttctt ctaacggatt cagatcttct cgctgcaagt tttccagcac tgctacttgc
     9241 atcatcgctt cttcgtcaaa gtctctaacg atagcaggga tcgtttcttt ttcagctagt
     9301 ttggacgctc gaaaacgtcg ctcccctgca ataatctcat atccttttac tgcggaacgg
     9361 cgtacgatga tgggttgaaa gacacctgat tgttcaatag aattagctag ttcctgcaaa
     9421 gatacttctt caaatgtttt acggggctga tacggatttg gtcgcagctc attcaatggt
     9481 agctggacaa cggtatcatc ttttacatcc accgtctcta agttttctaa atcttgaaac
     9541 agtgcatcga ttcctcggcc taatccttta cttttcttca cgacttacca cttcctttgc
     9601 caatgcttgg tagacttcag ctcctcgaga acgtggatcg tagtcgatga tcggttttcc
     9661 atgactaggt gcttctgata aacgaatatt tcttggaatg atcgtttcgt aaactttttc
     9721 gcggaagtat ttacgtactt cttctacgac ttcatttccc agatttgttc gtgcatcata
     9781 cattgtcagt aagactccct cgatctctaa ttctggatta aagtgttttt ggactaaacg
     9841 aaccgtattc agtaattggc ttaatccttc caatgcgtaa tactcacact gaacaggtat
     9901 caaaatcgaa tcacttgctg taaatgaatt gattgtcaga tggccaagag aaggcgggca
     9961 atcgatcaaa atataatcat actgactgct tacttctgct aaagatcctt ttaatcttga
    10021 ttctcttgcc atcattgacg tcaattcgat ctctgctcct gctaattgga gagtcgcagg
    10081 cacaatactc aaattttcgt gttcagtgat caaagttgcc tcatcaattg gcaattcatt
    10141 gactagaaca tcatagatgt ctcttgtcac atcaggtttt ctgatcccga caccactggt
    10201 agcatttcct tgtgcatcca tatccactag caatactttt ttgccaaggc tagcaagaca
    10261 agcacctaga ttcaccgtcg tcgttgtttt gccgacgcca cctttttggt tcgcaacaga
    10321 tattatttgt gccatctctt ctcctcctat ttgattggct gcttattagg cagtccgggc
    10381 tttcttgggt atttctttgg ggttggtttc tttttttgaa taacgatgat atgccgttga
    10441 tcagagacat tcggcaaggt aaccgcctct tctttgagga atttaccacc taataaagca
    10501 atcgcttgtt ttgcttctgt caattcctct tcactttttg ctgctttcaa tgcataaaaa
    10561 tagccttctt gtttagccaa gggcaaacac aattccgcta acacattcaa acgagcaacc
    10621 gcacgagcag tgacaaggtc aaatgatgca cgaaagtgag gattttgccc aaatgtttct
    10681 gcccggtcat gatataagga agcatcgatt cctaataatc gggttaactc agataagaag
    10741 gttattcgtt tattcagaga atcaacgatc gttatctgca gttctggaaa ggcaattttt
    10801 aaaggtatgc taggaaaccc tgcccccgaa ccaacatcgc ataaagataa aggttgcgta
    10861 aagtctactt caaatgctaa tgtaagtgaa tcgtaaaaat gcttcagata tacgtctttt
    10921 tcatccgtaa tagctgtaag gttcatcttt tcgttccatt cgactaatgt ccgataataa
    10981 atagcgaatt gattcatttg atgatcggta agctctatcc ctttttctgc caaggattgg
    11041 cgaaattctt ctggtatcat aaatattcct ttcattgtga aacagcaatt gtttcacaga
    11101 ttctctccct actttaacgc aaaatctcta gacatgcaat ccttccatat ggattcttaa
    11161 aaatttgaaa agtaagaaaa gccgatagac tttttctttc tagtatgact cataaaatat
    11221 acacagaaga gagaactagc tttgagcaat ttctgcaaaa actagttctc tcttctattt
    11281 attattacgt attacgctgg ttcactgact ttcgcaatct tcccttgttc gatatagacc
    11341 attaggatac ttaggtctgc agggtttacg ccactgattc ggctagcttg ggcaattgtt
    11401 tctggttgga ttttctgcaa tttttgtttt gcttctgttg ctaatccgtt gattgctgcg
    11461 tagtcgatgt tttctggaat ctttttcgct tccatgcgtt ttaatttttc tactttttcc
    11521 atggcttttt tgatgtagcc ttcatatttg atttggattt ctacttgttc gatttctttt
    11581 cgtgtcaatt cttcattttc tggaataaac cgtagaagtt ctgcataagt aatctcagga
    11641 cgtcttaaaa agtcgcttgc tagtacacca tcttttaatg gtgccgcatt aatcgttgct
    11701 aaaaagtctt ggacttcttc tgttggtttg attcgtacat tcatcaaacg tttgatttct
    11761 tgttcaactg cttctttttt cttcaaataa ttcttgtatt gatcttcttt tactaagcct
    11821 acacggtgac ccatttctgt taatcgcaaa tctgcattat catgacgtaa aagcagacgg
    11881 tattcagcac gtgaagtcag caaacgataa ggttcgttcg ttccttttgt taccaaatca
    11941 tcgatcatga caccgatgta accgtcactt cgtttgatca ctaaaggttc ttttccctga
    12001 actttcaaag ctgcattgat accggcaatc agcccttgtc cagccgcttc ttcataaccg
    12061 cttgtaccat ttgtttgtcc agctgtataa agattttcaa cgactttagt ttctaatgtc
    12121 ggacggagct ggtgtggctc tactacgtca tattcgatag catatcctgt acgcatcatt
    12181 tctacttttt ctaatccagc aatagaatga agcatgttga cttgaacatc ctctggtaaa
    12241 gaagtagata aaccttgaac atagacttct tccgtattta agccttctgg ttccaaaaat
    12301 aattgatgac gtggtttgtc tgcaaaacgc acgatcttat cttcgatgga tggacaatag
    12361 cgagcgccta ccccttcaac gatccctgta aacattgggg cacgatgtaa gttgtctcga
    12421 ataatttggt gagtcgtctc acctgtatag gtcagccagc aagattcctg atctagttta
    12481 taggcactat ctggtgtgct gaagctaaaa tgattcggct ctttgtcacc aggctgctct
    12541 tctgtaacag aatagtcgat cgtacttgat tttactcgag gcggtgttcc tgttttgaac
    12601 cgttcgatag caaagccaag ttcttttaga tgattcgcta gtccaataga aggttgagag
    12661 ttattcggac ctgatgaata tttcaattca ccgataatga tttctccgcg aagtgctgtt
    12721 ccggctgtaa taacaactgc tttggcccgg tagctcgctc ctgtggacgt cactactcca
    12781 tgacaaacac catcttcgac gatcagttct tcgacgattc cttgtcttag cgtcaaattt
    12841 ggttcttttt cgatcgtatg tttcatttct gttgaataag catgtttgtc tgcttgtgct
    12901 cgcaatgctc ggacagctgg gccttttcct gtgttcaaca tacgcatttg gatataggtt
    12961 ttatcgatat tcttacccat ttctccgcct aacgcatcga tttctcgaac gacaacgcct
    13021 ttagctggtc cgcctacaga aggattacat ggcatgaatg ctaccatgtc caaatttatt
    13081 gtcagtaata atgtttttga tcccatacgt gcagcagcaa gtgcagcttc tgaaccggcg
    13141 tgtcctgcgc caacaacgat cacgtcatac gcatctgctt cataatgttc caatcgtttg
    13201 ttcctccttt tattttccta aacaaaattg actgaataat tgagtgatta gctcatcttg
    13261 tacactgtcg ccgacaactt ctcctagata gtcccagcaa cgcgtcatat ctatttgaac
    13321 gagatccaca ggcattcctg aatcaatacc tgcaatgact tcttcaagtg agagggaagc
    13381 tttttctaac aacgcgatat ggcgggtatt agaaacataa gtagcgtctc tttctcctgt
    13441 ttctccgctg aagaataaat cagaaatagc tgattccaaa cgatctagtc cgtcgttttt
    13501 agctacggaa attgaaaaaa ctggttcatt ttcgatcaat ttcttcaatt tttcttgttc
    13561 cagctgtgct ggcaaatctg ttttatttag aagaatgatc cgtttcaatc cacttgtcgc
    13621 ttccaataat tgttcatctt ctgctgtcag tggttcgctt tggtttagaa caagtaagat
    13681 caagtctgct tctgctaatg cttttcggct tctttcgacc ccgatccgtt ccaccacatc
    13741 ttctgtttcc cgaattccag ctgtatcgat tagcttgagc ggtacccccc gaacattgac
    13801 atactcttcg attacatctc gagtcgttcc tgcaatatcc gtaacgattg ctttttcttc
    13861 tcttaacaaa tggtttaaca aacttgattt gccgacattt ggccggccga tgattgccgt
    13921 acttaaccct tcccgcagaa ccttcccttg cttggatgta gcaagtagcg cttggattct
    13981 ttgttggatc atctgcgctt tttcaagcaa taacttcgta gtcaattctt cgacatcatc
    14041 atattctgga taatcaatat ttacttctac ttgtgctaat gtctctaaaa tctcttgtct
    14101 caatgagcgg atcaaagcag acagattgcc gtctaactga ttaagagcta gtcccattgc
    14161 tttgtctgtt tttgcccgaa tcaaatccat cacagcttct gcctgtgaaa ggtcaacacg
    14221 accattcaag aatgctcgtt ttgtgaattc gcctggctca gctaatcttg caccttctct
    14281 taacaatagc tgcaaaattt gattgactac aacgatccca ccgtgacaat tgatttctac
    14341 tacatcttcc cgcgtaaatg tctttggtgc tctcatcacg gagaccatga cttcatcgac
    14401 aagctgattg ctcttgggat caacgatatg tccataatgg atcgtatgac ttggtacttc
    14461 tgataatcgt ttgtttccag attgataaac tttatctgct agttgcacag cttgatcgcc
    14521 acttaaacga acgatactga ttgcaccttc tccaggtggg gtagaaattg ccgcaatcgt
    14581 atcaaattct aaagtaattt cagccatttt ttcacttcct ttttcatttt gcgcacaaaa
    14641 aaagtgccca ctccaccctt tatgcacaat aaacggtgaa cttcgcactt tgactgcttg
    14701 ttcttgatta aattctggtc atagattatc acacttgcta taaggaatca agtgtttaaa
    14761 acaattagat gaagttgagc ctgttctgct tccattacct tatatttaat tgtccttgga
    14821 tgtctctttg cgttctttgg tttattcgaa gagaagatac tgtataaaca aggctttatc
    14881 tttcttaaaa aaaacggtac actaaatggt agcgctatct aaactataca cttttgaaag
    14941 gagaaaatat gtgagcccgt tcagatctgc tgcattggaa gaagaaagtg accctcggat
    15001 caacgatgtc gttttatcta cagggaatat caaccagaaa tatatcgtcc gcgatatcgt
    15061 ttttgttgtg gaatgcttag aagctgattt gtttgaccca tcttttccca aagatgacct
    15121 tttcttaaca acgaagagga aattaaagac gaaggtactt gaatatggtg cgaatgcagt
    15181 aatcaactgt cattttgagt atcagcaaaa aaaacgcgac ggaaagtatt ttctggaact
    15241 ttttgcttat ggaacagtga tccaatttat ccaaacaacg attggttaaa tgaaacagac
    15301 aaaaaaagcg gatcaaaact gaagacagtt tcgatccgct tttttctatc aaagttagtg
    15361 actacttcat cgtatactct gataagaatg atttctagta aaatatactt ggtttgaaaa
    15421 actttgtcaa cgtgatttat tcaaaaagta atggaatcaa taatattttt tagcaggttc
    15481 tactactaaa taacgataag gttcctcacc ttccgaatgt gtttttacat gttcatcttt
    15541 gcttaatgca gcatggattt gtttacgttc aaatgcaggc attggttcta agaaaacagg
    15601 ctgccctgtc cgttttactt tttcagccgt gcgatcagct aaacgctgaa tgatctcttg
    15661 gcgcttttca cggtaattgc ctacattgac tactacagac agcttatttc ttgctaaacg
    15721 atggatgaag acttgtgcca gatattgcaa tgcattcagt gtttttccat gtttcccaat
    15781 cagtatgcct tgcttttgtg tttctaaatg gaaaacaacc atattatttg attctctttc
    15841 cattttgaca agagctggag catcaagctg ttttgaaatt tcagtaagat aaactgccaa
    15901 ttccgttaaa gctgcttcat cacctagctc acttacttct tctgtttttt cttcaagaat
    15961 cgtttcgttg actacctcga tctcagctgt tggttcttct tccaaaattt cttctacagt
    16021 ctgttctact gtttcagaaa ctttttcgct gatacttggc tggatcgaaa gccgtgcatt
    16081 ctttcgaccc attcctagga aacctttttt tccttcttcc agtatttcga tttcgacttg
    16141 gtctttggcc aaacccaaat cagccagacc tagttggaca gcttcgtcta ttgttgcagc
    16201 ttcataaatc ggcattagca ttacctcccc tattatttcc gttttttctt aggattcatt
    16261 gctttcttaa gagcacgttc tctttcgcgg attctccgtg cttcttcttc acgctctttt
    16321 cgaattttga aagggttgtt gatcagcagc gtttgtacaa cttggaaggc attggaaact
    16381 acccagtata atgaaagacc gctggctaaa ttgacaccca tcactaaaat cattacaggc
    16441 atcacgaaat tcatgatctt cattgatgca ttcgattcaa tttgactcat gctagataaa
    16501 tacgtacttg caaaagtaaa gattgctgct aaaatcggca aaataaatgt tggatccgcg
    16561 ttccctaagt tcaaccataa gaaatgccct tgtttcaact ctggtacacg tgaaatagat
    16621 tgccataacg ccatcaagat tggcatttgt actaataaag gaagacaacc agcatatgga
    16681 ttgacgccat tttctgcata taaacgctgc tgctcttctc ttaacttact ttgtgtttcc
    16741 ggatctcttg aactatattg ttgctgcagt gcttttaatt tcggttgtaa ttcttgcgtt
    16801 ttacgcatgc tctttgtttg gaaatgcatc aacggcaata ggatcacgcg gatgatcagt
    16861 gtaaataaaa tgatccctat ccctgcatta ccaaatgaca acgccttgat cgcctcagca
    16921 aagtaataaa caatataacg atcccaaatt cctgtactct gtgcgctgac ttccccagtt
    16981 ccgcaaccgg ataagacgat gaccaaacta acgataccgg ccatcaaaag taaacgtttg
    17041 tatttcttca cttactcttt tcctctctgt cgattatttt tgcaagtttt aagacgtgga
    17101 ctaaattgga gcgaacctca tcataagtca accccttcac acttggtcta gcaatcacaa
    17161 taaaatccaa ctccggatca atttcttctt ttatagaata aactgctgct cggatttttc
    17221 gtttgacttc attgcggttt accgcgttgc cgaccttttt tcctacagat aaaccaactc
    17281 gaaaatgagg ctgtcccggt ttttccaaac ggtaaacgac gaatttgcgg ttagcaaaag
    17341 aatctcccgt atggaacacg gcttgaaact ctcgttcttt ttttactcga tacgcttttc
    17401 tcattagttt tctttccttt tctatctctc acttacgctc ataatcatac cataattacg
    17461 attgtccttt catcatttcc ctaaaaaaga gtataaaaaa aaccactgaa accccagtgg
    17521 cctaagctga aagaactttt cttcctttgc gacgacggct agctaacaca cgacgtccat
    17581 ttttagtact catacgttta cggaatccgt gaactttttg acgtttacgt ttatttggtt
    17641 ggtatgttct tttcatatat tccacctcca aaatgttctt atctatttta taaacacaga
    17701 catactttga tagtataacg acaaagtagt gattttgtca atataaaata gaagatcgat
    17761 tgttaaaact tatccacaag attatttttt tctatgggaa tcctatgtgg aaaaagttat
    17821 gcacagggat tatccacaga taataaaagg ctggttttac acagaaaaca cacgtgtaaa
    17881 aaaagtaatc cacaatcagg cgatttcctg tgtattccgt ctcctaacta ttggtatatc
    17941 tgtatttttt atccacagac gcaagaggaa atctattggt ttttacgagt tttccacctg
    18001 tgcattagtg gtgtggaaaa ctttttttga caactgtgtt tttctctttt ttctttttgt
    18061 cgattgtgtg gataattgta attaaaaaat ttttttcttc ggtttctgtg gaaaactatt
    18121 gaaaaaaatg ctaaattagt actagttatt cactttttaa tgaaggagga ggccttatat
    18181 ggtatccctc gatgctttat ggaatgaatt aaaagcaaca taccaaaagg atttatcgcc
    18241 tgctagctat aatacatgga tcgaaacagc gaaccctcga acccttgatc aaaaccagct
    18301 cgttgttgag gttcctagca agattcataa agaatattgg gaaaaaaacc tggcgacaaa
    18361 aatcgttgaa gtcggttata tgttatcagg aaatgagatt atccctcgct ttattactgg
    18421 cgaagaagca gagcaagaag aagttataga agaaaaaaat ccaaaagttg tggcacctag
    18481 tccgctaaaa aaagccatgc tgaaccctaa atataccttt gatacgtttg tcattggtaa
    18541 aggaaaccag atggctcatg cagcagcgct cgttgtagca gaagatccag gttctattta
    18601 taacccgctc ttcttttatg gaggcgtggg acttggtaag actcacttga tgcatgcaat
    18661 tggtcatcaa atgctgcaaa gtcagcctaa tgccaaagta aaatatgtaa gcagtgaaac
    18721 ttttgctaat gatttcatca attcgatcca aaacaaaaca gcagaagagt tccgtcaaga
    18781 atatcgaaat gttgatttac tgctagtgga tgacattcaa ttttttgcag aaaaagaagc
    18841 tacgcaagaa gagtttttcc atactttcaa tgccttgtac aatgaaggga aacaaatcgt
    18901 actaaccagt gatcggttgc caaacgagat tccgaaactg caagaacgcc ttgtttctcg
    18961 ctttgcatgg gggctgtctg ttgatattac accgccggat cttgaaacaa gaacagcgat
    19021 tttacgtaaa aaagcggcgg ctgaacgtct agagatccca gatgacacac taagctacat
    19081 cgcaggacaa attgattcta acattcgtga attagaaggt gcgcttgttc gagtgcaagc
    19141 ttttgctgcg atgaatagtg aagatatttc gactagtcta gctgcagacg cactgaaaac
    19201 gttaaaatca ggaaaaggac atcctcaatt gtcaatcctg cagatccaag aagaagtggc
    19261 aaagtattat cacatccaat tgaaagatct caaaggaaag aaacgcgtca aatctattgt
    19321 tgttcctaga caaatcgcta tgtatttggc acgtgagctc acagataatt ctttaccgaa
    19381 aatcggagct gaattcggtg gcaaggatca tacaacggtt atccatgctc atgaaaaaat
    19441 ccagcagctg atggattcta gtgtcagtat gcaaaatgaa gtatcagaaa tcaaaaactt
    19501 tttactaaat taatttgtcg attctatcaa ctgaaaatag catgtggata aaagaaaaaa
    19561 acgttcaaaa gttatacaca ctttttccac agctgttttt tcgtttctct cttacgtttt
    19621 ttgagttttc cacagaatca acatgcccta ttacttttat tattcttttt aactaataat
    19681 aaataaacaa acattcaaag gagatacatc atgaaagtta ctttaaaccg agctagcttt
    19741 atgcaggaat tgcaaactgt tcaacgagct atttcaagca aaaccacgat ccctattttg
    19801 acaggtgtaa aaatcacact gacacaagaa ggtttgactt tgacggggag caacgctgat
    19861 atatcaattg aaactttttt gtctgttgaa aacgaaaaag caaatatgca aatcgaatct
    19921 actggttcca ttgttttaca agcacgtttc tttagcgaaa tcattcggag acttcctgaa
    19981 gaaacattta ctttagaagt tttagaaaat aaacaagtag cgatcacttc tggaaaagcg
    20041 aattttatcg taaatggatt agatgcagat aactatcctc atcttcctgt tgtcgaaagc
    20101 cataaccaga tgaaattacc tgtacacgta ttgactaaac taatcaacga aacagttttt
    20161 gctgtctcac aacatgagag tcgtccaatc ttgacaggtg tgcatttcat tttatctgat
    20221 aattctttat tagctgtagc tactgattct caccgtctaa gtcaacgcgt gattccagta
    20281 gaacaagcgg ctgatcattt tgatattgtt attcctggaa aaagtttgat cgaattatct
    20341 cgctcattaa caaatgaaga agaaatcgtc gaaatcagca ttatggaaaa ccaagtgttg
    20401 ttcaaaacag aaacgatgta tttctattcc cgtttgctag aaggaaacta tccagatacc
    20461 aatcgtttga ttccttcaag ttttaataca gaggttgaat tttctgttcc tagcttttta
    20521 gcggcgatcg aacgggcttc tttactttct catgaaggcc gtaacaacat cgttcgttta
    20581 tctattcgtc cagatgcggt tgttttatac ggaaattcgc cagaaatcgg gaaagtagaa
    20641 gaaagcttga gttatacagc aagcagtggc gatccattag atatttcttt caatccggat
    20701 tatatgaaag cagcgttgcg tgcatttgga gatatgagca tcaaagtgaa atttatctct
    20761 gctattcgtc catttacatt ggaaccaacg gaagatggcg ttcaatttat tcagctgatt
    20821 actcctgtac gtacaaatta acaatgattt tcaatgttct tgaaaattta attgaaaaga
    20881 aatagaaaaa ataaaatttt aaacagaagg ccctaaaatc tcttttaagg ctttctgttt
    20941 atttttgttt aaatcacctt ttttagatta aatcgtctta tatggaaaaa tatatggata
    21001 aatttgtttt attgcgaaaa aaaaggtata atagagtata cttttaataa tgaaaatgag
    21061 ggatgggcat tgaaacaaca agtcattcta aatacggaat tcatgacgtt gggccaaatg
    21121 ttgaaagaag tcacagttat cggtagtggc ggacaagcaa aatggtattt ggcagaaaac
    21181 actgtgttag tcgatggcga accagaaaat cgtcgtggac gcaaacttta tcccggcatg
    21241 atggttgaag ttccagaagt aggaactttt tttatggtaa aaaaaggaaa cgacgataat
    21301 gaggctgaat aagctgtatt taaaaaatta tcgaaattac gaagagctga acatcgaatt
    21361 ttccaagaac ctcgtcatct ttttaggaga aaatgcgcaa ggaaaaacga atcttttgga
    21421 aagtatctac gtattagcta tgacgcgaag tcatcggaca agtagtgagc aggaattgat
    21481 tggctggact gacgatcagg cgatgattca aggagagatc acaaaaggtt catccactct
    21541 tccattagaa atcttattat ctaaaaaagg ccgaaaaacc aagatcaacc atatcgaaca
    21601 gaaaaagtta agtacttacg tgggacaaat gaatgtcatt ttatttgcac cagaagatct
    21661 ttctttagta aaaggcagcc cgcagaccag gcggaagttt ttagatatgg aattaggcca
    21721 gatcaatcca atctatcttt atgatcttgt ccaataccaa gcaattttga aacaaagaaa
    21781 ccagtacttg aagcaattga atgaaaaaaa acaaactgat ttgctttatt tggatatttt
    21841 gtccgaacaa ctagcagcgt ttggcagcaa agtattgaaa gcaagagcac agttcgtcaa
    21901 gcgattggag ttttgggcta attctttgca tcagcaaatc acccatcaaa aagagcagct
    21961 ggaaatcgag tatctcaccg cagtcgattc tttagaaaca catacgcaag agcaaatcca
    22021 agaacaattt ctcgcacttt tgaaccaaaa taaaaagaaa gacctttttc ggggaacaac
    22081 gacagttggt cctcatcgtg acgatctttc cttttttatt aatcagaaaa atgtgcagac
    22141 ttatggatcg caaggacagc aaagaacaac tgcactaagt gtcaaattag cagaaatcga
    22201 tttgattaaa gaagagacag gggaatatcc aatccttttg ttagatgatg tgatgagcga
    22261 gctggatgat aatcgtcaac tccatctgct agaaacaatc gaaggaaaag ttcaaacgtt
    22321 cttaacaaca acgacacttg accatgtaaa aaataaaatg actgttgaac ctgagatttt
    22381 ttatgttcaa caagggaaac taaaaggaga agaaactgaa tgacagaaga aagaagttta
    22441 gtagaacgcg ctaaagagta tgatgccagt cagattcaag tacttgaagg acttgaagcc
    22501 gttcgtaaac gacctggcat gtatatcggt tcgactagtt ctgagggtct gcatcacctt
    22561 gtttgggaaa ttgtcgataa ttcgatcgat gaagtattag caggttttgc aacgaaaatc
    22621 catgtgatta ttgaaaaaga caacagtatc accgttattg acgacggtcg ggggatacct
    22681 gtagatatcc aggcaaaaac tggacgtcct gcagttgaaa cggtctttac tgttttacat
    22741 gctggaggaa aattcggcgg tggtgggtac aaagtttctg gtggacttca cggagtagga
    22801 tcttctgttg ttaacgcgct ttctacacag cttgatgtca aagtatacaa agaaggaaat
    22861 gtgtactatc aagaatatcg tcgtggagct gtagtggacg acttaaagat tatcgaacaa
    22921 acggatcgcc atggaacaac ggttcacttt acgccagacc ctgaaatttt tacagagaca
    22981 actgagtttg atttttcaaa attggctacc cggatccgtg aacttgcttt cttgaaccgc
    23041 gggatgcgta tatcgattga agacaaacga gaagaagaac cagtcatcaa tgaataccat
    23101 tatgacggcg ggattaaaag ttatgtcgaa tacttgaatg caaacaaaac cgtgattttt
    23161 ccagaacctg tatatttgga aggtgaacag caagatatcg cagttgaagt ctctatgcaa
    23221 tatacagacg gctaccattc caatatcatg agttttgcca acaatatcca tacgtatgaa
    23281 ggcggaacac atgaatcagg attcaagact gctttaactc gtgtgataaa tgattatgcc
    23341 cgaaaacaaa agctgatgaa agaaaatgac gacaacttga ccggtgaaga cgtgcgagaa
    23401 ggattgacag ctgttatttc tatcaagcat cctgaccctc aattcgaagg acaaacaaaa
    23461 acaaaattgg gcaattccga agtacggaca gtcactgatc ggttatttag cgaacatttc
    23521 atgaaattct tgctggaaaa cccaagtgtg ggccgtcaaa ttgttgaaaa aggattacta
    23581 gcttccagag ctcgtctagc agcgaaacgt gcgcgtgaag taacgagacg taaaggtgct
    23641 ttagagatta gtaatctgcc aggaaaatta gcggactgct ctagcaacga tcctgaaaaa
    23701 tgcgaattgt tcatcgtcga aggagattcg gccggcggat cagctaagca aggtcgtaat
    23761 cgagagtttc aagccatctt gcctattcgt gggaaaatct tgaatgttga aaaagcaagc
    23821 atggacaaga tcttggcaaa tgaagagatc cggtctttat ttactgctat gggtacaggg
    23881 tttggagaag attttgatgt atcgaaagct cgctaccaca aattagttat catgactgat
    23941 gccgatgtcg acggcgcgca tatccgtaca ttgctgctga ctctttttta tcgttacatg
    24001 cgtcctattg ttgaagctgg atacgtctat attgctcagc cacctttata cggggtaaaa
    24061 caagggaaga atattacgta tgtacaacca ggaaaaaatg cagaagaaga gttgaaacaa
    24121 gtcgttgctt cacttcctgc ctcaccaaaa ccaagcgttc agcgttataa aggacttgga
    24181 gaaatggatg atcatcaact atgggaaaca actatggacc caagcaatcg gatgatggcc
    24241 cgcgtcagtg tggacgatgc tattgcagca gatcagatat ttgaaatgtt gatgggggat
    24301 cgagtagaac cccgtcgtgc attcatcgag gaaaatgcac actatgtgaa gaacttagat
    24361 atttaatcat gaaggaggaa aaagaatgag tgaagaaatc agagaaaaca tccatgatgt
    24421 caatctaacc agcgaaatga aagactcctt catcgattat gcgatgagtg ttattgtcgc
    24481 acgtgcactt cctgatgtca gagatggtct gaaacccgtt catcgccgta ttttatacgg
    24541 catgaacgaa ttaggtgtaa caccggataa agcccataaa aaatctgcca gaatcgtcgg
    24601 agatgtcatg ggtaaatacc atcctcatgg agactatgcg atctatgagt caatggtacg
    24661 gatggcacag ccattcagct accgttatat gctagtggat ggtcatggaa actttggttc
    24721 tgttgacggt gacggtgccg ccgctatgcg ttataccgaa gcacggatga gcaaaatcgc
    24781 tacagaaatg ctgcgtgata tcaataagaa cactgttgat ttccaaagca actatgatga
    24841 tacagaaaaa gaaccagttg tactacctgc tcgcttcccg aatcttttag tgaacggaac
    24901 aacggggatc gccgtaggta tggccacgaa tatcccacct cataacttgt ctgaggtagt
    24961 agcggctatc gatttgctga tggataatcc tgatgtgacg accaatgaat tgatggaagt
    25021 attacctgga ccagattttc caacaggtgg tttggttatg ggaaaatcag gaatccgaag
    25081 agcgtatgaa acaggtaagg gttctattac cgtacgtgca aaagttgaga ttactgagat
    25141 gccaaatggt aaagaacgga tcatcgtgac agaattgcct tatatggtca ataaagcaaa
    25201 attgatcgaa cggatttctg aactgcacag agacaagcgt atcgaaggga tcacagattt
    25261 gcgggacgaa tcttcccgtg aaggtatgcg gatcgtcatt gacatccgtc gtgacgccag
    25321 cgcatctgtt atcttgaata acttatataa attgacatcc ttgcaaaatt catttggatt
    25381 caatatgttg gcgatcgaaa aaggtgtgcc gaaagttttg agcttgaaac aaattcttga
    25441 aaactatatc gaacatcagc gcgaagtcat cacaagacgg acagtctttg aaaaagaaaa
    25501 agcagaagca agggcacaca ttttagaagg tttgcgtatt gctttggatc atatcgatga
    25561 aatcattgcg attatccgcg ggtctaaatc agatgacgaa gcaaaagcga cgatgatcga
    25621 acggttcgat ttatccgatc gccagtctca agctatttta gatatgcgtt tacgccgatt
    25681 gaccggtttg gaacgggaaa aaatcgaaaa tgaataccaa gaactcttaa aactgattga
    25741 agatttaact gacattctgg caagaccaga acgtgttaca gaaatcatca agaatgaatt
    25801 agcagacttg aatcaacgat ttggtgataa acgacgcaca gaattactag tcggtgaggt
    25861 cttaagtctg gaagatgaag atttaatcga agaagaagaa atcgttatta cattgacaaa
    25921 caatggttac atcaaacgtt tggcaaataa tgaattcaga gctcaacgaa ggggtggacg
    25981 tggtgtccaa ggaatgggta tccacaatga cgacttcgtc aaaaatctgg tttcttgttc
    26041 tacccatgat acattgttat tctttacgaa taacggaaaa gtgtatcggg caaaaggata
    26101 cgaaattcca gaatacgggc gcacagccaa aggaatacca attatcaatt tactaggtat
    26161 cgattcgagt gaaagcatcc aggcaatcat tgcggtgacg ggagaagcag aagaaggcca
    26221 ctatctcttc tttacgacgc gtcaaggtac agtaaaacgt acttctgtca ctgcttttgc
    26281 taacatccga agtaatggtc tgatcgcaat tggtttgaaa gaagacgatg agctcgtcaa
    26341 tgtgctactg acagatggtc aatctaatat cattattgga acacataacg gctactctgt
    26401 cactttcaaa gaagaagcag tccgcgatat gggacgtaca gcttccgggg ttagaggaat
    26461 acgcctgcgt gaggaagatt atgtcgttgg ggcagcctta atgaaggaag atcaagaagt
    26521 attagtgatc acagaaaaag gttacggaaa acggacaaaa gtatcggaat atccagtgaa
    26581 aggccgcgga ggtaaaggga tcaaaacggc gaacatcact gaaaaaaatg gtccactagc
    26641 tggattgacc actgtttctg gagatgaaga catcatgctg attacagata aaggtgtcat
    26701 tatccgtttc aacgtatcga ctgtttctca aactggacgt tcaacattag gcgtacgttt
    26761 gatgaagatg gaagctgata cgaaagttgt cacgatggca gcagtcgaac cagaagctgc
    26821 agaacaaaca gttgaagaac aaggatcaga agaatagcca tcaagactaa ttgtgtaagc
    26881 tagcaagaat gaccgattaa aaaatctggt tattcctgct ggcttttttg attagttgaa
    26941 tttctcttaa aatattcgaa actgttcatt ctgtattgct tttgaccaaa atagagtgta
    27001 taatcagagc ttgtgagtag tctaattaat tagataactc tccttgctct taggaaccta
    27061 agagccgaaa gtccacaggg aggtgaatat caatggaaaa cacgaaatat gaaatcatgt
    27121 acattattcg tccaaacatt gatgaagaag caaaaactgc tttaatcgaa cgtttcgatg
    27181 caatcttgaa agataacgga gcagaagtta tcgaatcaaa agattgggaa aaacgccgtt
    27241 tcgcttatga aatgaacggt taccgtgaag gtatctatca catcgttaaa gtatcttctc
    27301 catcatcagc aaatgctgtc aatgaatttg accgtcttgc taaaatcaac gacgatatca
    27361 ttcgtcacat gattgttaaa gaagaagctt aattgttgtt tcatgtgaaa caatagaaaa
    27421 cgatgagagg agatgactat tttgattaat aatgttgtat tagttggacg tctgacgaaa
    27481 gatccagatt tgcgttacac agcaagtggt acggcagtcg caacatttac tttggctgtg
    27541 aatcgtaatt ttacaaacca aagcggcaat cgcgaggctg attttatcaa ctgtgtgatt
    27601 tggcgcaaat cagcagaaac tttagcaaac tatgctcgta aaggaacact tttaggtgtt
    27661 actggacgta tccaaactcg ttcttatgat aatcagcaag gacaacgtgt atacgtgaca
    27721 gaagtagtag ctgacaactt ccaattgctg gaaagtcgtt ctgcatctga aaatcgccaa
    27781 caaagcggcg gattccaaag ttctggtcaa tcagctggcg gatttggcgg aaacaataac
    27841 tctaatcaaa catctcaatc atccaacggt atgcctgatt tcgaccgtga tacttctgac
    27901 ccattcggct caagttcaac gatcgacatt tcagacgatg atttaccatt ctaaacgaat
    27961 ttgataggag ggaaatagaa tggcacaaca aagaagaggc ggacgtaaac gtcgtaaagt
    28021 agactacatt gctgctaacc atattgaata tatcgattat aaagatatcg aattactaaa
    28081 aagatttatt tcagaacgcg gtaaaatctt gccacgtcgt gtaactggta caggcgctaa
    28141 aaaccaacgt aaaattactg ttgcaatcaa acgcgctcgt atcatgggct tgctaccttt
    28201 cgttagcgaa gactaataaa tcctaggaat tgaatgactg atccttttga tcagctattc
    28261 aattcctttt tttctgtaaa aataacctct attcgtttag tcgctcgaat gacgaaagtt
    28321 atggtaaaat caaattagtc atatatggga ggaaaattat ggaaaataaa aacaatcatt
    28381 tatccccgaa acctctcttc cttatcctgt ttatattaat cgaagtattg gtagtcttaa
    28441 ttttaccatt tcgttttgtt agcgcttcgg tcattctatt gatgaattta tggggtgttc
    28501 gctattggtt gaaaatgaaa cgttggctta ttttaaataa acgtgaaaaa atccagcagg
    28561 cttcgactgt agctgaaacc aatctagctt atgtctcaga agtcatgcct gtaggagtga
    28621 ttgcttatca gccatcaagc caaaaaatcg aatggctcaa tccattagca ttgaaaatca
    28681 aagatcaaag tggattaaca gaggaagaat tgctagatac tttttttact gcaaaagaaa
    28741 aaaagaaaaa ccaagtctat ctagcagata aaacatttca gtttgatatg gatacagtaa
    28801 agggtgttgt ttattttaat gatattaccc aaaaccagtt gttaaaactc catcagacga
    28861 acagtcagcc ggtgattggt attttatcta ttgataacta tgcagatgcc attgataaat
    28921 tggatgacaa agagatttct tatttgaact ctttcgtcac tacactagtt tctgactgga
    28981 tgaatgaata ccatgtcttt ttcaaaagaa tcaacgcaga acggtttttc ttcgtagcac
    29041 agatgatcga tctgaaaaag atgatggata aaaaatttga tttgctggat cgctttcgag
    29101 cagaagctga aaaacagagc tcgcctatca cccttagtat ggggattgct tatggctcaa
    29161 gaaccctcga tgaaatcggt ggagaagctc agaataattt agatgttgct ttagtccgtg
    29221 gaggcgacca agttgtcgtg aaagaggtaa aagaaggagc aaaacctgtt tattatgggg
    29281 ggaaatctgc taagaatgtc aaacgcacgc gtgttcgttc tcgagcgatg agtaccgctt
    29341 tgcgtcggat ttttgatgaa acaggcgatg tgtttatcat ggggcacaag tttccggata
    29401 tggatgcttt aggctctgct tttggtgtca gttgtctggc acgcttcaac cagaaaaaag
    29461 cttacatcgt tatcaacgag aacgagatca ttccagatgt agaacggtgt cttgaagaaa
    29521 tccataagca tcctgaatta gaaatgcaac taatctctcc agaacgtgcc atagagctga
    29581 aaaaagaaga ggacctcctc gtgatggtgg attaccataa accttctcta tcgatctctc
    29641 agggcctata tgagcaattt gataagattg tgatcattga tcaccatcgt cgtggggaag
    29701 agtttccaag taaacctctg ctgacttata tcgaatcttc agcttcttca gcttcagagc
    29761 tagtttctga gctgatccaa taccaaagca gcaaaacaaa tcgcttagat cgttttgagg
    29821 ccacattatt gcttgcaggg atggttgtag atacaaatag tttcaatgtc cgtacaactg
    29881 cacgaacttt tgacgttgcc agctatttaa ggtcttgtgg agcagacgca tccttagtac
    29941 aatatttatt gagctcggat ttagcgacat acttggagat cagcaatttg attgctggaa
    30001 gcgactatgt gacttctgat attgttgtgg cggcagggac agacgaaaaa gagtataata
    30061 gtgttatagc agcaaaaaca gcagatacat tgctttcgat gatcaatatc aatgcagctt
    30121 tcgtcattac aaagcggaca gacggcttga ttgggatcag tgccagaagt accggcacga
    30181 tcaacgtcca aatcatcatg gaatccttag gtggcggagg acacttcaca aacgcagcta
    30241 ctcaactgga aaatacgaca gttgaggaaa caaaacagaa gctatttgct gcaatcaaag
    30301 aaaatatgaa tcaaatatat gataaggagt aatccaaatg aaagtaattt ttttacaaga
    30361 tgtaaaagga aaaggtaaaa aaggggacat caaagaagtt ccagcaggtt atgcacaaaa
    30421 ttatctaatc aaaaataact tggcaaaaga agcaacgaaa agcagtatca gtcagttagc
    30481 aggacaaaag aaagcacaag aaaaacacga agctgaaatc ttggaagaag ctaaaaagtt
    30541 aaaagaattc ttggaaaaag aagatactgt agtcgaattg aaggcgaaag caggggaaga
    30601 cagccgtttg tttggttcga tcccttcaaa acaaattgct gaagggttaa acaaacaata
    30661 caaaatcaaa ttagataaac gaaaaatcga attagaaaat ccgatccgtt cactaggcta
    30721 cacaaacgta cctgttaagc ttcatcatga ggtgacggct acgatcaaag ttcatgtcgt
    30781 acaagaataa caaatcttga tagcgatgtt cagctggtaa gtataaccag aaggaaaaaa
    30841 gacaaaccga aatttatctg agaaaacagc tgcagcaatg aaagcaaaag ctgcaaatcg
    30901 atttcagatt gatttcggtt tcttttttgg gaacagcaaa atagcataaa gaaaacgagt
    30961 ataataaaag agaactattt ttttattaca ctttcggtac gaatgatgac ttttctctca
    31021 ttttcttgta aaatgaagca attgaagaca aggagcgata cgtatgaatg aagtgtggca
    31081 ggatcgaatc ccaccgcaaa atattgaagc tgaacaagcg gttttaggct ctgtttttct
    31141 tgacgcagaa acgatcattg atgccatgga gtacatagag ccaaaagact tttatcgtcg
    31201 tggccatcaa attatttttg agacaatgat cgagttaaat gatcgtaatg aagcgattga
    31261 cgtggttact gtcaaagacc ggctggaaca agccaatttg ttagaagatg ccggtggttt
    31321 aagttatctc tcagacttgg cattagcagt tccgacagca gcaaatatcg tctactatgc
    31381 gaaaatcgtt gaagaaaaat cattgctgcg tacattgatc cagacagcaa caggaatcgt
    31441 tacgaaagga ttcgagcaag gagaagaagt tcaaacaatt ttagatgatg ccgaacgcag
    31501 tatcttggag gtttcggaaa aaagaaatcg aagcggcttt ttatctattg ctgaagtact
    31561 gaactccacg attgaaaata tcgatcgact agctcaaaac aatgaagaaa tcacaggtct
    31621 accaactggc tatcaaggtc tggataaaat gacagcaggt ttccagcccg aagaactaat
    31681 cattcttgct gcacgtccag cggtaggtaa aacagcgttt gcattgaata ttgctcaaaa
    31741 tgtaggaaca aaaacagatc gttctgttgc gatatttagt ttggaaatgg gggcagaatc
    31801 tcttgtaaat cggatgcttt gtgcagaagg ttcgattgag gccagccatt tacgtacagg
    31861 tcagctttcg gaagaagaat ggtcgaatct gatcgttgcg atggggagtc tttctcgagc
    31921 aaatattttt atcgatgata caccagggat caaaatctct gaaatccgtg cgaaatgtcg
    31981 gaaactagcg caagaaaaag gcaatctagg cttgatattg atcgattatt tgcagttgat
    32041 tgaaggtaac ggtaaagaga accgtcaaca agaagtatca gatatctctc gccaactgaa
    32101 aaaactggcg aaagagctga aagtacctgt cattgctctt tcacagttat ctcgtggagt
    32161 agaacagcga caagacaaac gaccagtgct aagtgatatt cgtgaatccg gatcaattga
    32221 acaagatgcg gacatcgtag ccttcttgta tcgagatgat tattatgaaa gagaaggcgg
    32281 agatgacgat gatggaaacg agccaaaaaa tgacaacgtc atcgaagtca tcatcgagaa
    32341 gaaccgaagc ggtgcacgag gaacagttga actactgttt atcaaagaat acaataagtt
    32401 ttcgtcgctt tcgccaagag aagaatttta aagaagaggt tgtgagcctt gagcaatccc
    32461 gagagctctc gtaagaagat gcaaggagta accgcaggaa cgactagagt acttaattta
    32521 aacagatctc caaagggatt gtgacaaaag tcttgtcaca gtcccttttt ccgaataaac
    32581 ggtgttcaat cagctgaccc ttggtattag ctcagcaaac gtcaaaatat gaggaactat
    32641 tttgacgttt gtttctctaa tactcaggtc aaaacgctga tcttacgacc tcttttcctt
    32701 aaacggtgtt ctcctgccaa ctcctcggtc acaagtcaca atatcatcaa acatgagaag
    32761 cagttttttg aaattgctcc ttgtgactca gagttaaacg gcaggctcac aacctctttc
    32821 ttaaacggtg ttcaaaagct tgcatctgcg gtaatacgcc caatcaaacg aaaaatatga
    32881 gaagctattt ttgtttggct gttcttatta cttgatgcag gacagctttt tcacaacctc
    32941 tgattcacgg tgttccaaaa gtagcttctt cgaaaaataa gtcgaaattt cacaaaaatt
    33001 tgagaagcaa ttttcgtaca ttccttctta tttcttgaag ctgaccactt ctgttacaac
    33061 ctctttttta ataaccattc taaaaagata aagttcgttt tttaagcgtt tttataaaat
    33121 aaaaataaaa atcattcgat tttatttgaa atatgtatct attattgata caatggttca
    33181 ggattaaata atatagaacg aggtgttcac atgtcatctg tagtagtagt aggtacgcaa
    33241 tggggcgatg aagggaaagg aaaaatcaca gactttctca gtgaaaatgc tgaagtgatt
    33301 gcacggtacc aaggtggcga caatgcaggg cacacaatta agtttaacgg tgtgacttat
    33361 aaactgcatt tgattccttc tgggattttt tataaagaca agatcagtgt gatcggaaac
    33421 ggcgttgtag tcaatcctaa atcattggtt aaagaattag cttatttaca tgaaaaaggt
    33481 gtagaaacaa gtaatttgcg tatttctgac cgcgcgcacg taatcttgcc ttatcatatc
    33541 aaattggacc aattacaaga agatgctaag ggcgaaaata agattggtac aacgattaaa
    33601 ggaatcggac ctgcctatat ggataaagca gctcgtgtag gtatccgtat tgcagactta
    33661 ttagataaag aaatttttga agaacgtctt cgtttgaatc tagatgacaa aaaccgtcaa
    33721 tttgtaaaaa tgtttgattc agaaccactt gattttgacg atatttttga agaatattat
    33781 gaatacggac aacaaatcaa acaatacgtc acagatactt ccgttatctt gaatgatgct
    33841 ttggatgcag gcaaacgcgt gttgtttgaa ggcgcacaag gtgtaatgct ggatatcgac
    33901 cagggaactt atccttttgt tacttcttct aacccagtag ccggtggggt aacaatcgga
    33961 agcggtgtag ggccttcaaa aatcaataaa gttgtcggcg tctgcaaagc ctatacgtca
    34021 cgtgtcggtg atggaccatt tccaactgaa ttatttgatg aaacaggaga acaaatccgc
    34081 gaagtaggac gagaatacgg tacgacaact ggtcgtccgc gtcgtgtagg ctggtttgat
    34141 tctgtagtta tgcgccattc taaacgagtt tcaggtatta ccaacctatc tttaaactcg
    34201 atcgatgtat taagtggatt ggaaacagta aaaatttgta cggcttatga attagatggc
    34261 gaactaatct accactatcc agcaagcttg aaagagttga actgctgcaa accaatctat
    34321 gaagaattgc caggctggtc agaagacatt acaggatgca aaacacttgc agaactgcca
    34381 gaaaacgcac gtaactatgt acgtcgtatc tcagagcttg ttggtgtacg tatctcaaca
    34441 ttttctgtcg gacctgatag aacacaaaca aacatcttag aaagcgtctg ggcgcaaatc
    34501 taaggataaa aacgacgact gaatcaggac gttcttacca gagcgagtcg aagtgtttat
    34561 ctatacgata ataataactt gaacactgtt tattcagaat aagggactgt gacaaaaacc
    34621 gtgtcacagt ccctttttcc gaa
//
LOCUS       DAFBSV010000021        32260 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.021, whole genome shotgun sequence.
ACCESSION   DAFBSV010000021 DAFBSV010000000
VERSION     DAFBSV010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32260
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.021"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            320..1981
                     /locus_tag="LLB18_000967"
     CDS             320..1981
                     /locus_tag="LLB18_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK5243983.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(2051..2398)
                     /locus_tag="LLB18_000968"
     CDS             complement(2051..2398)
                     /locus_tag="LLB18_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HBK5243984.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            2482..3423
                     /locus_tag="LLB18_000969"
     CDS             2482..3423
                     /locus_tag="LLB18_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5243985.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3424..4467
                     /locus_tag="LLB18_000970"
     CDS             3424..4467
                     /locus_tag="LLB18_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5243986.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4473..5543
                     /locus_tag="LLB18_000971"
     CDS             4473..5543
                     /locus_tag="LLB18_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5243987.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5533..6486
                     /locus_tag="LLB18_000972"
     CDS             5533..6486
                     /locus_tag="LLB18_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK5243988.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6498..7508
                     /locus_tag="LLB18_000973"
     CDS             6498..7508
                     /locus_tag="LLB18_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK5243989.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7793..8614)
                     /locus_tag="LLB18_000974"
     CDS             complement(7793..8614)
                     /locus_tag="LLB18_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBK5243990.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8711..8989)
                     /locus_tag="LLB18_000975"
     CDS             complement(8711..8989)
                     /locus_tag="LLB18_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243991.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9257..11266
                     /gene="metG"
                     /locus_tag="LLB18_000976"
     CDS             9257..11266
                     /gene="metG"
                     /locus_tag="LLB18_000976"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBK5243992.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11745..12332)
                     /locus_tag="LLB18_000977"
     CDS             complement(11745..12332)
                     /locus_tag="LLB18_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243993.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12507..13829
                     /locus_tag="LLB18_000978"
     CDS             12507..13829
                     /locus_tag="LLB18_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK5243994.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAIKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13984..14760
                     /locus_tag="LLB18_000979"
     CDS             13984..14760
                     /locus_tag="LLB18_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBK5243995.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14753..15322
                     /gene="rnmV"
                     /locus_tag="LLB18_000980"
     CDS             14753..15322
                     /gene="rnmV"
                     /locus_tag="LLB18_000980"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBK5243996.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15315..16199
                     /gene="rsmA"
                     /locus_tag="LLB18_000981"
     CDS             15315..16199
                     /gene="rsmA"
                     /locus_tag="LLB18_000981"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBK5243997.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16650..17279
                     /locus_tag="LLB18_000982"
     CDS             16650..17279
                     /locus_tag="LLB18_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5243998.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17403..18512)
                     /gene="ugpC"
                     /locus_tag="LLB18_000983"
     CDS             complement(17403..18512)
                     /gene="ugpC"
                     /locus_tag="LLB18_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBK5243999.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18721..19143
                     /gene="mgsA"
                     /locus_tag="LLB18_000984"
     CDS             18721..19143
                     /gene="mgsA"
                     /locus_tag="LLB18_000984"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBK5244000.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            19466..20002
                     /locus_tag="LLB18_000985"
     CDS             19466..20002
                     /locus_tag="LLB18_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBK5244001.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(20042..21805)
                     /locus_tag="LLB18_000986"
     CDS             complement(20042..21805)
                     /locus_tag="LLB18_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5244002.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21808..23523)
                     /locus_tag="LLB18_000987"
     CDS             complement(21808..23523)
                     /locus_tag="LLB18_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5244003.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(24302..24526)
                     /locus_tag="LLB18_000988"
     CDS             complement(24302..24526)
                     /locus_tag="LLB18_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244004.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            24717..27494
                     /locus_tag="LLB18_000989"
     CDS             24717..27494
                     /locus_tag="LLB18_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK5244005.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            27575..27994
                     /locus_tag="LLB18_000990"
     CDS             27575..27994
                     /locus_tag="LLB18_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBK5244006.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            28006..28476
                     /locus_tag="LLB18_000991"
     CDS             28006..28476
                     /locus_tag="LLB18_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5244007.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            28493..29272
                     /locus_tag="LLB18_000992"
     CDS             28493..29272
                     /locus_tag="LLB18_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK5244008.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            29259..30080
                     /locus_tag="LLB18_000993"
     CDS             29259..30080
                     /locus_tag="LLB18_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBK5244009.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            30097..31146
                     /locus_tag="LLB18_000994"
     CDS             30097..31146
                     /locus_tag="LLB18_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBK5244010.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            31159..32163
                     /locus_tag="LLB18_000995"
     CDS             31159..32163
                     /locus_tag="LLB18_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBK5244011.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
BASE COUNT        10505 a         5738 c         6579 g         9438 t
ORIGIN      
        1 ctggcttttg aacaccgttt attcagataa gggactgtga caagactttt gtcacagttt
       61 ctttttgttt attctttttt atctttgtat ggcaataata gacaatataa cgaaaattat
      121 ttaatggctt ttggaagacc atggaaaacc ttgtacaaag ctattttttc tgaaaaattc
      181 cttgaaacct cacgaaaaaa tcattatttt atgaaaaaga caaaaaaagt gttgattttt
      241 taataattat tcattaaact cttaaacaac ttcagaaaat attaattatt ctgaaaattc
      301 caataaaggg gtacgtaaaa tgaaaaagaa atttacattt ggtttggttg cggtatgcgg
      361 ccttgtactt gctggatgtt atggcggcag ttcagccaca agcagtagtt cagcaaaaag
      421 cggttcagca gatggaggag gcgtatttaa cttagtcgtg cctcaagaaa tgcctacagc
      481 tgacttatca gttgcaacag atacaatcag ttttacagca ttgaataacg tttatgaagg
      541 aatttaccgt cttgatgaag acagcaaacc acagccggca ggagctagcg agttggcaga
      601 agtcagtgaa gacggattaa cttacaaaat caaattacga gaagacgcaa aatggtcaaa
      661 tggtgatcct gttacagcag cggattacgt ttatggctgg caacgaacag tagacccagc
      721 tacagcttct gaatatgctt acctgtatgc gccagttgaa aatgcagaag acattacagc
      781 tggaaagaaa gataaatcag aactagggat caaagcagtt ggtgactatg aattagaaat
      841 caaattgacg aaacaaacac catatttcca atatctgctt gctttcccat catttttccc
      901 acaaaaacaa tccgtagtgg aagaaaatgg ggatgcctat gcatctgcaa gtgataaagc
      961 tgtttataat ggaccattca cattagaaga ttttgatgga ccaggaacag atacagaatg
     1021 gacttataag aaaaatgatc attactggga caaagataca gtaaaacttt ctgaaatcaa
     1081 agtcagtgta gtaaaagaat cttctactgc attgaactta ttcaaagatg gccaagcaga
     1141 tgacgtgatc ttgtctggtg agttagcaca gcaaaacgca aacgatccag cttatacttc
     1201 tgttaaagaa gcgcggacaa gctatatcga attcaatcaa cgtgaaaaga attcaccatt
     1261 caacaatgtg aacctaagaa aagctatttc ttattctatc gatcgtgaag ctttagtaaa
     1321 acaagtacta ggtgacggat cagttgtctc tacaggattg atcccatcag atatggtaaa
     1381 aagtccaaca acgaacgaag actttgcaaa agaagctgga aaattagttt cttatgacaa
     1441 agataaagca aaagaatatt gggaaaaagc gaaaaaagaa ttgggcgttg attctttaga
     1501 atttgatttg atggcttctg atgatgattc atcgaaaaaa gtaatcgaat atgttcaaaa
     1561 ctcaatccaa gaaaacttgg atggcgtaac agtcaaacca acacctgttc cattctctgt
     1621 acgtcttgac cgctcaactt cgggtgattt tgacgcagta ctaggcggat gggctgctga
     1681 ctatgcagac ccaagcagct ttactgattt gtttgtcaca ggtaattcat acaaccgtgg
     1741 tcgctggagc aatgcagaat atgacgaagc agttaaagca gcttcatcaa cagacgctgg
     1801 cgatgaacaa gcccgttggg atgatttcca aaaagcaatc aagatcatct ctgatgatat
     1861 gggtgtcgtt ccggtgtacc aaaaagcaga aggtcaccta gtgaatgaaa aaatcaaagg
     1921 tatcgttcac catgcggcag gcgcttcatg ggattacaaa tggacatacg ttgaagaata
     1981 atcgttaata ccgtgagcat gagaaaaaac gaggctgcgg caaatgtcgc aacctcgttc
     2041 tcatattcac ttatcctaac aaagaaaaaa gcatgaaaat agcagaaaga gcaattagta
     2101 ttccggcaat gatcagccaa aagctgtaca taccgtagct ggcagacgag agcgaggaaa
     2161 attctggttt tttctttcgg ttccttgttc gtgcaagatg gaccgatcgc tgaaaatgat
     2221 cgaagaaacc cgaagaaaag acccataaaa aaccgccgat aatcagaaac ggcaatgacc
     2281 ataagaatag atcattagat aattgaatga gtgtaaagga atggttgatg agatttttta
     2341 ttaaaataac cagaatcagt agaaaagcta ctgcgtaggg gatagatttt tttttcattt
     2401 gattgctcct ttatttttgg ttcattatct aataatgtag cgaaacatct gtcagaagtc
     2461 aaaagctagg gggaaacatt agtgaatagt tatatcaaat atgtattaaa acgtgtcttt
     2521 ttcatgatca tcacgctttg gttaattgca acaatcacct ttttcttgat gcaattgctg
     2581 ccgggcacgc catatacgaa tcaggaacgt ttgagtcctg aaacaatcga gatgctaaat
     2641 aaacaagtcg gtttggataa accagttatc gtacaatatg ggatttatct ttctaatttg
     2701 cttcaaggag attttggaat ttccttccaa tttaaaaacc agccagtcgc acatttgtta
     2761 gctggaagaa tcggaccatc cttgcagtta gggttacagg caattatctt tggaacagtc
     2821 ctagggacga ttttaggaac gatctctgcc atgaagcaaa atacatgggc agatacatct
     2881 tctacactcg tagcgatatt aggtcgttcc attccaaact ttgtatttgc tgttttatta
     2941 caatatatct ttgcaatcaa attacaagtt ttgccaatcg caaaatggga tggctttgtg
     3001 tacacaatct taccaacaat tgcgttggcc atgtcgccgc ttgctgactc tgctcggttt
     3061 atccgtacgg aaatggtgga agtactgcat agtgattatg tggaattagc aaaagcaaaa
     3121 ggattgagcc gttgggaaat cgcctttaaa catggtcttc gaaatagttt gattccattg
     3181 atgactttat taggaccgtt agctgtagca ttgatgaccg gatcactggt ggtagaaaat
     3241 atctttgcta ttcctggtat cggggaacaa ttcgttaagt caatcacaac aaatgattat
     3301 cctacgatca tggctgtaac gatcctttac tcatttatgc tgatttttgt tattttgatc
     3361 gtggatctat tgtacggtct agttgatcca agaattcgtg tttcagaagg gagccgagga
     3421 taaatggaaa tgataccaaa gcgttatgaa acagttgcag atatccctgc ggatgaattt
     3481 cttccattac aaaaaaatac cgaagaagaa cgtgaacaga ttactgcacc ttctttgaat
     3541 tttatccaag attcatggcg ccgtttaaag aaaaacaaag ctgccgttat ttcaatggtt
     3601 ttactattgg tcatcatttt gatctctgtg atcacaatct ttgtttctcc tcatgatcca
     3661 actgcccaaa acgtggctta tatcaatttg cctcctcgta ttccgggaat caatatcgat
     3721 ggattgaatg gaaaagcaat ggttggtggt gaacttgttg ataaatatgc tcaagcaaac
     3781 gtcccttcaa acgtaaattt ctttttagga acagacggtt tgggacgtga tgtattaagc
     3841 cgcttattta tgggaatgag aatctcgttg ctgatcgcat ttattgctgc attactagat
     3901 gtaacgattg gtgtagctta cgggttggtt tctggtttgt taggcggacg tgtcgataac
     3961 gtgatgcaac gttttttgga aatcttatca ggaattccaa acctcgttgt catgattttg
     4021 atgttggtcg tttttgaacc aggaattttt tcaatcgtgg ctgctatggc catcacaaac
     4081 tggataccaa tggcacgtat cgttcgtgca caaacaatga aattaaaaga tcaagaatat
     4141 gttttagctg gattgacatt aggtgaatca agaatgaaaa ttgcattcaa acatattttg
     4201 ccgaatatct ctagtgtcat tattattcaa atgatgttta gtattccatc tgctattttc
     4261 ttcgaagcct ttttaagctt tatcggttta ggtcttacgc ctccgtcagc ttcattagga
     4321 acgatgttga gcgaagggta caagacattc ctgtatctgc cttatctatt atggattccg
     4381 gcagtaactt tatcggttat catgattggc tttaacttac ttgctgatgg attgcgtgat
     4441 gcctttgatc ctaaaatgaa agagtgaaga cgatgacgaa aattttagaa gtgaaagact
     4501 tagaaatctc ttttgatacg tatgctggaa aggtacgagc gattcgcggt gtcaattttc
     4561 atttgaataa aggagaaaca ttggcgatcg ttggggaatc tggaagtgga aaatcagtga
     4621 cgaccagaag catcatgcgc ttgctgtcaa gcaacgccaa tatagatgct ggtcaaatcc
     4681 tctttaaagg taacgatatc gttggaaaat cagaaagaga gatgcaaaaa atccgtggta
     4741 aagaaatagc gatgattttc caagatccaa tgacctcttt agatccgacg atgcccattg
     4801 ggaagcaagt cgctgagtcc cttagaaagc ataataaagt ttcaaaaaaa gagggacaaa
     4861 aagctgcatt agaattgctt aaattagttg gaatacccga agctgagaaa cgtatcaaca
     4921 gttatccgca tcagttctca ggaggtcagc gtcaacggat cgtgatcgcg attgcactgg
     4981 tatgttatcc ggaaatcctg attgctgatg aacctacaac agcgcttgat gtgactattc
     5041 aagcacagat tttggagctg ctgaaagaaa ttcagacaaa aatcgataca tcaattatct
     5101 ttatcactca tgaccttggt gtagtagcga atgtcgctga tcgtgtcgct gtcatgtatg
     5161 gaggaagaat cgttgaagtt ggaacatcgg aagaaatttt ctacaacccg caacatccct
     5221 atacttgggg actgcttggt tcaatgccga cattagatag tgcgaacgat cgattgtatg
     5281 ctattcctgg ttctccaccg gatttattga acccgccaaa aggagacgca ttctatccaa
     5341 gaaatgaatt cgcgatgaaa atcgatgcag aacaagaacc accatttttt gaactatcaa
     5401 aaacacacaa ggcagcaact tggctacttg ctccgcaggc acccaaagtg acaccgccag
     5461 aagaaatcca acgtcgctgg gctatcttta aagagaaaca aaaacatact tacggtcaag
     5521 gaggaattgc tgatgccaaa taaactactt gaagttaaag gattgaaaca gtatttcaat
     5581 gtaggaaaaa agaatgaagt acatgctgta aatgacatca gctttcacat ttatgaagga
     5641 gaaacattcg gtttagttgg agaatctgga agcggaaaat ccactactgg ccgtacgatc
     5701 attcgcttga atgaacctac tgatggtgag atattattcg acggtcaaga tataacgaag
     5761 atcaaagata aaaaaggttt gacgaaattc cggcatgatg ttcagatgat ctttcaagat
     5821 ccatacgctt cgttgaatcc tcgtatgaaa gtcagagata tcattgccga aggaattgat
     5881 gttaatggac tagctaaatc atctgaagag cgtgcaaaaa aagtcgatga tctattgaga
     5941 actgttggat tgaatccaag ccacggtact cgttatcctc atgaattttc aggtgggcaa
     6001 cgccagcgta ttggtattgc acgagcattg gcagtaaaac cgcgttttat catttgtgat
     6061 gaaccaattt ctgcactaga tgtgtcgatc caagcccaag tggtcaattt gttgcaagat
     6121 ctccaaaaag aacatcaatt gacctatcta tttattgcac atgatttgtc gatggttaaa
     6181 catattagtg accgaatcgg tgtaatgcat aacggcttgt tattagagat gggaacaagt
     6241 gatgaaatct ataatcacgg tgttcatcct tatacagaaa gtttgttatc tgctattcct
     6301 ctaccagatc cagaccatga gagaaaacgc agaagaatca aatatcaacc tgaaccagat
     6361 gacggacaag tacgtcaact tcgtgaaatc gcaccagaac attttgtcta tgcaactgag
     6421 caggaagtcc catattacgc aaaaaaacta aaacgacaaa aggaatctct tctggttgct
     6481 aactaggagg gacatagatg ctaaaagctt ttaaattccg tatgtatccg acagaagaac
     6541 aaaaacagca attgattcgt acttttggat gtgctcgatt tacctataac catttgctga
     6601 aaaagcggca gaaaagttgg caacaaacag gagtagccaa tttttcgctc acacccgcta
     6661 cattaaaaaa agaataccca ttcttaaaag aagtagacag tcttgcttta gcaaatgcac
     6721 agcttaattt ggatcgggct tttcgcaatt atttcaaggg acgtgccagc ttcccaaagc
     6781 ttaaaacgaa aaaaagtatg tggcaatctt atacgaccaa caaccaaacc cgtacgatct
     6841 atctggaaaa tggctactta aagttaccaa aacaaaaaga actaatcaag ataaatcagc
     6901 atcggccagt tgaaggatcg attcgctccg ctacgatttc tgctcgatat aatgaagaat
     6961 tttatgtcgc actactttgt gatgtttcgc cagtaaaaaa agaatcttta gctaaatgga
     7021 tcgggatcgc ctatcatccg aagacattga tccaaacatc tcgacctcta gaagtaactt
     7081 taccaaaatt tcaccagaca gaagaaaagc tgcaacatgc acagcggaaa ttgaatgtga
     7141 aagtccgctc cgctcaccat agaaagatca ggttagatca ggcaagcaat tatcagaaac
     7201 aaaagagaaa agtaatggat ctttatctga aacaaaagaa ccagcgagaa gattatcttg
     7261 aacaattatc tgggaaattg gtcaaacaat atgactactt atttgtagaa tcttttccaa
     7321 aagaagaggc acatgctgat ttttctattc acgactggca taaattaata acaaaattgc
     7381 gttataagtc ccaatggtat aataaaaaat ttcttttgat caataccgac ggagcagaag
     7441 aaagcaattc cgtaagaaag agccaagtag tagaaaaaat gggcagacat tcggttatca
     7501 agggataaaa aatgaatgaa actgatagga gcgttagggt tagccttgtt aataaaaagt
     7561 cttaatgact tttgtttcta ggaatttttc ttttgaagaa aagctcacta attatgacaa
     7621 accaataaaa caatagcaga aaaagttcgt acgagctttt tctgctattg ttaatttttt
     7681 attcagaaag tttacgaata catcaaaatt ctgaaacaaa aaacgtaact cacaaagagt
     7741 tgtttttgcg ttttttcttg aatgattagg tctgaatctt ttgctcacaa ccttattcat
     7801 ggtgccccgg cttgagctga tagatttttg aaggacggcc gattcctaca ggacgttcac
     7861 cgatctcatc gaaatattgg agcatagctt tcttaaaatt ggaatgatcg atcgttttat
     7921 aatcgatccc taagaattta gcaaatactt ttcgagcttc cgtaatcgtg aaatctttac
     7981 ctaaaacttg tagaacttgc ggctcgtgtt ccattttatt gactacacgg ttgaatgctt
     8041 tcaagatgat ttgactatgg tcaaaagcca aagtatcttt gccagaagac tctccagtga
     8101 ctaaatcaag cgagatagcc acttctccgc tagataaatg gatcttgtta ctatgacgtt
     8161 ctagtgtgaa ccagcgtact tccttggcat catctccggc gattagcggt tcttctccaa
     8221 taaaggctaa gtagctgact gtgacgaccc agcctcgcgg atctcgatta ggcgtactga
     8281 atgtatgcag ttgctcaata ttttcttttg aaataaccac accagtttct tcctttgttt
     8341 ctcttaagac gctttctcca gttgactcat ccttttggac aaagccacca ggcaatgccc
     8401 atgaatttcg ataaggatgc ccttttcttt ggatcaacaa aactttcagc tgatcttctt
     8461 ctttgttata gcacatcagt acgatatcga cagtcaaaga gggcttgtca tattctggac
     8521 gttcctgttt ttgataccag ttaagaaatt cttcttcact tgctttatgt tcataatata
     8581 atttttcttc ttctttagaa gcaaaacggt tcatctgacc acctccattg acagtaaaag
     8641 tactttttac cttattgtag cagactctga aaaaaaacca aggatttact tgaaaaatct
     8701 aggttatcat ttaaatatga aaaataaatg gaagtatgag attgaataaa aagaaaagca
     8761 gataaaacgg caatacttta taccgctctt cacgaatggc aaagaagcca caaataacga
     8821 tatatacgtc aatgataaaa cgcaaaatcc aagctgctgt cataaaactg ttcaaatgcc
     8881 catggaggtt aaaataacca tacatacgaa tataaaaata gctgaatatt aaatgtgcta
     8941 atgaaagaaa agcaatacta agtgtaaaaa aaagatgttt cttctgcatg attgttccag
     9001 tcccttacta agatagatag tctttattat accacgtgtg aggggagaaa taaaaagccg
     9061 ttttttagta gatatgaaac aaaacaaaaa cccgcattta ttcaacctat tcatcctttt
     9121 aaaggataga ttgaacgtag atagaagtcg tttatccagt ctttttcatt ttgaaaaaaa
     9181 gctaacagca tgcttttttt atggtatact agcaaggaaa cgaattcgca tcatgcgata
     9241 aaggaggaag agccccgtgg cagaaaagga aactttttat atcactacgc caatctatta
     9301 tccaagcggc aaacttcata tcggcaactc gtatactacg attgcatgtg acgcaattgc
     9361 tcgttataaa cggttgatgg gctttgatgt gttttatctc actggagtgg atgaacatgg
     9421 tcaaaaaatc gaaacaaaag cagaagaact aggtgtaaaa ccgcaagaat atgtagataa
     9481 aatggcggct gatgtcaaga aattatggaa aacgcttgat atcagttatg ataaattcat
     9541 tcgcacgaca gatgattacc ataaagcagc tgttcaaaaa atatttgatc gtttattaga
     9601 acagggagat atttacttag gtgaatatga aggctggtac tctgtttctg acgaagaatt
     9661 ctttacagaa acacaacttg cagaagtgta caaagatgac gaaggtaacg tgatcggtgg
     9721 taaagcgcca agtggacacg aagtagaatt ggtaaaagaa gaatcatact tcttccgcat
     9781 gagcaaatac gcagaccgtc tattggaata ctatgaagaa catcccgaat tcatccagcc
     9841 agaatctcgt aaaaacgaaa tgatcaacaa ctttatcaaa ccaggattag aggatcttgc
     9901 agtttcacga acaactttta cttggggagt accagtcaag agtgatccga aacatgtggt
     9961 gtatgtatgg atcgatgcat tatccaatta tattactgca ctaggatatg gctccgaaga
    10021 tgaaagtcta ttcgaaaaat actggcctgc agatgttcag atggtcggta aagaaatcgt
    10081 tcgctttcat acgatctatt ggccaatcat gctgatggcc cttgatttgc ctctacctaa
    10141 aaaagtattt gggcatggct ggctattgat gaaagacgga aaaatgtcta aatcaaaagg
    10201 aaatgtcgtt tatcctgaaa tgcttgtgga acgttatggt ttagatgcac tccgttatta
    10261 tttgcttcgt gctgttccgt ttgggtcaga tggtgtcttt acgccagaag attttgtttc
    10321 ccgtgtcaat tatgatctgg caaatgatct agggaactta ttgaatcgaa cgattgctat
    10381 gatcaacaaa tattgtgatg gactcgttcc tgactatgcc tcacttgtca ctccatttga
    10441 tagtgaactg tctacgacgg ctgctaacgt tgtcggacgt taccatgatg caatggaaaa
    10501 aatggaattc aatacagcat tggctgaaat ctgggtgctg atttctcgtg caaacaaata
    10561 cattgatgaa acagaaccat gggtattagc aaaagacgaa gaaaagaaag ctgaattgaa
    10621 tagtgtcatg atccatttag ctgaatcttt gcgtatcgca gcgatattac ttcagccaat
    10681 catgacagaa acgccagaga agatcttcaa tcaactagga ttggactctg aaacaatgaa
    10741 tcttgaagga ttacactttg gcgaatttcc ttcaggaaca aaagtagttg caaaaggtac
    10801 accaatcttc ccacgtttag atatggaaga agaagttgct tttattcaag aaaaaatgtc
    10861 tgaaggtact caaacaaacg aagatacagt caaatgggat ccagaagaaa cagaacttgt
    10921 ttcaacgaaa gaaaaacaaa tcaaatttga tgtatttgaa aaagtagaac taaaagtagc
    10981 agaagtcatc aactgtcaaa aagtagaagg ggcagataag ttgctgcaat tccgactaga
    11041 tgctggagac agccaagacc gtcaaatctt gtcaggaatc gctgaatttt atcctgatcc
    11101 aagcgaattg atcgggaaaa aagtcgtcat tgtagcaaat ctgaaaccac gaaagatgcg
    11161 tggacaaatc agtcaaggaa tgatcctttc tgcagaagca ccagatggct ctttacaagt
    11221 aatcgaagca ccaaaatcca tgccaaatgg ctcagaaatc gcatagaaat tcaaaggggg
    11281 tatgacacta gttgtgtcat accccctttt tccgaaattt gagaagcaat tttcgtaaat
    11341 tccttcttat tacttgaagc caatcatata atacagaaac agagaactat ccaaaataaa
    11401 tcctagaaaa agaagtacga gcttcgctga tttttgttaa tttagaataa tactaatagg
    11461 aatcgtaaaa acagaaaaaa agcataatga taaagggtcg ggcagatttt aattgattca
    11521 tctggtactc ttttttattg tccttacatt cataaagttt gaatgcaatg actttattac
    11581 atctatattt atatctaaca gtagcgttga tgtgttaatt ataagttcta tcactttatg
    11641 ttcaattagt ttgtgctctt atatgtgtga ttgaaaatat agataaaaaa acaatcatcg
    11701 gctttgactt cgatgattgt tttctttatt ttgtaaaaat cctatcactt gattttatgg
    11761 taacctttta tttttgtctt caaacggctt ggtaagagag cagtaagcag tgcaaatggg
    11821 atcgaaaaga cataccagaa aatcgtacgt ccgataccat aatgttgata gagctttgtc
    11881 aacatcacgt gtaacaagat caaccctaaa agcaaggagc cagctataaa ccaatgatta
    11941 tcccaatgca tgacttcact aagtgccatc actccaaaag gatagaaata aaaatagatc
    12001 ccgactaagg tcatccgcca gttctttgta aatgttccga tattcaataa aaagaaaatc
    12061 gctgaaagca aaataccgat aggcggaaaa agcccaacca aaaaggaata caacatcccc
    12121 cacaagatca tcacaggacc tttgatcaat gcaacgattg cgatgaacaa agtcagcaat
    12181 attagttttt gtgataacgt tgcaacagtc attaatccaa ataaaattaa tgtgaaccaa
    12241 tgccaatggg actgctgttg ttctttacgg gaaaaatcga cccggttgga taaataatct
    12301 gctaatttcg gataagaacg cttaaaatcc ataaactgtt cctccttcgt ggaaaaggta
    12361 ggtttagtat acgaaaaata aaaaagaaat acatccgtct taagagggag tttttcactg
    12421 aaagtggaga aaaaagaatg gtaaattaaa atattctcag ttatactgaa aattatacca
    12481 aatttcaaag aagaaagagg atgggaatga aaggcaaact aaaacgagaa atcaatctgt
    12541 ttggcgcatt agctaccgtt atgggaaccg tgatcggtgc aggcgtcttc ttcaaaactg
    12601 ctgctgttac tgctagtact cagtctacaa gtttgacatt gctagcttgg cttttgggtg
    12661 gtttcttaac gatctgtgct ggattgacag tggctgaatt agctacagca atcccggaaa
    12721 ctggtggagc tataaaatat attgaagctg cgtatggaaa attgcccagc tttttattag
    12781 gatgggcgca aagcttgatt tactttcctg ctaatattgc tgcattatcg attatctttg
    12841 cgacacaatt gacgaactta ttacaattat ctaccgatta tcttttgttg attgcagtga
    12901 tcaccgctgt ttctgtgaca gggttgaatt tgttagggac aaaagtcggt gcttctgtac
    12961 aatcagtgac gttgattgtt aaattaatac caattgctgt gattgtcata tggggattat
    13021 tgaccccagg acaaggaact gtccagttat ttccaatcga agctggaaaa gatgttactt
    13081 ttgtcgaagg attgagcagt gcgttgttag caacgttgtt tgcttatgac ggctggttag
    13141 gtgtcggtgc aatggcaggg gaaatgaaac ggccggaaaa agatttgcct aaagcaatta
    13201 ttcttggttt gagttttgta acagtcgttt atctattgat caattttgtt tttttgaaaa
    13261 ctttgccgat tgatcatctt gccggtaatt tgaatgcagc ttctgaagca tcagacgtca
    13321 tttttggagg aatcggtgga aagctggtca ctattgggat cttgatctcg gtatacggtg
    13381 cattgaacgg ttatacacta actgggatcc gcgtgcctta tgcgatggct ttagaagacg
    13441 agctaccttt cagtaaacag ctgacaaagc tttcaaagaa gtttacggtt ccttatgttc
    13501 ctgcggtttt ccagttagca gtagcttgta ttatgatgag ccttggttct ttcgactttt
    13561 taacagacat gttgattttt gtgatgtggc tattcagttt actgattttt atcggtgtct
    13621 ttattttaag aaaaaaagcg ccggaattgc cacgtccata taaagtacca ctttatccaa
    13681 tcgttccgat tattgcgatt ctcggtgcta ttttcatttt aggtatgacg atgatgacgc
    13741 aaacgaaatt agcattgatc ggtataggtg ttaccttgat aggtatccca gtctattatc
    13801 aaaaaaagaa aaaacgctca gaagagtaaa atatttcaac aacagacaga aaaagtacga
    13861 actaggtcct ctagatcttc gtgctttttc tatttcaata aaacaagttc ttctattttg
    13921 atttttgcta cttctgcaag tagtgcttat gtgctaaagt aagaatgaaa aggagagata
    13981 aacatgatat ttgattctca tacccattta aatgctgaac agttcaatga agatattcca
    14041 gaaacgattc agcgagcaca agaaatgggg gtaacgaaaa tggcggtcgt gggcttcgat
    14101 acgccaacga ttgaaaagtc tttgcaatta agccatgact atccaaatat atacagtatt
    14161 atcggctggc atccgacaga ggctggcagt tatacgaaag aaatcgaaaa taaattacaa
    14221 gaacaattga ctttaccaaa ggttgtagca ttaggggaaa ttggcttgga ttatcattgg
    14281 atggaagacc cgaaagaagt ccaagataaa gtatttcgca gacagattgc tatcgcaaaa
    14341 gaaatgaacc taccaatcag tattcatact agagaagcac ttgaagacac gtatcaaatc
    14401 ctaaaagaag aagatgttcg agatatcggt ggaatcatgc atagtttcag tggtgattat
    14461 gaatgggcaa aacgatttct tgacttaggg atgcatattt catttagcgg tgtcgtcact
    14521 ttcaaaaaag cattagacgt ccaagaggct gcagcaaatg taccaatcga acgattactt
    14581 gtggaaacag atgcccctta tctggcacca gttcctttta gaggaaagcg aaatgaacca
    14641 ggctatactc gttatacagt agaaaagatt gctgaacttc ggaatcttcc gacagaagaa
    14701 gtggctgccc aaacatggac aaatgcgcac cgattatttg gtctaagcga acatggataa
    14761 gatgaagatc caagagatta tagtcgttga aggaaaagac gatacaagaa ggctgcggga
    14821 agtagttgat gcagatacga tagaaacaat agggtctgca atcaatgaag agatcctgat
    14881 gcaaattgaa catgcccaag agactcgtgg agtgatcgtt tttaccgatc ctgatttttc
    14941 aggagaaaaa ataagaaaaa tcattatgga agctgttcct caggcaaaac atgctttttt
    15001 gccgcgcaca caagctaaac caaagaaaaa gggaagcctt ggtgtcgagc atgcaagtga
    15061 tgctgctatt ttagaagcat tgaaaaaggt cgtgacgcca gacatttccc aaacggctgt
    15121 ttctgaaatc actagacaag accttttaga ctatggttta atagctgggg cacaagcaaa
    15181 agaaaaacga gaaaaactag gtgacgagtt gcgcatcggt tacacgaacg gcaaacaatt
    15241 ggaaaaacgt ttgaagatgt ttcgtattac gccgaaagaa ctcgcccaag caatgaaaat
    15301 agtggaggaa caacatgagt gaatatcgtg aaattgcgac accctctaga acaaaagaga
    15361 ttttattgaa acatggtttt tcatttaaaa aaagtttagg acaaaatttt ctgactgaac
    15421 caaatatttt aaggaaaatc gtagaaactg cgcaaataga tgaacatacg aacgtgatcg
    15481 aagttggacc aggaatcggt gcattgacgg aacaattagc caagcatgca aaacaagtcg
    15541 tagcatttga gatcgatgat cgtttgatcc ctgtattggc tgatacgatg caaccctatg
    15601 acaatgtgac tattgtacat caagatattt taaagaccga tttgtcaaca gctgttagag
    15661 aaacatttca tgaggagctt ccgttaaaag tcgtagcgaa tttaccttac tatattacga
    15721 caccgatcat gatgcatttt cttgaatcag atttggttgt ggatgaacta gtcgtcatga
    15781 tgcaaaaaga agtagctgat cgtatctctg ctgaaccagg aacgaaagct tatggttcat
    15841 tatcgattgc tgttcaatat tatatggaag ccagtttagc attcatcgta ccaaaaacag
    15901 tatttgtccc tcagccaaat gtagattcag cgattttgaa actgacaaga agagatatac
    15961 cggcagtcga agtgacagac gaaaaagcat ttttccgatt gacaaaagcg gcatttcagc
    16021 aaagaagaaa aacgctttgg aataacttgc agcattcgta tggcaaagat gaccagacaa
    16081 aagcatggtt agcaaaaagc ttggaaacag ctggaatcga tccaaaacgt cgtggggaga
    16141 ctttgtcatt acaagaattc gccgcattaa gcaatgcgat gtcagaaaat atgcagtaaa
    16201 aaaagaggtt gtgacagaag ttgtgaaaaa gctgtcctgc atcaagtaat aagaacagcc
    16261 aaacaaaaat agttcctcat gtttttcgtt tgtttgggct tattaccgca gatgcaagct
    16321 tttgaacacc gtttaagaaa gaggttgtgg gcctgccgtt taactctaag tcacaaggaa
    16381 caatttcaaa aaacagcttc tcatgttttt gagttagttg gtcttattac ttgatgcaag
    16441 cttttgacca ctattatgcc gaacaaggag atgtgacaca aattttgtca catctcctat
    16501 ttttgtttct tgatcaaaaa attcttatac ttgatactca cactcatttt gtatggattt
    16561 agaaaagaat atgtgtcttg acagttatta gtaagtgagt tatactaagt cgacatttat
    16621 gtgtcaagac atattaggag agagaaaaaa tgagaaaaaa ttcagttcga aaactaacga
    16681 tttctgcttt attgattggg atgggggtca ttatcccaat ggtcatgcct aaaatcatga
    16741 ttccaccagc ttcctttact ttggcgtctc atgtgccatt atttattgcg atgtttttta
    16801 caccaggagt tgcagtggct gttgcgctag gtacgacatt tggtttcttt ttaacaacgc
    16861 cggttatcat cgcattgcga gcattgtcac atcttgtgtt tgcgttgatt ggggcttggt
    16921 acttgcaaaa gcatccgagt atcgttttaa aaaatggaca gtttactttt gctaattggc
    16981 gtttccaagg gttcaatttt gtgatcggtg tgattcattc tttagcagaa atgctagtag
    17041 tcagcatctt ttactttatt ggtaatatgc ctgaaacata ttattctcaa ggatattttt
    17101 atacagtatt catcttgatg gggattggtg ggcttatcca cagtttagtt gattataata
    17161 ttgcttattt tatagcagga acactcagca aatattttga tatccccgta tttacggcag
    17221 caaaaaaaga aaatcggaaa gagtcgattc aagggtacgc gaagaaaacg acatattaga
    17281 catgatctct caaaaaaaaa actctcatct agtaatggat aataaatcct ctaagatgag
    17341 agttttttgt cctaaaaaga gctgcaccaa catcttctgg cacagctcta acagggggca
    17401 atttatggaa gtttgatgac ttgttctgtt tctttatcaa agaagtggcc tttgctgatg
    17461 ttgaaggcaa ggtcgactat ttcgcctggt ttatggaaat ctcttgcatc tacttttgag
    17521 atgaactcag tagaaccagt ttttgtgtaa agcatcgttt cagctccaag taattcggaa
    17581 acgacaactt ctgatttcac tacggcttca ggtgaagctt caagggctac ttgttcactg
    17641 tggatgtctt ctggacgaat accgaagata acttcttttc cttcataacc tttttcaact
    17701 aatactttgt tttttccttc aggaatacga agcttaagcc catgtccatc tgtgataaca
    17761 ccatttttca atgtcacatt aaagaagttc atggcaggag atccaataaa gccggcaacg
    17821 aacatattga cgggtgtatc ataaacttct ttcggtgtac cgatttgttg gataaatccg
    17881 tctttcatga taacgattcg gtcagccata gtcattgctt ctgtctgatc gtgagtaaca
    17941 tagatggtcg ttgtttcaag acgctggtga agtttggcaa tctcagcacg catggctaca
    18001 cgtaatttag catctaaatt tgataatggc tcatccatta agaagacttt tgcatcccga
    18061 acgattgccc gtcccaatgc cacacgttgg cgttgtccac cagataaagc agctggtttt
    18121 cgtttcaagt attctgtcag acctaagatc tctgctgcat tgtccacacg ttttttgatg
    18181 tctgctttat catatttacg taatttcaag ccaaaagcca tattatcaaa aacagtcata
    18241 tgaggataca atgcgtagtt ttggaaaacc atggcaatat cacggtcttt aggtgccacg
    18301 tcattcatga cttttccgcc gatatttagt tctccttcag agatatcttc cagtcccgcg
    18361 atcattcgca aagtagttga ctttccacaa ccggaaggac caacaaaaac gataaattca
    18421 cggtctttga ttgatagatt aaaatcagtt acagaataat tttctgcatt gtcatatttt
    18481 ttatatacgt ttttcagagc catttctacc ataatacgtt ccacactttc ttttttagtt
    18541 ttattaacta tttaaagtat aaatgaaagc gttaactaac ttcaatgtca tgttgaacaa
    18601 gaattttttc ttttttttgt caatgtgcta gttttaagct ttaataaata tccataagaa
    18661 ataaaaactg atacactgga gtaaataagt atgttaacaa tatcaaaagg agtgtctctt
    18721 atgaaaatcg ctttgatcgc tcatgaccga aaaaaaccta tgatggtgaa attagcaaca
    18781 gcgtataaaa caatattgga aaaacatgaa ctttttgcta ccgggacgac tgggcagagg
    18841 atcacggaag caaccggctt gccgatccat cggtttaaat ccggaccgtt aggcggggat
    18901 cagcaaattg gagccatgat ttcggaggat cagttagatt tggtgatttt tcttcgagac
    18961 ccgctggctg cacagcccca tgaaccagat gtaacagcac ttatccgttt atctgatgtc
    19021 tatgagattc cgttagctac gaatatcgga acagctgagg tgctactaag aggactggaa
    19081 gccggcttcc tagattttcg aagaatcgtc catgaaatag acaagcatcc actttcattt
    19141 tgatggataa gcgtatggaa aaataacgtt taatgttcgc ctatatgtag ctataaaagc
    19201 taaacaaact gataatatgc gatataatac gaacgtattg gataatataa acaataatat
    19261 tagtttttcg tatttgcagt aaatgtgaaa atatgctata gtttctgtgg gaaaagatcc
    19321 caaaaataat acagagtaga aaataaagcg ttaagtgcta agaggatggg atgttgcctc
    19381 ttggacgaag gacgtaatgt tcgcggtttt attttcgcat tcgctgcatg atacgatgta
    19441 gcagctctta aaggagatgc taaaaatgaa gaaacaccgg ttagacgcac gtatgattgc
    19501 tattatgggc ttattgattg cattgatggt cactttgtcc cgactggtag caatcgagac
    19561 cccatttatt aaaatcagtg tcacatttat tccacaagtg atcatgggca ttctttttgg
    19621 tcctttttgg tcagggatag gcgcagtttt agctgattta gtaggaatgg ccctcttctc
    19681 gaaatctgca ttctttattg gatttacatt gaatgcattt attgaaggag caatctacgg
    19741 attctttttc tatcgaaaag agatcacttg gaaaaatgcc attctggcta cgcttagtgt
    19801 cacgctgatc atcaacttat ttttgacacc attatggctt gcgttgatgt accatgtgcc
    19861 attgttcagc tgggtcgttt gggcgccccg cctgttaaaa acagtaatat ggttaccgat
    19921 tcaatcaatt gccatttatt acgtaggacg tagtattcct tacaaaaaaa ttttaagaag
    19981 tttagcgatc cacgctaaat aaaaaacaag cagtcttccc atcccagaag actgcttgtt
    20041 tttattgtgc tgtgaattgt gcttgataga gccgtcggta ataaccatct ttttgaagca
    20101 gctcatcatg ggtgcccatt tcgacaatag ctccctgatc catcactaat atctggtccg
    20161 catttttgat tgtggacagg cgatgggcaa tcacaaaact ggtttttcct tccatcattg
    20221 ctaagaaggc ttgttggatt tttttctctg tcaatgtatc gactgagctg gtagcttcat
    20281 ctaagatcaa cataggggga ttactgatca tcgttcgagc aatcgtcaac agttggcgtt
    20341 gtccatctga tatctttaac ccttgaccgc caatcttagt atctaatttt tccggcaaac
    20401 gttctacaaa ttcatacata taagaggctt ttagggcatc attgatttct gcgtcacttg
    20461 cttccggatt cccaaaacga agattttctc gcaatgtact gtcaaatagc caagtatctt
    20521 gtaacaccat tccaaaactt ttacgtaatg tatcacgttg gatagagcgg atgtcatggt
    20581 catcgactgt aattgttcct tttgttgtgt cataaaaacg catcagcaaa ttaacaagtg
    20641 tggattttcc ggcccctgtt tttcctacta tagcaatggt ttgacctgga taagcagtaa
    20701 aattgaaatc ttcgatcaaa cgctgcttgg ggtcataaga aaaagaaaca tgatcaaaag
    20761 agacttttcc tttgatattt ttgggttcca aggcataggc atctggcaaa tcaggctttt
    20821 cttctggctg atcgatcaaa tcaaatgctc gttctagacc agaaaaagcg gtttgcagtt
    20881 gtgtcgtgat tccagaaagt tcgataaatg gtttagaaaa ctgacttgag tagatcgtaa
    20941 agctggaaat cacaccaaca gtgattgacg aaccactctt caatgccaat aggccgccaa
    21001 ctaaaccaat cgataaataa gcaaggtgat ctacaaaacg agaagacggg tttgtcaagg
    21061 aagaagaaaa ttgtgcccgt tgtccttttt catatagatc agcatttagc agttcaaatt
    21121 gctgttgact agcttcttct tgctgaaaag ctttcacgat tttctggtta ccgattcgtt
    21181 cggtcacaaa gcccgagata tccccaataa tcctttgctg tctatcgaaa tttgtttgtg
    21241 aagcacgagc aacgatccaa ctcacaagga aaataattgg tgtagaacaa agaacgacca
    21301 atgtcagaag tggacttaga cgcatcataa aaataaacga aagaatgatg attgccactc
    21361 cagaaaataa ttgattgaag gccgcagaaa ttgcaatgga aatattgtcc atatcatttg
    21421 taaatcgact gacgatattt ccgtgggagt tttgatcata ataacgaagt ggcaatcgat
    21481 tcagatgagc aaatgcatct tttcttaatt ttgcaacgga taagtaagct aaccgattgc
    21541 ttaacacttg gatgagccat tgactgacta cgttgattaa aacgatacca ccgaatagaa
    21601 taagtaaatg gaacagtcga ttgaagcgga cctgtccttc tccaatcatt tgatcgatac
    21661 tttgaccaat ttgtaacgtc atcacaactg ttgcaatccc attgatgatt cctagtatca
    21721 cagctagcca aatgtctttt gcataggcag taaggtaagg aatgaatcgg cggagcgtct
    21781 gcaaggataa tttttttact ttcataacta ttcttcctcc tgtgatgcga cgatttcctg
    21841 atattctgct gattgagcaa gtaattcttc atgggtaccc tgagcagcaa tcttaccttg
    21901 atccatcact aagatatgat gtgcttcttg aatagagcgg acacgttggg agataataat
    21961 cactgtactg ccaagataag tctgtagcgc cttacgcaaa tccaagtctg tttgataatc
    22021 caacgcactt aaagagtcat ctaaaatcag taatgctggc ttggcaatca aagctcttgc
    22081 aatcgtcagt cgctgttttt gtccgccaga gaaatttttc ccattttcca tgacttttgt
    22141 atctaaacca tttggaagct gacggacaaa ttcttctgcc tgagcgattt tcagagcttc
    22201 ccaacattct ttttctgtgg cgtctttctt accccattga aggttttcac gaatagtccc
    22261 ggtaaatagt acagaagttt ggggaacaag agcaatttgc tgacggagat gatccagctg
    22321 ccaagaacga acatccattc cgtccattat aactgtaccg gaactgacat catagaaacg
    22381 cggaatcaat tgtgtcaaag tcgttttccc gcttccggtt ggaccaatga ttccaaggac
    22441 tgtatttcgc ttcagctgaa atgtaatatt ttggagagaa agaccagaat caggagtata
    22501 acggaagtca acatggtcaa aagcgataat tgcttcagaa gaaaaatcgg gagtagtact
    22561 gacctcagct tcaagaatcg aattttctgt gtctagcacc tctttcaccc gatttcctga
    22621 agcttcggca cgtgtgaaga tcacgacgag gtttgaaaca acgatcagtg ccaaaagcat
    22681 ttgattcata taattgatca aagcaagaac ttgtccttgt tgcaagctac caatatttac
    22741 tttgatcccg ccaactgtca gcaaacagat gatcccgaca ttcatgatca aggttgtagc
    22801 aggtgataat agggcagaga tattggaaac acgtaaataa ttgttcgcta gatcatttgt
    22861 gcttttatcg aacttctctg tttctttttt tgtctgcgca aatgcgcgga tgacacgaac
    22921 accgctaaga ttctgactaa cgtgttcatt gagctgatct agtttttctt gcactttttg
    22981 gtagagagga acggtttttt tgatgataaa aaataaaatg attgagaaaa taggcaataa
    23041 tgctaagaaa aacagaccta cttcccagtc gatcacaaaa gccatgacca ctgacccgat
    23101 acttaaaaac ggtgctctga tcaataaacg aatgaccatt gctaaagcta gctgaagctg
    23161 attgatgtcg tttgtcattc gggtgatcaa ggtatctgtt ccaaaatgat tcaactcgtt
    23221 gtgagagaaa gtattgattt ttttgattag ctgattacgt aactctgtac caaatccttg
    23281 tgaagctact gaagcatagt attggcaaat gatagcacaa atcagaccaa tcacagacat
    23341 agcgaccatc cataagccca tttcaatgat ttttcctcgg tcattcattt ttagtccatt
    23401 atcgatcaag gaagccatca ttaaaggcag gacaagttcg aagacagctt caagaaattt
    23461 gaagaacggg cccaaaatga tttgcttacg atagtctttt gcataacgta ataactgaat
    23521 catatgattc ctcctattat ttatttgtcc acaattgaaa aaacaagtac taccacattg
    23581 tagcttagga aatttagaat gaaaagagaa caagcctttt cataaatgaa agttttatta
    23641 tgaagaagct ttagaaattg aatagactat tttttttaaa aaaaagaaaa tgagaaaaca
    23701 tgccagtctc ttcattcata ggaacgtcta ttttacttaa tttttctata aatgaattct
    23761 gcataaaaaa tatatcaagt aaatgtttat agatgaaact ctatttactt cttttttaat
    23821 ttgttcttgc aatctttttt gctacgtaat ttttgtaaaa aagtgggttg agagaaatct
    23881 aattgatttt caaagaagga gtatgaaaat gagaaaaata tttattcgtt tattgtgggt
    23941 actatcttag aggaataaat aatagtggag aaaactatgg tttggcgcag attctatcag
    24001 gtttgatgga acgaagacaa cctcccgaca tcaagtcaaa agctacttga gattttgatc
    24061 tgaaaataaa aaaagaaaac aaggtaggaa catcaatgtt tctaccttgt tttcgtaatc
    24121 aatgggaaaa aactaagagt ggtgtacgta atcaataaaa aggatggtga caacagtacc
    24181 tctttactct ctgaaagcat cataactcgt ttttcctcat tatgccaata aattgttgtt
    24241 ataccacata taaggatttg taatagctaa aaacagacag gaaagttgaa atctgtgaat
    24301 cttattttgt atggaaggat ttatagaacg caaaaatcaa gataaagatg aataaaaatc
    24361 ctgtttcggc tatatattgc gtatctacgc caataaaacg agtttgttct gtcatagcca
    24421 tataaagcaa aggcaaaaat acaactacag cgagataaga tccgatgatt tctcgaaaag
    24481 ttttccagga agtatgtttc ctgtttttat atttatccga tttcattgaa tagtcatagc
    24541 ctccttattc tttcatatgt tgaaattcca gtataaaaac tggaaggaac tgtacgtttt
    24601 ttagaataaa aattataagg gataagtagg ctgctgtcta taataagata tatttttcaa
    24661 ttctttatta aagattttat tgacaaaatg aatccgtttt ctatgatgga ggaggggtga
    24721 ataagttgtt gaagaaggaa attttatgtt acttagagaa ccagacagcc tttttcgatt
    24781 tagaacatat gaacgaggtc tttacagcac aaaggttagc tgatcatttt ggggtaaaaa
    24841 gaaacacagt cagtcattat ttgaaccagt taaatgatga gcaactacta gtcaaaatca
    24901 attctcgacc agtgatttat ttccacaaag aagcttttga aaaacaattt tttaagttac
    24961 gcacgaattt ttatttttct atcgatgatc tcaaagagga acagcctttt ttcgcgcaac
    25021 caaaagactt attctctttt atgatcggat acgacgccag tttgaaagaa agtatcgaac
    25081 aaatcaaaac agctctttac tatccagatg gcggattacc acttttgatt acaggcgaaa
    25141 gtggcacagg taaaagttat ttagttaatt tggtctatca gtattgtctg cttcatgatc
    25201 tgctagaaga ttctgcacca ttcatcactt ttaattgtgc acaatatgca gataatcctg
    25261 aacttttgac tagcaatttg tttggacatg ttaagggagc gtacactggt gcagaagaaa
    25321 ataaaaaagg ggcttttgaa gcagcagatg gtgggatctt gtttttagac gaggtacatc
    25381 gcttaacacc agaaggtcag gaaaaactgt tcacctatct tgatcaaggt gtgatttatc
    25441 gtatgggaga acctaatttg tcacgccgga tcaaaacacg tctctttttt gctacgactg
    25501 aagagattac tagtcatttc ttaacaactt tcattcgaag aatacctatc cgaatcgaac
    25561 tacctgcact taatcagcgt agtcgtaatg aacggctaga actgatttac tctttttttc
    25621 tcgaagaaca aagaaaaatg gggagccctt tgtcagtcag tggaccagct ttgtcacttt
    25681 taacaagtca gaaattatcc ggaaacatag gagagctgaa aaatatcgtc aaagtttcag
    25741 cagcaaaagc atatgctgaa cagcgtgaac agcctgaaat ccatgtcacg atccatcatt
    25801 tgcaaaaaga actacttgcg cagcctatta ctaaaaatac agcacagcaa ggaatctata
    25861 ttacgcaaga ccagacctta gagcaattaa tggagaagca acagcccgaa cagcagcgaa
    25921 tcgttaaaag ttttgagcaa atcctaattg atttcaagaa aaataactgt ctgctatatt
    25981 cttgcgaagg aaaattaaag caagaagtga ttcaattatt tgattttttg ctgtttgaga
    26041 ccagtagaca agaaaaacac gagctgctgg tttattggac acaatctatc cgagagacct
    26101 ttcgacaaat ggaaactgcc tatcaaatca aattcgatgg aaacagtgtc tatgccttga
    26161 gttactatct ctatcagcga agcactatca aatggttacc ggaagaacat gatattatcc
    26221 aactaatcaa agaattagaa caacaagttt ctcagtctta tccatctagt tatcactatg
    26281 tccaacgaat tctggaatta agtaagatca aattagatat tgaagacaca agtatggatc
    26341 ggattttact gacgatctat ctaaaaaaag cgaaatggtc aaaagaaaaa cgactgccaa
    26401 aagcgatgat tgctgctcac ggttatgcaa ctgctagcag tatggcaaat gtagtaaatc
    26461 gtttattaca agaggatcta tttgaatcat ttgatatgcc actagatgtc acaccacagc
    26521 agattgcttc agaaatcctt gattattgcg aaaacagcga tgtttcaaat ggattgatca
    26581 tattagtaga catgggatct ctgaaagaaa tccatcagtt ttttaaaaaa cagttatccg
    26641 taccgctttt gattttgaat aatgtgacga cacctttagc aatcacagta ggggaatgcc
    26701 tgcaaaaaaa tgtatcatta gaagagatag cagaagagac tgttcgacag atccagccag
    26761 aatggcgact gctctatcca gaggaaaaca aacccaaagc actcattact acttgcttca
    26821 ctggaatcgg tacggcggtc cacttaagtg aactgctaga aaaaagctta cctacggctt
    26881 gtcagttgaa aatcatccca tatgaatatc agcaattaaa agataagaaa aacagtgacc
    26941 cattattttc catatacgaa gtcgtaggaa tgattggcac cacagatcct gatatcacca
    27001 atatcgacta tctttcatta gaagacctca tctcggggga aaagatgtct gtactagctg
    27061 aatggttgga cactactatg aatgcttcag agaaggaaat attcaatcag cgcatcattc
    27121 gtaatttttc attggaaaaa gtactggatt ccgtgactat tctagataca gagaaggtga
    27181 tgggagaaat cgatcatttt atgagagaat tagaggtgca gttgaatcga agcatcagca
    27241 atcccaaaaa attagcgttg tatgtccatg tgagctgtct cattgaacga ttgatccgac
    27301 aaatgccaat cgaaacctat caaggattag agaaatggaa gcagtgtcaa aaagaagggt
    27361 tatctgctat taaatctgcg tttagtgtca ttgaagagca ttatagtgtc atgatcccca
    27421 attctgagat tgcctatatc tatgatattt tgagtgaaga tacagagttt ctctcgatag
    27481 aagaagaatt ttgaacataa gcaagttgtt gccactaatt ttggcatgca acttgctttt
    27541 ttagtatgtg taagtgaaaa gaggagatga aaaagtggat agagaaatta tcttagcttc
    27601 ccatggaaaa tttgcttcag ggatattaga ttcattagag ctgatctatg ggaaaaatca
    27661 ttctattact gtattcgatt gctatactga tgagaatttt gatttagcgg aaacagtaag
    27721 gcagcttttt atgaggtaca aagataaaga aatcattgtt ctgacggatc tttttggcgg
    27781 aagtgtcaac aacgaattct tacaatatat caatcgggat catgtctatc tcgttgccgg
    27841 attgaatttg ccactattga ttgagctagt atctcggttg gacgctgaag tagagacaac
    27901 tgttttgatc cagcaggtgc taactgattc aaaaaaaatg atccagtttt gtaacgagcg
    27961 gctcaatcag aaaatagaag aagacgaatt ttaggaggaa gaaaaatgat tgtattgaca
    28021 agagtcgacc atcggttatt acacggacaa gtagcttttt catggacaca aacaataggc
    28081 gcagactgta ttttgattgc taatgatgat gtacctacga atgagatacg aaagacaacg
    28141 atcaaattag ccaagccaca aggagtcaaa ctagtgatca aatcaattga tgactcgatt
    28201 gccgcgttga aaagcggggt gacagataaa tataagttat tcatcgtagt ggaatcgatc
    28261 gaggatgcat ataagctggc agaagcgtat ccagaaatca aaaccatcaa cttaggaggg
    28321 atcaaggcaa aacctggtac tcgcagcatc ggaaaagcgg taaatatttt accagaagag
    28381 gaggaacgct tgaaacgatt aattgacaaa caaatagaag tagaaatccg tcaagtacca
    28441 gcagataaaa aagtggatgt aagagaagtt ttgtaagaaa ggaagaacct caatgattgt
    28501 acaagcagtc ttattaggaa ttgttgcatt tgtcgcacaa tcagaatatg cactagggac
    28561 atcgttgctt tctcgtccga ttgtgacggg gctgtttaca ggaatcgtgt taggtgatgt
    28621 aaaaactggg atcattatgg gcgcaacttt agagttagca tttatcggat cgttctcagt
    28681 aggtgcttcg attccacctg atgttgtgac cggtgggatt ttagggacgg cttttgctat
    28741 tacagctgga gccggtacag aaaccgcgct tttactaggt ttgccgattg ctacgttgac
    28801 attgatattg aaaaatattt acttagggct tttgattcca attatgaacc ataaagcaga
    28861 caattatgca gaagaaggaa attataaagg agtcgagcat atgcacttgc ttgccggtat
    28921 cggtctttcc ttgatgcttg gtgttgtggt aatggtttct tatatggtgg gaagcaatac
    28981 gatcggaaat ctattaaata tgattcctga cttcgttcaa aaggggttgt cagtagctac
    29041 agggttgatt ccagctcttg gttttgcgat gcttgctcgt ttgctgatca acaaacaagt
    29101 tgcaccatat tttttcttag gttttgctat agcttcttac ttagagattc ctgtgaccgg
    29161 agtagctatt tttggtgcga ttttagcagt tgtggtagtc aatattatga atgtccgtca
    29221 actaccactt caaacaactg caggggaggt agaagaagat gaagaattct gagatcaaaa
    29281 acagcaaaat aacgaaaaaa gagctaaatc acgtattttg gcgttctttt caaatggagt
    29341 tttcttggaa ttatgaacgt cagatgaata tggcttatgt ttatgcaatg attccgattt
    29401 tgaaaaagtt atatcagtcg aaagaagaaa tggcagcagc tttgaaacgg catctagagt
    29461 tttttaacac gaccccacat atcgttacac tgattttagg aatcacggct gcaatggagg
    29521 aagaaaataa ggatgatcct gaatttgatg tgactgcgat cgatagtatc aaaacatctt
    29581 tgatgggacc tcttgcaggg ttaggagatt ctttcttttg gggaactttg cgattgattg
    29641 ccacaggtgt gggtacctct ttagccatgc aaggaaatat tttaggccct atcttgttca
    29701 ttttgatttt caatattccg cacattctgt ttcgctatct agcaacaggt tggggatatc
    29761 gcttaggaac gggttttttg aaaaagatcc aggcaaacgg tatgatggaa agtttgacat
    29821 taggcgcgtc tattattgga ctgatggtcg ttggagcaat gactgccacg atgatcacca
    29881 tcaatattcc tttaaaaatc ggttcaggag aaaatgctgt gactgttcaa agtatttttg
    29941 atgatatcgt tccaaatatc ttatgtcttg gagcatttgg catagtgttt tatctattga
    30001 agaaagaagt gaaaccatta acgatcttga tcggactagc tttctttgga atttttggtt
    30061 cgtggatagg gattttttaa aaaaggagca gagaaaatgt ttacgatgca agattatatc
    30121 tatgaagaaa aggaagtact aagtacgatc ttgaaaaaga atgatttttc gacaagagaa
    30181 catatgaaaa aaacagtgaa tttactgatc ttagcaacgg gttcatctta taacgcttgt
    30241 ttagcagcga agccagcatt ggaatcttat ggtgatctta ctgtcgatat tcaagaacct
    30301 ttttattttt tcaattatgg aaaactttct ccttcaatcg atactgtgat tgctgtgtca
    30361 caaagcggga aaagtgcttc tactgttgaa gcagtaaaaa tgatacaaaa acaagggtta
    30421 cctgttgttg ctatcacaaa tgacgtgcaa agtccacttg ctttagaagc tgcacaaatt
    30481 attgatttag gtgccggggt agaatcagta ggcttcgtta caaaaggcta ttctgcgact
    30541 gttttacagt tactactctt agggatagga attggaataa gtaaaaataa aatcagcaaa
    30601 aaaatagaac aagactacat gcaacagttg cgcaaaataa tcaaccattt accagcgatt
    30661 attcaaaaaa cggaagaatt ttttgatgga tatcaaagtt tatttcgttt agcacagcgt
    30721 ttcgtcacca ttggatatgg tccaaactgg ggaacagcta aagaagcaga gacgaaattg
    30781 actgaaacaa tccgcgttcc gtcacaagga tttgagttag aagcttatat gcacggccca
    30841 tacctggagg cagatgcttc gcatttgcta ttctttattg aaggggaaag tgtaaataag
    30901 gaacgttcgc aaaagttgca aagatatatg agtcggtacg ttggagagac tctcaccatt
    30961 accacaaaaa aagcaagaaa cgagaaaaca cttggattag caatagaatg tgatgaatat
    31021 ctgtctgtat tagcgcttgt cgttccgttt caactattcg cttataaaac cgcagtagct
    31081 aaaggtattg acttgaacaa aaagattttt gaagactttg atacagtctt gaaaagtaaa
    31141 ttataagagg tggaaatcat gctgaaattc aatgaagaag aacaaatcaa agcaataaaa
    31201 ggcgcactag ctttacgtcc gcaagtagaa gaaatcatcg ataaacttta tgcggaaaaa
    31261 tttgacgctg tctattatct aggaatcggt ggaacgtatg cttcctcgat gcaagctgtc
    31321 acttatatga atgggaaaag caacttgcct gtctttgtac agcatgctgc agaatattac
    31381 actactggaa acaaaagatt aacaaaagat tctatcgtta ttttgtcctc tgttaccggt
    31441 acaactcaag aagtagtgaa agcagtagaa caaatcaaga aagtaggagc gacactgatt
    31501 ggatttatcg ataaagcgaa cagtaagttg tctcagctat gcgattttgt ggtcacttat
    31561 ccagctcctg gaacagaaca aatcaaattt tttatggcag cagatcgatt gatgtatttg
    31621 aatggagaat tcgaagctta ttcagaatac tatgaacagc tcgaacgtta tttaccaaca
    31681 gggttagtgg aagcagagaa aaaagcagat gcatttggct tatcatttgc agaaaaacat
    31741 cgacgtgata gtatgcatta ttttattgga gcagggaatc aatggggagc tgtttattca
    31801 tatgccatgt gttactggga agaacaaagc tggcttccat cgaaatctat ccatgctgcc
    31861 gagtttcttc acgggacgtt agagatcgta gaagaaacaa ccccagtcac attattttta
    31921 ggcgaagatg aacagagagt gttatctgaa cgtgtggcta aacttttgcc aaaaatttgc
    31981 agcaattata cattgataga cacaaaagac tatccagtag aaggtatcag tgaaaaatat
    32041 cgcggacgtg ttttgtcttt cttattgatg catgtagtga cacaacgcat cgatgctcat
    32101 gtggagcagt tgaactgcca tccattagag atacgccgct actatcgtca gtttgattat
    32161 taggatagac tggataaaaa gaatataaaa aataaagaga gcagcgataa ctgctccctt
    32221 tattttttta aaatattggc atcaattacg ttataaaaca
//
LOCUS       DAFBSV010000022        31756 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.022, whole genome shotgun sequence.
ACCESSION   DAFBSV010000022 DAFBSV010000000
VERSION     DAFBSV010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31756
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.022"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            116..547
                     /gene="mraZ"
                     /locus_tag="LLB18_000996"
     CDS             116..547
                     /gene="mraZ"
                     /locus_tag="LLB18_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HBK5244012.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            568..1527
                     /gene="rsmH"
                     /locus_tag="LLB18_000997"
     CDS             568..1527
                     /gene="rsmH"
                     /locus_tag="LLB18_000997"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBK5244013.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            1532..1933
                     /gene="ftsL"
                     /locus_tag="LLB18_000998"
     CDS             1532..1933
                     /gene="ftsL"
                     /locus_tag="LLB18_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HBK5244014.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            1934..4126
                     /locus_tag="LLB18_000999"
     CDS             1934..4126
                     /locus_tag="LLB18_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBK5244015.1"
                     /translation="MSLKNKIRRFMEKKNLNPINNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            4152..5114
                     /locus_tag="LLB18_001000"
     CDS             4152..5114
                     /locus_tag="LLB18_001000"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBK5244016.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            5128..6489
                     /locus_tag="LLB18_001001"
     CDS             5128..6489
                     /locus_tag="LLB18_001001"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBK5244017.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            6515..7603
                     /gene="murG"
                     /locus_tag="LLB18_001002"
     CDS             6515..7603
                     /gene="murG"
                     /locus_tag="LLB18_001002"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBK5244018.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            7618..8838
                     /locus_tag="LLB18_001003"
     CDS             7618..8838
                     /locus_tag="LLB18_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HBK5244019.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            8994..10319
                     /gene="ftsA"
                     /locus_tag="LLB18_001004"
     CDS             8994..10319
                     /gene="ftsA"
                     /locus_tag="LLB18_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HBK5244020.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            10342..11583
                     /gene="ftsZ"
                     /locus_tag="LLB18_001005"
     CDS             10342..11583
                     /gene="ftsZ"
                     /locus_tag="LLB18_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBK5244021.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            11600..12277
                     /locus_tag="LLB18_001006"
     CDS             11600..12277
                     /locus_tag="LLB18_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBK5244022.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            12291..12890
                     /locus_tag="LLB18_001007"
     CDS             12291..12890
                     /locus_tag="LLB18_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBK5244023.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            12905..13192
                     /locus_tag="LLB18_001008"
     CDS             12905..13192
                     /locus_tag="LLB18_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBK5244024.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            13241..14023
                     /locus_tag="LLB18_001009"
     CDS             13241..14023
                     /locus_tag="LLB18_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBK5244025.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            14044..14751
                     /locus_tag="LLB18_001010"
     CDS             14044..14751
                     /locus_tag="LLB18_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBK5244026.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            15013..17811
                     /gene="ileS"
                     /locus_tag="LLB18_001011"
     CDS             15013..17811
                     /gene="ileS"
                     /locus_tag="LLB18_001011"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBK5244027.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(17860..19386)
                     /locus_tag="LLB18_001012"
     CDS             complement(17860..19386)
                     /locus_tag="LLB18_001012"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HBK5244028.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(19401..20048)
                     /locus_tag="LLB18_001013"
     CDS             complement(19401..20048)
                     /locus_tag="LLB18_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HBK5244029.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(20232..20561)
                     /locus_tag="LLB18_001014"
     CDS             complement(20232..20561)
                     /locus_tag="LLB18_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HBK5244030.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            20738..21466
                     /gene="sfsA"
                     /locus_tag="LLB18_001015"
     CDS             20738..21466
                     /gene="sfsA"
                     /locus_tag="LLB18_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HBK5244031.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            21482..22495
                     /locus_tag="LLB18_001016"
     CDS             21482..22495
                     /locus_tag="LLB18_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBK5244032.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            22495..23772
                     /locus_tag="LLB18_001017"
     CDS             22495..23772
                     /locus_tag="LLB18_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBK5244033.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVRNKSKKERNKGARRK"
     gene            23835..26537
                     /locus_tag="LLB18_001018"
     CDS             23835..26537
                     /locus_tag="LLB18_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK5244034.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            26689..27006
                     /locus_tag="LLB18_001019"
     CDS             26689..27006
                     /locus_tag="LLB18_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5244035.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            27036..27356
                     /locus_tag="LLB18_001020"
     CDS             27036..27356
                     /locus_tag="LLB18_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBK5244036.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            27464..28924
                     /locus_tag="LLB18_001021"
     CDS             27464..28924
                     /locus_tag="LLB18_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK5244037.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            28992..29213
                     /locus_tag="LLB18_001022"
     CDS             28992..29213
                     /locus_tag="LLB18_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244038.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            29244..29426
                     /locus_tag="LLB18_001023"
     CDS             29244..29426
                     /locus_tag="LLB18_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HBK5244039.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            29426..29839
                     /locus_tag="LLB18_001024"
     CDS             29426..29839
                     /locus_tag="LLB18_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBK5244040.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            29962..31143
                     /locus_tag="LLB18_001025"
     CDS             29962..31143
                     /locus_tag="LLB18_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5244041.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(31214..31378)
                     /locus_tag="LLB18_001026"
     CDS             complement(31214..31378)
                     /locus_tag="LLB18_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244042.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            31532..31605
                     /locus_tag="LLB18_001027"
     tRNA            31532..31605
                     /locus_tag="LLB18_001027"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:31566..31568,aa:Arg,seq:cct)
BASE COUNT        10661 a         5457 c         6772 g         8866 t
ORIGIN      
        1 taaaaaaatg tttatgaata aaaaaagttg ttcccggatt tcccagaaaa ggtggtagaa
       61 agtgggggat tgtggtagac taattttagt tagtggagga atgggggggc tttcaatgtt
      121 gatgggtgaa ttccaacata atattgatgc aaaaggacgt ttaatcgtgc cctcaaaact
      181 tcgtgaagaa cttggcgaaa agtttgttct gacacgcgga ttggatggct gtcttttcgg
      241 ctatccgatg agcgaatggg aaaatctgga agctaaactg aacgaaatgc cgttggctaa
      301 aaaagacgca cgtacttttg tgcgattctt ctattcggct gccactgaat gcgaacttga
      361 taaacaagga cgaatcaata tacccagcac gttaagaaat tatgcagctt tgacaaaagg
      421 ttgcgtagtc atcggtgtat ctaaccgaat tgaaatttgg gatgagacac gatggcaaga
      481 tttttctgca gcagcagaag agaactttga cgaaattgct gaaagtatga ttgatttcgg
      541 actataagaa taggaagagg ctgactaatg actgaaacat ttcaacacta tacagtcatg
      601 ttgaaagaaa cggtagatgg attgaacatc aaaccggatg gcgtttatgt agactgtaca
      661 ctcggcggtg ccggacatag tgaatattta ttaagccaac taagttctaa agggcatctg
      721 tatgcgtttg accaagatca aaaagcaatc gatcacgcca agctgcgttt agcttcttat
      781 gtcgaacaag gtatggtcac atttatcaaa gcgaacttca gagaattaga agaacgcttg
      841 agtgagcatg tagataaggt agacggcatt ttgtatgatc taggggtttc ctctcctcag
      901 ctagatgaag cagaacgtgg atttagttat catcaagatg caccgttgga tatgcgcatg
      961 gatcagtcag ctcctttatc cgcttatcac gtaattaatg aatattccta ccatgaatta
     1021 gtaaagattt tcttccgcta tggcgaggag aaattttcca aacaaattgc tcgtgaaatc
     1081 gaacgagtac gaaaaacaaa accaatccaa acaactggtg agcttgtcga aatcattaaa
     1141 caagtcatcc cagctcccgc aagaagaaaa ggcgggcatc ctgcaaaaag aatttttcaa
     1201 gctgtgcgga ttgcagtaaa tgacgaactc ggtgccgaag aggcctcttt agaacaggca
     1261 atccggttat tgaaagtcaa tggaagaatc agcgtaatca cattccattc attggaagac
     1321 agaattgtca aaagtatgtt taaagaatat agtacggtac aagatctacc accgggactt
     1381 cctgtcatac ctgacgaatt ccaaccagaa ctgaaagtca ttactcgtaa accaatcctt
     1441 ccttcagagg aagagctaac agaaaacaat cgatcacgca gtgcaaagtt acgtattgca
     1501 gaaaaaataa gaatgaaaga ggagtagaat gatggcagaa ttaaagaaaa tgcaagatta
     1561 cgaatatgat ttacctgaat tggtggatca gccggaacaa caaatgcctg attcttcttc
     1621 gaatcaagaa atcattcttc cacaatcacc ggcaaaacga ttaaagcaga tttctgcttt
     1681 ggaaaaaatt gctgtggcaa gcgtggcgat tgctattgtt gctttatgtg ttttaacagt
     1741 tatgctgcgc acaaatatca gcggagctga aaaagaaatc acgtcaatac aaacagaaat
     1801 caatgataaa aagcaagaaa aaacgagttt agaacaagaa aaaaacgaac tttctcgtac
     1861 tgaacggatt aaacaaatcg cagaagaaaa aggattgtct attaatgacg acaatttaag
     1921 gaaagtgaag taaatgagtc ttaaaaataa aattcggcgg tttatggaaa agaaaaatct
     1981 aaatccgata aacaatcgca aaaaagtagg tatcatttta tttgctacga gtattggatt
     2041 gttcttttta tttgccgtcc gtttctcgta tatcgttatt ggaggtcatg ttgctggtac
     2101 ctcattagct gaaaaaacaa aacagttgta ccaaggaagt gaagtagtaa aagcaaaaag
     2161 aggaacgatt tatgatcgta acggtgtggc gctcgcagaa gatgcctcct cttattcaat
     2221 taaagcgata ctctcaaaaa catatacctc tggggataaa aaactgtatg ttgaagaaaa
     2281 gaattttgat aaaatagcag aaatcctgca taagaatctt tctatagaca aaaaagatgc
     2341 actgaatatt ttagaggacg gcgcaaaaaa agagctgtat caagttgaat ttggtagcta
     2401 tgggaaaaat atctcccaag aaaccaagca aaacatcgaa gcggacatga aaaaagaagg
     2461 tgtcgctggt ctttattttg tcgaccatca ggctcggatg tatccaaatg gcgtcttttc
     2521 ttctcatttt attggatacg cagttccaga caaagatgag aatggcttag ttggtaaact
     2581 aggtttggag tctgcttaca atgatatctt gagcggtaaa gatggtaaga ttatttatca
     2641 aaaagataat tttcaaaatc ctctgccagg tacagtggca gaagaagaaa aagctgtcga
     2701 cggacaagat atctacacga ctttagacag cagactacaa agttatttag aaacactgat
     2761 ggatcaagta aatgaagaat atcagccaga agaattgaca gcagtcctga tgaaagcaaa
     2821 aaccggagaa atcttggcaa tgggacaacg acctactttc aatcctgaaa caatggaagg
     2881 attgactgga aaagatgcta tctggcgtaa tttcttggta caagatagtt atgaaccagg
     2941 atcaaccatg aaagttttca ctactgcagc tgctatcgaa gaaggagaat tcaacgagaa
     3001 tgaaaccttc caatctggaa aaatccaagt agaagatgct acgatcaatg accatgactt
     3061 tggtgaaaaa ggtgtgctga ccatgcgtca agctctttca tggtcaagta acgtcgggat
     3121 ggtcatactg gaacagcgat taggcggacg atggtataac tatttacaaa aactgggatt
     3181 tggacaaagt actcattctg gattagatga tgaagtaaac ggtgctttac ctacattaaa
     3241 tattgtcgac cgagcaatga gtgcttatgg acaagcggta ggtgtgacga atttccaaat
     3301 gatgaaagct ttcacttcta ttgcgaataa cggtacaatg attcaacctc gatatatcag
     3361 caaagtggtg gatccccaaa ctggagaaga gcgaacaact caaacagaag ttctagggca
     3421 acctttttca aaagaaacaa cagaaaaagt ccgtgaatat atgagagatg ttgtcgaaag
     3481 cgaaaactac ggtagtgctt atggtgtata tagtgtacct ggatacaatg tatcggcaaa
     3541 aaccggaaca gcccaaatcg cttctgatac agggggatat caaacaggag atacagccta
     3601 cctgtattcg attgtggaga tggttccttc tgaagatcca gactatgtct tgtatctaac
     3661 aatgaaacac cctaagacat atgatcgaat ggcattggct aaaatcgcaa atccattgat
     3721 gaaacgggca atggatttta aagaaactga agaagattca gatacagaaa caaaaacaga
     3781 aaaagtatcc gtagccgatt atcgtaatct tgaagcggac gttgcagcag ctgatgctca
     3841 aaaaagtgga ctgcaacctg tagtgatcgg taatggtaaa aaagtacaaa aacaatctac
     3901 tgccaacggt gatcagttga tctctggaga aaaactgatc ctatatactg gtggtgataa
     3961 gctgatgcct gacgtaacag gatggtcaaa agcagatatc atgaagctgg ggaaaatcct
     4021 cggtattgaa gttagttttg atggagatgg ttattgtgtc aaacaagaac ttgctccata
     4081 tgaaaaaatc actgaagaca aacttagttt tactttagaa gaataagaag agaaatagga
     4141 gagaaaagag catggaatgg acacaagcat tgattcccat tgtcagcagt tgtgcaatga
     4201 caattgccgc aatgccgcta tttattggtt attttcaaat gaaaaagcaa ggtcaggcga
     4261 ttcgtgagga gggaccaaag tggcacaata gcaaagccgg aactcctaca atgggcggct
     4321 tagtgtttct gatcggctct attttgacag gaatttgggt tggagcttgg caaaaacagc
     4381 taactcctac tcttttcatc ttgctttttg tattagcgtt atacggagta atcggctttc
     4441 ttgatgattt tataaaaata ttcaagaaaa gaaacatggg actgaactcg aagcagaaat
     4501 tgattggaca gattctaggg ggaatcatct tttatcttgt ttaccgttct gaaggttatc
     4561 caggtgtatt gaatttcttc ggactagatc tacctttagg aatcatttat ggtattttcg
     4621 ctctcttctg gcttgttgga ttttcaaatg cagtaaatct gacagatggc atcgatggat
     4681 tagttgctgg cttaggaagt atctcttttg cagcttacgg tctaattgct tggcatcagc
     4741 atcagtatga tgtattaatc atttgcttaa gtgttttagg aggtttactg ggtttcttcg
     4801 tctacaacag aaaacctgcc aagattttta tgggagatgt cggttcatta gcgttgggcg
     4861 gacttttagc ggcaatttct ataatgctaa accaagaatg gacattgctt ttgattggtt
     4921 tgatctatgt tatggaaaca gcaagtgtga tgcttcaagt tacttccttt aagcttacag
     4981 gaaaacgaat ttttaaaatg tctccaattc atcatcactt tgaaatgtgc ggatggtcgg
     5041 agtggaagat tgatacagtt ttttggttga tcagcattgt gacttcgttg atcacattat
     5101 ggatcgtttg gtaggagatg acgggaaatg aaaaaaatat caacatatga aaataagaaa
     5161 gtgcttgtct taggactcgc aaaaagcgga gtaagtgcgg ccaaattatt acatgaattg
     5221 ggcgcacttg tcaccgttaa tgatggaaaa ccttttgacg aaaatccgga agcacaagag
     5281 ctgctttctt tagggataaa agtaataaca ggtagtcatc caatcgaatt gttggatgaa
     5341 gaattttcat tgatggtcaa aaatccaggg attccctaca gtcatccttt agtagcaaaa
     5401 gcccaagaaa tgggtattcc ggtaattacg gaagttgagc tagcttacga agtagcggaa
     5461 tgcccaatta ttgggattac aggaacgaac ggaaaaacaa cgacaacaac gatgacagga
     5521 ctactactga atgcaggagc agatcaagga attgcacgtt tagcgggtaa tattgggtat
     5581 ccagcaagtg gtgtagcgca agaagcaaaa tcagaagata aaattgtgat ggaattgtct
     5641 agcttccaac tcatgggaat cacagatttc cgccctcata tagcggtgat taccaatatc
     5701 tatgaagcac atattgatta tcatggtaca agaaaagaat atgtcaaagc taaatggaac
     5761 cttcaaaaaa acatgacaga aaaagattat ctgatcctta actggaatca gtcagaacta
     5821 caagaattag cgcaaagaac aaaagcacgc gtactgcctt tctcgacaaa agaagtgttg
     5881 gaagacggtg tgtatgctga cgattactca atatactata aaaaagaaaa aataatggaa
     5941 atatctgaac ttggcgtacc aggtaagcat aatgtagaaa atgcactagc tgctatttct
     6001 gtagcaaaat tgtatggtat atcaaatgaa gctatacgag aaacgttgca ttttttccat
     6061 ggcgtaccac atcgtacgca atatgtagga gaaatccaag gcagaaaatt ttataatgat
     6121 tcaaaagcaa ccaatatttt agcgactaaa atggctctaa gtggatttga aacgtctaag
     6181 gtcgtgttat tggctggcgg attagacaga ggaaatacat ttgatgaatt aattccttca
     6241 ttaaaaggaa tcaaagcaat ggtcgtattt ggccaaacaa aagaaaagtt gatggatgct
     6301 ggaaaaaaag caggcatcga gacaatagta acagccgatt ctgtagaaca agcagttcct
     6361 ttagcattag aaaacagtac agatggtgat gtagttttat tatcaccagc gaatgccagc
     6421 tgggatcaat acccaaattt tgaaactaga ggaaacagat tcatggaagc tgtgaaccga
     6481 ttaaaataga aaaagtagaa gcgagcgata aaaaatgaaa attttggtta caggcggagg
     6541 aacaggggga catatttatc cagctcttgc ctttgtcaat tatgtaaaga ctcaagaacc
     6601 gaatgctgaa ttcatgtatg tgggagcaaa acgaggtcta gaaaacaaaa tcgtccctga
     6661 tacaggaatg cctttccata ccttggagat tcaaggattt aaacgaaaaa tttccatgca
     6721 taacatcaag acggtccgat tgtttcttaa gagtatccgt caagcaaaaa aaatcctcag
     6781 tgattttcaa ccagatatcg ttatcggtac tggaggatat gtttccggag cggtagtgta
     6841 cgctgcagcc aaaatgggta ttccaacagt tatccatgaa caaaacagtg taccaggtgt
     6901 taccaataaa tttttaagcc gatatgtgga tcggatcgct ctttcattta aagatgcggc
     6961 ttcctttttt cctgaaaaca aagcagttct tgtaggtaat cctcgagcac aagaagtagc
     7021 agatactaaa aaatcagata ttttgaaaac atttgatttg gatccagaaa agaaaacagt
     7081 cttgattttt ggcggtagtc aaggagcact taaaatcaat caagcagtat cagttttttt
     7141 aagtgaatat attccttctt cttaccaagt tttgtatgct tcaggagata gatattatga
     7201 agagatccta aataaaataa atcctgaaat acaaaatatt agtgtccagc cttatatcaa
     7261 aaatatggca gaggtcatgg cttccagtga tctgctggtg gggcgtgctg gtgcaacttc
     7321 gatcgcagaa ttcacagctc tggggttacc ggcagtgttg gttcccagcc catatgttac
     7381 gaatgatcat cagactaaaa atgcaatgag tcttgttcac gcaggagcag caaaaatgat
     7441 tgcagataat gaactaacag gtgaatcact aagtcagaca gtcaacgaaa tcatgggtga
     7501 tgaagaattg caaaagcaaa tgtgccgagc ttctaaagaa caaggaatcc ctgatgcttc
     7561 aaaacgtctt tatgacttag taaaacaaat aatcaaaaaa taaaggcggt ggtcttagtg
     7621 agtaagaaaa aagaaccaaa aaaattgtct catccgtctt ctgatgaaaa caatttgact
     7681 ccttggcaaa aggctaaccg aaaatatctg gcagaacaag agatgaaaaa ccaagagcca
     7741 aaaaaagaag acataacatt agatacaccc ctttcagatt ctgaagaaga aaaaacggtt
     7801 caagaggaac agcaagaaga aagccagtcc gagaaaaaaa tcgaattttt tgaagagatc
     7861 aagcaaaaga aaaacggtgg accatataac ggttcttttt tgaaccggct gcccaattta
     7921 aaaagtcaac ggcacaaagt actatttcgt cggttagctt tgatcatcac tgtattgggt
     7981 ataccgctga tttttttgat ctattatgtt tctccttata gcaaattaca agcagttgca
     8041 gtatcaggca ataagacagt caacagccaa gaaatcatct ctgatacaaa attgtcatta
     8101 ggagaaaatg tttggggaca gtattttcat cgatctactt atatcgatcg ccttaaaaaa
     8161 gcacagccaa gaatcgaaac agcaaatata catttcaaag ggatgaatga attcgatttg
     8221 gatgtaacag aatataaaga gattgctttg atcgcaaaaa acaatcaata ctacccagtg
     8281 attgaaaatg gaacagtatt agatgaaaaa gtagcaaatc ctacaaaaaa tctccctatc
     8341 ttggaagagt tcaaagactc tgcaaaaatc aaagaattaa caaagcaata caatcagtta
     8401 tcatcagaat tacaaaaagc aatttctgaa atcaagtaca cgccaagagc aagcaataaa
     8461 aatctgatcc aattgaatat gaatgacggc aatcaagtta ttgtaaatat caataatctt
     8521 gcgaaccaaa tgaaatatta ttcgcaagta gccaaagata tggatgaaaa aggtgtgatc
     8581 gacatggaag ttggtatctt ctcgcatcct tacggtagca ctcaagaaac ggaagaatcg
     8641 ggccaatcgg aagaaacaac tgaaagtgaa gaaaatgcgg atcaaacaaa cgaatcaagt
     8701 gaagaggcag aaacgcaaaa agcacaaaca cctggatcgt ctagcacaaa cggatcatct
     8761 gattcaaatg attcaagtga aacaagtcaa atagaagata atccaagtac aactccgtca
     8821 agtttaaatg aaaattgata aaacaacttt aaaaagtaag aatgtacttt ctaaaaacca
     8881 gtaatttatg gtagaattgg aagcagtgaa tatatctatt aataagtata ttttaaaacg
     8941 gacgctagtt gttcgcttgt atatggaata gtaagtagga gggaatccca ttcatggcaa
     9001 aaacaggaat gtatgtaggc cttgatattg gaacgacatc tgttaaagtt gtcgtggctg
     9061 aatatatcga cagccaaatg aatattattg gagtaggaaa cgcaaaatca gaagggatta
     9121 accgaggcat tatcgttgat atcgataaaa cggtccaagc gatacaacga gcagtacgac
     9181 aagcagaaga aaaagcaggt atccagatca aaggcgtaag tgtcggtttg ccagcaaaca
     9241 tgcttgaagt agaaaattgc cagggaatga ttgcagttaa cggagattca aaggaaatca
     9301 ccgatgaaga tgtcagaaat gtggcttcag ctgcccttgt tcgttcaata cctcctgaac
     9361 gtcaaatcgt gtcaatattg ccacaagatt ttactgtcga tgggttcgag ggaatcaaag
     9421 atcctcgtgg aatgatcggc gtaagattag aaatgtacgg tctgttgttt acaggaccta
     9481 aaacgatcat ccataacata cgtaaatgcg tggaaaatgc cggattaatc gtcaacgaaa
     9541 tggtgattac tcctttagcg ctgactgaat caattctttc tgacggagaa aaagattttg
     9601 gtacgatcgt cattgatatg ggtggcggcc aaacaacaac ggctgttatg catgataagc
     9661 aattgaagtt taccaatctt gaccaagaag gtggcgaatt tgtcactaaa gatatctcta
     9721 ttgtattaaa tacgtcattt aacaatgcag aagcgttgaa aataaactac ggggatgcat
     9781 acccagaacg gacatcacca gatgaagaat ttccagtaga tgtgattggt cagtcagaac
     9841 cagtgaaagt cgatgaacgc tacttgtcag aaattatttc agctcgaatg gaacagattt
     9901 tcaacaaagc aaaagatgca ttggaccaaa tcgaagcatt agagttgcca ggtggcgtcg
     9961 tattgacagg cggagctgct agtcttcctg gtgttgtgga cttggcacaa gaaatcttcg
    10021 gcgtaaatgt aaaattgtat gttccaaatc acatggggct gagaaacccg gtatttacaa
    10081 atgtaataag tatcgtggat tattcagcaa acttgagtga agtgtatcaa ttggcaaaaa
    10141 ttgctgttac gggtgaaacc tcagcagctc gtcaaatggt agttgaacaa gaaacaacaa
    10201 acacatatga gagctatgaa gcacctgaag aaacaatcta cgatgagccg gaaccaaaag
    10261 agtccggaga aaatgtaaaa aataaaatca agggtttctt tacaaatatt tttgattaat
    10321 tcatcctggg aggaataaga tatggaattc tcaattgata ataatatcaa tgacggcgca
    10381 gtaatcaaag tcatcggagt cggtggtggc ggtggaaatg ctgtaaaccg aatgattgaa
    10441 gaaaacgtta aaggtgttga attcattaca gccaacacag acgtgcaagc attaaaaaat
    10501 tcaaaagctg aaacagttat ccaattaggc cccaaatata ctcgtggttt aggtgctggt
    10561 tctcagccag aagttggaca aaaagcggca gaagaaagtg aacaatcctt acgcgaagct
    10621 ttagacggtg cagatatgat tttcatcact gcaggaatgg gtggaggaac cggtacaggt
    10681 gctgcaccaa tcgttgcagg tatcgcgaaa gaattgggcg cattgactgt tggtgtcgtg
    10741 acacgtccat tcacttttga aggaccgaaa cgtggccgtt ttgctgcaga aggtatcgct
    10801 cgtttgaaag aaaatgtgga tacattatta attatctcaa ataaccgttt attagaagtt
    10861 gtagataaaa agacaccgat gcttgaagct ttccgtgaag cagataatgt tttacgacaa
    10921 ggtgtacaag gtatctctga tttgatcaca gcgccaggtt acgttaacct tgactttgct
    10981 gacgtgaaaa cagtgatgga aaaccaaggt acagcattga tggggatcgg tgtggctagt
    11041 ggagaagatc gcgtagtaga agcaacgaaa aaagcaatct cctctccatt gcttgaaaca
    11101 tctattgatg gagctgaaca agtacttctt aacatcacag gcggtttgga tatgacattg
    11161 ttcgaagcac aagatgcttc agatatcgta gcaaatgcag caactggcga tgtaaatatc
    11221 attctaggta catctatcaa tgaagaaatg ggcgatgaaa tccgtgtgac ggtcatcgca
    11281 acaggtatcg atgaatcaaa aaaggaacgc aagtctagcc gaccagctag acaagcacaa
    11341 atgcaatcac ctgctcaaaa gactgtatta gatatggatc aagctaaacc aacttcttca
    11401 gaagaagaaa acagttttgg cgattgggat atcagacgtg aacaaaatgt tcgtcctaga
    11461 gttgatgatt ccaattttga caatatcgaa aaaaaagaat ttgatacatt caaccgcgaa
    11521 gaaacaaaat ctcatggcga tgatgaatta aatacgccac cgtttttccg tcgtaaaaaa
    11581 taaaggagag gaagagcaca tgattgctga caacttgcag aaaatcaagc aagaaattca
    11641 ggattcgtgt gctcttgttc atcgtgatcc gaaagaagtt acattagtag ctgtaacaaa
    11701 atctgttgaa tccgctcaag ctgaagaatt ggttagagct ggcgttatga attgtgcaga
    11761 aaaccgagta gataaattat tagaaaagaa acaagattta tttgattttc ctgaaataaa
    11821 gtggcattta attggtaatt tacagcgcag aaaggtaaaa ttgattgtaa atgaaattga
    11881 ttactttcat gcgttggaca gtttaagatt agcagaagaa atccagaagc ggttagagaa
    11941 agaattatcc tgttttattg aagtaaatgt ttctggtgag gaatcaaaac atggaatttc
    12001 accagatgag cttttaccgt ttgtggaatc tttagctgcc tgcacaaaaa tcaaggttgt
    12061 tgggttgatg actatggcgc ctaaagaagc ttctgatgag caaatccata aagtgtttgg
    12121 tacgctgaaa gaattgcgtg atcttgttca agcaaaaggt tatgcccatg caccatgtag
    12181 tgaattaagt atggggatga gtcaagactt tcaaattgcg attgaagaag gtgcaacatt
    12241 tatccgtgta ggaacagcgc tattcaaaga cgaataaagg aggaacaaaa atgccgcttt
    12301 taaacagagg agcaattgct aattttttcg gattagctga tgaggaagag tacgaatacc
    12361 aagattatcc tgaaacaaca aaaaaggctg tacagccaac taaaaaaaat acaacacaga
    12421 atcaatcaac tcattctgta tctgctgcga atactcatga aaaacaaaaa acggcgactt
    12481 cacgtcctgt aacgcatgaa agtattcagc cggctgaaaa gaaaaaagta attgaactac
    12541 atcaatcacc tacaaaaact gtagcgaaag aaagaacagc ttcaagaacc tctacacaac
    12601 ctaaagcaaa tcttgctgga aaaatcactg taatggaacc aagagcttat tctgaagcta
    12661 tggcgattgc taaacgaatc attgctggag aagcaacctt agtgaatttt catttagtag
    12721 aagaaaaaca agcgagaaga atcgttgatt ttctaacagg aacagtttat gcactagatg
    12781 gagatatcaa acgtgttgga gatgagattt ttctttgtac accgactggg atggagattg
    12841 acagttcaac cgctcaatct tttgcagatg cgaatttgtt tgatctgtaa gaggaggaac
    12901 tacgatttat actattgcac tattacttca tttacttcaa cgggcagcct atttctatag
    12961 cattatcttg atggtatatg cattgctctc ttggtttcca ggcgggtatc aatcagggct
    13021 aggacgatta ttagctaaga tctgcgaacc gtatatcagt ttgttcgatc gtctgccttt
    13081 gaggattgga cccttggatt tcacaatttt aggggcaatc ctgatcttga acttagccgt
    13141 acaaggttta gcacagatcg ttatatggat aactgtccat ttagtttatt gattgaagca
    13201 acaaaatctt tattctcaga atagatagga ggggaaaatt ttggatgcaa atgtatacca
    13261 gcactttcgg gcagatgaac gtacatttat cgattcggta ggcgattgga ttgaacaggt
    13321 tcaaggacaa tatgcaccct atctgaccga atttcttgac ccaagacaat cctatatttt
    13381 agaaacactg attcgacaaa gcagtgattt gcgtttcatg ttttatggcg gatatgaaca
    13441 ggcagaaaga aaaagatgtt tgattttccc cgattattac gaacctgtag aggaagattt
    13501 tgaaacagca ttgtatgaaa tccattatcc tagcaaattt gccagcctaa gtcatgggaa
    13561 aatccttgga actttagtgg gaacggggat caaacgctct tactttggcg atatcatctc
    13621 ggacggtgat cgctggcaag tatttattgc aaatgaggtg gatcattttg ttgctgcaca
    13681 agtaacaaag attggaaagg ttgctgtacg cttggaacca atcaaataca cagaaatgat
    13741 tatgccgaaa gatagctgga cacaagaaag aggaacagtt agttccatgc gactagacag
    13801 tgtgatctct gagatttata atatttccag acagcggtcc aagcagctga tcgaagctgg
    13861 taaagtaaaa gtgaactgga cagaaaatac aagacctgat tttgtacttg aactattaga
    13921 tattatttca gtcagaggtt atggcagagt ccagatccaa gaacttgagg ggaagacgaa
    13981 aaaagaaaag tacagggtac tgttcggtgt attacgtaaa taaaataaaa aggtggttta
    14041 ctcatggctt taactccatt agatatccaa aataagacat tcccgacaaa aatgcgggga
    14101 tataatcaag acgaagtaga tgatttctta gatttagttg ttcgtgacta tgaggaattg
    14161 actcaaagaa atcgagaatt agaaaaagca gtcaaacatt ctgaagaaaa acttgagtac
    14221 ttcaatgaat taaaagatgc tttgaaccaa tcaatcatcg tagctcaaga tacggctgat
    14281 aaagtaaaaa caagtgcaag caaggaatcc gaagtgatcg ttacttctgc acaaaacaaa
    14341 gcagatgagt tagttgcgaa cgctgaaaaa cgtgcacatc aattaacaac tgatgcagaa
    14401 gaaaaagcaa gaaaaatctt gacagatgca acagaaaaag caagacagct tgcgacagaa
    14461 actgaagatc ttaagaaaaa aacacgagta ttccatcaac gtatcagctt gatgcttgag
    14521 tctcaattag aacaagtgaa aagtccggaa tgggatgaaa ttttacaacc attctccagc
    14581 tacgtgactg acagccatga agtgatcaaa gaagttttag caaaacagct tgacaatgaa
    14641 aatgatactg atgtaaactc agacacagga gtcatagaag cacctatgac ggcatttgat
    14701 acacaggcta ttgatatctc gatcgtgcct ggtgaaaatg aaaacgagta gaacagaaaa
    14761 gcactttgtt attcttaaag cgagccgatg agagtggaag ttcggtaaga cactgcatgg
    14821 tgaaagatcc tctacttgag acctgctttt ccgaaattag agtaagaagc agcggctgac
    14881 ctcgttattg gtcacagaga gtttgcacta gatagatgca actaaatttg ggtggtacca
    14941 cggcatgttc gtcccttgcg gctgaacatg cttttttgtg tccggaaaac aaataaagga
    15001 gtgtatggtt gaatgaaaat gaaagaaacc ttgcaattag gaaaaacaaa attccctatg
    15061 cgtggtaatt tgccaaaccg agaaggcgag tggcaaaaag aatgggaaga aaatcgaatc
    15121 taccaaaaaa gacaagagtt gaacgaagga aaacctagct ttgttcttca tgatggacct
    15181 ccatatgcca atggtaatat ccatttagga cattcattga ataaaatcag taaagacatt
    15241 atcattcgtt caaaatcaat gtctggctat cgtgcaccat atgttccagg atgggataca
    15301 catggattgc cgattgaaca agtattggct aataaaggcg tgaaacgtaa agaaatgtcc
    15361 atggcagaat acttggaaaa atgtcgtgaa tatgcacttt cccaagtaga taagcaacga
    15421 gcagatttca aacgcctagg agttgcagga gattgggaac atccttatgt tacattagat
    15481 ccttcttatg aagctgcaca agtacgcgta tttggtaaaa tggctgaaaa aggctatatt
    15541 tacaaaggat tgaaaccaat ttactggtct ccgtcaagtg agtcttcttt agcggaagct
    15601 gaaattgaat ataaagatgt aaaatctcca tctatttttg tagctttcaa tgtcaaagac
    15661 ggcaaagata ttcttgatga agatacagct tttgtcattt ggacgacaac accatggaca
    15721 ttgccagcaa accaaggtat tgctgtaaat ccaaaattta cgtatgtatt ggtggaagcc
    15781 gatggccgta agtttgtcgt agcgaaagat ttgctagaaa cagtccaatc agaaatcggt
    15841 tgggaaaatg taacagttct aaaagaattt gctggacaag aaatggaata tatgactgca
    15901 agtcatccat tctatgaacg tgaatcactt gtgattttag gcgatcatgt tactttagac
    15961 gctggtactg gattagtcca tactgctcca ggacatgggg aagatgacta tatcgctggt
    16021 agcaaatata aactatctgt agtgtcacct gtagactcaa aaggattgtt tacagaagaa
    16081 gcacctggat ttgaaggtat cttttatgac aaagcaaatc ctatgatcac tgatctatta
    16141 aaagaaaaag gagctttgct gaagctagat ttctttactc atagttatcc tcacgattgg
    16201 cggacgaaaa agcctgtgat ctatcgggca actccacaat ggtttgcatc tatcgataaa
    16261 ttccgtcaga atattttgga tgaagtagaa aaagtagagt gggttatccc atggggtaaa
    16321 acacgtttgt ataatatgat ccgtgaccgc ggcgattggg taatttcccg tcagcgtgca
    16381 tggggagtac cacttccgat tttctatgct gaaaatggag aagcaatcat cacaccagaa
    16441 acaatcgaac atgtggcaaa attatttgct gaacatggat caattatctg gtttgaaaaa
    16501 gaagcgaaag aacttcttcc tgaaggattt acccacccag gttctcctaa tggcgaattt
    16561 acaaaagaaa aagatatcat ggatgtctgg tttgattctg gttcttctca tgaagctgtt
    16621 ttacgtcagc gaccagaatt atcattccca gcagatatgt atttagaagg atcagaccaa
    16681 tatcgtggct ggttcaactc aagtatcacg actagtgtgg ctatcaatgg tgtagcacca
    16741 tacaaatcag ttatttctca aggatttgct ttagatggtg aaggccgtaa gatgagtaaa
    16801 tctttaggaa acatcattgc accagaaaaa gtgatcaaac aatttggtgc agatatcctt
    16861 cgcttatggg tatctagtgt agattatgaa gcagatgttc gtgtttctat ggatatctta
    16921 agtcaagtgg cagaagtata tcgtaaaatc agaaatacga tgcgtttctt attagcgaat
    16981 acagaagatt tcgatcctaa aaaagatact gtttcgtaca atgatttacg ttctgtagac
    17041 aaatatatga ccgttcgatt gaaccaagta atcaaagaaa tccgagaaga agggtacgac
    17101 aaatataact tcatgcatat ttaccgtaca gttatgaact tcttgacggt tgatctatcg
    17161 tcattctacc tggattttgc taaagatgta gtttatattg aagcagaaga tgattatcaa
    17221 cgtcgttgca tgcaaactgt tttctatcaa acagctgtag ctttgacaaa attattgact
    17281 cctatcattc cgcatacagc agaagaaatc tggtcattcc tgaaagaaga agaggagtac
    17341 gttcagttaa gcgagtttcc tggttatgaa gagtttgcaa accaagaaga attgatggat
    17401 acctggactg ctttcatgga cttccgtgat aatgtcttaa aagcattgga agaagcaaga
    17461 aacagcaaat tgattggtaa atctttggaa gcaaaactaa ctgtttatcc aaaacaacaa
    17521 gttcgtgaaa tgttaaaagc tttggatgca gatattgcac aattattgat cgtttcacca
    17581 gactactttg aagttatggc agcagatgaa caagtgccag ataacgctat ggtatttgat
    17641 gatgttgcta ttacagtgga aaaagcagac ggggaaactt gcgatcgctg tcgccaagtt
    17701 cgtaaagatg taggagtaga tgaaaaactt cctcatctat gcggtcgttg tgcaaaaatc
    17761 gttgaagact tctatcctga agctgtagct gaaggattcg aagaaaagta aaagggaaaa
    17821 gggggtgtga catgttcttt gtcacacccc cttttgttat caatcgttta attttccacg
    17881 ttcacgatac cagttatctg gttgccagat ccattcgaat ccgtcttttt caagtagttc
    17941 gaaagctgct ttaggtccca ttgatccagc tttgtagttg ggaaaatccg gttgtgtttg
    18001 gtcccaagct tttcgaatga catccacgat atgccaagat tgagcgactt cttcccaatg
    18061 agagaagttc gttccatcac cattcaacgc atctaatagt aatttttcgt aagcttctgg
    18121 gctattttca accatttctg cactatttct aaattccaat ttgattggtt ccgtttcaaa
    18181 tccttgccct acttctttcc cattcaagga taaagaaaat ccttcagttg gctgaatata
    18241 gatcgttaga acattaggtg gaagtgtcgt atcgtcacat ggttcatcga cagatgtttt
    18301 gaatacatta acaggaactt gtttgaatac gatgttgatc cgagtccctt tttcagtcaa
    18361 acgtttgcct gtacgtacat agaaaggaac acctgaccaa cggaagttat cgatagtgaa
    18421 tttgcctgcg acgaatgttt cagtctctga ttgagcatcc actttgtctt cttcgcgata
    18481 gcccttgaat tgtacaccat ccaattcacc ttgagcatat tgcccgcgaa cgaagttttc
    18541 taacacttct tcttcgttat aaatgcggat agctttcaat gctttgatct tttctgtacg
    18601 gatttctttt tcggaaaatg ctactggcgg ttccattgca agtaatgcta caacctgtaa
    18661 aatatgattt tgcaccatgt ctttaagtgc gccactatga tcgtagtagc ccccgcgatc
    18721 ttctacaccg aggttttcgc caaaagtaat ttggatattg tcgatatagc gattgttcca
    18781 ttgagcctca aaaatattat tggcaaaacg gatagctgag atgttttgga tcatttcttt
    18841 tcctaaataa tgatcaatcc tgaaaatatc ttgttctggg aatacttctc tgatttgctg
    18901 gttcaattca aaagcagact ggtaatcaga accgaacggt ttttctatga tcaaacgatt
    18961 gaagccattt tttgtcataa tattttgtga tttcaaatga gaaacgatcg ttccaaaaaa
    19021 ttgaggtgcc atagccaaat aatagacacg gttaccgttt aattgatagt gtccatctaa
    19081 tcggtcagac aattctttta atgtctgata atgcgttgaa tcatttacat catgggattg
    19141 atagtaaaaa tggcttgcaa aggtagttgc ttcttcatct gaaggattca atgcacggat
    19201 tgtttctttg acaacttcac ggtagtgctc atcgctccag ggacggcgag cggttccgat
    19261 tacagcaaaa tgctcgccta aatttccttt tctgtaaagg cggaacaaag acgggtacaa
    19321 tttacgctgg gctaggtcac ctgtaccgcc gaatatcgta aacaatacat ttttttcatt
    19381 agacatgtgg atacactcct ttatatttta tcgacaaaaa tcgtgctggc cgccttaaag
    19441 ctgacgggga ttttctttct atcattttgg atagtgatcg gtccttcata agctgcgatg
    19501 tcaacgatct catattcttc gttgatattc aggtcaatag tgactaagta atccaacaat
    19561 tctttttcat caagcactcg tgcgatacgc acttttgtac cgacaggata ggactccaat
    19621 gtttgtcggc gttcttcatg gacaacttcc tcttttttag gaatcgatcc tccatgagga
    19681 caatgttcag gatgattcaa atagttttct aaatgatctg caagatgttc cgaagtcaca
    19741 tgttccaata cttcagcatc atcatggact tcattccagc tatagtctaa atgttcaact
    19801 aaaaaaactt cccataagcg atgtttgcga atcagactgc tagctttttg cagtccgctt
    19861 gcagtcaatt gtacaccttg ataaggggaa tgttctacaa gctcttcttt cacaagttta
    19921 gaaatcattt cactgacaga tgcagctgag acatctagac tagatacgat ttgtttattg
    19981 ttgactttcg ttgtatctcc acctagttct aaaatgattt tcaaataatc ttctcgattt
    20041 ggtgtcatat tcgatcatcc tttcatggta aaaaaccatc attagtaagt gtaacaaaaa
    20101 aaacgttaat tgactatttt tctaaataaa aaacaaagga tttttagacg tttttacaac
    20161 aaaaaacgaa agatgataga gaagactcat tctttcgttt ataaaggata tatatataca
    20221 ttgggaggga tctatttttc agataacaac ttatatgaag tgtctgcaga ttcgtcataa
    20281 agagtttgtt cgggataaga aaagataaga taaaaaccat actgatcacg tacgactaaa
    20341 cgatattcat ctatttctac cacagatgtg ccaagagact gaccgttgat caaaaacgtg
    20401 taatcagatg taatctgtaa ttgttgtttt tgctggctat cactaaagaa ccatgtacct
    20461 tgatactttg agagtccttc tgacttttcc gcttgttttt tctttttcaa gtaaataaaa
    20521 cttgagagaa cggtaatgag tgaaccaaga aaatagatca ttttttttat caccaaatca
    20581 ctcctttatg agaaaataat cgcatagaca tattctttct tctttatttc attgtaccga
    20641 ataaaagcta aaatttctct aagactttcg actggttttt ttactgtttt tctacaaatt
    20701 atgataggat acatagtagg aagaaaggtg acataatttg aagtatcagc aagtggaaat
    20761 agcttttttt attgaccgcc cgaatcggtt tatagcacat tgtatgaaaa aagacggaga
    20821 aataattatt gcgcatgtca aaaatacagg tagaggaaaa gaggtcctga taccaggcgc
    20881 tgaagtggct attgtatttg ctcctggacc taaacggaaa accgcctatg atctgattgc
    20941 tgtaaaaaag aagggtgact ggtttaatat cgatagtcaa ttgcctaatc ggctggcaat
    21001 tgatggtatt ttagacggca cgatcctttt accaggatta actggtccat ttacggtata
    21061 caagcgtgaa gtaacttatc ttcactccaa atttgatatt tatttagaga cggtggtcgg
    21121 acaaaaagca tttgttgaag tcaaaggtat gacacttgaa aataaagcga ttggtgcttt
    21181 tcctgatgcg cccacactca gaggattgaa acatatagga gaattaacgt atgccgcaca
    21241 agatggttat gccgcttatg tcttgtttat tgctcagttc gaacatcttc atctggcaac
    21301 gatccatgaa gaaatgcaac cagcactagc tgatatggtt cgacatgcgc agcaaagcgg
    21361 agttcaaatc ctcgcctata attgtcaagt atcggcagat gaggtaactg tcaagcaggc
    21421 cattccattt gatgtagata tcccttttga agatcctata caatagaaag aaggtaaaat
    21481 aatgatcaac ttaggtatta tcggaacaaa ttggattact catcaatttg tccaagcagc
    21541 tttaagcaca aaaaaatatg aattgacagc ggtatattct agacatttgg aaaaagcaca
    21601 ggaatttggt tctcattatg aaggggatat cgaattcgca acagatttga agactttttt
    21661 caatattact catatggaca ccatttatat tgcttctccg aatagtcttc actttagtca
    21721 agctaagcaa gcaattttgg caggaaaaaa tgtgatagtt gaaaagccag ctttttcgac
    21781 gccaaaagaa atggatgaaa tcatccattt ggcaaatgaa cacaatgtgt atttttttga
    21841 agcagcaaga aatatccatg aatcaggttt taaaaagatt gccgattact taccattaaa
    21901 agacgagata atcggtgcaa atttcagcta tatgaaatat tcttcgcgct atgaccaagt
    21961 attagatgga gaagaaccga atatcttctc gactcatttc tcaggtggtg cattgatgga
    22021 tttaggtgtt taccttgtat atgcagctgt tgcttggttt ggaatgccaa aagaagtcca
    22081 ttatttccca agaaagattt ctactggtgt agatggtctt ggatggggga tcttacgtta
    22141 tgagaatttt gatgtatcga tccagccagg taaaatcggt gattcttatt taccgtcaga
    22201 gatttatttt gactcaggaa cgctagtgat gaatggagtc aatgcaattg aacaagcaca
    22261 atttcatgat cgcgcgcata aagaaatcat tgatttggcg gtaacagctg cagaaaatcc
    22321 aatggcagat gaagcagagg attttgccaa tgtcatggct catccgaaag atccagcttg
    22381 gggattgttg tatgaagagt ggatcgagct agctagaaat gtgaaccaag tgatttatga
    22441 tttaagaaaa aatggcggca tcaaattcga tgcagataat gaggaagatt tttaatgaac
    22501 gaatttgtac aagtatttcc cgaaaattgg cagaaaaaat atgaggataa agggtttatc
    22561 tcaccttctc ttattcaacg agcagttttt cagccactaa gtaataaaca aagtatagta
    22621 gcggtttctc ctacaggttc aggtaaaaca ctggcttatc tttggcctct actactaaac
    22681 gtggaaccag gtgaagcaag tgcgttggtc atttttgctt cttctcaaga actagctatt
    22741 caagtagcag atgttgcacg tgaatgggga aaagacaaag agttgaaagt ccaatctttg
    22801 gtgggcggag ccaacgtcaa acgtcagatt gagggtttga aggaaaaacc agaaatcttg
    22861 attggtacac caggaagaat attggaattg atgaaagcaa aaaaaataaa agcacatcaa
    22921 gtgaaaacaa tggtatttga tgaagcagac cagctatttg acgctgggaa cagccaaatc
    22981 attgatcaaa ttcttcatca agctccaaca gagtatcagc tagctttttt ttcagcgaca
    23041 gcagatcgtt cccttgaaag cattgaaaaa atcactggga aaacgtttga gacaattgac
    23101 gtgacagcag aggacgattc tcgaaaagga ctgagacatt actttttacg tgtaccgata
    23161 cgaaagaaag atgactactt gagacgtctc acgcatatag aagattttca tggtctgatt
    23221 ttctttaatc aactgactga attaggcgta atggaagaaa aattgctgta tagaggtgta
    23281 ccggtaggaa gtctggcctc tgatcagaac aagctactcc gaaaagcagc gctagaacaa
    23341 ttcaaaaaga aaatggtcag agcacttttg accacagatg tggcggctag aggtttagat
    23401 attacaggtc ttccttatgt agtgaatgca gaagttccgt taagtgaaga agcttatttg
    23461 catcgttcgg gaagaactgg tcgaatgggt aatgaaggaa tagtaattac actcgtacaa
    23521 gataataatc taagagattt aaaacggctt ttacgtccat caaatataac acttgaagag
    23581 atttttttat acggaggtaa gctgcaaact gagcagccaa ccaaagaaga tgcagctcct
    23641 gcagtaaata aaaagtatgc gaaaactttt tctggaaagg agcagaaccc agaatataac
    23701 aaagaaaaaa taagaaaaaa agttagaaat aaatcaaaaa aagagagaaa taaaggagca
    23761 aggcgcaaat aagcgccttt ttatgctatg attatgaaaa cgggaacaaa attggttgcc
    23821 agaggagggg ttatgtgaaa gaacgtcaag aagagatctt gcagctattg acagaaaacc
    23881 aacaaggatt gacagcaagt gatgtagctg agcgcttaac tatcgatcga agcaatgcaa
    23941 gccgatattt aagtgaacta tacaaggccc atcatattgt aaaaaccgct ggccgaccag
    24001 tcgtttactc tttgccaacg gaaaagtcaa aatctgatga agtgcatgtc gactcttcta
    24061 cgcaagtgac ttttgaaaca ctcgttggag aaaatgattc tttaaaagtc agcatacagc
    24121 aggcaaaagc tgcgattctt tatccaccgc gggggttgca tacgattatt tttggagaaa
    24181 ctggtacagg gaagtcgatg tttgctgaat gtatgtatca ttttgcaatc gattcagaga
    24241 tgctttctgc agatgcgcca tttgtttctt tcaattgtgc ggattatgct caaaatccgc
    24301 aactgctctt tggacacatc tttgggatca aaaaaggggc ttacacagga gcagctcaag
    24361 atagtcccgg tctaatagcc aaagcagacg gcggtatatt gtttttagat gagatccacc
    24421 gtttaccgcc ggaagggcag gaaatgctgt ttactttcat tgataaaggt atttaccgtc
    24481 cgcttggaga aagtgcacaa gtacatgaag catctgttca gatcattggg gcgacgactg
    24541 aatcttcaga aagtttctta tctacgttca atcgacggat tcctatggca atcaccttgc
    24601 cgaatcttgc ttcacgttca ctggatgagc gttatgaaat catctctctt tttatcaaac
    24661 aagaagcgaa tcgtttgaat caacgtatcg atatcgaaaa agaagcgatt cttgccttca
    24721 tgctttatga tgcggaagga aatatcggtc aagtgaaacg agacttgaaa ctagtctgtg
    24781 caaaatcttt tttacattac cgtactcatc atgagaaaaa gctaatcatt cgaaaagaag
    24841 aactttccct tcaagtacaa aaaggattac tgaaaatcaa ggaaataccg gaacgtctcg
    24901 accgattcat ggacagcaaa agtcagtatt tgacatttga accaggattt gctgatgttg
    24961 tctggtcaca agatccagaa cgaaacatgc aggtctataa cgatattgag gaaaaagtca
    25021 cttctctttc cgaaaccggt gtggagaaca ttgatctaga gaccctcatt tcaaaagatg
    25081 tggatgctta tttccagaca tatgtcaaag aattgactaa aagttcgatt cccaaagatc
    25141 ttttgccaga tgaaatctgg cggttaacca atcaattgta tgatgtggct gaaaaacggt
    25201 tagaccgtat ttataatgaa aaagctcgtt ttgcttttgc tttgcatctg caaagtacat
    25261 tggatcgtgt gagagaaggt catatgatcg tccacccaga tttgaataac gtacggaaaa
    25321 attttaagag ggaattccag gtagcaatcg atctttcaac gatcattgaa gaagaagaac
    25381 aagttgagat tccttttgat gaaatcggct ttattagtat gtttctttct atcaatctag
    25441 gagaaagtga gcctgttaaa gaaaacaaag tagatgttct catattgatg cacggcagac
    25501 agactgcttc aagcatgttg gagatggcac aagaactatt aggaacaaaa gtagggaaag
    25561 cttttaatat gccactggtt atggaagttc aaacaatgta tgaagaagtg ttacaatatg
    25621 tcaaaaacta tcaagagcat ttgacgaatg gcctactctt gttaacagat atgggatcat
    25681 taaacacctt cagtgatttg atttatgaag agactggcat tcggacgaaa gctatcacga
    25741 tgacaagtac catgattgtg atagaagcga tacggatggc aagtgttgga agaagcttag
    25801 aagatattta tcaaaatatc cagctttcct ttgaatcgat cgtacgtgat cagttcaaag
    25861 cggaaaagtc tgaaacttta cagcgtaaaa aagccgtaat cgtgacatgc tttactggtg
    25921 aaggagtagc tgccaaatta tatcagcgta ttatgccagt gattaatcaa aataaggtag
    25981 aactgatcca gatgcagttt ttagaacgtg aatcattcaa aaaacacatc gatgccttat
    26041 tggaagaata tgagatcaaa gcaattgcgg gaacagttga tgttgattat caaaatatcc
    26101 catttttttc agcctatgac gtttttgatg atgaaaaact aaatatttta aagcgtatag
    26161 ctgatgatga gatcccgaca gctaaaattg tcgattcact tgctggatca ttaagcgatg
    26221 tcttttctat tgatgaactg atccgttcat tgcaaaagac agttcagcag atccagaccg
    26281 atttgtcgat tatcgtggaa cctggagtag atactggaat cgttatccat ttagccttca
    26341 tgttagacgg attgatcaaa caagaaagcc atcggcaatt tgagaaactg tctattttct
    26401 caaaaattta tcgtttggaa atggatatcg ttcgggcaaa cttgatggca ctagaacgaa
    26461 aatatcaggt aaaaattcca gaagatgata tcgcatttct tacacaaatg tttcttgaaa
    26521 ataaaataaa aaaatgaaca cactaatcat actgtttaca cactaaacat ctgtgtgcgc
    26581 actataaaaa agagctaaaa agcatgaaaa cgctatttca gctctttttt ttattggcat
    26641 gcttcttgcg ttatataaaa gtgtaaaaaa ataaaaggag tgttaaaaat ggcaaaaaaa
    26701 acaatcatgt tagtttgttc agcagggatg agtacgagtt tattggtcac aaaaatgcaa
    26761 aaagcagcag aagaaaaagg gatggaagcc gatatttttg cggtctctgc ctcagatgca
    26821 gataataatt tagaatctaa gaatgtcgat gtattattat taggtcctca agtacgtttc
    26881 atgaaagctc aatttgaaca aaaacttgcg cctaaaggta ttccattaga tgtcatcaat
    26941 atgcaagact atggcatgat gaacggagaa aaagttcttg cacaagcaga aaatctaatg
    27001 aaataaatca agtatgcagt tgggggtata acaacgtgga agatcaacaa aatctagaag
    27061 ccatcatggg gttaatcatg tttggcggta atgcaaagag cgatgcaatg gaagcgattg
    27121 cggctgctaa aatcggtgat tttgagttag cggataggaa aatcgctgat gcagaagaat
    27181 cacttataca agcgcatcat gcacaaacag acatgttgac acaagaagca caaggaaatc
    27241 atatgcaagt gacattattg actgttcaca gtcaagatca cttaatgaca tctattgcgt
    27301 ttactgattt agcaaaagaa atcatcgaac tttatcgtcg cgtatacagc gaataaatac
    27361 aacttctttt ttgaacggaa gaagaaaaat ttttgaacgg attttttatt ttgttataag
    27421 gagaactctc tttatataaa aaacttatag gaggaagtaa aaaatgaacg gactatcaag
    27481 ttggatggag aaatacatcc tgccggttgc cgcaaaaatc ggagcgcaaa aacatttagt
    27541 tgctttgcgt gatgctttta tcggcacact gcccgcaaca atggcgggat cagtcgctgt
    27601 aatgatcaat gcaattattc gtgatttacc gcaacagttt aacagtacct atgctgacag
    27661 tttagcagca gacaaaggaa tctttgccgt attgaatgtc atcatcggaa tcaatggttt
    27721 tgtctggaac ggtacactag caatcgccgg attgatcttt gccttttctt gggggtataa
    27781 tcttgcccga gcttatggag taaatgatct agctgggggg atcgttggtt tagctacctt
    27841 gattcaaggt atttcctttg gtccagcatt atcagcagca ttagatgtga atgttccttc
    27901 aaatgtcgca gatgcaatca atagttctga gattggtgca acgattgcag atggcacact
    27961 gtcagttgga ttatggggtt ggctaaaact agatcatttg aatggaaacg cttattttac
    28021 agttatgatc atgggagcta tttcagtcat tattttttgt aaattgatgc ttgccaacat
    28081 tacgatcaaa atgcctgatt cagtaccacc agcagtatct aaagcatttg cagccatttt
    28141 accagcgacg atcgctttat acgtcattgc tattatcaat tatatcgtag gtcgtgtagc
    28201 tgatgggcaa ctgatcattg atttggtgca aaaatatatt gcagaaccat tcctaggatt
    28261 atctcaaggg ttgggagcag tattgatcgt cacagtattt gttcaagtat tctggttctt
    28321 tggtattcat ggaccaaatg tattggcacc agtgctagag ggaatctggg gacaagcaca
    28381 actaatcaat attgatattt tccaaaaagg ttataacgga aaaactggta caccagccgt
    28441 gttagatgca atcgaagatg gaaaagctta tatgtgggtc cgcggatcgt tcgatgcttt
    28501 tgcatggttt ggcggatcag gcggaacgat cgtcttactg atagctatct tgattttctc
    28561 taaacgtgca gattatctaa cagtagctaa attatccatt gggcctggta tcttcaatat
    28621 caacgaacca gtgatgtttg gtctgccaat cgtattgaat gcaatcatgt ttatcccatt
    28681 cttgattgct ccagtagtag caacagcaat tggatggaca gctacttatc ttggcctagt
    28741 cgctccggta tcgcagcaag tcacatgggt agtaccgccg ttcttattgt cattcttagc
    28801 aacaggagcg gattggcggg caccgatcgt aacattagta tgtatggtcg tgactttctt
    28861 gatttgggca ccatttgtca tctctgcaaa caaaatggac cctgccgcag gcgaacaaca
    28921 ataagatgaa cgtgaggagc gggacgcttt aagtttcgtt cctcataatg aattttctag
    28981 gaggaactga aatgattaca attgccagtg caatgcaaca agatgaaatc aaagaattgt
    29041 tagaaggata caatgaagaa ggaatgactt ttacatttaa agaaaaacaa ggaatcaagc
    29101 tgttctttga aacaagtgca gaagatccgg aagttgcggc taaaaaagca aaggaactaa
    29161 tcaaagcaca gccttgggga acagtccttt attttcaatc aacagctgtt tagaaaatgg
    29221 tttaaaaaga taggatggtt gagatgataa aaaacggttt atttttatgt agtattggtt
    29281 ctttgatcgt gttgtatagt ttgaatccac attcgcaaag gtatgatttg tatagtatgg
    29341 tcacaggtct ttttctaaca ggattaggaa tctatttctt catgaagggg aaaaaaagag
    29401 aagaagcaaa ggagaaaaat aactaatgga aatcacgaaa aaattaaata ttccagcatc
    29461 gtttttttac gataaagtta tggactctgt ccttttcgat gtacgtaaag cgaccggcaa
    29521 atcagtaact agaaaacagc tgaaaaattt ggagtacgtc aaacaattct cgcaaaataa
    29581 ccgggctcgc ataaaaatcg aagaagtcat tgaaaaccag tcttataagt ttcgtacatc
    29641 gacaacgaag aatgaattcg tcgttcatta tcaaatcaaa ccattggacg attcgacctg
    29701 tgaggttcat tacacagaaa aaatggagtc ttatggcatg cttcaaaagt tgaatgatat
    29761 gcttttagga acaatcttga tgtattttaa acggagacgt ttcaaaaaaa tgctagatat
    29821 gatcgaagca acgtattaaa tcaatgaaac atggtactat ttagttattg aaaaatgaag
    29881 taagctagaa ggaatttttc ataggaagat agatctttcc tgcgaatcct cactagcttt
    29941 tttgtaggaa ggggcagcaa aatgacaaac aaagtaagag agctaggtgt atcttcgatt
    30001 gaggaaatgt ttgatttagc cacttatgca tttaatgggg cagatacacc tgaaaggcga
    30061 gaacgttttc gtacacttgc ggagaattct tggaattacg gattttttga tgaggaggat
    30121 cggctaacaa gtcaagtcat ggcgacccct tttccagtga atttttacgg acaagagtac
    30181 ctaatggccg gcattggcta tgttgcttct tatccagaag caaggggaca aggcgggatc
    30241 aatcagatca tggaaaagat ccttgaagat tgccgtgatc gtaaagtaag cttatcttat
    30301 ctggcgccat tctcctatcc cttctatcgg cgctatggct atgaacaatc atttgataaa
    30361 atcagttatc aactaaacag tcgtgatgtg ccgtttatca aaaaaaaatc tggaaaaata
    30421 aagcgtatgg attttgaaga tgcaaaagct gcaatcagaa gaatttatga acagatgccg
    30481 gaaaaccaac gagctggtct gaagcgcgaa gactggtggt atacgtataa attcaagcaa
    30541 aaaggcaatt accagtttgc tttgcatttt gatgataatg aggaagcaac gggatatatc
    30601 gtttatcagc ttgcaacgtc ttcctttatt attgcggagt ggggattttt ggatcatgat
    30661 gctttttgca gccttgttcg cttcgtaagt tctcacaatg gtgcttttga aacatttgaa
    30721 tattcatgcg gctacggcgg taatgatcaa aattatctat tagaaaatcc atttgcttct
    30781 gtaatgatca caccttatat gatggcgagg atcgtagata tttctttgtt tttggaaaat
    30841 tatccattta aaaagagaca agctgcattt gccctacaaa tagaagaaga tcattatgcg
    30901 aaatggaatg aaggaatcgt ggaagtaaca atcgaaaatg gaaaaaatca tctctcaaaa
    30961 gtagaacaaa caaaactccc aatcgttcga ggaagtatcc aacatatcac gcagctatta
    31021 ttagggtatc gtaaagtgga agagttggta ttccaagaaa gaatacaggt gacaaaagaa
    31081 tatgaagaaa cgttaagctc aatcttgcca cagcaacagc caattcttaa tgactatttt
    31141 tgataaaaaa cgggtgatga caatattttt gtcaccaccc ttttgttttt catttggcat
    31201 ttgaaggaaa atgttaaagt aaatcctctt ttttcgtaaa tttgaatttt ttgttttctt
    31261 ttgttttagg gttttctttt ttgtggtctt ggattgcttc tttcgtaatc ttttcccgat
    31321 tttttttaga tgaatctaag cgttctgcgt atactttttc ttttggctta tcattcattg
    31381 gaaaggacct ccctacatta tttcattcta cctctagttt atcatctgtt aaggactagt
    31441 ggaaacgttt tgcctaactt ataagctgat ttttttagca gataagcttg caagtaaaaa
    31501 acaaacaagc tacaattgat ttattgaaat tgttcctgta gctcagtagg atagagcaat
    31561 cgcctcctaa gcgataggtc gctggttcaa ttccagtcag gaacgtataa ataacccctg
    31621 tatcctttgc ggtacagggg tttgttttgt atttgtgcca aaaatgtgcc aaactagtta
    31681 tcatttttat ataaactatc gaacacagta ttgatttttt ctttatcctg atcttcaagc
    31741 tctcgaacaa tatgaa
//
LOCUS       DAFBSV010000023        30548 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.024, whole genome shotgun sequence.
ACCESSION   DAFBSV010000023 DAFBSV010000000
VERSION     DAFBSV010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30548
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.024"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            311..1090
                     /locus_tag="LLB18_001028"
     CDS             311..1090
                     /locus_tag="LLB18_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244043.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSYVKLSADDYDIKES
                     ELPKEAVAIQDEKKTIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISAAYATKAQTVAQQMGYSNISY"
     gene            1136..2080
                     /locus_tag="LLB18_001029"
     CDS             1136..2080
                     /locus_tag="LLB18_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBK5244044.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVAIVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            2096..2875
                     /locus_tag="LLB18_001030"
     CDS             2096..2875
                     /locus_tag="LLB18_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HBK5244045.1"
                     /translation="MEETINLEEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDALGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            2887..3585
                     /locus_tag="LLB18_001031"
     CDS             2887..3585
                     /locus_tag="LLB18_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HBK5244046.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAR
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILDEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLNKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            3613..4377
                     /locus_tag="LLB18_001032"
     CDS             3613..4377
                     /locus_tag="LLB18_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HBK5244047.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEWLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQITAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            4422..5111
                     /locus_tag="LLB18_001033"
     CDS             4422..5111
                     /locus_tag="LLB18_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBK5244048.1"
                     /translation="MESEDLLSRISEVHPNQVWLDKEKVEKRYIYLFFKRMIDIVGSI
                     IGLILASPLMFYVAYRIRKEEPGSPIFFCHTRVGKNGKTFKMYKFRSMCLDAEEKLEE
                     LLDQNEIEGAMFKMKEDPRVTKIGKIIRAKSIDELPQLWNVLKGDMSLIGPRPPLERE
                     VAEYTRYDLQRLYVKPGCSGLWQVSDRNNVSFHKMVELDLEYISHRSLMYDLRLILKT
                     FYVIVKPNGAY"
     gene            6338..7018
                     /locus_tag="LLB18_001034"
     CDS             6338..7018
                     /locus_tag="LLB18_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBK5244049.1"
                     /translation="MIGIEEKKGVQKDVTIDREENLRGHRFYWIGRRAQDIFFSALAL
                     IALSPVMLITALAIVIDDPGGSPIFVQDRVGRNGKLFKFYKFRSMCVDAEAKLEALLA
                     QNEMDGPVFKIKDDPRITRVGKFIRKTSIDELPQLWNILKGDMSIIGPRPALPREVEQ
                     YGDYERQRLFVQPGLSCYWQIAPHRNELSFEEWVELDVKYINERSFITDWKIIFLTLQ
                     AVLFGYGE"
     gene            7047..8360
                     /locus_tag="LLB18_001035"
     CDS             7047..8360
                     /locus_tag="LLB18_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBK5244050.1"
                     /translation="MNIILLSGGSGRRLWPLSNDIRSKQFIKLFKDENGEYESMIQRV
                     YRQITTVDPDAKVTIATSKSQASAIHNQLGDKASICVEPCRRDTFPAILLAAAYLHDE
                     LGVGDDESVAVCPVDPYVDNSYYEGVEALEKLVQQNTANLTLMGIAPTYPSEKYGYII
                     PESSNEVSTVKEFKEKPDKATAEKYLAQNAVWNAGVFAFKLGYLLEKAHAMVDFEDYR
                     DLYSKYETLTKISFDYAVVEKETSIQVMRYNGDWKDVGTWNMMAEVMADNIKGKAVMD
                     DTCVNTQIVNELNIPILAMGCKDMVIAASGDGILISDKERSGYMKPYVEKISTEVMFA
                     EKSWGTYTVMDVQEGSMTVKVSMQAGQKLSYHYHNSRDEVWTVVAGQGKAIVDGMKQI
                     LRAGDVVTIAAGCKHTIEAVTNLDIIEVQIGETISVADKYKSSLN"
     gene            9166..9933
                     /locus_tag="LLB18_001036"
     CDS             9166..9933
                     /locus_tag="LLB18_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HBK5244051.1"
                     /translation="MGIEGGYLMSRMRFMNTEIDNLTMGEVLVEVEKMIQDRRCGYVV
                     TPNVDHIVQLETGKELQDVYKNASLILTDGKPLIWISKFYKTPIKEKISGSDIFSLLC
                     KMAAEKGYTMYFLGAAEGVAAKAADNLMKRFPGLNVVGTYSPPYGFEKDEDEMFKIDS
                     QIKRANPDMLIVGLGCPKQEKFMFYNCDRLGVPVSFGLGASLDFEAGNVKRAPKWMSD
                     YGFEWLFRITQDPKRMAKRYLVDDLKIFKLALKYRKK"
     gene            9960..10961
                     /locus_tag="LLB18_001037"
     CDS             9960..10961
                     /locus_tag="LLB18_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HBK5244052.1"
                     /translation="MIITKTPFRMSFFGGGTDMEDYFRENGGAVLSTTFDKYCYVNVR
                     HLPRFFDYSTELSYSRTERVTNIEDIEHPAIRNAMKMLDMHEIRLTYEADLPARSGLG
                     TSSSFAVGMLNAFYALKGKYADKKKLVDKAIYLERVLCNEAGGWQDQIAAAYGGFNRI
                     NFNSDGYEVLPIIITPERKKQLNNNLMMFFTGFTRFSSDVQKANNVSGTEDKRVRLKK
                     MYELVDEAEAVLTDKNRDLDDFGRLLDLTWRLKKATGGAISTGSIDELYEKGMAAGAL
                     GGKLLGAGGGGFLVFYVQPEKQNAVRSAMSNLMYIPFEFENGGTQVIHYTPEMYIPK"
     gene            10984..12270
                     /locus_tag="LLB18_001038"
     CDS             10984..12270
                     /locus_tag="LLB18_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIIA family hydrolase"
                     /protein_id="HBK5244053.1"
                     /translation="MKVVIMAGGKGTRISSVASDIPKPMIKIENKPVLEHEIECLRDQ
                     GFTDIILTVSHLGDIIMNYFGDGSGISPVTGQPFDVKIEYFLEKEPLGNAGALFRLKD
                     NLTEDFLLLNADAMFDVDFNRFVAYHREKGGLVTLFTHPNSHPYDSGLIIADKDGSVD
                     RWLVKEDSRPTYYRNRVNAGLHVISPAVLDVEINTPKIDLDRQLLKPLAGTGKMFCYD
                     SPEYVKDMGTPDRYYAVCEDFKAGRVKGKNLQNKQKAVFLDRDGTINQYVGFLRHIDE
                     FELIKGTEDAVKKINAAGYLAIVITNQPVIARGEVSFEELEEIHNKMETLLGYKGAYL
                     DAVYYCPHHPHKGYEEERPELKFDCECRKPKPGMLIQAATDFNIDLSQSWMIGDGEND
                     IKAGQAAGCKTALVGESEYGQDMTIATLSEFADKIC"
     gene            12304..12957
                     /locus_tag="LLB18_001039"
     CDS             12304..12957
                     /locus_tag="LLB18_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBK5244054.1"
                     /translation="MIDNRLQKHIDLLIKRYPTLEVIKQDIVDGYLIMEECYLNDGKL
                     LIAGNGGSAADSEHIAGELMKSFKTPRPVSREFADKLIAVDPVKGSELAKNLEYGLMA
                     IPLVAHEALSTAYINDVDGLGVFAQQLFGFGRPGDVFLGISTSGNSKNVINATVVARA
                     LGMKVIGLTGAKGGELARVADVCVKAPETETYMIQEYHLPIYHCWCLMLEDKFFGNR"
     gene            12990..14195
                     /locus_tag="LLB18_001040"
     CDS             12990..14195
                     /locus_tag="LLB18_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBK5244055.1"
                     /translation="MNVLFITTQFPYPLDNGGKIGAYNGISVLSRDYDVTVLSFTEEP
                     QYVEEGVSFFREKFNSVKFENPVIHDVHIRNNPMKLVEALAIGYCLRQPYIVSKFYDS
                     KMLQLIDEKFSNNAYWDIIFIDYLNMQSYGQYIREKYKTQFGKYILKDHNIEYDLVLQ
                     EAESSRGLKKKLLQLEYKRTRKYEEAAVNRADYCFSVCDANTEVLKKINDNSYTMLPT
                     YEMLTGVKKNIEKNTILYLGNLSWKSNMQGLVWFLESIYPNIQQRIPDVKITIVGSGP
                     VGTDFSKYSGVDYRGYVKDISHIYDDQAVLIVPLLEGSGIRIKILEAFNNEIAVVSTL
                     VGCDTIGAKDGSELFIADNEKDFATAVVRLLEDMNLNEKVRKNAKLFLKEKYSLTARQ
                     DEFSAIINS"
     gene            14325..15650
                     /locus_tag="LLB18_001041"
     CDS             14325..15650
                     /locus_tag="LLB18_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244056.1"
                     /translation="MIVAAMSYHLTGNSNVASLIAVVGVVYAIVKACNNEYLAIWVMF
                     VLGSDIWGIVPYINIGSGVLHWSDFNVIVAIFLCLRFIKVKARSRYGIVYSVMLIFIL
                     IACVQSHSIYGQDVHTTLLTARELLVVISFWPIVKIVYSERITKNEFIDLVCKFTRWT
                     MCIYWFEWILVNMGFNITFLQTGARWGTRIYIDPIFIILYFFINLYAVIYKREGYNST
                     NKSIWNCIFSLLTFVIISQGRSGILYVVITSVIMLLISLKPSKIIRFGILGIALIACL
                     VSVTQIREVVISSFVESQSSDTGNIAYRIAEQDYFENKLEGHELFGVGIPNNHDARAV
                     EYSGKTIDFESKKYNPYYLEDLGAFEIRYRFGIIAYALYIVALAISIIDAGFRRDKSV
                     AAFAGMAFMVFMALNFNLLAYITARPFGFMISLILIEISAFNDEFIYIE"
     gene            15667..16797
                     /locus_tag="LLB18_001042"
     CDS             15667..16797
                     /locus_tag="LLB18_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244057.1"
                     /translation="MNLDRLKKIANMISPIIKVINAPLAYFSGKSDYMEKGILWPTVT
                     TYSNNSRKVIQYTTLPKNVDNMAQMQWAGESFEDICIVLQGPVLEDGDFTLNTVKMYN
                     KYYPKVKLVVSTWIGLSEETECKLREAGADVVLCKKPEKTGAYNINLQLTSAYEGVKM
                     AQKLGCSYALKTRTDQRLYANDVLKYFQTLLNIFPSSDCKVVNQRLIFTTYGKSFRYL
                     PFNLCDFLVYGETSELLKLYGIQRDNRASDFGKIIYTEEKEFNKKIFTLLEGKQGVSP
                     YDVFPDFDALYKKYMFAEYYIVYNYFLENIASNESYGDLMDAYYSYLKKYAVVADSEK
                     LLLYWPKYVQYNVKFENELDFYAKLDSKKWMDIYANYTPFSQ"
     gene            16823..17908
                     /locus_tag="LLB18_001043"
     CDS             16823..17908
                     /locus_tag="LLB18_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide pyruvyl transferase family
                     protein"
                     /protein_id="HBK5244058.1"
                     /translation="MKIGIVTIVNGASFGNRLQNYATQKVLENNGYTVETINNCFDKE
                     STLSIVIKNAIYTLFKFIPHFKKSKSIWKRMYTFYQWDKQYIDYSHRKIDASKKNSFV
                     SIKNDYDYFLVGSDQIWNPKYAANKGFELLSFVPNEKRVSLSTSLGVPSIPSDLEKLY
                     VTEWNKFKSISVRENQAAKIIEDLTGTTAAVHIDPTLMLERSEWEAFQKKPDNIDENY
                     ILSFFLTNPPKDTVDVLDKVAKDLKIGVLTLDASWEYFQDITPNHFVYLISHARMIYT
                     DSFHCTVFSLLFGKPVVVFDRFDSEKMNSRLSTLLNKVNKAHFWVGKKADEAMIRAIA
                     SEPEYDIDKLMVSERECVKAYLKEYLQ"
     gene            17931..18746
                     /locus_tag="LLB18_001044"
     CDS             17931..18746
                     /locus_tag="LLB18_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244059.1"
                     /translation="MEHLSDCFGKMKIVTTSCAREYFKDDLDKSEYSCFVDSRAAMFF
                     AMGQALAKRRNVVVMLADELTSCYTALTECAFQQVDLIVFAFQTVRHEIDLASLKNCG
                     CNLINCSAQDDIDRVVSNTKGLNQTTVIKINMNCESDKDHICEYIDLPDIPVFFHGSL
                     YSPASKKKYEQYGQVSKYLGYLVGGKDAILIISHNEFLNDISVWINYYSFGEIQPKII
                     IFDSPNDYQYKWLCDLECSVAHSTNRFLSEDLALLQNNGISIVLRGDNYDIVS"
     gene            18730..20448
                     /locus_tag="LLB18_001045"
     CDS             18730..20448
                     /locus_tag="LLB18_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylase"
                     /protein_id="HBK5244060.1"
                     /translation="MISSVKNVQILVSLLKQHNIKDIVISPGSRDFQLVHSVETDSFF
                     RTYTVVDERSAAFFANGLSMAIDKPVCVCCTSSTASSNYMAAAKDAFANGIQLVLLTA
                     DRDYRRLYQMEDQMIDQVDMYGAYVRSNVDIPIVKDSDDEWYATRKINEAILELNHGV
                     KGPVQINYQLMDLSAPFVETMPEYRKITRYQEDDLLSSVEIFKQKLLSKKRIMVLCGQ
                     QEENNLSALLEEFFIKYNTIIIKDNYSNIHGEHFIKTVLVTERMSVNAFIDYCPDLVI
                     TIGKHVWSFVKYTLRDKKLKFEHWRISEDGKIVDPFNKLTSVFQCSAEFFMETVTAGV
                     NSNNNLEYYNLWKTRLSKVCYPELVYSNFYAISELVKKIPDSALVHSSILNAARLYDF
                     VSDDKALLSFANLGADGIDGCLPTFLGQAEADKTRPAYLISGDLSFFYAMNSLCGDIP
                     DNAHIFLINNHSGSEFHTNFGKFYNGSLSVDKHIAAGHISNAKDWALENNIKYITADS
                     KESLKSGLDVFINTFDSPVLFEVFTDPDTDTSVLESFYSINKVITPKMYFRKALDIIK
                     KHLHIK"
     gene            20474..21310
                     /locus_tag="LLB18_001046"
     CDS             20474..21310
                     /locus_tag="LLB18_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBK5244061.1"
                     /translation="MAIKSYIKRLLLYIRHGDPKINLDVSYLSEGAMLAGKTVIITGG
                     AKGLGFAIAKSFIAQGASVIITGRDMDSLNNAKCQLGDMCSIRAFDITDAKMYRTFFE
                     DAYETFGRIDILLNNAGISLHEDGFMSVTEKTWDKQMDTNLKGVYFFTQEFIKFVKEK
                     NQMQANIIMMSSERGLCGDSIPYGLSKAAINSLVVGLSKKYISEGIRVNGIAPGVTAT
                     AMTGISEKGNLYNPATIGYRYFLPEEVAQVALFLASSLSNCISGEIIACDQGQYLSRN
                     WG"
     gene            21315..22748
                     /locus_tag="LLB18_001047"
     CDS             21315..22748
                     /locus_tag="LLB18_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBK5244062.1"
                     /translation="MGILLKKYNSLSEPAKASIWFTLCNVLQKGILFLTTPIFTRMLS
                     TAEYGKYTIFISWYSIIAIFTTLNLSAGVYNKGLIKYENKYALTSSFLGLSSFISLCA
                     LMLYLPFRTVINGLLDLSTEFVILILIESIFEPAFLLWSVKERFDYKYQKLVLITVLM
                     AVLNPGLGIILILSFGEYAIWRVRAYVVVNVVVGMFIGIGILAKGKKLFDKEYWTYAL
                     RFNLPLIPHYLSMTLLNQVDRLMINSMVGASEAAIYSIAYTISSMMNIITTAINGSFI
                     PFTYKAIKDGVYEKIKSVANQLLVLIFVLCSFTMLFGPELIWVVGGEKYMDAVWIIPP
                     VAASVFFMFLYPLFGNIEFYYEKTNYVMFASCVGSIAKIISNYVSIPRFGYISAGYTT
                     LICYMLFSFAHYMFYKKILRENGIKEDMYNIKNIIFLSVLMIVLTIGMTILYFSTILR
                     YSIIIGLVIVAFLKRTQIMKILKNIKN"
     gene            22786..24426
                     /locus_tag="LLB18_001048"
     CDS             22786..24426
                     /locus_tag="LLB18_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HBK5244063.1"
                     /translation="MRLLIPSAKIVPEELHHLGKLPAIIYPINQKIVFDYLYDQYKDV
                     CSAIDIACYEKMDKVARRLDKYIKSKTVNIIQLKELGDLGRTIYDSLIGCDEPVIINF
                     ADTIINDNIYSLECDSFFYAEDYYSNTWTFFEEKDGDIISVLDKNELKEDDGKKHKLF
                     SGVFQIMDAQYFRECLRKALMSNVVNVNSFYQALQEYSKRYEFLSIKTNNWFDIGHAD
                     KYYNSKLEVKAREFNHISIDKDRSILRKISEDVEKFIGEIKWYLKLPAQVEYVRPRIF
                     EYSTSYINPYVSMEYYSYHTVHELFLYSDLTKKQWIDIFNRIRFVCSDFKRYSVSGDN
                     IQKSLKDMYLDKTFQRFNKLRKDPRFTEFFSSDIQINGVRYKSLDQIEALLSVSVPRE
                     LFDITQFNIIHGDLCFANIMVDNTFSFIKVIDPRGKFGDFDIYGDYRYELAKLFHSVD
                     GKYDFIIKDLFTIKYDPKKAIIDYIVQDRKRDYDLYEVFYSVFKDEIGSDLKKIELIE
                     ALLFLSMIPLHGESLNHQMAMLATGLEILGRVVPDIYC"
     gene            24514..24912
                     /locus_tag="LLB18_001049"
     CDS             24514..24912
                     /locus_tag="LLB18_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HBK5244064.1"
                     /translation="MFKDYAFVFDIDGTLCPIKKKDEKYEDLVPYANMVEKLRYYKEN
                     GAKITLFTSRNMNSYHGNLGVINANTAKILLAWLDKWEIPYDEILYGKPWPGHKGFYV
                     DDRTVRPDEFLSCTLDQLDEICKKSKLKSE"
     gene            24937..25653
                     /locus_tag="LLB18_001050"
     CDS             24937..25653
                     /locus_tag="LLB18_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBK5244065.1"
                     /translation="MTVIITMAGLGSRFRKVGYTVPKFMIEAKGKTLFDWSLDSLLDY
                     NSHVEKYVFVVRKEDDATVFIKEHCSLYGIENVEVVEIDYMTDGQATTCMLAIPYCAP
                     DNAIMVYNIDTYVEPGEMKYVDISGEGHIPCFHADGDHWSFAKLNEYGDVVEVREKVR
                     ISNNCTLGAYYFSSAKLYASLYEEYYADERHLEKNEKYIAPLYNYMIEKGMKVTISIV
                     DKSKVHVLGTPEELDVFLNE"
     gene            26885..27464
                     /locus_tag="LLB18_001051"
                     /pseudo
     CDS             26885..27464
                     /locus_tag="LLB18_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317850.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
     gene            27524..29176
                     /locus_tag="LLB18_001052"
     CDS             27524..29176
                     /locus_tag="LLB18_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBK5244066.1"
                     /translation="MDHNANYYHWLTNANAEIVEELRSYSEKDIEDSFYKNLSFGTGG
                     LRGTIGAGTNRMNVHTVGKASQGLSDYLNKTYETPSVVVGYDSRIKSDVFAKVAADIF
                     AANGIQVHLWPELLPVPTVSFAIRYLKASAGVMITASHNPSKYNGYKVYGAGGCQITT
                     EAAAEILAEIEKLDIFADVKMGGDASRIASIQPEVLTAFIEEVKGQSVLFGEEVDKNV
                     AIVYSPLNGTGLVPVTRTLAEMGYSNVTVVEEQRLPDGNFPTCPYPNPEINEAMSLGM
                     EYAKKYNADLLLATDPDCDRVGIAVKNAEGDYVLLSGNETGLLLLDYICSQRIKHGKM
                     PTDPVMVKTIVTMDLGERIASNYGVRTVDVLTGFKFIGEQIGMLEKAGKVDSYIFGFE
                     ESYGYLSGSYVRDKDGVNAAYLICEMFSYYKTQGISLFDKLNEIYAKYGYCLNTLHSF
                     EFEGAAGFTKMQKIMVEFHKGLDMIGGKKVIETLDYSTGLNGLPKSDVLKYLLEGNCS
                     VVVRPSGTEPKLKTYISVSAESKEAAEVMEAVMAAELAEMFK"
     gene            29520..29885
                     /locus_tag="LLB18_001053"
     CDS             29520..29885
                     /locus_tag="LLB18_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HBK5244067.1"
                     /translation="MYYFQQSYLPAILNKAISIGDTGVHIFFFCSGFGLYLSYLKKPI
                     TLGEFLQKRFIKIYIPYIIVITVSVLLPYMTQDLNAAKVYLSHVLLFKIFLPVYEESL
                     GPFGLFRQLFSSISYSYQL"
     gene            29973..30416
                     /locus_tag="LLB18_001054"
     CDS             29973..30416
                     /locus_tag="LLB18_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244068.1"
                     /translation="MEAYEFLGAALRNIFGNLLSACLVAEYLVKRKIVRFNNIFVIMA
                     SIVGIGFAGISKIIGGLMESINDIFAFFGYGAIAILMYQVIPFRKIMPRISRYSYDIY
                     LLHILVFSTIHQIIPNLVLAAFVSIPITLVLSYYYSIMLYRLKLK"
BASE COUNT         9952 a         4443 c         6564 g         9589 t
ORIGIN      
        1 tattattaat tcaatgttaa tttttttgtt attttatttt ttgtgtaact tttaaaaaca
       61 cctatgaaaa ttaaggaaat aaaaatgaaa tcgattaatt gttatcttat taatgtttta
      121 tttactttta aatcataaat tgccctagtc aagaaaacag tttgtggtat gattatatag
      181 ggaaaacttg tttacaaata tttctgtgaa tatattagtt taattatgtt ttttaaaata
      241 aaaagctgtc atttttatgt aagtgaatta tatcttaatt tatctatcat caatacttag
      301 gagtgaatct atggaaaagc cattcgtcaa gtcattgact gctgtggcgg taggtgcagg
      361 tgctattgcg atctgtttgt ttggttacca tatcaataat cagcggcaac atcagcaacg
      421 gatcaattat gcagaatctg ccatcaccaa tcaaaaagac accttgactt ctttatcaaa
      481 agaagtagac aagctgtata gtacaaaaga aaaaattttt ctaaaccctg aaataacaga
      541 agaaacaatc acaagtttgt caaataagct atcctatgtc aaactttcag cagatgatta
      601 cgacatcaaa gaatcagaat tgcctaaaga agctgttgca atccaagatg agaagaaaac
      661 aatcgtgaca cagttagata gtgcagaatc aaaactgaag atccagacag ctgtcaacga
      721 tttgtttact aaaaatgtat caaactggca gcaagctgta gacgatgtca tcatcaaaga
      781 aaaggtgaca agtgcagatg tcgctcgtgt acgtgaaaat atgagctttt ttaaagatag
      841 tccttggaaa acggttgtta tgcaatattt aggattcgct gatactcaga tcgcgcaagt
      901 cacgcaacta gatcagttat tcgatacgat gttgaaggat ggtcaagtga ctgccaccgc
      961 tacttacgat caatatttga cggcgctcag tcaaatagag cagatccgga atgaaaaaat
     1021 aagcgcagca tacgcaacaa aagcacaaac tgttgctcag caaatgggct atagcaatat
     1081 aagttattga cagttaaaac gttgattcaa gcaaggttag caaacggagg aaactatggc
     1141 aagacgaaga agaaaatcaa gagggaaaaa aatatttctg attattttag cagttcttat
     1201 cgtattagta ttagcaattg taggagtagg agcaaaatta tatctggatc tctcacattc
     1261 tattgagaaa acttacgaat cagtggaacg aacccaagga gaacgaacga aaccagttga
     1321 tctggacaaa caagaatctt tctctgttct attgatgggg attgatactg gagatttagg
     1381 tcgggtcgat caaggaagat cagatacgat gatggttgcc atagtcagtc ctgaagacaa
     1441 acagacaacg atcgtcagca ttcctcgtga tacgtatgtc gacatcgtag gtcgtgacac
     1501 aaaagacaag atcaaccacg cttacgcatt cggcggagct gccatggcga tggataccgt
     1561 acaaaaatat gtagacatcc caatcgatca ctatgtctct atcaatatga aagggctaaa
     1621 ggaacttgtt gatgcagttg gtggtatcga agtcaataat gacctcactt tctcacaaga
     1681 tggctatgac tttacaatcg gtaaaatcac attgaacggg gatcaggcat tatcttattc
     1741 tcgtatgcgt tatgaagatc caaatggtga ctatggtaga caagagcgtc aaagaaagat
     1801 cgtagaaggt gtagcaaaaa aagtattgag tttaaacggt gtcagcaact atcaatccgt
     1861 tttgaatgct ctagagtcga atatgaaaac agacatgagc tttgatgaaa tgaaaaaaat
     1921 cgctttagat tatcgggagg catttggtac gatcaagcaa gatcagctgc aaggagaagg
     1981 ctttatgcaa gataatatct cctatcaaaa agtcagtgat caagaacttg atcgtgtaaa
     2041 aaaagaatta aaagatcaaa tgaatctaga gaataaatag gaaagtggag aaaaaatgga
     2101 agagacaatc aacttggaag aaatttttga aacattacgc aaacacttgg taacaatcat
     2161 catctcaatg tttgctggct tggccatctc aggaatcgta acatttttca tcttgacacc
     2221 aaaatacagt tcacaagcac aattgatcgt gacactgcca caatcagaca cagcaaatgt
     2281 caatgatgtc aatacgaacc tgcaaatgat caatacgtat aaagatatga tcgtcagtga
     2341 tttagtacta aatgaagtca aagatcgttt agaaacagaa gacaatgtga aaatgactgc
     2401 tggacaaatc aaagatgcga tctccgtcaa tcagtcacaa aattcacaaa tgttctcgat
     2461 ccaggcaata agcacgaatg cagtgactgc tcaacagatc gctaacacaa cttcacaagt
     2521 tttccaagag aacgcaaaag acgtgatgaa tgtcgataaa atctcgatta tttcaggtgc
     2581 agttgccaat acgacacctg tttcgccaaa taataaattg aatctagtga ttggcttagt
     2641 attaggaatg atggtaggcg taggtctggc attcttattc gaattacttg atcggacagt
     2701 gaaagatgaa aaatatgtga cggatgcatt aggattccca atcttaggaa cagttccaga
     2761 aatgtcagcg aaagaattga acgctggtat ccgtaaaaaa ggaacagctc ctgcacgacc
     2821 aaaagctaca aacgataaaa cagccccatc acgcagaagc cgctcaagag tctaggagga
     2881 agaaaaatgg cacgaacaca gaaacaaaaa gcagcacaaa ctcatgcagt cagtttgatc
     2941 acattaacaa acccatcttc accaatcgcc gaacaatatc gtacgatccg gacgaatatc
     3001 cagtttgcct ccgcagctgg tcagcaaatc aaaacgattg tcgtgacttc atcaggtcct
     3061 ggagaaggaa aatccaccac tgcagcaaac attgcagtcg tttttgctaa atccggtcaa
     3121 cgagttctac tagtcgatgc agatttacgt aaacccgtcg tctataagac attccagctg
     3181 aacaatgcca ggggattaag tacagcactt agttcatcag gaagtgtagc agatgtaatc
     3241 caacgaacgc cagtcgagaa cttgtcgatt ttgcctagtg gacctaagcc acccaaccca
     3301 tcagaattgt taagttcgcc aagaatggat cagatcctag acgaagcaag acagttattt
     3361 gacgtggtga tattcgatat gccaccagta gtagccgtaa cagatgcaca gatcatgtct
     3421 tcaaaaacgg atggcacttt attggtcgta cgtgaaaata catcacgtaa agaatcattg
     3481 aataaagcaa aagaactgct agagatggta caagcacgag ttttaggtgt tgtatacaac
     3541 ggagcagaac atagcaaaga tgctggttat tactacggaa attaaggaat aagaagagag
     3601 gagacaagag aaatgatcga tctacattgc catatcctac caggaatcga tgacggggca
     3661 gaaaacttag aagcaagtat tgcaatggct gaaaaagcga ttcagcaagg catcacgcat
     3721 attttatgca caccacacca caataatgga aaatacagca atgaaaaatc acaagtcatt
     3781 tctctagtcg cttcgttaca agccgaatta gagaaaagac agttgccttt gacgttattg
     3841 gaaggacaag aagtacgtat taccggaacg ctcatcgaag acatccaccg agatgaaatt
     3901 ttatttacag atttagatga tacatatctt ctgatcgaat ttccgacact ggaagtgccg
     3961 ttatatgcag aatggctttt ttttgagttg ttagaactag gaaagacacc agtgatcgtc
     4021 catccagaac gcaacgcgca ttttcgagaa gacccaaatc atttgcttcc gttcctagat
     4081 atgggatgtt tggcccaaat tactgcgcca agttatgttg gtgtatttgg caaagacatt
     4141 cagaaaacag ccaaaacaat ggtcaaacat aatctcgtgc agatggctgc ttctgatgcc
     4201 catggggtct ctaagcgtac cttttactta aaagagtgct atgagcagat tgctaaggac
     4261 tttggtaagg aaaaagtagt acagatgaaa caagtcgcaa aggatctgat caacggggat
     4321 gaaatcagtt atccagtcta tgaagaggta aaaaagaaga agtttggttt attttagttc
     4381 tttattcgta gataaaaagg aaatgaggag agagggaaag tatggaaagt gaagatttat
     4441 tatctcgtat tagtgaagta catcctaatc aagtttggtt ggataaagaa aaagttgaaa
     4501 aacgatatat ctatttattt tttaaaagaa tgattgatat tgtaggaagc attattggtt
     4561 tgattttagc ttctcctttg atgttctatg tagcttatcg aatcagaaaa gaagagccag
     4621 gaagtccgat atttttttgc catacacgtg ttggtaaaaa tggaaaaaca ttcaaaatgt
     4681 ataaattccg ttcgatgtgt ttagatgctg aagaaaaatt ggaagaatta cttgatcaaa
     4741 atgaaataga aggtgcaatg ttcaagatga aagaagatcc ccgtgtcact aaaataggta
     4801 aaattatccg tgccaaaagc attgatgaat tgccacagct atggaatgtt ttaaaaggcg
     4861 atatgagtct aattggtcca cggccacctt tggagaggga agtagctgag tacacgagat
     4921 atgatcttca acgcttgtat gtaaaacctg gttgttcagg tttgtggcaa gttagtgata
     4981 gaaataatgt tagtttccat aaaatggttg agttggattt agagtatatt agtcatcgaa
     5041 gtttaatgta cgacttgagg ttgattttaa aaacgtttta tgttattgtc aagcccaatg
     5101 gagcatatta gttagggata gaatgatgga ttgttaataa aaaagattac acatgttcat
     5161 attatcgttt caaaagtaat aactgtaatt atggagggtt tgaatcactt gtagaaaatc
     5221 taaaaaaaga aaggtgaatg gggcaattca gtatcattat tcttatataa aagaaaatat
     5281 tcgaaatttt gggatgatac cactcttaaa tataatgatc taaatgcttt aatattggta
     5341 tatccgatat aggaactgac gagctattta gtatgataca aaagtatatt gatagccatt
     5401 aataaatttt ccaaaaaata atgacagcac accaattttt ataatttagc ttgttgaatc
     5461 ggtatgttca tgggacggtt caaaaaaaga atcgaaaaaa taaacggtaa aattttagtg
     5521 aatcctatgt aataaaattt ggatagatgg aaaaacagca cataaggagg ctgagtttgt
     5581 tgtcatttct gctcctacaa actatggtag tgaatgtgtt attgaattag tgatgtctgt
     5641 tacttcagag acattgggga taattaactt cactatacct gtagggtata caaaaaatgg
     5701 aagaaaaaat attatcaata gattttattt agttcagaat ttttacgtgg aagtaaatta
     5761 ttgatgataa tctttatcca attagaatta ttatcgtagg atgtgatgat gatagccgtg
     5821 aagttgttca agtatttacc aatgtctaca acgcagaaaa ttagtttggg tttttcggat
     5881 tggaaaattt caatgtataa aatcataaat ttgctgtaaa tagacagttt ggggtagtaa
     5941 tagcccaata aattgttcga taaactcatc tttggggtga gaatagctca atcattgaat
     6001 ttcaaacctg cctttggggt gggattagag gtcaatatgt acctacataa tactttttgg
     6061 aaaatgatgg tgttgagaat gtaagtacat ttcaatgtga aattctaata tagccccaaa
     6121 cgaggtcaat aaaaatgacc taaactcgta tttctcccct aaacgaggag gagatagata
     6181 tgaaaattga atgtgccggc gttggagttg gctgctttta gtaggaatga acatggttcg
     6241 atgagaactg tttcagatag agtggtcgat gatcacaggc ctttaagtcg tttacagatg
     6301 atgagacttg taaaaataga gggacgaatg gaaaaagatg attggtatag aagaaaagaa
     6361 aggtgttcag aaagacgtaa caattgatag ggaagagaat cttaggggac atagattcta
     6421 ttggattgga cgcagagcac aagatatctt cttctcggct ctagctttga ttgcattgag
     6481 ccctgtgatg ctaattacag cgctcgccat tgtgattgac gatcccggtg gcagcccgat
     6541 ttttgtgcag gatagagttg gaagaaatgg aaagctgttc aagttttata aattccgatc
     6601 tatgtgtgta gatgctgaag caaaattaga agccttgttg gcacaaaacg agatggatgg
     6661 tccggtcttc aagattaaag atgacccaag aatcacgaga gttggtaaat ttattcgaaa
     6721 gacaagtatc gatgagttac ctcagctctg gaacattctt aaaggtgata tgagtattat
     6781 tggacccaga cctgctttac cgagagaggt ggaacaatac ggtgactacg aaaggcagcg
     6841 gttgttcgta cagcctggtc ttagttgcta ttggcagatt gctccacatc gtaatgaact
     6901 gtcctttgaa gaatgggtgg aacttgatgt gaagtacatc aatgaaagaa gctttatcac
     6961 ggactggaag attatcttct tgactttaca ggctgtatta tttggatatg gtgaatgatt
     7021 atatatagta ttaggagttg aaatatgtga atattatttt attatcgggt ggtagcggta
     7081 ggcggttatg gccgctgtcc aacgatattc gtagcaaaca attcatcaaa ctgtttaagg
     7141 atgaaaatgg cgaatatgaa tctatgattc aaagagttta tcgccagatt acaactgttg
     7201 acccagatgc aaaggtcact attgcaacaa gtaagtctca ggctagtgca atccataatc
     7261 agttgggaga taaggcttcg atttgtgtag aaccttgtcg tagagatact ttccctgcaa
     7321 ttttgttagc tgcagcatat cttcacgatg aacttggcgt aggtgatgat gaaagtgttg
     7381 cggtttgtcc tgttgatcct tatgtagata attcctatta cgaaggcgtt gaagcccttg
     7441 agaagttggt gcagcagaat acggctaatt tgactttgat gggtattgca cctacatatc
     7501 ctagtgaaaa gtacggttat atcatccctg aaagttctaa cgaagtaagt actgttaagg
     7561 agtttaagga aaaacctgac aaagcaacgg cagagaaata tttagctcag aatgctgttt
     7621 ggaatgccgg tgtatttgcg ttcaaacttg gttacctgtt ggaaaaagct cacgcaatgg
     7681 tggattttga agattatcgt gatttgtatt ccaagtatga gactttaacc aagatcagct
     7741 ttgactatgc tgtggtcgaa aaagaaacga gcattcaagt gatgcgttat aacggggatt
     7801 ggaaagatgt cggaacttgg aacatgatgg ctgaagttat ggctgataat attaagggga
     7861 aagctgtaat ggatgatacc tgtgttaata ctcagattgt gaatgagttg aatattccta
     7921 ttcttgctat gggctgcaaa gatatggtaa ttgcagcaag tggcgatgga attctgattt
     7981 ctgataaaga gcgcagtggc tatatgaagc cgtatgttga gaaaatcagt acggaagtaa
     8041 tgtttgcaga aaaatcctgg ggtacatata ccgttatgga cgttcaggaa ggctccatga
     8101 ctgttaaagt ttctatgcag gccggacaga agttgagcta ccactaccac aattctcgcg
     8161 atgaagtttg gactgttgta gcaggacagg gtaaagcgat tgtagatggt atgaagcaga
     8221 ttcttcgtgc gggtgatgtg gtgactattg ccgcaggatg taaacataca atcgaagccg
     8281 tgacaaatct ggatattatc gaagttcaga ttggtgaaac tattagcgtc gctgacaagt
     8341 ataagagttc tttgaactaa aagttcgcga ggtagttatt atggagatac taaaatttca
     8401 acccgtgggt aaagattatc tttggggtgg agaacggttt aagacggaat ttggaaaaaa
     8461 ttgacttaac accattaagc ttatacgtgg gaatgcttag ttcatctaga cgataactac
     8521 gtacggaaat atcaaatatg aaggacagaa tggtaaaacc gagttgtggt atgtattgga
     8581 agctacaccg gggggtgatt tatgcttttg agtacgatgt aacagaagaa atgttacgaa
     8641 atgctgtgat ggacagatca cttgggaaac atttatataa agaagaagta cacaagggag
     8701 atctttttta tgtcagttca tggtattggc gctggagtat tagtggctga aatacaggaa
     8761 agctcaaatg ttacctatcg agtttacgat tatgatcgag tagataagaa tgataataag
     8821 tgagaattgt actttgaaaa agcgattcag gtaatgaata tggaagccac tttgaaattg
     8881 gagaaaagaa ataagctcat tcatttttat cctggtggct ctcgtgaaat actgtgtaga
     8941 tgtaaatact gtgagcccga aagaatccaa gtaaagacgg ggttttcgtt ctcggtaaaa
     9001 gaggaatctt ttcaagttct tttatgtata tcgggggacg gacaagttga gtcggcaaat
     9061 ggtgttatga aactcattag atttgtaaaa aagatattgt atgtttttgc caacgaatat
     9121 tggaagatgt taagtgttga gcgatgcgga cttactgaaa attagatggg gatagaggga
     9181 ggatatctaa tgtcacgaat gagatttatg aacacagaaa ttgacaatct tacaatgggt
     9241 gaagtattgg tagaggttga aaaaatgatt caagatagga gatgcggata tgttgtaact
     9301 ccgaatgtgg atcacattgt tcagttggaa acaggaaaag agttgcaaga tgtttataaa
     9361 aacgcatctt taattttgac ggatggtaaa ccattgattt ggatttcaaa gttttataag
     9421 acaccaataa aagaaaaaat atcgggatcc gatatatttt ctttactgtg caagatggct
     9481 gcagaaaagg gatacacaat gtatttttta ggtgcggcag agggcgttgc ggctaaagcg
     9541 gcagataacc tgatgaaaag atttccggga ttaaatgttg taggaacata ctctcctcct
     9601 tatgggttcg aaaaagacga agatgaaatg tttaaaattg attcccaaat taaacgagca
     9661 aatccagata tgcttattgt gggtttgggt tgccctaaac aggaaaaatt tatgttttat
     9721 aactgtgata gattgggagt acctgtgtct tttggtctag gagctagttt ggactttgag
     9781 gcagggaatg ttaaaagagc accaaaatgg atgtcagatt atggatttga gtggctgttt
     9841 agaattactc aggaccctaa aagaatggca aaacgatatt tggttgatga tttaaaaatc
     9901 tttaaattag cactaaaata tcggaaaaaa taaactatat tcaatgagga caatgaagta
     9961 tgattattac aaaaacacct tttcgcatgt ctttttttgg cggcggaacg gatatggaag
    10021 attattttcg agaaaatggc ggtgcagtgc tttccactac ttttgataag tactgttatg
    10081 tgaatgtgcg tcatttgcct agattttttg attacagcac agagttatca tattctcgta
    10141 ctgagagagt aacaaatatt gaagatatcg agcatcctgc aattcgtaat gcgatgaaaa
    10201 tgctagatat gcatgaaatt cgccttacat atgaagcaga tcttcctgca cgttctggtc
    10261 tgggtacatc tagttctttt gccgtaggta tgttgaatgc tttctatgct ttgaagggca
    10321 agtacgctga caagaagaaa ctcgttgata aagcaattta tcttgaaaga gtcctttgta
    10381 atgaagcagg cggatggcaa gatcagattg cagcagctta tggtggcttt aaccgaatca
    10441 atttcaactc agatggctat gaagtattgc ctattattat tacgcctgag cgtaaaaagc
    10501 agcttaacaa caacttgatg atgttcttta ctggattcac cagattttcc tctgatgttc
    10561 agaaggcaaa taatgtcagc ggcacagagg acaaaagagt aagactgaaa aaaatgtatg
    10621 agcttgtgga tgaagcagaa gcggttctga ctgataagaa cagagatcta gatgatttcg
    10681 gcagactgct tgatctcact tggagattga aaaaggctac cggtggtgcg attagcactg
    10741 gaagtatcga tgaactttat gaaaagggca tggctgctgg tgcattgggc ggtaaacttc
    10801 tcggagcagg tggcggcggt ttcttggttt tttatgttca gcctgaaaaa caaaatgctg
    10861 tgcgttcggc aatgagtaat ttgatgtata ttccgtttga atttgaaaac ggtggaacac
    10921 aggttattca ttacacaccg gaaatgtata ttccaaaata aagaaatcag cgaggataag
    10981 aatatgaaag ttgttattat ggcaggcggt aagggaactc gcatctcatc ggttgcaagc
    11041 gatattccaa agcccatgat taaaattgaa aacaaaccgg tattggagca cgaaatcgaa
    11101 tgtctgagag accagggatt cacagatatt attcttaccg ttagccatct tggcgatatc
    11161 attatgaact attttggcga tggttctgga atttcaccag ttactggtca gccctttgac
    11221 gttaaaattg aatacttttt ggagaaagag ccattaggaa atgccggtgc attgtttcgt
    11281 ttaaaggata atttgaccga agacttcctc ctgctgaatg cagatgcgat gtttgacgtt
    11341 gatttcaacc gatttgtagc atatcaccgt gaaaagggtg gcttggtgac attgtttact
    11401 caccctaaca gtcatccata tgacagcggt ctaatcattg cagataagga tggctctgta
    11461 gacagatggc ttgtaaagga agattcccgt ccaacttatt accgtaacag agtaaatgcg
    11521 ggactccatg tgattagtcc tgctgttctt gatgtcgaga taaacacacc taagattgac
    11581 ttggaccgtc agttattaaa gccgttggca ggaaccggaa aaatgttctg ctatgatagt
    11641 ccagaatacg taaaagacat gggtacccct gatcgttatt atgctgtctg tgaagatttt
    11701 aaggctggaa gagtgaaggg caaaaatctt cagaataagc agaaagctgt tttccttgat
    11761 cgtgatggaa cgattaatca atatgttggc tttctgcgtc atattgatga gttcgaacta
    11821 atcaagggta ctgaagatgc agtgaaaaag atcaatgccg ctggatatct ggctattgta
    11881 ataacgaatc agccagtaat tgcaagaggt gaagtttctt ttgaagaatt ggaagagatc
    11941 cataacaaaa tggagacact tcttggatat aagggcgctt atttggatgc agtttattat
    12001 tgcccgcatc atccacataa gggatatgag gaagagcgcc cagagctaaa attcgattgt
    12061 gaatgcagaa agccaaagcc cggaatgtta attcaggcag ctacggactt caacatagat
    12121 ttgagtcagt cttggatgat tggcgatggc gagaatgata ttaaagcggg ccaagccgcc
    12181 ggctgtaaga ctgcattggt tggcgagagt gagtatggac aggatatgac catagcaacc
    12241 ctgagtgaat ttgcagataa gatctgctaa gggatgtttt atcacgaaag gagagtataa
    12301 acaatgatag acaatagatt acagaaacac attgatttgc tgattaaacg ctatcccact
    12361 cttgaagtaa tcaagcagga tattgttgac ggatacctga ttatggagga atgctattta
    12421 aatgatggca agctgctgat agcaggaaat ggcggatctg ctgctgattc cgagcatatt
    12481 gcgggtgagc tgatgaaaag ctttaagacg cctcgccctg ttagtaggga atttgcagat
    12541 aaattgattg cggttgatcc tgtaaagggt tctgaattag ctaagaatct tgaatatggt
    12601 ttgatggcga ttcctctcgt tgctcatgaa gcgctttcca ctgcgtatat taatgatgtt
    12661 gatggcctag gtgttttcgc acagcagttg tttggatttg gaagacctgg cgatgtattc
    12721 cttggtattt cgacatccgg caatagcaaa aatgtgataa atgcaactgt tgttgctaga
    12781 gctcttggta tgaaagtaat tggcttaact ggagccaaag gtggagaact tgcaagggta
    12841 gcagatgttt gtgttaaagc tcctgaaaca gaaacatata tgattcagga gtaccatttg
    12901 ccaatttacc actgttggtg tctaatgttg gaagataaat tttttgggaa tagataaaat
    12961 atctaagccc atattgaaag gataaaatta tgaatgtact atttataaca actcaatttc
    13021 catatcctct agataatggc ggaaaaattg gtgcgtacaa cggtatcagt gttttatcta
    13081 gagactacga tgtgacggta ttgtctttca ccgaagaacc gcagtatgtt gaagaaggtg
    13141 tcagtttttt tcgagagaaa tttaatagtg taaaatttga aaatcctgtg atacatgatg
    13201 tacacataag aaataatcca atgaaattgg tagaagcttt agcaataggg tattgtctac
    13261 gccaacctta tatagtttca aagttttatg attcaaaaat gctgcagtta atagatgaaa
    13321 aattttctaa caatgcatat tgggatatca tttttattga ctatctgaat atgcaaagtt
    13381 atggtcaata catacgggag aagtataaaa cacaatttgg taagtatatc ttaaaagacc
    13441 acaacataga atatgattta gtcctacagg aagctgaatc aagtcgaggt ttaaaaaaga
    13501 agttgcttca gttagagtat aagcgtactc gaaagtatga agaggccgca gtaaataggg
    13561 ccgattattg ctttagtgtg tgtgatgcaa atacggaagt actgaaaaag attaatgaca
    13621 acagttatac gatgcttcca acttatgaaa tgcttacagg ggtgaaaaaa aatatagaga
    13681 agaacacgat cctatatttg ggtaaccttt cttggaaatc caatatgcaa ggattagttt
    13741 ggtttttaga gtcaatttat ccaaatattc aacaaagaat tccggatgta aaaatcacaa
    13801 ttgtcggtag cgggccagtt ggaacagatt ttagtaaata ttcaggcgtg gattatcgtg
    13861 ggtatgtaaa agatatttca cacatttatg acgatcaagc ggtgctaatt gtacctttgt
    13921 tagaaggtag tggtataaga ataaaaatat tagaagcgtt caataatgaa attgcagttg
    13981 tatctacatt agttgggtgt gatacgattg gcgcaaaaga tggaagtgag ttatttatag
    14041 cagataacga aaaagatttt gcaacggctg tagttagact gcttgaagac atgaatttga
    14101 atgaaaaagt aagaaagaat gcaaaattat tcttaaaaga aaaatactcc ttaacggcta
    14161 gacaagatga gtttagtgcg ataattaaca gctaatatat atataagctt atctgatgat
    14221 gatttatagg aggaaatata tggagatggc tgagagaaag gaaaagaaac ttggaaataa
    14281 gaatatcata ttattttaga aaactcctgt tattttatgt ttgtgtgatt gttgcggcta
    14341 tgagttacca ccttacaggc aattccaatg tagcgtcatt aattgctgta gtaggagtag
    14401 tttatgctat tgtaaaggcg tgtaataacg agtatctggc tatatgggtt atgtttgtat
    14461 taggttctga tatatggggg atagtgccat atattaacat tggtagtggt gtgttgcatt
    14521 ggtcagattt taatgttata gtagcgatat ttctctgctt gagattcatc aaagttaaag
    14581 ctaggagtag atacgggatt gtctatagtg taatgcttat atttattttg attgcatgtg
    14641 tgcaatcgca ttcaatctat ggacaagatg tacatacaac gctcttaaca gctagagaat
    14701 tgctagttgt aatatccttt tggccgatag taaaaatagt atattcagaa agaataacta
    14761 aaaatgaatt cattgattta gtgtgtaaat tcacaagatg gacaatgtgt atatattggt
    14821 ttgaatggat tcttgttaat atgggattca atataacctt tttacagaca ggtgcacgct
    14881 ggggtactag aatctatata gatccgatat ttatcatttt atatttcttt ataaatctat
    14941 atgcggttat atataaaaga gagggctata atagtacaaa taaaagtata tggaattgca
    15001 tttttagttt actgacattt gttataatct cgcaaggcag aagtggtata ttatatgtag
    15061 taataacctc ggttattatg cttttaattt cgcttaaacc atccaagatt attagatttg
    15121 gtatattagg aattgcctta attgcatgtc tagtgtctgt gacccaaatt agagaggtcg
    15181 ttatatcttc gtttgtagag tctcagagca gtgacacagg taatatcgca tatagaattg
    15241 ctgaacaaga ttattttgaa aataaattag aaggtcatga actatttgga gttggtatac
    15301 caaacaatca tgatgccaga gctgtagaat attcaggcaa aacaatagat tttgagtcta
    15361 aaaaatataa tccctattat cttgaggact taggcgcttt tgaaattcgt tatagatttg
    15421 gtataattgc atatgcgtta tatatagttg ctttagctat aagtattata gatgccggat
    15481 ttcgaagaga caaatcggtc gccgcatttg cgggtatggc attcatggtg tttatggcgc
    15541 ttaattttaa tttgctagcg tatattacag caagaccgtt cggatttatg atttctttaa
    15601 ttttgataga aatatcggca ttcaatgatg aattcatata tattgaatag gtaagggaga
    15661 gcacagatga atttagatcg attaaagaaa atagcaaata tgatttcacc aatcataaaa
    15721 gtgataaatg cgccgttagc gtattttagt gggaaatcag attatatgga gaagggaata
    15781 ttgtggccta ctgtaacaac ctactccaat aacagtagaa aagtgattca atatacaact
    15841 ttacctaaaa acgtagacaa catggctcaa atgcaatggg ctggggaaag ttttgaggac
    15901 atatgtatag ttcttcaagg tccagtatta gaagacggtg attttacact aaataccgtt
    15961 aaaatgtata ataaatacta tcctaaagta aaacttgtag tgtctacttg gataggatta
    16021 tctgaagaga cagaatgcaa gttgcgtgaa gctggtgcag atgttgtatt atgcaagaaa
    16081 cctgaaaaaa caggtgcgta caatattaat ctacaactta cttctgcata cgaaggcgta
    16141 aaaatggcgc aaaaactggg gtgtagttat gcgctgaaaa cgcgaactga tcaaagacta
    16201 tatgcaaatg atgtactaaa gtatttccaa acattattga atatttttcc atcttcggac
    16261 tgtaaagtag tgaatcagcg attaatattt acgacttatg gaaaatcatt tagatatctt
    16321 ccgtttaatt tatgtgattt tttggtatac ggagaaacta gtgaattatt aaaattatat
    16381 ggtattcaaa gagataaccg agcatcagac tttgggaaaa ttatttatac tgaggaaaaa
    16441 gagtttaata aaaagatatt tacactacta gaaggaaaac aaggtgtatc tccatatgat
    16501 gtttttccag attttgatgc actatataaa aaatatatgt ttgcagaata ctatattgtg
    16561 tataattatt tcctggaaaa tattgcaagt aatgaatctt atggtgactt aatggatgcc
    16621 tattatagtt atttaaagaa atatgcagtt gttgctgatt cagaaaaatt gttactatat
    16681 tggccgaaat atgttcaata taatgttaag ttcgaaaatg aacttgattt ctatgcgaag
    16741 ttggattcaa aaaaatggat ggatatttat gctaattata caccttttag tcagtgatta
    16801 tatggaaagg atgaggtgaa taatgaaaat cggaatagtg actattgtta atggggcaag
    16861 ttttggtaac agattacaaa attatgcgac tcaaaaagtg ttggaaaata acggctatac
    16921 agttgagaca attaataatt gttttgacaa agaaagtacc ctatccattg ttatcaaaaa
    16981 cgctatttat acattattta agtttatacc gcatttcaaa aagtcaaaaa gtatctggaa
    17041 aagaatgtat acattttatc aatgggacaa gcagtatata gattattctc atcgtaaaat
    17101 tgatgcatct aaaaaaaaca gctttgtgag tataaagaat gattatgact atttcttggt
    17161 tggtagcgat caaatttgga atccaaaata tgcagccaat aagggatttg aacttttatc
    17221 atttgttcca aatgaaaaaa gagtttcatt atcaaccagt ttgggagttc catctatacc
    17281 aagtgattta gaaaaattat atgtgacaga gtggaataag tttaaatcaa tatcggtacg
    17341 tgaaaatcaa gcggcaaaaa taattgagga cttgacaggc acaactgcgg ctgttcacat
    17401 tgacccaact ttaatgttgg agcgttcgga atgggaagcc tttcaaaaaa aaccagacaa
    17461 tattgatgaa aattacatct tgtcgttttt cttaactaat ccgcctaagg atactgttga
    17521 tgtattagat aaggtcgcta aagatttgaa aataggtgtt ctcaccttag atgcgtcttg
    17581 ggaatatttt caagatatta ctccgaatca ttttgtttat ttgatttcac atgcaagaat
    17641 gatttataca gattcattcc actgcacagt tttttcattg ctatttggaa aaccggttgt
    17701 ggtatttgac cgttttgata gtgaaaaaat gaattctagg ttaagtacat tgttaaataa
    17761 agtaaataaa gcacattttt gggtaggaaa aaaagctgat gaagcaatga ttcgtgcaat
    17821 agcatctgaa cctgaatatg acatagataa gctgatggta tcagagaggg aatgtgtaaa
    17881 agcttatctt aaagagtatt tacagtaaaa ttttgaaatg ggatgaaaat atggagcatt
    17941 taagtgattg ttttggtaaa atgaagattg ttacgacttc atgcgcaaga gaatatttta
    18001 aggatgattt ggataaatca gagtattcat gttttgttga ttctcgagca gctatgtttt
    18061 tcgcaatggg acaagcttta gctaaaagaa ggaatgtagt tgtaatgctt gctgatgaat
    18121 tgacatcgtg ttatacggca ctaacagaat gtgcatttca acaagttgat ttaattgtgt
    18181 ttgcttttca gacagtcaga catgaaattg atttagcatc tttgaagaat tgtggttgca
    18241 atctaattaa ctgtagcgcc caagacgata ttgatagagt tgtgtccaac actaaggggt
    18301 taaatcagac aacagtaatt aaaatcaata tgaattgtga gtcggataaa gatcatatat
    18361 gtgagtatat agacctgcca gacatacctg tttttttcca cggtagctta tactcacctg
    18421 caagtaaaaa gaaatatgag cagtatggac aggtatcgaa gtatttaggc tatctcgtgg
    18481 ggggaaaaga tgcaatactc ataatttctc acaatgagtt tttaaacgat atcagtgtat
    18541 ggattaatta ttattctttt ggagaaattc aacccaaaat tattatattt gacagtccga
    18601 atgactatca atataaatgg ctgtgtgact tagaatgcag tgtagctcat tcaaccaacc
    18661 gatttttgtc tgaggattta gccttattgc aaaataacgg aatttccatt gtgttaagag
    18721 gtgataatta tgatatcgtc agttaaaaat gttcaaattt tagtatcttt attaaaacag
    18781 cataatatta aagatatagt tatctcgcca ggtagtagag attttcaatt ggtgcatagt
    18841 gtagaaacag acagtttttt tagaacctat acggttgtag atgagcgcag tgctgccttt
    18901 tttgctaatg gactttctat ggcgattgat aagcccgtgt gtgtatgttg tacttcttca
    18961 actgcctctt caaattatat ggcggcagct aaagatgctt ttgctaatgg catccaactt
    19021 gtacttctta ctgctgatag agattaccgc cgcttatatc agatggaaga tcagatgatt
    19081 gatcaggtag atatgtatgg ggcttatgtg cgttctaacg ttgatattcc tattgttaag
    19141 gattctgatg atgaatggta tgctaccaga aaaataaatg aagcaatatt ggagttaaat
    19201 catggcgtta agggtcccgt gcagattaat tatcaattaa tggatttaag tgcgccgttt
    19261 gttgagacca tgccagagta tcgtaaaatt acaagatatc aagaggatga tttactgtca
    19321 tcagtagaga tttttaaaca gaaactatta tcaaaaaaga gaataatggt tttatgtgga
    19381 cagcaggaag aaaataattt aagtgcctta ttggaagagt tctttattaa atataataca
    19441 attataatca aggataacta ttctaatata cacggtgaac actttattaa gactgttcta
    19501 gtaacagaaa gaatgagtgt aaatgcattt attgattatt gcccagattt ggtaataact
    19561 attggtaaac atgtatggtc ttttgtgaaa tatactctta gagataaaaa gcttaaattt
    19621 gagcattggc ggatatctga ggatggtaag attgttgatc cgttcaacaa gctaacatct
    19681 gtctttcagt gctcagcgga attttttatg gagactgtca ctgctggtgt gaatagcaat
    19741 aataatcttg agtattataa tctatggaag acaagattat caaaagtttg ctatccagag
    19801 ttagtctata gcaattttta tgcaatttca gaactagtaa aaaaaattcc agatagtgca
    19861 ttagttcatt ctagtatttt aaatgcggct agattgtatg actttgtatc tgatgataaa
    19921 gcattactca gttttgctaa tttaggggct gatggtattg atggttgttt accaacattt
    19981 ttaggtcagg cagaagcaga taaaactcga cctgcgtatt taatttcagg agacttgagt
    20041 ttcttttatg ctatgaatag tttatgtggt gacattccag ataatgcaca tattttcctt
    20101 attaacaatc attctggaag tgaattccat acaaattttg gtaagtttta caacggatca
    20161 ttaagtgttg ataagcatat agctgcagga catatttcaa acgcaaagga ttgggcatta
    20221 gaaaataata taaaatacat tactgcggat tctaaggaaa gtctcaaatc ggggttggat
    20281 gtatttatta atacatttga cagtcctgtt ttatttgagg tctttacaga tccggatacg
    20341 gatacgtctg ttctggaatc tttttatagt ataaataagg taatcacacc aaaaatgtat
    20401 tttagaaagg cgttagatat tataaaaaag catttacaca ttaagtagat gtttattgcg
    20461 aggtgaaaca aatatggcaa taaaatctta tattaaacgg ttattgcttt atatccgtca
    20521 tggagatccc aaaataaatt tagatgtgag ttatttatct gaaggtgcaa tgcttgctgg
    20581 taagactgtg ataattacgg gtggtgcaaa aggacttggt tttgcaattg caaaatcatt
    20641 tatagctcaa ggcgcaagcg ttattattac aggaagagac atggattcgt tgaataatgc
    20701 taaatgtcag cttggagata tgtgttctat cagggcgttt gatataactg atgctaaaat
    20761 gtatcgaacg ttttttgaag atgcatacga gacctttgga cgtattgata tactgcttaa
    20821 taatgctggg atctcgttac acgaagatgg atttatgagt gttactgaga aaacttggga
    20881 taagcaaatg gatacaaatt tgaaaggtgt ttatttcttt acacaggaat ttattaagtt
    20941 tgttaaagaa aagaatcaaa tgcaagcaaa tattattatg atgtcctcag aaagaggctt
    21001 gtgtggtgat agtattccgt atggattatc aaaggctgca attaactctt tagttgtagg
    21061 cttgtctaag aaatatattt ctgagggaat tagggttaat ggtattgctc ctggagtaac
    21121 tgcaaccgct atgactggta tttctgaaaa gggtaatttg tataatcctg caacgatcgg
    21181 ttatagatat tttctcccag aagaagttgc tcaagttgct ttgtttttgg caagtagtct
    21241 ttcaaactgt atcagtggtg aaatcatagc ctgtgaccag gggcaatatt taagtcgaaa
    21301 ttgggggtaa taacttggga atattattaa aaaaatataa tagccttagt gagcctgcaa
    21361 aagcatctat ttggtttaca ctttgtaatg tgttgcaaaa aggaattcta tttttgacta
    21421 cacctatttt tacaagaatg ctttcaactg cagaatatgg taagtatacg atttttatat
    21481 cgtggtattc tattatagca attttcacaa cgttgaattt atctgcaggt gtctataata
    21541 aaggactaat taaatacgag aataaatatg cattaacctc gtcattttta ggattatcgt
    21601 catttatttc cctttgtgca ttgatgctat accttccatt tagaacggtt ataaatgggc
    21661 tactggattt atcgacggag tttgtcatat tgattcttat tgaatcaata tttgagccgg
    21721 cttttttgct ttggtcagtt aaggaacgat ttgattacaa gtatcaaaaa ctagtactca
    21781 tcacagttct tatggctgtt ttaaatccag gtctcggtat tatattaatc ttatcatttg
    21841 gggagtatgc tatttggaga gtacgagctt atgtcgtggt aaatgttgta gtggggatgt
    21901 ttattggcat aggaatactg gctaagggta agaaattatt tgataaagag tactggacat
    21961 atgcgctcag atttaatttg ccattaatac cacattattt atcaatgaca ttgctgaatc
    22021 aggttgatcg ccttatgata aatagtatgg ttggagctag cgaggctgcg atttatagta
    22081 tcgcttacac tatatctagt atgatgaata tcataacaac agctataaac ggttctttta
    22141 ttccttttac atacaaagca attaaagatg gcgtgtatga aaaaattaaa tccgttgcta
    22201 atcaactatt agtgttgatt tttgtcttgt gttcgtttac tatgctgttc gggccagaat
    22261 tgatttgggt tgtcggagga gaaaaatata tggatgctgt ttggattatt cctccagttg
    22321 cggcatcagt atttttcatg tttttatatc cgctttttgg caatattgaa ttttactatg
    22381 aaaagacaaa ctacgtaatg tttgcatctt gtgtgggctc tatcgcaaaa attatttcaa
    22441 actatgttag tattccccgt tttggatata tttcggctgg ttacacgaca ttgatttgct
    22501 atatgttgtt ttcctttgcc cactacatgt tttataaaaa aattcttaga gaaaatggta
    22561 taaaagaaga tatgtataat attaaaaata ttatatttct ttctgtctta atgattgtgt
    22621 taactattgg tatgacaata ttatactttt ctacaattct aagatatagt attattattg
    22681 gattagttat tgtggctttt cttaaaagga cgcaaataat gaaaatcctt aaaaatataa
    22741 aaaattaaca agcaaatctt gggaatggaa cggaggcacg gtgaaatgag attattgatt
    22801 ccatctgcta agattgtacc ggaagaactt caccatcttg gaaaacttcc tgcaattatc
    22861 tatccgatta atcaaaaaat tgtatttgat tatttatatg atcaatataa agatgtatgt
    22921 tctgctatcg atattgcctg ttacgaaaag atggataagg tagcaagacg attagataag
    22981 tatattaaat ctaaaacagt aaatattatt cagcttaaag agttagggga tcttggaaga
    23041 actatatatg attctctaat aggatgtgac gagcctgtta ttattaattt tgctgatacc
    23101 attatcaatg ataatatata ttccttggaa tgtgacagct ttttctatgc tgaagactat
    23161 tatagtaata cttggacatt ctttgaagaa aaagacggag atattatttc tgttttagat
    23221 aagaacgagt taaaagaaga tgatggaaag aagcacaaac tgttttctgg tgtatttcaa
    23281 attatggatg cccagtattt tagagagtgt ttgcgtaaag ctttgatgtc aaatgtagta
    23341 aatgtgaata gtttttatca agctttacaa gagtatagca aacgatatga atttctctct
    23401 attaaaacaa ataattggtt tgacattgga catgcagata aatattataa ttccaaattg
    23461 gaagttaagg caagagaatt taaccacatt tcaattgata aagatcgtag catcctgaga
    23521 aaaattagtg aagatgttga aaaatttatc ggagaaatta agtggtatct taagttgcca
    23581 gcacaggtag aatatgtgag acctagaata ttcgaatatt ctacttcgta tattaatcca
    23641 tatgtaagta tggaatacta ttcgtatcat actgttcacg agttatttct ctatagtgac
    23701 ttaacaaaaa aacaatggat agatatcttt aatagaatac gatttgtatg ctcagacttt
    23761 aagagatact ctgtttcagg ggataatatt caaaagtcat tgaaagatat gtatctcgat
    23821 aaaacatttc agagattcaa taagctcaga aaggaccccc ggttcacaga attcttttct
    23881 tctgatattc aaataaatgg agtcagatat aaatctttgg accagataga agctttattg
    23941 agcgtaagtg ttccaagaga attgtttgac attacgcaat ttaatattat tcatggtgac
    24001 ttatgctttg ccaatattat ggtagataac acattttcgt tcattaaagt catagatccg
    24061 cgaggtaagt ttggagattt tgatatttat ggtgattata gatatgaact ggcaaaattg
    24121 tttcatagtg ttgatggaaa atatgacttt ataattaagg acttgtttac aataaaatat
    24181 gatccaaaga aggcaatcat agactatatt gttcaagatc gtaaacgaga ttatgattta
    24241 tatgaagtat tttactctgt cttcaaagat gaaataggtt ctgatttgaa aaaaattgaa
    24301 cttattgagg ctttgctgtt tttaagtatg attcctttgc atggagaaag cttaaaccat
    24361 cagatggcta tgttagcaac tggtttggaa attttaggac gagttgtccc ggatatttat
    24421 tgttaatgct ttgagctatt gtttttctat ttgatcagtg taaagccggg catataaatt
    24481 gcctggctaa aataaaggag atgtcttagt tatatgttta aagattacgc atttgttttt
    24541 gatattgatg gaactttgtg ccccatcaaa aagaaagatg agaaatatga agatttagtt
    24601 ccgtatgcta atatggtgga gaagttgcga tactataagg agaacggagc aaagattaca
    24661 ctgttcacat ctcgcaatat gaattcttat catggtaatt taggtgtgat caatgcaaat
    24721 actgcaaaaa tcttgttggc ttggctagat aagtgggaga ttccgtatga tgaaattctt
    24781 tatggaaagc cttggccagg ccataaaggg ttttatgttg atgatcgcac agttcgtccg
    24841 gatgaatttt tatcgtgtac cctggatcag ctcgatgaga tttgcaaaaa atccaaattg
    24901 aaatctgagt aaaggagact ttataaagtg aataagatga cggttattat tacaatggct
    24961 ggtcttggca gtcgctttcg taaagttggc tacactgtgc ccaaatttat gattgaagca
    25021 aaaggtaaaa ccttatttga ttggtcctta gacagcttgc ttgattataa ttcacatgta
    25081 gaaaagtatg tttttgttgt gcgtaaggaa gatgatgcta ctgtttttat caaagaacat
    25141 tgcagtctgt atggaattga aaatgtcgag gtagttgaaa ttgactatat gactgatgga
    25201 caagccacta catgtatgct tgcaattcct tattgcgcac ctgataatgc aattatggtt
    25261 tataacatag atacatatgt tgagccaggt gagatgaaat acgttgatat ttctggagaa
    25321 ggacatattc cgtgtttcca tgcggacggt gatcattgga gttttgccaa gttgaacgaa
    25381 tatggtgatg tagtagaagt aagagaaaaa gttagaattt ctaacaattg tactttaggt
    25441 gcatattatt tttcttctgc aaaattatat gcatcactct acgaagaata ttatgcagat
    25501 gaaaggcatc tggaaaagaa tgagaaatat attgcgccgc tatataatta tatgatagag
    25561 aagggcatga aggtaaccat tagtatagta gataaatcaa aagttcacgt actcggtact
    25621 ccagaagagc tcgatgtgtt cttaaatgaa tagggaaaat ataatcatag aaaatgttaa
    25681 ttataaagct gcgtgtgtgg gggagtacta ttcgatagat attctaaaaa tactaatggc
    25741 tattttagtt gttgttcgtc atttaggtca aaactattta gctccagatt aagcatttag
    25801 tattggtatt gttgcaggac tgagtacggt tgccgttcct acttttttca tcatcagttc
    25861 ctttttgttg tgtagtggtg aagttacatc cgctaaatta tctaaacaaa tctacagagt
    25921 acttaaaatt tacattattt ggtctatatt atatattcca ttagtattaa agaattgggt
    25981 acagtcagat tttagctgga aaacagatgt attattgtat atcagagatt ttctgtttat
    26041 tggtagttac tatcacctgt ggttcttgcc tgcactggct tttgctctat ggttagtacg
    26101 caaaagccag gtttctaaaa taaagtttct cagtggtttg ttgctatgcg tagtaggttt
    26161 agcatttgaa tcttattggt ttatattatc tgggaatgat tccatcgagt atattagata
    26221 ttgttataaa agcgtgtttg taacaactcg taatggatta tttataggtg taccatgcgt
    26281 cattattggg caacacttag ccttccacaa aaacactata cttaataagg tctttaaata
    26341 ccgtaatttt atcttatgtg ctgttttagc tataggatgc ttattagttg gtgaaagttt
    26401 catcataaat caaatagctt tgcgagaagt caataatttg ttaatatttt ccattccatt
    26461 agcactggta gttgtatcag tatcactgag cctaaagata gtacatttat aaaaataaca
    26521 gtacatctgc gaagaattag tacgttatta ttttgtttac atccgtatat aatagctgct
    26581 ttaaatttta ttttcccaaa attggggatt acaaattcat taatagaaat gacttgtgga
    26641 atgataataa ttttaatttc tacagttttt gtgtatgcgt gtagtgtgaa atttaccttg
    26701 ctgaaaaaat tatattagat tagtaactgg tacatgtaaa tttgttgaaa ttatagcagc
    26761 atagagatag gaattctgtt gagttttatt ttcgctggcc gaggttattc atgttagagt
    26821 gggtacctcc ttttacgaaa ccttcttgat ggtactcatt tagcgcatga tgaaaggaga
    26881 gtttatgaag aaaatcatat cttctatttt ggttaatgtg ttatctgcat tgtatcaaat
    26941 atttgggttt cgattttaat tgcagttttg gctatgtttt tatacttgtt tgcgatggct
    27001 gaggagaaat caggattagg tttgaaaaaa tcttttcttg tctggattcg gtatttcaga
    27061 aaatcaagct catttagaaa aatgtttttg cttgtgtttt ttacaaatat gattcttttt
    27121 agaacactga tggatagata tgtttggcta aatcctttgt ctaatgtgtt tggtagttgg
    27181 tggatttact ctgtgaatga aacgacaggg gagattagat taactacaga atgttttgaa
    27241 aatgttattc tgtttattcc atttataatt ctagtaatgt ggtataaggc ttcagaaaaa
    27301 gattttggaa aaatttatca gagattataa aatttgtttt tttatgttcg tgtcttatag
    27361 agtttttgca gttattttta cacatagaga cattccaatt gtcagattta ttttataata
    27421 ctttgggtgg cggcattagt ggggttatat attatttgag ctgatatatt catcctaacc
    27481 ttaaaaataa atgagcagaa ttttaaaaga ttggagagat tctatggatc ataatgcaaa
    27541 ttattatcat tggcttacaa atgccaatgc agaaattgta gaggaactgc ggtcatattc
    27601 cgagaaggac attgaggact ccttctataa aaatctgtcc tttggtaccg gtggtctgcg
    27661 tggcaccatt ggtgcaggca ctaatcgtat gaacgtacac accgtaggta aggcaagcca
    27721 gggactgtca gactatctga ataagaccta tgaaacccct tctgtcgtcg tgggctatga
    27781 ttcccgaatc aagtccgatg tatttgcaaa ggttgccgcg gacatctttg ctgcaaacgg
    27841 tattcaggtg catctgtggc cggagctgct gcctgtgcct accgtatcct ttgctatccg
    27901 ttatctgaag gcttctgccg gtgttatgat caccgcatcc cataatcctt ccaagtataa
    27961 cggatataag gtctatggcg caggcggctg ccagatcacc accgaggctg ccgctgagat
    28021 tctggctgaa attgaaaagc tggatatttt tgcagatgtg aaaatgggcg gcgacgcttc
    28081 cagaatcgct tctatccagc cagaggttct gactgctttc attgaagaag taaagggcca
    28141 gtcggttctg tttggcgaag aagtggacaa gaatgttgct atcgtgtatt ctcctttgaa
    28201 tggtaccggt ctggtgcctg ttacccgtac tctggcagaa atgggctaca gcaatgtgac
    28261 cgttgtcgaa gagcagcgtc tgccagacgg taatttcccg acctgtcctt atccgaatcc
    28321 ggaaattaat gaagctatgt ctctgggcat ggagtatgcc aagaagtata atgctgatct
    28381 gctgctggct accgaccctg actgcgaccg tgtgggtatc gccgtgaaga atgcagaagg
    28441 ggattatgtc ctgctgtccg gtaacgaaac tggtctgttg cttctggact acatatgctc
    28501 tcagagaatt aagcacggca agatgcccac tgaccctgtg atggtcaaga ccatcgtgac
    28561 tatggatctg ggcgagcgga tcgcttccaa ctatggcgtg cgtactgtcg atgtgttgac
    28621 cggcttcaag ttcatcggcg aacagattgg tatgctggaa aaggcaggca aggtggacag
    28681 ctatattttc ggctttgagg aatcctacgg ctatctatcc ggcagctatg tccgtgacaa
    28741 ggatggtgtc aacgccgctt atctgatctg cgagatgttc tcttactaca agactcaggg
    28801 tatcagtctg tttgataagc tgaacgagat ttatgctaag tatggctact gtttgaacac
    28861 cctgcattcc tttgagtttg agggtgcggc aggttttacc aagatgcaga aaattatggt
    28921 tgaattccat aaaggtcttg atatgattgg aggtaagaag gtcattgaaa ccttggatta
    28981 cagcacggga ctgaatggcc tgccgaagtc tgatgttctc aaatatctgc tggagggcaa
    29041 ctgctctgta gtggttcggc cttccggcac tgagccgaag ctgaagacct atatcagcgt
    29101 tagcgcagaa agcaaggaag ctgccgaagt aatggaagct gttatggctg ctgaactggc
    29161 tgaaatgttt aagtaatact atgaaaaaga tctgagtgtc aatgtccgaa gtagcaacat
    29221 ctatgtttaa taaaaatttc ctgctttacg gttctgttta cataattgag gtaaaggggc
    29281 cgactgtgtg gatcgaaaag gcaaagaagt gttaacagag acacagcagc ctgatgaagc
    29341 accgatcaaa gcagtaaggg agaaataaga gatattagag ttttaataat gtattcagca
    29401 atagagatga aaggagtaga atatgaataa aactattgaa ataataaaat gagggggaaa
    29461 gaaataaacg tgatattatt agttttgaga aggcgttttc aatattcgct attgtattga
    29521 tgtactattt tcagcaatcg tatttgccag caatactgaa caaagcaata tctattggtg
    29581 atacaggagt gcatatattc ttcttttgct caggttttgg gctatatctg tcatatttaa
    29641 aaaagcctat tacattgggt gaatttttac agaaacgatt tatcaagatt tatattccgt
    29701 atattatcgt aattacggta tcagtgttac taccttatat gacacaagat ttaaatgctg
    29761 caaaagtata tttgtctcat gttttgttat ttaaaatttt tctaccagta tatgaggagt
    29821 cactgggtcc ctttggttta tttcgacaat tattcagttc tatttcttat tcataccaat
    29881 tgtaaaacta tagagaaaaa taggaatgaa atgattgctt gttgcaagct gagttattag
    29941 tatctgggct attatgatgt ttcatacagg atatggaagc atacgagttc ttgggagctg
    30001 ctttgcgcaa tatatttggg aatttacttt cggcatgttt ggttgcagag tatttagtga
    30061 aaagaaaaat agtaagattt aataatatat tcgtgattat ggcgtccatt gttggaattg
    30121 gttttgctgg tatatcgaaa attattggtg gactgatgga gtctattaat gatatttttg
    30181 cattcttcgg ttacggtgca attgcaattt taatgtatca agttattcca tttagaaaga
    30241 taatgcctag gatttcaaga tactcatatg atatatatct actccatatt cttgtattta
    30301 gtacgattca tcaaattatc cctaacttgg ttttggcggc atttgtttcc attcctataa
    30361 cgttggtgtt gtcatattat tatagtatta tgttatatag acttaaatta aaatgatagc
    30421 ataattgtcg cctctaccgg gcggttgcca tcctgattaa cagcctccac gcggcggatg
    30481 gtgggcactt aggtagttcg taacctagtg gtagatggtt ggtaaaaagg agataaaact
    30541 aaatgatt
//
LOCUS       DAFBSV010000024        30111 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.025, whole genome shotgun sequence.
ACCESSION   DAFBSV010000024 DAFBSV010000000
VERSION     DAFBSV010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30111
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.025"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(203..1654)
                     /gene="cls"
                     /locus_tag="LLB18_001055"
     CDS             complement(203..1654)
                     /gene="cls"
                     /locus_tag="LLB18_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBK5244069.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            1995..4661
                     /locus_tag="LLB18_001056"
     CDS             1995..4661
                     /locus_tag="LLB18_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBK5244070.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            5025..5777
                     /locus_tag="LLB18_001057"
     CDS             5025..5777
                     /locus_tag="LLB18_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBK5244071.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(5799..6953)
                     /locus_tag="LLB18_001058"
     CDS             complement(5799..6953)
                     /locus_tag="LLB18_001058"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HBK5244072.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            7138..9579
                     /locus_tag="LLB18_001059"
     CDS             7138..9579
                     /locus_tag="LLB18_001059"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HBK5244073.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(9909..10613)
                     /locus_tag="LLB18_001060"
     CDS             complement(9909..10613)
                     /locus_tag="LLB18_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244074.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(10800..11045)
                     /locus_tag="LLB18_001061"
     CDS             complement(10800..11045)
                     /locus_tag="LLB18_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244075.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(11062..11913)
                     /locus_tag="LLB18_001062"
     CDS             complement(11062..11913)
                     /locus_tag="LLB18_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBK5244076.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            12079..13083
                     /locus_tag="LLB18_001063"
     CDS             12079..13083
                     /locus_tag="LLB18_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBK5244077.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(13324..13680)
                     /locus_tag="LLB18_001064"
     CDS             complement(13324..13680)
                     /locus_tag="LLB18_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBK5244078.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            14048..15235
                     /gene="tuf"
                     /locus_tag="LLB18_001065"
     CDS             14048..15235
                     /gene="tuf"
                     /locus_tag="LLB18_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBK5244079.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(15423..18014)
                     /gene="mprF"
                     /locus_tag="LLB18_001066"
     CDS             complement(15423..18014)
                     /gene="mprF"
                     /locus_tag="LLB18_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBK5244080.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(18040..18801)
                     /locus_tag="LLB18_001067"
     CDS             complement(18040..18801)
                     /locus_tag="LLB18_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK5244081.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            19079..19600
                     /locus_tag="LLB18_001068"
     CDS             19079..19600
                     /locus_tag="LLB18_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBK5244082.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            19659..20519
                     /locus_tag="LLB18_001069"
     CDS             19659..20519
                     /locus_tag="LLB18_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HBK5244083.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            20704..23019
                     /locus_tag="LLB18_001070"
     CDS             20704..23019
                     /locus_tag="LLB18_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBK5244084.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            23201..25042
                     /locus_tag="LLB18_001071"
     CDS             23201..25042
                     /locus_tag="LLB18_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBK5244085.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            25066..26175
                     /gene="rpoD"
                     /locus_tag="LLB18_001072"
     CDS             25066..26175
                     /gene="rpoD"
                     /locus_tag="LLB18_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBK5244086.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            26395..28494
                     /locus_tag="LLB18_001073"
     CDS             26395..28494
                     /locus_tag="LLB18_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBK5244087.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            28690..29553
                     /locus_tag="LLB18_001074"
     CDS             28690..29553
                     /locus_tag="LLB18_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBK5244088.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            29658..>30111
                     /locus_tag="LLB18_001075"
     CDS             29658..>30111
                     /locus_tag="LLB18_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBK5244089.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKE"
BASE COUNT        10008 a         5316 c         6262 g         8525 t
ORIGIN      
        1 gaaagaggtc gtgagcctgc cgtccagctc cgagtcacaa ggaacaagtt caaaaaacag
       61 cttctcatgt ttgttgaata ttgtgacttg tgaccgagga gttggcagga gaacaccgtt
      121 tgttcggaag aagggactgt gacaagattt ttgtcacagt ccctttaatc ttagtatatt
      181 tttctctact tgaataaaaa aattatagga ttggagaaaa taatcgagaa atttgttgct
      241 tgaataatag ccagttagac atttccttga ctgtttcagt tgtcatggat gaacaatgtg
      301 tctcatcttc tttgaactga gtagcaagtt cttctaaaaa ctcaggatcg taaatgacag
      361 cacttgtttc aaaattcaat cggtagctac gaatatcttg atttgctgaa cctaccatgc
      421 agatttcatc atccattatc aatgtttttg catggaggaa gccgttctca tagacaagga
      481 tttgtacatt ttccttgatc agctgccgag cataatattg tgttgctcga taaataaaag
      541 gatgatccgg tttgttggga atcatgattt tcacatctac accagaggca gttgcgattt
      601 ttaaagcagc aatgacactt tcatcaggaa caaggtaagg tgtctgtatc caaacacgtt
      661 ttttagcaga agtaatcaat ttgataaatg aaagcttgat ttgttccctt tcgttattcg
      721 gtccgcttga aacaagctgg atggatgtat cagcaagctt agattcatct cgatctgctt
      781 ttttaaagaa ataattcaaa tgatagccga cctttttttc ttcaggtacc gagacgttcc
      841 agtctgttaa gaagcgaagc tggagcaaag aagaagcggc accgaaaatc cgtatatgcg
      901 tatcgcgcca atagccgaat ttttttgttg tatttacata ttgattggca atattgaaac
      961 caccggtata actaatcttt ccatcgatca caacgatttt tcggtgatca tggtaattca
     1021 atcggaaacg aagtaatgcc ctttgtgagg taacaaatgt atggacatgt ccaccatttt
     1081 tgattagacg attgaaatct tttgcttttg tgccatgaga gccaaatgca tcatataata
     1141 ttcgaacttc cacgccttct gcggcttttt cttctaaaac atgtaagact tgctggccga
     1201 tattatctgt cacaaatgcg taatattcga tatggatcga atgtttggct ttttttagat
     1261 cttgaagcag tgaatccaat ttctcttgtc cgtctgtgag aagagtgaca gaattcattc
     1321 ttgtcagcgg catacgattt aatgaagaga agaagtcaac aaattgctgt ttgtctttat
     1381 cgcccatgtc aggatcgtaa tgttcaatgg tatctcctct aaaagactga aagttttcta
     1441 attctttcaa gtcactttgt cggagataga attttttctt atccgttaat ccacgtccga
     1501 aaaataaata taatacaaag cccaccccag gaagggcaaa caatactaag agccatgccc
     1561 aaatggctgc tacatctcgg ggtttgatca aaatagccac caaagcaata agtgcattta
     1621 atagataaag ggcggttata atactagata ccacaaaaat gttcctcctt acatacaata
     1681 acattagtat agcatgatag aagaaagaag cctaccaagg tgaatatact tttcactcct
     1741 ttcatgaaaa tgtaggtaaa tcgggctaaa gtagttgctt tttgtaggtt aataaggtag
     1801 gatattagta cagttgaata tctccttagg ggagtaaccg gcaacgtttg ttgcgataat
     1861 atcaacagta agttaaccaa atggttttct ggtattgtat gaaatggtga gacctaagac
     1921 aaatgcgtat ttgtcttagg tctctttttt ttcagacagg actagggcca agatcaaaaa
     1981 atgggggatg aaatttggaa aacaaggaac aagcacaaca agcggtctat aaagaaacga
     2041 tcgactcgtt gatgcagcaa acgcagagct caaccgatgg attgagcacc acgcaagcga
     2101 aggaaaaatt agaaagagat ggcttgaacc agctaaaaga aaagccgaag aagccaactt
     2161 ggaaattgtt cttagaaact ttcaaagatg caatggttat cgtattgctg attgtcgcac
     2221 tgattcagat ggtcatgggt gactacatcg aattcttagt tatttttgca gtattgatgt
     2281 tgaattctat aatcagtgtt gtccaaacaa aaaaagcaga aggttcttta gaagcgttga
     2341 aaaacctttc agcgcccgat gctcgagtga ttcgtgatgg taaggaaaaa acgattccgg
     2401 caaacgaact tgtggtagga gatatcgtgt tgttagacgc aggcgattat gtacctgctg
     2461 atggacgttt actagatgcg ggatcattaa aagtagatga aggtatgctg acaggagagt
     2521 cgacttctgc agaaaaagaa gtaacggata tcacaagtac ggtaccaatc ggagatcgta
     2581 caaatatggt attcagtgga acgatcgtaa cttacggacg cggtaaattc ttagtgactt
     2641 caactgggaa taatacggag atcggacaag ttgctggcct tttggaatca acaactgagc
     2701 aagtcactcc gttacaacga ggtctggata aattcagtaa aaaactaagt ttggctattt
     2761 tggcattgtc tttattgatt ttaggtatcc aactgtttcg tatttatctt ggagaaggta
     2821 caggagatat gactgcagat atcgtcagcg cagtgatgtt tgccgtagcc gtagccgtag
     2881 ctgctattcc agaagcatta cagtctatcg taacaatcgt gttatctttg ggaacgaata
     2941 aaatggcaaa acgtcatgcc attattcgga agcttccagc agttgaaaca cttggttcga
     3001 caagtatcat ctgtacagat aagactggta cattgacaca aaacaaaatg acagttgttg
     3061 actacttttt aggtaatggc gatactgggg atttcacaaa tgacccttca aaatggacag
     3121 ctgacgaacg tcgcttgatc gaaatcagtg ttttagcgaa tgatgcatcg atcagtgaag
     3181 acggtactaa attgggcgac cctacggaag tagcgtttat cgactttagt gaaaaattaa
     3241 accagcctta tcaggaaatc cgaaacaact acccaagaca agcagaactt ccttttgact
     3301 cagatcgaaa attaatgtct actggacaca caattgataa caaaaattac ttgtttgtta
     3361 aaggcggacc agatatcgtc ttccaacgca gtaaaaaagt attgctaaat ggtgaagtcg
     3421 ttccgatgac ggatgaattg atgaaaaaat tccaagagca aaatgaagct ttttcaacac
     3481 gcgcattacg tgtactagct tttgcttacc gtccacttga taattttgat ttatcatttg
     3541 aagatgaaga cgatttgatc cttgttggtt tgcttgctat gatcgatcct ccacgtgctg
     3601 aagtgactca ggcggtaaca gaagcaagaa gtgcaggaat caaaacaatc atgattactg
     3661 gtgaccacaa aacaacagct gttgctatcg caaaacaaat cgggattttt gaagaaggaa
     3721 acctggcttt gaccgggacg gaactagatg aattgacaga agatcaacta aacgaagttt
     3781 tagaaaaagt cactgtttat gcacgtgttt cacctgagaa taaaattcgt atcgttcgtg
     3841 cttggcaaaa taaaggtcat atctcagcta tgacaggtga tggtgtaaat gacgcaccag
     3901 cattgaaaca agcagacatc ggaattgcta tgggaacggg tacagatgtg gcaaaagatg
     3961 cagcagcgat ggtattgacg gatgataact ttgcttctat tgtcagcgca gtagaagtag
     4021 gacgtaatgt gtttgataat atcaagaaag ctatttctta tctatttgca ggaaatttag
     4081 gtgcgatcat tgcgatcatc tttgccttag ttgctgactg gtccaatcca tttacagcat
     4141 tacaactgtt gttcatcaat ttagtcaatg attcactgcc agcaattgca ttaggtacag
     4201 aaaaagctga acctgctacg atgaaccgcc cgccaagaga tccaaattca ggaatcttta
     4261 cggacaaaac attgatttct gtaacgtatc gtggtgtgct gattgggatt gctgttatct
     4321 ttgctcaatg gcttggcatg cagcattcac ctgaattcgg tgtagccatg tcattttcaa
     4381 cattgatttg gtgtcggaca ttgcaaacat tcccagcacg ttcaaacaca caaacagcta
     4441 tccaagcagg gttcttctct aacagaagtg tcttactagc tgtagttgta tgtagcgcgc
     4501 tttactgctt aacaatgatc ccaggactga aagaagtctt ctctatccca tcagcatttg
     4561 gattgacaga agtctttaca tgtatgggaa tcgcacttgt gacaattgtt ttgatggaaa
     4621 tcactaaatt gatcattgta cgagtacaag gaaataaata aaacgaatca acgaggttgt
     4681 gagcctgccg tttaattctg agtcacaagg tgcaatttca acaaacagct tctcatgttt
     4741 gttgaatatt gtgacttgtg accgaagagt tggcaggaga acaccgttta aggaagaagt
     4801 tgtaaaatca gcattttgag ctaatactga gggtcatctg attggacact gtttattcgg
     4861 aaagagggac tttgacacga ctttggtcac agtccctttt tttatttatg atagacggaa
     4921 agccaatcat tttattattc atcaaaagag atagaataga taaaagagga gaatgattta
     4981 ttccgaaaag tgaaaacata taacaaaaaa ttagaggaaa tcaaatgaat gaaaaagaat
     5041 gggatgaatt tgctgaagaa tattatgaaa tccagcaaga atcgcaagta actattgctg
     5101 aagatgtaaa aaattatctg aaaacggaga aagtcctgcc tgctgaaaca gcagcagacg
     5161 ttgctggagg atctggcaga tttctttcct tagcaaaaga aattaatcgc tatgatttga
     5221 tcgatttttc ttcaggaatg ctagaaaatg caaaaaaaga agcagaaaaa aatgagttgc
     5281 caaatgtttc ctttatcaaa cagtcgttag aagaatttat ccaatcaaat gagacatatg
     5341 aaatggtttt tacagcagca aatccagcat tggtacatct tattcaatta gaaaaattga
     5401 tgaaaaagtc aagcaaatgg tgcgtgataa tcagagtagt ggaatcaatc gatgatgttt
     5461 tttatcctat cgaaaagcaa ctaggaatga tagaagaaga tcctaataca tcgccagttg
     5521 taatggatca atttgaaaca tacttaattg atgaaggatt caaagtgaag aaaaaagatt
     5581 ttacttattt tacacaggaa tcaattactg aagaattgat gaagctatac tatgacgcgt
     5641 acgcaaaaga tcctgttgtg accaggtaca ttcgcaaact attcagtgaa aaacgagaaa
     5701 tccttagtac gactaagctg acctatagac tgctcctttg gtccgcagat aaaaaaagaa
     5761 cctttcacga ctcgtgaagg gttcttttta tgattttatt atattttgta gtaacgaata
     5821 tcattttcga tctttgtaat cgaaaaaggt acatctgaag tatattctgc acattctccg
     5881 tgttcaggaa gcgtctcact gaaaatcgtt tcatattcgt caacagtgat ccgtgttcga
     5941 gaatctagca tctcttgatg agattgtgcg aagagatatt cttgatagtt ttcttccaga
     6001 taacctgtaa aaaattcact tactgcacca gaaccgtagc tgaatagacc gatgcgatct
     6061 cctggctgta gtgatttcga attttccagt agagaagtta gccccaggta taatgaacca
     6121 gtgtaaagat taccgattcg tcggctgtaa cggatgcttt cttcatagcg agccataaga
     6181 cgttcctgat tttcttcgtc tgtttggtct aatacgcttt gcaatgcctt ttttcccatc
     6241 ttagtatacg gaatatggaa agcaatcgcc tgataatctt cgagtcctcg acccgacaat
     6301 tctttatgtc gattccaaac tttttggaat gattcgatat acgtagaatt agataaagga
     6361 ccatcaacaa caggaaattc gctataatct ggacgccaga aatcatagat atcttctgtc
     6421 agaaatacgc tgtcgtcttc aatcgataaa atacgcgggt tttgagtgat catcatcgca
     6481 acagcaccga caccttgcgt cacttcacca ccgcttgcca agccgtaacg agcaatatca
     6541 cttgctatga ctagtacttt tcgttctgga tgatttttga catattcttt cgccatgtgc
     6601 aaagctgcgg tgccaccgta gcaagcctct tttacttcaa aagaacgagc aaaagattgg
     6661 attttcagta aatggtggat aattaccgca ctcgcttttg aatgatcaat cccggattct
     6721 gttccgacga tgaccatgtc gattagctca cggtcttttt ctgttacgat tttgctggca
     6781 gcatttgctc ctagtgtaat gatgtcttca tttgcacgat tgactgccat ttggtcttga
     6841 ccaatcccta tatggtattt tgcaggatca tccccacggc tttctgccaa ctctgtcata
     6901 tctaaatata aattaggaat aaaaaaggaa agacgatcaa tccctatttt catttcaaca
     6961 cctctttact tatgataaaa aacttacttt actaaggtat cataaaaaga ttaaaagaaa
     7021 tataaaaaag agaatattta aggattgtta aaatttaatc ttagaaaaaa ataactggaa
     7081 caagagctat ttgtttttac agcaaagaat ggtatatttt tgtaggaggt ggcttacttg
     7141 aaagaagtcg ttatgataga tgctgcaaga acgccgatag gaaagtatcg cggaagttta
     7201 agtccattta ctgcagttga attaggcaca cttgtgacta aaggattatt agataaaaca
     7261 aaactgaaaa aagataaaat cgatcaagta atatttggaa atgtcctgca agctggtaat
     7321 ggtcaaaatg ttgccagaca gattgctttg aacagcggtc tccctgtaga tgtcccagca
     7381 atgacgatca atgaagtttg cggatctggt atgaaagcag tgatcttagc acgccagctg
     7441 atccaattag gtgaagcaga acttgtgata gccggcggaa cagagagtat gtctcaagca
     7501 cctatgctga aacagtatca gtcagaaaca aatgaatatg gtgaaccaat ttccagtatg
     7561 gtcaacgacg gattgactga cgcattttca aatgcacata tgggattaac cgcagagaat
     7621 gttgcaacac aattttctgt gagcagagaa gagcaggatc gctatgcctt gtcgtcccag
     7681 ttgaaagcag cacatgctgt cgaagccggt gtattttctg aggagatcat cccagtcaag
     7741 atttctgatg aagacgtgtt atctgaggat gaagcagttc gtggaaatag tacattggaa
     7801 aaactgggca cgttacgtac agtattctca gaagaaggaa ctgtaacagc aggaaatgct
     7861 tccccgttga atgacggtgc ctctgtggtg atccttgcat ccaaagaata cgcagaaaat
     7921 aataatctgc cttatttagc aaccatcaaa gaagtagcgg aggtcggtat tgacccaagt
     7981 atcatgggaa tcgctccaat caaagccatt caaaaattga cagatagatc aggaatgaat
     8041 ttatcaacaa tcgatctttt tgagatcaat gaagcatttg cagcttcttc tatcgtagtt
     8101 agccaagaac tgcagttaga tgaagaaaag gtcaatatat atggaggagc aatcgcatta
     8161 ggccatccaa ttggtgcaag cggtgcacgt atcttgacta cattagctta cggattgctt
     8221 cgtgaacaga agagatacgg tattgcttca ttatgtattg gtggaggttt aggcttggca
     8281 gtcttgttag aagcgaatat ggagcaaaca cataaggatg tgcaaaaaaa aaagttttat
     8341 cagcttacgc catctgaacg gcgcagtcaa ttaatagaaa aaaatgtatt gacacaagaa
     8401 actgcgttga tttttcagga acaaacactt tctgaagagc tctccgatca catgatcgaa
     8461 aaccaagtga gtgaagtgga aatcccaatg gggatcgcgc agaattttca aatcaatggc
     8521 aagaaaaaat ggattccgat ggcaacagag gaaccatctg tcattgcagc tgcaagtaat
     8581 ggtgcaaaaa tctgtggaaa tatctgcgca gaaacacctc agcggctgat gcgagggcaa
     8641 atcgttctat caggaaaatc ggagtatcaa gcagtgatca atgcagttaa tcatcgaaaa
     8701 gaagagctga ttctttgtgc aaatgaaagt tatccttcaa tcgtgaaacg cgggggcggt
     8761 gttcaagata tctctactcg ggaattcatg gggagtttcc atgcatactt atctattgat
     8821 tttttagtgg atgtaaaaga tgcaatgggc gctaacatga tcaactcgat tcttgagagt
     8881 gtggcaaaca agttacggga gtggttccct gaagaagaga ttctattcag tattttaagt
     8941 aattttgcta cagaatcatt ggcttctgcc tgttgtgaaa tcccattcga acgcttaggg
     9001 agaaacaaag aaatcggtga acaaattgcc aaaaaaatcc aacaggcagg ggaatatgcg
     9061 aagcttgacc cttaccgtgc agcaacgcac aacaaaggga tcatgaatgg tatagaagct
     9121 gtagtggcag ctacaggaaa tgatacacgt gcggttagcg cttcgatcca cgcctacgcg
     9181 gcaagaaatg gattatacca aggattaaca gactggcaga tcaaagggga taaactagtt
     9241 ggaaaactaa cggtgccttt ggctgttgcc acagtaggcg gagcttccaa tatcctgcca
     9301 aaagcaaaag catctttagc tatgttagat attgattcag ccaaggaact agcacaagta
     9361 attgctgcag tagggttagc tcaaaacctg gctgctttgc gtgcattagt tacagaagga
     9421 atccaaaaag gccacatggg acttcaagct cgttcattag cgatctcaat tggggctatt
     9481 ggtgaggaaa tcgagcaagt tgcgaaaaaa ttacgtgaag cagaaaagat gaaccagcag
     9541 acagctatac aaatattgga aaaaatccgg gaaaaataaa aaagcaatat ctttagaaga
     9601 ataaagcaag atttacagtt attttattta ctgcagatct tgcttttttc tctatcagaa
     9661 aatatgttta ttattagaat tttttatagt taaggttagg catcttaaga aatcaggcaa
     9721 ctccaagata tcttcaggta gaagagaagt cgcctaacat tgtaggatca taggtgattt
     9781 gttggacagg tcaagctgat atttgagcct gatgttagaa ggaatttctt tttacttgct
     9841 gtagaaatta ttatatgact aaaaaggctg ggattttaaa tcccagcctt ttatgacaaa
     9901 tagaattttt atcgatcagt aatcgctgtc gctgcaaatt gttcgatcaa aggaatcaaa
     9961 gtcaatttga ctttgtattt ccgttcgagt gctttttcga taacgaactc attttcagta
    10021 gtcatagaaa tagttgctaa tttacgaggt tcatcagcat ttttttcatt aataactact
    10081 tcatgttcat tttgttctgt gtaaaattta ggatactcag caacggcttt tgaaaaatca
    10141 gcaaaactta aagcggcatt cgtatcagtt gagcgtgtat tttcagttgt gtccgctttt
    10201 ggtttttccg ttttttcttc tggcacactg actgtttctt ctgtaactgg tgtcgcaaca
    10261 gcttgcgcag ttggttcatc gtttttcaat cgttgatcat tccagtaaga cacgatttca
    10321 ataagaagat tgtcacggaa tcgttcgaaa atcccgtttt ctcctgaacg aattctcttt
    10381 aatacagtat tgaagttgtc atcgattggc acgttgatcc gtgtatcttc atttgttttc
    10441 ccagctaatc cgatcgttaa gatttgacgg tttttgggat caagcatgac ttgtaacggc
    10501 aaaccataac gtcgcaagct ctcttcttct agagaacgga ataattgtcc tcttacacca
    10561 tccaatgaag gacggaattg atttaataat ttttgtttct gttttttctt catatgttct
    10621 ctccttcgct catacccttt cgattataag aaaaaaacag ccaaatgaaa aggagtaatg
    10681 caaaaaaact tgcgtatacg caaattacaa cagaaaaatt tgcgtatttt cccgtttttt
    10741 gaaagaaaaa taaaaaatgg aacggattat gtatatatac ataatccgtt ccattctttc
    10801 tattttttcg gtatcaaggc aaaaacaggt agttcaggtg aataaatgac ttcatgttcg
    10861 tgccagggtt tgaccattag cgaatgatcg aaccgttttt tcagttcttc gatgatttga
    10921 tcatgtgtcc agtttcttgc aggaaaatgt tggattttct ctgcatcgat caaaaagaca
    10981 aaatcggaat gaaaagtctg ggtaacttct tccgagagag aattcaagcg ttcgattgga
    11041 tccataaaat cacctttcga cttaaaattg ggtagtatct gggtcttttg ctttgccgac
    11101 tacaccatct aactgatcga tttgtttcat ttcttcttct gttaattcaa aatcaaataa
    11161 ttcagtattt tctttgattc tgcttggtgt cactgactta ggaagaggaa ggaattcgtg
    11221 ttgcagcgac caacgcaaag caacttgtgc aatcgtcttg tcatgtgctt cagcgatttg
    11281 tttcatttca ggcacatcga agattttacc agtgcctaat ggactatatg cttcgaggat
    11341 catatcatgt ttttttgcat actcaactac agttgtctgt aattcgcctg gtgcaaggaa
    11401 aacttgattg accatcggca taatttttgc tgtttttgct agtgtatcta gatggtgggg
    11461 taagaaattg ctcacaccga ttgctttgat tttacctgct tcatacagtt cttcaaatgc
    11521 tcgccatgta tctgcatttg cttgttccca attatcacga aaagcaacag ggtttggcca
    11581 gtggatcaaa aacagatcta aataatctgt ttggagcttc ttcaatgatt cttcaaaaga
    11641 agacatcaca agttcatagc tgtggtttgc attccataat tttgttgtca agaatatctc
    11701 ttctctagga attccacttt ccttaatcgc ttggccgacg ctttcttcat tcttgtatcc
    11761 ttgggcagta tcgatatggc gataacctgc agccagcgct tctttaacag aggaaacagc
    11821 gacatcccca tcaggtgttt gccatgtgcc gaatcctact accgggattt cgtaaccatt
    11881 tgatagacga taagtgcttg ttaatgaatt catactttca gctccttttt tattcgttca
    11941 actataagtg tagcgcattt ttcgaaaaaa agaatccatt ttgtttctac tcttgaaatt
    12001 tttgtttaaa agaaaatgat tttgattctg gtatttttga ttttttttcc gtaaactaag
    12061 acagaaggga atgagaaaat ggatatctat ttaaaaaaag caattctgca tattattgac
    12121 agagaaactg gttctccagt cttttcacaa aaagagctgg atctgacaaa agaatatatt
    12181 cgtgattttc ttcaaaagaa gatccaaaaa atctcttctg ctcaaacaaa aactggacaa
    12241 ctagcagaag aaagcatgat cgttgaatca cttaaaatcg ctcaagaaaa ttttgtggaa
    12301 gcaagtgaag caatcgttca gcggtggttc gatatctacc aagaaagtga agaagcacct
    12361 agtgcagatg tatttgttgt cttgtatgaa ttagatacag tgatgtactt atctttattg
    12421 aaagtcaatt atcgtgaggc ttacactcac tttgttgaag cagacgaagc agggatcgac
    12481 aaccgcttga ttttgaatcg agcaattcta ggggcgaaaa cacaaaaagc agatgaagca
    12541 ttcgctgtga atttgactga ttggacctac gaattaattg aaaaaaaata tgagttttct
    12601 ggcaaaaaag agctttattt ttctggaaga gtgatcgaaa gtgttcctgc accttcttta
    12661 gaagaaaatg taaaagtgat ccaaaaagta gccaagcatc ttggaaaaaa atttgagaca
    12721 gaagaatttg atatcatggc tgatttgaaa gaagctgtct atgatacgat agaagaaaaa
    12781 ggtcggttgg atcatgagat gattgcggaa aaagtcttca aggaaaacat cacggcaaaa
    12841 atggctttta aagaagaagt acaagagcaa ggatttgtcc cagaagcacc tcctgtaaaa
    12901 gaagtacaag aaatttctga gaaaaaattt ggaaaacaaa aattcaagct atcaaacggg
    12961 atcgaactga tcgtaccagt agatgtatat cgcaacccag atttgattga atttgtgaat
    13021 aatccggatg gtacgatatc cgtgatgatc aaaaatgtgg atgaagtatt gaatcgttta
    13081 taaaaatgac tagaatatta ggtgttcaag taccagtgat cagttaaatg aattgtgtca
    13141 agagaaggat cggaaaagac gaatataaca aaaaaagagc gtgagacaaa agtaaagaac
    13201 acttttgtct cacgctctaa acacgtataa acggcggaag cagaagcaac tccttcttat
    13261 ttcttggagt taaacgcttc tgtcccagcc tctttttatc taataaaatt ttaagaccat
    13321 ttactaatta tcgatttttt ctgccgcatt tttaggcact tcagaagcct ttatttcttc
    13381 ccagcttaat acacctttac gaggattgac tttgagttta agatacgcat tcatctttaa
    13441 tggatgttct ctttcttcgc gaagcgtcac ctgttttttt tcaccatctt tattataagc
    13501 cgcttgcttg taggtataag tcgtgaattt ctctccgtta tctgcttggg tagctgacat
    13561 ttcgccattc gtcgtgattt ttgtataata agcttcgccg ccgtaaaaat aatgataagc
    13621 tgcaaaactt ccgccgagaa atatgcctaa aacgacaagt acgccaatta attttttcat
    13681 gtacttcacc tctttcctta ttattaacga aatagaagat ttcgtctatt gaaagttgtt
    13741 ggcaacagct gaattttaaa cttttcctca ttttgttctt attgcttcaa aagaaagtta
    13801 aggactatct tgaagttttt ctcaaaaaac acattttttt atttataaaa ggtacttttt
    13861 tcgcgtataa gacagacgag tgctcttagt tgactttgac caatattgac gtataataag
    13921 cttagttcga atcttacaaa aagtaagtcg gacctattct ttttgattta gtcaaaaaaa
    13981 gactataata aaaaggtgag agctgaaatt tttcagtgat ctatattatt taggaggttt
    14041 gtaaattatg gcaaaagaac attatgacag aagtaaacca cacgttaaca ttggtacgat
    14101 tggacacgtt gaccatggga aaactacttt aactgctgcg atcactacag tattaggcaa
    14161 aaaaggccta gcaaatcctc aagactatgc tagtattgat gcagctccag aagaacgtga
    14221 acgtgggatt acgatcaata ccgcacacgt agaatatgaa acagaaaaac gccactacgc
    14281 gcatattgat gcaccaggac acgcggacta tgtgaaaaac atgattacag gggcagcaca
    14341 aatggatggt gcaatcttag ttgtttctgc aactgacggt ccgatgcctc aaacacgtga
    14401 acacatttta ttgtcacgcc aagttggtgt aaaatacctg attgttttct tgaacaaagt
    14461 tgatttagtc gatgatgaag aattgatcga tttggtagaa atggaagttc gcgagttatt
    14521 gagcgaatat ggtttcccag gcgatgacac tcctgtgatc aaaggttccg cattaaaagc
    14581 attgcaaggc gatccagatg ctgaagctgc tattatggaa ttgatggata cagtagatga
    14641 atatatccca acaccagaac gtgatacaga taaaccatta ctattgccag tggaagacgt
    14701 cttctcaatt acaggtcgag gaactgttgc ctcaggtcgt attgatcgtg gtgctgttcg
    14761 tgtcggtgat gaggtagaga tcgtagggat caaacctgaa acacaaaaag cagttgtaac
    14821 aggtgtagaa atgttccgta aaacgttaga ttacggggaa gctggggata acgtaggcgt
    14881 gttgttacgg gggatccaac gtgacgatat cgaacgtgga caagtacttg ctaaaccagg
    14941 ttccattact ccacatacaa aattcaaagc agaagtgtac gtgttgacaa aagaagaagg
    15001 tggacgtcat actccattct tcaacaacta tcgtccacag ttctacttcc gcacaactga
    15061 tgttacagga acaatcacat tgccagaaga tacagaaatg gtcatgcctg gtgacaacgt
    15121 gacgattgat gttgacttga tccatccaat cgctgttgaa aacggaacga cattctcaat
    15181 tcgtgaaggc ggacggacag taggttcagg tatcgttaca gagatcgaag cataagaaac
    15241 gcgactcgaa tattttggta atgaaaaatg tttaaaataa aagagcggtc caaacaggat
    15301 ttctgtttgg accgctcttt gttcttcaat tgtataagaa gagattgtag aagcatgaac
    15361 tttcgtttta cttcagtctc ttttattcat catgagagtg ttcatctatc ggtatgcagt
    15421 ttttaatact ttcttcgtat ccattttttc aaaccactta ttctaccttg tgtctgctca
    15481 actggcgcat tatcaataat cagcaaagca atcataacat atgcaatcca actatctcta
    15541 gaatatagag tataacgtga gacccagttt gtagcgtact tgcttttata ttctcttaat
    15601 ccatggaaag aataaaaatg agaaccaaac tcgtaaacca agtatgcaat cctttcctgt
    15661 aaaaaactct ttctggaagt tccgacattt gaaagagggg ccatccctaa attgaaccat
    15721 tggatatgtt cttctttcat ataggcaaac aaatgcaaga acaagaaatc catactgcca
    15781 gaaggtgctt ttttagaatc atatcgcatc agatcaatcg ttcctacttt attgttcgtg
    15841 taagtaggca tgatcgttgc aaaagcgaca atttcttctt gggtattttt gacaactgca
    15901 ataggcgctc tttgtagata atcttcagag aaaaagccta aagaaaaccc tttttccttt
    15961 cgtgaaccca accaattatc agagatattt ttgaaagtac tcatttgctc agtagaaaat
    16021 ggtggttgta agacatcaaa tgtaaatcct tctcgttcga tccgattcaa gacagcacga
    16081 gtgcccttca tttttttccc tgaagttgta aaactattca ggtctacata agcttcttcc
    16141 cccatcttaa tgaaatcgta gccgaattca tgcaaaatca taacaatctc ttcgcttgtt
    16201 tcgtagaaaa ctggtaaata gcatagtcga tctgtttctt cgataaaagc ttcgattgct
    16261 tctggaaaat cttctttctt accagaagga tcacccatta caatacattt attattgaag
    16321 caagcgaatt ggagaagaac agttggttca ccgtcttttt cataggcaaa catccgctta
    16381 tcttttaaga agatcaattg actatcggag tttcctccat aagttgtaag gatcttcagg
    16441 gccttttctt cattaaaggc ttcgccaatc tgtttctttt ctccttgaag gaaatgaaca
    16501 aatagaacga tcatgaaact aacagcgatg atggccaaca atcccgaaaa ccaaatcttt
    16561 tcagaaggaa ataagaaaaa ggaaataaaa tggtgacgcc gatgagggaa atccggcaga
    16621 ttgtataccc caataacgat gtaaagcaag gacagtgcac caataatgat tccatcgatc
    16681 gtacgccact cccatgaata gatcaattgt tcccgaaata attcgttttt agaagcaaga
    16741 atgatcagaa gcagaataga caagaaaacc accggtgtga aactaaaatc acttaataaa
    16801 acataaagta aagctagaac aatcaagaag attgtaggca aatatgctcg tttcacacgt
    16861 gctgcgatcc ctctgcccat aatgattaaa agaaatccca atagtatact aggaaattgg
    16921 ataataaaat gaaatttcaa tgggttcaaa ctatgaagcc agcgaaactc tgtaaaagct
    16981 tgcgggatag tggcagaaag tactagcatg attccagaaa agtataataa gacaaccacg
    17041 attttatgcg caatttctgt tgctaattgt ttagggatac cagaataacg ctgatcaaaa
    17101 gtggaaccga tatttttgaa gaaaaagacg attccaatca aaaacggaat gatgtagtag
    17161 aacaggcgat agagcaagat ccacacaacg actatttctc ttggcacacc aatagcggac
    17221 aacccgataa tcatcattac atcgaaactc ccaatttctc ctggaatcat agacacgatt
    17281 cctatcactg aagcagcaat gaataatgga attgtttgcc acagatcaat ccggatttcc
    17341 attaaataac caacagaaag gaaactaaac aggacaccgg tccattccaa caatgaaact
    17401 agcaatagct gtccttgagt tttaagtgag gtaccaccaa ggaatccttt ctttttgaaa
    17461 gtagtaaata aaaagacgac aggaaaatat agaccgccgc cgatcaacca tatccaatat
    17521 tgcttcaaaa aaggagcaac tggcgtgaag actacaagta aaaaagaaag cagactgtaa
    17581 atagaaagtc cagccatcaa aaacaagaaa actttcgata atgcttggat cacgtttctg
    17641 ctctctttct tttgtccata tagttcagag cgaagcccca cactaacaaa cccgccgaaa
    17701 ccggcaatat tgttgatcgt attgatcagc cagcttgtct caaacaggta acgaggattc
    17761 tgcttttgtt caagcatccg attcaaaata atatcataac caaccatagg taacacagag
    17821 ataagaccaa tcaatagcat tagtccgctt ttccatacag gtatagtggc aaacgtttct
    17881 cctaattgct ggatagatag agttttaccg atggacatca attcaccgac aataatgaca
    17941 atgacagaaa tcaaaaagat tgttttgaac agtcctaggt ggtttttcag ccattgtatg
    18001 gtatttttta acaaataaat caccttctat tcctaatagt tatgtttcag aaagaaattg
    18061 aagaacttct cgattgaagc gttcaggatc ttttctagct aattcatgtc cttgttcttt
    18121 cacaagcaca aaggaagctt ttggtatagt tttagctata tacaaagaat gttttagctt
    18181 gattacatct ttttttccca cgatgatcaa agtgggggag ttgatttttt ttaaatcatt
    18241 ttctgtaagc ccgatgtcat gcagcaaaag tttgataact aaaagatttt tgcgaagact
    18301 tgggcgaaat aaagagagta accataccca tgcataatga atattactga tgactctggc
    18361 agaaaaacga acgcctttaa caagcgtgtt tccagaattt aaaatcaatc gatgaacttt
    18421 tttagggaag ctgctggcaa ataccagtgc tagatttgct ccatcactaa atccaagaaa
    18481 atctgcctga tcgatttttt ccagcaacat gatcgtattc agatcctcgg ccattaactg
    18541 aaaattcaac atagatgctt cgtttgtcga acgaccatgt cctcggctat ctactagata
    18601 cacggtatag tagcgttcga gtacagggac ctgttctgaa aaaaagcggc cgctgccgtc
    18661 attgccatgc agtaaaaaga gagggaagcc ttgaccgctc ttttcatagt aaatttcgct
    18721 cccatctggc atttttgcat atttcttttc ttttttcaca taatcaccta ctgtgtaaag
    18781 tataacgatt atatcagtca ttgggcaatt gtttttactg aaaaacaacg atcattttcg
    18841 taagatgtca aaaaatacag gaaaattcat tttttcttaa ggcgtacaca gaaatcaagg
    18901 aagaaatagc caagaagata aagaaatagt aagataaaaa aagatgtcaa aataactagg
    18961 tgatgaaatg aagcgaaaac gattatctat tatccgtatt cttttttaca tgatcattct
    19021 gacggttatt ggtgcggtgt tgtttttatg aggaagaact tatcgttcgg taaaacgagt
    19081 ggaaagctat caaatagaaa taacaacagc tgcaaaaaat tatcatatgg aaaactacga
    19141 gaatttgatc aaggcgataa tattgaccga atcaaaagga aaagggacag atctcatgca
    19201 gagctcggaa agtctgcatg gagaagctga gatcattgat aatccagctg acagtattga
    19261 tcaaggtgtc aaatatttgg cggaaatgat agtagaagca aagaaacaag gatgcgattt
    19321 atggacagct gtccaagcat ataattttgg gaaagattat attgcctatg taaaaaatca
    19381 tggcggagaa aacacagtag aattagcaga agcgtattct aaagatgtgc tgagcccact
    19441 tttaggaaat gaggaaggga aacaataccg atattggcgg atccagtcct tgctttacaa
    19501 tggcggctat ctctatcata atggaggtaa catgttttat cctgatattg tcaaaatgaa
    19561 tgaaaaaata atagagacct atgaaaaagt ctttaagtaa aatagcagga aatgttcaat
    19621 catgaataaa attaaatgaa agaaggagtg cgcaaatagt ggaaaaaagg caaaaaatgg
    19681 aaaatcaaga agtggggtac acaaccaaag actggatgtt acggtttgtg aagggaatgt
    19741 ttatcggttc aggatttatc ttgccaggag tcagcggtgg tgcattagca gctgtctttg
    19801 gcatgtatga gcggctgatt tcttttttag cccaccttac aaaaaatttc aaagaaaatg
    19861 ttttgttttt tctgcctgtt ggtctaggcg gagtgacagg catctttcta ctttcttttt
    19921 tagtcagttt tttattaggt gcgtatgaaa caacgatatt atggtttttt gtcggatgta
    19981 tcgctggaac tgttcctgcg ttatggaaag aagcagggaa aaaaggaaga gatacttctg
    20041 atgtgatcat catggttgtt acttttgttc tggcttattt gtttttatta tacggcgctc
    20101 aattatttga cgggcaagtc gatcagaatt ttggaacatg gctgattgcc ggcggattga
    20161 ttggtttggg tatgatcgtc ccaggattga gcccttctaa ttttttggtg tatatgggat
    20221 tgtataaagc gatggctgac ggatttaaag aagtacgact tgaagtgatt gtgccgatcg
    20281 gaattggtgg gattctttgt gttcttggat tgtcaaaaat catggattac attttctcaa
    20341 aggcatatag caagctattc catttcattt taggtgtagt ttttgcttca acgattatga
    20401 tcattcctac cgattacgcg ggattgggag ttgctggggt actagcttgt cctgttcttt
    20461 ttatagccgg tacagcacta ggttggtgga tgagccgttt ggaggaacaa tataagtaaa
    20521 gatagattga taataaaaac agcacacggg tgattcaaac aaaaaggttg gcatcttttt
    20581 tgtaaaatca ttcgtgtgtt tttctataaa ttttataaaa acaagttgtt tttaatcttg
    20641 gaacacgcta gacttaaaca cgtgattatt tttgaaagtt ggcggaaaat ggagaaaaag
    20701 aaaatgaatg gacttacaca gcaagaggta gttcagaaaa tggcttctgg ccagcaaaat
    20761 gactaccagg aagatgcatc aaaaagtaca aaacaaatat tcagcgataa tatattgacg
    20821 ttattcaatt ttctgaactt tggtattggg atttgtctgt tatttgtagg tgcgtattcc
    20881 aacatggcgt atttagcaat tattgtcgtc aatatcgtta ttggaattta tcaagaaata
    20941 catgcaagaa atcttgtacg gaaattatcg attgtttccc aatcagaagt actagtgatc
    21001 cgggacggta aagaacaatc gatttctact aaagagctgg tattaggaga tttggtaaaa
    21061 atcggagcag gagaacagat accagccgat ttacaggtta tatctggacg ggcagaagca
    21121 aatgaagctc ttttgacagg cgaatctgat ttgattgtca aagaaactgg agctgaattg
    21181 ctttctggaa gctttttgac aagcggttct gtcatggctg aagttatccg agtaggtgca
    21241 gataattatg ctgtccgctt gactagcgag gcaaagactc acaaagctat tcgttctgaa
    21301 cttgtagatt cgattcgcaa agtatccaaa ttcactagtt tcgtgattat tcctttgggg
    21361 atcatactat ttttggaagc actgttcatc cgcgatgctt ctatcaaaat ttctgttatt
    21421 gcatctgcag cagctttgtt aggcatgctt ccaaagggtt tggtattgct aataagtatt
    21481 gcattaacga caggggtaac caaactggca aaaaaacgaa tccttgttca agacatgtat
    21541 tcaattgaaa cgctggccca tgtcgataca ttatgcttgg ataaaacagg gaccattact
    21601 gaagggaaaa tgagtatcca gcgggtagaa gcactacatc cgctgtacga gaaagccatc
    21661 ccagaaatta tggggacgta tctggcagaa agcagtgata acaacatcac tatgcgggct
    21721 atgagagatt attttgagct ttctaatcgg tatgatgtga caaacaaagt cgcattttct
    21781 tctgatcgca aatggggcgc gatggaattt ccagaactgg gagtcgtgta cgtaggagcg
    21841 cctgaacgtt tggtggaaga agatcggctt ccggacagtc taaaaacagc ccaagcgaat
    21901 ggctatcgcg tacttatgtt ggggatcgct ccaaatcagc aattgaacga agaaaaacca
    21961 gcatttgttg agccggttgc tctgtttgaa atcgatgatc caatccgaaa aaacgctcaa
    22021 gaaacactag cttatcttca tgaggaaggt gtggatctga aagtgatttc tggagacaat
    22081 ccttttactg tctccaatat cgctagacgt gcaggattac cgaattatga tgcgtatgtc
    22141 gatctttctc aaattactga agaaatggaa gtgcgagaag ctgctcatcg ctatacggtt
    22201 tttggacgag tgagtccgca gcaaaagaaa ttgctggtaa atgaattgaa agaaagcggc
    22261 agaacggttg caatgacagg cgacggtgtg aatgatgttt tggcgttaag agaagcagat
    22321 tgcagcattg ctatggcaga aggtgatgga gcaacacgtc agattgcgaa tctggtattg
    22381 ttggactctg attttactac attgccagaa gtcctgtttg aaggacgccg agtggtcaac
    22441 aatgtgacga aagtctcagg catctttttt atcaaaacga tttattcatt tattttatcg
    22501 attatatgtg ccgttacagc aattggattt ccgtttatcc ctatccaaat cacgctgatt
    22561 gatttagcga ttgaagggta tccttccttc tttttatctt ttgaacaaga taaaagaaaa
    22621 atcacttacc gttatttgcc tacagcactt attaatgctt taccaaatgc cttgcttgta
    22681 gtagtgaata tcattgcggt gtatctactt ggaaaaacat tcgcatgggg aaatgctgaa
    22741 actactactt tgatgtatta cttgctgatt gggatcagtt gcatggcagt tgtaaaagct
    22801 tgttatccct tcaacccatt gcgcatcttc ctagcagtaa cgacgatcgt agggatatat
    22861 gtagctgcaa tgctgttcca tggaattttg gaagtaaact tagggttggg agagagcgta
    22921 ggatacttct ttgtattcat gctcgtaaat attgttcttc gagtattgta ctggaaggct
    22981 gatattcaaa atcagttact gaaaagagta gcaaattgat gcttaatgag atagaaatgt
    23041 gttatacttg aaaaagcaat gaaatatgat acaatcaaac atgtataatt gtgtccttta
    23101 aaatcgcact gatttcagtt agtgcgattt tttaccggtt attctcctga aatatcttct
    23161 gttaaaccca aaagatatca atagagcagg gggtgaaaaa atggctcaac ggattcctca
    23221 agaggttatc gaaacagtac gcagtcaaac gaatatcgtt gaggtgattg gacaatatgt
    23281 ccagttgaaa aagtctggta aaaattactt ggggctgtgt ccttttcatg aagaacgtac
    23341 accgtctttt tctgttgcag aagacaagca gatttttcat tgctttggtt gtggtaaagg
    23401 cggaaacgtg tttacttttc ttcaagaact agaaggtcta agttttccag aagcagtggt
    23461 aaaagtggca gacttcgaac agataccgtt agaagatcaa tggcgtcagc gtactatagc
    23521 tgtccaaaat cctgaatctg ctacggggaa actgattgct gctcatgaaa aagcagcgga
    23581 aatctatcat cacatgctat tgcatacaaa agctggacag ccagctttag aatatttgca
    23641 aagtcgtggg ttgtctttag aattaattga agaattcaac ataggttttg cacctaatga
    23701 gcgttctttt cttcagcaag tattcaagaa tgaatcaatt tcaaatgaat tgttagaacg
    23761 ctctggattg tttgtcacgc atgatgatgg ccgtatgtct gatcgttttt atcaaagagt
    23821 gatgtttcca cttcgtaatt ctcaaggcca gacgatcggt ttttcaggac gctggcttgc
    23881 acctgaaaaa gggcaggaaa aagatcagcc caaatacttg aatagtccag aaacagaact
    23941 gttcaataaa agacaagttt tatttaatct tgataaagca agaagcgata tccggaaaaa
    24001 cggagaaatt ttgttgttcg aagggtttat ggatgtgatt gctgcatggc aggctggtat
    24061 caaaactgga ttagcttcta tggggacaag tctaacagct caacagatcc aacaaatgga
    24121 aaagctgacg aaagaattgg tcttttgcta tgacggagac aacgcaggtt ttgaagcaac
    24181 caatcgaggg attgaattgc ttcggcaaaa cagtcgatta gcactttctg tcgtagtcgt
    24241 tccagaaaag cttgatcctg atgaatatct ccgtaagtat ggagaagcat ctttccaaga
    24301 attagtggct catgggcgcg aaacagtctt tacttttaaa tcacgttatt taaaacaagg
    24361 gaaaaattta gataatgaaa aagacaagat cgaatacctc gaagaattac tagttgaact
    24421 tagccgagtt gtttcaccaa tcgaacaaga tatgtatcta tctcaactgt caacagagtt
    24481 tcagatcggc agagagacga tacaaaaaca actgcgcgat cttcgaagga caaatcagca
    24541 aaatcgtcaa gaacctcagg aaagtcaaca cactcaggtt acgagacaag aaactgcacg
    24601 gaaaaagaga cctttgacgc aagtagaaaa ggcagagcag attctattat atcgtgcatt
    24661 taaagaagtt tctgtccgta atattttaaa agaacgagaa tttcagttta ttcatgatgc
    24721 atatgcagaa gtttattttt tattcgatgc atatgtctca caacattatg aattcaacct
    24781 tgcagagttt ttagactttt tgcaagatga aaatttaagg cggttggtgg tggaaatcga
    24841 atatttaccg gtggcagaag aaagttcgcc acgagaaatc caagacttgc tagatgtgat
    24901 cagcaaatct ggcttagctg atgaaataac attaaaaaaa caaatgcagc aagaagccag
    24961 acgaactgga aacaaacagc ttgagcttga attgacgatt gaaatcatca atttaacgaa
    25021 acagttaaaa caagccaaat agctactcaa ggggggcctt cttttatggc aaatggaaca
    25081 gataaaaaaa cgtatgaagc agcagtagca gctttcatca aagaaaacaa acccaaacga
    25141 caagttgtat atgatgattt atccaatcag cttgctacac cattcacttt gaatgcagat
    25201 gaaatggaca aattgatcca aaagattgaa gacgcaggta tcagtgtggt ggatgaaaat
    25261 ggtgatccat caattcacag cttgaagagt gctgagaaaa aagctgaaca agcaaaaaca
    25321 gaagatcttt ctgcgccaac cggtgtaaaa atcaatgacc cggttcgtat gtatctgaaa
    25381 gaaattggcc gtgtctccct tttaactgcg gaagaagaag tagcgttagc attgaaaatc
    25441 gaagaaggcg accaagaagc gaaacagcgt ctggcagaag caaaccttcg tttagtagta
    25501 agtatcgcta aacgttatgt aggacgaggc atgcagttcc ttgacttgat ccaagaagga
    25561 aacatgggac tgatgaaggc agttgaaaaa tttgactacc gcaaaggatt taagttttca
    25621 acctatgcta catggtggat tcgtcaagcc atcactcgag caatcgctga ccaagcacgt
    25681 acgatccgta ttccagttca tatggttgaa acaattaata aattgatacg tatccaacgt
    25741 caattgctgc aagaccttgg aagagaacct acgccagaag aaatcggtgc ggaaatggat
    25801 cttccaacag aaaaagtccg agaaatcttg aaaatcgcgc aagaacctgt ttcccttgaa
    25861 acgccaatcg gtgaagaaga tgactctcac ttaggtgatt tcatagaaga ccaggaagca
    25921 acaagtccag cagaacacgc agcttatgag ttactaaaag aacaattgga agatgtacta
    25981 gatacattga ctgatcggga agagaatgtc cttcgcttac gttttggttt agatgatggc
    26041 cggacgagaa cattggaaga agtagggaaa gtatttggtg ttactcggga acgtattcgt
    26101 cagatcgagg ctaaagcatt aagaaaattg cgccatcctt ctcgttcaaa acaattaaaa
    26161 gatttcttag aataagcgtg gactattgac cagaagagaa atcagtaaaa ctgtttggtt
    26221 tattttaaaa gaaaaaaagc ttgagactac gcagtctcaa gctttttttt ctataggaag
    26281 gaaattcatt cattattttt aagtaaatcc taaaaataag ctattggcgt gacgtataga
    26341 atatgataga ttaaatggta gcgtaaacct agtaaaggag ccgatcgcta agtgatgaaa
    26401 aaatgtccaa attgcggatc gaaaaaaatg gagcagaata ctatctgtcc agactgcggt
    26461 catcaaataa ctgcagaaga tcagcaaata aaagaatcaa ttgaagaaac aaatacagat
    26521 gcagctatgc aggataaatc aactgaagat gcagtctttc ctgatacaga attaaacgat
    26581 ccaatcgaat ggtcggaatt gaaagattta cctctagaat ctgtaatgga attattcgaa
    26641 aaagcagaac cagaagacga agaaccacct gctcacgatc aagtaactaa tatagagaaa
    26701 aatgaacaga agaaagcaac tgttcatgag acttcggaag aatcaggaaa gaatcaagaa
    26761 gaaacgcttg aatcaaaaca aaaaagaaga gtagctgaac tgaaagaaat cgtcgataat
    26821 gaggaagaaa attcgatact atccgcttat atcaaagcac atcgtgaaga tacaaaagaa
    26881 gagcacgcga aagagctgct caaaatgatc agtgaaaaaa ttgcacagga aaacaaagta
    26941 gagccagaaa aggaacaaga aactgaaaaa gactctgata gagaaaacgc cacaggtaaa
    27001 gaaacagtaa aaataaaaga cgtaaaaacg gatatcacag aaaaaactga agtatttact
    27061 gaaaaacaat tagaaaagga aaaaacgaat aaactgccgg aagcagagaa aaaagaaata
    27121 ctcgaaaaca cagacaaaaa gtcaacagag cccgatgaaa taaatagtga atccgatgct
    27181 gaaaatcaat ctgtaagcaa agagggtact gatcttgaag caaaaataga aaaagaagag
    27241 aaccagccta agctgtttga agcagaagcg aaatcaataa caatcgtgcc agatactgaa
    27301 aaaacacatc aagaatcaaa cttagaaaaa acagatccag ataaagcgca aaagaaaaaa
    27361 tcaaaaaaag taccttatct cgttttagca gcagtacttc tactcggtgg aggaagctgg
    27421 gcttattatg accatcatca aaaagtagaa gccgaagtag cagcagaagc aaaaagacag
    27481 caacaaatgg aagaacttca tgagaaactt gctgcctttt atacagatga tcaccatcaa
    27541 tttattcgtg cagatatgat tcatcaagat ttatcaaaac taaaaaatga tttatccagt
    27601 cttaagaatg aaaaaggata ttcagagtta gaaacaactt accaagatat ccaatctaag
    27661 atccgagata tccaaaaagt gaatgagtgg ttcatagcac ctgccatcgt cgatgatcat
    27721 ctagcagatg acatcaagtt gaaagcagat aaagagatcc aagcaatcga aacggataac
    27781 acagattttg gaaaattgat tcaacaagca caaacagaag ctaaaaatca atatgctgaa
    27841 ttgcaaacag ctaaagaaaa aacagctata gtctttaaag acggaaaagt agtggattca
    27901 gcaacacgcg accaatacaa gacggcaaaa gaagcagtag aaaaagtgaa aaatacagat
    27961 ctatctgctc agttgaatga acaattgaaa caagtagata agatgctcac tgataaagag
    28021 aaaaaagaag aagaggaaaa gaaaaaagca gaagaagcga aaaaagcagc tgaagaacaa
    28081 gcaaaacaag ccgctcaagc agcagctgca gctcaagccg ctcaacaagc tgcggtcgca
    28141 caagcagcac agcaagaagc ggcatcctcg accccttcct cttcaaactc agcgaatcag
    28201 ccaatcaaat ctgccagagc aagtgatatt gccgatgcat ctaatccagc atggacgtgg
    28261 gcaccaggtg tccaaagcaa agtgattgct acatgtatcc aacgtggata tatcgttgaa
    28321 ggaggttaca gattagaaaa agccagaatc gaaaatgggg aaggctatta taatctatat
    28381 gccacttcaa caaaatctgc attgatgaaa ggcattggag aaagtgcttt gccattttac
    28441 atcgtaacca tcaactgtaa aactggatgg ttcggaggaa atgggagcaa ttaattttag
    28501 gcaaatgaaa gaggctgtga gcctgccgtt taacaccgtt tattcgaaaa aggggagtat
    28561 gacacaactg ttgtcatact ccttttttca cctttccaaa ccaaggctca gctattcaag
    28621 tagataacat tatgttatga tagcaaagaa atgtattaag aaaacctttc actatagagg
    28681 gagaaaaaaa tgaacgattt attagcaact atatttacag gtattattat tgatgaaaat
    28741 gaaaaaaact actttgtcca aaaaaacgga caaacctttg gcttaagcaa atcagaaggt
    28801 gaacacaaaa tcggtgaagc agttgaagga ttcggttacc aaaatcaaaa acatgaaaat
    28861 cggatcacta cacaaattcc taaaagccgt atcggtcatt acgcttttgg aatcgttact
    28921 gctacacgaa aagatttagg tgcgtttgtc gatatcggtc ttccagataa agactttgtc
    28981 gtatctcttg atgaattgcc gacaatgaca gagctatggc ctaaaaaagg ggatcgcttg
    29041 atgatttccc ttagagttga tgcaaaagac cgtatttggg gcagtttagc agatgaaaaa
    29101 atattcaaat ctttaagcaa atatggaaca gaagaaatga aaaacaaaga tgtgatagga
    29161 acagcatacc gcttgaaatt aacaggtacg tacgttttaa cggaagattt ctatcttggg
    29221 tttatccatc cttctgaacg atataatgaa cctcgtctag gcgagcagat aaaaggtcga
    29281 gtgattggtg tccgaccaga cggtgtactg aatctttcat tgaagccaag agcatatgaa
    29341 gctatatcag atgatgcaca aatgatttta accattttag aacgttctgc agatcagcaa
    29401 atcaacttta cagataaatc ggatccagaa gaaatcatga aagcttttgg tatcagcaaa
    29461 ggagcattta agcgcgcatt aggtaatctt ttgaaacaag gattgattac acaagaaaac
    29521 ggtgtgacaa aactagtcaa aaaatctaat tgagaatccc ttgcatgttt ttcttaacta
    29581 gcttataata attttaatta acatagtgtt atatcttttt ttatttgtaa ttattataaa
    29641 ttgttggggt tgagtaaatg gtcatgaatg ctatttcggc gatgaaaaaa acaaaacagc
    29701 agctacatga agcggggttt aagctgacac cgcaaagaga agctactctg cttgtgcttt
    29761 tggaaaatga gaaagagcat ttatctgcag aagaaatctt ctttttagtg aaaaaaaaga
    29821 gtccggaaat tggacttgct actgtttatc gaacccttga aatcttgaca gaattgaaaa
    29881 ttgtcgataa agtaagtttt aatgatggat tagcccgtta tgatttgaga aaagaaggcg
    29941 ccaaacattt ccatcatcat ttactatgct tgaactgcgg cacgatcgag gaagtagaag
    30001 aggatctttt acttgaagtg gagcaagtag tagaagaacg ttatcatttt ttagtaaaag
    30061 atcatcggct aacgttccat ggaatctgtc aggaatgcta tgaaaaagaa a
//
LOCUS       DAFBSV010000025        29221 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.026, whole genome shotgun sequence.
ACCESSION   DAFBSV010000025 DAFBSV010000000
VERSION     DAFBSV010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29221
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.026"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..1152
                     /locus_tag="LLB18_001076"
     CDS             <1..1152
                     /locus_tag="LLB18_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HBK5244090.1"
                     /translation="PSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSA
                     EAPKEKVETSGSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKED
                     IENFLAGGPSSAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPT
                     RKAIAKAMVNSKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALT
                     ATVKKYPVLNASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEI
                     NEKAKLAHDGKLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIV
                     NAEGEIVVGRVMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            1160..2566
                     /gene="lpdA"
                     /locus_tag="LLB18_001077"
     CDS             1160..2566
                     /gene="lpdA"
                     /locus_tag="LLB18_001077"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBK5244091.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            2728..3003
                     /locus_tag="LLB18_001078"
     CDS             2728..3003
                     /locus_tag="LLB18_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HBK5244092.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            3009..3776
                     /locus_tag="LLB18_001079"
     CDS             3009..3776
                     /locus_tag="LLB18_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HBK5244093.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            3944..5773
                     /gene="typA"
                     /locus_tag="LLB18_001080"
     CDS             3944..5773
                     /gene="typA"
                     /locus_tag="LLB18_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBK5244094.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            6034..7806
                     /gene="recQ"
                     /locus_tag="LLB18_001081"
     CDS             6034..7806
                     /gene="recQ"
                     /locus_tag="LLB18_001081"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBK5244095.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            7920..8222
                     /locus_tag="LLB18_001082"
     CDS             7920..8222
                     /locus_tag="LLB18_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HBK5244096.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            8225..9388
                     /locus_tag="LLB18_001083"
     CDS             8225..9388
                     /locus_tag="LLB18_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBK5244097.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            9414..12842
                     /locus_tag="LLB18_001084"
     CDS             9414..12842
                     /locus_tag="LLB18_001084"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBK5244098.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            12863..13987
                     /locus_tag="LLB18_001085"
     CDS             12863..13987
                     /locus_tag="LLB18_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244099.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            13977..14414
                     /locus_tag="LLB18_001086"
     CDS             13977..14414
                     /locus_tag="LLB18_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBK5244100.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            14398..14736
                     /locus_tag="LLB18_001087"
     CDS             14398..14736
                     /locus_tag="LLB18_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HBK5244101.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            14855..15415
                     /gene="rsmD"
                     /locus_tag="LLB18_001088"
     CDS             14855..15415
                     /gene="rsmD"
                     /locus_tag="LLB18_001088"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBK5244102.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            15412..15903
                     /gene="coaD"
                     /locus_tag="LLB18_001089"
     CDS             15412..15903
                     /gene="coaD"
                     /locus_tag="LLB18_001089"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBK5244103.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            15893..16936
                     /locus_tag="LLB18_001090"
     CDS             15893..16936
                     /locus_tag="LLB18_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HBK5244104.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            17095..17823
                     /locus_tag="LLB18_001091"
     CDS             17095..17823
                     /locus_tag="LLB18_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBK5244105.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            17939..18184
                     /locus_tag="LLB18_001092"
     CDS             17939..18184
                     /locus_tag="LLB18_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBK5244106.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            18181..18399
                     /locus_tag="LLB18_001093"
     CDS             18181..18399
                     /locus_tag="LLB18_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBK5244107.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            18535..19074
                     /locus_tag="LLB18_001094"
     CDS             18535..19074
                     /locus_tag="LLB18_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HBK5244108.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            19067..21340
                     /locus_tag="LLB18_001095"
     CDS             19067..21340
                     /locus_tag="LLB18_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HBK5244109.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            21378..22424
                     /gene="holA"
                     /locus_tag="LLB18_001096"
     CDS             21378..22424
                     /gene="holA"
                     /locus_tag="LLB18_001096"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBK5244110.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(22513..22767)
                     /locus_tag="LLB18_001097"
     CDS             complement(22513..22767)
                     /locus_tag="LLB18_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBK5244111.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(23167..23436)
                     /locus_tag="LLB18_001098"
     CDS             complement(23167..23436)
                     /locus_tag="LLB18_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244112.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(23906..24361)
                     /locus_tag="LLB18_001099"
     CDS             complement(23906..24361)
                     /locus_tag="LLB18_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HBK5244113.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(24499..26427)
                     /locus_tag="LLB18_001100"
     CDS             complement(24499..26427)
                     /locus_tag="LLB18_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBK5244114.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(26624..27457)
                     /locus_tag="LLB18_001101"
     CDS             complement(26624..27457)
                     /locus_tag="LLB18_001101"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBK5244115.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(27649..28353)
                     /locus_tag="LLB18_001102"
     CDS             complement(27649..28353)
                     /locus_tag="LLB18_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBK5244116.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(28376..29002)
                     /locus_tag="LLB18_001103"
     CDS             complement(28376..29002)
                     /locus_tag="LLB18_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBK5244117.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
BASE COUNT         9699 a         5147 c         6072 g         8303 t
ORIGIN      
        1 ccgtcacctg tcacagggac agttaaaaac gtgattgttc cagaaggcac tgtagcaaat
       61 gttggggatg tattagtaga aatcgatgct cctggacaca atagtgcacc gtcaactagt
      121 gcgccatcag ctgaagcacc aaaagaaaaa gtggaaacat caggttcagc aagtgtcgtt
      181 gaagctgccg atccaaataa acgtgtattg gctatgccat ctgttcgtca atttgcccgt
      241 gaaaaagatg tagatatctc acaagtaact gcaactggaa aaggtggcag agtaacaaaa
      301 gaggacatcg aaaacttctt ggcaggtggt ccaagcagtg caccagcgaa atcagaagcg
      361 ccagaagcgg cagcaccgaa agaagcagct cctgcagcag aaagcaaacc agctgcacca
      421 gcaaaaccat tcaagtccaa cttaggagac ttggaagaac gtgtagcaat gacgccaaca
      481 cgtaaagcta tcgctaaagc aatggtcaac agtaagcata cagctccaca cgtgacattg
      541 catgatgaag tagaagtgtc taaactatgg gataatcgga aacgatttaa agaagttgct
      601 gctgcaaatg gtacgaaact tactttcttg ccatatgtcg tgaaagcttt aacagcgact
      661 gttaagaaat acccagtatt gaatgcatct atcgacgatg caaaccaaga aatcgtttat
      721 aaacattact acaatatcgg tattgcaact gatacggatc acggactata tgtaccaaat
      781 gtgaaagatg cagaccgcaa aggaatgttt gctattgcag acgaaatcaa tgagaaagca
      841 aaattagctc atgacggcaa actatctgca gaagatatgc gcaatggaac aattacgatc
      901 agcaatatcg gatctgtagg tggcggttgg tttacaccag tcatcaacta tccagaagta
      961 gctattttag gtgtaggaac gattgcacaa caaccaatcg taaatgctga aggcgaaatc
     1021 gttgtcggtc gtgtgatgaa actgtcatta agtttcgatc accgtatcgt agatggagca
     1081 actgcgcaac aagcaatgaa taatatcaaa cgtcttttag ctgatccaga gctattaatg
     1141 atggaaggat gataaacaaa tggtagttgg agattttgct gtagaattag atacagttgt
     1201 aattggtgcg ggacctggtg gctatgtagc tgccatccgc gctgctgaaa tgggacaaaa
     1261 agtagcaatc attgaaagag agtatattgg cggtgtttgt ttgaatgtcg gctgtattcc
     1321 ttcaaaagca ctgatagctg caggacacca ttatcaagag tcactagatt ctgaaatgtt
     1381 tggagtaact agtgaaaacg tcaaactaga ttttgcaaaa acacaagaat ggaaagaaaa
     1441 caaagttgtc catacgttga cttctggtgt tggtttccta ttaaaaaaac ataaggttga
     1501 aacaatcgaa ggagaagcgt tcttcgtaga tgatcacaca ctacgcgtca ttcatccaga
     1561 ttcagctcaa acttattcgt tcaataacgc aatcatcgca acaggttccc gtccaatcga
     1621 gattccagga tttaaattcg gaggacgtgt gttagattct actggcggat tagcattgaa
     1681 agaagtacct aagaaatttg tgatcatcgg tggcggtgtg attggtgccg aattgggcgg
     1741 agcgtacgca aacttaggag cagaagtaac gattcttgaa ggctcaccac aaattttacc
     1801 aacttacgaa aaagatctag taaaattagt agaagatgat ttcaagaaaa aaggcgtaac
     1861 agtcgtaacg aatgcaatgg cgaaagaagc agtcgataac ggtgacagcg tgacagtgaa
     1921 atatgcagtg gacgggaaag aagaatccgt tactgctgat tatgtgatgg tcactgtagg
     1981 tcgtcgtccg aatacagatg atatgggctt agaacaagcg ggtgtcgaag taggagaacg
     2041 aggattgatc acggtggata aacaaggacg tacgaacgta cctaacatct atgccatcgg
     2101 tgatatcgtt ccaggggcgg cattagcaca caaagccagt tatgaagcaa aaatcgctgc
     2161 tgaagcaatc tctggcaaaa aagtagctgt agattataaa gcaatgccgg cagtagcctt
     2221 cactgatcct gaattggctt ctgtaggtat gacgatcaaa gaagcaaaag atgctggtat
     2281 cgaagcaaaa gcatataaat tcccattttc agggaacggt cgggcattat cgcttggtaa
     2341 aacagaagga ttcatccgtc tagttacgac gatcgaagat aacgtgctta ttggcgcgca
     2401 aatcggtgga gtcggcgcaa gtgatatggt ctctgaatta gctttagcaa tcgaatcagg
     2461 aatgaatgct gaagatatcg ccttgacgat tcatcctcat ccatctcttg gcgaaatcgt
     2521 catggatgct tcggaattag cattaggttt accaatccat atttgatttg aataatacag
     2581 gcgaaacgca actgaaaaat cagttgcgtt ttgtttttta gaattatcaa taatattatt
     2641 atgtaaactt aaaaatatga caacttcttg gtttattacc acttcctatg ctacactgaa
     2701 gaggaatatg aaataggaga gttgaagatg caagaatatc agtatccact tgatttagat
     2761 tggacaacag acgaaatggt cattgtaatg aagatgtggg aagatctgga acgtgcgaat
     2821 gaaaaaggga taaacaatga agcttttttg aagacttatc agcagtttaa aactgttgtc
     2881 aaatccattg gtgaggaaaa acgattggga cgggaatttg aaaaagcttc cggttattct
     2941 ttatatcgta cagtgcagca agcaaaaaaa aatccaaaca aaactttgag aatgaacggg
     3001 tgagataaat ggaacagatg attgatcata tcaagtcctg gcttgaagaa gctggtgaga
     3061 aaatcaaatc ttctcaacaa acattaacaa tctcgcaaaa atcaaatcga acggatctag
     3121 taacaaatgt cgatcgaaac atccagaatt ttctaatcga aaaaatccat tcctttgatc
     3181 cagaggcgaa aatattggca gaagaagaag ggtgtaatca attatcggat ctcgatggaa
     3241 gagtctttat catcgatcct attgatggca ccttgaattt tgtgattgaa ggggaaaatt
     3301 tttgtattat gctcgctgtt tatgaatccg gcgttggaaa gcttggtttc atttatgacg
     3361 tgatgagaaa tgaacttttt tggggtggaa aaggaatagg cgtgtataaa aatgatgagc
     3421 cattgcctag accagcaaat aaatccttat cggaaggctt acttggtgtg aatagttatc
     3481 ttttcggtca taataaatat ggaatccgag aaattgcgga aagcagcatg gggacacgta
     3541 tgtacggatg cgctggtctt gaactagtgg caatcttgaa aggaaaccac attgcttata
     3601 tttcaaacct tagcccttgg gattatgcag cgggaaatgt cttattggaa gagtttggta
     3661 tggtaacaag cggtcttttt ggtactcctt tgacatttga aaaaagggaa tactatttag
     3721 cagggacttc ttgtgcatat gcagaaatcg cagacctttt gaaaaaagaa ggctgaaaaa
     3781 aaggtagaaa tcattcacaa aaatgataaa aacgagcaaa agattaattt tctcgaaaaa
     3841 atgaaaacat tttactatat ttcatgaaaa aagtctgcta taattagcag tcgagtaaaa
     3901 tttgccctgt cataaagaac caataaaaaa ggagttagtt acattgaatt atagaaacga
     3961 tatccgtaac gtcgcaatta ttgcccacgt tgaccacgga aaaacaacat tagttgatga
     4021 actattaaaa caatcagata cattagacgc acatacgcaa ttgcaagaac gtgcgatgga
     4081 ctcaaatgcg ctagaaaaag aacgtggtat cacgatttta gccaaaaaca cagctgtaga
     4141 ctataaaggt attcgcgtaa acatcatgga tactccagga cacgcggact tcggtggcga
     4201 agtagaacgg atcatgaaaa tggttgacgg cgttgtgttg gtcgtagatg cgtatgaagg
     4261 aacaatgcct caaacacgtt ttgtattgaa aaaagcactg gaacaacata tcacaccaat
     4321 cgttgtcgta aacaagattg acaaaccttc tgctcgtcct gagcatgtcg tagatgaagt
     4381 tcttgaacta ttcatcgaat taggagcaga tgatgatcag ttagactttc ctgtgattta
     4441 tgcatctgca ctaaatggta cgtcaagctt gtcagatgat ccagcagatc aagaaccaac
     4501 catggcacct atttttgata caattattga aaaaatccct gctcctgtcg ataacagcga
     4561 cgaaccatta caattccaag tttcattact tgactacaac gattatgtag gtcgtatcgg
     4621 aatcggacgt gtatttagag gaacaatcaa agtaggagac caagtagcat taattaaatt
     4681 agacggaaca gttaagaaat tccgtgtaac gaaattattt ggtttctttg gactaaaacg
     4741 tctagagatt caagaagcaa aagctggaga cttgattgct gtctcaggta tggaagatat
     4801 ctttgtcggt gaaacagtta ctcctgtgga tcatcaagat gcgttaccta tccttcacat
     4861 tgacgaacca acattgcaaa tgactttctt agttaataat tcaccatttg ccggtcgaga
     4921 aggtaaattc gtaaccgctc gtaagattga agaacgtttg atggcagaac ttcaaacaga
     4981 tgtatcctta cgagttgaac caacaaactc tccagatgca tggacagttt ctggtcgtgg
     5041 agaattgcat ttgtctatct tgattgaaaa catgcgccgt gagggatacg aattgcaagt
     5101 atctcgtcca gaagttattg aaaaagaaat cgacggtgta aaatgcgaac cgtttgaacg
     5161 cgtgcaaatc gatacaccag aagaatatat gggtagtgtt atcgagtcct tgagcttacg
     5221 taaaggtgaa atgcaagata tggtccatac aggaaacgga caaatccgtt tgacattctt
     5281 aacacctgcc cgcggtttga ttggttattc aactgaattc ctttcaatga cacgtggtta
     5341 cggaatcatg aaccatactt ttgaccaata tctgccaatg cttcctggtc aaattggcgg
     5401 acgtcaccaa ggggcgcttg tttcgatcga tacaggaaaa gcaacgactt attctatcat
     5461 gagtatcgaa gaacgcggta cagtcttcgt agaaccaggt acagaagtat atgaaggaat
     5521 gattatcggg gaaaacagcc gtgataatga tttgactgtc aacatcacga aagcaaaaca
     5581 aatgacaaac gtacggtctg ctactaaaga ccaaacatct gtcatcaaaa aaccaaaaca
     5641 attgacgttg gaagaatctt tggaattctt gaatgatgat gaatattgcg aagtaacacc
     5701 agaaagcatt cgcttgagaa aacaaatttt agagaaaaat gctcgtgaaa aagcatctaa
     5761 aaagaaaaaa taatctgtaa aaggatgaag agagaaacca gcttgttata aaaaatagct
     5821 ggtttctttt tttgtccaac tcttttctgt ggagaagtca tctttgtcaa tggacataaa
     5881 ttcagaaaat acgccgaaag acgtttaaaa gacttttaaa aaacttattt ctagagagtt
     5941 tttgtttcat aataagataa tgtttcacga aaggagatca acttgtcctt cgaagaaaat
     6001 cgaagtaaaa tggcaagaga aaggagcggg aagatgaacg acttattaaa acaatacttt
     6061 ggctatgatg agtttagacc tggtcaaaaa gaaattatcc agaaagtcat tgatcaggaa
     6121 aatgtattag gaatcatgcc taccggaagt gggaaatcaa tctgttacca gcttccagct
     6181 ttactattag atgggcttac tgtggttgtg tcccctttaa tctctttgat gaaggatcag
     6241 gtggacgcgg cgaatcaatt aggtataccc gccactttta tcaatagctc gttagatggt
     6301 tacgaaacag ctagacgctt ccaagaaatc gatagacagc agtaccgttt actttatatc
     6361 gctcctgaac gttttatcat gccggatttt atccaagcaa tgaagcgatg gaacgtccgt
     6421 atgatcgcta ttgacgaggc acattgtatc tctcagtggg ggcatgattt ccgcccaagt
     6481 tatttacaga tggcgaacca gctagatcaa ctgccaaatc gtcctgtaat tgttgctttg
     6541 acagctacag cgactgtgca agtagctgct gacataaaaa gacttttaaa aattccagaa
     6601 aacaaccata ttcagactgg ttttgaacga gaaaatctac gatttcaagt aattaaagat
     6661 caaaaaaaag aacaatatct aatcgaatat ttaaagatca acaaaaatca atctggtatc
     6721 atttatgcag caacgagaaa agaagtagac cgtctctatc atttgcttaa aaaattcgat
     6781 ttttccgtgg gtagatatca tggtggtcta aatgagaatg agcgaacaga aatgcaagaa
     6841 gcctttttat acgatcgctt gcagctgatt gtagcgacaa atgcatttgg tatgggtata
     6901 aataaaagca atgtccgttt tgttatccat tatcaaattc ctggctctct agaagcatac
     6961 tatcaggaag ctggtcgggc gggaagagat ggtctttcca gtgaagccat cctgcttttc
     7021 tctcctcaag atatccaagt ccaaaagttt tttatccagc agtcccaaag agaagaaggg
     7081 caaaagcaaa aagaatatga aaaattaaaa gcgatgacag aatacgtgta tattgagtcc
     7141 tgtcttcagc aatacatcct aaactatttt ggcgagacaa gcagtccgtg caaccgttgt
     7201 ggtaactgtt tagatgacag agaaatagta gaagtaacga cagaagcaca gatggttctt
     7261 tcttgcttaa aacgtatggg tgagaactat ggtaaacaaa tgctgatgaa agtcttagca
     7321 ggatcgaaag aacaaaagct gcaagcttta ggttttggac atttatctac ctatggactg
     7381 atgaaaaacc aatcgcaaaa agaaacgatg cagttaattg aatatttgat atcgaatggc
     7441 tatcttctga ccatcaatgg tgagtatcct gttttgaaag taacagaaag agggatacaa
     7501 gtattgaaag gacaagaatc tgtttatcga aaggaaccca agaaagtcca gcagctatcg
     7561 gatgaagaaa ccgatacact atttgaagtg ctgcgggaac tgcgaacgga tctagcatca
     7621 gaagcaggcg ttcccccgta tgtcgtattt tcagattcca cattgaaaga aatgagccga
     7681 atacgtccat caagcagatt ggagatgctt cagataaaag gagttggcca aagcaagctt
     7741 gataaatatg gcgaagcctt tttatctcgg ataaaaaatg cggactctaa cgttctggat
     7801 aagtagaaag aacgaatacg taaaaatgaa taaaaacaac tggttaaatc tgtttttttt
     7861 gctccttatg aaaatcaaat atgttataat taaggaatta gaatgggagg taagcacaga
     7921 tggattcttt gtcgaaaaaa cttgcgatcc aagtattaaa tgatgaagca gaacggatca
     7981 aacgattaat ccgaaatcaa aacaacagtc tctgtatctc acaatgcaaa gccttcgaag
     8041 aagtggtaga tacacagatg tacggctttt cccggcaagt cggttttgct gtccgtatag
     8101 gagtaatcgg aaagaacgag ggccagctga tgttaagtga gctagaacga gaattgaatc
     8161 agttatatag tgaggtttac caagaaattt atgataaaaa agaagttggc aaggaggaat
     8221 agacttgcct aagaaagtga aaaaaaggca tctattagac tatagcatct tgattcccta
     8281 tttaatttta tgtgtattgg gattgatcat ggtatatagt tctacgtcgt atctattatt
     8341 agaaaacgga caaaatccgt ccgcatcagt cattaaccag agtatttttt gggtgcttag
     8401 cttgattgct atcgcactac tttataaaat gaaaacagat gttttgaaaa accagcgttt
     8461 gatcatggca gccatcgcag ttttgacgat tttgctgctg attgttgtgt tttttggtaa
     8521 ggagatcaat ggggcgaaag gttggctgca aattgcagga ttctcgatcc aacctgccga
     8581 atacctaaaa atcatttcta tctggtacct gtctctgact ttatctaaaa gacaaaacag
     8641 tgtacaaaaa gattttcttg ggactgtgaa acgtccactt gcaatggtta tcggacttac
     8701 tgcattagtc gctattcttc ccgattttgg taatgcggca gttatctttt tgattatttt
     8761 ggttctgctt ttagccagcg gagtcaatta tgtgtatact ttgattgtag gagtaggagg
     8821 cttttgtcta agtactttta cgatctggct gatcaatatc acaaacggaa agatcttacc
     8881 cggacgttta cagtatatct ataatcgatt tgctatttac caaaatcctt tctcagacga
     8941 attaaataaa gggcatcaac tagtcaacgg ctactatgcc atgttcaacg gaggactatt
     9001 tggcagggga ttaggtaaca gtatccagaa aaaaggattt ttacaagaag cacaaaccga
     9061 ttttatttat gcaatcgtag tggaagaact gggagtgatt atggggattt tgatattagc
     9121 gttgctattc tttatgattg tgcgcattgt ccttgtaggt atccgttcaa aagatccgtt
     9181 caattcgctt ttgtgcattg ggatcggcgc aatgtttttg atccaagtat ttgtcaatct
     9241 tggaggaatt actggcgtta ttcctttgac agggatcacg ttcccatttt taagtcaagg
     9301 aggctccagt ttgctgatgc tttcgatttg tgtcggcttt gtcctcaaca tcagtgcgga
     9361 tgaaaaacgc aagagcttag gtttataata aaaaaagatg taggagtggt tcgatgaaaa
     9421 aagttttagt tgctaacagg ggtgaaatcg ctgtacgtgt atttcgtgct tgtacagaat
     9481 taggaattaa aactgttgga atctatgcag aagaagatga atattccgta caccgtttca
     9541 aagcggatga agcatattta gtaggacaag gaaaaaaacc gattgatgcg tatctagata
     9601 ttgaagggat catttctatc gcgaaagaat gcggagctga cgctattcat ccgggttacg
     9661 gtcttttgtc ggaaaacttg aattttgcgc aacggtgcga agaagaaggc atcatttttg
     9721 ttggacccaa actgcatcat ttagatattt ttggagataa aatcaaagca aaagctgcag
     9781 ctatcgaagc ggggattgct tcgattccag gcacagatgg accaatcgct tctatagacg
     9841 atgccttgga gtttgcgaaa caatacggtt atccgattat gatcaaggca gctctaggcg
     9901 gcggcggacg cggcatgcgt gtagctcacg atgaaaagag tgcaagagag ggctacgaac
     9961 gtgcgaaaag cgaagcaaaa gcagcctttg gtagtgatga agtgtatgtt gaaaaataca
    10021 tcgctaatcc taagcatatc gaagtacaga ttctcgggga tacgcatgga aacgtcatcc
    10081 atctttttga aagagattgt tctgttcagc gccgtcacca aaaagtagta gaagtagcgc
    10141 cttgtgtctc tatgaatgaa cagcaacgtc aaaaaatctg ccaggcagct gtccaattga
    10201 tgaaatatgt cgggtatgtc aacgcaggta cagtagaatt tcttgttgaa ggagatgatt
    10261 tttactttat cgaagtcaac cctcgcgtcc aagtggaaca tacgatcaca gaaatgatta
    10321 cagatattga tatcgtaaca acgcaactgt tgattgctca aggtttggat ctgcataaag
    10381 aaatcggatt gcctcagcaa gaaggaatta aattaaatgg ttcagccatt caatgccgaa
    10441 tcactacaga agacccgttg aataactttt taccagacac agggaaaatc gatacgtatc
    10501 gttcacctgg tggttttggc gtacgtctgg atgtcggaaa tgcttacgcg ggctatgtag
    10561 tgacaccgta ttttgattca ttgctagtaa aagtatgtac gcatggtgct acctttgaaa
    10621 cagccattca gaaaatggaa cgttgcttga aagaatttag aatccgtgga gtgaaaacaa
    10681 acattccatt tatgctcaat gtcatcacac atcctgaatt ccaatcagga aatgcaaaaa
    10741 caaccttcat tgatagtaca gcaacattat ttgaatttcc tcgactacga gaccgcggaa
    10801 acaaaacgat gaaatatatc ggtgaaatta ctgtgaatgg ttttccaggt atcgaaagtg
    10861 gcgaaaaacc attttatgaa gaaccacgta tgcctaaaga tctaatcaca agaactgatt
    10921 acgtaacggc taagaatgta ttagatgcga agggtgccga tgctttggtc gaatggatca
    10981 aaggacagga aaatttgttg ttgacggata cgacatttag agacgcccat caaagtctgc
    11041 tagcaactcg tgttcggaca aaggatttca agcagattgc acgtttgact ggagaaggtc
    11101 ttcctgaact cttttcaagt gagatgtggg ggggagcaac atttgatgtg gcttaccgct
    11161 ttttgaatga agatccttgg caacggttga gaaaaattcg ttctttaatg cctaatacgt
    11221 tgctgcaaat gcttttcaga ggttcaaatg ccgttgggta ttctaattat cctgacaatg
    11281 tattggtgga atttgtcaaa gaagcagcag cgcaaggaat cgatgtattt cgaatctttg
    11341 atagtttgaa ctggactcca caaatggaaa aaagtatcca agctgtacgg gatactggta
    11401 aaatcgcaga ggcagctatt tgctatactg gcgatatcaa cgatccaagt cgggcaaaat
    11461 acaatgttca gtattataaa gacatggcaa aggaactaga acaactgggt gcgcatatca
    11521 ttgcaatcaa agatatggct gggctgctta aaccgcaggc agcttatcgt ttgattagtg
    11581 aattgaaaga aacgacagat ctgccaatcc atctgcatac tcatgatacc agcgggaatg
    11641 gaatcatcac ttattctgct gcttcaaaag caggagtaga catcgttgac gtggcaatga
    11701 gtgcaatgag tgggaatact agtcagccta gcatgagcag cttgtattat gcactggtca
    11761 atggtccacg gctgccagaa atcacgattg aaaatgcaca gaaattaaac cattattggg
    11821 aagatgtgcg catgtattac aaaccgtttg aaaacggctt gaatgctcct gaaacagaag
    11881 tatatatgca tgaaatgcca ggaggacagt attcgaatct acagcaacag gcaaaagctg
    11941 tcggattagg tcatcgctgg gatgaaatca aacaaatgta tcatactgtc aacttgatgt
    12001 ttggcgatat cgttaaagta actccatcat ctaaagtagt tggagatatg gcactattta
    12061 tggtccaaaa tgatcttaca gaagaagata tttatgaaaa aggcgaaaca ctaagtttcc
    12121 ctgaatctgt tgtgactttc ttccaaggag aactagggca acccgttggc ggatttccta
    12181 aaaaattgca aaagattatt cttaaaggca gacctgcatt gaatgaacgt ccaggtcttt
    12241 tggctgaatc agtcgacttc aacgaagtaa aaaaagaatt ggcagaaaaa attggctatg
    12301 aaccaaaaca agacgaagta ttaagctatt tgatgtatcc gcaagtcttt ttggactatc
    12361 aaaaagcata taatcaattt ggcgatgtta cattactgga cacaccaaca tttttccaag
    12421 gtatacgttt gggtgaaaca atcaatgtac aaatcgaacg cggaaaaacg cttatcattc
    12481 gtttagatga aatcggagaa cccgatatcg aagggaatcg cgtactgttc ttcaatttga
    12541 atggacaaag acgtgaaatc actatcaaag ataattcgat catcagtacg gtccaaaccc
    12601 gattgaaagc tgaaccgaca aaccgagaac aaattggagc aacgatgtct ggttctgttt
    12661 tggatgtatt agtgaaaaaa ggcgataacg ttaaaaaagg tgatacgttg atgattactg
    12721 aagcgatgaa aatggaaacg gccatcgaag cacgttttga cggagaagtc gcacatgtat
    12781 atgtgtcttc aggagacact atttcgtctg gtgacctttt gattgaagtg actgagaaat
    12841 aataagcgaa aggtggggaa acatgaaaag actgggtttg ttttggctga ttctgctatt
    12901 agttattgtg gcattctaca tggaaccagt cttgtttccg ccaaaacttg aagtgaagga
    12961 aaactctgat caacaaatat caaaccaaat gacaacgtgg aaataccagg agcttaaagc
    13021 aactggtttt tctacttata tcggaaaacc gatcgatcag ctggaaaagg attttggcca
    13081 agcctatgat cgattaacta gcggatttgg ttttgaaaca agatattatg aaaataaagc
    13141 tagtcatctc acatttgaag cgaacatcca agacagcaga gtcacaactg ttaaagtact
    13201 gcaaacaggg cctgctgata tcgcgccgtt ttatttaggg atgacgatgc aagatcttac
    13261 gaaaatcact actatctata ctaatttcac ttttgagtac catgatacag aagttggaat
    13321 cgaactaatg gaagaggata tgaattatcg tccgctaatt gcttttgata acgacacttt
    13381 tgctatttta ttttttgatc aaacaacaaa cggcctattt tcagttgtgt atttagataa
    13441 agatagtctt ttgaaactat tgccatatca agtgtttggt gaaggccttc cacattatca
    13501 agcagataaa tcggctgatt gggaatcaat caatcgcgtt aaagaacgaa aaagtacgac
    13561 tttattaaat atgcttagaa gagaagacga acttcccata tacaatcaaa cacttgcctt
    13621 tcaaaaccac agtcagctgc tactacatga ttttttgaca aggcctgagg aaatattgtc
    13681 agaggaacgt atggctgatt ggcaaaaatc gctaggcagt gctcaaacga cagtgaaatt
    13741 ctcactgacg aatgatgaat tggagaagtt aatcagtaaa caaaaattag aaaatactag
    13801 tgggctattt attcatccgg cgattgacgc tactttttcg tttttatatt ggtacagcga
    13861 tccttacaac catgaccgtt tcatggaccc gggaacggat tctgtaggca ttgctttttc
    13921 taaagaaaat atgttagtct tattgcaaga agaaaacgga gaaagtagtg atagcagtga
    13981 tcgttaacga agagctgttt caactggagg atcaatgcct ccaagtcgct gaaatgataa
    14041 aaaagagtaa aacgatggct tcttatcttg aacataaaca gtcaatggaa gaatctgcaa
    14101 aagtttgcca gttgaaagaa gcgttcttgt ctaagaaaga agcatttgaa aatgtagcgg
    14161 catatggtga gtatgcacct gattatcgtg aaaaaaaacg agctgttcga aaagcaaaaa
    14221 gacagcttga tatggatgag catgttgcag ctttccgata tagtgaaaca cagctgcaaa
    14281 gtctgttgga tcaaattgtc caagtacttg ccgaagaagt ttctaatgaa atcaaagtag
    14341 atgcaggtag cccgtttttt gaaacgaaaa aacactttgg atgcggaggt aattgtcatg
    14401 caattagaca atagtgaatt tgaaataaca aaacgacgcg ggctgatcgt atgggtctac
    14461 agcttaaaac aattaaagaa tctgaaaaag ttcggcttgt tgcattatgt ctcaagaaga
    14521 atgaaatatg tcgtgcttta cttaaatgaa gagacattgg aagaaacaga agaacgaatc
    14581 cgtaaattac attttgttcg aaacgtagaa cgttcttacc gaccggatat cgaaatgaat
    14641 tttgccgaaa aaataggaaa caaaacagta ttaaaagacg aaggtttcga aattgaagag
    14701 ctaaatacag aaatccgatt agctgaacat ctttaaaaat ctcttatgag cagtttttaa
    14761 ataaaaaata acttggataa cgatcgattt ttgatcattg tccaagtatt tttttggtat
    14821 actagtacca gtaccatttc taaggagtga gtagatgcgg ataatatcag gaaattatgg
    14881 cgggcgccgt ttaaaaagtt tagcaggggc gaacaccaga ccaactacag ataaagtaaa
    14941 agaatccata ttcaatatga ttggaccata ttttgatgga gagacagtat tggatctgtt
    15001 tgcaggaagc ggtggtttag ctatcgaagc agtatctaga ggctgcagtc atgcggtatg
    15061 cgtagacaaa aattaccaag cgctaaaaat catcaaagaa aacatcgaaa ttacgaaaga
    15121 accagagaaa tttaccacaa taaaacttga tgcggacaaa gcaatcgaac ggctagcagc
    15181 ggagaaacaa caattcgact acttgtttct tgatccgcca tatgcaaaac aaaaaataat
    15241 cgatcaaatc cataaaatgg aagaactggg acttttttct aaaaccgcag ttatcgtatg
    15301 cgaaacggat aaaacagtcg aattgccaga aactgtggct ggattccatc aaataagaaa
    15361 acagatttat ggcataacgg ccgtaactat ctatagaaaa gagggaaatc aatgaaacgt
    15421 gcattattcc caggaagttt tgatcctttt acaaaaggtc acttagatac ggtggaacgt
    15481 gcggctaaat tattcgatga ggtagtaatt ggtgttttta tcaatacttc aaagaaaagt
    15541 ttgtttcccc cagaagaaag aatgacattg atcacaaaag ctgtttctca tcttcctaat
    15601 gtaaaagtca tgcatcaaga aaatcaattg acggtagaaa cagcaaaaga gattggtgca
    15661 gatgcgttga tcagaggcat acgaagtatc aaagactttg aatatgaacg agagattgct
    15721 cagatgaatc atcatctata tgatgaattg gaaactgtct tcttattagc aaaaccagaa
    15781 tatagtcacg tgagttccag tattttaaaa gaagtactgc actttggcgg agatgtgagc
    15841 agctacttac cgccagtgat caacgaagct ttagctggaa agcgtgaatc aaatgaaagc
    15901 taaacaatgg ttgaaaacag tactgattat catatttgga atgttgatca ttggatttgt
    15961 agtagttccc ttgccgtatt atgtagaatc accgggagcc acgatcgatc tgaaagaact
    16021 aattacggtc aatgataagg aagataaagg ttctgggtct ttctctctta cctctgttgg
    16081 tatcaggcaa gctacaggtt tcttagcttt aaaagctaaa atgacccctt ttgaagaatt
    16141 gatcagtgaa gaagaattga ctggtggggc gacaaatgaa gaatataatc aaatgcaaca
    16201 gtattatatg gattcttccc aaaatgcagc aatcgaacaa gcgttaaaac ttgcagacaa
    16261 gccttataaa atggaattca aaggcgtata tgtcatgagt gtagagaaaa catcgaattt
    16321 ctttggcaag ctttcagttg gagatacagt aacaaaagta gacgggaaaa gctttcaaag
    16381 tacagaagca tttatggatt atgtaaaaag ccaaaaagtt ggacaaacaa tcgaaatcag
    16441 ttatttgcat aatggtgaag aaaaaacagc ttctggtgat ctgatcgagt taccaacaga
    16501 taaaaaggca ggaataggta tcacgcttac tgaccatacc gagatcgaat cagatacaga
    16561 tgttcgtatt aattctggct ctatcggtgg gccatcagcg ggattgatgt tcactttaga
    16621 aatctatgaa caagtcactg gtaaaaactt gcgacatggt aagcaaattg caggaactgg
    16681 aacgatcaac agtgaaggag aagttggccg aatcggagga atcgataaaa aagtggcaag
    16741 tgcggataaa gctggcgtag agattttctt tgcaccagat gatacgattt cagacgatgt
    16801 taagaaagaa tatcctgaaa taaaaaccaa ctacgaagaa gcaaaagctg ccgctaaaaa
    16861 attgaattcc tcaatgaaaa tcgtaccagt aaaaacagta caagaagcgc ttgactatct
    16921 agagaaaatg aaatgaaact aaataattaa agaggggttg tgacacgagt tctgtcacaa
    16981 cccctctttt tcgtcaaaaa tcttcacgat aaaaataaaa acaaaagaaa aaattgacgt
    17041 aattagatgt tgaagggacg attttgccag agctcactgt ttcttcaatt ttaaatgaaa
    17101 ggagtaatga atgattttta ctggtcattc tttgaaaaaa gaacaatgat agaaaaaatc
    17161 agcaagaaaa tactagcttc acccaaattg atcatttgga tgtctatgat agttcttatc
    17221 ttttgtatcg caagtggttt tttattatca aatttgctat tttatagaga aacagaagag
    17281 actgctgcaa aagaaatact ttcttcgttt agttccagtg gagaagatcc atcagctgaa
    17341 ggaaacgatg tagaagagga tgctcgtcca aaggtcatgt acaccgatat caaaggaagt
    17401 gtgaaggagc ctggtatcta ttccttttct tcagaagaac gggtctatga tgtactaaag
    17461 cgtgcaggtg gattattaga agaagcggat agcgatcgaa tcaacttttc tgcgaagata
    17521 gaagatcagc aagtcctata tatccctgct gtaggtgaag agctgccaga acatcttgat
    17581 cagttggcat cctcggaagg aaaacagcct acagcagatt ccgagcctcc caaaataaat
    17641 atcaatacag ccactccatc agaacttcag cagattcctg ggatcggatc agtcaaagcg
    17701 caagaaatca ttcgatttag agaagaaaac ggatccttcc agaaagtgga agacctgcag
    17761 gagatttctg gtatcggtga aaagacagtt gaaaaactaa aaaacttcgt tacaattaaa
    17821 tagaatgatt caaaatcgac tggcacgagc aataaatgga cgctaatgga tactaagaat
    17881 aatccaattc taagagcttg gcaggacgag gaggtagtat ttttggatag gaaatagctt
    17941 gattgttcgc aaagaaacat taaaaaaacc aatgctgaat gtctatctcc aaaataaaat
    18001 atctgggatt catattatga atacggctgt cagcggcaat aacagtcaag ctctacgaga
    18061 acgctttgcc aaagatgtac ttagctatac agcagataaa gtatttattc tcattgggac
    18121 gaatgatcta gcagagcata aacaactttc taaagaaacg taccaaaaaa tctgcagtgg
    18181 atgatagttc agctgaaaaa agactatagt tctgatcatg ctttctttat cacgccacca
    18241 gcagtcgatg agacaaaaca aaaatatcgg aataacaagt tgatcaaaga atatatctct
    18301 gttctcacag aagtagcaaa acgccatgat tgtgaagtat cgatttttat acggaatttc
    18361 ttgaacaaat ggattcgaag aatttttata atgggctaat ggatgacgga cttcatttcg
    18421 gcagtgaagg gtaggatctt ttgtcagaca ggatgattcg ttatatttaa agaatatttt
    18481 gtttaagcaa tgagtacttt ttaatcaact tgaaaaaacg gaggaatata aaacatgtta
    18541 gaaaaatctt caaaagcatg cgatacgaat aaagaaaaag ttactgataa gtcacataat
    18601 gaacgcattc cttgggacca gtactttatg gctcaggcag tactgttatc tttacgtagt
    18661 acgtgtacac gtttagaagt aggagcgaca ctcgttcgag aaaaaaggat cattgctggc
    18721 ggctataatg gagcagtcag tggagatgtc cactgcatag atgaagggtg ttacgtcgtg
    18781 gatggacact gcttgcgaac gatccatgca gagatgaatg cactcctaca gtgtgcaaaa
    18841 cttggtatcc cgacggaagg ttcagaaatc tatgtcacac attttccatg tttggcctgt
    18901 acaaaggctt tgttgcaagc tggtgtgaaa gggatcaatt atctccatga ctatcgaaat
    18961 gatccttatg cccaagcgtt gatcgaacaa ttaggtgtat ctgtacacca agttgcttta
    19021 gactcacagc atttttcaaa acttcaaaat gaattaacag gaaaacatgt ctagcgtttt
    19081 agaaaggcat gttcgaaatc ggttgatttt tccggcaatt acgtcgatga ttatctgttt
    19141 gttgtattac actgacaatt ggggttatcg tttgcttctt gccggaattt ttttatggtt
    19201 ttcgctaaaa gaaggacgtt ttatcgcgta cttgtgtatt ttgtgtagca taacggtatc
    19261 catttcttat aggctacaag agtattcatt tttagaggaa aaaacaacat ctgcgcaaat
    19321 tactgtattt acagatacga ttcgtgcaaa tggtaatttt ttgacaatgg aaggaaggtt
    19381 atcagagaat aaacaaaagc tccagctttc ttatcaagta aacacagaag cagaattgaa
    19441 aacatggctt aacttccgag gaaagggaat agaattgact gctgaaggcg agttcatctc
    19501 tccagcaaaa aagcggaatc tttataattt tgaccaagaa gcttacttca ggaaccatag
    19561 aatttctgga cggttccaaa ttcaaaagat tgaacagatc accatgcaaa atcactggcg
    19621 aaactggctt cagagaaaaa gaggatcttt tatctccttt gtccaatctg aatttccgca
    19681 aaaaacaagt gtatatatta attctttatt atggggctat aaagatgcag gattcagaga
    19741 accagaagaa atttttaggg agagtggttt gctgcatctg ttcagtctat cgggtctaca
    19801 catccaattt tatttagggt ggctgtatta tttatttcga cgtatcggat ggccactaca
    19861 cgtcagtatt attccgttga gtctactaac tatctgttat gtttctattg caggaagttc
    19921 tatttctgtt ttgcgtgcta gtttgctgtt tttattgcga ttgctagtca aattgctgaa
    19981 taagcattat tccaccatgg acttatttgc agttgtcttt tggcttcttt tactatttga
    20041 tcctcgattt ctttttcatg cgggtggaca gcttagtttt ttcatgagtt ttttgtttat
    20101 cctgatttct tttgatggag attggttgaa aaaaacggcc tctcacgtcc tgtttactat
    20161 gatcacgatg ccgttgattg tatggcattt ttatgagtgg cctattttag gtagtctttt
    20221 tacattactg attgcaccgg tattcaagtt tctttttctt cctggtgtgt tatttctcac
    20281 actcttcaat cgctggctgc cggaaacttt acttttgttg atagaagagg gattaatctt
    20341 atttgagcga ataatcgatt tttcttcagg gtcgtctctc attataggac gtttgcccct
    20401 tgtgctatct gggatgtata ttttcggatt actgatttgt atggataggt tgaaagaaca
    20461 acctgtgaaa cacttgtttt atgttggtct tttttctttt atttttttga ctttgccatt
    20521 tttacgcttt tcttcaacga tcgcttttat cgatgtcggt caaggagaca gtatcttttt
    20581 gcaaagtcct tttcgaaaag aaacgatttt gatcgatact ggaggtcagt tacactttga
    20641 aagagaaaag tgggcgcaag gtatgatacg tcctcctgct gaaagaaata tcgttccata
    20701 tctaaaaggt caggggataa gtgtaatcga taaactcatc ttgacacacg acgatacgga
    20761 tcatgtggga gaattaccca cgttatctca gcattttact atcaaaaaaa tttatatcgg
    20821 ttggggcgct ggacgaaatg agccattaca aaggcattta tctgaagctc aaaaaaatgg
    20881 tactgagatc attgaaatca aacatgggga caggatcagc ggttattatg atctttatgt
    20941 attgactcct tttgaaaagg gagagggaag aaatgaagat tcgattggtc tatggatgga
    21001 atataacaat aggcgctttt tatttttagg agatttgaat caagcaatgg aaaaacaatt
    21061 gcttttgatt tatcctaatc tgaaagccga tgtagtcaaa ttaggtcatc acggtagccg
    21121 tacgtcaagt aacacagatt ttctttccca tattgaagca aaacatggga ttatatcctg
    21181 cggcgtaaat aatcgttatg gtcacccgca cagcgaagta ttggagacac tagaagaaaa
    21241 tcagataaaa acatggcgaa cggatcaaca aggaatgatc acctatcgct ggcatccagt
    21301 ttttcatcct catgggctag tggaaacaat gatagactag taattctcat ctgctcatgg
    21361 taggataatt tttgaaagtg gtgagtaatt tgagtataca agcagagtta caaaaaatac
    21421 gtaaagaaaa acttgcatct tgttacttga ttttaggaac agaaaagttt ctccaagatc
    21481 aagttcggac agaaattgtc aaaaaaatcc aattagaggg cgaagatgac ttaaattttt
    21541 taagttttga catggaaaat gcaagtttag atgaggtagt agctgaagca gagacgttgc
    21601 cgtttttcgg agatcaacgg ttagtattcg tagagaatcc ttatttttta acaggtgaaa
    21661 aagtaaacaa tggaatcgaa caaaatactg atttattgac ggcttatttg aaagaaccat
    21721 tagaatcgac tgtattagta ttctttgcgc catatgaaaa gttggatgaa cggaaaaaag
    21781 taacgaaaca attgaaaaaa acagcaatta tcatcaatgt ccaacagttg aatgaaaaag
    21841 aagtacgtca atatctgatg aataccttag agaattcctc aatcaaaatg gaacgaagtg
    21901 caattgattt attcttgagg ttgaccgact tagatttatc caaaatgatg agagagttac
    21961 agaaattggt cctttatgga caaaatcaac agcaaatcac ggtaagagaa gtagaagaat
    22021 tagttcctaa aacgttagaa cataatattt ttgacatgac ccaatatatt ttaaaaggga
    22081 agacggaaca agctttgcgt ttatacgaag atttagttat gcaaggggaa gaaacaatca
    22141 aaattaatgc gattttgctt tctcaattac gtttattttt acagacaaaa tttcttgtaa
    22201 agattggtta tcagcaggca aatattgctg aaacattgaa aatccatcca tatcgtgtaa
    22261 aacttgccat gcaggaagta aaaaaattcg atgaacattt gctggtacag ttgtttgatc
    22321 aattagttga gatggattat caaatcaaaa cgggacaaat cgaaaaagaa ttaagttttc
    22381 aactattcgt tttgcgcaca gggcagttgt taagaaatcg ataagaagaa agacgagggc
    22441 aaagcatgcg ggaaggtcgt ttgtttttgt cctttttttg acaaataaaa aaatcggccg
    22501 aagccgattc ttttatttag cgattttttt gcttaaacga gatttgtcgc ggttagcttt
    22561 gtttttgtgg attagacctt ttgattcagc catatcaata gctttaacag cttctttata
    22621 taacgcatct acgttgtcag cacctgaagc tacagcatct tcaaattttt tgattgcagt
    22681 acgcatagcg cttgtttgag atgaattttt cacattagcg ttttcgcttg tacgaacacg
    22741 tttgattgca gattcaatgt ttggcattag tttcacctcc gataacttaa gttcttacgc
    22801 gtgttaccgc ataattcaac attcattatt atacctaaag gcagcgtgct ttgcaatatg
    22861 aacatgacaa gtttttttcc ttaacagtct tttattagga ttttttttca gtaaaaacgg
    22921 atagtacaag ctgaaaaaaa tcaaaaagac gctattgtgg gaggcaatag cgtcaaacca
    22981 aactagattt ttatttatct atttaaacaa agtttgaatg ggaatgtttg gtactaagtt
    23041 attatataac aaagagaacc gtttgcaaag ttttttttga aaagggatac gattccctgt
    23101 tgttctttgt ttttctatta agaaactgca gttattttat aaccagtatc ctttgatcag
    23161 taaaggctat tctggtgtac cgattatttt aatgtattca tcgatatttt ttatcaacat
    23221 tttttttatg accaactggt tccgacggtt ccatttgcca cttacttcca gcacatattt
    23281 atttaggggc aaacgtaaga tatattttgc caaatagcga tctttaagca ggccattgat
    23341 cacacggtcc tcaagctgca agttgatccc agtcagcatc attggctgtt cttgtaaaac
    23401 gtacgtatca attaaaagac cttcaaaagt ttccacaagc gtcttccttt cttttcaaag
    23461 taacctgaaa acaggcacta attcttccat tttgatattc gttgaagtgg atgcgatcat
    23521 tctttctttt gtccactgta atctagtata acaaaaaaga gcagaagagc caaaaagaaa
    23581 aaagagcatc gaattctata ggaagtctca ttggcacggc ctaaattatt acaaaacatt
    23641 gattaaaaaa agcccctgca tcgcaggagc atcccctata tcgttttaat aggtcaatca
    23701 aaaagcagta tcaaacacat tttgtatcaa atcaggaaat aatagataag ctaagcccag
    23761 aatcaaaagt accgctagaa gaaaccagcc gattgttcct atgaaatact ttaatttttc
    23821 gaacattgta tcacctcgtt gtcagtatat cacggatcag taaattgggg gtgttaagaa
    23881 tctcctaaaa tagacaaaat ttgttctatt ttcctaaagc aaatacttgt aagatacagt
    23941 aagtgatacc agaagcaatg accggtccgg cggcgattcc tcttaagaag acaacaccta
    24001 aaatcgtgcc gaaaacaagt gcaacagtga tttgtggatc agaagcaatc aatcctacac
    24061 ccttggaaga taagacagcc actagcccac cgcaaaaaac agctacccag ccaatagggg
    24121 atttaaaggc ttctaataga tcacgtagac cgatttctcc tgttgcgata gggattagaa
    24181 tagccgctgt gatgatcgtc accccaatat tgattccttt gccttgaagc caagggaaaa
    24241 aggaacggga ggctggtatg agcttcataa tcaaaacaaa agctgccgct atcatcagac
    24301 tttgattttt agctaaaatt gctacaagta aaataattcc taaaaaaagc caactttcca
    24361 tgaaatatat tcctcacttt cttcgaaaca atcataacat gtttttagaa agttacaaaa
    24421 gtaggaattc atccttcaag acctattcat aagctgtttt tttcataaaa taaacaaaat
    24481 cataaaaaaa cactttgctt atttgacaga agacagccgc gctttgtata gtggacaaga
    24541 cttacatttt tttgaagaat cagaaagatc aggtaaaggt cttagtaaac gcaagccatt
    24601 cagaataacc aatattgtgc ttccttcgtg tcctacaact ccaagaggta gatttaaaaa
    24661 ttgcaggaag ttagaagcaa tcaacaagag aataacaaga atcgaaaaaa taatattttg
    24721 tttgatgatc cgccgcattt ttaaagatag ccgatgactg tagacaaatt tatttaagtc
    24781 gcttttcatt aagacgatgt ctgcgatatc catagcggca tctgtccctt gccccatagc
    24841 gacacctaaa gaagcggctg ctaaagcagg cgcatcattg actccatcac caaccatcgc
    24901 atttacttgg taaagttcat tctctttttt gactagttgt gttttttctt ccggagtaca
    24961 gcttgcatag taatgttcaa tccctacttg ttcagcaatg gcctttgctg tgccagaatg
    25021 gtcgccggtt atcatacttg tatggatgtt ttgggattta aagtaggaaa ttacttgttg
    25081 ggtatttgct tttggaatat ctagcagacc taaaacagca attaactgct gatctttaga
    25141 aagataaatc acggttttgc cttgattttc caaacgttcg atcatttccg caatctcttt
    25201 gctgattatc atcgtctcag gatcatatgc gtgcttgcca actttccatt gcgcacctaa
    25261 ataggtagtt tgtaatccaa aaccagtaat ttcttctatt ggtaagtatt ggatttcttc
    25321 aggtattgtg caatcgaaat attgcaaaat cgcatgagca agtggatgcg tcgttttttg
    25381 ttccatagca acaagaagtt gttgtgccaa atccttttca tcaaagaaaa agctgtcagt
    25441 tacaactggt tttcctttag tgagcgttcc tgttttatca aaggcaatcg cttttaattc
    25501 agaaagcttt tctaaatgga taccgccttt gattaaaatc ccattttttg cagaatttga
    25561 aagagcagct agagaagctg gtgtagcaga tgcgacaagc gcacaaggag aagccacaac
    25621 taataatacc attcctcgat aaaagctttc atcccaactc caacctagga aaaagtgggg
    25681 gagaaggatc attagaggaa cagcaagcaa aatcaatttt acataattat tttcgattcg
    25741 ttcgataaat gaagctgttt gagttggcgt attctgcgct tcttctacta attggataat
    25801 cttagcaaag acagtttcgg aactcgtttt tgttactcga atcgtgatgg gatttccttg
    25861 attcagcgtt cctgcataca tctcatcgcc taaatatttt tctacaggca cagattcacc
    25921 gcttaatgca gactcatcga tcgttgcctg tgtgctttct aaaaagccat ctatcggaac
    25981 agctgctcct ttagcgacaa ataccaagtt atccaccttt agttgagaaa catctacttc
    26041 ttgcatttgt ccattttctt ttaataattg ggctttttgt ggttgaagat tcatcaaagc
    26101 agtaatttct ttttgacttt tattagttgt gtattcctct aatgcaccgc ttaaacaaaa
    26161 gatgaatgtc aacattgctc cttcaaagta attaccgatc aaacaggcac caatagcagc
    26221 taaagccatc aataaatcca cattcagtgt ccgatcattc cacaattctt tcaagccttc
    26281 cgatgtttgt ttatatccac cgatgataat ggcactgata taaaaaagtg gggtgatggt
    26341 aagagagaat cggtcgaaga taaaaccgaa gatcataaat aaaaggcagc cgattgttgc
    26401 tgcaaaagct tttttctgat tagtcatcgt tattagacct ccttgtcaaa acaaggatag
    26461 cataataaaa atgtaattga taataataac agctaaatga gaacgataat ggttatcatt
    26521 tggtgattaa gcttgatgtt gtttttatta tttataatga ttattattaa agaaaataaa
    26581 aaaccagaac atttctcaaa taagagaagt gttctggttt tttctacatt gcaataaacc
    26641 aataaccaat caaaatgata ccaaggataa tacgatacca gccaaaagcg gtaaagtcgt
    26701 ttttcttcaa atagcttagt aagaatttga tagctaagac ggaaaccaca aaagatacga
    26761 atgttcctac aagaagaaca acagtttctt ccattttgaa tgaattccct tcagctaaat
    26821 atttgacgat cttcaagccg cttgcgccaa acatgacagg aatccctaag aaaaatgaaa
    26881 actctgtagc gacaaaacgc gaagcaccaa tcaagataga tcctaggatc gttgcgccag
    26941 aacgggatgt tccgggaaca agtgccaaga cttggaataa cccaacaaga agagctgctt
    27001 ggtacgtaaa gtcattcaga gaagtccaac gaggtgtttt gtttttgttg cgtttttcga
    27061 caataataaa ggcaataccg taaacgatca aaacaatggc aactggtaag aacttgtgga
    27121 aatttgcttc taaccaatca tccaaaggca aaccaatgat gatggctggt atgcaagcaa
    27181 cgatcacttt aaaccaaagt gtccacgtat cttttttttc taccgttgat ttacttggag
    27241 aaaatgggtt taacttgtga aaataaagaa cgacgacagc caagatcgcc cctaattgga
    27301 taacgacatt gaacatcgac ataaattgtg aactggcatc cagtttgatg aattcatctg
    27361 ctaggatcaa atgaccagta ctactgatgg gcagccattc cgttattcct tcaataatac
    27421 cgagaatcac tgctttgata atatttgcaa aaaacataaa ttccttcctt cccaattaag
    27481 atacatctta tagtataccg ttattttttg agaaacccaa tctgtttttt aatattaaga
    27541 aaaacttgag aaataaagca gataagtaca cgaagagaaa aaagaagaca aagccctcgt
    27601 tcagactttg ccttttatga ttctctggta aaaattaaaa tatccccatt atagaaacga
    27661 gtcgcgacta tgtgttttcc cgttatcgat ataagacgta tcattgatgc cgtggataga
    27721 aaatcgaccg tttgcataag tgacctttgt tacgctgcca tttaaaagcc cagcacgaac
    27781 aggctgttta ggatcgatca gattaagcaa aaaggcgatc gtcaaaccat gagatacgac
    27841 taaaacattt ccaccaccat ttttttcgca gtgatgggcg atatcttcaa atcctgtcca
    27901 tacacggtct cgcaatgttt cataagtttc cgcccaccca gcggtatcta agttgtatac
    27961 agcattagca atttgttcaa aagaaacttc tgtggtaaac atttcatcat atgttttaaa
    28021 attcaataca cgagggatca caccccacat ttccatgtca tatccacctt caagagaccc
    28081 gaaacaccat tctctaatcc ttttttcaat aaaataagga atttcttttc ccttagaatg
    28141 ttctcctaga ataatacggg cagtttcgat tgcacgacca ctgtcactag aataagcaaa
    28201 tgaaaagtcg acatttttta acccgcgacc taaataatga atgccttctt gtccttgctt
    28261 tgtgaggggt gtatcacacc agccttgtac tcgttcaatt gtattgaaca tcgtttttcc
    28321 gtgtcgtacg atataaagtg tagtttctgt cattttattc tcctcctaag tcgttttaac
    28381 gattgaaaaa aggatttgtc cttttttcct gttcaatcgt cgttgcatcg ccatgtcctg
    28441 gatagactgc aaattcatca ggtaatacaa acagctgggt ccgaatacta tgaagtaatt
    28501 gttctaaatt ccctgtatac agatcggttc taccgatact tcctctaaac agggcgtcgc
    28561 cagaaacgac aaaatcatca aaaataaagc tgacgcttcc tatagaatgc cctggggtag
    28621 ggacgacgcg aaaagacatg tttcctaaag tataagtttt catttcaaat tcatattctg
    28681 caggcgagac aataacatca gcaatatcat catgtctacc gagtccagaa agattcaaaa
    28741 tcggatcacc tagccatttt tgctctagtg ggctgacata aactgggatt tgataatacg
    28801 cgcgtaaagg ttccactgca ccgatatgat cgtagtgagt atgggtaagc aaaatcgcta
    28861 ccggctgttg gtttgttttt ttgatttctt gtttgattcg ttccgcatct tctccagggt
    28921 caatgatcaa aagtgcttct tcgttgtaga ccaaataaca gttttcttca atcattcctg
    28981 tttttaatct ttcgatatgc atgtgcattc ctccttgata gccaaaactt ctttcatcca
    29041 ttagtataac gcattcattg ctaggaaaca aaaacaggta cttatttctc tttacttatc
    29101 tgaattatca gactatatga aaagtatttg gatattctaa agagaaggaa agtaagtttt
    29161 catagcattt taatatgtcc ttgttacatt agattcatcc aaaaatccaa attctatatc
    29221 c
//
LOCUS       DAFBSV010000026        29154 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.027, whole genome shotgun sequence.
ACCESSION   DAFBSV010000026 DAFBSV010000000
VERSION     DAFBSV010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29154
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.027"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(<1..1030)
                     /locus_tag="LLB18_001104"
     CDS             complement(<1..1030)
                     /locus_tag="LLB18_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5244118.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1112..1801)
                     /locus_tag="LLB18_001105"
     CDS             complement(1112..1801)
                     /locus_tag="LLB18_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBK5244119.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="LLB18_001106"
     CDS             complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="LLB18_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBK5244120.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2328..2831)
                     /locus_tag="LLB18_001107"
     CDS             complement(2328..2831)
                     /locus_tag="LLB18_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBK5244121.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3035..3162)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="LLB18_001108"
     CDS             complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="LLB18_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBK5244122.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="LLB18_001109"
     CDS             complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="LLB18_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBK5244123.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4799..5467
                     /gene="sdaAB"
                     /locus_tag="LLB18_001110"
     CDS             4799..5467
                     /gene="sdaAB"
                     /locus_tag="LLB18_001110"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HBK5244124.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5480..6352
                     /gene="sdaAA"
                     /locus_tag="LLB18_001111"
     CDS             5480..6352
                     /gene="sdaAA"
                     /locus_tag="LLB18_001111"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HBK5244125.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6443..7462)
                     /locus_tag="LLB18_001112"
     CDS             complement(6443..7462)
                     /locus_tag="LLB18_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBK5244126.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7635..8540)
                     /locus_tag="LLB18_001113"
     CDS             complement(7635..8540)
                     /locus_tag="LLB18_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBK5244127.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="LLB18_001114"
     CDS             complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="LLB18_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HBK5244128.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9245..9415)
                     /gene="secE"
                     /locus_tag="LLB18_001115"
     CDS             complement(9245..9415)
                     /gene="secE"
                     /locus_tag="LLB18_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBK5244129.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="LLB18_001116"
     CDS             complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="LLB18_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBK5244130.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9753..10397
                     /locus_tag="LLB18_001117"
     CDS             9753..10397
                     /locus_tag="LLB18_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBK5244131.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10453..10956)
                     /locus_tag="LLB18_001118"
     CDS             complement(10453..10956)
                     /locus_tag="LLB18_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBK5244132.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10969..11015)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11553..12518
                     /locus_tag="LLB18_001119"
     CDS             11553..12518
                     /locus_tag="LLB18_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBK5244133.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12617..13789)
                     /locus_tag="LLB18_001120"
     CDS             complement(12617..13789)
                     /locus_tag="LLB18_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5244134.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13776..14921)
                     /locus_tag="LLB18_001121"
     CDS             complement(13776..14921)
                     /locus_tag="LLB18_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5244135.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14935..15867)
                     /locus_tag="LLB18_001122"
     CDS             complement(14935..15867)
                     /locus_tag="LLB18_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5244136.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15984..17063
                     /locus_tag="LLB18_001123"
     CDS             15984..17063
                     /locus_tag="LLB18_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBK5244137.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17060..17689
                     /locus_tag="LLB18_001124"
     CDS             17060..17689
                     /locus_tag="LLB18_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5244138.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17799..18026)
                     /locus_tag="LLB18_001125"
     CDS             complement(17799..18026)
                     /locus_tag="LLB18_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBK5244139.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18129..20717)
                     /locus_tag="LLB18_001126"
     CDS             complement(18129..20717)
                     /locus_tag="LLB18_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBK5244140.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20737..21396)
                     /locus_tag="LLB18_001127"
     CDS             complement(20737..21396)
                     /locus_tag="LLB18_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBK5244141.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="LLB18_001128"
     CDS             complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="LLB18_001128"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBK5244142.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22169..23035)
                     /locus_tag="LLB18_001129"
     CDS             complement(22169..23035)
                     /locus_tag="LLB18_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBK5244143.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23144..23785
                     /locus_tag="LLB18_001130"
     CDS             23144..23785
                     /locus_tag="LLB18_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBK5244144.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="LLB18_001131"
     CDS             complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="LLB18_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBK5244145.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25226..26125)
                     /locus_tag="LLB18_001132"
     CDS             complement(25226..26125)
                     /locus_tag="LLB18_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBK5244146.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26127..26924)
                     /locus_tag="LLB18_001133"
     CDS             complement(26127..26924)
                     /locus_tag="LLB18_001133"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HBK5244147.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26902..27606)
                     /locus_tag="LLB18_001134"
     CDS             complement(26902..27606)
                     /locus_tag="LLB18_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBK5244148.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27737..28312
                     /locus_tag="LLB18_001135"
     CDS             27737..28312
                     /locus_tag="LLB18_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HBK5244149.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28430..29107
                     /locus_tag="LLB18_001136"
     CDS             28430..29107
                     /locus_tag="LLB18_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBK5244150.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8582 a         6173 c         5242 g         9157 t
ORIGIN      
        1 atacagtatt atttcggttg cttgctgctt cacctagccc ttgtactcgt gtttgattgg
       61 cgacttgacc aaattgattc ccgacgtcta ataaaataat agctaaaagc aaaatggcca
      121 aatggcttcc gccaaccaat aaagcaataa agcttattgt ttgcataaca agtcccatat
      181 acacgatttt tctttcagaa taagaatctg ccagtcgtcc cacgataggt gcagcaactg
      241 ctccagacaa accaaaaatc gctaatatcc ctgcttcgaa tgttccccaa ttgtaggcgg
      301 gactgctgat ataaaaaatc aacgtagacc aaaagatcga aaatgttcca aacatgaaaa
      361 atccactgac tgccgcttct cttaatagac gttgagaagc aactaaatgc ggcaaacttt
      421 taagtgaatc aaggtatgaa acagctgtac tactttgctg gacagaacgc ggcattttcc
      481 agtaaagcag aagtgtaaga attccgactg cacataaagc aaataaatag atcatccgcc
      541 aagaaaaaag actggcaaca ataccagata ccgtccgaga aagcaaaatc cccacgagta
      601 aaccgctaag caatgtaccc atgaccttcc ctcttgcttt tggtcccgct agtaccgcac
      661 cgtaaggaat gatgatttgc ggcacgatcg aaagtaatcc tattaaaaaa gaagcgcatg
      721 caaataacgt aaacgaaggc gcaaaaaaag cggccaacag agagacggca gataacgcta
      781 ccattcgaat gatcaatttt ggacgatcca ccacgtcccc taaaggaact aaaaacagta
      841 accctaacgc atagcctaat tgggtcaaca tcgtcaatat cccgactgca cttgtgctaa
      901 cagataaact agctgctact tttgttccaa tcggctggat gtaatacata ttggcaacaa
      961 caacgccaca agtgattgat aatagtaaaa taagcgaagt tgttaaaggt gttttttcat
     1021 tactcttcat tgatttcccc catttcctat cttagtttac aacttatgga aaagattgga
     1081 aatagaaaaa tacaactatt cgccacactt attatttgtg cttttgtttt ccttgttttt
     1141 tcttgcgatc tttataaatg aagacaacta accctactag cacagtaaca cttgcaacca
     1201 acgtgactgc agttttgtta tatccgtgaa acagagcttc tccaccacac gcatacaaca
     1261 cagacgaagg gatgactcca atcacgatcg acaatatgat ttgctgtaga ggcaatttca
     1321 tcgcatctgc agcaaaattg accatagaag atggaataac cggtatcata tagcctaaca
     1381 ttacacctat ttttggatgt ttcatttgtc ggattgcttg cacccaatga ttcgtttcgg
     1441 ttttcttatc taaaaatttt aagcgatgca taaggaaaat tgcagtgatg ttaccaagag
     1501 cattacccaa aatgttgatg atcgcacctg tcagtggtcc aaagctcaaa ccagcaatga
     1561 ctccaactac tgaagtagga atacctggaa cagcacacat caccgctgtc aatacgatca
     1621 agagtatcga tgcaaaagtc ccatgcgaac gaatatgtgc gagtagctct gccttactcg
     1681 ctctcggatt taaaaataat tggatgtctg tctgatattc taaatacaac cgatagccca
     1741 ctaccagtat cagaatgatt cccaacgaga tcaacatcaa tcggattatt ttctttttca
     1801 tatttcctcc tgaaaaaaat ctatattcat taaataatag tttaacataa aaacaaaaaa
     1861 gcaccgaaat ccaacatagg atctcagtgc ttttaaatag taaaaattat ttaacagtta
     1921 cagatgcgcc aacttcttca agtttagctt tcaattcttc agcttcttct ttagatacgc
     1981 cttctttaac tggtgcagga gcgccatcaa ctacagcttt agcttctttc aagcctaaac
     2041 cagttgcttc acgaactgct ttgataactt taactttttg gtctccagct gcagttaatt
     2101 ctacagtgaa ttctgtttgt tcttcagcag cagcagcgcc accagcagca gctacagcta
     2161 caggagcagc agcagatacg ccaaattctt cttcaatagc tttaactagg tcgttaagtt
     2221 ctaggatagt tgcttctttt aactcagcaa cgatgttttc aatgttcaat gccattataa
     2281 tttcctccgt ttaattgttc ttttttattt aatgctttat gcggcaatta agctgcatct
     2341 ccatcttctt tgtctgccac tgctttgaca gcgtaagcca cgttgcggac tggcgcttgt
     2401 agtacagata gcaacataga tagaagtcct tcgcgatttg gcaattttgc caatgctgtg
     2461 atttcttcca atgaagagac tttaccttcg atgataccgc ctttgatttc taatgctttt
     2521 gcttctttag caaattcgtc catgattttc gctggtgcga ctacatcttc gttactgaat
     2581 gcaacagctg taggtccagt gaatacttcg tccatgcctt caaggccagc ttttttagct
     2641 gcacgtgaaa gaatagaatt tttgataact ttcatttcta cgttagcatc acgaagttgt
     2701 ttacgtaaac gtgttacttc atcaactgtt aatccgcggt agtcaacgac tactactgat
     2761 gcagctgctg taaatttttc gcttacttca tcaacgattg ctgctttttt tgcgataatt
     2821 gcttcactca tttttgagtt tcacctcctg aattttgatg gaagagtttt ttgcactgaa
     2881 aaggcaagtc acttttatag ttactttgct caaccagtat tattcatcac ctattcactt
     2941 cgttcatagt gattctactc gctttgctcg aaaggaaact cctttcgctt tgctcaacca
     3001 gtattgttca tcatctcttc acttcgttca tagtgattca caataaaaaa ctctatgcca
     3061 ccgcagacat agagggacta ttgaatatat tcaataaacg tcctcggtag gaaattaagg
     3121 cttgatgcca cctactgtct tcggtacaag ttaattatta acctcaacta gcttagcatg
     3181 ctaaactagt tgagtcaaga attatttttc agttggatca atcaacattc taatatttaa
     3241 ttagaaagaa gcttggtcaa catggatacc aggtccaaat gttgttgtga tcgttacatt
     3301 tttcatgtat tgacctttag ctgctgatgg tttagctttt agcaatacat catggattgc
     3361 tgcaaagttt tcaactaatt tttcatcgtc aaatgaaact tttccgattg gtacatggat
     3421 atttccagct ttgtccacac ggtaagttac tttaccagct ttcacttcgt ttactgcttt
     3481 tgttacgtcc attgtaactg taccagtttt agggtttggc attaagcctt ttggtcctaa
     3541 tactcgtcct agacgaccta cagtagccat catatcaggt gttgcaacaa ctacatcaaa
     3601 gtcaaaccat ccgttttgga ttttttgaac catgtcgtcg tcacctacga aatctgcacc
     3661 agctgcttca gcttcttttg ctttgtctcc tttagcaaaa actaaaacag tttgtgtttt
     3721 accagttccg tttggtaata caacagcacc acggatttgt tggtctgctt ttttagggtc
     3781 tacgttcaaa cggtatgcaa cttcaactgt tgcatcaaat tttgcaatgt ttgtttcttt
     3841 tgctaaagct actgcttcgg caacaggata aactttactt gaatcaactt tttttaatgc
     3901 atcttgcatt tttttgctct ttttagccat tttggttcct ccttgattgt ggttataacg
     3961 gttgtacctc ccacgtgttc tatatctttc aatatagagc caactgagaa gctgctgtct
     4021 tagggtgtat agattattct acagtgatcc ccatgcttcg tgcagttcct tcaaccatgc
     4081 gcattgctgc ttcaacgtta gctgcgttta ggtcttccat ttttaattca gcgatttctc
     4141 ttacttgatc gctagaaact ttcgcaactt tatttttgtt tggttcgcct gaaccttttt
     4201 cgattttagc tgcttttttc aatagaacag cagctggcgg tgtttttgta acgaatgtga
     4261 atgaacggtc ttcgtataca gaaataacaa ccggaatgat caaacctgct tgatcagctg
     4321 tacgagcgtt gaattctttt gtgaatccca tgatattgat acccgcttga cctagtgcag
     4381 gacctactgg tggagctgga gttgctttac ctgcaggaat ttgcaattta acgatttttt
     4441 ctactttctt tgccacgaga catacctcct taagtccgtg atgtggttaa ttggagatgc
     4501 atatttctcc tcccacgttt tatctgatct gaaaaaatcc agacaaataa tgtgcaaaac
     4561 aatgcacact ggtacagtat agcaaattta tttgtttttt caagattttt ttctgctatt
     4621 tttacatttt gcttgaataa acgctaaatt tattctaaaa aaacaacaat ttttcgttct
     4681 catttcttct tttatgttac acttgcgcta gcatggttca acagatgaaa gcaaacaata
     4741 acacggtttt ttagaccctt gtacaaagat tcctacataa caaaatgagg tggagaaaat
     4801 gaaagattta aggtatagaa gtgtctttga tattattgga cctgtgatga ttggtccaag
     4861 tagctctcac actgccggag ctgctagaat cgggaaaatc atacgtagta tatttggcga
     4921 acagcctgat tctgtagata tttatctata tgaatcattt gcaaaaacct atcgggggca
     4981 cggaacagat attgcattag ttggcggcct gttagggatg gaacccgatg atgaacgttt
     5041 agctgattct ttgaaattgg catatgaagc cggtatggaa gtcttgtttg ttcctaagag
     5101 tgaaaaagcc gaacatccaa actctgtaaa gatgcttcta aaaaaaggaa cacgaaagct
     5161 ttcagtcact ggcatttcga tcggcggtgg caatatccag atttctgaat tgaatggatt
     5221 caaaatttct ttaagcatgg gtactcctac cttgatcgtt gtccaccaag atgttccagg
     5281 tatgattgct aaagtgacta gtatactttc tgagaccaat acgaatatcg gcactatgac
     5341 agtgacacgg gaatcaaaag gtgaaaatgc cattatgata attgaagtag atgatcctca
     5401 agtagaagaa acggtaaaaa gactcaaaca gctgccaaat atcgacagcg taaattattt
     5461 cgattaagga gctaaaaaaa tgtttttatc gattgaagaa ttagtagatc aagcaaaagc
     5521 ttatccaagt gtagcagaat tgatgattgc agttgaaatg gaaatgagtg gccgttcccg
     5581 tagtcacatc atcgagatca tggaaaaaaa cctctcagta atggaacaat caatcaacga
     5641 gggaaaagaa ggtgttacct ccgtcacagg aattaccggt ggtgatgcaa aaaaattaga
     5701 tgattattta aatgaggcag actttttaag tggagaaaca atcttaaaag ctgtacgcaa
     5761 tgctgtagct gttaatgaag tcaatgcaaa aatggggttg atttgtgcta caccgactgc
     5821 cggaagcgcg ggtgttgttc ctggtgtgct gatggctgtc cgagatcggc ttgatttgac
     5881 acatgaacag caattggaat tcttatttac cgctggcgct ttcgggttag tcatcgcaaa
     5941 caacgcttct atcagtggtg cagaaggggg atgtcaagca gaagttggtt ctgcaagtgc
     6001 aatggcagca gcagctttgg tttgtgcaaa aaatgggact cctcatcaag cagcacaagc
     6061 agtagccatt acattgaaaa atatgatggg actgatttgc gatcccgttg caggcttagt
     6121 tgaagtcccg tgtgtcaaac gtaatgcttt aggctcttct caagctttta tctctgctga
     6181 tatggcatta gcgggtatcg aaagtgtcat tccgccggat gaagtcgttg ctgcaatgta
     6241 ccaagtcgga cgtcaaatgc cgtcgatttt caaagaaaca gcagaaggtg gcttagctgt
     6301 tacgccaact gctaaacgac ttgcggaaga gattttaaat aagagggcgt gataaagctc
     6361 cttaatttcg agtattaaga gattagttat cttcataaca aaaaacgaag agaggactaa
     6421 ttgcccttct cttcgttttt tattaatcca tcaatttcgt attttttact tcatcgatcg
     6481 tttttgttcc tgcaagttgc atcgtgatcg acaattcttt gttcaggtgt tcaaaaacag
     6541 atgttactcc ttctgcccca cctagattca acccataaat cactggtcgg ccaatcgcaa
     6601 ctaagtcagc accacttgcc agagctttga agacatgctc tcctcgacgg acaccagagt
     6661 cgaaaatcac tggtacacgt ttgttgacta cttcggcaat ttttggcaat acttcaaagg
     6721 acgcaggacc tccatctaat tgacgtccac catgattgga tacccagata ccatctgccc
     6781 ctgcagagat agcgattact gcatcttctg gcgattgtat tccttttacg ataactggaa
     6841 gatgggtgat ttctttgatt gttttgatgt catctggtgt caagccttgt tttgcagctg
     6901 cataaatttc tgcgattcct tttccttcgc cattaccact tgcactttgt tcgctatacg
     6961 cagctaagtt aggcattggt aatggaaatt ggaattgatt gatgacgtct tcttcacggt
     7021 aaccaccgag cgttgaatct gccgttaaaa tgatagcttt agcccctgct tctactgctt
     7081 tgttcaaaat gaactcattg aatctgtcgt ctttactcat atataattgg aaaaactgcg
     7141 gtgcgcctgg cgctgcatcg gctgcgtctt tgattgtcgt atttgcataa gtgctgatgg
     7201 aaaagattga tccagcagca gctactcctt tagctgtatc agcttcccct ttttcatgtg
     7261 ccaatccttg ggccgctgat ggcgcttgga taatcggtgt atctaattca attccgaaaa
     7321 cagatgtatg caaatcggct gagtcgattc cgcgtaatat ccgtggcatg attttctttg
     7381 tattaaaaga agtcgtattt tctttcatcg tccactcatc ttcagaacca ccgcgaatat
     7441 agccaaaagc tcctgcttcc atgcgctctt ttacacgacc ttctagttag gcaatgttta
     7501 caatatcgat tggatgttct tcattacttg tatgataagt catagtagat ccttctttca
     7561 tcttcttgat tacatataaa tcatactaaa cttacaaaaa gtaagcaaac atttactctc
     7621 agatactttt atcgctattc tttccaaata aatcgactta caagctgatc tacttcttgg
     7681 ttttcatgaa gcatactatg agaggcattt tcacctgtca ctactttttc ctctatttca
     7741 tttccgcgtt gcttcaacaa cgcatagacc gctaatgcac tgtttaacgg tactgttcca
     7801 tcactcaagt ctgtttcatc tagttgacca gcaatcaaga aaaatcgagt ggttatagga
     7861 atattaccga tcatttgctg gtaatcttga tagcggttag aaacgacagc aggccccttt
     7921 gctaactcat ctgtcagaga ctgcgcacta tcatcgacaa aatcattaaa aggcgcgcca
     7981 attgctgtta atgtctgaac ttgtggcaat gacgtatcct gtccatacgt tcctaaatag
     8041 cgtagtgcac taactcctcc catggaatgc cccactatgt tgactttatc tatgccgtag
     8101 ttttctttca gatacaaaag acaagttttg atccattctg cttgattcca ctcgttattt
     8161 ttattatctt caaacaatac ttggaccatc ggattgtctg cttttccaga caaatctcct
     8221 gttgcttgta tttgtccatc tgttcctact gttaaaacca attcttttac tgcttgctga
     8281 tttttttcca aacgccgcaa catcccttta aaggaatttt ctgtcccgct gtagccgtgg
     8341 aaaaaaagtg ttggaatagt ggttttttct atcactttac tggattctgc cgttttttct
     8401 ttatcagaaa cttcagtagt atttatcttc gtcgtctggc aaccacttaa cgcaaacaaa
     8461 ctgataagga ctaaagctgc tgcagttgca cgtttgcata aatttttgat tggttctgtc
     8521 atacacctct tcctttccat atagaaaaaa gaaagacttg aaaggccaat catatgatcg
     8581 acatttcaag tctctttatt aatcgatttt atctacttga tcgaaatcaa gttctgtact
     8641 ggtttcacgt ccaaacatat cgatgttgac tttcaatttt tctttttctc cgtcaacttc
     8701 tgttacttgt ccttctaatc cagcaaatgc gccttcgatg attttcacga cttcgccaac
     8761 ttctacttct agatcatttt gtcgcaggct cataccgata gaacgcaaga tatgattgac
     8821 ttcttctgga agtaatggtg ctggtttgct tccggctccg tgtgaaccaa cgaatcctgt
     8881 cacaccaggt gtgttgcgga caacatacca tgaagcgtct gtcatgatca tttcaacaag
     8941 tacgtatcct gggaatgttt tatgaacgat ttctttttct ttcccatttt tgacttcagt
     9001 ttctttttct tcaggaacaa cgacacggaa aataaagtcg gccattttca tactttgcgc
     9061 acgagattcg atatttgctt ttactttgtt ttcatatcct gaatatgtat gcaagacata
     9121 ccagtttttt tcaaaagatt ccattgaagg ctcctcattt cattgtaaaa taaaaaaacc
     9181 tcagtacacc cgaagttttt ctttcgcttc attatagcac taaaagtacg ttgtggctag
     9241 cgagttattt taaaatccag ccaaataagc tttggatggc tgtatccatt acgtaaaaca
     9301 tcaatccgaa aataatagaa gtttcgatga ctactaacgt atctttacgg agttgttttc
     9361 tgcttggcca agttacttgt ttgatttcat cttttacgct ttttagaaat ttcatgagac
     9421 aacctccctt gctactgttt atttcgtttc tttatgtaat gtatattgat tacaatattt
     9481 acaaaactta ttgatttcca aacgttcgcc gctttttcct tcactgactg attttgtgta
     9541 gttgcgagac ccacaaacgg aacaagcgag tgctgctttt ttctttgcca tttacttctg
     9601 cccccttgct gagaatcaga cttatacttc ataacagtat cacgtaactt tttacttgtc
     9661 aatttgtgaa ataaactatc tattgttttg gataaaatta tgatatgatt aatttgaaat
     9721 taagctaaaa tgagacaatt ggaggtatag cgatgctatt aaaaacactt gtatataaga
     9781 aaaaagatct gacaaccgtt acagagacta gtacattaga agaagcatta aaaattttag
     9841 aaacttccgg ataccgttgt gtgccgatct tagattcttc aggtaatatt ttccgtggaa
     9901 acatttacaa aatgcatatc tatcgtcata aagcaaatgg cggtgatatg acgcttcctg
     9961 tcactcatct tttgaaaaac gctacaaagt tcatttacct ggatacttct ttcttcaaag
    10021 tattctttac gatcaaagag cttccttata ttgctgtcct tgacagtgaa aatcattttt
    10081 atggtatttt gacacatagt acgttgctta atatgctctc tcaatcttgg agcgtagaac
    10141 aaggaagcta tgtactgaca attgcttcca caggaaagca aggagatttg gctgctattg
    10201 caaaaatcat ttcaaaacac agcagcattg ccagctgtat tactcttgat atcgaaaaag
    10261 acgaatacat tcgacgtaca ttgatcacgc taccggctaa cactgaagcg aaagtatgtg
    10321 aaacgatcgt caaccactta gagaaaaaga attataaagt ggtagaaatt gaaaatttgc
    10381 aaaaccaaga agcataatca aaaagcgaaa aaagaaaaca gctaatctgc tttctttttt
    10441 cgctttttat aattagacac gcttttcaaa atcaagcgcg cgatctaaat aatacatcaa
    10501 tggtgctgaa acagccatga cgataaactc acttaatgca agcgtgccat aggttgtcca
    10561 aaatgcttgg ccacctgttg gaactaacat ataagcaatc agtcccatgc tgatggtaaa
    10621 gaagatcgtg ttcaatacta aacgcatctt tacatttttc actttgtttt gcaataaagc
    10681 tgtcaggcct aaagaaagca atgtttggcc gccaccaaaa accacatcca tgataccaaa
    10741 accaaagaag gcattataga cgatgacccc gcctaaaact ccccaaagca atttacggtt
    10801 aaagacaact aaatgattca aactttctga aatacgaaac tggatcggcc ctgaggatac
    10861 aggcgcaact aaaatagtta acgctagata aagagccatg atgatgccat ttacaacgat
    10921 tacggataac cgttgtctgc ttttcgtttt ttgcattttc tctcctcttt tctcctagtt
    10981 tttttaacgc gggatggttg atgaaccgcg gttatgtgaa acaaacaata attataacag
    11041 acttttcatt tatttcaatc cgtcttatct gcttttaaaa aagcaaaagc ttaaacaatg
    11101 taaacgtttg ctaaaaatcg tgggatatgg tataaagtaa gtgtaagggg tcataagaat
    11161 tcccagtaaa gcagacgaag taggatctgc aagaacagaa ttgttgtgaa acttaaataa
    11221 ataaaaaagg atgtgggaat ttgagcaacc tcttactaga gaacggtcta gcaagcagct
    11281 gaagatctaa gtggacatgc cgaaccttgg aacttctcct tacgtaagta atggatcatg
    11341 cgcttgctag gcttttttgt gtttttcggt cttcggacct ttttcatttt cctagacttc
    11401 tgctataata accaagaatt aattttgtaa cagatttttt tgaaaaaaca agtttctttc
    11461 attcaaaaaa tagaaaaagc ttgctaatta ttggttaacc agcaaacagg agtattaaaa
    11521 tatcttgttt tattgaatag caggaggaaa tcatgaaatt ccattatcat atattgatca
    11581 atccatcggc aggcagcgga aatggctata aagtagcaga aagaatttta ccggtattaa
    11641 aaaataagca tattgactat acacttcatt atagtgaata caaaggacac gatgctgaga
    11701 ttgctgaaac tttggcaaaa gaaacattga ttccttggat agaagaagaa cagaaaacaa
    11761 tcgatacttt cccccttttg atcatcgtag gaggtgacgg caccttacat caggtacttg
    11821 atactttcta tcagatggaa gtagaattcc cagttgctta tattccagca ggttctggaa
    11881 atgattttgc tcgaggggca ggccttccaa aaaatcccaa aaaaggactt cagctgattt
    11941 tagcagctca atcaccagaa aaagtccaca taatggctta tgaagaaaaa ataagtgaaa
    12001 aaaaaggaat agctgttaat aatttcggta taggattaga tgcagctatc gtccatgcga
    12061 caaatcattc ttccacaaaa aagcgattga acaaatacaa cttaggatca ttttcgtatt
    12121 tattctctat tctccgtgct ttattcactc aaaaaggatt tccaattctg gtagatgcag
    12181 gaggaaaaca attaagtttt tcaaacgcat ttttatgtac agcaacgaag catccttttt
    12241 ttggcggagg aatcgcgatt gttccaactg ctgatgcgtc taaaccagtc attgattttg
    12301 tcgtggtcga acgaatcaat ttctttaaaa tcttgtggct cattctttta cttatacaga
    12361 aaaaacaatt gaaatcgaaa tatttccatc actacacaac aaacagatta cgtatcgttt
    12421 caacaacacc gcaacatggt caagaagatg gagaagaaat ggaaaaacga ccttttgata
    12481 tcacaataac cacaactaaa cagttgtttt ggtgttaata aaagaggttt tgtcagaagc
    12541 tacatctgga acaccgttta ttcggaaaaa aggactgtga cacgactttt gtcacagtcc
    12601 tttttttact atgcagttaa ttctttgccc aattgggttg ccatcgatag tttctttctt
    12661 tacccaaaat aaattggatc attgaaaaca ccgcagcaaa agcaactaag acacaaccat
    12721 tgaaccaaaa agattctgca aatgtttgat tgtaactgag tgtttcactg atcaagttat
    12781 tattttgaac aaaccaatat gttggtgtga atgccgctat tttgctaacc atttctggca
    12841 agtattctgc tggtacaaac accccaccga taaagcaact gcctgtgata aaaatatctt
    12901 tgatcccacc gctggtttct gagtttttta ccaatgaagt gatacaagcc gaaaagctaa
    12961 tgatcggcaa taaaaacaag aaagtattta aaatatgata ccataccgtt atatcccacg
    13021 aggtgtggat cactaacaga accattagaa gtaagaagcc actgaacaac agcagcgagt
    13081 aactaatcaa actaaaggtt actttgcgat tcaagtttcg tttggtaatg ggcgcactct
    13141 ggtttcgttt actgatctct ttgcgattaa acgctagatt gatgacgctg aaaccgctaa
    13201 aaatggatag aaacaaccca taagacaaga aattaaaggt tgtgcccgtc aacagctttt
    13261 tcatccgctg actatatccc gcacttagct caacttctcc agtaaccgag agtgccattt
    13321 gtgtctgttc catagctgca tcgattgttt tatcttcttc ttgaaacaga atcagtgttt
    13381 gcaaaaaggt gttcacttgc tgtgtaacaa ctgttttaga aaaggcatct gggcgactct
    13441 gtatcttgat cgtcgccatc tttcctactt cgacttgttc ggtaaagtct gcaggcagat
    13501 gtaagataat gtttacacga ttaaaataaa gagcatcatc gatttctttt tgtgaggttc
    13561 catccaatgt aacgactgtt tccttgtcat tcaaatattt acgaaggcca tcgactacag
    13621 gcgactcttc ttcactaatc aaggcgattt tcgcatcttg cagagaggta ttttcaacat
    13681 caatattttg cgcaaaaaag aatgtggcaa caacagtgat aattacacct atcagtaaat
    13741 tcgatttatt tgctttaagc aatgtccaaa tcgttttata aagcgtcata acgcacccct
    13801 ctttccatcc aagcatttcc taacgcaaaa aggaaaataa atccgatcaa ccatagaaga
    13861 ttggtataaa aactagccaa atcagtgtag aaataaagtt tatacaaact ttcgctgatc
    13921 aagttgacga gatttaattg accaacaatc ggaatatgaa gatcaatcca atacttcact
    13981 tgttccgacc ccatcatacc agcaaaaaag ctcatcgcaa tcgtcactga aatcaagatg
    14041 ctatcctttt gcaccagatt catttttggt atcaaattac caaccaatgt acctaacaaa
    14101 atcgcacaca acgaccccag agcggtaaca atcatcaacc attgccaacg ttcaccaaag
    14161 tctacttgat agataaaacg aaagacagct aacataatat aaatctctgt caaaacaatc
    14221 gtaaagcttg ctgccaaatt agcgattgaa actaacgatt gctttctagg aatcaaggac
    14281 aagcgaatac catttgacga ttgatttgct tgctgatcct gtacattgcg gaccccccac
    14341 atcgtcccgt agagaatcgc cattccaatc agagtgaaga aataaaaact tttgaaactc
    14401 atattacgac ctgcatgaac ttcttgaaaa gatacttctt gttcaaaaac agtcatgatg
    14461 ggcgcgagat caacgttctc cacttctgcc actttactcg aaattatacc aatacgctgt
    14521 aaaaattgat ccatgacgtt tttcatcaac gtctgactca ttcctgcttg acccacatgg
    14581 agcgaaacag atgaaccatc aatgagataa aaaccagcca aatcatctgc atttagcttt
    14641 tcattcgctt ctacttccga tagttcctgt acttcaaata atggtttatc attgacttcg
    14701 acttgttcta agactgtggt aaaattttcc gaaagcgctg tttgatccgc tttgattaca
    14761 attccagtat taatcgtttc aagattgcca ccttgatcaa tctcgccaaa ggccgccata
    14821 aacatcaatc ctaaaagaat tggaaaggcc aatgtccaaa acaacatgga tttatttcgc
    14881 agcagtattt ttgtgcgata tttataaaaa tgccaaaaca ttatttcccc tcctctagtc
    14941 tctcaaatcc ttgccagtaa tctctaaaaa gacatcattc aaggacgctt ctttggttgc
    15001 tatttttccg taactgatct tttcttcttg taagattgta agaatcggca acaatactgt
    15061 atttagttca gtagttgtta cttggagctg acctttttta taagcgattc catcagaagc
    15121 tattgttcgc tgaatcgctg acaacacatt ttctgggagt aatgggatgt cgatcgtcaa
    15181 acgatccgcc gtccgtacca tatcttttag agattctttg gttcctttag caatcacctg
    15241 tccttgatcc atgatcacga tctggtcgca aagaatttct acttcttcca tgtaatgtgt
    15301 tgtatagaca atggttgctc cttgtcgatt cagctccttg atactttcta aaattttatt
    15361 ccgactttgg gggtctacag ctactgtcgg ctcatctaaa aaaattaacc gcggcttgtg
    15421 ggcaatccca catgcgatgt tcaaccgacg tttcaagcca ccactaagtt ctcctggacg
    15481 aaacgaaaca tatttttcta atcccactaa ttgaatcacc tcttcaatca aggctttcct
    15541 tttctctttt tcggaaacat ataaaccgca aaaataatcg atattttctt gcacacttag
    15601 ttcgtcaaag accgcaacgt cttgaggaac gaccccaatc attgccttga cagcataatt
    15661 ttcaggagtc attgttgtcc cgaacaattt aatggttcct ttgtcataat ttaacaaaga
    15721 aagcatacag ttgatggcag tcgatttccc actgccgttt ggacctaaca gacctaagac
    15781 ttctccttct tgtacttgca gatcaaaatg attcaatgct acaaaatctc catagcgttt
    15841 gactaattta tcaatttcga taatcatcat gaaaaactcc ttccaaattt cttgttgatc
    15901 tgactataat aaagtgcaag aaaagaaact agtgacgatt ggctaaacca cacatgacat
    15961 ttgtcacaat gaaggagtct gctatgcata aatctcggct actcaacgaa actagctttc
    16021 tactggttat ctcattgctt ttgctggtaa gtcaaggatt cgttgctatg caagttatct
    16081 atttattgat cgccgtttta ttcactggtg tcagttattt actgcctaca aagccaaatt
    16141 ggattttcca agttattcta tttcttttat gtgccttttt acctgatctt gtcctgtttc
    16201 tgccagcgac gatgcgagtg atcgcccctg aagaaagcca ccttgattac ttgtttttgt
    16261 taggtttttt gttgatttcg acggttggta atcatccccc catcaaggtc gcctttgtcg
    16321 taattttgct gtttttttcc ttttacttac gaaaaaaaga tcaacgaacg accgatcttg
    16381 agaaaaagta cattgtctcc aaagatactc attgggaaaa acaacaagag ttatcggaac
    16441 aaaataaagc attggccctg tcacaagaaa cacaattagc cttgcaaatt gtggaagaac
    16501 ggaaccgaat tgcccgagac atccatgaca atgtcggtca tctgctgtca agtgcgattt
    16561 tacaaattgg tgcgcttgaa atgatcaatc aagaaccaaa actaaaagaa ccattagaaa
    16621 atttaagtgc caccgttcac actgggatgg atcggattcg tcaaagtgtc catgacctcc
    16681 atgagacatc gatctctttt caacactcct tagagtttct gatcgctgat tttccttctt
    16741 ctgttacgat tgaaggaaac ttgtttgaag gattgaatga aacgcagcaa aactgcttct
    16801 taatggtcat caaagaagcc ttaaccaaca gtatcaaaca tagtcatgcc aaaaccgttg
    16861 ttttacattt tcgaacgttg ccggcctttt atcgcttgca aatcacgaat gatggcacca
    16921 gcccacaaaa aaattctgct cccggtattg gtttgaaaac gatgcgtcaa cgtgttcaag
    16981 aacaaaaggg acaagtccat attttccaag aaaaccagca atttcagtta acgatcattt
    17041 taccaaggga gggacaccaa tgataacagt agtcattatt gatgatgatc catttgtgac
    17101 gaaatcgtta caaaccattt tagaaagcac gaaagagatc cgtgtgttag gcattggtca
    17161 ttgtgccaag gatgcgctag tcttatacga aacccatcgt cccgatgttt tgctgacgga
    17221 catccgcatg cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc
    17281 caaagccatc cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt
    17341 ttccatcggt gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt
    17401 caaatccgct tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca
    17461 aatgatgaag aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga
    17521 gcttgcaatc atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt
    17581 gtacttgagt gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt
    17641 acgggatcgc acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa
    17701 cacaaaaaaa cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt
    17761 caattgtccc gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca
    17821 ggattcgttg gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt
    17881 tctagttttg attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat
    17941 tctttttcca tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct
    18001 aatttatctt cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca
    18061 tatcacactg aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat
    18121 ctttaaaatc aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca
    18181 atcatcggat ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa
    18241 acagcaggtt ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt
    18301 tccactgttt ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt
    18361 agcttttctt ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt
    18421 ccgaccaaag aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca
    18481 ttatccatga tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa
    18541 gtgacatagg cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc
    18601 gtgtagagca aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc
    18661 atcttgaatt cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta
    18721 ttccattcgt ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc
    18781 actttatctt cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg
    18841 aatacattca attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg
    18901 gtgtcgttcc aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc
    18961 attttattta acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata
    19021 tcttgtgcac ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca
    19081 atttgataag catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt
    19141 ggcagacgtc cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc
    19201 cgataaatct gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt
    19261 acttgaccag gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata
    19321 ttcgtcggaa tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca
    19381 tcaacaatca aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt
    19441 ccattcagcc ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt
    19501 cgtttagctg ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat
    19561 tttgaaggat ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc
    19621 acagtagttt tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct
    19681 tcagcgatag cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc
    19741 cgaatattct tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg
    19801 cgctggatcg aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta
    19861 gtctcttctt gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga
    19921 tcaggctgga tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat
    19981 gtctccgccg gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag
    20041 atagctgctc gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta
    20101 tctgcacgtt tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg
    20161 atgatatcca aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg
    20221 aacccgtaac gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc
    20281 tcagcaagca tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga
    20341 tcagcaatga ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt
    20401 ttcttcccga ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt
    20461 gttggctttt cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc
    20521 actaattctc cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg
    20581 actacaatct ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact
    20641 ttgtaaaaat tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc
    20701 atttcttctg gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt
    20761 ttcagttcct aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca
    20821 aggctcttca gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa
    20881 ctcacttagc tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc
    20941 tacgaataaa agtgggccat ctttatgtcg ggcaaccgca tctgctacaa cagtttcgat
    21001 acgtgtgatt gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa
    21061 atgattacgc aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg
    21121 accttctaaa gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg
    21181 acgagcaagc tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga
    21241 ataaattgct ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta
    21301 actttgtggc aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca
    21361 ttgtgtcttc ccatgtcggg taaaatatag ttccatacgc agcaaactcc tgtctttctt
    21421 ttattttact ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa
    21481 ttctaaatta gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt
    21541 cgataaattc aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc
    21601 gttttcacgc ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg
    21661 ctcttctcca tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa
    21721 atgtagttta cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat
    21781 atttacatca ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa
    21841 acctagtggc tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt
    21901 tccagtgttt gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc
    21961 tctcatattt atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt
    22021 atcaactcgg tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt
    22081 tatcagaaca ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc
    22141 ctcaactttt ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag
    22201 ttccttttaa taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg
    22261 ctttgattcg ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat
    22321 tttcctctgg tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt
    22381 cagcaaactt ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat
    22441 aaaaagcctg acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc
    22501 catcttctga gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa
    22561 ccgcgttgaa tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg
    22621 cttcggcaga ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag
    22681 cattttgaat ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa
    22741 catctaatag cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat
    22801 acatgccaga ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt
    22861 taaccgcatg ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat
    22921 ttttgcatat caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga
    22981 acagctgatg attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc
    23041 cccctcattt ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg
    23101 atacaatgcc tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg
    23161 cgctgaaaac tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt
    23221 gtgtgacaac ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt
    23281 aagttatgct ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga
    23341 cttcgtctat aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa
    23401 attagggacg gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga
    23461 ggccttagaa ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt
    23521 tgacagtatt cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt
    23581 tgaccgtatc ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg
    23641 gcttaaagaa ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt
    23701 cactgcagag aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac
    23761 caaaatcgtg gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa
    23821 tgcttattgc aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata
    23881 ttgaaataaa tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct
    23941 actgctggat caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc
    24001 gccactgtga ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt
    24061 ttccaaaaac ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg
    24121 gtcaagactt cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca
    24181 agtcgacgaa cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc
    24241 agcgaaatga agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt
    24301 aaagaagcgg tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac
    24361 gctgccttta ctggattttc attaatttct tccacattga ccccggcaag tcctgaataa
    24421 tcgctagcag cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac
    24481 aaatgatcat cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt
    24541 gccacatctt cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca
    24601 gaaatcattg cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc
    24661 tgaccttctt gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc
    24721 ttcagcacgt acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt
    24781 gtcatgatcg cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca
    24841 tcgtctgccg acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc
    24901 aagtcaacag cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc
    24961 atttcatcta ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc
    25021 gctaattctt taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat
    25081 tggtagaatt gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga
    25141 atattatttt cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt
    25201 tcatccaaac caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt
    25261 ctgcggctaa aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca
    25321 gatcataaca atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat
    25381 catcaccgag cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc
    25441 ctgtatgcag ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact
    25501 cagtctgtgc cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc
    25561 gggcgatcgg caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta
    25621 aggcctgata ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg
    25681 caaatccatg ctttgcaaaa agcatcaagc cagatgtatc ccgatctagt cgcgtcacca
    25741 catggattac ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca
    25801 ttgtcccatt tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta
    25861 ccagaacgtg ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt
    25921 catgttctcc ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca
    25981 agacattttc tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta
    26041 acagaccctt tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt
    26101 tctcataatc ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga
    26161 tgccaaaaat gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa
    26221 taaattgagc ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct
    26281 tctgtatttt ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc
    26341 aaagtacgaa acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata
    26401 ctaggatgga tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta
    26461 gaaatcgtca atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg
    26521 gctaccatcg tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg
    26581 tccggtgttt catccaaata actgatccga acatccagca agggataact aacactttgt
    26641 tcccggttcg ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg
    26701 taaaacccta aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg
    26761 tagtgatgga acgccgacaa taatgtgccg tctccgccga ctgagatgac caattctggc
    26821 tcatgatcat ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact
    26881 tctatagtct ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct
    26941 ttcgctttct ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg
    27001 ggagaataac cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa
    27061 ctgataggca gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc
    27121 ttgatattta taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg
    27181 aatctggatt tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat
    27241 caccagatga taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg
    27301 gagaactttc atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac
    27361 aaactgacac atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat
    27421 tggaatatgc cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt
    27481 gacaaattca atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag
    27541 tttcactttc aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg
    27601 ttccatagct gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa
    27661 gttttttcgt actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca
    27721 aaaaggagtc gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa
    27781 gcaagagtac gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca
    27841 gactaatatt tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg
    27901 gatccgtttc gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg
    27961 tctcgaaaca acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg
    28021 tctgcctcgt tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc
    28081 attaatccaa accggaaagc ttacaacaaa acgagctgaa ttccctattg aagaaggact
    28141 tttagctatt gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt
    28201 aggggatgca tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc
    28261 ttatcgtcct gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt
    28321 cattttcaca aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg
    28381 aaagaatcta gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat
    28441 ctatttattt gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca
    28501 atttatcgaa gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc
    28561 tttggtcaat ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa
    28621 tcttgaggaa cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc
    28681 ggcgcagttt caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt
    28741 cggctgtaat gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg
    28801 cggcgatttg aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt
    28861 ttctgatcaa aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta
    28921 caattatgcc tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct
    28981 ttggagaatc acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga
    29041 acatttacat acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc
    29101 taattaaaaa aggctctttg tcaaatgatg ttggtaaaga gaaatcttag aata
//
LOCUS       DAFBSV010000027        29094 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.028, whole genome shotgun sequence.
ACCESSION   DAFBSV010000027 DAFBSV010000000
VERSION     DAFBSV010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29094
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.028"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(56..1351)
                     /gene="purB"
                     /locus_tag="LLB18_001137"
     CDS             complement(56..1351)
                     /gene="purB"
                     /locus_tag="LLB18_001137"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBK5244151.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1364..2488)
                     /gene="purK"
                     /locus_tag="LLB18_001138"
     CDS             complement(1364..2488)
                     /gene="purK"
                     /locus_tag="LLB18_001138"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HBK5244152.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2481..2969)
                     /gene="purE"
                     /locus_tag="LLB18_001139"
     CDS             complement(2481..2969)
                     /gene="purE"
                     /locus_tag="LLB18_001139"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBK5244153.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3385..4692)
                     /locus_tag="LLB18_001140"
     CDS             complement(3385..4692)
                     /locus_tag="LLB18_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBK5244154.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4695..5276)
                     /locus_tag="LLB18_001141"
     CDS             complement(4695..5276)
                     /locus_tag="LLB18_001141"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBK5244155.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5392..5489)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5848..7140)
                     /locus_tag="LLB18_001142"
     CDS             complement(5848..7140)
                     /locus_tag="LLB18_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBK5244156.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7137..7760)
                     /locus_tag="LLB18_001143"
     CDS             complement(7137..7760)
                     /locus_tag="LLB18_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244157.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7763..8599)
                     /locus_tag="LLB18_001144"
     CDS             complement(7763..8599)
                     /locus_tag="LLB18_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBK5244158.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8616..9503)
                     /locus_tag="LLB18_001145"
     CDS             complement(8616..9503)
                     /locus_tag="LLB18_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK5244159.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9519..10802)
                     /locus_tag="LLB18_001146"
     CDS             complement(9519..10802)
                     /locus_tag="LLB18_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK5244160.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11485..12168)
                     /locus_tag="LLB18_001147"
     CDS             complement(11485..12168)
                     /locus_tag="LLB18_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBK5244161.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12186..12803)
                     /locus_tag="LLB18_001148"
     CDS             complement(12186..12803)
                     /locus_tag="LLB18_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBK5244162.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12813..13637)
                     /locus_tag="LLB18_001149"
     CDS             complement(12813..13637)
                     /locus_tag="LLB18_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBK5244163.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13630..14190)
                     /locus_tag="LLB18_001150"
     CDS             complement(13630..14190)
                     /locus_tag="LLB18_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244164.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14364..15320
                     /locus_tag="LLB18_001151"
     CDS             14364..15320
                     /locus_tag="LLB18_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBK5244165.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15625..16581)
                     /locus_tag="LLB18_001152"
     CDS             complement(15625..16581)
                     /locus_tag="LLB18_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HBK5244166.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16685..17287
                     /locus_tag="LLB18_001153"
     CDS             16685..17287
                     /locus_tag="LLB18_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBK5244167.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17375..18874)
                     /locus_tag="LLB18_001154"
     CDS             complement(17375..18874)
                     /locus_tag="LLB18_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HBK5244168.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18890..19414)
                     /locus_tag="LLB18_001155"
     CDS             complement(18890..19414)
                     /locus_tag="LLB18_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBK5244169.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19712..20461
                     /locus_tag="LLB18_001156"
     CDS             19712..20461
                     /locus_tag="LLB18_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBK5244170.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20452..21237
                     /locus_tag="LLB18_001157"
     CDS             20452..21237
                     /locus_tag="LLB18_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HBK5244171.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21206..21922
                     /locus_tag="LLB18_001158"
     CDS             21206..21922
                     /locus_tag="LLB18_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBK5244172.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22024..23058)
                     /locus_tag="LLB18_001159"
     CDS             complement(22024..23058)
                     /locus_tag="LLB18_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HBK5244173.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(23062..24120)
                     /locus_tag="LLB18_001160"
     CDS             complement(23062..24120)
                     /locus_tag="LLB18_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBK5244174.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            complement(24341..25489)
                     /gene="nagA"
                     /locus_tag="LLB18_001161"
     CDS             complement(24341..25489)
                     /gene="nagA"
                     /locus_tag="LLB18_001161"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBK5244175.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(25565..26401)
                     /locus_tag="LLB18_001162"
     CDS             complement(25565..26401)
                     /locus_tag="LLB18_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5244176.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(26585..27802)
                     /locus_tag="LLB18_001163"
     CDS             complement(26585..27802)
                     /locus_tag="LLB18_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBK5244177.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(27951..28130)
                     /locus_tag="LLB18_001164"
     CDS             complement(27951..28130)
                     /locus_tag="LLB18_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244178.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            28185..28268
                     /locus_tag="LLB18_001165"
     tRNA            28185..28268
                     /locus_tag="LLB18_001165"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:28219..28221,aa:Leu,seq:gag)
     gene            complement(28508..29086)
                     /locus_tag="LLB18_001166"
     CDS             complement(28508..29086)
                     /locus_tag="LLB18_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244179.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
BASE COUNT         8661 a         6226 c         5002 g         9205 t
ORIGIN      
        1 ttttttggtt atttttgcta ttctatttta attgaatttt gcaactcact cttctttatt
       61 ccaaacctac tcgtttgaat atcacgtcaa cgtttttcaa atgatgatga taatcaaagg
      121 catcgtctat ttcttcttta gataataccg atgtgatggt tggatcttct tctaacagcg
      181 ggcggaactg cacttggttg tcccaagcgt acgcagtttt tggctgaaca agatcataag
      241 cttcttctct tgtcattccc ttatcgatca atttcagcat aacgcgctgg ctataaatca
      301 aaccaaatgt tgcagacata ttccgcttca tgttttcagg aaagaccgtt agatttttaa
      361 cgatattgcc aaaacgattt aacatgtaat tcaataaaat cgtggtatca ggcaagatga
      421 ttcgttctgc tgaagaatga gaaatatctc tttcatgcca taatgtgaca ttttcatagg
      481 cagtgaccat gtgtccgcgc accactctgg ctagaccagc catattttct gaaccgatcg
      541 gattcctttt gtgcggcata gcagaagaac ctttttgacc tttcgcaaaa aattcttcta
      601 cttcacgtgt ttcggatttt tgcaatccgc gtatctctgt tgcaaaacgt tcaatacttg
      661 tagcaataag cgccatcgct gagaaatatt cagcatgtag atcccgaggg agaacttgag
      721 tagaaatttc ttgtggacgg atccccaatt gtttacatac atactcttca ataaatggcg
      781 ggatatttgc gaacgttccc actgctcctg agatttttcc tgcttctact ccttttgccg
      841 catgttcaaa tcgttcgatg ttccgtttca tttctgaata ccatgtggca agtttcaatc
      901 caaaagtagt tggttcagca tggacaccgt gtgtccgacc catcatcact gtatatttgt
      961 gttcttttgc tttttcgcca atgatttccg taaaacgttt caagtcttcc cgtaaaatat
     1021 catttgcttg cttgatgaga tagccataag cagtatctac gacatccgta cttgttagac
     1081 cataatggac ccattttctt tcttctccca atgtttcaga aaccgctcgt gtaaacgcaa
     1141 cgacatcatg gcgtgttaat ttttcgattt ccaagatccg atcgatatca aatgatgcat
     1201 gctcacgaat ttttttcaca tcttcttgcg ggatttcacc aagttctgcc caagcttcat
     1261 ctgctaaaat ctcgacttcg agccacgcac ggtatttgtt ctcttccgtc cagatattcc
     1321 ccatttcagg gcgtgtataa cgttctaaca tgttttttct cctctaatcc caaatattcg
     1381 tttgtttgat ttcttccagc gtttgctgga tgtcttctgt caagatagtg atatgtccca
     1441 tcttgcgacc tttttttgct tgtttttttc catagaaatg gaattgccag tctggcttat
     1501 tctcaatcaa gcgatagctt tccagcagtt gttctcccaa aacattgacc attactgcat
     1561 tgcttatcaa acgtactttt tctcctaatg gccaaccaca aatacctcga atatgggcat
     1621 cgaactgact catagaacaa gcttcaatag aataatgtcc agaattgtga ggacgaggag
     1681 ctaattcatt cacatatagc ccgcctgttt ttgttaaaaa catttctacc cctaaaacac
     1741 ctgaaaggct cactgcttct gcaatcacac gggcaatacg ctcagcctcc tcgatcacat
     1801 cctgatcaat cgcggctgga gcaatcgttt catgaagaat attgttgtgg tggatgtttt
     1861 ccacgaccgg aaaagtcgtg aaatctcctt gaccatttcc tgccaccatg atcgaaatct
     1921 ctttttcaaa cgggatccat gcttctaaaa cacaggttcc ttctcttaaa aggtccatgg
     1981 caggagctag atccgcccga cttttcaaaa catactgccc cttgccatca tagccgcctc
     2041 gagtggtttt caaaacacaa ggatagccga tcccgtcaat cgcatcttgg atatccgtcg
     2101 gactgacgat cgttgcataa ggagcaatca cgatgttatt cgtttccaaa aaagattttt
     2161 ctaacaggcg gtcttgcgta atcgcaagca agtctgtccc ttgaggaata aatgacatgg
     2221 gtaaaatcgc atttaacgcc tctacactga cgttttcgaa ttcataggta atgacatctg
     2281 ttcttctggc aagctctttc agcgcaaagg tgtcatcata gacactttca atgtgccaat
     2341 ctgcaacttg tgcggctgga caatcgctca caggatccag cacacctact ttaaagccca
     2401 tttcttttgc actaatcgcc atcatacgac ctaattgacc gccaccgacg atcccgatcg
     2461 ttgaaccagg caacaaaggt ttaaccaagt tgatcactac tttctataac agttttagcc
     2521 aacattgaac gtctttcagc caatttagcc tccaattcta aatcatacat ggaaagcatc
     2581 tgtatcgcaa gtagtccagc attaattgct cccgcttttc cgattgctgt agtagctaca
     2641 ggtactcctc caggcatttg gacaatcgaa agaagcgaat ccaaaccatt taatgttcgt
     2701 gattggaccg gtacaccgat aaccggcaaa gttgtttttg atgcgaccat acccggcaga
     2761 tgcgcggctc cccctgctcc tgcaataatg attttgattc ctttttttcg agcgttttgt
     2821 gcatattcaa acatcaaatc tggggttcga tgagcagaaa cgaccttttt ttcataagac
     2881 acaccgaatt catccaatat ttgacatgct tctttcattg tttcccaatc tgaagtactc
     2941 cccataatca cagagatttt tgctgtcatt gtttttcctc ccagtttttc tacattcata
     3001 ttttaacaat cacttttttt gatgtcaaag aaatttcgaa tgttaacaaa gaaaaacatt
     3061 ttattgttcg tgtttattaa agataaaaaa aaggaatgtg acaaaagtta ggtcacattc
     3121 ctttttatgg ataaacggtg ttctcctgcc aactcctcgg tcacaaggaa caatattcaa
     3181 caaacatgag aagctttttt ttgaaattgt tccttgtgac tcggagatga acggcaggct
     3241 cacgacctct tccttcaacg gtgttcaatc agctgaccct cggtattagc tcaaacaaac
     3301 ggcaaaatac gaggaactat ttttccgttt gtttctctaa caatcaggtc aaaacgctga
     3361 tttcacaacc tttcttttgc tctattactt cttgaaggct tcttccaata tttcttcatc
     3421 ttttttcaat ccattaaaga tcaaattcaa tatgatagcc gtaatgctac tcattacgat
     3481 gccatttcca gtgaacattt gcaatgtttg cggcatttga ctgaataatg tcggcgtaac
     3541 attgaaaccc agcccaaatc caacagaaac agcaacaatc aatagatttt tatcattgct
     3601 gaaatcaact tccaacagca tacggattcc ttggactgcc accatcccga acatgactaa
     3661 cattcctcca ccaagtaccg gctcagggat gatttgtgct aacgcaccga ttttagggaa
     3721 taatcctaaa acaatcaaga agaatgcaga gaaatagatg ggttttcttg ttttgattcc
     3781 cgaaagttga accaatccga cattttgaga aaagccagta taagggaatg tattgaaaat
     3841 accgcctaag ataacggcaa gtccttctgc acgatatccc tttttcaatt cttcttctcc
     3901 aacatttttc ccagtaatgt caccaagtgc aaaatataca cctgttgatt ctaccatgct
     3961 gaccatggaa atgatgatca ttagtaaaat cgaccatacg tcgaaagttg gtttaccaaa
     4021 ataaaagggt tgtggaacat ggaacaacgg cgcatctcca atcgcgctca gatcaatcat
     4081 tcccatgaaa gcagctaaga tgcttcctcc gactaaacca atcaataccg cgattgaacg
     4141 aatgaaccct tttgccagca tttgcacgcc tacaattagg agaatcgtca caaatgcaag
     4201 tagcagattt gttttgtcac caaaatcagc tgctgttgca ttacctccac ccattttctc
     4261 gattgctaca ggaatcaaag tcaaaccaat aacggtgata accgttcctg ttactatagg
     4321 agggaatagt tttttaattt tagaaaagac accagaaact aacacaacaa agatcccaga
     4381 agcgataata gatccgtaga tagctcctac tccttcattg gttccgatca agatcagtgg
     4441 agctactgct tggatcgcac atcctaaaac gacaggcaag ccaattccga aaaatcggtt
     4501 aactgtcaat tgcaataatg tcgctaatcc acacataaag atatcaattg aaatcaaata
     4561 agtcatctgt tcttgattaa agcctagtcc tgtaccgatc aaaagaggca ccgctactgc
     4621 tcctgcatac atcgctagca gatgctgcag ccctaaaacc gcagcttttc cattttgtgt
     4681 ttctttttcc acgattatgc gtcctcctca agaaactcaa cttgtccatt cgtcaaggaa
     4741 gcaatacgcg caagagaaac gactctcaat cccatttctt caagtaactg acgtccatct
     4801 tggaaagact tttcgatgac gatcccgatt ccttctactt gcgctccagc ttgctggcat
     4861 aattcgatca atccttttgc cgcttgtccg tttgccaaga aatcgtcgat aatcaatact
     4921 ttgtcttctg aagataaaaa tttacgagaa atagaaatcg tacttgtcac ttgtttcgta
     4981 aaagaataaa cagaagctgt caataattct tcatccatcg tcaaactttt tgcttttcta
     5041 gcgaagatca ttggaacatc taattctctt gcagcaaata aagctggtgc gatcccagaa
     5101 gcttcaatgg tcacaacttt cgtgattcct tgttctttaa atacttctgc aaaccgtttt
     5161 cccatttgtt ccatcaatac agggtctact tggtgagtga cgaagctgtc gacttttaat
     5221 acgccctcgc ctaatatacg tccgtctttt tgaatacgtt caactaattc tttcacttta
     5281 tttgctcctt tatcatttat taataccgaa ataaccgctt ttgtgcaaaa acctactatg
     5341 tttctgttaa agaaaaacac cctccacttt atcataagaa aagaagggtg aaatagccaa
     5401 tcttttactt atagtccagc atttacggta ctggctagaa actgtcatcc atattatgac
     5461 gatatataag taggtatgta aaactaataa tagtgtaaat tcattttctt gcaactgttt
     5521 tgcacgtgaa ggcagtttgc catatttgaa taaaaaatgt tgtttcaaat attgaaaaca
     5581 gtctaacact actttctgaa actgacaacg tggtttactt atttttttgt aaaatctaat
     5641 gatttttaat gcattattcc tttttgttcg ggtttaaata gttattttta ttttctccta
     5701 tctaaaaaag cagcccacat aaaaagaagg catgacaaaa agcatgtcat agcccctttt
     5761 tccgaataaa tagtgttcaa aagacagcct atcggcaata aggcaagatt ttataaacta
     5821 cgggaagtaa tttccgtaaa tctattctta ttcttttaag ctgacaagct cgtcaatcac
     5881 tactgctttt cctgaagcaa tagaatgatt tgctgcgatt cctgtcaaaa tcgacaaaat
     5941 accatctacg tgagttgctg cccgattcca cggatcttct tctttttctt caccaaatag
     6001 atcatctaat aaacgcggat ctcctccgcc atgtccgccc gcttcttgtt cgacgattac
     6061 ctcatatggc tcaccgaaca tcggatagac atggatggac tgaagaacgg ctgctccttc
     6121 atccttttta tctccacctg cattgatgta agacttttcg atcactttca tttcgatccg
     6181 tcctttgctg ccattgaaag aaacattgaa tccttcccac ggcatatacg cgtttagcga
     6241 atacgtcaaa atcgcaccag tttcatattt gaccgttacg cctagtgtat cttcaataga
     6301 gatatcatcg gaaaatacac tgcggtcacg aatatatcca ctgtcttttt ctgcttctaa
     6361 atacatttct cgcaattcct cattggctga caggtctata gcaaatggat cagctttagc
     6421 tagttcgctt ccatagcatc gactgtaaaa tatttctact ccgcgtttct ccgcattatg
     6481 catcccataa aagtttaatc caccgaatgc aaataccttt tggggacggc tgttcaacca
     6541 aaaattcact agatcaaaat gatgggtaga tttatgaaca agaagcccgc cgctattgtg
     6601 cttatttcga tgccatcttc tgaaataatc tgccccgtgt tgcgtattta acagccattc
     6661 gaagtggata gaaaacacat caccaatcac atcactttct atcagttcct ttatcttcgt
     6721 gtgatacggt gcataacgat aattaaaagt gactcgcagg cttcttcccg tctgtttttg
     6781 gaccgttatt atttcttgag ctttttcctc atcgatagtc agaggttttt cgcaaataac
     6841 atcatatcct tttttcattg cacgaatgat ataatcatga tgcgttcgat ctactgacgt
     6901 aataatgact tcagccggcc gtacgtcatc cagtagttgc tcaaattgtg atggcataca
     6961 tgtctttact tttttctgtc catacttgtt cacaagtatc cgatttgcat aatccatcct
     7021 tgtttgagat acatcacaaa aaccgactag ttcacaagtt tgatgatacg tagaggcaat
     7081 tgcctcataa aaaaaacgcg ctctcccacc aagtccgact tgtacatatt ttttcttcat
     7141 ttaaagtcat tctccttttc ttttaagcaa aatactgtga caaatggcag ccctggatac
     7201 agtaatgcag tgagtaaaaa atcatgctgt atacaccaga acagtccata caaaaggcat
     7261 aaataccaca gaaacccctt gacgtttttt gacaacagcc agatattcct tttgatcaaa
     7321 taaacaagac tatctgcttt atcttctttg cagatatcaa ttagcgtact aaaaaaacta
     7381 tgggatacaa aaagcaacag acacaataga aaaggaatca gataccaagc tccaatcttt
     7441 cccactaata aataccaatc aactgcaaaa ataatgacaa acagctgaaa caacgtaatg
     7501 atgaaacaca tccgtttgat ttttcctttc ctccaacata cctttttttc tgccaagtaa
     7561 tggacagata gataataaga aggatacatc atcaaaaaat aaatcagata gacaacacga
     7621 gcagacagca ctaatcctaa agtgaacaaa catcctagaa ctaaagcgaa aagagcatta
     7681 ctgataagac tggttaaaaa aatccgacag acatagtagt tgagcttgta aagaaacatc
     7741 tcttctattg gctttttcat attcagccct tcagaccgct tgtactgatc ccctggacaa
     7801 gatatttatt gaagaataag aaaatcagaa aaaccggtag cagcgacaac gtagacatcg
     7861 caaacatact cgcgtaagtc gtactagatc cagcgtctgc aaataatttg atggcaatcg
     7921 ataccgtgta agatctcggc ttgtttaaat aaatcaatgg tcccatgaag tcgtcccatt
     7981 tccaataaaa ctggatgatg atcgtcgtga tgatcgaagg tttcagcaaa ggaaaaataa
     8041 ttttggtaaa gacactatac ttgctgcatc cgtcaataat cgctgattca tctaactctt
     8101 tggggatgct gaccatgaat tgcatgatct ggtaaatgaa aaatgcttgt ccaaaaaaat
     8161 gtggtaaaat cagcggcaca tacgtcccaa ccaaattcag ccgattgtaa ataataaact
     8221 gcggaatcaa aatcacttgt gcaggaatca tcatcgttac taacatgacg acgaaccaga
     8281 atctttttcc tttgaaatcg attctcgata atgcgtaagc aatacaagtc gagctcagaa
     8341 ctgtccctat cgtcgaaact gcagagatga caaacgaatt cctaaagaaa gtaaaaaatg
     8401 aaattccagc aaaccccgcc catccttttg cgtaattttc ccattgaaaa gtctctggaa
     8461 tcaaattcag cgaaccactc ataatctctt gatccgtttt aaaagaacct gcgatcatcc
     8521 ataagaccgg ataaatcatg actagaccta atagcaaaat aaaaccgtat tgaaaccatt
     8581 tcgttactgt attattcatt tcttcctcct ctcattcaca caacgaccca tttttttgat
     8641 gatttgaaaa tcagaaaggt gacagctccc ataatcaaca gcatgatcca cgaaatagca
     8701 ctagcatacc ccatagaatt aaaagaaaaa gcttggttat acacataaag agcataaaag
     8761 ttcgtggcat cattcggacc accttgggta atgataaatg cctgcgtaaa agtcataaac
     8821 gccgcgattg tctgcataac caagttatac aaaatgatcg gcgaaagaag aggtaacgtg
     8881 atcttgtaaa acgtctgcca tttgttcgct ccatcgatct ctgccgcttc ataatacgag
     8941 cctgggatct ctttgatacc tgcagcaaag atgatcattg ccgaaccgaa ttgccaagca
     9001 gacatcaaaa caagagggat catgaccagt ttttgatcgc taaaccagga aagcgcaggt
     9061 gcgcctaatc gttccaggaa aatattcact aacccgtttt tagaaaacaa ctcccgccaa
     9121 actagagcga tagaaatact gccaccgatc aaactaggca cataatacaa agaacgaaag
     9181 aaagtcgttc ctttgatatt cctcgttaaa agataagcaa tcaatagacc aaagatcagt
     9241 ttcacaggta cagatgcaaa tacatagaga aaagtgactc ggatggagtt caaaaaacgg
     9301 gcatcactca gcatctttat ataattatcc aagccgatcc atgagactgg atttcccaaa
     9361 cgataatcgg tgaacgaata ataaagtgac aagatcatcg gtatcactgt tatcaataga
     9421 aatcctagga tgaatggaga agcaaatacg taaccgacca cattgtcttg atccaagaac
     9481 cgttttagtt tttctttttt catgccttcc tcctgctgct atcctagaat gtttgacgca
     9541 aactcataaa gactctctgc tgcttcttct gctgttactt cttcataaat gactttttca
     9601 actaaaagat tgtattggtc ttgaatttcc ggattcaaag cactatcaaa gacattcact
     9661 tcgccgttgt ccatatcgga aatcatttct aaataatcaa atgtcgcttg caaagttgca
     9721 tcatctgcac gagcgagctg ttctcgaata ttcgacatga ttggtacacc acgttctcct
     9781 tttaaaattt cattggcttc ttcactgttt tgaaagaaat caataaactt agcagcttct
     9841 tctttatggg ctgagctttt tgccatactc agcatttgcg aagaacgtaa agggatacca
     9901 gattctccat ctgcttttct gcgaggtgga ttaatcaact gaatctccat atcttcagga
     9961 gcccctgaca atatttctgt caactggtta cttgatagaa acaccattgc cgcttctcta
    10021 tccctaaccg cctgaaaaga cagatccgtc gtacttgcag ctccaccacc tggttctgga
    10081 tgggcccctt tgtctaccag atttttacgc agctggaaaa aatctgttag atagtctgga
    10141 ttttcaaatc ccaagctgtt agatagatct tcccgattat aaaaattcaa tcctttctca
    10201 acttgtggta tttgaataat acagccagct ataaaatctt cgaatcttga aatagcatag
    10261 attcctaatt cttcagtgat ttgatagctg atttgttcaa attcatccca tgtccaattt
    10321 gaagctggtt cagggatatt taattgttca aatatatttt tattgtaagc aatcgcaaac
    10381 gaattcaccc cgttagacag tccaactaat tgcccgtcgt aagtcgtcgt tgctaaatag
    10441 gattcatctg cattagaaat atcaattatc ccttgctcca catattcatc taatggttca
    10501 atctgattga tgtattgagg aaattgattg ttcagttgga aaatgtccca gatatcatct
    10561 gatgctgcta gtgtacctaa ttttgtgtaa tatccttcat aatcataaaa ttcataatcg
    10621 atcgtcacat ggggattttt ttcttcataa agctcgatta cttttactgt tgcatcgtgt
    10681 cggacttgcg aaccccacca agccatgttc agcgtgattt ttttgtcatc ttcttgccca
    10741 caagccgtca agaagaataa cataacactt aaagctaaga tgattctcat tcttttcttc
    10801 attctctgca cctctacttc cattgttatt tttcaatata ctgtattttt atacagaaca
    10861 tatttattaa acgatctttt tcaaggggaa taaaaaccaa gacttgcctt atcgttctgc
    10921 ctaggatgaa caactcaata ctttcaagaa aaattagata gtgctgattc ttctttcatc
    10981 gctaaaaaca cttcttgctt caatgatggg aggataatta cgcaaagaaa aaaggatatc
    11041 agacaactgc ccaatatcct tgacatagct aaataagcat gcttcttcgt gtgcgctctt
    11101 ccctaaaaaa cagaaaaata actagtaatt ctgtatgaaa ttaggtacaa tatacacgtc
    11161 gatgcacaag cattgactat ggcaacttga ttggtcagtt cccgctgact tttcaagccc
    11221 cgacaattta gctgctacta aattgtcggg tgcctttttt agtttttatt cgtttttcat
    11281 tctatagaaa gcgcttcaat aaatcaagac atttttttgt tagaatgcta ataataacaa
    11341 aaggttttaa ctcttcttat gtacattaca ggtaaaaaaa caaaaaaatt tctctttttt
    11401 ttgaattctg aacaaatagt actggagtac aaaagacgag gaagagccac tatctgctct
    11461 tcctcgtctt ttgattctca cctgttattc atgattcttt ttctcagttt cccgatattt
    11521 ttccatttta cgactaaaaa gctctccgct acttggtggc gtatatgtga tggcatttgc
    11581 tcctgcttga atggtctcag caatactttc ttccgttgga ccacctgtcg caatgatagg
    11641 aagttcagga tattttttac gaaaatggcg tactgcttct gcagtttctt tacctgcact
    11701 gatattgata atcgaaatac cagctgctaa cttttcatct atttctgtat atttcgacgt
    11761 taccgtactg ataactggaa tatcaactac tcgacaaact tcttttactg tctctaaagg
    11821 cgtaggaccg ttcaaaacga cccctaacga accttgcgct tctgcgaaca tgctcatgta
    11881 ggaagaacga gcaccttgtg tcaaaccacc acctacaccg gagaaaactg gaatgtcagc
    11941 tgcctcaata atgcttttag taatcgctgg atgaggtgta aaaggataca cagcaattac
    12001 tgcattcgca tttgtattac gtatgatcgc aatatccgta gtaaagatga tcgaacggat
    12061 caattttcca aatatcttga tcccgcttgc ttctaaaatg atttccggta ctcttacgat
    12121 atcttttctc aattccgtca tgatttctgg cgtaaattgt tctgccatca gccacttctc
    12181 ctttgctatc tccggtcata ctgattcaat tgatacgtct cgatgacctg gatgattttt
    12241 tgcgcataac cggggtctgt cgcataacct gcatcttgca atgcttgtgc ggcttcctga
    12301 tagttggtgg ccgtaatcac tttttcatac agcgcaggat tccaatctac tccttggacg
    12361 aacagttgtg tatggtcatc catggactgt tcccatgaat catacacttt gaagtctcct
    12421 tggatagtta tccattcttc gttaacaaat tcctttgttt ccaggcttac tttcttctga
    12481 tccccataag ccttgatccc gaaaagatta ttgtatttgc tagccaaggt actttttccc
    12541 caatttgatt ctaatatagc ttgtcctaaa atgatactag gaagcactcc ataaccatct
    12601 tgtagttctt gggcatgcgg aacaagccgt tcaataaatt gctgatggga ttgcgcttca
    12661 ttttcttgct gattatcagt aaaaggagaa gacagattct tcaaggaaaa aacaaaggct
    12721 aagagtatca ctgctacacc ggcaaccact gctggccaac ggatattctt gcgcttttgc
    12781 tttttccact tttttttcgc catgatcaat tcctactttt catttaattc attcagatat
    12841 tcttctagcg tcaattggtg tttggtgata tactcagcgt tttctttacc gacataacgt
    12901 aagtgccaag gttcatatgt gatcttagtt atatcttcgt gtccttttgg ataacgaacg
    12961 ataaatccat actgcgcagc attatctgcg atccatttag ctccaggctg atctccgtaa
    13021 cttgcatcca atacagtaga aggataactg ttgtaccagt tttgatcgac gacatcgact
    13081 gccagacctg tgtggtgttc gctgtatcct ggctccgtaa tcgtttcttt agtaatcttt
    13141 gtcgcctcct cttctgatac accttgacga ctcatcacat cttggacatt ttgttcgaaa
    13201 acttgttgtt gggatgatac agaccggtaa gctgagacca tcactaatgg aaatccagct
    13261 gcttcagcag ccttggcaaa tgcttcatat tctggagcaa tgcgtttgtc gatcaagtat
    13321 ccgttactta atgatgccaa ttgagtagac tcatcaattt ctttttctaa tttgtgatct
    13381 ggaccaacca aaactagctt ccaatcgtct gttttaacat ctggcaattg tttggacgta
    13441 cgatcttttg tttctttgtc ctttaccttg ctgctggttg tttgactgtt cttttcttta
    13501 ctagcagttg ttttggtgct tgttcgttcg actgcttgat tgccggcttg aacatgcgaa
    13561 tcatcatcgc taaaaataac atagcccatt gctgcgatca taatcacaac tgctccaaat
    13621 cctaaaaatt tattcacttg aaaaatcctt tcgttgttct tcacgttccc cattcgcctc
    13681 atgaacgtaa gtttcttcca gattttcatt cacccaatcg agaagttcga ttttttctcc
    13741 ttcgatctgt ttttgaacat ctgctggcag acgaaaattc aaaatatcat catagcccca
    13801 ttcatcatat tgaatactta ctttcaagtc aaggtatcta ccagcctgct gattattttt
    13861 caaagggatc agctcgactt ttgctgcttt gctgctaagc catttttgcg cgatgcgtgt
    13921 tttgatttgc ttgtactctg caacggcaac gtttcgtttt tcgggaaaaa taatcgtttg
    13981 acgcaaaatc ttttgcgtta gcatccattc ataatcagtg aaaagatttt ttactttctg
    14041 catcgcttca gatggcagat ttttctcgcc atctttccat ttttgccatt gttctggact
    14101 gatcagcaag tattcatcta aaaaattttt ttcagtttca aactgttcta ataatacact
    14161 cataataaga tcaatatata cttgatgcac gtttatcccc tccttttaac tattctactt
    14221 aagttttgat caaaaagcac ctcttaaatc gctgctttca ttttttttaa tgtttcaagt
    14281 cctctcctct ttattcttcg tgatttttgt tataataata gacagacaag aaactcaatc
    14341 caactatgaa ggagcgtttt cagatgaaaa aatatcaatg gggaatcgtt ggtcttggta
    14401 ccatcgcaca tgagtttgcc gaaagcttca atcaagagac gagcgaacta acagcagttg
    14461 cttccagaac ttcagaaaaa gcggaaaact tcgctcaccg ttacaatatt ccaaaagctt
    14521 acggaagcta tcaagaaatg ttagacgatg ctgaaatcga catcgtgtac attgctgtac
    14581 caaatagaca gcatatcgac catatcttgg cagcattgga agcaggcaaa cacgttctat
    14641 gtgaaaaagc catcacgatg aataaaaaag aactggctga cgctatgcgc ttagcagaag
    14701 aaaagaattt gatcttagca gaagcgatga caatcttcaa catgccactt tatcagcagt
    14761 tacgctcaat aatggataca ggaaaactgg gggctttaaa aatgatccaa gcacctttcg
    14821 gcagttacaa agaaccagac cctaaaaacc ggttcttcaa tccagaatta gctggaggag
    14881 ctctgttgga tatcggtacg tatgctgtat ctttcgctcg tttctttttg agctctcaac
    14941 ctgaagtagt tgcctctaca atggttcctt ttgaaacagg cgtggacgaa caatccgtca
    15001 ctatcttgcg taacaaagaa aatgaacttg ctgctgtcag cttgactttt caggcaaaaa
    15061 tgccaaaagt cggtatcgtt gcctttgaga acggttatgt gacgattgct gattacccgc
    15121 gtgctgatcg tgcggagatc ttatttacag atggtacaaa ggaattcatc gaaagcggga
    15181 atacatctga agcaatgaat tacgaaataa agaatatggt acacatgatt gaaggtgact
    15241 tgcccaatcg ctctctcttc ttgacaaaag atgtcatcga aatcttggat caaatgcaag
    15301 ttctatggaa aaatatgtaa ttttaaaagg ttgtgaaaaa gctgttctgc atcaagtaat
    15361 aagaacagcc aaacaaaaat agctcctcct atttttcgtt tggctggact tattaccgca
    15421 gaggaaagct tttgaacacc gtttaagaaa gaggttgtga gcctaccgtt cagctccgag
    15481 tcacaaggag caatttcaaa aaacagcttc tcatgtttgt tgaatattgt gacttgtgac
    15541 cgaggagttg acaggagaac accgtttaaa gaagaggttg tgaaatcagc tttttgacct
    15601 gaatattagc tgaattcaca acctctattt ttggattttt tgttgggaga attctgcctt
    15661 gatttcaata aaacttttaa aagactgcaa aaactggaac aattctgctc gatcctcgaa
    15721 ttcagggcga ctagtcggca gaggcatttg ccgatacaat acataaactt cttcaatacg
    15781 tgttaaaatt tgtctgccat catttgactc tgaaaatgtt tctgcagtat aaatcaataa
    15841 accatagata tgttttccat aataagctgg ttgctggatt ctctctagat tttccagcat
    15901 gtctttaatc acattggcct gtgctcttct catagagaag taagtttcgt agtatagcgg
    15961 ctgtctgagc cagtagtttt cttgatgttc tctggcatct tcttggcttt cgcgaatgaa
    16021 tgtcagtaaa tgttcgcatt tgatctgcac atcttcttta ttttctgata aaagaaattc
    16081 tgccatttgt ctcaaaatat ttcgaaattc tttttcgatc tgtatttggt tttccttcag
    16141 ctgcttcgta cgatctggca tgtaaacatt tgcaagcaaa gcaaatacta atccaatcgc
    16201 cattaatccc gcttcattgc cgatcagctg ccaagacatg ttttcctcca ctaaataatg
    16261 agtgaccaaa accgaattta ctactatccc ttcggttaat ttgaagcgag aggcaagcgg
    16321 gatgaacagg aataaaaaaa gactgaagcc aaaaatagta tacccaacag caaaaaaact
    16381 gaacagtgct gttgccgtag ctaatataaa ggctgcgatt cgattcatgc ccgtacgcaa
    16441 tgtagagcgc ttggtatttc ctacacttaa taatgcaatg atccctgcag ctggccaata
    16501 caacagcgat aagctacccg ctgtgaccat cgaaaagaag acactgatca ctgttttgac
    16561 tgttcgcatt cctatacgca tttacttccc ccttttttat tttaattata cttgaataat
    16621 gaaaaactag ctatcagaca aaagtttagg tatgatagta aaaagaccaa aaaggagaat
    16681 ctctatgcaa tttggccgtt ttcgactagg tatgcgtacg atcaaaagtg ccttagctgt
    16741 ttttttatgt atcttgtttt ttcatttgac tcaacgagga atcccgatga ttgctgcatt
    16801 atctgctgtt ttttctttgc gtcaggactt gactacaacc gtttcttttg gaaagtctag
    16861 gatcatcggc aatacattag gtggtacatt agctatcatt tatttttttg tcaaaagcta
    16921 ttttcacaat gattttttgg tagaattgat cttgcttcct attctagtta ttattgtgat
    16981 cgtcgtgtca gatggtatta acaataattc cggtatcatt tccgcaatag ctacgttgtt
    17041 gctgattgcg ttgagcatcc ctcaaggcga atccgctttg tatgctatcc aacgtgtact
    17101 agatactttt atagggacat tcattgcaat cggtatcaat ttctttcttc gtcctcctga
    17161 aacagaaaag aaggaagaac tatcagaaga tttggtcgaa ctccaaaaga aagaacgatt
    17221 gctaagaaca aatttacaag agatagaagc taagatccaa aaacaaaaga aaaatagcga
    17281 ggactaattt tcttttgcaa taaaataaaa aaatggagag aagaacttta aaaagtcttc
    17341 ctccattttt gattgaacgg tgaagtgtac tactttattc ttccttcatc gagttttgtt
    17401 ctgcctcttt tggcgcttca tacatattta cttggctagt agtcccacgt gtcgacaaat
    17461 tctctacgat ttccttcaag tcaagtcctg ttgtcgcttt tagtgtttct tgagtagaag
    17521 aaagcaaatt tgtggcataa tttgtcactc ggttcgctcc actggtttct cctgaactgc
    17581 ttcctgtatc gacaacagag attttttcga tatttcctag cggctgtgct gcttcgcgca
    17641 tcaattgcgg tagcatatcg ataaccatac tcaagacagc tgcttcgcca tattccttga
    17701 aggcattggc gatcttttgt tttgcttcgg cttctgcttt tccttttgct agtgctgctt
    17761 cggcttctgc ttgtccagct aaacgtgtct tattggcttc cgcttctgcc agtgcttcca
    17821 cacggaatcg ttctgcttcg gcttcagtca cttctttgac tttttgagct tgtgcttctt
    17881 gttctttagc gtaccgatcg gcatctgctt ttttcttcac ttccgaatca tattgctttt
    17941 cacgacgtgt gatttctttt tcttccagtt cgatttgttt ttgacgttct acgattttaa
    18001 tctgcatttc ctgttcgatt acttgttgtt gtgctcgggc actttctaaa ttgtaggctt
    18061 ggtctgcttt tgctttagca acatcttgtt cttgtttgta ggttgctaat ttcagttctt
    18121 tttcttttaa tgattctgcg atctctgttt gtcgctgtaa ttcagctgct tgtgattctt
    18181 tttctgcttg agcttttttg atacgcgttt cttttagagc ttccgcttct gctatatctg
    18241 catctctttt gacttgggcg attcttggtt tccctaaaga gtcaagataa ccgtttttgt
    18301 ctctgacctc tttgatagtg aaagaaacga tgatcaaccc catttttgca aggtctacag
    18361 aagcgacttc ttgtacgctt tgactgaact tatcgcgatt ttgatagatt tcttctacag
    18421 tcatagaacc aagaatcgag cgcaagtgtc cttctaatac ttctcttgct tcattttcca
    18481 gttcttctct tgtcttgcct aaaaactgtt ctgctgctgt agcaatctct tctacagatg
    18541 aaccgatttt gatgatcgaa gtaccatcac acatcaccgg tacgccttgt tccgtataca
    18601 cttcaggggt ggagacgtcc aatttactcg ataatagact gatccgattc gaacgttgaa
    18661 aaactggcaa gacgaatgcg ccacctccac gcacaatttt gattttgtta ttgctttcat
    18721 caatgtgcac atttttgctt cctaaataac ttccactgat gatcaacgct tcatccggtt
    18781 ttgctgtctg gtacttcgct acaaagacga tcagcaacat cagtaaaatc aaagctgcga
    18841 ttgcgatcgc gataaaaaca actggtattt ccatttaaca cacgctcctt taagctttta
    18901 tcatgctttc ataaggcatg acataacaga ttctttcctt gatctcaatg atcaatactt
    18961 tcgttccccg ctcagctgtc tgttcttggg ggctgtaaaa acaagctgga cgactaatgg
    19021 aaccggtaac acttttcaac tgaatttctc ccatacctcg tacagggatc ggtgtgatca
    19081 caacagctac ttgtccttcc agagtttttt cagaagacga catcgttgat tcggcatgtt
    19141 tcatcggcat caatatatag aaattaagca aaaataccaa cactatcgat atgcctccac
    19201 tagcaataaa taaaaataaa gatgattgat ctgttaaacg ctcacctaga aaaccaaata
    19261 agcttgtgaa agttaaccaa gggataataa gcatcggatc aagcgggcca tcaaaatcga
    19321 atacatctcc aaaaataatc aataggactg ccaatcctgc acaaatcagc aatgtatacc
    19381 aataaatcgt ctcaagtgcg attcccccta tcatatacac gcctccttcc atttctacgt
    19441 ctatcatacc aatgtttgaa aattctgtat agcttctttt accgactcag tggtgttttt
    19501 tataggaagg ttgtgtttat cgttgacaat ttgttaaatt tttgttttca tgttaaaatt
    19561 ttcacaataa attctttcga ggtagcctat gtttcctttt tttaagaaaa aaccattaaa
    19621 gctccagaac acgatcatcc ttgtcgtttg tttctccaca ttcgtttctt tgattgtttc
    19681 tgccatattg atcaggaatt ttattctttc gatgaaccga tctagtgtgt cagataaaat
    19741 ctctagcatt gctaaaatcg ttgccaatga taaactcatc caaaaaaagc tgcagactgg
    19801 tgacccgaca catgcgattc aaggaataac aaatgaaatc atgattgcat cgaatttaga
    19861 ttttatcgtt gtcatggacc ctgaaggcat tcgatattct cacgcagacc caagttacat
    19921 cggtcttcct ttctcaagtc atgaagatgt gaaaaaagtg attggaggac aagaattttt
    19981 ctctgaaaaa gaaggaatgt tagggttcgg cttccgctat ttcgtcccta tttattatga
    20041 tcaagagatt attggtgcag tttgtgttgg cttaacaaac aacacgattg acaatcaagt
    20101 caaagatgga caaaaaatga ttgttttttc attgattatt ggacttagcg taggcatcat
    20161 aggcgccgtt tttcttgccc aaaaaatgaa aaaagtactg cttggacttg aaccacaaga
    20221 aatagcagaa cagttaagtg aaaaaacgat tatcgaaaat gaagtagatg aaggaatctt
    20281 agccatctct tctgataaaa ctatcctctt gatcaataca cctgcaaaaa acattttcta
    20341 ccaaacagag cagctattgg atttcgaagt aggaaaaaaa tcagtgataa tctatatgac
    20401 gttttgttta aagagacgat tgagcatcaa acgaccgttc ggactcaatc catgtattta
    20461 aatgggatag aaactatttc tagcgttaca cctcttttta gcaatgaccg ttttttagga
    20521 gcagtcgcaa ctttacgaaa tcgatcagaa gtaatgaaat taatggagga gcttgggggg
    20581 acgaaacaat atataaactc catgagagct caaacccatg aattcatgaa taaacttcat
    20641 gtcatttctg gtttgattga tttgaagaag tatgaagaag tcacccattt tatccagcag
    20701 ctaaatcaaa attataaaaa agagattggc caagtctcaa gtctgatcaa agtacctgca
    20761 attgccggtt ttttattagg caaaataaac gaagccaaag aacaatctgt tgaaatgctg
    20821 ttagaaagcg attcttttat ccctaaaatg gagatggatg actccatcca ttcacttttg
    20881 caagtgttag ggaacttact tgataatgca aaagaagccg tgctacaaaa acatgaaaga
    20941 aacggacagg tccggattca tttaaactat gacacagaag ctgaagtatt catcgtgacc
    21001 gtctgcgatg acggtgtcgg gatatcagaa gaaatctcag aaaaaatatt tacgctaggt
    21061 ttttcgacga agggaatcaa tcgtgggttt ggattgaatc tcatccattc aatcgtcaaa
    21121 cgccacggtg gatttttaga attttccaaa caaacaaatg gcggtacaat cgtctatcta
    21181 gaattaccaa aaaaggaaga tcaaaatgat gacaaatgtc ctgataatcg aagatgatcc
    21241 aatggttgca gaattgaatc gtacttttgt ggaaagcatc cctaatatga acgtaatcga
    21301 aagtttcaga aatgtagaag aaggaaaaaa atatttcaga caaaaaaacg cagatctgct
    21361 gctgcttgat gtatacatgc ctggcgaaag tggtatccat tttttatctt ggcttagaca
    21421 gcaaggaaat gatatcccag tgattttgat cactgctgca gatgatatcg aaaccataaa
    21481 gaatgtgatc cgctacggtg ccttagatta tttgatcaaa ccgttcactt tgcaacgttt
    21541 tcagctggcg atcgaaaagt atcttgcttt ctctcagaca atccaaacga ctgaaaaagc
    21601 cgatcagaaa ttgatcgatc aagtattcaa ccacaccact cccattcacg aaataccatc
    21661 attcatcgat ttgcctaaag gtctgtcaaa actgacttta aaaaaaataa gtgcatttat
    21721 tctaaaagaa gatactattt tttcaacaaa agaactggct caaaaaagct cactgtcacg
    21781 tatatccgtc aagaaatatt tgaatttttt agtagaacaa gatatattga acgaaagaat
    21841 caaatatttg gaaatcggcc ggccgctaac ctgttatgaa ttgacaaaga atgggcggaa
    21901 aaagctcaca gattactgtt gagtcatcga attatcccat acaaaatagt ccaagtatac
    21961 agaagtaaca actgtttact tggactattt ttaaacattt tattgacgaa tatccatgtt
    22021 ttcttatctt aattgacggg ctttaggaag agatacctca tttttcgttt ttccagtttc
    22081 tattatttca cgaaagttct cgaaacttgt cgaaatcata tttgataatg cctcatctgt
    22141 atttgaacct acatgcgggg ttacaagaac tctagggtac atttctacta attgctggat
    22201 agcagggtct ggaatcgtct cccatggctt gaaggatcgg aaaaaaacct ctgtttcatt
    22261 tgcaaaaaca tcggttgcaa aaccagctaa atgattgctt ttcaaagctc ttaaaatagc
    22321 ttcattatct tgaagctctc cacgggctgt attaatcaag atgctacctt ttttcatttg
    22381 agctaaaaat ccttcattga tcatttgatc gttttcacct gggatatgag gtacatgaat
    22441 actgacaata tcgcttttgg ctaataactc ttcaagcgag tggaacgtca atactttttt
    22501 agcagcttct gtctgatgaa tatcgtagcc gatcactttg gctcctagtc ccttaaacaa
    22561 aacagcttcc gtcaacccta tcctgcctgt tcctatgatc cctactgtgc aatttctgat
    22621 ttcacgacta aacatttgct catccactcg aaaatctttg aaagatgttc ggatcgtcgt
    22681 atacgcagta tttctcaaaa gcatcatggc aaaagtcaaa gataactctg ctatcgcatt
    22741 tggcgaatac gatggtacac gggctactgt cataccaaaa tcagctgccg cttgtagatc
    22801 gatatgattg actcccacag tccgtgtaaa aacataacga atcccatatt cctgcatttt
    22861 tgcaagattg gtctcatctg ctatacaatt tcccctcaac aatacagcat catggtcctt
    22921 tgctgacacg atattgtcat gtgtcaacag ttcttcataa agactgagat cataatggta
    22981 aatattcaat ttttcaaaaa aatctatctc gttcggacga acaccgtaac atgcgattct
    23041 catactttct tcctccattt cttatgaaaa taaacctatg ccatgaatca tttgtaatac
    23101 aacgatccat acaggtgtca gtaccacagc aaaaatagtt gacagtaagg atgcattgga
    23161 ggctaaaagt gcctccctat caaaactgat agcataggct gctgccactg ttgcagctgg
    23221 tgtagccatc atgataacga ttgttgccag tgcttcaaaa ttgactggta gaatattcgt
    23281 tgccgtcaaa actgctagaa tcacgatatt caatgcaggt acaaatacca ctttgactag
    23341 actgtaatac catgaagttt tttcagatgc agcttttttg aagcttactt cacctaatgt
    23401 tgcgccgatt gctagccacg ccaatggtga acttaaacca gctaaataat ccatcggctg
    23461 aaatagccac ggtgcagtct ggtcaattcg caaaaacgct acttggctta tctctccttc
    23521 tgcacctgta actgacactt gtggcagata cccttggaac agccaaatga aaaggccggc
    23581 aaaagtagcg ataatgattg gattgacgaa catcgctttg atatttttag cttccatctt
    23641 caagccactc atttttatgt atccataaga atacaaaaag attcggtagc caatattgaa
    23701 aattgaggaa tacatcacgc cgacaggacc ataaatcgca ctgacgatag gcgttccgaa
    23761 aaaggtcgta gaaccaaaga tcgtcaggac acgcaacgtt gtttgcttat cccctttata
    23821 gcttaagaaa aaaggttttg aaactagaat aagaataata taaataacta atccccaaat
    23881 caagacattg attccttgca tcagtaattc tgtattgata tcttgcatga aagctcgaaa
    23941 tgccagtgct ggcaaagcca ctgttaagac gactttcgat agaatttttc caacagattc
    24001 agaaaaaatc cccttttttc tacaaacaaa ccctaataat ataataaaaa ctgttgaagt
    24061 gattgcactg acaatcgaca tatctgtcaa agtcgatcga aaaatgtcaa ataagttcat
    24121 ctttctcctc ctaattatgt tcatttattc acaataaaaa aagcttttat tttgctaata
    24181 cgtattaaca tttttaattt tatctttaca ttgttactta ttgaacaata ggaaattaaa
    24241 gaaacttttg aaacttatgt aaagtgattt ttactagaac acaaaaaaaa ccttaaaacc
    24301 aaacttaaga agtttagttt taaggttaac ttaaattata ttatgcgtgg aaacgttcca
    24361 cgccatctag ataagttgct tccaatgtca tatcagggtt caatacgata aagtctgcat
    24421 cgcgtccttg agcgattttt ccacatgtat catcgatttt acagctgatt gctggaatca
    24481 gactagccat catgactgct tgttctggtg ttgctaatcc ccagtctaca acatttttaa
    24541 ttgcttcttt caatttcaat atacttccag ctaagttgcc agattctaga cgtgctgttc
    24601 cttcttttac tactactgga aattcgccta aattgtaatt tccatcaggc atcccaccgg
    24661 ccatcataca gtctgtaatt aatgcgacat gatcatgtcc tgctttttcc attaggattc
    24721 ccgcagcatt tggatgtaca tgatggccat cacaaatcaa ttcagaaaag acatgttcta
    24781 aagataataa cgcacccacc atacctggtt cgcgatgatt caatccacgc ataccattga
    24841 aagcatggac aaatacactt gcgcctgctt caacagcttt ttgcgcttct tctagtgtag
    24901 cattactgtg tcctagagaa acaactactc cttcttcagt cacttgtttg acaaactctt
    24961 ctacaccttg acgttccggt gctaaagcaa tttttttgat taaaccacct gaagcttctt
    25021 gccattcatg gaaagtatcc aaatcaggat ccccgaaata acttgggttt tgtgcccctt
    25081 tgtgttcttc tgtgaagaaa ggaccttcaa aatagattcc tttgatttta gctcctggtg
    25141 cttcctgata cattttgccg attgtctcag ctacatcttt taaacgttct ttgcttgacg
    25201 tcaatgttgt tggtaaaaat gaagtcactc cacaagataa cagaccttca gacatcactt
    25261 tgatgccttc tgcatcatta tccattacat catgattcat atagccgtga atatgtgtat
    25321 ctaccaaacc aggagcaatc catttgccgc tttggtcaat gatgttgact tctccctcag
    25381 gtagttcttt ggtgtattca ccaaaaagtc catcggtaat ttcaagatag cctgcatgtt
    25441 tgacacctga cgctaaaaag aatttgtcag catagataaa agttctcatt ctattctctc
    25501 cctttgtttt tctacctcta aagtactctt atttagagaa gaagtcaaga atggtctaca
    25561 ccatttacaa attttttgaa atttgtttca cagcttgtgc taagccttca tagaatgctg
    25621 ctctttctgg ttcttcttta cgcttgtata ttaagctttt aagcacaaat aaatcattga
    25681 ggtaatagta gctattcttc tcttgagccc aatagattcc ttgattcacc tgttctaacg
    25741 cttcgtcgat ttcattttga tggaataaga aatttccata attataaaaa atttgcgaaa
    25801 attcactttt tgatcgttca tcagctgatt gatgcagcag ttggatgctt cgactcaaat
    25861 agtagcgtgc ttcagccgtt tttcctgcca caccatatat ttttccgata caactaatca
    25921 gttgtatttc tgtgtcagaa acatggattc tttctttttg gctagagtag cttaatgctt
    25981 ctttcaaata ataaagggac tgagagatat tttgacgcaa cgtgaattcg caaacaccga
    26041 gataataata atagcgttga aagtcagttg cttgatacag attttcagaa atatcagaag
    26101 attttagtac ttgttctaac ttccgataat cacgtttttg gaaacaacta tccaacagtt
    26161 caaataattt atcgtttgtc cgagtagttt ttcgagagag attcatcaca tgatcaatcg
    26221 ttacccctag ccgttgacaa atctgcatca tcaccaatac attcggcagt tcctcattat
    26281 tttcgatccg acttaataca ctttgtgaac aaatatcatg cgaaagcatt ttttgcgtca
    26341 ttttttgttc ttttcgaatc tctttaatga tcgttccaaa ggactcgatt aacgtttcca
    26401 taagtatcct ccccaaaata tgcgtattcg cattctattc gtattttact ttaggaagtc
    26461 gcaaacttca agaaaagact tgcaactaaa taatatactt tagttattta agaaaactcc
    26521 actagaaaga gagcctcagt gtgtttgtct gtggccctcc tactgaaaaa tttggttttt
    26581 aaaatcattt ttggcgatag gttgctagga attctctcat tttcttagct gtttgtttca
    26641 aatcatccat tttaggaaga taaacgattc gaaaatgatc tggctggttc caattaaatc
    26701 caccaccatg tacaagtaga atatgatgtt catgtaaaaa gtccaaaacg aatttttcat
    26761 catccaaaat attgaatcgc tttgtatcaa tttttgggaa tatataaaaa gcagcttttg
    26821 gttttacggc tgaaagacca ggaatatcat tgattgcatt atagatatat tctctttgtt
    26881 catagatcct tccgcctggc aggagcagct catcgacact ttgataaccg cctagcgcgg
    26941 tttggataat ttgctgagac aatacattgg aacacaaacg catggaggac aacatattca
    27001 gcccttctat atagcctttg acgtgtgact tatctccact taggaccatc cagcctactc
    27061 gaaatcctgc tacacgatga gatttggata gaccgttcag cgtaacaacg aacaaatcag
    27121 gcgctaatgt agcaatcgga atatgttcta gaccatccat cactaagcga tcatagattt
    27181 cgtcggaata aataatcagg ttattttgtc gagctacttc aacgatttct tctaataatt
    27241 cttttggata aagtgcccca gtaggattat taggattaat gataacaata gcttttgtcc
    27301 gactcgttat ttttgatttg atatcatcaa tatcaggata ccattctgcc tcttcatcgc
    27361 aaatataatg aacaggtgtg cctccagcta atgcaataga agccgtccac aacggatagt
    27421 ccggcattgg aaccagtact tcatctccat tgtccagcaa cccctgcata cacatcgtga
    27481 tcaattcgct cactccgttg ccggtgtaga tatcattgat cgtcacattc ggaaaatgtt
    27541 tcagttggca atattgctca attgcttttc tagcagaaaa gatccccttg gaatctgagt
    27601 agccttctga gtcacgggca ttcatgatca aatcacgaat gacttcgttt ggtgcttcaa
    27661 atccaaaagg tgcgggattt cccgtgttca attttaaaat actaatgccc tcttcttgca
    27721 tccgctccgc ttcttctaga acgggaccgc gaacatcgta actgacacct tctaatttgt
    27781 tggatttttc aaattctctc atcacttagc caatccctca tttcaaaaag ttagaacttt
    27841 ccaaattttt tgttatttac tatttcaata tcatactcca tcctagaaaa ttttgccact
    27901 tatttaggaa aaacgtaagt attaaaaaaa cacaaacaag cgttgagaac ttaattgtca
    27961 tgatagtcat tccatagatt cgctgcccaa tccattgcaa ttccacaaat gattcctagc
    28021 ataaaaccaa gcaaaaaacg tccgaatgca agtccaatca atacacctaa gatcattccc
    28081 agtcctgaaa attctccgtc atatttctcc atcttaataa gtcctcccat ttttgagctt
    28141 gacaactatg taaaacctcg ctatcattag tgtgttatta ttacgcagat gtgttggaat
    28201 tggcagacaa gcatgattga gggtcatgtg agcgttagct cgtgtgggtt cgagtcccat
    28261 catctgcact acaactcgtg aagttaattt tgcttcacga gtttttttgt ttgaacgttt
    28321 ctttatgcca ttatatacat atcactgtat cctttacaaa aagaacgtac aatcatgtaa
    28381 acagcctgag gtgagtatat gaaggtcgga aacaagctac tcgtagaaac ttgcaagtgt
    28441 taaaacaatt aatcgaaaaa cgagtaaaat ccctcaccta atactaaagc gagggatttt
    28501 ttgtatatta tctgtttatc accgttatta taaaggtaca aataccaagc acggttaatc
    28561 caaattgcat aaattcattt ttttgtacac tcatgctttt cattagctct ttaactgcca
    28621 ttagtactaa gatggcgata acaacataaa gtatatagta cgtccgcatt ccggaagccc
    28681 atactgtggg agaaaatccc ataattaacc ttgaacaaaa tcccattatc atcaaaataa
    28741 ctaaaaaaat agaagttttc ttattgtcaa aacttaaata aattccaaca attaaacata
    28801 gtaataatgc caagactact aaagtagcta tccaagtacc tggataaaaa agtgacagtt
    28861 tcgttcctaa ctctgtaaag agattattca ggttactact actccaaatc attgcccttt
    28921 tatttccatt gacgtaagta aagctttgac ccattgtatt accaaaataa ataatcaggt
    28981 ttaagaaaaa cggtaatgca gtcaatatac gcacataata gttttgacat ttcctatatg
    29041 ttagaaggaa aattaagaaa aatagcaata aaaataagat attcatgtct aaaa
//
LOCUS       DAFBSV010000028        29046 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.029, whole genome shotgun sequence.
ACCESSION   DAFBSV010000028 DAFBSV010000000
VERSION     DAFBSV010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29046
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.029"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(105..629)
                     /locus_tag="LLB18_001167"
     CDS             complement(105..629)
                     /locus_tag="LLB18_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5244180.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="LLB18_001168"
     CDS             complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="LLB18_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBK5244181.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1218..2198)
                     /gene="pta"
                     /locus_tag="LLB18_001169"
     CDS             complement(1218..2198)
                     /gene="pta"
                     /locus_tag="LLB18_001169"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HBK5244182.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2351..3031)
                     /locus_tag="LLB18_001170"
     CDS             complement(2351..3031)
                     /locus_tag="LLB18_001170"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBK5244183.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3157..4026
                     /locus_tag="LLB18_001171"
     CDS             3157..4026
                     /locus_tag="LLB18_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBK5244184.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4052..4567
                     /locus_tag="LLB18_001172"
     CDS             4052..4567
                     /locus_tag="LLB18_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244185.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4614..5207)
                     /locus_tag="LLB18_001173"
     CDS             complement(4614..5207)
                     /locus_tag="LLB18_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5244186.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5232..5411)
                     /locus_tag="LLB18_001174"
     CDS             complement(5232..5411)
                     /locus_tag="LLB18_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244187.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5488..5997)
                     /locus_tag="LLB18_001175"
     CDS             complement(5488..5997)
                     /locus_tag="LLB18_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244188.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6093..6473)
                     /locus_tag="LLB18_001176"
     CDS             complement(6093..6473)
                     /locus_tag="LLB18_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBK5244189.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            6803..7552
                     /locus_tag="LLB18_001177"
     CDS             6803..7552
                     /locus_tag="LLB18_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HBK5244190.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(7736..9013)
                     /locus_tag="LLB18_001178"
     CDS             complement(7736..9013)
                     /locus_tag="LLB18_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244191.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCHYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(9092..9736)
                     /gene="pcp"
                     /locus_tag="LLB18_001179"
     CDS             complement(9092..9736)
                     /gene="pcp"
                     /locus_tag="LLB18_001179"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBK5244192.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(9935..10879)
                     /locus_tag="LLB18_001180"
     CDS             complement(9935..10879)
                     /locus_tag="LLB18_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBK5244193.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KPGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(10881..11567)
                     /locus_tag="LLB18_001181"
     CDS             complement(10881..11567)
                     /locus_tag="LLB18_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBK5244194.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            12041..12361
                     /locus_tag="LLB18_001182"
     CDS             12041..12361
                     /locus_tag="LLB18_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBK5244195.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            12515..13420
                     /locus_tag="LLB18_001183"
     CDS             12515..13420
                     /locus_tag="LLB18_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK5244196.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            13417..14190
                     /locus_tag="LLB18_001184"
     CDS             13417..14190
                     /locus_tag="LLB18_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBK5244197.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(14371..15795)
                     /locus_tag="LLB18_001185"
     CDS             complement(14371..15795)
                     /locus_tag="LLB18_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK5244198.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPLQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            16006..16452
                     /gene="nrdI"
                     /locus_tag="LLB18_001186"
     CDS             16006..16452
                     /gene="nrdI"
                     /locus_tag="LLB18_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBK5244199.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(16517..18499)
                     /locus_tag="LLB18_001187"
     CDS             complement(16517..18499)
                     /locus_tag="LLB18_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK5244200.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(18513..19409)
                     /gene="murQ"
                     /locus_tag="LLB18_001188"
     CDS             complement(18513..19409)
                     /gene="murQ"
                     /locus_tag="LLB18_001188"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBK5244201.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(19412..20473)
                     /locus_tag="LLB18_001189"
     CDS             complement(19412..20473)
                     /locus_tag="LLB18_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBK5244202.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(20684..21250)
                     /locus_tag="LLB18_001190"
     CDS             complement(20684..21250)
                     /locus_tag="LLB18_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBK5244203.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(21278..22780)
                     /gene="eat(A)"
                     /locus_tag="LLB18_001191"
     CDS             complement(21278..22780)
                     /gene="eat(A)"
                     /locus_tag="LLB18_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBK5244204.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(23038..24159)
                     /locus_tag="LLB18_001192"
     CDS             complement(23038..24159)
                     /locus_tag="LLB18_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBK5244205.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            24285..25226
                     /locus_tag="LLB18_001193"
     CDS             24285..25226
                     /locus_tag="LLB18_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBK5244206.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(25376..26272)
                     /locus_tag="LLB18_001194"
     CDS             complement(25376..26272)
                     /locus_tag="LLB18_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBK5244207.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            26541..27881
                     /locus_tag="LLB18_001195"
     CDS             26541..27881
                     /locus_tag="LLB18_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK5244208.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            28099..28542
                     /locus_tag="LLB18_001196"
     CDS             28099..28542
                     /locus_tag="LLB18_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBK5244209.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
BASE COUNT         8366 a         6012 c         5221 g         9447 t
ORIGIN      
        1 tattcaaaaa aaatggactg cgacacgact tttgtcacag tcccttcgtg tgtttttctg
       61 ccttctcaaa aggatgacag tttctcactc ttttcctatt tcttctattc aatcaaataa
      121 ctcattttat atacatctaa aaattcacct agatctgttc ttgcccctct aggcatgacc
      181 gcttcgattt ggaagcccat ttttcggtaa aggtgtacgg ctctttcatt acgaacttga
      241 acgtcaagct ccaatcgaaa aagtacaccc atttccttcg cccaactgat gatttcttct
      301 agcataagag tgcctagtcc cattccccaa tattcctgca gaatactgat accgacttct
      361 cccacgtgag acaaacgaaa ttgactgtct gccttgacag atgctgttcc aataatcgtc
      421 ccttcataga ttgcaagcag caataaatta ttattgcttt cgtatatata atccaactct
      481 tcttctaagg tttctggtgg taacaggagt tctgcttcat ccaaaactaa aaattctgtc
      541 tccttattaa cttgtcccat catcaaaaga atgtcttttg catctcctgg cactgcttcc
      601 cgcaagatga tcccaacttc ttcactcatg attttcagcc catttttcta gaattcgctg
      661 tttgaaggtt tcactttgct ccccgtatga gattagtttc acataccgct tttctaaatc
      721 tgtatcactt ttttctaaaa tcagttccaa ataatcctcc ggcagtgctt cttctaatag
      781 atttccccat tcaacaacgg aaagcccatc accttcaaaa tattcatcta accctaaatc
      841 tgctccgcta gctgctaccc gataaatatc catatgatac aacggaatcc gaccttgact
      901 atattctcta ataatcgtgt atgtcggact tttgatcatt tgcgttatcc ctaatccttg
      961 ggcaattcct ttcgtcaacg ttgttttacc cgcacctaga tcaccagtca atatcagatt
     1021 gtcacctggc attgcggaat gaccaattgc ctctgcgaat tgttctgtca ttgttaatcc
     1081 tgatagttcg atcatttttc atcttctccc gctcttcttt ctttttgcca gtatatcgcg
     1141 taatgaagtt tttttaaaga aaaaatgaac tagtcaagaa cagcagctgc tgtttttggc
     1201 tagttcgcgt gtatttgtta atcaatcaat gtttgtgctg ctgtgataat cgataattta
     1261 tatacatctt cttcatttgc tccacgagac aaatcagaaa ccggtttgtt caagccttgt
     1321 agaattggtc cgattgcttc aaagttaccg aaacgctgag caattttata gccgatattt
     1381 cctgactgca attctggaaa tacaaagact gttgcttgac cagctacttc tgaatctggc
     1441 gctttcagtt gtgcaactga aggaacataa gaagcatcaa attgcaattc gccgtcgatc
     1501 atgtattgtg gcgctagttt tttagcgatt ttagttgctt caactacttt gtctacttct
     1561 ggcgatttcg ctgagccttt tgtcgagaag ctcatcattg ctacttttgg ttcgatatcg
     1621 aacaattctg ctgtttttgc agaatctacg gcgatttcag ccaattcttg cgcagttgga
     1681 ttcacgttga tcgcacaatc cgaaaagaca tatttttctt gatctcttcc acgtaccatg
     1741 atcatcgctc cgcttgtccg actgatgcca ggctttgttt tgatgatctg aagtgctggg
     1801 cgaacagtgt cgccagtcga atggatcgct ccagagacca ttccgtctgc aatccccata
     1861 tacgtaagca tcgtaccaaa gtaattcaca tcttttaaaa tcttttctgc ttgttctttg
     1921 gatgcctttc catttctacg ttcaacaaaa gtatccacca tttcatccca cttatcgtaa
     1981 ttatcagggc tgatgatcgt aaagctagat gttttgattc ctctggcatg cgctgcattt
     2041 cttatttctt cttcgttccc tactaaaatg ggttccacaa gttcttctgc tttcaaccgg
     2101 gcagctgcgc ctaaaatacg agcatcagta gcttccggga aaacgatttt gatcccacgg
     2161 cgaacaattt taaatcttaa actatcaaac aattccacaa gatgacctcc agacgttttt
     2221 atatgtatta tcatacacta ttccagaaaa aaagaacagt ttattttatc tgtatcagtc
     2281 aaaaatgctg gaaaaattaa gtttttcaca tacaaagcga actgcactat aacaggaaag
     2341 cgctgtttta ttacactgtt tcaggcagtt gccaatcaat cggttcttct cctaacgcaa
     2401 ggagcgcatc attcgttttc gagaagggtt tggaaccaaa aaagccacga cttgcagata
     2461 acggactggg atgtggagat gttatgatga tatggcgact cttatcgatc attttgattt
     2521 tttcttgtgc cggttttccc cacaagataa acacgattgg tttttcccgt tcatttaatt
     2581 tttcaatgat cgtgtctgtt aatctttccc aacctttccc gcgatgagaa tacgcttgcc
     2641 cttcccgaac ggtaagaacg gtgttgagta aaaggactcc ctgtttagcc catgacacta
     2701 gatttccatg ttgaacaggt gcgattccaa gatcatcata aagctcttta tagatatttc
     2761 ttaacgatgg cgggatcttt acgccaggtt gcacagaaaa agataagcca tgagcttgat
     2821 tttctccatg ataaggatct tgtcctaaaa tcaccacttt aacttcttca taaggagtca
     2881 attccaatgc ttcatagata tgatacatat ctggatggat cttttgggac gcatattctt
     2941 tttttaaaaa ttctcttaga tgcagataat aatcttttga aaattctgag gacaaaactt
     3001 cttgccaact gttatgaatg atttctttca aaaactccac ctcctaataa aaagaataac
     3061 tcacattttc ttcaatcaca agggacaatc ttcaccctca gcacttgatt aatatggtaa
     3121 actaggaaca agaagcagaa aggaacgata atcattatga tcaaattaat tgcatcagat
     3181 atggacggca cattattaga tgcccatatg agtgtttctc ctgaaaatgc cgaggcgata
     3241 cgttttgcaa atgatgccgg tgttgagttc atggtcgcta ctggtcgaaa ctatcaagaa
     3301 gctcgcgcag ctttagatga ggtaggaatc gattgtgcga tgatcacttt gaacggggca
     3361 caggtatttg ataaagaagg aaattcattg tttaccgtgt cgattccaaa taatcaagca
     3421 atctctgttt tagatattct agatgctaac ggtatttact atgaagtagc aaccaacgat
     3481 ggtctttatt ctgaaaatca agcgaaacga attgaaagtt ttgcttccat ggtggctacc
     3541 catttacctc accttacgta taaaatggcg attgccatgg cctcagctaa gctggagtta
     3601 ttgcacatca catacgtgga cagtattcgt gctattttgg aagaaaagaa tctggaagtt
     3661 ttaaaaatta tttgttttca tacagaaggg ccagctgtat taggtccagt tggaaagcag
     3721 atttctcttt taggcgatct agccgttact tcctctggtc aaaacaatat cgaagtgaac
     3781 cataaaaacg ctcaaaaagg aattgctgtt gcccatgtcg ctcacgagcg tgggatttct
     3841 ttagaagaag tcatgacgat tggcgataac ttcaatgatg tcagcatgct gcaagtagca
     3901 ggagtcagtt tcgcaatggg aaatgcagaa atcgaagtaa aagattatgc caaatataca
     3961 acggacacaa accttgaatc tggcgtagga aaagccatat tgcgcgcgat tgcagaagac
     4021 ttgtagtttt atctagaaaa gagggatata gatgtcagaa tttttcattc aggaaaagca
     4081 gcttggacgt gcaactcgga caattgtcaa aaacgaaaaa ggacattccc tgtttttgat
     4141 ggttggtcgc tggggaacaa agggcgatgc attgtctctt tatgccatga atggcgatct
     4201 cgttgctcac atcaagcaga taagcctgac attcggtacg cgttttgagc tgtataaaga
     4261 gttcgaaaag gtgggaacca tgcagaaaat attcaattgg cccggtgact tttattatat
     4321 tcgtagactt cactggacag tccaaggtga tatctataat catcaatatc aaatccatca
     4381 tttcaatcag caaatcatga aaatggataa agcaacactt ttttcaggag attactatgt
     4441 attggatgtc tcaaatgatg aagatgctcc agtttgtatt tgtattgctg cggttttaga
     4501 ttactggctc taccgtaaag acaaaagtcg cgataagcct gtttcttacc gacttaactt
     4561 aagttaaaaa gatgtacctg aaatgcggaa atacgcattt caggtacatc tttttagata
     4621 ttcttttgca tatgatcata aagatgacca ctgatcatcc gctgaccgac aactttgaag
     4681 tcatggcgtt cgtataattt tttagccttt ggattttttt catccacact tagaccgatg
     4741 acggagcgat tagctttctt cgccaattta ggtaatgctt ctaataatcg cgaaccgatg
     4801 ccttgtcctc taaaatcttc tgatacactg atagagtcca aataccattc gttgggaaac
     4861 gtttctttat caatgaacaa acgtgtagac gcatctagct gatatttctc taagataggt
     4921 accagtggct gatcgatgat tgattcttct tcatctgtat aaccgtaagc aactcctgca
     4981 actttaccgt ctatttcttc tacgatacct cgtgaataac tgtaacgata atttggatca
     5041 gtgattgctt cttctaaaat ctctaaagtc ttttgttccc ctgtctgctt caaaaatggc
     5101 agttccatat cttttagaat cactaagatc aatggggcga tttctggagc atcttctttt
     5161 ctcgcaaaac gaatcatagt ttcctctcct tttctccatt ctaacatgca gaaaaagaaa
     5221 tcgcaaaatc gttattttaa aaaatcttca atcttttcag taatgaaata accatgagta
     5281 acgattcttg ccgcttcagt tcggcaataa gggcagacga ctggcatttc tttatcatta
     5341 tgttcgacta cattattgac ttcttcgtat gcaaattttt ttccgcaatt agggcatttc
     5401 attttttcca tgttatctca acttcctttc atctttactc tcttagctta ctcttatatt
     5461 gtaaaaaaga gaagcaatat ccttcttcta tgcagatatc catacctgac ggtcctgttc
     5521 tccatctatt aatcggactt tataataagg acgttcatct ttgactagaa gtgtccactc
     5581 tttcactttt gcttttttcc cgtagtagct gactgcttcc ttcatcgctg cttgcggttg
     5641 tttgaactct tccgtttttt ctatatcaaa aagatgttct gcggcctttt ccgtgtcatt
     5701 tcgtacggtt gttttcccag tggatggatt gactgctatg acttgtcctt cacaaaaaaa
     5761 ctggtattca tatgttgcat tcgtaggatt ctccaaatct ttttcaactg caaaatgaat
     5821 agcagatatg ttatgttctt ttgtttcgtt ttttacgatt gctgctgctt ttttcaatga
     5881 gatccgatat tcctggtcac taatatcatc catgtgaaaa gcggcattga gcagtcccgt
     5941 cataccggta atccctatta cgatgagggc agcaacacca aacatcattt ttttcattct
     6001 tcattctcct gtttcttttt tttaaagaat atcaagaaat gaacgaatga aaaatcgaat
     6061 gaaacgaaaa aaaagtgaca attttgttat ctttattcgt gcagttctaa tggcaatccg
     6121 tctggatcaa agaaaaacgt catttttttt cctgtaaagg tatcttctct aatcggttct
     6181 gattcgatcc ctaaggactg caattctgca attgtttctt caatatcgtc tactttgaaa
     6241 gcaagatgac gcaagccaca agcttctgga tagtttggtc gttgtggcgc attagcaatt
     6301 ccaaaaatct ccaattcagc acttcctagt ttcagatcta atttatagtc atctcgttct
     6361 ttgcggtaat tttctctgat tacttcaaat cctaatttat taacataaaa atcacgtgat
     6421 ttctgataat ctgaaacaat gatggctata tgatggatcg ttgtaaggtt catatgagca
     6481 ctcctattct tcgtttaagc tcggatctat attaatctcc agttccattg taaatgtgtc
     6541 agattgaaaa aaatagctgt ttttcctttt tataagaaaa aaggcaaaaa aaacagaaag
     6601 taggtcctcc aagacactct tcctgttccc aatataataa atgaaagtaa gaaattatat
     6661 tttcaagaaa acaaacagaa aattatcata acacaaatta tttataattg aaagactagt
     6721 tttttttcaa gaaaagcata caatagattg tgttagtaaa tacagaacac actacattta
     6781 gtgtcttaag gagtcctcat acatgaagtc atattttcag tttttagctc atcagctaaa
     6841 aggctggccg caacaaaatt attatctttt ctttttcagt cttggctgcc aggtcatgac
     6901 tcttgtcaat agtcccatca cttggctgtc cgttattaca tttatcggta ccacgcttgg
     6961 tgtattgtgt attttatcca tcaatgcggc aaaatcagtc aacggtattt taggtatttt
     7021 gtctgcgatt tgttttatta tcgttgggtt ttcagcaaag aactatttaa gtatcggtga
     7081 acagattgct tatatgatca cattggatat ccccgtattg ttaagtaaag aatggaatca
     7141 taatatggct tcaaaaatcc gaaaattcac tggaaaaagc tggtttatcg caatcatcag
     7201 tactttcctt gtctatcttg tttcaggatt cctgattggt cgttatacag atgatcctcg
     7261 gccgtgggta gatgccattg ctttttctat tagcttgact gctggtatca tcagtttctt
     7321 gcgttacaac aaccaatatt actggtggtt agcttcaggg cttgctcaaa tggtcctttg
     7381 gtatatttca tttacgcatg gatctgcaag tttggcgatg ttcgtgaaca gctctgttta
     7441 cttgctgaat gatgtccttg catttaccgt ttcaccttgg tataaccaaa aagaacgtga
     7501 acgtatgcaa aaaatggaag aagaatacta caacgcacaa caacacgcat aaaaaaactg
     7561 agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg
     7621 aatcagaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt
     7681 cgtgaatttc ttcttatttc ttggagttaa acgcttctgt cccagcctct attttttata
     7741 gtaattcctt cagatacttt cttgcctcat cattgaaacg cagtgattct tctaacttct
     7801 gataatattc caacgcttgt ttctgagctt cagtaaaacg ataatgtttt cctttccatt
     7861 tgtcgattgt ctcttgcaca tttccagatt ggatatcttt cactactagt tgccattttt
     7921 cttttgagac tgtacggtct ttcttatcag cagattgtat agcttctcgt tctttacgca
     7981 atacttttaa aaaaccattt ctgactatcc gaggaatgct gtcgaagaac ccttctgtaa
     8041 aaccatagtg acaatattgc ttccaaataa atagatagat ttttggttgg atgaatcgtt
     8101 ggtttttcgc aaaatattcc atctgagcag tgacttctgg tgttcgttga cgttttgtct
     8161 ttctcaacac ggaaataaat gtttcaaaat aagcattagg atgtactggc acttcttcat
     8221 atacgatgga ttgccaatct ttacgtaaaa atgcgcgata gttgatcaag aattcttcta
     8281 catcctttac taattcttct gcaaagtcgt caaatagttc tttttttatc tgtcgctttt
     8341 ttgactgccc attgatgtgt tcacttattt tcttgatttc attttccaat gcttgataat
     8401 ccgctatgta aatcggcatt tctacttggc gaaattctgc gagccgctga gctaatttta
     8461 tatccggtaa atatggctgt ttcatccgac gattttggta caagacaaaa cagtattttt
     8521 gccatagtcc ttcaggaaaa tcgatattct tctgcttaag ccataataat tcgtctaagg
     8581 ccagatcaac ttttgtcatt ccctgatgga tcgaagctgc cactgtcgga gagacatgca
     8641 ggtgatcggc aaagtggttg atgcctagtt ttaggatctt tccggttttt ggcgatttaa
     8701 cgatgtattg cacttttaat tctctaccac actcacaata caatttttgc tggcttcgtt
     8761 ttgttcgaaa aaacggattg atcttgaagt cagaaaacac ccaatctgtt gcagctaaat
     8821 aatgttcttc cataaaacga gagctgatta gatatcggcg gtgcttatcg actagttccc
     8881 gctgtttttt cgttaatttt gcatagatct cccaacgttg actgcttgtg tattgtttag
     8941 aaattttgat gggatagctt ttgctgattt cttttggaaa ccattcttca aagacggatt
     9001 gccattcttc cacggctgtt tctttccttt ctaattacaa aaagctggct actaacataa
     9061 cgttagcaac cagccagtgt ttcttgctaa attagtgagt tgttccggca tttccggaaa
     9121 tatcttcttt attttctact gctgcttcaa ctgcataagt caaagaagaa gcaatgtctt
     9181 ctaaagacat agaaggcgta cccactggac gatcgatcac ttgatcgggt gagaatggca
     9241 cgtggatgaa cccacctcga attgccggga attgtgtttc gatcaaatga agcaaacgat
     9301 acatgatatc attgcagaca aatgttcctg ctgtataaga gatgtacgct ggtagaccat
     9361 gatcttgtac attttttgtc attgctttga ttggcaatga ggtaaagtaa gcggctggac
     9421 cgttttcttc taaagccgta tcgaatggct gatttccttc attatcaggg attcttgctt
     9481 ctgctagatt gattgcgaca cgttcgaacg agactgctga ccgcccacct gcttgtccga
     9541 cacagatcac gacatctggt tggtgctgtt ggatggcttc tttgactact tgactgcttt
     9601 tttcgaatac ggtcggtact tccactttga tgatttcagc accgctgatt tcatctggca
     9661 ttttttttac tgcttcatag gctggattca ctttgtcccc accaaatgga tcaaaacctg
     9721 ttactagtac tttcatctgt tgttcctccg tccgattgat ttaacatatg gttatctttt
     9781 atcataccat tttccttgaa cagcgtaaat aaaggaaaca atagtttaaa taacataaca
     9841 gatcaaactt aatatattct tataaaaaaa tagtgttcca ctacaatgtt agaagaggtt
     9901 gcgacaatta ttctgtcaca acccctctct tctattattt aaatagaatc atataagcaa
     9961 tttggaaaac tagcataaat aacgcaataa acaactggtt tttgatcact ccgtatttgt
    10021 ctttcatctc cagcatcgct acaggcacga tattgaagtt agcagccatc ggtgtcagca
    10081 gggtcccaca aaaaccgcaa gtcaatgcaa ccattcctat taacgctgga ttcgctccat
    10141 gactaaatac gaatggtgca ccgatcccaa ccgtcatcac ggtgatggcc gcaaatgcat
    10201 tccccatgat taccgtaaat atcaccatgc caagagcgta aatgatgatg ccgatgttca
    10261 catttccttc tggaacgatc gtacctactg cattggaaat cactgtccca actccagcgc
    10321 ttgtaaatac cgcacctaga gaagctaaaa gcattggcaa catgcttaac ggccctactg
    10381 tgcccagcat atctgctgca tcatctaaaa atgtacttgg tcgattatct cgagaaaaga
    10441 acatcaagat tagcatggct gcaaaaacac cgacgcccac gccgactaaa gcacctaaat
    10501 tggtaaatag agcaaacaag atcgcaaaga caccgatact caaagctgga ataaaaattt
    10561 tcattcctgg tttgtctgac attttttcca tatattcttt tgatggaagc cggctttctc
    10621 ctttgctgac tttcttagca attgctggta tggtcatcgc aaagatcaag ccaccgttca
    10681 cgattgccgg aagccatctt cctcctgcaa taactacccc taagaccgtc cagaaaaagg
    10741 ctgacccata acgatgagga ttggttttat ctgttaaatt tcttactcca gtgtaaatca
    10801 atacgagtcc catcacgata taaaggatct ccagtaattt atcgcctaat aaaatatcag
    10861 gatttgtaaa aaagtccatc ttattgcccc tttcctggat aatatttctt cgctaatttc
    10921 ttttctttaa gatagaagta gacacttgcc acaactaaag ccgtgatagc cactggaact
    10981 tccactaaag caagctgtcc caatgttacg tcatatccta gatctttcag tgttgattgg
    11041 actagcaacg cccctgctcc tccgatgaat agtacttggc caaagaacca gcagacattt
    11101 tccatagctg aagccatacc ttttagttct tcttcatgct taggatggac ttctaaccct
    11161 tttgattcga tggtccccaa tgccatcggt aaaatgattg gacgaacaaa tccagcaact
    11221 ccaccaaaac tcacgttaaa agccgcaaag atcattcgaa agatcccata aatatctaca
    11281 atcataccag cagatacttt cttgaatcgc ttgatcaagg aagccgctga ttctttcaga
    11341 ccatttcttt caagcgttcc tgttgccaac ataatgatga taaaaatcgc catcccgcga
    11401 ttgtttacaa aacttgtacc taaaagttct aacattcctt gaatgccaag accgccagtc
    11461 aaagctgtaa caactaaagc aaccattacg atcaatatcg agtctaattt aaatgcaaac
    11521 ccgagaataa caatcaagac gcctaaaagg ctaagataat tttccatata ttttcctcca
    11581 taaaatgaca atattttttt aattataaag caaaacacat aaaaaatata gttgttttct
    11641 cacgaaatag acactatttt taaatatttt tcgttatttt tttatcacaa aaattatctt
    11701 acttattgta aggtaaagct ttttttaatt tattgcccga taatatatag aaataaggtc
    11761 tagttactgt tttttttaaa tgattaataa ataacaactt ctttctatga aattgcaaag
    11821 cattcatctt cttttccgct aacgatatat ccgtcagtgc ttggtacact ttactaaaaa
    11881 gtatgagatt gccgatatct ggataggtgt gctatactac agaaaaagat atacaatctg
    11941 ccaccgggta ggataaagag gatgatcatt ccattaggtc tttgaaggga tgattttcct
    12001 ctttttgtgt atttttttat agttaaggag gaatgtaagt atggcatgga tggaattaat
    12061 catagcagga attttggaag tattctggtc aacgatgatg aaatggagtg atggtttttc
    12121 taaaatcaat tattcttttt acacagtgat tggcatgatt gctagttttt actttttgtc
    12181 aaaggcaatc aaaagtttgc cgatgagtct ctcttatcct atctggacag ggattggcgc
    12241 agttggttcg gtcataattg gtgtggtctt gtttcatgat aagctgaatc tttccacttg
    12301 gttctttgtg gggatgctac tcatcagtat cattggcatc aagattacta gcggccacta
    12361 gacacttgga ataagtactg atcagaaaaa ataagccttt ttatttaata ttcaattttt
    12421 ttatgaaaaa ataagaaata agtccaatga cctagcgact tctccactca tcaggtgtat
    12481 gcttgtacta tctatagaaa aggagtgaat atttttgaaa agtctttcgg tccaagaatt
    12541 atccaagaac tttggtcaca aacaagccct cagcgatgtc agttttagct tatcccctgg
    12601 caaaatcgtt ggattagtag gtcctaatgg cgctggaaaa acaacgatca tgaaagctat
    12661 tttaggactg atccattact cagatggaac aatctgtatt ggtgaaaatg agatttctcc
    12721 ctctagtcat aaagggttgg aacaagtagg agcattgatc gaatacccgg gtatctatcc
    12781 attcttaaca ggctatgatc atctgaagtt attctctgaa accaacgatg tatctgctat
    12841 cgacactatc gtgaatcagc tcaagatgga aaagtacatt cacaaaaaag cgaaatccta
    12901 ctcgttggga atgaaacaaa aattgggaat tgctcttgcc ttactgaacc atccgtctat
    12961 cgttatttta gatgagccga tgaacggttt ggatccacaa gcaacaagag atgtgcgaaa
    13021 aatcattacc gacttggcta ctcagggcac ctctttcttg atctccagtc acttactcag
    13081 cgagcttgaa aaaatggtcg atgagctgat cctgatcaat caaggaaaga tcatcaaaca
    13141 atgtacaatg gctgaattga accaaacagc gcaagatttc atcgttatct ctacaacaaa
    13201 tgatctagct gctcgaacga tcttgacaga agctggatat actttggaag atcctgataa
    13261 aatcaagctt ttaaaagaaa acgaagaatt attaggaacc gtgatccagc tattgtctgc
    13321 acaaaatatc catgtgacag acgtccagca tctgacgaat gatttggaat cttctctatt
    13381 ggaaattctg gattcagtaa agggggaaga agaaaaatga cattgcttgt aaaacaagaa
    13441 ttatttaaat tgatcaagaa aaagtcaact gctgttttat ctgttctatt agttgttttg
    13501 ctcataggaa cagcacttct agccaaaaaa tacacgacga tcattgatcc agttgaaatg
    13561 actgctcagc tttttagtgc cacatcttgg attgtcttta tcatgattgc agctgcaagc
    13621 acgatcattt cgatggaagc acaatatggt acattgaaaa atctccttta tcgaaagtat
    13681 tctcgaggag aaatattagt aagcaaatgg atcacattag ttatttattc tgtttattta
    13741 taccttttag ctattattgt cactgtgttg atgaaactga ttcttttccc ttcgatttcc
    13801 ttcacggaga aggtttctac tggtcaaaca ctgatccaaa gcttgttcac ttatactttg
    13861 ggtagttata tcggtttatg gctgatttta agtttagtgt tgatgattgc ttgctttatc
    13921 aatagttccg gcgcatccat ctcagcagga atcgtctttt attttgcttc gtcaatcata
    13981 tctggtatcc ttattgcact catccaaaaa tgggagtgga tcaaatggaa tccgatcagt
    14041 atgttgaatc tgcaaaacca aattggaaac gaagagatca tgaagcaatt gactcatctt
    14101 tctactaatc aaatgctatt cggtaattta gcttacatcg ttttgttctt agcattagga
    14161 tatctcgtat ttaagcgaaa aaatgtatga tgactcatca aaaaagaggc tgtgaaagag
    14221 acgttcagcc ttattgccga ttggctgtct cttaaacacc gtttattctg aaaaaggagc
    14281 tgtgacaaca tttgtgtcac agctcatttc ctagtatgtt tttgaataaa cgacaggctc
    14341 acaacctctc tttatacttc ttttatactt ctatacgtga agcatcccag tggcaaataa
    14401 aaccattgca atcactccga ccatcgtcac acctataagt aaaatcttat ctaagtggat
    14461 atgttgtaaa ggctcgtttt gctccttacg tgctttgagg taaaaataaa tgcctggcaa
    14521 gaaaagaaca agaacaagca ttacttcatt aaaggctacg actagcatag cccatacttg
    14581 aaaggcactt gctaaaagcc ctactaaaaa ttggacccat tctttccgct gataagaaag
    14641 tttcatttgg tacaatccta agaaaagcca cgtgaagaaa atagctgctg taccaagtgt
    14701 gtaagcaaag ttataagcac tgtcagtgaa taataatgaa agtaaaaaga cattcgtaca
    14761 taacgtcgtc aatacgatag cataagttgg tgccccattt ttgttgagtt ttccccatgc
    14821 tttaggcaaa agtccgtctt cagccatgtt tcccattgtt tcaatcggta agatcgtcca
    14881 tgagagccaa acaccaacta aagaaatgat caaaccgccg ttgatcacga ctgctcccca
    14941 tttaccaacc atcatttcaa acacatagcc catagcaggc tgcgccttga tcgtttgcag
    15001 ctgattcatc gtcattgtcc catatggaag catggaaacc aagacgtaaa taataatcaa
    15061 gccgaatatc cctagaatcg ttgctttccc aacatctgat tgtttttttg ctcgtgaacc
    15121 tacgacagag gctccttcaa taccaacaaa tacccaaagc atcaccatga tgcaactcaa
    15181 tacttgactg gaaaacggga tcggctgtcc attcgcattc aatataatgt cgctagaaaa
    15241 gttatcaatg aattgttgga tcgaaaacgt gctgatagct actacaataa ataaaaataa
    15301 tggcactaat ttacagaatg tgacgatagc attgacgaaa ctagcatttt cgactccccg
    15361 attcactagc catgcatatc cccataaaaa gactgtactc atcacgatcg atgccagatt
    15421 ttgcccacct tcaaatactg ggaagaaata tcctaatgcg ctcatcaaca atgttgcaaa
    15481 agctacgttg cctaaccagc atgtgagcca gtaaccccaa ccgctgataa aaccagcgaa
    15541 acggccaaaa ccttcttctg cgtaactaaa gatcccgcct tttaaatctg gacgtttttt
    15601 attgatatta ttgatcgaca aggagagcat caacattgct gttcctacga gtacccaact
    15661 gaaaatagct gggccgccag ccgatccgga gatgtccgtc ataataccaa atacgccacc
    15721 tccaatcgct gaaccaatta ctaaggcagc aagtggaatt aaaccaattc cttttttctg
    15781 ttgctctgta tccatgtaag catcctccaa aataaaaccg cttttatcaa aaagtataac
    15841 aaaccttttt tatttttact taattaataa aaactttaat agaaatataa ttctaccggc
    15901 ttttttctca ttatacaagc aaagcgccta gtccctttcc aaattacacc accaaaaaac
    15961 ttaaaaaaga tgctatacta aaaggaaaga attggaggat gatccatgaa cattttatat
    16021 atatcgattt caggaaatac gcgtgccttt gccaaacatc tagcagaata tgctgaaaaa
    16081 atgcatgcag aagatcctgt caatcctgaa gttactttaa aagaaatcca tgaaaatagt
    16141 gattttacga aagaaacaga accatttttt actttcgttc ctacttattt agacggcgga
    16201 aatggtttag ataacggtga tacagaaatc ttgaccgaaa cgatgcgtga atatctggaa
    16261 catgaagaca atcataaact ttgtcttggt gtagtcggta gcggaaataa aaacttcaat
    16321 aatcagtatt gtctaacagc caaacaatat gcacaaacat ttggctttcc tttcttggca
    16381 gattatgaat tacggggaac accatctgat gtgacacgaa tttatcagat tttagcagaa
    16441 aacaataaat aataaaaaag aagaagctga aaaatagatt tcagtttctt ctttcgtttc
    16501 tattgtttct atcatattaa gctttgacat ccatcacagg tgcttttgct tttgctttac
    16561 ctgttttttc caagacaaag ttttttacac gatccatatt ggttaccaag acgatcatgg
    16621 atgtttcttt gcctgctgct ttgatcgctt ctaagtcagc ttctgctaca agcgtatcag
    16681 gtgtcacttg ctgcccttct gttactttca catcaaatgg cgtaccgcct aagtcaactg
    16741 tgttgattcc catatgaagc aagatttcta aaccatttgg cgttgtgatc ccaatagcgt
    16801 gtttcgttgg gaagacagag ctgactaccc cagtaactgg agaatagata tgtccgtttt
    16861 ctggttctac aaagtagcct tcacccatca tcttttgtgc aaaaactgga tcacttgctt
    16921 tatctaaaga aacaactgtt ccgtcagcaa ctgatgagag gatagtcaca ctttcagctg
    16981 aagtttgagg tactactttt tcaggcactt catttactgt ggctgtttca gtcgctaatt
    17041 cttctttttc taaacggtct ttaggaatac cgaagaagaa tgtagcaacg aagccaccag
    17101 cataagctgc caataatcca aggatgtagc ctaaccattt accgtcagag atcaatggga
    17161 tcaaagcggc tcctgaaggt ccaatagcga tagccccgac atttccgatc attccgatca
    17221 ctgccccgcc gatacctcca ccgatacaag cagtaataaa tgggcgtcct agaggtaatg
    17281 ttactccgta aatcaatggt tcgccgattc ctaggatccc gactggtaaa gctcctttga
    17341 tcatttctgt taattcttta tcttttttgc agcgaatcca taatgccaat gctgcaccca
    17401 cttgtcctgc accagccatc gcaagaattg gaagcaatag cgtacgacca gtttcatcaa
    17461 tcatttgcac atggattgga gtcaaaattt gatgcagtcc gaacataacc atcggcaaga
    17521 ataatgtgcc tagaacgaag ccggcaaatg ctccaccaac gccaagtacc cagttgatcc
    17581 caccgaccat gccatcagaa atgaaacctg ctaaaggcat gatgaagaaa atttcaatca
    17641 gaccgatggc aatcaacgaa agagttggtg taacgatgat atctaccgca tcaggtacta
    17701 ctttatgcag ttttttctca acgattgaca atagccaaac agcgaagatg acacctagga
    17761 tcccaccttg tccagctgca agagcttcac cagtaaataa gtttttcagt ggtgcttccg
    17821 gattcatccc tgtcagcatc acaacggccc cgataactcc accaagagtt ggtgttgcac
    17881 caaaaacttg tgcagcattg atacctgtat agataactag gtagctaaac atcccgtttt
    17941 tcaagatgtt catcacatcg atatattgtt gccatgttgc tgcatcaagt gttccggctg
    18001 tgactaagtt tgctaaaact gcggcaatcc ctgccacgat cccagtaccg acaaatgcag
    18061 gaatcattgg cacaaagata ttagaaatgt cttttaatac cgatttgatt ttagatggtt
    18121 tttgtttcga tttttgtgcc gctttcattt cttgtgcccg ttcgtttaca cggtcttttc
    18181 cagatgctga tgaatttgct gtagctgtac ttacagaaga aagtttttct cctaatttca
    18241 cgcctgccaa atcaaccatt tgctgtgcta ctttgttcac tttcccaggt ccgatgatga
    18301 cttgaagctg ttcatcttct actacaccaa gcactcctgg aatcgctttt aattcagaga
    18361 catttacaag atcatcattg atgatcttca tacgcacacg agtcatgcag tggacaatgc
    18421 tttctacatt gcccatgccg cctgcccctt tataaatttg ttttgccagt tcttccaaag
    18481 tcagttcgtt ttttgccatg gtcttttccc cctcataagg tcccttttac aaatccgttt
    18541 gcttcagcta attttgcttg agcttcctct ttatcactat ttgtcaaaat catgacgata
    18601 gccagcttaa cattttgatc tgcttcttca aagtactttt cagctgtttc gtaatcagct
    18661 tctgtcgctt gcatgatgat tcgttttgag cgttcgatta gtttttcatt tgttggtttg
    18721 acatcgacca tcaagttatt gaatacttta cctataccaa tcatactgat agtagaaatc
    18781 atattcaaga taagtttttg tgctgttcct gacttcaatc gagtagagcc tgtcaaaaat
    18841 tctggacctg catcgacttc gattgggaaa tccgcgtgtt tactgatttc ggcttgttta
    18901 ttgcaagaaa tcgttcctgt gacagcaccg atcgattttg cgtaatctaa tccaccgatc
    18961 acatatggtg tacgaccgct agctgcgata ccaataacta tatcattttt tgtcaaattc
    19021 agcttgatta gatcttcttg ccctagctca taagaatctt cggccccttc gacagctaca
    19081 gtcattgctt cttctccacc agcaattaga cctatgacca tttccggttc tacaccgaat
    19141 gtcggtacgc attcagcagc atctaacaca cctagtcttc cacttgttcc ggctcccata
    19201 taaatcagac gtccaccttt tttaaaggac tcaatcgtgt tagcaatcac tggttcgata
    19261 cttgtcagtt ctttttcaac cgcagcggcc actttctgat cttctttgtt cattagttga
    19321 acggcttgag aaatactcat ctcatctaat ccaaaagttt cttggtttct gcgttccgtt
    19381 gttaggttct ctaaattgat tttgctcatt tttatcttcc ttcttttctt ataaattgat
    19441 agttcatacc agctttgatt tggttgatca atggtagctc ttctttgata actttagcta
    19501 ctacattcac tttttcatcc gctggcaaat catatttggt taattggatc tcacccatat
    19561 agcgcaaata cttttcgtta tctaaagtaa tagacccttt catacgcgta gctgtatttc
    19621 ttgctgggat aggcggaatc tctcgaaaac gtgcatctac gcttcgtatg acatctcttg
    19681 catcgtcttg ccgattcgta tgcttcccta atatatattc gtaaaattct tcatctacag
    19741 gttccgtatg gagcaagact gtctgttctt tttggaaaga agcaaattgc tcctgaacgt
    19801 tttctgacag acctgcatct ccgatgtaaa caatatccgt gttacttgct aatagatcta
    19861 gagcgcctgc aagaggatgg atccctcgat gttcttccaa agttggcaat ccttgatata
    19921 gtgggcctct caactctgta tctcctggta caaaaccttg gacaaggaga ccttgaattt
    19981 tgagccattg attttttttc tgataccatt ctttgtccag ccctgtttcg ggacgtggat
    20041 aataattatg ccaagcttca atctgtgaga aatcagcttc tgcttctttc aattcatcga
    20101 tatctttagg cgtgatcgtg ctagcattca aactgatttt caattgatgt gaccagtcgg
    20161 caatctgctg attggaaata tgataatcca ttcttaaacc tgttacacca attgctttca
    20221 aaggcgttag atcttctaat gaaaaacccg ctcgttccaa tgcctctcct gaaatatcga
    20281 ccatcaattc tagtttattc tttttcgctt cgcttcctag ttcgatcaat cgcttttgat
    20341 atgccgaaac atcatcttct ggtatatgca tggaagtgaa aataccgaca aagccattgg
    20401 atgccatttg gcggatatac tgtttcttct cttctgacaa agaatcgttc ataaatattg
    20461 aaaagccaaa catattatcc ctctttttct gtatccgtct tcatttctat gactagagta
    20521 tatatctaaa gaaacaaaat ttcaatactt ttattaaaat aattaaattt catttctaaa
    20581 ggttgagttt atattatcaa aagaattgtc ataacctaaa aaaggcactg ctaagcaaaa
    20641 gcagtgcctt gaaatatttt atttaaataa cacaaaaaca taattactca taagaaacca
    20701 attctgtatt atctaccatg aatgtaaaga acccctcatt aggcatcgga tgaaaataag
    20761 cattgatcac tcttatcaag gcattatggc aaactaacag atagacattt tcttcgtctt
    20821 cgatgcattc tttcaataaa ggaacgatcc gtgcatacac atctaagact gactccccat
    20881 ttgggaatcg tacagcgaac gctaaacgtg ctttttgaaa gttctcatct ttgcttggca
    20941 gtccatcata atccccaaaa tccatttcta ccaatcgttc atcaacggtc agcggcaagc
    21001 tgagacgatc agcaactgct tgtgctgtat ctcttgctcg ttgaagaggg gaatggatga
    21061 ttttcgtgat tggaacaggc aaatctacta ccttttctgc tagtttctgt gcctgcatct
    21121 gtcctttttc agtcagcggc acatctgccc gtccgcaaac taatccttgt gcgttccaag
    21181 ttgtttctcc gtgtctcgtt acataaagca tgtgattctc tccttcgttg gcaaagttcc
    21241 ccttaaccat accttgttgt tcttgagatt acaagggtta gattctctca agagaaataa
    21301 tctcagtaga tactttatcc aggaaggttt gatcatgttc cactagtaac atggcaggtt
    21361 tcacgttcaa gatcagttgt tctaattgtt cttgattgaa gacatccaaa taattcaatg
    21421 gttcatccca tgtatatagt tcagctggct gtgataaaga tttagccaat tccacttttt
    21481 tccgttggcc catactcatc tgctcgatct tgttatgaaa aacatctctt tccatcccaa
    21541 gctttcggag gttgttcaaa aatgcttggt agtctacttg gtttttctct gcaaattccg
    21601 ccaacgttcc tcgattgtct tcataatttt ggcttgcata actaatgctc agatgttttg
    21661 gctggtattt ttctcctata accttgccgt tgaatgcccc cagaagataa tggataatgg
    21721 atgactttcc tgcaccgtta ggacctgaaa tcgccacccg ctgatgaggc tcgattgtaa
    21781 aatgaattgg ctcgaataac agattttcat accctaattg aagatcttct acgcttaaaa
    21841 gtcgcttatg gtgagacgct tggctattca tcgtcaaaga atcgatatat tcgatatctt
    21901 ttaatagttt ttctttctcg ctgatctggg tctccatccg attcacgatt gctttggatc
    21961 gtttcatcgt ccgtgcagca tcagcaccca ctgctccttt attcactcgt ctagattcag
    22021 tatcgatgaa tccgacttgt ttctttgttt tatctccttc tcgggaacga gaccattcgg
    22081 ctttttcagc tgctgttttc tttagcctac tgacttcttt tttcaatttt tcattttgag
    22141 ccatttcaaa ttcatcacga agttttttct gttcttcata gatagagaaa ttcccttgat
    22201 aaagttccag ttgacttttt tcgattgcta aaacatggtc cactacttca tcgataaatc
    22261 cccggtcatg gctgaccacg atgaagcctt gttttttctt tttcaaataa gccgctactt
    22321 gttttctacc agagatatcc aaatgattcg ttggttcatc gattaacggg aaatgagtgt
    22381 catccacaaa taaaagtgcc agtaggactt ttgtcttctc tccccccgat agtgtgctga
    22441 attctctcca taagatttca ggatctgttt gcatcaattg gagctctctt tcgatttccc
    22501 atatctcaaa atccgtaata tcatttaaca cgtaataggt taaacgttct ttatcttttg
    22561 tctgttgcgg gaaataggca aattcttgct gatggattac ttgcccttga taaggtagtt
    22621 tgttttgtag aatattcagt aaagttgtct ttcctcgacc gtttcgtccg ataagtccta
    22681 gtttccattg tgtgtcaaaa tttagatttg cttgttcaaa taataatgtg ccttggctgt
    22741 cgtagccgaa tgtcagattt tttatttcga ttttagacat tttccatcac ctcgtaaaaa
    22801 aagaccagtc ctattttcag aactggctaa agaggatgca agggttggat acacacaaaa
    22861 agacccatac atcgaaaaaa ccaagccaat cccgaaaatc tgcacactgc ttccttgtct
    22921 ccacaaggta cagtctgaat gcagctttca tcaatcgact taatttttca atgcacggat
    22981 ccctcacttt gtcctatatt tgaaattacg atagcataaa gaaaatgatt ttgtcaacta
    23041 cttcgggagg atggtgaaaa atctgctaag tgtctgtcct aagatttttg ttttttctaa
    23101 tgtttgcctg tgttccattg cttcttctaa acctattgga cccaaatgaa tacttaagac
    23161 aattgggaga aaatcagaaa gtccttctag ctcttggtct ctacttccgc aaatagcgat
    23221 tattggtttt cgatattttt ttgcaagcac tgctacaccg tatggaactt ttccgtggat
    23281 cgtttgctga tcgatccgcc cttctcctgt aatgatgaca tctgcttgtt cgatcttttt
    23341 ttccaatcca gtgatttggc tgactaaatc gaaaccagaa accatcttcg ctcccaacaa
    23401 aaaaagggct ccaccaatac cgcctgctgc tccacttcct ggaatatcat ctaaatccac
    23461 ctcccagaaa tcttttattt gctgagcaat ctttcctgct tgtttatcta agaaagctag
    23521 cgtcgtatct attcctcctt tttgtcttcc aaattgccaa gcagctcctt gttgacctgt
    23581 atatggattg gtaacatctg cagcgataat caattttact ttagaaacaa gaacgtttct
    23641 tcgatcaaaa tgaagttttt tagtagataa taaaggattt ccttctgtgt acccttctaa
    23701 agaagcaccc aaggattgga gtaatcctag accaccatcg ctacacccgc ttcctcctaa
    23761 agtgacaata atttgttcta cttcttgaag cagtgcatct ttaataagtt ctcctaaggc
    23821 ataactggaa gcaagtcgga tagtttgatc cgttggttta tcaagtagat ctaaccccaa
    23881 tgcttgtgca gattcgatga ctgcggtgtt ttttccttgc caagttgtca ataaatagct
    23941 gatttttcgc tgacggaata agagatccat cccatcaatg gtacgccatg ttcccctgag
    24001 cgcgtaatag attgcttctg cagtattttc tccgccatct gcaatcggca cattgatttt
    24061 tcttccttta cgatcttccc agccatttag aactgcctga tttagttcaa atgaagaagc
    24121 acttccttta aatgaatcaa ttgccgccaa aatatccatc tgtatccctc actttcttct
    24181 taagtaagac actttttttc atttttttca aacaaaacaa tgctattttc ttccattttt
    24241 ctatatacta aaagggaact cattgaataa aggagagaaa aaacatgaaa atcgcaatag
    24301 ctggggccgg agcaatgggc agccgaatcg gattgatgct acatcaaagc ggaaatgagg
    24361 tcctcttgat cgatcgttgg cctgctcaca ttgaagccat tcgtacaaat gggttgattg
    24421 ctgactttaa cggtaaagaa gtggtcgcaa aactgccaat ctattcacca gaagaaatca
    24481 tcgaaagcaa cgaacacgtg gacttgatcg tagcattaac aaaagccaat caattagatg
    24541 atatgttttg ttcgatccaa tccattatta ctgacaatac ttatgttttg tgtttactaa
    24601 atggattagg tcatgaagat gtactggaaa aatatgtgcc aaagaaaaat atcttatttg
    24661 ggatcacgat gtggacagct ggtctagctg gtcccggaaa agtcacattg ttaggtgatg
    24721 gagaaatcga actagagaac ttggaaccag aaggcgaagc atttacaaaa aaagttgtag
    24781 aagtctttca agaagcaaat ttaaatccga tctatagcca taacgttcgt tattccattt
    24841 ggcgaaaagc ttgtgtaaat ggaacattga atggtttatg cacgattttg gattgtaata
    24901 ttgctgaact aggcgcgcaa aaagcggcag agagcatggt tcgaacaatc gtatctgaat
    24961 ttgcttctat cgcagcaaaa gaaggaatca tactagatca agaagaagtg taccaacata
    25021 ttgcttctac ttatgatcct gacaacatcg ggttgcatta cccatctatg taccaagacc
    25081 tgatcaaaaa ccatcgtttg actgaaatcg actacatcaa tggtgccatt tggcgaaaag
    25141 gacaaaaata tgatattgct acaccatatt gtgccttttt gacccaatta gtccatgcaa
    25201 aagaaggaat ccttggcgca gaataaaagg ctctctgatg agaatcagct gaatcagcag
    25261 ctggttctct ttttttaagc ccaataaaag atcaaaaaga aaacacaact ctcatgatgc
    25321 cataagaatt gtgcttgttt gtttcagtac ataatctctt caaaatgtag gttttttatt
    25381 tgttttcaac agaggagagg tcatattcgt attgctcata aatagtggaa tcgttagtga
    25441 taaatcgttt tgcccaattt tctgcatcat aaaattccaa tagctctgat aggattggct
    25501 taaatggtgt atgcagaaat tccggtaatt catctaaatc acgttctcga agcaaaaaaa
    25561 tattttcagg acgataaaaa tgataatgag caatcgcttg attatccgtc actagtttct
    25621 tttgaaaata catggattca aatgtccgca aagtcactcc ttgctgaccc tcccgcaaca
    25681 gttccagaat cccgcgcgat tcccctgttt ttttcaggta ctcttcataa gtaagatatc
    25741 caggttgttc attccctcga tgtggaagaa tgaaatagtt ggtcgtaaca tctcttttta
    25801 taaattcctg cttatagctt tctgctcgtt cttttctccc attattcgtt gcaccaaaaa
    25861 atagatccgt ctttggttcg ctagaagaaa aattcatatg tttcgaataa aatgaactat
    25921 tatgtttcag cccaagttct tttgcttcca aaaaatcaaa atgataaatc tcatcgattg
    25981 ccggttcatc ttgtgcctgc ttcagcatcg cctcgtgttc tgctttgaag tgattccaaa
    26041 aaaataacac aatttttgca ttggtaaatg ggcgcacgcg tcgagccatc tccatatcaa
    26101 atccataatc taaaaaaacg atcagctgat aatttgccaa ctgttgtcta gctgatttaa
    26161 tgaattccga ctgtagtaaa tcttttccgg accaaacatc taaagagcgg atggaaggca
    26221 aaaaataaag tgatttattt tttgcaacta gcagtacgtc atttttgttc atcttttccg
    26281 cctcactttc tctgtcactt tttcctatga tagcctgttt aaatagtaaa aagccagtaa
    26341 aacgtttcct atatttgtat gaaaatttaa catttgtatg aaaatatgat gaaataaatc
    26401 attcttctat taaaattcgc ctaaaagttt tctgaatagt tgtaattgtc tgaaaatttg
    26461 ttatcattag tcattgttaa atattgctat ttattcttaa tataaatttt gattgtgaat
    26521 ttaaaagaaa gaggtcattt atggaagata aaaaattgaa aaaacaactt agctccagac
    26581 atatcaccat gttagcttta ggtggagcaa tcggtgcagg tctatttaaa ggaagtggcg
    26641 aagcgattgg gatcgccggc ccttctgtat tgattgcttt tttgattggt gggctgattt
    26701 tatatatcgt gatgaaaggt ctgggaaaaa tcgttttaag cggtggcgac acgcatcacg
    26761 gattatctgg tttgatacgc ccttatctag gtgctcattc tgctgatttt actgattggg
    26821 tctactggtc tatgtggatt atcaatatca tcgctgaagc tgttgcagct gcttcctttt
    26881 tgcagttgtg gttcccgcac attccagcct gggtatttgt ttttatgttg gctgttttaa
    26941 ctacgatcat caatctttat tcggtacggt tattcgcaga aacagaatat tggctggctt
    27001 ttgctaaaat cagtgtcatt atcttactga tcatttttgc tacttatctt gtcggtcagc
    27061 aaatgttggg cacaggcgtt ttccctaccc ttcagcaatt gactgaccat ggtgggttta
    27121 ctcctcatgg tatgaaggga atcatcagtt ctttgcttgt agttatctat tcttacggcg
    27181 gttctgaact gattgctatc acggtaagcg aagcagatga tcctaaacgt gcgattccta
    27241 aagcaatcaa aggtgtcatg ggaagaatca tttcctttta catcattcct ttgtttttgc
    27301 ttttgattct ttttccttgg aatactttag caggcacgaa tgtcagtcct tttgtgatgg
    27361 tatttgaaaa aatgaatatc ccatttgcag cggatatcgt caattttgtg attgtccttg
    27421 ctttgttctc atctatcaat tcgggtgtgt atgcatcttc aagaattttg ttcttccgtt
    27481 tgaaggatcg aaaaggttcc tctagaaaac tagctgtttt aaacaagcat caagtaccgc
    27541 aacgtgctgt tttattttgt accagtgttc tttatcttgg tgtagctctt tcttattttg
    27601 tcggtgacaa attatttggc tatctggcag gttccctttc gtatacagta ttattgatct
    27661 ggatcattat cagtgcggca tcctttgtac tggcactaag aaaaggaaca ttatgggata
    27721 aaggaatcag cttttttgca ttagctgtct taggattgat tttccttggt atcctgttca
    27781 cgaactccat tggggtaact gtattgactg gcctgcttta cctgttcatt tatttcagtt
    27841 atcaaaaaaa gaatgatgcg ttcgtattga cgaatgaatg aaatcgatag aaaattttat
    27901 tttatttatg tggaatagat ggagctattg aagaaaggag ttgtgacaaa agtcttgttg
    27961 caactccttt ttccgaataa acagtctcat gacctcttgg taaacggtgt tcaaaaaccc
    28021 tctgtgcaaa ataattgatt gttctccatg ctcatgacat gatagaagaa aggaatgaaa
    28081 aaaaggagtt tgttttaaat gaaaaagtat tggaagtttt tgttgatgat cggtgtttca
    28141 acggtagtta tgtttggtat gatgtacttg aatgtctatg cgctcgatca tatcttcttc
    28201 agtcgtacac gagtattcat ggcgttgatg atgggtgcag tcatggcagt catcatgctg
    28261 ttgttcatgt ggaaaatgta tgaaaacaaa aagataaatg ttatgatctt agccgctagt
    28321 cttcttgttt ttgccggttc cttgtttatg gtacgaagcc aaactactgt caacgacaca
    28381 gcttggatga aggccatgat tcctcatcat tctatcgcta tcctggcaag taaacgagct
    28441 gatttaaaag atcctgaagt aaaaaaatta gcggaagaaa tcattcaggc acaagaagaa
    28501 gagatcgaca aaatgaaaaa aatgatcaaa gaaatggaat gaccattatc cgtccaaata
    28561 aaaaaagagg atgttccaga agttatcagc ttcaagaaat aagaagaagc tacttctgga
    28621 acgccgtgaa taaggggttg tgaaaaagct gccctgcatc aagtaataag aacagccaaa
    28681 caaaaatagc ttctcctatt tttcgtttgg ttaggcttat taccgcagat gcaagctttt
    28741 gaacaccgtt tattaagagg ttgtaaaatc agcgttctga cctgagtatt agagagacaa
    28801 atggaaaaat agttcctcat attttgccat tttttgagct aataccgagg gtcagctgat
    28861 tgaacaccgt ttatcgagag gttgtgaaaa agtcgcttag tttcgcgtat taagaaaaat
    28921 tttgtgaaat ggctttccac atttttgtat aaatttggct taataccgag aaactggctt
    28981 ttgaataccg tttattcgta aaagggattg tgacaaaagt cttgtcacaa tcccttttta
    29041 tgtttt
//
LOCUS       DAFBSV010000029        28829 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.030, whole genome shotgun sequence.
ACCESSION   DAFBSV010000029 DAFBSV010000000
VERSION     DAFBSV010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28829
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.030"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(43..681)
                     /gene="plsY"
                     /locus_tag="LLB18_001197"
     CDS             complement(43..681)
                     /gene="plsY"
                     /locus_tag="LLB18_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBK5244210.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            808..1242
                     /locus_tag="LLB18_001198"
     CDS             808..1242
                     /locus_tag="LLB18_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBK5244211.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            1408..3453
                     /gene="parE"
                     /locus_tag="LLB18_001199"
     CDS             1408..3453
                     /gene="parE"
                     /locus_tag="LLB18_001199"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HBK5244212.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            3465..5915
                     /gene="parC"
                     /locus_tag="LLB18_001200"
     CDS             3465..5915
                     /gene="parC"
                     /locus_tag="LLB18_001200"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HBK5244213.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDRSIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            6192..8423
                     /gene="pflB"
                     /locus_tag="LLB18_001201"
     CDS             6192..8423
                     /gene="pflB"
                     /locus_tag="LLB18_001201"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBK5244214.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            8667..9428
                     /gene="pflA"
                     /locus_tag="LLB18_001202"
     CDS             8667..9428
                     /gene="pflA"
                     /locus_tag="LLB18_001202"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBK5244215.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            9513..10439
                     /locus_tag="LLB18_001203"
     CDS             9513..10439
                     /locus_tag="LLB18_001203"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HBK5244216.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            10621..11514
                     /locus_tag="LLB18_001204"
     CDS             10621..11514
                     /locus_tag="LLB18_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HBK5244217.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            11648..11773
                     /locus_tag="LLB18_001205"
     CDS             11648..11773
                     /locus_tag="LLB18_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5244218.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(11907..12539)
                     /locus_tag="LLB18_001206"
     CDS             complement(11907..12539)
                     /locus_tag="LLB18_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244219.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(12687..13229)
                     /locus_tag="LLB18_001207"
     CDS             complement(12687..13229)
                     /locus_tag="LLB18_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HBK5244220.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            13364..13753
                     /locus_tag="LLB18_001208"
     CDS             13364..13753
                     /locus_tag="LLB18_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244221.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            13757..14521
                     /locus_tag="LLB18_001209"
     CDS             13757..14521
                     /locus_tag="LLB18_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBK5244222.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            14650..15597
                     /locus_tag="LLB18_001210"
     CDS             14650..15597
                     /locus_tag="LLB18_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5244223.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            15727..16467
                     /locus_tag="LLB18_001211"
     CDS             15727..16467
                     /locus_tag="LLB18_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244224.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(16758..17426)
                     /locus_tag="LLB18_001212"
     CDS             complement(16758..17426)
                     /locus_tag="LLB18_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBK5244225.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            17560..17847
                     /locus_tag="LLB18_001213"
     CDS             17560..17847
                     /locus_tag="LLB18_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244226.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            18263..19801
                     /locus_tag="LLB18_001214"
     CDS             18263..19801
                     /locus_tag="LLB18_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HBK5244227.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            19798..20763
                     /locus_tag="LLB18_001215"
     CDS             19798..20763
                     /locus_tag="LLB18_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5244228.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            20750..22072
                     /locus_tag="LLB18_001216"
     CDS             20750..22072
                     /locus_tag="LLB18_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBK5244229.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      22135..22239
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            22313..23056
                     /locus_tag="LLB18_001217"
     CDS             22313..23056
                     /locus_tag="LLB18_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5244230.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            23071..24063
                     /locus_tag="LLB18_001218"
     CDS             23071..24063
                     /locus_tag="LLB18_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK5244231.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            24075..24812
                     /locus_tag="LLB18_001219"
     CDS             24075..24812
                     /locus_tag="LLB18_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5244232.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            24802..25524
                     /locus_tag="LLB18_001220"
     CDS             24802..25524
                     /locus_tag="LLB18_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBK5244233.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(25608..26231)
                     /locus_tag="LLB18_001221"
     CDS             complement(25608..26231)
                     /locus_tag="LLB18_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBK5244234.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQP
                     VVQETVQTEKQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYI
                     GRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            26626..27317
                     /locus_tag="LLB18_001222"
                     /pseudo
     CDS             26626..27317
                     /locus_tag="LLB18_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
     gene            27525..27815
                     /locus_tag="LLB18_001223"
     CDS             27525..27815
                     /locus_tag="LLB18_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244235.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT        10005 a         4823 c         5950 g         8051 t
ORIGIN      
        1 atttgtcaca ctcccgtttt atctctttgg aatgaaaaag tatcaggatt ttttcttgct
       61 gctattcaaa ccaaacggga ttcgactttc agtatggttt ctgatacgct tgatattgtc
      121 tttatgccga taaaagataa aggaagaaac taaaaaggca atgatcgtca gtaaccaatt
      181 gggcttagcc aaaatcacag gagctacata aggaaggacg atcgtagata aagtgatcaa
      241 tactgcactg atcatactgc tcaaactcac catacttgta caaaataaac taacgataaa
      301 gatgatacaa gaataaacaa aaaatacagg attaaatcct aaaagcattc ctgcacttgt
      361 cgcaacagct tttcctcctt tgaacccagc aaaaatcgga aatgtatggc caagaatggc
      421 gcatacccca aaccaaagag ggttaatccc agaaaggtgg aagatcatcg gcaaacaagt
      481 agccaatgta ccttttaaaa tatccataag caggacaaca atcccggctg ttttgcctaa
      541 tacacgaaat gtattggtcg ttccagtatt accgctcccg tgttgtcgga tatctttttt
      601 gaaaaacaat ttgccaatcc agacaccgga aggaatagaa cctaaaagat atgctaaaat
      661 aagtaataag atcaatttca ttttttaccc tctttcaagt tgaaaactat cctttatttt
      721 agcatgaata ggtaacagga acaattgaaa aaatgaaaga tacaagtata atagatggaa
      781 taaaaagaaa agcaaggggt ggcagaaatg tctgtaaaaa atccaacaca agaaacgatt
      841 ttcaactatt tggaagaagc aaaaaatatt gccgtcgtag gcttgagcaa taaaccagaa
      901 cgaacaagtt acatggttgc acaggtattg caagacaatg gatataaaat cataccagta
      961 aatccattat tggctggtga agaaattcta ggcgagaaag tctatgcgaa tttgacagaa
     1021 atcgatgatc caatcgatat cgtagatgta tttagacgga gtgaattttt acctgaaata
     1081 gcaggtgatt ttttgaaaac tgatgctaaa gtgttctggg cacaattagg gattgaaaac
     1141 aaagaagcag ctgagatgct aagaaaagca ggacgtacag atatcgtaat ggatcgttgt
     1201 attaagattg aacttggtaa gttgaaagaa aaccaaaaat aaaaatgacc acaaagaaga
     1261 gatgatcgat agaggggaat gtcgaaaaag cggttaggag ataattaaaa ttgatttctc
     1321 gtctaccctc ttttttttca cgaccttttc tagtatgata atcgtggtgc ggttttgccg
     1381 caaagtatta ttgaaggagc gtttgccttg gcaaaaaaag taaacaacga atacaatgac
     1441 tcgtccatcc aagtattgga aggattagag gcagttagaa aaagaccagg gatgtacatt
     1501 ggatccactg acagccgagg cttgcatcat ttagtctatg aaatcgtcga taatgcagtt
     1561 gacgaagcat tatcaggtta tggcagtgag attgatgtga ccatccatga agacaatagt
     1621 ataactgttg cagatagcgg acgtgggatg cctgtaggaa tgcatgcttc cggaatacca
     1681 acagttgaag tgatttttac tgtgctgcat gctggcggaa agtttggtca aggagggtac
     1741 aaaacttctg gtggactgca cggtgtagga gccagtgtgg taaatgcctt atcgaaatgg
     1801 ctaattgtaa cgatcgttag agatggcgta gagtatcagc agaaatttaa aaacggcggt
     1861 aaacctgacg gtactttgaa aaagatagga aaaacaaaaa aagcaaacgg gacgactgtc
     1921 cattttttac cagatgatac aatattcagt acaacgaaat tttcatatga aattttagcc
     1981 gaacggttaa gagaatctgc ctttcttcta aaaggcgtta aaatctctct ttctgatctt
     2041 cgtggagaag aaccagtcaa ggaaattttt cattacgaag aaggaatcaa agaatttgtt
     2101 gattatctga atgaagaaaa agatacattg acaccagttg tttatttttc aggagaaaaa
     2161 gaaggtatcg aagtagaggt cgcttatcaa tacaatgacg gttattcaga aaatgtttta
     2221 tcttttgtca ataacgttcg gacaaaagat gggggaaccc atgaagctgg tatgaaagcg
     2281 gcgatgacga aatcttataa tgaatatgcg agaaaagttg gtttgctgaa agaacgggac
     2341 aagaatctgg aaggtagtga tttcagagaa gggttagctg ctgtactttc tatccgtgta
     2401 cctgaaaatc ttctgcaatt tgaagggcaa acaaaagaaa aacttggtac gccagttgct
     2461 cgtaccgtag tagataacgt catcagtgaa caaatgggct tttatttgca ggaaaatagc
     2521 gaaatgagcc agatgttggt ccgtaaagca atcaaagcca gagaagcgag agaagcagca
     2581 cgtaaagcca gagaagaaag ccgaaatggg aagaagcgta aaaaaggcga atctcttctt
     2641 tcaggaaaat tgacacccgc acaatcccga aaccctaaga aaaatgaatt gtatttagtc
     2701 gaaggggatt ctgctggcgg atctgctaaa caaggaagag acagaaagtt ccaagcaatt
     2761 ctacctttac gaggaaaagt catcaatacc gaaaaagcta aaatgcaaga tatcttgaaa
     2821 aatgaagaaa tcaatacgat gatctatacg attggtgcag gagtcggtcc tgagttttct
     2881 atcgaagact gtaattacga caaagtaatc atcatgaccg atgcggatac agacggcgcc
     2941 catattcaag tattactgct tactttcttt tatcgttata tgaaaccgct gattgaagct
     3001 gggaaagtat atatcgcgtt accgccttta tataaagtat ccaaaggaca aggaaagaag
     3061 caagtcattg aatatgcgtg gacagatgac gaattggcag caatgattaa aaaagtcggc
     3121 aaaggatata tgctgcagcg atataaagga cttggagaga tgaatgcgga acaattgtgg
     3181 gaaacaacga tggatccgac ttcccgtacg ttgatccgcg tccgtatcga tgatgctgcg
     3241 caagctgaac gtcgagtaac cacactgatg ggtgacaaag tagaacctcg aagaaaatgg
     3301 atcgaaaatc acgtgcaatt tacgctcgaa gaagatggca gtatcttaga taaaaaagag
     3361 gatactgaaa tctctccttc agtttctaat gatttattag atgaagaacg agcagataaa
     3421 aatgaaaaca atcagttatt tgaagtagaa taggaggtca cctgatggaa aatcgacaag
     3481 aagtacaaga attaacttta gaagaagtga tgggtgaccg cttcggacgt tattccaaat
     3541 atattatcca agaacgtgca ctgcctgata tccgtgatgg attgaagcca gtgcaacgcc
     3601 ggatattatt tgccatgaac aaagatggca atacgtatga caaaggattc cgtaaatcag
     3661 caaaatctgt cggaaatatc atggggaatt atcatcctca tggtgaccgc agtatttatg
     3721 aagcgatggt ccgcatgagc caagactgga agttgcggga agtactgatc gaaatgcacg
     3781 ggaataacgg gagtatggac ggtgatccac ctgctgcgat gcgttatact gaagccagat
     3841 tatccaagtt aagtggagag atgctagcag atatcgagaa agaaacagtc gatctcgtgt
     3901 ggaattttga tgatacagaa aaagaaccaa cagtccttcc agctcgatac ccaaaccttc
     3961 tcgtcaatgg atcgacaggt atatctgctg gatatgcaac agaaatcccg actcataact
     4021 tagctgaagt gatcgatggc acaatctata tgatcgatca tccacaagcg agccttgaaa
     4081 aattgatgga atatattcct ggacctgact ttccaacagg agggatcttg caaggaaaag
     4141 atgaaatcaa aaaagcttat gaaacaggac gaggaaaagt tattcttcgt tcgaaaacaa
     4201 agatagaggc aatgaagggt aataaacagc aaatcgtgat cacagaaatc ccatatgaag
     4261 taaataaagc gaccttggtg aaaaaaatgg atgagatccg tttgaataag aaaatcgatg
     4321 gaatagctga agtacgagat gaaagtgata gaacaggtct gcaaattgtc gtcgaattga
     4381 aaaaagacgc caatgctcaa ggaattttga attatttgtt caaaaacact gagctacaga
     4441 tcaattacaa tttcaatatg gtcgctatcg accatatgac tccgcatcaa gttggactga
     4501 aagacatttt aagaagttat atcgagcatc gaaagcaagt cataacaaaa cgtagtcaat
     4561 tcgatttagc caaagctcaa aaaagacagc atatcgtaga aggattgatg aaagctttat
     4621 cgattctgga tgaagtaatc gcaacgattc gtgaaagtaa agacaaaaaa gacgccaaaa
     4681 agaatttagt cgacgtcttt caatttacag aagaacaagc agaagcaatt gtcacattgc
     4741 aattataccg tttgacgaac acggatatca cagagcttca aaaggaatcc gaaagcttga
     4801 ttgcgcaaat cacagagttg aataaaatcc tttcaaatga caaagagctt ttctctgtta
     4861 tgaaaaaaga attgcgagaa gtgaaaaaaa attattcttc cgctcgtcta acgacaatcg
     4921 aagacgaaat cgaagaaatc aaaattgata cgcaagtctt agtggcacaa gaagacgtaa
     4981 ttgtcagtgt gacgcgagaa ggctatgtga agcgaacaag ccttcgttct tatagtgctt
     5041 ccaaaccaga agaaatcggg atgcgagaag gcgactactt gctatactca ggtgaattga
     5101 gtacattgga ccatgttctt ctgatcacaa ataaagcaaa tgtgatctac cgccctgtcc
     5161 atgaactacc cgatttgaaa tggaaagatg ctggtgagca catttctcaa acaatctcca
     5221 atctgtctgt agacgaatcg attttagctg ttttcccata tcaaaaaatt caagcagaga
     5281 aaacatttgt attcatcagc aagaatggat tgatcaagca aacacgaatg acagagttcg
     5341 aaccatggcg cacctataag agccgtccgc tcagctgtat gaagctaaag gcggaagaag
     5401 atgaactgat tgctgtgtat ctgaaagaag atcagccagg cttagatgtt ttcttagtaa
     5461 cgcatcaagg aatgggtttg cgctatcctt taacagatgt tcccgttgtt ggagcaaagg
     5521 cagctggagt gaagtctatg aatttgaaag atggagatag gattatcaac gggctgcttg
     5581 tgttagcaga aggtgatacg ccgatcgtaa tcgttactca gcgaggagct gttaaacgca
     5641 tgcttgctca agaaatcagc caaacttcac gtgcgaagcg gggagtgacg gtcatgcgtg
     5701 agctgaaaaa aaatccgcac cgtattatct atatgtcgga aggaagatca aaagaaataa
     5761 ccttgatgaa tcaaaaaggg cagcagttaa cgattgaccc aactgatttc cctataggtg
     5821 atcgaacatc gaatggatca tttgcgatgg atgagaaaaa aggtggagaa gtcatcgaag
     5881 ttatcgatgc tcctgagatt ttcatcgagt cgtaactgtt gtagtatttt aatgaagaga
     5941 cgccatctgt attaatacag gtggcgtctc tttttcattc atttttaata aatccttata
     6001 cgtttgcaaa aaaagatgaa agtgttcaca atgcttaaat gttggtatgt caacgttgat
     6061 ttaaatatat gtaaataaaa cataaaaatt gttaaataaa aaacaagaaa acccttgcaa
     6121 agatagggtg ctgtgttata ctaatcacgt aaaaactgtt acataaaaca gaaatttagg
     6181 aggtccatac aatggagcaa tggaatggat ttaaaggtac caaatggaaa gaaggcgtag
     6241 acactagaga ctttattcaa aataactaca ctgaatatcg cggtgatgac agctttttgg
     6301 aaggcccaac agaagcaaca gaaaaattat gggatgaatt gcaaaagtta aatgatatcc
     6361 aattcgagcg taacggtgtc tatgatatgg acacagaaat cgtatcaact attacttcac
     6421 acgatgcagg ctatttggat aaagatttgg aaaaaatcgt cggtctacag acagacaaac
     6481 ctttgaaaca agcattcatg ccgttcggcg gaatcaatat ggctaacaat gcgctaaaaa
     6541 gcaatggcta tacaccaaac gatgaattga cacatatttt cactgactgg cgcaaaacac
     6601 ataatcaagg tgtatttgac gcttatactg ctgaaatgcg tgctgctcgt aaaaacaaaa
     6661 tcattacagg gcttccagac gcttacggtc gcggacgtat catcggtgac tatcgtcgtg
     6721 tggcattgta tggaatcgac tatttgatgg aacaaaagaa aaaagatcat gatatgactg
     6781 gttatcatac aatgagtgaa gaagtgattc gtttacgtga agaaatcact gaacaatatc
     6841 gtgcattagc gcaaatgaaa gaaatggctg cgaaatatgg ctatgatatt tctaaaccag
     6901 ctgcaaatgc aaaagaagct gtccaatggc tatacttcgg atatttagca gcaatcaaat
     6961 cacaaaatgg tgctgcgatg tcaatcggac gtatctcagc attccttgat atctatatcc
     7021 aacgtgattt ggataatgga gtaatcacag aaaaagaagc acaagaattg atcgaccact
     7081 tagtaatgaa attacgtatg gtcaaattcg cgcgtacacc tgaatataac caattattct
     7141 caggattccc tatctgggct actttatcca ttgcaggtat gggattagat ggtcgttcat
     7201 tagttacaaa gaatgatttc cgtctgcttc atacattaac aaatatggga ccttcaccag
     7261 aaccaaactt gactgttttg tattctgaac accttccaga aggattcaga acatatgcta
     7321 gcagaatcgc tatcgaaagt tcttcgattc aattcgaaaa tgataatcag cttcgtgaac
     7381 aatggggttc tgatgattgt gcgattgctt gctgtgtatc aggaacagtt gtcggaaaag
     7441 acatgcaatt ctttggcgct cgtgctaact tggctaaaac actattatat gccatcaatg
     7501 gcggagtcga tgaagtgact ggcgcccaag ttggaccaga atatcgtcca atcacatcag
     7561 aaatactaga ctttgaagaa gtgaaacata acttcatgaa tatgatggat tggttagcag
     7621 aactatatgt caatacgttg aacatcattc attatatgca tgataaatat tcttatgaag
     7681 cagctcagct ggctttgatg gattctgact tgcaacgcac atttgctaca ggtattgctg
     7741 ggatctctca tgcggcagac agcttgtcag cgatcaaata tgcaaaagta aaagcaatcc
     7801 gtaatgaaaa aggaatagca gttgattttg aagtggatgg cgacttccct aaatacggaa
     7861 atgatgatga ccgtgcagat gaattagttt catggatctt ggaatacttc atgggacaaa
     7921 tcaaacgtca taaaacttac cgcaactcaa aaccaacaac ttcattattg acgattactt
     7981 caaatgttgt ttacggtaaa aatacaggaa atactcctga tggccgtgaa gctggaaaac
     8041 cacttgcgcc aggagcaaat ccaagttaca atgcggaaca aagtgggtta ttagctagcc
     8101 tgaactcaac agctaaaatg aattacggct gtgcattgga tggaatttca aatacccaaa
     8161 caatcaatcc ttcaggtctt ggaaaagaac aagatacaag aatcgaaaac ttgcgtaatg
     8221 tcttagatgg atacttctca aaaggagctt atcatttgaa tgtcaatgta ttcagtaatg
     8281 atttattgcg tgatgcaatg gaaaatccaa tgaaatatcc gaacttgacg atccgggtat
     8341 ctggttatgc agttaaattc cgtgacttga caagagaaca acaattagat gtcttgatga
     8401 gaacttcaca cgacagaatg taaaaagttc gtgaaaaaag tttttcgact tagcgtcgaa
     8461 aggacgttga atagccattg catcaaaatc gaataatcag tatgcttatt tgaaagaaac
     8521 gatttacagg ggcaggactt gtatgttccg tccctgtaaa ttttacacat aacgaagcgg
     8581 caattgcgaa aaattttgtt cagaaagctt cgcttcgaca gctaacttgt acttaaaatg
     8641 aaatcaaaga aaagatgtga acttaaatgg aagaaaaaac aatcggctat gttcattcta
     8701 tcgaaacttt cggttcagta gacggacctg gactgcgctt tgtcgtgttt atgcaaggat
     8761 gccgcatgcg ttgccaattt tgtcacaatc cagatacttg gaatattggc ggagggaaag
     8821 aatacacagc agatgaactt ttagataaag cagaacgctt cagaccttac tggggagata
     8881 aaggtggtat tactgttagt ggtggagaac ctctattgca gatcgatttt ttgatcgaac
     8941 tatttaaaaa agcaaaagag cggaagatgc atactacatt ggatacatgc ggaaaacctt
     9001 ttacgtatga agaacctttc ttttcacgtt ttcaagaatt gatgaagtat acagatttac
     9061 tgttatttga catcaaacac atcgataatg aagagcataa aaaactaacg cattgggaca
     9121 atgaaaatat tttagaaatg gctcaatatt tgtcaaaaat caacaaaccg gtttggattc
     9181 gccatgtact agttcctgag cgaagtgatt atgatgaata tttgatccga ctagacaact
     9241 ttattcaaac cttgtcaaat gtagacagag tagagattct tccttatcat acgatgggaa
     9301 aatacaagtg ggaaacactt ggtttgaaat atccattaga agggatcgaa ccacctacaa
     9361 aagaacgtgt cgaaaatgct aaacgattgc ttcatacaga agagtataca aaatatttaa
     9421 cgcgataggt cgcatcggaa agaagataag tattgcttct ttccgttttt ttgctattat
     9481 taaataggag aaatcacaaa ggagcgaatg acatgtcaaa aattttagtt tttggtcacc
     9541 aaaatccaga tacagatgca atcggggcag ccattgcgtt ttcacacttg caaaatgaat
     9601 taggtaaaga aacagaagca gttgctctag gtacacctaa tgaagaaaca caatacgcat
     9661 tagaccactt tcagctatct gcaccacgag tagtagagtc agctaaagca gaaaatgcag
     9721 atgtcatgct tgtggatcat aatgaattcc aacaaagtat ttcagatatc agcgaagtaa
     9781 atattttagc tgtagtagac caccatcgta ttgcaaactt tgaaacagct aatccattgt
     9841 actatcgtgc agaaccagtt ggatgtacaa gtacgattat tttaaaacta tataaagaaa
     9901 accaagtaac aattcctaaa gaaatcgcag gaatcatgct ctcagctatc atttcagata
     9961 cattgttgtt caaatcacca acatgtacgc ctgaagatga agcagctgca aaagaacttg
    10021 cagcaatcgc tgaagtcgat ctaaacactt atggacttga aatgttgaaa gcaggaacaa
    10081 atctaagtga taaatcagct gcggttcttc ttgatttgga tgcaaaaagt ttcccaatgg
    10141 gcagttccaa cgttcgtatc gctcaagtca atacagtgga ccttaatgaa gtgatggatc
    10201 gacaagcaga gctagaagca gcaatggaag atgaaatgaa agcaaatggc tacgatctgt
    10261 tcgtattagt tgtcacaaac atcttagaca gtgattcaga attacttgtt gctggtaaag
    10321 gaaaagaaaa agtagaagaa gctttccaaa caactttgac caacaaccgt gctttgctta
    10381 aaggtgtcgt ttcacgtaaa aaacaagtcg tacctcaatt gacggctgta tttagctaat
    10441 caaatggtag tatgaagcat tcaaaatgaa tggataagcg attgatataa aaagaaacat
    10501 agaacatact aaaggccgaa gaaatggagg agaataacag tcaattatga ctcttgttct
    10561 tcctcctttt tacgtaaaag ccttttaagt aaaataaaac ggatagaaaa gagaacatat
    10621 atgaactatt attcaaaaaa taaggaaaac ttttatcaaa aactgaccga tgatccgctt
    10681 ttttcttcat tgaccgatta tctatatgaa catcgagaac aagaaacgat tctaagagaa
    10741 ttgaaaaaag aattttcgca aaataaattt tcccattttc ttgatttatt gatcgatgca
    10801 ggattaatca agagggaaga acgaagatat catttgaact ttccaatatt tgatcctaaa
    10861 gattacttgc aacaagccac ttcggctgct gaaaccatag ctgaacaatt gaagagactc
    10921 tctgttgatg aacaaaaatt agcgatggga gaagttattt gggcgtattg tttcgaagat
    10981 gaacggaaag aagcgtattt ttatggagta agaaacagcc gagagacaga attgctgagg
    11041 acaactgcag gaaatgagaa gtaccgtttt atcacacttt cctctataga acacttcccg
    11101 cttactttgg ctaattactt ttttgtacag aagaatcagc ttcctgtaac gaaggcattc
    11161 aaagaattag ccgaacttat tggagacgta aatgaatcgt acttttttga tcaaatagaa
    11221 gttatcgttg acaggatacg taagaataaa tataaaaatc gccggcctag tattttccat
    11281 cagtctctac ttgtgacgaa tactataaag gaagaagaat cattcacatt agaattacct
    11341 attgtcgaaa aaaacaattt tgagattgaa ttaccaacat tggatccttc attgacaatg
    11401 gaggaaatgg cctttcttaa acgacaaatc ttttctgagc tgagcaagaa atttataccg
    11461 catgcatttt cttatatcaa agaatatgga acagttttag tgagtaaaac ctaagagagc
    11521 agtaagcaaa aattatactg actcttgcag gaggagcctt tctcttcctt tatggttaaa
    11581 agaattattt gagtattttg cctatctacc acctattaga ttcactacat ggtctggaaa
    11641 caaaggaatg caaaaaaatg gtgagaaatg tggaatgaca aaggaagtag tgataagaaa
    11701 agttagattt ttaaataatc aatattatga ttcagtcaag tatggcattt tatgggaaga
    11761 actagctgat tagattagga agtccatttg ataatccaga atcactaaga aacgaatggc
    11821 gagtcattaa taatttatcc aatcttgggt tattctttta gattgaagtg tttaaaacta
    11881 aaaaagcatt tatgaagtcg taatagtcag gcttcaaaat gctttttatt ttgtttgttt
    11941 tttctttgcc acataaatac acctagactg acgatgaaga gcatatccaa cagatttcct
    12001 gcgacttgga tcgtcgaagg gttggtcagt ggcattaaag caaggacaaa aaaggaaaac
    12061 aagctgtaaa taaaacaggt gacaggaact aatcgaaaga agagcggaca tttcaattgg
    12121 ctaaaaatga gtgaaaaaat aaaataagta aaaatggata aaatcacgac taaaccattc
    12181 atgataaaga agaaaagcgt attgtgatta aacgaataaa aaagaattgc taaaaaagaa
    12241 aacgttttaa atgcaatcaa tacgcttgaa gcttcgttta acgtaccagg atgtcgatga
    12301 aaaaaatagg caccgaaata aacagaaaac agtaagccgc aaagagaaga caaaatcaaa
    12361 aaaaacggat tttcttcggc ttctgtgata tcagaatgat ccaaaagcaa ccagcctaat
    12421 gcactagaag gcgcatgtga ggtcttaagg tatgaataac atagaaaaaa taagatcgtc
    12481 aaagttgcaa aaaaagagcc taaatgtaaa aaattagtgg ttctacgttg aatttccata
    12541 atatctccaa attaaattga taagtatata aagtataata acaaattgat gagtatatgt
    12601 cgatgttttt taatcaaaat aataaataaa aactgtctaa catttaaaat ttaatttaga
    12661 tattagacag tttttaagtt tgtgagttat tttccttgtc gttttctcac ttttttagtc
    12721 cagaaaccac ctgaaatata ttttggctca taagaaatga taaaagcacg ctcttcgatt
    12781 tctttgatca ggcgatacag ttcacgttcg ctttttctag gagaaagtat ttcgagaact
    12841 agccgctcac cttccagccc cattgcagaa gtctgtgtca caccataacc gtgttctctc
    12901 agtatacccg gcaaactttt atcttctgcg ctatttgctg gcaaaatcgt tgtgaccatg
    12961 atgtatccta atgccaattt gtcttcaatc aaaattccga cactgatacc tactgcgtaa
    13021 cctaacgcat agacaaataa attcagtgga ttatctaaac gatctaaaac aagggataag
    13081 ccgacgatat aaatcgtgat ctcgaccata ctgacaagtg gagcaatcag tcgatagcct
    13141 ttcattgtca acatgaaacg taacgtgttc agagtgatat aagcaaaatt aatgaggaag
    13201 atcatcccca acatttttgg atcaatcatt tgtaaaactc ctttcattta tataacaaca
    13261 atatcaaaaa aaatcgtaag tgaagaaaaa ttgaaacttt atacatacaa aaaaatgata
    13321 aaatgattat aatagaatta taaagatagg ttaggtgatt aaaatgaaaa cggtcaatcg
    13381 tgtgttttgt gccagccacg tgctaagtct ccttctcagt atatacttag gtgtctattc
    13441 gattcaacag ccaattgagg tagagaacat tgtttttcag atgtcgctga cagatggttt
    13501 aattttaagc gtttttttct ttttgatact gtttattggt aatattttcg gtagcgttgc
    13561 cagttttttg aatttttcta tttatccact cctttcgcta gcattaggag tggtgggact
    13621 ttgttctctg tgcttatttc ccgagccatt cagtcctgca tttatattat ttggtacact
    13681 gaacctgttc cagacaactg ttggagcatg gttgctatgg cgatcaggaa atttaatgaa
    13741 aataggtgag taacaattga atccaattat attgaaacgt tctgtccatc atattccagt
    13801 gttagaagtt gttctgaaag aattaagaga ggaacgtatt cccgttgtca tctattatca
    13861 cggatggcag acaagtaagg agttagtttt gacgcaagga agaaaaattg cgcagcaggg
    13921 cattcgtgtg atcctgccag atgcgatgaa tcatggggag cgcaaacagc cggtttcttc
    13981 tattccatcc tatacatttt gggatagtat ctacggaaat ctgtttgaat ttgacacact
    14041 tatcaagcat ttagaaaaaa gaggtcttct acatgatcag cttgcagttg gcggggtttc
    14101 gatgggggga atgacaacat gcgccttgtt ggctaaacat cctcatatag tagcgggcgt
    14161 gtgtttgatg ggttcccctg cacctttgga atatggaaaa gaaatcgtaa ggcgcgcatc
    14221 ggaatataat tatgtcgtac caaaagacta ttttgatttg atttcatggg ttaagagcta
    14281 tgatttgtca ttgcagccgg aaaagttagc tggacgtcct ctgttctttt ggcatggaca
    14341 agctgacgaa aaaatccctt atatacaaac ggaacgattt gtagaaaaaa atcggcataa
    14401 gtcttacgga aaagaaattg tttttcgttc ctcaaaaaca cagcgacata tggtacaaat
    14461 accactaatg gaagaagctt ccactttttt agcaaaaaat ttgataaaaa agtataaata
    14521 attgaaacgg aaaatcactc atgacgatag aggattttcc gttttttatt ttgggctata
    14581 ataaactctg ttaggaaaat ttggtataat tgatagtaag aatgacaaca tgttagaaag
    14641 gaagagagca tgcccacttt agcagatgtt gcaaaacgtg ccaatgtttc aaaaatgacg
    14701 gtctctcgag tcatcaatca tccggaacag gtgactgacg aattgaaaga gttagttttc
    14761 tcagcaatgg ctgaactgga ttaccgtcca aatattgctg caaaagcact tgtcacgaat
    14821 cggtcgcaga tcatcaaatt atttatactg gaagaaatcg acacaactga gccctattac
    14881 atgaatttgc tgatgggaat cgctaaacgg atcggtaaag cgcattattc tctccaatta
    14941 gttacaaatg atgccttcga cgtcggttct tgtgatggat acatcatcac aggtgtcaga
    15001 aaaaaagact tcgattggat cgaccgtttg gaaaaaccag ttgtcttgtt tggggaaaat
    15061 tctgaaggat atgattatgt agacagcgat aatgaatatg gtacagcaaa agcaacgcaa
    15121 tatgccttag aaagagatta tcaaacgatt atttatatcg gtatcgaagt ggacgagcct
    15181 tttgaaattt caagggaaac tggttattta tctgtgatga aggaagttga tcttcctagt
    15241 aaaatcttgc ggtttccaaa tcattcgaca gaagtagaaa gatatatgac agaaaactgg
    15301 gcagatttta cagataaaac ttgttttgta tgtagttcag atcggctagc actaggagca
    15361 gtaagaggga ttataaatgc tggaggacac ttgcccgaag aatttggtgt gattggattt
    15421 gatggggtat ttttagacca aatcagttca cctaaattga caacgatcaa gcaagatatt
    15481 atacgtatgg gtgaagtatg tggagaaatg ttgttaaaaa aaatagaaga aaaaggggcg
    15541 agtcaaggtt atcgtcgttt ttttcctgaa ctagttatca gagagacaac gaattaagtc
    15601 ttattactat atatatattt atgaaattca tcgctatttt cttaaaataa tcagcgcatt
    15661 gctactgaaa acaatgaatc tgtgctatta ttgagaaaag ttccattttt gagaaggatg
    15721 gtttgaatga aagaaatcag acgaaaacat ttccgttttc ctgcgtacga tgatgagtta
    15781 ggcgtaaaat taaccaacga caagaagcga gtattatttg acggacaaga agatcttttg
    15841 actgaacaga atcagtcccc gtttgaacag atgaaagaat ttcatttcac gaacacgaac
    15901 accgagaaaa tccgtcgcaa gcgtcgtgca acaaatggat tgaagtcagc tccgcgtaag
    15961 gaaaatttgg aaaagcataa aggaaaatta ccggattata ccggccatta ccaatcagaa
    16021 atcacatcga caggacgaaa aaaacttttt ggtgattcct ctcgttctgt cagacaaagt
    16081 gaaacaagga cagagtccaa gcatactaca cgaaacgcat ctgttgacac gaaggtgcgg
    16141 gagcgttctt attttgttcc taaatatgta cccgcatcga ttatcccaga ccctagagaa
    16201 agcaaaattt ctgaggatca tttaatcgaa tcgatgaaaa aaacggatga ctcttatctg
    16261 ttgttcgata cagaaccgac gccgtatcaa gaaaaaagaa atggtgagcc gtctgtacga
    16321 acattcaatc gaacaaaaac gttagaggaa acaaagcagt cagaagaaaa aaaatcgaaa
    16381 aaaagccatg gtatcttaga acgctcatta caaggattga tcgatgatca aggaaactct
    16441 ttgggagaaa atagctattt taaataagtg atatacaaat ttatattcgg ctacagttgg
    16501 aaaggaaacg ctgcggcgtt tccttatttt atactctatc cgaaagttta tatcgtatcc
    16561 tcaaattttt ttgagtttaa gcgaattttt tctcccaata agtaagaaaa taatggcaaa
    16621 ataaaaaaac aaactatttt cgcagatcgt ttgcaaaaat agtttatttt tttataaaga
    16681 agattttact gaataatatc attttagttt acataatgat atttctgtaa attaaataaa
    16741 gtagtgaaaa ataagaatca gtgctctaac tgttcaagag gatcaagtgg ttcaaatgtt
    16801 tctgtagtct gttttgcttc caattggggc aaaacagatc caatttccag atacttcact
    16861 ttattcaatg tataagatag aatagaacag ctaagtaatg tatacagaaa atgtgtgaga
    16921 tccaaataaa gcaaggagac aactaaaata ccaaaagtaa tcaagaaaag acttttgcca
    16981 atcttaatat gaaaatattt ttcaatggct tgataaatga tatctgttcc gcctgtgctt
    17041 ccgccgaatc gaaagacgag accgcaacca atgccagaaa gaatacctgt catcaaacta
    17101 ttgatcagta gactatctac agcaaaatgt atatgaaggc tctcccataa atgtaaaaag
    17161 aaaactagcg caaatgttcc gacgatcgtc cggagaaaag cgtgttttcc aaaaagaaac
    17221 aatgagataa gcaataaagg taaattaaaa agcagtgaag tgacagaagg agcgaatcca
    17281 aaaagattat gcaaaagcaa agcaatacca gtaaccccac catctgccag cttagatgga
    17341 atattgattc ctgtcacagc taatccgtag attcctgcgc ctaaaatgat tccgcacaat
    17401 tctgtaaata aatttaattt tttcatttct agcctctttt cttttgaaaa ttttcagcaa
    17461 cttctttatt atactgactt atactcttac ttcaagagga aaatgaaaaa aaattatttt
    17521 tggctgtttc tttttattta tcaaataagg agtggaaaaa tgcgagcagc agacttattg
    17581 acaattctta caaaatcacc caaaaaaaca gagtatcaag gagttttttt ggctcaagaa
    17641 caaaaactgg tgcctgtgac aatggtccag ataaataaag caaatcaatt tatcttttta
    17701 tttgaacacg gcaaagcacc acttgctatg aaagacatct ttcttttttt gatgaagaac
    17761 cgtgagaaag ctgtttatta tcagtcaaaa gaagaactca ttcctcttta tggagtgaaa
    17821 gagatagaaa ataaagtggt gatataagta aaaataagaa aacaagacgt ttatgatgtc
    17881 aaaacaacca ttttttacat ttttggcaaa aaagtgtcat gatacagtat aatattcgtt
    17941 gaacaggcca ataaaggtgt tctcccccac gagatttcta ctttattggc tgtttctttt
    18001 tattaaaata aaagttgtgt gtgtaaaaaa gatatagctg attccaagtg acaatttcgt
    18061 atagattttt atggtattcg tagtgaaaaa acgagaacca aaaagttgat ccgactttgt
    18121 tgcttggatt ctttttttgt cagcatattt agaggtattt ttttcttttt tttgttcgtg
    18181 ctgtaaggtt aaggcaagac aagttagttg ggaaaaagga aagaaatgtt tatacttaaa
    18241 gaataacaga aaggaaggtc gcatgaataa ttttatacaa acattaagtg aaagaaaagg
    18301 cgagttgctg gaagctgcat ttcaacatct gtccatttct ctcatttctt tgctgattgc
    18361 agcactgatt gctattcctt tagcgatttg ggcagccaat cataaaaaaa tggcagaagt
    18421 cttattgcag atcacgggtg tgctccaaac gattccttca cttgccttat taggtttact
    18481 tatcccattt gtagggatcg gaactgttcc agcattgatt gcacttgtta tttacgcttt
    18541 gcttccgatt ttccaaaaca cgtatattgg tctagctgaa attgacccgt ctattgaaga
    18601 agcagcggta gcatttggta tgtccagaat gagacgcttg ctgaaagtag agcttcccat
    18661 cgcattacct gtcattatct caggtatccg aactgcctta gttttaatca tcggtacggc
    18721 tactttggca gcattgatcg gagcaggtgg attagggaca tttattttgt taggtattga
    18781 ccgaaataca cctgttttga cattgattgg tgcgatcagt tctgccttgc ttgcaattat
    18841 attcagcgga ctgattcgct ggttgcagca taagaaacct cgatattcca tcattacttt
    18901 agcagcagtg gtgtgtttat ttggcggcgt ttctttatat cagtctgcct tgtttaaaaa
    18961 tgaaaccatc acgattgctg gaaaattagg agcggaacct gaaatcctga tccaaatgta
    19021 taaagaattg attgaagaca acacaaaaac agaagttgaa ttaaaaccga attttggcaa
    19081 gacgagtttt ttgttcaatg cactggatca aggtcaaatc gatatctatc ctgagttcac
    19141 aggtactgtc ctagaaagct tggtgaaggt acctgaagca atgaaaagtg ctgatttgac
    19201 aaaagaaaaa acatatgacg aagcagaaga attattgaat aagcaattcg atatgacatt
    19261 attaaaacca atggcttacc aaaatacgta tgccttggca gtcaagagat cttttgcgaa
    19321 cgaacatcaa cttaaaaaga tttccgattt ggcagctatc tctgatcaga tcaaagcggg
    19381 attcacactg gaatttattg atcgttcaga tggatataaa ggaatccaag aagcatatgg
    19441 cttgaatttt tcaagtgtac aaagcatgga gccaagtttg cgttaccaag caatcaataa
    19501 tggagatgtc aatattgtgg atgcctattc cacagatagc cagctcaagg agtacgatct
    19561 agtgactcta gaagatgatc gagggttatt cccagcttat caaggcgcac cgctgatgaa
    19621 aaaagatttt gctaaagaac atcctgaaat cgttaaagca ctgaataaat taagcggaaa
    19681 aataacagag gatcaaatga ttgatatgaa ttaccaagtc aatgtcgaaa agaaaaagcc
    19741 gacagaagta gcacgaatct tcctgaaaaa tgaaggatta gtaaaggagg aagatcagtg
    19801 actaaattaa tcgagttcaa acatgtgcaa aaaaagtatg atggaaagta tgtcatcgat
    19861 gacctaaatc tggcaatcaa aaaaggagaa atctttgttt tggttggtcc ttccggtagt
    19921 ggaaaaacaa ctactttgaa aatgatcaat ggattatcta aaccatcagc aggagacatc
    19981 tacttcaaag gaaaatcgtt aaatgaatat aatctgcaga aaatgcggtg gaatatggga
    20041 tatgtgctgc agcaaatcgc tttgttcccg accatgacag tcaagcaaaa tattgaagtc
    20101 atccctgaaa tgttaggttg ggaaaagcag aaaagagcag accgtgtaga tgaacttctt
    20161 caaaaagttg gcttatctcc tgatatttat cgagatcgta tgcctagaga gttgtctgga
    20221 ggagaacagc aacggatcgg gatcatccga gctattgctg caagcccaga tgtgattttg
    20281 atggacgagc catttagcgc attagatccg atttcaagaa actcattaca agaattggtt
    20341 ttgtccttac acgaagaatt gggcacgacc atcgttttcg ttacgcacaa tatggaagaa
    20401 gcaatcaagc taggtgatcg tattgcattt atgaaggatg gagaaattat ccaatgtgac
    20461 acaccagagc agttattgat gaatcctaaa aacgactacg ttcggcattt ctttgatgaa
    20521 ccgaaacaga cgaaagagtg gcgagtagaa gatttagtcg tcaatggata tttcttaaat
    20581 gaaataccag aaaatgctcg tcaacaagtt tgctttgata cgcctatgaa agaagtatat
    20641 tcgcttcttt cggtgtatcc aagcattgtg atagtagaaa agcaaagaag tattgggtcg
    20701 ctgacaagta aagaaatctt tgctttttta agtcgagagg aggaaggaaa tgaaaacata
    20761 tgatgcaatc atcatcggtt caggtgtgag cggcttaagt gctgcttatg gattgaaaga
    20821 agcaggtaaa acagtactag tggtcgaaga agatctatgg ggcgggactt gtcctaaccg
    20881 tggatgtgat cctaaaaaag tcttgttaag tgcagtagag gcacgtaatc gggtaaaaca
    20941 attgagtgga aaaggtttta acgagatccc aactgccaac tgggaagaac ttcaaaaatt
    21001 caaacgaaca tttacggatc cagtcccaga aagccgaaaa aaacaattag cagaagctga
    21061 aatcgatcat ctttcaggaa ccgctcgttt tttggatgat tcatctattg aagtcaacga
    21121 agaagtcttc catgcggatt acttagtttt ggcaaccggg caaagaccta cgatcttacc
    21181 agtggaggga aaggaatact tgaaaactag tgcagacttt ttatcattgc ctgtactgcc
    21241 taaagaaatc atttttatcg gtggtggtta tattgctttt gagctagcta cgattgccaa
    21301 tgctgcaggg agcaaagtaa ccattgtcca tcataatcaa cggccattaa aagaatttga
    21361 ggcgtctttg gtagaggaag ccgtccatca aatggaagca tctggcattc agtttgcttt
    21421 tggtgttgaa acccaaaaga tcatttcaga aggtactcgc tatcgtttag tcggaaaaga
    21481 gacggaatta gtagcagata tgattttttg tgcgactggg agacagccga atacagaatc
    21541 tttagcactt gagcaagcga atatcgtctt tgataaacac ggaattgcag tcaatgatta
    21601 tctgcaaacg agcaatccaa aaatttttgc gtgtggagat attgtttcaa ggaaaacccc
    21661 aaaattgaca ccagtcgcca cttttgaagg aaattatgta gctaagcgga taacggatgc
    21721 aacaagcgaa cctatcaaat atccgattat acctacgatc gtctacgcca gtcctaaact
    21781 tgctgaagta ggagttacaa aaagtcacgc ctcttcgtca gatcaagtgg tagagatgga
    21841 tcttaccagt tggttcacct atcatcgtgt caatgaacca gttgctaagg ctgaattgac
    21901 ctttgaccag caaaattatt tgattggtgc tgcagtgatt agcgagcaag cagacgaatt
    21961 gatcgatgat ttgacactcg tcatcaatca aaaattgact aaaaaagagt tggatagcta
    22021 tatcatgggg tatccgacat tggcaagtga tctctcctat ttattgaaat aatcagcatg
    22081 ataactaaag cgcttgttgc tttttccttc ttgtgctaca ctttaaaaaa tgaatacctg
    22141 tttctgggga tgtcgtagac gacatgagag taagttgtga acttagaccc attgaacctg
    22201 tcagttaata ctggtgaagg gagaaacata gcagacgctt gaagcgggtt actatgtcgt
    22261 gcccatttca agcgtttttt gttattcata ttagaagaaa ggaggtaaca aaatgaagaa
    22321 aaatctttat ccagcagtca gtatggcatt cattttaatt atttggcaga ttgttgtcat
    22381 agtttggaaa atacctgcct ttattttacc cggacctgct gctgtatttt ctgcattagc
    22441 ggcagatgca caagtattac tttcccattc tgtcacgaca ttaaatgaag cagtgcttgg
    22501 tttggtaata gctagcgttc tttcttttat tactgccttg gcaatggatt attggaagtt
    22561 tttagaaatg tctttttatc cgttactagt gatttcacaa atgttgccaa tcatggtgtt
    22621 agggccatta cttaccctat ggtttggttt cggtatgctt ccaaaagtga tccttgttgt
    22681 cttgataagc tattttccga tcgtagtttc tttttcggat acattgagga aagtatcaaa
    22741 agagcaaatc atctttttga aaacgatggg ggcagataca gggaagattt atcgaatata
    22801 taaaatacca gcgggtttat ccggcttctt ttccggttta aaagtggctg ctacttattg
    22861 tgtcagcgga gcagtcgttg gagaatggct aagcgctcaa gcaggcttag ggtattacat
    22921 gatacgcgta aaaaacagct accagatcga taaagttttt gctgcgatca tttgtgtcat
    22981 tctattgagt ttattgctga atggcgcttg ttcattattg aaaaaagggt attatcgtat
    23041 gctttatatt ttttaagaga aggggatcaa atgaaaaaat tatggctttt attaccgcta
    23101 ctgttgcttt tatccgcttg tggcactgca aaagaaacaa gtagcaaaca agaaataaag
    23161 gatttgaaaa aagtgacact tgttttggat tatgtaccga atactaatca tactggcatc
    23221 tacctagcaa aagaaaaagg ctattataaa gaggctggtt taaatgtcca aatcatcgaa
    23281 ccaggagata attcgacaag tattggtcta gtaggtgcgg acaaagcaca atttggtgta
    23341 agttatcaag aagatgtcac ttatgctcac gcagatggac agaatatacc agtcaaagca
    23401 attgctacag tgatcaaaca taatacttct ggattcgcca ccctatcaga cagtaacatc
    23461 cattcaccaa aagattttga aggaaaaaca tatgcaggtt ggcaaagtcc aagtgaagaa
    23521 gctgtcttaa aagctgtgat ggaaaaagac ggcggggact tttcaaaact gacaatggta
    23581 ggaagcaatg gagaagggcc agaaagctta ggaaaatcct cagatatcca atggtacttt
    23641 gaaggttggg atatgatcaa agcaaaagaa gcgggtattg aactaaacta tatcccattg
    23701 aaagaattag atgaacggtt agattactat actccggtaa ttattacgaa tgatcaactg
    23761 atcaaaagtg atccagaatt ggtacagtct tttatggatg ccacgaaaaa aggctatcag
    23821 gaagctatta aggatccaaa tgacagtgct aaactgttgc aaaaatatgc aaaagaaaat
    23881 gatcggacgt ttttagaaga atcacaagca ttcttgtcaa aaaattatac ggatgatcct
    23941 gagaattggg gattgatgga agaaaaagtt tggcgcaatt atacagcttt tatgcaggaa
    24001 aacggattga tcaagcaaga tgtaccttcg caagaactat tcactaatca gtttataaaa
    24061 taggagtgat agatatgtca atccaaatca gccacttgaa tgtagtcatt gaaaacctga
    24121 aaatattaga agacatccat ttcactatcc ctaaagatac ctttacatcg attgtcgcgc
    24181 caagcggagc cggtaagtca acattgctga aaactttaac aggagtccag cctatgactt
    24241 ctggaacgat caaagtagac gatcaaaaag taactggtct ccatacagca tttagttata
    24301 tgccgcaaga agatatgtta cttccttggc tgagcgtcta tcaaaacgtt acgttatatc
    24361 aaaaaatcaa tcatctaaca atcaatgaag aacaagtaag ggattatctg gatatctttg
    24421 ggttaaacgg ctatgaacat tttttgccgg aacaattatc tggcgggatg aagcagcgaa
    24481 cggccttgtt acgaacaatc atgaatcctt cttcttactt gcttcttgat gaaccatttg
    24541 gagcgttaga tgctatgacc agagggcaga tgcaagactg gatgttgaag ctgcctaaaa
    24601 aagcaaagcg gactacttta cttgtgacgc atgatatcga agaagcaatt tatttatcag
    24661 acaggattct tgtgctttcc gcccgtccgg cacatgtgat tgctgagatt caagtgcctg
    24721 aaaaacgacg gtcacgtgaa tggctactgc agcaatcaga gttgaagcaa acgatttatc
    24781 agttattggc aggtgaatta gatgttaagt gatgctcatt gtcatttaga tgggagtcag
    24841 agtttagcac tccttcagca ggaacacacg attttgacga tcatcaattg tgattcgcca
    24901 gaagaatgga aggaaaacag acagcttgca gcaagtaaga ctcaagcctt aagttacggt
    24961 atccatcctt ggaaagcaga tagctatacg tttgaacaag ttgagccttt tttgaaaaaa
    25021 gcaaggatca tcggtgaaat agggttagat aatatttgga cgaatgtacc gatgactaca
    25081 caaaaaaaag tatttgagcg acagcttgct tttgcagcca taaatgagaa acctgttgta
    25141 ctgcacacaa aaggatgcga aaaagagatc ttaaattata tccaagctta ccctaatcac
    25201 tatttgatcc attggtattc ttctttggac tatcaacaag actatattga tttaggctgt
    25261 tatttcagca ttggtcttga tttgaaaaag aatccagcag tctggcaact agctaaagca
    25321 gtcccaatcg accacttact tattgaaacg gatggactac atgcagcaga gtgggcttta
    25381 ggggggattt tttcagaaaa agattatgtc tcactgcttg aagaacagtt aaagacaatc
    25441 gctgagatca aagagctatc agttgaagaa gttaaaaaaa atacttatca aaacttggaa
    25501 cgtttcatta gattaggtaa ataaaaaaga gatgtgacac aactagtgtc gcacctcttt
    25561 ttggctttct ttgtataaaa gtaaactgtt tgattaataa atgaatctta gtaccaaccg
    25621 tttgcttccc agaatgcttt cgccgcttcc caagaaccat aacgtgaagt aacatattgt
    25681 tctgctactc tttcttggtt tgcagcagag tagtcaccat ttaagtaaga agaatctaat
    25741 tggtaacgtc cgatgtaacg tccgttcgtt gctgtgtaag aaccgcttga ttctttttgt
    25801 gcgatccatt cttttgcaga gcttgtgctt gctggagtag cagcagtttc tgttacagca
    25861 ggagcaggtt gtgtttcagc aacaggcgct gcttgttttt ccgtttgaac cgtttcttgt
    25921 acaacaggtt gttcagcttg gactggtgct tcttgaacgg ctgcttgagg ttcagcagct
    25981 gcttgtgcag agccttctgt tgggattgtt aattgttgtc ctgagtaaat caggttaata
    26041 tcagaaattg aatttgattc tgcaatggca ttgatcaagg agttatcacc aacgtatttt
    26101 tgagaaatcg ttgatagagt atcacctgat tgaacggtat aagcttcgtc cgcatgagca
    26161 gtcgttccca tgaagaatgc agcgccggca gccaaagttg ttccaaaaag taaagtttta
    26221 agtgatgtca tgaaaaatct cctttattcg ttaaaaagtt ttatttgttg tgttcaacga
    26281 ggaatacttt aacacgtgaa aatatttcat aggtaaaaga agcatgacaa tttatgacaa
    26341 atccgcgttt tttgtaataa atacagtaat ctatgaaatg aaaagggtta cgtttaataa
    26401 aacttgcttt tttgtttttg ttcaccataa atatttattt aagaaagtat taacctgcat
    26461 ttttctctat aaaaaagatt ttttaaatag ataaaaaagg aggattaaat gagtatttga
    26521 tagtatttat attaaaatta catatgtaat ttaaaaacgc ttgacattgt gtttgagatc
    26581 acttactttt agcatgtaaa agtattggat taaggagcta tgcaaatgaa aaagaaattt
    26641 attactggtg ggattgtcgt tgcatttcta tgtctaattg gctacacagg cacgcggtac
    26701 gcaaatgaaa ttattttgtg gggtggagag acagatattg atacaatcaa tgagaatctg
    26761 acacagcttg atcatacatt gacagataaa gagcaagcga ttacagatct taccgctcga
    26821 ctagcacaaa aagaacagac attgcaagat tcaaaggcag atgtccaaga ataccaaaca
    26881 aaagtaaatg aattagaaaa ccaaaaaaat caatcggcag cagaaaaaca aaacttagaa
    26941 agtcaattag tcagcaagga tgcacaacta caaagcaaac aaaatgaaat caatgtcaaa
    27001 ctagatgaga tcaaccaaaa aaatgatgaa atcaatcatc tgaatgcaga ttggacagca
    27061 agactacaag aagcacaagc aaaactttca gaattacaaa atactgtaaa tggtttgaat
    27121 caacaaatcg caacactgac acaagaaaaa acaaatgtag aaatcagtta acagatacac
    27181 aaaagaaatt agacgaagca actgctgaaa actcaagctt gaaacaatat attcaaaagt
    27241 tagaaaaagc aaaagatgaa gtggaagata cagctgataa atctcagcaa attgttgaag
    27301 aacatttgcg taaataatct ttcttaacaa gtaaacctaa attagtaaag aagcaacagt
    27361 aatctatact gctgcctctt ttttttagta catgtccttc atcttcgcag gaagtgccaa
    27421 tatgatttta agaaaggtaa tagacaaaaa gtcaaaaaga taaaacagag tttcttcttt
    27481 acaaagggaa tgtatgttcg tataatggta ttgaggtgaa ggttatggag aaaaaatatg
    27541 gaacagtaga taagatccgt actttgcaag ttagtgccag accgttgatc cgtttcagtt
    27601 taaatggggt caattgtttg attgcttccc atagtttgaa cttcctagct gaagtagacg
    27661 aagggatgaa gttagtcgtt acaggttatt ataataatag aaagcaattt gttgtgagat
    27721 cctatcatgt gttagggaaa cccaaaattg tggtagaata tgagaaaagt ctatacccaa
    27781 gaaaaaaggt ccgacaagat gaaagaataa actagaaaac aagcggctga gacaaaaatg
    27841 tcctagccgc ttgttttgga aagatggatg cagacgatgg gatttgaacc cacacgagca
    27901 tacgctcaca agaacctcaa tctatatata actacatgta tttaagtatt tgtgatgaat
    27961 cactaaactt tccaaactca tttgagggat attgcttaaa gattgaacag atcaattcga
    28021 agccctatta gtattcgctc aatgggggga tcagaggcca taaaaagaga ctagtcatta
    28081 ctagtctcag gtagtggaat tgtaggattt taaacgttcc tggagagtac cggtatgtaa
    28141 ctcgaagagg tgattatcat agtcgtaaaa gtaaattgaa gaagcctcgc ctttcacacg
    28201 agaacgtcct ggttcgacag ttaaacctaa catttggatt tttgagacaa acgaatctat
    28261 atcttgttcg tcaattttaa aagcaatatg attgtatgtc tttggcagtt tattcgacga
    28321 attctgcatt actgcaatcc ataggtcctt aactaagaaa aatttttctg gatataatga
    28381 aaattttttt gttgactatc gtagatttct tttgcatcaa ataaggtatt taacaattaa
    28441 gtatttaaaa gataactttt aagttatctt taagtaatgc ttaaagctat gttatactct
    28501 attaggaaat ataagaagga gtataaaaat gaacaaacat aatagaaaaa taacgaataa
    28561 caaagaactg atcttgttac taatagggat ttggggtatc tttttactct ttaatatgta
    28621 tatgccgact atgagagcgg atgacgtagt ttatgcaagt agattagatg aacttggcta
    28681 tttgggtgct tcgatagaac attataagac atggagttca agaattatta tagaactatt
    28741 cttaatgttc ttttctaaac actttatgct atggaaatta ttaaattcta cgattatgtt
    28801 aggaattgta gtattacttt gcaagtatg
//
LOCUS       DAFBSV010000030        27635 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.031, whole genome shotgun sequence.
ACCESSION   DAFBSV010000030 DAFBSV010000000
VERSION     DAFBSV010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.031"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            121..768
                     /locus_tag="LLB18_001224"
     CDS             121..768
                     /locus_tag="LLB18_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBK5244236.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            852..1796
                     /locus_tag="LLB18_001225"
     CDS             852..1796
                     /locus_tag="LLB18_001225"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HBK5244237.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            1931..3382
                     /locus_tag="LLB18_001226"
     CDS             1931..3382
                     /locus_tag="LLB18_001226"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HBK5244238.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            3403..4239
                     /locus_tag="LLB18_001227"
     CDS             3403..4239
                     /locus_tag="LLB18_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBK5244239.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            4239..4898
                     /locus_tag="LLB18_001228"
     CDS             4239..4898
                     /locus_tag="LLB18_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBK5244240.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            5024..5713
                     /locus_tag="LLB18_001229"
     CDS             5024..5713
                     /locus_tag="LLB18_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244241.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            5719..6675
                     /locus_tag="LLB18_001230"
     CDS             5719..6675
                     /locus_tag="LLB18_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HBK5244242.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            6719..7231
                     /locus_tag="LLB18_001231"
     CDS             6719..7231
                     /locus_tag="LLB18_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5244243.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(7487..8035)
                     /locus_tag="LLB18_001232"
     CDS             complement(7487..8035)
                     /locus_tag="LLB18_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK5244244.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(8124..9305)
                     /locus_tag="LLB18_001233"
     CDS             complement(8124..9305)
                     /locus_tag="LLB18_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HBK5244245.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(9541..11049)
                     /locus_tag="LLB18_001234"
     CDS             complement(9541..11049)
                     /locus_tag="LLB18_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBK5244246.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            11208..11399
                     /locus_tag="LLB18_001235"
     CDS             11208..11399
                     /locus_tag="LLB18_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244247.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            11602..12519
                     /locus_tag="LLB18_001236"
     CDS             11602..12519
                     /locus_tag="LLB18_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HBK5244248.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            12512..13585
                     /locus_tag="LLB18_001237"
     CDS             12512..13585
                     /locus_tag="LLB18_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244249.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            13733..14251
                     /locus_tag="LLB18_001238"
     CDS             13733..14251
                     /locus_tag="LLB18_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244250.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            14232..14624
                     /locus_tag="LLB18_001239"
     CDS             14232..14624
                     /locus_tag="LLB18_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HBK5244251.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            14700..15635
                     /locus_tag="LLB18_001240"
     CDS             14700..15635
                     /locus_tag="LLB18_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HBK5244252.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            15768..16547
                     /locus_tag="LLB18_001241"
     CDS             15768..16547
                     /locus_tag="LLB18_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBK5244253.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            16540..16857
                     /locus_tag="LLB18_001242"
     CDS             16540..16857
                     /locus_tag="LLB18_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBK5244254.1"
                     /translation="MTKLYLLLLVVCLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            17101..18711
                     /locus_tag="LLB18_001243"
     CDS             17101..18711
                     /locus_tag="LLB18_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBK5244255.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            18868..19716
                     /locus_tag="LLB18_001244"
     CDS             18868..19716
                     /locus_tag="LLB18_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBK5244256.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            19947..20426
                     /locus_tag="LLB18_001245"
     CDS             19947..20426
                     /locus_tag="LLB18_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244257.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            20459..22687
                     /locus_tag="LLB18_001246"
     CDS             20459..22687
                     /locus_tag="LLB18_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK5244258.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            22816..24459
                     /locus_tag="LLB18_001247"
     CDS             22816..24459
                     /locus_tag="LLB18_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBK5244259.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKINK"
     gene            complement(24532..25077)
                     /locus_tag="LLB18_001248"
     CDS             complement(24532..25077)
                     /locus_tag="LLB18_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HBK5244260.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(25100..25585)
                     /locus_tag="LLB18_001249"
     CDS             complement(25100..25585)
                     /locus_tag="LLB18_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBK5244261.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(25575..26387)
                     /locus_tag="LLB18_001250"
     CDS             complement(25575..26387)
                     /locus_tag="LLB18_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HBK5244262.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(26526..>27635)
                     /locus_tag="LLB18_001251"
     CDS             complement(26526..>27635)
                     /locus_tag="LLB18_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBK5244263.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT         9048 a         5027 c         5526 g         8034 t
ORIGIN      
        1 tctttttctt tatattttca taataaaagt ttggttcttt aatttttaaa catgacagaa
       61 aattttttct tcgttatact tgtaatagaa tactatttta taacaaaggg gatcgaatca
      121 atgaaaaaaa ctgttattta tactagttta tttgcagctt tgtttttagc tgcttgtcaa
      181 tcaaatacca atcaaggcac atctgggaat acgtcttcca gtagcgaaca gcgctcttca
      241 caggtatcgg actcctcaac aaaagcaagc acatcttcgt ctagccagac aaaaagttct
      301 agtgaagcaa gtactcagtc agatatcaaa gtgtctgcag ctcgtgcgat cgaattgttc
      361 caagataaat acccagatac tgcaattact agtttggaat tagatagtga ttggggatct
      421 tacttctaca agatagaagg tgtcgatgat caaaaagaat acgaagcaag aattgatgct
      481 caaaatgaaa aaatggagac agagaatcca gaaactctag atcgagatga acaaaatggt
      541 caaaagaaaa aagaagatgg tctggatgtt gataaattga tcacgattga ggaagcagca
      601 aaaatcgccg tcgacaaagt aggaagcggt acggcaacag attgggattt ggataaagat
      661 ttaggtacta cttattggga agtcaaagta aaagacggca atcaaagtac atcagtcaag
      721 atcaatagcc aaacaggcga agtactgtca actgaacaag atgattaaga atttcttcgg
      781 aaaacaagag ttgatttttc ttttagtcat gatacactag acaaaataac ttgtttgaag
      841 gagcgattta cttgagttta gaaacgacct ttgccaatca tatctttgcc aatcctttga
      901 tgaatgcatc tggtgtccac tgcatgacta cccaggaatt agatgaactg gctcattcag
      961 aagcaggagc atttatcact aagagctgta cgatcaatga acgaaaagga aatcccgaac
     1021 cacgctattt tgatgttcct ttagggagta tcaattctat gggacttcca aacttaggtt
     1081 tttcttatta tctagagtat gctcttgcgt atgaaaaagt gcaggaaaac caaaatcaac
     1141 cgttattttt ttccattgcc gggatgagtg tccaggaaaa cttggaaatg cttgagaaaa
     1201 tagaaaaaag tgggtttaat gggatcactg aattaaattt atcttgtccc aatgtgcctg
     1261 gaaaaccaca actagcttac gattttgagg ccacttatga aacactgaaa gaagtattca
     1321 gcatcttttc taagccgcta ggaatcaaat tgcctcctta ttttgatttt gctcattttg
     1381 atcagatggc tgatatcttg aatcagtttc cattgaccta tgtcaatgct atcaacagtg
     1441 tgggcaatgg tttgtatatc gatacagaac aagaagcagt agtcatcaaa ccaaaagaag
     1501 ggttcggcgg cattggcgga gagtatatca agccgactgc tttggcgaat gttcgcgctt
     1561 tttatacacg tttgaaacca gaaatccaaa tcattggtac aggtgggatt cggacaggac
     1621 aagatgcatt tgaacatctg ctatgtggcg caagcatgtt acagattggt accgagcttc
     1681 ataaagaagg gccggaaatt ttttctagaa tcataaaaga attaacgcag attatgtcag
     1741 aaaaaggata tacgtcaatt gacgaattta aaggcaaatt acgcaccatt tcatagcaaa
     1801 gagacgaagg tcatgattga tcttcgtctt tttttataaa aaacactcgt ctgttcattc
     1861 ctgtgcaagc gtactcattg tatgttagac gaacttgtgg gaaaataaca gaggcaaaaa
     1921 ggaggataat atgaatgatg caacagaatt agcaaaagag cttaaagaaa aagaatttag
     1981 ttttcaagaa ctagttacgg atatacagaa aaaaataaag aagcaaaatc atgaattgaa
     2041 tgcgtttgtc gcgcttgaac cattcgagag taattcccac gagctattga ttccccagtc
     2101 agaaaaaggg ccattggctg gtatcccatt tcctttaaaa atgctcggtc aagaaaaaaa
     2161 gggatggcta gctacttcag gatctcgttt atttgaaaca caccgagctt ctcatacatc
     2221 taattatgtg cggcaagcag aagcgatagg tctagttcct tttggacaaa ccaatgcgcc
     2281 agagtttggt ttcaaaaata ttacagaccc agtcatctat ggcccagcaa gaaacccttg
     2341 gaaccttgaa tgtacaccgg gcggatcaag tggaggagct gctgctgcag tttcatcagg
     2401 aatcgttcct ttagctggtg ctagtgatgg cggtggttct attagaatac ccgcttcgtt
     2461 ttgcggattg attgggctga aaccttcgcg agggacgatg ccagttggtc catatgcttg
     2521 gagaggatgg caaggagctg ctattgattt cggcttgaca gtttctatga gagacacgga
     2581 ggctttattt tatgggatga gaagtatcca ttccggtgcg ccatatcaag tatcgccagt
     2641 tgagtggcaa acacatccaa gaaaaaaacg gttgaagata gctttttgtg ttgattcacc
     2701 gatccactca cagattagtg aagaggcagt acttgctgta aaaaaagctg tagatttcct
     2761 tggaaaagaa gggcatgatt tgacagagat tccttaccca ctagatggtc gtaaactgat
     2821 cacgtcttat tatcagatga atggcgcaga aacagcagca atgatccgct cgattgaaac
     2881 aggcatccag cgagctgtca gaaaagaaga acttgaaccc atttcttgga ctttgttcca
     2941 atatggtcag aagctctctg ccgctactta catcgattct ctgcatgtat gggatgaagc
     3001 agcaattgtc atggaaaacc tacatcaaga atacgatcta ttcctttcac caacgactgc
     3061 atttaccgcc cctaaaatca gcgaagattt gcaaagtgat gcgataagag cacagatgga
     3121 acacatcagt gattgttctg aagtagaagg tttagacgtt gtttcttcca tgtttgagga
     3181 gagcttgaag atcacacctt atacacagtt ggctaatctg actggacaac cagcaatcag
     3241 cttgcctact catttgacaa aagaaaacat gcctctagga atccaattta tggctgccag
     3301 aggaagagaa gatttgctat ttcaaatcgg ctatctattt gaagcaaatc atcagttcca
     3361 tttaccaaat ccatggaaat agcagaaaca aggagaagaa gaatgaagaa aaaaagattg
     3421 tttgctctaa taactagtgc cttttttatt ttaagcgctt gcggtacagc tgccgctaat
     3481 caggaagata acagctggag taatgtagaa aaaaagaaag aattagtagt agcgacttct
     3541 ggcacactgt ttcccgcatc ttattataat gatcaaaatg aattagttgg ttatgatgta
     3601 gatttggcaa aagaggtggc taaacggtta aatgtcaaaa tctcctttaa agaatacaac
     3661 gtggatggac aaatcacttc tgtttcaaaa agagaatcag attttgctgc gaacgatttt
     3721 ggtatcacaa aagaaagaga aaaaaaattc tccctttcag agactttcaa atattcattt
     3781 gacagtatga tcgtacgaaa aaaagatgat tcaggaatcc actcacttga agatcttaaa
     3841 gggaaaaaag cagctggcga acccaatact agctatatgc gtttagcgga aaaacacgga
     3901 gctaaattag tcacatatga caatgccacg aatgatcagt atttaagcga tgtagcaaat
     3961 ggtcgaacag atgttattct aaatgattat tatctgcaga aaatggccgt atctgcttta
     4021 ccagatatcc ctgtaaaaat actggagaac gtttatttca atgaaaacga aagtggtttt
     4081 ttattgaaag aaggaaatga tgctctgaaa aagaaaatcg atggcgtatt aaaagagatg
     4141 aaagaagatg ggacgacaaa gaaaatatct gaaaaatatt ttcaaactga tgtttcagtc
     4201 aaaccgaaag aaacgatggc tgagtcggtg agtgagtgat gtactttcct ctaattgatt
     4261 tttccctcat gtggacttca cttcctttcg tactgcaagg cttggtatac acattaggga
     4321 ttggcttcgt gtcgtttctt ttaggaaatc tggtagggtt gcttttgaca gttttaggtc
     4381 ttttggattg gctgcctctg aatgtattta ttcgttttta tttatcgttc tttagaggca
     4441 ttcccgcact agtcctgctg tttctgttat attttgggtt accttatcaa ttaagtgcct
     4501 taacggcttc agtcatctgc tttacgatta ccagcagtgc atttattggt gaaatctatc
     4561 gaggatcact agcaggcgtt tcttcaggtc agtgggacgc tggtttagct tctggttttt
     4621 ctttctttgg ggtattgaaa tatatcgttt tgccgcaagc ttttcgaatc tcagtaccgg
     4681 cactcagtaa cgtagctatg gatctagtga aaggtacttc gttagcagca acaatcacag
     4741 tgccagaaat atttcaaaaa gcaaagatca taggcggtcg gacattcgat tatttttctc
     4801 tctatatttt agttgcactg atttattggg tcatttgtat cgggatcgaa aaagtgcaac
     4861 agtatttaga aaaacgttct atgcatcagt caatctgaaa aatagaaatg gtgctagcgt
     4921 ggctggcacc atttctattt tttgtttctt gtatattctg cctagtattt taaaaccatt
     4981 tcatgtaaaa tgtaaatcga aaatatgttc ggaggtagaa aacatgaaga ccccgctaac
     5041 catcgaaata gaatcctcgt tataccaata ttgcatcgag caaggcggct tggttgtaga
     5101 agaagtcacg atgcctgatg accaaggaat tgtagatacg cttagctgct tgacaaaatt
     5161 tgatggaagc cgagaatggc gatgctatga gctgaaagtg acaaaagcag attttcgctc
     5221 tacagccaaa ctgtcatttg ttggacatta taattatttt gttttaccaa gtaaactata
     5281 tgaagaagta aaaactgaaa tccctacagg aataggtgtt ttagtgtatc gtccgtacac
     5341 ggttgaagag gagatgcctg cctctggtac atttctgatt gcgaaaaaag cagcaaagaa
     5401 agagcttgct gtaccggaag aagctttgac aaaccgcttc atggcttctt tattcaggga
     5461 agtaagaaaa gcaaagcaaa tggagcgagg cgtaaaatat tttccaacag atcaattgta
     5521 caaagaattg aaaagacgtt cagaaaatca agatccattt tctaacgaac gatattatga
     5581 acggttttta gaggaaatag ctagtcaggc aatcaatgag ttgcaagaag aagttatcgc
     5641 gcttcagcat gattatgaat atttgaggca acaacagcag atccgtcggt tgcctacaga
     5701 gccattggag tgaaaaatat gtactatcct tatttaagag gaaaacaatt tgacctatta
     5761 gcattaaaag aagcactgtc gcgaggattg ctctccaata aaatccaacc agtgatcgaa
     5821 ccagtacgtg attccgctac gcttaaaaat gtgatcgaat tatttcaaaa aaagcaccat
     5881 cgaatcgctg tgatccaaaa tccccaagta ggacaattca aattattcga tcagcatgtg
     5941 cacagttgga cagtcaaaga aaatagctct gtcgtccctg cacagatctt aacgccagaa
     6001 aatctcagtg aagtactgga ttcacctcca gcgtttcttg ttttcgatgg acagcactac
     6061 ccaaaagata cagaggtgtg gaaacagttg gcaggagttg attcgaaatt tttgatacca
     6121 gatactagtc gctttcgcat ctggctgccc gaaaacaaaa ttgtgatccg tgactctttt
     6181 caaacgagaa agcatgttga aagttatgca gataaaacag atgacttttt tagtgatgac
     6241 tatctttttt tccacgcaga cggatatatt ggattttctg atttcacgat cgaaggtagc
     6301 cgttatttcg ataaagggtt ccctagccga gcgcttgcta tccatctaac gtatattgat
     6361 gcttacggca atatacgcgt gaaacatttt gtctctgaca gtaacgactc tgctaaagac
     6421 caagcattga agtttcttga agcaggagat aaaatgaaaa aatggatcat gcgtcaccat
     6481 catcaactct tgattacttc aggaatgatt gaattattgg ctctttacca gcaacaaaaa
     6541 ttccctggac tgggagtgtt gaaaaagtgg tcacttatgc atcatttgga acttattagt
     6601 cacctgctag atcatccaaa agattggctt aaatattatt caaaagttca ggaactatat
     6661 gaagtgatcc aatgattaga taatgtaaat gaaaaaggaa tagaaaagag gaaactggat
     6721 gtatattcgg caaacaagga aagaagaagt agaagaagtg gtagaaatca ttaatgccgc
     6781 agcggatttc attgcttcgc aaggctctcc tcaatggcaa aacgggcaga aaccaacaaa
     6841 agaaacgatt ttgaacgata ttgaaagaaa agaaagctat gtattaatag tggaagatca
     6901 aattgctgga acagctgcat tagtctcaag cgtggatccc gtttacacaa aaatagatgg
     6961 tagttggaaa gaatcaactg gtccttattt atcgattcat cgtgtcgctt tagcagaaag
     7021 tactcgagga aaaaaactag caaaaccgtt cttagaacat ttgttgacga ttgcagccag
     7081 caaaaatatc caagatatcc gtatcgatac ttatccagct aatgaaccga tggaaaagac
     7141 catctattct gctggattca cttatcaagg gatgattgaa tttccttttg aacacggcga
     7201 aagaaaagca tatcaaataa tcatcaattg actataaaat catctgagca aagataaaga
     7261 cattaacact actgaaaaaa acaatcatat gatagccaag aggttgtaac agaagtggcc
     7321 agcttcaaaa aacaagaaag aatttccgaa aatgcttctc aaatttttgt ggaattttag
     7381 cgtattttac gaaatagctg ctttctgaaa ctcccttcat cgagaggtcg tgacatagct
     7441 tttgtcacga cctctcggct tatcctacga gtattattcg atacatttat atcaataatc
     7501 ctttttttat tttatctgca gcttcttgga acgctccatc gtttgacacg actaaaagtg
     7561 aggggatagc tttcaaacgt ttcaactgtg ctaaatcttc tacataaacc gccagtctgg
     7621 ctgaaatctg ttcagatgaa tctccacgtt ttttcaggcg cgattgcaat gtttctttag
     7681 agatcgtaat aaagatagga cggactaccg tcccgaaata ctcatataaa tgccaaaaac
     7741 catttgctgt caaaacggcg taacaatttc ctactgtcag tttcttttta atttctgctt
     7801 tactggaacc atatttatgt tgagcatatt ggtcccactc tgcaaactca tttcccttga
     7861 tcatctgatt gaatgtattg tcagaaacaa aataataatc ctcttgatct ttttccccag
     7921 gtcttggtga tcgattcgtg taagtaatga tcttttgttc cggctgaaaa atagcttctg
     7981 cgagtgaagt ttttccagaa ccagaaggac cgataaatac atagcaataa ttcattgtca
     8041 tttctccttt gatgattgaa caagtgaaaa agctttggaa aatatttcca aagcttttaa
     8101 aagtaacttt gcttttttgt atattatacc agcaagccag tcacaatagc acttaaaaag
     8161 ctgactaaag tcgctgttag caaaattttc aatccgtgtt ttgcgacaag atttcctttt
     8221 tcttcattta atcccttcat cgcaccagaa atgatcccga tagaagagaa gttggcaaat
     8281 gaaacgagga agacagatat aattgctgtt gtacgctcag taaaatggaa attaccattt
     8341 gctaattctg tcatagcaac aaattcattt gtaaccagtt tagtcgccat gatactaccg
     8401 gcatccactg cttctttcca tgggattccg ctgatgaagg caagaggggc aaagatgtaa
     8461 cctaggatct cttggaaagt gatgccgaat atcccgtgga agatagcatt gatcatggca
     8521 atcaaagcaa caaaaccgat aagcatagca gcaaccgtga tcgccacatg gaaaccatca
     8581 agaatgtatt ctcccaacat ttggaaaaat gtctgttctt tgttttcttc aatgatcagc
     8641 tcatcttctt tttcttctaa tacataggga tttacaattg aagccagaat ataaccgcca
     8701 aataagttca aaacaagggc agtgatcaca tatttagaat cgatcagtgc catataagat
     8761 ccgacgatcg acatagaaac tgtagacata gccgatacac tcatggtgaa caaacgtttc
     8821 tcagatagga agggtaattc cttttttatg gaaataaaaa cttccgattg tcctaaaata
     8881 gcagaagcta ctccattata agattccaat ttgcccatcc cgttgatttt acttaatcct
     8941 agaccaacag ctttcataaa taatggaaga atcttgatat agcgtagaat accgataata
     9001 gcagaaataa atacaattgg catcaatacg gaaagaaaga aaggtgcact tcctttattt
     9061 gctacaccgg caaaaacaaa gtcaacacct tgcccagcaa aagcaagaag atgatcaaac
     9121 atttttgcca atacagaaac aaccgctgta ccaaaagttg tacgtaataa tacgaaacca
     9181 agaacaagct gtaaaacgaa catcacaatt agtggtttca atttgattgc ttttttgtta
     9241 ctgctgatca aaaaagcaag ccctaatgtg acaaataaac caataatacc taataaataa
     9301 ctcaaataat cactcctatt ccaaattccg ttttatttta cctgttttgc aaataaaata
     9361 ctaatcttta gtgaaatttt cattactttt ttagagtgaa acgcattcat tttccattag
     9421 aaaataaagc gaacaaaata aaaggtttaa aaagtgtaac gtcttagtaa agtctataaa
     9481 aaaacgaaac tatcgattaa gctaatagtt tcgttttcaa catttataag taaacttttt
     9541 ctattggtaa tatagatttt cggaagggta gacaggtgcg caggtaatat cgattcctag
     9601 ttttttcaat gtttgttcat catttttatt gaccatcaca gtagagtggg cttgtgctcc
     9661 ctcaagttca gctagtttat cataagcaac ttgagcgatt ggattcgtta ctgcactgat
     9721 tgataaagcg atcaagactt cattgatgct tagtgcatcc aaagaggaat gaagtgtctt
     9781 tgatttcaat ccttgtattg tttcaagaac taatggtgac aataaaggaa tgtcatctgc
     9841 gatatgggct aaatgtttta ctgcatttaa gataactgcc gctgacgcat ccatcaatga
     9901 acttgtacgc ccggtaatga tgacttcatc tggtaattcg attgcaatca cagcagaagg
     9961 atcttttgta ggactttgcg cttgaatctt atctgcatag tcatgggcag ggactaccac
    10021 gtttcggtct tcaggacgta aaccgacttc ttccataatc agtttgattc gattaactgc
    10081 ttcttcgtcg atcaatcctt ttttgaagtc gcattctgtt tggaaataac gacggatgat
    10141 ttcttgttta gaggcttctt ggacaacggt atcatccacg atcccaaatc ctacacgatt
    10201 cacacccatg tcagtaggag attgataaac agattcttta ccagtaattt tttcaataat
    10261 acgtttgatt acaggaaatg tctcaacatc ccgattatag ttcacagcta ctttattgta
    10321 ggcatcaaag tggaaggaat cgatcatatt gacatctttt agatcgactg tggctgcttc
    10381 ataagcaatg ttcagcggat gtttcaacgg aacattccat actgggaaag tttcgaactt
    10441 ggagtaacca gctgcatgtc ctttttggct ttcatgatac agttggttca aggaagtagc
    10501 gagctttcca cttcctgggc caggagctgt cactacaacg attggtttag ttgtttcaat
    10561 atactcattt tttccaaaac catcttctga gacgattttt tctacgttga ctggatagtc
    10621 ttcgatttct gagtgtttat agaccttgat gtttcgtctt tctagtttat tgataaagac
    10681 tttcgtggca ggctgtccac tatagcgagt gataacgaca ctgttgatta ataagccata
    10741 accacgtaat tcatcgatta accgcaagat atccatatca taagtaatcc cataatcacc
    10801 acggatctta ttacgttcaa tatctccagc atagacgcaa atcagtattt cagcttgatc
    10861 tttcaatttt tgcagcaatt tgattttcgc atcttcttca aatcctggaa gtacacgttt
    10921 cgcatgcttg tcgtcaacta gcttcccacc aaattctaaa tataatttgt catagtggtt
    10981 cactcgttcc aaaatatacg ctgactgctc ttcaatatat ttttctgaat caaaaccaat
    11041 ttttttcact aggttccctc cttaagtact aaagcatttt ttcatttttt tgaggattcg
    11101 tcaactggaa gagcgaaatt cctcaaaaaa acaaagaaaa tggtttaaac caacttgtct
    11161 agatagttat tcattggtat gatagttttt gataaggaag gtgctacatg aaaaaaagac
    11221 agaaaaagaa aaacgcatat aaacactata tccgttcgat ttttaccggt tatgaaagaa
    11281 tgcttgaaga tcccgaattg gaacaattga cgtttactta tctaaacgaa gaaacgcagc
    11341 taactcgtga tgagcatcag cgcattcatt tcacaacaag agatctgcct agtaaataaa
    11401 aaataagata aaggtcatcg gattcgattc tgtcctatca gatggaaaga ctagttgatc
    11461 gaaaaaaagg ctgtaccaaa ttttggtgca gcctgtttta tggagcattg cccgctcttt
    11521 tttataacaa ttttttacag aaaatggtac tattgaagta ttaataagtg aaaaacagat
    11581 gagtaagagg aggcaagtag tatgaaagag ccagatacaa atgcaaatta tgagccagac
    11641 gaactagagg agacgaatgc ggatcaggat acaggacaag aatcgtcttc tttttacgat
    11701 atcaaagaaa aagcaagcat gaatctttcc caattattag aagacttaca ggcttttgaa
    11761 aaagctgtcc gcgaagaaga tatccctgag atctaccgtt tatacaatgg ccgattgaat
    11821 gaagaattaa aaagaagctc aaatgaaaat cacgagatcg atcaattgct gatgcgtaag
    11881 atccatgatc gttttttaca ggaatttcct tttatggaac aagtagaaaa catctcgcca
    11941 acgatgagct attacaaaat cggcacttat taccatgatc ggcccacggt cggtattgat
    12001 gcaagtctgc cagaaatttt tgttttgcct aagatcgatg aagagtggga gaaatattcc
    12061 caaccggagt caacggacta tgacaaaaaa atcaatgagc tagacgcaaa ggtgatcact
    12121 gctcagacag aaattgaacg tttagatgaa caaataaaag aaatcaatcg acaaatgact
    12181 gatttgaacg acaataaagg attcttgaat cgtaaaaaaa tcgaggaaga aattcaagaa
    12241 ttagagaaga agaagcaagt actatctaat gaaaaattag gctggcttcc ttatattgag
    12301 acgcctgaaa caatccagca gcaaaaagaa gcattgaagc aagaagcaag agcagaccag
    12361 cttcgtgcag ccatcgtaga aaaagaacaa aggcaaatca gacgctattt cggtagcaaa
    12421 gagggattcg gtcaagcaat ccatgaattc ttgatgaatt atcttggcaa tgagaatcct
    12481 aataatcaat ctaatgaagg aggttccgag tatgaatgaa cacgatgaag cagaatggac
    12541 aaaaaatgaa gaacaaacag aagatcatga agaaacgaac acttcattgg aagaacaaac
    12601 aagtaatcct ctggatgaca cagaagaaat ccctatgcta gaggaaacaa aaatacacga
    12661 aaaagaaaaa gtaactccga cgaatacgaa tactgcagaa aacacccatg cttacgaaat
    12721 aactgaaaat cccgggtatt tagaaggaaa agagcaagat catcaagata tcgtcagttt
    12781 gattgaaaca gcggaagcag aattagcgga tttacgtatg agaaaagatt tgatcgaatc
    12841 agattttcca caattattag aatcatatga tcgttttata ttgaatgaag aaccaatctc
    12901 cacgatcgga aagacaagcc tgatcgaata cttcacgtat gaattactga aaccgttgaa
    12961 tgatattggt ctggaacggt caaattcagc ttatgacaca tggaaaacaa gacatttttc
    13021 gatcaattat acgttgaatg gacaaaacga attagtcttt tcctttgtat taccgaccat
    13081 cgatcaacga taccaagtgg aatcgatgag tctcctaaac gtatcaccag agacaatgga
    13141 aatcaatgtc caagatgacc gggtgctttc tttgatccga cactggtcag tggatcgagt
    13201 attctctgca gggcagatca cgatattcaa tcacaaattg aatcaattat tagcccatgc
    13261 aagaacactt ggttttaccg ttaatcagac attactagac aatacgaagc cacttcgttt
    13321 gaatcttcag agcgaatttg aattgacgaa tgaagtattg gatgatattt ttatcgtggc
    13381 aatgaaaaat ccatcctacg atatggaaaa gatcaacgaa actacttatc aagtacgatt
    13441 agataaagga cagtctttaa cgataacaac aaacgaaaaa gatcaaacag tcttgtcgat
    13501 ctcatctgga gactacccac gatctgtcat tgatttcttt atcaattacg aattcttggt
    13561 cccattaatg gtgagaaagt cctgattgga taagttggat taccagatgt cattcagata
    13621 attctgttcc aaaggacttg cggcagttat ccagaataat tgtcacaagt cttttctgta
    13681 tgtactaaat ggacgtgaat aacttgctga tgaaggaggg atttcattag gaatgtccac
    13741 aaataaaata gcacagctta gcttattgtc tgctgcttgt gtagcaggta ggatcgcttt
    13801 tcaatttatt ccgaatttcc agccaatgac tgctattttt ttatttatag tactttactt
    13861 aagcttaaaa gatgcgttaa ttgtcatgag tctttctatt gcgatcagca gtttttattt
    13921 tggtgttgga ccatgggtca tcggccaatg gatcagctat actgttgttc tgagtttgtt
    13981 ttcaatcgtc tgcttgagaa aaacagtgca aaggaatcta tggttaaagg gagtctgttt
    14041 ttttctggcg ggcatggttt acggaatagg tatgaccgtt tttgatacgc tgttatatcg
    14101 tttgcctcaa ccttggatct attaccttca aggggtgtcg tttgatttga tgcacagtat
    14161 aggcaatgtt gtgttctttc ttgtttttct gccagtcgtc aaacgttttt acaatcattc
    14221 aggaggaaaa aatgaaaaaa ataatttata gtttgcttgc aatgagtgtc agtatactca
    14281 ttttgacaag ttgcagtaca acctatacac aatcggcttc caaccaaaag gaggaagtaa
    14341 aaacatcgca aaaagcaaca atcacgttac aagaaaatgg tcaaaacttt tcggaaaaag
    14401 aagtgttctt caaaaaaggc gatgatttac tgagtatttt gaaacgaaat tttgaagtca
    14461 aagaagataa cggcttcatc acttcgcttg aagggcactc acaggatgag aaaaatcaac
    14521 tctattggat gtttactgtg gacgggaaaa gtgctactac tggtgccaaa gagatcaaat
    14581 tgaatgatgg acaatcggtc attttcaatt tgtctaaact ataagtttca taaaaaactg
    14641 ttaaagggcg aatattgcca taattcagtg agttcagttg atgaaagaag gaaaataaca
    14701 tggaaaattt taaaaaaagc ggaatgtttt ccgtaattgc tgctctaggg gctaatattc
    14761 tagttgctat cagcaaattt gtcggctatg caatcagtgg cagtgccgcc atgctaaacg
    14821 aaagcatcca cagtatcgtt gattgcagca atcagatttt gctgttattc ggtgataaac
    14881 aagccaataa aggacagagc gagttgcatc aatttggtga aggacgagca aaatactttt
    14941 tcagtacaat cgtcgcaatg atgcttttct tcggcggtgg ggcacttggg gtgatggaag
    15001 cttttgaaaa gttgacgcat ccatcccatg aagtgggtaa tccgatcatt gttatagcaa
    15061 tactgttatt tggtttggta atcgaaggaa gttcgttacg cgtggcaatg aaagaaatca
    15121 aagaattgaa tactgaaaaa ctttccacga tgcgcttttt gcgcgaaagt cgacacagtg
    15181 aaatactgat tatttttacg gaagacttgt gtgctgtaat cggtttggtc ttggctttag
    15241 caggaacaat attgacttat gcaaccggga ttgctgcatt tgatgcgatc agcggattgc
    15301 tgatcggttt cttgctgatg ggagccgcca ttttcctagc aaaagaattt tatagtctga
    15361 tcatcggtga aagcgtgaca gcaagcgatt tatcaaaaat caagttagct tttgaacgtc
    15421 ctgagatcag tcggctgatc gatataaaaa cagttcattt aagtccaacg gagattttag
    15481 ttgcagcaaa agcagatatc gttggtaaca aagagaatga agcttactcg gtcatcaatg
    15541 atattgaaaa aaatatgcgt cagtctcttc ctgacaagaa gatgtatata tacattgaaa
    15601 cagataaata tgacccaaat tattctcgta aataaaacgt ttattcatga attgaagcaa
    15661 aaatgagaaa aatataatct tgtttttaaa taaaacggct acaatttagc gaatttatgt
    15721 tacaatgagt ccgctgttta tttgttgtaa ttaaaggaga tattttaatg aacaaaaaga
    15781 aaagtgcgcc atggcttcaa gctttgcatg cagtgatgcc actttgtata agctatatac
    15841 cagtaggatt agcttgcgga gtattgttgc aaaaagttgg atttgatcct ctcttatcag
    15901 gactgttatc gattctggtc ttttccggtg gcgcgcagtt tttagttgca tctatgctta
    15961 cgacgcaagc atcatttgca acgacattat tgatggtttt ctttttagaa ttacgctata
    16021 cattattagg agcaagtctt gccggtttta tgaaaaaaga aaagcggacg tttttggctg
    16081 tcttttctca atcactgaat gatgaaaact atgcggtgaa ctacttaaag ttttcaactg
    16141 acccttcctg gaataaaaga aaggctttat atgtcaattg gttctcaatg actgcatggg
    16201 ccggtagcaa tatgatcggt aattttttcg gctcggtgat tcgagtagat gctgaccttg
    16261 tccattttgc tttgacggcc atgttcattt tcatgtttat catgcagatg aaaagcgcac
    16321 tactgatctt tacaggttta ttctcaggcg tattaggggt cgtattcatg gtattattcc
    16381 aaaatacttt cggattgatt gcagcaacag tcattgcttc atttgccgga tttatgctgg
    16441 agaaggcatt caaaaaagaa aaagctaaga aactaagaga ccgcggtaaa gatgtcaatg
    16501 agccgctctt caacttcccg gaacaggagg ccaatcacca tgactaaact atatttgcta
    16561 cttttagttg tttgtctgtt catcgtggca tatatcccgc gcttgttccc gatgctttat
    16621 tttactcatc gaaaagtgcc atcctggttc agtgactgga tgaaatatgt accggtggca
    16681 ttatttgcgg cgttagcttt taaagatgtt ttcattactc atgaacatct ggatattgct
    16741 tggaatatca aaatagctgc aatgattcta gtagcaggcg tggcttacaa aacacgttcg
    16801 atggcgttgt cagttttgac aggacttgcg tctgtctttt tgctgtctat gctttaaact
    16861 gttttatttt attaaaaaca gagattgcga cataagttgt tcaaactgat ctatccgaac
    16921 tgcatttgca acagtcaatt ctggatgcaa gtttattcgt agggataaaa aagattagtg
    16981 ttggcttatg atgcaagctc ttttttattt taggaattag agagggattt gtccttctat
    17041 gattttttgc tataataggg aagatgttta ttttatgaaa gaatagttga gggaatttaa
    17101 atgaataaaa aattgatgca aggaacattt tggctaacct ttgctaatct tctatgtaaa
    17161 gttttagggg tagtctattt gattccctgg ctaagtatga tggggaacaa tcaagatggt
    17221 atgcttgcta cgacattgta taatgttggc tatcttcctt atggattgtt cctgatgctt
    17281 ggtacagtcg gatttccaaa tgcgattgca aaaaaagtag ctgtagccac aaaagaagga
    17341 gataacgctg cttgtcggct gatttttaga agtacgatca atatcatgtt tgtcatcggt
    17401 atcgcctctg ctgcactgat gtatttattt gctcctttac tagccggaat cagtccgatt
    17461 gctaacgtta ataatgggat actagctatc agaagtttat gcccatcttt gattgctatc
    17521 ccaattctta gtgcaatgag aggatatttc caaggaaaaa atgatctgcg gccttatgga
    17581 acttctttga ttatcgaaca ggctgtgcga gtgatcgtta tcttggctgg tacttattac
    17641 ttgcgcgtat tgactgacgg aaccatatta gaagctgtat tgatcagtac agtcgcttct
    17701 ttcttcggtg ggttagctgc gattatccat atgtatatcg tcggacgcag aaaagacttc
    17761 ttcgaactta aagatttttt gatttccagc cgttatttcg aaagagaaaa ccgatctgcc
    17821 tctgtctcta tcattcggga aacactaccg tttatttttg tcggctcagt cattactatc
    17881 gttcaaatga tcgaccaagt aacgatgaaa ccactgcttc actttttccg tccagagatc
    17941 gcagatcagc aactggaatt cttattcagc cgtgcttctg tcaatccaaa taaattgaca
    18001 ttgatcctga tctccatggt aggaacagta gctataagca gcttgccaat attaagcacg
    18061 atgaagaaaa aagatcggat acaaatcgaa aaaacagtag gagatagttt ttcgattgcg
    18121 ttattgattc ttcttccttc attgactgga atgtctttat tagctggacc actatacaca
    18181 ttgttttttg gctatgatcc tgaaagtgtc ggatatttcc aaatggcttt gctagcttct
    18241 ttgtttttct ctttattcac gatcctatct acgatgcttc aatctttgaa tcaccatcgt
    18301 tttgcgatcc gattaactgt agaagcaatt atcctgaaag tcatcttcca agtaatcgga
    18361 ttaggattag ttggcggata cgggatgagc ttatcaaatg gcttagcatt cggtattgtc
    18421 tttgttcgcg gctatcactt tatgtgcaaa gaataccgaa tagcaccttt agcaaagatc
    18481 agcaattttt tcttaaaaac tttccgctcc accctgatta tgcttgcagt atgttttgcc
    18541 gttttctttt tgctgaatca gcgattgtca atggaatcaa aaagctatgc aatgatttat
    18601 tgtgtggctg taggaagtat tggcggctta gtatttttat tttctcaatt cggaaaaaat
    18661 gggtttcgaa tgttgaaaaa tgttaaacat catagcagaa gcaaagaata ggttaactaa
    18721 tcgttttttg ctgtcacttg aaaaacggca actcgtatga ttacgcttgt cgtttttcta
    18781 ttttccaatt ttagtttcat atctaatctt acttatgata tagttataag gtctggaaaa
    18841 attctttgaa acgaggaaat taaacacatg aaacttgcag tagttacaga tagttcggca
    18901 tatctgccgg aacgtatcaa gaaccatccc gacttattcg ttattccaat ccctttgatt
    18961 atggatggga aaatttataa cgaaggaatc gatatcgaag cggatgaata ttatggactt
    19021 ttaaaaaaca gtaaagattt tcctactact tcacaacctg tcgtagggga agttttgggt
    19081 ttatatgagg aattgaaaga gaaagggtat gacacgattt taagtatcca tctttcttca
    19141 gggatttctg gctttgtcaa cacattattt gcgatgaaag atgacatcag cggagtaacg
    19201 gtcattcctt atgactctaa gatcactagt atgccgatgg gacacatggt agaagctgcc
    19261 ttagacttaa atgatgaagg tcagtccctt gatgaaatac ttgcacatat cgatcgaatc
    19321 cgagataata cctacgctta tctgattgta gatgatttga acaatttagt acgaggagga
    19381 cgtttgacaa atggtgcagc gctgattggc agcttattaa aaatcaaacc gatcctgaca
    19441 ttttctgaag ggaaaattgt tttattcgaa aaaatccgtt caagtaaaaa agcatttgct
    19501 cgagctgaag aaattattgg tagaagaaat aacgaaatac aaccgccagt caaactttac
    19561 gtgatacatg caaataattt agaagtagcg attgcggaga aagagaaatt gcagaaaaaa
    19621 tatccaaatg cagaaatcga aattggtcat ttcggaccag tcattggtac acatttaggt
    19681 gaaaaagcca tcggcattgc catttcagcg caataattcc ttttattcaa aaaacatacc
    19741 aaaaatattc caacatcatc ttggactttc tacatgttac taatgagcgt gtaaaagaac
    19801 gagatggtgt ttttatttct atcaatgaag ctctttttct ttgcaatcct cacttcaatc
    19861 ctctataatg tcgcatatag tttagtaaat gagtaaacta ctaatttact tatttactaa
    19921 aaataaaagg atgaggagtt aaaataatgg aaataccaac aaatttaaaa cataaaccag
    19981 taatcgttgt agaagactat gataaagttg atggaagaaa tgcattaaat acggatgcaa
    20041 aagggctttc actgggcctt gctcagtgga atgatcgtgg aaaagtcgat atctcaggca
    20101 aggtatggcg acatactgga gaaaaatggt cacgacagtc ggaagaatta ccaatcacac
    20161 gtattttaga tttagcgatc ttagctgcac aaggaagttt atacttccaa gatgcttatc
    20221 gttatgaaaa attttatgat ccagaaaatc cagtcgtaga catcattgga ttacaaggga
    20281 accgaatgac ggtagaagta gataccaaaa atccaaagat cgatgaagac atcattttgt
    20341 attacgatac actacaaaaa gacggagaac tgattgggga acgattccgt attttaaaac
    20401 gtcttttaga tgagctagga tattaataga cagagatgat caaaagggga agagaagcat
    20461 ggagaatttc tcactaacag aaaaccgaac cttttcacgg ctagaaaagc aaatgatctg
    20521 gaagaaaccg aaaagccatc ggacaagtgc agaagaatgg cggatcgcct ccgaaatcaa
    20581 agggaattgg caagatcctg aaatgaaaat cagtaacgta cttttggaag gagatgccgg
    20641 gtcggggaag acacaattag ccaaagcact atctgctgat ctgcaacttc cctatacaaa
    20701 agtgacctgt tttgcagata tggacaaatc agatgttttc ggagccttat tacctgtagt
    20761 agattctaat aaggaacaag accaagaatt actagaagct atttaccaaa cagatacact
    20821 tgaagctgta ctgacactga tccagaacca ttacggcatt gatccttttt ctgctaaaga
    20881 aaaattagca gagctagttc aaaggatcga agctgattat ccagatgcaa tccattacag
    20941 ctattaccct tctgaaatcg ttcgagcgat tgaaaaagga tatttattag agattcaaga
    21001 gccgactgtc atccgagatg cctctgttct tgtggcactt aactcagcgc tcgaaccaaa
    21061 tgggatgttg aatttaccga caggaatcat tcgtcgccat ccagattgcg tcattgtgat
    21121 cactacaaat cgaaattacc aaggaaatcg cccattaaat gaatctttaa gagatcggat
    21181 gcaacatgcg gaaaaaatgg atcttcctgc cttagaagtc atggcagaac gtgcgatggc
    21241 gaaaactatg atccaaaaac aagaacttct cttaaagatg gcagagatta tccgtttgtt
    21301 ggatgaaact gcaaaagcta acgccatcaa aggtgtagca ggaatgcgtt cttattttta
    21361 ttgggcaaat acctataagc aaggacaaga tttactccag tcgatttatc caaaagtttt
    21421 gtataaatta tccactgatt cagatgaatt ggcaattctt gaacaagctt tgtctgacag
    21481 tggattgcta ctggaacttc aggacatatt gagaaaagaa aaatggggtc atcctcaatc
    21541 tgagcataca aaaggaagaa ccattagcgc cgaagaagca aatgaacgaa acatcactga
    21601 aaatgctgaa gaaattctgc gcttagatga aaagaaatcg ttgtctgctg aagaaccaaa
    21661 tgagggagaa gagaaacaag aagaaacaat agaaaaaaac gagattcctc ctcaaatgca
    21721 aaaagaacgc agtagcgata tcgaaggaaa aaatcaaaaa gaacaacaaa caggagatga
    21781 ttctcaagaa atgtctgctt ctgacatgga agcacatgat aaggaaatca agaagcaact
    21841 gaataaagaa gcgcgacaaa tcatgaagga aacgattcat gaaaaagaag gtctcatcgt
    21901 tcaccgacca gctttccaag gaaaaacgcc ggaagcacgt gagctacaca tgcaagtaat
    21961 gccaatagta gaatcactta gccggcaaat tttagagtta ctggataatg aacaaacaga
    22021 gacgtaccaa aaaggaaaat acgaaggtca gcggttcaat gcaagcaaag tagcatatgg
    22081 tgatttgaga aattttgaca aaaagaaccc gccacatgag caaccttctt tagcggtagc
    22141 tgtacggatc gatgaatctg ggtcaatgat acgggatgat cggatcgaag cggcaaaaaa
    22201 agcagcgatt gccattgccg aattttctaa gaaagtcgat atcccattgt tgatttacgg
    22261 agatacagca gaccgttcgt caagagaaaa gacttctttg ttttcttata aagaatttga
    22321 agacggattt caatggttaa atgaaaaatt agtcactatg aaaccaaggc aaaacaatcg
    22381 tgatggtgct gcacttcgtt tagcagcaga aaaattaaac agacaatccg caacaaccaa
    22441 actgttgctt aatattagtg acggtcagcc aaaagcgttg ccggattata caggcaaaaa
    22501 agcaaaagaa gatatccagt ctgttttgaa agaatatgaa cgtcaaggaa tcctatttgt
    22561 ctccgcagct attggccaag acaaagaaga aatcaagtcg atctacggtg aaagtcgttt
    22621 tgtagatatt actgacttga atgaatttcc caagcaaatg attcaactga ttgcccgcta
    22681 tctatgataa aataaagctc aacgaacgca cttagcagat tcgttgagct tttcgtttct
    22741 agttaccggt aacaaggata cttctaaaat agaatcggtt ataatcaaga gggaccgtta
    22801 aaggagtgaa acgatatgat acaagaacaa aaatggtgga aagaagcagt aggctatcaa
    22861 atctatcctg ctagtttcaa agatagcaat ggcgatggtc aaggagacat caatgggatc
    22921 cgtgaaaaac ttaattattt gaaagatctt ggtatcggct ttatctggat caatccgatc
    22981 tatcaatctc catttgtcga taatggttat gacgtaagtg actatcaaga tatagaagag
    23041 agattcggaa cgatggaaga ttttgattta ttgctaaaag aagcacatga attagggatc
    23101 aaagtgatta tggatcttgt catcaaccat agttcggatc agcatcaatg gtttgaagaa
    23161 tcgaaaaaat ctaaagaaag cccgtatcgc gattattaca tttgggtcga cggggtagat
    23221 ggcaaagaac cgaataattg gacatcgatt ttcggcggtt ctgcttggga gtattctcat
    23281 gaaactggac agtattatct gcatgttttt gcaaaagaac aaccagactt aaattgggaa
    23341 agcgagaaat tgaaagaaga actattcaat atgatccgat ggtggttgga taaagggata
    23401 gatggatttc gtttagatgc gatttctcat gtaaaaaaag atgaatattc agtaaaagcc
    23461 acagagaacc ctttctcacc ctttcaaaat gtctcaggaa tcgaagaaca tttgaccgat
    23521 ttgaaacatg tttttgaaga gtacgatatc atgactgtcg gagaagcaag tggtgtcact
    23581 gcagaagaag gaccacaatg ggtagggaaa gacggttatt tcgatatgat attcgaattt
    23641 gatcatatcc atatctggca gcaagaaaaa gaagggcaat tagatgtcct taaattgaaa
    23701 cttgcattaa gcgcttggca aacttcattg gatggtatcg gatggaacgc tttatatatg
    23761 gaaaaccatg atgttcctcg tgccgtttca gtgtttggag atactcgtcc cgatttttgg
    23821 gctatgtctg caaaagcaat cgctatgatg tatttctttt tgcaaggtac gccatttatt
    23881 tatcaaggac aggaaatcgg aatgacgaat atgccctttg aatcgatcga tcaagttgat
    23941 gcagtagatt cgaaaagact ttataaaagg ctgcttgcgg aaggtaagac aagagaagaa
    24001 gcattggata tcattcgtga aacaacgaga gacaacagca ggacacccat gcaatggact
    24061 tcggaacaat atgctggttt ttctacacat gaaccttggc tgatcactaa tccaaatacc
    24121 aaaacgatca atgtagaaca acaagaatat gaaccagagt cggtcctgca attctataag
    24181 aacatgatcc gcattagaca aaccaataaa ggtctgatat acggttctta taaagaatat
    24241 cttcatgaac atccacaact ttatgtctat gaaagatatt tagaagatga acaatatctt
    24301 attatggtaa acttaacaga atcacttgct gactatgaac ttccaaaaga agcagatcag
    24361 tcctggacat tactcttgtc aaattcctct agcggagaat ttgaagctaa aggcatacta
    24421 gcaccttatg aagctcggtt atataaaata aacaagtaaa acttcctcgt taaagttcat
    24481 tagttggact ttgcgaggaa gtttttcaga ttgctctgtc aattactcat ttcaataatt
    24541 cgctctagga ccaccgatat atttaggacg agagcgaagg gctgtcacgt gagcttgtcc
    24601 aagggttttc aaacgaggtc tgacaggtac ttggacatgt ttgatatgca taccgattga
    24661 tgtgtcaccg atatcgatac cggcttgtcc aactacgtgt tccacttcga caggatcatt
    24721 gaactggtca aaagcagcaa cagaacaagc acctccagca tgtagtgcag gaacaacaga
    24781 gacaatttcg aaattttttg cttctgccac tgttcgttct actactaatg ctcggttcaa
    24841 atgttcacaa ccttggacag ctagcgcaat ttctttagga tccaacaact cttttaacgt
    24901 acggatgatc cattgaccaa cttccgcact ggaatttttt ccaatatgtc ctccaacgac
    24961 ttcgcttgtg ctgcatccta aaacaaaaag atcacctttt ttcaagtgtg cctcagccaa
    25021 tatgtcatta actatttcag tcaattggtc ttttaattct ttttctgaca acttcatttt
    25081 ctaaaacctt ctttttcaat taatattgct tccgtgcttg aatacgttga agacttgcag
    25141 ttataggaaa ggcaagtccc attccaatca gattttggaa gatgtttcct ggtatagaag
    25201 ccactccagc cggccaatca tataaaatcc aaccggcgat accatagccg atgatcataa
    25261 ctaagcttcc taataaaagc cctaatcccc acatacgagt agaagatttg ctgaaagaac
    25321 cagcaacata tccttgtaac ccgtggatca ctaatgaaaa aactgcccac tgcggatatc
    25381 ctgaaatcaa atcgatcaat agaccactgg aagcaccaac aactaatcca cccgttggac
    25441 cataaagaaa agcagcggta tagatcccgg cctcgcataa tgtcacaaat ccattcgtag
    25501 ccggtacagg gatcaaaatt gttaatgaaa gggcaactgt caacgcaatc agcatagcat
    25561 agatcgttaa ttgcttagtt ttcatttctc attcctcctt tttgaatacc gccagaccag
    25621 acacttccgg tatgatcgtt catcagcacg ccattagaaa tacaatgggc aacaaatttt
    25681 ttactttctg ctactgcttt ggtaaaatct gcccctaaca caagattcgc tgttattgca
    25741 gaagaaaagg cacaaccggc cccgtttact gttgtagtgt cgattttttt atgagaaaat
    25801 acctcataat gatcaattga atagagaaga tccacagctt catctccagc catccttgtg
    25861 ccgcctttga tcacaatgtt ttttgttcct gaagcagtga gttctttagc gagatggatc
    25921 atttctgtta acgaagaggg aagagcttga ccagaaagta aagcagcttc tgccaaatta
    25981 ggcgtaatca tcgtaacaag tggaaaaagt tcttcgatga gctgcgaaat atacaattga
    26041 ttgatcacag cttcagtttc tttgaatgcc aaaacagggt ctaaaatgat tgggatattt
    26101 tgttttgttt ttatgaagtc tcgaacaacc atgattgctt cacttgaatt caataaccca
    26161 attttgatac catctaatga agtcatttta tcaatcgaaa ctaactgtcg tttaagcaat
    26221 tccaaagata tagattccag cataaatcgc tcattaatat ctagtgcccc tatagaagtc
    26281 aaggcgctta gtccgaatag accaaaattc tcaaaagttt ttaaatctgt ttggattcct
    26341 ccaccagcaa atggatcaga accgccaatt gtcaagattc ttttcataac attttcctcc
    26401 atgaataaga gtataacgaa attttcaaaa aagaaaaaca gccaattggc atatttttat
    26461 ctcatccaat ttaaaaaaac aaaaagaaaa gaaagaccaa aatggatctt tctttcctta
    26521 aatagttagg acttttgtga ttttaattct ttctcgattt gaagccgttg cactttcatt
    26581 gtagctgttc gcgggattgc atcaaaatca cggatgatag ggacgttcaa gcgaggaagt
    26641 tcatggactt gctcccacca tcgattccaa tccatttctt tatcaggagc taaagcaata
    26701 atcggttgtg gagaatgatt tttatccctt acaatcacta cttctgccaa aaaatctaac
    26761 gaatctaata aaaagtcttc aatagctaat gtactattga tcgtttcgat caaatccact
    26821 tgccgatctt tcaaaaatag gtggccatgc ttatccataa aaccgtaatc tccgctatcc
    26881 caccaatcgc cataaacatt ttcctggaac cgtgcatctt ccttgtaata agtcaaagcc
    26941 cgtcctttag acagtaattg tatatgacca tctgtgtttt caggtaggac attcccaact
    27001 gaatctgtaa tccgagcgct tgtcatgtct tccagtccaa cgcccatatc tcttgcatca
    27061 cttgttttca aactctctag tgtatgagcc ttaagaatca ttggtccgca ttcactttgg
    27121 ccatatactt gaagaaatac cgcatcctgt gccatcgacg ttcgcaaaaa tgtcttcatt
    27181 gtctggttgt ttatagcatc aaaagtggag tgatagtatc ggatacccga aaaagcttct
    27241 ggatgctcct tagcagtaaa acgccactga acaaagttat tcggatgggt ctctagtgca
    27301 attggccggt gagcttccaa catatgaaca acttttgaac tttgtgcgtt tgctaaaggc
    27361 atcataggaa atcccatgga catcaaagaa gagataccaa tattgaatct ggaatgcact
    27421 ggagagatgt gaaaagcgat taatttcttt tccgaaattt ttgtgaaaac tgttttttgc
    27481 catttcgtcc gccatcccat agaatgagca gaatgacaaa taagtttagg gataccagtt
    27541 gtaccagaag tatgggtcat ataagaaatt tcatttttgt ctaaaaatga ttgagaaaca
    27601 gacaaagcag gttgttccat taaataaaga atagg
//
LOCUS       DAFBSV010000031        27026 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.032, whole genome shotgun sequence.
ACCESSION   DAFBSV010000031 DAFBSV010000000
VERSION     DAFBSV010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27026
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.032"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..943
                     /locus_tag="LLB18_001252"
     CDS             <1..943
                     /locus_tag="LLB18_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5244264.1"
                     /translation="SQSYSIVLASRAGLGIGFGLINSLAVSMIAAFYHGDERASMIGF
                     QSAFQGFGAALMTFVAGQLVQFGWQYTFLVYAISLPILVLFVLFVPTPETTELQSHGT
                     APTRQVIKTNPKMISYGIFLLLVIVVYNAVSIKLATVLTTYSLGNETNAANILTIMQL
                     ASMAAGVCFGWLQTKAHRYMLTLSLLLMGIGFVLIATVINLYVIGFGAILTGISFSLF
                     IPYLFNQVSIQAPKYAESFNTSILLVGANLGTFIAPYGLLFLSFASLGSKTLAVFVNG
                     SILLLISALISLLVVHRTNRKTVIRVDEEIKEQLTTK"
     gene            965..2980
                     /locus_tag="LLB18_001253"
     CDS             965..2980
                     /locus_tag="LLB18_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HBK5244265.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(3063..4436)
                     /locus_tag="LLB18_001254"
     CDS             complement(3063..4436)
                     /locus_tag="LLB18_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBK5244266.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(4462..4746)
                     /locus_tag="LLB18_001255"
     CDS             complement(4462..4746)
                     /locus_tag="LLB18_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5244267.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(4748..6763)
                     /locus_tag="LLB18_001256"
     CDS             complement(4748..6763)
                     /locus_tag="LLB18_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBK5244268.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(6942..7247)
                     /locus_tag="LLB18_001257"
     CDS             complement(6942..7247)
                     /locus_tag="LLB18_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HBK5244269.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(7336..8367)
                     /locus_tag="LLB18_001258"
     CDS             complement(7336..8367)
                     /locus_tag="LLB18_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBK5244270.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            8574..9449
                     /locus_tag="LLB18_001259"
     CDS             8574..9449
                     /locus_tag="LLB18_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBK5244271.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(9601..10443)
                     /locus_tag="LLB18_001260"
     CDS             complement(9601..10443)
                     /locus_tag="LLB18_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBK5244272.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(10535..12412)
                     /locus_tag="LLB18_001261"
     CDS             complement(10535..12412)
                     /locus_tag="LLB18_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBK5244273.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(12409..13830)
                     /locus_tag="LLB18_001262"
     CDS             complement(12409..13830)
                     /locus_tag="LLB18_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBK5244274.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(13833..17222)
                     /locus_tag="LLB18_001263"
     CDS             complement(13833..17222)
                     /locus_tag="LLB18_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBK5244275.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            17479..18871
                     /locus_tag="LLB18_001264"
                     /pseudo
     CDS             17479..18871
                     /locus_tag="LLB18_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(18944..19591)
                     /locus_tag="LLB18_001265"
     CDS             complement(18944..19591)
                     /locus_tag="LLB18_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBK5244276.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(19599..20285)
                     /locus_tag="LLB18_001266"
     CDS             complement(19599..20285)
                     /locus_tag="LLB18_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5244277.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(20291..21364)
                     /locus_tag="LLB18_001267"
     CDS             complement(20291..21364)
                     /locus_tag="LLB18_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5244278.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            21586..22260
                     /locus_tag="LLB18_001268"
     CDS             21586..22260
                     /locus_tag="LLB18_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5244279.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            22265..23605
                     /locus_tag="LLB18_001269"
     CDS             22265..23605
                     /locus_tag="LLB18_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK5244280.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(23754..24740)
                     /locus_tag="LLB18_001270"
     CDS             complement(23754..24740)
                     /locus_tag="LLB18_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HBK5244281.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            25464..26495
                     /locus_tag="LLB18_001271"
     CDS             25464..26495
                     /locus_tag="LLB18_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBK5244282.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            26604..>27026
                     /locus_tag="LLB18_001272"
     CDS             26604..>27026
                     /locus_tag="LLB18_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBK5244283.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQI"
BASE COUNT         8012 a         5055 c         4931 g         9028 t
ORIGIN      
        1 ctcacaaagt tacagtattg tcttagcttc aagagctgga ctaggtattg gctttggatt
       61 gatcaattct ttggcagtca gcatgattgc tgccttttat cacggagatg aacgagcctc
      121 tatgattggt tttcaaagtg catttcaagg atttggtgca gctttaatga catttgttgc
      181 aggacagcta gtacagttcg gttggcaata taccttttta gtctacgcca tcagcttacc
      241 tattcttgtc ttgtttgttt tgtttgttcc tacacctgaa acaactgaac ttcaatcgca
      301 tggcacagcc ccaacaagac aagtaatcaa aacgaatcct aaaatgatta gttatggtat
      361 ttttctcttg ctggtcatcg tggtatataa tgctgtatcg attaaattag ccacagtcct
      421 gacgacttat tctctaggaa acgaaactaa tgcagcgaat atcttaacaa tcatgcaatt
      481 ggcaagtatg gctgccggag tttgttttgg ctggcttcag acaaaagcac atcgctatat
      541 gcttacactt tctttactac tgatgggaat cggctttgta ttgattgcca ctgtgataaa
      601 cctgtatgtg attgggtttg gtgcgatcct aacaggaatt tctttttcgt tattcattcc
      661 ttacttattc aaccaagtaa gtatccaagc gcccaagtac gcggagagtt tcaatacttc
      721 aatcttattg gttggcgcta atttaggtac tttcattgca ccatatggtt tgctctttct
      781 ctcttttgct tctcttggga gtaaaacact tgctgttttc gtcaatggca gtatcttgct
      841 gttgattagc gcgcttatta gccttctagt agtacacagg acgaatagaa agacagtgat
      901 aagagtagat gaagaaataa aagaacaatt gacaacaaaa taaatttgat ggaggtcgtg
      961 taaaatgaca aatgaaaaac ataaagatag atggctttgg tatcctggag actttgagat
     1021 ccgccatgga ctgctacaaa atttccaacg ggaagaacga ggttttgact ggccagcgta
     1081 ctggtacatg gatgattgcc atcggaacgt caagtttaag agatattact ttcttgatca
     1141 accttccatg tttaaagtga cgatccaagg agttgggtat gtagaaatta atggacaaaa
     1201 acatccatgt ggaaaatggc tgacttgtcc agctggtaaa gcaaaaattc gtatctttgt
     1261 aggacataca tcagggctac cagcgatgtt tatcgaggga gacgaagtaa aatcagatat
     1321 tggctggaca gcaagtaatt ttattgaaga atatccagct ggctggagtc cgctttatgt
     1381 cgatatcgca aaagatccaa atcaaatcta ttatcaaaaa gaatgcgtcc atccagtcac
     1441 tgaaacggag attggcggag gaatcttatt cgattttggg cgagcagtga atggctgtgt
     1501 agaactaata tctctggatg accatatcga atctatcact ctatgttatg gagagtccga
     1561 tgtagaagct atggatatcg attattgcta ctataagcaa ataggaatga caagaaaaat
     1621 gaaagctcgt aaacgcgctt ttcgctattt gtttatacca gaggtttcta ctggaatggt
     1681 tcaacttcaa gtttttcatg aatttttatc tctttcgaaa caagctgctt tttcaagcga
     1741 ttcttcttta ctgaatcaga tctggtcagt atcagaagaa gccttcaagt tatgtagtga
     1801 tttgtttttt atcgacggta tcaaacgaga tcgctggatt tggtctggag atgcgtatca
     1861 atcattcatg atcaatcaat atcttttttt tgacgaggaa atcaataaac gaacgatatt
     1921 agcattaaga ggacaaaatg aaatcaagca gcatatgaat actatcgttg actattcgat
     1981 cttgtggttg attggtatcg aaaaccacta tatgatgacg aaagactatg aatttttacg
     2041 catcgtctac cctaagatgc aatcattaat gagatacttg atggagcaaa cgaatgaatt
     2101 agggtttatt tatgggagag caaaagattg gatatttatt gattggtctg aaatggataa
     2161 agaaggaacg cttgctgcag aacaagtctt attactgaaa gcctatcatt ccatgatcac
     2221 ttgcggagat atcttagctg aaacatatgg agagaacgaa aattatcata ctcatctcta
     2281 tcaagaaaaa tatcaactat tgaaacaaaa cctatttgac tacttttggg atgaagaact
     2341 tggcgctttt atcgattgct atgaatctgg gagaagaaat gtgacgcgtc atgcgaatat
     2401 tttcgctgtt ttattcgatt ttgctaacaa agaccaacag caatcgatct taaagaatgt
     2461 cttattgaat gacactatca cacagattac tactccatat ttcaaattct atgaacaaga
     2521 tgctttatgc aaactcggac agacgaatat cgtctaccaa acgattcttg attattgggg
     2581 agggatgtta tctcatgatg cggtaacttt ctgggaagaa tacgacccta ctcaaacagg
     2641 aaatgaaaag tacagtatgt atggagatcc ttatggaaaa agcttatgcc atgcatgggg
     2701 agcaagccca atctatcttt taggacgcta ttttatcggt ttgtatccaa caaagccagg
     2761 ttatgaagaa tttatgatac aacctaatct agattcattt gaaacactga attgtacgct
     2821 acctatcaaa gatggaaaga tttcgcttga aaaaacaaaa gataagatcg tgattacttc
     2881 tgatagaaca ggcggaacag tgaaaatgaa tggtaaaagt tatcctcttc tagcaaaaca
     2941 gccacttgtc ttaacaagct attcaaaaat aaatgcataa aacaaaaaac tgcttgcgac
     3001 atatcagaag actttaaatc ttcttctgat attgtccaag caatttttat tttgaagttt
     3061 gcttaattct gttctttaga aacaatgttt gttctttttc cggcaaaaag aaagctagat
     3121 aatacgacaa gtaaaaagaa agcgatgatt ccaactgtca aggctatttg accgtattct
     3181 cctagtttcc caagtacaag tcctggtact agataatcag tatcggcaaa tgtagaagaa
     3241 gcgattttaa gatctcctaa tactggaagg ataaataatg gcagccaact aatcaataag
     3301 ctattgaaag cagaacctaa taccgcccct cttctaccgc cagtcgagtt gccgaagaca
     3361 ccagaagcag ctccgcagaa gaaatgtcct actaccccag gaatgataac tgtagtttgc
     3421 aagcctatca tagcaaacat ggatagtgtt cctacaaaga agctaacaaa aaagccaatt
     3481 aatacagcat taggtgcata tggaaaaacg ataggaacat ctaatgctgg tttagaatcg
     3541 ggtacgagtt ttttagcaat cccttggaat gctggaacga tttctgccaa caccattcga
     3601 accccttgaa ggacgataac aaacccagct gtgaatgttc cagcttggat cagtgcaaag
     3661 attacagcgt tgtctccatt gcttagttct ctttcaacaa atccaggacc agctaacaaa
     3721 gcaagtgcga catatacgat cgacatcaag agcatgatcg atacagtaga atctcgcaaa
     3781 aagctgaaac ttttaggaat ctttatgtcc tctgtagaac ggtctttgtt tccaaaaaac
     3841 tttccgatcc atccactaga agcataaccg atatttccgg tatgccctaa cgcaacttga
     3901 ttgtttccag tgatgttctt cataaacggt tgacaaagag caggcgtaat agttaatagt
     3961 gttccttcga agaccccgcc taataagatc atccacaaat ttgcagtaaa ccccgcgctt
     4021 actaaaatga ctgctgttag acaagaaaca taaagcattg cttgacctgt aagaaaaatg
     4081 aatttatatc ttgtgaatct agcaagtaaa atattcacga tcatccctac tagcatgatc
     4141 aaagcagtag gtgtaccgta ttgttgcaaa gcaatcgcca ctactgcttc attgctagga
     4201 actactcctt gagtatgcag agctgtttgg aacatcgaag caaaaggggt tagtgaatta
     4261 ctgattaaac cagcaccgcc gatcagtact aggaatccga caaatgtttt gatagttcct
     4321 tggatcactt ctgaaaattt cttcttctga agaacgagac caagcagtgc aatcaaagaa
     4381 acgaggatgg agggctgact gacgattgac acaaacaaat tcaacaattt atccattgat
     4441 agttcctccc ttgaatcatt tttattcttt tgacaagatc ttcgttactt tttcttttac
     4501 ttcttcgctg tcaatgatcg attgcaaagg tacgagcttt tcatcaggta tagaagttag
     4561 cgtatctttc aaagaatgct caatgaagaa ataatcagcc atatcgctag atacacttcc
     4621 aacatccgta tgacttactt caaactcgtc cacatctgct ccaagatctg caagtgcttg
     4681 tttgatgttc atctctacca taaaacttgt tcctaatcca ctttgacata ctgcaaaaat
     4741 tttcatatca ttcgtctcct tttcttatga tcgctaatat ttcttctttt gttgatgcgt
     4801 gtaataaatc ttgaagattt tgtttattag aaagtagctt tgttaaattt gccaaagccc
     4861 gaagatgtgc ctcattatcg atagcagcta aacagatgaa caaactaatg ggatgggctg
     4921 gattatcaag cagatccaca ggttgttgaa gtttcagcaa agacatccct acttcgttta
     4981 cgccatcttc tggacgagca tgaggtaatg cgatgtgatc gccaatatgg ataaacgcac
     5041 catactgctc cacgcgctcg atcatagctt tgatataact ttcttctatt ttattttctg
     5101 ataatagcgg ctgtgcggca aatgtgattg cttcttgcca gttttttggt tgatccgata
     5161 attggatcat ttcttctgtt aataattcag atagcatagg acgttgatcc tccttctttt
     5221 ctaaaagttt gttcatttta cgatttaata cttgatagag cttttcttcg tctacgcctt
     5281 cttttaattc gatataaggc agtagcgccg acaacaattc ttgggcagaa ggcattgaaa
     5341 atcctggtat cagccaatct ctttgtactt gattgatcag ctgatttttt tccaagtcag
     5401 tcatgattgg atgcagaaca tagagagact ttttcttatc agtaagtgtg agaggtacag
     5461 tagaaaaaat aatatcgtaa gaagtttcgt caacctcgtg taagcggtca gctgaattag
     5521 tctctgtaaa aaagatcatc gggaataatt gctgaagttc actttttaag atcaatgaag
     5581 agctaatgcc acttggacag acgatcacgg ctcttatttt tctatttctt tcttctgcgt
     5641 ccgcttttct gatctctccg ccaaatagta tagtgaaaaa accaatctct tcttcaggga
     5701 tgctcttccc tattcgtctt tctaacggaa gtaatgcttt tcttgtcatt tcgtagatgg
     5761 aagcatattg atgcttaatt tgatcgatca tcacattagg taaataaaaa gaataggaaa
     5821 tacgaaaata ggcagggacc aagtgataaa agacattcat caataattca cgaaacgaag
     5881 caaattctac ggccatcagg aattccatgc gatggatgac ttctgaagaa cattccagca
     5941 aaaaatcaag tgcaggctcc tggacatctc cttcaacgat cgatgctaag caaagagaga
     6001 aaaatataat ctccgaattt tgatgttcgg aatagccaag gccagtcaat acttgtcgac
     6061 taatgtcagt gactgcaaga gaagccaaca gttcagcatc ttttaccagt tccatggatg
     6121 tttttccaat tcgaatggtt gtcaaactca aataataagc taattcatcc attcgatttg
     6181 gtgcgaatcg aagatctgat agtgaaatcg ttttatctag caaatctcta actttggcgt
     6241 aataatcaat ggaaagggtt gcggttaaat acgtgagccc aaatcttcca gcaagtgact
     6301 gcatcaaacg agcagtgcga ttttttgctt ctcttcttaa tattgcttct gaccctagca
     6361 gcctaaaacc agttttccta gtatacgaca gctgacaatc ttccacttct aattcatttc
     6421 ttatcttttt gatatctgac aggactgtcc ctttagaaac ctgaagaaaa tcttgaaaat
     6481 gaaaaacaga aacagacgtt gcagtcgaat aaaccatcaa ataaagaaga tctcttcgct
     6541 cttgttcggt atacacagct tcaaatcgag taatatccaa aaatttttct gcccagtcga
     6601 ttgctcggaa tttctttata cggatacggg tatcatccac atattcggca aaaggagtta
     6661 attgtttgat cgcctcgctt gtatttactt cgatgatctc tgctgctttt tctagactga
     6721 tttctcttgg tgttttcagg agataactaa ttttgtagtt cacagcgctg ttcacctcct
     6781 acttatattc tagtatggta gcgcttttaa atcgaggggt gtttggtaca acttacagtt
     6841 ggattttttt tacgactgta ccgaacgatt tctatcgaat ggatacagaa aaaaagcagg
     6901 tgaccaaatg tctcctgctt ttatgaattg atttcgtccg atcaatgatg atcatgttta
     6961 ttttttgagg tcagttcttc aaatttttct ttgacatctt caaccgcttt ttcgatatct
     7021 ttttcaaagt gattgggctc attaggcttt gtttcctctt ctacagaatt tgaaccagat
     7081 aaagctgttt ctttattttc tgtttcacca gagtttgtgc cagctaatga ttcttctttg
     7141 tcttctgttt caccagaatt agttcctgct aaagccactt cttcttctgt tttaggggcc
     7201 attgaacctc ttaatcgttt gtgtttttca ccgtcataat ttgtcatgtt ggttcctcct
     7261 agtagttcta tactttttca tcgtacaata agacagttta tgcgtcaaaa aacaaacccg
     7321 attcttacaa atatgtcata tttttccttc tgattcttga atgcttttga ttccttcttc
     7381 caaaattttc atttgtaaga ttgtttcttc atctttgatg actttttctg cgccattaac
     7441 taatgtctcg taaatccctt cgtagacacg gctgtaatca ccaacctcgg aaattacttt
     7501 ttcttcatga taactccctt gttcatctat ataggtcaat acaccataat gttcgggcaa
     7561 atcgatacca aagtcttcat gatcaggcat gtaaaacatt ttcagatgtt cttcttgtcg
     7621 atcttttgtt tgtttcacga acatcccttt ttttccgtaa acgacgaaac ttggacgttc
     7681 tttgatgcgg aaataactgg attttatcga aattttcata tttccataga aaaaatccag
     7741 atcgaagtaa tcattcattc gtcctttccc taaaagttga cgtacatcat agctgatatc
     7801 atctggttcg ccgaaataag aaagaacttg atctactgta tgacaagcat gtccatataa
     7861 atagctgttc gcagtagaaa attcatgcgt attttctggt acttccggtc tgaaataatc
     7921 ataatgcatt tctacttcta aaatatcccc taattttccg ctttcgatta ctttttggac
     7981 tgtcaagaag tcagaatcga accgtctgtt ttggtaacat tggataaata gacctttttc
     8041 ttttgctaat gcaaataact cttctgcttc ctttgacgtt tctgcaaaag gtttctctac
     8101 tagtacattc ttaccatgtt cgagtgccat ttttccatat tcataatgaa attgactagg
     8161 tgtagtgatg acaactaatt ggatctcagg atcatcccaa agatcagaca gctgatcagt
     8221 atattcgatg tcttcgaatg ttttccacac tggttcagat ggggaaaaaa tttttttgat
     8281 attgattttg ttcgtaagtt ttcttgaaaa aggcaaatga tagcgatttg tactctttcc
     8341 attgccaaga taagcgattg taagcatgag tggtgcctcc ttttattgat gttttcagta
     8401 tatcctagaa aagcgcagaa agtatttata atagctattc tggtaaaaaa gttcagaaaa
     8461 acacttgtta tcattcggtt tggtgaaatt aatgttcaaa gtaaggataa aaatcaaaaa
     8521 gatagtagcg gaaccaagtg tttatcagta agatagaatt tggaggtcag atcatgctta
     8581 ttgaagaaaa actaacaaaa caagagttgt ttaccacgac agagaaacgg attgtcgatt
     8641 acatccgtag gaatatcgaa gctgcagtct acatgacgat tgaagaatta gcaaaagcta
     8701 cgtatacttc ccattcagct atcattcgtt tatgcaaaaa aatgggattc agcggattta
     8761 aagaattccg tttcgagctg gggcgggaag ttcatcaatt gattgctcag ttcaatcaaa
     8821 cgattgatcc taattttcct ttttcaagtg aagatagcac tcagcaaatt gcaaagaaaa
     8881 tggcggattt atcgatccag tcaataaaaa aagcacaatt gcagattgaa catgaagatt
     8941 tagatcaaat cggtaaagta ttgaacaagg cacagcgaat ctttcttttt gcaaaaggtg
     9001 attctcaaat cacggcaagg aaattccaga ataaaatggt caagttgaat aagtttttga
     9061 tcatggctga agaatacagt gattcttctt ggaatgcagc caatttgact agcgaggatt
     9121 gcgccatttt tattagctac agcggtcgca tccatcatta tgaacgaata atgacctatt
     9181 tgaagcatgt agaggcccct accttgctga ttaccggaaa tcagcattca gaaatggcca
     9241 aacaggctga tatgtgtctt gttatatcgc aggaggaata tgattttgct aaagtagcga
     9301 ctttctcctc tcaaattgcc ttcgattacg tattaaatac gttattctca gtgatatatt
     9361 ctcaaaattt tgaagagaat atccgcaact tgaaaaacaa acaagaattg atgcaaaaag
     9421 gccttcttaa agaatatcgg aaaacttaag aaaagatcct catttagtaa taagaaagat
     9481 agtgtttgat aggctctctt tgatatcatc ataaaaacag gctgaagttt tctttttcaa
     9541 acctcagcct gtttgtttac ggaacgattc gaatagatat attatagaaa tgaggaatag
     9601 ctaacttctg tttcttattt tgaacgattg acgaaaaaga tatataagaa ggaggaaaat
     9661 cagtatacat gcagctaaca atccatacag gaaaaatcgt ttgttctcgg atactttctg
     9721 tacttctttt tgaacttctt ttgcatgata aggaacccgg tgccctctga caagtaagcg
     9781 atgactgttg accatataag gtgtacaagt taggagtgtc acgaaatcct gccctttttc
     9841 gattctcaga tcttttgtat cagtcggttc taccgtcttg atctgatcga cttgataagc
     9901 gagtgtccgt ccattgattt cgatatagaa agaatcacct aaagtcagtt tcggtaagtc
     9961 tgtgaacaac tttgcttgag gcagtcctcg atggctggaa ataacggcat gtgtattttc
    10021 tccccccgta ggataagacg ttccttccaa taatgaggca cctttttcta gcagcacagt
    10081 attcgtttca tcaaaaattg gcaaatggac attgatctca gggatcgtca aaataccgat
    10141 cgtatgtttc tcaaaatagg ttctatcctt tttcgcaggt tcttttttct tagtaaaggg
    10201 atctgcacct ggatttccac cttcttttgc taattgctgg tttttctttg tcatgttttc
    10261 ttggatttta gccatgactt cttcattttc tttgaccgct tgttgctgat aatgagagat
    10321 gatctgctga tccagataat tattcagcgc gtcgctaaca aatggataag ctagtatccc
    10381 tattcctgag agaagcaaga aaagcatcag cagatctaga agtttccttt tctttggttt
    10441 catttgtgtt ctccttgtga tgactgtttg ataataaaag aaaaaggagc atttgcgtaa
    10501 tccgctgctc ctttttccaa ttcttgcaaa aagactaaat ctgactgtgc ttgcgtctag
    10561 caaagtacag tccagcaatc agtagaagga ctactcctgc accgatatac acatagattc
    10621 ccttaccgcc tgttgaagga agtgtacctt tgtgtttatt tggtattttt tcaggagaaa
    10681 tcaactgtcc tgctgttaca taagattgtt catcgatagt aaatgctaca cggtttgtta
    10741 atggaacata tttttctggc gctttcgttt cttccagata gtacgtgcca tattttagac
    10801 ctgtcacatc gattaaaccg ttacttgtgg ttgtaaaaac cgttgctgat tctttcgccg
    10861 atacccagct gacggctttt gtggatgggt cgatcgataa atatttcgct gtgtcactat
    10921 cttgatcacg aacgacgaat tctgctccag caagtgtttg gtctgatgta acgtcaccat
    10981 ctactttaac aaatcgtttg cccccagtaa cgacatcgac tgacggtggt gtttgatcat
    11041 ttgtatgccc gttatcgaca tttgcttggt tagaaaatcc tttggttgga tctgcttttt
    11101 cgttcaaatg catatagtaa acgaatttca atgtaccgcc aggagttaat gaaggaatat
    11161 aattcggatc aactgaaacc gtgaatccgt ctgtttgctc agtgacagaa taatttactg
    11221 ggtcgatttc tttatttcca tcatataagg cataagcata cgttcctgaa gaatcattat
    11281 caaatgttaa agcagcgtca tgagtatcga taagtttgaa tgttgtgtac ttgttttgcg
    11341 ttccttcttt atcagcgata cctaatggga tattgacaga aatctcatat tgaatttttt
    11401 caccgattgc gacatctttt ccattcaatt gaggtgttgt tttatcaact ttagacgtat
    11461 catttttgat ggtcttttct actggtgttt ggctatttgc caggatctca aaaggcgtga
    11521 ttgtttgctt ttcaatcatt tccgcattat caggagcttt tacttcttct aaattatatt
    11581 ttccaacttc taaatgatta acgatcaact ggcctttttc aatagatgcc tcggcaaagt
    11641 cattgttgcc gatgtcataa gaatgaccag taatgaaatg tttggctttg gtttgatcag
    11701 ttgtccaagt gtacaatcca tctgtgacac tttggatgta ttttttgacg cttggtgttc
    11761 cttcttcttt agaaataata aattctgctc catttagtgc ttcgttttcg gcagtaccga
    11821 tttttgtaac tttcaacgtt ccatcattac cgactgtatt tttagggtag agatggatag
    11881 tatctagttc ttctgtcccg tatttataag agccatctgc ttgtttgatc atctcatata
    11941 cagggaaagc taaaaccatg tttgcggcag ctgacactcc gtcttttggt tcttctttga
    12001 tcgtgtagac tgcatctttc ccattttgtt ttttaggtaa agataaagtg acatttccat
    12061 cagcatctgt cgttcctgaa gcaactggtg taccaggagt caaagactgg actgcttgtt
    12121 ttgctgcatc cacggacgct cctttatctc gttgcgcata aaattcttga gtgacgttat
    12181 aaactgaaaa tgaaatatcg gctaatcctt ggtattgatc gaattcgctc atttctttcc
    12241 cgctgttttg gattaaagga tcgggtaaat cagtcatttt ctttttatga aggatgactt
    12301 gagctgctgt ctcctctgca aacacttttt ttgcgccgaa gctgtttgtg agtaatggta
    12361 aaataaggaa aaggactcct aacataacgt ttattttttt atgatttttc attttttcac
    12421 tcctgttctt tttttgataa acaaccagat tgcaaagctt gcgaatacca taccaacaac
    12481 gcctaaaagt gtatttttcg tttcgtttgt ttttggaaga aatggacggc tattttcttt
    12541 tttattgact actttcaata tactgtccgc ctctttatcc tcagaaagaa aagttgaaat
    12601 ggtaaacgga atttctgttt cacttaaaat ataaccagaa ggtgcttcga tctcttttaa
    12661 tcgataactt cctgttttca acccggaaat tgaaaaagcg ccatttttat cggaaatcag
    12721 gtgaagcgca tctgattcgt tctttgtcca cttgtatccg ttggctgttt gctggaggta
    12781 atttcctgct ttgtttttaa taaggaatac tgcgccagct aatcgtttat ctggtttatt
    12841 tgtctcgatt ttgacaaatt gcttactccc tgtatataca gagactttct ttgtactgac
    12901 accaaaacca aaatccagtg ttccgttgtt gttgatttcc ttgttcgcct gtgctgtact
    12961 gcttagctgc atctgataag aaatggtcag tttttttcca gcatattttt ccaacgaagg
    13021 gatcgaaaat aaaacatcaa atccgtgagg tttcttgtgt atgacaaagc cttctgtcag
    13081 cttttctcca ttcgatgaaa tcgttaaact attaggtaaa aacgttaatg cttcatccgc
    13141 actatctgac aattcgaact tttgatagtc aaggatattt acaggaattg tcgtatgcaa
    13201 ggaataagtg attttttcac caatcgtaaa atcatttcta ggctcttcta ataccttctc
    13261 aaaaggtgga tcagggtagt cgttttcttc atttttagga tacaaatgga tagttgaaag
    13321 tttttgattg ttttgtccat gtacaggaag aacaactacc atattctctg ccttttcttt
    13381 gacgacttct ggtactttgg attcaatgaa aagatacgct ttatctcttt tttcttgatc
    13441 tttagcggcc agagaaaaag aagcgatacc atcttcgttg ttaagagttg tagttgttgc
    13501 ttctgcggta aacataccgg aagacgcacc gttttttgcg atctctgctt gtgcttcttc
    13561 taccgttttg cccttttccc gtagatggta aaaagaatct gtgacatcat aaacttggaa
    13621 tgtgacacca tttaatcctc gatacgtttg taataaagct ttttcttgtc cgtcatttgg
    13681 atgatttttc ggcagttgcc cgtttgggaa aagcaatttg tgtaaagtaa tctgaaccat
    13741 ttctgtttct gtttctgttg ctacctgagt aaaagctggt ttaaatagta acaagaagag
    13801 acacatacta agccaaccaa gttttttcat atttagctgc cccctctttc ttttttcaaa
    13861 aaaagatacc aaatagaaaa cgcacaacca atcatcccta ctagatagat tcctaaacgg
    13921 ccaattcctc ccgtttcagg taatggtact tttgcctgat tcgtgatgtc taaagaaatc
    13981 tggttgtttt tggctcctgg tgacagaaca gattcatgat cttgtccatc cacttgaatt
    14041 gacccatctt cgtgtataac tatagtaact ggctctttta gaccttggta tccttctggt
    14101 gtaaaagttt cggtcagcgt ataagttcca ggttttaaat tttcgaatag aaaggtatct
    14161 gtttcttgtc catcttttgg cgattctaag tccatttctg gtccctgcag tctgaatttt
    14221 gctcctttta atgtctgtcc gttgtcttct tttttgtgta ccgttagatc aaacgctttt
    14281 agtcgatttt gatgagtgag cgtccataca ttatttgtca tctcggtatt ttttcccgtg
    14341 taaatgattt ttccatattt atcgatttgg aattcataat ttcccggcga agtatcatat
    14401 ccggcaggac cagctgtttc aacgactcga tatttaccag gtgtgagtga atcaaaactg
    14461 gcaagacctt tttcattcgt tgtttggctg tcaattggct gataagtacc atttgcttct
    14521 tttttctgta gggaaaatgc tgctccttta agatttatct ctttgtccgt cccttgcatc
    14581 gcatacttac gtactgctac aggaacttca acaaaaggat tttcaatagt caactggatc
    14641 gtatcatcgg aagtagtgac tgtttttcca tcaatggtta ccgtaccatc agaagcgatc
    14701 ttgatttccc aagtagtctt tttgcttaat ccatgccctt ctggagcttt tgtttctgtc
    14761 agcgtatagg tcatttcttt ttgcaatttg acattttctg gaagagaata ggttccgtcg
    14821 ccatgatctg ttagtaaagt atcaatagaa tctcctgtta atttgaaaac agcgccaata
    14881 agatcctttt cacctgtaga ggaatttttc gttattttca agtttaacgg tgtgaattgt
    14941 ttagtatttt tccatgtcat tgcatctatt tgttgagaat cgtatcctgg tacaggtaat
    15001 tctttgattg tttggtaact gaatgcttga ccttgattat tgtattgagg tagtgataat
    15061 atctcttgat aactttctcc gctatttgca gataatttgt caatgtctgc acgttcccac
    15121 gtatttgttg tatctttagc tggtttaatg attcgaatat atccgttttt ccaagctgca
    15181 gcatttgtcg tatgttcccg ttgaatctca aaagtaactt gatctggacg atcagctaga
    15241 ttgttgtcaa attcttccca taactttttg atgtgaagac tgactccggg agctttagca
    15301 gatggtatac cgaattcagc taattcattg gtatcaatgt ttggctggaa agttgtcctg
    15361 ccgttcattt gataccagaa atttggatgg aagtcctcat tttctgtttg gattctcact
    15421 tggtaatgga tttggatttc ttggtctttt cctaaataga tctgattgct cttgatggta
    15481 tttccttcta tggaaataga tggagtgacc gttgtaggac ttgtccccac actcttgact
    15541 gaaagtgtac caggctgata aatgaatggt tctgcgattg gatcatttat ttgtccattg
    15601 cttacagttg ctgagatctg tacagctttt ttggctaggt attcagagat atctgttgca
    15661 tgatcagctg attcatagta aagatcgcct ttttcatctg atgaaaccat ttgtcgcata
    15721 cgagactcta cttctgcttt tgagagacca gctgccggat cgctttgaag ttggatgcca
    15781 agaccatgta tttcgattcc tcgttctttg agtgccatcg cttctccgat ggttgcgata
    15841 aacgtactgt cgattcttct ggatagattg ttttggtcag gtgcatcata gattcttgag
    15901 attagagaag tatttcccgg ccgatcttgc gtattagaaa actgagttcc gtaataattg
    15961 ctgcttgatt gtgcgtgtac ccgctgtact ttataggaaa atgttggtac accatccgtc
    16021 agcaaaacga tcactttttt atgtccattt ggaacggata gcatgcttcc tgcatctctt
    16081 agtgcttttt gtgtaaaagt accaccattt gtccgtgaag gtgtaatgga ttttacttga
    16141 tttttcactg aatcaaatga acccatctgt actgcaccgt tactgtagct atatccttcg
    16201 cttgagtagc cgacatatcc catattgatt ttgtctgtga taccgctatc tgctaaagta
    16261 tcgacaaaac gatcgacacc aatctttact tcaccgatcc gattattgtc gttcatactt
    16321 cctgaccagt ctacgaccaa tacgagatca agaggcgtga tatctttttg tacatttcca
    16381 cgagcattca aataaacatc aaacaatccg ggtgtacttg tttcctttgc atactttcgt
    16441 atcgcatagt ctgcttgatt accggttcct ccatattcga tatacgaatg ggtccgatca
    16501 ttaggatctc cattccaaga atttatacca tcccattgat ttgttccgtt tttattgcct
    16561 tgatgatcaa gaacatttgt atttcctgta ggttgccaac tggctttagg ataagtgccc
    16621 tgatcatctg ttgtatattc tgtaggaatc gtttgattag atggcacact cacagctggc
    16681 aaggataatg taggcaatgt aaatgggctg acagaatttt cgttttcttt tgatgattct
    16741 tcttctattt cgtctggctt tggtactgac acatctgtat ctttcttatt ttctgtctca
    16801 tcaataatgt catattcttt attatcgacg atcagcttgt ttgcctggct gtggtaaagt
    16861 gctggatcga ttggaaaact cagatcgata gtttgtttag tgtttgatga gatttccaac
    16921 gtaattttcc cgctatttac ctgataagca tagccatctc cttcttttct ttccacatca
    16981 cttaagtaat tttcgactag accaatttct ttttctatct tttcagcact ggtgttattc
    17041 gcatttagct tgatgttcag tgcttttttt ccagactgat ccgaaatgac ttcagctgaa
    17101 attgtttcta aaactgttgg atcatctgta gtgtctgcta ttgcagataa tggcacaaag
    17161 tttgataaac tcaatattat cagcatgaaa ataactttca gtttcttccc tgtggtcgtc
    17221 atttttcccc tcctttttct ttttttctgt tttgacgtga atagtgaaaa ttattaaaat
    17281 aaacaggcgt tacataattt tatttatttt aatatgataa ttattatacg aagggcgcta
    17341 aagggaatca caccaatttt cataccaatt ggtttcattt atgaagttga ttccttcgat
    17401 taatgagcgt ttcattgaaa gaaaagggtt gagggagaaa aacatatgat caggttgttg
    17461 gaacgaaact atagaaagat ggaaaaaatc attcgaattc tgtccatttc tgacaagtgg
    17521 atgactaaaa aagaacttgc caaacgaatt ggtagttcag aatctacatt tgtaaggtat
    17581 aatcgaagag atcaaaatcc gctggggaac ggatgtaacg attcaatctt cacaaaaatt
    17641 ggggtatcgt cttgaacatt tgaatgtacc agcttattta aatgttctga tggaaatgtc
    17701 gcaaagttct acaaacagtc gtttattaaa tgagattatt gtcaatccgg gtaaaacgat
    17761 tgagtattat tgtgaaaaaa tttccatcag ccggtcttct tttacacgta agttgaaaca
    17821 atgcaatcaa attttagaaa gctatttatt aaaagtgatc gttgaccaag gttttcagtt
    17881 aactagcctt aaaagtgagc tccagttgcg tatctttgtt acctttttct ttttaagtta
    17941 ctacggaaga cgcacgttgc catttccaat cgaaaaaaag aagatcaaag aaattatggt
    18001 caagaataat tgtcagatga atttgtttca ggaagaaagc ccatatgagc aatctttctt
    18061 tattatgtat tttgttgtgc atctcatgag agaatcccaa ggaactccat ttgaatggaa
    18121 agctggagac tcttatgtac agttgataaa tatcgataaa aaagacttct taatcttgaa
    18181 aaatctctta ggaaaattga agtacagcag ctatataaaa gtagtgaact attttgtcaa
    18241 tacgattttt tcagaatttt cggagaaaga aaaaaatgaa atcagtgagc agatacgaaa
    18301 aaatatgtcc tactgttcgt tttcatccgc tgattgcaaa gaaaaaaacg aagaatatgt
    18361 tgttcaatta ttaacgcaaa tttatttttt ctcccgtatt ttcccatacg atacgactca
    18421 tttgacgatc cgtgcaactt actttgcaca gcagatgcaa caccgccaga tacgtctata
    18481 tgctggattt cgtgcagaac ttcaatttta ttccactcta ctgaatcaga atctgattta
    18541 ttatttatct agctatatct tttggatgct tatcggtaat cctgaaattc accattatac
    18601 ttctgataaa aaaatactga ttatcagcga cttaagtctt cgacatagtc aatatattga
    18661 agaatatatc agtgatattc ttgctgtgca taaaattcac tctgagacaa ctgctattac
    18721 tgaagatcag ctgtcgaaat acaatcttct cgagtatgat ctgatcgtta cgaatcaacc
    18781 cattttgaat gcccatgttc ctcatatatt gattgatgat agtgtgtcat tcgcaaatga
    18841 agaagaactc atccgcttat tcgagttatg aataatcaaa aaacagctat gtataaacca
    18901 ccctgataaa aatttcagga caaatacaca tagctgtttc tttttattgt attccttcag
    18961 caatccaacg agatttatag cgaaagtctt ttaacaactc ttcttttgtc caattatttg
    19021 caatgagatc cgtcaaagtg ttcattacga gggtcatgga aaagtatagg aaactaactg
    19081 cttcttccga cgattgaatg gagaaatgat tgattcttaa taattccagc catttttcgt
    19141 tcattggaga atcagccgat agttctctac gtttggttgt ctgctgatca tttcgctggg
    19201 ttaacaagta taacctttgc caatagatac tttcgtgatc taagtcgcag caccactcta
    19261 aatatttttc gatccccaaa aagaaatgtt gtttgttttc gctaatgaat tttaagatat
    19321 cttgatggac tatgtgagaa ctgcttttga tcgtatacaa ataagcatct tccaaatctt
    19381 gaaaatattt ataaaaagca ccgcgcgaca tccccatctt gtcaacgatt tctgagactt
    19441 tgacttggct gatgtgctgt gagcaaaata tctccagtaa taggtcatcg attctctgtt
    19501 tctttgcgtt cgataaattg aaaaaagttt cttttggcat ccacatctct cctttatctc
    19561 tgattatacg tggatagccc ttcattgtca tgaaggattc attccttctt tttctcttct
    19621 tctgtcaagt acccatcttc cattcgataa acgcgatcac tccattgaat catacggaca
    19681 tcatgagtaa ccataatagt cgctttttgt ttctcatgag cttctttaac tagtaatttg
    19741 acgacttcat atgcatgatc tgtatccaaa ctagctgttg gttcgtctgc taagatcaag
    19801 cttggctcat tatataaagc gcgagcaatt gccactctct gtctttctcc accagaaagg
    19861 tctttaggat aactattttt aagtgactgg atatctaaag attgcagcaa ggaatcgatt
    19921 tttgttgaat cttctttttt tgaagtaact tggtcaacta gttcaaattg ttcctttacc
    19981 gttaaaaaag gaatcaaatt agagctttgg agaataaatc ctatttcttt aaagcgtaaa
    20041 tctgctcgtt ttttttctgg aagctcagtt agtgagtgac cgttgatcac tatttctccg
    20101 gaagtcggtg tttgcaatcc tcctgaaatg gtaaggaaag tacttttacc tgaaccagaa
    20161 ggaccaatga tgctgacgaa ttctccttcc tttacataaa aatcaattgc tttcaaagct
    20221 gagacctttg tatgaccaga accaaatgtt ttggtaactt ttttcatcgt taatattttt
    20281 ttcattttta ttaacctcct attgctgtaa ttgggtctac tttggttatc gtacgtatcg
    20341 aaaacaatcc gcctagcatt gcgacaatga tcaaaatccc actatatagc aaccattgtg
    20401 accaaaaaac agcaaaaggc atcgcgcttg gtaaaatcag actagtcaaa taagcaaaca
    20461 aaagagcaag cagaacgcct accaccccaa caataaagga ctgtgctact aaagatttag
    20521 cgatgaagaa atttttgatc ccttgtgctt tcattactcc aaaaatagca gtcttctgaa
    20581 gtgtcatcac gtacatgaaa ataccgacca cggcagcaac cactaagaac aaaaagtata
    20641 tcatcgcatt taaggtcata ttttgggcag aatagccagg aatactttca atgaatgtcc
    20701 caatagttaa taactgtaga cccttcgatg ctttttcttt cgaaatttta gctgaatcct
    20761 ttattacgat cccattgatc ggctgttctt cttcagaagc aaacggctgt tgtccatact
    20821 tcaaagcagt ccacgtatct agggacgcat agatgacggg agaaactgtg taataagttt
    20881 caggaaagat accgacaatc gtcaaaggat cgtcgtaact gccaattttg atcgtatctc
    20941 caattttata gcctgaatca gccagatttt gagagatgat gatttcattc tttgttttaa
    21001 attcatgccc tttcgtgagt tttggtaata aaaatgcttc tttcgttgtg ccgaaaactg
    21061 taacattttc tttgtttttt cctttgattg ctccgctgta caatccgatt ggtgctttct
    21121 ctcctccttc aatgtatttc agatctcctc ttgttaattg tgaagctgca aatacttgat
    21181 ttgcatcctc cgacaaaaca atctcttgtg cgtcccaatc atcgattgct tttttaaact
    21241 cttctgaaag tccattcgct agtcctgaca acatgaatac gacatacgca atcaagaaca
    21301 taataccgac gatcaagcca tatcgtaatt tagaatagcg aatttctttg atagctagaa
    21361 acatttgttt ttcctcccta tgatagattg atagtgacaa aatgtcactt gttgaatagt
    21421 gtaactctaa agtgacaatt tgtcacttgt gttgtttttt tcttatcaat aaattgtcta
    21481 agacatcttt cgataaaacc ttaacatgag tcataaaaaa tttatttaag ccttatttat
    21541 gctttccatg ataaactaaa gtgaccaaat caatgaggtg ggaaaatgat taaactatta
    21601 gtagtagaag acgataaagt attatccaat aatataaaag aaatactcgc tgcaatcggc
    21661 gagataacac aagtttatga tggtagtgaa ggactgttcg agttggaaag tggagtttat
    21721 gatcttgcaa tcttggattt gatgatgccg gaaatgaatg gatatgaagt gttagcaaaa
    21781 atacggaaag aaaaaataca gactccagta ttgattttga ctgcaaaaga tagtttggaa
    21841 gataagattg aaggatttga acgaggtgca gatgattatc taacaaaacc tttctatcga
    21901 gaagaactga tcatgcgcgt gaaagcatta ttgaaacgct cgctaggtct ctttgatgaa
    21961 aatgttctga agtataagga tatcagttgt gatttaaaaa gcaatgaagt cttgtataaa
    22021 gaacaagttt tgcccataca aggaaaagag tttgaattgc tcgtttattt tttacaaaat
    22081 aagggaatca ttttgacaaa agagcagata tttgaccgga tctggggatt tgattctgat
    22141 acgacgatta cagttattga agtttatatg agcaacttac gaaaacatct gcgaagtact
    22201 ggattggata aagaaatcaa aaccttacgt aatgtcggtt atatactgca aagggtgtga
    22261 tgcaatgaat ggagatatta cacgaaagca acgtagtcgc ttttttgcga caaatgtagc
    22321 agcatttgct tttatctttt ttcttttggg attcattact ttacagatat taaaccaatc
    22381 tgcatacaga gaaacagatc tgtcattaga gaaaataaat tttgattctc gaacagtaca
    22441 attagagata caaagatatc agcaaggcga tcccttttta aacccgactc aaacggaaca
    22501 aaacagaaca aacatggaac agccattaat ggaaccatca aatgaccgtt ttaacactca
    22561 agtgatcttg tggtctaaaa atggtgagat attgaataaa gcagctattg gtgggcgttt
    22621 caaccaaatc aaagaattaa aaatggatac gaaaaatctg aataccatcc aaaatattga
    22681 attaaatgaa gacagtggct catctgccct ctctttccgt tcgattacga aaaaagcgga
    22741 gacgaatcaa gatggcgttg cctacatcca aattttagaa aatacaaatc aaatcaagaa
    22801 ttcattagcg acttttcgca cgattatgat tttgtgtatg attgtttttt ggattctctc
    22861 tattggtatc agttattact tgtctagtct aagcatgcgc cctattattc tttcttggag
    22921 aagacaaaaa gaatttgttg agaatgcttc tcatgaattg cgcacaccgt taacgattat
    22981 tcaaaatagt ttggaacatc tttttaccaa gcctaatcat actattattg aagaatccga
    23041 aagcatcgct caagcattgt cagagacgag gcgcctcact ggattgactt cggatttgct
    23101 gacaatcgct cggaatgatt ctgatcagca gctgctttca aagcaaatga tcaatacaca
    23161 agaatatatc gaacaacttg ttaaaccatt tcaagagatg gccatcatag atggaaaaga
    23221 gtttattctc cataacgatg caacattaga agtaccaatt gatgaaaaaa aaatccatca
    23281 agttttggtt attttgctgg ataatgcatt aaaatatacg aatccagaag ataagatcat
    23341 tttggattca tctgttaacc ataaagaatg gctgattcac gtaaagaata ctggcccttc
    23401 tatcagtgaa gaagatcaag caaggatttt tgatcgattt tatcgggaag atcaatctcg
    23461 ggcgaaagag actggcggat acgggcttgg cttggcaatt gcaaaacagg taatcgaaca
    23521 gcatcatgga cagatttctg tatccaatta tcttccacaa ggagtcgatt ttaaagtcca
    23581 attgccgttg aagcctaaaa aataatgctt atccctaaaa aagggctgtg acaaaaatct
    23641 tgtcacagcc cttttttgtt gcgaataaac ggtgttccag aagtagcttc ttcggaaata
    23701 agccgaaatt tctttaagct gaccacttct gtcacaacct ctttagctta cgcttacgat
    23761 tttttattgc ggtcttcaat gtgtacatca ccgcttgtgt caatatccaa ttcttctcgg
    23821 ctaacatctt ctgtcacttt ttcaacatct tcatgttctt ctttatgaat cccaacttct
    23881 tcacgaataa ctgtatgttt gcttacatct acttgctctt ctttgattgg gatagtaatc
    23941 gtgtcatctt ccaatttttc gtctgttccc tgtgaagatt gatctgttac tggtttgcgt
    24001 tcgatgacga tttcttcacg tttgaccggt acttctaccg tttcagtatc gttgaccaca
    24061 tgtttgtgga tgtcgacttc tccagttgtc acatcatgtg tatttacatc taatttttct
    24121 tcttttagtt gaattgtatc atcatctaga tttggtttgc gatcgatgtc ttcagtcttg
    24181 cttgtaccca ttgtatcagt ctcgccaggt acgtccatcg gatcagttcc tggtgtcata
    24241 ttcaatggat ccgttgtatt ttgaaagcct gtcgtgccac ctacgtccat tggatctgtt
    24301 ccagtgccag tttctaatcc agtccccatt gtgcttgctg ggctaacagt atcttgtgta
    24361 tccattgtat cttctgttgt ttctggctga cgatagcctt ttactgtgat gacaaatttt
    24421 ccatcagaaa tatctcctct atattgatat aaaggatcat tttctggtgt agccgtctca
    24481 gaatcatagg tatcaaaaga aaaagtatct tttatttttt cccataaaga acggtcttct
    24541 tcaccatcca tccgattttc atctgtttca acatctatac cagacaatcc gtcaaatcct
    24601 agtctagatg ctgcttcatc agtagtataa ataacgatat catctcgttc atacccttcg
    24661 ttacgcaacc gttcaattac tgataatgct tcttccctcg tactatagct tccgatgacc
    24721 gttaaatttt tctcttccat gtaaattcct cctagcaaat agatttatga ttggtatatt
    24781 gttacttata aatttattct ataggagacg attgttttct acaaatattt agattggaat
    24841 ttgattaaaa caatttaatt gaaatttgaa aacatttatg ttaatgaaag tcatattcta
    24901 ataaaatgtc atttgtttct atatgaattt ttatgaaaaa tttcatataa tttccactcg
    24961 ttgtgatggt ttaatttatc caatccatca ataagcaaac aacttatata aaaaaggatt
    25021 aattctcaat ataattgctc ctaccataga ataaatcttc atgtaaagta atgaagtacc
    25081 aactatttct aatacttctt taagaattat cccaacaata tcgttagaca aaccattatt
    25141 gaataaatgg agagccaatc gattctgaaa aaatgttttc taatttttcg gaaataaaag
    25201 aaagagcctc ctgccattag aacgaaccaa atccatttca ttgctcatga agtaaccaca
    25261 tagctaaaaa gaggataaat caattaaaag atcaaaagaa tgactgcact aataaaataa
    25321 ctaaaaatgt atcttcttac ttcatatctt ttagctagta cttagttaaa aatttgcttc
    25381 ctaagatcaa gacaaactgt ctatcttcat ttgatgaaat gcggtaaaat atagaaaatg
    25441 aacactattg gagggaattt gtaatggaca gcaaaactag aaaacaactg caagaaaagt
    25501 taaagcaacg tacacacttg ctcccttccg tctttcaaca gtttttagaa gaaaatcgtt
    25561 cttccctttc attaggcagt cgctatgaat acgcaaaaga ttttcatctg tttactgatt
    25621 atttgagaaa agtattttct gaagaagtgg atgatcagct gattatccat ttagaaaaac
    25681 aagattatca gaatttctta gctaaaatct atcgacatac tcgttcgttc caaactacag
    25741 cgaaccaaga aacggagcaa ttgtttgaaa atagctatta cgggatttca aggaagcaat
    25801 attcattaaa tcatttttta cgatttttgt atcaaaaagg actgattgaa gaagagattt
    25861 ctcttttggg tacaagttta ccggaaacaa ccaaagcagc tccgcgatat atcgatgcag
    25921 aacttttcaa agattttgag catttgttta tcccgattga aggctttcaa acaagcagag
    25981 aagctagctt tgaagaaaag aatagaccga ggaaccttgc aattactgcc attcttctgt
    26041 attgcggatt aaagatccat gaagtagtag aacttaaacg taaagatgta tctttgacca
    26101 agcagattct taatctgaat agaaaagaaa acagactgaa taaagtacca ataccaaaag
    26161 aagcgatgcc atttctggag aactatttta agttaacagc acaaaatacg gacgaaaatt
    26221 cttttgtttt tcgttcctca catgatcagc aaatttctcc tcggactatt cgccaaattt
    26281 tgagcaaaat tacagtatat aaaaacgtat cgccagaact atgcagaaaa acatatcgtt
    26341 attatgcaga actatattta gatgatgctg acgcggtaaa ttatttatgt ggtaatcgat
    26401 acctctcatc ccattctttt caagatatct gggaaaagat ggttgatttt tcttatcacg
    26461 aattagcggc attcgttcgg gtttcttcca tataaaacaa atgtatgatc tttttttcac
    26521 aataaactat gttattatat aaaggattat gttacgatta tcttgaattt gtatattact
    26581 taacaaaaga taatggagtg tgaatgatgg agaccataac gtattcccct ttgaacttat
    26641 ttacgaattt tcaagaagct gcagctaact tttccgagac cccgattatc tttgatgagc
    26701 cactttcagc tttcccagaa ttaggacttg aaacaactta caaaaaatgc tgcgaaagtg
    26761 tgttgaaacg ggcttatcaa ttggctcatc ttggagtgaa atccggagac aaagttatta
    26821 tttataagag ttccgctttt gacacatacc ttctagctgt ttctgtgtct taccttggtg
    26881 cagtgcctgt catgacttct tatcatctac caacaacaac aatggaagta tttatcgatc
    26941 gtttagaaga ccctttcatt ttatttgatg atgagacaaa aaagcgagtg agagaaattt
    27001 caaatggaac aaaatcaaaa cagatt
//
LOCUS       DAFBSV010000032        26894 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.033, whole genome shotgun sequence.
ACCESSION   DAFBSV010000032 DAFBSV010000000
VERSION     DAFBSV010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26894
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.033"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(39..1145)
                     /locus_tag="LLB18_001273"
     CDS             complement(39..1145)
                     /locus_tag="LLB18_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBK5244284.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRTRYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            1355..2356
                     /gene="ccpA"
                     /locus_tag="LLB18_001274"
     CDS             1355..2356
                     /gene="ccpA"
                     /locus_tag="LLB18_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HBK5244285.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLADRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEGFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(2693..5038)
                     /locus_tag="LLB18_001275"
     CDS             complement(2693..5038)
                     /locus_tag="LLB18_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBK5244286.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            5317..6219
                     /locus_tag="LLB18_001276"
     CDS             5317..6219
                     /locus_tag="LLB18_001276"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBK5244287.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            6432..8207
                     /locus_tag="LLB18_001277"
     CDS             6432..8207
                     /locus_tag="LLB18_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBK5244288.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(8273..9859)
                     /locus_tag="LLB18_001278"
     CDS             complement(8273..9859)
                     /locus_tag="LLB18_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HBK5244289.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQEMVEEIE"
     gene            10110..10334
                     /locus_tag="LLB18_001279"
     CDS             10110..10334
                     /locus_tag="LLB18_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HBK5244290.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            10475..12226
                     /locus_tag="LLB18_001280"
     CDS             10475..12226
                     /locus_tag="LLB18_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK5244291.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSVKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIISAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            12226..14010
                     /locus_tag="LLB18_001281"
     CDS             12226..14010
                     /locus_tag="LLB18_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5244292.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     VLTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            14336..15187
                     /locus_tag="LLB18_001282"
     CDS             14336..15187
                     /locus_tag="LLB18_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBK5244293.1"
                     /translation="MLIEKVLNNNVVITRDERDREMIVMGKGLAFKKKVGDPILDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVHLNDSVYISLTDHLY
                     TAIERQKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GAKSEDGEVSEELFQVVQKKYKDTFGCVEKIADFLTGAFDYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            15284..17164
                     /locus_tag="LLB18_001283"
     CDS             15284..17164
                     /locus_tag="LLB18_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK5244294.1"
                     /translation="MGKYQELAENIVKNIGGKENIRSLTHCVTRLRFKLKEENKAKDD
                     VLKKMEGIVTIMKSGGQYQVVIGNHVPDVYAEVLTVAGISDEVEEEVSSSSNLFNRLI
                     DILSGCFQPFLGALAAAGMVKGLNALFLFLKFYTEGSGTYIMLNGIGDAIFYFMPVIL
                     GYTAAKKFHLNPMVGLVIGAALCYPTVQGAALQSGFPDGSPAPYSLLGLPAYETFLGI
                     PWVGSSYTSSVVPVIFIIAFAGQVQKIAKKWIPAVVQTFLVPFSVLLIALPAGFLIIG
                     PIVSILTDLLSTGFQALMDFSPAVYGAVLGFLWQVLVIFGLHWSIIPLAIMQLAQNGW
                     SQMLVGVYGASFAQTAVVLAMYFKFKDQKMKALCMPAVISGIFGVTEPAIYGITLPKK
                     KPFIYSMIGGAISGIYLMASGTISYTMGGLGIFGVVNYITETDASGMFQAFIGIAIAS
                     VIGFSLTFFFWKDEAGETDAIQKKSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGRGI
                     LIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESLVQ
                     QGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGETVGPDDALITA
                     LT"
     gene            complement(17204..18106)
                     /locus_tag="LLB18_001284"
     CDS             complement(17204..18106)
                     /locus_tag="LLB18_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBK5244295.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKYLLLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENKVILRTAEILKQNHVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            18337..19740
                     /locus_tag="LLB18_001285"
     CDS             18337..19740
                     /locus_tag="LLB18_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBK5244296.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALNDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            19740..21173
                     /locus_tag="LLB18_001286"
     CDS             19740..21173
                     /locus_tag="LLB18_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBK5244297.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDVFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQVKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            21318..22244
                     /gene="trxB"
                     /locus_tag="LLB18_001287"
     CDS             21318..22244
                     /gene="trxB"
                     /locus_tag="LLB18_001287"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBK5244298.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            22458..24185
                     /locus_tag="LLB18_001288"
     CDS             22458..24185
                     /locus_tag="LLB18_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBK5244299.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEEAKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            24200..24550
                     /locus_tag="LLB18_001289"
     CDS             24200..24550
                     /locus_tag="LLB18_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBK5244300.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKSKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(24642..25502)
                     /locus_tag="LLB18_001290"
     CDS             complement(24642..25502)
                     /locus_tag="LLB18_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBK5244301.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLKQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            25594..26022
                     /locus_tag="LLB18_001291"
     CDS             25594..26022
                     /locus_tag="LLB18_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBK5244302.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            26184..26360
                     /locus_tag="LLB18_001292"
     CDS             26184..26360
                     /locus_tag="LLB18_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBK5244303.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            26387..26833
                     /locus_tag="LLB18_001293"
     CDS             26387..26833
                     /locus_tag="LLB18_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBK5244304.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
BASE COUNT         8508 a         4796 c         5747 g         7843 t
ORIGIN      
        1 aaaaggtggg agcggactag ctctcacctt ttttactctt atttttctaa aacaagtaat
       61 tcttttggtg tagtcgtgaa tggcacacag ccatcgcttg tcacatatac acagtcttcg
      121 atacgtaccc ctactttttc aggaatatag attcctggtt caagagagaa gcacatccct
      181 tcttcgatta ctaagtcatt tccttctaca agggaaggga attcgtggac ggttgttccg
      241 atcccgtgac ctaaacggtg attgaaatat tcgccgtagc catagctgtt gatcacgttt
      301 cgtgcgattt gatcaagttc acctgctgtc acacctggac ggacggcttc ttgtgcggca
      361 agctgtgctt caagagtgat gttgtagatt ttttcttgga agtcggttgg tttttgataa
      421 gcaattgtac gagtagcatc actgcaatag ccattccaaa caacgccaag atcgaataac
      481 acaagttcat tcggtgaaat cttcgtattt cctggtgtac catgagggct tgcagcattt
      541 gctcctgcaa ggactaatgt gtcgaaagac atttgtgaaa caccttgttt tttcaattgg
      601 tattcaattt ctgcaatgat cgcttgttca gtcacgcctt ctttcactgc tttaaagcca
      661 atctcaaatg caacatcggc ccatttacca gcttcgatca gtttgtcttt ttcctctaga
      721 gttttgatca gttgtagacg ttggatgatg gaagttagat cagtgtaaga atccgttccc
      781 gtcaagatat cagagatagc atcgaagcgc tcgacagtca aggcgttctt ttcaatccct
      841 acattgccag gctgaccata gcgagtacga agttcttttc cgatgatctc ccaagggttt
      901 tcgctgtcta aatagccgcg gacatcatac gcccaactac tgttttgagc atcttcaact
      961 tccaaagcag gagtgaaaag gaaaggatct tgttcaagag ggataaaaag agctagtaca
     1021 cgctcatgag gatcactttc gtatccggaa aagtaagcga tgtggccagg gtcgctgata
     1081 taagccaatt cgacttggtg ttgtgccatc cattgacgta gttcattgat ttttacgtta
     1141 ttcatttggc aacctacttt ctaaattaat tttgtattca ataattgtac cactgattta
     1201 ttaaaagacc aacgttctaa aaactgaaaa aagtaaaaat tttcatgaaa acagagataa
     1261 aacggttgca attcttgaga ttatttgata ttctatttta gaaatgtaag acgtattttc
     1321 agaaaacata taaaatatga atgggagaac acaaatggaa aagcaaacaa tcactatcta
     1381 tgatgtagcg agagaggcaa atgtttcgat ggctactgtt tcacgtgtcg taaatggcaa
     1441 tccaaacgtt aaaccagcaa caagaaaaaa agtcttggaa gtcatcgatc gcttggatta
     1501 tcgtccaaac gcagttgcgc gtggcttggc aagtaagaaa acaacaacag ttggggtaat
     1561 catccctgat gtcagcaata tgttctttgc ttctttagca cgtggtatcg atgatgtggc
     1621 aacaatgtac aaatacaata ttatcttagc aaattcagat ggcaacgacc aaaaagaagt
     1681 caatgtattg aataacttac tggctaagca agtggacggc gtgatcttca tgggtcacca
     1741 tatcacagac gaaatccgtg gagaattttc acgttcaaaa actcctgttg tattagctgg
     1801 ctctattgat ccagatgaac aagtaggtag cgtaaacatt gattatgtat ccgcaacaaa
     1861 agatgcagta aataaattgg caaaaagcgg caataaaaaa atcgcttttg tcagtggtgc
     1921 gttgatcgat cctatcaatg gacaaaatcg tctgaaaggc tataaagaag cattaagcga
     1981 aaataaccta ccatatagcg aaggattgat ctttgaagca caatacaact tcaaagatgg
     2041 tctatctcta gccgatcgga tccataatag cggtgcaaca gctgtctatg tttcagatga
     2101 tgaattagcc atcggtattt tggatggttt attagatcgt ggcgtgaaag taccggaagg
     2161 attcgaaatc atcacaagta acaattcact actgacagaa gtagctcgtc ctcgtttaac
     2221 aagtatcaca caaccattat acgatttagg ggcggtatct atgcgcctat tgacgaaaat
     2281 gatgaataaa gaagaagtcg aagaaaaaac gattatcttg ccttatggaa tcgaagaaaa
     2341 aggatctaca aaataataaa aggacaacca ttcagaggtt gtgagcctgc cgtttaactc
     2401 tgcgttacaa ggagcaattt caaaaaacag catttcatgt ttgatgaata ttgtgactcg
     2461 tgattcggag ttggcaggag aacaccgttt attcgggaaa aggggttatg acaaaatttt
     2521 gttataatcc tttttttgtg tcttaaaaaa gagagaaagt ggttgaaatt acatttatcg
     2581 tatataaaac aatccgtgta tagatgctgc attttgttca ccaccatcaa aaaaataagg
     2641 gactgtgaca atactattgt cacaatctct tattactgtg tattctatta aatcaatcat
     2701 ctttctcatc tgattctttg gttgcttgat tcgctcttgc ataagctgaa gcggtgttcc
     2761 agtaatctgt atagttttca tcggtaccgc caacgccaaa tttaaaggcg cttttcttcg
     2821 gtccattttt cgcccatagc gattcaactg tttttccagg tgtttggatg gattttttat
     2881 tgacagtaac ttttccaggt gtttgaccag taaatccaga tacttttttc ttcatcacat
     2941 cagatgataa ttcgaatttc tcatcagtgc caaaaatgtc aggttttgct tggtaagctt
     3001 gattgatcag attggcaaga taattagccg aacgtatcct tgctttgctg tccattccag
     3061 tattgtcatc gtgccctgcc cagctactga tggtaataga cggagtagag acaattagcc
     3121 atgaatctcg gtattcattg gtagaaccag tttttccgac ccaatctgct tttcctagat
     3181 ttccgtttaa gcttgagatg gcatctttga atggtgtagt gatttttgca ttgatcacac
     3241 tgcgcatcat gtcattcatg atcgatgccg ttgcttccga atagatccgg acagagttgc
     3301 tttcgtgttt ataaattaca tttcctgcgt tatctgtgat ggaatcgatg atatagcctt
     3361 cttcatagac gccgccgttt gctaaagcct gaaatccatt ggtctgttga agcgtcgtga
     3421 catctactgt acctaaagga gcagattcaa cgccccaatt gtcatttgcc gggtagttca
     3481 tctttgccaa gtagtgctcg taagcatatt gtttcgatcc accggaattc aacacatctt
     3541 gatataagtg ataagccggg atattgttgg accattctag tgactcacgg acggtttgga
     3601 aggtgttcga tccttcgtta gtagcattga cgattttctc gccagcattt tctccttctt
     3661 gccaagttgt tgcataatct gatacacggg attctgatcc gataagcccc atgtcgattg
     3721 caggtccata aacaagaact ggtttgattg atgagccagc ttgacgttct gtatcgaagg
     3781 catggttatt ttgattctga ctgtaattcc gtccgccaac gaatccgtag atgcggccag
     3841 ttctgttatc catcaataca tttccggttt ctacttgact gccagcacca tcatctaaca
     3901 tgtatccata attttctacg ccattttgca atgcagcata gacatcttta tcgattgtcg
     3961 aatggattgt atatccttta ttttggattg tttgctgtgc cttttgataa taagcgtcac
     4021 tgaccgatga atcagacata tcagcgttgt ctttttcagc caattgttgt gcaatgattc
     4081 ttgttgcttc attcatcaca gtataataca agaattctct gtcagtctgt tctgcgattt
     4141 gttgtggtag aaagtctttt gtaaggtcat aggcttttgc ttcttcgtat tgttctttcg
     4201 taatttggcc ttcacgatac atactgaata aaacaaaatc ttttctggca aggccggcag
     4261 aaagatcttc ttttagcgca cctgtgttcg tgtatggact atacgtgatc gggctttggg
     4321 gtaatccagc gatataagca gcttgcggca gcgtcacatc ttttgcatct acaccaaaga
     4381 ttcctcttgc agcttcctgg actccagcaa tgttttgtcc cttattatta cgaccaaatg
     4441 gtgagacatt caaatacgta gcaatgatct catcttttga aaagtatttt tctacttgtg
     4501 cagaaagaat gatctcgttt gctttacgtt tgaatgttgt ttcatctgta aggatctgct
     4561 gtttgactaa ttgctgtgtc aaagttgatc caccagaaga gccaatacca gtagcttcag
     4621 atactaacgc tcgtaaaaca gctttaggaa cgtaaccttg gtgtttatcg aagtattcat
     4681 cctctgtgct gataattgca gttttcaata aaggtgaaat tttatcagat gaaatagtcg
     4741 tgcgcatcag atctgtctgg atttttgata tctctgtatt atctgcataa acaatctttg
     4801 acgtttctgt aatgtttcct agttctgtct gcagtgcttt tttagtcggc aattgtgtgt
     4861 cttcgacgag ataggcaaaa tagccagcgc ctattccaat acctagagct gcgaacatca
     4921 aaagaagaac agtaataaaa acagtcaatg attgaaaaac tctaaaaata atcttaggaa
     4981 caaaccattt ttcttttttt cttctattct gtttttttcg agtatttttg cgtggcaaaa
     5041 gggtcacctc aactaatggt tttatttcgc taattatagc aaataataga acaaaaaaac
     5101 agacaaggct gtttttggca ggaatttctt ttttaaagga gttaaaacgt gagaaaatga
     5161 tcttttttat aaaagagttc ttaagctttt ctttagagaa aatttcagtt actatggaga
     5221 acagggcaaa gaaaaatcaa tcattttctt tgtatatcat cttaccaata tataggaatt
     5281 gttagtaaca attgcctttc aaggaggaat ccatccatgt tattaggctc acacgtcagc
     5341 atgagcggaa agaaaatgct gttaggagca gcagaagaag cagccagtta tggatcttcg
     5401 acttttatga tctatacagg cgcccctcaa aacactagaa gaaaagccat cgaagagatg
     5461 aatattgatg ccggaaaagc gtacatggca gaaaacggtc taacaaatat cgtcgttcat
     5521 gccccttata tcattaattt ggggaatacg atcaaaccag aaatgtttcc ttttgccgtc
     5581 caatttctga gagaagagat tgttcgtgcg gaagctttag gcgctactca aattacactt
     5641 cacccaggtg ctcatgtagg ggcaggaaca gaagccggaa ttgctagaat tattgaaggc
     5701 ttgaatgaag ttttgacaaa agaacagacg gcacaaatcg ctttggagac aatggcaggt
     5761 aaaggtacgg aaatcggtcg aacatttgag gaattagcgc aaatcatcga tggagtaaaa
     5821 ttgaatgaaa aattatccgt tacttttgac acctgtcata cgaatgatgc cggttataat
     5881 attaaagaag acttttcagg tgtaatggaa gagtttgata agatcatcgg gttagatcgg
     5941 cttaaagtac tccatatcaa tgattctaaa aatccgcaag gttcgcataa agaccgacac
     6001 gccaatattg gttttggaac aatcggattc gacacgctga ataagatcgt ccatgatcca
     6061 atgtttgaca atatttcgaa aatcttggaa actccctatg tcggcaaaga taaaaagaaa
     6121 gcttacgcac catatggaaa agaaatcgcc atgttcaaag cacaaatatt cgatccagaa
     6181 gtgtttcctg agttattagc agaagaagtg atactctaag attttctatc tgacagcagc
     6241 aaaaaaggac caggcacatt gccttgtcct tttttgttta agaaacaaag gagtgctttt
     6301 tgcagtcttt ttcatcatgc atcttctccc ccctcttttt aaatttagac aaacagggta
     6361 tactggtaga aaagtaaaaa aacgaaaagt ttcacaagca agtggcaaaa cgtgattgga
     6421 aggacgaaaa gatgctgaac actttaaaac ccttgatcaa ccaactaaaa aagaaacata
     6481 catactttat tcttggcata gccctattat ttacaattat tcgtttgtat ttatatagta
     6541 aagcaatcta tggaacagac atgtcggcaa cctatgatga ccagctgctg attcgctatg
     6601 ctcaaaatat tttggacggt aaatggctag gggagtatac gactacaaca ctttccaaag
     6661 gaatctccta cagcttattt ttagtacttg cacataaact gcatctttct tatgcagttt
     6721 tgttcggcat gttcagtatt tttgccagta tattggttgc actcgcgttt aaaccgatcg
     6781 tgaagaacaa gtatcttctt ttaagtttct atttttattt tttgttttct ccgattagtt
     6841 ttacacatga atattccact cgaacgtatc gtaatgccct cgtgattccg gctgttgaga
     6901 tcattatcgc ttgtttacta gctatttatt accgcaaata cggttctagc agaaaattgc
     6961 tgccatggtt tttagggctt tctgtcgctt ttcctttctt ttggttcatt cgcgaagatt
     7021 ctatctggct tcttcctttt actgtagtag ctttgggtat cagtttcgtc cagatcttgc
     7081 tagggcaaga cttttctttc aaagaagtaa agaagttaaa aaaacgactc tttcttctct
     7141 cgaaacggga atggctgaaa ctttcattgt ttttacttcc tatagttggc ttttccatcg
     7201 tctatcagtg gatcgaatat aaaaatgaga caacatacgg tattgcaacc atcaatgacc
     7261 gttccagtgg agaatttgga cgtttgatga aacaactgat ccgaatagat gatgaaacga
     7321 acttgaataa agaaaacagt gagatatggg tctcacatgc tgcactaaat aaagcattag
     7381 ccgcatctcc tacattccat actgtttcta cccgtattga cgaattatat acgactcacg
     7441 cgtggactca aggtggaaaa gtaaaagaat tacccggaga tatcatcttt tgggcattgc
     7501 gagatgtggt aagcgaatct ggttattacc aaaacaatgc aaaagaaacc aatgattttt
     7561 ggaaaaaagt caaccaagaa ttagaagaag cctatcacaa gggaaccatc aaaaagaaaa
     7621 aagagttcta tctgatggga tcaggagatg gaaagacgat gagtgatcta ccaatcgtat
     7681 tcgatttcct tcaatcagga tacgcttatg catggcgata taaagatttc catcaaggag
     7741 gaaattatag tttcggaacg caagaacaag tcaaacaggc tcaagaatta ttaaaccttc
     7801 cgctaatgga gaattggatc gatagtaatg aaccgagaac acctaatttc caattaacaa
     7861 aatcagcaaa agtcgcgaat gtcatcataa aaatttacca agttctggct attcccgtgc
     7921 tgattgcttc aatagcaggg atattactta tgatactagg aaccgtattt gcaaaagctg
     7981 atcgtgccta ttatagttcc tctttgattg tggtcaccgg attaatactg acacaattgg
     8041 tttttctttt cggtgtctcg tggttttgtt cttatgcgcc agaaaaaaag gattattttt
     8101 taagtgtcta cactggcgca ggcgtgccgt taacgcaatt catcgtagta acaagcatgc
     8161 tagttttcag taaattaaat ctgaaaaaag ctttatcttc taaataaaaa gacccttggt
     8221 agctagattt ttaacctaac tatcaagggt ctttgtgtgg aaaaatcagt ttttattcga
     8281 tttcttctac catttcctgc aaacgctgtt catatttttt gtttccttta tataaatcac
     8341 caatcgtcca tgccaacagg aggaggacaa gaacaatgat tacataagcg atgtgatcag
     8401 ccaatgctag ttgagcggaa gtggcttgct cgccgaagaa actttcgatc tgtcctggta
     8461 atcctcgtaa gttcaagtaa gttagactaa tcacagagaa ccagccaaga agttttacga
     8521 tgaatgaatt tttaaatcgg ctacccatct ccgcttggct gttggtcatc atcagtaaag
     8581 ggatcatcga aaacggcaac gcaaaagcca agaacacctg ggattcattc attaagttat
     8641 tcaaagcggt atgttcttcg atcgttcctt ttgtacttgt aaacaaaaca caaatcaata
     8701 caggaatcac agaaagcaat cgtgtgacca gtcttcttag ccaaatcggg atacgcatat
     8761 ggatgaatcc ttccatgatg acttgaccgg tcaacgtacc agtaatagta gagttctggc
     8821 cagaagcaag aagtgctaca gcaaataaag tggacaagat accagatttt gctacagcaa
     8881 tcaagatacc attgctcata gctgatggat cagataaagc ttcatacaga ccaaaaaagg
     8941 aaggatcttg aacagaaccg gttttgaaga cagcgacacc cataatcaat agcagcgcat
     9001 tgactagaaa agccatcgac aattggatat tagagtccca agtagaaaaa cgtacagctt
     9061 gtgctacatc ttcttcgtct tggtgatcga tcttccgagt ttgtgaaact gctgaatgta
     9121 gatataagtt atgtggcatg actgttgcgc caataatccc taatgctcca gttagcggag
     9181 tttcgccacc aatgacaggt gagtcggaga atgtatggct gttagggata aagccagcaa
     9241 ataaactgtg ccaatctggg ttagacaagc caacttgata gacaaaaacg aataaaatga
     9301 cgaaaatcaa gcagacaacc agtgcttcga tcttacgaaa cccgactttt gtcagtagta
     9361 agagaacgaa aacatctaat acagtaataa agacggcaat caccaatgga atatcaaaaa
     9421 gtaagtagag ggcgattgct gcaccaatga cttctgcaat atctgttgcc ataatggcta
     9481 attcagtcaa gatccataaa atgacaccca atgtcttact tgtgcgtgct cggattgctt
     9541 gggccaaatc catttgggtc acgattccta attttgctgc catatactgt aaaagcatag
     9601 caatcagact agacatcaaa ataactgaca tcaataaata ttggaaattt tgtcctccgg
     9661 tgatcgaagt agaccagtta cccgggtcca tatacccaac tgctactaac gcaccaggtc
     9721 cagagtaagc aagaagtgtt ttaaaaaaac ttttcccctt tggtacatcc actgttccat
     9781 ttacttcagc taaagataaa ccatttgtat gttcaataag tcgatgctta tgaaattgtt
     9841 tgttggattg attattcaag aaaaaaccac ctttcctatt tatctacgat tacattctac
     9901 acctcaaaaa gaaaaaatta aagaaaaaga ttcggtatgc ctaatttttt ttcgtggcgt
     9961 gtcttgctag atgacgaaag aaattttgtt ctcctctaaa aaaaccacta ttttttgcat
    10021 gaaactaaag aatacgcctt tcttttttca ataaacttta gtaaaataag tcattgagag
    10081 caattcggaa atagaaagga gagatttata tgttatcaac aggtattgtc gtacttattg
    10141 ctattattgc tttgctaatc ggcgcagtag gtggcttttt cctagcgcgt aaatatatga
    10201 aagactattt agaaaaaaat cctcccgtta atgaggacat gttgcgatca atgatgatgt
    10261 caatggggca aaaaccatct gagaagaaaa ttcgccagat gatgcagcaa atgaagaacc
    10321 aagggaaaaa ataggttctg acccaacgac tttttacggg ctgatttttt cagtccgttt
    10381 tttatttcgt aatttgttag actattcaga ttattcagca aaaagacaag cacagacaat
    10441 cctaggctct tgataaagac aaaggaggag taaaatgtcg atttttagaa agttaggctg
    10501 gttttttcgt caggaaaaga aacattattt aattggggtt ttctcgctat tcgcagtggc
    10561 cttggtacag ttagttcctc caaaagtgat tgggatcatc attgatgaga ttgccgataa
    10621 aaatttatca gtaaagatca ttttcgggtg gatcttccta ttgattatcg ctgctttttt
    10681 acaatatctt tttcgttata tctggcggac gaatatttgg ggaagtgcag ctcggttgga
    10741 gaaagaactt cggcagcagt tattcaaaca ttttacagaa atggacaatc tcttttacca
    10801 aaaatatcgg actggggatt tgatggctca tgcaacgaat gatttgaatg cgatccagaa
    10861 tgtagcagga gctggtatct tgacctttgc agattcagtg attacgggcg gaacaacgat
    10921 cattgcgatg attttgttta ttgattggcg cttaacactg attgcgctga ttcctctgcc
    10981 tttgctggcc gtcacttcac gagtgctggg gtcgaaactc catgatgctt ttcgtgattc
    11041 gcaagaagct ttttctagta tcaatgataa gacacaagaa agtatcactg ggatcaaagt
    11101 cattaaaaca tttggacaag aaaaagaaga tctagcggat tttgaagaaa agattgaaga
    11161 tgcaattatt aaaaacaaac gagtcaattt tttagactcc ttatttgatc cattcattac
    11221 cttgattatc ggtctgtctt atgttgcaac aattatttta ggtggaaagt atgtcttgga
    11281 aggcacgatc tcgatcgggc agatggtctc atttattagt tatatcggta tgcttgtttg
    11341 gccgatgttt gcgattggtc gattgttcaa cgtattggaa agaggaaatg cttcttatga
    11401 tcgcgtcaat gaacttttgc atgaaaaaac gcatatcgtg gaacaactgg gtgcagtgca
    11461 gaccccggca aaaggcgagc tgaatgtagc tatttcctct tttaattatc cgaaagaaga
    11521 atcaccagca ttagaacaaa tcaagtttgc aatccaagaa ggagaaacat taggtattgt
    11581 tgggaaaact ggtgcgggaa aaacgacgat catcaaatta ctgatgcgtg aatacgatga
    11641 ttatcaaggg aaaatccaat ttggcggacg ttcgatcaaa gaatattcat tgaatgcttt
    11701 attaggatca atcggctatg tgcctcagga tcacttcttg ttttcgatga ccattcgaga
    11761 taatatccgt ttttctaatc caaaactttc agaagaagaa gtagagcatg cggcttcttt
    11821 agcatttatc aacaatgaaa tcaaggaatt accaaaaggt tatgatacct tagttggaga
    11881 acgtggagtc tctttatctg gcggacagaa acaaaggatt tcgattgctc gagcattgat
    11941 caaaaatcct gaattattaa tattagatga tgcactttct gcagtagatg ccaaaacaga
    12001 agaagctatc ttgcataatt taaaagaaat aagaaaagag aaaacaacta tcatttcagc
    12061 tcaccgttta agtagcgtga tgcatgcaaa agaaatcatt gttgtcgatc aagggaaaat
    12121 cattgaacga ggaacccatc atgagctgct tgcactaggc ggctggtatg aacaaatgtg
    12181 ggagaaacag caattagaag cgaagataga aggaggcgag gcctgatgga tgaaaattat
    12241 caatcggaat ggacaaaatc gattccactt aaagaacaga aaaagatcat caaacgactg
    12301 atgaagttcg ccaaaccttt tagaagaacg ttcatcgttg ctatcttatt tgcgtttgct
    12361 ctgtctgtga tcaatgtcct attgccaagg atcatccaaa cttttatgga tgatcatctg
    12421 gctaaacagt cggctacgac acaagttatt ttgttttttg ctggtatgta cttatttgga
    12481 gtcatagtaa aaagtatcat ttggtttttc caatggtatt tgtattccat ggcttcattg
    12541 aagacctatc agtatattag ggtaaaatta tttgaaaagc tgcatacact aggtatgcgt
    12601 tattttgatc agacaccggc aggatcaacc gtttctcgag tgacgaatga cacagaaacg
    12661 ctatttgaat tttggtacgt ctttttgatg gtattgactg ggatctttgc agtcgtttct
    12721 tcattcattg ccatgtttca aatcaatgga gaaattgcct tgtggacttt ggtgttcttg
    12781 ccaattttag gaatagtcat ctggtattac cagaaattta gttctcgtat ttaccggaat
    12841 atgcgggaaa aattaagtca gctgaatacg aaattgaatg aatcgatttc cggcatgcgt
    12901 attatccagc agtttcgcca agaagctcgt ttagctaaag aatttgaaca agtgaacaat
    12961 gagtatttag acacgcgtta tgcgatgatc aaaacaaatt cgattctgtt aagtccgatc
    13021 atcaattttc tatatgcatt ggcgattgcg ttggtgttga ctttgtttgg gatcgatgcg
    13081 ttgcattctc ccgtagaagt tggactgatc tatgcattta cgacctatgt ccagggattt
    13141 tttaatccaa tgtctcaaat gatggacttt ttgagcatct tcacagatgg gatggttgct
    13201 ggtagtcgta tcttgaagat tatggataca gaagaatatg caccacaaca aaaccctgga
    13261 gcagatcaaa tgattacttc aggtaagatt gagtttcgca atgtaagctt ttcttatgat
    13321 ggagagcaca atgtattaaa caatatctct tttgttgcta atccgggaga gaccgttgca
    13381 ttagtgggac acaccggaag tgggaaaagc tcgatcatca atgtgttgat gcggttttac
    13441 gaattttatg aaggtcagat attgattgat gatcatgaca ttcgagaata tccaatggaa
    13501 gagttacgta agaaaatggg gctggtcttg caagatgctt tcttgtttta tggggatatc
    13561 gcaggaaata ttcggatgat gaatccagct atcacagacg aacagatacg ccatgcggct
    13621 gagtttgttc aagcaaacaa attcatcgat gaattaccaa aaggatatca ctcaaaagtg
    13681 atcgaacatg gtgccagcta ttctagtgga caacgacagc tgatcacttt tgcgcgaaca
    13741 atcgtgactg atcctaaaat tctagtattg gatgaagcaa cagcaaatat cgatactgaa
    13801 acagaaggat tgatccaaga aggattggcg aaaatgcgac aaggacggac aacgattgcg
    13861 attgcccatc ggctgtcaac gattcgagat gcagaattga ttttagtttt agacaaaggt
    13921 catatagtag aacgcgggaa tcatgaaaca cttctagcgc aaaatggttt gtatgcagat
    13981 atgtacaaac tgcaaagcag tggtatataa aagatgttgt gacagtagca ttttgaccta
    14041 agcactagag tgaaaataaa acatagcttc ccatattttt catctgtgag agttagtgtc
    14101 gtagttacca gatttaaaaa agacgacgtc agctagtcag aagtgcctaa tagcccctaa
    14161 gaaagcgttg acaaaatcgt ttgctttcga taatataaag aaaacgatac aacttggata
    14221 gtgattgcct gatgcaagct aaacctaatg agtctcccat ggtttcatgg acggcttttt
    14281 gggtttttct ttttgttttg gatacagccc tatatatcat ggaaaggagc aaaacatgct
    14341 gattgagaaa gtactgaata acaacgtcgt aataacaagg gatgaaagag atcgggaaat
    14401 gattgtgatg ggaaaaggat tggcattcaa aaagaaggtg ggtgacccga ttcttgattc
    14461 atgcatcgac aaaaaatttc agttgacaaa tgacggactt tcacaacagt tccaagaatt
    14521 ggcacaagcg attcctcttg agtacttaga aatttcttgt gaaatcattg aatatacaaa
    14581 agaggctctg caagtccatt taaatgattc tgtgtatatt tcattgacgg atcacttgta
    14641 tacagctatc gaacgtcaaa aaatggggat ctttgtgcca aatgtattgc tgtatgatat
    14701 caaacaactg tttcctaaag agtatgccat tgggaaaaaa acagtgaaga aaatctcgga
    14761 taaataccac atcaagttat cagaagacga agccggattt atcgcattgc atttagtcaa
    14821 tgcacaaggc attcaaagcc agcaagacaa tacctacctg tttaccacaa caatacagga
    14881 tattttaaat atcgtccgct attactataa gattacattt gatgaagatt cagtccactt
    14941 ttttcgattc gtcacacacc tgcgtttttt tctgacacgt gttctagatg gagcgaaatc
    15001 agaagatgga gaagtttctg aggaattgtt ccaagttgtt caaaaaaaat ataaggatac
    15061 gtttggttgc gttgagaaaa tagcagactt tttaaccggg gctttcgact accagatgtc
    15121 cacggatgaa aaaatgtatt taacgatcca tactgcgcgt ttagtgcatg agaatcgttg
    15181 taaataaata aaaaaggagg acaaattaac aagaacgtat gaaaataagg gtagtgacat
    15241 tcagttggct aaaccttcca ctaattaatt ggagggaata gaaatgggaa aataccagga
    15301 attagcagaa aacatcgtaa agaatatcgg aggaaaagaa aatatccgta gcttgacaca
    15361 ctgtgtgacg cgacttcgtt tcaaactaaa ggaggaaaat aaagcaaagg atgatgtttt
    15421 gaaaaagatg gaagggatag tcaccatcat gaaaagcggc gggcaatatc aagttgtaat
    15481 cgggaatcat gtgccagatg tctatgcaga agtactgaca gtagccggga tttccgatga
    15541 agtagaagaa gaggtttctt caagtagtaa tctgttcaat cgattaatcg acatattaag
    15601 tggctgtttc cagccttttt taggtgcttt agctgcagcg ggaatggtca aaggattaaa
    15661 tgctttgttc ttgtttctca aattttatac tgaaggatcg ggtacgtaca tcatgctgaa
    15721 tgggataggg gatgcaattt tttatttcat gccagtgatc ttagggtaca cagcagcgaa
    15781 aaaatttcat ctgaatccga tggtggggct cgtgattggt gcagcacttt gttatccgac
    15841 tgtacaagga gcagcactac aaagtggttt ccctgatggc agtcctgcgc cttatagctt
    15901 gctgggtctt ccggcttatg aaacattttt gggtatccca tgggtgggca gcagttatac
    15961 cagtagcgtc gtacctgtta tcttcattat cgcatttgcc ggacaagtcc aaaaaattgc
    16021 caagaaatgg attcctgcag tcgtccagac ctttttggtt cctttttctg tgttattaat
    16081 cgcacttcct gctggctttt tgattatcgg tccgattgtc agtatactga cagatctatt
    16141 aagcacggga ttccaagcat tgatggactt ttctccagct gtgtatggtg cagttctagg
    16201 gtttctttgg caagtactgg tgattttcgg acttcattgg agtattatcc ctcttgcgat
    16261 tatgcagcta gcgcaaaatg ggtggagtca gatgttagta ggcgtttatg gcgcgagttt
    16321 tgcacagaca gcagtggtat tggcgatgta tttcaagttc aaggatcaaa aaatgaaggc
    16381 gctttgcatg ccagctgtga tttcaggaat cttcggcgta acagaaccgg ctatttatgg
    16441 aatcacctta ccgaagaaga agccatttat ttactcgatg attggtggtg ccatttcagg
    16501 aatctatttg atggcatctg gaacaatcag ctacacaatg ggcggattag ggatttttgg
    16561 ggtggtaaac tacatcacgg aaacagacgc cagtggtatg tttcaagcgt ttatcggcat
    16621 tgctattgct tcggtaatcg ggttttcgct gacttttttc ttttggaagg atgaagcagg
    16681 tgaaacagat gctatacaga aaaaatcagg taaagaaatt gtaaaaacac cgatacaagg
    16741 acaaatcgct ccactaaatg cagcgaagga tgcagctttt gcacaaggaa cactaggtcg
    16801 aggaatcttg atctaccctg aaaaaggaga agtacgtgcc ccttttgacg gaacagtcat
    16861 gaccctgttc ccgacgaaac atgcaattgg aatggtttct gaaacagggc tggaattgct
    16921 gattcatgtc ggattggata ctgtgcagtt ggaagggaaa tattttgaaa gcttagtgca
    16981 gcaaggagaa agagtgaaac aaggcgatct gttgctacgc ttcgacaaaa agaaaatcga
    17041 aaaggaagga tacagtttag aaacacctgt gatcgtcacc aattacacgg attatttgga
    17101 tattttggaa aaccaagggg agacggtcgg gccagacgat gcacttatca ccgcactgac
    17161 ctgaacggtt aggtgaagaa tggaataggc ttaactattc tttttattcc acttctttat
    17221 tttcaaaatt gaaaggctct ttcatgatgg ctgagctgat agggcgttta tcgaattttt
    17281 gaccgacaga aattagatgg actaaattct gttgataatt ttctgcaaaa acacaactat
    17341 ataacacgtc tagaagataa caaattgatg tattgatcgt aaaattacca atttttgaat
    17401 acagtcgctc gcgtgtcgta agtcgcaaag cggctgtact cattgcagat agcgttgaat
    17461 caccgatact ggtcaaagct aaaattggaa catgattttg tttcaatatt tctgcggtac
    17521 gaagaatcac tttattttca cccgtataag aaatcaggat cccgcacata tcgctcgtgc
    17581 aattgtacgc ttcatagaat gattcaccaa aagtggtgac aattgtgaca tccattttga
    17641 tgcgcttcat tttcagcatg aaatcttgag aaatcaaagt attcgagtta ctggcgaaga
    17701 tcacgatttt ttttgcctgg agcagtaaat acttggcttt ttgcagttgg tcatgatgaa
    17761 tgagagaaag tgtatcttga atcgtcatct gttctaaaga agccatttta tttgcgatcg
    17821 tcataatacc gtctgtggtg gaaaaaggaa gattcgcatc tacgtcttga aaattccctt
    17881 caagataggc tgtttcagct aaaaaagcat tacgaaaact gacccagcca tcaaaaccca
    17941 ttttttttgc tacacggatg agtgtagacg ggtggacata gcatcgctca gcgatctctt
    18001 ggatggtcat ttcgccaagt gctggagaat cgcttaagag aaactggatc acttcatttt
    18061 ctgaaggaga aaaggagatt tctttgattt tttcacgtaa taacatgtag ttaccttctt
    18121 cttatttttt tacgtaaatt ataacttttt tgaaaatgtt ttgtaaacgg atttatacta
    18181 tataacttaa aatagacttt ttttgacaag atatttacaa aaatccacta gaaaacagta
    18241 acttttgtaa atgttactgg aaagaaacgg atttctattg tttgttttgt ttacaaaaaa
    18301 gataatgaaa gtgtaaaaaa gtaaaggagt gagaacatgg caaaaggaat caaaatcgct
    18361 acgattggtg gaggcagcag ttacacccct gagttgatgg aaggatttat caaaagatat
    18421 gaggaattac cgatacgaga aatctggctc gtagatgtag aagaaggaaa agaaaagctt
    18481 gagatcgtta gtcagatgtc tcagcgtatg tgggatgctt ctccgtatga agtcaaaatc
    18541 tatgcaactc tggatcggga agaagcattg aatgatgcgg attttgttac gactcagttt
    18601 cgtgtcggtc aattagatgc acgaatcaaa gacgagcgga tccctagtta ttatgggatg
    18661 attgggcaag aaacaaatgg tgctggcggg atattcaaag cttttcgtac cgttccagtg
    18721 gtcttggcaa tcgttgaaga catgaagcgt ttatgtccaa atgcttggct gatcaatttc
    18781 gcgaacccaa gtgggatggt gacagaagca gttatcagat atggcaaatg ggataaagtg
    18841 attggattat gcaatgtgcc agtaatggcg atgatgacag aaccagcaat gcttggcaag
    18901 aaaaaagaag agctgatcta caagtttgcc ggtctaaatc atttccattg gcacaaagta
    18961 gcagataata aaggaaatga ccgcacggca gaattgattg atcgtttata cgatgaagac
    19021 aatggattgc cgaaaaatat ctttgatatc ccgtttttca aagaacaatt aaaacaaatg
    19081 aatatgatcc cttgtggcta ccaccgctat tactaccgtg aagaagaaat gctggaacat
    19141 gctttagaag aatatcaaac gattggtaca agagcgcagc aagtgaaaga aacagaagca
    19201 gagctatttg aattatacaa agatccagaa ttagaccata aacctgaaca attgcaaaaa
    19261 cgaggtggcg cttattattc agacgctgcc tgtgaaacga ttgcttcaat ctatggaaat
    19321 aaagaaacac agatcgtggt atctacaaag aatgatggag ctgttcctga cctgccggca
    19381 gattgtgtag tagaagtcac tgcctatgtt ggcgcacaag gagcgagaaa tgtagcgttt
    19441 ggttctcttc ctgctgctga aagaggctgg ttgcaagtaa tgaagaatat ggaattgctg
    19501 acgatcgaag cagctgtgac tggtgattat gggacagctt tacaggcgtt tacgatcaat
    19561 ccgcttatac gatcaggaaa gacagcaaaa cggatcatgg atgagttgtt tattgcacac
    19621 cagcagtatt taccgcaatt caaggaaaca atcagccgat taaaagaaga aggaatcgaa
    19681 gttcaagatg aactggcaag agaattatca ggtaatacac atataatgga ggaagtataa
    19741 tgggattcag aaaagatttt ttatggggcg gtgctacagc agccaatcaa tgtgagggcg
    19801 gttatgatga aggtggacgc ggactagcaa acgtagatgt tgtgccaatc ggaaaagacc
    19861 gttttcctgt tatcaccgga aagaaaaaaa tgtttgaatt tgatgaggat catttttatc
    19921 cagcaaaaat tgcaatcgat atgtatcatc gttataaaga agatattgct ttgtttgcag
    19981 aaatggggtt caagacttat cgaatgtcca tcgcctggag tcgtattttt ccaatggggg
    20041 atgaaaaaga gccgaatgaa gctggcttga aattttatga ggatgtcttt aaagaatgcc
    20101 aaaagcacgg aatcgagcca cttgtgacga ttacgcattt tgattgtcca atgcatttga
    20161 tcaaagaata cggtgcgtgg cgttccagag aactcgttgg tttttatgaa aatctgtgtc
    20221 gagtcatctt caatcgatat aaaggacttg tcaaatactg gctgacattc aatgagatca
    20281 atatgatcct tcatgcacca ttcatgggag caggactgta ctttgaagaa ggagaaaacg
    20341 aagaacaagt caaatatcaa gcggcacatc atgagttggt tgcaagtgcc atcgcaacga
    20401 agattgctca tgaagtagat ccggagaaca aagtaggctg tatgctggca gcaggagcat
    20461 attatccata cacttgcaat cctgaagatg tttgggcttc tagaaaatca gatcgagaaa
    20521 attatttctt cattgatgtt cagtcacgag gagaataccc agcttatgca ttgaaagaaa
    20581 tggaacgaaa tggcattcag atcgaaatgg aaccagggga tgccgcattg ctgaaagaac
    20641 atactgttga ttttatctct ttttcttatt attcttcccg agtttcgact accgacaacg
    20701 aactcttgga acagactgca ggaaatatct ttgcttctgt caaaaatcca tatctgcaag
    20761 caagtgaatg ggggtggcaa attgatccat taggcttgag aataacgatg aatgatattt
    20821 atgatcgtta tcaaaaacca ttatttattg tagaaaacgg cttaggtgca gtcgatacgc
    20881 cagatgagaa tggttatgtg gaagatgatt accgaatcga ttacctggca gcgcatatcc
    20941 aggcgatgaa ggatgcagta gaactagacg gagtcgatct attaggctat acgacttggg
    21001 gatgtattga tttagtatca gctggtaccg gtgagatgaa gaaaagatac ggattcattt
    21061 atgtcgatcg tgataaccaa ggaaatggca cattagcccg ttcaaagaaa aaatcattca
    21121 actggtataa aaaagtaatt gattcaaatg gagaaaatct ttcgaacgat tgatcaatga
    21181 tttataaaag tctattgttt ttcagcggat ttttcgagta taataaagct attcgagaaa
    21241 cgcaagcaga acaatagact ttttttcgca ttggctgtaa agtatgctta cttgattaag
    21301 taaaggagaa tctacatatg tatgatgtaa tcgttattgg cgcaggtcct gctgggatga
    21361 ctgctgcttt atatgcttca cgttcaaact tatccgtatt gatgatcgaa caaggtgccc
    21421 ctggcggcca aatgaacaat acggcagaaa tcgaaaatta tcctggattc gattcgatca
    21481 tgggccccga tctagcttat aagatgtatg aaagtgtctc aagatttggg acagaaaatg
    21541 cttatggaat cgttcaagat atcaaggatc acggcagcca taaagaagtc atctgtgaag
    21601 ataaaagtta cgaaggaaaa acagtcatta tcgcaacagg ctgtatccac cgtaaattag
    21661 gcgtacctgg cgaggaagaa tttgctggac gaggcgtttc ttactgtgca gtctgtgatg
    21721 gtgcgttttt ccgtaacaaa cgtctagtag tcatcggggg tggggactca gcagtagaag
    21781 aagccatcta tttgacacaa tttgcttctg aagtagtgat cgtccaccgt agagatgaat
    21841 tacgtgcaca aaagatcatc caagaccgtg catttgcaaa tgaaaaaatt tcctttatgt
    21901 gggatacagt cgttgacgaa atcgttggaa acgaaatggt agtgacaggt gtgaaagcac
    21961 gtaatgtcaa aaccggcaat gaatttgatt tagcagcaga cggagtattc atctatgttg
    22021 gactggatcc attaactgca ccttttagag aagcaggttt gacgaacgaa gctggctgga
    22081 ttccaacaga caacgaaatg aaaacgaata tgccaggcgt ttttgccatc ggagatgttc
    22141 gtgaaaaaga tttgcgacaa atcactacag ctgttggtga cggcggtatt gctggacaac
    22201 aagtgtataa atacttggaa tctttagaag aaacaactgc ataagtttaa aaagagtaga
    22261 agaacgggtt caattgttct tttactcttt tttttcgcgt gaaatttact gaatctgatt
    22321 tatgcgaaca cgtccaacac cttttgataa aagaatcctt tcttgattta agcgtttttt
    22381 ggtcctcata ctttcatatc taataagtga atgctatact tattaagaac catatttcag
    22441 aaagaggtgt tattttcatg tcttgggaac aagtgtatga acaatgggta catgaagaaa
    22501 atttagaaga aaacttaaaa aaacaattaa atgatctggg tgaagatcct gaaaaacttg
    22561 aagatgcttt ttatgcaccg ttggaattcg gtactgcagg catgcgggga atcttaggac
    22621 ctgggatcaa tcgaatgaac atctatacgg taagacaagc aacagaagga ctagcacgtt
    22681 tcatggatac acaaggtgaa gaagcaaaac gccgaggtgt cgctattgct tatgactcac
    22741 gccatcagtc accagaattt gcaatggaag cagccaaaac actggcacat cacaatatcc
    22801 cgtcttatgt attcgaaagt ctgcgtccaa caccagagct ttcttttgca gttcgtcatt
    22861 tgaagacgtt tgcgggaatc atggtaactg catctcacaa cccagcggct tacaatggat
    22921 ataaagtcta cggagaagat ggcggacaaa tgcctcctgc agacgcagat gcattgacga
    22981 aatatgtccg tgaagtcagc aatccgctaa aagtcgaagt attatctgac gaagaagcta
    23041 aacatagcgg gttgatcacg atcatcggag aagaagtgga cgctgcttat ctagaagaaa
    23101 tcaaagcagt gacgattgat cgtgaattgg tagaaacaat ggggaaagat ttgaaacttg
    23161 tgtacacgcc acttcatgga acagggaaaa tgttgggcga acgtgcgttg aaacaagctg
    23221 gattcgaaca attcgtacta gttcccgaac aagctgtggc agatccagat ttcactacgg
    23281 tcaaatcgcc aaatccagaa gaacattcag cttttgaata tgctatacga cttggagaaa
    23341 aagaaggagc tgacttgctg attgcaacag atcctgatgc agaccgttta ggcgcagcgg
    23401 ttcgtttgcc agatggttct tatgaagtat tgactgggaa ccaaatcggg gcattgtttg
    23461 ctcaatatat tttggaagca catcaatcaa gaggcacttt accagaaaac gcagcggtat
    23521 tgaaatcaat cgtttccagc gaattgccta cagcaattgc ggaacactac ggtgctacca
    23581 tgttcaatgt gttgacaggg tttaaattca ttgctgaaaa aatccaacaa ttcgaagaag
    23641 accattcaca tacttttatg tttggattcg aagaaagtta tggttattta gttaaacctt
    23701 ttgttcgcga taaagacgcg atccaagcat tgcttttatt agcagaagta gcagcttact
    23761 ataaaaaaca aggcaaaacg ttgtatgacg gcttgcaaac gatttttgaa acctatggct
    23821 attttgcaga aaaaacgatt tctgtgacaa tgagcggaca agaaggttct gcgaaaatct
    23881 ctgctttgat ggaaaaattc cgtaaagaag caccgacaga atttgccgga gcaaaagtta
    23941 ttcaaacaga agactttaaa gaattgacga gaacagaccg tgaaggaaac gtagaaaaac
    24001 taacaacacc gccatccgac gtattgaaat atacattgga agaaaatggc tggattgcta
    24061 tccgcccttc aggaactgag ccgaaaatca agttttatat tggtgtaaaa ggaagctcta
    24121 cagaagacgc agccgaaaaa gtagcctctt atgaagcgat tatcaaaaag atgacagaag
    24181 aataaaaaac ttgagactga tggaaaaagt ggtaaacttt agaagtcagt cttttttcaa
    24241 gttggaggtg aatggattgc cagacacgca aaaatcaaaa gtagagaaag tcagtcaatt
    24301 attcaaaatg ttgagtgatc ccactcgtct taaaattctg ctatatctga aagacgggga
    24361 acaaaatgtg acagcaatca cccaagcagt ggaaatggag cagtctgctg tatcgcatca
    24421 actacgttta ttaagagaaa atcatgtcgt caagtctcat cgcgagggaa aagcgatttt
    24481 gtatagtctt gatgattctc atgtactgga tattttgaac cagacactca aacatgtgga
    24541 acatcaataa cgataggtgc aaatagataa acactggagt gtgacaacga aatttcttcg
    24601 ttgtcacact ccagtgtttt ttaagaaaaa gacaaaaatg attaatcgct tttttctgtt
    24661 gtttcagttc cataataact atgatcttct aggtctaaag cattcaaaat aagcgaagcc
    24721 gtttcttcaa tagataaaga tgccacattg atcactacac atcctagttt ttcataaaga
    24781 tcattcgcaa aatcgagttc agctctaatt ttttcgatat cggaataagc agtatcaggg
    24841 tttaatccgt aagagcgcat ccgttcttta cggatattat ttaaaatatc tgggttattc
    24901 gttagtccca cgattttttt aggatcgatc tcccaaagct gtttgggaat atgtgcttgt
    24961 gggatcaaag gtaaattggc aacttttaaa tttttgttag ctaaaaacaa gctcaaaggc
    25021 gttttggaag ttcgggatac gcctagcaaa acgacatctg cttctaaaaa accacgagga
    25081 tctttcccat catcgtattt tacagcaaat tccattgctt tgatccgttt gaaatagttc
    25141 tcattcaata aatggagggc accaggttgc cgaattggct tgataccggt taaacgttca
    25201 atttctgata tcggtggcgt catcacatca aaactaaata attgatgttc ttcacaaaaa
    25261 gaacgtgtta tctcgatcag ttcttgattg attaatgtat gcaggacaag tgctttttct
    25321 tctaatgcat cttgcaatgc ctgctttaat gttttttcat ctgtcacgaa cgttctgcgg
    25381 aataggttga actcaacggt aggatactga gccatagtag cttgcgctag ttttgtcgca
    25441 gtttctccag cagagtcgga gatgacaaaa aaagtaacga tttctgtaga atcggaagac
    25501 atggataaaa cctcacttgc atttttttta tgtttattat accatactct agaatgcgta
    25561 cttcgtaatc attttgattt ggaggaataa gtcatgaaaa aacagacatt gatcgaacaa
    25621 tcattagaaa cattgaaaaa taacggtttt aaatatacta aaaaaagaga agcattgtta
    25681 acttatttag tgaagcgtaa ccgctacgta tctgctaaag aagtttttga ctatatgaat
    25741 caggaattca aaggggtaag ttatgatacg atttatcgga atctccatga ttttgcagag
    25801 atcgatttac tggaagaaac cgatttaaat ggagaaatga agtttcgttt tcattgctgt
    25861 cagggggaaa tcggccatca ccatcatttt atctgtacag tgtgcggaac aacgaaagaa
    25921 atccatatgt gtccgatgaa ttatttcgaa gaacagctag gtggatgcac gatcgaaggg
    25981 catagattcg agattttcgg aagatgtgaa aattgtcaat aagggtttaa ataaaataac
    26041 atttgataat tttaaaaaaa agcaagattt ccttgacggt caaaacagca ttagatataa
    26101 tatttacagg acagtcttgt tttttgagat atatttcaat aacaattacg gttacttttt
    26161 aagctcggag ggagggaatt aacatgtcaa aaacagtcgt tcgcaaaaac gaatcacttg
    26221 acgatgctct tcgtcgcttc aaacgttccg tgtcaaaagc gggtacttta caagaatctc
    26281 gtaaacgtga attctacgaa aaaccaagtg taagacgcaa gaaaaaatct gaagcagcta
    26341 gaaaacgcaa aaaattctag ttctgtgatg aattggagtt ggtagtgtgt cactactaag
    26401 tagattaaac gatgacatga aagcagcgat gaaagcgaaa gataaggaat ctttacaagt
    26461 catccgaatg atcaagtcat ctatacaaaa cgagcagatt aaagaaggtc acgacttgac
    26521 agaagaagaa gaactaacgg tgttgtctcg cgaaatgaaa cagcgacgtg attctttgca
    26581 tgagtttgaa gaagcaggac gtgacgattt agctgaaaaa gtaaaaagtg aaattgtaat
    26641 agtcgaaaaa tatatgccgg aacaactttc cgatgaagaa attcgacaac ttgttcaaga
    26701 agcaatcact caaactggtg cttcatcaat gaaagaattt ggcaaagtta tgggtgcaat
    26761 tatgcctaaa gtcaaaggaa aagcagatgg aaaccaagtg aatgcgattg tgaaagaact
    26821 attacaatct taattttatc atttaaactg cggacagtga ttgtccgcag ttttttgtgt
    26881 tcgtaaaaaa agaa
//
LOCUS       DAFBSV010000033        26832 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.034, whole genome shotgun sequence.
ACCESSION   DAFBSV010000033 DAFBSV010000000
VERSION     DAFBSV010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26832
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.034"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(717..3866)
                     /locus_tag="LLB18_001294"
     CDS             complement(717..3866)
                     /locus_tag="LLB18_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HBK5244305.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYNTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(3880..5124)
                     /locus_tag="LLB18_001295"
     CDS             complement(3880..5124)
                     /locus_tag="LLB18_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBK5244306.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELIKFKLEPGDFIMSGAGTIGRIS
                     RVPKQIKPGVFNQALIRLRINKEITDSEYFIQFIRADFMQRKLTGANPGSAITNLVPM
                     SEVKKWIVQFPILEEQKKIGNFFKQLDDTIALQQRKLDLLKETKKGFLQKMFPKNGAK
                     VPEIRFPGFTEDWEQRKFKEFSKKTGKKNTKDLDFPAYSVSNKAGLISQTEQFDGSRL
                     DDLEKTNYKFVEPNEFAYNPARVNVGSIAFNNLGMTVIVSSLYVVVKMSEDLDNEFIL
                     QFIKSPTFIKEVKRNTEGSVREYLFYENFANIKFPFTRNKEEQQKIGAFFKQLDDTIA
                     LHQRKLDLLKETKKGFLQKMFV"
     gene            complement(5117..6709)
                     /locus_tag="LLB18_001296"
     CDS             complement(5117..6709)
                     /locus_tag="LLB18_001296"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HBK5244307.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
     gene            complement(7218..7943)
                     /locus_tag="LLB18_001297"
     CDS             complement(7218..7943)
                     /locus_tag="LLB18_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244308.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(8097..8423)
                     /locus_tag="LLB18_001298"
     CDS             complement(8097..8423)
                     /locus_tag="LLB18_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244309.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(8460..8825)
                     /locus_tag="LLB18_001299"
     CDS             complement(8460..8825)
                     /locus_tag="LLB18_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBK5244310.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(8862..9077)
                     /locus_tag="LLB18_001300"
     CDS             complement(8862..9077)
                     /locus_tag="LLB18_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5244311.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            9206..9541
                     /locus_tag="LLB18_001301"
     CDS             9206..9541
                     /locus_tag="LLB18_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5244312.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(9617..11614)
                     /locus_tag="LLB18_001302"
     CDS             complement(9617..11614)
                     /locus_tag="LLB18_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244313.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(11712..11987)
                     /locus_tag="LLB18_001303"
     CDS             complement(11712..11987)
                     /locus_tag="LLB18_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5244314.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            12219..12953
                     /locus_tag="LLB18_001304"
     CDS             12219..12953
                     /locus_tag="LLB18_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5244315.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            12992..14134
                     /locus_tag="LLB18_001305"
     CDS             12992..14134
                     /locus_tag="LLB18_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBK5244316.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(14229..15620)
                     /gene="sufB"
                     /locus_tag="LLB18_001306"
     CDS             complement(14229..15620)
                     /gene="sufB"
                     /locus_tag="LLB18_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HBK5244317.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(15625..16095)
                     /locus_tag="LLB18_001307"
     CDS             complement(15625..16095)
                     /locus_tag="LLB18_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HBK5244318.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(16082..17317)
                     /locus_tag="LLB18_001308"
     CDS             complement(16082..17317)
                     /locus_tag="LLB18_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBK5244319.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(17314..18600)
                     /gene="sufD"
                     /locus_tag="LLB18_001309"
     CDS             complement(17314..18600)
                     /gene="sufD"
                     /locus_tag="LLB18_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HBK5244320.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(18613..19386)
                     /gene="sufC"
                     /locus_tag="LLB18_001310"
     CDS             complement(18613..19386)
                     /gene="sufC"
                     /locus_tag="LLB18_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HBK5244321.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(19583..20431)
                     /locus_tag="LLB18_001311"
     CDS             complement(19583..20431)
                     /locus_tag="LLB18_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBK5244322.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(20455..21141)
                     /locus_tag="LLB18_001312"
     CDS             complement(20455..21141)
                     /locus_tag="LLB18_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5244323.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(21134..22168)
                     /locus_tag="LLB18_001313"
     CDS             complement(21134..22168)
                     /locus_tag="LLB18_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK5244324.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(22231..22487)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(22563..22901)
                     /locus_tag="LLB18_001314"
     CDS             complement(22563..22901)
                     /locus_tag="LLB18_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HBK5244325.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(22903..23259)
                     /locus_tag="LLB18_001315"
     CDS             complement(22903..23259)
                     /locus_tag="LLB18_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBK5244326.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(23265..24452)
                     /locus_tag="LLB18_001316"
     CDS             complement(23265..24452)
                     /locus_tag="LLB18_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBK5244327.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(24643..25488)
                     /locus_tag="LLB18_001317"
     CDS             complement(24643..25488)
                     /locus_tag="LLB18_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK5244328.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            25722..26687
                     /locus_tag="LLB18_001318"
     CDS             25722..26687
                     /locus_tag="LLB18_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBK5244329.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
BASE COUNT         7690 a         5548 c         4514 g         9080 t
ORIGIN      
        1 gactaataca ggtagtcctc ttttttgtta ttttgatatt ctaaatcatt ttttattgga
       61 ttattccctt gttcgatata gacccaaatt gatctatcaa taattatcaa actgagtcat
      121 atagagacaa aaatttcaaa aatgacctgt taaatggtca tcgaatatca tttaaaatca
      181 atacgacgga gtcagacacg gagtcaaaac aagcccgctg agagtaaaaa atatatacag
      241 tcccataggt aaagtgccac aggactgtat atttttttat ttgagattac ctgaaatgat
      301 tccatttact ttttatctca ttttttccta ctagttagta tcaaatactc tcctattttc
      361 tcaataaact attttgggtt acatggtatc tgaaacagct aaaaccttgt cattacagca
      421 aaaaatcact ttatctccgt ttcatttcag atacatttca cttaagcgga ttccaaaaaa
      481 acaaaagaaa aaggaacccc tagttagcct atgcttttta ttggttcctc tcaaaacacg
      541 gtcatataac aacggggtgg ggtaaatgaa tgaaaaaggt ggaggaaaca ttattcaata
      601 gctgtcttaa atacttcgtt ataaaatgtg aacaaataaa agacatctat ccctattttc
      661 tacacttcca ctttactacc atctttgaat cgtacaattt tcttaactct tctcgtttac
      721 ctcaattcat tttcaagtgg aatcagctca tcatctaaca ttttacgcca tgctcgcttc
      781 atttcttgtg ggtatttaaa tggcttcgct tctggatggt tggctttata tccttcgtaa
      841 tccttactgt tgataattgc tttcatatta ggaattggat cttcacctgg catatattgc
      901 agattagaag catgtaattc tttctcagaa acaaaccact cattggaaaa gacatgaatc
      961 aaatcatcac tcgcttgtgt aaaatagcga cgtttaatga caaagatatc ttcattacta
     1021 tctaaagtcc ccacatcaaa cgcatttaaa atttgtcggt aaacttcttt gactccttct
     1081 gttttattca atttagccaa agctttttca atttcttctc gtgcatctga actattcgcc
     1141 gcataagttc ctagtaattg atcaatataa gtagaatcaa tatcatacaa cttcgtggta
     1201 ttttcactat aaaattcgat cgtggaaaaa tcttctccct ctttttctgg ttcttcctct
     1261 attaatgaac ccttcacggt ctcgtacacg ccaatttgtt cttccaaaag ttgaatttga
     1321 ttgttcaagg ttgaagattt caccatgtca tcattgtaat cgtcataagt cactaacgat
     1381 tcataagcac gattcaattc ttggaatgct ttgacgtact cgatacggat ttcaagtggc
     1441 gtatgttcat caatggattc catggatgaa acctctttta acttaccata tgcttgcttg
     1501 aatctttttt tggattcctg ataacttgga taaatcaaac ccgattcttc ttttgcttct
     1561 gaatacagtt ttgtcgcatc ctcgacattc ttctccattg tggctggctt tcggaaagta
     1621 acaattagtc cttttgtttt ttctggatac gtacggttcg tacgtgaaaa agcttggatc
     1681 aatcctgcat actctagatt acgatccaca aatagggttt gaatcgtagg tgcgtcaaaa
     1741 cctgtcaata gacgatccac tacgatcact aaatcaattt gtttcccaaa ttgtttgaat
     1801 tccgctcttt ttcgtgccaa acgattattg atgtctccgt tataacgctc aatgtctgct
     1861 aatgaccagg aagtattata atactgatta tattcctcaa taattttttg catttcttct
     1921 tgttggacac ttgaatctcg gctgttttct tctaatgaat aggtaatagc gattcgtgga
     1981 aaatcaggat cctccatcgt tcttccttca cgaatgggct gattaggaaa ctcttttgtt
     2041 aaccagtcag gttctttcgt catttctttg atcgctcgat aatacttttt ggccatgtca
     2101 atggaactcg tggttaagat cgcagacttc gttggacggc catttcgaaa atcaaatttt
     2161 gtataggcat tgtctggacg gaacatttta tgaatgactt tttggatatg ttcatctgct
     2221 tcaaaaacag tagggtccaa ataactttct tttttgacag gctccatttg atcaatcata
     2281 cgattgatct gttccggtga atactctgca tatgtttcta cttcttttaa tttccgatag
     2341 attttattct ctaatgaagt cggctccacg gtgttttcat gctctacttg aaatcctaaa
     2401 accgagccat cttctaatgc attcttgatg gtataggtat gcaagacctc tccatactga
     2461 tcatgggtcg tacgtgccaa ttgccctttg gcttgtttcc gattctcagg gaaaatcggt
     2521 gtacctgtaa agccaaacca agtggatttc ggaaacattt ttttgatttc ttccatattt
     2581 tcagcactta acgctcgatg acactcatct actacaaaca cgatatgttg ccccattaat
     2641 ttttggaagc gattggttcc ttttttctct tcttgttttt ttgcatattt caacgccgca
     2701 tctagctttt gacgggttgt aataatcaca acatttgcat tggcatctgc caacagagtt
     2761 tcacttaact ctttggcact tcctgttccc acgatcaagc tattcgcttt ggcgttcccg
     2821 gaagaaatcc cagtattaaa ttccgaagca aatttcgtaa actctgtggt ggtttgatta
     2881 tctaaatctt tgcggtccac taacatgatc gtccgatcga tccccgattt tcgtgctaaa
     2941 agcttagtag atacaaaact agtcaacgtt tttcctgaac cagtcgcatg ccacacatat
     3001 cctgattgat gtttatttgc agcaataaac aaggcttgaa tcgcatgtac ttgataagga
     3061 tgtaacacca tgaggatttt attgtcttga tcttcactga caatcgtata atccgcaatc
     3121 aagcgatgag catccgggat atttagcact tgtttgcaaa actcatataa gttttctacc
     3181 tttttattat ctttcgttcg ccaactaaat aaaaacttag gatgcaaatc ctttggtaag
     3241 gcatttgcaa aataccgagt ggtttgttca ttggaaacca caaacaactg taaggtcgaa
     3301 aagatattgt tccgaaacat accttcttct gcatattttt tgatttggtt aaacgcctga
     3361 taaaaactat cttttgcggt tacttgtttc agctcgattt ggacaatcgg taatccattg
     3421 atcagtaagg tgacgtcaaa acgtcgatcc cgtgcttcta tgttacttcc acgttttgca
     3481 atttgatgga ccacttcata ggtagagatt cctccaccaa tgtcttgatt agaataaaga
     3541 atgagcgaga cagaacccag ttgcggatct tcccgttcaa tcgtgatccg agccattcca
     3601 ttttcacctt ttaaccattt cgcagcatca aagggggttt tcgttcgtag taacaattct
     3661 gttttgatcg tttcaaattc tttatcggtc aaaggaaaat cattcagttc tgcttgatta
     3721 tttgagatga ttttttggcg taaattgacc caaagatctt cttctgattt tagatcggga
     3781 cgatacgtcc actgattatg cccttccccc aatacacgga tcaactgttc ttcgacttcc
     3841 gcttcctcac ggtgactaat tttcatttat cttccctccc taaacaaaca tcttttgtaa
     3901 gaagcctttt ttcgtttcct tcagcaaatc taacttacgt tgatgaagag cgatcgtgtc
     3961 gtcgagttgt ttgaagaaag cgccgatttt ttgttgttcc tctttattcc tagtaaaagg
     4021 aaacttgata ttagcgaaat tctcatagaa taagtattct cgtacgcttc cttcagtgtt
     4081 gcgcttgacc tctttgataa atgttggtga cttgataaac tgaagtatga actcattatc
     4141 taagtcctcg ctcattttca caactacata aagagagcta acaatgaccg tcataccaag
     4201 attgttaaat gcaattgatc ctacgtttac tcttgctgga ttataggcga attcatttgg
     4261 ttcaacgaat ttataatttg ttttttctaa atcatccaac ctactaccat caaactgttc
     4321 tgtttgagaa attaaacctg ctttattact taccgaatag gcagggaagt ctaaatcttt
     4381 cgtgttcttt tttccagtct tcttactaaa ctctttgaac ttacgctgtt cccaatcttc
     4441 cgtaaatcca ggaaaccgaa tttctggcac ttttgctccg tttttaggga acattttttg
     4501 taagaatcct tttttcgttt cctttaataa atctagctta cgttgttgaa gagcgatagt
     4561 gtcgtccagt tgtttgaaga agttcccaat tttcttttgt tcttctaata ttggaaattg
     4621 tactatccat tttttcactt ctgacattgg tacgagattt gtaattgctg aacctggatt
     4681 agctcctgtg agttttcttt gcataaaatc tgcacgaata aattgaataa aatattctga
     4741 atctgtgatt tctttattta ttctaagtct aatcaaagcc tgattgaata cacccggttt
     4801 tatttgcttt ggtactcttg aaattctccc aattgttcca gcgccactca tgataaaatc
     4861 gcctggttct aatttaaatt tgattaattc attatatttt ttttcagtaa ttttatatct
     4921 tgtttcgtaa ttatcataaa tagcattttg ttgttcatag acaacaaaat tgctattaga
     4981 tacaaagaat tctttcttta aggcactccc aaatggtccc ctccttactc catctttttt
     5041 atcaagtaag cattcaaact tacgctgttc ccaagcttcc gtaaatcctg ggaaacgaat
     5101 ttctggttgt atatcattac tcatgtttga acacctccag cgcaccttgt aaccacgctt
     5161 cattttcagg tgttgtttgc agggaagaga tagcttctaa aagttctttt tctagcactt
     5221 gctgttcttg tcgtatcttc ttgatgtcat ttccgacatg aaccatatca attggttctt
     5281 cttcttcaaa cgtatctaca tagcgtggaa tatttaagtt atagtcattt tctttgattt
     5341 catcaaagtt tgccaaatga gcgtatttct cgacatcttt tctttcagca taggtttcga
     5401 ggattttttg aatgttttct tccgataatt tattctgatt ttttcctttg acaaattctc
     5461 gactagcgtc aatgaataat acgtctcgag tttggcggtt ctttttcaat acaatcaccg
     5521 tcgttggaat cgatgtcccg aagaacaagt tcgcaggcat accgatcaca gcataaatac
     5581 tgccgtcttc tagtaatttt tgacgaatga ccccttctgc agcgccacgg aataaaactc
     5641 cgtgtggcaa gacgatggcc atagtccctg tttccttcaa atgatagaaa ccatgaagaa
     5701 gaaacgcaaa atctgctttg gattttggcg ctaattttcc ataacgatta aaccgagaat
     5761 cgtctaagaa ggtcgtatct gctgaccaat tagccgaata aggtgggttc attactactg
     5821 catcaaatgt gtaaggttca tctgttggcc aatccttatt caacgtatcc ccattgcgga
     5881 gattcatttc ttcggcatct accccatgta aaatcaagtt catttttgct agattgtatg
     5941 tcgttgtatt taattcttgc ccatgatatt taacgttatc tgggtgagtt aagtagttac
     6001 gcacatttaa catcaatgaa cctgaaccca tggttggatc aaaaacacta aagaatcgtc
     6061 gttctttttg atccaacgtc acgatttgtg ccatcatatc agaaaccata tgaggcgtgt
     6121 aaaattctcc ggctttcttc cctgcttctg aagcaaattg actgatcaga aattcataag
     6181 catccccgat cacgtcccca tcgtgaccta aaacttccac gtcattcaat ttcttaatga
     6241 cttcggtaat cgtcacattt cgttgttgct catctgttcc tagttttttt gattggagat
     6301 ccacatcatc aaataaccca ttaaattgat tgtaggtaga tgccaattgc acaaaggctt
     6361 tgtttagatc attcaattgg aacgttgctt gttttgcttg atccgctaag acgttgaaaa
     6421 gatactctgg cgaaatcgca taccccaaaa tatcaacgat tgttgcaatc agatcttctt
     6481 ttgattcttc atctgaaagt aattcgcgat acaacatcgt ttgtttgctt accgtatcat
     6541 attcctctaa ggattcatct gctaaaagaa ccacttgttc caacaaacgg tcggataaat
     6601 atttatagaa aatcagtccc aataaataat ttttatattc tgacgcatcc attttgctac
     6661 ggagattatc tgccgcacta aataattttt gatttaattc tgcacccaaa aagatacact
     6721 cctatctctt atttaaagtt gctatatacc ctcttatttt agcatactcc cttttagaaa
     6781 aagcaaaaaa aaaagaaaga aacttattct tgctaataaa ctacgcgaaa ggagtctaac
     6841 gttgtttgat ataacttaga ctgatcgtta acttattttt tatatttcta catagttatc
     6901 tttagaacca tttcagatac atatgaaaca attacatatg attttttcat aaaaaaacag
     6961 tactgtctag tagtataaaa tatacaaatt tcttaaaaat tttttcacta aaatcactac
     7021 ctgaaacagt ctaaaacact tatatatcaa cgtttaatga aactatctcc gtttcatttc
     7081 agatacaaat aaatatagtc gggctccaaa tccgaaaaaa aataccccca gtagcttatc
     7141 ctaagctact ggagatgtat aagtacggtc atataacaac ggggtagggt aaataaatga
     7201 aaaagatgga agaatcatta ttcaataact tttttaaata cttcgttgta atcagttacc
     7261 tgtccgttct taaataccac agaataatct tttttcccat tttcaagtaa ccgaagtgga
     7321 atatctttac caactttctc tgtcactgca ttactgatac ctgttagatt agctaataaa
     7381 tctgataaag attgagcatc tgtagaaatc tctgtatcag tatttatcgt gattccttta
     7441 tcttcattta caagtttcca agtaggtggt atagctgtgt atgtttctac aaatgaatta
     7501 agtttttcat taagtgactt ctcttttata tttccatcta aaaactctgt atatatggct
     7561 tgagctatac taaaacaaag ctggccttgt tctaataatt ttacatcatt agttagtaaa
     7621 gctgtgttca cgttatcaat cgcttcaaga agagtatctt tggtgtccct aacagcttta
     7681 ggtgtgcctt ctggaatttc cctacttgat acctcgtcca ttttatcttc cataaacccc
     7741 ttaaaatcat atctttctcc caaatccata gaagtttttg agaaagcttt catttctgag
     7801 tctatttctt caataatatt taacatgtct gatacatatt gtttaggctg attcgttttt
     7861 aatctatatg tggtaaatat ctcaattcct ccaattatca ataaaattgc caaacaaatc
     7921 cataataatt ttttcttttt catttttcct cctatacact gctgttataa cagtgactaa
     7981 tgtaaagatt ttcccagcaa tcatcagact attatttaca gggaatcaaa aaaactcctt
     8041 agtaagctta cacctttagg agttcctgtt tgaacggtat gcataataca tttaaatcaa
     8101 tttaacatta acacctcagt atatggtatc tctacatata cacggtcttt ttttggatag
     8161 tactcgacat ttatattgat agcacttcca ttgtctaacg tagctttagc ccggtacgtg
     8221 ttatcaccat tatcatgagt gatcgtcaca tcatcacatg tccgatttaa gttatactgt
     8281 tcttgtaaaa tctgagttac caatggtaca gatgacttct ctagtccaga tgaacccgtc
     8341 attcttgaaa aaattatacc tataatagcc aatacaacga tacctataat gacaaacttc
     8401 ttattcatat ttactttatt caacttttta tctcctatct ccaaaatgat tttctctcat
     8461 cagtaactca ttgacatccc caatagtaca ccaaagatgg ctccagctac ccctgctatc
     8521 atcaaaatcg tacccatttg ttcatctttc tctcgatata agtaacccat aataacagca
     8581 acagcaccaa ataccacagg aataaatgct aatgatacta ccatagaaat ccaaccaata
     8641 atcaaataca gcttccctgt ctcttgtcca tgtacgattt gttccttcat ttcattaatt
     8701 gtctgctcag tacttttctt tactgtgtct gttccggttg tctcatctgt ttcttgtaat
     8761 gctccgcaaa actggcaata cttactttca tttgttattt ctttaccaca ttttctacaa
     8821 tacatgtctt ctcctcctaa aatcattcaa ttgcttatta gctaactgtt tactttatta
     8881 aatacatcag aaaacagctc atttattggt acacttaata tctcagaaag cattttcatt
     8941 tgatagggtt taggaatcgt tctccctgtt tgccacgaac ttacacattg ctgtgtaaca
     9001 ttcatttttt tggctaactc agtttgggaa agtccttttt cttttctgta tcggctgaga
     9061 ttacttactt ttttcatgat tctcccctcc tgttttatta tatacaacaa tatgatgtat
     9121 ttcaactcat aaaatatata aatacttcaa atgtcattac aaatacaaca acttgttgta
     9181 ctctactgag aaggggggtg tattaatgaa acagaagcaa tatgcaaagg tcattagaga
     9241 aaagcgaaaa gcactcgggt ggacacaaaa agaattagct aaaaaaatct tctctacaca
     9301 acaggcagta gcaagatggg aaaattctgt aacagaacct aacctcgata gcttaacagc
     9361 tctttctaga gccctaggaa cccctgtaag ccattttcta gacaatgttg acatagatta
     9421 tgaggaagag tttttggctc tctatcgctc tcttagtact gaagatgcaa ttcgaacaat
     9481 tgactatatg aagctattaa aaaggcaaga aaatgaacgc aatcagctat tgaaagattg
     9541 aaaaataaat aacccaccga actttaacgg tgggtgtatt gagatgaaat aagattaaga
     9601 gctatggata acctgtctag tttaatataa ttgggtctct tctattcctt actctccgtc
     9661 catcatctct tgttacactt gtaaattgat aaataggaac taattcaact cctgataata
     9721 tcaattcttt tattacttca tctatccctg cccctttcgc tagatatact aaaaaactac
     9781 tgcttgcttt cacattgtat agtttcttaa tatccttaga agctcgttca agagtgaatc
     9841 cttgtttaac aaagtagcct ctgttttcta ttaaagcatt tttcacgctg ttatccctga
     9901 catttcgtag gcgttcacaa acagtgttaa taagttcttt ttctgtcatt agatatgtcc
     9961 cttgccacga taagccctgt aaaacttcat gtgcttcatc taaaatcaat tgtttttcct
    10021 tgctaagttc tgatcgggaa ttttgaggaa atactctttt agcctctttt tcgttaaaac
    10081 atatcttaac ccattcataa gaaaaatatt gatatgtaaa atgaaatttt tccagaagtg
    10141 gaaggatatc ttcattcaat ttttgaatca cagaagttgc attaaaaacg tctaatcgat
    10201 agacattgct tctcttatgt ttaaagtttc ctaacgcttt ctcttccttt aacctattta
    10261 ggtattcgag catcttcaaa ggaacatctt catcatctaa tttttttatc aatcctataa
    10321 aagtcataag tgatagtaac ttattacatt tatctatgtc ataagtttta ccatagtaag
    10381 aactcatttt tttagctaat tgttcccccg acaaaataca agtcacactt tccttactat
    10441 catcaaaaaa attaacatca gaaagcaaga catcatagac acgtcgcatt tcctctagat
    10501 aattccttat tgtcctgaaa agtttgtctt tcattgattc aagagtgtca aaaagtactt
    10561 ttgattcctc tttcaatttt cgaaaatgtg taggatacaa gtctaggttc tctaatagcc
    10621 aattaaatgt ttctacccga ctgtctttct ttaaaattag catcacaact ccaataaaat
    10681 tttcactgat atcacaatta ctggaatgac aataaaaaat ggaatgccca gttttactgg
    10741 taaaaatact agcagaggga ttatgatcgt tgtgaaacag acatcttaag tttttacttg
    10801 acttaagtaa tttattcata tcaatggtta acaatctttc ataaatctca ttaaaagaca
    10861 tgtcggagga atcaaacagg cagtctttaa accactgttt catttcttct ttgtcgtcat
    10921 tttttatcaa cttaacaaaa tcggtttcat tgactagttc atactctctc cctgaatcac
    10981 tttgacaatt tttagaacat gtcatggtaa aatcaatcgg aagctcagta atatctaaca
    11041 tgttgtcttc attaattatt atcactgcat ctgacttata tcctccaaaa aacattctat
    11101 tcgaagcatt tacattgtca tcacacccgg ggatgttctt tttcaagtat tcgtaaacag
    11161 caaccatttt accatagtca gtaattgctt cttttaatag aaagacaatc ttgtattttt
    11221 ctagattttc agagtaccga atactttttt gtatcgcaaa cgcagaatta tgaactaaat
    11281 tgatagataa aaccttttct atgcttaagt atctactatc atctttactc aaatctacta
    11341 ccttcccctt ctcatcttta acagtgttat cgacatccag aataattact ctggtttcca
    11401 caaaactctc cttgtcattg cctttattct ttgtcttgct tggaataaat gattgtgatg
    11461 aatttagtat ctctacaaac tcatctcttg taacttctct atagttatct aaacacctat
    11521 ctcttacatc agttttttct ttttttgtaa ctggcttctc taataatttt tcttgatcta
    11581 cataaattgg aatattaatc attgatgttt ccatttgtgt ttcctcctta taaaattctg
    11641 ttaaagacta aaacatacag ataataaaaa caaactcttt attactatat gttttagtct
    11701 tatttgttta ctcaaccttt ataccgttcc atgaaactat caatatcaga ttttttaaat
    11761 ctaatgaccg tatcaatttt tataacaggt aacccgtatt gagaaacata ttttctaatc
    11821 gttcctactg atacacctag atattcactt gcctgctgat agtccatata ctctagagtg
    11881 actccagaaa taatgtcttc tagcataggc tttagcactg taattatctc tttcacttgt
    11941 tgttcaactt gtatagaaac aatgctatca atgatttgta gagacatatt tccccctcct
    12001 ttcgtgattg cttgaacaaa ttttctaaga attatcttcg tattttttgc tcaaaataaa
    12061 agtattttgt tattaaccga ttaatcaaac aaaaaatgat taccagttca tcgacataca
    12121 cataatacct cgataaaaaa ggggtgtcaa cagctttgta aaatttattt acaacacccc
    12181 ttttttgagg tatactaatt ttaggaggtg tggtcaatat gataaaacgt ccaccaataa
    12241 attatttaga acgaaaaaag atactcggaa caaaaataaa agctataaga aagagtaaaa
    12301 aattaacaca accagcattt ggtcttatga ttaacaacgg tcaattaatt gacaaaaaaa
    12361 ctatctacga atgggagaag ggaacctatt taccaatacc agagcgatta tcccgaattg
    12421 ctgatttggg aaatatgagt atagaggagt tagtttgtgg caatgtagaa gaatatattt
    12481 tgggaattat tctttataga gatagcattg tactagatgg tataacattt ccagataaaa
    12541 acctgttcca gcatcttcgt caacagttcc caccagtaca ctctaattta gatacatggc
    12601 tggatagata ttccaaatta gaaccagaga tgcaagaatt tattgctaac aagacttgta
    12661 ataaagttaa aaatgaaaaa attagtcttt tcaatatctt aaaaatagaa gaattattca
    12721 tcaatgctat tgtagaagaa tttgacaata acattctttt cctcactagc agtatagaag
    12781 aactactaga aagaatggta gatgaatggc tacctattca attgaaagac atgtcttatc
    12841 ccgaagaagc tgtgagagaa attactgata atataaacaa gctagaacaa acgatttcat
    12901 caattgggaa aaaatacact aagaaaaaaa tgaagggagg tgataccatc tagtggtaag
    12961 tactccttgt aaactaagag gagatgattt aatggcaaaa atatcaaagt acaaaaagaa
    13021 aaacggtcaa gtggcgtgga tgtataaagg acacattgcc accgatccac gaactggtga
    13081 aaaaataaat actacgagaa gaggttttag tagcaaacaa gaagctcaaa aagattatga
    13141 cgagtacaga catcaaatat tatacggtgt taaaaagaaa gcacctgata tgacatttga
    13201 agacctgtat aatgaatgga taactcatca gcgtaccagt gttaaagctt caacaatcgc
    13261 aatctcagta agatacgcaa ataatcaaat acttccagca tttggtaagc ttaaactatc
    13321 gaatatctct gtcccatatt gtcaaaaagt ggtagatgaa tggcacagta aatatgaaag
    13381 ttacgattat atgagaaaac agactgcaca aattttacgc tacggggttg caatgcaata
    13441 tattgacaat aatcctatgg aaaaaacact tcttccacga aaaaaagagt atgagaaaaa
    13501 tcgtaaattt tactcaaaag aggagcttaa taatttactg gatgctttta aagattttgg
    13561 taacatgaaa caatacgcct tcttcagatt attggcatac acaggtatga gaaagagtga
    13621 agtactcgct ttacagtgga aagacataga cacgtttaat aaagaactac atgtcaataa
    13681 aactcttgct gtagatgaat ttggtaaagt tataattcaa tctccgaaaa caagagcttc
    13741 tagacgagtt atctctttag atactgagac tctttctatc ctcaacaact ggaaattaca
    13801 gcaaaaagaa gagtatttaa aacttggata caatactagc tctaaagagc aacatgtttt
    13861 tacaacagtt aaaaacactc tatacattcc aaacactgtt aatgattggt taagatatat
    13921 tttgaaaaaa tataacttgc ctcgtattac acctcatggg tttagacata cacatgctag
    13981 tttattatta gaagcaggag aatctgtcaa ggtagttcaa caacgattag ggcatgaaaa
    14041 tagtaaagtg acattagaca tctatgcaca tattacaaat aatgcaccta agaaaacagg
    14101 tcaagacttt gctgatatga tggctcatca gtaaaagagc tggtcaaaat ctggtcattt
    14161 ctagtataca ggcaaaacaa aaaagctaga acccttatat atcaagggtt ctagctccta
    14221 taacaggttt acccaacact gccttccatc tcataactga tcaatcgatt gagttcgact
    14281 gcatattcca ttggaagttc tttggtgaat ggttcaacaa agcccatgac gatcatttca
    14341 gttgcttcag attcggtcag gcctcggctc atcagatagt agagttgttc ttctgagatt
    14401 tttgagactt tggcttcgtg ttctaaagag acttggctgt tgtggatctc attgaatggg
    14461 atcgtatcgg atttcgacca ttcgtccatg atgatcgtgt cacattcgat atgagagatc
    14521 gaacccgcac tgtttttggc aaaggttact tgtcctcgat agtttacttc tccgccgtct
    14581 tttgaaattg atttagagac gatagagcta gatgtatttg gtgcattgtg gatcattttt
    14641 gcacccgtat cttggatttg gtttgctcct gcaaaggcga tggagagcat ggtgcctcgt
    14701 gcaccttttc catctaagta aacacttggg tatttcatcg ttgtttttgc acctaggttt
    14761 ccgtcgatcc attcaacggt tgcgccttcg tatgcttttg ctcgtttggt tactaagttg
    14821 tacacattgt ctgaccagtt ttggatcgtt gtgtaacggc aatacgcatc ttttcttgta
    14881 aagatttcta cgatggcggc atgcaggctg ttacttgaat aagtaggtgc cgtacaacct
    14941 tcgacatagt ggatgcttgc tccttcgtca acaatgatca gcgtacgttc gaattgcccc
    15001 gtgttttccg cattgatccg gaagtacgtt tgtaatggaa catcgacttt gacgcctttt
    15061 ggcacgtaaa taaaggtccc acctgaccat acggctgaat tcagcgctgc taatttgttg
    15121 tcggttggcg gtacaagttt tgaaaagtac tctttgaata attcagggta ttctttcaaa
    15181 gcagagtcag tgtcagtaaa gacgattcct aacttttcga attcatcttt catattatgg
    15241 tacacgactt ctgattcata ttgtgcggaa gcaccggcta gataagctcg ttcagcttct
    15301 ggtataccaa tcttttcaaa tgtatctttg attttttctg gtacgtcttc ccagtcacga
    15361 gcgggtttgt cacttggttt ttggtaatat ttgatggcat cgaaatcgat gtctgaaagg
    15421 tcggggcccc atgtttgcat tggcattttg ttaaatgttt ctagagattt cagacggaat
    15481 tcaagcatcc attctggttc gcctttgatt cttgacatct cacggatcac ttcttctgtc
    15541 aagccttctc ctgtactgaa aaccggttcg acatcatcgt gaaacccgaa tttatattct
    15601 tctaattctg gtacgcccat gttctcactc ctcttccttg tggtaatgat ggaaagctgc
    15661 ggtaccatcg ttttccattg cttttcctag tgctttccag gcaagtgtcg cacatttgat
    15721 ccgagcggga aatttagcta caccaccaag catagcagca tcgcctaatt ggtcgggatc
    15781 tttgacttct tttccttgga caagctgtag aaagtctaca gttaaatgtt ctgcttcttc
    15841 tattgatttt ccgatgacgg cgtctgtcat catcgaggca cttgccgtac tgatggagca
    15901 gccactgccg tcaaaggcga tatttttgat gattccgtct tttacatcga cttgcaattc
    15961 gatcacatct ccacatgtgg ggttgttcaa ttcgatcttg cttgtcgagt cagtcaagct
    16021 tccacgatga tgcggatggg aagaatgatc caagatcact tgacggtata aattgtctaa
    16081 tttagatagt cccatgttgg aaaaactcct ttgttgccat gattgcttca actaaacggt
    16141 cggcgtcttg cgttgtgttg tagaaataaa agctcgcgcg agcagtcgct gatacttcaa
    16201 ggtacttcaa tagcggttgc gcacaatgat gacctgctct gacggctacc ccttccatgt
    16261 ctaaagctgt cgcgacatca tggggatgta acccatccaa attgaatgca acgactcctg
    16321 tccgaaaatt cgggtcttgt ggaccataaa cagtcaatcc atcaattgct tgtaattttg
    16381 gcaacacata agcggctagt tcttcttcat atcgatggat attgtccata ccgagttttt
    16441 gcaaataatc gattgcatgg cctaatgcga tagcgccggc gatatttggt gtccctgctt
    16501 cgaatttcca aggtagttct ttccatgtac tgtcgtataa ttcgacaaaa tcgatcattt
    16561 cgccaccaaa ttcaacaggt tccatttctt ctaaccattt tcgtttacca tataaaacac
    16621 caatacctgt tggtccgcac attttgtgtc cgctgaaagc aaagaaatca cagtctagtg
    16681 cttggacatc aatggccatg tgcggggcag attgagcacc atctactacg atgaccccgc
    16741 cgttttcatg gacaagttca gctaattctt gaacaggatt gaagacacct aagacattgg
    16801 atacatgagc aatggagacg attttggttt tgtccgtaat ctttttcgct gcatcctcca
    16861 tatccaggaa gccttcttct gttagttcga tatatttcaa gacagcacct gttcgttttg
    16921 ccaactgctg ccacgggata acattagaat gatgttccat gtaagagagc actatctcgt
    16981 ctcctgcttt gatatagcgg tcgccgaagg ttctggctac ccaattcaag cttgtcgtcg
    17041 taccacgagt aaacagcact tctgctgttt cttttgcatg gatgaacgcc cgtacttttt
    17101 ctcttgcttg ttcataatca tgggtcgcgc gttctgctaa cgtatggaca ccgcgatgaa
    17161 cattggcgtt atcgtgttcg taatagtacg ctaatgcctg gagtacttgt tttggctttt
    17221 gggtcgtcgc tgcattatcc agataaacta aaggttcatc attgacgtct tgaaataaga
    17281 taggaaaatc attgcgtagc tttttagcat cgatcatcca ttcaacttcc cttcgattac
    17341 ttcgactaat tctttccgaa cttgttctac agggattgct gttaagacag aaccgaggaa
    17401 tcctcgaatc actaagcgct ctgcttcttc tttatgcaat cctctactca tcagatagta
    17461 catttcttct ggatcaactc gtcctacact ggcagcatgt ccagcagtta cttcgttttc
    17521 atcgatcaaa agaataggat tcgcatcacc acgtgcttta tcagaaagca tcaagacacg
    17581 actttcttgt tgggcatctg caccttttgc ccctttcaag atgtggccga taccattaaa
    17641 ggtcaatgtt cctttttctc ggatcactcc gtgttgcaaa atatgcccga tcgtatgagg
    17701 ggctttattg gttactcgtg tatcgattcc ttggatttgt ctgcccgagc tgattgccac
    17761 gattttgact tctgcgtgtg caccttctcc tgctaaatct gagtcaaagt cagcgatcac
    17821 atgaccgtca ttcatgacac caattgccca gtcgacagaa gcatctcgta aaatgtgccc
    17881 acggcgattc atataagaag taatattttc tcctaattga tctacggctg aatatttgat
    17941 ttttgaacca gctttagcga tgacttccac gatgatatta cctgatgatt ttgctacttg
    18001 ttctttggtt gtctggaaac gttccagata agaaaattca ctatgttcat ctgccacgat
    18061 caacacatgc ttgaagaagt gctcatcgga tgcgccatct tgaatgaata aggactcgag
    18121 tggttcatcg atcacgacat ttttaggcac atacaggaaa ataccgctgt tcataaaagc
    18181 tacatggagt gcagtcaatt ggtcttcgtt catgtttact gcttttttca tataatattc
    18241 ttggactagt tctggatatt cgatcattgc agtgaacaag tcggtaaaaa tgactccttt
    18301 ttctgctaat tccacaggca gttgttcaaa aatcgtccat gaaccttgtt ggacaagcac
    18361 aggattgtct ttcattgcat caaatgccgg aatcgtgcct gtttcactga tggtttgtgt
    18421 ttctttcaca tcaaataacg accagcgatg gaatttcacc cgatcgatat gcggcaatgg
    18481 cagttcatct gctttcgcta gtgcgtcttg acggaaggtt ctcatccaat caggttcgcc
    18541 tttacttaaa gaaaaatcat ttaccgcgtc aagataatcg agccagtttt tttctttcat
    18601 tcttgctccc ccttacgctt cttcttcttt atagtcgatt cctaattctt tactgatacc
    18661 agcgtagcct tctgcttcca gacgtttagc taggtcagca ttccctgtca tgactactcg
    18721 gccttccatc atgatgtgaa cgacatcagg tgtgatatag ttcaataatc gttgatagtg
    18781 ggtgatgatc aatgcaccga aattgtctcc gcgcatttca tttactcctt tagcaacgac
    18841 tttcaaagca tcgatatcca gacctgaatc gatttcgtct aaaattgcaa atgtaggttc
    18901 taacatcaac aattgcagga tctcattccg tttcttttct ccgccagaaa aaccttcgtt
    18961 cagataacgt tcagccattt cttctggcat atttagtaaa gccatttttt catctaactt
    19021 tttcaaaaat gccataacag aaattttgtc gttttcatca cgtttcgcat tgatcgctgc
    19081 acgcatgaat tccgcattcg tgatacctgg tatctcactt ggatattgca tagctaaaaa
    19141 taagccaagt cgcgcacgtt catctacttc caagtctaaa acatttttcc cgtcaaacaa
    19201 aatttcgcct tctgttactt catagtttgg attgcccatg atagcggcag ataaggtaga
    19261 ttttcctgtg ccgttaggtc ccatgatggc atggatttct ccggttttca ttgttaggtt
    19321 tacgccttta aggatttctt tttcctcgat cgacacatgt agatttttta tttctaagac
    19381 agacatgcat tataccccca aattctcttt cgttctcact cattttagac taattgagaa
    19441 tgaagcgcaa tgaccttcct tactaaaatc aaatatcttt tatttattat taaacaattt
    19501 tgatttctaa attagaatag gtataaaaaa gatgagaaat aagccattac agacttattt
    19561 ctcatctttt ttgttccata ccttattttg catcagcctt tactggttta acagagccgc
    19621 cccatttgtc tgtgatccat tcttggactt ctttgcggtg aagcacttca atcagttttt
    19681 tgattttgtc actgtcttca tcacctttac gagtcgcaat aatattcacg taaggagagt
    19741 tgtccttttc aagcaatacg gcatcttcta atggattcaa ccctgcgccg taagcgaagt
    19801 ttgcgttgat tgcaactagg tcaccttcat cattttggta cgtagaagct aaaagtgatg
    19861 ggtcgatcgt atggttgaac ttcaagttct tagggttttc ttcaatatca tcgaatgttg
    19921 ctgtttccag atctactcca tctttgactt tgactaagcc agcatcttgt agaattgtga
    19981 tgatgcgtcc ccagtctgat tcagaatttg aagtaatgat tgttgcacca tcttttaatt
    20041 cggaaacatc tttgactttt ttagagtaca agcccattgg ttcgatgtgg acagcaccgg
    20101 cattgacaaa gtcatatcct ttttctttga tttctttgtt caaataagga atatgctgga
    20161 agtaattggc atcaatgtcg ccttcttcca aagattggtt cggtaataca tagtcatcga
    20221 atttgacgat ttcaagatcg attccttcat ctttcaataa tggtttcaca tgttccaaaa
    20281 tctctgcgtg cggtgtcggt gaagcgccga ctttcaatgt cgtgtcgtct gctttatttg
    20341 ctgaatcttt gctgtcgctg ttgttaccgc atgctgctaa tcctacagtc agcaaaagcg
    20401 ctgctgcaaa tccaaaaatt ttctttttca tatcctacat ccccctatat cctattatct
    20461 tttgtctgtt ttcttagtta agaaatcacc gattccttga acgataaata cgattagtaa
    20521 aataattaaa gtcgcaacga atgtcactgt tagattacca cgctggtagc cttcctgcca
    20581 agcaagacct ccaagtccac ctgcgccgat cgcgccggcc atcgcagtaa atccgatcat
    20641 cgagatcgtt gtaactgtta atccagaaat caatgcggga atactttcag gtatcaagac
    20701 cttccagatg atttcccagt aacttgctcc cattgcatct gctgcttcca gtacaccagg
    20761 gctgacttca cgaaaagcaa tctctactag acgggcataa aatggtgctg cggataaaac
    20821 aagagctgga atggctgctt gcgcacctag catagtgcct acgattgctt tagtaaatgg
    20881 aatgatcaaa accatcagga tcataaatgg cgttgaccgg aaaatattac tgatgatcga
    20941 tacgattcca taaatgattc gagcatacgg tttgtttttg cgtccaatag agtaaaggat
    21001 caatcccaaa actaatccga tgatcgtcac taagaccatt gagattaatg tcatatatag
    21061 tgtatcaagg atagcctgat tcatcgtttc cgggttgatt tgtttaaaat ctagatatgt
    21121 ttctgaaaag cttttatcca cgatggatca cctcaattcc tactccttgt tctttgatga
    21181 acacttctgc ttgatctaat tctttggttt caccagtcat caagacagtc aatgaaccaa
    21241 aggaaccttc tttcacttgt ttgatctttc catacacaac gttgacatcg atgttatagc
    21301 gtcgaatcgc ttgggaaatg actggctcgt tggcatttct ttcgctaaag gtcaaagttg
    21361 ccaaacggcc gcttggattt tctttgatga gttcagctaa tagttctgtc gaatcagctt
    21421 ctggttcgat gtcttgttgt acaaagcgtt tggttacttc ttttttcggt tgtctgaaga
    21481 cagtcaatac gtctccttct tctacgactt tccccaactc catcacagcg actttgttgc
    21541 agattttgcg gatcacattc atttcatgtg tgatcaagac gatggtcaaa ttcaatttct
    21601 tattgatcgc taacaataag tctaatactt cttctgttgt ttgcgggtcc aatgcgctag
    21661 tagcctcatc acaaagcagg atctcaggat catttgccaa tgctcgtgcg ataccgacgc
    21721 gttgtttctg tccgccggaa agttgtgaag gatatgcttg tccgcgtcct tctaacccga
    21781 ctaaacgcaa cagttcttct gcccgttctt tacgtttgct ctttggtacg ccagctaatt
    21841 ccagcggcag ctggatattt tcaagtacag ttcttgacca taacaggttg aaatgctgga
    21901 agatcatacc gattttcttt cggaatgtac gtaattcttt gttttttaat tttgtaatat
    21961 cttgatcgtt tacgatcact tcgccgctcg tgggaagctc aagtccattc aggagacgga
    22021 ctaatgtact ttttcctgcg ccagaatagc cgacgattcc ataaatatcc cctttttcaa
    22081 cgtttagtga aacgtcattg acggcttgga tgtttccgtt tttcccattg aatgtctttt
    22141 tgacattcgt tagttggatt aatgacatgc cattcacatc tttctcttat gatttttcaa
    22201 acaaaaaagc cttcgccctc ttgccttaag caaaaggacg aaagcttgaa cttccgtgtt
    22261 accaccttga tttaccgtta cttcgcaata acagcctctt ccagtacttg gacttagctt
    22321 ctttccgtat actgtcgcgc tgtaacgggc actcccgtag taagtttgct tacgctcgct
    22381 tactctgctc taagaccatc ttcaatctca ttttcgttac ccattttcag caaacagggc
    22441 tctcttcaaa cgtccgtgac atgtactctt cttttcaaag ctttctcgtt tcatatagga
    22501 ttgcttatga ttatagcaac tggaagaatc agtgtcaact tttttcaagt gattttctga
    22561 ttttataatt cgtcaaattc ttttggatca acatctttga aacttaagat ccacgcattc
    22621 atttcatctg aatcattcaa gatattgata tcttcaccga ttttatcatt aacagaagaa
    22681 actgtacccg ttagcgggct ggcaaattca ttgaccgctt tttccgcttc aacttcgatc
    22741 agaggttcat ctttttttag cgattgtcct gcttttggca gattggcaaa cgtgatgtct
    22801 ccaagttctt cttgcgcttc atttgtcaaa ccaacacagt attcttttcc attaaataag
    22861 atccaaaggt tgtccttttt cttcaaatgc ttgcctgcca ttttatatca gttctccttc
    22921 ataaattttt tcattgaatc caattgcaac aagctggtcc tctcgtaaga tcagtggtcg
    22981 cttgatcagc ataccatctg tcgataagac ttggctcgct tttgaagccg taaactcgcc
    23041 tacttgatct ttcagtccaa gttcccgata tttcatcccg cttgtgttga acaggcgacg
    23101 gattggtact tgactcgttt ctagccaagt ctcaatcgtt gaggccttcg gtacttcttt
    23161 gatcatatca acggtttgat aactaacgcc atgctggtct aaccacgctt tggctttttt
    23221 gcatgttgaa catttcgggt accagtaaaa ggtgtacaat tttcttacct ccttgaagat
    23281 cttgcaggtg cttcattttg gtatctcatc gataatatca acccgatacc gatcatgttc
    23341 cctaaaatcg aggatcctcc ctgactaatg aaaggcaatg ggatccctgt taaaggaagt
    23401 aatccgatat ttgctccaat attctcaaag acatggaaca gcagcatcat gatcaaaccg
    23461 cttgcgatat aggcgtaaaa ttcattattc gtatcgaaac acacccgaat catacgatag
    23521 attaaaataa aatacaagaa aatgacgaat gcaccaccga taaagccgaa gttttcaccg
    23581 ataacggtaa aaatcatatc ggactcacga acaggcacat agatattgct tacgttgaat
    23641 cctttaccaa acaagccacc ggtaccaatt gccaaaagtc cttgggccgg ctgataactc
    23701 attcctgacg tatcatggaa agggtccagc catgaatcaa tacgtgcaaa ctgataagat
    23761 ttgaatccaa ctttataaag caagtctctt ccgccttcag tcgtaaccaa gaagatcgtt
    23821 cctgctccaa cgactactgc caagattact acaggtgcga tgatgcgcca agagattcca
    23881 gacatcagga aaatcccgcc aaagatcgca agaaagacaa gcatcgttcc aaagtcatct
    23941 tgggccatga tcaatgctaa aaccggtatt gtcacgatca agagcttccc aatcagccaa
    24001 aagtccgatt tcatcgtccg ttcttttact tgcgtattat gtttagttac gatcagtgcc
    24061 atcatcaaga tgtacgcaat cttcatcaac tctgctggct ggaaagtaaa cgcaccgaat
    24121 cgaaaccagt ttttagaccc tgttgaagca gctaaattct gatcatagaa tttgagcaag
    24181 agtcccatta ccactaaccc caaaccataa aggtaaggag tcagtttcca gatccatttg
    24241 gaattcaaat gcatgatgac aacgattgct gccgctccaa ctaaatacca gacaacttgc
    24301 atccctacgc ctttcaagac tgctggattg ttcggatcat ggctaagtgc tacatataat
    24361 gagagcagac caatcaaaca taacagaaag actggtaaaa tcacgccata atcaatacga
    24421 ttatcgttcg aagcttttaa ttttttttcc atgtttcatc ccttttctta aaaaccatac
    24481 tgctgattat tatagcggtc cagttagata atggaaagtc tttccataga catttgggaa
    24541 aaattaactt tccgtttgtg cagttgcttg agcaaatgca gtacaaaagc ctactgctta
    24601 tctttagtgt atcatagaac tttttttgat acatgcaatt atctaccagc tgagattctc
    24661 ctcgctgtga gaagtttctg tgctttcatt gtatcgaagg atctcttcgg caatctctag
    24721 cagctgatca gaaaccagat tggttcgttg gatgaaataa aaatatcgat ggaaattcaa
    24781 cggagtcatt ggcacatttt ctggaacaga gcgcttagac aaaatcgagc gaccgattcc
    24841 ttccttcagc aacgcaacaa ttacatcgtt acttttcacg atcatcttct tatcttggat
    24901 attcatctct tcaaaataac gctgcgtgta atgaaaaaca ccagagtttg cttctcttac
    24961 aagccacaat ttgctttttg ggtccccagc gatgactagc tggtcttcca tcaaagagta
    25021 tctttgtacg ccggaagtct ctaatggctt ttcgataaaa ccaaaatcgg attcatgttt
    25081 cgctacttgt tctaatgatt catgagaatt cgtgatttcg atctcaaaat gcactttagg
    25141 aaaccttttg atcagatgtt tcatcaactg aggcaaaaga tagacagcaa aggtgtggga
    25201 agcaacgatc cgacatactt cttcttcatt ttgttcattg agcaattttt gctgagtttc
    25261 ttcccattct tctaacaaaa ccagtgtccg ttcatataat aagtcggctt gcttagttgg
    25321 aagcatctct tttcttccgt tacgttgaaa aagatcgata ttcaattccc gctccaactg
    25381 tttgatttga ttcgagactg ctggttgaga taaaaacagt acttctgctg ctctggaaaa
    25441 atttcttgtt tcatatactg ctcgaaaagt cgttaataac ttaaacatgg caccacttcc
    25501 ataacttttt atgataatta ctataaaaac tatttgattt aaatatacaa aaaaccatct
    25561 ataatagaaa tgtacaacaa aacagttgct gatccaacta gtaacttaga tgaagacaat
    25621 cagctgtctg cttgctcgta atcatacatt cctattcatt ttacaatgta ttcgttcatc
    25681 ttggtactaa aatctattaa ataaaaagga gaatattata tatgaagaac tttttgaaaa
    25741 ttattccgat cccgatctgc gggttgatcc ttgggttagc ttcccttgga aatctgttta
    25801 aagactatca ccatgttgct ttaggcaatc taactggcgg tatctctatg attcttatga
    25861 tattcatttt tgttaaattg tttatcttat tcgaacacac gaaacaaacg ttgcatgatc
    25921 caatcatcgc ctccgtttca ccaactttta cgatgtcact catggttatt tgtacttatt
    25981 ttgtttcata tgaaagtatt gcaccaattg tcaaattcat ttggctgtgc gctgttatct
    26041 tccaagtgat ccttgtcttt tatttcaatt atcaccatgt tatcaaagct gatctttcaa
    26101 ttgaagcaat ttatccaagc tggtttatca tttacgttgg atttggggtc atcactgtaa
    26161 ctgccgggaa cttcttccca cttattggaa aaattttctt ttggatttca ttgatctgct
    26221 atgcgttctt attgccgatc atcatcaaac gtgtcttttt cgtaagaaat atggctcatc
    26281 cgacacgtcc gctgattacg atcgttgcag cacctggttc tctttgccta acaggttatc
    26341 ttaaaaactt tgctgaacct aatttttatc ttgtcgtagc attgttcgct ttatctcaag
    26401 tattgtattt cgttgtgctg tctatgcttc cacgtttgtt caagcttcgt ttttatccaa
    26461 gctatgcagc ctttacattc ccgcttgtta tctctgcaac agctatattt actactgttc
    26521 attacttcaa cagtttaggt atctatagta gcgtattgga tttcttaaaa gttgcggaat
    26581 gtctgtttgc aagtgtagtt gtcttctacg ttcttgctca ttacgtacgt ttcttaatta
    26641 aagaacatag caaacatgga aaatttgttt ctaaaaaaat cgcttaataa tcgattcaat
    26701 aggttgtgaa aaagctgttc tgcatcaagt aataagaacg gccaaacaaa aacagctgtt
    26761 catgtttttg tactggttgg gcttattacc gcagatgcaa gcttttgaac accgtttacc
    26821 aagaggtcgt aa
//
LOCUS       DAFBSV010000034        26448 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.035, whole genome shotgun sequence.
ACCESSION   DAFBSV010000034 DAFBSV010000000
VERSION     DAFBSV010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26448
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.035"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(25..822)
                     /locus_tag="LLB18_001319"
     CDS             complement(25..822)
                     /locus_tag="LLB18_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HBK5244330.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(819..2003)
                     /locus_tag="LLB18_001320"
     CDS             complement(819..2003)
                     /locus_tag="LLB18_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBK5244331.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(2028..3275)
                     /locus_tag="LLB18_001321"
     CDS             complement(2028..3275)
                     /locus_tag="LLB18_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBK5244332.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            3490..5235
                     /gene="dnaX"
                     /locus_tag="LLB18_001322"
     CDS             3490..5235
                     /gene="dnaX"
                     /locus_tag="LLB18_001322"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBK5244333.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            5255..5569
                     /locus_tag="LLB18_001323"
     CDS             5255..5569
                     /locus_tag="LLB18_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBK5244334.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            5594..6190
                     /gene="recR"
                     /locus_tag="LLB18_001324"
     CDS             5594..6190
                     /gene="recR"
                     /locus_tag="LLB18_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBK5244335.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            6254..6898
                     /locus_tag="LLB18_001325"
     CDS             6254..6898
                     /locus_tag="LLB18_001325"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HBK5244336.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            6913..7242
                     /locus_tag="LLB18_001326"
     CDS             6913..7242
                     /locus_tag="LLB18_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HBK5244337.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            7256..8194
                     /gene="holB"
                     /locus_tag="LLB18_001327"
     CDS             7256..8194
                     /gene="holB"
                     /locus_tag="LLB18_001327"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBK5244338.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            8230..9054
                     /locus_tag="LLB18_001328"
     CDS             8230..9054
                     /locus_tag="LLB18_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBK5244339.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            9047..9394
                     /locus_tag="LLB18_001329"
     CDS             9047..9394
                     /locus_tag="LLB18_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HBK5244340.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            9463..10335
                     /gene="rsmI"
                     /locus_tag="LLB18_001330"
     CDS             9463..10335
                     /gene="rsmI"
                     /locus_tag="LLB18_001330"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBK5244341.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            10444..11565
                     /gene="dinB"
                     /locus_tag="LLB18_001331"
     CDS             10444..11565
                     /gene="dinB"
                     /locus_tag="LLB18_001331"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBK5244342.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(11619..12221)
                     /gene="nrdG"
                     /locus_tag="LLB18_001332"
     CDS             complement(11619..12221)
                     /gene="nrdG"
                     /locus_tag="LLB18_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBK5244343.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(12536..14725)
                     /gene="nrdD"
                     /locus_tag="LLB18_001333"
     CDS             complement(12536..14725)
                     /gene="nrdD"
                     /locus_tag="LLB18_001333"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HBK5244344.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            15024..15818
                     /locus_tag="LLB18_001334"
     CDS             15024..15818
                     /locus_tag="LLB18_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5244345.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            15808..17850
                     /locus_tag="LLB18_001335"
     CDS             15808..17850
                     /locus_tag="LLB18_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5244346.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            18131..18280
                     /locus_tag="LLB18_001336"
     CDS             18131..18280
                     /locus_tag="LLB18_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HBK5244347.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            18291..19805
                     /gene="dltA"
                     /locus_tag="LLB18_001337"
     CDS             18291..19805
                     /gene="dltA"
                     /locus_tag="LLB18_001337"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HBK5244348.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            19802..21007
                     /gene="dltB"
                     /locus_tag="LLB18_001338"
     CDS             19802..21007
                     /gene="dltB"
                     /locus_tag="LLB18_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBK5244349.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            21052..21285
                     /gene="dltC"
                     /locus_tag="LLB18_001339"
     CDS             21052..21285
                     /gene="dltC"
                     /locus_tag="LLB18_001339"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBK5244350.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            21288..22556
                     /gene="dltD"
                     /locus_tag="LLB18_001340"
     CDS             21288..22556
                     /gene="dltD"
                     /locus_tag="LLB18_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBK5244351.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            22697..23779
                     /locus_tag="LLB18_001341"
     CDS             22697..23779
                     /locus_tag="LLB18_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBK5244352.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            23779..24582
                     /locus_tag="LLB18_001342"
     CDS             23779..24582
                     /locus_tag="LLB18_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBK5244353.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            24652..25392
                     /locus_tag="LLB18_001343"
     CDS             24652..25392
                     /locus_tag="LLB18_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBK5244354.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            25403..26407
                     /locus_tag="LLB18_001344"
     CDS             25403..26407
                     /locus_tag="LLB18_001344"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBK5244355.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
BASE COUNT         8331 a         4697 c         5478 g         7942 t
ORIGIN      
        1 ttgcgaacat tcatttagca atttttagaa acttctgccg ccaccgccaa aagtcccgcc
       61 accgctagaa tgggtagtac ttccgccacc gccgcttcca ggaggtgggc ttttggggat
      121 tcttcttgtc gtgacaaaag aatttgtcag acgatcggtt ttttcagtta atttgatact
      181 ggatttttct cggaatggat atttgtagat gcctgatttc aattgataac gcgaaacagt
      241 cacaaaataa aagacaagac taaggataag agccaaaaca acagcaatga tgatttctac
      301 tgtcgtcaaa accttatagc gtgtaatttt gccagtttct tcgtctacac gataatgtcc
      361 tcctggaact ccgtcttcca catatgttgc tgatttagac aggtaagctt ttgcagcatt
      421 gtaataggca gcatttgtca tctgatcata aacatcatct aagatcgaat cgattctgct
      481 atcagtcaaa taatcgatca tattaccaga agtcgaaatg tagatttcac gctgtcccat
      541 atctaatagc aatactgagc cattttgatc atttccgact gcgtctctta agtaattatc
      601 agcaaagtct cttggttctt ctgaattaga tgtagtcgtt acgatcaaga ctcgtccttt
      661 gattttttca ttcagctttt ctgcctgttg ttccaaagat tggatttgat ctgttgtgaa
      721 taacccagcc tcatcattta ccgtagctgt atctgcatga gtagccaccg gccagccaac
      781 acttactagc aaaagaaaga ataaaaaaaa ttttttcatc atatcaagta acctccgatc
      841 agaaagagga tcgctagccc agcgaaaatc ccaagagcgg tcagtcccaa ttttttctgg
      901 ctgatcggca ggacaccgct gacctttcct gtttgtccat tcattgcgta gtagtagact
      961 tttttacttg agtcattgct tcgataagta acaagccata ccggcagtaa tacgtaatta
     1021 tttacttcgt ttgtgattga agcagaagtt cgcacaccgg tcaatgttgt atatccattt
     1081 gcggtatctt ttaacagctt ctctgaatag tcttttaatt cagattgaat ctgtgatttg
     1141 attgcctcat attcgatatc tcttttttct gcttggaacc cggctaaata ctggctttta
     1201 aaatcaattg ctttatctaa cgggaaaggt tgcacgcctt cgaccatctt ttgttgcgta
     1261 ttttttgata aggcattttt tactagttct ttaaaagaaa gcttgcctgc tcttgaaaca
     1321 gcaaattgct tcgtttctgt gtattcgatg tcacctatcc gccatatgcg gataactgta
     1381 ccattcgcct gcatggcacc atctacttca gcatctgtag cccaataagg gaaatacaca
     1441 cctgtcaact tatcgatttg atccttattg aaaaaagctt tgggaacaaa ccattttttc
     1501 ttggtccaag cgagaaatct gttgattgct tcttctttct cgacagcaaa aggaagtact
     1561 ttatttggca agaattctcc gcttaaacgt cccgatagta cgacgggatt atggcagtag
     1621 taacaataag tcgcagcagt tgtcgcatca gtcacgatct ctgcaccaca gttgggacaa
     1681 agaaaaagat ctatcgctgc ggtattatct gcagattcgt ccgctgtatc tgaaaaaccg
     1741 cctgcctcgt caaccgcttt gcgctcggct tcattcatat cggcaagctg ttcttgggct
     1801 gtaaaagtaa aatcttcggt aggtgaaggt tcttctttgc tttcttcgcc agccatacgc
     1861 gcttcttttt gcttttgctc atattggctg acttcttctt ctgtatagat attcaggcag
     1921 tattcgcaat gaaatttttg gtctttggga tcaaaagtca acggaccgcc gcaattagga
     1981 catttatgtg taagaacatc catcagctgc acacctttct aaataaatta attaacgggg
     2041 attcctttaa acggtttacc acagtttgga cagaatttag ggatgccgtt ggaaagatcc
     2101 acgatctcat tgcattcact gcatcgcatt tgtagcttag gctgaacgtt ttctacaggt
     2161 ttggcagctc cgcagttgga acagaatttt ccggaatttt ctgtcccgca aactggacat
     2221 gtccaagtat ccgcatttcc ttgtgcagtt tgttgatttt gtttttctgc ttgttgtttg
     2281 atttgttctt ggttattttg agctgcttga gaaagataag aaccatttgc attcattccc
     2341 atacctacac ccataaagcc ggtcattgct cctgcttcat tttttccggc tgcttccata
     2401 ccacgtgcaa tggaaccttg cacgtatcct tcacgtacgc taggatcacc tagcatcgcc
     2461 ccttcgttac gcatattgat cagtttcaca gaatcatcgg tgtaagaaat gctggctaca
     2521 gccacagaaa caatctccat cccacgtaat tcacgccaag aatcatccaa tgcagtatcc
     2581 atgtatttgc ttaattccaa actcttagat ggtacataag aaatccgttg accatctgca
     2641 gacatctgat tgattgctga ttgtagcgct gttaggaatt cagctaaata ctgctcattg
     2701 atatcattga tttccacttg tgttttgttt ttagggattg cgtttgtata aaataaaatc
     2761 gggtcaacga catgaataga ataagtgcca tgtgcccgta agaataattc tgcgttatag
     2821 aaattgtcaa agtagttcaa cggcgcgctt gtaccgaatt tgattccctt tatttcttgg
     2881 agattgatat aaaaaacttg ttgtttctgc ggtgtgacgc cgccaaattt gaatcggtca
     2941 aaagtttcag caattgcttc tttcagtgtt ccattgaaca tggaaggagc tgcgtcattt
     3001 ttaatggtgt aataaccttc ctcagcggta taatcgatga tttttccacc atcgaccaaa
     3061 agcatcatca tgtttggata gacatggacg actgttccgt ctgttaaaac atcttctgtt
     3121 cctttacgat tggagccacg tttgtcatct ttgcggactt tgacaccttt tgtcatgacc
     3181 gttgtatcac tcatattgtc tggttcgatg acttctagcc attgatctgc cagaccgccg
     3241 ccaaccatac ttgttgctgc tttgataaga cccataaaaa attcctcctc tgattcagct
     3301 agtgccaaac aattattgtt tatttattat accataggaa gatgtgaaac ttctcggact
     3361 agagacggaa ttgaaatgga aaattgcgta ttgtttaaat acctgaaaaa gccgagaagg
     3421 atagtagttt ttttacctaa tatcacgtat aataagagat agtgaatttt ttaaaaaagg
     3481 gggatcctta tggcatatca agcactttat cgagtctggc gttcgcagcg tttcgaagac
     3541 atcgttggac aaaaagctgt gacacagaca ctaaaaaatg ctattgtttc ccacaaaacc
     3601 tcacatgcct acttgtttac aggacccaga ggaaccggaa agacgagtgc agcaaagatt
     3661 ttcgcaaaag caatcaactg tccgaacagt aaagacggtg agccatgcaa cgaatgcgaa
     3721 atgtgtcgat caattactgc tggtacgcaa gaagatgtga tcgaaatcga tgctgccagc
     3781 aataacggag tcgaagaaat ccgatttatc cgtgatcggg caaattatgc gcctacaaag
     3841 gcagcgtaca aagtgtacat tattgatgag gtacatatgc tttcaacagg agctttcaat
     3901 gccttgttga aaacattgga agagccaaaa gaaagtgtca tattcatctt agcaacgacc
     3961 gaacctcaca aaataccagc tacgatcatt tcacggactc agcgatttga ttttaaacgg
     4021 atcaatacgg cagatattgt cgaacatctt gaatttatct tgaaagaatc gactatcagc
     4081 tatgaaccag ctgcattgaa tgtgattgcc cgttctgcag aaggcgggat gcgggatgca
     4141 ttgagtattc ttgatcaggc aatctcgttt agtgaaggaa caattacttt agatgatgcc
     4201 atgcaagtga caggtagctt aactgacgaa atgatggaca gttacttgag tgcttgcgtg
     4261 aaaaaagaag taccagaagc attggaaaca ttgaaccaaa ttctcgcagc cggcaaagaa
     4321 tcacgtcgct ttctagagga tatgttacaa tactgccgtg acttgctgat gtatcagcaa
     4381 gcacctaacc tagttgagga acaatcgagt acgatcagaa gtacatttac agaattggca
     4441 caaactgttt cagcggatca gctgttttca atgataaaga ttttgagcga tactcaaaat
     4501 gaaattcgtt ttaccaatag tgccgctatt tatttggaag tcgctacagt caaacttgca
     4561 cagctaccgt ctgcttctgt tccttcagca gatgtagcat ttgcagatga tcagatagta
     4621 aaacagctac aacaagagat taaggaacta agaaacgaaa tcaaggaact acgcagtaat
     4681 acaggaattg agaatacaaa agtacagccg gtacagcaaa caaatcataa aaaacagaca
     4741 agtacctatc gtgtaccgac ggaacgagta tataaagttc tgcgggaagc gacaagacag
     4801 catctgaacc aagtaaaaga agtatgggaa gacttgctga tgagtctatc tgtcactcag
     4861 cgagcaatgc ttaaagcaag cgaaccagtt gcagctggac ctacaggact agtgattgcg
     4921 tttgattatg agattgtttg tcaaagagca gcaaatgacg aagaattgca gctttcggta
     4981 cacaacaact taagccgaat gatcaaagat tatgcgcctg atcctgttta tattacaaga
     5041 gaaagctggc cagaacttcg aagaaattat ttgacgcagg cacaagaaga gggaacagaa
     5101 aactcttttg cttctgaaga ctcagaagga gaaatcgagt tgcttcctca agaacaagaa
     5161 gtaccagaag aaacacttgt agtaaaagca gaggaactgt ttggctccga agctgttaca
     5221 gtggtagatg attaataaaa aggagtagat aattatgatg cgtggaatgg gcaatatgca
     5281 aggcatgatg aaacaagtac aaaaaatgca aaaagaaatg gcagaagcac aagagctgct
     5341 aaataaaaca gagtttacag gtaaagccac caatgaattg gtcaaagcgg tttttacagg
     5401 cgatcgtcgc atgaaagata tccaaatcaa tgaagaagtc gttgatcctg atgatatcga
     5461 gatgcttcag gatcttgtcg taatggcagt caatgatgcg atcgcacaaa ttgatgtgga
     5521 aactgagaaa aaattaggga aatacgcaaa aggtttgcca ggattttagt tttaaactga
     5581 aggagtaatg aatatgcaat atccagaacc aattgcgaaa ctgatcgaca gctacatgaa
     5641 acttccagga atcggtcaga aaacagcgac aagactcgcc ttttatacga tcgatatgaa
     5701 agatgaagta gtaaatgaat ttgctaaatc tttgttaagt gtaaaacgcg atttgcattt
     5761 ttgtagtatc tgcggaaaca tcacagaaga agatccctgc gaaatatgta gaaatccttc
     5821 acgtgatcga agcgttatcc tagtggtcga agagccgaaa gatgtaatgg caatggaaaa
     5881 aatgcgagaa tatcacggac tttatcatgt tctccatggt gtgttatcac cgatggaagg
     5941 gacaggtcca gaagacatca atatttcttc tctgttgcag cggctgcatg atgcagatgt
     6001 aaaagaagtg attatcgcaa caaatgcaac aacagaggga gaagcaacag ctatgtatct
     6061 ctcacgtctg atcaaacccg caggtatcaa agtgactcgt ctagcacatg gtctgtctgt
     6121 aggctctgat atcgagtatg cagatgaagt tactttattg aaagctgtcg aaggaagacg
     6181 tgagttataa atttctaatt aagtgttttt tcagatacaa tataaaagca gcacaagaga
     6241 tgggggcaac aatgtgaacg gactatttat tacaatcgag gggcctgatg gtgcaggaaa
     6301 aaccagcatc ttgaatgaac tttaccctct tttgaaagaa gtagcaaaaa cagaaatcat
     6361 tcaaacaaga gaaccaggag gcattccgat tgctgaagag atccgagcag tgatccttga
     6421 tccaaaaaat gatcggatgg atgaacgtac ggaagcactg ctttatgcag cagcaagaag
     6481 acaacatcta gtcgaaaagg ttctgcctgc tctggcaaaa gggaaaatcg ttttatgcga
     6541 tagatttgtc gacagttctc ttgcttatca aggtgcaggc cgacgcatcg gcgttaccga
     6601 gattgctcgg ttgaatgagt ttgctacaga aggtactacg ccggatttta ccctttatct
     6661 tgacgtagat tcagacaccg gattaagaag aatcaagaaa aacagacaaa atcaaatcga
     6721 ccgtttagat tcggaaggtt tggaattcca ccagcgtgta cgtcatgctt acttaaagct
     6781 ggcagaagag aatccggaaa gaatccacaa agttgatgca agaaaaagct ttgaagaagt
     6841 gctgcaaaca agttatcata caattattga acagtatccg caattttttg aaaactagga
     6901 aggtgaacgt ttatgaaaat tattttagcg attatccaag acaaagacag caaccgttta
     6961 tcaaatgaat tgattgatgc aaatatccgt gccacaaaac tatcatcgac aggcggcttc
     7021 cttaaggctg gaaacagtac gtttatcgtg ggtattgaag atgaccgtgt agaagaagca
     7081 ttggaaatca tcaaaaaaac gtgtgaatca agaaagcaat ttgtatctac acctgttaca
     7141 ctggatattt cgatggatgg gggcgtccct tatccagtag aagtagaagt aggcggtgcc
     7201 acagtcttcg tcttacctgt tgaaggattc catcaatttt aggaggagct gagctatgaa
     7261 tcaagaaata aacttggctc aaatgcaacc gatcgtgtat cagcagcttc aacggagttt
     7321 tgagcatggg cgtatcgctc atgcttatct ttttgaaggg gagaaaggaa caggaaaaca
     7381 tgaagtaggt atatggcttg cacagcacct gttctgtacc caaatgaaag acaatctgcc
     7441 ttgtggaaaa tgcaacaatt gtcagcggat cgaaaagaaa gaacatccag atgttttggt
     7501 tattgaaccg gaaggacaaa ccatcaaagt cgatcagatc agacgtttgc agacggaatt
     7561 cagtcgcagc ggttacgaat caagaaaaaa agtttttttg atcaaagaag ctgaaaaaat
     7621 gaatagcagt gcggcaaaca gtttgttgaa attcttggaa gagccccctg gagatttttt
     7681 agcggtgtta gaaacagatg cagtaggaag aattctccct actattcaat ctcgttgtca
     7741 agttctgcat tttcaagaac tttcgaaaga agcactgatc catcgattgc aagaagagca
     7801 gattccattg gaaaaagcaa aacttttggc tttcttaaca aacagtttag gaaaagcagt
     7861 tgaaatctct caagatgaat ggtttaatga tgctaaggac ttgatttatc aatggttcgt
     7921 ttacttgcaa aagcaagata ctcaagcctt tatctatgtc caaaaaaaat tggtaaaatc
     7981 atttaaagaa aaaacacaac agtttacagg attatctgtc ttgatgtttt attatcagga
     8041 agcacagcgt caagcagtag caaacggcga atatggcaaa gtgaaacaga taaaccagat
     8101 aattgaacgg atattgatcg cagagcagaa actacgcagc aatgtcagtt ttcaggctgt
     8161 tgcggaacag ttcgttttgc atacgatttt ttagcttgcc gcaaaggatg atgatcaagg
     8221 aggatggaaa tggtagaagt agtaggtgtc cgatatagag atgcaggtca tatctattat
     8281 tttgcaccag gagactctga atatgtttat agtgacaagg tattagtcga atctcagcaa
     8341 tccttacata ttgctactgt tgtccttcct aaaaaagaga ttgatcccaa tgaccttcct
     8401 gaagctatcc gtccgatctt gcataaagcg tcacaagctg aattagaaaa agacaaaaaa
     8461 aacaaaaaag atgcttatga tgcattgaaa atcgcaaaag aaaaagtgca gttgcgtgag
     8521 ttggaaatga aaatggtcaa agccgaatac acatttgatc gaaataaatt gattttttct
     8581 ttcacagcgg acgggcgaat tgactttaga gaattggtaa aagatctggc cgctgtattt
     8641 cgtactcgta ttgagcttcg acaaattggt gtccgcgatg aagcaaagat aataggcgga
     8701 attggtccat gtgggcgtcc attatgctgt tcttcttttt taggcgattt cgtgcctgta
     8761 tcaatcaaaa tggcaaaaga tcaaagttta tctttgaatc caacaaaaat ttccggttta
     8821 tgcggacgct tgatgtgctg tctgcaatat gagagcgaag aatacgagac agcgaaaaaa
     8881 gaactccctg actttggaaa agtaattgct acacctgatg gtaaagggaa agtcgtaggg
     8941 ttgaatctgc ttagccgtat cgttagtatt cggctgactg gacgggaaaa tcctgtcgaa
     9001 tatgaatggg atgaattgaa agaatttatc caagtaggtg agatgaatgg ataagagatc
     9061 attatacgac ggattgaatc aattagaatc agagttgaga aatacattaa cagaacttgt
     9121 tgaaatgaag catgctttgc atgagatcgt agaaaaaaat acaactttgg agatggaaaa
     9181 tcaacgtctg cgggaacacc tgcgggaatt gaaccaagtt gcacaagctc cagctgaaaa
     9241 tgtgaagcag gaactttcta agtctcgtat gaatcttgaa aaaatttatg aagaaggatt
     9301 ccatgtctgc tacgatttat atggatcaag aagggacaat gacgagcctt gtgcgttttg
     9361 tctagaagtg atctatcgcg aaagcggtcg atgaccaata acaagaggag actggagcgg
     9421 agaaatactg ctccagtctt tttattaagg agattgtgac agatgtataa tcaaaaaagt
     9481 ttcaagggaa atccggtata tggggattta tatcttgtac cgacgccaat tggaaattta
     9541 gaagatatga gctacagaag tgttcgtatg ctgcaagaat ccgatcttat cgcaagtgag
     9601 gatacgcgta atacacaaaa gttattgaat cattttgaaa tccatacacc ccaaaaaagt
     9661 ttacatgaac ataattataa agaacgtgtc cctcaattga ttgctttgtt aaaagaagga
     9721 aaaacgattg ctcaagtcag tgacgcagga atgccttcca tcagcgatcc tggacatgag
     9781 ctagttttag cctgcataaa agaagggatt tctgtgatct ctatcccagg acctacagct
     9841 gggatgacgg ctttgattgc ttcagggcta gtgcctcaac catttttatt ttatggcttc
     9901 cttccacgta agaaaaaaga acagaaagaa acattgaaaa agctaaaaga acagacagtt
     9961 acgctgattt tttatgagtc accttatcgg atcactgcta cattgacgaa tttcttagaa
    10021 atttttggaa atcgccaagt cgttttgtgt cgggaattga caaaggtcca tgaagaatac
    10081 cttagaggaa gtacggaaga gctactcgct tatatcgaag aacatccagt aaagggtgaa
    10141 tgttgtctgc ttgtagaagg gaatttgttc gaaatgccag tgacggaagt tgatgaagag
    10201 ttgggaacgt taaaggaaca agtagaagca aagatcgctt caggcgaaaa accaaatgct
    10261 gctatcaaag cagtagcgct gaaaaatggg ctgaaaaaac aagaagtcta ccgtcagtac
    10321 catgaattag actgagatag tataagttgt ctataatgaa agactaatga ggaaatcagc
    10381 tactaacttt tcaaatctct tgaacgcgaa cgaatgttct tgtataatga ataagaggtg
    10441 aggatgatgg agctgcaatt tcctttacat aatgatacat caagaaaaat cattcatatt
    10501 gatatggatg cttttttcgc ttcggttgaa gaacgagatc atcctgagtt tcgcggacat
    10561 ccattagtaa ttgccagaca ccccagtgac actggtgggc gtggagtagt gactacagca
    10621 aattatgaag caagaaaatt cggaattcat tcagcaatga gtgcacaaaa agcgtatgag
    10681 ctttgtccgc aagccatctt taagcctggc gaccatcata aatacagcga tatttccaaa
    10741 caagtacggg aagtattcta tcgttataca gatattgtgg aaccagttag tatcgatgaa
    10801 gcgtatcttg atgtgaccga aaataaaatc aattgcaagt cagccatcaa aatcgcccga
    10861 atgatccaag cagatatttg ggagagtgtc cagctaacat gttctgcggg agtaagttac
    10921 aataagtttt tggccaaatt agcatcagac tatcaaaaac ctagaggaat cacggtagtt
    10981 gcccctcaag acgctgtgcc atttttaaaa gctttgccaa ttgaaaaatt tcatggggta
    11041 gggaagaaaa ctgtacctag aatgcatgag ctagggattt atacaggaaa agacctatat
    11101 gaatgcacag aaatgatgtt gattcgaaat tttggaaaaa tgggctattc tctttatcgt
    11161 aaagtcagag gaatccatga ttctccagta aacgttacaa gagagcgaaa atctgtggga
    11221 aaagagcata cttatgggca gccgttgcaa acggaagaag cagtgctgac tcagttgcgc
    11281 caactagctg aaaaagtaga agaagcactg agaagagtcc aaaaacatgg gaaaacagta
    11341 gttttgaagg tcaggtacac ggactattct actgtgacca aaagagtgac attgccagaa
    11401 tatatctata aaaaagaagc actcttttat caagcaagcc ttatatggga ggaaatcttg
    11461 ggagtagaaa aaggaatccg attgttaggg attactttga cgaatctgga cccgatgact
    11521 tatgaaaaca tcgtccttcc attatgggaa aatcaagaaa tataaaaaca gctttgagag
    11581 ttgaaaccgg aaatccgttt tctctcccaa agctgttttt atatcaagtc ttgctttttg
    11641 atttgttcat aggtttctgt tgcatccgta catttttccc aaatcacaac ttgattggat
    11701 tctaaagatt tttggacgtc aatgatccgc tggttgctac ttccgcgaaa ttgtagtttt
    11761 aggtcacgtt tgcttaattc aaagcgtccg tcaacaagga tatcgatttg cgaaaggagt
    11821 tctaatttat cttctgaatc ttgtagcaat tcatcaaagg tatagcctgt ccatgaccag
    11881 atatcttttg tcgtaccgaa ctcttttcgg atacgtcgta cgacttgcag acaaacatct
    11941 gtattcaaaa aaggttcgcc accaagtaaa gttaatcctt gcacgtaatc gttgcgcaag
    12001 tcagcgatga tttgttcttc taattcaggt gtgaatggtt tgccatatcg gaaattttgt
    12061 gcagctttgt tgaagcagcc ttcgcaggca aataagcagc cactaacgta aagactgttg
    12121 cggacacctt caccatcgac aaaattaaac ggtttgtagt cagcaatata gttttggctg
    12181 tagtcttttg ctaaccattc ttttggtttt ggatttctca taaaaaaact tctttcattt
    12241 aaggttcaaa gatatagcta ttgaagataa aatctactcg accacataaa taagaacaaa
    12301 ctgacctaaa tccattgttc aagaaagctt gttcttattt tgatagaggg cgttcaaaga
    12361 tacaaagcca tcgaaagagg gtggtgaaaa aagacttgtc atagcctctt attctgaata
    12421 aacggtgttc aaaagcttgc atctgcagta ataagcccaa ctaaacgaaa aatatgagga
    12481 actatttttg tttagctatt cttattactt gatgcaggac agctttttca caacctcatt
    12541 tcatgtgttt cacacgtgag gaaatttctt tatggcggcc atgtaccatc ggacgagctt
    12601 gcggatttcc taaatagcca caagtacgtt tgactacatc acatgttttt ggatcatgat
    12661 ttccacattc tggacattcg aaccctcgtt ctgtcggttt gaaatcacct tcgaaaccac
    12721 attgatagca atgatcgatt ggcgtattcg taccaagata cccgattttg tcatatgcaa
    12781 aatcccatac agcttctaaa gctttcggat tttgttggag catagggtat tcacagtagt
    12841 ggatgaatcc acctgaacaa tattttggat aatccttctc aaattccaat ttttcaaatg
    12901 gcgttgggtt tttacgcaca tcatagtgga aactgtttgt ataatattct ttatctgtga
    12961 tattttcgat gatgccgaat ttttctgtat ccaaacggca gaaacggtca gttagacttt
    13021 cacttggagt tgaatagaca ctgaaatgat aaccatattc atccccccat gcatctgcat
    13081 tagcttttaa ttctttgacg atatcaagtg tgaaagcttt tgcttctggg tttgtttccc
    13141 attcgccacc gaagaaagct gaagcaactt catacaatcc aatgtagcct aacgatacag
    13201 tagctcgacg gtttttgaat aattcattga cagaatcggt acgtgaaaga cgtttcccga
    13261 aagcaccata catatataaa attggcgcat ttgctggaat ggcttcttta caacgttcta
    13321 cacgatagag aagcgcatct ttcatgattt ctaagcggtc agacagtaac tgccagaatt
    13381 tattctgatc tccttttgat tcgatcgcga ttcttggcaa attcaatgta acaacaccta
    13441 aattcattcg tccgacattt acttcttgac cattttcgtc tttccaccct tgcaagaatg
    13501 aacgacagcc cataggtact ttgaaacttc cagttaattc aacgatttta tcgtaattca
    13561 gaatatcagg atacattctt ttcgttgcac attccaatgc tagttgtttg atgtcgtaat
    13621 taggatcttc agggtttaag ttcacacctt ttttcaaagt gaagatcagt ttagggaaga
    13681 tagctgtccg cttttcactc cctaatccat tgattcgaat ctgtaaaatt gctttttgaa
    13741 tttctctttc aaaccagttt tctcctagtc caaatcctaa tgaagtgaaa ggagtttgtc
    13801 catttgaagt aaataaggta ttgatttcat attccaaact ttgcatagca tcgaagatat
    13861 cttttttggt ttttgctttt gcatattctt tttggcgttc tggcgaatcg atccattctt
    13921 ccgcgtcttt tagatgtttt ttatagttca attctgcaaa aggagcaagc aattcatctg
    13981 ttcggtcggc agaacagcca ccatattgac ttgacgctac attggcaata atctgtgaga
    14041 tttgtgctgt ggcggtctgg atagattttg gcgattcgac ttcggcattg ccgattttga
    14101 acccattgtt cagcatgcct ttgaaatcaa tcaagcagca attcgtcatc ggtgtataag
    14161 gatgataatc caaatcatgg taatggatat cgcctttttg atgcgcattt gctatatgtg
    14221 gtggcaacat tttcagtccg attgattttc caacgatccc ggctgtcaga tctcgctgtg
    14281 tattgaaaac attactgtct ttatttgcgt tttcgttcac gacagtttgg tccttgttga
    14341 ttagcttttc aatcgaaaag ttgatatctg ttgctttact gcgagcaaaa tctcgtttgg
    14401 tacgataatt gatgtactct tctgctaatt catattcgtt tttttctagt aatatatgtt
    14461 ccacgatgtt ttgaatctca tagattttga cattttcagc aaaccggctt ttgatttctt
    14521 ggacaaccaa gtctgcaatc atttgaattt tttcataagt aagtggtgat aatgagccgt
    14581 gaattttctt ttctgctttg atcagtgctt cattgatctt ttgttcatcg aaatcaacat
    14641 ggcggccatc gcgtttgatg actttcatct gggatgtctc tggctgctga gtaacgacag
    14701 ttttttcttc ataatttact ttcattatct tcaactcctg ctaaattgtt cttgtctatc
    14761 ataaaacaaa atcggggaag gagcaactaa atatcggcta tatatagtat tcaatgtgct
    14821 gtataattgg atttctatac tatatgtagt gtatatttta ttgtgaaaaa aggtgaaaac
    14881 ttgtagctgg tggatttgtt ttttgcatat ttaattttgc tgaataaaat aattgaataa
    14941 aattttttat tcagtccaag taaaagtgac aaaaacataa gagcaaatta ttcgtagata
    15001 tgctactatg caaataaata gaaatgaaaa atgaaagagg aggagaagaa ttggaaaaga
    15061 tgatcgaagt gaaacatcta agtaaaagct acggcagcaa actttctccc gtcaaagcct
    15121 tagataatat ctcattcaca gtagaagaag gcgagtttgt tgggattatg ggcccaagtg
    15181 gtgcaggaaa gacaacgctg atgaatatct tgtccacgat caatttgcct acgatgggca
    15241 gtgtctcgat ccaaggaaaa gaaatcacaa aaatgaaaaa cagtgagctc agtgactttc
    15301 gtcgaaaaaa actaggattc atttttcaag agttcaattt gatcgatacc ctaaatgcaa
    15361 aagacaatat cctattgccc ctagcagttg aacggatgac taaagaggaa atggaaaaga
    15421 gagtaagaca tgtagctcaa ttgttgaata tagaagaact gctcaaacgg tatcccgatg
    15481 aactttctgt cggacagaga caacgaattg cagctgctag agcacttgtt gttcagccac
    15541 aagtgatttt tgcagatgaa ccaactggct ctttggactc gaagtcggct acagaattgt
    15601 tgaactactt gaagaccatg aatcaaaaag aaaaagcaac gatactgtta gtcacccatg
    15661 atccatatac agcaagctac tgcgatagaa ttttatttat taaagatggt gtgatttttt
    15721 ctgaagttgt cagaagaggg acaagaagag agttctttga gaaagtaata gacatgcagg
    15781 cgacgattgg cggaggagga aaaatgaatg ctgtataaac tagccgttaa aagttttttt
    15841 cggcagtcac gaggctatct tgtttatttt ttcagtttga ctttatccgt aatgatctat
    15901 tattccttca gcgcaatgac ctacgatcaa tctttagtca gaagagcaag tcaagatact
    15961 tcgatagatg gtggattgag ttttggtgga tttatcatta ctgttgtttt gctttttttc
    16021 gtattcagtg ccaaccgatt tttcttgaat agaaggcaaa aggaaatagg catctatcag
    16081 ctttttggta tgaataaact gcagatatca ggtatatatg tgttagaaat catgataatt
    16141 ggattgttcg cctgtatttc tgggatatta ctcggtatta ttttttccaa actcttttca
    16201 atgattttgg ttcgaatgat ggatatggat cttactagtc cattttttat ctccattcca
    16261 tcagtagtag atactttatt tgcttttttc atcatccttt tagcagtatc tgtatattca
    16321 atatggaaaa tatggcgcta tccaatgatt cgaagttttg gagaaaaaga acaagcagat
    16381 agttcaacaa tgcgcttcag gacaaggcac cgattactcg cagtcatcgg gttactactt
    16441 ttaacgagcg gatattttgg agctagtcat tttagggaaa tcacttcatg gatgatcagt
    16501 tatcattatc ttgatacatt agttttcttt tttccttttt taattttttt cgtttgtgtg
    16561 gtcggtactt atttgttttt ctgttataca ttccggttat ttttgatcat attgagtaaa
    16621 tggaagattt attactatgg tatcaatttt ttgataatgg gtaacacgca agttcatttg
    16681 ctcaaaagtt ggcgtacaaa ttctctgatt acagtcattc tcggaatttc tttaatgaca
    16741 attggcggca cggctagtat ctctactatt ttatcctacc aggagaaagt ttcctccccg
    16801 atggactatc agtttgatgt tgagacagag aaaaaaatca agccgattct agcagaggaa
    16861 gggcagaaga taactaaaga aatcaccttg cattataaag tcattgggag tatctatagt
    16921 caaaatctcg aagaacctat gtttcaaact gctaatctga tcacggaaac acaatatcaa
    16981 gccttcagaa aagttaatcc agatttgccg aacatttctt tgaaatcacc tggtcatact
    17041 gttttgcttg atcaaatgca aactcttttt cggaatattt cattatatgg atctagtatt
    17101 ggactgccag ataatcaaga attgaagatt caacaaatgc ttccaagtgt attaggtgac
    17161 gaaacaatgg tatatctaag tcctgtactg attgtagatg ataccgtttt tgaaaaagca
    17221 aaaggtgtgg attatcaagt agtcaatgta gatgtatcag gtggaaataa tgaaaaaata
    17281 gatgaacgac tgagcaatga cctgtcgata aagtggctca atgctgttta ttattcttat
    17341 gatatcgtaa atggaagtct acaaggagaa attagcacaa agaaacttcc ggatgaccaa
    17401 atgaaggaag cacaatttag ccaagaaagc tctcgtttga atttctcttc cagctattcg
    17461 aaattgcgtg cagttaatcg gcgaatcggt atcaatattt ttgtcacact atttgtcggg
    17521 atgatcgtga ttattgctac tggtagtatt ttgacagtcc ggcaattagc agaagcagag
    17581 gaagaaaaag aaaattatca cctattgact aagctgggga ttccacaaag aaggatcaga
    17641 cggatgatct tcgagcaaaa cgcacttacc ttctttccac ccatgatatt agggatcact
    17701 cacgcagtat ttgcaatcaa tgtcttcact cagtatataa aaactgccga ttactggttg
    17761 gcttatcttg tgagtggctt attgatcctt atctatcttt tgctttatgt cattacgagt
    17821 cagttatatt gtcggattat cgaggaatga tatacggaat aagacaagat aataaataga
    17881 actaaatttt gaataccatt tatttggaat aagaggttgt gacacgattt ttgtcacaac
    17941 ctctttattt tttatatttt ttaaaagtac gagaaattat aaagaaaaaa gcagtgattt
    18001 gatgtgctat ttttataaaa gctatgtgac aaaactgtta gtaaaaaaac ggtttctgta
    18061 agctagacac atgtttcttt ttgtcaaaat tagttacact ttgtgtgagg ttatatgagg
    18121 agggaatcca atgaacaaat ggcgttctaa tccaaaattg aattattggg gaaaattcat
    18181 cattcgaaca attttttata gtgcagtact gctgttcctg atttatctgt atcactataa
    18241 aaatattcaa ggaggaactt ttatctataa cgaattttag gaggaagagt atggaaatca
    18301 aaacgattat tgaagcaatc gatgattggg gaataaatga acctgatcga gttgcttatc
    18361 aggcggatga gacgcatact tttggtgaat tgaaacaagc atcagacgca cttgcttatt
    18421 atttagaaaa aaaggtagaa ggcgatggac caattgtcgt ttttggcaat ttggagtttg
    18481 aaatgattgt ctcatttcta ggggttgtca aatctggcca tgcctatttg ccgattgaag
    18541 agcatacacc caaggagcgt atcctatcga tctttcgggt ggctaaacca tctatggtca
    18601 tcagtatcgg ggactggata gaagatattc cttcggttcc tgtcataaca aaaaaagaat
    18661 ttcaagaaat caagaagata ccagtaggat tttatcccag aaatagcgta aaaggtacag
    18721 aaaattttta tattattttt acttctggta ctactggaga accaaaaggc gtacaaatca
    18781 gtcatgataa tctagtcagc tttgttcaat ggacgatgga agactttggg atcaagcctg
    18841 gtatgcattt cttagcccaa gcgccatttt cttttgattt atcggtattt tctatttatc
    18901 ctgcattagt ttctggcgga atgctgaagc cgttaaataa agcagttgtt caagactttc
    18961 gtcaattatt cgcgacattg ccagccttga agttgaatgt gtgggtttct actccatcat
    19021 ttatggatat ttgcttgatg gaacctacat tcaatggaga aaatgtgccg gaattggaca
    19081 tgtttttatt ttgcggagaa gaattgacga aaaaaactgc agaaagtcta cttgatcgat
    19141 tcccaaatgc acggatatat aatacttacg gtccaacaga agcaactgta gctatttcaa
    19201 gtattcagat tgaccagcat gtactagata gttatgaccg actaccgatt ggctacgtaa
    19261 aaaaagacac gaaagtttct attgtccaag aaggtaaacc tgtttcaaaa ggagaaacgg
    19321 gtgaaatcat tattgcagga ccaagcgtat caaaaggtta cctgaacaat cccgaaaaga
    19381 cagctgctgc gttcttttgt caaaatgact tagcaagtta ccatacaggg gatgcaggta
    19441 gactagatga atatgggctt ttattttatg aaggacgtat ggatcagcag gtcaaattac
    19501 atggataccg gattgaactc ggggatatcg aacattatct gctccaagac aaccgaatca
    19561 aacaagctgt cgtcgtacca aaataccaag gaacaaaagt acagcagctg gttgcttttg
    19621 tcgtattaga aaacaaaacg aaacagccgg attttcagtt gactaaatct atcaaagaac
    19681 aattactaga agttgtaatg gattatatga ttcctcagaa gttccattat gtcgatctgc
    19741 tgcctcagac agttaatgga aaaatcgatc gaaaaaaatt aacagctgag gtgaatcctg
    19801 aatgatgtta cctcatatga tcccttatgc agagccgttt tatttttttc ttttagccat
    19861 tgcgcttgta ccgatcgttc tatctttatt gatatgggaa aaaagattac cagtttatca
    19921 atcagcagtg acacttttct ttttatttgt cagctttgga ggtaattatt ggcaacaggg
    19981 agcggcgctg attgggtatg ttttgtggca gacgatactt gtatggggct attttgttta
    20041 tcggcaaagg aaaaatcaga caggatggtt ttttgccgcc gttattttag cgataattcc
    20101 actgttttta acgaaagtga ctcctttttt tgaacatgga aaagcatcgt tacttggttt
    20161 tttaggaatc tcttatttaa cctttaaatc tgtacaaatg atcatggaaa taagagatgg
    20221 catgatcaaa acatataagc catttcgtta tatccagttt ctgctgttct ttccaacaat
    20281 ctcttctgga ccaatcgatc gctataggag atttgaaaaa gatcagctcc atccgcctgt
    20341 tcgtgataaa tatgttgatc ttttgggaaa aggcgtccaa aatatttttg tcggtttttt
    20401 atataaattc attatcggtt attattttgg tcaagtactg cttcctgtag tgggacgcat
    20461 tgccttacag catggtggta tttcatgggc attagtaggt tatatgtacg tgtacagtat
    20521 gtatttgttt tttgattttg ctggctatag cttatttgca gtcggtacaa gctacatgat
    20581 gggatatcag acaccaatca atttcaataa acctttttta tcatggaata tcaaagaatt
    20641 ctggaatcgt tggcatatga cgctgtcctt ttggttccgt gattatgtat atatgcgatt
    20701 gatgttcttc atgatgaaga aaaaattttt taaaagcaag atcgtaatgt caaatatcgg
    20761 ttattttgct ttgtttcttc taatgggtat atggcatgga ttgacgtggt actacatcgt
    20821 atatggactg tatcatgctt gtctgatctg tctgacagat gcatggatcc gatttaagaa
    20881 gaagcataaa gagcagttgc cttctaacaa atttacgcat ggcttagccg tatttttgac
    20941 atttcaagca gtatgtttta gcttcctgat tttttcagga tttttagata aacttttttt
    21001 tagctaacga atagtgacat attaatttat ataacaaagg agaaaaggaa aatggaagaa
    21061 caaattttat caatcttaga agaaataaca ggaacagatg aagtaagaaa aaatcgtgat
    21121 attgatctat ttgatgaagg gttgcttgat tctttagcat ctgttcaatt attagtcgag
    21181 ctagacggag agctggatat ccaagtccct gtatctgaat tcgagcgaga ggattggagc
    21241 acaccgaata aaatcattca acaagcaact gcattgaagg gttgagtatg aaaaagaaac
    21301 tttttgctat tttcggcccg gttgttttag ctgttggctt actgtttgtg ttttttacct
    21361 cctcctatca agtagatatc tctaatccag aaacgattag acgtgcctct tcttccatgt
    21421 cagtgaacgt gttgaaagga gatgcgataa aaaattatgc attatctgaa aaacaatata
    21481 ttcctttttt tggctcaagt gaattaagca gaatcagtcc atttcatccg tctgttctgg
    21541 cagaaaaata ccagcgaaac tatcgtccat ttttgctggg agcacccggg acacaatcgt
    21601 taagccaata tatgatgatg cgttctgcag gagatgctat gaaaaacaag aaagtcgtct
    21661 ttattatttc tcctcagtgg ttcgttaaaa atggtgtaaa aactgattac tttaatacgt
    21721 attattctga acttcaaaca tacgactggt tgttttcaat gaagaaagta acgcctgctg
    21781 atcgctattt agctagaaga ttattaactt tctcaaaagt aaaagagaat gatacgttga
    21841 cggcgattct gcaaacgatc aaaaaaggga agctaccttt acctgaatct ttgaatcagc
    21901 tgcgcagcca atggaacatg ctgaagagag aggatgaagt attcagcaat attgggttga
    21961 aagatcgaca gcaaaaaatc gatcatgagt caaaacgatt accaaaacaa taccaagaaa
    22021 cagaattatc cattttagca aatcaaattg gagaacgaga aacgacgaat aatccattcg
    22081 ggttgaaaaa cgatttttat acgcatcgta tccgagccca cgagccagag ctcaaacagt
    22141 cacaaaaaaa ttgggattat cgtttttcgc cagaattttc tgattttcag ctggtcttgg
    22201 atcaattagc aaaaaaccat aacgaagtat tgttcatcat cccaccggtt aacgagaaat
    22261 ggagcgatta taccggacta tctcaagaaa tgttacaagg atttgccaaa aagatcaaat
    22321 ttcaattaaa tagccaagga ttcaatcgaa tagctgattt tgtcaatcaa gcgggtacca
    22381 actattttat ggaagacacg atccatctag gctggaaagg ctggttggct gcagatcaac
    22441 agatcagacc gtttttagaa gaaaatcata ttactgctag taagtatcat cttgacgatg
    22501 ctttttttag caaatcttgg caacatcaaa taccagataa actacaatta aaataaagaa
    22561 aacaggcgag tgttgctcgc ttgttttctt tatttttgaa tattctgaat aaaagataaa
    22621 aataccaagt ttgcctgaac aaaaatcata agcaatggta taatcacaat atgaatatag
    22681 aaatggggga aaacatttgg atacaaaaga agaacagcta cttattgatt taacttctgc
    22741 aaaaggagta cctggaaatg aagaagaggt aagagaagta ttcagagaat atgccaaacc
    22801 attcgctgat gatatttttt atgacggttt aggcagtgtg attgccaaac atggtgctgg
    22861 cggaggcccc aaggtcttta tttctggaca tatggacgaa gttggtttta tggtaacaaa
    22921 aataaccgaa aaaggattct tggaattcca aactcttgga ggttggtggg ggcaagtcat
    22981 gcttgctcag caagttgaaa tcaaaacacg tgaagggaaa atcgtccacg gtgtgattgg
    23041 ttccaaacca ccacatgttt taacacctca agtaagaaat aaaccttatg aaataaagga
    23101 tatgttcatt gatattggcg catcaagcca agaagaagcc aaagagtggg gcatacgtcc
    23161 tggagatatg gtcactccat atattgaata caaacgaatg aatggcagta aatatttact
    23221 ggcaaaagca tgggataatc gtatcgggac agctgtttct ctgcgagtat tagagaatct
    23281 atctaaagaa gcacacccaa atgttttatt cgcaggaagc gatgtgcaag aagaagtagg
    23341 cttgcgaggt gctcgaacaa gtacacacct tgtaaatccc gatattgctt ttgctttaga
    23401 tactggtaca gcaggagaca ctccaggaat gacaccaaaa gaagcagatt cgattttagg
    23461 aaaaggccca cagattttga tttttgatgc atctatgatc ccgcataaaa aattattgaa
    23521 ttttgttatt gatgtagcag aggaaatgga tattccattc caatatacag tgatttctgg
    23581 cggaggaact gatgcaggac aaatgcattt gacaagagat ggtgttccgt ctgtagccat
    23641 taccgttcct gttcgttatc tgcattccca tacatcagtg attcatgaag atgattattt
    23701 gaatacagtg aaactagtca cagaattagt gaaacggctt gatagtgaaa cagttgaaaa
    23761 aattcggagt tatgaataat gaataataga atacctattt ctgaatatcg gaaaaaagca
    23821 cgagtttctt tggaaaatca atggggaatc aatacttggc ttgttttctt atctataata
    23881 tttacgagcg tcatccagaa cttttttgac ggtttcagtc cttttccgga agaaagcatg
    23941 cagcagcact tattgagttt tctagtcgat aatttacttt tattcgcatt caactatgca
    24001 ttgttttaca ttgcgctagt agttgtacgg ggtggcagac caaaaagtaa ccttttattt
    24061 tcagttttcc aaagaaagta ttttggttcg atacttggca tcaatttgat caattcagtc
    24121 atcaactggc tactcaacag tttaatcttt ctgcccatgt ttttaatcag cggagtgagt
    24181 acttatatgc agctgctttt cagttcaaat gcggtaccta cgggtgtcat gccagaagat
    24241 tttcttgata tcagctttgt tttatcgatg atagggatga tttttgtttc agcactcatc
    24301 atgagtattg ttggcggttt attccaattt gctgcatgga caaagttcga ctatcctgat
    24361 ttgtcggtta ttcaatgttt gaaatatggc tggtttttat tgaaagatag aattggtacg
    24421 tatattttgt tgcagctgtc ttttatcggc tggtatttgc taggagcaat cgctttgttc
    24481 atcggtcttt tgtgggtcat tgtttatgtg aatgtgtcag ttgcagaatt ttatgaacaa
    24541 gcacggattg aaaaaggagg tccagacgcc tattttactt agcatgtaag cagtttattc
    24601 atcaaaaaaa taacttttgt ggtaggataa atctttgagg gggaatgtac gatgaaatta
    24661 actgttttag gatgcttagg agcgtatcct tataaaaatc aagggacaac aggttatttg
    24721 cttcaatctg acgggttcaa tttgttgatc gatgcaggta gtgctacgct gatcaaatta
    24781 caagaacacc ttgatccact tgatctagat gctgtgatcc ttagccatta tcatcatgat
    24841 catattgctg accttggtgt attacagtat tactggcaac ttcatcctaa gagaaatccg
    24901 gagacattgc tttcaattta tggacacaca aaagattcca ttcactttga agaattgacg
    24961 ttggaaaatg tctcaaaagg acatccttat tttgaagctg aagaattaaa aattggtcct
    25021 tttctgatta cttttatgga aacaatccat ccagtagtat gttacgccat gcgtatcgta
    25081 gaagaaacaa cggggaaagt attcgtattt acaggtgatt caggttattt ggaaagtttc
    25141 gctgattttg cgaaagatgc tgatttgttt ctagcagata cctatctttt tgaaggaaat
    25201 gaacatcatc atgcccattt cacttcaaaa gaagctggag aacttgcgaa atcagctaac
    25261 gtaaagaaac ttgtacttac acacctacct cagtttggtg atttagaaca attgaaaaat
    25321 gaagcgcaaa aggcagcagg caaagggatt gatatagaac ttgctgcagt tgacaaagtg
    25381 tttaacattt aggaggaaga acatgatttt tgtaccaaat gaaaaccacg acccaagaat
    25441 caatttagca attgaacaat atttgctgca agaaatgcct ttagatgaac ctattttgct
    25501 cttttatatc aatgaacctt caatcatcat cggcagaaac caaaatacgc ttgaagaaat
    25561 caatcgagat tatgtggaag aaaatggcat tcatgttgtc cgtcgcttaa gtggaggcgg
    25621 agctgtctac catgattttg gaaacctgaa ctttagtttt atcatgcctg atgatgggga
    25681 ttcattccgt gactttgcga aagtaacaca gccaatcatc caagcacttc atgaattggg
    25741 tgttgctggg gcggaattga aaggccgaaa tgatctagtc attgatggca tgaaattttc
    25801 tggcaacgcg atgtatgcta ccaacggtcg gatgtttgct catggaacaa ttatgttcga
    25861 ctctgatatc aatgaagtag tcaatgcatt aaaagtaaaa aaagacaaaa tcgaatcaaa
    25921 aggaatcaaa tcgatccgtt ctcgtgtaac gaatatcaaa ccatttcttc cagaagaaaa
    25981 gcaaaaaatg acaacagaag aatttcgtca agaaatcttg ttgaaaattt tcggcgtaga
    26041 gtcagtagaa gaagtaaaaa cgtacgaatt gactgatgaa gattggaaaa aaatcaatcg
    26101 aatctctgag gaatattatc gaaattggga ttggaattac gggaagtctc cagatttcaa
    26161 tttctctcgc caaaaacgtt tttctatcgg ttcgattgaa gtccatttga atgtctcaga
    26221 aggaatgatc aaagaagcaa aaatctttgg cgatttcttc ggactaggag atatctctga
    26281 cgtggaaaaa aaattggttg gacagaaata tgataaagca tctctatcaa aaatagtcag
    26341 ccaaattgat gtgaagaaat attttggtgc gatagaacca gaagaattgc ttaccttact
    26401 ttattgaaaa taaaaaatag cggaatccac atatatggat tccgctat
//
LOCUS       DAFBSV010000035        26125 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.036, whole genome shotgun sequence.
ACCESSION   DAFBSV010000035 DAFBSV010000000
VERSION     DAFBSV010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26125
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.036"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            10..276
                     /locus_tag="LLB18_001345"
     CDS             10..276
                     /locus_tag="LLB18_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5244356.1"
                     /translation="MDTAKKEKYTLRQLRALKGYSKEELSRKSKVTSRTIFIYENDVD
                     KMRNGKYATLEKIAKALGVRVSDIFLDPDSEKPKSITGETKQVS"
     gene            289..447
                     /locus_tag="LLB18_001346"
     CDS             289..447
                     /locus_tag="LLB18_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244357.1"
                     /translation="MEEKNIKVPTLEEYTKIVVETDEQNPKTIAVITANDIESCEGFR
                     VRMTPRYD"
     gene            complement(444..674)
                     /locus_tag="LLB18_001347"
     CDS             complement(444..674)
                     /locus_tag="LLB18_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBK5244358.1"
                     /translation="MGKNQWVSPRNGKWAVRGEGNSEDTKLFDNKSDAVEYGKKISKK
                     QQSEFIVQKKNGQIQSKDSFGNDPIPPRDKEH"
     gene            746..901
                     /locus_tag="LLB18_001348"
     CDS             746..901
                     /locus_tag="LLB18_001348"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244359.1"
                     /translation="MSNKPKITLNGTPNLQRLADEMARIRSRHWGVTVVATIIEQKEK
                     PTQPASK"
     gene            1058..1213
                     /locus_tag="LLB18_001349"
     CDS             1058..1213
                     /locus_tag="LLB18_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244360.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGEKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(1210..1434)
                     /locus_tag="LLB18_001350"
     CDS             complement(1210..1434)
                     /locus_tag="LLB18_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBK5244361.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            1701..2036
                     /locus_tag="LLB18_001351"
     CDS             1701..2036
                     /locus_tag="LLB18_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244362.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            2269..3210
                     /locus_tag="LLB18_001352"
     CDS             2269..3210
                     /locus_tag="LLB18_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HBK5244363.1"
                     /translation="MSKSTLEMSHQEWLEDRKRGIGGSDVATVLGLNKYKSPYQLWLE
                     KTGQIELKDLESEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPVIDGSGATADFLKEKYADVEENQTA
                     LPSRFDELIEQKRELKRTKKEIESSIRQVDNEIISELGKREASIGITQRNIISWKLVR
                     TRRMNTKKLAEKYPDVANDEEIYNVTESRRLTEKEIK"
     gene            3212..4102
                     /locus_tag="LLB18_001353"
     CDS             3212..4102
                     /locus_tag="LLB18_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HBK5244364.1"
                     /translation="MATNESLKNQLAEKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            4145..4945
                     /locus_tag="LLB18_001354"
     CDS             4145..4945
                     /locus_tag="LLB18_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBK5244365.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWSLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADNIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            4960..5811
                     /locus_tag="LLB18_001355"
     CDS             4960..5811
                     /locus_tag="LLB18_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK5244366.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            5808..6125
                     /locus_tag="LLB18_001356"
     CDS             5808..6125
                     /locus_tag="LLB18_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244367.1"
                     /translation="MNLTKQEKRICRQIMLQIIGDRDMDELSQQESRMVRKISKLIGA
                     DTMDRSKPLPKLNFESFTFEKYSHLREVGYSVNAIRKALGVGSSVWAKWRKENVNEVN
                     QND"
     gene            6118..6300
                     /locus_tag="LLB18_001357"
     CDS             6118..6300
                     /locus_tag="LLB18_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244368.1"
                     /translation="MIKLIGKETLKVYYVAETKAEVSRWLLKMFNKTRANASVSQKAS
                     VSETGMPEAMWISRRN"
     gene            6302..6772
                     /locus_tag="LLB18_001358"
     CDS             6302..6772
                     /locus_tag="LLB18_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244369.1"
                     /translation="MAMIPKFRAWDREKDRMIYPSTTGVCFEMNDDGISVLDIDVDYP
                     NDYGFPKIASILMQSTTLKDKNGVEIFEGDIALITHKSTNYADTYWHSYVEVFRAKNG
                     AYRIRGEHIYETELYSNRKQLTVAGNVYNSPELLKRDRFMTTTENPELLKEEQR"
     gene            6769..7311
                     /locus_tag="LLB18_001359"
     CDS             6769..7311
                     /locus_tag="LLB18_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HBK5244370.1"
                     /translation="MNKQELIDKYTAEISRLRPYCPNRHLISDQLKYGLYKEILEDLK
                     QLDEPQKPAVPKFVAEWIEYAKKKGDSLAISFKPWNLYGVEYSKTDRWIEDNQGTFAR
                     AWLIGYEVEKEPLYYVKLPVVYFNHWDLETYLMKDDRGNITIADNNDFDDMKFTESEI
                     KAIDERYWPFAVPVEEVAEG"
     gene            7308..7691
                     /locus_tag="LLB18_001360"
     CDS             7308..7691
                     /locus_tag="LLB18_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244371.1"
                     /translation="MSNLKVGDIVFYKGDEGIIREVMTDGKENFYRVDVSRKSILYLY
                     EDELDLGTQKLNDNQKMVFDYLKSNVEQGGKSVMYSIFLLGDWDSRIGAARNVDIAYC
                     GLNGKQEAEVLSAFAQWGLEQEEAE"
     gene            7688..7918
                     /locus_tag="LLB18_001361"
     CDS             7688..7918
                     /locus_tag="LLB18_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244372.1"
                     /translation="MKYEIPLSEADVQSIINGREVNKKLPDGTELVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSIDDTFRLGS"
     gene            7925..8128
                     /locus_tag="LLB18_001362"
     CDS             7925..8128
                     /locus_tag="LLB18_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HBK5244373.1"
                     /translation="MNNRHRRITKLRKQELNVLKTKFEKEYGISAEETYKVASQCVAD
                     ASNAIRKFGISILNDDRKWEEMR"
     gene            8125..8421
                     /locus_tag="LLB18_001363"
     CDS             8125..8421
                     /locus_tag="LLB18_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244374.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKVKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWTAKSKENLAVVRLVDIELINDK"
     gene            8498..8911
                     /locus_tag="LLB18_001364"
     CDS             8498..8911
                     /locus_tag="LLB18_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBK5244375.1"
                     /translation="MQLLREVAFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGKIIAYK"
     gene            8924..9310
                     /locus_tag="LLB18_001365"
     CDS             8924..9310
                     /locus_tag="LLB18_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244376.1"
                     /translation="MWKDYVSLKELKKDLIFKKIVEWSESELILEDGTKMEVVCSESD
                     CCAWAEGEFKNVKLDAVITDIKIFDKGNRLYNGDGHSSYAEVVVYHNRNEIAKAECTA
                     NDGNGGYYYSVCALKVKEKLCVVTDA"
     gene            9802..9874
                     /locus_tag="LLB18_001366"
     tRNA            9802..9874
                     /locus_tag="LLB18_001366"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9835..9837,aa:Lys,seq:ttt)
     gene            10260..10520
                     /locus_tag="LLB18_001367"
     CDS             10260..10520
                     /locus_tag="LLB18_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244377.1"
                     /translation="MNHEKFIEKCKAIVRERIENEIADLSGAVPEFSVFIVWSCKTLQ
                     NSKALVSASLKGAPYFEITLNGDKGEIYVDTYLKKSNECIKV"
     gene            10563..10736
                     /locus_tag="LLB18_001368"
     CDS             10563..10736
                     /locus_tag="LLB18_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244378.1"
                     /translation="MKQYTAKDFEEMKRLKKDYEEVDMELTVGVIQRRLRVGLETAKA
                     IYNDLNAIEEKNG"
     gene            11125..11958
                     /locus_tag="LLB18_001369"
     CDS             11125..11958
                     /locus_tag="LLB18_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small subunit of terminase"
                     /protein_id="HBK5244379.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELKSNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPVGNKNALKTGEYET
                     IFFETLSDEEKDIYSSLNDNPSFVLSEEIRLLKIRQFRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKNPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            11951..13366
                     /locus_tag="LLB18_001370"
     CDS             11951..13366
                     /locus_tag="LLB18_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HBK5244380.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPENMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTTVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            13378..14907
                     /locus_tag="LLB18_001371"
     CDS             13378..14907
                     /locus_tag="LLB18_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBK5244381.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEDMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKDPTAKAEYVTKNLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            14825..15877
                     /locus_tag="LLB18_001372"
     CDS             14825..15877
                     /locus_tag="LLB18_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBK5244382.1"
                     /translation="MTIETKYWTKRRELEDQARLKQENQTLKKLTSVFPEALKEIQAK
                     LLSQADLHNITYPEMMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            15879..16196
                     /locus_tag="LLB18_001373"
     CDS             15879..16196
                     /locus_tag="LLB18_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244383.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            16323..16946
                     /locus_tag="LLB18_001374"
     CDS             16323..16946
                     /locus_tag="LLB18_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HBK5244384.1"
                     /translation="MSMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            16961..17851
                     /locus_tag="LLB18_001375"
     CDS             16961..17851
                     /locus_tag="LLB18_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HBK5244385.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLFGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            17874..18089
                     /locus_tag="LLB18_001376"
     CDS             17874..18089
                     /locus_tag="LLB18_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244386.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            18101..18442
                     /locus_tag="LLB18_001377"
     CDS             18101..18442
                     /locus_tag="LLB18_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244387.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            18442..18813
                     /locus_tag="LLB18_001378"
     CDS             18442..18813
                     /locus_tag="LLB18_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244388.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            18806..19201
                     /locus_tag="LLB18_001379"
     CDS             18806..19201
                     /locus_tag="LLB18_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBK5244389.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGAVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            19203..19580
                     /locus_tag="LLB18_001380"
     CDS             19203..19580
                     /locus_tag="LLB18_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244390.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNKPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            19581..20189
                     /locus_tag="LLB18_001381"
     CDS             19581..20189
                     /locus_tag="LLB18_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBK5244391.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            20189..20530
                     /locus_tag="LLB18_001382"
     CDS             20189..20530
                     /locus_tag="LLB18_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244392.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            20772..23561
                     /locus_tag="LLB18_001383"
     CDS             20772..23561
                     /locus_tag="LLB18_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBK5244393.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANSFVLIIGAVVGAI
                     AVFGYFMATNEEFRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNEIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWID
                     LKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVN
                     SAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTI
                     KGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTP
                     SVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQ
                     MKRDAGAVGGTLYAT"
     gene            23551..24291
                     /locus_tag="LLB18_001384"
     CDS             23551..24291
                     /locus_tag="LLB18_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBK5244394.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYRNVTRKIECYYKAPSIDVVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            24288..>26125
                     /locus_tag="LLB18_001385"
     CDS             24288..>26125
                     /locus_tag="LLB18_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBK5244395.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCEIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLAEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRLIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     SLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFTSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSAGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWR"
BASE COUNT         9485 a         3735 c         5518 g         7387 t
ORIGIN      
        1 gaataaaata tggataccgc gaagaaagaa aaatatacat tgagacaatt aagagcttta
       61 aagggttatt caaaagaaga actgtcaagg aaaagcaaag tgacatcaag aacaatattt
      121 atttacgaaa acgatgtaga taaaatgagg aacggaaagt acgccactct agaaaaaatt
      181 gctaaggcat tgggtgttag agtttccgat atttttttag accctgattc ggaaaaaccg
      241 aaatcaataa caggtgaaac aaaacaagtc agctaggagg tgtgaatagt ggaagagaag
      301 aatataaaag taccgactct tgaagaatat acaaaaattg ttgtcgaaac agacgagcag
      361 aacccgaaaa caatcgcagt tattacggcg aatgatattg aatcatgcga aggttttcga
      421 gttcgaatga cccctagata tgattaatgt tctttatcac gtggaggtat aggatcgttt
      481 ccaaaactat cttttgattg tatttgtcca ttcttttttt ggacaataaa ctctgattgc
      541 tgttttttag aaatcttttt accatactca acagcatctg atttattatc aaatagtttt
      601 gtatcttcgg aattaccttc accacgtaca gcccatttgc catttctagg agatacccat
      661 tgatttttac ccataacaat tcacctcgct ttcaagttaa ttctattaag aggtgaaaag
      721 aaaacaaact gatggaggtg agattgtgag taacaagcca aaaatcactt tgaatggcac
      781 acctaatctt caaagattag cagatgaaat ggctagaata cgttctagac attggggagt
      841 tactgtggtg gcaaccataa ttgaacaaaa agaaaagccc acacagccgg caagcaagta
      901 gtgggcacca tagaacaata atattatatc acacactcgc cacttccgaa aagaggagtt
      961 gctgctctcc tttcaagttt gccaaagtcc acgtttcttc attttggcaa ctcctcttct
     1021 tggaggtggt gacggcgaga gacgaaggag ggatgacatg aaggaagaat caaaaatagg
     1081 gattttgaat gagaacaatt acacaagatt aattattgaa acagaagaag gggaaaaagt
     1141 agcagaagtt acattgaccg atgcaactcc tgctgacggt tatcgtattc gattaactcc
     1201 taaatatgat taaccttttg gtgggtgtgg atcgtttccg tgactatcac ggctttgaat
     1261 ttttccatct ctgccatgaa taaatagctc agatccttga tttttagaaa tctctctagc
     1321 gatttttact gcttctgatt ttgtattagt atgtgcagtc gctttagaat ttccagcacc
     1381 tttgacattc caaccaccat tggaattagg tacaacatgt tgattttttc ccatagtttt
     1441 cacctccatt tctatagaaa tattttatca aatagaaatg gagaaattca ataaacgaaa
     1501 ggagggatca aatgacatta caagagcatc aacacttgat gcgaaaacta aatcaggaat
     1561 accacgagga aatgaaacct agattgctag gggaacaatg gcgtgaacgc cagaagaagt
     1621 ggttagaaat aaaaaagtga ctcagccgtc caaagcaatg agtcacaaac caaaaattat
     1681 acctaaggag attttatcac atgaataaga aaattgaaaa tcttatcgaa gaattgaaac
     1741 gtgaatgcca aaagcaaggt gtttctatta tttgtacagc ccaaaaagaa ggggaactta
     1801 aaagtctcgt ttatggtgag acaacagaaa ttttactttg tcttgctatg caagaagaac
     1861 atttagatga aaatctccca ttgtcagcac atattatgcg tagaattgct gtggatgctt
     1921 acgaacaagc gaaaaatgaa gaagaaaatc aaccttcaaa tcatactttt gttattaata
     1981 acaaggaaga tttagctgat gtgatgactc gtattctcaa gggggaattt caatgatgaa
     2041 tgaaaaaaca attgatctac tcattatttt atttttcacg ttagtgattg tagcgaaaag
     2101 ttatgtaatc tttggcttgt tattcgcaat taccatgctt gtgctttgcg tgttagcaag
     2161 cagaaaagag gttaaacatg aacgagttag caaatcttga caactattta actgatcctg
     2221 attatgctaa accaccatat gaagcgccaa ttgatgagga ggatgaagat gagtaaatct
     2281 accttagaaa tgagccatca agaatggctc gaagaccgca aaagaggtat tggtggctca
     2341 gatgttgcaa ccgtacttgg attaaacaaa tacaaatctc cttatcaatt gtggcttgag
     2401 aaaacgggtc aaattgaatt gaaagattta gaaagcgaac cagcttattg gggtaatgtt
     2461 ttagaagaag tggttgctaa agagtttcag gaacgtacag gcaaaaaagt acgcagaaga
     2521 aaccaagtat ttgaacatcc attacatcca tttttaagag caaatattga tcgggaagta
     2581 gtgggagaaa atgccattct ggaatgtaaa acagccaatc aatttctcgg aaaagagtgg
     2641 gaaggtgaag aggtaccgct tagctatctc tgtcaagttc agcattacat gaacgtttta
     2701 aacaaagact attgttatat cgctgttttg atcggtggac aaaaattcat ttggaagcgg
     2761 attgaacgag atcaagagct gatcgataca atcactgaac aattagtaga gttttgggaa
     2821 acgaacgttc ttggaggtat cgagcctgta attgacggaa gtggagcgac tgctgacttc
     2881 ttaaaagaaa aatatgcaga tgtagaagaa aatcaaacag ctctaccatc acgttttgat
     2941 gaacttatcg agcaaaaaag agaactcaag cggacgaaaa aagaaattga atcatctatt
     3001 cgtcaagtag acaacgagat catcagtgag ctaggtaaac gtgaagccag tatcggtatc
     3061 acacaaagaa acattatcag ctggaaactt gttcgtacaa gacggatgaa cacgaagaaa
     3121 ctagcagaga aatatccaga tgtcgcaaat gatgaagaga tttataacgt tactgaatca
     3181 agaaggctaa ccgaaaagga gatcaaataa tatggcaaca aatgaatcgt taaaaaatca
     3241 attggcagaa aagccacaga aacaagttgc accaggacag ttagggctta aagctctaat
     3301 gaatacacca acaatgagaa agaaatttga agaagtactt catgacaatg ctaatgcttt
     3361 tatgtcgaat gttatgactc ttgtatctaa tgacagttat cttgcagata gtgaaccgat
     3421 gtctatcatg agtggtgcgt taactgctgc aacattaaat cttgggctag ataagaattt
     3481 aggttatgca tatttagttc cattcaatag taaaaacaag caaacaggaa aatgggaaaa
     3541 gaaagctcaa ttcatgcttg gctataaagg atatatccaa ttagcccaac gatcaggtaa
     3601 atacaaagca ttaaatgtga tcgaagttta cgaaggagaa ctaaaaagct ggaaccgact
     3661 gacagaagag tttgagtttg atccaaatgg tagaacgtct gatgaagtca ttggatatgt
     3721 tggctatttc gagttactga atggattcaa aaaaactgtc tattggacca aacaagaaat
     3781 cgaagctcat cggattgcta acaataaaga tcgcgataag acaaagttaa gtggtgtgtg
     3841 ggcatctgat tacaatgcaa tggcacgaaa aactgttttg agaaatcttc tttctaaatg
     3901 gggaatcttg tccatcgaaa tgcaagaagc caccacatcg gatgagagag tccaaagggt
     3961 tcaagaagac ggcagcatta ttgctgaaac agaagttgaa gaagatattc ctgaaagaaa
     4021 agaagcagag gttatatctg aagaaaatga agatgtacaa actggattat ttgatgcatc
     4081 taatccgccg ttaaacaaat aatgagggag ctttctccct tgcttttcta gaggagaaat
     4141 acgaatgaac acaggatatg tcaaattaca tcgaaaagtg atgaattcat tcgtttggac
     4201 caatccttat atgtataaat tatggagctt gtgtttgatg aaagcgagtc atgagaatcg
     4261 caagatactt tttaatggaa aagagataca agtgaacagc ggagaattcg tcacagggcg
     4321 cgatgctatc acatctgaga tgaacgaagg cgtgaaacgt gaacatcaag tgaacagcgg
     4381 ttctgtatgg agatggctaa aacaatttga aaaaaacgga atgttgaaca tcaaatcaac
     4441 tacgaaatac agcgttatat caataaaaaa ctggtctttg taccaaagca gtgaacaaca
     4501 aatgaacatc aaacgcacaa caagtgaaca acaagtgcac acaaacaaga atgaaaagaa
     4561 ttataagaat gaaaagaata ataaaacatc atcgtcgcaa ccacgcaaaa agcgtgttta
     4621 cgacaccgac tcagtttact acattctcgc ggaggagtta ttcaaacaga tttgtcagaa
     4681 tcaggaaatc aaaaagccga atctgcaaag ttgggcagat aacattcgga aaatgatcga
     4741 gatcgacaag cggaccgaaa accaggtacg gggaatgatt gaatggagtc agcacaatgt
     4801 gttttgggca tcgaatattt tatctgctaa aaaattgcga gaaaaatacg acacaatggc
     4861 agcgcaagca aatcgtgatt ataaaacaaa acaaactaaa acgcttgaat acgagaaatt
     4921 tagcacagat gagttgccta tttgagagga ggcgtaggca tggaaactgt tggggaaatc
     4981 atggaaaagc tgatacagaa agtgcttgtc caacgtggcg aatgtcctga atgcggacag
     5041 cctttgtatg gatggcgtac gaagaaccct gatggctcag aacgttgtaa gccaacctgt
     5101 atgcaatgtg ggtataaagc attgcgagtt caggaagact tacaaacaga acgaatttac
     5161 aacgagagcc tgaaagcaag agcaatcaat tttttcaaag gtggttctgt tgtgcctaat
     5221 caagcgttgt ttgattgcac attgcagaat tatcaaattg tcgatcaaga aacaagacaa
     5281 gcggttgaag taaccaaacg ctttgttaat tcagtcttgt taggaaatcc aagtcacctt
     5341 gttttaactg gaaaacaagg aacaggtaaa agtcacctag cgatggcagc ggcttgggaa
     5401 gtcttgaagc gatcaaacta cgataaaaaa atcttattta tcgggttaca ggaaatgctg
     5461 gatcaaatca aattttcgta caacaatcct gaactcagaa aaacgattga gggatcgttg
     5521 attgcagata tcaaaacagc ggatttagtc atcattgatg atatcggttc agaactagga
     5581 aaagatgcat cagatagtcg agcgtttggc ataaacacgc taaattcgtt cttggatgca
     5641 cgacagaacc tagcaacgat tatcacaacg aacttgcttg gtgaagaact gaaaaaagct
     5701 tacggtacga gaacaatatc aagaatgttt gtcaactctg atggatttac gatggtattt
     5761 tctcaaacag cagacaagcg cataaaacca gtcaaaggag cgatcgcatg aatttgacta
     5821 aacaagaaaa aagaatctgt cgtcagataa tgttgcaaat tataggtgat cgtgacatgg
     5881 acgaattatc tcaacaagag agtcgaatgg ttcggaagat aagtaagcta atcggtgcag
     5941 atacgatgga tcgatccaag ccattaccca aactgaattt tgaatcattt acgtttgaga
     6001 aatatagcca tctgagagag gtaggctata gtgtaaatgc tattcgaaaa gcacttgggg
     6061 taggaagtag tgtatgggca aaatggcgga aagaaaatgt aaatgaggta aatcaaaatg
     6121 attaagctaa taggcaaaga gacgctcaag gtttactatg tagcggaaac aaaggcagaa
     6181 gtcagccgtt ggctattgaa aatgtttaat aagactagag ccaatgcttc agtaagtcag
     6241 aaagcaagtg tatcagaaac aggcatgcct gaagcaatgt ggatttcaag gaggaactga
     6301 gatggcaatg ataccgaagt ttagagcgtg ggatagagaa aaagacagaa tgatttatcc
     6361 tagcacgaca ggagtttgtt ttgaaatgaa tgatgatggt ataagtgtgc ttgatattga
     6421 tgtagattat cccaatgact atggttttcc caaaatagct tcaatcctca tgcaatctac
     6481 cactctgaag gataagaatg gtgtggagat atttgagggg gatatagcgc ttatcactca
     6541 taaatcaacg aactacgccg atacttattg gcacagttac gtagaagttt ttagagcaaa
     6601 aaacggagcc tacagaattc gcggtgaaca catctacgaa acagaattat atagtaatag
     6661 aaaacaattg acggtagcgg ggaatgttta taattcacca gaacttttga agagagatcg
     6721 atttatgact actaccgaaa atccagagtt attgaaggag gaacagcgat gaataaacag
     6781 gaattgattg ataaatatac tgcagaaata tctagattaa gaccttattg ccctaataga
     6841 catttaatta gcgatcaact taaatatggt ctttataaag aaatcctaga agatttaaaa
     6901 caactagacg aaccgcagaa accagcggtg cctaagtttg tggcggaatg gatagaatac
     6961 gctaaaaaga aaggcgatag tctagctatt tcattcaagc cgtggaacct ctacggtgtt
     7021 gagtatagca agactgatag atggattgaa gataatcaag gaacgtttgc tcgtgcttgg
     7081 ctaattggct acgaggtcga gaaagagccg ttgtattatg tgaagttgcc agttgtgtat
     7141 tttaatcatt gggatttaga gacgtatcta atgaaagatg atagaggaaa tataacaatt
     7201 gcagacaaca acgattttga tgatatgaaa tttacggaat cagaaataaa agcaattgat
     7261 gaaagatact ggccatttgc tgtgccagtg gaagaggtgg cggaaggatg agcaatctta
     7321 aagttggaga tattgttttt tacaaaggtg acgaaggcat catccgagaa gttatgacgg
     7381 atggaaaaga aaatttttat agggtagatg tcagcagaaa atctatactc tacctgtatg
     7441 aagacgaatt agatttaggt actcaaaaac tcaacgacaa ccagaaaatg gtgtttgatt
     7501 atcttaaatc aaacgttgaa caaggtggca aatcagttat gtattcgata ttccttctag
     7561 gtgattggga ctctcgaatt ggagcagcaa gaaacgttga tatagcttac tgtggattaa
     7621 atggtaagca ggaagcagaa gtcctatcag cattcgctca atggggatta gaacaggagg
     7681 aagcggaatg aaatacgaaa taccactaag tgaagcagac gtccagtcaa ttattaacgg
     7741 tcgggaggtt aataaaaaac ttcctgatgg tactgaatta gtcatcagac aaagttattt
     7801 gaaagatatg gcagctccag tattaattga tcgttttaac gtgactgatt ctgtggtaga
     7861 gaaccattta aaagaatttc gatcaagtat agacgacact ttcagattag ggagttgatt
     7921 gacaatgaac aacagacatc gcagaataac aaaactaaga aaacaggaac tgaatgtact
     7981 aaagacaaag tttgaaaaag aatatggaat ttcagcagaa gaaacatata aagtggcaag
     8041 tcagtgtgtt gctgatgcga gtaatgctat tcgtaagttt gggatttcga tattaaatga
     8101 tgatcgtaaa tgggaggaaa tgagatgaaa ctaaaagacg gattttacgc tagtagtcac
     8161 ggcatcggcg gtttaatgct agatatgccg acaaagaatc ctaaaacacg taagaaacca
     8221 aaagtcaaag tcggtgacat ggttcgctgc gaagcagaag ggttcatcta tccatttcgt
     8281 ggatatgtag aacacgtcta taatcactca gcaatcattc gtattgaaaa cacgatggaa
     8341 tgtgataaat ggacagctaa aagcaaagag aatttagcag tggtgagatt ggtggatatt
     8401 gaactaatca atgacaaata aaaaagccgg atcgctccga ctgattcaat aaattccaca
     8461 agtttattat atcacataaa aggggcggtt tgacttgatg caattgttac gagaggtagc
     8521 tttcaaacag acaagatgta atgcgagaga tgtgctgaag aactttcggc gtttggagcg
     8581 gatggcaggt cgctctttga tagatattaa gtcgccgatt attacggaca tgccgaaggc
     8641 accgaagcac ggcaataagg cagaagacgc gatcattcag atgatggata tagaagcaga
     8701 gagagacgcg attttagcgg ctttgatggc gcttagtctg attagtcgtc agatactcta
     8761 ctacagcttt tgtgtgccag atagcttctc aaactacagg attagccgtg aagtgggtta
     8821 ttcagaaaga agcatacaac ggatgaagtc ggaagctctg atagagtttg cagaagcata
     8881 taaacatggg aaaataattg cttataaata ggaggactat ataatgtgga aagattatgt
     8941 atcattgaaa gagttgaaaa aagatcttat tttcaaaaaa atcgtagaat ggtcagagag
     9001 tgaattaatt ttagaagatg gaaccaaaat ggaagttgta tgtagcgaat cagattgctg
     9061 cgcatgggcc gaaggtgaat tcaaaaatgt aaagcttgat gcagtgatta cagatataaa
     9121 gatttttgat aaaggtaacc gtctctataa tggcgatgga catagttctt atgccgaagt
     9181 cgttgtttat cataatcgaa atgagattgc taaagcggaa tgtacagcaa acgatgggaa
     9241 tggaggctac tattacagtg tctgtgcttt aaaagtcaaa gaaaaacttt gtgtagtgac
     9301 tgatgcataa aaaatggcgg ttttttggcg gaatgatggc ggtttttagc tatttaccag
     9361 tgatattatg gtagtgtcga aagattagtg ataggtctga gacaaaataa aatgtaaggg
     9421 aggaaatctc cctcatcgtt taattaagct tcgatagaca gcagcggaaa tattaagaat
     9481 aaggatgtga attttaactc cttctaaatt gttcttatta tctatcatcc gttgctgtct
     9541 attgttatta tgtcactgtg gcggaaaggg tagacgctta aaaataaggt caatacgtcg
     9601 agggatagcc ttaacgtttt atgatttgac catgcaaggt tcgattcctt gccagcgact
     9661 tagacgaaag gtagcttaaa tattaaccac atcaacatcg tcagcgagtt gataaaggta
     9721 actagcagac tctaggattt aagccagtct taccgattag tctgttatag tagcaagctt
     9781 gctagaggta gctcctctgg ttgacgtgca gctcagttgg tagagcgcct gacttttaat
     9841 caggaggtcg ccggttcgaa tccggtcacg ttaataaaga acctacggaa acaatcaatc
     9901 ttatcggatg ccgattggtt ggctgaatta agcagtgtgt ctgtgaatca gttaataggc
     9961 ataaaatact agcacagacg tgtgccactc tcaggtgtag gttaggagag aaacattagc
    10021 aaccgagggt tggaaatggg cgctcaaagt acacgagcaa ggcgaggtcg atagtaatcg
    10081 atggaatcgg tgtaggttgc tattacataa ttgattgggt tagattgagt tttgggattc
    10141 ggtacaaatg aatcgtcaaa tgactcaagc acaggatcgg aaacgtccct gcctgtgcat
    10201 tacatattag atcactcgtt gagtggtctt tttattttag aaaagagagg attttgaaaa
    10261 tgaatcatga gaagtttatc gaaaaatgca aggctattgt acgtgaaaga attgagaatg
    10321 agattgctga cctaagtgga gcagtacctg agtttagtgt tttcatagtc tggtcatgca
    10381 aaacactaca gaatagcaaa gcattagtca gcgctagctt aaaaggagca ccgtattttg
    10441 aaattacgtt gaacggggac aaaggtgaaa tctatgtaga tacttatctc aaaaaatcaa
    10501 atgaatgtat caaagtctag caggtgctag gctttttctt tacataaagg aggaatgatc
    10561 tcatgaaaca atataccgct aaagatttcg aggaaatgaa gcgattaaag aaggactatg
    10621 aagaagttga tatggagcta actgttggag tcattcaacg aagactgcgg gtcggattag
    10681 agacagcaaa ggctatttac aatgatctaa atgctattga agagaagaat ggctaatgag
    10741 gaactactgg tatatatcgc taactaatga atatcctcga accattgatg attgttcagt
    10801 gcgtgttgtg cgttctgtac aaatcaaagg gaagtactct attgtcgaaa tggggagaga
    10861 agcagaacca tgtgagattg atgcgtgcaa gctcgtttat tgcggtcatg gtttctatga
    10921 tgaaccaaac attcaaaata atattaacaa gaatttgagg gattagaatg caagaaatgg
    10981 cttaaaaatc tccaatcagg acaaatcaag ttagacaaag tttccgattt aaagatatta
    11041 attgaagcag atctaatgtt gaaagatatt gaaaattaga aaacaaaact caacctaaga
    11101 agattgcgag gtggtgtgta ttgaatggca agacaacgtg atccaagacg tgatgaagcc
    11161 aaaagaattt ggttagaatc caacggagaa aagcagttaa aggaaattgc atctgaatta
    11221 aatgtttcag attctcaggt tagaaaatgg aaatcgcaag acaaatggag cgctgaattg
    11281 aaaagtaacg ttaccaatgg caaaagtaac gttactaatc aaggtggcgc tcctattggt
    11341 aatcaaaatg ctaaaggtaa caaaggaaat agccgagctt ctccgccagt gggtaataaa
    11401 aacgctttga aaacaggcga gtatgaaacc atattttttg agacactaag tgatgaagag
    11461 aaggacatct attctagtct gaatgataat ccttcttttg ttttgtctga agaaatacgt
    11521 ctacttaaga taagacaatt tcgtatgatg aagagaatcc aacaagctga agctggacta
    11581 aatgatgaag aagtcgaacg attgcagcag ctaagaaaga ttaaaaatcc gattgaaaaa
    11641 aatggtaaaa agctagaaat caagcgtgag gttatgcaag atgtgcagat tagcagaaaa
    11701 aaacatcgca aaattgatga tattctttca attgaagatt cattgactcg gattagcaac
    11761 cagttagcta aagccatcaa gcaaatgaat gaactttata tgaatgaata cagaactgat
    11821 ttaattaaag ctcagactga taagatccaa gctgagacaa atgaaattgg cggaaataat
    11881 tcaggtgaag aaatagaaga atggaaacag gcagttttaa atgccgcaaa caaacgggcg
    11941 gtgaaagaaa atgaataatg aatttattcc ttttgctgat attggttctg ccattgatta
    12001 ttactatgat aaaccagtag ctttttgcca agatattttg catttgaatc ctgatgaatg
    12061 gcaagaaaat gttttaaatg atttagctga attttcaaag gtttctgttc gttctggtca
    12121 aggagttgga aaaacagcat tagaagcagg agcaatactt tggttcttaa cgtgtcgacc
    12181 ctacgctaaa gtaatagcaa cagctccgac aatgaagcaa ctttacgatg tactttgggc
    12241 agaggtagct aaatggttaa atgatagctt gatcaaaaac ttactgaagt ggacaaagac
    12301 caaaatttat atggttggtg attcagagcg ttggtttgct acggctagaa cagcgactaa
    12361 accagaaaat atgcaaggtt ttcacgagga ccatatgttg attgtggtag atgaagcttc
    12421 tggtgtgtct gatccaatta tggaagctat tcttggtacg ctatcaggtt ttgataataa
    12481 gctgttgatg tgtggaaacc ccaataatat tgaaggtgtt ttttacgatt cccacaattc
    12541 agaccgtgat aaatacagag ttcataaagt atcaagctat gatagtaaac gtacaaacaa
    12601 agacaatata gaaatgattc ttaaaaaata tggaaaagaa agtgatgttg ctcgtgtccg
    12661 tatttttgga gaatttccca aaggtgcgtt ggattcattt atcagtcttg aaacggttga
    12721 attggctaca gaaaaacaaa ttagtgattc tttagtcaat aaaacaacgg ttgctcatat
    12781 tggtgttgac gtagctcgat atggtgatga ttctacgatt ctctttccta gaattgctac
    12841 cagggcattg gagtatgaga agtattcaaa acgtagcacc atggaaacaa caggatatgt
    12901 catcaacatg gccaagaatc taatgagtca atatccgagt attgataaag tgatgattaa
    12961 agtcgatgac actggtgtcg gaggtggtgt aaccgaccgc ctagaagaac ttatagaaga
    13021 caaacattat ccttttgagg tgtttggagt gaataacggt tcaacatcag aagacgattt
    13081 ttacgataat ttaggtactc aactatgggg aaacatcaag gaaatgttag aagaaaatat
    13141 gacagcaaat cttaacggag aacagcctgt tattgaattg ccttctgata gttcgttaat
    13201 caaagaatta agtactcgca aattcaaaat gacaagtaga agtcgtatac gtttagaaag
    13261 taaagatgat atgaaaaagc gaaatattgg tagtcccgat attgctgacg cactggcttt
    13321 agcgttttat gagccaccaa gtcactatca atttattcaa ttttaggagg tgagcttttg
    13381 attagtacag tattatcttt agagagatat aagaagctac gtgttaaata tgcaacacaa
    13441 attgaagatg gaatgtttga tccgaatggt tttatagaag atatgaaacc attttttgct
    13501 gatcgcgaaa gaaaatatct agcttatact agcgaaaaga atgaaataga taatagacca
    13561 aagcctaaca ctgatattgt aaaagttaat aataaacttc atgctggtat gtattcaatt
    13621 gtcgtagacc aagcagtcaa tcattttact ggtataccta tcaaatggga ttacgatgta
    13681 tcggaacaaa aaagaacact cattcaaaga ttaaaagata aattcttaaa aaatgatata
    13741 gaacttccga cagttccaga agcttttaac aaattaacaa gcaatcttga ttccatgaga
    13801 ttcgcaatgc ttgattctga aactgcaact tttcaaggag cttgtggagt agctttccga
    13861 ttgttagagc ctgtggaaga agatgatggt tggaagttaa gagcaagtaa tattgaacct
    13921 tggagagcag aaagatatgg aaatgccgga atctatatca aagaaaagta tgactcttac
    13981 cagaaaaaat tttttcaaga aatgaaagtt atgacaagaa ataaaattct gacatatgct
    14041 tgctatggtg atttgaattt tgttacaagc ggaacgttca aaaaaattga tgagaccgat
    14101 aaccctttgg ggacgattac cttggcagaa tttaaaaata atacgaatcg ttattgtgat
    14161 tttgaagtag ctgaggaaat tggagatgca attgatcgtg ctttgtctga tcaacaaaac
    14221 gaaatcgaac aatttaagct tgcgtacatg cttgttactg gcacaacaat gagcaaaggc
    14281 actgctaaag aaatgatgaa tcagctaggg attatcaact taaaagaccc tactgcaaaa
    14341 gctgaatatg tcacaaaaaa tttagcaaaa gatttcaatg aatatcatat ggatctattg
    14401 aaaaaacagt tttacaccat ttgtaaagca atcgatttta acgatgaggt gtttaaatca
    14461 aacagttctg gagaagctcg caagtggcaa atcattagcc tagaagcgaa aacaaatact
    14521 aaagagcaat attttagaga aggattgaaa gaatgcgcag aaacaattgc tgcttttctt
    14581 aagtttcatg acaaagtaga aattgagcct gaaaaaatta tttttacttt ctctagatct
    14641 ttgccaactg atttaagtta tttagctgaa gctttaccta aacttgcacc atacgtatcc
    14701 aaacgaacta ttcagagcca aattccattt gtaacagatg ttgattatga aaatgaaatg
    14761 atggaattgg aaagtggaag tgcttatcca gatagtgaat acaattttgg cggaggtggc
    14821 aatagtgacg atagaaacga agtattggac caaacgtcga gaactggagg atcaagcaag
    14881 gctcaaacaa gaaaatcaga cacttaaaaa attaactagt gtatttcctg aagcactgaa
    14941 agagatacaa gcaaaactat tatcacaagc tgacttacac aatatcactt atccagaaat
    15001 gatggagttt tatagtacaa gtaatcagaa aaaatatcgt gaatatgtgg aaaaaaatta
    15061 taagtcatta aaaatgtatg atgcaaaata caaagagttt atcgatgaat tttttccacc
    15121 atttgactat gcaaaagtca atcgcttatt acaaatacga tcagatgtat ttaaaattct
    15181 tgcagaatat gcgatggatg cagatgtgaa tcaatatttt tctgatcgct tagaggaaat
    15241 tcttcaaaga acatattctt ctaatgctaa tgtttttgtt caacttttaa acgttgatat
    15301 accaaattat ttaccagaaa atgaaattaa acattatttg aactatccat ggtcaggaaa
    15361 gacattttca agaagacttt ggggaaatat ttcatcgctt gaacagaaac tctctaatgc
    15421 tattgtaaaa agtgttgcta gtggagaagg cgttatacac gcattaaaca ccatgagatt
    15481 agactcagaa atttgtgaca tgtttaagtt agaagaatca aagtataaca aagcgataga
    15541 aaatctcgtt cgaacggagt atgcaaaatt tgcacaagat ggtattgaaa aatcatattt
    15601 agaaacaggt attgaggaat acaacgtatt gactgcaaaa gatgagagag tttgccggat
    15661 ttgtggagga aaggcaagta agaatcccta taaactgaaa gatgctgtca taggtgaaaa
    15721 tcgagcacct ttccatagtc gttgtagatg tacggatgtt cctaatttac caaaattagg
    15781 aaaggatatt gatgaagaat atgaccgttt atttggcgat ttattagatg agtttgcaca
    15841 tgattctttt ggaattaatt tgaaacggag gaagtagaat gaaagatttt tttgaagcag
    15901 tactaacaat taatgtaaat gctgatattg cagaagccta caaaacagct attgagtctg
    15961 agaaccatcc taatggcttg agagaccatt ggaatggcaa ttatgcctac gtggttattg
    16021 gcgatcaaac tgttaattat caagataata ctccagttga taagaatacc gttaatttaa
    16081 cgattcaatt attatctcat tcattaccaa atttaaaaga aacagttgat tggtatgaaa
    16141 agatgggatg tattgttgtt agaactgact acaaagaagg aaagtctagt aattaggctt
    16201 ttttattttg tccgaaatga cgttaaacta gcgcaatact gggcttggtt gaatggtggg
    16261 gcgcaactat taaaactcaa agcaatgcgg ggcgtgaaaa cgaatcgtgg ggcgaaagga
    16321 gaatgagcat gaaacacaaa tcattaatgc caatgaattt gcaatacttt gccgaaggtg
    16381 acgatcaaaa gttttctttt gatgacttca aatcttttgt ggaatccaat gaagaagctc
    16441 aaaaatttat tcagtcacaa tctcaaagtg ttgccgacaa acaattggaa gcttggaaac
    16501 aaaataactt agataaaatt aaacaggata ccatcaagga atatgaggaa tctaagaaaa
    16561 acaagtcacc tgagcaaatt caactggaaa aactacaagc tgaatttgaa gcagaaaaag
    16621 cgttgcgtgt gacaagtgat aataaagcat ttgttgcaga acaaattgct ggattagaac
    16681 tagatggaga gttaaaagag tctatttctc aatttatgct aaataatctt gttagttcgg
    16741 atacagattt cactaagaat gctgttgaag gttttacaag tgtcttgaat gcaattaatg
    16801 agaaacatgc agatgcatta aaagaactac aaatgaagtc tgcatttggt ggaactcaac
    16861 aatcgaataa ccaggttcag cagaacaatg aaacattaac aaatccagaa gaacaattag
    16921 gacaaattct tcaacaattt aactaggaga gtgaaaaatt atgaaaaaaa catctttaaa
    16981 taatttagag tatttggata tttcaccagc gattaatgct atgcaagtac caaatacacc
    17041 ttttttaagc tatttatttg gtgctggaaa aacagagcca gcaaactcga cagaaattaa
    17101 atggcgtgaa tatgatatca acaacgatga ttcttctgaa aaacttgagg gcggagaata
    17161 tccagatgct gaatcaggtc gaacttggtt taacaactat actgaaattt ttagaaaatc
    17221 aacctctgta tctggtacat tagatgctat taatgtgaat ggagtcggaa atgaattaac
    17281 taatcaagta gcactacgtg gtatggaaat gaaaattgat ttgaaccgaa aattgattac
    17341 tggtgtaaaa gctgatgaaa atggttctaa aggtcgtcga atgaatggga ttttgaactt
    17401 gatcaattca gcaaataagg cagaaacagc cactgcgggt gcagtaacaa gaaaagatat
    17461 cgatacttta tttaaattga tgtatgaaaa aggttatatg ggagaaaaac tatgcttgat
    17521 ttctccagat atgcaggagt taatgactga tgagttagat ggaaaatcaa caaaaattgt
    17581 tcagttcggg gaaagagtaa cttttggatt gcaaattgga aatatcgtgt ctaattacgg
    17641 tacaggtatt gctctactag aaccatcatt gccaaaagga acaattgccg caatcgatac
    17701 taattatgtg aaactacgtc cattacgtga atggagagca gaagaacttg caaaaacaac
    17761 ggattctaga cgtatcggtc ttgtaggtga atactctctt gaatacaatg cttcaaactc
    17821 tggggcaatt ttaaatttaa agtctgaata aaagggagtt agtactccct tttttgatag
    17881 gaggaattac agtggtaaaa aaagatgaaa ctaaaaaaga tgaagtcgtg aaatatagag
    17941 taggtaaaac taaaaatttt gttgggtttg ttcatcctaa aactcgtaga tttatcacag
    18001 cagattcaaa taacgaattt atcatttcta tagatgataa agaagcaatt gcaattttgg
    18061 aagatgcaat tgatgttaat gaaatttagg aagtgatctg atggatgaat cgctaaaaac
    18121 ggaaatcatt gagtctacaa aagaagattt tccagatttg agtgaagaac gcataactaa
    18181 tttattagaa ataattttgc tagaaattga atcatacaac acttgtaaaa atgatatttc
    18241 atgggaaaag ttaaaaagcg tgattagtga agtgttgtat aaaataataa aaaatgaatc
    18301 agaaaaaaca gtatcttcag ttagacgtgg cgatacaacg attagttatg cttcaacaac
    18361 aaatgatgtt agtgagttac ttctaggcta tggtgatttg atacgaagag ttattggttg
    18421 tggaggattg gagttttttt aatgaatgaa gcagatattt tagaaactac ttatgaagat
    18481 agttgtatta ttgaaagact gacggacatt gaagattcta atacaaatat tactattcaa
    18541 gattacaaaa aagtatatga taatcctatt tcttgcgctc tttcacaagg tcaaatcgat
    18601 ggactagcag tcatagaaga tggagagatg gtaaatgttt caactgacac atataaatta
    18661 tttgttcatc ctaagattaa actaaaaaaa ggagatcgaa taacaataac tcaaaaggcc
    18721 agtggcttaa ttttttctct atttgctact aagccttttt actatcctag tcattgtgaa
    18781 gtgaatttga taggaagtga gaaaaatggg taatctcaaa tatgaatcaa atgcagaaaa
    18841 gatcattgag aattttaaaa atatgactgt aattgctcaa aaagaaggaa tatccttcgt
    18901 taacgattca atgaataaag tcgttagttt agctaaacca ttaactcctg taaaatcagg
    18961 taatttaagg cgaggatatc gtgtagtaaa agctagaaaa ctatcaagcg gtcgaattgt
    19021 tggagcagtt ataaacaatg aacattattt taaatatgta gaagaaggtc ataggactaa
    19081 aaatggtggc tttgtcaaag ggaaattcat gttaactcgt gcaacgaatc ttgcaaatat
    19141 gtcttatatt cctcgaagat ttaaacaaat ggcaataaaa atcgttaaga aaggaaagta
    19201 acatgaaaga tgaaatcatt gctgcaatca gtagcaaatt aaaagaaatc tatcctgatg
    19261 ggacaatata tcttgattca gttatgcagt caactaaaga tttttatttc gttttatcag
    19321 taatggaatc tggaactgaa aatgtaggaa ttgatattca aaatgtttct ttcttaattg
    19381 atattgcatt gattgataat aaacctaata gaaatttaat taatgaatta gtctcacgtt
    19441 gtgggacttt ttttaatacg attacaatcg atgagcaaat attatttcca aaagcctatt
    19501 tacctgatga agcagatggt gttcaacata ttcgttttac attagaattt ccacaatata
    19561 ttgaatggag tgaaagataa atgggagaaa aaagaagtaa aaccggaatt atttctgtcg
    19621 aaaaacctac ttggtttcct ttggaagatg agacagggaa ttttccggta tatggtactg
    19681 cgttgccaat gggaacagca gtaagtatca aaccaacagc taattatgaa acaacacaag
    19741 attatgggga ttcagtggtt caagatcaat ttacagcttt tggtggtgca gaagttgaac
    19801 tggaagcaaa tggatatact cataaagttt tatctacaat tactggaggg aaaattgtta
    19861 aaggtggtgc cttgcgttct ggagaagata ttgcgcaaga tggtgcgttt gcatatagac
    19921 gtaaaaaatc gaatgggaaa taccgttata cggtctttta taaaggacag tttgctctag
    19981 attcagatga aacatcaacg attgaaggaa gtaaagtaag ttttactcat ccaacttgga
    20041 agggttcatt tgtagatgta ccaggacttg gatatatgta ttcagttgat gaagatgatg
    20101 aaggcgtgga taaagcaatg atcggaaatt ggtttacaaa agtagcaatt ccaattgaag
    20161 aagcagaact ttcaggaggt acagaataat gtcaaaatat caaacaacga ttaaattaac
    20221 gaaaaaagat gaagaaggta aatatgagca agtacaattt aaatctgctg aatttttacc
    20281 aggaacagtt gtagaagatg ctgcaggagt tatggaagaa atgcaaacag cgactgataa
    20341 acaatcagtt aaaaaagctt taagtcgtgc ttattcattt attgcagata ctttatttga
    20401 gggacaattt actggtgaag attattgcaa aggaattgat gctcgtgaga ttgcctcatt
    20461 gacaggaaaa ttattgaagt ctgttactgc aggttttgat gaaacttata cagagacgaa
    20521 aaaaaagtaa gtgaggcgct caagtcacct tcatttaagt attcgattac ttaccgagaa
    20581 ttagatataa agacgcaatt actcgaagca ggttggacgt taccagaaat tgaacgtact
    20641 gacttggatg agttaatgcg tctttttgct tttagagatg cggtaaaaga gcatgaagat
    20701 gttgagtact atgataattt cactcaattt taggaggtga tactttgaat aacgatgacc
    20761 taattctgaa gatgatacta gatgaatctg gttttactgc cggtatgaat aatgctgtca
    20821 aaaagttgaa ctcttttgat gaaacaatcg aaagaaaaag tagaaatagt ggcagttcat
    20881 taggtagtat ttggaaaata tttgctggaa gttttctagc tagcggagta actagaatcg
    20941 taggagctgg ctttgatcta atcaagggtt ccataagtgg agcggttgat cgagtagata
    21001 cgatgaataa cgctctacga aatttccaaa atatgggatt tagtaattca gaaattatga
    21061 agaatatcgg aaagaatggg cttttatctc aaggtattca aggacttcct actgctttga
    21121 atgatgcgat aagtcatgtt caacttcttg cttcttctac aggtgattta actcgttcaa
    21181 ctcaaatatt taaagcttta aatgatggaa ttcttggttt cggtggttca actgatcaag
    21241 ttaatgaagc tgttattcaa ttatctcaaa gtttctcaaa cggaaaagta gacgcacaaa
    21301 cttggaactc aatgatcaac gctcaacttg gacctactct ttctgctatt gctaaaaaga
    21361 tgggaattac aatgggagat ctgaaagaag gtttgtctca aggtaagatt tctgttgaag
    21421 aattccaaaa tcaattaata gaaatggata ccaaaggtgg cggaggactt aaatcattaa
    21481 gtcaaatcgc taaagattct actaagggaa ttaaaacctc tatacaaaat gcaaaaacag
    21541 ctgttacacg tggtgttggt gaggtaatag aaggattaaa taaagcatta gtagattcag
    21601 atttaggtgg atttaaggga attattgata aagtgggcag ttcaatggaa tcgttcttaa
    21661 aagtaattgc tgcaaatatt cctacagcag tatcattttt aagtaattta tttaacgaaa
    21721 ttcaaaaatt tggttctgct ttgaaattca tgatgccctt tcttgttcct gcagctaccg
    21781 cttttggagc gttcatgttt caacttaaag gtataccagc aataataaaa agcttcaata
    21841 attttaagaa tgccataatt ggcgttggaa attcattaaa gattatgggg gcaatagctg
    21901 ctgctaattc atttgtttta attattggtg cagtcgttgg tgcaatagct gttttcggtt
    21961 actttatggc aaccaatgaa gagtttagaa acaaggttat atctatttgg aatgatgtga
    22021 aagattccgt aattggtgta ttaaaaaata taaaggactg gggaattgat acttggaatt
    22081 ctgctaaaga aatggcatca aatgcagttg agggtgtcaa agatgcttgg tcaggaacaa
    22141 aggaatggtt ttctaacacc tggaaaggta ttaaggatgg ggccacaggt ttatttgata
    22201 aaacagtaga gacttcaaga aatgcagtcg atagtgtaaa aaatgcatgg tctaatatga
    22261 agaaatggtt ttctgatact tggcaaagta taaaagattc agccagagaa aaatggaatg
    22321 aaattaaagg ttctattatg tcggttgctg gtccattgat tacaggtata aagaatgcat
    22381 ttttacatgt tactttttat ctagagacct tatggaataa tttagttgag attggtaaaa
    22441 acgtctttga gattttaaaa aatgttatac ttgcgccggt tttgtttatt acctccatga
    22501 tttctggtgg atgggaagaa acaaaaaata atatgattgc tgtttggaat aatattaaag
    22561 aaagtgccat aaatatttgg gaatctataa agaatatatt tgtaagttat tttacaaata
    22621 tttattttgc tgcactcaat atttggacag ggttcaagct tacattgata aatatttgga
    22681 atgaagtggt aaatcaagct aaatcgattt ggttaaacat aaagtatttt tttattaatc
    22741 tttggattga tataaaatat tttgcaattc agaaatggat tgaattgaag ttttctatta
    22801 ttcaaacttg gatcgattta aaatataatg ccattactac ttggaataat attaaacagt
    22861 ttttcaaaga tacttggaaa aatattaaag atacggcata caatacgtgg atttctataa
    22921 aaaataccat gattaataca tggaataaca ttaaggactc tttctggaat attgttactg
    22981 gaattgttaa ttctgctgaa aatgcatgga caaatctaaa aaatggtgtt tcaaatgcta
    23041 ttaatcgggt aaaagaaatc tttaattcgt taagggaagt caatttattt gaaattggca
    23101 agaacatcat tgatggactt ataaatggtg taaaagaaaa gtggaatgct ttgaaagata
    23161 ctatcaaagg tattgcaggt aatatcaaaa attggattaa aggagcttta gatattcatt
    23221 ctccatcaag atggatgcgt gatatggttg gtaaaaatat tgttcaaggt attatcgttg
    23281 gtattgataa agagcaaagt aagttagatc aaaccatgac aaatttagta aaaacaccgt
    23341 ctgttcaacc tgtagtaaat ggaataagtc acctaccaat tacacaaaca aagcaaaata
    23401 tatctgctag tgaaacaaaa gaaattcatt tacatttaaa tgtttatgga gatttacctg
    23461 attcaatggt tcggaagatt accacaaaaa ttaaaacaga attgacaaga caaatgaaac
    23521 gagatgctgg tgcagtagga ggaacattat atgcaactta agagaggaca attttttatt
    23581 aatcaacatt attcttctga atttaatgtg tatattcaaa acaggcctgc ttctgtttca
    23641 gctagtcgag taattgaatt gagagagcga gaaggaaatg attctatcat tattgataaa
    23701 ggctattaca gaaatgtgac tagaaagatt gagtgttact ataaagcacc ttcaattgat
    23761 gtggtgcagg agtgggaaga tcgaatcact gaatggttag atatgtcgtc ttatagtgat
    23821 tttattcttt actatgatga acaatatatt tatcaagctg tagtaataga aggacctgaa
    23881 tttaaaggaa caagaaaaac aggaaatatt gtcccttttg aatttacagt gagcattcga
    23941 ccatttaagg aaaattacaa tggtagattt actattcgac aaacagaaac ttttgaaatt
    24001 tataacccag agaagtattc ttcaaaaccg cttattaaat tgagtggttc tggagatgct
    24061 tctttttata ttaataagga caaatatgat ttgaaatcgt tggacagaga attatttata
    24121 gattctaaat tagaagaggc ttaccgaaaa ttagatggta atttagaaca tcaggatcaa
    24181 gtcactttat ttttagattt tccattttta tatcctggaa aaaatgaaat taaatggacg
    24241 aaaaatattc attcatttga aataatgcct aggtggtgga gaaaagtatg aaaccaagaa
    24301 tatatagtcc tactgaaaca gatttctcaa cgaatggctt aggaatttta aaggattgta
    24361 caagatgtga aatatatgaa gtagctaatg gaaaatatga attagagttg gattatcctt
    24421 taggaactag atttgatgaa tattttgaaa atgactatca aataaaagca aagccaaacg
    24481 atcaagaaga gtatcatatc ttttttattg atgataaaga tatagatact tttttaaata
    24541 cagtaactat ttatgctcag agtcgtacaa atcgacttgg aagacgggta gtcactcttg
    24601 cggaagtaga ctctaaaact ggtcaagaag cgatatcaat tattgaaacc aaaatggata
    24661 aaaaatctga catacgactt tattctgata ttacggccgt ttctagcaca atctttgaag
    24721 cgagaaatgt tttaaattgt attgctggtg aacaaggatc attgcttcaa tattggggtg
    24781 gagaaattaa acgtgaacca tttaagcttt ctttgttaaa gcgaagaggt cgcaataatg
    24841 ttggaacgat tcggtatgga aaagatatgt ctggtttaaa ggtcaaatta gattggacag
    24901 gtataaaaac aagacttatt ccatatgctg atcctcaaag tgaggtaggt acgactaatc
    24961 gaatttatgg ttcgccagta gatagtgcct atattaataa ctatcctgat gtgtatacag
    25021 agcatgttca gtttacagaa gaacaaggag taaaagacat taagagctta aataaaatag
    25081 ctaaaaatta ctttaaaacg atcaatcctg gctgtgataa gcctaaagtt tctattacgg
    25141 ttgaatttga taagttgact gatagtgaag aagcgaaaga atttgcgaag attagaaatt
    25201 atggtctgtt tgatacattt aaaatatatc ataaaaaata taatatttat cttgaatcaa
    25261 aggttagtgg actacaatac gattctttat ctgaaaaaac tttgaaatta gaagcaggag
    25321 acattcaagt tgctttttat cagcaacaag ctgtaactat tcaggataaa ttaaaagatt
    25381 atgcaacgaa taattatatg agtgatttta atgattatgt ttcttcaatg attacaggtc
    25441 aaggcagtgc aggaggatat gtaagtttat ggccaaaaga aaaaccttcc aacatcttta
    25501 ttatggataa tccagattta gaaaaggcaa gagaagtact aagaatgaat aaaaatggga
    25561 ttgctttttc taagaaagga tggcgggggc cttttacttc agcttggaca ttagatagta
    25621 tatttaatgc caattttata caaactggat taatcaaagc agatatcttt caaaattctt
    25681 ttaacaagac tggagatgta ttgaaattag ttaatggact actccaaatt tggaacaaca
    25741 aaaagaaaat aatggagtta actaaaaaag gaatggaatt ttggaattct aagggttcaa
    25801 ttggaacgat tggaacaact gattctgctg gtaatccttt tcctggggct tctactccaa
    25861 cccctattga agataattct ttagttattc gtacaaatgg agacggcaaa tatattttga
    25921 tttctcctaa agtaggaaaa ggattagttt tattaggaaa tggtaaagca atttattttg
    25981 gagacttaga tgtacaagga aaacttacag ttaaaggaaa agaaataatt cctggacaag
    26041 gtggtggtcc atcgggaggt ggagaatcta ctggtgggta tcctagtgaa ttaaaaacag
    26101 atgcagaaaa gagagcttgg agaat
//
LOCUS       DAFBSV010000036        25767 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.037, whole genome shotgun sequence.
ACCESSION   DAFBSV010000036 DAFBSV010000000
VERSION     DAFBSV010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25767
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.037"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(20..1186)
                     /locus_tag="LLB18_001386"
     CDS             complement(20..1186)
                     /locus_tag="LLB18_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBK5244396.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(1198..1551)
                     /locus_tag="LLB18_001387"
     CDS             complement(1198..1551)
                     /locus_tag="LLB18_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBK5244397.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            1679..2701
                     /locus_tag="LLB18_001388"
     CDS             1679..2701
                     /locus_tag="LLB18_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HBK5244398.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            2720..2881
                     /locus_tag="LLB18_001389"
     CDS             2720..2881
                     /locus_tag="LLB18_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244399.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(3140..3574)
                     /locus_tag="LLB18_001390"
     CDS             complement(3140..3574)
                     /locus_tag="LLB18_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244400.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(3684..5543)
                     /locus_tag="LLB18_001391"
     CDS             complement(3684..5543)
                     /locus_tag="LLB18_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBK5244401.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(5661..6820)
                     /locus_tag="LLB18_001392"
                     /pseudo
     CDS             complement(5661..6820)
                     /locus_tag="LLB18_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
     gene            complement(7127..8551)
                     /gene="araA"
                     /locus_tag="LLB18_001393"
     CDS             complement(7127..8551)
                     /gene="araA"
                     /locus_tag="LLB18_001393"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HBK5244402.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(8567..9265)
                     /locus_tag="LLB18_001394"
     CDS             complement(8567..9265)
                     /locus_tag="LLB18_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBK5244403.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(9222..10883)
                     /locus_tag="LLB18_001395"
     CDS             complement(9222..10883)
                     /locus_tag="LLB18_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HBK5244404.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            11101..12501
                     /locus_tag="LLB18_001396"
     CDS             11101..12501
                     /locus_tag="LLB18_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HBK5244405.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(12753..13832)
                     /locus_tag="LLB18_001397"
     CDS             complement(12753..13832)
                     /locus_tag="LLB18_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK5244406.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(13918..14877)
                     /locus_tag="LLB18_001398"
     CDS             complement(13918..14877)
                     /locus_tag="LLB18_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBK5244407.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(14889..16400)
                     /locus_tag="LLB18_001399"
     CDS             complement(14889..16400)
                     /locus_tag="LLB18_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBK5244408.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(16422..16985)
                     /locus_tag="LLB18_001400"
     CDS             complement(16422..16985)
                     /locus_tag="LLB18_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBK5244409.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(16991..17854)
                     /locus_tag="LLB18_001401"
     CDS             complement(16991..17854)
                     /locus_tag="LLB18_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBK5244410.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(17868..18764)
                     /locus_tag="LLB18_001402"
     CDS             complement(17868..18764)
                     /locus_tag="LLB18_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK5244411.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(18939..20228)
                     /locus_tag="LLB18_001403"
     CDS             complement(18939..20228)
                     /locus_tag="LLB18_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK5244412.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(20200..21717)
                     /locus_tag="LLB18_001404"
     CDS             complement(20200..21717)
                     /locus_tag="LLB18_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBK5244413.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            21915..22805
                     /locus_tag="LLB18_001405"
     CDS             21915..22805
                     /locus_tag="LLB18_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HBK5244414.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(22878..23702)
                     /gene="nadE"
                     /locus_tag="LLB18_001406"
     CDS             complement(22878..23702)
                     /gene="nadE"
                     /locus_tag="LLB18_001406"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HBK5244415.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(23714..25186)
                     /locus_tag="LLB18_001407"
     CDS             complement(23714..25186)
                     /locus_tag="LLB18_001407"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBK5244416.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
BASE COUNT         7538 a         5430 c         4407 g         8392 t
ORIGIN      
        1 tcccatctgt ctctttttgt tattctttct gctttttcaa cggattttct tcataaagag
       61 aagagattgt tgtgtaccat tcaaaaacat gagtaatcac tactttagct gctgcataaa
      121 caggaatccc caagatcaca ccgatgattc cgaacaattt cccagaagtc agcagaacta
      181 ataaaatcgt tactggatgg attgctaact gattccctag tactaatgga gagatcaagc
      241 gtccttctat tgtctgctct actgcaaaaa cgatcagtac tttgatgatc atgaatggac
      301 ctgctacaat ggctaaaaag atagccggaa tcatcgctaa aaatgatcct aagtaaggga
      361 tcaggtttaa aaaacccgca ataatcccca acgtgacagc atactctaaa ccaatgaccg
      421 caaaaccaat cataaacatg attgccacag caaaagccac agttagttgt cctcttatat
      481 aagaagaaac ttgactattc atttcactca gcacattcaa cgtcggtttt tgcatgcgtg
      541 tcggtaaaaa tttgacaaaa taaggtgcta attgtttacc gtctttcaat agataaaata
      601 agataaacgg catcgtcagc agagccacta aaatagtcgc taccgcgccg acaaaacttc
      661 caagactctg aactgtactc ttagatatat cttggatcat atcgcctgcc gaattcatga
      721 acttatcacc tgctgtttcc aactgttcgc gaaattggtt gaacagcggg tcccgcaaaa
      781 tctcggttaa tttattatca atcgtatcta catattgagg gaagttactg atgaagctca
      841 ctgtttgttc ctgaatctta gggatgatca ctacgctccc ccatgcgatt agtgcaacaa
      901 ccaaaacaaa cagcccaatg atactgtaaa gccttggtac ttttcgcttt tcaaagtaat
      961 caactaccgg attcatcaag taatacaaga ttcctgctaa aatgataggc agacctacga
     1021 ttgctaaaaa ttgccagatt ggtgcaaaca aatatgaaac ttttgtaaat aaaaagacga
     1081 tcagcaatat taacaataca acaagtaagg ctgtgactac ttgattattt aaaaaccagc
     1141 gccaaaacca cgataccggt ctgttcttct tattttttcc ttccataatt cctcctgtta
     1201 gttataaaaa atttggcttc ccaaaccaat agcaggcagt ctatgcggat gaagatagat
     1261 tccatttgca atttgtcctt cttctggaca agcatcaaaa atcaatgata cgtgagctac
     1321 tgtctttaaa ttcccattgg ccatcggacc gacataatcg atcgtatata cctgatcatc
     1381 aaaagcaatt gttccgcctg ctttcaaaga aaaaggttcg tcttttgata cttcttgaat
     1441 caccgaatat tttcgtaagg cagctgttgc tgttttatcg aacaaaatca gcatgggttc
     1501 ttccttgttt attgcttctg tcccaatttc tgtaatcttt gcctgaatca ttgcactctc
     1561 tcctttaatt gctttcaaaa acagtataac acattctcat tctttagccg tgtggaataa
     1621 ttatgtgata gaataaaaac gaaaactatt tcattacaat taggaggaat cagctcatat
     1681 gatcgaaaag ataattttag gaacctatac gcgtcgcgaa agtaaaggaa tctatacgat
     1741 cgaccttgat acagaaaaag aagaattagc caacctttca ttagctgttg aagaaaatag
     1801 ccctacctat gtagcaaaaa gtaaagctgg caatctttac acagttacta gtgtggatgg
     1861 attaggtggt gccggtgcgt acgataagga ttttcatttt ttgaatgcgg taacagagtc
     1921 tggcgctcct ttgtgttatg tagcggttga tgaagcacgt caattactat acggggcgaa
     1981 ctatcataaa ggtgaagtaa atgtctacca tatattagga gatggcgaac tgaaagcagc
     2041 agattcaata ttccatcaag aagcgacagg tcctcataaa aaccaagatc atgcgcatgt
     2101 ccactatacg gatctgactc ctgaccaacg attagtcgta tgtgatcttg gtacagatcg
     2161 tgtgtatact tatgatgtgt ccgaaaacgg caaattgaat cttgtaacta ccttcactgc
     2221 agagccagga acaggccctc gccatcttgt ctttcatcca aatggacaat tcgcttattt
     2281 atttggtgaa ttagacagca cagtccgcgt gctttcttat aataaagaaa caggtgcttt
     2341 tgaagaatta cagaaaatat cgaccttgcc agaagaattc gacggtgaaa atggaggggc
     2401 agctatccgc atttcaaatg atggcaagtt cctttatgct tctaaccgag gacataactc
     2461 gattgctgta ttcgcagttt ttgaagatgg ttcccacatt caaaacaagc aaatcatctc
     2521 aacagaaggg gattttcccc gcgatttcgc actagatcca agcaataatt ttgtcgtgtg
     2581 tgccaatcag aacaccgata atctgacatt atatcgccgt catcctgaaa caggattact
     2641 ggaattactg aaaaaagatg tctatgtacc agaatgtgtc tgtgtttatt ttgatcgtta
     2701 gtaagaaaag gagaatgaaa tgaatcagca agacgtatta gacagactac gggaagaact
     2761 aaatattcct ttctttgatg ggaaaatcga agataaagag tatagcgaag aggaatatca
     2821 gaaactcaaa gccgatttac agaactactt tgaacaatat gtacagaatg tagaaaacta
     2881 atcagctttc catactatct gaaaagaaca tcaggacaag acttttccgt ctatcctgat
     2941 gttcttttct acaaataaaa aaccgccgag atggttagac tcgacggaaa aggagtattt
     3001 actcgatttt gagtaagtac aaggttgttg ttggttatag gtatgtcatt atcataaagg
     3061 attttgatca ctctatcata aaggtaatat tacatttata ttagataact ctagttttta
     3121 ttgttatcaa agatttcttt tattttttca acaacaaatt agtcattttt tggatggcag
     3181 ctgtcaattg gtctgtcgct tggtcttgtt ttgcttcaga tgtattgaat agatcttcat
     3241 ctacccctga ttcaagatcg atactttgga tcatttcttc acagcctgct acatatgaaa
     3301 gataagcttt ttcaaaattt ttatgaatgc ccattgcttt tgctggtgga cgcaaagtac
     3361 tgactttcat aagcattgcc cgatattttt ttgttccttc ttcaaataac aggatgatct
     3421 cttcaagagt cgatttgtcc agttcacttg tttttccttc atcaattgcg tttctgatca
     3481 cttcatattt cggatgcatt ccttctccga ttgcttctgt ttccttgacg atttgatcga
     3541 tggactgcac ataatagcca atattcggta acatgttcgt tttcctactt tctccattgt
     3601 tgttattatt tattctactt gtttttatcc tcaaatgaca agtacttgaa aaaatttaat
     3661 ggtttctata cagctcgcca ttcttattcg tgctcaaaga aaccatctgc taaactatat
     3721 tgtttccctg cgacaatgtc atattggatc aattgatatt cgtcgtaaat ctcttgttgc
     3781 gagcgattga attgcgcttc tttataccac tgtccgtttt gatagtacag ttctcgttca
     3841 aacgccggaa gttcctgttc taatgataaa agcagctgat aaaagccatt tgttgtctga
     3901 ttcgtctgtt ccattagatt cgctgcaaaa taaaacggac tggtgattgc atcgtgagtc
     3961 gtttgctttt ctaattctcc tttactgtcg aacataagaa attgtgtttc atgcaatgtt
     4021 tgtttgtcat tttttgcttg gatcgtatct gaatagatcc ctggaagatg atccccccaa
     4081 aaaacaacta aagtccttct agaaagattc ttcaattctt ccgtgaactg cttcagtgcc
     4141 gtgctgctat aggaaatatc ttgcagataa ttctctaagt caagtgtccc acttccatct
     4201 gaagtttttg caggatagtc tagattatca tactttccat cgtagggcat atgtgtctgc
     4261 atcgtgacta aatgaatgaa ctgaggtgtt ttttcttcct tgagaagtgt cattacttct
     4321 ttgtaagctg actcatcaga aatatatgga ttattctcta tcgtatccgt ataggtcatc
     4381 gtacgctcgc tgatgaactg gtcaaatcct aatgtctgat aaacatcctc tcttttatac
     4441 atcgaagtat tgtatggatg gatcgctgtc gtctggtatg attgtgcgtt taacgctgaa
     4501 acgatagaag gaagctgatc catttttggt acaagcatcg tgtaaggggt ggtgagttgc
     4561 gcattaaata acgccataga aaaaccagtc aatgcttcaa attcgatatt tgctgttcca
     4621 ccgccatagt tttgagaaag catattgcca ctatatgttt gatcagctac ttcataataa
     4681 tctgccaatg gctcaccaga tacttctacg ccgtttaatc gactaggatc tgagaaactt
     4741 tcactcatca cgaacacgat gttcggcgac tcttcctcta cagttttatt tttttcatcg
     4801 gctagcttct ggtatttttc agtgatttct ttgatctttt ctttcgaata tccttcaggt
     4861 tcatccattg gttctacctt cagattgtac aaaaacccac cgataaaacc agtgttatag
     4921 tagttcattt tctggctgta aggtatccat agtgccgttt tattatatgc ttttcgcaac
     4981 aaattatcgg gattgttgaa attactgata taccctagca gtccaattgc cacaagcagt
     5041 gtcgttaatc ggatcaattg gaatcgcctt ccttttttca ggcttcgaaa catgtaccag
     5101 caaaacaatc ctatcacggt tcctgcggca gctaagatca ctgtaaacag catagtgccg
     5161 gtcatatctt tcagcaatcc gatttcagtg atcatcttca aatcgtctgg ataaatcggt
     5221 tcttgccgat aactcatttt catataattt gcaaaaccta atacaccgat ggctacgaca
     5281 tacgtaaggg aacctaaagg gacagatcct gctagtgcaa tcagaaaaat aagaataatc
     5341 agcaagacga gacaggctaa gaagaatttt tccgtatgcc aagaaaaagc aaatttcaac
     5401 gcaaggtcta cggatagatc attttgacac cactgcaaaa ataaattact aaaaacaaca
     5461 agaaaaaaga tactgatgat tgctgctgtt ccttttaaaa tctttttctg tttggtcgaa
     5521 agtctgctta tatatctttt caaatgcttg ctccttcatt tctatcaata aaagaatgtt
     5581 gcttctctta ttttagttgt acgaaattcg aaagtaaaga acggaaagaa gaattaatga
     5641 aatccaaata ttctctttct ttatggcctt tctggtttct ttaataagcg gacctttcgt
     5701 actccagaaa ttttttctag ctgttgtttc acttgattga gctgttcaaa atcagtactg
     5761 tctatgtcaa tcaatatgta gacatgctca ttcttatggt tacgcgatat atctgcgatc
     5821 gctagctcgt tctcattcag cagagaaaat atctctgcta atatattggt tttcttttga
     5881 taaaatatag tgaatcgaaa cggcgcttgg aaaaacattc gtgcggatgg ataattgacc
     5941 gcttctctaa ccgtaccgaa caaaagataa tcttttaagg cttcaactgc caaacgtccg
     6001 ctgtctgcca aagcttcctg agtcgatccc ctagatgagg caacataagt atacggtcat
     6061 tttctaagaa ctcttcttct ggaaaatcag tcaagtattt agccagatgt tgtttttcca
     6121 atgcttgcat aacagcatat ttatcaacaa tttcacttct tcctacattg ataagtacag
     6181 catctttttt cattttttct atattcgcct gatcgatcaa tccttttgta tcttctgtca
     6241 acggcagcat gactacgatg taatccgagg tagaaagaac tgtttctaaa tctgcttgcc
     6301 gaacataatc caactgggca tcgcggatag aataacccaa gacatccatc cctaagctat
     6361 agcaacttag cgctactttt gtgcctatcg ctccaagacc aagaagaccg atggttttgc
     6421 cttgcaattc tcgtcccaca taagcacttc ttttgttttc tgcctgttct aaaatattag
     6481 gacctgttag tgtttgtacc atacgacttg cttcgattat cggacgggaa gataagagca
     6541 aacagcacaa aacaagctct tttactgcat tagcatttac acctggtgta ttcatgacga
     6601 tcgtcccgtt ttcagaagct ttttcaacgt tgatcgtgtt caccccaaca ccagctcttg
     6661 aaattgctag caaatctggt gtaagccatt catctttcac tttcgtacta cgaataacta
     6721 ttccttcggc tggcaaatca tctattattt tgaaatattc cccttgtaac ttttctatct
     6781 cttgttctgg aatagcatca atcaaatgaa cgtgatacat aaaaccccct ccttactaac
     6841 aagtatctcg aaatttctgc aattagacaa ctgtttacca tttgacttcc tagaagcaaa
     6901 aagagcagtt agagcagagt aggctgagtg ataaaaataa ggctatgaca agttactgcc
     6961 ataagcctta ttttcgagag caaaatattg agggtgagat atcttgataa atggtgttcc
     7021 gttagctgac attgataata agactaaatt tcaaaaaagt tgaaaagcaa atttcgtcaa
     7081 tctcttctta tttcttaaaa ctaagtggct ttttcacaac ctctttttat ctaataacca
     7141 ctgtttccaa ctcaactaat tttgcccacg tttcaatttg atctgttgtt agatttagcg
     7201 agacaacggt atgatgaccg ccacctgcct gaatccatga atggacacct tcatggaaat
     7261 tcggtttagt tttccataac acacgtgcaa caggtaaatt aggtgcttca gtcgttggtt
     7321 caaaggcttc tacttcattg atcagcagtt tataatgcgt accgaaatct gccatcgata
     7381 cgactacccc ttctcctgct ttcccatcaa atacaagacg cgccggatct tctctatctc
     7441 ccattgataa aggagaaaca acgattcttg gtttcgtcgc agcaagcgtc ggatctactt
     7501 ccatcatatg ggattccaag attgcttctt ggccactagc tagctcgtaa gtataatctt
     7561 ccatgaatcc tgtatctttc cctcgagcca tgattttcag caaccgatca atcgctgcag
     7621 ttttccagtc gccttcccca gcaaaaccgt atccttctgc catcaaacgt tgtacagcta
     7681 gtccaggtag ttgtttcatt ccatacaggt cttcaaaatt agtcgtaaaa gcgttatagc
     7741 ctccttcttc taagaaacgg cgaataccga tttcctgctg agcttgtact tttacatgtt
     7801 cctcccatgt cttttcttca taatcaccat agtcgaaggt atacaattcc ttgtactctt
     7861 caaataattg atcgacttct tcgtctgata cgcgatcgat tacttgtaca agatctccga
     7921 taccaaaata atcaacagtc caaccaaatt gaatctgtgc ttccactttg tctccttctg
     7981 tgacacccac gtttctcatg ttgtcaccaa aacgagccac ttttattcca aaactttcat
     8041 tataggctac tgcaacatcc atccaatcag caatctcttt ttggatctca ggtcgtttcc
     8101 agtagccaac gacgatttta ttttgtttat ttaatcgagc attgatgaac ccatattcgc
     8161 ggtcaccatg agcggattga tttaaattca tgaaatccat atcgatcgtt ttccaaggaa
     8221 tgctttcgtt atattgcgta gctaaatgaa gcaatggttt ttgtagaagc tttgtcccgc
     8281 ggatccacat ttttgctggt gagaaagtat gcatccaagt gatcacacct gctacttctt
     8341 ctcgataatt gacctctttc atgatttttg tgatcgtatc agcagtaact gctaattctt
     8401 gaaggcggat tggataaggc aattggccat tttcattcag ttcatcgacc atttcttgtg
     8461 catgtttctt tacttctcgc agtgcttctt ccccatataa atgctgtgat cctacaacaa
     8521 accaaaattc tttttctcca atattcaaca taattagcca ctccttttat ttgttttgtc
     8581 cgtaatacgc attttttccg tgttttcgta aataatgttt atctaaaatc cgttgaggca
     8641 gctcttctga aaatgaattg agctgtctgg taaataaatt catcttgcat acttcatcta
     8701 gtacgactgc gttcattacc gcactttgcg catctttccc ccaagtaaat ggaccgtgtc
     8761 cgtgtaaaag tacccctgga attgctaagg gatcaatttt gcgttctttg aatgtttcta
     8821 tgataacttt tcctgtttca tattcgtacc cgctgtcgat ttcctgttgt gtcaaaaatc
     8881 gagcacaagg taccgatcca taaaaagtat ctgcatgcgt cgtccccatc gcaggaacat
     8941 ccaatcctgc ttgtgcccag atcgtcgccc atgtcgagtg agtatggacg attcctccga
     9001 tttgaggaaa tgaacgatat aaaacagcat gagtaggcgt atccgaagag ggattgagtt
     9061 taccttcaat gatatgattg tccaagtcca caacgaccat gtcgtctgct gtcatctctt
     9121 cataactgac tccgctaggt ttgataacga aatatcgtgt ttcaggatca aaagcgctca
     9181 catttcccca tgtatatttg acgagtccgt gtttaggcaa gtcaagattt gcttggtata
     9241 cttcttcttt cagttgttcc agcattttct atcactcctt tttcttgcaa ttgatgaatc
     9301 gctgtttttt caatgtcgat cccctcacgg taacgtctca taaatatctg atagcctgct
     9361 atttcttctg ctgaaggtgt gatggtgatt ccttggtctt gtccaaacac gtcttctgcc
     9421 aagaagtttt ctaaagactt cccatgtcga tccatcatat aggctgctaa taacgcgatt
     9481 ccccacgctc caccttctcc ggctgtgtcc atcactgtaa ctggtgcctc catagcagat
     9541 gctagaatcc gctgtccaac ttctggtgtt ttaaaaatcc ccccatgccc cactaaacga
     9601 tcaatttgga cattctcaga tttcaatata tccattccga ttctcattgc accaaaagca
     9661 ctggctaaat ggatccgcat gaaattcgct aaatcaaaac ggctacctgg tgtacgtaca
     9721 aataatggcc ttccttcatt tactcctgta atgttttcac cggaaaaata accataagaa
     9781 agtaatcccc cgcaatccgt atcgccttct agcgctttgt tgaataatac cgtgaataat
     9841 ttatctctgc ttatctccat acccaaagaa ttggtaaatt cttcaaaaat actgacccaa
     9901 gcattgatat ccgaagagca gttattcgta tgaaccatgc ctactagttc tcctgaaggt
     9961 gtagtgacca tgtcgatttc cggatggaca ttttctagtt ctttttctaa tacgatcata
    10021 gcgaaggcgg aagtaccagc cgaaatgttc cctgtccctt tggctacact gttcgtagcg
    10081 accataccgg ttcctgcatc cccttctggc ggacaaaccg ggattcctgg tctcaaattt
    10141 cccgtagggt cgatcagata agcccctgat tcgcttaact tgccagcttc ttctcctgct
    10201 actagaactt taggcaaaat gtgatccaag tcaatcgcta cgtgcgcttt ttcgattaac
    10261 tgaccaaaaa tatttttcat ttcttgatgg taggttttcg ttgaaggatc gataggaaac
    10321 atgcctgatg catctcctac gcctagtact ttctcaccag taagctgcca atggacataa
    10381 cctgcaagcg ttgtcaaaaa attaatttct ttcacatgtt cttctttatt caaaatagat
    10441 tgatacaaat gagcgatact ccatctctgc ggaatattgt attgaaattt ttccgttaat
    10501 attcgttctg cttcttcagt gattgtattt cgccaagtac gaaatggtac tagtaactgt
    10561 tccttgctat caaatgctag ataaccgtgc atcattgcac tgaacccaat cgacccgatt
    10621 gtcgtaagat tctcgccata gatttcgaat acttctgctg ccatttttcg gtaactgacg
    10681 cgcagtcctt tccaaatatc ttctaatgaa taggtccaga taccattttc tagtttgttt
    10741 tcccactcat aactaccagc ggcaatagga gtaaaagatg aatcaatcaa tacagctttg
    10801 atcctagttg atccaaactc aatccctaaa gatgtacgac catctatgac atctaacata
    10861 ctttgcgcat ttacttcctt cataatgatt taactccctc cttctcgtca aacctgatca
    10921 aaccgtcttt ttagtagcgc ttacaatgat tattgtatac ttttgtacgt acatgtcaag
    10981 cagttattta caagaataca ataaaaaaca cttgttttgt acgtacataa gttataaaat
    11041 gaaattgctt acaaaatctg atcaaccgcc ttctcgaaat tctagaagga gagaatactt
    11101 atgaaaaaag aaaaaaaagt ttcctcatcg tttatttatt tttttggcgc atttggcggc
    11161 attctatttg gatatgatat tggtgttatg accggcgcct tacctttttt acagcatgat
    11221 tggggtttgg caggtaaagc ttctttgata ggatggatca cgtcttcggt catgttaggt
    11281 gcgatccttg gcggctcttt atctggtctt ctttctgata agcttggacg acgaaaaatg
    11341 attcttcttt ctgcacttat ttttatggct ggttctgtcc tttctgcatc tgcccctcac
    11401 aatggttctt attttctgat tgcagcaagg attcttctag gtttagctgt tggcgctgca
    11461 tctgccctag ttcctgctta tatgtctgaa atggctcctg ctagactaag gggaagattg
    11521 tcagggatca atcaagtgat gattgcttct ggcatgctcc tttcctatgt tgcagattat
    11581 ttgctaaaag ggttgcctga aacgatggct tggcgcgtga tgttagggct cgctgctgtc
    11641 cccgcgctga ttttattttt cggtgtttta gctctaccag agtcaccgcg ttttcttatg
    11701 caatctggcc gcttggaaga ggcaaaaaga gtattgaact atattcggac accaaaagaa
    11761 gctgaacagg aattcgaaca aatccagctg aatgtcaaac aagaaaagac aaccggaact
    11821 tcttggcata ctttgttttt agaaaaatat cgttccttag tcattgccgg tattggtgta
    11881 gcagtattcc agcaatttca aggagctaat gctatttttt actatattcc gctgatcgta
    11941 gaaaaagcga ctgggcatgc agcgagcgat gcattgatgt ggccgatcat ccaaggaatc
    12001 attttagttg ctggttcttt gctctttttg gttattgcag acaagttcaa tcggcgaact
    12061 ttattgaaaa taggcggtag cgtgatggga ctttctttca tcctaccagc tgttttagga
    12121 actgtactgg atgctcatac aaattcgttg ttgattctct tgtttttatg tatttatgtc
    12181 gcattttatt cttgcacatg ggctccactg acatgggtaa tcgtaggcga aatattccca
    12241 ctagctgtcc gcgggcgagc atctggccta gcctcttctt ttaattggat tggttctttc
    12301 ctagttggct tgctttttcc tgtgatgact gcttctatgt ctcaagaaat cgttttcggc
    12361 atttttggga tcatctgctt tttaggggtt ttatttattc aagagatcgt accagaaact
    12421 cgtgggaaat ctttagagga aatcgaacaa agtgcatcta aaaaaactta tcctaaacgt
    12481 atttctatcc atcattctta aagaggttgt gacagaagtg gtcagcttca agaaataaga
    12541 aggaaccgct tagtttccag tcacaaggaa caatttcaaa aaacagcttc tcatgtttga
    12601 tgaatattgt gacttgtgac cagttggtag gagaacaccg tttagtggag aggtggtgaa
    12661 agaaacgttc agccttgagc gatgacaaaa gctctcacaa acattgcgac gagtaaccgt
    12721 aggagcaata agaggcggta aaaacccgtc tcttattttt cgttttcttt cactgtttcc
    12781 cgttcaacta gtacaggttc atagagaata tttggctgtg cctgtccttt ttcaatcgtt
    12841 gtgacgatcc accgtgcggc atcttgtccc aacttttctt ttggatgcgt caatgttgtc
    12901 aattttttat tccctaaatg gcttaaagaa gaatcgtctg ttcctacgat cgataggtca
    12961 tctggaatat gatagccatt ttctgtcaac ttatctagca ttaaactagc tatttgatcg
    13021 ttatagcaaa tgatgccatc taaagcttgt tcttctttca accgttgtac tgttttttca
    13081 gcgattgttt ctcgtgtttc cgtggtgaaa gtaatgatat cttccgtcaa aaaacgcaca
    13141 ttatactgtt cacacgcgct gataaaacct ttcatcctgt attttccttg aagatcgtcg
    13201 atttttgtga tgaacaacag acgctgatgt ccttttttta tcaaatattc tgctgccata
    13261 aaaccgactt tcacatcatc taaacaaata taagaggcat ttaactcttc ataagcagca
    13321 ttgatcatca ccatcggaat gccttgttct ctcaaagcaa cataaagtgc taagtttggg
    13381 ttatactgat tacttttcgt aggctcaacg atcaaaccat ctaccccata agcaatcatt
    13441 ttcttcaaac actctttctc caattcgtga tcgttattcg tactggctaa aagcaatgaa
    13501 tacccagatt ctcgtaattc attttcgatt cctcggataa tcgacggaaa aatataatca
    13561 gagagatatg tggtgatgac accgatcgtt tttgttctgt tcaatggtgt tttttctttc
    13621 ttatagctgt catctacata tgtgcccgac cctttttctt tacgcagata gccctcattt
    13681 accaacacag cgattgcttg ccgaatcgta tgtctgctga cgtcatatat ttcttgcagc
    13741 ttgaattctg agggaatggt tgtatttact tcgtattcct cacgaaggat cttttgtttt
    13801 atctcttctg caatatcttg atattttgcc atttgccttg ccccttttta tttgtacgta
    13861 catatatcat aacgagtctg caaggtttat tcaagcaaaa atcaaggttt cttgtgctca
    13921 taaggcatac ggaacaggtt caccaaattc tggaaatcct tgctcattcc acgtaaagca
    13981 ttgcgcgttc gcgtgccgat taggattgtc taacggatcc cctttttggt tcttctctgg
    14041 tcgagcatga tagatcaaaa tatcaaagca cccgtcttct gaaaccgtaa acgagttgtg
    14101 accaggacca aattgcttat ttttttcaga agaaacgaat actggctccg ataatttatg
    14161 ccatgattct tttaataaaa gattcttgtg ctcatcagcc cacagcaggc ccatggcata
    14221 gttttcatct gttgcactac cagaatacgt aatgaatatt ttcccattgc gagtaaggac
    14281 tgctggacct tcatttactg aaaaaccccg tttttcccat tcatactcag gtatagaaag
    14341 gaggatctgc ttccccttta acgtccaagg attatccatt tcggatagat aaagattaga
    14401 attcccagta atttcaggat cttgttgggc ccacacataa tatagctttc cttgagaaga
    14461 gaaagttgtt ccgtctaaac tgaaagtttc ccttttcgtt tttatttgtc ccttttctat
    14521 ccaatctgta ttcattggat ctatatgctg attttcaagt acgaacatgc ggtgatgatg
    14581 agattcatca cgtatagttt tatgattgct tgcagcaaag taaatatacc attttccatt
    14641 gatataatgg acttcaggtg cccagatcaa ttcactcatc ggtccttctt catgagcctg
    14701 ccatacaatc aggcttgcag catgttctaa ttcattcagt gactttgccc ttcttaattc
    14761 aatcacttgg tagcctggaa ccgatcctgt aaaataataa taaccatctg tatgtttata
    14821 tacccaagga tctgcccgtt gccgaacgat aggattatta taaagtgtct tcatcataac
    14881 aaatttcctc acattttctt tattctaatt acattccaag agtatttttc tatccctaca
    14941 tttaattcgt catgtttttc tattgaaaaa tagtttattt caggttttat tttttctggt
    15001 tcttcacgtg tatttttgtc caacagatcg ctactggtta atgtgtagtg ctctccttga
    15061 tctagcaaat tgaaatcatg ttcaatcgtt atcttttgtt gttcatttgt gcgattgatc
    15121 aagaaaatag tcagctgatt gccgttatct acgatcacac tgtccacata aggaacattt
    15181 tttatctttt cacaatcata aacagggcaa atgatttgtt gtttcaatac ttgaccttta
    15241 gcatatttcg ataagtgttg catcacataa taagttggat tcctccatgc ttgtccttta
    15301 gcatctgtca gtattaaagg tattgtgttt actaacaatg attgacaact aatctttacg
    15361 cgatctgcgt gtcgtaaaat agccagccct aatgaaccaa ataataatgt atcttccata
    15421 gtaaagtaac accaatcgat gggactaccg acttcaaaat ccctatgtct tttttccggt
    15481 tgggcatgta cattccattc atcaaacgct agatacattg ttttctcact tctcaaatat
    15541 ccttttacat aatcacaagt agcaacgatt tcttcaattt gacgatcgaa tcgataagct
    15601 tttgcaaggt atgtcgctgt atcatcacgc tcatttttag gaggtttagt caagtcttct
    15661 tcatcatact tatcaatata gttatgcaaa gctaaataat ctacattctc ataagcttct
    15721 tctaatgcga tacgatccca ttcagggtac gatggtaaac gtggcgtaga gcttccaact
    15781 aagattgttt caattgaatc atccactaac ttcatgactt ttgaggcttc atttgctaac
    15841 ctaccatatt cataagcact cttagccccc acttgccatg gaccgtctag ctcattccct
    15901 aaacaccata atttaacgcc aaaaggcttt ttttgcccat tttttattct taaatcactc
    15961 cagaaggttc cttttggaaa attacaatat tctactaaat tttttgcttc atcaattcct
    16021 tttgttccta aattcaccgt gaatatcggt ttcgcttgta catgactgat ccatttaaaa
    16081 aattcgtgga gtccaaaaga atttggttct atacctcgcc atgctaaatc aatttttttt
    16141 ggtcgttgtt ctttcctacc tacagtatcc acccaatcat aaccagatgt aaagtttcct
    16201 ccaggatagc gaatgacacc taattctaat tcctttacat aagagaggac atcttgtcta
    16261 aacccgtcac catcagctgt ttcatggccc ggttcataaa tccctgtata gacgacactt
    16321 cccatatgct caacaaatga gccaaacagc cgagaactga tctctcctac cgtaaaatcc
    16381 tctctgattt ttactttcac ttcttcgtcc aacagctttc cctacctttc atttcctata
    16441 gtcaagataa tagatacaag tttccatacg ccaccagcaa agataaaaat aaaaggaggg
    16501 aaaagaaata tgagcagtac aaatcctaat aacaatacgc aacaaagaat atttctcaaa
    16561 aaatcaaaaa atactttcca tgcactttgt tcaaaaattt gtaaaaatgt gatatctttg
    16621 ttttcagaaa tcacatatat ccaggataaa agaaacatgg aataaataag taaaactaca
    16681 tatccactaa ttgaaagtac gattgtctgt tcttctaata attgattaac aagaaaataa
    16741 ataatgatcg ttaacagact aaggaacaag ttcttaccaa aatgttgctt tattccttga
    16801 aagaaaaaat aaatgatatt tcctgatccc tcacctttcc attgcgccat tacataaaaa
    16861 acagcacatg tagcaggcac gatagtaata acaggcaaac acacgattac ccagagaata
    16921 cctaataaga tgtaatcaga aaccacaatc aactgtccat aaagtttagt ctcaactatt
    16981 ttcatcttcc tcactctttc attccagaca tagctgttcc ttgaacaaaa tatttctgtg
    17041 caaaaatata aaccactagt aatggcagca ttgaaataac cgttccagcc attacaggtc
    17101 cataaaaaga aatgttctgc cctgtaaata aagctaaccc tgctggtaaa gttctcattt
    17161 ttgaactact tgtcaatatc aatggataaa gcaagtcatt ccaactattc atcagcgtga
    17221 aaatccctaa tgataaaaga gtaggtttgc tcaatggcaa catgattttc aaaaaaatat
    17281 taaactcact taatccatca atgcgtgctg cctcttccaa agaatctggt aaagtaataa
    17341 aaaaggaacg catcatgaag ataccaaatg cagttgtcat acgaggaatg atcaaacctg
    17401 cataagtatc aagcatgcca agcaaattga cttcaataaa tagaggaatc atgaagactt
    17461 ggaatgggat catcattgtc agcaaaacga aatagaacaa aactgatttt cctttgaaac
    17521 gcatacgagc aaatgcatac cccgcaagag aatcaaagaa tacagaagtg atcactgtcc
    17581 ctccagcaaa aatcactgta tttttgatgt aatctaataa agggatcgtt gtccaaacct
    17641 taatatagtt atctagggta tagctatctg caaatattct aggcggaaat gagataatgt
    17701 ctttttcgtg tttaaaagaa gaaataatca gccacaaaaa aggaaacgca ataaccaaca
    17761 atataactag catactaatc gttcgaatga tttttttacc actaactgct tttcgactat
    17821 tcacagtaac tgtaatcgag ctttctggtg ccatacaggt ttccctccta tttcatttgt
    17881 ttttctttcc gtgacatgta cacattagtg gagatagcta tagttgcaac aatgataaac
    17941 aaaaccgaag acagtgctga tgcatagccc aattcataag gtgctgtaaa tcctcgactg
    18001 taaatatatt gaacagctgt ttctgtctta aattgtgggc caccagcggt tgcaacatat
    18061 acttggtcaa acacttgcat cgaaccaatc agattcgtta aaatacaaaa acctaaggag
    18121 ggaacgatct gaggtagcgt aatgttaaaa aactgctgtc gatttgttgc accatccatt
    18181 tgagcagatt catacaaaga gggagagatt ccctgaatag cagtcaagag aatcgtcata
    18241 gtaacaccaa aattcttcca aacagtcatg atggctaccg tcggcatagc aagggttgga
    18301 tcgcgaaaaa attgagggat cggcaagccg acttgtgaaa acaagtaagg aatcgcccct
    18361 acattcggat caagcaacat agaaaaaata atcgcaattg acgtcaatga acaaataact
    18421 ggaatgtaaa atgtcgaacg acaaaaacga ttgaatctgg tatttttaga taatgctact
    18481 gctgctaata aaccaacgat aatttgtgtt ggcgtttcga gtacggtgaa atataaagaa
    18541 tgaatcaacg aattaactgc tcgttcatca ctaaatatac gtgtgaaatt ttcaaaactt
    18601 acaaaatttc ttgatgtaaa gaaaatattc aaatctgtaa aactaatagc aaatgttcct
    18661 aaaagcggta tgacagtaaa taataataaa actaaaaaag atggagttaa aaacaaatac
    18721 gcagcacgat caggacgatt ccaatatttg gtgaatccgt tcatatagtc cacctcatct
    18781 ttcattttga taaaatatac aatcttggtt taaacgaatc tgaataagat atccgaacaa
    18841 tcgctgtgat ttttgcaata acacctatct gcaaatacta ggtcgatcat tcagatatct
    18901 gtatcttgcc aacagtctat cctgtataaa gttctgtact atttttgcag taattgattg
    18961 atggcatcat ctgcatcgtt catgagtgtc tcaggatctt ctcctgctaa taatttttca
    19021 atcagtggat tgatgatatc gttattgatc gcagagattt gggtaaaacc tggtaaatat
    19081 ggctctgcat agtccatttg tttcgataat tcagatacaa taggatcatt ttttacttct
    19141 tcatcttttg ctactgaatc caagtaggca ggaaaaccat tttcgatact ccatttttta
    19201 ccaatttcag ttgtattcca atatttcaaa aactcataga cagcttcttt tttattatta
    19261 tctgtacttg ccggaatggc atatcctacg ccatctaaaa tagctgtttt tttgtctgaa
    19321 tcactccctt gtggtaaggt agtcacatta taatcaatct cgtttgcttt caatccgtta
    19381 tttaaccatg gcccattgat ttcaatggct agttgaccag cattcattaa attgtccatt
    19441 tcggcgccag aaatcgattc tggaccagtc ttgtctacat ggatcatttt ttggatcgct
    19501 tttaacgttt taaggttctc aggagacgca aattcagact tagtataatc atcgttcact
    19561 aatttaccgc catttgctaa catccagtta tataacggtg cagttccatc cttattgaag
    19621 acaaaacctg atacattttt actactatca gttaattttg gtgccatttc tgtcaattct
    19681 tcccaagtag taggtggttg ttcagtatct aatccagctt gtttaaacaa atcattattc
    19741 caatacatat acatgccttg tacctgcatg gggacaaaat actgtttacc ttctacttca
    19801 cctaattcaa tagccgtttc tttaaaatca gatttatcta ctccatcata ttcccagaaa
    19861 tcgtctaatg gttgtaccgc tccgttttct acatactgtg caaaatctgg ataatttaat
    19921 gcaataaagt caggtgcttt tttagaagaa atcgctgtag gaagtttttc attcaaattg
    19981 gcccaagtca tgatatccat ttcaattttg atgtttttat catttgtttt attaaattca
    20041 ttaacgattt cttgcaatat ttcaccatca gatgcagtaa acccattcca aaaagtcaaa
    20101 gtcacttctt tatcagaatc agattctgct gaacttccgc caccgcaagc tcctaaaata
    20161 cctgttgcag ctaccaacaa agagccaatt aaccattttt tacctttcat tttttgttcc
    20221 tccttcatct gataaacgac atctgaccac attccaagat agcggtttca ataaacaatt
    20281 gattttccca tcttcagctt ttacatttgt tgaatgactt ggttttactt gttcactttt
    20341 aggaagatta gttgcttttg tatcaaatcc actcatttca gaaaaatcaa tcactccctc
    20401 taatgataat tcagacaagt gaacagttag attcatttct tcttctccac ggttaactgc
    20461 aaatatgaca agttctttgt catttattac ggctatactt tctaaatacg gcacttcttc
    20521 aaaatcttcc gtcgcatagt ttgctgaacg aatttgtggg cttaacacct ctccttgtcc
    20581 atacacagca gcttgcataa atggataata gatcgtctgt ctccaagctt ctccgtttgt
    20641 ttctgtcctg attggtgcaa taacatttac caattgagca agacaagcaa tctttactct
    20701 atctgcatgt ttcaataaag tgattaatag acagcctaat agtaatgcat cttcaaaatt
    20761 atagttatct tctagtaaag gaggagcaat ctgccaaggc gctgcttgct catcttgttc
    20821 cgctgaatga taccaaatat tccattcatc aaaggacagg ttgatctgct tcttactatg
    20881 tttcttcgcc ttgactgtat cgcacatcgc tgtcacttca gaaatgaacc gatccatgtc
    20941 taaggaacgt gcaagataat gagaaagatc atttttttgg ttgccataat attgatgcag
    21001 agacaaataa tctatttgat cgtacgcttg atcaagaact gttaactccc aatcaccaaa
    21061 tgtaggcatt tgccgattcg aacttccgca taaaaccacc tcaattgaat catctacgag
    21121 tttcatcgcc ttagccgttt cctctgctaa ccgtccatat tcttccgctg ttttatgtcc
    21181 aatctgccaa ggaccgtcca tttcattccc taaacaccat gtcttaattc caaaagggct
    21241 ctcttgacca ttcgaacgcc ttaaatcact ccaataagtt cctttaggaa aattacaata
    21301 ttcgactaaa ttacgagctg catctactcc acgagtaccc agattgacag ccatattgat
    21361 ttcggccccc acatgctgac accagttata aaattcatga atcccaactt cattcgtttc
    21421 aattgtccgc caagctaaat ccaaccttct aggtctattt gctatgggcc caatactgtc
    21481 ttcccaacga aatcctgaca caaaatttcc accaggatat ctaatcatgg gaatgttcaa
    21541 ttcttttacc aagtgaatga cgtcttggcg aaatccactt ttattagctg atggatgatc
    21601 tggctgataa atcccttcat atactgctcg tcccatatgt tcaataaatg aactgtacaa
    21661 ccgcggatca actttgccta cacgcttgac actactaatc aacattgtgg cttccataac
    21721 tgacctcctt taatttatac atgaataata cacctcgttg aaagcgttgt caataatata
    21781 aatgttaaac ttacttattt tttatcgatt ttaattaacc aaaatattaa taatgattaa
    21841 aacaaataat ttaatataac ttttattaac aaatatgtta atatataaga aaaacctttt
    21901 aagaggtgat atatatgcaa ctacaaataa acgaagaatc cttaccggta tatgaagcat
    21961 tagctagtaa aacaaggatc aagatcatcc agctactttc caaaaaaaag atgaatgtca
    22021 aagatttggc aaaagaactt ggagtgagca gtgctatcac gacgatgcac gtgaaaaagc
    22081 tagaggaagc aaacatcatc aaaacagaaa aagtaggaca acaaaaaatt tcgagccttc
    22141 gtgtcgataa aatcgatatc agttttccag aaaaaatatt caatgctttt gatacgaaag
    22201 aaacatcgat acctattggt cactatacaa attatgcaat tgaaccaaca tgcggtttag
    22261 ctacgatcca tgattttatc gggaaagtgg atgaaccacg ctattttatg gatcctcgaa
    22321 ggatggatgc ccgcattctc tggtttacca gcggatttgt cgagtatcag gcacctaatt
    22381 ttttaaatac agaggataca ttggagatgt tggaagtttc tgtggaaatt tcttctgaat
    22441 ttcctttttc aaatgacaat tggccttcag atatcacttt cagcctaaat ggtgtggagc
    22501 taggaacatg gacgagccct ggagattttg ctgatatccg cggtaaatat acgcctgatt
    22561 ggtatccaga taatcttaat caatacggct tgctgaagac gatccgaatt accaaacact
    22621 tgacgaatat gaatggagaa cccttgtcaa acatcacgat caacgacatc cctaaagagc
    22681 aagacacttg gcatttgcga atcgaagtga aagacgatgc caaacatgtg gggggctgta
    22741 ctttatttgg taaaggattc ggtaattacg atcaggatat caaattaaaa gtttactaca
    22801 gctgatattt ttcttttcta ttttataaaa caaaaacagc caatccctat gaagggacgg
    22861 ctgtttttgc tttattgtta tttccagaaa tcatccaaaa cggaaattgg caaatgtcgt
    22921 ttatgttgtg tcttgttcca ccatgcttcg attttttctt gtgcttgagc gggaacttct
    22981 tttccttcta gataatcatc aatttcatta tatgtgacac ctagtgcgac ttcatctgca
    23041 atcattggtt tcccatcttc aagatctgca gtcggaattt ttgtgtataa tttttccggt
    23101 gcattcaatg cttgaagcaa ttgtttccct tgtcgtttgt ccaaacggaa taatggcaaa
    23161 atgtcggctc caccatcacc aaatttcgtg aagaatccag taatgttttc tgcagcatga
    23221 tctgtcccta atacggctcc tgctctttct ccagctacgg catattgcgt aatcatacgt
    23281 tgacgtgctt tgatatttcc tttgttaaaa tcgctgattc ccacacctgc ttcgcttaat
    23341 acttgtactt gtgcatcaac agctggtttg atatttactc gcagactaac atcgggctgg
    23401 ataaagtcaa gagcagcttt tgcatcttct tcatctgctt gttcaccata aggaagacga
    23461 acagcgataa attgatagtt ttcatctttt gtttcttcac gcatttcttc catcgttagt
    23521 tgcgccaaac ggcctgctaa agtagaatct tggccgccgc tgatacctag tacaaaagtt
    23581 ttaagaaacg gatatttttt caaatatgct ttcataaagt caatactttt acgtatttct
    23641 tcttttggat caattgttgg tttgacacct aattcattga taatttctgt ctgcaggctc
    23701 atttattctc ctcctatgct tctgtatgaa gttctgctac gctttttttc attcgttcca
    23761 tgatagccat tttatggttc cagcattcag tagacagatc gactgggtat ttttgcggat
    23821 tcaagtctcg tttatactct tcccatagtg aatctagatt ttcttttgta tattctttga
    23881 tttcgtttag tgcaggtaat tcgtaaactc tttttccttc gataaagata tcttgtaaaa
    23941 ctgggcgagc tgtaaagtct cgaacagttt tattgataaa cgtatgcact ggatggaaca
    24001 tgaagatagc ttcttcttct cgagggtctt catcccataa tgtcacgtag tctccttcag
    24061 atttcccatc aaaatttcga gtgatgcgcc acacttgttt tttccctgga gtagttactt
    24121 tttctgcatt gcttgataac ttgatcgtat ccatcatttt tccttcatca tcttcgatcg
    24181 atactagctt gaatactgca ccaagggctg gctgatcata ggctgtgatc aattttgtcc
    24241 caacacccca tacatcaatt ttagcttttt gcatctttaa attcaaaatc gttgcttcat
    24301 ccaagtcatt cgaagcatag atttttgctt ccgtaaatcc ggctgcatct aattgttccc
    24361 gaacacgctt agatatatag gccatatctc cactgtcgat gcgtacgcct tggaagttga
    24421 ttttgtcacc taattctttc gccacgcgaa tcgcacttgg cacacctgat ttcaacgtat
    24481 cataagtgtc gactaagaac acgcagtctt tatgggtttt agcgtaggcc ataaatgctt
    24541 cataatcatt tccataagat tggactaacg aatgagcatg ggtcccgcta gctggtatcc
    24601 caaatatctt cccagcacgt acattgcttg ttgcatctgc tccgccgata tatgccgctc
    24661 tagttcccca gactgctgca tccagttctt gtgcccgtct agttccaaat tccaatagtg
    24721 gatcttctcc gatgacagat ttgatacgag ctgcttttgt cgcgatcaac gtttggaaat
    24781 tgaccatatt caacagtgct gtttctacta attggcagtg cgctaaaggc ccttccactt
    24841 ggattaatgg ttcatttgca aaaactagtt ctccttcacg agcagaacga actgttgctt
    24901 taaattcaaa attttgtaaa tactccaaaa aaccttcagg atagacttct aatccacgca
    24961 agtaagcaat atcggaatca ttgaacgtca gattctctaa ataattgact aaccgttcca
    25021 atcctgcaaa aaccgcgtat ccgtggttaa aaggcatttc tcgaaagtaa cattcaaaaa
    25081 cagcatgtaa atcagctcga cctaattccc agtatgtctg catcatattg atttgatata
    25141 gatccgtatg cagcgtcaaa ctgtcgtctg ggtaagtatt attcatcttg tattactcct
    25201 cttggcaagt tttcatttcc tacccattat aacaaaaaaa attaatagga aaagaaatct
    25261 tccatttttt ctgaaaaagc acatgtttta cggatatttc ttgctaaaaa tgaactccat
    25321 ctgctaaaac tatcctttct tattggtatt taacctaaac gagaaagaat acttatttta
    25381 ttcaatgtat ccgagacacg aagaaattag cgttttctat ttttcttact tgataaaata
    25441 agtagatttt cctactacaa tcgtagccgt taagataccg atgattgaac aaatataacc
    25501 aaatgtctct acaacataat caatggcaaa agtttttgaa gcaataatac gtctttcctt
    25561 ttttgcttct tatccccaaa gaaacggata taacttatta tgtattgaat ttttttggaa
    25621 aggcgaatta tgacaagata taccttgcgt tgaaaaaact cgcggaaaaa atatcacacg
    25681 tttttaaaaa gatacaaagt aagaaagcag ctgtcaatag aatggaaaca aaaatggcga
    25741 gacatcaatc agtctcgcct tgttttt
//
LOCUS       DAFBSV010000037        25739 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.038, whole genome shotgun sequence.
ACCESSION   DAFBSV010000037 DAFBSV010000000
VERSION     DAFBSV010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.038"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(1039..1704)
                     /locus_tag="LLB18_001408"
     CDS             complement(1039..1704)
                     /locus_tag="LLB18_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5244417.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            1884..3866
                     /locus_tag="LLB18_001409"
     CDS             1884..3866
                     /locus_tag="LLB18_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBK5244418.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            3870..4508
                     /locus_tag="LLB18_001410"
                     /pseudo
     CDS             3870..4508
                     /locus_tag="LLB18_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            4536..4964
                     /locus_tag="LLB18_001411"
     CDS             4536..4964
                     /locus_tag="LLB18_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244419.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            5421..6332
                     /locus_tag="LLB18_001412"
     CDS             5421..6332
                     /locus_tag="LLB18_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBK5244420.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            6549..6986
                     /locus_tag="LLB18_001413"
     CDS             6549..6986
                     /locus_tag="LLB18_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244421.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            7081..7965
                     /locus_tag="LLB18_001414"
     CDS             7081..7965
                     /locus_tag="LLB18_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBK5244422.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            8189..11356
                     /locus_tag="LLB18_001415"
     CDS             8189..11356
                     /locus_tag="LLB18_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244423.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            11376..11921
                     /locus_tag="LLB18_001416"
     CDS             11376..11921
                     /locus_tag="LLB18_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HBK5244424.1"
                     /translation="MNRIWNKSHRNNCSLLMILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILI"
     gene            11949..12404
                     /locus_tag="LLB18_001417"
     CDS             11949..12404
                     /locus_tag="LLB18_001417"
                     /inference="COORDINATES: protein motif:HMM:NF023225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HBK5244425.1"
                     /translation="MKLKKAYADQSDGRNVIKANLQNPNASYMFGLTTSVEIYKKETK
                     EPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKGAWKEKRWNLHTDFEITD
                     DAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFILKERRKKK"
     gene            12401..13159
                     /locus_tag="LLB18_001418"
     CDS             12401..13159
                     /locus_tag="LLB18_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBK5244426.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(13245..13985)
                     /locus_tag="LLB18_001419"
     CDS             complement(13245..13985)
                     /locus_tag="LLB18_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5244427.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            14046..15299
                     /locus_tag="LLB18_001420"
     CDS             14046..15299
                     /locus_tag="LLB18_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBK5244428.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            15621..15848
                     /locus_tag="LLB18_001421"
     CDS             15621..15848
                     /locus_tag="LLB18_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBK5244429.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            15971..16297
                     /locus_tag="LLB18_001422"
     CDS             15971..16297
                     /locus_tag="LLB18_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBK5244430.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            16365..17078
                     /locus_tag="LLB18_001423"
     CDS             16365..17078
                     /locus_tag="LLB18_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBK5244431.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            17388..18239
                     /locus_tag="LLB18_001424"
     CDS             17388..18239
                     /locus_tag="LLB18_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBK5244432.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            18360..20225
                     /locus_tag="LLB18_001425"
     CDS             18360..20225
                     /locus_tag="LLB18_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK5244433.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            20273..21682
                     /locus_tag="LLB18_001426"
     CDS             20273..21682
                     /locus_tag="LLB18_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBK5244434.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            21790..22491
                     /locus_tag="LLB18_001427"
     CDS             21790..22491
                     /locus_tag="LLB18_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK5244435.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            22650..23129
                     /locus_tag="LLB18_001428"
                     /pseudo
     CDS             22650..23129
                     /locus_tag="LLB18_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            23977..24552
                     /locus_tag="LLB18_001429"
     CDS             23977..24552
                     /locus_tag="LLB18_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HBK5244436.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            24552..24992
                     /locus_tag="LLB18_001430"
     CDS             24552..24992
                     /locus_tag="LLB18_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBK5244437.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            25008..25709
                     /locus_tag="LLB18_001431"
     CDS             25008..25709
                     /locus_tag="LLB18_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBK5244438.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
BASE COUNT         8697 a         4189 c         5320 g         7533 t
ORIGIN      
        1 atcaaggttc ctagcctttt tataataaaa tgaagcgaaa ataatttctt ttaaagagcc
       61 gagattatca gctatataag agtgaatttg atgcaaaaaa cagagccgaa acagtcttgg
      121 tgttcgtagc tctgcttata tgtttcgaat ttaagacaaa gagttggcaa aagatgttga
      181 taaggaagat aagataactg tgttatataa actaggtaac taactgtaac aagctaattt
      241 taagagattc ttattagaag acgtttagga atataactaa gaaaatgatt atacaggtaa
      301 ttgtcatttc aataatgttt tctaattttc gcgtctttgt tttaagaaaa aggccagaat
      361 cagttggaaa aaagttcgta cgatagtgaa gaggggcaaa atttcctact aatattccca
      421 ctaacaagag ataaaacggc caggttggtg tgattcctct ataaaaaaat gcccatgcta
      481 ccgaaatccc atagattaac aactgaacaa tttttacaat gaaaaaattg ttctgccatt
      541 actcaaagtc tcttcctcct tgtatcgttt atttgtttca ttttatcatt atgataggcg
      601 cttgaacaat ccattttgta ttttattgag tactcttgga taaactacca gcgattatca
      661 tatttattta tgttactgta agccatcata taaaagtaaa tgagcagatc atagaaatat
      721 aaaaaagaac taaaattgat ctaaattatg tgcagcttga ctacgtacca atctatatta
      781 cttactagat tggtcgttaa tctattcgga tcgaatgagc aaaatatttt tgtgaatgtc
      841 catccttgat tatgattcca aaaagaatca ttgggaggct gtggcgtaaa tattatacta
      901 taagccagaa atacctatca ttctgaactt ttttatttag gaactttcat ctcaaggctt
      961 tttcaattaa tttgtacccc tgttttttgg ataagatcat gtgcattgat tttttctatc
     1021 tctacgttca tctcctactt aatgcctatc tggctcctga gggcttcttt ttaaggcgtc
     1081 gtcatagtct tggctgagga tttcttggta atctgaggga atggcttccc aagtgagcag
     1141 gcgaacgttc atgacgtgtt ttcctttgtg tttgattaca gcatggtttt tctctttttc
     1201 tacctctcca gcgtgaaaag acagccatgt accatggcca aagatatcat tacataccca
     1261 acgttcgatg gaattgtcca cgtatcctac agggagtgtg gtatagccga tttgtggttt
     1321 caaaaaagga ttgaatcgat cgatcgtttc atttttgtat tgataattga taagaaaaag
     1381 atagaccaaa caaaagacga gcagaaagaa agatagtgtc tttttgagtg agaagggttg
     1441 ttttgatgaa taagatttct tgttaacaag aggttcatct ggcaatgttg gttctattga
     1501 ttcggtagct gattcaatag aaggaaaatc aatcggcaga cctaaagtat gatgtaaaag
     1561 tgacagcatt tcaaggtctg gcattgtacg agaattttcc caactagaaa tcgttttatc
     1621 ggaaacacca attttttcgc ctaattcttt ttgcgtaagc ttacaatttc tgcggtaagt
     1681 tcgtattttt tctccggtgt tcatcttctt ctcctttcga ttctacagta tatagattta
     1741 ttctacatga cctatacact tgatagatac gtttttttga tgaaaaacgg tatgatttta
     1801 tcaaagaatc atttaagtaa gggagagtgg tgataatcaa aaaaaagttc acagttttac
     1861 tcacaatcat agtgaccggt atcatgagtg gttttgcctt ggttagtata aataaacagg
     1921 tactctatcg gacaaatgaa tttttccatc aaacagatac ttatactccg attcgattgc
     1981 cacaacattt tattgggcaa gaagaatatg agcagctaat catggtattt gaaaatgtct
     2041 catcagaaac tgagctttct tatatgaaaa aaacagtaaa tgaatccaat gaagtagata
     2101 catcttggaa cttcaagata cagccaaagc ttgaaatgac attgtattat caaggggatg
     2161 tcaaatcttc tcacgagaag gtaccctatt ctaatacctc ctttcgcgta acgtccattg
     2221 aagaatcgat caaaataaaa gattttgaag gtgaattttt cttgatgacg agagaaaaag
     2281 aagcctatga acggttcatt tcactattca ctgatcgatt caatcaagca tttcacactg
     2341 attatgccac taatattttt gaagactttg aaaatagcta ttcgtattcg gttatttcaa
     2401 atacagacgt atataattat cgagtgtatt taactattgg attgattctt ttattccttt
     2461 tgttatcatc ctttttctta ttgatgaata aagaaatcag tttattgttg aataatgact
     2521 tttcattaca tcaagtattg tggtgtttat tggggaaaaa gaaaatcatt attacattca
     2581 taattgcagg aatcattggt ggttttattt ttatgtatta taaggagcaa tttctttatt
     2641 tgttccagat gtacgttttc ttgttcagcg gaatatatgg tatctctttg atttctcttt
     2701 tattagttga aaaaatcgct tcgttaagag aagcgttcaa ctatatccaa tacattcttt
     2761 ttacatttgg attgttgttt tctcttcttt tgaccgttgc caatgtcgaa ttagcaacta
     2821 tcgttttttc ttcttcacag ttagctgttt cccatgaacc accaaaagaa atcgctggtg
     2881 aggactatca tgtattttat ccagtaacca tcgggaaaaa ccacgtggat tttatttatt
     2941 ccaatcgttt tgcatcagca gcagatcagg aattatatga aactttgaat aaaaacggaa
     3001 gtatattagt caatgtatca gattacttga atgaagaaaa tgaacagttt ggcagaggga
     3061 taaaaataaa tctgaattat cttaagaaat ttcctttgat tgatgtctct ggaaggttga
     3121 tccaaataac cgaaaaagaa acgcaccctg ttatattgat ccctgaacga tatagacata
     3181 cagatttaaa aaatgacctg gcgcaaataa cagaatatta tcaagaaatc agtgaaaaag
     3241 aaccgaaatt tctatttata aaaaacaatc aacccattta tacatttatt ccttctatcc
     3301 cctggatcga acattatccg gttgttgaaa tactgacatt gaaaaacagt atgtatttgg
     3361 aaagaaatat tctcagcgga gaaatctatc caccgttaaa gatcaagata ggctctttgt
     3421 cgaaagaaag gttatttgag ctgattgaag aaagtcagtt acgtgataac ttgcagttat
     3481 catttccgta tactcagact gaagagatag ctgtcaaagt gttaagcaga tcatttcatt
     3541 acttgataca gatattttta ctcactttct tttctttctt cttgttgagc tatgtcatgt
     3601 tatgcatata ttttgtctac aattgtcgga aaatcgctat ctttcgttca agtggttatt
     3661 cgctctttga aacgtataaa gatttcttca tgatgaacct catcaaatgg ggaacgacaa
     3721 gtgtaatctt cctttttctt atagaaagag agcctaaata tctttttaat atttttttct
     3781 ttagcttcat tgattttatt ctttcagttg tttttatttt gtctacagaa aagaaaagtc
     3841 agttattgct gatgaatgga ggttaacaat tggagccgtt gatagtgata aaaggtgcga
     3901 aaaaaatcat ttgaaacaaa acgattcttc atttggatcg tttcactgcg gatgctgggg
     3961 atcttgtgac tgttgttgga gaaagtggag caggtaaaag tacgttattg aatatattag
     4021 gattgaatga tcagttcagt tcaggacaat tctatttgtt cgatcaagag acgaaacaat
     4081 taactgggag agagaagcgc ttgataaaaa gaaataccat atcttttctt tttcaagatt
     4141 ttgggttgat tgaatatgaa acaatcgatt ttaatttaga tattggattg aagttttcga
     4201 atttaaatgt ttcagataag cgaacagcaa agtatgaggc attgaaaaaa gtaaatataa
     4261 acaagaagct aagtacgcct atctacacat tatctggtgg tgagaagcaa agaatcgcct
     4321 gtgcgagagt cttattgaag aatagcaaaa tcattttagc cgatgaaccg actgggtcat
     4381 tggataaaag aaataaggat aaagtagttg aaatcttatc gcaacaagct tcccaaggta
     4441 cgttagttat cgtagtcacg catgatccat atctgaccaa aataggaaac aagaagatca
     4501 tgctttaaaa atcaaaaagg aaaggatgtc gttttatgaa aaaagcagtt attatttgtg
     4561 cactagggat aggttttgtt ggaggaaacg ctatgtcatc tgaagtggaa gcaaattcag
     4621 ttcacggtga aatctattac aaatctttaa agccaggaga gattcatttt gatgctaaag
     4681 gtaatattat taagtcaaat ttaccagtag accgggaaat ttctagaaca gcaattaatc
     4741 atagctctgg aagatgggtt tattatagtg atacaacttg tacgagaaaa acaggtcatt
     4801 ctaaccacta tagtcgtgtc tataatcgtc acggtgcaaa agcgaaagtt ggaaactcta
     4861 ttcgatcagc aaatgcaaca aaaggagtat gggcctatgc aagtgcgaca ggaaatagaa
     4921 ctgacacatt ctcatgttgg tacaatccaa ccggttggta ttaagtatcc aaaagtttat
     4981 ataaaataga aaaaacatat aatgaaacag cgttaaaagt tatttttggt agttttaata
     5041 tattcatttt tagttgtata aaaatatatc ataataaaaa caacaaaaaa atgtctggaa
     5101 aatcgaacat aaaagtgtct gatttgaata tcccagcagc ggaagaagaa aaacaaaatc
     5161 gataacattt gttctaagaa ttagttacgt taaatacgga acgcaagata gacttgaaaa
     5221 acggtaacaa aagaagtagt atattaaggt gtgatgtgct acttgacatt tattctgctg
     5281 agcgaacttt ctggattgtg tagccttata tctattcagg acgtatcgag cagattagta
     5341 aaggtgttct tgatgatttt catcttgaac acctttgttt ttagcaattc gcaaaaaacg
     5401 aaaagtagga gaattgataa atgaaaaaaa gatttttagc acttgccatc gtactaggca
     5461 ctggcttatt gtcaggctgt acgaatgccg gtgaaaaaac agccgttagt tataaaggcg
     5521 gtacaatcag cgaacaagaa gtaatggata gcttgaaaaa aatgcaagga gcagattccg
     5581 ctgtgcaaca gttgatcgtt tatcaagtat ttgaagataa atatggagat gacgtatcaa
     5641 ccaaagaaat cgattctcaa tatgatcaaa caaagaaaca attgggtgat tcatttgatt
     5701 cacaattgaa atctgcaggt tacacagaac aaacattcaa agacagtatc aaacaaagtc
     5761 tagcctttca agaaggtcta aagaaacata tcaaattgac cgatgaagat ttaaaaacgg
     5821 cttgggaatc tttccatcca gaagtggaag ctcaaattat ccaagtagca agtgaagatg
     5881 atgcaaaaga tgtgaagaaa gctgctgata agggagacga tttctctaaa ttagccaaag
     5941 acaagtcaac tgatactacg acaaaagaag atggcggaaa agtgaaattt gattccacta
     6001 ctacaacggt tccggcagaa gtcaaagaag cagcctttaa gttgaaagat ggtcaagttt
     6061 ctgatgtgat cacttctacc aatgcttcaa cttatactac ggaatattat gtggttaaaa
     6121 tggtgaaaaa ccaaaacaaa ggcaacgaca tggataaata caaaaaagaa ttgaaagaaa
     6181 ttgcaacaga cacaaaatta agtgacagta ccttccagaa taaagtaatt ggcgaagtat
     6241 tgaaagacgc taatgtaaaa atcaaagaca aagactttga aaatgttttg agtacattca
     6301 cttcagattc tagtacagca agtagtaaat aagcggtata aataaaaaat atgaactatt
     6361 taaatcaata aaactgttca tctaaatctt tttattagaa ctaaatcaac agtagtttaa
     6421 ttactacttg atttagttct ttttatttta aaaatttttt ttacttagaa tccagcgacc
     6481 ctagatattt ttctgtataa tcttaaataa agaaaacaat atcaaaaaat gcacgtagaa
     6541 gtagataaat ggagtggttt tgcaaatttc ttttatttct agaagttatt cacgtatacg
     6601 gatttgtttt tctcacaaat aaaaaggcag gaagtacaat ggatcatttg tatataaaat
     6661 atattcatca attttccgtt ttggtgttag gcacactaat tatagcgggg attgtcgcat
     6721 ttattattca aggccgtgac atattaacag tacatcaaga gtttttcagt tatgcatttg
     6781 gtattcctct gatcgctata aggtctgata acaaaaagtg gaagaaacgc tattacattc
     6841 tcttgctatt tttgtgtttt tatctgccac ctaagatttt tactttatta ggtatacaat
     6901 gcctatcatt ttcttttatt tcctatatca ttgttttaat tttcctcagt ttcatagtat
     6961 ggatgtttta tcttgtcaaa aaataaatga atgtttcatg aacagtactt catcacagcc
     7021 taattttttt ctttatgcta tcgttatatt aaagaaatca atcagaaggg aaagaaagtg
     7081 atgaaaaaag ttttattagt ggtaaacccc agttcaggcg gtgaacaagc aaaggaattt
     7141 gagcaattag cgatagcaaa attggaatcg gtgtttgatg aagtggtcgt cttgcataca
     7201 aaaaaagcag gggatgcaaa aaactttact cgcgaagcgg ctacggaagg gtatcatagt
     7261 gtgtttgtca tgggcggaga tggaacagtc aacgaaggaa tcagtggaat cgctgaacaa
     7321 gaacatcggc caaatttcgg atttttccca ttgggtacgg tgaatgactt ggctcgagca
     7381 ttagggatac cgctagaacc tgaggaagcg atcaatcatt tttcgattga atcagtcaag
     7441 ccattggata ttggaaaaat aaatgacgac tattttatga atgtcgtcgc aattggctct
     7501 atccctgaat caatcaatga tgtagatgcg gagaagaaga cgaaatttgg aaaactagct
     7561 tatttcatgt caggaatcaa acagttagct tccacacaat cctactcgtt tcacgtagaa
     7621 gttgatggaa agaaggaaga aattgagagc agtaccttgc tgataggact aactaactca
     7681 gtcggcggtt ttgaaacatt acttccaaat gcaaaagtgg atgatggtaa gctccatttg
     7741 gtttatttaa aagattcttc tttgatcgat acgcttaaaa cattgccaga cctattaaaa
     7801 ggagtagatg aatctacgaa aaatctagcc taccttactt gtgagcaatt agttgtgtca
     7861 ttagctgatg aggaagaatt gacgacgaat gttgatggag atgaagggga taaattacct
     7921 gtgacaatca aagtattgcc ctcacattta caggtttatt gttaaaatgg aggttgtgac
     7981 cgaggagttg gcgggagaac accgcttgtt cgggataagg gactgtgaca agacttttgt
     8041 cacagccttt tttttgtaca aaaaagaaat ttacacctaa tagaaaaatt tttccataaa
     8101 aatacatatt ttaaatatga aagtacaatt ggaaatagat taaaacgata aaataaaatt
     8161 gtcaaaacgt cagagaggat ggtggagaat gaatcaatgt gtaaaaaagc tgattgcgtc
     8221 gattttgttt gtcttccctc tcttgatggt gacatccgtt tttgccgatg tagagaaaac
     8281 aaacgaatca acgcaatcag agaatcaaag ttttgacaag actacttttt cagaagaatc
     8341 gattacttct gaaactacag aatctcaaag tgaggcttct actaataaaa ggcaagaaga
     8401 aaataagaca agtgagacct cagaagtagc tgaacaaacg tctgatagca gtgaagcggc
     8461 actggcaaga gctgtttcag cggatgggta cagcgaagct gccacaacag aagaactggc
     8521 gcagcttctc gcagacgaat cagtaactaa gatccgactg attcagcctt tgactttaga
     8581 cagggaatta gagatcaaac gagatatcgt tattgatttt ggtggattcg ctcacaattt
     8641 cggcacacac catatttata tcaatgagat acctcagtcg atcgagttcc agaattttaa
     8701 aggaacagct gcacatccag gtggattgac accaaatatc gatggaaatg ccattatcat
     8761 tgcttatatg accgattttt ggggaagcag atatcatttt acgggagaaa taaaatttac
     8821 cgggacactt gatttgtatg atgggtccaa attaggactg atttacgctc ctcgtgcaac
     8881 tgtcacatta gatggtgttt ccggtgtgtt ggatgtccaa ccagtgaagg aaggactgaa
     8941 tgccgctccg ggtaaagcct atttttgtag aagctatcaa ttgaatgtga tcaatggtag
     9001 tcaactttat ggaccgtatc tagggaaatt ctacggtttt ctagattcag gagatgagac
     9061 tggtagtgga aaaacagcgc caggaatcca tatcttaagc ggttcaaagg tctctcttga
     9121 ttatgatcgg gcagatggcg ttagcgatga aggagaggca gtcgatacgc tacctggtaa
     9181 tgtcatgttt gaagtcagtg gttcgggaag cgaattttcg gtaaatacaa agatcaatat
     9241 taccaatgac aacaatcgcg gaatcatcca aatgagaggt tcaggatcga aagtcactgt
     9301 atcgaatggt gggaaaatca ccatcaatac agcaactacg ggcggatttc gcttgcaagg
     9361 agattctagt caaatccatg tatcaagtgg tggacaaatc tcggtcaaaa tggctggaga
     9421 tgacgatcaa cccgggaaca atgggatgcg ttttgtagga aaaggccttt ctttgatcgt
     9481 agaaggagcc ggatcagtta tcgacatcga taagcagagt gggcgttcca gcgcagttcg
     9541 ttttgagaat ggtacgcaaa agctgacagt aaccaatgga ggctcattga gggtaagaaa
     9601 tacaggtgat ggcaaatctt acgtgaacag actcaatcaa ggaaatcaag cgatccaatt
     9661 ttatgacgct tctggttttc tagaaagtcc aggttcagct gattttacag tcactggaga
     9721 aaaatcaaat atcgatatac gcgcagattc cggagcaact gtagatacaa ctggagatat
     9781 tgatttaaat tttacggcag gtgaaaaaac ttatttagtc atggtcggga aaacagggga
     9841 agataagacc ggcatcatca gtggggatgt gttgaatgtg gacttagaat ctcctaccta
     9901 ttttgatttc caaaacaaac ggattggaag cgagaccaat ggcataggcg gctgggtatt
     9961 ccaaggaaat ggagattctt ctttaaagat cgcccattca gaaatcgctt tatggcgaaa
    10021 aacaggcgca acattcgata actttgaaaa agacccggat tatttttctg atatgacaga
    10081 cttatcgatc aatgggaccg acttaggcaa tttcgtatca agccctagtg caggtttaac
    10141 aaatgaattt gctcagacag gtgccggaat gaaaaattat aatcgaatca gtgccaataa
    10201 tcagctcccg atgattgaat ccttaagagt gccaacgaat gcagataaaa aaatctatgg
    10261 gcatgtcgtt gttcccgaag gtgtcgaggc aaagccaaga gatgcttgga caggcgaagt
    10321 agaagtgact ttacgtatta cttacgcaga tacgacgaaa tcatctgtag aaattactgc
    10381 tctcacgcaa ggacaaacag atgaaaatga aggggcagga tataacccat ggggagaagg
    10441 cgaacaaggc ggcttgttcg aagttcaagt acccaatgat gagagattaa aaacggagga
    10501 tcaagtgcaa gttgttgctg ctaaaaaagt aagaggtggc caagaagtga cagaactgga
    10561 ctctgccaaa acgacagtcg atgtgattcc tcctgaacct gctaatttaa gtaccacatt
    10621 gatcaatgca gcttctcgca cgatcacagg tacaggtgaa gcaggagcct tggtttcatt
    10681 gaaaaaaaat caagctgttt tgtcagaaac aactattgat gatacagggg aatttgttct
    10741 ttctatccca gaaaatcaac tttttgcagg agatgtatta gaaattgtat taaacgacca
    10801 agcaggagaa gctactgcta agggtgtgca gaacaagcca agtaccaacg atgaaattgg
    10861 gaatcacaat ccaagtgata cgccagttgt ttatcatgat gccccgcctt ttgcacctgc
    10921 tacgaagatc gtagtagaag gtggtctctc atttcttgcc ccttccaaac tcgattttgg
    10981 tcagatcaaa gcaactggtt tgacacaaga agcatttggc caaatggata tacaggaaaa
    11041 attatggatt tatgatcagc gagaaacgaa aaatccgtgg atcttaacga taaaattatc
    11101 tcagcctttc acaaatgatg caggattttc tatgcaggat gtcctatatt tcaagaaagg
    11161 agaggagtat caattagtga atgaagaaga actggaaatt gtcagaggac aaaattcaac
    11221 gaatgtgcaa gcagattatt cagaatattt aaataacggt cgggcgttta aacttgtctt
    11281 aaccaaagaa aatcagatag ctggtaatta ctcagcagag ataacatgga cattagcaga
    11341 tgcgccgaca gaataaagat caaggaggat gattgatgaa tcgaatatgg aataaaagtc
    11401 atcgaaacaa ctgctcttta cttatgatcc ttctccttgg attcatcctt tggcagacac
    11461 ctgtccatgc ctccgaattc aattttgcgg tagattttga attaccggct aatcagattg
    11521 ataagaacaa aacatatata aatgtaagga tggagcctgg gaaaacacag gaaatcccct
    11581 acacggtctt taaccgaaca gataaatcag taacagttga gacattgatc cactccgcta
    11641 cgacgaattc aaacggtgtg atcgaatatg gagaatcaaa aagtaaattt gatgaaacat
    11701 taagttatga tatgaaaaac ttagcaaaaa cagtgggaga aataactgtt cctcctcaaa
    11761 gtgcggtcac tgagacactt tcactgaaag cgccagaaaa agagctggct ggtgtggtcg
    11821 caggagggat cacgtttcaa gaaaaaaaag agaacgtttc taacaaaagt acagttggtg
    11881 tcgtcaatca gttttctcaa gtgaaagcaa tcttgatttg aaatagcgaa aaagagtctt
    11941 ccccagattt gaaattaaaa aaagcttatg cggatcaaag cgatggaaga aatgtgatta
    12001 aggcgaatct tcaaaatcca aatgcttctt atatgttcgg cttgactaca tcggttgaaa
    12061 tctacaaaaa agaaacaaaa gagccttacc tttcaataaa aaaagaaaaa atagatgtag
    12121 cacccaatac aaattttgat ttacttgtcc cattagaagg aaaaaaatta gctccgggac
    12181 attatcaagc ggttgtgaag ggtgcttgga aagaaaaacg ctggaatctc cataccgatt
    12241 ttgaaataac tgatgatgca gcggaccaat tgaatgaaaa ggatattgat ttaaaaaatc
    12301 agccagaaac atttgactgg cgatggctga tacttgttgg agtcattctt attggcttat
    12361 ttgctggatt atttatttta aaagaaagaa ggaaaaagaa atgaaaaaaa caattgcatt
    12421 aagtaccgtt ctagctggaa gtctattatt atgtacacaa agtgtttttg ctgagaataa
    12481 gagctcagcc actacagaag gaacgatttc tgtgaccaaa ccagatgctg caaatcctga
    12541 agacgttgtt ccagttcctc ctgttgatcc aaatgatcct gatactcctt ttacacctga
    12601 cgaaccaaat cagggaacat ccggattact gacgattgac caagctccag atcttgattt
    12661 tggaacaatc aagttaggta cagcaaaaac agtatatgct gcattacaaa gcggaacgga
    12721 cagtactgga gcacaaacac aagtacagaa tttcgtacaa gtaacggata aaagcggaaa
    12781 ttatgccggt tggaaattat cagtcaaacg aacagaattt attggtacaa catctgatac
    12841 gaataaacta actggttcaa aggtgaaatt caaaaacgcc gtgattcgaa atagcgcaac
    12901 taatagcagt ggaatgccat ctaccgtttc tggaactggc gctgaaggaa tcgaaatccc
    12961 agcagatcag gcagtagatc tagtaactgc aggagcaaat gaagggattg gcacatggat
    13021 ttattcatta ggagagaatg tggaacaagg gagacaatca gtggaattat ttgttcctgt
    13081 atccaattat gctgtagaca actacgtttc aacattcaca tggtcgttaa cagatgctcc
    13141 tacagaagag gaagcgtaaa atcatatcaa cgatttcagg gagtggagcc gattcaaggc
    13201 ccactccctg aaatctgcta tgcttacgtc tcagctctta ttcatcaact cgaagcagtt
    13261 ttttggaagt catggaaacg ttcctttgtc ttttcaaaga tctttcgacc aacgagtaag
    13321 gagtcaccgt tgaaaaattc taacacataa tgagcagaat caattttctg caattgcgat
    13381 aagttgatac agtaagattt taaaagtaaa aagtaagcat acttttctaa ctctgtcttc
    13441 aattgtttta aagaagtatt cactaattta tcttctgtag ttgttttgac cataacttgg
    13501 tttttcaaac ctttgatact ttcaatatat aaaatttccc gaggatacag gacgagactt
    13561 ccaccttttt gatcaataaa gattttatcg acatttacga tctgctgttc tttccaattg
    13621 atctgttcta gcacttgacg aatttgttca gataaattcc tgtcttttct gatatatcca
    13681 atcggaagga ttttccgatt gatgatctct actgcaaaat tcgtataagc ggtgaaaaaa
    13741 acaatattac tatgtgcatt ttttttacgt atttgttcgg cgacatcaat acctgtgagt
    13801 gattgcttca agtcgatatc gataaagaaa acatcgtgat tatcaatagt gcccaactgg
    13861 atcaactgat tgatttgaga gatagaagtg agctgcacga tattctcgat atgatgattg
    13921 accaattctc tgatgatcca ttcgctgtga aactggttat cttctatgat aaaatacttt
    13981 ttcatatgca ggctcctatt aaaaaaatat gtgtacattt tgaaacaaaa caatggagga
    14041 ataagatggt cgcaacagtg acactttatt tgacctttac tttgatttta gatttaggta
    14101 tctatttatt cttttcgaaa caactgctag taaaaaacag ctttggttgt atagctttga
    14161 tggtggtgac acttttactt cctatcccta aagtgagctt tccttaccta gttggcttat
    14221 tattgatgtt tcttttttat tttactacga aaaacctgtt tatcagctgt ttgatcagta
    14281 atcttttttt tgctatcact ggactcagct tttttctggt ttttgatctg atggattatt
    14341 taggaaagag acatcttgga acagcaagtt tttttgcact acttatcgca tttattttct
    14401 atctattagt aaaaagtata gacaaacaga cgagatttct caacttgctt tttacttatc
    14461 caactgaaca ctattttgga ggtatttgta ttttattaag ctggggcgtg atttacttgg
    14521 tattgggaag tgttcacttc cgctcatcta attatctgct tctatctctt ttgtcgatag
    14581 tcatcagttt tttttctttg tttttttcca ttatgttgat cagtttccaa gtaaaagaaa
    14641 gacaacatca ggaatcgctt caactgtatc aaataaatga agaatattac catcatctag
    14701 aggaattcaa acatgattat aaaagtctac tgttttcatt aaaaattact cttcaggaaa
    14761 ataaaaaaga aacgttggaa tttttagaaa tattagaaga tcattctgca gctatttttg
    14821 aaaaaccgca aatacaacag ctaacaaata ttgtatcccc agctgtcagg ggtgtctttt
    14881 taaaatttct agaaaaagca gaatcggaga aaatcccgat ccaagtagtt attcctgtcg
    14941 aagtgaaaac aatcccgatt gatctggttg tttttattcg ctgtttatct atttttattt
    15001 ctaacgcatt cgatcatcgt gtagccgatc agagtccgat tacgatcaat ctgctggaag
    15061 aaaaagaggg atcacgtttt agtatagcga acaaggcaaa tccaacgaat ttgacgctat
    15121 cggagatggt caaaagagga aaaacctcta aaaaaaatgg cgggttaggt ctatacagtg
    15181 cgaaaaaaat gttggatgtt tacgaaaatg cagaactaaa aatcgaattt tcaaaacaga
    15241 atcactattt ttttgtagaa atgtatctgg catctagaaa gagcaaatca gcctactgac
    15301 ttactgtcaa aggataagtt tgaggaaagt ctacacggag atagagacaa caacacagca
    15361 tattcaaaag aaacagaagc gtgatgaccg ttgtcaccct tctgtttctt ttgctatgta
    15421 gttaaacaaa gtagttgaca cttccgctac ttagtattag tacgaaagta tacttcatga
    15481 tactaagtag ataagaagtg aaaagcggaa cccacgatcg tcaaaatgct aactgctttg
    15541 cttacaccag ataaagggaa gagcaatatc gcttatttta ggcgtggaga agcaagcaaa
    15601 tccctacgat cacaaaaaaa atgctgaccc agcagttaag agagttagaa caagatgaaa
    15661 gtatccatcg aaaagcctat aaccaagtcc cgcctaaagt agagtactcg ctcaccgaag
    15721 aaggaaaatc attaagagag attctagtag cgttgtctgt ttgggaagaa gaacgtatcg
    15781 aaaaacaaaa agcctcaagg gaagaagaca cgctactgca tacacatggt ggctacctaa
    15841 attattgatt ttctatgaca tttattttaa ataaaagaaa acaggagttt ttttaaaagc
    15901 atcatctatt ttttatgtaa aaaaatggta tgattaatca agtaagaagt gattggaaga
    15961 aggcaagcaa atgaatagta tggaaaaagt caaccagttt agagatgaac gtaattggcg
    16021 acaatttcat aacgaaaaag atttggctat ctctatttct ttggaagcat ctgaattgtt
    16081 agaacttttt caatggaaaa cgccggaaga agtaaaagaa acacaattag aacgaatcaa
    16141 agaagaactg gcagatgtat tgatctattc atacatgatg gcagacaacc ttcacctgga
    16201 tctagatgag atcattgaag aaaaattgat caaaaataat ttgaaatatc ctgtagaaaa
    16261 aagcgcaggt gtacgaaaaa aatacacaga gttgtagaaa tgtgtcattc ggctgttgga
    16321 aagagcaaaa gaaaaacagt aaaatgagtc tggagggaga gaaaatgaaa aaaaaaggaa
    16381 aagcaaaaag atggctagtc aatatcctct tgttcctctt gttattagta ggactagctt
    16441 tgattttcaa tgaacagatc aaggattatt ttgtcagaga gacaggagat aaatatgcta
    16501 tagcgaatgt aacaaaagaa gatctgaaaa agaataacga taaagatgtc agttttgact
    16561 ttgatgcggt agaaccaatg acgacagaag gggtcatgag gtcgcaaatg agaggaacag
    16621 atctaccagt gattgctagt atcgcagtcc cttcagtttc aatcaattta ccggttttca
    16681 aaggcttgga taatacgtca ctactttacg gagcaggaac attatctcca gatcaagaaa
    16741 tgggaaaagg aaattatgcc ttagcaagcc atcgtgcaac gaaccctgaa ttgctgttta
    16801 caccgctaga aaatttagag atgggtgcca agatctattt gacagattta gaaaatgtgt
    16861 atacatacaa aacatttttt aaagaaaaag ttgctcctac agatacccaa ttactgaatg
    16921 aagtcgaggg aaaagaaatt gtcacactaa ttacttgtgg cgacatggac gccgtcacgc
    16981 gactagttgt acaaggagaa ctggaaagtg ttacatcgat aaaagatgcg acagatgata
    17041 tgagatctgc tttcaatcta gagacaaaaa cattttagga tactgggaca taagtcgtta
    17101 cagattaaaa acagccaaag gatatgaatc gataaggaaa aaccaatttg ctgaaaaaaa
    17161 gagaaacgca aagaggtgca tctctgattt ggttgttttc tagatagact tgtgttccag
    17221 tttttttatt ttttatatga aaaggcttgc ataaataaaa attcgatggt atgatgattt
    17281 tgaataagaa atggattgtt actgtacggc aggcaaaacc agaattcagc taagaaacag
    17341 taggcgaatt ctaggttttt ttatttttct tgagagggcg aagcaaaatg aaaattgata
    17401 aaattttgaa taacaatgtc gtcatttcga aaaatggatt cggggaagaa gtcgtttgta
    17461 tgggaaaagg actagctttt caaaaaaaga ttggggacga gatttcgcca gaagcggtcc
    17521 aaaaagaatt tgttttaaga gattcttttg ctaaaaacca attccagcag ctgatggctg
    17581 atattccggc agaggagatc gaatgggtca aacaagtagt cgaactggct gaagataaac
    17641 taaaagttga attttcgcct aatatttatc tgacattgac cgatcatctt cattatgcga
    17701 tcacacgagc aaaagaaaat atccaactgc ctaatccatt attatttgaa acaaaaaaat
    17761 tttatccgaa agaatatcaa gcagcgaaag aggctctttt gttcgtgaaa caaaagacgg
    17821 gtgtggaact ttctgaggat gaagccggtt ttattgcctt tcattttgtg aatagccaac
    17881 aaggaaacga agacatgcaa gtgacgatga ccgctaccac aatggtaaga gatatactga
    17941 gtatcatcag taaattcttc ggcatcgtgt tcgatgaaga atctttgaat tatcagcgta
    18001 tcattactca tctgcagttt tttgcccagc gttatctcaa aggggaagga tctgacgagc
    18061 aagatgaatt tctctacgca ttagttcaag gaaagtatcc aaaagcgttt cattgtgtcg
    18121 aacggatcaa tgagtatctt cgacaaacgc aaaaacagga aatggggatc gcagagcaga
    18181 tttatttaac gattcatatt caaagagtag taagtgagaa aaaaagcatc caatcataag
    18241 gattgttact gtatggcagg caaaacctgg attgaaaaaa taggttcacg aatgtttgtg
    18301 actgtttttt tcaatctggg tttttatttt ttaaataaaa aagaaagaag gaaaaaacaa
    18361 tggataatca agcagttggt cgtcgtgtat gggaagcggt aggaggacaa aagaatgtca
    18421 aaagtttagt acattgtgct acgcggttgc gattcagatt aaaagatgaa tctttagcag
    18481 atacgcaaaa gttaaaagaa gacccggacg tgatccaagt cgtacaaagt ggcggtcagt
    18541 atcaagtagt gattggcagt aatgtagcag atgtttatca atcgatcgtg gatgaggaag
    18601 gtcttgcagt ttcggaggat ggaaaagaag agtccaaaaa tattttgaat cgtctgatcg
    18661 atattatctc tagtatattt acaccttttc taggggcgat ggcagccgcc ggggtattga
    18721 aaggattctt atcattggca acggtgatgg gctggctgac agctgatagc ggtacttatc
    18781 aaatattgtt tgctgcagca gatggtgtct ttaccttctt acctgtcatg cttgctttta
    18841 cagcagctaa aaagttcaaa gccaaccagt ttttagcagt agcaattgct atggcacttg
    18901 tgtatccagc tatcacagca gttgctggtg cgggagaagc tatcagtttc tttgggatcc
    18961 cagtgattct ttcaccatct ggttatactt cttctgtcat accaatcatt ctagccgtat
    19021 gggttcaaag taaattagag ccattcgtaa aaaaagtgat tccgcaattt ctgcaaatga
    19081 ttttagttcc gcttgtcgtt ttagtagtga tggttccatt aacatttctt gctttaggac
    19141 caatcgggac ggttgccggt aatgctttag gcggtctctt caactcgatt tatggattta
    19201 gtccaatcgt agcaggtcta atcatgggaa gtttatggca agtattcgtg atgttcggca
    19261 tgcattgggg attcgtaccg atcatgtttt tgaatatcga acaatatggg tttgatgtat
    19321 tgatgccaat gcttcttcca gccatcttgg cacaaggtgg ggctgcttta gctgtagcat
    19381 tgcgaacaaa agatacgaaa cttcgagcat tagggatttc ttctacagtg acttcgttat
    19441 ttggaatcac tgaaccaact gtgtatggtg tgacattacc tttgaagaaa ccattcattg
    19501 ccgcttgtat ttctggaggt attggtggag ctattatcgg attttccgga gtaaaagctt
    19561 tctccagcag tttggtcagc ttattgacga ttccgacttt cattaatacg gtggatggtg
    19621 tagagtcaaa tgtgacagta gcagtaatag ctacaggaat tgcttttgtt cttgcattcg
    19681 taggtacatt gattttagga tttgacgaac aaacacaaga caatcaatta gaaaacaaac
    19741 atgcgaatgc aggagaaccg attacttcag cacggcatac cttaaaaagt cctttaacgg
    19801 gtaaagtact gccattgagt gaagtaccag accaagtttt ttcttctggc gtgatgggaa
    19861 aaggtatcgc tattgatcca gaagtaggag aactagttgc acctgcagac ggagagatca
    19921 cgactatttt tccaactgga catgctgtag ggatcacaac gactgacgga gcggagattt
    19981 tgattcatat cgggatggat acagtagaat taaatgggaa tggctttgag atcttagtca
    20041 aacaagggga tctcgtcaaa gcaggagatt tattgattcg ttttgacatc gaagcaatta
    20101 gagcagctgg ctatagcgta atcactccag ttgtcattac gaatactgat gcatttgccg
    20161 atatacttga attagaccaa aaagagatta ttgcaaacga agatgttctg gcaattgtaa
    20221 aataaggagg aaatcaggat gcaatcacgt ttttcagaaa aatttttatg gggtggagca
    20281 actgctgcca aatcaattag aaggggctta tgatcgagac ggaaaaggac tatccgttgc
    20341 agatgctatg cctggaggta agcagcgctt tgcgattatc ggcagtgaag aatttgactg
    20401 gacgattgat caagaaaaat atatttaccc gaatcatcga ggaatcgatc attacgatcg
    20461 tttcaaagaa gatcttgcct tgtttgcgga aatgggattc aaatgttatc gtttttcgat
    20521 tgcctggaca cgaatttttc caaatggaga cgaaggtact cctaacgaag cgggattaga
    20581 attttatgat cagctgattg atgagtgctt aaaatatgat attgaacctg tgatcacgat
    20641 ttctcattac gaaatgcctc ttcatttggc aaaagaatac ggtggctgga aaaatcgaaa
    20701 actgatcgac ttctatgaac gatttgctca gacagtatta gagagataca gcagtaaagt
    20761 caaatattgg atgactttca atgaaatcaa ttcggccttt cactttccag ctttaagtca
    20821 aggattagta aaaagcaatg gagcaggaga gtaccaaaat attttccaag catggcataa
    20881 tcaattcgtt gcaagtagca aagccgtaaa aatcggccac gaattgcgtt cggatatcca
    20941 aatcggctgc atgattatct atgcaacaac ttacagcatc gatgccaatc cagtcaatca
    21001 ggcagcaaca atgatccaaa accaagaatt caattttttc tgcacggatg tccaagtacg
    21061 tggagaatac cctgcataca cagcgcgtac ccataaaaaa tatggagtcg atccggaaaa
    21121 attagagcaa acggaaaaag acttccagtt gctaaaagaa tatccagtgg actacatcgg
    21181 atttagttat tatatgtcta cggcaatcaa tgagactgat ccacaagcag caacttcaga
    21241 agggaacttg ctgggaggag taaaaaatcc gtttcttgag gcaagtgaat ggggctggca
    21301 gatcgatcca gaagggctga gaatcgcatt gaatgaatta tacaatcgtt accagaaacc
    21361 attattcatt gttgaaaacg gtcttggagc cattgatcat atggaagagg atggcacgat
    21421 tattgatgat tatcggatcg attatttacg tcgtcatatc gaagcgatgg ctaatgcagt
    21481 agcagacggt gtagatttga tgggctatac gccttgggga tgtatcgatc ttgtcagtgc
    21541 atcaacagga gaaatgagta aacgttacgg ctttatctat gtggatctag acgatgaagg
    21601 aaatgggaca ctgaatcgat caaagaaaaa atcttttgat tggtataaag aagtaattgc
    21661 ctcaaatggc gtaaacttgt aattaaagca gctgaatgaa aaagaacaca cttctcacat
    21721 gtgatttgtg ttcttttttt attttttatg tgctattctt ttagtaatag taaagcaaag
    21781 ggtgacgtta tgaaaaggac acgtgtacta tacttggaag tcgcagataa aattaaagaa
    21841 gatattttct caggaaaata tccagtcggt tcgatgttgc cgacagaaag tgaattagaa
    21901 gaactgtttc aagtcagcaa aatcactgtc cgaaaggcaa tcgaactgct ggcatcagat
    21961 gaatatgtcg caaagaaaag tggtcgtggg acgacggttc taagcaatcg tccttacaat
    22021 cgattatcca aagcggcaag ctttacgcaa atcttggaga actcccgata tgaagtccgg
    22081 aaagaaacgc tggatttgca attggtccat ataaagaagg aagatccttt gttttccttt
    22141 ttcggtgagc aagctgtttg ttttaagcgc ttatattatt tgaacaatca gccttatatt
    22201 tattttgttc attatcttcc acaagaaatg atgcaattca gcagagaaga atttggcaaa
    22261 gaatctttgt atcgtttgct gacgaaaaaa ggatatacta ttgactcatt ttctgatgat
    22321 ttctcggcag tatttttaac agaagaagaa caaggaattc tgaaaacaga cgcacagatc
    22381 ggcatcaaac ggatacggaa atcgtctacg caaattgggg aaatgattga atattcggag
    22441 gcggtctacc atacggagct gcatccttac catattgatt atgaaacata aataaaaaaa
    22501 gaggttgtga aaaagctgcc ctgcatcaag taataagaac agccaaacaa aaatagcttc
    22561 tcatattttt cgtttggtta ggcttattac cgcagataca cggctgtttc tggattacca
    22621 tttattctgg ataagggggt gtggcacgat tttcagaagg aatctatgaa ccaatcactg
    22681 tattgatttt agcttcgatg gtaaccccat tcggcttgac gatcgcttat ttcttaggga
    22741 aaatcattcg taaaaatata ctcaatcgtc aagaaatcga tacattgaag accgcttttc
    22801 ctatggggat ctgtcagatc acagagggat gtttccctat cgtattgaac gacttggcac
    22861 gcaatgtcat agcaacggga gtcggtggga cagtaggtgg cggattaagc atgttttggg
    22921 gcgcagatag ccgtattccg gcatcgggaa tgtttgcagt cgctacgatg accagaccat
    22981 gggcattcat tggtgcattg ttagctggtt cttttgtcac aggaataacc attttattat
    23041 tgaaaaaacc agtggatccg aatgcagaaa tcatccaaga agaaaaagag gaagaagaca
    23101 tatcttggga tgatttgaca attagttagg agaggcagaa tggattacaa gaaaaaagta
    23161 caatagatgt accttgagac aggaatggta tgaaagaatc agagttagaa agaatcgaat
    23221 atacagattt tggtttagga gcgatcgaaa ctgtccagag catcggcacc ctccttgaaa
    23281 tgacgatgaa ggaaaaatga gaacctttcg ttgtcgaaag ggtctggtat accttatgtc
    23341 gaaggaaagg aaacaaaaaa actttcctgt actattccaa aaaggaaaga aagttattat
    23401 acagtaaaaa aagaaattat tcttcatgct agagatcagt acacgttcga gcccaatatc
    23461 aaacactagt tccaggcagg cgcaacaggt gcggttatca ctgaattttc ttccagcagt
    23521 gacgattcaa gtgatatttt tacaaatcca gctatttatc gttaacaaaa agatttttag
    23581 gagaagctga tgaacaaaaa tgatcaaatt ttgatcgttt agttcgtcgg cttttttatt
    23641 tagagaaaca tcatttatca gtgaaacata acacgagaac aaaatgattt tttcgttaat
    23701 aaaagaaaca agtatttgtt gtttaaaata atacacgtta ttggcatata ggacgaaatc
    23761 ccagtatctt ctataagtaa gtcatttcat atcgatgaaa acacgttatt tatttttgtt
    23821 ttatctataa aatggctgaa aaatgatttt tttctaaata ctatatatag tggcgtctat
    23881 cctatatacc actaaaaaac tacaaaatct agtcttttat tttaaaaaaa cacgtgtaga
    23941 atgaagatag acttttgagt tagggagtgt ttttttatga aacttactgt tttttgcggt
    24001 tcccgttttg gtaataaaga aagttacaaa tttattgcgc aaacgttagg aaaatacatg
    24061 gcacaagaag aaatcgaact ggtttacggt ggttcatact ccgggattat gggagtgatt
    24121 agtaaaacag tactggaaaa taacggaaaa gtcacaggta tctatccgaa tgggcttttt
    24181 gaaactgaat tgcctggaaa agatgttact acatttattc ctacagaaac gatcgatgaa
    24241 agaaaggtat tattatttga aaagggagat gctgtcctcg ttttccctgg aggtctaggt
    24301 acattggagg aattctcaca acttctttct tggatagcaa tcggtctgac gcccgacaag
    24361 ccaatcggaa tattgaatat tggcggttat tacagcggct tgcaacaatt attagaaact
    24421 tttgcaaaag aggattttat ggataaaaaa tggttggatc aagtaatctt ttccaacaat
    24481 ccattggaac tggtcaatga attacgagca gtatctatta aaaatcagtt attattgaag
    24541 gaggcaaaat aatgagtcaa atatatttag caggaccatt tttttcagag gagcaaatcg
    24601 atcgagtaag tcgtatcgaa aaagcgttgg aggaaaacaa aacagtcaca agtttctact
    24661 ctccacgtca tcaccaagaa agcaattatg aactattcag cgctggatgg gcgcaggaag
    24721 tatacgaaaa agatatggaa gaactgacaa atgcagaatt tgttgttgct atccttgact
    24781 ttgagcatca aacaatcgat ccaggaacgg cttacgaatt aggtgtggca actatgttga
    24841 aaaaaccgat gatcattgta caagaagaga cggtacctac gaacttgatg attacacaaa
    24901 gtctccatac gtatttaaaa tcagaccaag ctgtacgtga atatgatttt gaaacattgc
    24961 ctgttgaaac ttacgtaggc gagtacttat agaagaggaa gggttgtatg tcagtgattt
    25021 tgatttcagg aacgattggt gcaggtaaga gcagtttgac ggatatgctt gcaaaagaga
    25081 ttgattctaa accattttat gaaaatgtcg aagataacga agtattgccg ctcttttatt
    25141 caaatcctga gcagtacgct tttttattgc aaatcttctt tttgaacaag cgatttttag
    25201 caatgaaaaa tgctttagtg aacgatgaca atgtgctaga ccgatccatc tatgaagata
    25261 gcctgttgtt ccatctaaac gctgatttag gtcgggtaac ggatatcgaa gtacagcagt
    25321 acgatagctt attagatacg atgctaaacg agttagatga tgttgctcca aaaaaacggc
    25381 ctgatttgat ggtccatatc aaagtttctt tggacacgat gctagaacgt atcaaaaaac
    25441 gtgggcgtga ctatgaacag ctagaaagcg atgagacgtt atatacctat tatgaaacgt
    25501 tgaacacccg ctataatcaa tggtatgaag attttgatgt atgtcctaaa atacaagtgg
    25561 atggggataa attcgatttt gtagaaaatc cagaagatgc aaaaaaggtg atccgtcaga
    25621 tccaagaaaa attagctgaa ttggaaggaa agcctgctgg aaaatatttt acggataacc
    25681 agcatgcaaa aggtcaagaa ttaggctaaa aataaaaaac caaacgacgg gaaagaaaa
//
LOCUS       DAFBSV010000038        25374 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.039, whole genome shotgun sequence.
ACCESSION   DAFBSV010000038 DAFBSV010000000
VERSION     DAFBSV010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25374
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.039"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(124..501)
                     /locus_tag="LLB18_001432"
     CDS             complement(124..501)
                     /locus_tag="LLB18_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244439.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            757..1485
                     /locus_tag="LLB18_001433"
     CDS             757..1485
                     /locus_tag="LLB18_001433"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBK5244440.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1485..1739
                     /gene="purS"
                     /locus_tag="LLB18_001434"
     CDS             1485..1739
                     /gene="purS"
                     /locus_tag="LLB18_001434"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HBK5244441.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1741..2412
                     /gene="purQ"
                     /locus_tag="LLB18_001435"
     CDS             1741..2412
                     /gene="purQ"
                     /locus_tag="LLB18_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HBK5244442.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2413..4635
                     /gene="purL"
                     /locus_tag="LLB18_001436"
     CDS             2413..4635
                     /gene="purL"
                     /locus_tag="LLB18_001436"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HBK5244443.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4620..6059
                     /locus_tag="LLB18_001437"
     CDS             4620..6059
                     /locus_tag="LLB18_001437"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBK5244444.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6082..7134
                     /locus_tag="LLB18_001438"
     CDS             6082..7134
                     /locus_tag="LLB18_001438"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBK5244445.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            7131..7709
                     /gene="purN"
                     /locus_tag="LLB18_001439"
     CDS             7131..7709
                     /gene="purN"
                     /locus_tag="LLB18_001439"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBK5244446.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7706..9241
                     /gene="purH"
                     /locus_tag="LLB18_001440"
     CDS             7706..9241
                     /gene="purH"
                     /locus_tag="LLB18_001440"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBK5244447.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALVFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9257..10531
                     /gene="purD"
                     /locus_tag="LLB18_001441"
     CDS             9257..10531
                     /gene="purD"
                     /locus_tag="LLB18_001441"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBK5244448.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10653..11567
                     /locus_tag="LLB18_001442"
     CDS             10653..11567
                     /locus_tag="LLB18_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBK5244449.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11700..13265)
                     /locus_tag="LLB18_001443"
     CDS             complement(11700..13265)
                     /locus_tag="LLB18_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBK5244450.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13258..14709)
                     /locus_tag="LLB18_001444"
     CDS             complement(13258..14709)
                     /locus_tag="LLB18_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBK5244451.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14723..15739)
                     /locus_tag="LLB18_001445"
     CDS             complement(14723..15739)
                     /locus_tag="LLB18_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK5244452.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15959..17047
                     /locus_tag="LLB18_001446"
     CDS             15959..17047
                     /locus_tag="LLB18_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HBK5244453.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17101..18627
                     /locus_tag="LLB18_001447"
     CDS             17101..18627
                     /locus_tag="LLB18_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBK5244454.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18629..19834
                     /locus_tag="LLB18_001448"
     CDS             18629..19834
                     /locus_tag="LLB18_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK5244455.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20091..21068
                     /gene="guaC"
                     /locus_tag="LLB18_001449"
     CDS             20091..21068
                     /gene="guaC"
                     /locus_tag="LLB18_001449"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HBK5244456.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            21332..22756
                     /locus_tag="LLB18_001450"
     CDS             21332..22756
                     /locus_tag="LLB18_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBK5244457.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            23217..24326
                     /gene="pdhA"
                     /locus_tag="LLB18_001451"
     CDS             23217..24326
                     /gene="pdhA"
                     /locus_tag="LLB18_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HBK5244458.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            24329..25306
                     /locus_tag="LLB18_001452"
     CDS             24329..25306
                     /locus_tag="LLB18_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBK5244459.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
BASE COUNT         8202 a         4319 c         5704 g         7149 t
ORIGIN      
        1 aagcagatcc gttagcggtt ctgcttcttt tagtttatta tattttctta tcaataatag
       61 gaacctgatt ttaaaagcgg ctacctcttt accgtgcctc tttacataca aaaaatagag
      121 gaattaagcg taaatggctt ggctattata actaaaatgc tggttatgga gatgttgcag
      181 caagttttcg agaaaagcgt attccatctc ttgtccattg aataagatct ggatacgata
      241 atgatttttg aaacgcttct gttcatgaat ctgactgatt gaaagttcgc ctttgtgttc
      301 tgtctgataa agaaaagtcc ttttacggca ttcagcacag cgcttggttg ctcggcggat
      361 ttttcggaat gtataaaaac tagtatcttt attgcataaa taaacgtctt tgatcgacag
      421 caaatcatta tatagacagg aacgttcttc agctgttaat tctgataaaa aaagctgacc
      481 ttgttttatt gcatcttcca tcggcaagtg cctcctcgaa cccattatcc aaatttttag
      541 ttaattctaa tataccatca ttaagtataa atgtaaacgc ttgttgatgg tataagattt
      601 tcgtttctga taaaacacga acattaaaag aatctaatgc cttaaatgta catatttttg
      661 ttgatttata aaaagatgat tgctaaaatt taaagtgaaa aaacgaacaa aaaacgatgt
      721 atttgctttt aatgtaaata aaaaggagag acgtacatgg agaagaaaga acttttgtat
      781 gaaggaaaag ccaaaaaaat atatcttact tctgatgaga acttgatttg gatagaatat
      841 ttagatcaag caactgcgtt gaatggcgcg aggaaagacc agataagtgg aaaaggagaa
      901 ttgaataatc aaatcacaag tgcaattttc cgttatctga ctcaaagagg aataaaaaat
      961 cattttattg aacaattgtc taaaaccgaa caattagcaa aaaaagtaca aattatccct
     1021 ctggaagtgg ttatccgaaa tattgcagca ggaagtttct caaaacgtct aggtgttccc
     1081 gaaggtaaag aattcatcaa accaatcatt gaattctact ataaggatga ccagttggat
     1141 gatccattta tcaatgaaga gcatatctat ttcttacaac ttgcaaagcc ggaagaaatc
     1201 agtgagctga aagcccaagc gttggctatt aatgaaattt tgaccgaatt atttgctaag
     1261 gtcggtttgg ttttagtaga tttcaagcta gaatttggcc ggtcgaatgg acaaattttg
     1321 cttgcggatg aagtaacacc ggatacttgc cgattatggg atgaacgtac gaatgaacat
     1381 atggacaaag acgtttaccg cagagatcta ggtgatttga tcccagtcta tcaagaagta
     1441 tataaccgtc tatcggaact aactgaagaa aaggagcgag tatgatgtat ttcgtaaaag
     1501 tatatgtaac ctataaagat tcagtgttag atcctcaagg ggaggcagta aaaaaagcag
     1561 tccatcgtat gggatatgaa acaatcgaag atatccgaat aggaaaatac tttgagatac
     1621 aacttgctga tgcagaagaa ccaatcgata cagtgattga aacgatttgt gacaagctgc
     1681 ttgcaaatgt aaatatggaa acataccgat atgaaatcaa aaaaatggag gaagtataac
     1741 atgaaatttg cggtcatcgt ttttccaggt tcaaattgtg acgcagatat gttatgggca
     1801 gttcgcgaga tcatgggcgc tgatgccgaa tttgtacggc atgatgagtc ctctttagaa
     1861 ggatttgatg gggttttact gccgggagga ttctcctatg gtgactattt gagatgcggt
     1921 gcgattgctc ggttttctac aatcatggaa gaagtgattc gttttgctga agaagggaaa
     1981 ccagtattcg gtacatgcaa tggattccag atattgacag aagcaggact tttgccaggt
     2041 gtactgagac gaaatgagtc tttgcatttt atttgcaaaa ctgtaccatt gaaagtcaac
     2101 cccaagacgg cctttacttc agagtatgaa gccgacgaaa taatctatct tccagttgct
     2161 catggggaag gaaattattt ctgtgacgaa gaaacacttc aagaactaaa aaaaaataat
     2221 cagattgcct ttacttataa tgacaacatc aacggcagcg tggaaaacat tgcagggatt
     2281 acgaacaaag cagggaatgt gttaggaatg atgcctcatc cagaacgtgc agtagaagac
     2341 ttgctaggat cagaagatgg gaaacggttc tttgcttcca ttttaaaaaa cttcggaaag
     2401 gtgaccgtat agatgaaaac attgaaagaa ccgacagctg aagagatcaa gaaaaaaaga
     2461 atctatgccg aatggggatt gactgatgaa gaatatcgaa tgatcgaaga agatatctta
     2521 ggaagaatgc ctaattatac ggaaactgga ctgttttctg ttatgtggag cgaacattgt
     2581 tcctataaaa attctaaacc ggttctacgc aaatttccta ctagtggacc tcatgtgttg
     2641 caaggccctg gagaaggcgc aggcatcgtc gacatcggtg atggactagc agttgtcttc
     2701 aaagcagaaa gtcacaatca tccttcagcc gtggagcctt atgaaggagc tgcgacagga
     2761 gttggcggaa tcatcagaga tattttcagc atgggggctc gtccaattgc gttgctagat
     2821 tcattgaggt tcggcgaatt agataatcca agaacgaaat atttactaga agaagtagtt
     2881 gcaggtatcg gcggatacgg caattgtatc ggcataccga ctgtaggcgg cgaaattgca
     2941 tttgatcctt gttatgaagg aaacccatta gtcaatgcaa tgtgcgtagg tttgattgaa
     3001 cacaaacata tccagaaagg gcaagccgct ggcgtcggta attcgatcat gtatgtaggt
     3061 gcaaaaacag gtcgcgacgg tatccacgga gcaacttttg cctcagaaga atttaatcaa
     3121 gaagaagaac agcaacgttc tgctgtacaa gtaggcgatc cttttatgga aaagctgctg
     3181 cttgaagcgt gtttggaatt aatcttgcat cattcggatt ctctaatagg tatacaggat
     3241 atgggagcag caggacttgt ttcatctagt gcggaaatgg cttcaaaagc tggctcagga
     3301 cttatattga cattagatga agtcccacaa agagaaactg ggatgacacc ttatgaaatg
     3361 atgttatcgg aatcacaaga acggatgttg atttgtgtta aatcaggaga ggaagaaaaa
     3421 atccaagaac tatttcagaa gtatgatcta gatgcagtca ctatcggtaa agtaacagac
     3481 gacgggcaat atcggctata tcatcaagga gaagaagtag caaatctgcc agtcgatgca
     3541 ttagctgaag atgcaccagt ttatcataaa gaaatgaaag aaccagctcg aatcgtagaa
     3601 tttcagcagt tagctcctta tcagccagtt atcgaagaac ctggacaagt attgcttgat
     3661 ctgctgcagc aaccgacgat tgcttcaaaa cgttcaatct acgaaactta tgattcacaa
     3721 gtacaaacca atacagttgt ccgtccagga agcgatgctg ctgtgatgag ggttagaggg
     3781 acgaataaag cgttagctat gaccacagac tgcaacgcgc gctatctgta tttggatcca
     3841 aaaatcggag gacaaatagc agtggcagaa gctgctagaa atattattgc tagcggtggt
     3901 aagcccttgg cgatcaccga ctgcctgaac tatggttctc ctgataaacc agaagttttt
     3961 tgggaattat cgacttcagc tgacggaatt gctgctgcgt gtgaaacgtt aggaactcct
     4021 gttatttcag gaaatgtctc tttatataat gaaacggatg gtcaagcaat ctatccaaca
     4081 ccaatgattg gtatggtcgg attgattgag gatcataaac atatcactac tcaggaattc
     4141 aaaaaatcag gggatctaat ctatatatta ggtaagacgt ttgcagattt tgatggcagt
     4201 gaattacaaa agatgcagct tggaagaatc gaaggtgtga tccgaaactt tgatctatcc
     4261 attgaaaaga gaaaccaaga gttagtattg acagccatcc aaaacggatt gattgaaagt
     4321 gctcatgact gttcagaagg tggcttggca attgcactgg cagaatcagc tttcaaacat
     4381 cagctaggga tatctgtaca gtttgaattg tcctctgctc aattatttgc agaaactcaa
     4441 tcaagatttg tgttgacagt cgcaccggaa aataagacac gattcgaaga aatgatggga
     4501 gatgctgctg ttttagcagg taaggtgacg gatgaagcga taatcgaaat ttcagcaact
     4561 gacggtcaga tcaaaataga aactgcagta gcaagaaagt gctgggagga tgcaatcgta
     4621 tgtcttatga agtgaagagt ttaaatgaag aatgcgggat cttcggtgtt tggggtcatc
     4681 cagacgccgc tagtgtggca tacttcgggc tccatagtct tcagcatcga ggacaagaag
     4741 gtgcaggtat cgtgtccaat gatcgaggaa agcttaaggg gcatcgagat ttggggctgc
     4801 tttctgaggt attcaaagat caaagaaaat tgcagcagtt aacaggagaa gctgcaatcg
     4861 gacatgtacg ttatgcaaca gcaggcaatg gaagtgtgga caatattcag ccttttctat
     4921 tcaaatttca tgatcagtcg atcggcttag cgcataatgg taacttgatc aatgctcgtt
     4981 cccttagaaa agagttagag gaaaatgggg cgatcttcca ttctaactcc gatacggaga
     5041 tattgatgca tttgatccga cgaagtgaag aaacagattt tttaaataaa ttaaaaagtg
     5101 ctttgaatga agtcaaaggt ggctttgcct atttattaat gacagaaacg gcaatgattg
     5161 ccgctttgga cccaaatggt tttcgtccat tagcaatcgg acaaatgaaa aacggagcat
     5221 acgtgattgc ctcggaaact tgtgcattag aagttattgg ggcacgtttt ataagagatg
     5281 tccagcctgg tgagatagtg atcatcaatg acgaaggaat ccagattgat tgctttacga
     5341 aggacacgca gctttctatt tgttcgatgg aatatatcta ttttgccaga ccagattcaa
     5401 acatcgcagg gatcaatgtg catactgcac ggaaaaatat gggacggaat ttagcgaaag
     5461 aatcgccagt aaaagcagat atggtcgttg gcgtacctaa ttcttctttg tcagccgcaa
     5521 gcggttatgc ggaagctagt ggaatccctt atgaaatcgg attagtaaaa aatcaataca
     5581 ttgcccgaac atttatccag ccaacgcctg agctaagaga gcaaggtgtt cgaatgaaat
     5641 tatctgctgt acgaggagta gtggaaggta aaaaggtgat tatggtcgat gattcaattg
     5701 ttcggggtac gacaagcaga cggatcgtcc atcttttgaa agaagcaggg gcaaaagaag
     5761 tccatgtgag gattgcttct cctcctttga aatatccatg tttttacggg attgatattc
     5821 aaacgcgtaa agaactcatt gcggcaaatc acacgattga tgaaatcaaa gaatgtatcg
     5881 gtgcagattc tttaggtttt ttaagtgaag agggtctgat cgaatcgatc ggtctggaaa
     5941 aagatgctcc gtattcagga ttgtgtatgg cttatttcaa cggagattat ccgacgccgt
     6001 tatatgacta tgaagaaaaa tatcaggaat cactaaaaga aaaagtatcg ttcttttaaa
     6061 agcagaccaa gaagggagta tatgaattca atggcaaatg catacgcaaa agctggcgta
     6121 gatgtcgaag ctggatatga agtagtagaa cggatcaaga agcatgtcaa aaaaacggaa
     6181 cgtttaggta tgatgggcgc tataggagga ttcggcggtt gttttgattt atcggtcttt
     6241 caattaaaag agccagtcct tgtctcgggg accgatggcg tggggacgaa attagcagtg
     6301 gcaatcgaag cagacaaaca cgatacaatc gggatcgact gcgtagcgat gtgtgtcaat
     6361 gatatcttag cacaaggcgc agagccgtta tatttcttag actacttagc aacggggaaa
     6421 aatgatccgt tacgtttgga aaatgtagta aaaggtgtag cagatggatg tgttcaagga
     6481 aatatggcgc tgattggcgg agaaacagct gaaatgcctg gtatgtactc aggtaatgat
     6541 tatgatctag ccggatttgc tgtagggata gctgaaaaat ctcaattatt gacaggagaa
     6601 acgatcaacc caggagatgt gttgcttgga atagcatcta gcgggattca ttcaaatggg
     6661 tactctcttg ttcgcaaaat tttctttgag cagcagcagt tttctttatc atcaaaactg
     6721 ccagaattga aaaaaacact tggcgaagaa ttgcttgagc caacgaaaat ctatgtttct
     6781 tccttgcttc cgctgatcaa agaaaagaaa ataaaaggag ctgcacatat cactggtgga
     6841 gggtttgtag aaaatatccc gcgaatgtta ccagaatcta tggctgcaca aatcaaactt
     6901 ggctcatggc cgattcttcc aatattcggc tgtttacaaa aatatggtga aattcctgag
     6961 atggagatgt atgaaatctt caatatgggc atcggtatgg tcctggcagt cgaagaatcg
     7021 aaagtaaaag aaatagtaca cgaaattgag caagctggcg aaaaagttta tgaaatcggg
     7081 aaagtgatcg ccaaagaaaa acatcgtgtg gtgtttatag gagaagaacg atgagaatcg
     7141 ctgtttttgc ttctggaaac ggaagcaact ttcaagcgct agccgattat ctatcgaaaa
     7201 aaggattgga atcttcgatt gactggttgt tttgtgatca gcctgaagca tatgttttga
     7261 aacgtgcaac tgcgttgagt gtaccggcag attgtttttc acctaaagaa tttgattcaa
     7321 aaaaagagta tgaagaagca attttgcata aattgaaaga aaaaaagatc gatttgatcg
     7381 tattagctgg atatatgcga atcattggac cggtattgct gaaaaattat gataaaagaa
     7441 tcatcaatat ccatccgtct cttttacctg ccttccctgg tttgcatggc atacgtgatg
     7501 cctttgaagc tggagtaaaa gaaacgggtg tcacaattca ttatatcgac caaggtgtag
     7561 atactggacc aatcatccgg caggaaaaag tgagaattga acaggaggac acgttcgatt
     7621 ctttagaaga aaaaatccat agagtagagc atcgaatcta tccagaagtg attagtgaaa
     7681 ttattgaaaa tggaggctat ctgaaatgac aagagcattg atcagtgtat cagataaaac
     7741 tgggattgta gcattcgccc aaggtttgat tgaacaagga gtagaaatca tttcaacagg
     7801 aggaacaaag catgcgttgg ataaagctgg gatcaaaacg ctttcgatcg aagaagtgac
     7861 agggtttcct gaaatgatgg atggccgtgt caaaacactt catcctaaaa tccatggtgg
     7921 tcttttagga agacgcgatc tccctagcca tatggaggca atggaaacgg aaaatatcca
     7981 accaatcgac tttgtttgtg tcaatttata tcctttcaaa gaaacgatta tgaaaccaga
     8041 tgtcgaaata gcagaagcta ttgaaaacat tgatatcggt ggtcctagta tgctccgtag
     8101 tgcagcaaaa aaccatgaat ttgtcacctc tgttgttgat ccatctgact atgaagaagt
     8161 actttcagaa ttacgtcagt atgggcatac ttcactttct ttcagacaaa aactagcggc
     8221 aaaagtcttt cgtcatactg cggcatatga tgcactgatc gctcaatact taacggattg
     8281 ggtggaagaa aaagaaccgg aaaaattgac acttacgtat gaacgaaaac aaacgcttcg
     8341 ttacggtgaa aatagccatc aagccgctgc cttttatcag tccgctcttc tggaaaaata
     8401 ttcgatcgca gcagcaaaac aactccatgg gaaagaactt tcttataata atatccgaga
     8461 tgcagatgct gcgctacgga tcatgaagga atatgacgag ccaacggtag tcgccttgaa
     8521 acacatgaat ccttgtggta ttgggacagc atctacgatt ttagaagcgt gggaagcagc
     8581 gtatgaagca gatcctgttt caatctttgg tgggatcatc gttttgaatc gagaagtaga
     8641 tctgccaaca gcagaacaga tgcataagct gtttctagaa atcatcattg ccccttctta
     8701 tacacaagaa gctttggaat tactgcaaaa aaagaaaaac atccgattac tgacagtaga
     8761 ctttgcgcag gaagaaaatc aaaatcgaga agaaacggtc tcagtcttag gtggacttct
     8821 tgtacaagat caagatctgg caatagaaaa tgaagaagag tggaaagtcg tgacaaaacg
     8881 taagccgact ccagcagaag caaaagcatt agtgtttgct tggagagctg tcaaacatgt
     8941 gaaatctaat gcgatcgtac tggcaaacga acgtcagaca gtaggaatcg gagccgggca
     9001 gatgaatcga gtcggttcag taaaaattgc gattgaacaa gcgcaagaga aaatggaagg
     9061 tgcagtttta gctagcgatg cttattttcc aatggatgat tcggttgaat atgcagccaa
     9121 acatggtata aaagcaatca ttcagccagg aggaagcatc aaagaccaag attctattga
     9181 tatggcgaat aaatacgatc tagcaatggt ctttactgat gttcggcatt ttagacatta
     9241 gagaggagtc ggataaatga acattttggt gatcggtgca ggtggtcgtg aacatgcaat
     9301 aagtaaaaaa cttttagcca gtccgaaggt ggatacggtg tattgtgcgc caggaaatcc
     9361 ggggatgaca aaagatggta tcaattgtgt cgctatcagt gagcgagatc attcagcgtt
     9421 aatccatttt gttaagaaag aggctattga ttggagtatc gttggtcctg aagttccttt
     9481 gttaaatggg atcgtcgatg attttatggc ggaaggattg aaaatcttcg gtccgacaaa
     9541 agcagcagct ctgatcgaag gttcgaaaag ttttgctaaa caattaatgg atacttatca
     9601 aatcccgaca gctaaatcca gaagttttga atgttacgaa aaagcagcag cgtatatcaa
     9661 agaaaatggt gcgccaatcg tagtgaaagc ggacggctta gcagctggga aaggtgtagt
     9721 cgtggctacc acagtgaagg aagcgctgga tgcggcagaa caaatgttga accagcatcg
     9781 atttggggat agtagcaaaa aaatcgtcgt agaagagttt ttggcaggag aagaattctc
     9841 ccttttggcg tttgtccgta ataccaaggt gtatccgatg gtcatttcgc aagatcataa
     9901 gcgggcattt gataacgata aagggccaaa tacaggcgga atgggtgctt attcaccagt
     9961 accgcaaatt tcaaaaaaga tgattgaaaa agctgtggaa gaagttttaa aaccagcggc
    10021 tttgggaatg aaagaactag gacgctcttt cacgggtgtt ttatatgcgg gtttgattgc
    10081 tacgaaggaa ggaccaaaag tgatcgaatt caatgcgcgt ttcggtgatc ctgaaacgca
    10141 agtcgttctt tctcggttga agagtgactt tgcgcaagta atcgatgatt tattagagaa
    10201 tcgtacagta gagttaaagt ggcagcaaga aggatacaat gtaggcgttg tggttgcagc
    10261 tgccggttac cccgaagaat atgagacagg aatggttcta ccagattttc tggaagaaga
    10321 gctttctgtt tactatgctg gagtttcctc aaataacggc aaactagttg gagcaggagg
    10381 acgtctttat ttagtagaag catacggtga gacgatcaaa gaagcacaga aaaaaattta
    10441 caccgcgtta atggataaaa cgacagatgg aacattttat cgtacagata ttggagaaaa
    10501 agctgccaat agcgaactga tcgtgaagta aatcagctgc ttccatttat aaaaaataca
    10561 acaaacataa tcggaagcgc cgattttagt gaagcctttt cataaagagt gtggtacact
    10621 tttgttgtgt atataaataa ggaggagttc agatgaaaaa aattcaatta ggtacttctg
    10681 atcagaaagc agctgcagtg atcttaggct gtatgcgtat caacaatgcg gaagatccag
    10741 taaaagtgat tgagacagct tatgaaaacg gcattgattt ttttgaccat gcagatattt
    10801 atggaaacgg tgaatgtgaa gaaatctttg cagatgctct agcaaaaaca tcaatcaaac
    10861 gagaagatct ttttattcaa acaaaatgtg gaatcgttcc aggtgtgatg tttgattttt
    10921 ctaaaaaaca tatcattgaa tctgtagaaa aaagtttgac ccgtctgaaa atggattatg
    10981 tggatgcttt acttcttcat cgtccagata cattggtaga accagaggaa gtagctgaag
    11041 cgtttgatga attggaacgg tcaggaaaag ttcgttattt tggcgtcagc aatcaaaaac
    11101 caatgcaaat cgaattgctg aaaaaatatg ttcgtcaacc attagtagct aatcagctgc
    11161 aatttggctt gaaacatact ggaatgatcg atcaagggat tcatgtcaat atgacagatg
    11221 aagcaagtat cgatcatgac ggtagtgtac ttgattattc ccgattgcat gatatgacga
    11281 tccaagcatg gtcaccatac cagtatggat tttttgaagg tgtatttatc gggaacgaaa
    11341 aattccctga attaaaccaa acattagaag aactagcagc taaatatcaa acgacaccaa
    11401 ctggcttggc ttctgcttgg attttacgcc atccagccaa tatgcaagtg atcgccggta
    11461 cgatgaacgt agggcgaatc aaggaaatcg ctcaagcttc agaaattaat atgtctcggg
    11521 aagattggta cgaattgtac cgtgctgctg gaaacatttt accttaaaga ttgtcataag
    11581 caggtcaaaa gggctataaa ttaaaaagac agaataactt gaaagctgtt ttcagcttcg
    11641 agatattctg tcttttttta ttgcaaatgg aaagagtatc attgtacgga tttcgtttat
    11701 tagttatttt tgtttttaag gaaaagctgt gtccgatatt cttttggaga aatcccttgt
    11761 tttttcttaa ataaataact gaaatagtta gggtcattat aaccaatttc aaaagcaata
    11821 tctgaaatac gatagtctga ttgctgcaat aatttttttg ctaattcgat tctttgttct
    11881 gtcagataat cgatgaatgt ttggttaaac gattgagaaa aaatcgtact gaaatgagag
    11941 ggacttaatg caacttgttg agcgacccaa gttaaggaca tatctggatc ggtaaaattt
    12001 tctttgataa aatccaatgc atggttcaaa attggctgat atttgttcct tgaaggctgt
    12061 gagggcagag cagttaagaa agaaatgaac atataaactg tcgaacggta aagcgagtcg
    12121 tcggcgctga ttgctaagcg ttgactggtg gatgtgcaat gaaccatttc ttgcgggatt
    12181 ttcttttctt tcaggcagac atgctggagt agcttagtca agacaaataa acgatataat
    12241 cgtgttcgag ttggtgtgcc ttgtggtttc gtcaagtgtt cgatgtactt agatacttcg
    12301 tttttcgata atgaagacaa atcaagtgag aggtcaaagt aaaagacaga atcaactgga
    12361 agtttcgctt cttgaatcaa atcctcatag ctgataattt gttctttaag ggaactggcg
    12421 gtttcaagta tcatctgcgt gatctcaaaa gatgcaggta attcgctgat tctttctgcg
    12481 acaggaccaa tggcgacaga aaaattattt ttttgtccct tttctaattc atggaccaac
    12541 gtttgggcta cctgataact ggtctcgatc acattttctt caagagaatc aactattaaa
    12601 aatttgatga atcgagagga aacagcagag aagatcactt gttgattctc cctaaataaa
    12661 aacttcaaat aatcactgag atgagcgtaa tcttcaaagt ctgtactgac ttggtttgct
    12721 gctaataata cggtcatttt tttccctgct aaagagcgat tgaaagattc agcaagtttc
    12781 aatgtttcac tgatcgtaag tgagcctttg aacaaaccgt tcaagaaatg attttttttc
    12841 aattcgaaaa caagatcaga agaagtgtgc gtttcttttt gctgcaaatc taaagcagtt
    12901 actgcttttt ctattgcttg tttcaattcg ctacttttaa tcggtttaag cagataatca
    12961 tctgcctgta cctggattgc tcctttcata taatcgaaat cgtcgaatcc actaataaat
    13021 atgagacgag tccaaggaag tagtttcctt gcttcttttg aaaaagtcaa cccgtccatg
    13081 aaaggcattt ggatatcagt cagaatgatg tcgggctgta agtcgataat tgaagacagt
    13141 gccatctcac catctccagc ttcgccgaca taagtgattg gataataaga accaaggaca
    13201 gttatttgtt cccgcaagtt attgcgaatg aggtattcgt cttcgatgat aaaaacttta
    13261 tacatgtttg tttcctccaa ttgttttggg agatagaggg atcatcagtg tgacagttgt
    13321 tccttctcgg tatttgctgt caatcgtgat aggtttttga tcatttccgt aataaagaag
    13381 gagacgcttg tttacgttgt aaagtccgta gccgatactg aaatctgaat cgatcccttt
    13441 ggctaactct ttacgtattt ctgccagttt ttctgcaggg atgccaatcc cgttgtctat
    13501 aactttgaat tggatcatct catcaatttt gcatgtggta atacgaataa atcctttgtg
    13561 acggacgtac ttcgttccat ggtatacagc attttcaatc aatggctgca agatcatttt
    13621 taaaatagaa acaggaaaaa gtgtttctgg tatatcgatc ttatagtcaa gcatatggcc
    13681 gtatcttatt tttaagatga ctagataatc attgatatgg ctaatttctt tttcaagagg
    13741 aatccagtct tgtcctttgc ttaaagacgt acgaaaaaag ccggaaagtg catgggtcat
    13801 agtcagagct tcttcaaagc agtcttgttc gatcaaagaa ataatggcat ccaaactgtt
    13861 ataaataaaa tggggagtaa tctgagcttg caatacacga acttcacttt gtgctaaatg
    13921 gtattgtttc aaagcgttct cccgtaaaga ctggtttaga tcttccgcca ttttattcat
    13981 gctagcggta agtgtttgta attccagtgt ttccggcagg gttaaacgaa agccaaggtt
    14041 ccctgaagaa agttgttctg acatctcgat cagctgattg atcggttctt ggacctttct
    14101 ctctaaaaag cgacgattct ttttcgcata gaaaaaaatg gtactaagaa ctccaagttc
    14161 cactattgtt aatagaatga gcgagcggac aagtgtcgta ttttttttgc ttgctaagtc
    14221 gatctccaca cgaacaaaat cttgtaagat atctgacagc agttgagtga cagaatctac
    14281 ctgattgatg atctcttcat tggtatccat aaaatctttt gccaagatat tattgatcag
    14341 ctcgttttga taatcttcca gtgtatcgat cgtacgtagc gatacatcta acgtactaat
    14401 ttctttaagt gtatttgtat tatttttgat ctctcgaata tcattcctaa gttcttctag
    14461 gatattttcc tcattgaact catctacggt tacttggcca gaaatcaagt cccacatact
    14521 ttccaaaact ttttgatcaa ccttcaaagc aattgcatct gctttttgga tatttgcgat
    14581 cgtctgttga taaatcaaaa gctgttgcga atataacagt atgctcagta gcaaagggat
    14641 aacagcaaat agaagcatgg ctttgtttgc ttgggcaaaa atctgtttta tgcttaaatt
    14701 ttttgtcatg atacttctcc agtcaataat ttctggttgg gatgttagct atattctgct
    14761 gggaaaagac agtctcggaa ataaaaatat ctttaggtaa tgtttttcct gtttgaatat
    14821 ttccaaaata acgagtaacg gtattggcta cataccagcc gacatcaggt ttacactcga
    14881 ctacacaatt gacgattcct gagcgtagct tctcgatcat atcttcttgt ccatcaatag
    14941 ttacaatgat caaatcttct ccaggtttga ttgatgtttc ttttatcgca gctaaagcac
    15001 cgtgagtcat ttcatcacta tggctgtata atacatcgat ttcggataaa tcatttgttt
    15061 ctaaatatcg tttcatctgg tcttttcctt tcatccgaat aaaatcaccg acaattcggt
    15121 gaacaatagt catcggaggt ttatggtcga tggttccatc tttttttagg gttggtttac
    15181 gattgattga ttccaaaaat ccttcggagc gtagcttggt cggtgtggag ttctctgaac
    15241 cagcaagttc taggattctg atttcctgtt tctttgaatt tgtgaagtga ttgctgacaa
    15301 ataaacccgc ccgatttcct tctgctttga aactggggcc aatgtgggtg acgaaaagct
    15361 cgggatcatt cgtttgaata tgtctgtcga caagtatgac agggatccct gctcgctttg
    15421 cttcttttaa tacagagtcc cacccggatt cttgcaaagg agtaaaaatg atcatatcca
    15481 ctttataggc aatgaacgtc cgtatatctt ggatttgccg ttcctgattc atgtagccat
    15541 ttcggtagag aacttggtaa tcttcttttt caagcgcagt gataattgat tcagtatgct
    15601 ttttccgcca gctactctcc gttcctgatt gcgaaaaacc aacgactagt gggtcaggtg
    15661 cttcctttgt attaggtgta caccccatca tttggtaagc gattacaaca agggctaaaa
    15721 aaaataaaac acgtttcact ttaaatcact ccatctggat ttgttagtac tatcttatca
    15781 gataaaaggg aaaatcaaag tcaaaaggaa tcaatcgaaa aaaatccaag aaacttaaaa
    15841 aaatccaaga caaaaaaagt acacctaaaa aatttaaagt aaatcccata aaaaaatcaa
    15901 tgttaacgct ttctttatta gctatactcg gtgtatcaat tgaaatgggg gataaaaaat
    15961 gaaaaacaaa tttagaaaga ttgttgggac tatcgctatt ttgaccgcaa gcattctatt
    16021 aagtgcgtgt ggcaattcag gatctgcaga tgatagtacg gggtatgtag gaatcgctat
    16081 gccgaccaaa tcagcagaaa gatggatcgc tgatgggaac aacatggtct cggaattaga
    16141 aaaactgggt tataaaacag atcttcaata tggagaagat aaagtagaaa atcaagtagc
    16201 acaaatagaa aatatgatta caaaaggggt agatacactt gtgattgctt ctatcgatgg
    16261 ttcggcttta actgatgtgt tagctaaagc aaaagaagca gatatcaagg tgatcgccta
    16321 tgatcgttta ctgatgaatt cagaaaatgt cgattattac gcgacttttg ataattttgg
    16381 agtaggtgta tcgcaagcag cttatattga agagcactta ggattgaaag aaggaaaagg
    16441 accattcacg attgaattat ttggtggctc gcctgacgac aacaacgcac taatcaatta
    16501 caacggagtg atgtctgttt tacaaccata tatggacaac ggtcagttgg tcgtgccatc
    16561 tggacagacg agtttcagtc aaatcgctac gcttcgctgg gatggttcta cggcgcaagc
    16621 aaggatggat aatctgttaa gcgcaaatta tactgaccaa acattggatg ctgttttgtc
    16681 gccatatgat ccaataagtt taggaatcat ttcgtcatta aaaggcgtgg ggtatgggag
    16741 tgaaagtaaa cctttacctg tgattactgg acaagatgcg acagttgctg gcgttaaatc
    16801 gatcattgcc ggggaacaaa cacaaacgat ctttaaagac acacgtatct tagcaaaaaa
    16861 tacgattgaa atgatcaaag caatcagtga tggagaagag gttccggtca atgatactga
    16921 aacttatgat aatggggtga aaactgtccc tacgtattta gcaaatacag tatctgtcga
    16981 taaagataat tatcaagcag agctgatcga caccgattat tataaagaat ccgatctgaa
    17041 aaattaagag gaaccaaaca aggaactaaa gagatctaag tcagagagag gataagaatt
    17101 atggcggatt gtattttaaa aatggcagat atcaccaaaa aattttctgg aatccgagcg
    17161 ttagattgcg tgaatctgat gattgaacgt ggggaaatcc atgcattgtg cggagaaaac
    17221 ggagcgggaa aatcaacatt gatgaatgtc ttgagcggct tgtatccata tggctcctat
    17281 gacggggaaa tcttttatga tggaaagctg tgtcaattta aagatttgaa agatagtgaa
    17341 gaaaaaggca tcgtcatcat tcatcaagaa ttagcactaa gtccttatct ttcaataaaa
    17401 gagaatattt ttctcggaaa tgaacaagca gaaagaggcg tgattgattg ggaactgaca
    17461 gaaaagaaaa catatgaact gctgaataaa gtcggtttgt ctatcgaccc gaatcttcta
    17521 gtatcccaga ttggcgtagg gcaacagcaa ctagttgaaa tagctaaagc attatcaaaa
    17581 tccgtccgtc tgttgatttt ggatgagcct accgctgcat tgaatgaaga agaaagcgcg
    17641 aatttgctga gattgatccg agagttgaaa gagcaaggtg taacctccat cattatttca
    17701 cataagctga atgaaatcgt ggatatcgca gatcgaatca ccattttacg ggatggacag
    17761 acgattgaga cactagaaaa tgaaatgatc agcgaagagc atattattcg cggaatggtg
    17821 ggcagagatt tagttgatcg ttatcctgaa agaaaaccgg atattggaga agtttatttt
    17881 aaagtagaag actggacggt ctatcaccct cttgatcacg agcgaatcat aaacgaccac
    17941 atcaacttgc atttgaaaaa aggagagatt gtaggaatag ctggactgat gggagcgggc
    18001 agaactgaat tcgctatgag tctatttgga cattcttatg gaagcaagat atccggacgt
    18061 atattaaagg aaggggcaga gatatcagtt aagaccgttc cttcagccat tgcaaacgga
    18121 ctcgcttatg tctcggagga ccgaaaatct ttaggactga atctgctgat ggatattcgg
    18181 gaaaacgtga cgctgagcag tttggataaa ataagtcaaa aaggagtatt agataaagaa
    18241 aaagaagtaa ctgaggcaga aaatttccgg aaaaagatgc gtataaaaac aaactccatc
    18301 catcaaattg tcagtagtct tagtggtggg aatcaacaaa aagtcgtttt atccaagtgg
    18361 ctgatgacac aacccgatat tctttttttg gatgagccaa cccgtgggat agatgttggg
    18421 gcaaaatatg agatctacac gattatcgaa gaaatggcag caaatggcaa agctgtctgt
    18481 cttatctctt ctgaacttcc tgaaatatta gggatgtgtg atcgaatcta tacgatgaac
    18541 gaaggacgta ttacaggaga agtctcgcga gaagatgcag atcaggaagt cttgatgaaa
    18601 ttaatgacga aagaagaggt gggttaagtt ggaacaggca aaaaatctta cggataaaaa
    18661 agagaaaaaa ctaaatttga aaagtagagc agctgatctt tttggtcgct acagcatggt
    18721 gatcatttta gcgggactac ttattgcgtt tcaattgatg acggatggta ttttctggcg
    18781 tccattgaat ataactaacc ttgttctgca aaatagccat atattagtac tagctgcagg
    18841 gatgttatta gttgtgctct taggtcatgt ggatttgtcg gtagggtcag tgatggcgtt
    18901 tgttggtgca attgcgggca tgatgatggt caatcgccaa atgaacccgt ggatgacagt
    18961 tatcgcatgt cttgcagtag gcgggctgat cggcgcatgg caaggttttt gggtagctta
    19021 tgcagggata ccggcgttta tcgtgacttt agcaggattg ctgatgtttc gtggactgac
    19081 acaagttgtt ctaggaggcc aatctctagc accttttcca gctgttttcc aaaaaatgtc
    19141 tacgggttat ttaccagact taagcgaagg aagcagcctt cacttcttga cattgatttt
    19201 aggaatgatc atcacgatcg tgttagttgt tggtcaatgg cgaacaagaa atcgtcggaa
    19261 aaatcattta tttgaagtgg aatctccaac agctttcttg gtaaaggcgg tatttacagc
    19321 agtcgttgta ctaggaataa cttatatctt tgcctcttat caagggtatc cgattatttt
    19381 gatcattctt ggtttgatcg ttgcagcata tgggtttttg acaaataaaa cagtagcagg
    19441 tcgacagatt tatgcgacgg gcggaaatcg aaaagcggct gaactatcag ggatcaaaac
    19501 aaagcgaatc acgttctggg tattcgtcaa catgggagtc atggcagctt tagctggatt
    19561 agttttagct gctcgattga atgcggcaac acctcaagca ggtacatcga tggaactgga
    19621 tgcaatggcg gcagtatatt ttggtggtgc ttcgacttcc ggcggcattg gaacaatcat
    19681 gggtgcgatt gtcggtggct tggtcatggg tgtattgaac aatggcatgt cgattttagg
    19741 cgtcggggta gactggcagc aggcaatcaa aggattgatc ttgcttttag ccgttgtgct
    19801 agacttgtat aataagaaaa aacgaacaac gtaggagaac gccggttatt cagaaaaaag
    19861 actgtgacaa gacatttgtc acagtctttt tttcgctaaa agcgaacatt cattgtttcg
    19921 tttgtataga ctaaaaataa tatatgtttt tttaccattc gtataaattc tctttttgct
    19981 cttgattttt ttgcttaatt gagttaaatt acatagggcg ctaaaaaaag ccttgattaa
    20041 attaataatg ttcgtgtttt gctggatgtg aacatcagga ggataatgta atgaaagtat
    20101 ttgattacga agatattcaa ttaattccta ataaatgtat cgtaaatagc cgttctgaat
    20161 gtgatacaac ggtcacatta ggtaaacata cattcaaaat gccagtagtg cctgccaaca
    20221 tgcagacgat tattgatgaa acaatcgcag aattcttagc ggaaaatggt tatttctata
    20281 tcatgcatcg gtttgatgaa gcagctcgaa ttccgtttat caaaaaaatg aaaaagcgtg
    20341 gattgattac ctcgatcagt gttggcgtca agaaagagga atattccttt atagagaagt
    20401 tggcagaaga atcgctaaat cctgattata tcactatcga catcgcgcat ggacatgcta
    20461 actcagttat tgatatgatt cagcatatta aaaaatattt gcctgaaact tttgtgattg
    20521 ccggtaatgt tggtacaccg gaagccgtcc gtgaattgga aaatgcgggc gcagatgcaa
    20581 caaaagtcgg gattggtcca ggaaaagtat gtattacaaa aatcaagaca ggctttggga
    20641 ctggaggctg gcaactggca gctcttagat ggtgtgcgaa agcagctcgc aagccgatca
    20701 tcgctgacgg tgggatcaga acacatggcg atattgcaaa atctgtccgt tttggtgcga
    20761 caatggtcat gattggttca ttgtttgccg gtcacgagga atctcctggc gaaacaaaag
    20821 tcgaaaatgg aatcgtgtat aaagaatact ttggttctgc ttcagaattc caaaaaggcg
    20881 aaaaacgaaa tgttgaagga aagaaaatct ggatccaaca caaaggatct ttgaaagata
    20941 cactagtgga aatgcaacaa gaccttcaat catctatttc ttatgctgga ggaagagatc
    21001 tggaagccat tcgaaaagtt gactatgtca tcgtgaaaaa ttcgattttt aatggagaca
    21061 caatctaaaa aataaataaa atattaggat gttgtgaaaa agttgtcctg cattaagtaa
    21121 taagaacagc caaacaaaaa tagttcttta tatgttttgt ttggctggaa ttattatcgc
    21181 agatacaagc ttttgaacat cattattcag aataagggac tgtgataaga tttttgtcac
    21241 agtcccttat gttttgcaaa aaaagttttt cttttttctc gtaaattcgg taaaatcaaa
    21301 agaaaaaata gacaatagaa aagagaagct tatgtgggaa aaagtagaga aaaaacaagg
    21361 accgatttat cgtcaaatta tggaacagat tatgagagaa atcgaaaacg gaaggatcaa
    21421 tcctggaagt caacttgaat cagaacgaaa actagggcaa ctttttggtg tgaatcgttc
    21481 caccgttgtc catgcattgg aagagcttag ggagcttggg gtactaacga gcaaacgtgg
    21541 cagcggatgg tttgttaatc agactgaatg ggggaaattc gctgttccaa gaatcgattg
    21601 gcggcaaatg atctctcctc gttatgagca gacggactgg tatgagcaaa aaataagaga
    21661 agcaaagcag atccaaaaaa catcgtttct tgatttatac gctagcgaga tgccagatga
    21721 gcttttgccg aattttgagt ttccttctta ttctcttgaa gaaatcttag cggaagaaaa
    21781 agaaatggat cttttaggct atactccgtt acgtaacaaa atcaaacggt atttggaaag
    21841 taaatttgaa ttggcatttt cccccaacca gcttcttgtg actggtggcg gtcagcaagc
    21901 aatctttttg attttacaaa cgattctttc agctggagag gggatagctg tagagtcacc
    21961 ttcttttttt taccgattac ctcttttcaa agcttcagga acgcgtttat ttgggatacc
    22021 gatggatgaa gaagggatcg acttagaaaa actgaaagaa tcgatccata aaaataaatt
    22081 gaaagcagtg cttatcaacc cgaattttca aaaccctaca ggaaaagtga tgagtcaaaa
    22141 acgacgagaa aagctagtag aattgtgtcg acagtatcgg cttccaatta ttgaagacga
    22201 tgtatttacg gatctttcat ttctaaacca agaagaagtc cttcctatac gaacgattga
    22261 tccggataat gtgttatacg tcggttcgtt atctagggtt ttaggaaaaa caacgaaaat
    22321 cggttgggtg ataggacctg agacttttat ctcgcaacta gctcaagcgc aagaaatgat
    22381 ggagttttcg atgaatatcc ttacacaaat cacagtggct aatgtattta atgaagcaat
    22441 tgatttgaaa atgcaagatg taagaaaaaa gttgaaagaa aaaagccgac tgataagcgc
    22501 ttggggagat tcacaatcgt ttttcaagct tcattcaatt ttaggtggtt actatgcctg
    22561 gattacttgg gatgggaaaa aactagaccc cgaactagca gaaaaagtag tagatatggg
    22621 tcttggaatt gcaccaagtc tactttttgg gcaagatata aatggaatca gaatcaatta
    22681 cagtaggctg gatgaaaacc aaataccgtt gttttattca aagatgaaaa ttctagaaaa
    22741 gtggttaaca gaataatttc acaaagtaaa tagattaaag aatataacag cttggattta
    22801 aatttcaagc tgtttctttt ttttcggaaa aagaatacga tataaagaaa ctaagaaaaa
    22861 accattattt gtacgtccgt tcacgatgtg taaataaaat aaatgtttgc aacaaaactg
    22921 tataacacca acgtttttaa atagaaacag atggttgtaa gtttgattag aaaatagaaa
    22981 aaatgcagat gaaatataaa acgctttcct tattgtgatt ttattcacta atgctgttaa
    23041 tatgcggatt ggcataattt cctttcatcg tgaaaatttg tgcttttagc ttgtatttct
    23101 cataaatcca tgataattta ttaatgaaga cggttaaata gtgatacagt tttattcact
    23161 gtttcaatcg cagaatgaag agattttctt atagatgaga gaggaatgtg tgacaaatgg
    23221 caaacaaaaa agcaccgatc gacttccaag cactgctaga tgaagtcaat gcagatttcc
    23281 cagtatatca agcacttgat caagatggaa acgtagttaa caaagattta gtacctgatt
    23341 tatccgatga tgaactcgtt gaattaatga ctcatatggt atggtctcgt gtattagacc
    23401 aacgttcaac agcgctgaac cgccaaggac gcctaggctt ttttgcacca actgctggac
    23461 aagaggcaag tcagctggct agtgcttacg catttgataa agaagatgtt cttcttccag
    23521 gttatcggga tgtacctcaa ctagtaaaac atggtttacc tttatctcaa gcttttttat
    23581 ggtctcgagg acatgctgca ggtaattctt atccggaaga attgaaagct ctaccaccac
    23641 aaattatcat cggtgcacaa tatgtacaag cagccggtgt tgcattaggt ttgaagaaac
    23701 gaaacaagaa aaatgtcgtc ttcacttata ctggtgatgg cggttcatca caaggtgatt
    23761 tttacgaagc aatcaatttc gctggcgctt accatgcaaa tgccgtattt tatatccaaa
    23821 acaacgggta tgcgatctct acacctcgtg aaaaacaaac tgcagcaaaa acacttgcac
    23881 aaaaagctgt cgcagctggg attcctggta ttcaagtcga tggaatggat ccgcttgcag
    23941 tatatactgt atctaaaatg gcacgggaat gggcgatcag tggaaatgga ccagtcctaa
    24001 tcgaaacact gacttatcgt tatggaccac atacactatc tggtgacgat ccaacccgct
    24061 accgtacaaa agacacagat gacgattggc agaaaaaaga tccattgatc cgcttccgta
    24121 aatatttgac ggaaaaagga ctttggtctg aagaaaaaga agaacaagtc atcgaagcaa
    24181 ctaaagaaga aatcaaagca gctattgctg aagccgacaa agtaccaaaa caaaaggttt
    24241 cagatttctt gaaaaacatg ttcgaagtat ctccacaatc aatcaaagaa caaattgcaa
    24301 tttatgaagc gaaggagtcg aaataatcat ggcacaaaaa acaatgatcc aagcaatcac
    24361 agatgcctta gcacttgaac tagaaaatga cgagaatgtc gttgtttttg gtgaagatgt
    24421 tgggaaaaac ggaggagttt tccgggcaac tgaaggattg caggaaaagt tcggagaaga
    24481 ccgagtattc gatactcctt tagctgaatc tggaatcgca ggattgagtt tcggtcttgc
    24541 gttagaagga tttcgtccag ttcctgaaat ccaattcttt ggttttattt tcgaagcaat
    24601 ggacgaagta gtagctcaaa tggctcgtac aagatatcga atgagcggca ctagaaatct
    24661 acccatcaca attcgttcgc catttggtgg cggtgttcat acaccagaat tgcattcgga
    24721 taatttagaa ggtttgatcg ctcagtctcc tggtattcga gtagtgattc cttccaaccc
    24781 ttatgatgca aaaggactat tgatttcttc tattagaagt aacgatccgg ttgttttcct
    24841 agaacacatg aaactatatc gctcattccg agaagaagtg ccggatgaag cttacgaagt
    24901 tcctttggat aaagcagcag ttactcgtga gggaacagat gtatctatta tcacatacgg
    24961 agcaatggtg cgtgaagcaa tcaaagcagc agacaatctt gcaaaagaaa atatatctgt
    25021 tgaaatcatt gatcttcgta cagttgcgcc attagatgta gaaacgatca ttcaatccgt
    25081 ggaaaaaact ggtcgcgtag ttgttgtcca agaagcacaa cgacaagcgg gcgttgccgc
    25141 gcaagtagtt tctgagatct cagaacgcgc tatcctttca ttagaagccc caatcggacg
    25201 agtttctgca cctgatacag tcttcccatt tggacaagca gaaaatgtct ggttgccaaa
    25261 tgcaaaagat atcgaagaca aagtaaaaga aatcgcggaa ttttaagaaa agaagggacg
    25321 aaacaaagtc atggcttatc aatttaaatt gccggatatc ggtgaaggaa tcgc
//
LOCUS       DAFBSV010000039        23819 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.040, whole genome shotgun sequence.
ACCESSION   DAFBSV010000039 DAFBSV010000000
VERSION     DAFBSV010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23819
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.040"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(45..779)
                     /locus_tag="LLB18_001453"
     CDS             complement(45..779)
                     /locus_tag="LLB18_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBK5244460.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1106..1516
                     /locus_tag="LLB18_001454"
     CDS             1106..1516
                     /locus_tag="LLB18_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBK5244461.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1509..2210
                     /locus_tag="LLB18_001455"
     CDS             1509..2210
                     /locus_tag="LLB18_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBK5244462.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2210..3796
                     /locus_tag="LLB18_001456"
     CDS             2210..3796
                     /locus_tag="LLB18_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5244463.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3815..4036
                     /locus_tag="LLB18_001457"
     CDS             3815..4036
                     /locus_tag="LLB18_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HBK5244464.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4033..4794
                     /locus_tag="LLB18_001458"
     CDS             4033..4794
                     /locus_tag="LLB18_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HBK5244465.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5174..5683
                     /locus_tag="LLB18_001459"
     CDS             5174..5683
                     /locus_tag="LLB18_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBK5244466.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5758..6297)
                     /locus_tag="LLB18_001460"
     CDS             complement(5758..6297)
                     /locus_tag="LLB18_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBK5244467.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6437..7048)
                     /gene="rpsD"
                     /locus_tag="LLB18_001461"
     CDS             complement(6437..7048)
                     /gene="rpsD"
                     /locus_tag="LLB18_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBK5244468.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7310..8161
                     /locus_tag="LLB18_001462"
     CDS             7310..8161
                     /locus_tag="LLB18_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBK5244469.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8189..8824
                     /locus_tag="LLB18_001463"
     CDS             8189..8824
                     /locus_tag="LLB18_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBK5244470.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8844..9617
                     /locus_tag="LLB18_001464"
     CDS             8844..9617
                     /locus_tag="LLB18_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBK5244471.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10025..10822
                     /locus_tag="LLB18_001465"
     CDS             10025..10822
                     /locus_tag="LLB18_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HBK5244472.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10800..11213
                     /locus_tag="LLB18_001466"
     CDS             10800..11213
                     /locus_tag="LLB18_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBK5244473.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11197..13842
                     /gene="mutS"
                     /locus_tag="LLB18_001467"
     CDS             11197..13842
                     /gene="mutS"
                     /locus_tag="LLB18_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBK5244474.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13860..15968
                     /gene="mutL"
                     /locus_tag="LLB18_001468"
     CDS             13860..15968
                     /gene="mutL"
                     /locus_tag="LLB18_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBK5244475.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15990..16550
                     /gene="maf"
                     /locus_tag="LLB18_001469"
     CDS             15990..16550
                     /gene="maf"
                     /locus_tag="LLB18_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBK5244476.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16635..18623)
                     /gene="treP"
                     /locus_tag="LLB18_001470"
     CDS             complement(16635..18623)
                     /gene="treP"
                     /locus_tag="LLB18_001470"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HBK5244477.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18846..19559
                     /gene="treR"
                     /locus_tag="LLB18_001471"
     CDS             18846..19559
                     /gene="treR"
                     /locus_tag="LLB18_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HBK5244478.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19636..20082
                     /gene="msrB"
                     /locus_tag="LLB18_001472"
     CDS             19636..20082
                     /gene="msrB"
                     /locus_tag="LLB18_001472"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HBK5244479.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20252..20854
                     /gene="ruvA"
                     /locus_tag="LLB18_001473"
     CDS             20252..20854
                     /gene="ruvA"
                     /locus_tag="LLB18_001473"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBK5244480.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20867..21868
                     /gene="ruvB"
                     /locus_tag="LLB18_001474"
     CDS             20867..21868
                     /gene="ruvB"
                     /locus_tag="LLB18_001474"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBK5244481.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21897..22475
                     /locus_tag="LLB18_001475"
     CDS             21897..22475
                     /locus_tag="LLB18_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK5244482.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22527..23009
                     /locus_tag="LLB18_001476"
     CDS             22527..23009
                     /locus_tag="LLB18_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HBK5244483.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23126..23500
                     /locus_tag="LLB18_001477"
     CDS             23126..23500
                     /locus_tag="LLB18_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244484.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7774 a         4285 c         5115 g         6645 t
ORIGIN      
        1 ttggtacgca atcgctgtac caagtttttt tatttagctt ttgattaagc cataaataat
       61 aatttatata agaatactgc tacgacacca gcacagatag gtgctacaac tggtacccat
      121 gcatatcccc attgagaaga acctttatgt ttcaatggaa gaagtgcgtg tacaagacgt
      181 ggagcaaagt cgcgggctgg gtttagtcca ggacctgtag gaccaccaag tgaagcaact
      241 aatgtccata caaggaaacc aagtgctaag tgagctgtac caagattatc ttggaagaat
      301 ggtgcttttg taatacctag ggcaccaaag aataaaacga atgaaccaaa gaattcattg
      361 acgaaaccat tgaatttaga accaacgctg ttgattgttg agaatgtacc taacacatgg
      421 tttacgtctt ctgtttggtc gtagtaaggt ttgtaacaag ctactacgat caattgtcca
      481 atcgctgcac caatcaattg tgcaatgata taaggaacaa cttcagccca agggaataga
      541 ccattagatg ctaaagcaat tgtaaatgct gggttgatgt ggttaccgct gattccacca
      601 aaaatcattg ctggcatcat aaccccgaat ccatacccga cagcaatcag catccagtca
      661 ctgccatatc cttttgtacc ttttaaatct acgtttgcta cagcaccgtt acctagaacg
      721 attagtaatg ctgtaccaat catttccgcc gcaagacggg tcattagtga gtaatccata
      781 aatacctcca aaagttataa aaatgcaaaa aaaaaagaaa catcaacacg aaaagcatcg
      841 gtgcagtgtt tcgtgtcgga aggatttctg cagtcttaac aaatgtgaat aaaaaaatga
      901 attccattac ttataagaaa ccagaccaac agtaaaactc caactctttt taaaagttct
      961 ccacaaatca ccaagcttaa ctataaatat accaaaaaaa aaacgttttt tttctcaaaa
     1021 attgtatctt agaaacagca tgttttgaaa ctttcagaaa aggtttgtta gtaaaatgaa
     1081 agctatacgt aaggagtgtt gtttgatgaa attttttcaa gagtttttca ttattatttt
     1141 cttttctgta ttaggagaag gcatacggat ttttgctcat ttacctattc ctggaagtat
     1201 cttaggtatt ctttttttat ttttagcatt tgaaatgcat cttgttgatc ctgaaaaaat
     1261 cggagcaact ggtgattttt tattgaataa tctagccatt ttatttgttc ctgctggtgt
     1321 aggtttattg gaatattttg atgatattgc ttcgatatgg cctgttttac tgggagcagt
     1381 cgtcgtgtgt tccatcgtca cgatggttgc agcgggaaaa acggcagaag gtgtagaagc
     1441 tttgctgggc tatgtccgta agaaaaaagc agaaagggta tctgtaaacg aaatggagga
     1501 gaatcaaatt gactgagttt tttgtgaatc cattatttgg cttaagtttg actttaggag
     1561 tgtacgtatt atctgacaaa tttttgcgga aatataaact gcctgttttg aatcctctcg
     1621 tattatcgat tgttgttatt atcttatttt tgcatttttc tgggatcagc tataaagact
     1681 ataatatcgg gggcaatttt ttgactatgc tgattactcc tgcgacagtg gcacttgcca
     1741 tccctcttta taaaaacttc cgtttactga aagagaattt ttatcctgta atggctgcga
     1801 ttttagcagg aatagtcgca aattgcttgg ttagtgtagg gttcggttac ttcttctctc
     1861 ttcataaaga gatggtgatc tcattactac ctaaatctgt aacgacggct atttctgtcg
     1921 atttatctca tacgatgggc ggggtgaatg ccgtgacact tgctattgtt gtctctacag
     1981 gtatttttgg ttcgctgatc gccactcata ttttccgcct attcaagatc gaaagtccag
     2041 ttgctcgcgg tgtggcgtta ggaagtactt ctcatgctat tggtacagca aaagcaatcg
     2101 agattggtga aatagaagga atcatttccg gacttgcgat atgcgtcaac ggaatattga
     2161 ccgttttatt gctaccgtta ttctttcagc cttttgctgg cttgttttga tgcgaaaacc
     2221 actattttat gctacaataa ccaaaacgtt cgagcataaa aaaggaggga aagacgtgta
     2281 tttgtcttcc gagtatctta aacaatttga taaagatcta tattataaga ttctcctcct
     2341 agaaagtttt gaggatcaag cttggcatac cgctgcacaa ttagcgcaag ttgttcagct
     2401 ggatgcccgc agcgtgtcga aatacctgaa cgagctgtct aaaaactatc agcagtttag
     2461 cggtaagaca caccctttgt ttacaaaaaa tcaccgttct ggttataact tttatgatac
     2521 gctcgattca attgaacatg agcgtttttt gatctatctc gtgcaaagta cgctgaaatt
     2581 ccagttgctg cacgacattt tttttgaaga attccataca atgtaccaat ttgcgcaaaa
     2641 gcattacatt agtgaatcta ctgctcatcg aaaaatcaat gaatggaaac agcaactgca
     2701 aacttacgga attcggctgc aacgaggtac atatatcgct caaggcgaag aagaaatcat
     2761 tcgactttac ttgcatatga cattctggca gttgtttcga gggaaaatct ggccatttga
     2821 aacgatttct caaatggacg taaagaatat ggcagaacat atcatggctt tttttaatgt
     2881 tcgtctgaac gagatcaaaa aaagacgatt ggaatatatg ctaggtgcct tttttttaag
     2941 aaaatcacag aagcattatg ttgtattgaa tgagaaaaaa agacggctga tttctgacaa
     3001 tctgttgttc cagcgatttt gccaggtcat ggagccggta tttcctaatt attttcaagt
     3061 agaagacgag ttaggcgcat tatttcttgt actgatgact cgtgaagaat attatagtga
     3121 tcctaagata cggaagaaaa tttttgattt tcatcaacaa gcaaaaacac cgccctttac
     3181 agccctttca gaagcaaaag ccgctctttc tctttatcag gaagagcagg ggctgccagc
     3241 agaaaatcta accttcgagg cagaaaacta tttattcagc agtcattttt tcgcctatct
     3301 ttttcctaat gcgaaagaaa cgattgatgg caatagtagt gattttatta atcatttagt
     3361 tattgaaaac aaggaattga aacaatggct cgtacatttt tttgaaagta gacacaaaca
     3421 tcccaatcat ctggcattta aaaatcatgc gtttttgatg gggcggtatc tgactgtgtt
     3481 taaaacatta ggagccttta ctccacagct tccaaagatc acgatccttt taatgacaga
     3541 tttcccatta tttgaagagc aactgttaga ggagggatta cggacatttt tccgtaatga
     3601 gtatcagctg atttttctgc caacagatta tcgggggaga gaagttgatc ttctgatttc
     3661 gacaagtaaa gtccaccgca aaccatgggc ggatcttgac tattttattg tgactgaaga
     3721 actaaaatta attgattaca tccaactatc tcaaaaattt gaaatgattc aaaaacaaaa
     3781 actattaaaa caataacaaa gaaggagaaa aaagatgaca tttgaagaaa ttttaccaga
     3841 attgaaaaaa ggtgcaaaga ttattcgtaa aggatggagt ggatttgaac tttatgttgt
     3901 tctcgtatcc gatgatgaat ttgatggctg tccggtgacg ccgtacttat tgatcaaaac
     3961 aagtgacgaa ggtttttcca gcttcgctcc tacagtttgt gatattttag cagatgattg
     4021 ggcgatcgta gaatgaaaaa ccagtatcca gatctagcta aacaggttgt atttatcaca
     4081 ggagctgctt ctggaattgg tgctgcgcaa gcccgagcgt ttcttgaaca agatgctttt
     4141 gtatttggat tagatcaaaa gttcggtaaa atggaagaaa tttctttgcg atttcctgaa
     4201 acttttgcct acgcactagg tgatgttcga caaatgaaag aactccaaca agcggtatcg
     4261 aaatgccaaa atcattttgg tgaagttacg attttactga atacagcggg gatattggat
     4321 gcctacaaac ccttgatgga aactgacgaa tcgctgtggg atctgattta tgagacgaat
     4381 gtgaaaagca tgtatcagct gacaaaaatc atccttcctg atatgatccg ccaaaaaagc
     4441 ggaacgatca tcaatatggc ttcgattgct ggcttgattg ctggtggagg tgggatcgct
     4501 tatacaagcg cgaaacatgc gattgtcgga tttaccaaac aactcgctct ggattacgca
     4561 ggacagggta tccgagtaaa aggaattgct ccaggagcca tccaaacacc aatgaatgcg
     4621 gctgattttg aagggaaagg tgagatggca gagtgggtgg caaatgaaac accagtcaag
     4681 cgatgggcac agccggaaga agtagctgag ctgacgttat ttcttgcctc tcctcaagca
     4741 agctacatac aaggaacgat catcccaatc gacggcggat ggttgttaaa ataaccttgt
     4801 gtttttttca agcttctgta tgataaaact aaagagagaa acaacggttg atgataaaaa
     4861 aagtcgatga ctgttcccga cattcgatgc cgaacagcca gttcaaaaaa ttctttttaa
     4921 taatcgttaa tattcgaaac taagcggctt ttcacgacct cttgatataa acgatattca
     4981 aaagcttgca actgcggtaa caagtccagc caaatgaaaa atataaggag ctatttttat
     5041 ttgaccattc ttattacttg ttgcagggca gctttttcac taccttctgc gacacttcag
     5101 ttggaatttt cttcccatcc tttggtcgcg gtcattacca agataaaatt atcttgcaaa
     5161 ggagaaatag aacatggaaa aaaataatac ccgttcagcc aaacgctgga caacgacaga
     5221 tgtgactcgg atggcgctag tcactggttt atatgtggca gtgacgctgg ttttgtctgt
     5281 ctttagcttt ggagtgattc agattcgtct ctcggagatg ttcaactatc tgtccttgta
     5341 taacaaaaga tacatcgtcg cggtaacagc gggagtagct ttggctaata ttgcttctcc
     5401 tcttggactg atagatgttg cagtaggaag cgtcagcacg ctgcttgtat tgcttatcaa
     5461 ctataaaatc actagtcgca tcaaaaacat gaaaatcaaa atggccgtga cagcatgcgt
     5521 atttgctttt tccatgttta cagtagctgg tcagctaacg attttatatc aactaccttt
     5581 tttcttgaat tggtgggtga ttgctttagg agaattggca tcaatgattg tcggtgggat
     5641 aattatttat tggatcggta aaaaagtgga tttgtcaaaa taaagatctg tttaatttaa
     5701 aatagggcag catggaagag actgaatgtt gagtcttctt ccatgctgct tttttgatta
     5761 atttgtatga agaaatcgat ttagccgttt tttcatcaag ataccgatat aagctgctcc
     5821 agttgccttg attgcttccg gcagtaaaaa cggcagtagt ccactggcaa atgcagttgt
     5881 aaaagtaaga tcaccactta ttttcagcca gatcgttccg cagatcaatg cagcaagaga
     5941 gcccattaga ttggcaaaga ttgcatataa gtaatgagca tccgttcttt cgatcatcca
     6001 accagttatc cacgtttgta agagaaatcc aatcaaatat ccgccagttg gcccaaataa
     6061 aacagctata cctccagtca tccctgaaaa tacaggaaga ccaatcaagc caagtaaaag
     6121 ataaactcca acagatatca atcctagttt tcttccgaga aaagttgctg ttaatccaat
     6181 agcaaatgtt tgccctgtca aaggaaccaa accaaaagga atggtcatct gagaaaggac
     6241 agaaataatc gcggcaaatt ccgcagcaag tatcaattct ttcaatgttc ggttcataac
     6301 gccctctttt cgttaactta atatttttat ttggttaacg aaattgtaaa acaaagtgat
     6361 tactttgtaa atagaaaata taaaaaaaga ccagctatcc aatagatagc ggtctttttc
     6421 aagaaagctt ttgaaattat aagctttggt tgtagtattc aacgacaaga gcttcgtcga
     6481 tttctggata tagttcgtca cgttctggta aacgagtcaa tgaaccttcc aatttttcag
     6541 cgtcaaagct tacgaatgct gggcgtccaa cagttgcttc tacagcttct tttactgtta
     6601 cgatgttttg tgatttttca cgaactgaga tcacttgacc cacttctacg tggtatgaag
     6661 ggatatcaac gcgtttgcca tcaactaaaa tgtgaccatg gttaactaat tgacgtgctt
     6721 gacgacgagt cgttgcaagt cctaaacggt aaacaacatt gtctaaacgt tgttctagta
     6781 agatcatgaa gttaacacca tgtttacctt ctttgatttt gctagctttt acgaacaagt
     6841 tacggaattg acgttcgttc attccgtaca tgtgacgaag tttttgtttt tcagttaatt
     6901 gcatgccgta ttctgattgt ttgccacggc tattaggtcc atgttgacct ggtgcgtaag
     6961 ggcgacgtgc taattctttt cctgtgcctg acaatgagat gcctaagcga cgagaaattt
     7021 tccatgatgg tcctgtataa cgagacatta aaatttcctc caatgaatat aagtttttgg
     7081 agtaaaataa tccgttgaaa aattcataat catatagttt gttcttcaat cttcaccttt
     7141 gcagccgcgg ttacacaatc gaacccgaga cggggcaaca aactagggat gagttattat
     7201 ttttctgctg cattatttta cacaaattac agtatatgat agatcatcca cgaatgtcaa
     7261 gataattagt acataaaaac gctttacaaa cctaggctgt ctttataaaa tgagagggta
     7321 tgtgcaaatg gaaaaaagcg aaggaagttt aaggagaaaa tcaatgaatc cggtatcacc
     7381 attatttgag aaaatcgatg cttcaattga aaagaaggcg aatctttttg aaaacagctt
     7441 ttcacgttac gctgttcgag cggttctcgc ctgtttgttt ttgactttag gaacggctgt
     7501 ggcatttgcg atcgcgatga agggggaaga tatcgcgcat ggtctaggaa agattttata
     7561 cgcatttatg ttcagctggg gtctggtcat gattctatac atgaacgccg aattaggaac
     7621 atcgaatatg ctttatatga ccgtgggtgt ttttcggcag agacttgctt taagtaaggc
     7681 agccaagatt ctatttgcct gtattttttt caatatgatt ggcggtatat tatgtggatt
     7741 tctaatttct atgactacgc catttcaaga tttaacgttg gacaacttta tgttagaatc
     7801 aatagcagta aaactagcaa aaccttcagc aacgattttg gtggaaggga tgtttgcgaa
     7861 tatcgttgtc aataccgctg tactgatcag catgcggatg aaagaggatg tcggaaaagt
     7921 gatcacagtc gtattcatca ttttcatttt tgctttttta ggatatgaac acgtgatagc
     7981 gaattttcct gcctttacgc ttacttactt tgcttctcac ggacagatgg atggaatgac
     8041 agtcagcaat gtgttacata atttgttttt tgctttggca ggaaattata ttggtggcgg
     8101 tttagtaatg ggactgggat atgcttggct gaatcagtca aaatcatcct atgtggacta
     8161 aaaagtcgtt cattaaaggg gaagtgccat ggaagtttta gtttttccaa aaaatgagga
     8221 aaaagcgtta caaatggaaa agtacatgaa aaatcttttt tcctttgctg gagtacctaa
     8281 gccggaacgc gctcttttac aacaaccgtt actggatgag agcaaaaatt tatctatttc
     8341 tgaagtttta gcttttgttc attattatta tgaacaaatc gaaagagagt atcagtatgt
     8401 agcgatcgat ttagtccaga aaaacatcaa acggcttaca tttgaagact tagtcgtatt
     8461 gttgccacta gttcagaaaa aagaatggtg ggacagcatc gactcttgga gaaaagtata
     8521 cagcacatgg tgtaaagcct acccagagca gcgtgaagaa gtctttcaat tgtttgaaaa
     8581 aaaggaagat ttttggctac gtcgaatagc aatcacgttg caattaggtt ataaacagca
     8641 aacagacaca ggactattga tccgagcaat agacgaagat cgtcaaacaa aggaattctt
     8701 tatccaaaaa gcaattggtt gggcattacg cgattatagt aagaccgatg ccgattgggt
     8761 aaaaagacag ctgacaacag atttgagtaa gttagctgtt cgagaggcaa gtaagtattt
     8821 ataagaaagc gagacgacaa gagatgagac gcaaattatt tgcttttgat attgatggaa
     8881 cgttgttaga ttcaaacaaa caagctttag atagcacaag agaagcattg gaaaaattac
     8941 gcaaagccgg tcatctggtc acgattgcta cagggcggag ccgatttcat gcgcaagaga
     9001 tcattcgcga tcttgatttt acgaactaca ttttatgtaa tggagcggcc ggttttttag
     9061 accatgaaca agtatataag aatttactag atcgcgacca gttggatgcg ttcgttcaag
     9121 aagcgcatca tgagcagatc gatacagctt ttgtcagctt agacaatatc aagcgttctt
     9181 cttccaatga tgtaacggtg atggaagaag cgatgcattc tttcggtgct gtcttgcctg
     9241 aattagatca gttttttgca gaggaacaag aaatatacca agcgttagca tttttcgatc
     9301 aaacatatga tgggaagttc tcttcatatg ataaaattcg atttgtccgc tggcatgaga
     9361 acagtgtaga tgtcgtacct aaaaatggtt ctaaagcagc gacaattctg cacttagcag
     9421 aacaagtagg catccctcat gaagacatca tcagctttgg cgatggacaa aacgaccgtg
     9481 aaatgttgcg catgtcagga attgggatag ctatggggaa tgctgtgcca gaagtacaag
     9541 cagaagctaa gatggtcact gatacaaacg atcaggatgg aatttggaag gcattgaaag
     9601 agttaagcgt gatttaaaag aggttgtgaa aaagctgttc tgcatcaagt aataagccca
     9661 gccaaacaaa aatagctcct cctatttttc gtttttctgg gcttattacc gcagatgcaa
     9721 gctttcgaac accgtttaag gaagaggtcg tgacagaagt ggtcagtttc aagaaataag
     9781 aagggattta cgaaaattgc ttctcaaatt tttgtaaaat tacggcttat ttctgaagaa
     9841 gtagatgaaa caacgtttat tcgggaaatg ggactgtgac aagatgtttg tcatagtccc
     9901 atttttttat tttatttttc aaaactaaga aataccagga aagagttcct tttgtttgac
     9961 cttttctttc ttattgaaaa caactataat atagagtgat gttaaaagag aagaggaatt
    10021 tagtgtgcgg gtattgttta ttggtgatgt agtaggttca atgggacgag agatgattac
    10081 tgaatatctt cctagattga agaagaagta ccgtccgcaa gtaacgattg taaatggtga
    10141 gaatgccgct tctggacgtg gaatcacaga aaaaatctat aaaaaatttt tgcaagacgg
    10201 cgtagatgtc gtgacgatgg ggaatcatac gtgggacaac cgcggaatct ttgagtttgt
    10261 aaatgaagct aaaaagatgg ttcgtccggc aaattttccg gaagggacgc ctggacaagg
    10321 gatggtcttt gtcaaagtga accaagtcga actggcagtg atcaacatgc aggctcgttc
    10381 ttttatggtg gacttggatg atccttttcg taaaatgaat gagctggtag aagaagccag
    10441 aaaacgtacg ccgatcattt ttgtagattt tcatggagaa acaacaagtg aaaaacaagc
    10501 aatgggctgg tttttagatg ggaaagtttc agcagtggtc ggtacacata cacacgttca
    10561 gacaaatgat gcgcgaattt tgccaagagg aacagcgtat ctgacagacg ttgggatgac
    10621 aggtccctat gatggtattt tgggtatgcg cagagaacct gtaatcgaaa agtttctgac
    10681 tgcattacca aaacgttttg aagttgtgga acaaggccga tcgattttaa gcggctgtat
    10741 cttggaattg gatgatacga caggtcatgc aaaagaaatc cagctgattc agatcaacga
    10801 tgatcgaccg ttcatggagt agaaagagag gcagtttttt gcagcaggag ccggaaattc
    10861 aaaaagaagt aaggaaactg acaaaacttt taagagagaa tgaaacgatc attcgctaca
    10921 aagaacttga agaaaagatc cagcaaaacc agtatttagc tgagttgaga gaaaaaatca
    10981 aacaagcgca aaaagatgct gttcattttg cccactatga caaaccagca gcagaaaaag
    11041 aagcaatcaa acaagcggat caattcatgc aagaatttga tcagcatccg cttgttgtag
    11101 cttatagaaa acagctgttg gaagcagatg atctgcttca tcatttaaca actatgatac
    11161 aagaagaaat caatggacaa atagaggagg aaaaacatgc ctcaaaaaac taaaaatact
    11221 cctatgatgg aacaatatct aagcatcaag gcccaatacc aagatgcttt tttgttctat
    11281 cgtttaggag acttttatga actattttac gaagatgcga tcaaagcgtc acagcttttg
    11341 gaattaacgt tgacgagcag aaatcgaaat gcagaagaac ctattcctat gtgcggtgta
    11401 cctcaccatg cagcacaagg atatatcgat gccttgattg aaaaaggcta taaagtagcg
    11461 atttgcgagc aggtagaaga tccaaagacg actaaaggga tggtcaagcg cgaagtgatc
    11521 cagctagtca ctcctggtac agtcatggac agcaaaggat tgtcggcaaa agacaacaat
    11581 tttttaacag ctgtagttag tcaaggaaat gaatttggct ttgcttatgc cgatttaagt
    11641 acgggagaat tgaagacggc tcggttgcat gatgaagaag ctgttttaaa tgaagcctct
    11701 gcattgcaga caaaagaact cgtattaggc agtgagatca ctgataccct tcgtgaacag
    11761 ctaagcgggc gtttagggct agtcttttct caacaaaatg agatggaaga aaacgcggaa
    11821 tttagctttt tgacaagcga actagtcgat ccgctggaaa aagaagcaac cggcaaacta
    11881 ttgacttatt tatcggtgac acaaaagcgg agtttagctc atatccaaaa agcagtagaa
    11941 taccaaccag atcatttttt gaaaatggat tattattcaa aattcaacct agaattaagc
    12001 caatctattc ggactgggaa aaagcacggc actcttctat ggttgttaga tgaaacaaaa
    12061 acagcaatgg gtggccgttt actaaaacaa tggctagacc gtccgcttat ccaggcaaaa
    12121 caaattaaag caagacaaga aatggtcgct tctttgctag acagctattt tgaacgtatc
    12181 gatttgcagt cagcattaac gaaagtctat gatctggaac gcctagcagg tcgagtagct
    12241 ttcggtaatg tcaatgggcg agacttgatc cagctgaaaa cttctttaga acaagtgcca
    12301 atgatcagag ggttgattga aggaatcgat caaggtcaat ggcaaagtct gctttcagaa
    12361 atgcagccga tggaccatct cgtccaattg atcgaccaag ctatccaaga tgatccgccg
    12421 ttacaaataa cggaaggaaa catcatcaaa gatggattca atgagcagct cgatatgtac
    12481 cgttctgcta tgagaaacgg aaagaaatgg ttggcagaac ttgaagcaaa agagcgtcaa
    12541 gaaacaggaa tcaagaactt aaaaatcgga tttaaccgcg ttttcggtta ttatatagaa
    12601 attacaaaag caaatcttgg aaatgcagaa ctggagaagt atgaacgaaa acaaacttta
    12661 gcaaatgcag agcgtttcat cacaccagaa ctaaaagaat tggagacaca aatcctcgaa
    12721 gcagaagaaa aatctgttga tttagaatat cagttgtttt tagctgtgag agaagaagtc
    12781 aaaaaggcta tccagccgct acaagtactt gcaaaagcaa tcagtgcagt agatgtgcta
    12841 caaagttttg caacgatcag cgaacgctat cagtatgttc ggccagaact tgtcagtgac
    12901 aagcatcagc ttctgatcaa agacggacga catcctgtag tagaaaaagt attaggacat
    12961 caggaatata tccctaacag cgtagaaatg gcagaagacg aaatgatctt gctgattaca
    13021 ggaccgaata tgtctggtaa aagtacgtat atgcgacagt tggcattaac tgttctgatg
    13081 gcgcaaatgg gctgtttcgt tccggcaaaa caagcagttt tacctatttt tgatcggatt
    13141 tttacccgaa ttggtgcaag tgacgactta attgctggac aaagtacttt tatggtagag
    13201 atgatggaag ccaatcaagc cctgcgttat gctacgccaa acagtttgat tttgtttgac
    13261 gaactagggc gaggaacagc aacctatgac ggaatggcgt tggcccaagc aatcatcgaa
    13321 tatatccatc gtcatgtaca agcaaaaaca ctcttttcta ctcattatca tgaactgacg
    13381 gtacttgaga aagaacttcc gcagcttaaa aatgtccatg ttggagccgt tgaaaaagac
    13441 ggagaagttg tcttcttgca taaaatgatg gatggacctg cggataaaag ctacggcata
    13501 catgtggcaa agatcgcagg attgccttcc aatctactag aacgagcagc agatatcctg
    13561 catacgctag aaaatggcga taacggacac catactgttc cagctgaagt agaagagaaa
    13621 actaaaacag ccaaacagga gcaaataaaa ccacctgcag aaaaagtaaa tcaagaccat
    13681 atacaagacc gtgtaaaaga agaaaaccaa cagctttctt tattcagtga attatccgaa
    13741 aatgaaacag aagtcattga atcactgaag caaataaatt tactagaaat gacgccaatg
    13801 gatgcactaa acacattata tgaattacaa aaacaactgt aggaagaagg cggatatcga
    13861 tggccaaaat ccaagaatta tctgaacgtt tagctaatca gatcgctgcg ggagaagtag
    13921 tggagcgacc agcttccgtt gtgaaagaat tagtggaaaa tgcaattgac gccggcagta
    13981 ctcagattga tatcttagtt gaagaagcgg gactgcggac gatccaagtg attgataacg
    14041 gagaaggcat tttggcagac gacgtagaga atgccttcaa gcggcatgcg acaagtaaga
    14101 tccataatcg cgacgatctt tttcgcatac gaacgctggg ctttcgaggg gaagctttgc
    14161 caagtattgc ctctgtttct gaaatgactc tggaaacggc gaatcaggaa gaaaaacaag
    14221 gcacctatct gtcgctgaaa ggcggagaag ttattgagca tcgaccagca ccactgcgtc
    14281 aaggaacgaa gattaccgtc agcaatctgt ttttcaatac gccagcccgc ttgaaatacg
    14341 tgaaaacact gcacacagaa ttagcgaaca tcggggacat cgtcaatcga ctggcattga
    14401 gtcatccatc gattgctttt cgtttagtac atgatggaaa caaaatgctg gcaactgctg
    14461 gaaatggcga tctgaaacaa acaattgcgg gaatctacgg attatctacc gcaaaaaaaa
    14521 tgctgaaaat cgaaggaaaa gatctagatt ttgagttatt tggctatgtt tcattgcctg
    14581 aggtgactcg tgccagtagg aattacttat cgacgatcat caatggacgt tttatcaaga
    14641 acttttcctt gaataaagca atcgttgcag gttatgggtc aaaattaatg gtcggtcgtt
    14701 tccctattgc tgtattggaa atcaaaatgg acccgctttt agtagatgta aatgttcatc
    14761 cgacgaagca ggaagtccgg ctgtcgaagg aaaaagaact aacagagcta attagtaacg
    14821 ccattcaaaa agcattgtct caagaaaatc tgattccaag tgcagcggat aatctacggt
    14881 ttaagaaaaa agtacctgat cagcctaaaa cagaacaaat cgaaatcgat ttgtcctacg
    14941 cttttgaaga agaaaaacct aaaaagccaa gtagtttgaa ttttgatcga gagacaggta
    15001 cctttttcgt agaagaacta aagaacacat ttgttgacag aattgttgat aagtctgtgg
    15061 aaaatgttga aaactattct ggtttttctg aagaaaacac cacttatcca gaaaaaacag
    15121 cgaaaacggt ggataagttt ggtgaaaatg ttgataactt tgtagaaaaa acagtggaaa
    15181 aatctgaaaa gaaagaattt cccattgtgg ataacatgga gaaaacaaat gaagaacaag
    15241 cagataaatc cgtagaagag gatgaaaaga tttacgagga agaattgaca ctccatcctg
    15301 aatttgattt cactcaagga aacgacaaaa cattagaaca agccatcaag aaattagaaa
    15361 cggaaaaacc agtacaacgt tttcctcagt tggaatattt tggacagatg cacggaacgt
    15421 atctttttgc ccaaagtagc gatgggttgt acatcattga tcagcatgct gcccaagagc
    15481 gcattaagta tgaatatttc cgggaaaaaa ttggggaagt atctgatgat ctgcaagaat
    15541 tgcttgttcc atttgtgtta gactatccaa acagtgatgc tttgaaatta aaagagcaaa
    15601 aacacttgct agaagatgca gggatttatt tagaagaatt tggtcaaaac agctttattg
    15661 tacgggccca tcctacttgg tatcccaatg gagaagaaga atcgattatt cgggagatga
    15721 tcgatatgct gctgacaact ggaagtgtga gtgtaaaaaa attccgtgaa gcaacagcaa
    15781 tcatgatgag ttgcaaacga tcgattaaag ccaaccatta tttgaatgaa gcacaagcac
    15841 gtgtgctgct gaaggatctg gcacgatgcg aaaatccttt caattgtccc catggccgtc
    15901 cagtattgat tcactttacc aattcggata tggaaaggat gttcaaacga atccaagacc
    15961 cgcattaagt caaagagaag agggaaaaca tgaagattgt attagcatcc caatcaccaa
    16021 gaagaaaaga gttattggct catatcgttt cagaattcga gattgaacct gctgatatcg
    16081 atgaaacgcc atttccagac gaacagcccg tcgattatgt tcgtagaatg gctgaagaaa
    16141 aagcacgaac tgtctgggaa caagatgaaa aagaagacca tttagtgatt gccagtgaca
    16201 cgactgttgt tctcaatcaa gagatcatgg gtaaaccaga agatctggct gaggctgaat
    16261 tcatgctgaa aaaactaagc ggggaaacac atactgtata tacagctgtt gttttaaaaa
    16321 caaaggaacg agaagaacgg atactagcag aagcacatgt cactttttat cctttgacag
    16381 acgaagagat caaacgctac ttggagacgg gggattatgc ggataaggca ggggcatacg
    16441 gcatccaaaa tgctgcgagt gtattcgtca aagaaatttc tggagattat tacagtatcg
    16501 taggatttcc gattggtgct gtcaatcagg cactgaaaac attcatttaa acaaaaaagc
    16561 ggactatctg attttcgatt gaaaatccat gatagcccgt tttttttatt gaaaagatta
    16621 cttatctact ctgactaaga ttttacttca gctttaccga ctgcttcgcc cgggcgaaca
    16681 agtcctgatt ggtcaagaga aagtcctgca actttttcat tattggtcaa agcaacaata
    16741 atgtcagttt tcttgccagc ttgttctatt tctggcaaat ccatttcagc aatcagggtc
    16801 tctggtgtga caaggtatcc ttctttcacg aatacattga aaggaacacc ctttagttca
    16861 acagtatcta atcccatgtg aacaagtact tccagcccct cattagaaag aataccaatg
    16921 gcatgttttg tttcaaagac actcgtcact ttaccgttta ctggtgcata gactttgccg
    16981 tttgacggtt cgacagcata accgtcaccc atcatttttt gtgagaaaac tgggtcattt
    17041 acttcagtta tttccttgat ggtccctgca gcgactgcga ataatgtttc ttttgttgca
    17101 actgccgtac cagttgctga aacaggttcg aaagactgtg gcgttgctgt tgcgccattt
    17161 gctgtttgaa gttgtacatc agcagcattt tcaggaacag caggatcaat cttattcaaa
    17221 attccctgac gtctaaagat gatcgtcaag ccaaatggaa tgatgacagc aatgatcatt
    17281 gcgatgatga aaggtaccca tgtttctgct tggatagcta gtattcctgg caaaccgcct
    17341 actccgatcg cgttagctcg aacacccatc aagttagcaa acatgccagc taatccagag
    17401 ccgaccattg cagcgacgaa aggatagacg tatttcaaat tgattccgaa catagcaggt
    17461 tcagttacgc ctaagtaaca agaaatcatt gctggaatcg agatttgttc ttctttttta
    17521 ttcccacgat gtaagaagat gatggctaag actgcagagc cttgggcgat atttgataaa
    17581 gcaatcatcg gccataaatt cgttgatccg aaatctgcaa tcagctgcat atcgatggca
    17641 ttggtcatat ggtggagacc agtaatcact aaaggagcat acaggaatcc gaatacggca
    17701 ctaaacaacc agctgataga agacgtcaat ccagtattta cgatatttga gatccagctt
    17761 ccgactgtcc agccgatagg acctaaaata acgtgtgcag ctaaaacagt tggtaacaat
    17821 gaaaacaatg gaacaaaaat catcgagatc gactgaggga tatatttgcg gaagaagatt
    17881 tctagatacg ctaacataaa ccctgccagc atggctggaa taacttgcgc ttgataacca
    17941 atcatctgga cttgagcaaa accaaaatcc caaaatggaa tatctgctgc ggctgtggaa
    18001 gctacactat aagcatttaa taattgcgga gaaactaacg taattcctaa aacgattcct
    18061 aatatttgtg tagtacccat cttttttgca atactccaag tgatacctac tggaagaaaa
    18121 tggaaaattg cttcacccgg taaccacaaa aaggcattga caccattcca aaacttcgag
    18181 tgttcaacga ttgttccacc aagactttca aactggatac cttcaagtac atttctgaat
    18241 ccaaggatca atccaccgac aatgattgca ggaatcagtg gtgtaaagat ttctgctaaa
    18301 acggcaatag cacgttgaac gggatgaagg ttttgttttg cagctgcttt tccttgttct
    18361 ttggaaaccc cttcaactcc agatactgca acgaagtcgt tataaaaagt agaaacatcg
    18421 tttcctatga tgacttggaa ctgtcctgca ttcgtgaaca tcccttttac gctaggtata
    18481 tcttcgatcg ctttttcgtc cgcttttcct ggatcattca ggacaaaacg catacgagtc
    18541 gcacaatgac taactgcagc aatattttct tttccgccga tatcatgtaa cagcttctcg
    18601 gcatctgctt gatattttgc catatcaata aacccctttc tcttaacttg tctatgcaag
    18661 ttgtttcttc atttactata ctttttttcg gagagaattg caagcgtttt attaaaaagt
    18721 acgagagaaa atgatatcgt tttaaaaagc ttaaaataag cttttcttaa aaataggaac
    18781 attgaaatac aaaaagagct gtagtatagt gaagaaatga tggaagaacg agtgagggaa
    18841 aaaacatgaa taagttcaat gaaatttttt tagatttgga acagaaaatt ttagcgaaag
    18901 aatatcctcc gcattcgctt ttacccagtg agaaccaatt gatcaaaatt tatggtgttt
    18961 cacgagaaac aattagaaaa gcgctgaatc ttttgactac ggaaggttat attcaaaaaa
    19021 aacaaggaaa aggttcgatc gtactggatc ggaatcgctt cgactttcct atttctggat
    19081 tgactagcta taaagagcta caggagaccc aacgtattcc aagtgaaacg atcatccata
    19141 cgttagaaga aacagaagtg acaaaagcat tgaacgagat cactggctgg gagatcggtg
    19201 cgcctgtttg gcatttgata cgcgaaagaa aaatcaatgg cgaagtagtt atattagaca
    19261 ccgattatct attaaaggaa atcgttccta ttttaactcc agcacaagca caaggatcga
    19321 tctatgaata ttttgaaaat gagctttctt tgacgattgc ttacgcgcaa aaggagatca
    19381 cagtagaaga agtaacggaa atcatgaaaa cagcgatgga tcttcacgat gacacttatg
    19441 cagtagtagt cagaagcctc gttcatctgg aagatacccg ctgtttcgag tattctgagt
    19501 cggttcaccg attagataaa ttccgtttcg ttgagtttgc ccgacgccga aaagtgtaaa
    19561 tagttcaaaa gaaagcaaat tgttggcatc tgtccacttt ggcgctatga taggatcaca
    19621 aagggggcat ttttaatgga taaaccaata agaccagaaa aagaagaact gaaagaaaag
    19681 ttatcaccca tggcttatgc agtcacacaa gaaaatgcaa cagaacgacc atttagcggg
    19741 aaatatgatg atttttacga aaaggggatc tatgtagata tcgtcagcgg tgaaccgtta
    19801 ttcagctctg cagaaaaata tgatgcaggt tgtggctggc catcattcag caaaccaata
    19861 acgaaaagac aagtgcgcga aaaagccgat ttttctcatg gcatgcatcg aatagaagtt
    19921 cgaagcaaag aagcagattc tcatctcgga catgtgttta ccgatggacc agtagatcaa
    19981 ggtggtctac gttactgcat caattctgcc tcactgaaat tcattccata tgaaaagatg
    20041 gatgaattag gttatgggga attcaaatca cttgtagaat aatggaaata cacaaagagc
    20101 ggtacaatac ggggatttac tcgatcgtcc gctctttttt tattcaagcg attgctattt
    20161 gaaagaaacg ctccctagac tccttttttc acaaggtgaa atgtgctaca ataaagggaa
    20221 cgtatgtgtg caaaagaaag aggactagaa tatgtatgaa tatctgacag gtgtggttac
    20281 ctttatcaac ccctattaca tagtagtaga aaccaatggt atcggctacc agatcgcact
    20341 aggaaatcct taccgctaca gtagcaaact aaatcaaaaa ataaaaattt atgtccatca
    20401 ggtaatacgt gaagatgcgc atcttctgta tggatttgat tcgctagaag aaaagcaact
    20461 gtttttgcga ttagtaagtg tttcaggaat cggtccgaaa agtgcccttg caatcatggc
    20521 aagcgaagac cactccggtt tgattcaagc agtagaatcc agtgatgtca cttatttgac
    20581 gaaatttcca ggagtaggga aaaagacagc acaacaaatg atcttggatc taaaaggaaa
    20641 attcggtgag ctgagtatcg atacaccttt tagtctattt gatgaagcaa acacaaaaga
    20701 cgctacagct ctatctgaag caatggaagc tctctcggct cttggttaca gtgatcgaga
    20761 aatcaaacgt gtagaaaaac aattaaaaga agtagataat cagacaacgg atgagtatct
    20821 acgccaagca ctcaagctaa tgatgaaaaa ataaggagga gaccaaatga cagatgaata
    20881 cttgttatca ccagaatctg gcgaaaatga actgagtttg gaaaaatctc ttcgaccaca
    20941 gctgctttct caatatatcg gacagagaaa agtcaaacaa gaacttcaga tttacatcga
    21001 agctgccaga aatcgggaag aacctttaga tcatgttctg ttgtacgggc ctcctggatt
    21061 aggaaaaacg acgatggcca tggtcattgc taatgagatg accgtaaata ttcgtacgac
    21121 gagtggccct gctatcgaac gtccgggtga cttagtagca atcttgaatg aactggaagc
    21181 aggggatgtc ctgtttatcg atgagatcca tcgattacct agagtggtag aagagatgct
    21241 ttattcagct atggaagatt tctatgtaga tatcatggta ggacaagggc caaccgcaca
    21301 tccggttcat ttccctcttc ctccctttac tttgattggc gcgacgacac gggcaggtat
    21361 gctttctgca cctttacgag atcgatttgg catcatttct catatggaat attatgacga
    21421 acaggatctg caggagatcg ttttacgttc ttcggatatt tttcaaacag agatcattga
    21481 agaaggggca ttggaaattg ctcgccgatc acgaggaacg cctagaatcg ctaatcgctt
    21541 gctcaaacgg gttcgtgatt ttgcgcaagt ccaaggagac gggaaaatcg atcgtcctat
    21601 agcggatcag gcacttactt tgctacaggt cgatcaggct ggattggatt atgttgacca
    21661 gaaattgttg cgaacaatga tcgagttata tggcggcgga ccagtagggt taagtacgct
    21721 ttcagtaaac ataggagaag agcgtgagac ggtagaagat atgtatgaac cgtatctgat
    21781 ccaaaaagga tttttaaagc gtacacctag agggcgaatt gctactgctt atgcctatga
    21841 acattttggt tacgactatc atatatgatt tttgctttta gattggagga aaatgaatga
    21901 gtgatacaac acgtacgaaa caattgatca aaaacgtatt gattgatttg tgccaaacgc
    21961 aatcttttcg aaaaatcagc gtccaaaaaa tcgcaaacga agcaaaaatc aatcgacaaa
    22021 cattttatta tcattttaca gataaatacg atttgcttcg ttgggtctat tgtgaggatg
    22081 cattgcatta tttagatcca caatgtcttt cacttgataa ttgggaagag caagcattga
    22141 aaatgctgaa agcaattgct gagaagaaag aattttatgc aaatactgtg ctttctgacc
    22201 cagaaatttt acaaaaagag ttttctcaac tgatccaaaa atcatttatc aagatttttg
    22261 aacaaatgga tgaagaaaga caactttctg caagagacaa actattttat gctcgttttt
    22321 tttcttacgg ttgcagtggt gtattagtca attggatcac gaatgaatat gaagaaacac
    22381 cgatggaaat cgctatgcag cttttccgtt tagccaagga tacggaatta tattcttatc
    22441 gtctttatgc aaaagaagag ttggaagaac agtaatagaa aaattttttg ttggaaaagc
    22501 aataatcgct aaaaggagat ggggaaatga caaaaatttt atttgtttgt ttgggaaata
    22561 tttgccgttc accgatggca gaaggcttgc tgagaaaacg aatagcatta gaaggaaggg
    22621 aagcagaatt ttttgtggat tctgctgcta caagcacgta tgaagttgga aagacaccgc
    22681 accctggaac gaaaaaaata ttaaaccaag aaaaagtaga tatgacgaat atggttgctc
    22741 ggcaaatcac accccacgat tttgaaactt ttgattggat cattggcatg gatcaagaaa
    22801 atgtagaaga actgaaacga agagcaccac gctcagcgca ggggaaaatc catttgtttt
    22861 taagtagcat tcctggaaaa gaaaaagaaa atgttcccga cccatactat accaataact
    22921 ttgatgagac atatcacttg atcacagaag gcctgaatca ttggtggaat atttggattg
    22981 atgaaaataa aataacaaac aatttgtaaa gttaacgctt tctttttaag gcgatgttag
    23041 agcatttcct tgtttttttg taaaatgtta ggtaaaataa aattaattaa gtaacacttt
    23101 cttagctaaa ggaggagtgc attcgatgaa cgaagagaca gtatcgccaa tgaagaagct
    23161 tacgaagtta gttactcata cttcgtatca actttttgat tcttttgtaa atgacactga
    23221 agaacatgct aagaatgtac gattgcaagg aaagtttatt cttgagctgc aaaaagctgc
    23281 tactgaacat agtctagtta tcttacaagt aagagcaaat cgtttgagta gcaagtatga
    23341 aacgatctca ggctgggtgg cgacaaaaac ggtcgaaaaa gaccgagtga tgatccgcct
    23401 acaaaacgaa gagcagcaga tccggatggt tcctgtagaa caaattgaaa aaataacaat
    23461 cctttcacca gcaggggaac aggaacggtt atcaaaataa tttataccag atagaaaagc
    23521 acgtatgagc ttgtaccatc aatcattact aatcaaaaat aaccgaatgc tttaagctga
    23581 tatcagtaaa acggaacgtt ttaggatgag tatcatagca tgacagcatt cggttgatta
    23641 gttgaatcga ttggatggta caagtttttt tgataaaaaa aggtcctgct agccggggag
    23701 ctagcaggat aaggagttaa aaatgaaaaa gtgttgttag ggttgtttgt tggtatgctt
    23761 atataatagt cattagttgt gaatattttg tgacgaaagt tttcgaaagt tgttaagtt
//
LOCUS       DAFBSV010000040        23655 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.041, whole genome shotgun sequence.
ACCESSION   DAFBSV010000040 DAFBSV010000000
VERSION     DAFBSV010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23655
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.041"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            257..532
                     /locus_tag="LLB18_001478"
     CDS             257..532
                     /locus_tag="LLB18_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244485.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            545..2623
                     /locus_tag="LLB18_001479"
     CDS             545..2623
                     /locus_tag="LLB18_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBK5244486.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            2783..4669
                     /locus_tag="LLB18_001480"
     CDS             2783..4669
                     /locus_tag="LLB18_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBK5244487.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            4681..5628
                     /locus_tag="LLB18_001481"
     CDS             4681..5628
                     /locus_tag="LLB18_001481"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBK5244488.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            5648..6175
                     /locus_tag="LLB18_001482"
     CDS             5648..6175
                     /locus_tag="LLB18_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBK5244489.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(6238..6891)
                     /locus_tag="LLB18_001483"
     CDS             complement(6238..6891)
                     /locus_tag="LLB18_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBK5244490.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            7023..7865
                     /locus_tag="LLB18_001484"
     CDS             7023..7865
                     /locus_tag="LLB18_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBK5244491.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            8023..8919
                     /locus_tag="LLB18_001485"
     CDS             8023..8919
                     /locus_tag="LLB18_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBK5244492.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            8922..9635
                     /locus_tag="LLB18_001486"
     CDS             8922..9635
                     /locus_tag="LLB18_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HBK5244493.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            9655..10173
                     /gene="msrA"
                     /locus_tag="LLB18_001487"
     CDS             9655..10173
                     /gene="msrA"
                     /locus_tag="LLB18_001487"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBK5244494.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            10170..10397
                     /locus_tag="LLB18_001488"
     CDS             10170..10397
                     /locus_tag="LLB18_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HBK5244495.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            10549..11100
                     /gene="lepB"
                     /locus_tag="LLB18_001489"
     CDS             10549..11100
                     /gene="lepB"
                     /locus_tag="LLB18_001489"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBK5244496.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(11183..11683)
                     /locus_tag="LLB18_001490"
     CDS             complement(11183..11683)
                     /locus_tag="LLB18_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBK5244497.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(11962..12360)
                     /locus_tag="LLB18_001491"
     CDS             complement(11962..12360)
                     /locus_tag="LLB18_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBK5244498.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            12620..13480
                     /gene="ylqF"
                     /locus_tag="LLB18_001492"
     CDS             12620..13480
                     /gene="ylqF"
                     /locus_tag="LLB18_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBK5244499.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            13473..14240
                     /locus_tag="LLB18_001493"
     CDS             13473..14240
                     /locus_tag="LLB18_001493"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBK5244500.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            14296..15153
                     /gene="dprA"
                     /locus_tag="LLB18_001494"
     CDS             14296..15153
                     /gene="dprA"
                     /locus_tag="LLB18_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBK5244501.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            15275..17353
                     /gene="topA"
                     /locus_tag="LLB18_001495"
     CDS             15275..17353
                     /gene="topA"
                     /locus_tag="LLB18_001495"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBK5244502.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            17322..18698
                     /gene="trmFO"
                     /locus_tag="LLB18_001496"
     CDS             17322..18698
                     /gene="trmFO"
                     /locus_tag="LLB18_001496"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HBK5244503.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            18896..19801
                     /gene="xerC"
                     /locus_tag="LLB18_001497"
     CDS             18896..19801
                     /gene="xerC"
                     /locus_tag="LLB18_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HBK5244504.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            19838..20386
                     /gene="hslV"
                     /locus_tag="LLB18_001498"
     CDS             19838..20386
                     /gene="hslV"
                     /locus_tag="LLB18_001498"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HBK5244505.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            20400..21800
                     /gene="hslU"
                     /locus_tag="LLB18_001499"
     CDS             20400..21800
                     /gene="hslU"
                     /locus_tag="LLB18_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HBK5244506.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            21818..22609
                     /gene="codY"
                     /locus_tag="LLB18_001500"
     CDS             21818..22609
                     /gene="codY"
                     /locus_tag="LLB18_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBK5244507.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            22691..23566
                     /locus_tag="LLB18_001501"
     CDS             22691..23566
                     /locus_tag="LLB18_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBK5244508.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
BASE COUNT         8191 a         4080 c         4983 g         6401 t
ORIGIN      
        1 tttttgtcgc agccccattt ttttgttgtg ataaaagaac aagaaaggca ggaatgggaa
       61 agtaaacatc cttttgtcag aaacttttat ctttcttaag ttttacttga tatctgatac
      121 tatttggaat agaatgaggc gttgaaaaat ttatggaaat ttctaactag caataaacga
      181 tgaaacaatg aaatattttt catccaaaaa gaactttgct ataatgatgg aagtttgtgt
      241 ataggagatc tggaaaatga gagagagttt tgaacaacaa aaaaaactgt tgcatgatcg
      301 ctatggcgcc ctttcgatgg atgaccgccg tcaaatactt tgtaagttgc gtaaaagaaa
      361 tatattgatg tatcgtcagt tggaacgtct gaaacatgat ctgcttcgtt tggagtcaaa
      421 acgtgtacag tgtgaattag aggggaacca aacacaggtt gaagtagtcg aaaccaaaat
      481 tttaaagaaa aaagaacaat ttttaaaaat gcttacacaa aataaaaaat aaaggggatg
      541 gacgatggaa tttgctgagt tagttattgt atttgcagta acgatcacct tatcgaacat
      601 agctagccgc attttgccaa tgattccagc tccactgatc caaattttcc ttggagtggt
      661 attaggtctg acagagtggg gacaatcaat cgattttgaa cctgaattgt tcttagttat
      721 gattattgca ccattgttat ttagagaagg agaaaaagca gatatttctt cgattctcaa
      781 aaatttcggg acaattttgt tcttggcatt tggaggagtc attttgaccc ttgtcggggt
      841 aggtgcgacg ttatcattcc tgttgccaag tgtcccactt gctgcctgct ttgcttttgg
      901 agcagcgtta ggtccgacag atgcggtagc agtcagttct ctttctggac gagtgaatat
      961 ccctaaaaag gcgatgcata ttttggaagg agaaggtctt ttgaatgatg catctggtgt
     1021 tactgccttc cagtttgctc ttggtgcgct gatcaccgga tctttttcag cagtaaacgc
     1081 ggggatgagt ctagtagttt ctagtattgg gggagctttg atcggctttt tgcttgtctg
     1141 gttcaaacaa aaaataattc atttgatcga aaaagcatca gcacaagatg tcacagggta
     1201 tctgctgatc gaacttttgc ttccttttct agcctatgta ttggcagagg catttgatgt
     1261 atctggaatc attgctgcag tggcagcagg tattctccaa gcttctggtt ttaggaaaat
     1321 ctctgtgttt gatgcagaat tgtcgagctt gtcccacagt acatggacaa ctattgcttt
     1381 tacactgaat gcattagtat ttatattttt aggaatcgaa ttgacgcaag tgttctcgcc
     1441 agtatgggga gacggtttat atccaaacgg tcttttatta gcgattatcg tattaatctc
     1501 tgtcatgctt tttgtgatca gattcatttc tatcagtctt ttttatgtat tcaaagatgg
     1561 cagtaaaaag ttcaaaaaac agttgaacga gatcttgatc ttaacatttg gcggtgtaaa
     1621 gggaacagtc agtttggcta cgatttttat tttgccattt tcaatcaata atatgatgtt
     1681 ttaccagcgg tctttgcttt tgtttctgac ggcgggtgtc atcttagtga ctttggtcat
     1741 agggatcatt gtcttgccta tgctgacgga aacagaggaa gcgaaaagca cggatttgaa
     1801 tgctttgatg attttagaag aggtcgttga agttttgcga aaagaaataa aggaaattga
     1861 tcgtaataca aaagaatttt tagccactga agcagtgata gaaaattatc aagaacggat
     1921 acgtgatctg tacttggaag atttaaccga tgatgaaaag caagaagtac aagaaataca
     1981 agcactgatt ttgtcgatcg aacgggatgg attggatgaa agttatcgtt cgggcaagct
     2041 ttcttctaat ggttatcgtt tttactcccg ttttctttct cgattcgaac attctatcac
     2101 aagccagatt ttgtctttta tcggcttttg gttcattgtt gtccgtaggt taatgcgaat
     2161 cgttctccat ccgaaaatgt tttggcaaag aagatatgct gatcgtcaga catttattag
     2221 tgatgaagat atccaagaaa tcagagagac atatcaaaaa aatactcagt tgattattga
     2281 aagtttagat aacttgactg atatttatga tgaaacgatg gttcaatttt ttatccagca
     2341 acgcaaactt gaaggaataa aaatgaactc ggggaatttg atttcttcgt ggatgatcca
     2401 gcaagatagt ctgtttacga aaaaaatgct aagaggttat tatcttgaaa gaaaaatcat
     2461 tgatgaatac gaagttgctg aaaaaatcac gacgttttct gcgaacagct atcgcaggaa
     2521 tatcaatttg ttagaatctt atacgatgaa caaaccatct gataactttt ctttccgatt
     2581 tgcgtttcga gcaaagtcaa aaaaaacgag tccaataaaa taaaaaggta aaaattttca
     2641 agttttataa aaaacaaaac atatcagaac aggatcgaat cggtcctgtt ctttttttga
     2701 gaacacaaaa agaacaaata ccaaaaaaat tttcctgaag ttcactattt ttatgataca
     2761 atatccaaga taaggaggga acatgttgaa agaattaaaa gtaactgacc tcaaaaaaac
     2821 ttatggtgaa aaagatttgt ttgaccagat ttcttttttg gtccacgaaa aagaccgtat
     2881 cgggttgatt gggacgaacg ggacgggtaa aacaagtctc ttaaatatta ttgccggtat
     2941 cgatagcagc gacggtgatc ggcaaacagt gttttatcca actgattacc gtattggtta
     3001 tctttctcaa gcagctgaat tttccgatga attaactgtt ctccaagcag tctttcaagg
     3061 aaacagcccc ttgatccaaa ctgttcgagc atatgaggaa gcattgatcg aactagggga
     3121 aaacggagaa gaccctgatg tgcaaaaacg ttatgctaaa gcagaagaac aaatgaataa
     3181 agaagatgct tggactacag ataccaacgc aaagattatt ttgcaaaaat taggaatcag
     3241 tgaattagat aaaaaaatca gtactttatc aggtggtcag aaaaaacgag ttagtctggc
     3301 gcaagtgttg attgatgaac ccgatttact attactagac gaaccaacaa accatttaga
     3361 ttatgaagcg atcgagtggt tggaaaacta tttgaaacaa taccgtggcg cactattgat
     3421 ggttacccac gatcgttatt ttctagatag agtagcaaac cgaatcttcg aactttcatt
     3481 tggaaaatta tacgagtata aaggaaatta tgaagcttac gtcttagaaa aagcagaacg
     3541 tgatcgtgta gaagtagaac aagaagaaaa gcgcaagcgg ctttataaac aggaattagc
     3601 ttggatgagg gctggcgtac aggcacgtgg caccaagcag caagcacgga tcaaccgttt
     3661 cgaagatcta aaggagaact tgtaccaagt aaaccaagaa gatgatttag agctgaacct
     3721 agcgacacaa cgtttaggga aaaaagtact ggaaatcaaa gatggcagtt accgtataaa
     3781 tgaccaaaca ctgctagaac atttagattt attgattcaa tctcgggaaa gactaggtat
     3841 tactggtaaa aatggtgcgg gaaaatcgac attgcttaat attctagctg gcagaattcc
     3901 cctggatagc ggtacaatgt ctatcggtga aacggttcat cttgcgtatt atacacaaga
     3961 aaatgaagaa atggcaccag ataaacggat gattgcttac ttacaagaag ctgctgaaga
     4021 agcaaaaaca gcagatggca gtcaaatcgg agtagcagaa ttacttgaac gatttttatt
     4081 tccaagattt atgcatggga cactgatagg caaactttca ggcggagaaa aacgccggtt
     4141 atttttgttg aaactgctga ttcagcaacc taatgtttta ttattggatg aaccgaccaa
     4201 tgatttggac atagcaacat tgacgatttt ggaagattat tttagaagtt ttccaggtgc
     4261 tgtgatcact gtttcccatg accgttattt cttggacaag gtagcagata agttattagt
     4321 attccaagga aacggaaaac aagaacttta ttacggaaac atgtccagtt atttactgaa
     4381 gcaaaaagag acccagcagc ctgctgaaaa agcgaaacca aaaatacaga gcaaggaacc
     4441 tgctgaaaag aagaaattat cttacatgga acaaaaagaa tgggaaacga ttgaagatga
     4501 gattgcagaa cttgaagaaa aaatctcatt gctccaagaa gagatgaatc atcaaggaga
     4561 taatttcact cgattacaag aattgcaaaa cgacgtatct gaaacagaag cacaacttga
     4621 agaaaaaatg gcacggtggg aatacttgag tgaatgggta gaagattagg aggaaaaagg
     4681 atggaacaag cgtatcttga cttaggaaga aaattgttgg aagaagggca tcgtaaagaa
     4741 gacagaacag gcacaggcac attaagctta ttcggatacc aaatgcggtt tgatctgcaa
     4801 aaagggtttc ctttgttaac aacgaaacga gtaccttttg gattgatcaa aagcgaattg
     4861 ctttggtttt taaaaggaga tacgaatatc cgctatctat tacaaaataa aaaccatatt
     4921 tgggatgaat gggcatttga acgctacatc aaaagtccag actataatgg accagatatg
     4981 actgattttg gccatagatg tttgacagat cctgaattca atgaagaata taaaaagcag
     5041 agcaagcttt tttgcgagaa gatcctaacc gatgattcct ttgctgaaac atacggcgat
     5101 cttggacaca tctacggcta tcaatggcgt cactgggaaa caaaagacgg tggctttatc
     5161 gatcaaatca aacaagtgat cgaagcaatc aaaaagactc ctgattctag aagattgatc
     5221 gtttctgcat ggaatccgga agatgttcct agcatggctt tgcctccttg tcatacgatg
     5281 tttcaatttt atgttcaaga gggacggcta agctgccaat tgtatcaacg cagtggggat
     5341 gtgtttctag gcgttccgtt caacattgca agttatgcgt tgctgactca cctaattgca
     5401 catgaaacag gtttagcggt tggcgaattt gttcacacat taggagatgc ccatctttat
     5461 atcaatcata tcgaacaaat gaaagaacaa ttgagccgag aaatacgcgc atttccgact
     5521 ttagttttga atcaggaaaa gcagtcagta tttgattttg agatggaaga tatccaatta
     5581 gaaggatatg acccacatcc ggcgatcaaa gctcctatcg ctgtttagaa tcagaaagga
     5641 tgagaaaatg ttagctgcaa tttgggcaca ggatgaaaac ggattgattg gaaaagaaga
     5701 ccgtcttcct tggcgtttgc caaatgatct gaaattcttc aaacaaatga cagaagcaaa
     5761 tacactagtg atgggacgaa aaacattcga agggatgggt agccgtccgt tgccgaatcg
     5821 tcagacgatt gttttgacga gagattcttc ctataaagca gaaggcgtgc atgtcatgca
     5881 tagtgtggaa gacgtgcttg ctctggaaaa agaaacagac ggtatctttt tcatcgctgg
     5941 agggtcagct gtttatcaag aatttctgcc attttgtacg atattatacc gtacagtcat
     6001 ccatcatgta ttcgatggag atgcttattt tccacctgtt gactggtctg attggtcact
     6061 gatcaatact agtcaaggag aaatggatga aaaaaatcgt tatccgcatc aatttgaaac
     6121 gtatcagcgt aatgagaatc ctgtaaaaag cgggacaggc gaattgacga tataaaaaag
     6181 ctatggatag actagctgtt atttagagct gtcccatcca tagctttatt ttttttatta
     6241 agtaaagaat aaaacagaga agtacataaa acctgcacct aacataacaa acaaatgcca
     6301 aacaacatgc atatagcgga tagaattcaa gctataaaag aatgcgccta tcgtgtaaga
     6361 aagcccgcct gctaccatca aaataacacc agtcattcca agagagtgat aaagaggaac
     6421 agcagccacg acacagagcc accccataaa aatatagatg atcgtagata cttttgatac
     6481 tctctcccgt ttatgcaacg tcaacgcttt atatataatg ccaagaatcg caaacaacca
     6541 gattaataca aataaagtcc aacctagcca tcctcggata ctcagcaaac aaaaaggagt
     6601 ataacttcct gcaatcaaaa gaaaaatcga actatgatcg aatacttgga acaccttttt
     6661 tgcttttgta aaaatcaatg aatgaaacaa agtagacgtt aaaaataaaa gaatcatcat
     6721 cgatccatag atagcataag agacaatatg gagggaggaa tgcaagtggg caccttttac
     6781 taaaagaacc actagtcccg cgatactcaa tccagtccca attccatggg tgactgcatt
     6841 aaacacttca tttaatattt catacgttcg attaaatttc gttttttcca tgaaaacggc
     6901 tcctttacta ggtgtaatta atgaaaaatc attatttgtc tgttatacta aaaatagaaa
     6961 ttgtcttaca tgtagtttaa catgaataag gcatcttgtt aaagaaagag agagagaaaa
     7021 taatgacaaa tgtaaaaatc gtaacagatt cttcatgtac gatggaaaaa aatgtacgcg
     7081 atgctttagg cattcgtgtc atgccgctat ccatcatgat cgacggaaca gtatatcccg
     7141 atgatgacca actagacggc gaaagattta tggaaatgat ggcgaaagca aaaaatctgc
     7201 ccaaaacaag ccaaccacca attggagaat tcatctcgat gtatgatgag ctaggagaag
     7261 acggcagtga agtgatttcg atccatatga caaaaggctt gagtggaaca gtagaagcag
     7321 caagacaagc cagtaatcta acaaaaacga aagtaacggt tatcgacagt gataccactg
     7381 accaaggatt atcttttcag gtaattcgag cagctgaatt agcaaaagaa ggtaaaacag
     7441 tagagaaaat ccttgaagaa gtcaaaaaag tacaagacaa tacaaaatta tacatcggaa
     7501 tatccacact agataacttg gtaaaaggtg gaagaatcag ccgaacaact ggtttgctgt
     7561 ctagtgtttt gaacatacgc gtggtgatga atttcgccca ttctgaatta atccctgtaa
     7621 ctaaggggcg aggaaagaaa acgttcgata aatggtttaa taatttgaaa aatgaactga
     7681 aagaattgcc aaatgtgcga caaatcggta tttcacatgc ggatgcaaaa gaattggcgc
     7741 aagaattcaa agagggtttg caagaattat tcccggacat gcatatccct gtactgcata
     7801 cgaatccggt tatcgctacg catactggta aagacgcgtt tgcaatcatg tattatgtag
     7861 attagtcgaa aagaggataa gccctcagcc tgaaaggctt gcagcttatt ctctttttct
     7921 ttataaaatt aggaaaataa ttgttttctt ttttcataaa gactaccttt ttgataaaat
     7981 ttttgataac attagaacca atcgaataca agaggtgaaa aaatgaaatt aacgaaacga
     8041 catttgatcc tcgttttgtt cccattatta attgcgatca tcatctatgc aggtttagct
     8101 gcttctatac cgaaagctgg cccactaatg aaaccagtaa ctactgtgag agaagatcca
     8161 aataaaaaag aaaaacttca ctacatagct atcggagatt cgctgactga aggagtagga
     8221 gatcaaacca agcaaggagg attcgttccc cttgtcgcaa atgatctaaa agaccgttat
     8281 aatttgaccg cggttgaaac agaaaactat ggtgtaaatg gtgaacgaag tgaccagatc
     8341 ttaaagcgag taaaaacaaa agaagaaatt cgaaacaata tcaaaacagc tgattttatc
     8401 acactgactg ttggcggtaa tgatttgatg aaagttatcc aaaataattt attcgggtta
     8461 acggtcaatt cctttaaaaa gccactgaaa aactatcagg aaaatgtcac agaactattg
     8521 gaagaatttc gatccctcaa taaaaccgca cctatttaca ttttaggcat ctacaatcca
     8581 ttttatttga actttcctga gatcactgac atgcagacaa ttgttaacaa ttggaacaaa
     8641 ggaacagaaa cggtgacaaa aaaaatgccg aactgctact ttatcccaat caatgatttg
     8701 ctttatcaag gattgaatca ggaagtaggt gtcacagaag aaggaacaga tcaaacaact
     8761 agcacgacag aaaatctaaa tggcatcaaa aataatgtgc tctatgaaga agatcatttc
     8821 catccaaata atttaggtta tcaattgatg gcaaatgcag tgagagatca gctgatcgag
     8881 acacaaaacc aatggttaga gaaggaggat gatcaataaa catgaaaaca agatctgacg
     8941 tatcttcaaa caaaacaaag aaaacaaatt actggaaatt cgccttcctt atccttcttg
     9001 gggtagtact tggttcgacc gtatttttag gcagccgtat ttttgctaat cgggaaccag
     9061 aactcccaga aataccagct cttacggaaa gacaaggaga tcctgtctta acgatcaatt
     9121 caaataaaga aaaagtcaat caaatcatca gctttttcct tagtgagtat caaaaagata
     9181 gtgatattga atataaattt tatttggaaa atgaagcact actcaatggt actttcgaag
     9241 tactaggttt tcctatcgat ttctatttat attttgatcc gtatgtgatg gaaaacggaa
     9301 atgtccaact aaaagctaga agtctttcta tcggaacatt gagtttgcca atcaaagatg
     9361 tgatgaatat gatcaagaga aactataaat taccagattg gatcgaagtc aatacagatg
     9421 atctgactat catgcttagg ttggatcaat tccgaatgca aaacgggatg tatattaaag
     9481 cagataaaat cgacttagta aatgatgaca ttcggtttag tctatatttg ccaaaagata
     9541 cctctgatgc ttcaaacaac tcaaatacca acaaaactag caccagcagt actgaaagca
     9601 agacaaaaga aaataaaaaa tcatcggatg agtagtatta gagggggaat cataatggaa
     9661 cgagcaatat ttgcaggagg ctgcttctgg tgtatgatcc agcctttcga cacgcttcct
     9721 ggtatccata cagtgatgtc aggatatact ggagggcatg taccagatcc gacttatgaa
     9781 caagtaaaaa gccaaacgac tggacataca gaagcagtgg agattatcta tgatccaaca
     9841 ttgatttcat atgaacaatt agtagaactt tactggcagc aaactgatcc aactgacgct
     9901 ttcggacaat tcgaggatcg cggtgacaat tatcgcccgg tgatctttta tttgacagaa
     9961 gaacagcgga tcattgctga aaaaagtaag aaacagttag ctgaaagtgg acgtttcgaa
    10021 cagccaatcg ttacaaaaat cgaaccagcc caaccatttt atctagcaga agaagaccat
    10081 caagagtatt ataaaaagca tcctgaaaat tttaaaagaa accatgcacg ccgggctgcc
    10141 tttatcgaag aaaattggag gaacgaaggg tgaatcgaag cttttttcat tatttaatga
    10201 cactgcgagg cggtggcaca catgatgctt tatctgtttt cgctacagaa gccggtaaag
    10261 acatccaatt tcctaagcac agctctagct acgaagaaat ttctaattat ctggaactga
    10321 atgtcgacta tttgccgtcc atggatatct ttgacgaagc atgggaaaaa tatttagaaa
    10381 ataatcatga catataagag atagttttgt actttatgat caaaaaagtt ttttgtccaa
    10441 tagcctaatt gaaagaatta tttttatttc agctatctag tcgcattttt ttgatatttt
    10501 tcttataata aagaaagaat gaaaaaaaga gggatggatt gatagagatt gacaaaaaaa
    10561 caacgctata ttaatcgctt ctggcttgta ttcaaatact tacttgtttc tgtattcctt
    10621 gcgttcatgt tgcggggatt tttattcatc ccggtaccag tggaaggcaa ttcaatggaa
    10681 aacgtgttga agcaaggtga tatggttgtg atggaaaaat tttcggagat cagacgattt
    10741 gatattgttg tttttcaatt agcagatggc acgatttata tcaaacgagt aatcggtctt
    10801 ccaggagaaa atgtcagcta ccaaaatgat caattgaaga tcaatgggaa agtagttaag
    10861 gaaccttatc taactaaaaa cctgaaatca gatcatgcaa atgcatccta tacgacggac
    10921 tttacactac aagagctaac gggacaatcc aagcttccgg aagataatta ttttgtactt
    10981 ggagataatc gaagagtttc aaaagatagt cgttcgtttg gcacgatcaa taaaactgat
    11041 attctaggta aagcaagatt tgtctattat ccacttgatg aaataaaatg gatccagtga
    11101 gaaacaataa agcgtgcagt ctgttgagac tgcacgcttt attgtttaat ccaaaatcag
    11161 tttactacct tagtacgtaa aatcaaacag ctcgtttaaa cacttttcta gcctctaaag
    11221 ttttgataaa tgaataaaca accattattt gaatagggat ttggatcata ttcctgatga
    11281 atctacctag aaaaattact ttgaaatctg caccaaacaa aacagacatc agccaagaat
    11341 tgataaaaag gctgactggg atcataatca ataattgggc agcgatgacg gaaggcaggt
    11401 ttatcttttt atgatataaa aataagccat taataaatcc accaaggaaa gccgtgataa
    11461 gaaaagcagc ttgaaacgtt cctgaaccaa atatcgtgaa atttaaagtg ttcgacaaca
    11521 tttcaagcaa accagcccag atcggtccat atagataacc cataagcgcc atacttaaaa
    11581 atccgaatgt gatttgaaaa taagcaggac caatcgctat cttgtataag atgacatcaa
    11641 gggctaataa aagagcagag gtcgacaaca atcttgcatt catttcgggc aatctaaaaa
    11701 cgtcttttgc aatcaaagtg ttcaaaatat tctctccttt gtcagttaat aataaaagga
    11761 taccataaaa tcaccaatgt gtcatgacac attggtgatt tacatacact ggcatctaac
    11821 aattaaaaaa agggtgagaa gactgctttt ataaactgta aaaaagagat tgtacgaata
    11881 aaaaaaatag aggcggagaa tacttatcgt atcatccgcc tttgtttttt tgttataaaa
    11941 aacgtcagat tagttatctg cttacatctt catccatacg ggttctaatg tatttccgtc
    12001 tagatcttgg acttctaatg aaaacatttc ttcttcaggc attcccatat ctacttcgtg
    12061 gaaagtacca ccattttctt ttgcaatttg agcaaatttt tttacttcat ccgcattttc
    12121 aacactaaac gaaatcaaag caccacttgt ttttttatta tcagctattt ctttatcttt
    12181 tataaatttt ttataaaaat catgagagag aagcattatc caaaaagtgt catcccatac
    12241 cattgaacca gcttcttcag tagaaaattc ttcatttttt ttaaaaccca gcttttcata
    12301 aaaagcaacg gaacgattga catcagcaac aggaaaatta acaaaaacca tactattcat
    12361 ttgtttcgtc tcctttctgt tttgttcgtc tatcatctct tatttaggaa acgctgtcaa
    12421 aaatttagat tcatatatag aaaccaaaat aaaaatttgc atcatcaaaa aagtgaagat
    12481 gtgatagaat gaggactggt tcactttcac ttaactaata gatggaattt ctttataata
    12541 aaaaagtgaa tttatattga aaaagaaaaa aacaagtaaa gccggggaat attccggtat
    12601 gaaaggaatg gagagaacaa tgaccatcca atggtttccg ggacatatgg caaaagcccg
    12661 acgagaagtt tctgaaaaaa tgaaatatgt ggacatcgta tttgaattgg tagacgcacg
    12721 attaccttta tcttctcgta atccaatgct agatcagatc attcagcaaa aacctcgcct
    12781 tgttttattg aataaagcgg atctggcaga tccacaacag acaaagctgt ggcaagaata
    12841 ttttcgtaaa caaggccatc ttgcattagc tatcacggca caagaaagta aaggaattaa
    12901 aggtctagta cctgcggcta aagaagcatt gaaagaaaaa cgggcaagag atgctgctcg
    12961 ggggatcaag cctcgcgcta ttcgggcaat ggtcttaggt attccaaatg ttgggaaatc
    13021 tacgttgatg aatcgactag taggcaagaa aattgcacag acaggaaata agcctggcgt
    13081 aacaaaaggt cagcagtggc ttcgtttagg taatgagttg gaattgttag acacaccagg
    13141 gattttatgg cccaaatttg aagatgaaga aatcggcaaa aaactagcgc tgacaggcgc
    13201 gatcaaagac cagcttgtcc atttagatga tttagcgatt tacggattag acttttttgc
    13261 ccgatattat tcaggaagaa tcagcgatcg ttatggttta tcaatcgagc aagaagaaaa
    13321 attggcaccg gaattactga tggatattac agcaaaacgt gggtataaag aagactatga
    13381 tcgtggcagc gaattagtcg tgcatgatat tcgtcaagga aaacttggac gatacacact
    13441 ggatcgttgc gaagaaatgg agcaaaaaag tgatgactga atccatccaa agtatcaaag
    13501 aacgattgaa aagcatacag agaatagatg atcctacact agaatcatta agaaatgatc
    13561 cacgcaaagg cgtgcagcaa gcactggctt cttttgaacg acgattgaaa aaggaagcat
    13621 taattaagga aaaatatgaa gaaatgtttt gctttgaaaa gcaagggtac gcacaaggtc
    13681 accaatggat tgccggcatt gatgaagtag gaagaggacc attagctgga cctgtcgtgg
    13741 cagctgcagt tatcttgccg aaaaatgaga tcatattagg gctgaatgac tccaaacaat
    13801 tatcagagaa aaagcgagaa cttctttatc aacaagttca agaaaaagcc ctggcaatcg
    13861 ggatcgggat cgttgatcag cagacaatcg atgatgtgaa tatttatgaa gcaagtaaat
    13921 tagcgatgat ccaagcagta gaaaaattgt ccattgtacc aagctatttg ttgatcgatg
    13981 cgatgacctt ggatttgcct attcagcagg aaaaaataat caaaggggat gcacgatctg
    14041 tgtcgattgc tgctgcaagt atcattgcta aagtatatcg agaccaattg atgaaagaat
    14101 atgacgtgct ttatcctgga tatggtttct cgcataatgc aggttatgga acaaaggaac
    14161 acttagaagg acttgaacga caaggaatta cgccaatcca tcgtaaaagt tttgcacctg
    14221 taaaaaaata tttacaataa aaaacagccg cttttacgta tcttattaga aagagagacg
    14281 aaaggcggtt ttatgatgta tcaaatagaa gaaaatttat tgaaacttgc ttatacaaaa
    14341 ggaatcagta gtcaaggaaa atgggcactt gctaactgga tgatgcagta tccttataaa
    14401 gaaatcggat ttgaagacat cattaagata ggtaaaataa ccaaacaccg ggagctgttt
    14461 cgcaaaagtt ggcaggaaat tcacgctaac tggggcaaaa tccaatcgaa acagtcgttt
    14521 atcacttgct ttgatcccaa atatccccct cagctgcttc acttgaccta tccgccaatt
    14581 gtactgtttt ataatggtga tctatcttta ctttcttgta acatgttaag cgttgttggt
    14641 ggaagacaca cttctgcttt agccaaaaaa acagtttatt atttactaaa accagtgata
    14701 gaagctggat atgtgatcgt cagtggctgc gcgaaaggga tagatacata cggtcaccaa
    14761 gcagcaatct ctcatggtgg acggacaatc gcagtcattg gaacagggat agagcaagtc
    14821 tatcctgctg aaaatcgtga cttgcaagag gtgattgcaa atgatcatct tcttttgagt
    14881 gaatatcctc ctcaatccgg cccgaaaaag cattgttttc caatgagaaa tcggattatc
    14941 gcagctttgt ctaaaggaac atgtgtcttt gaagccaaga aaaaaagcgg ctctctgata
    15001 acagcacagc aagcattgga tcttggaaga acagtttttt ctgttccagg aaatatttta
    15061 acagaacatt ctaccggatg tcatcatttg atccaagacg gtgcagtttg cacggtttcg
    15121 ggtgaagata tcttggcaga atttaaagaa taacaccata cttttcattt gcttttcttg
    15181 acaaacgttt tctgaatgga tatgattagc tacgatttgt atgaatcctc ttttaatagt
    15241 aggaacacga caatggaaag gagtccattc agtaatggcg tataaatatt tagtgattgt
    15301 agaatcacct gcaaaagcca agacaattga gaaatatctt ggacgaaact ataaagtaat
    15361 ggccagtgtt ggccatataa gagatttacc gaaaagtaaa atgggtatcg attttgaaaa
    15421 caattatgaa ccccattata tttctatacg cggaaaaggc gatgtcatca aaagcctgaa
    15481 agccgcagca aaaaaagctc aaaaagttta cttggcaagt gacccggata gagaaggaga
    15541 agcgattgct tggcatttag cgtacctact tgggttggat ctgaaagaaa aaaatcgggt
    15601 ggtcttcaat gaaatcacaa aagacgcagt caaagcagct tttaaggaac caagaacgat
    15661 cgatgtagat ttagtagatg cacagcaagc tcgtcgtacc ttagacagaa tcgttggtta
    15721 ttcgatcagt cctattctct ggcgtaaggt caagaaaggg ttaagtgcag gacgtgtcca
    15781 atctgtcgct ttaaaaatta ttattgaccg tgaaaaagag atccgagaat ttgttccaga
    15841 agaatattgg agcatcgacg gtaattttaa aaaagctcgc aagaaattca aagcaaattt
    15901 ctggggaatc gacggtaaga aaaagaaatt accagatgca caaagtgtaa aagaagtcac
    15961 tgctagaatt gatggaacag acttcgaagt taaaaaagta gaaaagaaag agcgcaaaag
    16021 aaaccctgcg aatcctttca ctacaagtag cctgcaacaa gaagctgccc gtaagttaaa
    16081 ctttcgaaca agaaaaacca tgatggtagc acagcaatta tatgaaggaa tcactttggg
    16141 taaacaagga acagtcggct tgattacata catgcgtact gattctaccc ggattgccga
    16201 tacagcaaaa gcagaggccg cagcatttat tgaagatacg tatggaaaag aattttctag
    16261 acatgatcac cgaaagatca aaaatgctca aggcgcacaa gatgcccatg aagctgtgcg
    16321 tccaacgagt gtgcttcgta caccagatga actcaaacaa tatttagata aagatcaatt
    16381 gaaactttat acattgatct ggtcacgttt tgtggctagt cagatgacac cagctatttt
    16441 agatacaatg aaagtgacat tagaacaaaa tggtgtcatc ttcattgcga acggttcaaa
    16501 aatcaaattc aaaggattca tgcaagtgta tgtggaaggt agagatgacg gcaaagaaga
    16561 gaaagaaaat attcttccag aacttgaaga aggcgatgta gtccaatctg ttgatattga
    16621 accaaaacaa cattttactc aaccaccagc acgttttagt gaggctacgt tgattcgtgc
    16681 actagaagaa aacggggtag ggcgaccttc cacttatgca ccaacacttg atacgatcca
    16741 aagacgctac tatgtaaaat tgacacaaaa aagatttgag ccgactgaac taggagaaat
    16801 tgtcaattca ttaatctgtg aattcttccc tcaaatcgtc gatatccatt tcacagcaga
    16861 aatggaagga gatttggata aaattgaaga aggcacggaa gcgtgggtca aagtggttga
    16921 tcgtttctat aaaccgtttg aaaaagaact gacgaatgcg gaagaaaaaa tcgaaaaaat
    16981 tcaaatcaaa gatgaaccag caggattcga ttgtgatgtc tgtggacatc cgatggtgat
    17041 aaaattaggg aaatatggga agttttatgc ttgcagtaat tttcctgatt gtcggaatac
    17101 gaaaccaatc gtaaaagaaa tcggtgtgac ttgcccagta tgtcatgaag gacaagtcat
    17161 tgaacgaaaa tctaagaaaa acagactatt ctatggttgt tcccgtttcc cagaatgtga
    17221 attcacttct tgggataaac cagtgggcag aaattgtcca aaatgtgacg gatatctggt
    17281 cgagaagaaa gtcaaaggcg gtaaacaagt agtctgtgta aatggagatt acgaagaaga
    17341 catccaaaaa taatagaaaa gaggttcttt cattgaaaat ggtaaatgtt gttggagcag
    17401 ggcttgccgg aagtgaagct gcttggcaga tcgcacaagc aggagtccct gtccgtttat
    17461 atgaaatgcg tccagtcaaa tcgactgagg cgcatcacac aagtaatttt gctgaactag
    17521 tatgttccaa ttcattaaga ggaaacagtt tggctaatgc agtagggtta ttgaaagaag
    17581 aaatgcgccg attgaattcg gtagtaatca cttcggcaga tgaaacagca gtgccagctg
    17641 gtggtgcctt agctgttgac cgcgattctt tttctgaaac aattacccga aaagtcaaag
    17701 agcatccatt agtaacagtg ataaacgaag aaattactga aataccggaa ggaatcaccg
    17761 tagtagcaac aggacctttg acttctcatc cattagcaga aagcatcaaa gcattcaatg
    17821 gttcagatgg tttttatttc tatgatgcag ctgcaccaat cgtagacaaa gctacgatcg
    17881 atatggataa agtatatttg aagtcccgct atgacaaagg agaagcagct tacttgaact
    17941 gtccgatgac agaagaggaa ttcaaagctt tccatgaggc actaatcaat gccgaagtgg
    18001 cagaacttaa atcttttgag aaagaaaaat attttgaagg atgtatgcca attgaagtaa
    18061 tggcacagcg aggattcaaa acgatgcttt tcggacctat gaaaccagtt ggattggaag
    18121 atcctaaaac tggcaaacgt ccttatgctg ttatccagct gcgtcaagac aatgctgcag
    18181 cttctttata caacatcgtg ggctttcaga ctcacttgaa atggggcgag caaaaacgtg
    18241 ttttccggat gattcctggg ttagaaaatg ctgaattcgt tcgctatggt gtgatgcacc
    18301 gaaacagctt tatgaattcg ccagaattgc tgaaaccgac ttaccaatca acgaaacgcg
    18361 aagatctgtt ctttgcaggt cagatgactg gtgtagaagg ctatgttgaa agtgcagcga
    18421 gcggactact tgctggaatc aacgccgcac gcttagcaaa agaaatggaa ccagtcgagt
    18481 ttccacaaga aacagctatt ggaagtatgg cttactacat tactcatgcg gaaggaaaac
    18541 atttccaacc gatgaatgcc aactatggtc tgtttcctga actgccagag cgcattcgag
    18601 acaaaaaagc aagatatgaa gcaattgcac aacgagcttt aaaagctaat gaggcaataa
    18661 aaacagaatt agaaaaaact gcaatcccaa atgagtaagg aaactccatg aagagggtga
    18721 gacggatagt ctcgctcttt ttcttgcgtt tttcttaaga atttctcaaa caaaatgtga
    18781 ggaattgcgc caattgtgaa caaacttaga aatattggtt aaattctgac aatttatttg
    18841 tctttttata aacgctgtgc taaattattc tctgggacaa aaggaaggtg agaaaatgac
    18901 agaagccacg tgggaacaaa aatttttgcg ttatttgatt gtcgaaagag gatattcaga
    18961 aaaaacgaaa gaagcatatg aagaagacat tctccatttc aaacattttt tggaggaatc
    19021 tggagacgct gatctgctga aggcggaata ttttacggtt cgtgtctatt tgagtgcatt
    19081 agctgatcat cgtcctagct atagcagaaa ttctatcagt cgcaagatag ccagcctacg
    19141 ttcgttttat cagtatcttc tcaaagaaga agtgataaaa gaaaatccat tttcttacgt
    19201 tcatctcaaa aagaaaaatt tgagactgcc acgttttttt tatgaaaatg aaatgcaagc
    19261 actttttgac agcgtagcag gagatagtcc tttggatttg aggaaccgcg ctttactgga
    19321 agtcctttac gggtcaggca tccgtttaag tgagtgtagc agtttgtcgg tatcagacat
    19381 tgattttgat tcagaggtca tgttgatcca tggtaaaggg aacaaagaga gatatgctcc
    19441 tctaggttct tttgctcaag atgctctgca agaatatttc agggaaggcc gccaggtatt
    19501 gatgacaaaa tatcacgaag agcatgatat cgtttttgtg aatcatcatg gaaaaccaat
    19561 cacgcctact ggaattgaat atgtcttgaa tcaaatgatc aaaaaaagca gtttggatag
    19621 tgatatccat cctcacatgc tgcgccatac atttgctact catttattaa ataatggggc
    19681 agatttgcgg acagtccaag aattgctagg acatgccaat ttatcgacta cccagatcta
    19741 tgcccatgta acaaaagaaa gtttacaaaa aaactatcgt tctttccatc caagagcgta
    19801 aaaataagga aaagaacaaa tttaggagga aacaaacatg gtcgaatcac catttcattc
    19861 aaccactatc tgtgccgtcg aaaaagacgg gaaatttgct atggctggag atggccaagt
    19921 aacaatgggt gaatctgttg tcatgaaagg cactgcaaag aaagtacgac gtatctacaa
    19981 tggagaagtt gttgtaggtt tcgccggaag tgttgcagat gcgtttactt tagaagaaaa
    20041 atttgaaggc aaactaaacg aatataacgg gaatctacaa cgcgcagctg tcgaattagc
    20101 tcaagaatgg cggacacagc aatctatgca aaaacttgaa gcgatgctga tcgtaatgaa
    20161 tgataaagaa atgcttcttg tttcaggtac aggagaagtt atcacaccag atgatggtat
    20221 cttagctatc ggatcaggag ggaattttgc gttggctgca gcccgagcaa tgaaaaacta
    20281 tgctcaaaac gacatgagtg cgaaagaaat tgcagaaaat gcgttaaata ttgccgcaga
    20341 tatctgtatc tttactaatc ataatattat cgtagaagaa ctgtaagagg tgagtagata
    20401 tgtatgaatt aaaacaaaca ccaagacaaa tcgtaagtga attagatgaa tatatcgtag
    20461 gacagcacgc agcaaaaaaa tctgttgccg ttgctttgcg taaccgctat cgccgtttgc
    20521 agttagatga aaaaatgcaa caagatatta caccaaaaaa tatgctgatg atcggaccta
    20581 caggggtcgg taaaacagaa atcgcacgac gtttggcaaa aatcgtcaat gcaccatttg
    20641 tcaaagtcga agcaacaaaa tttactgaag tcggttatgt cggaagagat gtagaatcaa
    20701 tggttcggga tttagtagaa aatgcgatcc aaatcgtaga aaaagagcag tacagccgtg
    20761 tatacacaag tgctaaaaaa aatgcagaaa aacgtttggt aaaaatcttg gtacctggta
    20821 tcaaaaaaga acagaaacaa tccactaatc aatttgaaca aatgatgaat ctttttaatg
    20881 ctagtcagca aaataccgct gaaccgcaag aagaagtgac agaagatatt cgaatcaatc
    20941 gccgtacagt cttggaacaa ctacaaaagg gtttactgga tagtcgtgaa gtaaccattg
    21001 aagttgaaga ccaaaagaaa cctgcaccaa tgatgaacaa tggattggag caaatgggga
    21061 tcgacctaaa tgaaactcta ggtgctttga caccgaagaa aaaagtggaa cggacggtaa
    21121 cagtcaaaga agctttagag ttattgatca aggaagaatc agcaaaatta gtcaaggatg
    21181 ctgatatcca tagtgaggca atcaaattag cggaagaaag tggaattatt tttatcgatg
    21241 aaatcgataa gatcacttct aaatcacagc aatctggaga agtatccaga gaaggcgtcc
    21301 aaagagacat attgccaatt gtcgaaggtt cacaagtaaa cacaaaatac gggatcatcc
    21361 aaacagatca cgtcctattc attgcttcag gagctttcca tttgtctaaa ccaagtgatc
    21421 taattccaga acttcaagga cgcttcccga tacgggtaga attagatgat ttgacagctg
    21481 aagattttgt gaagattctg accgaaccaa ataatgcttt agtaaaacaa tacgtcgcgt
    21541 tgatcggtac agaaaatgtg tcagttacgt ttacaaaaga agcaattgaa cggatcgctc
    21601 aaatcgcttt cgatgtcaac cgtgacacag ataatatcgg cgcacgcaga ctgcatacca
    21661 ttttggaaaa actactagaa gatctattat ttgaagcacc agatatgcaa atgggagaaa
    21721 taacgatcac agaagcatat gtggatgaca aacttggctc aattgcggca aatgaagatt
    21781 taagtcgcta tattttataa aaaatcggag gacgacaatg acagacttgc taacgaaaac
    21841 ccgcaagata aacacacttt tgcagcaaaa gaatactttt gacatgcaag cagatttgcc
    21901 ttacgataaa atggctgtca cactaggtgg tattcttgac agcaacacct atatcatagg
    21961 aagtgacgga gtattactag gttataatga acgtcacgat gtgaacaatg aacgaatcaa
    22021 aacaatgttt gttgagaaac aatttcctga atcttatact gatacagtgg cacagttgat
    22081 gaaaactgaa gctaatatcc caattactag tgatattact gcatttccgg tagagtcaag
    22141 agagaaatat ccatttggtc tgacgactgt cgttccgatc tttggagctg gcgaacgttt
    22201 gggtacgatt atcttatctc gtatggaaca atcgtttgca gatgacgatc tagtcttagc
    22261 agaatatgga gctacggttg tcggtatgca gatcctttat cagaagtctc gaagcatcga
    22321 agcagatgta cggagtgcaa cggctgtcca aatggcaatc aacacattat cttatagcga
    22381 attgaaggct gtacaagcta tctttgaagc attggatgga gatgaaggtc gtctgactgc
    22441 ttctaatatt gccgatagta tcggcatcac tcgttctgtg atcgtcaatg ctttacgaaa
    22501 attggaatca gctggaatca ttgaatctcg ttcgttaggc atgaagggaa cttatttaaa
    22561 agtattgaat tcccgtttta aagacgagtt agcaaaacac agttattaga agtaagggga
    22621 ctggggcaga tagaaatgtt tgttccagcc ttcccatttt aaaaagtaag tcgaagttgg
    22681 aggaatggca atgactgtta ttattcaaaa tgaccagctg atcgccgaaa tcgctgaaca
    22741 cggtgcggaa ttgatcagtc tgaaatcaaa agaacatggt ttagagtata tctggcaagg
    22801 tgatccagcg tattggggca gacatgcacc ggttttattc ccttttgttg gacgtttaaa
    22861 agatgatcag tatgtttatc aagggaaaac atatcaaatg gggcaacacg gatttgctcg
    22921 ggatatggat tttgaagtca ttgaacatgg acaagaaatg gctagtttca tcttaaggag
    22981 tacgccggag acattagaaa agtatccatt tgattttgaa ttagtgatca gctatgaatt
    23041 aggaggagac ggcatcacgg ttcattatca agtggcaaat accggtgaaa aagaaatgtt
    23101 cttttctatc ggtggacatc ctgctttcaa tgtacctctt gaagaaggat tgtcatttga
    23161 agatttctat ctggcatttt ctccattgaa atcaagatta cgcctaccat tgaaaggccc
    23221 attcatcgat atggatcaaa agacgttagg tcagacaaat acgaatctgg ctttgaatcg
    23281 tgaacttttt gagcaagatg ccttggtttt tgaaacaagg ggtctaaatg cgtacgccat
    23341 tcgaagtgaa aaatcttccc atagcgtaac tttaagctat aaagatatgc cttatgtagg
    23401 gatctggtct ccttatccaa aagaagcgcc tttcgtttgt atcgaaccgt ggtgcggaat
    23461 cgctgacacg gtgaacagta gtggaaactt gatggaaaaa gtagggatca atcaactagg
    23521 tgcccatgaa atcttcaaga caaaatattc catcacagtg aagtaagagg ttgtgaccga
    23581 gaagttagca gggaacaccg tttaccaagg tgtgtaaaaa agctatcctg taagtaataa
    23641 gggagtgtga catcg
//
LOCUS       DAFBSV010000041        23579 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.042, whole genome shotgun sequence.
ACCESSION   DAFBSV010000041 DAFBSV010000000
VERSION     DAFBSV010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23579
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.042"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            45..677
                     /locus_tag="LLB18_001502"
     CDS             45..677
                     /locus_tag="LLB18_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBK5244509.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(679..1584)
                     /locus_tag="LLB18_001503"
     CDS             complement(679..1584)
                     /locus_tag="LLB18_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBK5244510.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(1669..2328)
                     /locus_tag="LLB18_001504"
     CDS             complement(1669..2328)
                     /locus_tag="LLB18_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBK5244511.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            2644..3588
                     /gene="mvk"
                     /locus_tag="LLB18_001505"
     CDS             2644..3588
                     /gene="mvk"
                     /locus_tag="LLB18_001505"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HBK5244512.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            3581..4558
                     /gene="mvaD"
                     /locus_tag="LLB18_001506"
     CDS             3581..4558
                     /gene="mvaD"
                     /locus_tag="LLB18_001506"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HBK5244513.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            4571..5656
                     /locus_tag="LLB18_001507"
     CDS             4571..5656
                     /locus_tag="LLB18_001507"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HBK5244514.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            5653..6717
                     /locus_tag="LLB18_001508"
     CDS             5653..6717
                     /locus_tag="LLB18_001508"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HBK5244515.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(6966..7769)
                     /locus_tag="LLB18_001509"
     CDS             complement(6966..7769)
                     /locus_tag="LLB18_001509"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HBK5244516.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(7789..8631)
                     /gene="kduI"
                     /locus_tag="LLB18_001510"
     CDS             complement(7789..8631)
                     /gene="kduI"
                     /locus_tag="LLB18_001510"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HBK5244517.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(8647..9654)
                     /locus_tag="LLB18_001511"
     CDS             complement(8647..9654)
                     /locus_tag="LLB18_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBK5244518.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(9661..10305)
                     /locus_tag="LLB18_001512"
     CDS             complement(9661..10305)
                     /locus_tag="LLB18_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HBK5244519.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(10405..11163)
                     /locus_tag="LLB18_001513"
     CDS             complement(10405..11163)
                     /locus_tag="LLB18_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBK5244520.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(11290..12441)
                     /gene="fucO"
                     /locus_tag="LLB18_001514"
     CDS             complement(11290..12441)
                     /gene="fucO"
                     /locus_tag="LLB18_001514"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HBK5244521.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(12523..12834)
                     /gene="rhaM"
                     /locus_tag="LLB18_001515"
     CDS             complement(12523..12834)
                     /gene="rhaM"
                     /locus_tag="LLB18_001515"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HBK5244522.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(12836..13681)
                     /gene="rhaD"
                     /locus_tag="LLB18_001516"
     CDS             complement(12836..13681)
                     /gene="rhaD"
                     /locus_tag="LLB18_001516"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HBK5244523.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(13695..14951)
                     /gene="rhaA"
                     /locus_tag="LLB18_001517"
     CDS             complement(13695..14951)
                     /gene="rhaA"
                     /locus_tag="LLB18_001517"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HBK5244524.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(14948..16408)
                     /gene="rhaB"
                     /locus_tag="LLB18_001518"
     CDS             complement(14948..16408)
                     /gene="rhaB"
                     /locus_tag="LLB18_001518"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HBK5244525.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            16561..17430
                     /locus_tag="LLB18_001519"
     CDS             16561..17430
                     /locus_tag="LLB18_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HBK5244526.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(17556..18455)
                     /locus_tag="LLB18_001520"
     CDS             complement(17556..18455)
                     /locus_tag="LLB18_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5244527.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(18620..19444)
                     /locus_tag="LLB18_001521"
     CDS             complement(18620..19444)
                     /locus_tag="LLB18_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBK5244528.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(19455..20750)
                     /locus_tag="LLB18_001522"
     CDS             complement(19455..20750)
                     /locus_tag="LLB18_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HBK5244529.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(20766..21245)
                     /locus_tag="LLB18_001523"
     CDS             complement(20766..21245)
                     /locus_tag="LLB18_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HBK5244530.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(21251..22279)
                     /locus_tag="LLB18_001524"
     CDS             complement(21251..22279)
                     /locus_tag="LLB18_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HBK5244531.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(22296..23402)
                     /locus_tag="LLB18_001525"
     CDS             complement(22296..23402)
                     /locus_tag="LLB18_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBK5244532.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
BASE COUNT         6779 a         5200 c         4239 g         7361 t
ORIGIN      
        1 ttcccgcttc tttgctatac taaagaaaaa cgaggtgaac ccacatgaaa aaaatcgaac
       61 ctattccacc ttctcttcct cttcttacaa agggagagtt ttatttagaa gatgaggaga
      121 tcttctctgg tcttctgatc aacgggggtg accaaagcta tctcgatgcc aaaaatatgg
      181 tattaagaga gagtcatatc caaaaactta cgatgcaaaa aacagtttta cgtcattttg
      241 aatgcagtaa tgtcattttt gaaaaatgtg atttttccaa tctggagtgg attggtggca
      301 gtttccacca agtcgtgttt catcaatgta aattaacagg tacgaatttt gccgaaagtt
      361 atcttcgaga ctgtactttc actgattgta ttgcttcgat ggcttccttt agtagtacaa
      421 acttgaaagc tgtctccttc gatcattgtc aattagaaga cagcgaattt tatgaggtca
      481 cttggaaaaa cctttttttg tctgacaatc agttgaccgg ttcgaactgg tttcgaactt
      541 ctctgaaggg attagacttt acgactaatt tcttcacagc aatcgcttta tctcaagatt
      601 ctttggcggg actaatcgtc aaccaagagc aagcacttgt gatcgcccaa gcccttggtt
      661 tgcagatcaa agactagatc aacgaatccg ccgccacagt gcaataagca tccaaataga
      721 taagaccaaa ctgatgatca aggcgattcc ccatccgaaa acggaatggg taaagggtaa
      781 ctggagattc attccgaaga atcctgtcac aatagttgga acggtcaaga tcagcgacca
      841 gaccgtcaaa aatttcatcg tgtcattcaa gttgttattc agcaaattat tataagtgcc
      901 agagagctgg tctaaaatct gcgaagctaa gttcgtcatt tcaactgctt gtcgtgcttc
      961 gatcagcgca tcgtccaact cttctttttc cttttctgac aacttgcgat aaatagccaa
     1021 tgccttgatt tgttctaaaa gtactacatt ttgttttgtt cctgtaacta agtaaaccaa
     1081 accgatctct aaatctgaaa gttgcagcag attcttgttc gttgtttttt ctcttaattt
     1141 cagattaagc cgctgacgtt cactattcac ttcctcgatt aaaggaaaaa aggaatcaga
     1201 aatcaaaaac aatgtacgaa acaataaact gtatacactc atgtctggca ttcgttccaa
     1261 aagcgatcga attagtcgaa tcacgtactc ggtattcggc gtggtaaatg taaacaaacc
     1321 gtcttctttt aaaataaaag cgataggact agtttcataa tgattatcga ctttttgctg
     1381 gtgcggaaca tttgatacaa gcagtaacgc ttcatcaaaa gaatcgtact ctacgcgcgc
     1441 ccgttcattt ttatctagag aataagtcag catctcgtca ctaatgccat attcttcttt
     1501 taagttttta acagctagca catcgttttg ctgtacattg atccaaaaat tacggtcttg
     1561 attaaaatag tgtttttccc gcatactcta tcctcctgac atttgtttcc agtataaaga
     1621 aaaaagtcgc tcaaataaag gtttaccctt tatttgagca actgtaaatc aaatggctac
     1681 tttggtttgg cgaatctctg ctaatttttc ttcgatcatt ttcaagactt cttcttttgc
     1741 ttgaggatct tccacaaaat tatagcggtc tccatcgatt tggatttttg gactttcttt
     1801 gtattcttca taccattgat cgtaacgtct gttcaattct ttgtaataat cgtatagact
     1861 tggatcaaag gacaattgtt catacgaacg accacgtttt tcgatacgct ccaacatcgt
     1921 atcaaaagat acacgaatat gaactaataa atccggatgt tttttatggg cagcataggg
     1981 aagttcttcc atcatgtttt ccagcagttc atcatacaca cgaacttctg tttctgttgc
     2041 tcttcctaga tctgcattta gatggaaaag cagtgaatct tcataaatcg aacggtccaa
     2101 tacattattg tcatctttca ttgcttgttt gatgcttgca aaacgtttat tcaaaaaata
     2161 aatttgcagc aaaaaagcat actgttcagg gtttgcataa aataagggca agacttcatt
     2221 atcatcaatc gattcataaa atgcctgact atcaaagtgt tcagccatca tttctgttaa
     2281 acttgatttt ccggcaccaa ttgtacctgc taaaacgatc acgctcattt acctccagct
     2341 cacttcatca ctaaatattg tgtttaactc caaccttttt aaatataccc ccaatatcta
     2401 gtagtgtcaa ttgtattttt ttctagtcaa agaagaaaaa aagtcaaaaa attcttaaga
     2461 aaaaagtgtt ttttctttag aaaacgtatt cttagtttta cttctgagat ggttttagta
     2521 aaataaagga ggaatgtttt ttgagaccct tagtggacaa aaaaattcgt gaagcagcgc
     2581 aactcgtttt gggcgcttta ttttttgctt aaaaatcact tttacgtgag aaggagttag
     2641 attatggcaa actatggcca aggagaatca agcggaaaga tcatattgat gggcgagcac
     2701 gcggttgttt atggagaacc agcgattgcc tttcctttct atgcaacaaa agtcaccgca
     2761 ttccttgaag agctggatgc aatggacgat caactggttt cttcctacta ttcaggaaat
     2821 ttagccgaag ctcctcatgc attaaaaaat atcaaaaaat tattcattca cttaaaaaaa
     2881 cagcatgaca tccaaaaaaa cttgcaactg accattgaaa gcacgattcc tgctgaacgt
     2941 ggaatgggat caagcgctgc agtcgccaca gcagtcactc gtgcttttta tgattactta
     3001 gcatttcctt tgtctcgtga aatactatta gaaaatgtcc agctttcgga aaaaatcgcc
     3061 cacggtaatc ctagtggaat cgatgcagcc gctactagca gcttgcagcc gatttatttt
     3121 acaaaagggc atcctttcga ctacttttct ttgaacatcg atgctttttt gattgtcgct
     3181 gatacaggaa tcaaaggaca aacaagagaa gccgtcaaag atgtcgctca cctctttgaa
     3241 acccagcctc atgaaactgg acaaatgatc caaaaattag gatacttgac gaagcaagca
     3301 aaacaagcaa tcattgaaaa ttcaccagaa acgttggcac agacaatgga tgaatcacaa
     3361 tcacttctgg aaaagctgac aatcagcaat gattttctta atctattgat ccaaacagca
     3421 aaagataccg gggcattggg tgccaaatta actggcggtg gacgcggtgg ctgtatgatt
     3481 gcattagcac aaacaaaaac aaaagcccaa gaaatcagtc aagcacttga agatgcgggt
     3541 gctgctgaaa cttggataca aggattagga gtacatacct atgtttaaag gcaaagcacg
     3601 cgcatatacc aacattgctc taatcaaata ttggggtaag aaaaatgaag aactcatcct
     3661 tccaatgaac aacagccttt cgttaacatt ggatgcattt tatacagaga cagaagtcat
     3721 cttttctgat agctatatgg tagatgaatt ttatctagat ggcaccttgc aagacgaaaa
     3781 agcaacaaaa aaagtcagtc agtttcttga cctttttcgt aaagaagccg gcctctcact
     3841 aaaagcttca gtaatcagtc agaatttcgt tcctaccgca gctggattag cctcctctgc
     3901 cagcgggcta gctgctttag caggcgcttg caatactgct cttaagcttg gattagatga
     3961 tctctctctt tcaagatttg ctcgacgcgg gtctggttca gcttgccgaa gtattttcgg
     4021 tggtttcgtc gaatgggaaa aaggccatga cgacttaagt tcttacgcta agccagtccc
     4081 ttccgattct ttcgaagacg atttagcaat ggttttcgtt ttgatcaacg accagaaaaa
     4141 agaagtgtcc agcagaaatg ggatgcgtcg gacagtcgaa acatccagtt tttatcaagg
     4201 ctggttagat tccgttgaag gggatctata tcaattgaaa caagcaatca aaacaaaaga
     4261 tttccaactt ctcggagaaa cgatggaaag aaacggacta aaaatgcatg gaacgacttt
     4321 agctgcccag cctccattca cttactggtc tcctgacagc ttaaaagcga tggatgcggt
     4381 gcgacaattg agaaagcaag gcattccatg ctactttacg atggatgctg gccctaatgt
     4441 caaagtttta gtggaaaaca gccatttatc tgaggtacaa gaaacattta ccaaattatt
     4501 tagcaaagaa caagtaatta ctgcacatgc tggtccagga attgcgatta ttgaataaag
     4561 ggagattttt atgattgaag tatctgcacc aggcaaactc tatattgccg gagaatatgc
     4621 agttgttgaa acaggccatc cagcagttat cgctgcagtc gatcaattcg tgacagtcac
     4681 tgtagaatct gcacgaaaag tcggaagtat ccaatctgca caatatagtg ggatgcctgt
     4741 acgttggaca agacgcaacg gagaattagt tttagatatt cgggaaaatc cttttcatta
     4801 tatccttgct gctattcgct tgactgaaaa gtatgcacaa gaaaaaaaca ttcttttatc
     4861 cttttatgat ctgaaagtaa caagtgagtt agacagttca aatggccgga aatatggatt
     4921 gggttctagc ggtgccgtga ccgttgcaac ggtcaaagcc ttgaatgttt tttacgcgtt
     4981 gaatttatct cagttggaga ttttcaagat tgcagcacta gccaatttag cagttcaaga
     5041 taatggttcc tgcggcgaca tcgctgctag ctgttatggt ggctggatcg ctttctcaac
     5101 cttcgaccat ccttggctcc aagaacaaga aactcagcat tctatcagtg agttacttgc
     5161 cctggattgg ccaggtctat ccattgagcc attgattgct cctgaagatt tacgtttatt
     5221 gattggttgg acgggtagcc ctgcctctac ttctgatttg gtcgatcaag ttcaccgttc
     5281 gagagaagat aaaatggtgg cttatcagct tttcttaaaa aatagtacag aatgtgtcaa
     5341 cgaaatgatc aaagggttta aagaaaataa tgtaacgttg atccaacaga tgattcgaaa
     5401 aaaccgacaa ttactgcatg atttatctgc aatcactggg gtcgtcatcg aaacgcctgc
     5461 tttgaacaaa ttgtgtaatt tagctgaaca gtatgaagga gccgcaaaat cttctggtgc
     5521 aggtgggggc gattgcggaa tcgtaattgt tgaccagaaa tctggcattc ttcctttaat
     5581 gagtgcatgg gaaaaagcag aaatcactcc actgccgtta catgtctata gcgatcaaag
     5641 aaaggaaaac cgatgaatcg aaaagacgaa catgtttcac tagctaaagc ctttcatgat
     5701 aaacaaaaaa acgaatttga cttcgtacgg atcatccata accctttgcc gcaaatagca
     5761 gtttctgatg tcgatctaag tacacaggca gttgggttta cactaagcag cccattttat
     5821 atcaatgcga tgactggcgg aagcgaaaaa acaaaaaaaa tcaaccaaga tcttgcaatc
     5881 gtcgcaagag aagcagattt gatgattgcc actggttcag tcagcgctgc cttgaaagtc
     5941 ccttctttag ccgatactta tacgattatg cgacaagaat atcctcacgg gaaaatcatt
     6001 gccaacatcg gtgcagggac ttctgtcgaa agagccaaag aagctatccg attgtttcac
     6061 gcagatgcct tacagattca tttgaatgca cctcaagagt tggttatgcc tgagggagac
     6121 cgtgatttta ccaattggaa agtacttatt caagaaactc aaacagccat tgacgtcccc
     6181 ctcatcgtaa aagaagtcgg ttttggcatg acaagagaaa cgctcaatga tctagctgct
     6241 ttaggagttc atacagttga tatcagcggt cgaagcggaa caagcttcac ccagatcgaa
     6301 aacgcccgtc gctccaagcg ggaactgagt tatttagctg actgggggca atcgacagtc
     6361 tcttcattgc ttgaagcaaa tgaagcagac acttctatgg aaatcctagc ctccggaggt
     6421 atccgcaatg cctatgacat atttaaagcc ctttgtctcg gcgcaaatgc cgtgggtact
     6481 tcaggaaccg tactgacgca tctgatgaat cacggcgtag aagaaactat tatactgatg
     6541 aagcaatggc aagaagagct tcgtctgctt tatactatgg tcggcgcaac gaataccgcg
     6601 gccctacacc aacaatctct gatcttttcc ggaccagtga aggattggtg cgaagcaaga
     6661 gggatcgact tagtgaagta tggaagacgc acagaaaaga gcgtgggaca aaagtaaaga
     6721 acacttttgt ctcacgctct aaacacgtac aaacggcgga agtaaaagca actccttcgg
     6781 aaataagctg aaattcacaa aaatttgaaa agcaattttc gtgaattcct tcttatttct
     6841 tggagttaaa tgcttctgtc ccagcctctt ttttcgaata aatgatgttt aatcagctgt
     6901 ccttcggtat tcgttcaatc cgctgatttc acaacctctc cactaaacag tgtactaaag
     6961 ctcttttaag gttgttttcc gatataggca agtatgcctc cgtccacata caagacatgg
     7021 ccgttaacga aatcagatgc gctagaagcc aagaagacag atggtccagc caaatcgatt
     7081 ggctcgcccc agcgtgctgc tggcgtacgt ccaacgataa attgatcgaa tggatgacgt
     7141 tcaccgtttt cttgtgtttc gcgtaatgga gcagtttgcg gtgtagcaat ataacctggt
     7201 ccaattccat tacattggat attgtattga ccgtattcag aagcgatgtt tttcgtcagc
     7261 atttttaatc cgccttttgc cgcagcataa gcactgaccg tttcgcgtcc taattcactc
     7321 atcatggagc agatattgat gattttaccg ccgccttttt cgatcatatc cggaataact
     7381 gcttttgaaa cgatgaatgg ggcatttaaa tccacgtcga ttacttggcg gaagtctgcc
     7441 gcatccattt cgatcatcgg tgtccgtttg atgatccctg cattgttgac tagaatatca
     7501 actgaaccta catcttcttt gatctgttga accatcgctt gaaccgcttc ttcatcggtc
     7561 acatcgcaga cataaccttt tgcatcgatg cctgcttctt tataatgcgc tataccttca
     7621 tcaactgatt cttgattcaa gttattaaat acgatttttg ctcctgctgt agctaaagag
     7681 cgtgcaatct caaatccaat accatagaca gcaccggtga ctaatgctac ttttccatct
     7741 aaacgaaaca tatccatact aaattccatc attttctctc ccttatgctt attttaattg
     7801 atccatttgc accatatcca tgtctgtata ggtgatattt tctccgcaca ttgcccagat
     7861 gaatgagtaa ttgcttgtac ctacacctga atggatcgac cagcttggcg aaataatggc
     7921 ttgttcattg tctacaacta aatgttttgt ttcatctggt ttgcccatca tgtggaacac
     7981 acgtgtatct tcattggcat aatcaaagta gacataagct tccatacgac gttcatgtgt
     8041 atgacaaggc atcgtattcc aagcgcttcc tggttctaaa atcgtataac ccatttgtaa
     8101 ttgacagctt tcgcatacat ttggatggat gtattggtag attttacgtt cattcagtgt
     8161 caggccttca ccagtctcca ttggttttac ttggtcgata ctgattttta catttggata
     8221 tttatgatga gctggaacag aactaatata gaatttagct gggttttcag catcttgaga
     8281 agaaaataca acatgtcgtg tttcttttcc gatatagtat ccgtcttgtt ttttcatttc
     8341 ttctttttgc ccatcgatct cgatgaatcc tggtccaccg atattgatca cacctagttc
     8401 acgacgctct aagaagtaat caacacctag ttctttgtct aatgtgattt ctaattcttt
     8461 ttcagtaggt gtcactccac caaagatcat tcgatcgttg tgcgtataag tcaaactgat
     8521 tttccctggt tcaaatacct tttctactaa aaattctttt ctcaattgtt ccgttgaata
     8581 atgacggata tcttctggac tgtgtgtata acgtgtttcc atttcttgca ttttcttcta
     8641 ctccttctat cgaatgattt ttccagagcc gcatgctaaa aattgtgcga cttcttcttg
     8701 actaaattgg ttgcagtccc catggatcgt atgcttcaag gcagaagctg ccgtagcaaa
     8761 atcaatgatt tcttgcggag acatattgga taaaatccca tggagcacgc cacctgcaaa
     8821 agcatctccg ccacctactc gatccacgat tggggtgatt ctatggactt gggattccac
     8881 atattcatgg ttcatccaca atgtcccctt caattcattt tcacttgctg aatgaacggt
     8941 acgcttggtc gaataaaaca cctgaatatt cgggaacttt tcctgcattt tttgataata
     9001 ataaattaga ggttgttctt ctgcttctgg cgctttctcg atacctaaca aataaagagc
     9061 atccattttt ccagctgagc agatatctac taaaggtaaa agctgatgga ttacttcgct
     9121 ggcttcttgc tgtgtccata attttccacg atagttgata tcgaagctga tcaggcagcc
     9181 agcttttttt gcagcttcta tcacctgttt cgtcattttt tgccattttt tagacaaagc
     9241 tggggtgatt cctgaaacat gaaatatatc tattccttgg aataactcct ctagcgacca
     9301 ttccaaatga tccatttcag caaaacttga tccggcacga tcatagatca ctgaggcggc
     9361 gcgttcgcca ctaccagttt ccatataata agtacctagt cttgatccac cagataatac
     9421 ctgtttcgta tctactccat aacattgcaa gtgctttttg actgcttttc ccaatgcgtt
     9481 atcaggtact tttgtagcaa aaatcgcttc atgtccgtaa ttagctaaag aaattgctac
     9541 gtttgcttcc cctccgccat aatgggcagc gaatcgttca cttgaatcga tacgggttcc
     9601 ctgctctgtg gacaatcgca acatgatttc tccgagtgtc actacttttc ccataagcag
     9661 ctacctcttg atttctttca tttttgctgc atactgttgc gcgacttccg ttactttgtc
     9721 aaaatctcct gtagctgcgg gtgctaaaag gttcccacct actccgactg ttacgacacc
     9781 agcatcgaac cactctttca tattgtccag actcacaccg ccagttggca tgatattgac
     9841 ttgaggcatc ggcgccttga aggcagaaat gatacttggt ccataagcgc ttccaggaaa
     9901 tagtttgacg atatctaccc cgcttttcag cgctgttttg atctcggtaa tagtcataca
     9961 tcctggtaag taaggaattt gatacagatt gcacatctct gccgtttctt gatcaaagga
    10021 agggctaaca atatactctg cgccagctaa gatagccaag cgagctgtga cagcgtctaa
    10081 tactgtgcct gcgccaatca ctatttctgg ttggtctttg tagaatgaca aaagttcttt
    10141 gattacttga tctgcttgag ggactgtaaa agtcaactca ataccagtta gaccaccttt
    10201 gatgattgcg tggcaagcat tcaaagcttc ttctttgctt tttccgcgta ccaccgcaat
    10261 cactccggcg tttttcaatc gagataaaat atcaattttt ttcatcttct ccacctattt
    10321 cctatttaga aattttattt tataacttgg aaatctatac ccatattata cggcagaaaa
    10381 gaaaaattgc aaacgctttt ttcattattt ttgaattctt tgctcgattt cgctttttgt
    10441 ttgcttgagg gcactgatta tttgttcttt tgtctcatct gttaaacgat atttcggcat
    10501 acttacacta aatgcaccaa tgatttgttc gtttttcacg attgaggctc ctatacaaaa
    10561 aatatcacgt tcgatttctt catcgtcaaa tgcgatgtgg gtttctttta ccgtttggat
    10621 ttcctttttc aaccgtaatg cattggtgat cgtatattct gtgtaaggga tcaacggatg
    10681 cttttcaaga taatcagtgt actgctcttc actgaattct gctaatacgg ctttgcccat
    10741 cgcagaattg tataatggtc gggtgattcc gatttttgaa gacatgcgga tcgtttgatg
    10801 ttttggatct agtttgttca cgtacaagat ctcattgttg tccaataccc ctaagtggat
    10861 agtctcatcg atcttttgct gcagctgttc taaaaacggt aaagtcaact ctaccaaatc
    10921 gatttgttca atgtttttat tcgcgtagcg aataagcttt gcacctaaac gatagttttt
    10981 ctctgaattt ttatttacgt agccgatcat caacaaagta tctagtattt tcaagactgt
    11041 agaagaggtc attcccacac cctttgcgat cgtctgcaaa gagacatctt ggttttccgc
    11101 taaatagtct agtattttag aggctttgat caatacagtt ccataaggct ttttattttc
    11161 catataatat tctcctattt ctttataaga aaaattatag cggaaatacc atcaatttaa
    11221 aagagatatc cagatataaa ctaccatttc tctttacagg caatttaatg ttgaagatcc
    11281 gcttcgtttt tacatcaaac tttgatataa agcaatgatt tcttctactg tcgtttctct
    11341 tggatttcct ggtgtgcata catctcgcaa agcatcttct gcaattgctg gaatatctgc
    11401 ttcttttaca cctaattcag aaatggtttc tgggattcca accgctttgc tcaaccgatc
    11461 gatctcacca caagccgctt ctcttacatc ttctaaagac atttcagctg ctcctttaat
    11521 ccctagaaca agagcgatct cacggtactt ttctccagta tattctttgt tatatttcat
    11581 gacagttggc aaaagtgctg cacacgctac gccatgagga atgttgtacc atgcacttaa
    11641 cgggtgagcc atcccgtgta ccagtcctaa accgacattt gagaagccca ttcccgcaat
    11701 atactgtcct aatgccattt tttctcgccc attttgatcg ccatctacag aagcttccaa
    11761 agaatggccg atgatttcga ttgcttttaa atgcagcata tcagtcattt cccaagcgcc
    11821 ttttgtgata aacccttcaa tagcatgcgt catagcatcc atacctgttg atgcagccaa
    11881 ttttttcggc attcccatca tcatatcgct gtcgatgaac gcgacgattg ggatatcatg
    11941 aggatcaaca caaacaaatt ttcggtgatt tacttcatct gtgatgacgt agttgatcgt
    12001 tacttctgct gctgttccag aagtcgttgg tatagctaat ataggtaaac atggattttt
    12061 cgtatcagca acaccttcta aactaatgac gtctgaaaac tctggattcg tcaaaataat
    12121 cccaatggct tttgccgtat cgattggcga acctccaccg attgcgatca aacagtctgc
    12181 ctctgcctct ttaacaaaag ccactccatc ttttacattt tggatcgttg gattaggtac
    12241 gatcccgtcg tataaagcat aagcgattgc tgctttatct agaagttctg ttacttttgt
    12301 tgctataccg tgctcgatca atcctttgtc agtaatgaca gctgctttgc cgaatcctcg
    12361 ctgctgaaat tcagggacga tcgactcaat cgctcctttt ccaaaatacg atgtttcatt
    12421 taaaatcatt cgattactca ttttctattc ctcctaattt gtattatttt tcacaataaa
    12481 aacgaaagaa ccccaagcaa ccggttgccc agttgcttgt tgctacagtt caaagactgg
    12541 catcaattcc caactgactg gagaggcatc tggatttgtc tccatgatat cttccatgta
    12601 cttccaccat ttttgattga tagatgtatt tgccattttt tcccataact tttcatcttc
    12661 gatcactaag taaccaaata acaaacttgt actcggatca agatagatcg aatagtcgat
    12721 gaccccgtgt tcacgaagtg ctgtacgcat ttctggccaa agttcatcat gtcttttttt
    12781 gtattcttct tgtttttctg ggtaaacttt catgcaaaaa gcttttttca ccatgtcaga
    12841 cacctgcttt cgtatgaact tcctccaaat aacctgcttt tggagtgaca ccaaacgcat
    12901 ctgctaaatg ccacaggttt tcgtccgtga ttgtttgcaa gattggtcct tgcgctttga
    12961 cgtacgtata gacttctgct gccttttctg ctgtctcgat caaaccaaag acttcatcca
    13021 tgtcttttcc tgacccgtag attccatgtt gtggccataa aaccaatcga gtttctttca
    13081 ttttttcagc tgttgcttcc ccaatctcat ttgttcccgg aaccatccac ggaatgatgg
    13141 aaattccttc tggaaaaaca actaagcatt ccgtacacat ttgccatagc gtacgactaa
    13201 aggaacgttc gtctaattca tgcgtaaaac tcatcgctaa tagatgacta gcatggcaat
    13261 gcataacgat ccgattatct gggtctactt ctaaacgggc gatatgactc atgaaatgac
    13321 ttggcaactc gcttgtagga aggcattcgt tttccagccc ccacaaaagt tccagtgttt
    13381 tgccatcttc agcaactcga acgattccaa gattctcggc aggttcgctc gctacatttt
    13441 taaaatatct tcctgaacca gttacaataa aatagcatcc tgctaaacgg ctggcatcaa
    13501 aaatcatcga gatgcggcgg atcacttttt caggatccaa gaacggtgtg atctcttctt
    13561 cttttagtaa ataagaaata ttcccgccat ttctttcatc ccatcccaag cgataaagat
    13621 tcgacgtcgt ttcgatcatt tctttcacat aaggcgcttg taaaatatct atttttttca
    13681 atatagccac actcctattt tcttaattcc aacacgtctt tttgatattc ctggacttct
    13741 tccagccaat ccaaaccaac tggaacttga tttttgtaac agaaataatt ccatacatcg
    13801 gcatacggga aatctttcaa ttcttccgta taagccattc ttgaagtaaa gtcaaaagcc
    13861 agctccattt ctttcaatcg ctcaactggt tccagcatag ctttcagcag tgctttttgt
    13921 gtatttctcg taccgatgac ccaagcagcg atacggttga tcgttgcatc aaagaaatcc
    13981 agaccgatat ttgttttttc caacaattcg ttacggacta attctttagc gatttcctgc
    14041 aattcatcat ccatcaaaac cacatggtct gaatcccaac gcactggacg ggaaacatgc
    14101 aacatgattc ctttgctgaa taaagctaat gaagataatt tattggaaat cacttctgtt
    14161 ggatgaaaat gtccagcatc tagacaaaca agtttgtcac gagtcaaccc gtaacccata
    14221 taaaattcat gggaaccgac tgtataagct tcagcgccta aaccaaatag tttgctttct
    14281 actgcatctt gtacataccg ttcatctaac tcttctgtaa aaatttcatc gagtgattcc
    14341 attaaacgtt cccgtggggt aaaacgatca atcggattat ctttcatccc atcaggtacc
    14401 caaaagttat tgatacttgt ttgcccagtt tctttcccaa agtactccgc gattttgcgg
    14461 cttcttttcc cgtgttcgat ccagtattca cgaacttctt tatctggatg agccaatgta
    14521 aagccgtctt tcatcattgg atgcgaaaag aaagtcggat tgaagtcaag accgatttct
    14581 tctttttttg cccactctac ccatttttca aaatgtttcg gctcaatttc atttagatcg
    14641 acagattctt ctgtatccaa atagatagca tgaaggttca atttgtgttt gcccggtatc
    14701 aacgaataag ccttctccag atcttgtcta agctcttcag gtgttcgtgc ggctcctgga
    14761 aaattccctg tcgccatgat tccaccggtc aattcgccat ccggtgtcaa gaaacctttg
    14821 acatcatctc cttgccagca atgcatagaa attttgatgt cctgtatctt ttctagtaca
    14881 gcatctgtat ctacaccgat agttgcatat ttttcttttg cttgttcgta atttctttca
    14941 atcgtgttca tacgattact cctttgattt tattcacgta ccattccatc gtgttttgct
    15001 tattttcatc tgggtaaaaa gtttcacatg gaaacgactg tttgattaca tttcttgctt
    15061 gttctatatt cgaaaactga cctgtactga gcatttgcat ggcaacattc ccgattgctg
    15121 tggcttcact aggtcctgct tctacaatga ttccggcata atctgctgtc aattgattca
    15181 gtagacgatt attcgatccg ccccctacga tgtgcagctt ttccaatttc gttccagtta
    15241 agtgttctac tttgatcagc tcttgtgcgt aacaaagagc aagattatca tacacacaac
    15301 gagcgatagc tcccgatgag acagggactg gctgctctgt ttcaaaacag tattgctgaa
    15361 tctcttctat catatttggg ggattcaaaa atcgagggtc attgatttcc atcacttgct
    15421 gcagcggttt ttcttttgca gcaagctctg ccaattccgc ataactgtac tcgtactctt
    15481 gcattcgggc aacttcctgg atcaaccaca tccccatgat gtttttcaaa aaacgcaccg
    15541 tgttatgggc accccattca ttcgtataat tttcagaaaa agcattgcga gaaacattgg
    15601 cgatctttgt ttcaatccct aaaagcgacc atgtcccact gctgatataa ccccaacgtt
    15661 ctccttgacc tggcgttcct aatacagctg acgccgtatc atgacttgct actgtgataa
    15721 aggtcacatc tggcaaatca tattttgaaa attgttcttt ttgcagatct cctagtatcg
    15781 ttcccggctc tgtcaatggt ggaaataatt ccttcgagac accgattttt tcaagaagtt
    15841 ctatttccca ttcttttgtc cctgcattca gcagctgcat agtagatgca ttagttttct
    15901 ccgtcaccat gttaccagta aagacatacc ctaaataatc aggtatcagt aacaatttat
    15961 gtgcttttgc caaattttct ttttcttcag caaacaattg gaacaaggta ttgaaaggct
    16021 ggatctgaat ccctgtctgc tcatacaact tatctagaga atagatttca gaaaactgtt
    16081 ctactgctcc attggtacgc ttgtcccgat aagcaatcgg atcatttatc cgatcccctt
    16141 gttcatcaat cagacagtaa tcgactgccc atgtatcgat ccccgcaaaa aggcgatcaa
    16201 tccctgtctg ctttaatttt tcaaatccaa tcaaaatctc tttgataaga taatcgatct
    16261 tccagcgatc gtgaccgtct ttgttccgaa agccgttttt gaaccggtgt acttcttcca
    16321 agatcaaaga accttttgca tccctcgtac ttttcattag tcgtccgctt gatgcaccga
    16381 tatcgatggc aacaaatgtt ggattcattt ctccacctct tttactttat tgttgattag
    16441 cactttatta ataaagcgtt atcatttatt aacaatgcta tcataataca gaatcttata
    16501 ttttgcttca cactattttg gtatataatt gcattatctt gacaagttgg gagtgtttac
    16561 atggattact gggaaaaagc caaccactca tggtcggaag actcaaaaag agtgatcttg
    16621 acgcctacac aaagaagcag gaatttattt ttttatatcc aagaaatcgg ttacttcaaa
    16681 gcaccaatcc cttactatac tgaacgagca catttacctt cttacttgat aaagtttact
    16741 ttgtctggca aaggttcgct tacatataat gataatcagc aacagctaaa agctggagac
    16801 ttatttttta ttgactgcca agaatatcag cgttatcaaa cgatcagcga agaaccatgg
    16861 gaaatggatt ggatccattt gaatggtcag aacgtccaat cattttatca ggagttcaca
    16921 aaagacggcc ataacacctt ccattcaaca ggggatccat cagaaaacaa gatccaccat
    16981 ttgatcacag aattgatcca catgcaacaa ggcacgaatg cccgtaccga tttccagtcc
    17041 tctgtagcta tccacgagtt gctgaatgaa ctgattttgc aaaagtatca gctagatttc
    17101 gaagaagagg atattcccgc ctacgtttac aaactgaagc aatacttaga cgaacatttc
    17161 aaagaaacga ttacacttga tcaattagaa caacaattct tattgaataa atatcagctg
    17221 agcaaagatt tttccaaatt tatcggttct ccaccaatcg attatttgat cagcaaaaaa
    17281 ctttcttacg ctaaagacct tcttcggtat acagaattta cggttcgaat gatttccgaa
    17341 gaaataggga ttgagaattt tgcttacttt agccgcctgt tcaaagcaaa aacaggacta
    17401 tcgccgagag actttcgtaa attcagctga ttcatataat atgtacgtca ttttttcaaa
    17461 atattttgaa atatatagat aaaaataaaa taaccgcagt ttctgcttct atgtaaacaa
    17521 cagcagctac tgcggttatt ttttagtgat cattctcatt gttcatcttc aaaatgttca
    17581 taatgaacca actgtttctg tgtatcacgt ttcaaaaatt ctttaggcgt tatgccgaac
    17641 tctctcttga atgctttcag aaaatgcgga taagaagaaa aaccactttt actatataca
    17701 gcactagagc tgcggtattc tcgcaacaag tgcttggcat agatcagctt tttcttcatt
    17761 acatactgat gaaacgtaaa tccagtgtac tttttaaatt ctcgtgtgat atggtatttg
    17821 ctgacaaaaa actgcttttc catttcctct aaagaaagcg gatgagataa attttttgag
    17881 atatattgta acatttgttc cacacgctca ttaggaacta cagcattctg ttcttgcgca
    17941 ctctcttctt tttgtacaac ttgattgaga aaaatcaagt attctaccag agcttgttca
    18001 tattttatgt cttcaccgta aattttttta tcaggaggat ggtcgataaa tgataatttt
    18061 tgcttcaata cttcctgttc tatttgcaat acacgactcc tcttctctcc cattggttga
    18121 aagcaagccg atagattaga ccatggcgtg gaacgacttt ctagaaaaga aggggtgaca
    18181 aagatataga cacgctcgaa tacatctgaa gattggcgga cgatacgatg caaatcattg
    18241 gaatggatga gcagcacact tcctgctttg atcgtaaatt gtcgtccgtt caaataaaaa
    18301 gtcgcttctc cctttaatgt agcatggatc tcatagaaat catgatgatg atagatcgtt
    18361 ttattttggc tgacgacatc tttgacatga tagatttcat actgatcaga aaccatcgta
    18421 ttgacttgtt caccgctgat tttcttttgg agcatgtgcc gcacctcctt ttgttcactt
    18481 atgcacaatt ttattatacc acgttttttg taatcaaaaa gagctgcttt tatatactct
    18541 tataaaaaag aagagacgtg gcatcttcta gccccgcccc ctccattcta aatattagtt
    18601 aaccaacgtc ttctttacat tattcaagaa gacttcttcc ataacgaatc ccatcatctt
    18661 ttgtttcttc aagaaccaca tacaggtacg gacgattctt catgatgatt tctttgattt
    18721 ttgtgtactc gatcacaccg tctcccaaat ttaccggcac gattttttcc tgttcgacac
    18781 gaaaatcttt caaatgaacc gcacatatct tttcaccaaa acgttcaaaa gcttcttcta
    18841 ccaattggac ttgttcttga taatcactac ttgtgatcaa attggtcgga tctaaaatga
    18901 ttcctagata gtccgaatct actgcttgga tcagctgctc tacccttgct aaagaataca
    18961 ccggatgatt caaacctggt tctatcccca ccatcatttg gtatttttct ccagctttta
    19021 ccaagcgacg gataacggac acagcttcag caaatgcttc atctgtgaaa ttttcttccg
    19081 tatattggat ttccggcaaa acacatccag tttccgaagc aaccatcgac gcaccaaagg
    19141 aagaagcata gcgaagatac tgctcgaact ttgtcagcaa ctcttgtcgt atcgttaaat
    19201 ctggatgaat catattgata tagcaactta aaattcctac ggtcacttct tgcttttcta
    19261 aaactcgttt gacataattt cccatcccag aattgatctc atttgcgcca gaaggtattt
    19321 caggaaacga aagacctaag gcgagctgca gtgtatgaat cccttgttct tttgtttttt
    19381 ctgcaagatc ttctatcgtt tggacttcgg aaagatcatg tcctctaatt gtaatgttca
    19441 acataactat tctcctaact cagcatattg ggtagccaca tgacgatttg cgggaagtaa
    19501 gtaatcaaaa acaagacgac taagataacc ccataaaaag gaagaagcgg tttcagcatt
    19561 gcctctgctt ttacgcctcc tacacttgca ccgacatata gtcctgtacc tactggcggc
    19621 gtgatggagc ctacacacag attcatgatt gaaaacaacc cgtaatgtac aggatcaacc
    19681 cctacacttg tgacgattgg taaaaatatt ggtgtaaaaa tcaagatagc aggcgccaca
    19741 tccataaaca tacccaccag taataacaca agattgacta ataacagaat aataaattta
    19801 ttatccgtta cgcccataat caacgaacta attgcctgag gaataccggt aaacgccatg
    19861 gcgaaagaca tcatggaaga agtagccaat aagaacatga tcgtccctga cattgctact
    19921 gattgaaaca acatattagg tatatctttt agttttaccg ttttatagta aaacatagca
    19981 atcaacaggg agtaaatgac agctatcgct gaagcttcta ctgctgtaaa tatccccgtc
    20041 aagataccac cgataatgat gacaatcaat agaaggctag gaatcgcctc ttttattatt
    20101 tttccagcat gagccatctg tcctttttcg acaacagggt atttattctt tttagcaacg
    20161 atgaatgcta ctagcatgat tcctagcgcc cacaaagcgc ctacgagata acctcccata
    20221 aacaaagcag agatcgaagc accaccagca acaagtgaat acatgataaa agcagtactt
    20281 ggaggaatga ccatacctgt cggagctgac gcgatattga ccgctgtcgc aaacttccgg
    20341 tcatatcctt cttccacttg ctgagggatc aacactccgc caatcgcggt agaagcggca
    20401 atggccgagc tagagatgga accaaataaa gcattcccta acacattcgt atgagccaaa
    20461 gcccccggca cgcgcccgac gaacaacatc gcaaaatcca ctagtttctt agctatccct
    20521 ccattattca tgataatgcc cgagagaacg aaaaacggaa tagcgatcag cgaaaaacta
    20581 ttgatacttc ccaccatttt ttgagctgaa ctaaaagcag aaacatcaaa cggtataact
    20641 aacaataaag tcatcatcga tgagaatgca atacttatag caatcggcat ccctaataca
    20701 agcaacacaa caaatacaaa aaataacact aatccggctt ctattgccat tttattcctc
    20761 catttttata ttttttcttg aattgctggc ttgttgctta atgtatcgat tagattgatc
    20821 aggctataga taatgatgag tacccccgat acaggtactg acagataaac atatcccata
    20881 ggaatactta aagaaggcga gatctgcccc attgtcaatg tgacagcatt ccatccgcca
    20941 tacaccatga tcatcgcagc aaataccaga aataaacttt gaacaacaac ttctaaaatt
    21001 ttactttttt tgccagttaa tttttcactt aaaaccgtta cggctaaatg tgctttttgt
    21061 cccacaacat acgcggaaga caacatggca aaccagacaa gaccgaatcg aacaagctct
    21121 tccgtgaccg tatttggatt tcctaaaacc gttctggaaa atacttgcca taaaacaaca
    21181 gcgaccatcc caacaagcaa aacagctccc aggatctcta ataccttgtt taaaatcatt
    21241 ttcatcacag ctacgctcct tgctcttgga tcttttgata aaggtctttg taggtaggat
    21301 cgtttttgaa tatatcatga agtggggcaa ctgcctctcg aaacggtgta ttatctacat
    21361 cattgaattg gactccatgt tcttcttgtg ctaaagcttt ttcttcttca attgcttttg
    21421 caaaagcttc aatttcaaaa accgttgatt ctttcgctgc ttcttcaatg gctttttcct
    21481 gctcatcagt tagctgttct ttgatggcat cattcatgat gatgatatct ggcacacgtg
    21541 tatgctcatc ataggaatag tatttagcca caccaccatg tccagctgta tacaagacaa
    21601 attcattgtt ttctgatccg ttgatcaaat tggattgaag agacgtgtac acttcatcac
    21661 ttcccatagg tacgggcgaa ccgcctaaaa gctctaccat tttgatagcg gtttcgcttt
    21721 gcatcacacg gatcttcttt cccttcaaat cttccggcgt atggatcgga ccgtctacca
    21781 tataaaagct gcgctgacca gaatcataat aggtcaatcc ggtaaatcct aaatttttgg
    21841 tcgattggta gattggctcc attatttctt cattatccat caccttaaag aaatgttctt
    21901 catcattgaa tagataagga actgaaaaaa tcgaataatc tttagagaaa ctttccaacg
    21961 ctgaggcact tacttttgtg aaatctactg ctcctgactg tgtcaattcg atcagttcac
    22021 gttctccacc cagttgtcca tctgggaaat actggatctg tacggaacca tctgtttttt
    22081 cttttactaa acgcccaaat tcattcattg catcaattac tggctggctg ttgcttgcat
    22141 aagcaaagcg caaggtaact atctcattta catctgcatc tgcgacagtt gccacactag
    22201 aattatttcc gcagccgctt agacctagca gacctaggct aagcgaactt gctgcaaaca
    22261 gcagtgatgt ttttttcata tgggtttcct ttcttttaac aataagagac gagcaattct
    22321 gtcaaacaaa gcaccgttaa cgactgtcca taaggcattg ctgtgattcc gatattccga
    22381 taaaaatcta aactgtcccc cattcctgtc ccgattgaaa cgttttgaac ttctcctttt
    22441 tcatcgattt gttcaagcaa tccttggata gcacgataag cgacttcttt atattcttgt
    22501 ggtaaataac gtttatggac cgctttcaaa ataccgtaag caaatcctgc agttgcagaa
    22561 gattctacgt aagaagaagg atcatccaac aacgtatgcc ataaaccgct ttcagactga
    22621 taagttttta atgcacgcac ttgtgcttca agtgtttcga tcaataattt gcgcaatgca
    22681 tcttctttcg ataattctaa gatttcaatg atctctggaa tagcaatcgt caaccagcag
    22741 tttccacgag cccaaaatgc ttcggcatag ttatgatttc cttcaaacgt ccagccgtga
    22801 taccacaatc ctgttcgttt atccatcaag tatttgatat ggatcataaa ctggtaacga
    22861 gcttcttcta aatattctgg gcgattcaac agtttcccga tttttgccaa aggaagcact
    22921 gtcatcatca atgtatcgtc ccacaactga ttcttatttt ccggtccata tgtggcatgc
    22981 tgtaacccgt cttcatttgt ccgaggcatg tcattcatga cccattctgc ccattgttct
    23041 aaataaggca aatagcgtga atctttcgtg tcttcataca agtaagccat agtcaatagc
    23101 ggtgccattg tattgacgtt tttgggcgga gcgccttctt ccatacgatc ctcaaaccat
    23161 tcattgacca cttgataagc gcgaggattt tttgtcatct ggtaattttt ataaatacca
    23221 tatagaccga caccttgtgg ccaattccac actgtccagc ttttgtcatc tactttcagt
    23281 ccatcaaagt ccaacaaaaa ttcaccatta tcgtctttga tcgttgtcag gttttcaacg
    23341 agcaggtcaa ttttttcttt cactaattct ttaggtacaa aaatctcttc tttaataatc
    23401 atctttacgc cactttttta aacgctttca ttttatatcc ttaatatagc agtaataccg
    23461 tccactataa atatcgcttt ttgaacaaaa actgtctaaa attgacctaa atgttaaata
    23521 acaaaagtaa ctttcagtta cttggaaatt aaaaaaagaa cttggagaaa caacgtttt
//
LOCUS       DAFBSV010000042        23365 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.043, whole genome shotgun sequence.
ACCESSION   DAFBSV010000042 DAFBSV010000000
VERSION     DAFBSV010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23365
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.043"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(110..181)
                     /locus_tag="LLB18_001526"
     tRNA            complement(110..181)
                     /locus_tag="LLB18_001526"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(146..148),aa:Arg,seq:ccg)
     gene            241..1575
                     /gene="rpoN"
                     /locus_tag="LLB18_001527"
     CDS             241..1575
                     /gene="rpoN"
                     /locus_tag="LLB18_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBK5244533.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            1724..2815
                     /locus_tag="LLB18_001528"
     CDS             1724..2815
                     /locus_tag="LLB18_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HBK5244534.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            2856..3857
                     /gene="gap"
                     /locus_tag="LLB18_001529"
     CDS             2856..3857
                     /gene="gap"
                     /locus_tag="LLB18_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBK5244535.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            3967..5157
                     /locus_tag="LLB18_001530"
     CDS             3967..5157
                     /locus_tag="LLB18_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBK5244536.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            5261..6016
                     /locus_tag="LLB18_001531"
     CDS             5261..6016
                     /locus_tag="LLB18_001531"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBK5244537.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            6132..7430
                     /gene="eno"
                     /locus_tag="LLB18_001532"
     CDS             6132..7430
                     /gene="eno"
                     /locus_tag="LLB18_001532"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBK5244538.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            7829..8968
                     /locus_tag="LLB18_001533"
     CDS             7829..8968
                     /locus_tag="LLB18_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HBK5244539.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(9035..9610)
                     /locus_tag="LLB18_001534"
     CDS             complement(9035..9610)
                     /locus_tag="LLB18_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBK5244540.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(9615..10589)
                     /locus_tag="LLB18_001535"
     CDS             complement(9615..10589)
                     /locus_tag="LLB18_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleosidase"
                     /protein_id="HBK5244541.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIASALKVNPNIGKHMERFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEEAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(10613..10657)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            10872..11840
                     /locus_tag="LLB18_001536"
     CDS             10872..11840
                     /locus_tag="LLB18_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK5244542.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            11937..12230
                     /locus_tag="LLB18_001537"
     CDS             11937..12230
                     /locus_tag="LLB18_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBK5244543.1"
                     /translation="MRSAAYGNQRRKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTF
                     VDPAYRGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            12348..12584
                     /gene="secG"
                     /locus_tag="LLB18_001538"
     CDS             12348..12584
                     /gene="secG"
                     /locus_tag="LLB18_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBK5244544.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            12687..13442
                     /locus_tag="LLB18_001539"
     CDS             12687..13442
                     /locus_tag="LLB18_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBK5244545.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            13445..15802
                     /gene="rnr"
                     /locus_tag="LLB18_001540"
     CDS             13445..15802
                     /gene="rnr"
                     /locus_tag="LLB18_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBK5244546.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            15824..16288
                     /gene="smpB"
                     /locus_tag="LLB18_001541"
     CDS             15824..16288
                     /gene="smpB"
                     /locus_tag="LLB18_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBK5244547.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            16590..17309
                     /gene="atpB"
                     /locus_tag="LLB18_001542"
     CDS             16590..17309
                     /gene="atpB"
                     /locus_tag="LLB18_001542"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBK5244548.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMVISLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            17362..17577
                     /gene="atpE"
                     /locus_tag="LLB18_001543"
     CDS             17362..17577
                     /gene="atpE"
                     /locus_tag="LLB18_001543"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBK5244549.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVVALILVFGV"
     gene            17668..18192
                     /gene="atpF"
                     /locus_tag="LLB18_001544"
     CDS             17668..18192
                     /gene="atpF"
                     /locus_tag="LLB18_001544"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBK5244550.1"
                     /translation="MLNQLAIAEVGNAMLGNVIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            18179..18721
                     /locus_tag="LLB18_001545"
     CDS             18179..18721
                     /locus_tag="LLB18_001545"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBK5244551.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYAYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMNYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLENMRNQLNR"
     gene            18744..20300
                     /locus_tag="LLB18_001546"
     CDS             18744..20300
                     /locus_tag="LLB18_001546"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBK5244552.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            20314..21216
                     /locus_tag="LLB18_001547"
     CDS             20314..21216
                     /locus_tag="LLB18_001547"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HBK5244553.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            21239..22645
                     /gene="atpD"
                     /locus_tag="LLB18_001548"
     CDS             21239..22645
                     /gene="atpD"
                     /locus_tag="LLB18_001548"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBK5244554.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            22659..23081
                     /locus_tag="LLB18_001549"
     CDS             22659..23081
                     /locus_tag="LLB18_001549"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HBK5244555.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         7865 a         4237 c         4989 g         6274 t
ORIGIN      
        1 atctatacag atacaacaaa aaactgtcca ccaattctct ttggcggaca gttttcactt
       61 aaaaataaag aagcaactat tcgtaaatta tgctaaaata gcagtagaac gcgtcctgag
      121 ggaatcgaac ccccgtctca agaaccggaa tcttacgtga tatccactac actaaggacg
      181 caagcactgg gataattgta actaaacaga taaaaaatta caaggggatt ggacaaaaaa
      241 atgaaatttg agcaaaattt ttcacaaaaa cagcagcaga cacagaaact agccatgacg
      301 caacagttgc aacagtccat ccaagtttta caatataaca gtgaggagct gttggcattc
      361 gttgagaatc aagcaatgga aaatccattg gtggaagttg ttgagccgga atggcagcca
      421 gattacataa aagcttcttc atcttcttat gaaggagaag agacaaatta cctaaatcag
      481 attcctgata caaaagggtc tttatttgat tcattgatcg aacaagtcca tttgaattac
      541 cgagatactt ttttgaggaa aatcgttctt tatcttgtag aatacatcga tttgaacgga
      601 tttttgacga ttagtttaga agaagccgga aaagagattg gagctacgcc tatccaaatg
      661 ctcgatgcgt tgactctgat tcagcaatta gaaccagctg gagtaggtgc acgtagtttg
      721 caagaatgtc tcatgcttca aacagaacga gatgattatg cgccggaatt agcttatatc
      781 gtgttggaag aatgttttga ggaactggtg gagcgaaaat ggaaagaaat cgcacaacgt
      841 ttttctgttg atctacatgc tgttcagcag atattcgact atttacaaac gttgagtcca
      901 agccctggcc ggattttcga ccgtagcagc gaattgtaca ttattcctga tgtccgggta
      961 ttagtggacg acgataaaaa tgtacaagtt atctcaaacc gaaaaaatca gccaaatata
     1021 cgctttcaag agagttactt caaacaaatg tcacaacaag cagataaaga aactgaaaat
     1081 tatttaaaag aacggaaaca ggaattcgaa tggttgaaga aaacgatcct ccaacgtggg
     1141 gatacaattt tgcgggttgc tcaagtcatt gtttcccggc aaaaagcttt ctttatcgac
     1201 aaggaacgtc caatcaagcc tcttacgtta aaggaagttg caactgagat agatgtgcat
     1261 gaatccacgg tcagtcgtgc agtcaacggg aaatatttgg aaacagattt cggtgtattt
     1321 gaattaaaaa aatttttcac tacacgaatt cctacgaata gtacagaaca gacagaagac
     1381 ctttcagcag atacagcgaa gaaaaagctg caggaattag tcgatcaaga agacaaaaac
     1441 aagccgttgt cggaccagaa attggttgaa ttgctgaaaa aagatgagat agcgatctca
     1501 agacgaacag tagcaaaata tcgtgattta ttaggaatcc cgagttcatc aaaaagaaaa
     1561 cgttatgata actaatcagt caaaagacta gaaaaagtat ttcacttttt ctagtctttt
     1621 tagttgaaaa acgagagcaa aactgttaga cttacagtcg tgaggttgag atttcccttt
     1681 attgatgtga aattcgaata gttaatttct ttttttatcg tatatgggtc gttttaagtc
     1741 tacattggac gtaaagtgtc caactaagga gatcgctatg ctggatgaaa taaaaatgat
     1801 tgaatctgtt gcaccagata ttatcgaagt gttgcaagaa cgctataaaa ttttacgaaa
     1861 tatctattgg atgcagccga ttgggcgtcg aagtttatcg gaaagtatgg ggatcacaga
     1921 acgagtctta cgaacagaaa cagacctttt gaaaaatctg aatttgatcg acacctcaaa
     1981 aagcggtatg acgctgacaa ctaagggcga agaagtttat caaagccttg aaaacttcat
     2041 ggatcagctt ttaggtacgc atcaaaccga acaacagttg gcagaatatt ttggtaacca
     2101 acgctgtatc gttgtttcag gaaacagcga agagcagacc aaagtggctg atgcattcgg
     2161 cgaagcgctg agcgaagcct tagaccgact acttccagaa ggcgagaata tcatcgctgt
     2221 gatgggagga actactatgg ctgtggtagc cgaacaattg tctaatctgg aaaataagaa
     2281 acggcataac ctgtttgtcc ctgcaagagg cgggattggt gaagcgataa ctgtacaggc
     2341 aaattctgtc agtgcaagaa tggctgctaa agcaaacggt aaccaccgcg cactttatgt
     2401 tccggaacaa ttaagtctgg caacttacaa ttctttactc aatgagccat ctatccaaga
     2461 agtcttaaac ttgattagtg aagcgaattg tgttattcat agtattgggc gtgcattaca
     2521 catggcagca cgtcgtaaga tgactgaaaa agaattagtc atgctgaaac aagcaaatgc
     2581 tgttgcggaa tcttttggct actttttcaa tgaaaaaggt gaagtcgttt ataaggtccc
     2641 tagaatcggc atagaattgc aagatttgga aaaagtcccg atcatcatgg caatcgcggg
     2701 cggaaaatca aaagctaaag caattcgagc ttatatgaaa aatgcaccaa aacaaacgtg
     2761 gctcatcact gatgaagctg ctgcaaatga gattttaaaa ggggtaaccc tttaaaataa
     2821 atattttttt gattttcata aggaggaaat cttaaatgac agttaaagta ggtattaatg
     2881 gttttggacg tattggacgt ctagcattcc gtcgtatcca agatgtagat ggaatcgaag
     2941 tagtagcaat caacgacttg acagatgcta aaatgttggc acacttgtta aaatacgaca
     3001 caactcaagg acgtttcaac ggaacagttg aagttcatga aggttcattc aacgtaaacg
     3061 gaaaagaagt taaagtatta gctaaccgca acccagaaga attaccatgg ggcgaactag
     3121 gcgtagatat cgttctagaa tgtactggtt tcttcacttc taaatcagca gctgaaaaac
     3181 atttaacagc tggtgctaaa cgcgttgtta tctctgctcc tggcggaaac gatgttccaa
     3241 caatcgttta taacacaaac cacgaaacat taactggtaa agaaacagtt atctcaggtg
     3301 cttcatgtac tactaactgt ttagctccta tggctaaaac attgaacgac aaatttggtg
     3361 ttgttgaagg attaatgaca actatccacg cttacacagg tgaccaaatg actctagacg
     3421 gacctcatcc taaaggtgac ttccgccgtg cacgcgctgc tgctgcaaac atcgttccta
     3481 actcaacagg tgctgctaaa gctatcggtt tagtaattcc cgaattgaac ggtaaattag
     3541 acggagctgc tcaacgtgtt cctgtaccaa caggttcatt aacagaatta gtaacagttc
     3601 ttgaaaaaga agtaactgtt gacgaaatca atgcagcaat gaaagaagct tcaaacgaat
     3661 cttacggata caacacagac gaaatcgttt cctcagatat cgttggtatg acttacggtt
     3721 cattatttga tgctacacaa actaaagtaa tgacagttgg cgacaaacaa ttagttaaaa
     3781 ctgttgcttg gtacgacaac gaaatgtcat acactgcaca attagtacgt actttagaat
     3841 acttcgctaa cttataagat agacaaacgt acaagtgtaa attatagaca tgtacattta
     3901 aaagcgggga agcaatcgcg cttcttccgc tttttttgat aataagttta ttcaggagga
     3961 aataaaatgg ctaagaaaac agtgaaagat atcgatttaa aagacaaaaa agttcttgtc
     4021 cgtgttgact tcaacgttcc tttgaaagac ggcgtgatca ctgacgacac tcgtatcaaa
     4081 gcagcattgc caacaatcaa ctacgttcta gaacaaggcg gaaaagcaat ccttttctct
     4141 caccttggac gtgtaaaaac agaagaagat aaagaaggaa aatctttagc tccagttgca
     4201 aaacgtctag gcgaattatt aggtaaagaa gtaacattcg tacctgaaac tcgcggagaa
     4261 caattagaag aagcaatccg caacatgaat gacggcgacg ttgtcgtatt cgaaaataca
     4321 cgttttgaag atattgacgg taaaaaagaa agcaaaaatg atacagaact aggtaaatac
     4381 tgggcttcat taggcgatgt atttgttaac gatgctttcg gtacagctca ccgtgcacat
     4441 gcttctaacg taggtatcgc ttcaactggt atcccaacag ttgctggatt cttgatggaa
     4501 aaagaaatca agttcatcgg tgaagcagta gaagaaccaa aacgcccaat gattgcaatc
     4561 cttggtggcg caaaagtttc tgataaaatc ggcgtaatcg aaaacttgat tcctaaagca
     4621 gataaaatct taatcggtgg cggaatgact tacacattct acgaagcaaa aggaatcaag
     4681 atcggtaact ctctagtaga agctgataaa gtagaactag caaaagaatt aatcgaaaaa
     4741 gcaggcgaca aacttgtctt gccaatcgac aatgtctgtg caccagaatt ttcaaatgat
     4801 gttgaaacac aagtaatcga aggagacatt cctgatggtt tgatggcttt agacatcggc
     4861 ccagcatcag taaaattatt tgctgataca ttacaaggtg caaaaacagt tgtttggaac
     4921 ggacctatgg gtgtatttga aatgagtaac tttgctaaag gtacaatcgg tgtttgtgaa
     4981 gcaatcgcta acttagaagg cgcaacaaca atcatcggtg gcggagactc agctgcagca
     5041 gcagaacaat taggattcgc tgacaaattc acacacatct caacaggtgg tggcgcaagc
     5101 ttggaattgc ttgaaggtaa agaattacca ggactagcag caatcaacga taaataaacg
     5161 accaagtttg ctcaattctg acgagtaatc gatcaaaagg tgaagggagt tttcatgact
     5221 ccctagccat ttttcaataa attaaggagt gtgttcctca atgcgtaaac ctattatcgc
     5281 aggtaactgg aaaatgaaca aaactgcatc agaagcaaaa gaatttgctg aagcagtaaa
     5341 aaacaaaatc ccttcaaatg acaaagttga ttcagtcatc ggatctcctg cattattctt
     5401 acaagaatta atgacatcag ctgaaggtac agaactaaaa atctcagcac aaaactgcta
     5461 ctgggaaaac tcaggtgcgt tcactggtga aacttcacca gcagctcttg ctgatctagg
     5521 tgttcattat gtgatcatcg gacattcaga acgtcgtgaa tatttccatg aaacagacga
     5581 agacatcaat aaaaaagcaa aagctatctt tgcaaatggt atgacaccaa tcctatgctg
     5641 cggcgaatct ttagaaacct atgaagcagg caaaactgct gaatggatcg aaggacaaat
     5701 tacagctggt ttagctgatc tttcagctga acaagtgtca aacatggtta ttgcttatga
     5761 accaatctgg gcaatcggta ctggtaaatc agctgacgca caaatcgctg acgaaatttg
     5821 tggagttgta cgtcaaacag ttgaaaaact ttatggaaaa gaagtatcag aagcagttcg
     5881 tatccaatac ggcggttctg taaaaccaga aaatattgct gaatacatgg caaaagaaaa
     5941 tgttgacggt gctttagtcg gtggcgcaag cttgcaagca gattcattct tgtcattgtt
     6001 agacgctgta aaataattgt tgaaaatttg tgaaaaatgc aagaaatgtt tgcactaatg
     6061 agcaaaatta actaaaatcg tatatgaggg aaatccctta ggaaaaaaca aactcaaagg
     6121 agagacaaaa catgtcaatt attactgatg tttacgctcg cgagatctta gactcacgtg
     6181 gtaacccaac aatcgaagta gaagtataca cagaaagcgg agcttttggc cgcggaatgg
     6241 ttccttcagg tgcttcaact ggtgaatacg aagcagttga attacgtgac ggagacaaag
     6301 ctcgttatgg cggtaaaggt gtaactaaag ctgtcgacaa cgtaaacaac atcattgctg
     6361 aagcaatcat tggctacgat gttcgtgacc aaatggctat cgacaaagct atgatcgctt
     6421 tagacggaac tcctaacaaa ggtaaattag gtgcgaacgc tattttaggt gtttctatcg
     6481 ctgttgcacg tgcagctgct gactacctag aagtaccttt ataccactac ctaggcggat
     6541 tcaacacaaa agtattgcca acaccaatga tgaacatcat caacggcgga tcacatgctg
     6601 ataactcaat cgacttccaa gaattcatga tcatgcctgt tggcgctcca acattcaaag
     6661 aagctctacg tatgggtgct gaagtattcc acgcattagc ttcaatcttg aaagctcgcg
     6721 gattagcaac ttctgttggt gacgaaggtg gatttgctcc aaaccttggt tcaaacgaag
     6781 aaggttttga agtaatcatc gaagcaatcg aaaaagctgg ctatgtacct ggtaaagacg
     6841 ttgttcttgc tatggatgct gcttcttcag aattctacga caaagaaaaa ggtgtttacg
     6901 tactagctga ctcaggcgaa ggcgaaaaaa caactgacga aatgatcaaa ttctacgaag
     6961 aattagtttc taaatatcca atcatctcaa tcgaagatgg attagacgaa aacgactggg
     7021 acggattcaa gaaattaact gacgtattag gcgacaaagt tcaattagtt ggtgacgact
     7081 tgttcgtaac aaacactcaa aaattatctg aaggtatcga aaaaggaatt gctaactcaa
     7141 tccttatcaa agtgaaccaa atcggtacat taacagaaac tttcgaagct atcgaaatgg
     7201 ctaaagaagc tggctacaca gcagttgtat ctcaccgttc tggtgaaaca gaagattcaa
     7261 caatctctga tatcgctgtt gcaacaaacg ctggccaaat caaaactggt tctctatcac
     7321 gtactgaccg tattgctaaa tacaaccaat tactacgtat cgaagaccaa cttggtgaag
     7381 ttgcagaata caaaggtttg aaatctttct acaacttaaa aaacaaataa ttcttttcta
     7441 atgaagatac atgatcgact attgaaagat agtcgagtat gatcacttag ttaagtaatc
     7501 gaactctcta cttgctgaaa tatcagcagg tagagagttt ttttgcaact agcttctgta
     7561 tatgatgttt acaaagaatg gtacaagaaa agatcatcct tgaaaaagga aagctaacaa
     7621 taactagcat catataagag cttttaagga tagaacagta gaataggaat ctatgagcaa
     7681 gtcctctcgt ataaataaaa taggagggaa gtagcagcat atttttcata aagtggctct
     7741 ctttcttcat ttttactttg gttgctccta tttgaaaatt cgagcacact caaatacaat
     7801 aaaaagaaat ggcaagggag aggattagat gaaaaaagaa gaaaaaatcg cgattttaca
     7861 agagatcatc cgaattaaat cagtgaatgg aaacgaaggt gaagtagcag cctatttgaa
     7921 taagcttttg gcaaaacatg acataacagg agagattgtt tcttacagag atggtagaga
     7981 taatttgatt gctcgttacc aaaagggcca atcaggaaaa gtgttaggcc tatctgggca
     8041 tatggatgtc gtggcggctg gtgatgaatc gtcttggacc tatgcaccct ttgcagcaga
     8101 aatccatggg aaccgtttgt acggacgtgg tgctacagat atgaagagtg gcttggcagc
     8161 aatggtgatt gccatgatcg aactgaaaga gtcaggaaaa ccatttaacg gaacagtcaa
     8221 attattagcc actgtcggag aagaagtggg tgaactaggt ggggaacagc tcacgaaagc
     8281 aggctatgta gatgacttag atgccttgat catcggagag ccaaccaatt acagtttgat
     8341 gtatacgcac atgggatcaa tcaactatac agtcacctcg cacggaaaag aagcgcatag
     8401 ctctatgcca gaccaaggtt ataatgcaat caatcaccta aatgaattca ttacgaaagc
     8461 aaatgctgaa atgaatcacc tcgctgaaac aatcgagaat cctgtcctag gaaaaacaat
     8521 ccataatgtt acattgatca gtggcgggaa tcaagtcaac agcatcccaa gccatgcgca
     8581 gctccaaggg aacattcgat cgattccaga atacccaaat gataaaatca ttgcattgct
     8641 gcaatcaatc gtcaatgaat tgaatcaaga gacagactat catttggaat tgatgatcga
     8701 ttacaacaaa atacctgtca aagctgatcc agattctcct ttgattcatt gcattcagca
     8761 acaattcagc cagccattac ctttagttgg agcggcagca acaacggatg cagccgaatt
     8821 tacgaaagct aaccattcct tcgactttgt cgtctttggg cctggtgtcg ttactttgcc
     8881 tcatcaagta gatgagtatg ttgaaatcga taattatttg gatatgatcg aaaaatatca
     8941 aggaattatt ttatcctact tagcgtaaga tttttttaat aaatgaaaaa acagagccag
     9001 attagcatta ttttgctaat ccagctctgt ttattcagcc tatttttctt tttgaatata
     9061 tcaagcgttg tggcaacata gtgatgacta atgaaacaac gacgatagac aacaaacgat
     9121 caaggtagtc tgtacctgcc tgtaccaaga tcacacttgt tgtctgactt aaacctaacc
     9181 catgtaatag ctgaacgatc atactggatc ctgaggaggt gatcccgcca aataactgaa
     9241 cggtaatgat cgaagaaacg atcgttccag gtaccgacaa aatcaaagcg agtaataaca
     9301 gtttcaagct gtttttatct ttgccgagat atcttggcaa aatcaatcca gcaagcaagc
     9361 ctgtgagaat ttggattggc gaataataca gagaaaaaat atctgtagtc actccactta
     9421 aaataccgct ggacaatcct gtcagcattc caggtacagg cccaagcaat gcaccagcaa
     9481 aaatcgttcc gatagaatcg agatagattg gcaaacgaag ccataaagca atcgttcctc
     9541 caatataatt gatcccaata cacaaagcca tcactgtaag tacgcgagtt gccattttgt
     9601 ttttattcat tttgttagcc catctttaac ctttccaaat ctttcataat cgtttcttct
     9661 tgtgcattta aaagaacggt taaaaacttt cggaaaaaaa gacgagtatc tacttttgtc
     9721 ataattttac tgttagcagg tttctgccaa aattcataac gatcaaccaa tgtttgtcca
     9781 cgacttattc cttgagtttc cacagcagtg aagcttttga aaccttcaca gatggcctcc
     9841 tcgataaaat aagcaacagc taacggatca ttgatgacac atcctaaaat tctttcttgt
     9901 ttccagtgga agtcaaaata aaaacgagtg atcgctttta gatactctcc ctcttcagga
     9961 ttcatttgac agcagtattc gaggatagtc ggtgtcaaga cgatttctct tgtcacatct
    10021 aacccaacca tttctatcgt ttgtttgaga ttctcgaata cataagaagc tgcttcagga
    10081 tcacaccagt aattgtattc agcaactggc gaacagttac catggctttt gtaagttcca
    10141 cccatcgaga caaaacgttc catatgtttc ccaatatttg ggttgacttt caaagcagaa
    10201 gcgatattgg tcaaaggacc caaagcaatg actgatgtat ttgtcttttc tttgaaataa
    10261 tcagccaaaa aatcaacggc atggagaggt tctgcctgtt ttctcaagat catcgggaaa
    10321 tttgtttccc ctaaaccatc cataccatga gtgtcttgtg cactgatgaa aggttgcttc
    10381 aaaggttttt ccattccttg ataaacagga atgtctaaac gatcacagcg ttccaggcat
    10441 ttcagcacat tctgcgtacc tatatctgca gggacattcc cacaaactac ggtaatagca
    10501 actacttcga tatcagggga tttgacagct aatgataaag ctaaagtgtc gtcgatccct
    10561 ggatcgcaat caataattac ttttcgcatt atttccaatc tcctttcttt agagatactt
    10621 agttttttat tctgggaagt ttccgaacca gtccaagacg agcgtcttga ttataatgca
    10681 cgaaattagt atactggctt ttattgcgaa tgtaaatgct ctcttacaag taaatctatt
    10741 gaggagaact ttaagtaaat gatacaatga aaaagaaatg gaatttacgt gtgccgaaaa
    10801 taaagaatcc tatggatcgg tacattggat aatagataga ttatagtttg gcagaaagcg
    10861 gcgggtgtac aatggttatt ttttatttca ttcttattct gataattata gggatcagtt
    10921 accattttct ttcttatttt tatgcaaaga aattagtaag agcgggagta cagagaggat
    10981 atgactggta tgaagacact ggtcatcgtt tgatggaccc tgctgcagtc acgtcagtag
    11041 aaaaaaaacg acaaaaatta gaagaagagt gtgaaagctt ttgggagcag ggaacaccca
    11101 aaacaatcaa aagttatgac gggttgaaac tagctggtca gatgttcatc catccaaata
    11161 agcagaataa atgggtcatt tgcgtacatg attaccgaag cacagggaaa agagacatgt
    11221 ctcatatagg taaaagatat gcagagaaag gattcaacgt tcttgtacct gatttacgtg
    11281 cgcacggaga aagtgaagga gaaatcatcg gaatgggatg gctagatcgg ctagatttaa
    11341 ttgcctggat ccaactcatc ttagatgaac agccgaatgc gtccattatt ttacacggcg
    11401 gatcaatggg agcttctacg atcatgatgg caagtggtga aaaacttcca tcagcggtca
    11461 aaggatttat tttagacagc ggatatgttt ctgtttatgc agaattccga tatatgttaa
    11521 gtaaaatcac tgtctttcct aaaaaaatgg tcatgagata tgcgaatcat tatgcccaga
    11581 aatacgccgg ttactcctta aagcaagcat cagctacgag acagcttggc agcaatcatc
    11641 tgcctttatt agtcatccat ggtgaaagag atcattttgt ccctacagaa gcagcgtaca
    11701 cgattcaaaa tgctacggca ggggataaag cactgctgct tgttccggaa gcagaacact
    11761 tggaagcatc gatgaaagat ccgaaaacct attggacagt gattttttca tttattgaac
    11821 aaagaataac gatgaattaa ttttctcttc ttttttgtaa gtaattcgag gataaataat
    11881 tgtttataga tcaggagact gctaaaataa ggtaggaata aaaaaatatc agttatttga
    11941 ggagtgcggc atatggaaat caaagaagaa aaaatcgtct tgctttattc aatgatgaac
    12001 aacaagagat cggagaaatg acatggtcag atgcgggccc agacatcatg atcattgacc
    12061 atacatttgt agatccagca tatcgtggtc aaaagttagc tgaaaagcta gtgtatactg
    12121 gagtagaatt agcaagacga gacgggaaaa agatcattcc tttatgccct tatgcaaaaa
    12181 aagagtttga aaagaaacca gaatatcaag acgtcttacg tcagtcataa gaataacagc
    12241 tgaaagtttt gaactttcag ctgttattcc atttatatag agttgtcacg gacttttatc
    12301 tatgataaag ttaaagagac gatatctttt gggaaggagg ctgcgatatg tataatttaa
    12361 ttttgggaat cgtgatcgtt ttatcgattg ttatggtcat tgcgattatg atgcagccaa
    12421 gcaagcaaaa tagtgcagcg agtgcattta ccggcggtgc ggatcaacta ttcggcaaac
    12481 aaaaagctcg cggctttgaa gctgtcatgc agcgatcaac tgcagttatg ggagctatct
    12541 ggatgatctt attatttgtc ctagcatatt tatcttcgaa gtagttgaat aagcctctcg
    12601 caaaacggcg ggcggctttt tttattgcaa agagaacgct taagaagaag ttatgaaaga
    12661 aactatggta aaatgaggcg aaagaggtga gacgagtgag acaattacca aaaccccttt
    12721 atgcaaaaca tggaaagcga gcggttttgc tgcttcacgc ttactcagga agtccaaacg
    12781 atgttcgaat gctcgcacga tttttggaaa aagcagatta tacagtttat gcgccgcttt
    12841 ttaaaggaca cggaacaatg gagccatatg atatcttgca agaaaaagca gaaagctggt
    12901 gggcagacac taaaaaagcc atccattttt tacagtctga gcagttttct gatattgccg
    12961 tattaggatt atcaatgggc ggcatctttg ctgtacgagc actagaagaa gaatcagtga
    13021 ttggcggcgg ttttttctgt tcgcctttgt ctcctgtaaa aacaaacgtg cctgaaaact
    13081 ttgaaaaata cgtacgtcaa gtgctgaaga cagcaggtaa atcagagaaa gaaatcaatg
    13141 aaaaagcagt tgcttaccgc tcgttagctg aacaacaatt aatggatata caagatcagg
    13201 cagcaatcgt agaaagtagg ttgtcagata tccaacagcc gatattttta gctcaagctg
    13261 ggaaagatga aatgatcgac cctaatggcg tatttgaaac tgcacgcaag ttgagccgtc
    13321 agcgagtgac acttcaatgg tatcctgaaa gtggtcatgt gattacagtt ggtacagcaa
    13381 gacgcgaatt agaaaaagac gtcttggaat ttttagaaaa attaccttgg aatgaggaat
    13441 aaatatgaca aaagaaacga taaaagagaa aattctcttt ttcatggaaa gcagtcgcaa
    13501 acgcagtttt tctatggaag aaatcgctga aggtttaggg ttccaaaaaa gcgatgattt
    13561 taaattacta gtacaaacga ttgctcaaat ggaaagagaa cagagtatag ttttcaataa
    13621 aaaaggaaaa gtgaaacttc ctttaaaacc aatcttgatc gaaggaacat ttcgagcaaa
    13681 tgaacgagga tttggatttg taacgattga tcccgaagaa gatgacatct atatcccaaa
    13741 agaagcgact ggttttgcaa tggatggaga caccgtagca atcgatatca tgaagcgagc
    13801 aaatacagat atggatcgcg gagcagaggg gaaagtagtc gagattcgag accgggcgac
    13861 tactcagtta gcaggggaat tcgttgctta ttcagaagaa gaaatacaag aaacagatct
    13921 ttacggcgtt gttatcccga aagatagaaa gctcaaccaa tttaaagtat atgcagcagc
    13981 agagggagtt cgtccagttg acggaagtat tgtgctgatc gaactgaccc attaccctga
    14041 aaaagggtat gcgactagtt tagaagggat aatcaagcaa gtgattggtc ataagaatga
    14101 ccctggcatg gatatcctct caattgtcgt ggctaatggt atccctacga aatttcctga
    14161 tgatgtattg tctgaagcag atgaagttcc agatcaaatc agcgaaaagg atataactgg
    14221 acgtagagat ttaagaaatc agctcattgt tacgattgat ggagaagatg caaaagatct
    14281 agatgatgca gttacggtta aaaaattaga taacggtaat tattttcttg gagtacacat
    14341 tgcagatgtt tcttactatg tgacacaagg cagtcaattg gacagagaag catatgaaag
    14401 agggacaagt gtatatttga ctgatcgagt aattccgatg atcccgcaac gtttatcgaa
    14461 tggtatctgt tcactgaatc cccatgttcc aaggctgacc atgagttgcg aaatggagat
    14521 tgatccaaat ggacaagtag tctctcatga tattttccca agtgtgatcc aaacaacaga
    14581 acggatgacc tacacagctg tcaatcaaat cttagaagat caagacgaag aaacgatgca
    14641 acgctatgct cagctcgtac ctatgttcca agaaatgggt gaattgcacc gaatccttga
    14701 aacgatgcga atcaaacgtg gcgcgatttc ttttgaggat cgcgaagcga aaatccttgt
    14761 tgatgctgaa ggacacccaa atgacatcca gctaagaagc agaggaattg gtgaacgctt
    14821 gatcgaatct ttcatgcttg cggccaatga aacggtagct gaacattata ataaattaaa
    14881 tctgccgttt atttaccgaa tacatgaaca gccaaaagaa gaaaaaatgc agcgcttctt
    14941 tgattttgct tcagctttgg gcattctggt ccgaggaacg aaaggaacga tcacaccaaa
    15001 agatttacag catgtgatcg aaggagtaga agacaaacca gaagctgcag ttatcaatac
    15061 tatgttgcta agaagcatgc aacaagcacg ctattcagaa gacaattttg ggcattatgg
    15121 cttagcggca gattactaca cacactttac atctcctatt cgacgctatc ccgatctaat
    15181 cgtccatcgt ctgatccgtt cttacagtga agataaaagt gaaagcaatc aaagttcgtg
    15241 ggctgcggaa cttcctgaaa ttgcagatca tagttctaag atggaacgtc gtgcagtaga
    15301 aacagaacgt gaagtagatt ccatgaagaa agcagaattc atgatggaca aagtgggaga
    15361 agaattcgat gggatcatca gctctgttgt gaaattcggc ctgtttatcg aactgccgaa
    15421 tacagtagag ggattgatcc atatcaatga attgaaacag gactacttcc attttgttga
    15481 aaatcattta gctcttgtag gtgaaagaac tggtctgact tttaaaatcg gacagaaagt
    15541 gcgagtaaaa gtagtcaaag ctgatccaga tgaacgagca gtagattttg aacttgtttc
    15601 cgcagaagag gttacagcgt tggaacggcc aaaaacacga aatggaaaat caggaaaacg
    15661 cgaaggaaaa caagcaggaa aacgcccaga aagaaatggc aagaagaaca aacgatatag
    15721 cgatagtaag caaacgttcg gtaagaaaaa agggaagaag ccattttaca aaggtgttaa
    15781 aaaaaagaaa aagaaaaaat aaaatgagtt ggaggaaaca gctatgccaa aaggcgaggg
    15841 aaaattaatt gcacaaaaca agaaagctcg ccatgattat tcgatcatcg acacgatgga
    15901 agcagggatg gtcttgcaag gaaccgagat caagtcgata cgaaacagcc ggatcaatct
    15961 aaaagatgga tttattcgcg tccgcaacgg agaagctttc ttgcataatg ttcatatcag
    16021 tccttatgaa caaggaaata tttttaatca tgatccgttg cgcacgagaa agttattatt
    16081 acacaaaaaa caaatcatcc ggcttgaaaa tgaattgaaa aatactggaa tcactgttgt
    16141 tcctttaaaa gtctatattc gtaacggcta tgccaaggta ttgattggtc tggcgaaagg
    16201 gaaaaaatct tatgataaac gggaagattt gaaacgaaaa gatatcgatc gacaaattga
    16261 tcgaacatta aaaaatttct ctagataatt tcattatcct ttttcgcata ttcggtgctt
    16321 ttgcttttac ttaatgataa aatttgttag catttaatct gataaaacat gattatcata
    16381 ggttttttct tagatcagga gcaccgtgta taaagaaaaa ttcgcttcgt ttttgactga
    16441 aataaaaaag tgtctaattt tcatgaaaat gttttgaatt ttctgtttca tggtggtatg
    16501 ataccgtgtg gttagaaacc gattggaaaa aaccagatac gcacatgaat tgattttatg
    16561 tgaatttcgg ggaaaagagg tgaaatggat tggatgaacg ctcgctaacg ttccacattg
    16621 gaccaatttg gtttgatggt acagtttgta taatggtgtt actgacctgt ttgattgttt
    16681 tcttcttagc ttactttttt acaagaaatc ttaagttgaa accaacaggc aaacaaaatg
    16741 cgatagaatg ggtcattgat tttagtcgag gaatcgtaac agataatctg cctagaaaag
    16801 aattgagcaa tttccatttg ttggcattta cattgttttt atttgttttt gttgcaaaca
    16861 acatcggttt agtaacaaaa atcgttttac ctaacgaaac aacactttgg aaaagcccga
    16921 cagcagaccc gtttgttact ttaactttgg catttataat gatcttactt actcacttat
    16981 ttggggtgaa aaagttaggc ttcaaaggat atttcgtaaa ttcgttcttg aaaccatata
    17041 gttttatgtt tccgatgaaa ctgattgaag aatttacaaa cttattaaca cttgctttac
    17101 gtctttatgg gaatatttat gcgggggaag ttttgctaac cttgattgca aaaatggtaa
    17161 taagcttagg ctggttctca ttgccgttag caattccatt agagatggtc tggatcgcat
    17221 tctccttgtt tatcggaagc atccaagcat ttgtcttcgt tactttatct atggtttata
    17281 tgagccataa gattgaagtg gaagaataat attcgtttta aaaacaaact actatttatc
    17341 taatttagga ggaaaacaat tatgaattat atcgcagcag caatcgcaat catgggagca
    17401 gcaatcggag ccggttatgg taacggtcaa gttatctcta aaacaatcga atcaatggct
    17461 cgccaacctg aaatgtctgg tcaattccgt acaacaatgt ttatcggggt agctctagtc
    17521 gaagctgttc ctatcttagg ggtagttgtc gccttgattc tagtttttgg tgtttaattg
    17581 aatcagtatt aaggcagaaa caatttggtt tgttactgct tttttacatg aaaactagaa
    17641 gtacttcaaa gaaaggaagg ctcgcctatg ctgaatcaat tggcaattgc agaagttggc
    17701 aatgcgatgt taggaaatgt catcgttgtc agcggctcat ttttgatact actggctctc
    17761 ttgaagcatt ttgcttgggg accaatcagc gatattttga aaaaacgtga agacaagatc
    17821 gccaatgatt tggattctgc agaacaatct cgcatcaact cagcgaaaat ggaacaagaa
    17881 cgcgaacaac aattgttagc ctctcgttct gatgcagctg atatcatcaa aaatgcgaaa
    17941 gaaagtggag aattaagccg ccaaaatatt ttgaaggatg ctcaagaaga agcagctcgt
    18001 ctaaaaagta aagcccaagc tgatatcact gtagaacgtg attcagcgct gaactctgta
    18061 aaagacgatg ttgcagaact atctcttcaa atcgcggaaa aaatcttgaa caaagaatta
    18121 tctccagaaa tgcacgaatc attaatcaat caatatatcg aaggtctagg ttcttcaaat
    18181 gaaactagat aaatatacag taggaagacg ttacgggaaa gctttatttg aactggcgat
    18241 cgattcaaat caagcagaag aaatctatca agatctcgta agcttacgtc aaatctatga
    18301 acaagtacct ggattaggta atatgttaag tgatgttcgt ctagaacctc atgaaaaacg
    18361 agaaatcatg gacaagcttg ttagtggcta tgatggaatc gttaaaaact ttttagaagt
    18421 tgtttatgcg tataaccgaa tggatgatct tttgttcatg atcgaagaat atgaacgtcg
    18481 atatgatgaa catcaaggtt tgctgttggg aagtgtcaca acagcagttc cactttcaga
    18541 cgaacaacga atacaattag aaaagaatgt tgcaaaaaca atgaactatc aatcagtcga
    18601 attaaaacaa atcgttgatt cttctattat tggtggcgcg attgttgaag ctaaccatcg
    18661 agtaatcgac ggaagcattc gcacgcaatt agaaaatatg cgtaatcaat taaatagata
    18721 gtacaaagag gtaggtgaat cgaatggcca tcaaagcaga agaaattagt gccttgatta
    18781 aagaacaaat tgaaaattat caaaacgtgc tttcagtcga agaaatcggt accgtaactt
    18841 atgtaggtga cgggatcgct cgtgcacatg gtttagaaaa cgcgatgagt ggtgagttgc
    18901 ttgaattttc aaatggctca tacggaatgg cgcaaaactt agaatcaaat gatgtaggta
    18961 tcattatcct tggcgatttc gagtccattc gtgaaggaga taaagtaaaa cgaacaggaa
    19021 agatcatgga agttccagtt ggagaggcct tgatcggacg ggtagttaat ccgctaggtc
    19081 agccaatcga cggactaggt gaaatcgtta ctgacaaagc tcgtccagta gaagcaatgg
    19141 caccaggcgt tatgcaacgt aaatctgtta acgaaccaat gcaaacaggt ctaaaagcaa
    19201 tcgacgctct tgtaccaatc ggacgtggcc aacgtgaatt agttatcggt gaccgtaaaa
    19261 cagggaaaac ttctattgcg atcgatacga tcatcaacca aaaaggtcaa gatatgatct
    19321 gtatctatgt agcaatcgga caaaaagatt ctacagttcg tacacaagtt gaaacattga
    19381 aaaaatatgg cgcaatggat tacacaatcg ttgtgaatgc cggtgcgtct caaccagcgc
    19441 cgttgcttta tatcgcacca tatgctggta ctgcaatggg tgaagagttc atgtacaacg
    19501 gtaaacatgt cttgatcatt tttgatgatc tttcaaaaca agctgttgct tatcgtgaac
    19561 tttccttgct acttcgccgt ccaccaggtc gtgaagctta tccaggggat gttttctact
    19621 tacactcacg cttattggaa cgtgcagcaa aattaagtga tgatttaggt ggcggttcaa
    19681 tgactgcctt accatttgtt gaaacacaag ctggagatat ctctgcttat atcccaacaa
    19741 acgttatttc gatcactgat ggacaaatct tcttagaaag cgacttgttc tacgcaggta
    19801 ctcgtccagc ggttgatgcc ggactatctg tatctcgtgt agggggttct gcgcaaatca
    19861 aagcaatgaa aaaagttgct gggactttac gtctagactt agcaagttac cgtgaattag
    19921 aagcatttac acaattcggt tctgacttgg atgcagcaac acaagcaaaa ctaaatcgtg
    19981 gacgccgtac agtagaaatc ttgaaacaaa aattgcatgc accgctagct gttgaaaaac
    20041 aagtagtgat tttgtatgct ttgacacatg gattcttaga tagtatccct gtagacagta
    20101 ttttagactt cgaacatgaa ttattcgaat atctggatac caatcattca gatatctttg
    20161 aaacaatccg tacaacaaaa gatcttccag aagaagaagc gttgaacagt gcgattcagg
    20221 aatataaaga catgttctta gctacaaaag gaaataattc ctctacagaa gataaattga
    20281 aatccattca aaatgcatag tgaggtgaga tgaatgggtg cttcattaaa tgaaatcaag
    20341 acacgtatcg cttcaacgaa aaaaacgagc caaatcacgc gggcaatgca gatggtgtct
    20401 gcttctaagt tgacaaaatc tgaagcttct tcacagaagt ttcaggttta tgcaacaaaa
    20461 gtaagagaaa tcgttacgca tttgactgct actcagttaa atgatattgc ctcagaaaat
    20521 cctagagggg atatcaatta caacagcatg ctgctcagcc gtcctgttaa gaaaactggt
    20581 tatatcgtca tcactgcaga tggcggttta gtcggtggat ataacagctc gatattgaaa
    20641 caaacgatgt ctattttaga agaagaccac caatcacccg atgattacgt gatgatcgca
    20701 attggcggaa ctggtgcaga cttctttaaa gcacgcggta tcaatctagc atatgagctg
    20761 cgcaatctat ctgatcagcc aagctttgat gaagtccgca aaatcgtaaa tatggcaaca
    20821 actatgtacc aaaacgaagt attcgatgaa ttatacgtat gttataacca tcatatcaat
    20881 tcgctaacta gtcagtttcg tgtagaaaaa atgctgccaa tctcagactt agatccagaa
    20941 gaagcaacta ctttcgaaca agaatatatt tttgaacctt caaaagaaga aatcttgtct
    21001 cagttattgc ctcagtatgc tgaaagtttg atctacggtg cgatcgttga cgccaaaaca
    21061 gcagaacatg ctgctggtat gacagcaatg aaaacagcaa ctgataatgc tgctaatatc
    21121 attgatgagc tgacggtttc ttataaccgt gcaagacaag gggctattac ccaagaaatt
    21181 accgaaattg ttgccggagc ttcggcacta gaatagtatt gagattggag gaaaaaagat
    21241 gagttcaggc aagattgttc aagtaatcgg tcccgttgtc gacgtggaat tttctttaga
    21301 ccaatcctta ccagatatca acaacgcatt agttgtttat aaaaatgacg aaaataaatc
    21361 aaaagttgtt cttgaagcag cgttagaatt aggggacgga gtgatccgga ccattgcgat
    21421 ggaatcaaca gatggtttac aaagaggaat ggaagtcatt gatacaggca aagcaatctc
    21481 tgttcctgta ggtaaagaaa cattaggtcg cgtattcaac gtactaggag atacgatcga
    21541 tttagaaaca cctttcccag aagatgcgga aagaagcgaa attcataaaa aagcaccagc
    21601 ctttgacgaa ttaagtacaa gtacagaaat tttggaaaca gggatcaaag ttatcgattt
    21661 gcttgcccca tatttaaaag gtgggaaagt cggactattc ggtggtgccg gtgttggtaa
    21721 aaccgtactg atccaagaac tgatccataa tatcgcccaa gaacatggtg gtatttctgt
    21781 atttactggt gtaggtgaac gtactcgtga aggtaatgac ttgtattatg aaatgaaaga
    21841 ttcaggagtt atcgaaaaaa cagccatggt gttcggacaa atgaacgaac caccaggtgc
    21901 acgtatgcgt gttgctttga ctggtttgac gattgcggaa tatttccgtg atgtagaagg
    21961 tcaagatgta ctgttgttta tcgacaacat tttccgtttc actcaagctg gatctgaagt
    22021 atcagccttg ttaggacgga tgccttctgc ggttggttat caaccaacat tggcaacaga
    22081 aatgggtcaa ttgcaagaac gtatcacatc tacgaaaaaa ggttcgatca catcgatcca
    22141 agcaatctat gtgccagccg atgactacac tgacccggcg ccggcaacag cattcgccca
    22201 tttggatgcg acaaccaact tggaacgtaa attaacagaa caagggattt atccagcggt
    22261 agatccattg gcttcttctt caagtgcttt agcacctgaa atcgtgggag aagaacatta
    22321 taaagtagca acagaagtcc aacacgtatt gcaacgatat cgtgaattac aagatatcat
    22381 tgctatctta ggtatggatg aattatccga tcaagaaaaa gtgttagttt ctcgtgcccg
    22441 cagagtccaa ttcttcttgt cacaaaactt taacgtggct gaacaattta ctggtcttcc
    22501 aggttcatat gtccctgtag aagaaacagt gaaaggattc cgcgaaatct tggaaggcaa
    22561 atacgatgat cttcctgaag aagctttccg aagtgttggc cgaatcgaag acgtcgtaga
    22621 aaaagcgaaa acactaggct actagaaagg ggtgccccat ggatcaatat ttaacagtaa
    22681 atgtggtaac tcctgccggt ttggtctatg atcaccatgc agctatcgtc gttgcacgta
    22741 cgacagctgg tgagcttggg attttgccta aacatgcacc aatcatcgtt ccattgacga
    22801 ttgatgaagt tcgtgtaaaa cgaacagatt cagataccca cgtcgattgg atcgctgtta
    22861 atggcggaat catggaagtt cgtgataatg ttgtttcaat cgttgctgat agtgcggaac
    22921 gtgaacgtga tatcgatgta tctcgtgcgg aacgtgcaaa acaacgcgca gaacgccaaa
    22981 tcgaagaagc aaaagcaaaa caagatacga acgaattgaa acgggcaact gttgcgttgc
    23041 accgagcaat caatcgtatc aaagtatcta agcactcata aaatgagatg cggatgttta
    23101 tccgtgttta agaacagtaa aaagaggtta tgacagaagt ggtcagcttc aagacataag
    23161 aaggaattta cgaaaattgc ttctcaaatt tttgtgaaat ctcagcttat ttttcgaaga
    23221 agctacttct ggaacaccgt atatcagagg ttgtaaaatc agcgttttgt cctgagtatt
    23281 agagaaacaa atggaaaata gttcctcata ttttgccgtt ttttgagcta ataccgaggg
    23341 tcagatgatt gaacaccgtt tattt
//
LOCUS       DAFBSV010000043        23225 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.044, whole genome shotgun sequence.
ACCESSION   DAFBSV010000043 DAFBSV010000000
VERSION     DAFBSV010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23225
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.044"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="LLB18_001550"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="LLB18_001550"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HBK5244556.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="LLB18_001551"
     CDS             complement(1172..1867)
                     /locus_tag="LLB18_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBK5244557.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="LLB18_001552"
     CDS             complement(1880..2596)
                     /locus_tag="LLB18_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HBK5244558.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3531
                     /locus_tag="LLB18_001553"
     CDS             2926..3531
                     /locus_tag="LLB18_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HBK5244559.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3856..4179
                     /locus_tag="LLB18_001554"
     CDS             3856..4179
                     /locus_tag="LLB18_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBK5244560.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4361..5731
                     /locus_tag="LLB18_001555"
     CDS             4361..5731
                     /locus_tag="LLB18_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBK5244561.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGNS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5861..7162)
                     /locus_tag="LLB18_001556"
     CDS             complement(5861..7162)
                     /locus_tag="LLB18_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBK5244562.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7392..9350)
                     /locus_tag="LLB18_001557"
     CDS             complement(7392..9350)
                     /locus_tag="LLB18_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HBK5244563.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9527..9793)
                     /locus_tag="LLB18_001558"
     CDS             complement(9527..9793)
                     /locus_tag="LLB18_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBK5244564.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10303..12429)
                     /gene="pnp"
                     /locus_tag="LLB18_001559"
     CDS             complement(10303..12429)
                     /gene="pnp"
                     /locus_tag="LLB18_001559"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBK5244565.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12617..12886)
                     /gene="rpsO"
                     /locus_tag="LLB18_001560"
     CDS             complement(12617..12886)
                     /gene="rpsO"
                     /locus_tag="LLB18_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBK5244566.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13137..13700
                     /locus_tag="LLB18_001561"
     CDS             13137..13700
                     /locus_tag="LLB18_001561"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBK5244567.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13953..14474)
                     /locus_tag="LLB18_001562"
     CDS             complement(13953..14474)
                     /locus_tag="LLB18_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBK5244568.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14477..15319)
                     /locus_tag="LLB18_001563"
     CDS             complement(14477..15319)
                     /locus_tag="LLB18_001563"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HBK5244569.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15312..16037)
                     /locus_tag="LLB18_001564"
     CDS             complement(15312..16037)
                     /locus_tag="LLB18_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBK5244570.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16213..16509
                     /locus_tag="LLB18_001565"
     CDS             16213..16509
                     /locus_tag="LLB18_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244571.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17077..18669
                     /locus_tag="LLB18_001566"
     CDS             17077..18669
                     /locus_tag="LLB18_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBK5244572.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18682..19422
                     /locus_tag="LLB18_001567"
     CDS             18682..19422
                     /locus_tag="LLB18_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBK5244573.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            19590..20939
                     /locus_tag="LLB18_001568"
     CDS             19590..20939
                     /locus_tag="LLB18_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK5244574.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(21067..21657)
                     /locus_tag="LLB18_001569"
     CDS             complement(21067..21657)
                     /locus_tag="LLB18_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBK5244575.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            21804..23156
                     /gene="brnQ"
                     /locus_tag="LLB18_001570"
     CDS             21804..23156
                     /gene="brnQ"
                     /locus_tag="LLB18_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBK5244576.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         6629 a         4694 c         4433 g         7469 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcgaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gcgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 agcacaggtg aaggtggcga accagaagtg atcggttcaa cagaagaata atactgaaac
     3541 aatcaggtgg tgttagaagc ggcgggtcag cagcttttaa cacgcctttt ttatttctaa
     3601 tcgtttattt tcatatgggg cttccacttt tgtaaatggc tttacaaacg aaaaatccta
     3661 atttaccaag cttttcctcg catactttta tcgtaccttt ataaaaattt atactttgaa
     3721 aaaaagtatt caattattgt tgcatttttc ctgattcttt attagaatga accctcgttg
     3781 aagtaagtat ttctagttta tcctaggatt aattataaaa ataaaacatt cgttgattcg
     3841 aaggaggtta aacagatgtt tgaaagtttt gatagcagcc gcaaccgtta cgcttcagtt
     3901 ggtgtcgtat caagtttgcc agatgaattg attgacagta tatggtttat tattgaccta
     3961 gatcttaagg gagtcattcc attagaaaat atattaacct ttgatttgat cgaaaatcgt
     4021 ggaaaagtga cgatgcattt ttctcaagca ggaagcaatg tggaaatgga tattgatttg
     4081 ccgtttgcct attcgaacca atttcctgct caagtatacg cctatgatga cggtacgaga
     4141 gaaacgatcc ttttaccaag tgagattaga caatattaag gtgatagata aacgtggatg
     4201 tcccttattt tacagaccag gccaagttgt tgattctttg actcaattct tggcttcttt
     4261 ttatggagtt tcataaatta tcattgattt ctaattggta ttctcaggat aaacgctata
     4321 tactactaac taaattttaa agatataagg agtttaaaag atgcgcgatt taacaaaagg
     4381 aagccccgct aaactgattt tgatgttcac tgttccttta ctgatcggaa atgtttttca
     4441 gcagttctac aatatgatcg atatgatcat cgtgggtcag acgctaggta aaaatgcgct
     4501 ggcagcggtt ggtgcaactg gaagcctgac atttttgatc attggctttg cccaaggttt
     4561 aacagctggt ttagccatta ttaccgcaca acgttacggt gcaaaagatt atcggggtct
     4621 gaagaaaagt tttgctgcta gtgttgtcat tagtcttgtc gtcactgtga ttttaactgt
     4681 cctaagtctc ctgtttattc gtccgatgct tcaattgatg caaactcctc ctgaaatact
     4741 tgatcaagca caaacattta tttcaattat tttattaggg atctttgcat cagtcagttt
     4801 caatttgctt tctaatgtca ttcgcgcact tggtaacagc cgcacaccac tattctttct
     4861 gatcattgcg gtcatcatca acgtcgtact tgatttgatc tttattatct attttggcat
     4921 gggtgtggaa ggtgcagcta ttgctacagt aatcgcacaa gtttcttcca gcgtactgtg
     4981 tctagtgtat atcaagaaaa aaatgccttt gttacagtta cgcaaaaaag atttcaaatt
     5041 tgaaaaagaa gagtttgctg tacacctaaa tgctgctttg ccaatggcgt ttcaatcttc
     5101 gatcatcgct gttggtgcta tcgtgttaca agcagcacta aatagtctag ggacagatgt
     5161 cgtagctgct caagccgctg ctggtcgtat cgaccaattt gcaaatcagc cgatgatgtc
     5221 atttggtatt gcaatggcaa ctttcactgc acaaaactat ggtgcgaaag aatatggccg
     5281 aatcttgcaa ggggtacgtc aaactttact gatgagtgtc ggatttagtc tcttagcagg
     5341 tgctatcgtc attttcttcg gtcatttctt tgttcaattg tttgttagcc catcagaaac
     5401 acgtgtattt gaattagcac aaacctactt caatatcaat gggtctcttt actggatctt
     5461 agcagtcctg ttcattttac gctacacact tcaagggctt ggacaaagca agatccctac
     5521 gatcgccggt atgatggaat tgcttatgcg ttcttttgca gctatcgttc ttacaggaat
     5581 gtggggatac ccaggagcag cagcagcttc tcctttagct tggatcggtt ctgttgccgt
     5641 gttgctttac tcttatatgc gttcgatgaa acaattgaaa cacatgggtg aagaggaaca
     5701 tttcacatta gaacatgcag aagcaagata gccttgatta aaagaaatcg ttgcggctaa
     5761 aaatgaaaac ttttattgaa aatatcttct tcgtttaccg aaaacaggtt ttttagataa
     5821 caaaaaggct gtgacaaaaa atgtcacagc cttttttctt ttattctatt tttctttccg
     5881 tggactctac tttgaaataa tcgatatgtg catgctggta ttctaatacc gtgaaacgga
     5941 atgatgcaat ctcaatgatt gttcctgctt ttatttcttt atatcggcta gaagcaaagc
     6001 ccgcaagtgt agtaaaattc gtttcttcaa actctggaat ctctacatga aaataacgct
     6061 ggaaatcatc taatgttagt ttgccggaga tgatataaga gccatctgac tgttccgcta
     6121 tcaatgcttc gtccaaatct gtctcatctc ggatttcccc gacgatttct tctaaaatat
     6181 cttcaatcgt cactaagccg cttgtccctc cgtattcatc ttttaagata gcaatatgct
     6241 ttcccttttt tcgcatgatc gtcaataatt tttttatagg gatcgtttca gttgttacga
     6301 tcggctcttc aatcaactgt tctactgtca gctggtcatc tttataagat tgcttgatca
     6361 aatctggcaa ggtgacataa cctaaaacat tgtcttttga ttctaagata accggatagc
     6421 gagtatgtcc ttgttcaatc gaagctttta tcgcttcttt gacggtttct gaagcttcga
     6481 atacttgcat ggacgtacgg tctacttgta tatcttttgc caaggtatca tcaaattcaa
     6541 acacgttttc caaataatga tattcttctt tggtcaactc tcctttttca taagaattca
     6601 atgcgactaa tgtcagctct tcttgagaca atgtctcttc tccttcagat acgagacgca
     6661 cacctaatag cttccctagc cctgcagctg aatgattcaa tacccaaata aaaggaaaca
     6721 ttactttata aaaataatga agtggtttaa ctacgaacaa gacgaccttc tccgtattga
     6781 cgatactata gctcttagga agcagttcgc caataaccac atcgatatac gtaactaaaa
     6841 taaatcccag cgccacagag attgtactgc taatagccga actaaaaggt agtttaccga
     6901 tcactggttc tagtaaagcc gcgacagatc cttcaccgac ccacccgatg atcaaaccgg
     6961 ttagcgtaat tcctaattga ctagctgata aatagttatc taaatggtgt gtaacatgaa
     7021 gagctagctt ggcgttcttt acattttcct tttctagttg ttccaatctt gatcgtctga
     7081 ttttcactaa agcaaattca cttgctacaa aaaatgaagt aattgcaatc atcaaaaata
     7141 aaataatgaa attgataacc atattctccc gcctttctct ttttctattg tacccttttt
     7201 ctacaaaaag attgaaaata atgcgtattc atatttagga ataaaaaagg agatgcggca
     7261 tttttcagcc acatctcctt atcacttcaa aatcattgcg ttacttgttg ctaaacagct
     7321 ttttcatgac ctctgataaa cggtgttcaa gtagctgaca ttcgacatta gttcaggtca
     7381 aagcgctact ttcacaaccg ctctttcaac catgttttcc gagtatttcc aatgataagc
     7441 ggaacagttt catgttttac ttcgctgtac tctagcccaa accatgtttc tggcgaggta
     7501 gcgatttttt tgattgccag ttttgcctgc atgatttgac gttgccattt tcctagagtt
     7561 gtcacattgg aaactacttc atcaatcagg acaaattgga aatcgccaac ttctcgccct
     7621 ggtgtcagag agtatctttg tggctgtttt ggcaaacggc cttgtttcat caaatcatgg
     7681 atgacttggc gaacatatac gttgatttcc tgttggaccc tgaaacctaa gaacagattc
     7741 acttggacaa taaaatcagt gtccatcata tctacttgat attctttcgt atatggctca
     7801 tccgtcactt ccacatgaac aaaccaatag actcgtgctc ttttaggccg tttatctaaa
     7861 atcgaataga tgaactgtcg gccaacttta tcttcagcca tatcaggaac caagaagacc
     7921 acatttgtct gatagattgg taaagaagta tcatcacgta attctctaag ctgcgggata
     7981 taatctctca aagacacatc ctcggttgac gattcgcgaa taatgttccc ttgttcccaa
     8041 ataaacatca cgactaagat gatcaaacca atcagaacgg ctacaaaacc gcctcggaag
     8101 aatttgacaa cacttgagat aaagaaaacg acttctatcg caccgaagaa aaaggtaact
     8161 aaatatgcaa gccaacgaga atgcccattt tggataagat aaaagtaaag cagtgctgtt
     8221 gtcatcaaca tcgtcacagt gatcgataga ccgtaagcag cttccatatg atgagacgtt
     8281 cggaatgtga caaccactag agaacaggcg atccataaaa tcagattgac tgctgggata
     8341 tacatttgcc cgatactgtt cccaggatac atgatcttta accgaggcag cagtttcaac
     8401 ttgattgctt ctgaaactag cgtaaacgaa cctgtaatca atgcttgcga agcaatgact
     8461 gcagcgactg ttgcaaaagc aacgccgatc acgatccaac tttgaggcat catttggaag
     8521 aatggattca ggttcttgat ttgctgtgct tcagggtttt gataaacatt caacaaccac
     8581 gcagcctgcc caaaataatt gataaccaaa caaattttga cgtaaggcca gctcagacga
     8641 atatttcgtt tgccgacatg tccaagatcg gaataaagcg cctctgcacc tgtcgtagcc
     8701 aggaaaatat ttccaagaat gaacaagcct aatttgttat ctgcactaaa aagcagctgg
     8761 atagcataat aaggattcag tgcacggata actgtccagt cttgactgaa gttcattaat
     8821 cccattacgc ctaaaaaagt aaaccaagcg aacatgattg gtccgaatgc ttttccgaca
     8881 atatctgtac caaagcgttg gaccatgaat aaaacaaaaa taataactaa agtgataatg
     8941 acgatcacgt tctggttatt accgaaccgg tcaaaaaact gcggaattcc tcgcaagcct
     9001 tcaatcgcag tcgttaccgt cacagcaggg gtcaataccc catctgctag taaggcagct
     9061 cctccgatca ttgcaggaat gatcaaatat ttcccacctt ttcggacaag tgtgtagagt
     9121 gagaaaattc caccttcacc atggttatct gcattcaatg caatcacgac atatttgatt
     9181 gttgtcagta gagtcaatgt ccaaaaaatc aatgagactg atccgataac aaaatcagga
     9241 ttgattcctg acaatccgcc attatcttca acaatcgatt tcataacgta aagcggactt
     9301 gtcccgatgt ctccgtagac gactcccatc gctacaagca ggccagccat tgatatcttt
     9361 ttggtattgt gcgttgttgc cacgtttttc cctcatttct tgttatatgg atatccttta
     9421 ggtaagcttg aatgatagat gatattctta tccatgacac ccgctttcct aaattgcttc
     9481 taattatcca agtaacacac tgaagtgtca acttatttga ataaaattat tctttctttg
     9541 gacgttctct gatacgtctt gccacaaatg aataaagagc aaggcaaaaa attgcaccca
     9601 ataatgctgg tatcaaataa aaaccgccga gttccggtcc cagtggtcct agtaaaaatt
     9661 cgccgagcca actacctaaa aaaccgataa tgatatttcc agatacgcct cccgggactt
     9721 cctttcctaa aattgcgcca gctatcaaac ctaatatacc gccgataaat aacgaccata
     9781 aaaaattcag catctccttt ccctccttta tccatatttc tcacttttat tttacgcttt
     9841 attcagaagg actccaaaaa tatgcgccaa gaaactccag aaaaaaagaa gttgtaacaa
     9901 aagtgttcag cttatttccg tagaagctgc ttctggaaca ccgtgaatca gaggttgtga
     9961 aatcagcggt ttgacctgag tattagagaa acaaacggaa aaatagttcc tcatattttg
    10021 ccgttttttg agctaatatc gagggacagc tgattgaaca tcgtttattg gagaggttgt
    10081 aaaaaagctg ttctgcatca agtaataaga acagccaagt aaaaacagct cctaatgttt
    10141 ttaacttggc tggacttatt accgcagatg caagcttttg aacaccgttt attcgaaaaa
    10201 aaaggactgt gacacggctt ttgtcacagt cccctttttt cgaataatta ttgtccccct
    10261 gtcaccttca cgatcacaag tacattattc ctatgaatta aattattttt cttcattttt
    10321 cgttgaacca tcttcgttca acattgcttt tcttgacaga tttacgcgtc cttgtttatc
    10381 gatttcagtt actttcacaa ggatctcatc acctagttta acaacatctt cgactttatt
    10441 gacacgatcg tttgctaatt gggaaatatg gacaagtcca tcttttcctt tgatcaagtt
    10501 gacgaatgca ccgaattttt cgatacggac aactttccct agataaactt caccaacttt
    10561 gacttctttg gtcaaatctt cgatgatctt gatagctttt ttgatcattt ctgcatcagc
    10621 tgaagcaata cttacttttc catcttgatc gatatcgatt ttcacaccag tttcatcgat
    10681 gattccgttg atcgtatcgc cgcctttacc gataacatct ttgattttag caggttcgat
    10741 ctggatcatt tcgatttttg gtgcatattg gcttaattct tcacgtggag cagcaatcgt
    10801 tgaagtcaat tcttctaaga tttccatacg tgcttgtttt gcttgagtta atgcttcagt
    10861 taggatttgt tctgtgattc cttgaatctt gatatccatc tgtaaagcag tgataccatc
    10921 ttttgtaccg gcaactttaa agtccatatc gccaagatga tcttccagcc cttggatatc
    10981 agttaggatc gtatagtttt caccatcaga aacaagtccc atcgcaatac cggcgactgg
    11041 cgctttgatt ggtacacctg catccatcaa tgctaatgtg ccagcacaga tacttgcttg
    11101 ggaagaagaa ccatttgatt ccaatacttc tgctactaaa cggatcgtat aaggaaattc
    11161 ttcttctgaa gggattactt gtgctaacgc acgttcacct aatgcgccat gtccgatttc
    11221 ccgacgccct ggagagcctg cacgtcctgt agaaccaaca gaaaattgag ggaaattgta
    11281 gtggtggatg aatcgtttgc tgacttccac ccctaaacca tcaatgattt ggtgctctcc
    11341 tagaggtgcg agtgtacaag ctgataaagc ttgtgtttgt cctcgtgtga acaaacctga
    11401 tccatgtaca cgtggcaata agctgacctc tgatgacaat ggacggattt catccaattt
    11461 acgcccgtca ggacggatct tatcgatggt gatcaattca cgtacgacat ctttttcaag
    11521 atcttctgtg atttgtttaa cttctttcaa caagtgatct tcatcttcat gacctgcaaa
    11581 tttctcagca taagcttcgc ggatatcgat cttcacctgc tcgatattat cttcgcgagc
    11641 aagtttttct tcagtcatta ctgctgcttt cattgtagcg taagaagcat caaagatttc
    11701 ttttttcaat acttcatcaa cttgcagtaa agtcacttcc attttttctt tccctactgc
    11761 ttgaacgatt tcttcttgga aagcaactaa ctctttgata gcgtcaaaac caaacagcaa
    11821 tgcaccaagc atgtcttctt ctgaaacttc tttcgcgccg ctttcaacca tattgatggc
    11881 ttgtttcgtt ccggcaacag tcaattcgat atctgtttgt tctgcttgtt ctactgttgg
    11941 attcaagacg tactcgccat ttacacgacc aacttctacg cctgcgattg ggccgtcaaa
    12001 tgggatatct gagattgata gtgctaaaga agaacctagc attgctgcca tagctggcga
    12061 gcagtctgtt tctacactca tcacgatgtt cgttacttgg acttcattac ggaagccttc
    12121 tgcaaacatc gggcgaattg gacggtcgat caaacgggca gtcaatgttg cttccgtact
    12181 tggacggcct tctcgtttga tgaaacctcc agggattttc cctgctgcat acattttttc
    12241 ttcataattg atcgttaatg ggaaaaagtc tgtatctttt gcttctttag aggccacagc
    12301 tgcacttaag actactgtat ctccataacg gactaaaacg gctccgtttg cttgttttgc
    12361 tagctgaccg acttcgattt gtaagggacg gccgccccat gtcgttttga atacttgttt
    12421 ttctgacata acttctcctt ttccttctcg tgaaagcaag acgctactaa acaaatgaaa
    12481 actgccgaaa gccgtctttt gagcagcttt catttggtta gtaggagtcc atctagcttg
    12541 atcacggaat tttacttaat tgatatacga gtaaaaaaag tgagattcat gtgaatccca
    12601 ctctttttga ctaaaattaa cgacgcaagc ctaaacgttt gatcaattcg cggtaacgtt
    12661 gaacgtcagt tttacgtaag taagctaaca agttacggcg gtgaccaact tttttcatta
    12721 ggccgcggta tgaatgatgg tcttttttgt gcacgcgtgc atgttcattc aagtggttga
    12781 tttcttcagt taatacagcg atttgtactt ctggagaacc agtatcccct tcatggcgag
    12841 cgtattcgtt gatgatttca ttcttgcgtt cttttgaaat tgccatttct ttcacctctt
    12901 tcgattattc ccctgcgact gagtaaaacg ttggtgattc gcttaaccaa gtggcaggtc
    12961 atgtgcctag agcacacagc tatactttac ctgaaaccgg gttgaaaatc aagtagttaa
    13021 tcattaagaa aaggtagttt tcaaacaatc ttactactac ttttccattt ttgtggtaaa
    13081 ctataatgcg aaaatagact tgaaacacag tcttttaaga aaggggtaca tattccatga
    13141 ttacaatgga tgatatcatt cgtgaaggaa atccgacctt acgcgaagtt gcaaaagaag
    13201 tttctcttcc attaagcgaa gaagatatct ctttaggaaa agagatgctt gagttcttaa
    13261 aaaacagcca agatccaatc aaagctgaag aactacactt acgaggcggt gttggcttag
    13321 ctgctcctca attagatatt tctaaaagaa tcattgctgt tcacgtacca agtcctgacc
    13381 cagaggcaga tggaccttct ctaagtactg ttatgtataa tcctaaaatt ttgagccatt
    13441 ctgttcaaga tgcttgttta ggggaaggtg aaggctgttt atctgttgat cgagaagtac
    13501 caggatatgt tgttcgccat gccaaaatca ctgtgtctta ttatgatatg aatggtgaaa
    13561 aacacaagat tcgtttgaag aattatgaat cgatcgtcgt tcaacatgaa atcgaccata
    13621 tcaacggtgt gatgttctat gaccacatca acgatcaaaa tccatttgca ctaaaagaag
    13681 gcgtattggt gatcgagtag agaattggca ggttccttcg atactatgct acaagaaagc
    13741 tttataaaaa aggggagtgc tcaaaagctg cacttccctt ttttatgttt ctccactaat
    13801 cgaaatttag atagacatct agaaatcgca attccaaaaa attctgtgta ttggatacgc
    13861 atcttttctt attttttctt atttcttcca tatgggtgtt tatctcagag atgatagaat
    13921 agtttctagg ataaaaagta gcagctacga tgttatcctt cgtagaggat tcctgcttca
    13981 gctagttttt gtttgatgtt tttcagcata tgcttttctg ggtagcggat cgtatgcaga
    14041 tggatgccgc ctgttaattc ggataacaaa gtagcattac ttttttgata acgtctcata
    14101 aaggaatcga tatcttgtgg cgttttgatg tgcaaagttc ctgctaactc accgtaaagg
    14161 ggatgttcca caattacatc aatgatttca ccaccatttt caacgattag tctcagttct
    14221 tcttctgttt gatcttttcc atgctggaca gcgattttac tgatgtgccc agtattggtt
    14281 tcttctgttt cgaggatata acctcttgct gttgccacga tacttttacc tgcagctcgt
    14341 agtaaagcaa tatcgcctac aatgatctga cggctgactc caaaagtttt cgcaaacttg
    14401 ctagcactca ctggtttttc tgtatttgcc aaggtttgca tgatttgttt tcgccgtgtc
    14461 tctccttcga tcacacttat tcctccttca ttttgttttg gtattcgcgc gagtgtttca
    14521 tcaaatcaac atacgtgtct gttattgttt ccttatatcc cttatttttc agcagactaa
    14581 caactttatc caatacttgc tgctctcttt ttgcatcata aactgcttgg ttttcttctt
    14641 ttttcacttg tcctatttta gttaccgtat ccattctttt ttctaataaa gcaaccaact
    14701 ctcgatcgat catatcgatc ttatgacgta atgtttcaag agactcttct gttagttctt
    14761 cctctactgt cttgatgata cgagcaggat ttcctgcaat cactacattg tcgggaaaag
    14821 atttggtcac aaccgaacct gcgccgacta ctacgttgtc ccctagagtg acacccggcg
    14881 tgacgataac tcctccgcct aaccaaacat tattaccgat tttaatgggt tttgcgtact
    14941 ccagaccgct gttacgtttc actggatgta gtggatgcgt cgccgtgtaa agctggacat
    15001 tcggagcgaa catgcagtta tcaccgattt caatcgtgct gacatctaaa aatgtacaat
    15061 tgaaatttgc ataaaaattc tccccaacaa atatattata tccgtaatca aaattgataa
    15121 ctggctccat atagattttt ttccctgtac ggccaaaagt ctctttcaac aattgggatc
    15181 gcagttccgc tgattctgct tggttgatga tttggctttg acttcttgca aacatacggt
    15241 cggcaaccag ctcaggatca ttggcaaaat aaagctcgcc tgcaatcatt ttttcttttt
    15301 cggttttgaa ttcagtcata atctgctcct aattcttgta tttttttgaa aacaaccgct
    15361 ccgtcttctt gaataaacgt ataaggctcc gctaaataaa caggcgtttg attgattact
    15421 aagattttgg ctgacggctg gcgaaactgt accagatcac aaaacggatg aacttgaaaa
    15481 ctcgttccaa caatgacgat cagctctgct tggctgacgg cataagccgc ctgctccatg
    15541 actccatctt gaaacccttc accatataac acgatgtctg ggcgtatttg tcctccgcat
    15601 gcttgatgtt tgtcgctgtg aagatattct ttccagtcta ccgtttgttg acattttcga
    15661 caatgacatt gatacagact cccatgaaaa ttgacgagtt gcgggctttt agcctttgcg
    15721 tgcaaaccgt cgatgttttg ggaaacaacc caaacatttt tttctttcgc tagatgtgct
    15781 atttccaaat gaatgatatt gggttttgct tcaggatgat aaatcttttt gacaaattga
    15841 tagaatttat ccggttcatt caccattgct tgatgactca gcaagtattc cggctgctcc
    15901 atcccgtggt agattcctga caaagatcga tagtctggca ctccagaagg tgtggatacc
    15961 cctgcaccgg tcaaaaatgt aatttgctga taagctaata tctcttttgc tgcttcgtct
    16021 actgttaatt gtttcatgtt ttgtcacctc actttccatt atagcccata ctcgaacaaa
    16081 tttattgttg aaaagtcaga aaaatgggaa taaaaaagtg ttatgggcat ttgagcaatt
    16141 tatcacaatg ttcactgaca aaagaatgaa aacgtgttac aatactgctg tataaaagtg
    16201 aggtgaatcg atatgttacc attctttatt tattggggcg ttattctggc ttgtatcgcc
    16261 tggttagcgt taagcgttta tttctctgtt ttttatcttg tacgcaaaga aaatggaaat
    16321 ctttgggctt ttgctttatt caacgtgatt gccgcaattg ttttagccat tacattagcc
    16381 gtatatcgaa catggggctg gggaatcacc caatactcaa gtttgattta tctaatatta
    16441 gccatttatg gcgtcgttgt tcttttgcaa gcgatcctag gacgtgagcc aaagaaagcg
    16501 gcagcttaaa tgatcgagat ggaactggac acaggaaatt ttctgttcta gttctttttt
    16561 tattgtatta catacatttt tgtgtataat tatactatcg tttgcaatgg atagatgatt
    16621 cacattttga ttgttttttc ggtaaaagta aagatttcta tatttatcag tattttttca
    16681 aaaaccagca gttatagatt gacaaagcct ctcgagtatc gtaaactttt tttgtataaa
    16741 taactgaata cgagatgcct caatcaatga ggtagaggtc gcgagaatca ttaaccctgt
    16801 ggagtgaagc aaacatggag aagcaggaat agggaggatc gccgaaatgt gcactttttt
    16861 gcttggagtg tatgttggga cgcaagttaa gagcttgcgg actgtcttag cagtgatgct
    16921 aagttgcgct atgttttgtg agaggtttat caccttatgg aattttagcg gcctttttat
    16981 atctataaat cggtcgcttt ttattttttc agataaagct ttaccgcatt tcatctagac
    17041 cgctcgtgta tcatataatc agaaagggag aaaaaaatga aaaaaaatat ggtttcagtt
    17101 gccgtactat ttgcttttgt cttctcacta ttcagtgtgg gatctctggc aaatgcagat
    17161 gaaaaaacac cgagcgatga gtttcgcgta ggtatggagg ctgggtatgc acccttcaac
    17221 tggtctcaac aaacagatga gaataatgcc ttgccaattc aaggccaaaa tagttacgcc
    17281 ggcggttatg atgttcaaat cgctaaaaaa gtagcagatg gtttagggaa aaaattagtc
    17341 atcgtccaaa cgaaatggga tggtctggct cctgcccttc aatcaggcaa gatcgacgcg
    17401 atcatcgccg gaatgagccc tactgctgaa cgacgaaaag aaattgattt taccgatcct
    17461 tattacgaat cacaattagt agtagtagtt caaaaagata gcaaatatgc aaaagcaaaa
    17521 agtttagcag atctttctgg agcaaagatc actgctcagt taaatacatt ccactatact
    17581 gtgatcgatc agataccaga tgtgcagaaa caacaagcaa tggataattt ctcagcaatg
    17641 agaacagctt tagcttctgg aatgatcgat ggttatgtca gcgaacgtcc ggaaggtgta
    17701 acggcaacta gtgtgaacaa agacttggaa atgcttgaat tcagcggtgc agatggcttc
    17761 cagacaaacc cggaagatgt tcagatttct gttggtatgc gtaaaggcga cccggatatc
    17821 caaaaagtaa accagattct ttctggcatc tctaacgatg aacgaaccaa aattatggac
    17881 caagcagtca aagatcagcc tgctgcaact gatagtgaag aaaaacctgg catcatttct
    17941 gatttcacta cgatttggaa acaatacggc aatatgttct tacgaggtgc tggacttacc
    18001 ttgttcatcg cattgatcgg gacagttgtc ggtactacac ttggattact gattggtgtc
    18061 ttccgttcgg tacctgaatc aggaaatgca ctgactcgct tcttccaaaa aatcggaaat
    18121 gcacttcttt ctatctatgt cgaagtattc cgcggaacac cgatgatggt acaagcaatg
    18181 gtcatcttct acggtctggc actcgctttt ggcatttcat tgaaccgaac gattgccgct
    18241 ttgtttattg tctctctcaa tactggagct tacatgacag agatcgttcg tggggggatt
    18301 tttgcagtag atgaagggca gttcgaagct gcgcaagcca ttggtatgac ccatggccaa
    18361 acgatgagaa aagttgttat tccacaagtt ttacggaata tcttgccagc aacaggaaat
    18421 gagtttgtta tcaatatcaa agatacagca gttttaagtg taatcggcgt agctgatttg
    18481 ttcttccaag gaaactctgc ttccggtgcg aatttccaat tcttccaaac atttacgatc
    18541 gtcgggatca tctacttagt catgaccttt acgatcacca gaatcctgcg ggcggtagaa
    18601 aagaaaatcg atggtccttc agcttatacc aagcttgaag aaatcgacaa ttcaaatttg
    18661 caggaataag gaggaagaat catgaatgaa aaaattattg aaatcaaaca tctaagaaaa
    18721 agcttcggtg aaaatgaagt attgaaagat atcagcgtaa cagtcaataa aggtgaagtt
    18781 gtgacgatca tcggttcttc cggttctggt aaatctactt tcttgcgctg tatcaattta
    18841 ctggaaaaac caacaggcgg cgagatcatt tataatggag aaaatgtatt agctcctaaa
    18901 tataatttac ctaaatatcg aacgaatcta ggtatggttt tccaatcctt caacctgttc
    18961 aacaatatga atgtcttgga aaactgtatg tctggtcaaa caactgtcct gaaacgagat
    19021 aaagaaactg ccaaaaaagt agcaatcgaa aatctggaaa aagttggtat ggatcgttat
    19081 atcgaagcca aaccagcaca attatctggt ggacagaaac agcgtgtcgc aattgctcgg
    19141 gcattatcaa tgaatccaga tgtattgcta ttcgacgaac ctacttcggc gttagaccct
    19201 gaaatggttg gcgaagtgct taatacgatc aaagacttag cacatactgg cttgacaatg
    19261 cttatcgtga cgcatgagat ggaatttgca aaagatgtat ctgaccgtgt catttttatg
    19321 gataaaggtg tgattgcaga agaaggtaca ccagaagata tctttgtcca tccgaaagaa
    19381 gaacgtacaa aagaattcct ttcacgtatt ttaaatgctt aggatcaata gctgattggg
    19441 acaaagagct gcggtgttta ccgcagttct tttttatgaa ttactcataa aaggtaaatt
    19501 tctgaaaatt ttggaatctt agttgtgttt ttcagaaaac tctcttaata tggaagtaat
    19561 taaacttttt tagttaggat gatttaaaaa tgaatgaaga gcaagaactg cagcgtggac
    19621 tgaaaaatag acatgtccaa ctgatttcta ttggcggagc gattggaacg gggttgtttt
    19681 taggttccgg aaagtctatc cagctagctg gcccttcgat attgctcgcc tatcttatta
    19741 ctggatgcat ctgttttttc attatgcgtg cgttaggcga acttctgtta tcaaacacca
    19801 ataaccattc ttttctggat tttgttgcag aatatcttgg caaaaaagcg gctttcatca
    19861 ctggctggac gtattggttc tgctgggtat cgattgcaat ggccgattta acagccatcg
    19921 gaatgtatgt acgctactgg gcgcctggtg ttcctcagtg gcttcctgaa ctgattgcat
    19981 taggtcttct tctttgcttg aatatggtgg ctgtctcatt gtttggtgag ttagagtttt
    20041 ggtttgcatt gatcaaagtt gtagcgatca ttgcctttat cctcgtagga gcttatatga
    20101 tcctcaccca ctatacgaca gatattggca cagccagtat cacgaatcta tggtctcatg
    20161 gcggattctt tccaactggt gcaaaaggat ttatcttagc tttccaaatg gtaacctttg
    20221 cttttgctgg gatagaatta gttggattag tcgctggaga aacagaaaat cctgaaaaag
    20281 tgttgccgga agctatcaat aatattccta tcaggatcat cttattttac ttaggatctc
    20341 tttttgtcat tatggcaatc tatccatgga acagcttgaa tccagataac agtccatttg
    20401 tagaagtatt ttcggaaatt gggatcacga ttgctgcttc cttgatcaat ttagtcgtat
    20461 taagtgcagc agcttctgcc tgcaacagtg caatatatag tacaggacgt atgcttcgtt
    20521 ctttagcgca agaaggcagt gcccctaaaa aattcaaaaa gttaacaaca catcatgtgc
    20581 cagggaatgc tttgacattt tctactatcg tcattttcat ttctgttatc ttgaattacg
    20641 tgatgcctag tgaagtattc acactagtaa gcagtattgc cactacttgt ttcttgttta
    20701 tctggagtat gcttgtctac acgcacatga aatatcgtaa aagtatcctc ggcaaaaaag
    20761 ctcattcatt taaaatgccg ttgtacccat ttagtaatta tctggtattt ctttacatgg
    20821 cctttgtgtg tgtcgtcttg ttcctaggaa aagatacgag aatcgcttta ttactaacac
    20881 ctgtgtggtt cttgcttcta ttactaatct atcatatgaa atatgaacgt aagaagtaag
    20941 aaagtagttg tgacagaagt ggtcagcttc gagaaataag aaggaattta cgaaaattgc
    21001 ttcttaaatt tttgtgaaat ttcggcttat ttcttggaga taaaagcttc tgtcccagcc
    21061 tcttttctat ttccccggaa acaaccgctg ataataggca tctgcttttt tataggaaaa
    21121 aatccaaata ccagatacaa aaaaacgtcc gaataacccg atcaacggta caaaaaagac
    21181 accggcaatc aagcataagt taatcatcat ggagataaga cttcgacggt cctttgacaa
    21241 aactctcacg acatgggaat ctggtttatt tgctttcatg atttgcctca tcaagatacc
    21301 aaaagaaaaa ctccacatcg tgtatactaa gacataagcc atctcaggcc aaaaagcttc
    21361 agggttacgc ccgacccaac tagtaacaga aggacataaa gtcagccaaa agagcaaaaa
    21421 gatattcgac cagaccactc ggtaattaat tcgttctgcc atctgaaata tacgatgatg
    21481 gttcacccag atcaccgcaa caaatataaa gctgatggta taagctaata atgtatttcg
    21541 gatgacccat aaagaatgaa agctagatgt attagggatc ttgatctcta atacaataac
    21601 tctcaaaaca atggctacca ctccatcagt aaatgcttct aatctcgact ttgtcacgat
    21661 gattcctcct cagatgattc agcgctttta ttttatcact tacgttatta aataaccatc
    21721 gttttatata gggaattttc tgaaaattgt tgcatatttt tcgaaatttt gttactttta
    21781 aaaaaaccgt aaaggagtta tgtatgacaa aaaaattatc atttaaagac tatcttttta
    21841 taggctccat gcttttcggt ctattttttg gtgctggaaa tcttatcttt cccgttcatt
    21901 tgggtcaaga agcaggcgct gctacctttt gggcgaatct aggtttcttg gttaccggta
    21961 tcggtcttcc cttcttaggg gtgattgcca ttggtgtatc gaaaagctca ggtgtatatg
    22021 aattagcaaa acggataaat caaacatatg cgatggtttt taccatcttg ctttacttag
    22081 ttatcggacc gttttttgct ttacctcgcc ttgcaaccac atctttcgag attggtttag
    22141 caccatttat cgatcctagc agacagacgc tatatctagc aattttcagt attgtatttt
    22201 ttgtgctggc ttggtggttt tcaagaaaac cgacaaagat attagattat gttggaaagt
    22261 tcctgaatcc tgcatttttg gttttattag gtgctttgct tctccttgct tttttgaatc
    22321 cactaggttc tgtaaatcaa gcgcctattc agccaaatta tcaagagcat gcttttttca
    22381 cagggtttac tcaaggatat aacacattag atgcgcttgc tgctttagca tttgggatca
    22441 tcattgtcac aacaatccaa aacatgggtg taacaaaacc tgctgaaatc gctaaagaca
    22501 cgatcaaatc tggtgcgatc agcattatat tgatgggaat catttatact ttgctcgctt
    22561 atttaggtgc tatgagctta ggtagctttg ctctaagtga aaatggcggg atcacgctgg
    22621 ctcagattgc tgatcattat ttaggtactt atggcagtat cttattagca tttatcgtta
    22681 tattagcttg cttgaagacc ggtattggtt tgattacagc ttttgcagaa acattcacag
    22741 atttgtttcc gcaaagaaat tacgcattct ttgttgcact tgctagtatc cttccttgtt
    22801 tagcggcaaa cgtaggcttg acgaatatca ttcaattttc gttgcctgtt ttgatgttca
    22861 tctatccatt agcaatgaca ctgattttac tagtgttagt tggtcctttg tttaagcagc
    22921 gtacggctgt ttatcgaatg actacttatt ttacattgat tgcttcgatt tttgatgggt
    22981 tgaacgcttg cccagaaact atcaaacaaa cacctattgt tcaaaatctt ttatatgttg
    23041 cggaaagcta cttgccgttt ttcaaattgg ggatggggtg gatcgtacca gcagttatcg
    23101 gttttgttat cggactgatt tggagtttcg ctaagaaaga agaagtagca gattgataaa
    23161 agaggttgtg aaagagacgt tcagccttga gcaataaaaa gtaattttga aaaatggctt
    23221 ctcac
//
LOCUS       DAFBSV010000044        22856 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.045, whole genome shotgun sequence.
ACCESSION   DAFBSV010000044 DAFBSV010000000
VERSION     DAFBSV010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22856
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.045"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(104..1336)
                     /locus_tag="LLB18_001571"
     CDS             complement(104..1336)
                     /locus_tag="LLB18_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBK5244577.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1591..2160
                     /locus_tag="LLB18_001572"
     CDS             1591..2160
                     /locus_tag="LLB18_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK5244578.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2338..2778)
                     /locus_tag="LLB18_001573"
     CDS             complement(2338..2778)
                     /locus_tag="LLB18_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBK5244579.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2936..3700
                     /gene="map"
                     /locus_tag="LLB18_001574"
     CDS             2936..3700
                     /gene="map"
                     /locus_tag="LLB18_001574"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBK5244580.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3732..4655
                     /locus_tag="LLB18_001575"
     CDS             3732..4655
                     /locus_tag="LLB18_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBK5244581.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            4731..5870
                     /locus_tag="LLB18_001576"
     CDS             4731..5870
                     /locus_tag="LLB18_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HBK5244582.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            5863..6663
                     /locus_tag="LLB18_001577"
     CDS             5863..6663
                     /locus_tag="LLB18_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBK5244583.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            6663..7490
                     /locus_tag="LLB18_001578"
     CDS             6663..7490
                     /locus_tag="LLB18_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBK5244584.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            7468..8202
                     /locus_tag="LLB18_001579"
     CDS             7468..8202
                     /locus_tag="LLB18_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBK5244585.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            8302..9168
                     /gene="rfbA"
                     /locus_tag="LLB18_001580"
     CDS             8302..9168
                     /gene="rfbA"
                     /locus_tag="LLB18_001580"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBK5244586.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            9182..9754
                     /gene="rfbC"
                     /locus_tag="LLB18_001581"
     CDS             9182..9754
                     /gene="rfbC"
                     /locus_tag="LLB18_001581"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBK5244587.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            9776..10804
                     /gene="rfbB"
                     /locus_tag="LLB18_001582"
     CDS             9776..10804
                     /gene="rfbB"
                     /locus_tag="LLB18_001582"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBK5244588.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            10902..11753
                     /gene="rfbD"
                     /locus_tag="LLB18_001583"
     CDS             10902..11753
                     /gene="rfbD"
                     /locus_tag="LLB18_001583"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBK5244589.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            11787..13820
                     /locus_tag="LLB18_001584"
     CDS             11787..13820
                     /locus_tag="LLB18_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244590.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYIAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            13864..15143
                     /locus_tag="LLB18_001585"
                     /pseudo
     CDS             13864..15143
                     /locus_tag="LLB18_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
     gene            15353..16159
                     /locus_tag="LLB18_001586"
     CDS             15353..16159
                     /locus_tag="LLB18_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5244591.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            16171..17391
                     /locus_tag="LLB18_001587"
     CDS             16171..17391
                     /locus_tag="LLB18_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5244592.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            17381..18967
                     /locus_tag="LLB18_001588"
     CDS             17381..18967
                     /locus_tag="LLB18_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBK5244593.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            19006..21144
                     /locus_tag="LLB18_001589"
     CDS             19006..21144
                     /locus_tag="LLB18_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBK5244594.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(21512..22495)
                     /locus_tag="LLB18_001590"
     CDS             complement(21512..22495)
                     /locus_tag="LLB18_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBK5244595.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
BASE COUNT         7177 a         3897 c         4711 g         7071 t
ORIGIN      
        1 aaaaaacggt ggggttgttt agcgaaataa aggatctaag ccaatagctt agatccttta
       61 ttctatgctt tatattattt tttgcatgtg tgcgaaagta tactcaagcc caatcgccat
      121 ttcggaaaat cggtactgta gagccatctt cacggattcc gtcgatatcc atcttgtcag
      181 atcctaccat gaaatctacg tgggtttgac ttctattcaa tccagcttct gctaattctt
      241 catcggacat ttctgtaccg cctttcacac tgaaggcata agcagaacct agtgctaagt
      301 gattcgatgc gttttcatca aataatgtat tgaaaaagat gatgccagat tgagaaatag
      361 gtgaagggtc aggtacaagt gcgacttctc ctaaacgacg cgcaccttca tctgtatcaa
      421 gcagttttgc taagacatct tctccttgtt cggcagaaaa atcaacaact tttccatctt
      481 taaaagtaaa tttcataccc gagatgatgg tgccagcata actcagtggc tttgtacttg
      541 aaatgtaacc atctactcga tgactgtcag gtgctgtgaa cacttcttcc gtcggcatat
      601 ttgccatgaa tttttctcca cgagcattat agcttccagc gccttcccaa agatggtttt
      661 taggcaatcc gataatgata tctgtaccgg gagcagtata gtgaagggca gaaaattgtt
      721 ctcgattcaa ttcttctgct ttttttgcta atttttcatc atgcttcttc catgctaaga
      781 cagggtcttc ttcatagaca cgagtcgttt tgaaaatctg atcccataat gcctcaactt
      841 gtttttcttc tggcagttct gggaagactt ttgctgccca ttgtttacca gccgcagcca
      901 cgacagtcca actgacttta tttgcttgag ttgccttgcg taaattcatt agtgctttgc
      961 cattcgctga ttgataagac gctactcgat ggctatctac accagcaaat gcatcgggat
     1021 cggcagaaac aacgctgatc ctgcttgctc ctttttcaag ccattcatcc gcttgatcga
     1081 ttttagattg tggtacattc tcaatacgat ccgttgcagc atgtaaaaga aattctcttt
     1141 ggatctggtc gtcagtccat tgaacgataa cctcagcggc tcctagttta taagcttctt
     1201 gtgtgatcaa tcgagcaagg ggtgcctgtt ccacgctgat ctgtaaaaca actgtgtgtc
     1261 ctttttctgt ggctacgcca gtttctgcaa ttaagcgtgc atattttttt agaagttcat
     1321 taaaatcaga taacataata aaaattcctc ctcaccattt tttctggtaa ctattagcat
     1381 gataccattt aattatgatt caaacaatga ggctttaaat aaaaaaagga ggttattttt
     1441 ttaaggttaa gtttcatgat atatgttact acttgctatt tcagcttgtg aagaaaatca
     1501 aaaactaatt ttgcatatca aaaaaaacat gttacaatga aattaatcaa tggtggaagc
     1561 gttataaaaa aattaaggag attaaaaaat atggcaagaa aaaagacgat tactagagaa
     1621 cagattttgg cagctgctta tgaagtagct gccaccgatg gatttacacg atttactgcg
     1681 agaaacatcg cgaacaaaat gaattgttcc acgcaaccga tttatcttga gtttaaaaat
     1741 atggatgact tgagacaagc tctttttgag cagatctatg atcatttaca atatgaagtg
     1801 ttcactgttg agcatacagg gaatacgatt atcgatcttg cttttaatta tatccatttt
     1861 gcaagaagag agaagaagtt gtatcgttca ctgtacttag aagaatatgg tggaggaaaa
     1921 gagatgcaga atttctctta tacttacttt gtgaatacag tgaaacgcga tccagcttat
     1981 gtgaatcttt cagaagagca gatcgaatct ttgtataatg ggacatggat catagctact
     2041 gggatcgcag ctttgatgtc ttcaagcatc atccatccaa ctgatgaaca gattgaaaag
     2101 atgatccaag acagtataga tgctatcttg aaattcaaag aaccaatcga aatcgattga
     2161 atatactcaa aagttccaca aatcagtagg taacaagaga tgtgtcaaaa taaggaaaag
     2221 ttcgtttttc ttacagcgta tgcattttta actcccgaag aactcttcca tgaatgcaat
     2281 gaataaaaga gccatacaga ttgaataaat ctggatggct cttttattgc aagtatatta
     2341 aatttttgcg actagttctt tagcgaaagc ttctaaattt tcgatatctt cttcttcagc
     2401 attcagatcc actttaacat tttcggctcc ttttgatgcg cctgtttttg caaaagcagc
     2461 atcgaaatca tccaccgatt tgcagaattc atcgtaaaaa gtatcaccag atccgcagac
     2521 accgtaaatt tttcccaata gatccaattc ttgcaagtct tcataaaagt ctacgatctc
     2581 atcaggcaga tcgccatcat cgtatgtata agtagctact acgcaaatat ctgcctcctc
     2641 gaattcatct gcatctactt gggtacattc gttgatttcg acttcgatat ccagattttc
     2701 aaatgcttct gcaacaatat cggcgatttc ttcagtgttt cctgtcatgc tagcatatac
     2761 gatttttgct aaagccatga tgtgcctcct cgtttataat tatttaacaa ttatgaatta
     2821 taccaaaaca tcattgaaaa gaaaataaaa cctagagaca cctggggaat gtcatttggc
     2881 taaatgtatg ccgctatgtt aaaatgagag ggatttgtaa aaaggagacg aaaatatgat
     2941 tactttaaaa tcagcacgtg aaattgaaat gatggcagaa tctggagctt tattagcaga
     3001 tgtacataaa aatctgcgtg attttataaa accaggaatc acaagttggg atattgaggt
     3061 atttgtcaga aactatatcg agagtcatgg cggaattgct gcgcaaattg gctttgaagg
     3121 gtatgaatat gcgacttgta tcagtataaa tgatgaaatt tgtcatggat tccctcgtaa
     3181 aaagcctttg aaaaacggtg atttggtaaa agtcgatatg tgtatcgatt tgaaaggcgg
     3241 catttctgat tcttgttggg cctatgtagt tggagaatct acacctgaga tcgaccgatt
     3301 gatggaagta acgaagaaag ctttgtacat cggtattgag caagcacaag tagggaatcg
     3361 gattggtgac atcggtcatg ctatccaaac ttatgtagaa ggcgaaaatc tagcgatcgt
     3421 tcgtgatttt attggtcatg gcgttggtcc tacgattcat gaagaaccag cagttcctca
     3481 ttacggagaa gctggaaaag ggttgcggtt gaaagaaggc atggttatca cgatcgaacc
     3541 tatggttaat accggaactt ggaaaatgaa aatggatcct aacggctgga ctgcgtatac
     3601 aagagacggc ggactttctt gccaatatga acatacattg gctattacta aagatggtcc
     3661 aagaattttg acatcacaag gagaagaagg cacttattga tctatccagt caataggtac
     3721 gggagaggta catgaaagtt tggaacaaaa taaaacaaaa tgaaaatctg atgcgcttta
     3781 ttgagacgac tcaaaagcgc atcactgatt cagaaatgag tacgacctct gtcgtcgttg
     3841 cttattattt actcttgtct ttatttccat tgattattgc ttttggtaat attttaccgt
     3901 ttctccacat cgatcaagag actgtactga cctatttacg agaagtgatt cctgagaccg
     3961 tttaccagtt tatcggtcct gcaatcaaag accttttgac acaaagttca ggaggcttgt
     4021 tatccgtttc tgcattagcg gctttatggt ctgcaagtca aagtatcaat gctttgcaaa
     4081 ttgcgatgaa taaagcgtat ggcgtagaaa atagaaaaaa ttttttgatc gtccgtttct
     4141 tctcactaat tgtcattgtc ttgttcatga ttgctattag tggggtaact atcgttcttg
     4201 ggttgggaca gctgattttg gatgctattc agccaatcgt acaaataccc gtgaacttta
     4261 tcgatcagtt ccaaactttg aagtggccaa tcacattggt agctttattt gtcatcatgt
     4321 tcttgattta tttaattgtc cctaatgctc agttgaagtt gaagacgatc attccgggca
     4381 cgatcttcgc tactgtcggc tggatgctgt tatcacaagt gtttagtatc tatgctaggt
     4441 attttgcaac gaggatcagc ggttatcaga tcataggaag ttttattgta ctcatgcttt
     4501 ggcttaattt tgctgctacg atcatcattt tgggcggaat catcaatgca gttgttcaag
     4561 aatacgtgac gggtcatcaa atcaaaaaac gtcgagatcc aagccgaaaa tggttcaata
     4621 aattgaaaac taaattttct cataaaaaaa agtagaaaca agagttctta ttgtaaattt
     4681 atatcagtaa tttataataa ttatgactct taattaaagt aggtgcccat atgcttgttt
     4741 cttttagtat ggttataaga ttttttctga caattttatt atcactgata ttaacacctg
     4801 tattcaaaat catttcagta caaacaggta tggtcgacaa accaaatgaa agaagaataa
     4861 ataaagttcc aatgccttca gcgggcggac tgcctatctt tatttcattt gttatatcga
     4921 ctttattctt attccgtaaa attatccctc aatcgtatat tgtaccgatc ttgattgctt
     4981 ctttagtaat catagtcaca ggagtgctcg atgataaata tgagctgaca cctaaacaaa
     5041 aaagtatagg gatcttgatt gcttctctta ttatttattt tgtagcagat atacgtattg
     5101 attccttcac gcttcctttt attggatata tccaactagg ctggcttagt tttcccgtaa
     5161 cgattttttg gatcttcggt atcacgaatg cggtcaatct gattgacggt ttggatgggc
     5221 tggcggcagg gatttcattg atcggtttaa ttacgatagg aatcattgga tattttttcc
     5281 tccatgcttc tacagtgtat attccagttg ttattttctg tcttgtagca agtattatcg
     5341 gtttttttcc ttacaatttt tatccggcaa agatttattt aggcgataca ggagctctat
     5401 tcctagggtt tatgatggcc gtcctttcac tacaagggct gaagaacgtg acttttgttt
     5461 catcgatttc tttgctgatc gtcatgggag tgccggtaac agacacgttt tttgctatca
     5521 ttaggagaaa agcaaaccgt gtttcttttt ctacagcaga taaaaaacat cttcatcacc
     5581 gactaatcag tttaggcttt actcataaag gtgctgtcct gacgatttat gcgatggctt
     5641 tgatgttttc tttcacagct atggtcatga attatactgg aagaatcgga acgatcatat
     5701 tgattattgc catgttgttt gctgcaattt tattatttga attgattggt ctgatcaatg
     5761 agaaacatca gtttatttta aaaacattgc gatttttagg gaataaagag taccgtacgc
     5821 aagtaaaaca gaaatatttg aagaaatgga accgtcatat agatgaataa caaattaaac
     5881 cagccgatcc ttattagtat tgtgacggca aacagtgata aaatttttcg gacactagat
     5941 aattttattt caactgtaaa agatgaaaca gcagtaaaaa tccgaatttt tgacaacaat
     6001 tcacttcccg agtacaaaaa aagactaaca gagtatagga aatatcccta catcgatatc
     6061 tattttcatg atgaaaattc cggatttggt tatggacata atcacaatct gatagctagc
     6121 gattctcgct atggcattat ttgtaaccca gatattttag tggatgaaga gacagttaca
     6181 gcattggtct tgttattgaa agaacatccg gaatgtgcga tgttagcacc taagattctt
     6241 aatgaagatg gaacaactca gcacctcatc cgtgagcagc tggctgtttt tgattacgtt
     6301 ttgcgctttg tgcctttcaa atgggtcaaa aaaaagtttg acaaacgact ggctgtgttt
     6361 gaatgccgag gattgcctac tgatgctaat agttatgtac ggatgatctc aggtagtttt
     6421 atggtagctg atattgataa atttaaagag ataaaggggt ttgatgagcg tttcttcatg
     6481 tactttgaag acaacgactt gtgtttgagt tttgaaaaag caggttacaa gttattgtac
     6541 acaccctttt atgcagttat ccatttttac gggaagggtg cgcatcgaaa tgcaaaactg
     6601 tttcgcgtgt ttttgacttc tatgatgaaa tttttcaata agtgggggtg gcgttttttc
     6661 tgatgaaacc agaaatatta gtagtcgttg tgctttatca gcaactattc agtcaatctc
     6721 cagcttatgg accattaagc aaagcactta gcgaaaagca aattcagctt attatttacg
     6781 ataatagtcc tcaaaggcag caaaatgagc tgtttgaaaa agaaaatatc gtttatcatc
     6841 atgatccgca aaatcctggt ttagcggtgg cttataattt tgcgttgtct caagcagatg
     6901 aaggaacacg ttgtctcgtc actctggatc aggatacgag gctagtcgac gattattttg
     6961 aactattgcg taaagtaacc tttacagatg aatgtgttgc tgcagttccg atgatttttt
     7021 ctgggagccg acaagtttct cccctatatt cagatcgtta tatcaatcgt acagctcaag
     7081 cagtagaagt tgaaggccca acagctgaac gaatcatggc aatcaattca ggtgttgcct
     7141 ggtctgtcaa atttctaaaa aagattggcg ggtttaatcc tgctttttct ttagattttt
     7201 tggatcattg gctgttttgg aaagtggatc agttggaaaa aactgtggag atccttcctg
     7261 tacgaatgga acatgatctt tcggttttag actatgaaaa agtttcaagt aatcgatacc
     7321 gttctatttt acaagcagaa aatcgatttt atcatgaata tgatcaaagg catttatcca
     7381 gtcaccgacg acaattattg ttaagaacag ctaaacagtt cttgaccgtc aaaaaccggc
     7441 atatctggcg gatgactttg cgctcatatg ttaagaattg gaaggtgtga attcgtgcgt
     7501 tcggtttgta tagctacctt taatggaggc agatatttaa gagagcagtt agatagtatt
     7561 ttatctcagc tttcagcaga agatgaagta gtcatttctg atgatgggtc agtagatgat
     7621 acatgggata tattaactga atacgcagaa aaagataagc gaatccagct tttttcgggg
     7681 cctcgtcaag gattgatcgc taattttggt tatgcgatcc agcagacgaa aggagatcta
     7741 atctttttgg cagaccaaga tgatgtttgg ttggagacaa aagtgaaaaa gatcactgac
     7801 tattttgagc agaatccgga tcagctagta gtagtttctg atttaatcat tgtggacagc
     7861 gagctgcaag agatccatga ttcgtatttt tcgtttcgaa attccaaaga aggatggctt
     7921 aataatgtga taagaagtca ctatattggt gctggtatgg ctttccggtc ttctttaaaa
     7981 cccgatattt tgccgatccc gtcagaagtg ccgatgcatg atatgtggat tggtttgctg
     8041 ggaggaaaga agactgggtt cctaagagaa ccgttaactc tgtaccgaag acatgattta
     8101 aacgcgagtg agattgaaac acattctaaa ttacggcaaa aaatttcttg gcgtgttcat
     8161 ctgattacgg cgttgatcaa acgaaaatgg tttaaacgtt gataaaagat gtttaaatcc
     8221 ttaatatttc catgacaaat ataacaattg atgagataat aacaaagtga aatttgaaat
     8281 caaaaaggag agcagatatc catgaaggga atcattcttg ctgggggcag cggaacacgt
     8341 ctgtaccctt taacaaaggc aacatcgaaa caattgatgc cgatttatga caaaccaatg
     8401 atttattatc caatgtctac tctgatgttg gcgggaatca aagaaattct gattatttca
     8461 acgccacaag atacaccacg tttcaaggaa ttatttggaa acggaaatga tttaggactg
     8521 cagatcgaat atgcagtaca agaaagtcca gatggattgg cacaagcgtt tatcattgga
     8581 gaagaattta ttggagatga tagtgtctgc ttggtattag gggacaatat ttactatggt
     8641 ggcggtctgt ctaaaatgtt gcaacgagca gcttcaaaag atacaggcgc gacagtattt
     8701 ggctatcatg tcaatgatcc agaacgcttt ggtgtagtag aatttgatga gaatatgcaa
     8761 gctttgtcga ttgaagaaaa gcctgctcag ccaaaatcaa attacgctgt aactggcctt
     8821 tatttttatg acaatgaggt aatttctatc gctaaaggta tcaaaccttc agaacgtgga
     8881 gaactagaga ttacggatgt caataaagca tatttggata aaggaaaact atccgtagaa
     8941 cttatgggac gcggatttgc ttggcttgat acaggaacac atgaatcatt gcttgaagca
     9001 tctaccttta tcgaaacaat tgaaaaacgt cagaacttaa aagtggcttg tttggaagaa
     9061 attgcttacc gtatgggcta catcgataag gaacaattgc tggcccttgc acagccattg
     9121 aaaaaaaatc aatacggtca atatttattg aatttggccg ctgaataagg agtccttaca
     9181 gatgaaagta acagatacaa aattaacaga tgtcaaaatc gtagaaatgg acgtctttgg
     9241 cgatcatcgc ggtttcttca cagaaagtta ttcaaaagca aaatttgcag aacatggatt
     9301 gaaatatgac tttgttcaag acaaccattc actatcagct gaagctggtg tccttcgggg
     9361 gcttcatttc caaaaaggag aagctgcaca gacaaaattg attcgggtag tcactggagc
     9421 agttttagat gtagtagtgg atatccgcaa aggtagcccg acttatggtc aatgggacgg
     9481 atttatctta tctgaacata atcatcgaca gttgcttgta cctaaaggat atgcccatgg
     9541 attcgttact ttgacaccaa atgtgaactt cctttataag tgtgataatt actataatgc
     9601 agaagcagat gggggcatcg catttgatga tccagattta gcgattgatt ggccaattga
     9661 tccatcaaga gcgattatgt cggaaaaaga tcaccgtcat ccgacattaa aagaatttga
     9721 agcagaaaat ccatttgttt acggagaaat ctaagaatta aggagaaatt ttcttatgaa
     9781 aaacatcatt gttaccggag gtgccggatt catcggctct aatttcgttc attacgtggt
     9841 aaacaatcat ccagaagtgc atgtcactgt tttggataaa ctgacttatg caggaaacaa
     9901 agagaacttg gctggacttc ctagcgatcg cgtagaattg gtcgtaggag atgttgcaga
     9961 tgcagaatta gtggaccgtc tagtaaaaga agcggacgca gttgttcatt acgcggcaga
    10021 atcccataac gataattcat taaaagatcc tttcccattt gtacaaacga atatcattgg
    10081 tacgtataca cttttagaag cttgccgcaa gtatgatgta cgctatcatc acgtatctac
    10141 tgacgaggtt tacggcgatc ttccattacg tgaagacctg ccaggacatg gggaaggcga
    10201 aggagaaaaa ttcactgcgg aaacaccata taatccttca agtccatatt cttctacaaa
    10261 agctggttca gatctgttag taaaagcatg ggtgcgttct tttggcttac gtgcaaccat
    10321 ttcaaactgt tcaaacaact atggtcctta tcagcatatt gaaaaattta ttcctcgcca
    10381 agtaacgaat atcttaagcg gtattcgtcc aaaattatat ggcgaaggaa agaatgttcg
    10441 tgactggatc catacgaatg atcattcttc agcagtgtgg ctgattttga cgaaaggcag
    10501 aattggcgaa acctatctga tcggtgcaga cggtgaagaa gataataaga ccgtgatgga
    10561 attgatctta gaaatgatgg gtcaaccaaa agatgcgtac gaccatgtaa acgaccgtgc
    10621 aggacacgac ttgcgttatg caatcgattc gacaaaatta cgggaagagt taggatggaa
    10681 gcctgagttt acgaacttcc gtgatgggtt ggctgacacg atcaaatggt acgaagaaca
    10741 tgaagactgg tggaaaaaag aaaaagaggc cgttgaagca gcatatgcca aaaatggaca
    10801 ataatacaga gaaaatgtca ctgtattaat ggaaaaacac atgtgaggca ggcgctcgcc
    10861 tgtctctttt ttaaaataaa aatcaaggag cggataatca tatgttttta ttaactggag
    10921 gaaatgggca actaggtaca gaattgcgcc atttattaga tgaaaaaaat ctgcaatatg
    10981 tttcaacaga tgcaaaagac ttggatatca cagatgccga gaaaacaatg gcttacatca
    11041 cagaattaaa acctgatgtt attttccatt gtgcagctta cacagcagta gataaagcag
    11101 aagaagaagc aaaagaatta gatgagaaga tcaatgttga tggtacaaga aatgtagcac
    11161 ttgcagcaaa agctgtgaat gctcaattcg tctatatcag tacagactat gttttcgatg
    11221 gaaaaaacaa aaatgtagaa tacgaagtag acgaccaaac gaatccacta aatgaatatg
    11281 gtcgtacgaa attattaggc gaaaaagcag tagaagagat tttagaagac tattatatca
    11341 tacgaacttc ttgggttttc gggatctatg gacacaattt cgtcttcacg atgcaacgcc
    11401 tagcggaaac ccgcgacaaa ctgactgtag taaatgacca gtttgggcga ccaacttgga
    11461 cacgtacttt ggcagaattt atggtatatg tcatcgaaga aaaagcacca tttggtattt
    11521 atcatttgtc gaacgaaaat agctgttctt ggtatgaatt cgcaaaagaa atattgaaag
    11581 atacagatgt agaagttgca cctgttacgt cagaagaatt tccgcaaaaa gcaacacgtc
    11641 cgcagtattc agtcatgagc ctgaaaaaga cagaagagtt aggatttgtc ataccaactt
    11701 ggcaagaagc acttgcgcaa atgctggaag ctgccaaaaa aatgaataag taatttcctt
    11761 ttattaaata gaatttggag catgatatgg aaaaacaaac aagaagtgca cgacgaaaag
    11821 aaaagccaaa agcgaaccag gcagattcga atttggtgct tgacctgttt ctaaaactcc
    11881 gctatcttat tggcgtttta gtcatcgtgg tcatcgttac ttttaattta aacggaagtt
    11941 cacttggtgt ttgggataaa tatgtgtcgc aaagagacga tgggaaaaaa actgatgtga
    12001 tttttggaca gaatcgggaa gtgcggtcag acgaatggct ggtgcagaca cctttttacc
    12061 tctcacaagc tgaagaggac tttccgttgg tgaacgagga ttattcatta aacggacaaa
    12121 acatgatcat tgcgtataat tctcctgtaa aggatattac ggttatcgga aaaccattca
    12181 actggggatt ctttttcctc ggaagagatc gaggactttc cttttattgg gcgatgaaat
    12241 tagtcgtcat ggtcttgctt ggattcgaag tactgatgat attaacgaag agaaaaaaag
    12301 ctctatcgct aatcggtgca tttgcgctga cattttctcc agcagtccag tggtggttca
    12361 tgcaacatgt gggcgatttg attttcttta ctttgggact gatgactgct ttttatcatt
    12421 atttctacaa tcatgataaa aaatggctac gaacgttgat gatgcttttg gtggttattt
    12481 tcggtattgg gtttatttta gtgatttacc cagcccatca agtgatgctg gcgtacttgc
    12541 tgatttttta ttttgttggc ctgcttattt actatagcaa gaaagtttca tgggatctgt
    12601 tggatgtagt gttgattgga ggggcagttt tatttattgg cggagtcatg gttcatttct
    12661 ggctaacgtc aaaagacgca ttgttagctt ctttgaatac cttatatcca ggaaaacggg
    12721 taagtactgg aggaaagtgg acgattggcg aatttttttc tttccttaca aattggaaaa
    12781 ttccttttga agatatcaac tattcgaata actctgaagt ggccctgttc tatcactttt
    12841 ttccaactgt attcctagca agtccatttg tgttatttgg caaaaaagat agcgaacaaa
    12901 agttactggg acgtattttg atgatttttt gtctgttttc tatcttttgg attaccgttg
    12961 ggttgccaaa atggctagca gaaatcactc tgctgtctta tgttcctcca ttaagagcca
    13021 tccttacttt tagttttgcg gcttgtttat tatcgatctg gtttatcgct tatatttgga
    13081 gagaagatgt tattcctatt tggtataaat tcattttgtt ggcagtaaat gcatggtctt
    13141 atttctatgc gattacgcat tcgaaaatgg ataattattt ttcggatttt gaaaccatcg
    13201 cagttgctgt gttgggaaca gtgattttag cttttgcatt atttggctgg agacgcttgt
    13261 tttacatcgc ttttgccgcc ttagttatcg tatctggctt tttcgtcaat ccagtcgtag
    13321 aaggtacagg agcgattttt gaaaaaacac tggcaaaaga aatccaaaaa atcgatcaac
    13381 aagatcctgg taaagtttgg ttgtctgaag atgaattata taacttcacc ccaacattgg
    13441 gagtgaaatc cttcaataca gtacgctttt atccagatat agctgcatgg aagaaaatcg
    13501 atccgaaaga agaatacgag aagtattata atcggtatgc tcatacaaga gcttttatcg
    13561 ctaaggaaga tacaaagttc attttagatc gtccagatat gttttcggtc acgttgaatt
    13621 ttgaagacgc agaaaaatta gggatcgact atgtgatcag taaacgacca ttaactgatt
    13681 acaaccaatt atatgaagcg cagttcacgc agctatatgg accggataaa gacggttata
    13741 tgatttttaa agtagaatat ccggattatc cagatgtacc acaaacacaa actcaggaaa
    13801 atcagctagt cgtacagtaa taggctagct gagaataatc ctgaaatgtt agtagaaagg
    13861 agagtggaga taattcaagc aatcgtacaa aaatttgtca acaaaatgag tgtcggtttc
    13921 ttgcttttgt tactgacgct agtctttttt gtttggacag cagggttagg ttttccagca
    13981 actttgttta tatataacaa tagttcatta cttatcgctt ttagtgtggc tattttgctc
    14041 attttaaatg tttataaagc aaaaggcgtc gattttcttt atctaggtgt tgcgcttgcc
    14101 cttttcattt tcttttctta ctttcgggaa ttaagaaatg agtctttatt tggagactta
    14161 ctgtttcctt tgattatttt attttgttta gtaattaaat ggatcgagtg gacaaaatgg
    14221 gatcgcggta tttatctgat tgtcttttcg gtcttcctcg gaatcacgtt tatcgtgtat
    14281 ttacagagat ccaagtacca gaaggacaaa gcatctgggc tccaggcaat tcgctttctg
    14341 atatttggat caatacgaat acaatcggaa gttctttgat gactcttgct ttattgatca
    14401 gtggatttgc cagttctttt gaacgatggt atgtacgaat catcggtgca gtagcagttg
    14461 ttgcagcttt tctcgggatt tgggtctgcc aatctagagg tgcattagtc gcgttgattg
    14521 tttttgcgat attggatctt ttacctaaat cgttgatgcg tgtcattcgt gcgccattta
    14581 ttgcttacac ggttacgatt cttttagctt tgccgatttc ttatctggcg gctgtctctg
    14641 aaaaagtcaa tttgtttacc ggtcgagaag atatttggca taaattctat cagacgctag
    14701 gagaaaaatc tgaacaaatt ttactaggaa tgaaaacatt tatcttccaa cgaggaaacc
    14761 aatttttagg aaaccacaat agttataatt ctattttgaa tatctatgga ttgataggat
    14821 ttgggattgc tgctttgctg cttatccttt ttattggtcg cttaacgttg aaagcagatt
    14881 tatccaacgg gcagatgact tttatctggg ccttttttgc ggtgatgatg cagtcattta
    14941 tggaggatac attgacttca taaccatggg ttccgattat ttatatcctg ttggctatgg
    15001 ccgttcatcg atatgatgaa ccagaagttg cggaggaatt ctatgttatg gaagaggcat
    15061 atgacgatat gacttatgat gatacatctt atgaggaaca accagatagc gctcattctt
    15121 ccaggatcca acgctatcat tgataggcac aaaatacgag agaggctgtg acaaccgtcg
    15181 cagccttttt tggtttattg caattgtcta gcatcttctg taaaatagaa acgttagaga
    15241 aaatcttgta tcatagaaaa ttaagaaaga aataagaacg cagctcggta ccaaaaatat
    15301 ggtaaaatgg cacttgactg taattcactg aaaatcgctt ggaggaacac aaatgtttaa
    15361 agatttgtat ttatttatga aggacattta tcagaacaga aaattattgc tacagttttc
    15421 gatcaatgac ttcaaatcaa gatatgcagg atcgttttta ggaatcttat gggcgtttat
    15481 caatccgcta tttactgtat tgatttattg gctggtattt ggtgttggac tgaaagcaca
    15541 aatgatcgat gcaaaatacc catttatcgt atatttagtt accgggatga ttccctggtt
    15601 cttcttctca gatgcatttg catcaactac ggttgttttt cgggaatata cttatttagt
    15661 aaagaaagtc gtattcaata ttcgtatctt gcccacgacg aaaatcctat ccaatctgta
    15721 cacccattta ttcttcattc tgattggcat agctgtcgcg cttataaatg gtatatatcc
    15781 ttcagcaatg tctttacagc tgatttatta tttattttgc atgtgtgctt tcttgacagg
    15841 attgacttgg ctgacggcat cgatccaacc atttttacct gatatcatgc aattaattac
    15901 gatcgtgctg cagttgatca tgtggacatt accgatatta tggagcccta atcagtttga
    15961 ttcaggtctt gtaagcatat tgaaattaaa tccgctgtac tatgttgttc aaggttatcg
    16021 tgagtcattt ttaagtgaag cttggttctg ggagcatgga acatatactt tgtatttctg
    16081 ggttttcacg ttagtaatgt tcgtaatcgg ctctgcagtg ttccgtagat tgaaaccaca
    16141 tttttcagat gtgctgtaag gagaatagct atgacagaat atgcaattag actaaaagat
    16201 atcacaaaat cttataatat gtacgcaaaa ccttcggatc gatttcgtga agccctcaat
    16261 ccttttaaga aatcctatca tgatgtattt tatgcgttga aaaacgtgaa tgtagaaata
    16321 aaaaaaggtg agatgatcgg tttcgtggga gaaaacggat cgggaaaatc tacaatgttg
    16381 aaaatcatta cgggagtact gacaccaaca tccggcacga tggaaatcga aggaaaaatc
    16441 tcagctttgc tagaactagg atcaggattc aatcctgagt attctggcta tgaaaatatc
    16501 tatttaaatg gaatggttct aggattttca agagaagaag tcgatgaaat ggtcgatgat
    16561 atcattgaat ttgctgacat cggagaccat atttatcaac ctgtaaaaac ttattcaagc
    16621 gggatgttcg ttcgtctagc ttttgctgta gcaatcaatg tgaatcccga tattttgatt
    16681 gtggatgaag cattggcagt aggcgatctt gaatttcaac taaaatgtat ggaaaaattt
    16741 acagaaatca agaactcggg aaagacgatt ttattcgttt ctcatgatat cagttcgatt
    16801 cgtcgttttt gtgatcgttc ctattggttg aaaaacggag aagtcgtcga atatggcgat
    16861 acgatggaag taacgacgaa ttatgaaaac tttttaaaga aaaaatcagt taaaacagtg
    16921 gatcggaata aaaaccaagt agaacggttc gccgctccag atatcgtcga cgtgacgaaa
    16981 gcggaattgt tggataaaga caaaaatccg gtggatatgc tggaacaagg agaaaaacta
    17041 tacgttaaag taacttatga agtaaaagat gatacaatca aaaatccggt tttaggaatt
    17101 gcgctacgaa cagtcgacaa tttttatgta tgcggactta atactctact agatggtatc
    17161 aagattcctt ggaaaaaagg agagaatatc ttttatctgg agtatgaaaa gttaggtttg
    17221 ttagctggtg aatattattt tgacgttgcg gtctttgaag aaaatgcaac ggttcctttg
    17281 gtatataaga caaagtacat gaacttgttt gtcagcggtt cttatatcgg agaaggcatc
    17341 gtggtcttag accataaatg ggaagaaggg actcatagca atgaaatatg attttgaaat
    17401 ggacctagat gaacaaagca gtgtgggaaa aattgccgca cagatcaaac caggaagtaa
    17461 agttttagag tttggtcccg gaaacggccg attaacgaaa catttaatcg gagcaaaaca
    17521 atgtgaagtg agcattgttg agttagataa ggaattgttc gattttgtca gcgaatttgc
    17581 tcaagatgga ttttatggtg atatcgaaag ttttgagtgg gcaaactatt atgctggaca
    17641 gacatttgat tacgtcttgt ttgcggatgt tttagaacat ttggtagatc ctggaaaaac
    17701 attgaagaaa gtcagagaat ttttgaatga agaaggagag atcctgatta cattccctaa
    17761 cttggcgcat aattctgtca tgatcgattt gttcaataac caattgccgt gggcttctta
    17821 tggtctccta gatgaaaccc ataattcttt ttatactcat gatggcttcc aaaaagtttt
    17881 tgaaaaagcg ggattattca ttaatattga agattatttg tacttagctg taggtgatac
    17941 agaattaaaa tcaacttatg aagaattgcc ggaagctgta cgctatgatt tcaaaatgcg
    18001 accatttggt gaagtctacc aatacttttt ctcattgatg aaacatccag tagcacaaag
    18061 ttccattgca gagccacaaa attctaatta tgtaaaagtg ttagaagtaa cccagcaaac
    18121 gaaacaagat gaaacaatcc aacaaatacc attcaataat ttcacagggg aaaatgagac
    18181 actaagtttc cccgtatcag aaacaacaga aagaatggtg tttcgcttcg cgcaacaacc
    18241 tagctttatc gaattcagcg cagaagctgc cggagaaaaa ctaacattta tcgattcgaa
    18301 tgctgtagtc aaaacagtaa atgattgtta tttgtttgat gggaaagaat taccagagtt
    18361 cgttctaacg gatatttctg ggaaagaagt gactatccat tgtcactatc gctttatcgg
    18421 ggaattgaca ccaacaatga aagaattgtt ggaaacgatt cgtcccatgg ctgaagtcac
    18481 aaagcagctt tctgagaaaa atgacgaatt agaaagagaa aatcatcatc ttcttgagga
    18541 aaatacaaga ctagaccata cgttaaaaac aaccacaaat cgctattgca cattgttgga
    18601 aagtgatgaa tggacaataa aacatagact aggacgacgt aagaaagaaa cttcgaaaaa
    18661 aatccaagaa aaagaacttt ctatatgtat tgacgagaaa atctgggatg cagaaacaaa
    18721 aatattaaaa atcatcggat ggggaatcgc taattcggat cgccagccct tgtcctataa
    18781 gttatcagct gaccaatcgc catttttcga agcaattcct gtttcacgag aagaagtcaa
    18841 tcaagcagaa cagctcgcaa aaggaacaga agcgggattt gagttacgaa tcctttgcga
    18901 gcaagaacgt tcattcttag tggaagcagt agctcaaaat ggccaatcat ggatcattga
    18961 aatgtaaata atgattaact tataaagata aggagtaaac gaatcgtgca aaaaaaagaa
    19021 attgccgtat ttatcgatca aatcactcgt gaacgggcca ctggcgattt gcttattgtg
    19081 ggctgggcaa ttgatgaagt gaccaaagaa atccctacga taaaggtaga aaaagaaaat
    19141 gtgattgctg aagcaacaca tgtcgtaaga ttggatatca atcatttata taatcttgat
    19201 gttaagaccc aaagcggttt taaggtacgt ttatcaggga aaatgagagg aaaagccatc
    19261 ttagacttcc aaacagcgag acatcaaaat ggcatagctg tgaaattaaa cggtaaatac
    19321 ccttatgatg acggcattga atcttcatgg gaaagaaaaa aaagattact gaaaaaaggg
    19381 ataaattatg caaggactca tggcgtaaaa aaagcgatcc gtcgggtcaa attggaattg
    19441 aagccaggat cgatcgacta tgcagagtgg atcagtcgtc atgagaaacc agatttgaaa
    19501 gagcaaagga aagaagcaca aggatttgcg taccgtccat tgatttccat acttatgcct
    19561 gtctataacg ttgaaatcaa atggctcgaa aaatgcattg attcggtact ggatcaaacg
    19621 tatgatcatt gggaactatg tatcagtgat gatgcttcta ctgatccagc tatccgaaag
    19681 tgtctggaat cctatcaagc aaaagatgat agaatcaaag tcgttttccg aaaagaaaat
    19741 ggacacatca gtctggcaac taattctgca ttggaaatag cagaaggaga atttatagca
    19801 ctcttagata atgatgatga attaccgcca tttgcattat atgaagtggc aaaagtgcta
    19861 aacgtacatc cagaactgga tgtgatctac agtgacgaag ataaaatcga tgcagatggc
    19921 aatcgctttg atccgcattt caaagcagac tggtcgcctg atacattgat gggaaataat
    19981 tatatctctc acttaggcgt atatcgaaca agcattgtta aagaacttgg cggtttccgt
    20041 aaaggctatg aaggttctca agattatgat ttggtccttc gtgtgacaga acaaatccct
    20101 gcagatcata tttaccacat tgaccgagtc ttgtatcatt ggcggacgat cccaggatca
    20161 actgcaagta atggcgaagc caaaagttat atctatgatt ccggagtgaa agcattgaca
    20221 gatgccctgt ctagaagaaa catcaaagga agcgtacgtc ctggcagaat ttctggattt
    20281 tatgagattg cttatgacgt cttgcaagag gatttggtca gtgtgatcat tccaacgaag
    20341 aatggctatg aagatctaaa aacttgtgtg gattcgatca tcgaaaaaac gtcttattca
    20401 aattatgaaa tcattattgc ggataacgga agtacagatc caaaaatgca agaattattt
    20461 gcagaataca agcatcagct gaaagaccgc tttatcgtag aattgattga cattccattc
    20521 aattattctc gaattaacaa tttagcagca gaaaaagcaa acggcaaata ctttttattc
    20581 ttgaataacg atacagaagt gattgagcca gattggatga cggtgatggt ttcttatgca
    20641 cagtttgatc gaatcggctg tgtaggagca aaactgtttt atccagatga tacaacgcag
    20701 catgcaggag tattattagg aatcggtggt gttgcagggc atgcattgaa taactatgat
    20761 cgaacacatt gtggttattt cggccgattg gtcattgacg tcaattactt agcagtcact
    20821 gcagcttgta tgatggtcaa ggcagctgac ttcaatgctg ttaacgggtt tgatgaaaca
    20881 ttagaagtag cattcaacga tgttgacttg tgcttgaaag tttatgaact gggtcgttac
    20941 aatgtctatg cacatcaagc agaattgtac catttcgaat ctaaatcaag aggttatgaa
    21001 gatactccag aaaaacaaag acgttttgct ggtgaaatca aaaaaatgca agataaatgg
    21061 ccagcatata ttgcgcatga tccattttac aatgataatt taacaaaaga aggaatcggc
    21121 gacttttcgt tgagaccaga ttaaactata ataaaaagct gttatgttgt gattcgctcg
    21181 cacataacgg ctttttatag ttttttgtca aaaaaaggca gaaggtgccg actcaaaaaa
    21241 ataagtcgag gttgggacag aagtgtttaa ctccgagaaa taagaagaaa ttcacgaaaa
    21301 ttgcttttca aatttttgtg aatttcggct tatttaagaa gaagttgctt ctgctcccac
    21361 cgtttattcg tttttaaaga atgagacaaa agtgtttctt acttttgtcc cacgctctta
    21421 ttcatgctca gagcgccaat agatacaaaa tcatagccaa agtttcacga accctagctg
    21481 tcaaagaatc gatattttat tttaatatag gctattttaa aataaatggt ttaaggtatt
    21541 cctctacaaa agccactcta tcaattatca tgggtttaaa ataagaagtg atggagataa
    21601 ccagattgtt cttagcgtca atataaagaa catttccact attaccaatt gctgaatata
    21661 tttcgttctc agaatctaat acccaccata aatagccata tctcatattt tgtaagtctt
    21721 ctaaagcact ggttctaggt ttgaacatct cgtttatcca catgggtggt acgatttgtt
    21781 ttcctttata catcccttta tttaggcata atacaccaat ttttgccaga tcacttgccg
    21841 ataaacacaa accatatcct gccgtcccga tatttagtgg atcacaaaac cagacattgg
    21901 ttttaggaga cttatccatt gtaaactgct tatgttcttc agctgtttca gcataataat
    21961 tgacatggtt tggtatccct ataggatcaa atagatactt attggcaaaa tcaacagttg
    22021 ttagcttact tgtctgatac aacaagccag ttaatatgtg taaacagaca gtttgatagt
    22081 tgaattcgcc ggttatacct tttcttcctc ccaataaatc tagtgatgtt tttgtccaat
    22141 cttcacttga acagactttt gtccatggat cgcctttaca tttgtagggt gctttcattg
    22201 ttagcaagtg cttgattgta atagcgtaaa tagttttctc cccgcgtttc actttatact
    22261 ctggaaaata atctaatact ttatcatcga tacttttgat taatccttgc tctaaagcaa
    22321 tgccaatcag caaagataca atacttttcg ttgctgacat gatatgacaa gtatcgtctt
    22381 ttttataacc attccattca tctgtataaa cttctacccc atccttatat gcgacaattt
    22441 gacatatatt tggttgtcga aaaccaataa aatcatgcaa ctcttgttta ttcataagat
    22501 attacctcac tttcttctat aagcataatg tcattaaaaa tcgatttcaa ttttttcgat
    22561 tcttcacgta atacaggtat tcttatggac tagacagcgc tttgggaaga tggattctct
    22621 gaaaaatata aaggttcact ttatgagtgg ataaaaaaag cagcaaatac ttcgacttct
    22681 ttaatttacc aacattagtg aaaatcgatt catctggaga tttgtaattt agagtccttg
    22741 tcttgattag aggtgtataa agctttttat tagacatttt taaattccat tacaatttgc
    22801 ttataaacta ggtttttaaa ggtgactatg gtaagataat agagatatta ttttgt
//
LOCUS       DAFBSV010000045        22357 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.046, whole genome shotgun sequence.
ACCESSION   DAFBSV010000045 DAFBSV010000000
VERSION     DAFBSV010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22357
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.046"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(<1..901)
                     /locus_tag="LLB18_001591"
     CDS             complement(<1..901)
                     /locus_tag="LLB18_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBK5244596.1"
                     /translation="MRVRETTRRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     QKIFYSGLAYLPLNYVVTRIPEAFHRFEIIPGSLQGVNIFQLQEMPQLFHFDSTGFWN
                     PLTPTTSLGTRLVVSTICVVPAVLMGLKMDMWFRPLADGQKGDNRLKTLKEIQQIYPQ
                     IPESKGGFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     RQSSMVVNDPKTELYVASKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNK"
     gene            complement(901..2964)
                     /locus_tag="LLB18_001592"
     CDS             complement(901..2964)
                     /locus_tag="LLB18_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244597.1"
                     /translation="MFFTISGNAKLDKELIRKATKKVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQVSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMDQLEVDPFEETMEDEETAEVEVDPVEA
                     NEESTWTEGDSQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKVKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVE
                     KINNFTKTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKHEQIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLEIRKREQD
                     LAEQKMAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPTPSVAAVQTPM
                     NNQTNLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTTSIKEE
                     AQEQARKEYEQQLEELLNRTNQSTTESSMENSKESDPSKAKEGSSDSTVQSNTSESSE
                     SNEVK"
     gene            complement(3033..3335)
                     /locus_tag="LLB18_001593"
     CDS             complement(3033..3335)
                     /locus_tag="LLB18_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244598.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAGVAA
                     VASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGIILAAASIVVSLFGMFGQTPQGL"
     gene            complement(3353..3595)
                     /locus_tag="LLB18_001594"
     CDS             complement(3353..3595)
                     /locus_tag="LLB18_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HBK5244599.1"
                     /translation="MIASLFIYPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            complement(3592..4047)
                     /locus_tag="LLB18_001595"
     CDS             complement(3592..4047)
                     /locus_tag="LLB18_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244600.1"
                     /translation="MKKLIMVFTSLIAMIVILGGCGSEKNKQDSQDNGVLKPGTVWKE
                     EVGGLVHNLKIIDDTTWEYSESVWHPEQVQITVEKLKDYKGLERYKVIDSGGVDLFIG
                     KTALIVPYNKDGLETFKFIPTNEKEHRDKSEILKEYSTKSGYKLQKTSE"
     gene            4235..4426
                     /locus_tag="LLB18_001596"
     CDS             4235..4426
                     /locus_tag="LLB18_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244601.1"
                     /translation="MYADKEKIEWLLFETGKTAYEISKHSSVAESTIADLIKKKSAIE
                     KMRFDNAAKLTKYAESISS"
     gene            4570..6627
                     /locus_tag="LLB18_001597"
     CDS             4570..6627
                     /locus_tag="LLB18_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HBK5244602.1"
                     /translation="MKLLNPKTVIAIGTFAATVALAGSADAASTNVMYRLYNPNNHEH
                     FYTSSTKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVTSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNTLDSAYKGLKKKPAPTVNKTELQALYNQVKSTAKGDFTEGSWNNFQTAL
                     SNAKKVLDDSKASQTQVNNAKNSLDSAFKGLQHKPKPSEYAVTVRHMNRQTGTLLKEE
                     HVSVKAGTSYTAKARTDLTNFEAPQYQVNGNETQTQTINTNTTFTFYYDEVFLVEVKA
                     RPNKVSDTDPNIQELYNYSKSYPVVYGQSITIEAPMFTNFVLDPRESSSNTVTLNNVT
                     SNQGINFAYTHQYNVTVNHINVDTNAVLSTETQTVYEGDSFSTSWKNMTDQNYFLCRN
                     DDSSVTVDKNGQRVINNVDQNRTITFKYKNISLSDLNNYVRQKELAWLNSYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENINSFYLYVD
                     EILSDTGAVNAMVMWKDSAAHNANLLYNNQSIVGLSHAYEVSADGSLSSDNVFISANP
                     IFK"
     gene            complement(6663..8753)
                     /locus_tag="LLB18_001598"
     CDS             complement(6663..8753)
                     /locus_tag="LLB18_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBK5244603.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRQDAVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVDYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YNDGSAQVIDKSTGKDITSEGTLTYDSNSRTLKWEASADFLNNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTILAVSLLL
                     LVLATFGYAVLKFN"
     gene            complement(8750..9010)
                     /locus_tag="LLB18_001599"
     CDS             complement(8750..9010)
                     /locus_tag="LLB18_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244604.1"
                     /translation="MKLIKLLLFNLSCLTAVFLYCGLLFSQLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            complement(9023..9778)
                     /locus_tag="LLB18_001600"
     CDS             complement(9023..9778)
                     /locus_tag="LLB18_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244605.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADSQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGHEKQEGVNG
                     AKFSVYDVSDILQKMDVKDLTTDQIESQLKDRVKKLSSDQLKLVSNGETKTIDQQTGV
                     FEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSEKNGEFLKDVWIYPKSEAS
                     QPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            complement(9794..10546)
                     /locus_tag="LLB18_001601"
     CDS             complement(9794..10546)
                     /locus_tag="LLB18_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBK5244606.1"
                     /translation="MIIRHPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVSKIELGDPVGILTIPSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLEPNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            complement(10559..12535)
                     /locus_tag="LLB18_001602"
     CDS             complement(10559..12535)
                     /locus_tag="LLB18_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBK5244607.1"
                     /translation="MAINRYVKKAGMLVGMLGIIASCFQGYQAHAEDVTQKTPPEKVN
                     ITVHKLMYDQSTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PTEDSDLTNAKVDEIVKDVEDKGSNSEYVKNATNKITSAVDENGEITFADQPAYVNSK
                     GNVYVIYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELTK
                     FGDDGTEQSKQTPLKGAKFELYKGEPGKGSKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDKEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQVGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLTDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGDYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQSYVLISCLLLGAGAISAVVYFKKKA"
     gene            complement(12587..13258)
                     /locus_tag="LLB18_001603"
     CDS             complement(12587..13258)
                     /locus_tag="LLB18_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBK5244608.1"
                     /translation="MKKWLFGFLGVALIVVCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPGYFRLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            complement(13340..14506)
                     /locus_tag="LLB18_001604"
     CDS             complement(13340..14506)
                     /locus_tag="LLB18_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HBK5244609.1"
                     /translation="MSHIQELVEKLINKMSAIFLLLLVSILYLIWTVGLNPPTILFIY
                     DNAAQLVTFFVGCLFLLNLYKVKRNDLFFIAAGILFYLFFSFFRSYRGDTFYGDLIVP
                     TIIAIILIVKWTEFTVFDRSLYLVVFYVFLLVTVYRVFTEIPVPEGQSIWNPSNKLSD
                     IWINTNTIGSSLMTLALLITGFASSFGKWYMRLLSLPALILAGATIWVCQSKAALYAL
                     VIFVILEILPKKIFRNTHLSFWMYAAVSVLALPISYFAAMSDKVHLFTGREEIWRKFY
                     ETLGEKTGQIFVGMKPFFFHRGNQILGNHNTYHALVNHYGLIGFALSMILLLSFLWLL
                     VRKCELTNGQLTFLWAFLAIMCQSFMEETLATISWVPIVFLMLAMATHQYKTTR"
     gene            complement(14512..15201)
                     /locus_tag="LLB18_001605"
     CDS             complement(14512..15201)
                     /locus_tag="LLB18_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HBK5244610.1"
                     /translation="MNKNNKTLFNPYVGVIIVFLLFSYFAYQGYQKDKIAEKVDDVTK
                     TIHIQEQAKTYQDNLTSLTDISKRQLITNQKQALEKDLKGEIAGKLVFSSTGFILPVF
                     QGANSDTLSLGVASTYYPDAEMGNGNYILAGYNVDTPSVLLSDMIDLSEGEEIDLIDA
                     HYKYQYEVSKRGKIYDYSQVVQSKENNSFLSLPKAGKKPLLTLLDFEANNMKKCDVIQ
                     CELVNVEKINK"
     gene            complement(15328..15567)
                     /locus_tag="LLB18_001606"
     CDS             complement(15328..15567)
                     /locus_tag="LLB18_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244611.1"
                     /translation="MNCKESVNWKKVSKEMEEKLLKMMKQKHLKRLSVMQYINDMQIT
                     GKEKACLLGSMKNFEQLRRTYVKTSSNCQLLLEVS"
     gene            complement(15634..15873)
                     /locus_tag="LLB18_001607"
     CDS             complement(15634..15873)
                     /locus_tag="LLB18_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244612.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKALSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            complement(15987..16328)
                     /locus_tag="LLB18_001608"
     CDS             complement(15987..16328)
                     /locus_tag="LLB18_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HBK5244613.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYYQKLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            complement(16947..17279)
                     /locus_tag="LLB18_001609"
     CDS             complement(16947..17279)
                     /locus_tag="LLB18_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HBK5244614.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYAGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            complement(18126..19166)
                     /locus_tag="LLB18_001610"
     CDS             complement(18126..19166)
                     /locus_tag="LLB18_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBK5244615.1"
                     /translation="MTDFNFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCSVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFIPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAETESGISIIFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNSE
                     SFPKTITKDWLE"
     gene            20332..20418
                     /locus_tag="LLB18_001611"
                     /pseudo
     CDS             20332..20418
                     /locus_tag="LLB18_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            20978..21196
                     /locus_tag="LLB18_001612"
                     /pseudo
     CDS             20978..21196
                     /locus_tag="LLB18_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            21456..21710
                     /locus_tag="LLB18_001613"
     CDS             21456..21710
                     /locus_tag="LLB18_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBK5244616.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDTIQAKQEGNLIILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            21711..22028
                     /locus_tag="LLB18_001614"
     CDS             21711..22028
                     /locus_tag="LLB18_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBK5244617.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
BASE COUNT         6743 a         4276 c         3497 g         7841 t
ORIGIN      
        1 atttattgtc tgaagcgttg gcatcataat aaatcgtatt cgtgaaagta ttggttaact
       61 gtgtcgctgt gtctatgtct cctcgcttcc agtatttcac gatgagtgcc aatggattat
      121 cactcattga ttgcagtgga tcggtgatat taaatgcata cacatcatac cctctagctt
      181 ctagttcatc tttactagca acatataatt ctgtttttgg atcattaaca accattgaac
      241 tttgtctttc tgcacgagac aaattgtcaa tggttgctaa aacttctatc tgtcctttcc
      301 ctgaacggga agtaccaaca atacaagtat ttactgtatc cgtctgaata taccagtact
      361 ttttataatg agtaattggt attccgccat aaccaggaaa acctcccttt gattctggta
      421 tttgcggata aatttgttgg atttccttta acgtttttaa tcggttatct cctttttgcc
      481 catctgctag aggacgaaac cacatgtcca ttttcaatcc cataagtaca gctggaacaa
      541 cacaaatcgt agaaacaact aaacgtgtgc ctaaacttgt tgttggggtc aaaggattcc
      601 aaaaaccagt tgaatcaaaa tggaataact gcggcatttc ttgtaactga aaaatattca
      661 ctccttgtaa acttcctgga ataatctcaa atcgatgaaa tgcttctggt attcttgtaa
      721 caacatagtt taaaggaaga taagctaagc cactataaaa aatcttttga gaaatacgtt
      781 tgtcatgttt ttctggtagc tcttctcctg aaggagtata gcgatagaaa tgagaaagat
      841 acctattctt ttctaaattg aatcgtttgt cttttcgtct cgttgtttct ctaacacgca
      901 ttatttcacc tcatttgatt ctgaactttc ggaagtgttt gattgtacag ttgaatcgct
      961 tgatccttct ttagccttac taggatcact ctctttgcta ttttccatac ttgattctgt
     1021 tgttgactga ttggtacgat tcaataattc ttctaattgt tgttcatact cttttcttgc
     1081 ttgttcttgg gcttcttcct tgattgacgt cgttgtggcc acagaatcag cctgtgaaga
     1141 ttgattgata tgattaaaag caaatactgt tcctccacct agaagcaagc ttaaacttgc
     1201 aatacatccc accatccatc cgttaaagga acgctgtggt gaaggagtta gatttgtttg
     1261 gttgttcatt ggggtttgaa cagcagctac tgaaggcgtt ggttgaggtt gtgctagata
     1321 atttaactga gcttgtcgca atgtatccat ttgttcttga cgttccttac gagcagctgc
     1381 ttctttttcc ttttcttgct ctaaccgttg tttttctatc gccatttttt gttccgcaag
     1441 atcctgttcc cgttttctta tttctaattg ttcacgctct ttttcttttt gccgttgttt
     1501 ttcttcttgt tctttcaatt cttgttgttg aatttcatac tcttttttcc attttggaat
     1561 ttgtacttgt aattcttgct ggatctgttc gtgtttttcc ataagaactt cagtcgttgt
     1621 ttgatatagc ttattcagtt gttcatttaa ttctttgcta atctttagct tatctgtacg
     1681 taaaccgcgg tagaactctt cttttcgttc tttaatacgt tcttttaaca agttttcttt
     1741 ttctttcgat aacgcttctt gattcgtctt agtaaaatta ttgatctttt ctacacacaa
     1801 ggaataagca ttgtcgcgtt tcttttcgta ccgctctttg attttttgta cttcttcttc
     1861 aatcactcgc tgttcttctt tatttagttc ctcttttact ttctcccaat tagacgactg
     1921 ttccgtcgca tactcattaa tttcttgatc tgtttcttgt tgacgttctt caaaggtggc
     1981 taataaatct tcttgtgcaa gctcatgcca atttgttgat tggacagact ctaactgttc
     2041 taaaagtgtg cctttaccct gtgagattaa ttcttcttta ctctctaaaa atgcttgata
     2101 ggtttggggt aattgatatt tcgaataaag ctcatttaaa aataatttgt ttttttcttt
     2161 catccattca tgctctggcg gatattgatc caaaatataa tcaaatacag ttgccttttg
     2221 tatctctgtt tcgttttttt ctacttcttc actgataagt ggttcaatat attcctgaga
     2281 atccccttca gtccatgttg actcttcatt agcttcaact ggatcaactt ctacttcggc
     2341 cgtctcttca tcctccattg tttcttcaaa gggatctacc tccaattgat ccatcacatc
     2401 gttctcttcc tcaaatatcg atttctgagt cggaatatca gcttgttcgt caacatagac
     2461 tgtctctttt tcttttgact ccttctttgg aaatattggt cgttcccatg gtacttcttc
     2521 atttacttcg acttcactca cttgattcac ttttctttgg tcgctctcta actcttcttc
     2581 taaaacttgt aaaagttttt cgtttcgata agactcttcc acactcatag tttcatccgt
     2641 ttctttaaac acatcaaggc ggattaaatc catcaatgta ggataaaaac cttctgaaat
     2701 ttgataatcc agtgggccaa aaacgtattc tgtgccagcc ttttctattt ttccttcttt
     2761 atcatgtaac gtgagagtca atttaacaga agattgattc tcttgttcta acacttgtcc
     2821 taacacatgt agctgttctt ccgtttcaat gacagaatat ttaattgttt tcggtaaaaa
     2881 ggaagtacgc tttcccactt tcttcgttgc ttttcttatt aactctttat ccaattttgc
     2941 attgcctgaa atcgtaaaaa acatgaatat tctcctttca taaaaaaagg agtaaaaagt
     3001 agctatgtac tttttactcc ttcattttgt ttttataatc cctgtggggt ttgtccaaac
     3061 attccaaata acgaaaccac aatagaagcg gcagctaaaa taattcctac ccccatcaat
     3121 acatatccca catgcatctt cccgttttca gcacctcttc gtccaaataa gaagaaaagc
     3181 cccccaataa caatggaagc aacggccgca acgccggcaa aaatcattaa attgtttttt
     3241 aagctagttg ctgcagtttg taatgctcta aaaatatcaa ccgcagctac tactttcggt
     3301 tgtgttaaaa aattcattgt aattgattca aacataaaat tgttcgctcc ttttagtgtt
     3361 taataatttc atcgaaaaca agcttttcac gttcacgttg atagatatat ccttctaagt
     3421 ccttgtcttt tccccgtaat aggtcaaatt gtgctttttc aaggacttct tgtttccact
     3481 gtgtttcaga tacaccgcga cgttctaaga ttttagacgc ggctttttca aatggcgttt
     3541 tagcttttgc cactgtgatt cctccttcag gataaataaa aagactagca atcactcgct
     3601 agtcttttgt aacttgtatc cagatttagt actgtattct tttaatattt cacttttatc
     3661 tcgatgttct ttttcgtttg ttggaataaa tttaaacgtt tctaaaccgt ctttgttata
     3721 gggaactatt aaggctgttt tacctatgaa taaatctact ccacctgaat cgattacctt
     3781 atatctttct aatcctttat agtcttttag cttctcaact gttatttgta cttgttcagg
     3841 atgccaaaca ctttcggaat attcccatgt tgtatcatct ataattttta aattatgaac
     3901 aagtccgcct acttcttctt tccacactgt tcctggtttt aacacgccat tatcttgact
     3961 atcttgctta tttttttcac taccacatcc acctaaaata acaatcatgg caatcaacga
     4021 agtaaatacc attattaact ttttcattct attccttctt tcgttgtttt attttagtat
     4081 atcaaataac gaaagtagca acaaacctca ttttgataca cggggaacgg atactcataa
     4141 tttcccacct ttctatagaa acttttcctc ttgatattgt gatttattac aaaaaagagc
     4201 tataataaag aaaaaatcaa gagggagcat tgcaatgtac gctgataaag agaaaatcga
     4261 atggttacta tttgaaactg gcaagacagc atatgaaatt agcaaacatt cttcagtcgc
     4321 agaatcaaca attgcggatt taataaagaa aaaaagtgcg attgaaaaaa tgcgatttga
     4381 taatgctgcc aaactaacca aatacgccga atccatttct tcatagcata taaacagcca
     4441 tccttacact cttcataggg cggctttttt atttcaaaat ttccacggta taccgttgac
     4501 tacctcggta taccgtggta tattatgaat gtaaacaaaa tatttaatca tttaatagga
     4561 gttgaaaaca tgaaattatt aaacccaaaa actgttatag ctattggaac atttgctgcc
     4621 acagttgctc ttgctggatc tgctgacgct gcttcaacta acgtcatgta tcgcctttat
     4681 aatccaaata accatgaaca tttttacacc tctagcacaa aagaacgtga tcacctagtg
     4741 aaaattaagt ggggtaatta tgaaggcccc gcttgggaag caccgactag cggtggccac
     4801 cttgtctatc gtttatacaa taaaggcctt cgtgatcacc attacacagc tagttgggat
     4861 gaagtgaaat ggttgaccaa aaattacggt tggacttatg aagggcctgc atggcgttct
     4921 gccgaaaaaa ataataaacc gatctaccgc cttttccttc caggtgttac ctctggttcg
     4981 catcactaca ctgcaagttg gaaagaagta caatggttaa ccaaagacta tggctggaaa
     5041 tacgaaggta ttggttggta tggtgctgac acctctaaac ccaaagtgaa taaatcagct
     5101 ttagaagctc tttatacgag cgttaaggga actaaaaaag gtgactatac cgacaatacc
     5161 tggaacgcat tccaaaccgc tttaaacaat gctaaaaaag tgttaaatga ctcaaaagcg
     5221 actcaaaaac aagtggatag tgccaaaaac acattagatt ctgcttacaa gggattaaag
     5281 aaaaaaccag ctcctactgt gaacaaaacg gaattacaag ccttgtacaa ccaagtaaaa
     5341 tcaactgcta aaggagattt tacagaagga tcttggaata attttcagac tgctttatcc
     5401 aatgctaaaa aagtactaga cgattctaaa gcttctcaaa cccaagtaaa taatgctaaa
     5461 aatagtcttg attctgcatt taaagggtta caacacaaac ctaaaccttc agaatatgcg
     5521 gtaactgtcc gtcatatgaa tcgacaaact ggaacgctgc taaaagaaga acatgtctca
     5581 gtaaaagctg gtacaagtta cactgcaaaa gctagaaccg acttgactaa ctttgaagca
     5641 ccacagtatc aagtaaatgg gaatgaaaca caaacacaaa cgattaacac aaataccaca
     5701 tttacttttt actatgatga agtctttcta gttgaagtga aagctcgtcc aaataaagtc
     5761 tcggatactg atccaaatat ccaagaactc tataattaca gtaagagtta tcccgtcgtt
     5821 tatggacaaa gcatcacaat tgaagcacct atgttcacta attttgttct tgatcctaga
     5881 gaaagctcta gcaacactgt gactttaaac aacgttacaa gtaatcaagg aatcaatttt
     5941 gcctatactc atcaatacaa cgtcactgtg aaccatataa acgttgacac aaacgctgtt
     6001 ttatctactg aaacacaaac ggtttacgag ggagatagtt tctctacttc ttggaaaaat
     6061 atgaccgatc aaaactactt cttgtgtaga aatgacgatt catctgttac cgttgataaa
     6121 aatggacaac gtgtaatcaa taatgttgac caaaatcgaa cgatcacttt caaatacaaa
     6181 aatatctcac taagtgattt aaacaactat gtgcgtcaaa aagaacttgc ttggttaaat
     6241 agctaccgtc aacaaaatgg cgttgcccca atgcaattca atgatatcgt tcaacaagct
     6301 gcagatattc gtgcaaaaga attacaagta agcttcagtc attaccgacc tggcggcggt
     6361 actttccaag atctcttaga aagcttaggc tgctacggtg ctaaaggaga aaatatcaat
     6421 agtttctacc tttacgttga cgagatcctt tcagatacag gagcagtaaa tgctatggtt
     6481 atgtggaaag atagcgctgc tcataacgca aacttgcttt acaacaatca aagtatcgtt
     6541 ggtttatccc atgcttatga agtttctgca gacggatcac tttcttcaga caacgtattt
     6601 attagtgcca atcccatttt caaatagaaa aacaaggctg attttcagcc ttgttttttt
     6661 gtttaattga acttcagaac tgcgtagcca aaagttgcta acacaagtaa tagtaagctg
     6721 accgctaaaa tcgttactaa atgtgtagaa cctgttttag gaacaataac ttgtggcaag
     6781 ttaggatcaa ccccaattgt cacaacattt gttttattag aaacattatc tactgctact
     6841 acggcttggt tatcaatatt tttttctgat tgtaatggag ttttagctgt aaatatcagc
     6901 tgaatttctc gtccatctaa aagattgtta tttaagaagt cagcggaagc ttcccacttc
     6961 agcgttcttg aattgctatc ataggttagt gtgccttcag aagtaatatc ttttcctgta
     7021 ctcttatcta ttacttgcgc agaaccgtca ttatatgtca aacgagcttc aattggatct
     7081 tgaatactaa attgtttgta gtgatctgac gcagcgtcta cgccttttgt gtgccatttt
     7141 tgtgtgacta gatattgtac ttcagatcct gcgtttaaag gagctgtcgg cgtacccttc
     7201 ttaccatcat ttcgtccgtt tacatctttt ccattttgtt gtacttcttt cactggaatt
     7261 ttagggaaat aaacggtaat gatatttgta tccttttcta ctttattaat gatcgacgtt
     7321 ccctgatttt tggctacact attttgattg gccaattcat tgacttttac attgatcact
     7381 aattcgtaag tttcgccgtt atacttcatt cgatttttta atgtatcagc tttcgctgca
     7441 tattttacct ggtgttttgt tttgtcatag gtcacttcac cagatacatc gaatttttta
     7501 tttgtaccac tttcaacgtg tgcatcgacg taatctactt cttttggtaa attatcgatt
     7561 aactcaaatc gatcgtaaac cgctagtaaa tccactccta atcgattcac cttctgtttg
     7621 attcgatatt gaatcgtgtc tcctacttgc aacattttat cgttcacgtt atttccattt
     7681 ttatcaaccc ctgttttttc aggttgatca ggaacaacac taaagattgt cgcagaagat
     7741 aaagtaaacc aggtttgaac attagaagaa ccaatcacaa acgtcggatt tgcttcagat
     7801 attttaaagg atacagtacc ttgaccaaac ttcggatctc ctaatttatc atgcaaatta
     7861 ttgaaatcat tatccgcttg tgtcagctta gagcttcctc ctgggtggcc acctaccacg
     7921 ttcagattgt tgtagaaaga tttaaattct gaaagaaccg catcttgtct gacataccaa
     7981 tctgtcgtat tcattttgtc atagtgggca tattctcctt taagatccgt gctttttcct
     8041 cctgcagggt tcaaagagtt aaaactgata aatgtatctc ctgaaaattg aacggggcta
     8101 ccgtcctcat atgtggctac tagctgcaca ttcatttgtg ttgaatggta aacaattcct
     8161 gagaaaagat tgtctgagat ccaaagtact gttctttttt tagatttact cattgcacca
     8221 ttcgtatttt tatagccatc gtctcgaaaa tgagtttttg tatagttgtt atctagtaga
     8281 ttccacggca acgtatccga gtataagtga atattagata gaactagctt gatattgact
     8341 tttttcccgt tatacgtacc gatttttcca tagtcaatat tgactttggt gttggttgtt
     8401 acgccttcta aaacaaggtt tgtttcaccg tattcctttt ggaaagaagg atagcgtata
     8461 tttttgtttc cctccactaa tcctacgtag tcgtctgtaa aaccaccttt gttggcatca
     8521 acatgatatt tgtaaacttt ggacgctccg tttacagtaa tatttgtttt tgcattagga
     8581 acatcttttg gaataataaa attattcttt acgttctgga ttggatttga cggatcgaca
     8641 ataacttttt cagcaaagac attggctgtt tttaacccaa acaatgtacc taacatcatc
     8701 attatgggaa aaacatattt taaccgtctg gtccacgagt gtttaaaatt catcccttca
     8761 tcccctcttt tttataaatg actagtgaaa ttccgacaat aacgatcaaa ttgatcgtag
     8821 taaataatgg attcctaatg agcttttcca taatatctag cggcatggaa gcagctggta
     8881 tgtttaaaat cctcattagg tatagttggt agcttggcaa aatagataat tgagaaaata
     8941 ataaaccgca gtacaaaaag actgcggtta aacaagaaag attgaataat aataatttga
     9001 tcagtttcat cttatttctt ccttaatctc tagaaaacaa gtgagtaaca aaatcccaac
     9061 aattctcaaa gaagtttttc tttacaccag tagaaacgat tttttttact tcttctttag
     9121 gttgcgaagc ttctgattta ggataaatcc acacatcctt taagaattca ccgttttttt
     9181 cagaaacagg tgttaatagc aaaatatcct cgctattaga aatgttttca ggacttgatt
     9241 cattgacaat ataataagct tgtttctgat ttgcctgtac ttctaccgag aattcaaaga
     9301 cacctgtttg ttgatcaatt gtctttgttt ctccattaga aactagcttc aattgatcac
     9361 tggatagttt tttcactcga tcttttaatt gggattcaat ttggtcagta gtgagatcct
     9421 taacatccat cttttgtaaa atgtccgata catcataaac agaaaacttc gcgccattta
     9481 ctccttcttg tttttcatgc ccctggttgt ctaattgttc tgaagaaata atcttttgaa
     9541 cgtgaatggt ctgtttgact atttgatcgt cttcagcaat tttcggttct tctgaagaat
     9601 ccactgttga cgaatcgacg gtttcatcgc tgctttgaat cgtgctgcta tctgacgttt
     9661 ggattgtttg ttctgtgcta tccgtgcttt cttgactgtc tgcaaacgtc aactgtgtgt
     9721 aggcagtgaa agaaaaaaga gcggctgcac aaacaaatag ccattttcta tttctcatgt
     9781 tggttaccct cctttatttt ttctttttat aaacaaatag cgaaccaatg atcatgactg
     9841 aaagaaaaac agtacttcct aaaagccatt tccaagataa tttttgtttc ttattttctt
     9901 catcttttaa ttctgatttt gtaaaggtta ctcgcttccc atacactagg aaacggtgtg
     9961 tgttgatccc cttaggcgta catgtcatta gcgttactcg atcttcattg ggatttggtt
    10021 ctaagtaagt gacaaagttt ctttgtagtt cgtctttttg cacttcctca atccgatcga
    10081 tttgataagc gtgctgctca ccatcaactt tgatataaaa cttttctccc tttttaactg
    10141 aaggcaaatc atcgaaaaga ttatctttat aaagtccact gtgccctgcg attaaaggat
    10201 ttttaccgtt tcctcctgta atatcgccag ttccttccgt aatccctaca ccattctcta
    10261 aaattttgtc ggaagttccg tcataaattg gtagttttaa agaaatactt ggaattgtaa
    10321 gaataccaac aggatcgcct aactcaatct tagaaacatc caaagaagaa tccgtttctg
    10381 ctgccgttcc tgttcgatcg attgcggcaa tctgctgatt ttgttggtat ttcgccacgc
    10441 tcgcttcagc aggcatcaaa agtaagacac caacagctga aagtaaccag aaagcaatga
    10501 tccatttacc catgattcgc tttttcttag ggtgtctgat aatcattagc tgatccttct
    10561 aggctttctt cttaaagtaa acaactgcag aaattgcgcc tgccccaagc aacaagcaag
    10621 agatcaatac gtaagattgg aaaccgttgc taccagtcat tggtacggaa gctttttgat
    10681 tatttttgat cgtgattcgg ttttcttctt tgtatgaatc tttgtctact ttgaaagaga
    10741 tctcttttgt taatttttga tagttttcag gagcttttgt ttcttccagt gagtaatctc
    10801 cttcagttaa accagtgatt tcaaaatgac cctctttatc tgattttagg attgctgcat
    10861 ttgctacatc gtctacccat actgcttctt tgacaccatc tttatctgta tcagtaagtc
    10921 caccgtagta cttaccttct gcattcttag ctgcaaattc tgcgccttca agaggagttg
    10981 ccttaattcc tgttccaaat agtccgctat cgacttttaa gaatttcgcg ccataagtca
    11041 caacgtcagc tttcgttttt tcgtggtgtt cttcctgatt aaatggattg ttgttataaa
    11101 cgaaatccac gctatttgtt aatggattgg caacagctgc gctgtcattt acatacatgt
    11161 tataagtcat ttgaagatct tgtccgtgta aacttgctac agtatcactt acttggccat
    11221 tatttacgat aaaatcgatc acaaagccat tttctgaatt ttggatctta taatctgtat
    11281 tttcttttaa taccactgat ccatctttat ttgttacttt gatatttgct ttagcagcga
    11341 cataagaaag tccttgtcct gctgtatccc cccatttaaa tacactgtaa ggagaagttt
    11401 cgcttttcac gccgtttact gtgataccgt ctgctccgcc tgcaatgtct gttgggatat
    11461 gaatcgttcc ttgataatta acggcatcac caacttggaa agaatgttct tgtcctgttc
    11521 catttgttac tgttttatcg atcactggtg ctttatagtt tacgtatgaa gcttttaagt
    11581 cacttgtcac gccatcattc gtaatttcaa aggttaattt attgtgcgca tcgttgcgag
    11641 cgtctgcgcc taataaatat tgatcggctg ttggttcttt atctgatccc actacgactt
    11701 ctgaaggaac ttccacaaaa tagtattttc ctaacgtcaa atcagtagca gtcagctttc
    11761 cttgatcatc cgaaacaaga tcgcctagtt tgcttccttt tccaggttct cctttataca
    11821 attcgaattt agcgccttta agaggggttt gtttgctttg ctctgtacca tcatcaccga
    11881 atttggttaa ttcaaaactc aacttagaaa caatattttt aggatataag tgaatgtctt
    11941 ttaaaaaacc tgaacctgtg ttgtcagtca ttggagcaat gaccaccatt ggttttgctt
    12001 tttgagttac taatcctgct gcggacttac tctcgtaaat aacatacaca tttccttttg
    12061 agttcacgta cgctggttga tccgcaaaag taatctcacc attttcatct acagctgaag
    12121 taattttatt ggttgcattc ttgacgtact cactgttaga tcccttgtct tctacgtctt
    12181 tcacgatttc gtccactttc gcgttggtta gatcagaatc ttcagtcggt aatacttgat
    12241 ccgtaatatt tcctaacgta aactcaacat caccataatc tgccttgttg tatttcgtta
    12301 cacctgtagg atactgatcg tgcgtataac catcattttt gatcccgtca atatcaacat
    12361 tcaattgcgt actttgatcg tacattaatt tatgaaccgt gatattgacc ttctctggtg
    12421 gcgttttttg cgtgacatct tctgcatgtg cttgataccc ctgaaagcag cttgcaatga
    12481 ttcctaacat tccaacaagc attccagctt tttttacata tcgatttatt gccattttta
    12541 ctctcctcat ttcatatttc aacgactcgc gttgattaaa accttgttat tgtagctctc
    12601 cctgtaccac gtatctttct tttccttgtg acgtatagac acaagtaaac aacgttaata
    12661 agggtttctc tcctttcttt ggcaaagaca agaaagagtt ctcttcagga acgccatcga
    12721 ttaatctaaa gtacccaggt acgataaatt tacgcgttac cttgtaacga tagacgccat
    12781 cgttactaac taagtccatc acctccccta atgacaactt ttgaatatca gaaaataaaa
    12841 cacctggcat ttccatgtta tgacctgcta ggacatagtt tcctttgccc atttcagcat
    12901 cttcataaaa ataagtagcc gctccaagac tcaaagtgta ttgatttgcc cctttaaaaa
    12961 tcggcaatgc taaaccaagt gcaggaatct gaatttgtgc aaatacttgt ttattgacgc
    13021 ccatttcgat tgcttctttt tgtatggaca acatttgccc caaagacata tcattattga
    13081 cgttcgttgc atcctcctta taactctttg catgtgcatt gatttgatct acgggcatct
    13141 ttttttctat attttgctta aacacctctc cttcatgttt ttggtagcta acatagccaa
    13201 acacactgca aacgacgatt aaagcgactc ctaaaaaacc aaataaccat tttttcatcc
    13261 atctgcctcc tttcagacaa aacaaaaaac actttttcac aacgaaaaag tgttttctct
    13321 tattactatt ctatttcatt tatctggtgg ttttatattg gtgtgtagcc attgctaaca
    13381 ttaagaacac aattggtacc caactgattg tagctaatgt ttcttccatg aaagattgac
    13441 acatgatcgc taaaaaagcc cacaagaatg ttagttgtcc atttgtcagc tcacattttc
    13501 ttacgagcaa ccataagaaa ctaagcaaaa gaatcatcga tagagcaaaa ccaatcaatc
    13561 catagtgatt gacgagtgcg tgatacgtat tatggttacc tagaatctga tttcctctat
    13621 ggaaaaagaa aggtttcatc cctacaaata tttgtcctgt tttttcgcct aatgtttcat
    13681 agaatttgcg ccaaatttct tctcgtcctg taaataaatg aactttgtct gacattgcag
    13741 caaaataaga aatcggtaaa gctagaaccg aaactgctgc atacatccaa aaggacaagt
    13801 gtgtgtttcg aaagatcttc ttaggtaaaa tttctaggat aacgaagata acaagcgcgt
    13861 ataatgctgc tttcgattgg caaacccaaa tcgttgcccc agcaagaatc aacgctggta
    13921 atgatagcaa tcgcatgtac cattttccaa atgaactagc aaatcctgtg ataagaaggg
    13981 ctaatgtcat taaagaacta cctatcgtat ttgtattgat ccaaatatct gataatttgt
    14041 tcgatggatt ccaaatactt tgtccttctg gtactggtat ctcggtaaat actcgataaa
    14101 ccgttacgag taaaaagaca tagaatacta caagatacaa gctacgatca aatacagtaa
    14161 attccgtcca ttttacaatc aaaataatgg caataattgt cggaacgatc agatcaccat
    14221 agaaagtatc tcctcggtag cttctaaaaa aagaaaagaa aaggtaaaaa agaatgcctg
    14281 ctgcaatgaa gaatagatcg tttctcttta ccttgtacag attcaaaaga aacaaacagc
    14341 ctacaaaaaa cgtcactaac tgtgcagcat tatcataaat aaataatatc gtaggaggat
    14401 ttaaccccac cgtccatatt aaataaagaa tggataccaa cagtaacaga aaaatggcac
    14461 tcattttatt gatcaatttt tctacaagtt cttgaatgtg actcacttcc cttatttatt
    14521 gattttttct acattgacta attcgcactg gatcacatcg cactttttca tattatttgc
    14581 ttcaaagtct aacagtgtga gtagtggttt tttacctgct tttggcaagg ataaaaagga
    14641 attgttttcc ttagattgaa ctacctggct gtaatcataa atttttcctc ttttggagac
    14701 ttcatactga tacttgtaat gagcatcgat tagatcaatt tcttctcctt cggataaatc
    14761 aatcatatcg gataataaaa cgcttggtgt atctacgtta taaccagcaa gaatataatt
    14821 tccatttccc atttcagcat ctggataata agtagaagct actcctaaac taagcgtgtc
    14881 gctattcgct ccttgaaaaa cagggagaat aaatcctgta gaagaaaaaa caagttttcc
    14941 agcaatttca cctttgagat ccttttctaa tgcctgtttt tgattagtaa tcagttgtct
    15001 cttagaaata tccgttaaac tggttaaatt atcttgatag gttttagcct gttcctgaat
    15061 atggattgtt tttgttacat catctacttt ttcagcgatt ttgtcctttt gataaccttg
    15121 ataagcaaaa taactaaaaa ggagaaaaac aatgattacg cccacgtaag gattaaataa
    15181 agttttattg tttttattca tctatctacc ttctatatat taattaattt acctacaact
    15241 aaccaagata aaccacgtta aattttacta ttctttttat tcaataacaa tgccacatca
    15301 taattgatca ttttcatatc ataatcgtca agaaacttct aataatagtt ggcaattaga
    15361 acttgttttc acataagttc gtctcaactg ttcaaaattt ttcattgatc ccaatagaca
    15421 ggctttctcc tttcctgtta tctgcatatc attgatatat tgcatgacag ataatctttt
    15481 aaggtgtttt tgtttcatca tttttagcaa cttttcttcc atttcttttg acactttttt
    15541 ccaatttacg ctttctttac aattcatgag ttttcctacc ttccctgttt tttgcaaaaa
    15601 taaaaaagcc tatgatcaca tacgctctac acttcagtct tgggttatct ttttctttcg
    15661 tttaattact ggccgtgctg gtttcaaatc cttgattcca ttatgggttc tccaataatc
    15721 gaattctttt cgtaatcttt ctttttccat atctgttcct ttagataggg ctttgaatac
    15781 atctttaggt gaataaccac gagctaacag ctgtacatac cttccttttg tcaaagtatc
    15841 catatccatc gcctctaaaa ctggtcgcgc catctaattt tcctcctaaa taaattcctt
    15901 actcaatgcc taaggtaata ctaccttttt attaatcgtc gtgactcctt ctaagccttt
    15961 atctgtaaaa tttattcctc cagtttttat tcttctttat ccgctacaaa ttcaatgatt
    16021 tcaacgctga caatataatc actcaaatat gaccaagtat cttcaacaga taattcgtct
    16081 ccattatcat tcataagcgt cattttaaac cattcattac cttcatcatc ttcaggtagc
    16141 aagccgaatc caattggatt atcagtcaat ttttgatagt ataaatcatc ctcgtctaat
    16201 gctaaaacat ctaatccttt acaatttccg cctcttctaa acgtcacaaa tcctttgtaa
    16261 tcccaacgtt ggaaagaaac cttaatagta tgtgtgccca atcgtatatt cggatcataa
    16321 tttttcattt gtcattcctc cattacgtaa atttcatttt ctctatgttt tatatcaatt
    16381 ttttcacttt attcaggact cgttcatatt ttatcgtttt tcgtttactt aaaaatacat
    16441 aaaaaatatc gactcgttta tggcgtccga aacgagaaac cctagtagaa atcggtaaat
    16501 gctcgattga tccaatgacc aacgtcctcg caagtatcta catgtactgc agcacacgac
    16561 acaatttctt gtgcgtcctc cccattacga gaagacctac tccttattcc atgagtttgc
    16621 gtcaaagcct agatccctta gtagctgctc atgattaatc taggcgctat tctaacttgt
    16681 ctaacttcta aattccctct tgtttactct gtgcatatta tttacacaaa ttcatttcac
    16741 cactatccaa acaagggcat ttactcgatt gaccaatttt ttacgttacc aatcgtaaaa
    16801 acctaccccg tcaccccccg aaaggaattg ttgatagatc aagtctactc cttatttttc
    16861 tagtaattct aagttctttt agaagtctcg acaatatttt caagcaagcg aaaaacgata
    16921 aaatacaagt tatgagaatg atcaattcag ctgattaaac gccccatccc ttttgcggta
    16981 caacgcaaga ctccattttt tcttcgacca atcagtacac cgttttggtc ataaacatgt
    17041 ttgattgttg gatatagttc ttttaaaggg ataggatctt ttaaaattat ttgtttttgt
    17101 ttaccagcgt aataaatcat ttcctctgag actttgtctt tctggattat atatttctta
    17161 cactgcacaa cggttttact ttggccagtt gatagtttct tcgtgatttt ctctgtagcg
    17221 gtacaccgtt taccgtagtg acaaatatct tcgagactca aaattcctgt atatgacata
    17281 aaataatcca cccacttact ttaaatattt ttaataagtt tttcttgtta tttttcaaaa
    17341 atagagaatt gattttcgtt catgacaaac aaaaaagagg gaacgcatcc aaacatgcgt
    17401 tccctctaat ttcagcgttc gtcatacggc aaagagccac acggacattt ttataacatt
    17461 atgcttaggc atagattcat cgtaatatca cgtattttta accttaacac agccaaaaaa
    17521 agtggtatca cttttgaata tctgttatac taaatccgtt gcgggtaata ccgtaacact
    17581 gaaaggtaaa cgcattaagg gattaaaggt tgtcttaatg ccacctgtgg acgtcgacga
    17641 aggttaccag ccttccgagt ctcacagggc ctttcttttt tttgtatttt caattgtcca
    17701 aatttatcgt ccaaaagtgc agaacgaaaa ttaattcatc acaagcgtag cagacaatta
    17761 aatttaaaac aactaaattt atacaaaaaa atgtaagcga ataatattcg tattgcctga
    17821 aaagaagtaa tatcaaggtt tttagctttt ttaaaaaatg aaattacctc tcttcgcgta
    17881 ttattataac taaaaaacag caacatgcaa acgtttgttc tcttttttgt gttggaaatt
    17941 aattattaac tattaacact tatgacgtaa aaagctacgt ttgtgatttt tatcataata
    18001 ttttaactca taaattctat taaaatagct atttctttgt aacatttgta atataattag
    18061 aataataaaa aatttttaat tttaatgcta ctccatgaag caacaatcaa tttgtcagtg
    18121 aaatttcact ctaaccagtc tttcgtaata gtttttggga agctttcaga attcaaacgt
    18181 ttttcacttg atactttagc agctattggt ttttcgataa accaattttt tacatagaca
    18241 aaaatcaggt tctggatatt ttcaactttt tcggttttta atttttgata ggcttttaac
    18301 agtgtcgtgt ataattcttg ttctgcattg acataataac tatcgagttc ttcaaaaatt
    18361 attgaaatac cactttctgt ttcggctttt ttctttgcat tatgaatagt ctggacagtt
    18421 ttttgagctt cactgtaact tgaagaaaat gtttttatta aatttaatac tcgttcaggg
    18481 ataaacgtag caatgctgtc gtttgtcata attgtctcaa aattgtctaa caacaattga
    18541 tcttgtaggc ggtctttttc agtgtctata ttgtgtctat tagtgtctaa tatattatta
    18601 ttaagttctg gtatgatttt cataccctct gatttatcaa cgttttggca cggtatgatt
    18661 ttcataccct cttgagcccc aagggattca gcgtctgatt tttcgtcgag ggtgggtatg
    18721 attttcatac cctctgattt atcaacgttt tccctattct ctctatcaaa tttttcgagt
    18781 aagtagatat cattttctga gacttttaat tctgctagat atagtctatt aggattattt
    18841 ttccctaact gtttgttaaa tcccatctgc ttttgtaata ataaaccaaa ggattccaac
    18901 tcttttttga ttgctatcgc tttttgtttt tggcagttta atacgctaca tagttcattt
    18961 gtcgtataag taaaataaac attaccttct tcatcgattt gccgtttgct gattgcgatc
    19021 tctaatcttg cttttaaaag catataggca atcttagttg aatctttcat ttttttgtat
    19081 tcgtcagaaa caataaagac ttttggaaat tgataaaata attcgttgta aactctatcc
    19141 gccttaaaaa aattaaaatc agtcattgta gatcctctac tttcacattg ttttatttat
    19201 gtaaaattac ctactctttt cgaaaatagc aaagataaat aaaaaatgca aacgcattaa
    19261 aactgttttt taattaaata ctacctaaaa tcagaaataa aatgaattat gtactacctt
    19321 taaagtcatt aagaactact ttaaataaat attatttata attaaatact accagaagaa
    19381 cgtatgaata aaatttagtt ttaaaattaa agataattaa gtactaccag tgtcaaaaca
    19441 aaaaataaat taagaactac cttatgcata taaaacatac taccattact agtaatatat
    19501 actaccttat ttcagtagta tatattatat tcttcttata agacaaggct ttaggctaga
    19561 aaacaataga ttatatacta ctaaaaaata caataagtac taccaatgtc agatatatat
    19621 aataattatg tactaccatt aaaattaact tatttaataa gatactactg tgttaatctg
    19681 aaaaaaatta ctttaaagta gttacatact acctgttaaa ttagatacta ccattaatac
    19741 ttaaattaga tactacctat atttatatta agtactaccg ttctaggaat aagataataa
    19801 aaaaaaacta ccaaattgca attaaatact acttaaaatg taaaaaataa gaactaccca
    19861 aattaggtag ttcttaataa gagaatatca gataaatttg tacaagtcat aaaaaaatta
    19921 atcttaaatt tttaaatata tatacctgtt aattataaac tactttattt aggtagtaca
    19981 taattaacag ataaaactac atgcttgtag tttgtctagc taatgagttg catatgattt
    20041 atataaaggt gtgcagcata acttagttga agttaagaga atagaataaa tattttttgt
    20101 tttgctaata attaaacact acctaaatat ggtagtgttt aattatataa tattcatttt
    20161 gttacaaata atcgtattat aaaagcataa caattgggat aactattttt tagattattt
    20221 aagtactact taaattaggt agtacttaaa ttttggttta aggtagtagg taattaagaa
    20281 ataatatata tcttctttta taatagaagg ggagaggcct agttaaaagc agcgacaatt
    20341 aataacaatg tatttaatgc ttcacaaaat ccatttggtg gacaatgcat tgttattagc
    20401 gatgatctac cgttctaagt agttttttct attggttgca ttcgtgacta attatggtat
    20461 aattatgagt aacaaagagg tatttcatta tatcatcaaa ccccatcagc gtgtaggctg
    20521 atggggtttt ttttacgttt ctatattata gaattaactg gtaggcttac tgtctttttt
    20581 ggcaattttg caatcaagcc acttgcagat gtagtgtgca gttacctctg caaatggctt
    20641 gattgcaaaa acaaaatcaa aaaggtattt cattatatct cctcctcccc ttgccagatt
    20701 aggccggggt agcagacagc aaaactatta taacataact gaaataccta aatgacatat
    20761 acagatatga taatttatgt attgattttt ctaacaaaag cacatatttt aatatatact
    20821 acctatttta ggtagtatat atttttagat acaatatcga tcagttttga ggaaatgaaa
    20881 ttctagatat tttttgctac atagagttac tttcaatatt ttttaacgta attaggcaga
    20941 agtcactcat cctctatagg tttgtgatga aattgctatt gatccattta agtaagagca
    21001 aaaaactgga ggtttatcag gtaattggtc taatggattt aagtatgcgg tcaccgtgta
    21061 tagagttgct tatgagattc aagaaaataa agttattcca gtattgctat atggaacaca
    21121 taacaatttt tatgaattag ccgagaacac tcgcaacttt attcgtgtag atgaatcggc
    21181 ttcggttgag ttataacttt agctatatca atcaaccgac cgacatatgt taaatctata
    21241 tataataaaa atacctactt aaatggatgt taacggaagt gtatggtgag tagttcactc
    21301 gtattttgat atcgtttgta tatgttttca gcgttctaag tggcttattt tgtccaataa
    21361 taatatggag tggaatccct taagaaacac cgttggcaat tgtcgttata acatgttata
    21421 atttatttat caaaaactaa aagaagtgtg ataacatggg aaaagaacta aaggttagaa
    21481 agatcggcaa tagcgtggga gtgatccttc caagctctct tggattaaaa agcggagaca
    21541 ctatccaagc caaacaagaa ggcaacttaa tcatattaga tactactcaa atagcaaaag
    21601 aacacgatcg caaattgatt gaagaaagtt tccaagactt tgagaaaggt ttaacagttt
    21661 cagaaattga aatggtaaaa gctttcggaa aatacggctg gagtgaatag atgaaagagt
    21721 acacgctagt ttattctaaa agtttccaga ccagccttga aacgataata gaagaatggg
    21781 aaaatgagct tgctctttct ccagccagca taaaaagatt tgtaggtgcg atccagaagg
    21841 ctttagaact aaccaaaaat tttccaacta tgcatgagga agtttccgaa atctatggaa
    21901 tggatatccc aacatatcgg atcgtgatcg gcaaaagcta tgccttattt tatcggatcg
    21961 accatgaaaa aaaagagata cttgtaggac gtattttcca atctaaacaa atgaaactag
    22021 gcttttaaca ataattaggc aaaagtcgct catcctctac aggtgggtga ttaatgccgc
    22081 tcgatatggt tgttaaccgt cggttactcg aagattgata tataagactt agtacctttt
    22141 tattttgctc catgttatgg ccgaaggtct aaagatacaa tcattagtct agagaaaaat
    22201 taagaaccgt aggaactacg gggatcgctt ggtgaataag agacactgct attagtgaaa
    22261 aaataagata tcaagtacgc tctattccca aaaatttcgt gactttactc atgagaggtt
    22321 caagtagtat atttttaatc aaaattgacg taacttt
//
LOCUS       DAFBSV010000046        22218 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.047, whole genome shotgun sequence.
ACCESSION   DAFBSV010000046 DAFBSV010000000
VERSION     DAFBSV010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22218
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.047"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            171..515
                     /locus_tag="LLB18_001615"
     CDS             171..515
                     /locus_tag="LLB18_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBK5244618.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            516..935
                     /locus_tag="LLB18_001616"
     CDS             516..935
                     /locus_tag="LLB18_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBK5244619.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1027..1377)
                     /locus_tag="LLB18_001617"
     CDS             complement(1027..1377)
                     /locus_tag="LLB18_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244620.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1343..2674)
                     /locus_tag="LLB18_001618"
     CDS             complement(1343..2674)
                     /locus_tag="LLB18_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HBK5244621.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2930..3496
                     /locus_tag="LLB18_001619"
     CDS             2930..3496
                     /locus_tag="LLB18_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK5244622.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3641..3728
                     /locus_tag="LLB18_001620"
     tRNA            3641..3728
                     /locus_tag="LLB18_001620"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3673..3675,aa:Ser,seq:cga)
     gene            4062..5036
                     /gene="bsh"
                     /locus_tag="LLB18_001621"
     CDS             4062..5036
                     /gene="bsh"
                     /locus_tag="LLB18_001621"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBK5244623.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
     gene            5361..7256
                     /gene="asnB"
                     /locus_tag="LLB18_001622"
     CDS             5361..7256
                     /gene="asnB"
                     /locus_tag="LLB18_001622"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBK5244624.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(7451..7897)
                     /locus_tag="LLB18_001623"
     CDS             complement(7451..7897)
                     /locus_tag="LLB18_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBK5244625.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            8125..8274
                     /gene="rpmG"
                     /locus_tag="LLB18_001624"
     CDS             8125..8274
                     /gene="rpmG"
                     /locus_tag="LLB18_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBK5244626.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            8362..8880
                     /locus_tag="LLB18_001625"
     CDS             8362..8880
                     /locus_tag="LLB18_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBK5244627.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(8957..9913)
                     /locus_tag="LLB18_001626"
     CDS             complement(8957..9913)
                     /locus_tag="LLB18_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK5244628.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            10079..10885
                     /locus_tag="LLB18_001627"
     CDS             10079..10885
                     /locus_tag="LLB18_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5244629.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            10882..11871
                     /locus_tag="LLB18_001628"
     CDS             10882..11871
                     /locus_tag="LLB18_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBK5244630.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            11868..12872
                     /locus_tag="LLB18_001629"
     CDS             11868..12872
                     /locus_tag="LLB18_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBK5244631.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            13004..13546
                     /locus_tag="LLB18_001630"
     CDS             13004..13546
                     /locus_tag="LLB18_001630"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBK5244632.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            13566..14264
                     /locus_tag="LLB18_001631"
     CDS             13566..14264
                     /locus_tag="LLB18_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBK5244633.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            14285..14497
                     /locus_tag="LLB18_001632"
     CDS             14285..14497
                     /locus_tag="LLB18_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HBK5244634.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            14497..15459
                     /locus_tag="LLB18_001633"
     CDS             14497..15459
                     /locus_tag="LLB18_001633"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HBK5244635.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            15477..15872
                     /locus_tag="LLB18_001634"
     CDS             15477..15872
                     /locus_tag="LLB18_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBK5244636.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            16035..16400
                     /locus_tag="LLB18_001635"
     CDS             16035..16400
                     /locus_tag="LLB18_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HBK5244637.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            16397..18208
                     /locus_tag="LLB18_001636"
     CDS             16397..18208
                     /locus_tag="LLB18_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HBK5244638.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(18270..18437)
                     /locus_tag="LLB18_001637"
     CDS             complement(18270..18437)
                     /locus_tag="LLB18_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HBK5244639.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            18685..19674
                     /gene="galE"
                     /locus_tag="LLB18_001638"
     CDS             18685..19674
                     /gene="galE"
                     /locus_tag="LLB18_001638"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBK5244640.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            19686..21170
                     /gene="galT"
                     /locus_tag="LLB18_001639"
     CDS             19686..21170
                     /gene="galT"
                     /locus_tag="LLB18_001639"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HBK5244641.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            21194..22174
                     /locus_tag="LLB18_001640"
     CDS             21194..22174
                     /locus_tag="LLB18_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5244642.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
BASE COUNT         7208 a         3806 c         4620 g         6584 t
ORIGIN      
        1 taaaaaaagc gttagcaact atgcttaaaa agcatatcga ctgaataaac taagcattgg
       61 acaggctgaa agactacatt taaaatgaaa tgcgaagaaa caatagaaaa taaagttgcc
      121 ttagaaccat agttgaatca cctaacagtc gtgaagggag aataagagaa atggcagaaa
      181 aacaaaccgc aggacgagat caattaggag attttgcacc aaaatttgca gaattgaatg
      241 atgatgtttt atttggacaa gtatggtcca gagaagaatt atctgctcat cagcgtagta
      301 tcatcaccat atctgcatta atttcaggag gaaattttga acaattgcca gctcatctga
      361 agattggcaa gcaaaatggc attactagtg aagaaatagc agaaatcatt acccatttag
      421 ctttttatgt aggatggcca aaagcttggt cagcttttag tttagcaaaa gaaatctatt
      481 tagaagaaaa tagcgaagat aagaaagagg cgtaaatgac gacaaaacac gaagaaatac
      541 acaatggcgt gatttttcca gcaggtgaaa aaaacgaagc ttacgctcaa gtatttaccg
      601 ggcaaagcta tctgaatatg ttagtgaatg atcccgaagt ttctgttggt gtaggtaatg
      661 taacttttga accaggttgt cgcaatcact ggcatgtcca taaagacggc tatcaaatct
      721 tacttgtgac cggaggagaa ggctggtatc aggaagaagg aaagccagca agacgattaa
      781 tggctggaga tgtcgtcgta acgcacaaag ggattaaaca ttggcatggt gcgacaaaag
      841 acagttggtt tgaacatttg gcgatcactg ctggtaattc agagttttta gaacctgtaa
      901 cagatgaagt gtatgaagga ttggaaaatc aataatgtca agcttgaaca gctcctgaaa
      961 gtagatttta atcgaacttt caggagctgc ttttttgatt cagtctttta taaatagaaa
     1021 atagggttaa taataggaat gagaagcacg tcgaaagatc ttaatattga taatcggctg
     1081 ggcatacatg atttccacgt catcaatcaa actacctaac agatgataat cttcccgatc
     1141 atgtcgggga ttacctaata gttcttgata atagatttcc atactagggt cccgaggatt
     1201 gttcagcaaa tcagcaagta catctaaatc ttctggctga gtttctgccg taccctgtat
     1261 ctctatgaaa agcccttcct cagcaaattc tactccaata cgtatttcag ttatttcatg
     1321 ggaatataaa taagtaagaa gctcatcgat gattcttttt gataattctt tttccaagtg
     1381 tctttttttc ctttctgaca gcggtaaagt tatctagtat cggtacaagg atacctgcaa
     1441 cgaaaccagt tgaaaaacca ctgttatata gatttagtcc tccgtgcaaa gtgctgacgt
     1501 tatggacaag agcaatatgt agtacaccag ctattacacc gtaaaaactg ccgtaaaaac
     1561 cgcttatggg cgcgagacct gtcccaaaca cagctgcaac aagcatgcca gtactggtga
     1621 tctcatgaaa agttccaaac aaagaagcaa taaatattcc gactagtatc ggaaaactgt
     1681 tttttaaatg acaaccaaaa gcactgaaac ccaccgcaga taaaatagca ccgatgacag
     1741 gtccatttaa ctgaccgcca accagcaaaa cataagaaga cagcatcaga ccaactaagc
     1801 ctatgttgat caaagtagca ccaataccag aattagcaat gaaatcagtt gtcaattttc
     1861 cagatgaatc gaaaatttct cgaatcccca aaagccgaaa ggaattataa tagaaaccaa
     1921 ttccgactgt cagcgaaaaa aagccaaaaa taatccaaat gagaggaaag tgatattcat
     1981 tgaaaaccaa tgtattttcg acgattgaat agctgaataa cctcaaaaca gcagtaaaag
     2041 tcatcgcaat caacccagag gtgaatccaa tattataaag tgtgaatcca cgatggaaaa
     2101 ctaaagtttg agcagctaag ggcggaagaa gtagaccaat tgctatgcca gctaaattcc
     2161 ccaataaaat acctatcagt aaaggaaaac gcataccaaa agtgatataa ctaacgaccg
     2221 gtgataatgc gctaccaaac agtccgatca tgatgtactg agaaaaaggt ttattgacaa
     2281 atacagcgta tagatacaca cctaaaatga ttgagataga attataaagg tttttgccaa
     2341 aaaaagagaa accggtaact gttagaatcg aagcaaataa gggaccgttt aaaatcacct
     2401 tgtgccgata agctaaaagc acagaaagta aggtcaaaat ccctacattt atgaatgcgc
     2461 ttccgaaacc gcctaaagca aaataatctg tcaaaagatt gcttggcgag gtaagaatag
     2521 ttagcaatcc actccaatta tcagtaggag tattagaaag caagccaata aaaagaaaaa
     2581 aaacacctgt aaaaccaaga taaaaatact ttcttttctg tgaaacgatt cgtttttgag
     2641 gatgaatata aataacgtca gtttcgtttt ccattacaca ccttcttttt cattttcttt
     2701 aactataact tgaaatgaaa gatttggaca actatcattt aggtcaaaac taaaaatgta
     2761 agggaaccca ttgaatttaa ccaaattttt ttaattttgc aaaaaaaagt taaagaagac
     2821 tgaaaaaaaa tttaaaatat aacgttttga gtaaaatgtt tgcaaaaaat gctaaaaata
     2881 gggtacaata aaacaacata tactgcagta aagaagtggg ggagttttaa tgagaagaaa
     2941 agtctatacc aaggatcaaa ttctaaaagc tgcttatgat gttgttgcaa aggaagggtt
     3001 taaaggattt actgcgagaa atattgctaa aaagatgggg atttcgacac agccgattta
     3061 tctggaattc aaaaacatgg aagatttaaa aaatacgttg ctggattcta tctttgaaca
     3121 actaaaagaa gatgttttcc ctattgaacg tactggtgat aaaatcattg atctcggttt
     3181 gaactatatc tactttgcaa aaaagcatca tagtctttac atggcattgt acattgatga
     3241 acatggggac ggaaagaaaa tgcatgattt ttcatacaat tatttccgtg aaatagttaa
     3301 agaagatgaa agatacaatc aattatcgga tgaatatgtc gatgctctgc atactggtac
     3361 atgggtagca gtgactggct tagcgtcatt gatgtcatca aacatcatgc atccaacaga
     3421 agaacaaatc attgcactga tcaaacggac aattgactcg attttagcat tagataatcc
     3481 tgaaataatc agatagtgtt ctatcagtat gaatttgatc ggtaagtccg ttggctgcaa
     3541 actgtcaatg gacttttttg ctaaaaaaag cgatttctgt tatttatcta ttagaaatag
     3601 gcttgacatt tcgtgaaaaa agtttaaaaa tagtacttac ggaaggttgg cagagtggta
     3661 atgcaccgga ctcgaaatcc ggcgaaccgg ctaataccgg cgcgcaggtt caaatcctgt
     3721 accttcctta tatcaacgat tagaggttgt gaagaagctg tcctgcatca agtaataaga
     3781 acggccaaac aaaaatagct tttcctattt tttcgtttga ttgggcttat taccgcagat
     3841 gcaagctttt gaacaccgtt tgttcggaat aaggggctgt gacaagactt ttgtcacagc
     3901 cccttattgt tgtactttta acctacaata ttttttgatt ccccctgagt actatttttt
     3961 ataaatgcta gtaaatcaat cttctttggc ctttttttga taaaaaaaat actagatgta
     4021 agataaaagt gtaaaaacga tttgttttag gacgggaaac gatgtgtacc gcaatcactt
     4081 atgcaacgaa agaccattat tttggaagga attttgatta tgagatgtct tataatgaag
     4141 tggtcactat tactccaaga aattatcgtt tcgattttag aaaggtaaaa aatttagata
     4201 aacattatgc aatgatagga atagcagctg gggtatccaa ctatccactc tattatgagg
     4261 ctacaaatga aaaagggttg agtatggcag gactgaattt tcctggcaat gctgattata
     4321 aagaattaca agaaggaaaa gataacgttg caccatttga gtttattcca tggatactag
     4381 ggcaatgctc aaccatagac gaagctaaag aattattggc tactatcaat ctagtcaata
     4441 tcgattttag tgaaaaacta cccttgtcac ctttacactg gttattagct gataaagaaa
     4501 aatcgatagt aattgaaagt atgaaagatg gacttcattt atatgataat cctgtcggtg
     4561 tgttgacaaa taatccgcca tttgattatc aattatttaa tctgaacaat tatcgctcgc
     4621 tatcaaatgg aacaccagaa aatcattttt caaaccagat cagcttgaat gtttatagtc
     4681 gtgggatggg aggattgggc ttacctggag atctctcttc tgtttctcga tttgtaaaag
     4741 ccacatttac taaaatgaat gctgcatcag gtgattcaga atctgaaagt atcagtcaat
     4801 tttttcatat actaggctca gtcgagcaac aaaaaggagt atgcgatact ggagaaagaa
     4861 aatacgaata tacgatttat tcttcttgct gtaacgttga taaagggatt tattattatc
     4921 gtacgtatga agacagtcaa attactgctg taaatatgaa taaagaagac ttggatcgtc
     4981 atgaattggt cagttatcca gtcataaaag agcaacagat aaactatgtc aattaattaa
     5041 tgaatagatc cgtttggtat catattttct gatacagtca taattagaca cgatctttag
     5101 gtcgtgtctt tttttgctgg tttttttgga aatagcatcc actaatattt ttttaacacg
     5161 aagagaataa ggtagcctca aaaaagaaaa catggtaaat tagatattgg gactttattt
     5221 tctgtaaaaa cagaaacttt catcttttgt tttcacgtga cgaaattgta agagagaaaa
     5281 tattcgtccg ctatttattc tatgataaga tgcatatgaa tgaaataaac agtaatttta
     5341 tattaggatg tgaaagttaa atgtgcggta ttgtaggttt tgttaacgac aaggacaaca
     5401 aaaaaacaat tattaataca atgatggatc gaatcgttca ccgtggacct aatagttcag
     5461 gagaatatat cgataaacat gttgctttag gattcagaag attaagtatt attgacttag
     5521 agggcggtac tcagcctatt tacaatgaag atcggacaaa gatcattatt tttaatggcg
     5581 aaatctataa ttaccagcct ttgagagaag aattgattgc agctggccac gtttttcaaa
     5641 cacatgcaga tacagaagtc cttttgcatg gttacgaaga atggggaaca gaattattgc
     5701 aaaagatccg cggaatgttt gcttttgcta tttgggataa tgaaaagaat gagttattcg
     5761 gtgcaagaga ccactttggg atcaaaccat attattatgc agaaatgaac ggaacattta
     5821 tgtttggttc agaaatcaaa agttttctgc ctcatcctga ttttaacaaa gaattgaaca
     5881 aagaagcgtt gaaaccttat atgactttcc aatattctcc attaaacggc gaaacattct
     5941 tcaaagatgt ctatcgtttg cctgaaggcc attattatac gtataaagat ggaaaaatag
     6001 acattcagca atattgggat gcagattttg aaacaaaaga aacgcattcc cgacaagaat
     6061 ggatcgaaaa aatcgacgaa accgttcaag cttctattga agcacatacg gtcagtgatg
     6121 tagaagttgg ttctttctta tccagcgggg ttgattccag ttatgtaacc tctgtattga
     6181 aaccagatca ttctttctca atcgggtttg atgataaaac ctataatgaa gcgattgaag
     6241 ccagaaaact aaccgaacta ttggacttag ataatacagc agcagtgatc gacggagaca
     6301 tgtcgttcaa agcattccct ttgatccagt atcacttaga tgaacctgat tcaaatcctt
     6361 cttgcgtacc tttgtacttt ttagcaaatc ttgcttcaca aagtgtgcgg gtagtccaat
     6421 ctggagaagg ggcggatgaa ctgtttgcgg gataccaaac gtatggattc catacgaatt
     6481 caaaattcat ccgtgtgatt gctcaaggat tgaaaaaatt accaaaagga acacgctata
     6541 atttaggacg taaaatcgga aaaatgaaaa atttccatgg acggatccat ttatatgaat
     6601 cacttgctcc tgcaaaagaa tattttatcg gtcatgctcg agtgttcgaa gaatcagaag
     6661 catcagaagt gttaacacca aaatatcaaa cagcaccatc tgtggatgaa atcatgactg
     6721 ttcattacga gaaaacagaa ggaatcaaag atgaagtcaa taagatgcaa tatgtcgatc
     6781 ttcatcaatg gatgccaaaa gatatcttgt taaaggcaga taaactttct atggcaagtt
     6841 ctttggaagt ccgagtacct ttattggata tcgaagtcat gaaattggct caacaaatac
     6901 caagtaagtt tttattgaat caaaacaaca caaaagatat tttcagacaa gctgcgaaca
     6961 aacatcttcc ggaagaatgg tcgaatcgtg tgaaattagg attccctgtg ccaatcaaag
     7021 cttggttgaa agaagaacac ggctacgaac aagtcaaagc attattcgaa gcagattttg
     7081 caaaagaatt ttttgatcaa gaaaaaatca tgaagttgct agatgaccat cacgaaggac
     7141 gtaaagaaga gcaaagaaaa atctggacaa tcttcagttt cttgacatgg tataaagtct
     7201 actttgtaga tgaaacgatt ccgcaagcag aagcaatcga ctatgtgact gtttgatgaa
     7261 aatcaaatat caataaaaaa gaggttttct cctaccgttt aacactgagt gataagaaac
     7321 aatttcaaaa aacagctctt cccgttttat agatattatg acttatggtt cggagttggc
     7381 agaggaacac cattgtttcg aacataaggg ggttgtgaca cgattttcgt cacaacccct
     7441 ttacatatgt tcaataatcg atttcttttt cttttgtccc atctttttta taaatgaaca
     7501 aagttgattc tttgttttgt gctacttgct ttcctttttc gattgcttct ttttttgtat
     7561 caaaatggtt gcttgccttt tttgcccctt tagatttcac gatccattgt tcttcctcat
     7621 attctacgat cacatctgaa tcaagcagtt ttccagcacg aggattcgta tcgtgttcat
     7681 ccgtcttgct tggatttttt tctttttcga aagttcgttt ttctgattca ctagcatctt
     7741 cataccattt ttttgcttga tcaatggcaa ttgggatcgc acggttatca gggtaccctt
     7801 catctaataa tgcatttgcg atgtcgattg ctttttttct tgtcaattta tctaagtttt
     7861 tcattgatgc aggaaagtcc ttcatgttcc atggcatatt agtatccccc tttattaaaa
     7921 aacataatct atataaacaa gtgtaagggt atttatacaa aaagaaaaag attttgtttg
     7981 agaagtaaaa ccgttgtatt tatcgtcaag tagttttact taacaaaatc gtgaaaaaca
     8041 ctagcaatct agaaaaaatc atggtaagat aatcaagtct gagagtcatc ttagaggatt
     8101 cttgtaaaaa tgggagggaa aaacatgcgc gtaaacatca ctttagagtg tacttcttgt
     8161 aaagaacgta actatctaac aagcaaaaac aaacgtaaca atcctgatcg tttggaaaaa
     8221 caaaaatatt gcccacgcga acgcaaagtt actttgcacc gtgaaacaaa ataatgtttt
     8281 taaagttctc aattccttgc tggtcaaaga attgagactt tttttatctc aaaacatcta
     8341 aaatcataag gagcggataa tatgtttatt tccatgtggg cacaagataa aaatggtctg
     8401 atcggcaaaa atggtttgtt accatggcga ttgccaaatg atatgcgttt ctttcgcgaa
     8461 cacacaatgg atcgaatttt agtgatggga agaaagacct atgaaggaat gggggatctt
     8521 tcacttcctt atcgccatat catcgtgttg acaacgcaac caaattttcg cacgaaagaa
     8581 aatgcggaag taatgcattc gatcgatgaa cttttgtcgt atagtcaaac gatctcagaa
     8641 gatatctatg tttcgggtgg tagtcggatt tttcaagaac ttcttcctta cactggtcgg
     8701 atctggcgaa cattgatcga tagcacgttt gaaggcgata cgtatattgg gaatattgat
     8761 ttttcagact tcgcccttat agaggagtat gaggggataa cggatcaaga aaatctatat
     8821 gcccatcgtt ttcaaaaatg ggaaagagta aaaaataggg ttgcttcaaa agaagaataa
     8881 aatctatgcg tctagtttgt taataagaaa aaaagcatct cacgactaat cgtgaagatg
     8941 ctttttttag ttaaaatcaa tttagttttt ctttgatatc attgaccatt tcctgactgg
     9001 caataggtcc gttatatagc caactagatt caggtccgaa ttgcagtaca tgattgtctg
     9061 tcactgcttt tagattcttc cagcttggtt cattgaacat ggcagcatct ttgtcactgt
     9121 tcacaaggat gatgtagtca gcatctaatt cagctagctt ttcagaggaa acagcagacc
     9181 agtcagaagt ggcttttttg gagacctctt ccactagatc aggaacacca aattccagat
     9241 cgtcgtatac gattcttcca cttgaccgat ttttgctgac cataaaggct gagttgttgg
     9301 tcacccacaa cactgcagct gtcttgttct cgattttatc tgctagttct tctcgagttt
     9361 tcttgatgga tttttgataa tcggaaatga ttttttctgc ctctttttct tttgccaaag
     9421 ctttgccgac atcttttagt tgttcttccc atgtgacatc tgttccgttt tttacaacat
     9481 aagttggcgc gattttgcta tattgttcgt atttcccgcc ttcgacagta gcggaagaag
     9541 aaatcaacag caaatcaggc tcaaagctta acactttctc ataaggaagg tcataagaaa
     9601 tcgttgggac atcctttaaa tcatcttgca gataatcttg aatggaacca ctgccaacag
     9661 tccactgggc gataggtttt tcccctagtg caatcagata gtcttctaag taactgccga
     9721 tgatccgttt gggcgcgttt ggaatctcta ctttatgtcc aagtgtatct gtgactgtat
     9781 gagtactatt ggatgaagtc gtcgaattgg cagttgtagc tgtttcttta tctgaagagg
     9841 gggagcaagc gctcagtact ccagccagca gcaatatgct agataatgtg aatacttttg
     9901 tttttaattt catttctttc ctcctaacat aattgagaat ctttctcatt ggttattatt
     9961 cctgatattt cgaacgctgt caaccgcttc atttggctat agatatgaaa gtagcgcttg
    10021 acgaaatgtt gaaacagcgt cataattgag aatgattttc agcgaaagga tgggtgaaat
    10081 gacgagatta agagcagctg acattgcagc cggctacgaa aacaaaaaaa tcattgaaaa
    10141 catgtctgtt acgattcctg aagggaaaat cactagtttg attgggccaa atggaagtgg
    10201 aaaatctact ttattgaaaa gttttacccg tatactacct gtgaaatcag gaaagatcat
    10261 tgtcaataac tctgatatct ctacatacag ttcaaaagaa cttgcaaaaa aaattgcatt
    10321 attagcacaa actagtgaac accctacagg tatgacagta gaagaagtag tatcttacgg
    10381 acgataccct tatcaaaaac tgttcagtgg catggacacg caagatcatg aagcaattga
    10441 gtgggcgttg gatgctacag gtctagctgg atttcgtatg cgggatatcg caacgctgtc
    10501 tggtggacaa acccagcgtg tctggatcgc tatggcgctt gctcaggaaa cagatatctt
    10561 gatcttggat gaaccgacaa catttttaga tccggcacac caattagaga tcctacagtt
    10621 attgactgaa atcaatcaaa tgaaacaaac aacgatcttg atgtcgattc atgacattaa
    10681 tcatgcttca cgtttttcag attatttatt agcaatgaaa aacggtaagt tgatcacaga
    10741 aggtacacct gaagaagtga tcacaaaaga gtgtatgaaa aaaatatttg agattgatgc
    10801 aacgattgtc acgcttccaa gaacaaataa accagttttt ctaacctatg atttgttgcc
    10861 aaaagagcag gaggatcaat tatgaggact atgaagaaaa atagactcct gcttttggtc
    10921 tgttttgttc ttttgattat tttttttgtt gctctttcaa atggcgcagc gactgtggga
    10981 aaagcagatt tttggcaggc gttgtttgat tttgatagat caaaacaaag tcaccaaatc
    11041 atacgaaata ttcgtttgcc tcgtgtggcg ggagcatttc ttgtagggag ttgttttgca
    11101 ttgagcggtg cattgatgca aggagtgaca agaaatcctt tagcagattc aggcttacta
    11161 ggaatcaacg cgggtgcttc gttggcaatg gcccttagtt ttgctttttg gcctaaagct
    11221 tctgattttt ctgtgtttct aatgtcattg gcaggttctt ttgctgtaac tttgctcgta
    11281 tttggttttt tgcagttttc gaaaatgggc atgaatcctt tacagctgat tttagctggc
    11341 gtagctatta gttctttttt tactgctatc agccaagcac ttacccaatt ctttaatctg
    11401 cagcaggatc ttgctttttg gtttgtaggc ggagctgcca atatcacatg gaaacaatta
    11461 gcagtattgt ttcctttata tatacttgct gttttggttt ctttttcatt aggaaaagca
    11521 atatctttga ttcatttgag tgaaacacat gcattagctc ttggaagtca tcctaaacga
    11581 acgcggttga ttgttttctg tctagttgca gtgttagcag ccattgccgt ttcgttagtc
    11641 ggacctgttt catttattgg gctgttggtt ccgccagttg ttcgcggaat ggttggaacg
    11701 gactatcgtt atgttctacc tgtctctttt ttagttggcg gtggattggt tatgttggcg
    11761 gattttacag cgaggatgat caatccccct tttgaaacac cttttggatt agtcattgca
    11821 ttgattggcg ttccgttttt actgatacaa gtaaggaggg aacaacggtg aaaaaaatat
    11881 attggacgtt ctatttcttg ctttttgtac ttgtcatcct gtctataggt agtttaatga
    11941 ttggtacgcc ttttatttac ctggatcagc tttttgccac gttcataggg aaagaatcat
    12001 cttctttggc gctgattgtt agagaatttc gagttcctcg attactgatc agtttattag
    12061 caggagcttg tcttggcgtt tctggttata tcttgcaagg agtaacaaga aatgaattgg
    12121 cagattctag tatattgggc attaatgccg gagcaggatt tttagtgatg ctttatttag
    12181 gtttcttttc gcactattcg ctgccgtttc tattgctagt tgtagccttt ctaggtggtg
    12241 ttttagctgc ttgctgtgtc tatcttgcgg cctatgatcg aaatggcttt ttgggtatga
    12301 atcgaatctt attgtccggt attgccgtta atgccggcct ttctgcatta acattgctat
    12361 gcacgatcca attatctaag gaaaattatg gatttgtgaa tgcatggtta gcgggatcaa
    12421 tctggggtgc gagctggcct tatgtttggg cattgcttcc atgggcggtt atcttaattc
    12481 cgctaggagg actttatgca cagaggattg tattgctatc atttggtcaa gaacgcgcgc
    12541 aaggattagg ccttaacgtg gctaaaagtc aaaaaatcct tttgttgtta gctgttgctt
    12601 tggcaagcgg tagtgtagcg gtgacaggta gtttatcttt tgtaggacta ctagctcctc
    12661 atgctgcgaa gctagtcgta cgtaaagaaa ataactggac ctttgttctg agcggtttgt
    12721 tcggttccat ttttctgctt agtgcagata tggttgctag agtgattcta ctaagtgggg
    12781 aagtacctac aggaattttg attgcccttt ttggtgcgcc atattttctg tatgcacttt
    12841 ttatcagaca aaaacacgcg ctgaacagtt gaaattcatt aaaaaaggaa ggccaatcat
    12901 ttctaggtct tctttttatt ctatttatgc atttatttga aagttcgatt gctatttttc
    12961 tttttttcct ataccatttt atgagagaag gaagggtgag tttttggacc aattgaaagt
    13021 aagattacgc cggaaaggaa tcgaaaagct gaaaaatctg gccaaaagtg gcaagaaaaa
    13081 ggaaaaagaa cagcgaatct ataaacagct attcgccagc gagtactgga agtcagcaaa
    13141 agtgataggg acgactttat cgaatgaatt tgaactggat acacagccgg ttatccaacg
    13201 agcagaaaaa gaacaaaaga aaatagttgt acctaaaact ttgccgaaac gtcagatggc
    13261 gttttatgaa atggatgaac agtccgttct tgtacgttcg agttttggtg ttcttgagcc
    13321 acaatcagag aagctctatt tgccggagat gatcgatctc ctcattgtac caggtattat
    13381 ctacaataga gccggttatc gaatcggttt tggcggtggt tattacgacc ggtatttaaa
    13441 taattttcat aaaaaaacat gtagccttgt ttttcgtgaa caattgaatg aacaatggca
    13501 accggagagc tttgatcaga agatccaaca attgtttatt gactaaaatg aaatgggagg
    13561 ttttcatgaa ttatcaacag caaataaaat tgcgtgcatg gttaagacga ccgttatgga
    13621 cctatgcttt tttagggata cagacagcgg tcttcctcat gatggaatta tttccgcgac
    13681 ttgagatccc ttattatgcc ggaatgtatg gtccttatct tgttcacttc aatgaatggt
    13741 ggcgtttagt gacaccaatc ttcatccatt ttggactgat gcatttcgta atgaactcac
    13801 tgatactgta ttttatgggg cagcaaatcg aggcaatcta tggccattgg cgttttttct
    13861 tgatttatat gttcagcggg ataatgggaa atacagcaag ctttgctttt aacgaagcga
    13921 atgttctgtc tggtggtgca agtacttcga tattcggttt gttcggtgcg ttgtttatct
    13981 tagggtttca ttttaaacat aacccagcga tccagcagct agtcagacat tttcttttat
    14041 ttattgtgtt gacatttgtt tttggtcttc tggatacctc tgtagatgtt tggggacatg
    14101 tcggtgggct aattggcgga ttagtgttag ggaatgtttt gggtctaccg aaacaacaga
    14161 caagctattc gatacaccaa aggattcttt ctacactagt ttttgtattt ctttttgtaa
    14221 tatgtatttt actgggttta aaaaaatatg gtttacttgt ataatatgaa ggaagtgctt
    14281 aaagatggag agcttatatg atgtacagca gctgttcaaa aaatttggca tctttatcta
    14341 tgtgggtgca cgcatctatg acattgaatt aatgactatc gaattgcgta atctgtatga
    14401 tagccgtttg attgatcatg atacatacat gacagcgtgg cgcatattaa aaagagagca
    14461 ccgaattgaa gaaagccgaa agaaaggaaa tttgtaatgg acaagaagat tattgggatt
    14521 gatttaggtg gaacaacagc aaaatttgca attttaacac cagaaggaga gattcagcaa
    14581 aaatggagca tcgataccaa tattttggat gatggtaagc atatcgttcc tgaaatcatt
    14641 gaatcaatca atcatcgttt gaatttatat aatatgaaag ccgaagactt tatcggaatc
    14701 ggcatgggta ccccaggaag cgtggacagc gaagctggaa cggttattgg tgcgtataac
    14761 ttaaactgga cagaagttca atttgtgaaa aaactgatcg aggcaggaac aggaatcaaa
    14821 ttcgctatcg ataatgacgc gaatgttgct gctttaggtg aacgatggaa aggtgctgga
    14881 gaaaacgatc cagacgttgt attcgttact ctaggaacag gtgttggcgg aggtatcgtt
    14941 gctggcggaa atttgattca cggcgtgagc ggagctggag gagaaatcgg acatatcact
    15001 gtggatcctg aagggttcga atgtacttgc ggtaaacgcg gatgtttaga aactgtatct
    15061 agcgctacag gtgtggtacg cctaggtcgt ttcttggcag aagaatacgc aggggattca
    15121 aaactgaaag caatgctaga caacggagaa gaagtaacaa gtaaagatat ctttgaaatg
    15181 gctcaagaag acgatccgtt tgcattgatg gttgttgatc gcgtatgctt ctacttaggt
    15241 ttagcttgcg gaaacttggg gaatacatta aatccgtcaa gtatcgtgtt aggtggagga
    15301 gtatcggcag caggagaatt tttacgtagc cgtgtagaga aatattttaa agaatttact
    15361 ttcccgcaag taagagaatc aacaaaaatc aaattagcag agcttggtaa tgaagctggt
    15421 gtcattggtg ctgcctcatt agccttgaaa tttgcttaaa aaaacggagg cattacatgg
    15481 ttttatgggt aattaatatc attttgctat tgattgtgct tgcaatcatc ctttgggaag
    15541 tctatctacg agtaatggcc aaacgttcag caacgacttt gacagaagaa gaatttcgag
    15601 aaggaatgag aaaagcacaa gtaatcgatg ttcgcgaaaa agatgtgttt gatgctgggc
    15661 atattttagg tgcaagaaac atcccttaca ctgttttgaa agattcatta ggatctattc
    15721 gaaaagacca gcctgtctat atttacgatc aaaagaaaag tttgagcatc cgtacagcaa
    15781 ataaattacg taaagcaggt tatcaagaga tttatttact taagggtgga tatgacggat
    15841 ggtctggaaa aatcaaaagt aaaaaagtat aaaacagatg attgtatgac agctttaaaa
    15901 accgaatcaa tcattagatt ttgaccaaga tcacatgaac ggcgcaatgg atagttgtgc
    15961 cgttcatttt ttttattttg tgctattatc tacatatata agctaagcga aaaggtagaa
    16021 agaaggaaac aactatgatc aaattaaaac gtgtttacct tgatgctgaa aaagaggatg
    16081 gctatagaat actcgtggat agattctggc cacgaggaat ttcaaaagaa aaagcgcagt
    16141 tagatctgtg gttgaaagaa attgcaccta gtaatgaagc acgcaaaact tttgaccatg
    16201 taccagaacg atttgcttca tttgcaaaga aataccagca agaattgatt ttcgaagaag
    16261 aaaagaagca agctattttt aaactcagtc aacttatgaa agaacatcca gtcattactt
    16321 ttgtttatgg tgcaaaaaat gaacatcaga accatgctgt tttattgaaa aaatttatcg
    16381 aaatggaggc atgcaaatga aaatagggat cattggtgcc ggacctagag gattaagtgt
    16441 agcagaaagg attctccata ataatcagga cagacattct cttgaacttt ttcttttcga
    16501 tcccaatggt cctggaggtc gagtttggcg gttgaatcag ccaccggagt tattaatgaa
    16561 ttctgtttct caacaagtga cgctttttac agatgaaaca ttgtccagtg gaggattggt
    16621 aacacaggga cccaacttgt ttcaatggag taaaggacct gctacagatt atatcgaaca
    16681 gacggtaacc aaaaataagc aactaattat agaagaaatc aatcgtctgg aaaaagatca
    16741 gcaatctact cgatgtttat acggactcta tcaacgctgg tttttctcaa agttgcaaga
    16801 agaatttcca gcttctattc agtttgttta ttctttagta aaaaaagtaa gcaaaagaaa
    16861 agatggttat cttttacaga cagatcagca aagctattct atcgatcagc ttgttttagc
    16921 aagcggtcac tgggaaaatg atgagacaga agaagaaaga gtgtgggtag actacgcaaa
    16981 gaaaaatgtt ttactgtatc agcttccttc taatcctgca gatgtagatc tttcgaagat
    17041 accgcctaaa gaaaatgtct ttttaagagg tctaggctta agtttttttg attatgtcgg
    17101 attgtttaca gtatcaagag gagggcgctt cgagaacgaa aagggaaaac tggtctatca
    17161 tccatcaggc aaggaaccga ttgtatacag tggatcaaga agggggctcc cttattaccc
    17221 tcgaggaaga aatcaaaagc aaggcggagc aatggcatgg ccacggttac taacaaaaga
    17281 aaacctggag caatggcatc agtcgggatt tttgactggc gaaacatttt ttgactatct
    17341 gaaaaaagac gttgagttgt tttattacaa gaaaatcatc gaagaatatc acttgccgat
    17401 tccaaagaaa aattttgagc atgattttct ctccctctct tcagaggagt gtctcggaaa
    17461 gcatccagca ctaatccctt atagatggga ttggtcgtat ttagaaactc ctcttgccta
    17521 tcagaatgag cccttttcag aagctagccg aatatttatt gaagggcaga taaaagaagc
    17581 ggaaaaaggc aattgcacag gagcatttgc ttcaacattt gatgcattaa aagactggcg
    17641 tgatccaatc cggcaggcta ttgaatggca cgttttttct gctaaggaat acaaagaaat
    17701 actatgggga tggtttactc atctaaatag ctttttaacg atcggtccgc caatcattcg
    17761 gacgaaagaa ttagcagcac tgatagatgc gggtattttt catttgatcg aaccgccatt
    17821 tgatattcag caaaagcaca accgctatgt tatttctcta caagataaag aaatcagcag
    17881 tcgctatttg attgaagctc gattgccaca aacaagcttt tctcgttcaa gtaatcctgt
    17941 cataaaaaat ttgaaggaaa acaaacttgt tcgccctttt tcattttcag ataatacagg
    18001 aagttatcat tcagaagcta tagatgttga gcgaggtacg aatcgcgtga ttgatgcttc
    18061 aggggaaatc cagtctgact tttattgcta tggaatacct gttgaaggtg tggattggct
    18121 aactgcagca gtagctagac cttatacaga tccatggaat ctgagacagg cagataaaat
    18181 agcacaactt atattgactg acaaataaaa atacgcatga tgacttatct gttttttaga
    18241 aagtcttcat gcgtattttt aaataattat taacgagaaa cgcgtttacg cattgctttt
    18301 ttacggtttt cttcgatcat tgcttctttt tcgtcaattg gatcgatcac tgtttttttc
    18361 acagaagcaa ccaaaccagc aacggcagcg gctgttgcca gacttcctac taatattcca
    18421 gatacaaatt ttttcattga atccacctca tttattattt gttatatcta ttatggaaca
    18481 aaagagaaaa aaaggctagt tttacgtttg tttgtaaacc tttgcaaaaa atccttgaaa
    18541 atgtttacta aatgttttat tataaattta ccatatgaat ttacgaaatt ttactttgtt
    18601 tgttttcacc ataaaagtaa acttcgtttt ttaaattata tagaatcaac aaacacaatt
    18661 ttactaatca aaggagtgtt ttttatgaca attttagtac taggcggagc cggttatatc
    18721 ggttcgcacg ctgtagacca gctagttcaa aaggggtatc aagtagctgt ggtagataat
    18781 ttgctcacag gtcacaaaca agcagtacat ccagatgctc atttttatga aggagacatc
    18841 cgggataaag aatttctacg ttccgtattt gaaaaggaac cgattgaagg agtaatccat
    18901 tttgctgcaa gctctttagt aggagaatct gtcgaaaaac cattgatgta tttcaacaac
    18961 aacgtatacg gtatgcaaat cttacttgaa gtcatgcacg agttcaacgt gaataaaatc
    19021 gtattctctt ctactgcagc aacttatgga gagccgaaag agtctccaat cacagaagat
    19081 acaccagcta atcctaaaaa tccgtatggt gaaagtaaat tgatgatgga aaaaatgatg
    19141 aagtggtgtg accaagcata tggcatgcgc tatgtcgctt tgcgctactt caatgtagcc
    19201 ggagcaaaag cagatgcatc tatcggagaa gatcatacac cagaaacgca tcttgtccca
    19261 atcattttac aagtagctct tggtcaaaga aaagccttgg ctgtttatgg agacgattat
    19321 gatacaccag atggaacatg tatcagagat tatgttcaag tagaagattt gattgctgca
    19381 catattttag ctttggaata cttgaaagaa ggaaatgaaa gcaacttctt caatttaggc
    19441 agcagcaaag gatactcagt caaggaaatg ctagaagcag ctagagaagt gacaggaaaa
    19501 gaaattccag cagaaatagc accaagaaga gctggagatc ctagccgatt agtcgcttca
    19561 agtgaaaaag cgagagagat tctgggctgg aaacctgaat acacagatat caaagcgatt
    19621 atcaaaacag catgggattg gcatgtcagc catccaaatg gttatgaaga ataggggaat
    19681 gagatatgtc aatcagtcaa acgatttgtg attttgccac acttgcgatc gaagctggcg
    19741 gatggatgga aatggaccgc ttatatttac agaatcgtct tttagggatg gtaggagaag
    19801 atgctctaga aagcattgaa gtaagaccag ttaaggaaga atctgtagac ttattggatc
    19861 agcttgtcgc taaggcaaga gaaaatggtg ttctttcaga attgccagca gaacaagaga
    19921 tttttgaagc gcaattaatg gattttctca caccgccacc ttcagtcgtc aatgcattct
    19981 ttgcacagca ctattcgaaa agcccagagg aagcaactga gtatttcttt aatttaagta
    20041 agaaaaatga ctacatcaaa acaagagcca tcgcaaaaaa catcaaattt ccggcagagt
    20101 cggagtatgg tgaactggaa atcacaatca atttatctaa gccagaaaaa gatccaaaac
    20161 aaatcgcagc agaacgcgag gcggtaaaag tagactatcc tacctgcatg ctttgcatgg
    20221 aaaacgaagg atatagaggt cgcttgaact atccagcccg caccaatcac cggattattc
    20281 gaatgaatct agacggtgaa agctggggat tccaatattc cccttatgct tattacaatg
    20341 aacattcgat cattttatca gaacaacacc gcccgatgaa aatcacaaag gaaacatttg
    20401 ctagactgct tcggattact gaagtcttgc ctcattactt tgttggttcg aatgctgact
    20461 taccaattgt tggaggatcg attctttctc atgatcatta tcaggcagga cgtcatgaat
    20521 ttcctatggc aaaagcaccg atagaaaaac ttatcaaact agaagattat ccgcaagtca
    20581 tcgcaggagt cgtgaaatgg ccgatgtctg tgatccgttt gcaatcaaca gagaaaaact
    20641 tgcttattga agcagctaac tcagtattgg aaaaatggaa agcatattcg gatgaaacag
    20701 tatctatcag agctttttca gcagatggta caccacacca tacgattacg ccaattgcac
    20761 gaagaaggga caattacttt gagttggacc ttgtccttcg agacaacaat gtttcagaag
    20821 aacatcctga tgggattttt catccacata aagatgtcca acatatcaaa aaggagaaca
    20881 ttgggttgat cgaagtaatg gggcttgctg ttttaccacc tcgtttgaaa ccagaactag
    20941 tagaagtaga gcatttctta ttaggagaag aaaaccagat ggctgaatat catcgtccgt
    21001 gggcagaaca attaaaaaaa gaacatcctg atttgacgaa agatacggtc accgatgtcg
    21061 tacaaaaatc tgtaggtcag gtttttgcac gtgtactgga agacgctgga gtattcaagc
    21121 gagatgaaaa aggacaggca gcgtttgaac gatttactgc gattttataa acgtaaaaaa
    21181 ggaggagaga caaatggcaa caattaaaga cattgcgcag ttggcaggag tttctcctgc
    21241 tactgtttca agagttctca actatgatcc tgatctttcc gttggcttag ccacaaagca
    21301 aaaaattttt gaagcagcag aacgcttaaa ttatacgaaa catcgtaaaa atgcagcaaa
    21361 tactaagcaa acgcttcgcc tgatccagtg gtacgacgat acggaagagc ttgaagatct
    21421 ttattattta tctattcgcc taggaatcga aaaaaaggca gaagaagcaa acgttacttt
    21481 attgaaagaa acgtgggatt ccattagtga tcttccggca gatggaacga tcgcactagg
    21541 aaaattcgac gaagctcagt tattagaaat gaaaggatcc caaaatgcct tgcttttggt
    21601 agattctgac ggcacttctc aaggaatcga ctctctagtt gtcgacttta agtcaagtgt
    21661 tcaaaaagtc attgaacact ttgtctccca taaagcgcaa catatcgcta tgcttgctgg
    21721 aacagaatat acgaagaaaa accatcagcg gctaaaagat cccagaatta tggcatttca
    21781 acaagttttg gcagaaaaag gctacgacga aggtccaatt atcgaagcag atttttctgt
    21841 cgagtcagga tatcaagcag tgaagcagta tttaaaaacg aatccgcatg ttcctgatgc
    21901 gctttttgca gctaatgatg cattagcgat tggcgcactg aaagcgattc aagaaaaagg
    21961 tttagtggta ccagaagata tttctgtgat gggcttcaat gatgtcagtg tagcgaaata
    22021 tgtaacgccc tcgctttcta ctgtaaaagt ttataccgaa tggatgggag agctagcagt
    22081 ggagacgatt cttcaattaa gtaattccaa agcaccggtt tcaagaaaga ttattgtgga
    22141 aacagagttg attattcgag aatcaacgaa ataaaagatg gaaaagctgt gggaaaatgg
    22201 agtgataccg cagctttt
//
LOCUS       DAFBSV010000047        21832 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.048, whole genome shotgun sequence.
ACCESSION   DAFBSV010000047 DAFBSV010000000
VERSION     DAFBSV010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21832
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.048"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(26..1522)
                     /gene="lysS"
                     /locus_tag="LLB18_001641"
     CDS             complement(26..1522)
                     /gene="lysS"
                     /locus_tag="LLB18_001641"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBK5244643.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="LLB18_001642"
     CDS             complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="LLB18_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBK5244644.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="LLB18_001643"
     CDS             complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="LLB18_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBK5244645.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3742..5853)
                     /gene="ftsH"
                     /locus_tag="LLB18_001644"
     CDS             complement(3742..5853)
                     /gene="ftsH"
                     /locus_tag="LLB18_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBK5244646.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="LLB18_001645"
     CDS             complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="LLB18_001645"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBK5244647.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="LLB18_001646"
     CDS             complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="LLB18_001646"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBK5244648.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8053..8523)
                     /locus_tag="LLB18_001647"
     CDS             complement(8053..8523)
                     /locus_tag="LLB18_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HBK5244649.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8569..8994)
                     /locus_tag="LLB18_001648"
     CDS             complement(8569..8994)
                     /locus_tag="LLB18_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBK5244650.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9061..9330)
                     /locus_tag="LLB18_001649"
     CDS             complement(9061..9330)
                     /locus_tag="LLB18_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBK5244651.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9341..10936)
                     /locus_tag="LLB18_001650"
     CDS             complement(9341..10936)
                     /locus_tag="LLB18_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBK5244652.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="LLB18_001651"
     CDS             complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="LLB18_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBK5244653.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14489..15049)
                     /locus_tag="LLB18_001652"
     CDS             complement(14489..15049)
                     /locus_tag="LLB18_001652"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBK5244654.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15402..16376
                     /locus_tag="LLB18_001653"
     CDS             15402..16376
                     /locus_tag="LLB18_001653"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBK5244655.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16546..17946
                     /locus_tag="LLB18_001654"
     CDS             16546..17946
                     /locus_tag="LLB18_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBK5244656.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18024..18746)
                     /locus_tag="LLB18_001655"
     CDS             complement(18024..18746)
                     /locus_tag="LLB18_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5244657.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18825..19331)
                     /locus_tag="LLB18_001656"
     CDS             complement(18825..19331)
                     /locus_tag="LLB18_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBK5244658.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19454..21253
                     /locus_tag="LLB18_001657"
     CDS             19454..21253
                     /locus_tag="LLB18_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBK5244659.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21321..>21832)
                     /locus_tag="LLB18_001658"
     CDS             complement(21321..>21832)
                     /locus_tag="LLB18_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBK5244660.1"
                     /translation="TEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTPEQPKPVT
                     PAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTGRDIGGWT
                     VPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESVKVGSVQW
                     FAPDFAVSM"
BASE COUNT         6048 a         4789 c         3964 g         7031 t
ORIGIN      
        1 aattccttag acagctttta ttcgattatc tcattgttgg gaatagcaaa acatcccgaa
       61 ttgattgtgc atcagttagc aacattacta atctgtcgat cccgatgcct agaccaccag
      121 ttggcggcat accgtattct aaggcttcca agaagtcttc gtctacaccg tgagcttcgt
      181 catttcctag ttcacgttct ttttcttgcg cttcgaatct ttctctttga tcaattggat
      241 cgttcagttc tgtaaaggca ttagcaaatt cgcgccccac tatgaatagt tcgaatcgat
      301 ctgtgaatcg aggatcttct ggatttttct tcgctaaagg cgaaacttcg actggatgtc
      361 cgtatacaaa cgtcggttgt gtcaatgttt cttcaacaaa tgtttcaaag aattcattga
      421 taacatgtcc gacacccata gcttcggtta cttctacatt gtgtttttcg gctaaagcta
      481 atgcttcttc caatgtcatt tcttgccaga agtctacacc agtttgttct ttgattgcat
      541 ctaccatatg gatgcgttta aagtcacttt ctaagtcgac agcttgtcca tcatatgtga
      601 tttttgctgt tcctagtact ttttcagctg cgttacggat aataccttct gtcagattca
      661 ttacatcatt gaaatcagta tatgctgtgt atgcttctaa catcgtaaat tctggattat
      721 gtgtagtatc aattccttca ttacggaaaa cgcggccgat ttcataaact ttttccattc
      781 cgccaacaat tagtcgtttt aaatgaagtt ctagcgcaat acgcaaatat aaatcaatgt
      841 ccagtgcatt atgatgcgtg ataaatgggc gtgcggcagc tccacctgcc tcattgtgca
      901 atactggtgt ttctacttca atatagccat tgccatctaa atagcgacgg atttcgctga
      961 taatttggct tcgtttcata aatcggtcaa agctttcgcg attactgatt aaatccaagt
     1021 agcgttgtct gtagcgttgt tcaatattcg ttaagccatg gtatttatct ggcagtggac
     1081 gaagtgcttt tgacaaaatc gtgatttctg aagctttgat agaaacttcg cctgtgtctg
     1141 ttttcatgat ttgtccagtt acaccaaaga aatctccaag gtctgcatgt ttgaatactt
     1201 cataggcctc atcacctact tggtcttttc ttacataaat ttgaatttgg ccttcacgat
     1261 cttgtagatg cgcaaatcca gttttccctt ttcctcggcg agtcatcata cgaccagcta
     1321 cactagcggt caatcccatt tctgctagtt cttcttttgt tcttggatca aatagttcat
     1381 gcaattcttc tgagttgtgc gtgcgttcaa atcgttttcc aaatggatcg attccatctt
     1441 cacgcaattg ttccattttt tgacgacgta caagcatttg atcatttaaa tcttctactt
     1501 gatgttgttg ttcctgtgtc acaaaagttc ctccattctc atgttaatct ctttcctata
     1561 atgccaatga aacacaaaaa aagcaagccg aacttggaat ttcggcttga aaattcacga
     1621 aaaacttaga aatcacaacg tttgtttcaa tagtactttt tccgcttttt ctacaaattg
     1681 atccagcagg tcattgattt cttgctgttt ttctgtctga ttgattgcta ctttcacttt
     1741 cgctgctcga ggaatccctt ttaaataata agccgcatgt gttctgaatt ctctacaagc
     1801 tactttttct cctttgagat ctgctaagcg ttgtaaatga agtttagctg tagcaatttt
     1861 ttcggctggt gttggttcag gaatcagttc tcctgtttcg agataatgct gtgtgcggtg
     1921 aatcatccat ggattgccca gcgctgcacg accaatcatc acaccgtctg caccgacata
     1981 gtcaagcatc cattttgcat cttctggcgt tttgacatcc ccgttcccca taaatgggat
     2041 cgtcaaatgt tttttcactt ctttcaatac ttcccagtcc gcttttcctt catacatctg
     2101 aacccgtgta cgtccatgca tagcgatggc acttgctcca gctgattgtg ctgctaatgc
     2161 attttctaca gcaaagacgt gctcttcatc ccaaccaata cgcatcttga ttgttactgg
     2221 gatatttact gctgaagaaa cagcttggac catttcgtat actttctcag gatctaaaag
     2281 ccattttgct cctgcttctg ctttgattac tttatttact ggacagccca tattgatatc
     2341 tattatatcg gcagctgtgt tttcttcgac aaattgagca gcttcaacta gactatcttt
     2401 atttccgcca aatatctgta aacttaatgg atgttctgtt tcttcaatgt ggagcatctc
     2461 taaagttttt ttgtttctga aatgaatacc ttggtcactg atcatttcac atacgactaa
     2521 gcccgcacca aattctttga cagtgactcg aaatgctgaa tttgttattc cagccatcgg
     2581 tgcaacaacg acacgattag ggatttccac attgccaatt ttccatgtgt gttccactta
     2641 aatccctcct aaggcttctt tcttcaatcc atctaattct tcttcgctat acttgtattt
     2701 gttattacag aaagaacaaa ccgcttctgc accgtgatct tcgtctatca ttgcttggat
     2761 ttcttctgca cctaacgcga taattgcttc tgcaaatttt tcttttgaac agtcacattt
     2821 gaattgaaca ggcatttttt ccaaaatgtt caattcttct gtaccaagca atcctttcaa
     2881 tatttcttct ggtgtctgtc cttcatctaa gagggtagag attcttggtg tcgtttttaa
     2941 ttgttcttcg atcttgctga ttgtttcttc atcggcacct ggcatgattt ggatcatgaa
     3001 tcctcccgcc gtcttgatgc tgtcgtcagt attgaccaat acactcagtc caacagctga
     3061 agggatttgt tctgagatag caagatagta agtaaaatct tcagcgattt ctccagaaac
     3121 aatcggcgtt tgcccagaaa aaggttcttt taatcctaag tcttttgtga cagtaaacat
     3181 tccttgtgtt ccaactgctc cccgcacatc gattttacct tcactattta gaggaagact
     3241 gagatgcgga tttttgatgt aacctttcac atctcccttt ccatttgcat ctactacaat
     3301 tcctgttgct ggaccatcgc cttggattcg aacagttagt ttgtcttctc ctttgagcgt
     3361 cgcaccaagt agcagactac cgaccaatgt ccgtcccaaa gcagctgagg aggtgtgcca
     3421 agtatcatga cgtctttgtg cctccgctac ggtatttgtt gcttgaacgg cgtatgctcg
     3481 gacgaatccg tcgtgagcaa gtgccttaac caaataatct ttcatttgtt atgtactcct
     3541 ttttccgttt ttaaactcat agtgaatcat actagcaact actgcttttt tcaactttgg
     3601 aatgcttctt ttaaaaataa ttcagaatca tctagaaaac aggacatcac cctatttaca
     3661 acttaaataa agaaatctcc cgaaaaccgg tttttgttcc ggttttcggg agtcatatca
     3721 gatcaattga cctatatttt tttatttgta ttgatcgtct gaatgattat cttctgattg
     3781 ttgagaatct gaatcatgtt ctgctttatt ttcctcattc agttcatgtt ttgcttcttc
     3841 aaaatcacgt ttttcttccg cttgtttttc agcgtctttt tcttccaaag cacgttttgc
     3901 ttcttcaaaa gttttcgctt ctttttcgct tggataatca tttgactcag taccttcagg
     3961 catcacaccg tgttcaaaca atgacttgat tgctttggca tccaatgttt cgaattccaa
     4021 aagtttttca gcaatcagtt tatgctgtgc acgatgagct tcgatgattt ctcgagcttt
     4081 atcatgagct tccatcaaga tttttcgtac ttcttgatca atctcgaaag cgacttgttc
     4141 cgagtaagct tttgtttgac catagtcgcg gccaacaaac acttgatggt ttccttcata
     4201 ttgaacagga cctaaacgat cactcattcc atattctgtt accatgcttc gtgctagagc
     4261 tgtcgcttgc tcaaagtcat tggaagcacc agttgattgg acattgaaga tgatttcttc
     4321 agctgtacgt ccaccaagta agcctacgat ttgttcaaac atatcttctt tcgtcatcaa
     4381 gaactgatct tcttttggta aagcgatcat atatccgccg gcgcgtccgc gagggatgat
     4441 cgttactttg tggacgaccc gagcgcgact caatactaat ccgacaatcg tatgaccagc
     4501 ttcgtgataa gcaaccattt cgcgttcttt tttgctgatt acgcgatctt ttttagctgg
     4561 acctgcaatc acgcgatctt ccgcttcatc gatatcagaa gcatcgattt tctttttatt
     4621 tcttctagca gctactaacg ctgcttcatt caagacattt tctaaatctg ctccggcaaa
     4681 acctggtgtc tgttgagcca caactttcaa gtcaacgtca tctgccatcg gtttattccg
     4741 tgcatggact cgcaagattg cttcacgacc ttttacatct ggacgtccaa ctaaaatctg
     4801 gcggtcaaaa cggcctggac gtagtaacgc tgggtctagt acatcagaac ggttggttgc
     4861 agcaatgacg attactcctt catttccgtc gaagccatcc atttctacaa gcaattggtt
     4921 caatgtttgt tcgcgttcat catgtccgcc gcccataccg gcaccacgtt gacgacctac
     4981 cgcatcaatt tcatcaatga aaatgatagc tggtgcgttt ttcttcgctg tttcaaacaa
     5041 atcacgaaca cgacttgctc caacaccgac aaacatttct acgaaatcag aacccgagat
     5101 cgagtaaaac ggtactccag cttctccggc aacagctttt gctaataagg ttttacctgt
     5161 tcctggaggt ccttctaaaa gtacacctgc cgggatacgg gcacctaatt caacaaatcg
     5221 gcgaggatct ttcagaaatt caacaacttc aactagttct tgtttttctt cttccgcacc
     5281 cgctacatca gaaaaacgta cgcgattagc ttttttgtct gcttctttgg cttttgattt
     5341 accaaagttc atgacacggc cgccaccgcc accgccgccg ccttgttgtc ccatcatcat
     5401 gtaaaagaaa aagatgatga ttacgattgg caagaagcta agcaataggg aaacccatat
     5461 accgctgctt gattcttctt ttactgttgt agcaactttg ttttcttttg ccagttctgt
     5521 tacttggctc aatgttgtat catttggcaa aatgattgtt gtgaaatggg tagtagtcgt
     5581 atctgttgaa cctaagatag ctaacccacc gctgttagcg acggtctgct gttctttgta
     5641 ttcaccagtg atcttatata caccatttgc aggctgcact tcaaattctt tgatcttgcc
     5701 tgcttgtagt tgttctgtga attttgagta ctcgatatct gacgatcgct ggccgttatt
     5761 accaaaaatg aaataaacga ccattaccat cgctaagatt acgaggacat aatacaaggc
     5821 atttttcatc atgccgttgt tctttttgtt catagttgcc ctccctaagc gtcaatttaa
     5881 tttaacagtt ttttatcaat cctgaccatt ctattgtacc ataatttaat tgagatacag
     5941 cattaatttg attgataaac actaggtttc aatacaccga tgtacggaag gttacgatat
     6001 gcttctgcat aatccaagcc ataaccgacc acaaattcat ttggtacgtt gaagccaaca
     6061 taatctgctt cgatatttac tactcttcct tcaggtttgt caagtagtgt aacaattttg
     6121 actgattttg ctttgcggta tttgaaaaga tccactaaat aagcaagtgt tcttccgctg
     6181 tcaatgatat cttcaacgat caacagatcg cgaccttcta cattcgtatc taagtctttg
     6241 acgattttta cttcccctga cgagactgtt gcattcccgt agcttgaaac atccatgaaa
     6301 tccaattcca aatacgtatc gatagaacga acgatatctg ccatgaatgg taccgctcct
     6361 tttaagacac ctactactag gggattggtg ttttggtaaa tttctgttaa ctctttgcct
     6421 agttctttgc aacgaacttg tatctcttct tgtgagatca aaattctctc aatatccttt
     6481 tccaacatca ggttctcctt ccaattgctt ctttttgata tttgtaaaga agtatgtagt
     6541 gtattttatc agtttcttca cgaatactca aatatgaaaa ggcaaaaggt atcaagctat
     6601 atatatttct tttggcatct gtaatgatcc aagcatgctg cctttgtgaa ttaggtactt
     6661 tctgatcgat aaaatatcta gatacttttt ttgtgagatt ctctgttaat ttaatgcggt
     6721 ctcctgcttt tcttttttcg acatacagtt gcacatcagc aggaatccaa atgtcatgag
     6781 aaaatagaga ccatgaatct gttgctttga tgtcccctgc attttcaggt ttgaccagac
     6841 caatccattc tgtttcattc aaatatattc cttgttctgg aatcagcaac aagcgctggt
     6901 cttctgtctg gctagttgct tgtttttctt ttttagagag tacaacaaaa tgatactctc
     6961 ttttcagtat ccaattattg ccaatactga gttgccattg gctttttttc tgttgccact
     7021 ggtctaaaat cgactccatt tgttgttctt tcaaaataat tcctgttttt gagaatgctt
     7081 tgtcgaaaaa ggagtaaaaa aaatagtatc gttcagcatc tgtcatttct tcaatcattt
     7141 ctgcagaaaa tcgaaattgt tcctcccact gttcgacttc cttttcgatc aactgtccca
     7201 tatatttttg aatgacttgg tctgcccatt ggatctgttg cgaaaattgc tggaaatgtc
     7261 tcaacgcctg tgtattttct tgtttcaatt gaggaactac caaatgacga agccgatttc
     7321 tctggatatc taacaattgg tttgtctgat cctcaaagta aacaagctgc gattccgctg
     7381 cataagtata taggtcttct ttgctaaaac tcagcaacgg acgaatcagt ctgcccgtag
     7441 caaatggttg tacttctttg attccagaaa aagtatttaa ctgtccccca cgaacgattt
     7501 tcattaacac cgtctcgatt tgatcatctc cgtgatgagc agtcatcaac gtgtcatatt
     7561 gtccttcttc catcacgcga gtgaattctt gataacgaaa gttacgagct tctgtttcta
     7621 tggcggattt ggctggatct tcccaaatac ttacatataa agggagattc ttctcttcac
     7681 aatatgagcg aagataggca gcttcttctg ctgattcttc tcttaattgg tgattgatgt
     7741 ggacgatacc taaagaaaaa ccgatttggc gttgcacttg taaaagtaaa tggagcaaaa
     7801 ccatcgaatc aacaccacct gataccgctg ctaaaattct cgatccttgt tgccagaatc
     7861 cttgttcatt cccgtgccga ataaatgact gctgtaatag cggtgctttt ttcccgcctt
     7921 tttcaacgtt catcctttcc acaccctttc ttcctaaaaa aaagagagcg ggaaaacgtc
     7981 taaaacgaca attaacctgc cctctgttga tactatgacc caaatagtcg cactatcatt
     8041 atttgcggct ttttagctgc gacgtccgcc acggccaccg cgctttcctt ctgtgtttcg
     8101 cttcaatgaa gataagcggt catcgctatc tttcaaaaat gaactcatca atgaatcgaa
     8161 gtcttctttt tgagctgaag gttgactgcg agaaaaagat tttttctgtg ctggacgatt
     8221 tcggttgtca cggggatctt tttgttgata ttttttagga cggctttctt ctccagattc
     8281 agcaggttgt tcctgcgctt tccggataga tagtccgatt tttccatcat catttactga
     8341 aataacttta actgttactt catctcctac acttaaaaca tcatggatgt cttttacata
     8401 gccatttgac acttcgctaa tatgaactag acccgttttt ccagcaccta gatcaataaa
     8461 cgcaccaaaa tttgtgattc ctgatacttt tccttgcagt tttgctccta cctcgattga
     8521 cataaaaaaa atgttcctcc taattatttc ccttttttat attcctgctt attttgcagt
     8581 tgtagaacta gttgattgat ctgtttcatt tgtcgagctg tctgtatttg attctaatat
     8641 aggataaact ttttcaccgt cttttgagta aaagaatttg cttctggcaa gtttagctac
     8701 atactcatca tctttcagca atgaaacatc ttggtgcagc tgatcaacgt ctgcgttgac
     8761 ttctttcatt tcagtatttg cttcgactct caattcgttc aattgatgca tcctttgcat
     8821 gtcatggaaa atctgcacac ctattatcgc gaaaatgacc aaagcaccaa caaaaattgc
     8881 agccagtctg cgtcttcgaa aaatcagttg acgttgttgt tgctgaaatt cagcatactt
     8941 tttctttgca tattccgtat ctagcgcagc gattttattg ctttttttcg tcacttggat
     9001 tcgctccaat ctttttgatt gtctttttca ttataccaat atcgtgaaag cttgtctaat
     9061 ctatttctct agtgtttctg tgcgattttc agaaataatt tcgtacattt tttgtgcatc
     9121 ttcttttttg gttgattcat gtaattccgt aattttcact tccaacgttt tgttgccaaa
     9181 ctggactttc aaaatatcgc ctactttgac atcactggaa gatttcgcca atttaccgtt
     9241 gatttgaatt cttcctttat cagctacttc ttttgctact gatcgtcttt tgatgattcg
     9301 ggaaattttt aaaaatttat ctaatcgcat atcttattcc tcacttttta atttttttat
     9361 ttaatcgcag gattttctta ccaaaaggca acattagcca ttctcgtact gtaaacagac
     9421 gaagacgaat cactgcataa atgaacacag aagccccgat cccaactcct atcacgctga
     9481 caaaaaaagc agtggaacga tgagttacag gaccaaatac tatattcaat acaccataat
     9541 acagcagcag tactactgtc atacaaagaa ggctgaacat caacttccgt ccaaaatgcc
     9601 gttctttcca aaaagcattt agctcttttg tttcaattcg aacaaaatac caaagcgtca
     9661 cacctaatcc taaaagggta gacaggcttg cacctgctgt tcctaataaa ccggtcagaa
     9721 aagaagtagt caatcctttt accaatagtc cccatcctgc gccttttaaa gaagggcgaa
     9781 acgagttctt gctttgagca atactttgat aagcttggat gactgcagtg aaagcaatgg
     9841 aaaaaacaaa taatacaagc gctgcatttc ccgcataatc tttaaacaac gcataattga
     9901 tataagggag cagcaaggct aatcccaaag acgcagctaa tgctaaagcg gtcgtcaatc
     9961 taagatagat tttggctgtc tgtaaaaact gacgatagat ccggttggtc aaatgacgag
    10021 tcaacgcagg caggaatgtc gcacttaatg cagtggcaat cactaaacct aattgtacta
    10081 aaggctgacc tcgatcatag accccttttg ctatcttcgc accgtattct gacagtccgt
    10141 aaacttccaa agcatttttt acaaagaaag agtcgatcag ctggaaaaag ataagcaatc
    10201 cactataaat cgaaaccagt ccgccttcta ccagaaaacg ccggatcaag ggctttgacg
    10261 gctgtttgaa caatggaaac cgtcggaagc ttaacgctcc tccatgaatc ttttgttcat
    10321 agtagtgaag gatcccatat gcgcataaac cgccaaaaac agctccactc attgctgccg
    10381 tccctgtttg gtacaccgtc catccaagct ttctaaaagc aaacgcacta cagacaatca
    10441 caaaaacacg aacgaactgc tcaactactt gagaaacagc agttggttcc atcaagaatc
    10501 ttccttggaa attccctcga taaaaagata gaccaggcat cagcaaaaag gtaaaggaaa
    10561 ctacttggat cagcggtttc aattgtatgt ctcccatcat ccaagcaatc cagctgctaa
    10621 atgcaaagac aaacaaccac aaaaagacac ctgtccaaaa tactaaggga taaagatttt
    10681 gcaaagcttg ctttcgctcg aaaggattct ttctttctgc aacgtacttt gatatgaact
    10741 gcggaagacc ggataaagct aaagtcattg ctatcccata aattggataa acttgctgat
    10801 aaacataaaa accttcgtcg ccgactaagt tttggagggg aattcggtaa agggcactta
    10861 atacttttgc tatgaaagaa gcaatcgtca atacaaatgc tccttgcatg acgcgccgca
    10921 tttctttatg atccaaatca ttgctccttc ctacgctgac agatattttt gctcacgcaa
    10981 cgctttgaca aacttttgga tttcctgaag ccatactgct tcttccattt ggttggggat
    11041 cgtcaagcgt atcaccatct gttctttttc aacgcctaga ctggctttta gttttgtcgc
    11101 tgtcagtgct tcgaataact gttccacact atagcgtttt gttccaactt tacttagagt
    11161 aaagactata tgcgcctcct gtttccttat cgtttctagg agcgctcgat cgccatccat
    11221 tttgatctgc ccaattgtca agagatgtgc tacttcttct ggatattctc caaaacggtc
    11281 gagcagatca tcttctagtt catctagcat ttcttgcgaa tcaagttcac gaattcgttt
    11341 atagatctcg attttctgcc gttgatctgc cacgtatgtt tcaggtagat acgcatcgac
    11401 accgaggtcg atctcaacag tggtcttctc cacttgacta ttctttcctt gtttacgaga
    11461 aacagcttcg cttagcattt gagaatacat atcgaaaccg actgcatcaa taaatccatg
    11521 ctgctgagca cctaagagat tacctgcacc gcgaatggaa agatcccgca tcgcaatctt
    11581 gaatccagat cccagttctg taaaatcttt gattgcctga agacgttttt cactgacttc
    11641 gttaaggatc ttctgctgct catacataaa gtaagcatat gcgacacggc tgcttcttcc
    11701 tacccgccct cgcaattggt ataacgtgga taatcccata taatcagcgt tctcaacgaa
    11761 caacgtattt gcgttcggga tatctactcc tgtttcaatg atggttgtag tgacaagaac
    11821 atcatattga ccttcaataa attcaaaaag cgtattttct aattgcgcct ctgtcatttg
    11881 cccatgagca taaccgatcc gtgcttccgg aacgagttct tggatttctt ctactttttg
    11941 ttcgatcgtt tctacccgat tatataaata gaatacttgt ccacctcgtc ccatttctcg
    12001 atggattgct tcgcgaatag ccccaggatt tttttccata acatacgttt ggatcggata
    12061 acgattcgca ggcggtgttt cgattactga aagatcccgc acgcctaaca tcgacatatg
    12121 caaagttctc ggaatcggtg ttgcagtcag agtcaaaaca tccacttgtg cacgtaactg
    12181 tttcaatcgt tccttatgtt ttacaccaaa acgttgttct tcgtcaatga tcagtagacc
    12241 caaatcgcta aattcaatat cttttgacaa aattcggtgg gttcctacaa caatatcaac
    12301 ttgacctgta cgcagttgtt cgatggtttc tttttgttgc tttcttgttc tgaaacgact
    12361 taatagcccg atatttacgg ggaaaccttc aaatctttcc agcatcgttt catagtgctg
    12421 ctgtgccaag atcgttgttg gaactaaaaa ggctacttgt ttgctttcct ttatcgcttt
    12481 aaaggccgct cgaagcgcta cttctgtttt cccataacca acatcaccta cgagtagtcg
    12541 atccattggt ttttcttttt ccatatcccg tttgatctcc gctgcacttc tcaactggtc
    12601 atcagtttca gagtagggga aggcattttc gaattctttt tggtaggcgt catcaggtcc
    12661 aaaagcatat cctttttctg actctcttgc ggcatataat ttgattagat cgtcagcgat
    12721 atcctcgatt tttgaagaga cttttcgctt ggttttcgtc cattcacttc cgcctagctt
    12781 attgatgcga ggcgctttgg cttcagaggc gacatatttt tggatcagat tcagttgagt
    12841 aacaggaata aacagtttgt cgtcgttttg atacaaaata gtcatatagt cttggtgaac
    12901 gccatctact tctagcgttt ccatcccaat gtatttcccg ataccatgat tggcatggac
    12961 aacgtaatct cctgctttta actcattata gcttttcaat cgctctgcgt ttgttactgt
    13021 ttgacgtctc gtttgttttt tcgtcgtttt ttggaaaatt tctttttctg tgatagctac
    13081 tattttttct tgaggaagtt caaaaccagc ctgcaaagct ccttcaacta attgtacctg
    13141 tcctctgatc aatgcatttt tttctgtttc tactactaat atgtcttcat ctcgaagcat
    13201 ttgttctgct ttgcgtattc tgtcctttgt cggaataaag atcacaacag tctgtttttg
    13261 cttgcgccaa cggtccattt ctgttttcag caatggcatt tgtccgaaga actgttgcat
    13321 cgtccgatat tgaaaattat ggattgcttg gaaacgaaga tttcccatcc ctttttggaa
    13381 gagtgagaaa aaggttgtgg tgaacttttc cttctgcacg attttttgta tatctgctga
    13441 aaatgtctgc tcagaaaaca cccgcaattc gctgattttt tgagtctgcc attctgccgc
    13501 ttccctttcg atttcccgat ttgtttccat gattcgctga taatcatcaa cgactagtaa
    13561 actatttgaa gggaaataat ccaagatcgt cacagattct tggtaaagaa gatctgagta
    13621 gaattttgct tcttctgtcg ggacacctgc ttgccagctt gaagtcagct gaccgaagta
    13681 atcttgcaaa aactcgcggt ctgcttcttc tgtggtcgca gcaagccgtt tttctagcat
    13741 tttttgcatt tgctctattc catgttctag atcctctggt ccgtagactt gttcactcgt
    13801 tggggaaacc cagatttctt ccgttttttc gattgagcgt tgtgtttctg cttcaaaata
    13861 ccgcatagaa tctatctcta catcaaatag ttctacacga acaggatagg ttgtcgttaa
    13921 cgggtaaata tcgataatgc ttcctcgaat actgaattct cccggttttg cgaccatctc
    13981 ttctcgtaca tagcccatca aagtcaattg gcgaggaaga ttttccacgt ctatctcatc
    14041 accaatatgc caattcaatt gcgcctgtag ccaagttttc ttattcggca gtcgtttgtg
    14101 caaagatgcg actggcaaca aatagatacc tgcttttttt tcttgaagtg cgttaagcgt
    14161 tgcaactctc tcgcctcgcg cttctggaga agaaaaggcc atttcagcag aaagcacttc
    14221 atccactgga aataaatgga tctgatcttg cggaatcaca tgttgcagat cttctgctaa
    14281 ctgattcgca taatacaaat ttggcatcag aataatcatg tttttatttg ttttcttaaa
    14341 cgctcgagca aatagaagtg ttttcgctga gcccgctaat cctgtgatta gttgtctagg
    14401 cattttttct tctaaattgc tgacccattc ttttacttgc ggatcttttc cgactaattg
    14461 aataatatcc attccttttc ctccttcctc aattgaatcg attcatcgca tccacgaacg
    14521 aatgcccttc tatgagatat tcgactgctt taacagattg acacatgctt tcttctatca
    14581 aaggctgatt ttctttgctg aaaggactaa gcacatgctg gactactgtt tttttccctt
    14641 ctggcctgcc gattcccacc ttgattcgat caaagacatt cgtattcaaa tgggaaataa
    14701 tacttttgat accgttatgc ccgccggcac ttcccttttg acggagccgg atttttccca
    14761 ctgccagatc caaatcatcg tagattacga ctaattcctc tggataaatc ccaaaataag
    14821 tcattagtgg gccgactgca cgaccagatt cattcatgaa tgtttgtggt ttgactaaaa
    14881 ggatcttttc tccattatga aaaaattcgg caacttctgc ttcgaacgga ttttttttga
    14941 aagtagcttg atgctcgcgt gcaattttat ccacgaccat aaagccgata ttgtgttttg
    15001 tatattggta tttggtacct gggtttccta acccgacgat cattttcatt tttgttttcc
    15061 acctaattct aaaaagcagc acaaaaggct ggactgctaa ttagcggtcc agtccatcga
    15121 gcttttttct tttttatact tgtcaatgca tagtataaca caaaacaagg cgtttcggct
    15181 aaaagagaat cgttaataaa tgataaagaa attaaaaatt tcttcaaagt ttaatgaaat
    15241 aattgatata taaaaatagt gaaataacgc acatgtaagc ttttacatat aatacaacct
    15301 tgttatctgt tatattttat agccaaatag cgtgacatgg ggcttgagaa atgttagcat
    15361 aagcatggga aaaaacaaat caatggaagg attgatacta aatgactgca gctgcagaaa
    15421 aaaaagatca tcaaaaagtt attcttgttg gagacggcgc cgtaggttct agctatgcct
    15481 ttgctctagt tactcaaaat atcgctcaag aagtaggtat tgtggatatc aatactgcta
    15541 aaactgaagg agacgcaatt gacttgtctc acgctttggc atttacttca cctaaaaaaa
    15601 tctattctgc tacttacgca gacgcacatg atgctgactt agttgttatt acagctggcg
    15661 caccacaaaa accaggtgaa actcgtttag acttagtaaa caaaaaccta aaaatcaacc
    15721 gcgatgttgt cacacaaatc gttgaatcag gatttaacgg tatcttttta gttgccgcta
    15781 acccagtaga tattttgact tactcaactt ggaaattctc aggtttccct aaagaacgcg
    15841 taatcggttc aggtacctct cttgactcag ctcgtttccg tcaagcactt gcggaattag
    15901 ttgacgttga tgcacgtaac gtccatgctt acatcttagg tgaacacgga gattcagaat
    15961 tcccagtttg gtcacatgca aatgttgccg gcttgcaaat ctatgaatgg gtaaaaaaca
    16021 acccagaaat cgatgaagaa gctatggtta acctattctt tggcgtacgt gacgctgctt
    16081 acacaattat cgagaaaaaa ggcgctactt tctatggtat cgcagtagca ttagcacgta
    16141 tcactcgtgc catcttagat gatgaaaatg ctgttcttcc tttatcagta ttcatgaatg
    16201 gcgaatatgg attgaacgac atctacattg gtgcacctgc tgttatcaac cgtcaaggta
    16261 tccaaaaagt aatcgaaatt cctttaagtg acagcgagca agaccgtatg gctgcttctg
    16321 ctaagcaatt aaaagaaatt ctagatgaag cttttgctaa actagacgct gaataatctt
    16381 tgaacatgac ggaaaacatc tattcggtgt tttccgtttt tttattttat cacccttatg
    16441 gtttctaaat tttttcataa agtagagata accttcgtct tttcctctaa attatgctat
    16501 catgagaccg ttccacccta aacttttact taaggagttg tcgatatgac aagatcttcg
    16561 catcgaaaaa aatcgaaaca tgttgctttg ctttcagttc ttggtgttct cttagtgctg
    16621 atcagctttt atacctatcg cagtacatac tacacaaagc attttttgcc gaatacagaa
    16681 ataaatggaa taaatgtcag caatctaaca gtcgaaaaag caaatgaaaa attaaaagaa
    16741 gcttattctg ataaaaaact ggctattaaa gaagatggaa aagtctggca ggaagtacca
    16801 aaatccgagc tcggctacaa agatgatttc acttcggagc tttctccgat cctaaatgaa
    16861 caaaacggat ggacttgggg aatgacttat gtctcagcgg cagaaaaaca agaaatagat
    16921 cctgtcagtc aaaaccacca aaaactagac actaccgttc agacattgac aactaagctg
    16981 actgatttga acaaagaccg gacacctact actgatgcaa cgatcgaaaa agcaggtgac
    17041 tctttcgtta tcaagcctga agtcaatgga aatacgatcg acgtcgatgc tgcggtcaaa
    17101 caattaaaaa gtgcggtaaa ctctggtaaa gatacaattg aattgactga attcaaagaa
    17161 aaaccaaaag taacatctga agacagctca ctgaaagaac aactcgcatc catgaatgct
    17221 atcgcaaatg taaaagctac ttacagtata aacggtgaga ctttccagat cccatcaagt
    17281 gatattatga gttggctgac ctacaatgat ggaaaagtcg atttagatac agaacaagta
    17341 cgtcaatatg taacagattt aggcacaaag tataacacaa gtacgaatga cacaaaattt
    17401 aaaagtacaa aaagaggaga agttacggtc ccagttggca cttacagttg gacgatccaa
    17461 acagacagtg agacagaagc attgaaaaaa gcgattctgg caggccaaga ttttactcgt
    17521 tcacccattg tgcaaggtgg cacaaccgct gatcatccat tgatcgaaga tacgtatatc
    17581 gaagttgatc tggagaacca gcatatgtgg tattacaaag acggaaaagt ggcccttgaa
    17641 acagatatcg tttccggaaa gccaactaca cctacacctg ctggagtctt ctatgtttgg
    17701 aataaagaag aagatgcaac tttaaaagga acaaatgacg atggaacacc ttacgagagt
    17761 ccggtaaact actggatgcc gattgactgg acaggtgttg gtatccacga ttcagactgg
    17821 caacctgaat acggtggaga cttatggaaa acccgcggtt cacacggctg catcaacacc
    17881 ccaccaagtg taatgaagga attattcggg atggtcgaaa aaggaacgcc tgtattggtc
    17941 ttctaacaaa aataatatat aaaaagaaag cacccgtacg attggtacag gtgctttctt
    18001 tttattatct aacaatgtgc tacttacatt tcagcagcag taaagacttc tgaaacatca
    18061 tcatcgtctt ctagcttatc tactagacgt tccaattgct ctttttgttc ctcatttaaa
    18121 tcaatcgtcg tttgtggaat catcgtcaat tctgcttgcg ccaaagtgaa ctctttttcc
    18181 aactcatctc gtacagcagc aaaatcttct ggtgcagtat aaatctcgaa tacttcagga
    18241 gaagtttgca gatcttctgc ccccgcctct aatacatcct caaacatcgt ctcttcatca
    18301 acagtcaacc catcgcgttc aatagcgata tatcctttgc ggtcaaacaa gtaactgact
    18361 gaacccgttt ctcccagtga tccaccgttt cgagtaaaag ctactcggac atttgtcgct
    18421 gtccgattac ggttatctgt caatgcatgg actaagattc ctactccacc cggaccatat
    18481 ccttcatacg tgatttcatc gtaattcgtt tcatctacgg cactcgtagc ctttttaatc
    18541 gcccgttcca cattgtcgtt aggcatattt gcagcttttg ctttgtccac aacaagccgc
    18601 aaagctggat tcatagatgg atcaggaccg cctgctttag ctgccatata aatttcacga
    18661 gaaagtttct gaaagacttt ccctcgtttt gcatcttggg cattttttct tccttggata
    18721 ttatgccatt tactatgtcc tgacatgatt tttcctccct tgttcttttg agaatacact
    18781 tctattctag tactatttca caaaaaaaca aagccacagc caatctataa acgcttcttg
    18841 aatgccgcaa aaagcacaca taatatcaca gcagtcagag caccgatcga atccaacatg
    18901 acatcttgga acataggtgt tcgtccaccg gtcatcatct gatggaattc gtccaaacct
    18961 gcgtaccctg ttgctgaaag ccaagcaagg atcgctgtca gccaccaaat ttttagcttg
    19021 gggaaaacac ctaaaaacaa gctgcctccc aaaataaaat aggtaccgaa atgtgcgccc
    19081 ttccttaaaa agaactctaa aaatttggcg tagcccagat ggtcgatact caccatactt
    19141 ccaccataat taaaacgtat acccgctaat gtgtctttaa atggctgatt aggcagccag
    19201 ctttctaatc gcgaaacttg tgattgctgt ccgtaagttt gagaagaact gtaaaataag
    19261 attataacga ctatcagtgc gattactaaa taaatatttc cgtttttcat ttgttttttt
    19321 gaagaattca taagtcacct ctgtatttta tcttagactt tttttgaaga aacaacaatc
    19381 attttcatag agacttcttc cataaaaaag tgctatactt aattttgtat tacaatatga
    19441 agggagtttt ttcatgagtt attcattaaa ttggaatcta gattctattt tttccggagg
    19501 cagtcattct gatgctttga accaacggat gaagcaattg gaagaccaaa tgaacgagta
    19561 ttatcaccgc gtaacaaaat ggtcacctag ttctgacaat gcagagcagt taaacgctat
    19621 tcttcaattg caagaaacga ttacgaatgg ttttacccaa tgcagcagct atattactgc
    19681 attgctttct gccaatgtca atgattcaga tgcaaaggtc ttatcaggca agctttacgc
    19741 aatgctgcct cgtctgcaat cagccgaaac tgtattgtca aagaaatttg cagaaatatc
    19801 tgacaatgat tggaatcaga tgctttctca atcttcgttt gaaacaattg cttttcgttt
    19861 aaacgagatt cgtcgtgatg gctcacaatt attatcagaa gctgaagaaa acattataaa
    19921 tacgctttct ttagatggtc taaatgcttg gagcagtcat tatgatacga ttgtagccag
    19981 catttcgatt cccttcgaac aagatggaca agtagtcgaa ttatctgctg gacaagcctt
    20041 caataagatg atgggcgatc cagatccaaa agtcagagaa acacttttcg cagcatggga
    20101 agaagcctgg aaagaaaagg cacccctctt cacggatact ttgaatcatt tagatggttt
    20161 tagactttct gactatgaac ttcatggtgt cacagatttt ctacaaaaac cattagagta
    20221 caatcggttg aagaaagaaa cattgtctgt catgtgggat acaatccaga aaaacaaaca
    20281 accccttgtt aattacttga ctagaaaagc taatcttttc ggtaaagaaa aaatggaatg
    20341 gcaagatcaa gatgcaccta ttattttagg cgatttgaaa gaaaaaacct ttagttttga
    20401 cgaagcagca gcatttatta tcgaaaactt taacaaattc agtccaaaaa tggctaaatt
    20461 tgcccaatct gcttttgaaa agagctggat cgaagcagaa gatcgtcctg ggaaacgtcc
    20521 tggtggttat tgtactgagt taccagaaac aaaagaatca aggatcttta tgacctacag
    20581 taattctgtt aatgaggttg cgacacttgc tcatgaacta ggacatgctt tccatagcag
    20641 cacgatgtgg gatttacctt ctttaaatcg cgaatatgcc atgaatgtcg cagaaacagc
    20701 aagtacattc gcagaactga tcgtagccga tgctacatta aaagtcgcaa aaacaaaaga
    20761 agaaaaaatc aatttgctag atacaaaact gcaaaatgct ttagctatgt tcatgaatat
    20821 ccattcccga ttcatttttg aaaatcgatt ctatgaagca cggcaagaag gattagtctc
    20881 agaagataag atcacagaga tgatggttga ggcgcaaaaa gaaggctatc aaggagcttt
    20941 agctacttac catccatatt tctgggctgc aaaattgcat ttctttattg atgacgtacc
    21001 gttttataac ttcccataca catttggcta cctctttagt ttgggcatct atgcttacgc
    21061 caaccaaaag ggagcaaatt ttgaagaaga atatatccat ttactacgcg atactgcctc
    21121 aatgacgacg gaagatcttg cgaagaaaca tttgaatgtc gatcttaccc aaccagattt
    21181 ttggcaagca ggtatcgaca tggtgactga agatatccaa acgttcatgg aattgacaga
    21241 agaatttatc tgatttctat tttatcacaa taaaaaaaga gttagtccag aatgggctaa
    21301 ctctttttga ttaatcattc ttacatgctg acagcaaagt caggggcaaa ccattgaact
    21361 gaaccaactt ttacgctttc gcctggttga ggagcatgga tatattgtcc tccgcctaaa
    21421 gcaatcgcta cgtggtaagt tccgccttgt gacccccaga ataacaagtc tccagctttt
    21481 gcttgagaaa ctgaaatttt tgttccagct gattcttgag gaactgtcca accaccgatg
    21541 tcacgaccag ttacttgcat gtaaacatag cgtgtgaacc ctgagcagtc aaagccactt
    21601 ggatctttac cgccccaaac atatggagta ccaatatatt tgtaagcttc tgctacgatt
    21661 gctgcaccat tcacacttcc agaaggagct ggagcaggtg ttacaggttt tggttgttca
    21721 ggtgttggtg ttggcgttgg agccggagta ctacttcctg tgccgtttcc tgtatcaaca
    21781 ctttgatctg ttgatggtgt tgtaggcgca ggtgttgttg attcttctgt tg
//
LOCUS       DAFBSV010000048        21595 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.049, whole genome shotgun sequence.
ACCESSION   DAFBSV010000048 DAFBSV010000000
VERSION     DAFBSV010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21595
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.049"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            178..405
                     /locus_tag="LLB18_001659"
     CDS             178..405
                     /locus_tag="LLB18_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBK5244661.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            421..1587
                     /locus_tag="LLB18_001660"
     CDS             421..1587
                     /locus_tag="LLB18_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBK5244662.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            1822..2865
                     /gene="hrcA"
                     /locus_tag="LLB18_001661"
     CDS             1822..2865
                     /gene="hrcA"
                     /locus_tag="LLB18_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HBK5244663.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            2959..3522
                     /gene="grpE"
                     /locus_tag="LLB18_001662"
     CDS             2959..3522
                     /gene="grpE"
                     /locus_tag="LLB18_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBK5244664.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDRYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            3573..5402
                     /gene="dnaK"
                     /locus_tag="LLB18_001663"
     CDS             3573..5402
                     /gene="dnaK"
                     /locus_tag="LLB18_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBK5244665.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            5553..6719
                     /gene="dnaJ"
                     /locus_tag="LLB18_001664"
     CDS             5553..6719
                     /gene="dnaJ"
                     /locus_tag="LLB18_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBK5244666.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(7087..7824)
                     /locus_tag="LLB18_001665"
     CDS             complement(7087..7824)
                     /locus_tag="LLB18_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBK5244667.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(7826..9328)
                     /locus_tag="LLB18_001666"
     CDS             complement(7826..9328)
                     /locus_tag="LLB18_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HBK5244668.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIEKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            9587..11581
                     /gene="uvrB"
                     /locus_tag="LLB18_001667"
     CDS             9587..11581
                     /gene="uvrB"
                     /locus_tag="LLB18_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBK5244669.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            11591..14407
                     /gene="uvrA"
                     /locus_tag="LLB18_001668"
     CDS             11591..14407
                     /gene="uvrA"
                     /locus_tag="LLB18_001668"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBK5244670.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            14670..15935
                     /locus_tag="LLB18_001669"
     CDS             14670..15935
                     /locus_tag="LLB18_001669"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HBK5244671.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            15939..16670
                     /locus_tag="LLB18_001670"
     CDS             15939..16670
                     /locus_tag="LLB18_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HBK5244672.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            16805..17689
                     /gene="rapZ"
                     /locus_tag="LLB18_001671"
     CDS             16805..17689
                     /gene="rapZ"
                     /locus_tag="LLB18_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBK5244673.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            17686..18684
                     /locus_tag="LLB18_001672"
     CDS             17686..18684
                     /locus_tag="LLB18_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBK5244674.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            18718..19653
                     /gene="whiA"
                     /locus_tag="LLB18_001673"
     CDS             18718..19653
                     /gene="whiA"
                     /locus_tag="LLB18_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBK5244675.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            20196..20846
                     /locus_tag="LLB18_001674"
     CDS             20196..20846
                     /locus_tag="LLB18_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244676.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            21033..>21595
                     /locus_tag="LLB18_001675"
     CDS             21033..>21595
                     /locus_tag="LLB18_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HBK5244677.1"
                     /translation="METVRLWIFMKNFRSALRNVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
BASE COUNT         7104 a         3658 c         4712 g         6121 t
ORIGIN      
        1 tttttttatg aataaaataa ggacaaaatt gtttaggaag aatcatgagt gtaaaaaaat
       61 catccaagaa gtcgattctt ggatttttta gtggatttgt tcgccaaata cgtttagtat
      121 gcgtatatga gaggttgtaa gcaaagcgtt gtggtctgag cacttaagga ggaatctgtg
      181 aaaatagctt ttcatatttt tgcagatttt gacttaatgc cgaaggtcag ctttgcgatt
      241 accgtttatc gagaggctgt aaaagcaccg tgtagctccg atgacaataa gcaagcattt
      301 ttagagctag gtttccttga ttctaaatat gcggcttatt tcaatgagtt ggtgcttgaa
      361 cgcgatttta agaaggtcga aaacaggcac gacttttcga cgtaaggaga aagaatttca
      421 atgatagaaa caataaatcc cgcagaaaac aaggtttctg cgtacattca tatcccattt
      481 tgcgagcata tctgctatta ctgtgacttt aataaagttt ttttagaagg gcagccagta
      541 gatgagtatg tggaaatgct gctgaatgaa atgagattaa tgctggaaag tcatcctaca
      601 gcgaatttgg aaacacttta tgtaggaggc ggaacaccaa cttctttatc tgctaaacaa
      661 cttgatcgac tattatcagg tgctagagag atcctgcctt ttcaaaatgg taatgagttt
      721 actgtagaag cgaatcctgg tgatttgacc cgtgaaaaac ttcaagtgat gaaaaactat
      781 ggcgtcaatc gtttatccat gggagtgcag acatttgaca atcgcttatt gaaaaaaatt
      841 ggacgtaaac atactgcaga agatgtgtat caaacaatgc aatttttaga agcagaaaat
      901 tttaccaatg taagcatcga tttgatttat gcattaccgg gacaaacact agaaggatat
      961 cgggatactt tggaaaaagc tttggctttg gatctgcctc actattcttt gtactcattg
     1021 atcctcgaaa acaaaacaat gttcatgaac tgggtacgac aaggaagact cgaactgcct
     1081 gatcaggaaa cggaaaccag aatgtttgaa gagacgattg aagcaatgga aaagcatgga
     1141 cgtcaccaat atgaaataag taactttggg ctctccggac atgaatctca acataacctc
     1201 atgtactgga acaatgacca ctattttggg tttggagctg gtgctagcgg ttatcttgga
     1261 gatattcgtt accgcaacaa aggaccgatc caacactatt tacgcccatt acgagcaaat
     1321 gaacgcccgg tattggaaga agaaaaattg acacgaaaaa atcaaataga agaagaaatg
     1381 ttcttaggac taagaaaaaa aacagggatt actaaaaaac atttctatga tcgctatcaa
     1441 aaaacaattg aatcggtgta cggtgatgtg ctaagggaat tagagcaaga agggttactt
     1501 gttaatgaag aagaccgtgt ttatttgaca ccaagaggga cttttttggg gaacaatgtg
     1561 tttgagcgct ttttatttga aaaatagttt gaagaatatt tgttttttat cgaaacttga
     1621 aaagaaaaag tttagaaagt ttgacaatga ggtattgaag tattgatata actggattta
     1681 catcaattat ttagaattag cactcttgtg tttagagtgc taaaaaatgg agtctttctc
     1741 ttgacaggag aagggcttct tgctatattt ataagtgaat tagcacttag aatatatgag
     1801 tgctaatgag aggtgaggaa gatgttaaca aagcgacaaa acgacatttt acgtctgatc
     1861 atccaacact atacgagtag tggcgtgccc gttggttcca aaacattaat gtctgaggga
     1921 gtcaaggcca gctcagcaac gattcgcaat gatatgaaag cattagaaga tgaaggattg
     1981 ctgttgaaga ctcactcttc ttctgggcgg attccatctg ctttaggcta tcgttattac
     2041 gtggatcatt tgttaaaacc tgctcgcgta gcagaagatg atttgctgct gattcgtcag
     2101 tctctaggca gagaatttca tgaaatcaat gagattatta agcaatctgc tgagatatta
     2161 tctgagctga caagctatac gactttttca ttgggacctg aaataaaaga ccgccgactg
     2221 actggctttc gtatcgtacc cttgaataat cgacagatta ttgctatcgt cgtaacagat
     2281 atggggaatg tagaaagcca agtgttcact cttcccgaat atatgggaag tcaggaacta
     2341 gaaaaaatgg tacagattgt aaacgaccgt ctagtcggag atcctctgat gacggtgtac
     2401 cataaacttc gtacggagat tccgatgatt cttcataaat atttccagac gacagaaggg
     2461 atgtctcagt tatttgacac cgttcttggt catgtttttg aagaaaaggt ttatgtcagt
     2521 ggacaaatga atctcttgga ttatgagccc cgtcaagatc ttgatcagtt caaatcgatg
     2581 ttttctttta tgaaagactc agacggactt acacaaatga tcactccgat ggatagcaat
     2641 attcatatca agattggtgc tgaattaggc aatgatttat tgcagaatat gagtatgatt
     2701 caagcaagtt acgagataga tggtcatgga agaggtacaa tagccttgtt agggcctact
     2761 agtatgcctt attctcggat gttcggtcta gtcgatgttt atcgaagaga actagcagct
     2821 aaacttgctg attattaccg ctcgcttgac ttgtcaaact cgtaatgtga ataacgaagc
     2881 tatttgcagc tgatcgttct ctctttctta gtaagagcaa tcaaacagct gactgaataa
     2941 tgaaaggaag actgtatcgt gaaagaaaat caagaagaac tagataaaga aatgacagat
     3001 gctcagccag aaccggaaat cgatgtcgaa gctgcagaag attcgggtat ttcagaagct
     3061 gaagcggaag aattcgaaac agcgaaatta aaagctgagt tagaagaaat ggaagataga
     3121 tacttgcggg ctcgtgctga aatcgcaaat atggcaaatc gaggaaaaaa tgagcgtgag
     3181 caattacaaa aataccgttc acaagattta gccaaaaaat tacttccatc aattgacaac
     3241 ctggaacgtg cattagccac agaagtgtca gatgatcaag gggcaggttt gaaaaaaggc
     3301 gtggaaatgg tcttggaaag tttgcgtaac gcactggaag aagaaggaat tgaaaaaatc
     3361 cctgctaaag gagaagcctt tgatcctaat cttcatcaag cagtacaaac tgttccagcg
     3421 actgaagata caccagccga tacgattgta gaagtactac aagaaggcta caaattacat
     3481 gatcgcgtgt taagaccaac tatggtcatt gttgcacaat aattgtgcgg atataaaact
     3541 tacactttca attaaagaag gagacgttaa ttatgagtaa aattatcggt attgacttag
     3601 gtacgactaa ctctgcagta gcagtattgg aaggaaacga agcaaaaatc atcgctaacc
     3661 cagaaggaaa ccgtacaaca ccttctgttg tatcattcaa aaatggagaa atccaagtag
     3721 gggaagttgc aaaacgtcaa gctgtgacaa acccaaatac gatttcatca atcaaacgcc
     3781 atatcggtga agcaggttac aaagtagatg tagaaggtaa atcatataca ccacaagaaa
     3841 tctcagcaat gatccttcaa tatatcaaag gattcgcaga agactattta ggtgaaaaag
     3901 tcgaaaaagc agttatcact gtgccagctt actttaatga tgcacaacgt caagcaacaa
     3961 aagatgctgg taagatcgct ggtctagaag tagaacgtat cgtcaatgaa ccaactgcag
     4021 ctgctcttgc ctatggttta gataaaacag atcgcgacga aaaaatctta gtattcgacc
     4081 ttggtggcgg tacttttgac gtatctatcc ttgaactagg agacggtgtc tttgatgtat
     4141 tgtcaacagc tggcgacaac catctaggtg gggacgactt tgataacaaa atcatcgact
     4201 acatggtagc agaattcaaa aaagaaaaca gcattgactt gtctcaagac aaaatggctt
     4261 tacaacgctt gaaagacgct gctgaaaaag cgaaaaaaga tttatctggc gtatcaagca
     4321 cacaaatcag cttgccattt atcacagcag gagaatctgg accattgcat ttggaaatga
     4381 cattgacacg tgcaaaattt gatgaattaa cagctgactt agtagaacgt acaaaagtac
     4441 cagtacgtca agcgttaaaa gatgcaggtc tgtcacaatc agaaatcgac gaagttattt
     4501 tagtcggtgg atctactcgt atccctgcag ttgtagaagc agtacgtaaa gaaacaggaa
     4561 aagaaccaaa caaatcagtt aaccctgatg aagtagttgc tatgggtgct gctatccaag
     4621 gtggcgtgat cactggtgat gtgaaagatg ttgttttact tgacgttaca ccattgtcat
     4681 taggtatcga aacaatgggt ggagtgttca ctaaattgat tgaccgcaat acaacgattc
     4741 caacaagtaa atcacaagta ttctcaactg cggcagataa tcaaccagca gtagacatcc
     4801 atgtattaca aggtgaacgc ccaatggctg ctgacaacaa aactctagga agattccaat
     4861 tgacagatat tccagcagct cctcgtggta ttccacaaat cgaagtaaca ttcgatattg
     4921 ataaaaacgg gattgtaaat gtatctgcga aagatctagg tacacaaaaa gaacaaaaaa
     4981 tcacgatcaa atcttcttca ggtctaacag atgaagaaat cgaacgtatg gtgaaagatg
     5041 cagaagcaaa cgctgaagca gataaagctc gtaaagagga agttgaccta cgtaatgatg
     5101 tagacgcatt gctattctct gtggacaaaa cattgaaaga attagaaggc aaagtggacg
     5161 aagaagaagt gaaaaaagca gaaacagctc gtgacgaatt aaaagccgct gttgaagcaa
     5221 acaacatcga ggaaatgaaa actaaacgcg atgcattgaa cgaaatcgtt caaaacttga
     5281 ctgttaaact atacgaacaa gctgcacaac aacaagctca agaaaatcca gaagcagctc
     5341 aaggcggagc agatgatgtc gttgatgctg attttgaaga agtcgatggc gacgataaat
     5401 aatcagttca ctgaatttcg agagaaggcc aaagttgcta ctttggcttt ttcttttgaa
     5461 aaatagtttg aagtatcggt ttttgtttca aacaaaatat gatatgataa caagcgacgt
     5521 gaaaatgatg agaaccaata ggaggaaagc ctatggcaac aaaacgtgat tattatgaag
     5581 tcttagggct ctcaaaagga gcatcagaag atgaaataaa gaaagcttat cgtaagcttt
     5641 cgaaaaaata ccatcctgac atcaataaag aacctgatgc ggaagaaaaa ttcaaagaag
     5701 tatcagaagc atatgagatt ttaagtgacc cgcaaaaacg cgctgcatac gaccaatacg
     5761 ggcatgcagg cacagatcca aattacggtg ctggtggagc tggtggcgga tttggtggat
     5821 tcggcggctt ctctggtggc ggcttcggtg gttttgaaga tatcttcgac tctttctttg
     5881 gaggaggcgg tcgatcagtc gatccaaatg cgcctcgtca aggtgctgat ttgcaatata
     5941 cggtcgactt gtcttttgaa gaagcgattt ttggtgtaga aaaagaaatc aagtataatc
     6001 gggaagaaat ctgtcatact tgtggtggaa acggtgcaaa accaggcaca caaccaacta
     6061 cttgtcataa atgtcatggt gcaggtacga tcaatgtaga acgccaaacg ccacttggac
     6121 gagtgatgag ccgtcaaact tgtgatgttt gtcatggcac agggaaagaa atcaaagaac
     6181 cttgtccaac ctgtcatggc tcaggacatg agaagaaagc acattcagtt aaagtgaatg
     6241 taccagctgg tgtagaagaa ggacaacaaa tgcgtttagc tggtcaagga gaagctggag
     6301 aaaacggcgg accatttggt gatttgtatg tggtctttcg tgtagaagaa agtgatatct
     6361 ttgatcgtga aggttctgaa atttactatg aattgccttt aagttttgta caagcagctt
     6421 tgggggatga agtccaagta ccaactgtcc atggagatgt gaaattgaag atccctgctg
     6481 gaacacagac aggtacgaac ttccgtttac gtggaaaagg cgctccgaag ttacgtggtg
     6541 gtgcaacagg cgaccaacat gtcaaagtaa aactgatcac accgaaaaat ctaaatgaac
     6601 aacaaagaga agcattacgt gcattcgctg aagctggcgg catcaaagtt gaagaacagc
     6661 aagaagacgg tttcttcgat aagtttaaag atgcttttgg cgggaaaaag cggaagtagt
     6721 ttttctagta aaaatataaa gtagacttgc ccaaattttc tatttctagt aaaaacgcta
     6781 agtcattaat aattaaaaac cagacgaaca atcatacgtt cgcctggttt ttttgtagtt
     6841 gtcatgtttg taccaacaaa aaagccagct ttagaataag ataatcatca tagtttctga
     6901 aggtggtatc gactatgtac ttgatatcgt caatgaaccg atggtacttt cttatgcgat
     6961 ggaacaggta gagcgattgc ttgtttgtgc aggagaacaa gcgatgcggc tggtacagtt
     7021 aagtgaaaaa acaagaaact aaaaatgccc ggtcgtcatg aagcaaccgg gcatttttgg
     7081 tttttattaa atattcaata ctttattcaa gaaatctttt gtccgttcat tttgcggatt
     7141 ttcaaagatt tgttgaggcg ttccgtcttc taaaaagttt ccgtcgtcaa tgaacatgac
     7201 acgattggcc acttctttag cgaagcccat ttcgtgcgta acgataacca tcgtcatacc
     7261 ttgttctgct aactttttca tgacgttcaa gacatcaccg accatttcgg ggtcgagtgc
     7321 agatgtaggc tcatcaaaaa gcatgatgtc agggttcatc gctagagcac gagcaatagc
     7381 cacacgctgt ttttgtccac cagaaagcat ttcaggatac atatcttttt tatcttctag
     7441 accaactgtc tgcagtaatt tgattgcttt tttctctgct tcttctctag attctttctt
     7501 caggtccatc ggtgctaaaa tgatgttttc caaaatagaa agatgaggga ataggttaaa
     7561 gtgctggaat accattccga tatgttgtct caccaagttg atatctgtgc ttttatccat
     7621 caagtgggcg ccgtcaataa taatttcacc gtcagaaggt tcttctaaac gattcaagca
     7681 acgcaaaaat gtactttttc ctgaacctga agggccaatg atacagacga catctccttc
     7741 gttgatggat acattgatgt cgtttaatac tgtgttatcg ccgtattttt tgactaaatg
     7801 ctcaactaag attttttctg ccatcttact tcaccttctt ttctaaaact tttgctaatt
     7861 ttgtcaatgc tgtgatcaaa atcaagtaca tgatcgcaat gatcaagtaa acatacgtac
     7921 tttgtgttgt acgtgcaaca atgatcttac cagtttgcag caattcgact acaccgattg
     7981 cggaaatgat cgttgtgtct tttaatgaga taacgaactg attgacgaat gatgggatca
     8041 tgatgcgtat tgcttgtggc aaaatgattt tttgcattgt ccgattataa gaaagaccta
     8101 aacttctgga agcttccatt tgtccgacag gaacggcgtt gatcccgcct cgaacaatct
     8161 ctgcgatata agcacttgcg ttaagagtca aggtgataac accagcaagg aagtcaggaa
     8221 tcgtaaatcc aacgatacca ggcaacccaa agaaaataaa gaacgcaaga accatcattg
     8281 gaattcctcg gatgatatcg acataaatac tagcaattgt gcgaagagcg cgtattggtg
     8341 ctacactgaa taatccaaaa atcacaccga ttactatagc caaagcaaag gagatcaaag
     8401 ttaggagaat tgttctccaa agtcctttca acaatgcttg atagttgttt tggataagtc
     8461 caagaaatgt tgattcatca gcagtggaag actcactaga agtttctgaa ccatccgcta
     8521 catattcttt gataatctta tcgtattcgc ctgttctttt taattctttc aatccttcat
     8581 tgaacatatt aagaagctca ggattttgtc cttttttaac ggcaaatgca tattttccgc
     8641 cagattcttt ttcgatcggt gtttccaatt cttgtccttg tttgatcgca taaccgatta
     8701 ccggataatc atccatcatt gcatcgattg cgccaacttt taacccgtcg tacaattgat
     8761 cagcagcatc aaaatatttg atagaatagc catattcaga ttcatggtcg cttaaaaatt
     8821 cagcactttc ggtaccaact tttgctccga ctgtttttcc tttcaaatct tcataagact
     8881 tgatcgaagt atctcctttt ttgacagcta attggatccc gctatcaaag taagaatcag
     8941 aaaaatcata gcttttcttt cgttcatctg ttacagtcat tccggcaatc attccgtctg
     9001 cttgtcctga ttccaaagct tgcaaagcag cagagaaacc acggtagtcc attcggatgt
     9061 taaatccttg cagtttggcg atgttttcca tcaattttac atcgatgcct tcgtactcgc
     9121 cctttgcgtt ttgaaattca aatggagcaa aagcagagtc actggcaatt acgtatacgt
     9181 cttttttggg ctctattttt tgcattgtct cgcttgtgct tgactctgcc gttgtagtgt
     9241 tgtcagcttg tgcaacatga ccaaacgcaa gtgtcacaag tcctgtcatt aagaaaacaa
     9301 atgagtgaaa taaatgcttt cttttcataa tcaacctcct aaatttccaa tattttatta
     9361 ttataggcga aaagtgctga atcagacaag actgtaagct cgaaaaaatg aaaaaaatgc
     9421 gagtttctaa cattttatgt tataaaacgt aacatgtata ataagataaa aaagtggcga
     9481 aagtatgttc ggtgtggtat aattttttag taaggaatgc ctttgctttc cttttctttt
     9541 tattggtcgt aaaatgaaaa ggaatgaatg aaaaggagga cgaagaatga ttgagagaga
     9601 tacctcccga cactttgagc ttgtctcgaa ataccaaccg gctggtgatc agcctgaagc
     9661 gattaaccaa ttagtggatg gcgtagtcgg cgggaaaaaa gcacaaatct tattaggtgc
     9721 gactggaaca gggaaaacat atacgatttc caatcttatt gagaaagtga ataaaccaac
     9781 actgattatt gctcataata aaacattggc tggtcagctg tacggggaat tcaaggaatt
     9841 tttccctaac aatgctgttg aatattttgt ttcttattat gattattatc agcctgaagc
     9901 ttatgtgcct tcaagcgata cgtatatcga aaaagattca agtgtaaatg atgagatcga
     9961 caaattacga cattcggcta ctagttcatt attagaaaga aatgatgtga tcgtcattgc
    10021 atccgtttca tgtatttttg gattaggttc gccttttgag taccaaaaac aagtagtttc
    10081 gattcgacag ggagcagaac tagatcgcaa tcagttgatt cgtgacttag tcagtatcca
    10141 attcgaaaga aatgatatag attttcagcg cggtcgtttt cgagtgcgcg gtgatgtcgt
    10201 ggagattttt ccggcttcaa gagatgaacg tgccttacgt gtggagtttt ttggagatga
    10261 ggtcgaacgt atccgagaag tcaatgcact gacaggtgaa gttttaggag aaacggaaca
    10321 cgtggcaatc ttcccggcga ctcactttgt gacgaatgat gaacatatgg agcatgccgt
    10381 agcgaatatc aaagcggaat tagaacagcg tttaactgtc ttgcgaaatg aaaacaaact
    10441 tctggaagct caacgtttag aacagcgaac caattacgat attgaaatga tgttagaaat
    10501 gggctacacg tcgggaattg aaaattattc tcggcatatg gacggacgta aagaaggtga
    10561 accgccttat acgctattgg atttctttcc tgaagatttt ttgatcgtgg cggacgaatc
    10621 gcacgtaacc atgcctcaaa tcagaggaat gtataatggt gaccgagcga gaaaacagat
    10681 gctagtagat tacggtttcc gtttgccatc tgctttagac aatcggccac ttcggttaga
    10741 agagtttgaa aaacatgtca atcagatcat ttatgtctct gcgacgccag gaccatatga
    10801 acatgaacaa acagataccg ttatccaaca aatcatccgt ccgacagggc tgcttgaccc
    10861 agtgatcgaa gttcgtccaa tcatgggaca aatcgatgat ctagtaggcg aaataaatga
    10921 acgagtcgaa aaagaccagc gggtgtttgt aacgacattg acgaaaaaaa tggcagaaga
    10981 cctcacagat tatttcaaag aattagggat caaagtcaaa tatttgcata gtgatatcaa
    11041 aacgctggaa cgaacagaaa tcattcgaga tcttcgatta ggtgaatttg atgtgttagt
    11101 tggaatcaat ttgcttcgtg aaggattaga cgtacctgaa gtttcccttg ttgctatctt
    11161 ggatgcggat aaagaaggct ttttacgtag tgaacgttcc ttagtccaaa cgattggacg
    11221 agctgctcgg aatgaagaag gtaaagtaat catgtacgca gacaaagtaa cagattctat
    11281 gcgtctagcg atggatgaaa cgtcaagacg tcgtacgatt cagcagaagt acaatgaaga
    11341 acatgggatc gttccaaaaa cgatcattaa agaaatccga gatttgattt ctattacgaa
    11401 agaatcggaa gatgatacaa aagaagcggt acaagtctcg tacgaagaaa tgacgaagga
    11461 agaaaaagac acgttattga tgaaattaga aaaagaaatg aaagatgcgg caaaagcttt
    11521 ggattttgaa acagccgcga atgtgcgaga tatgatttta gaattaaaag cttcaaagta
    11581 ggaggacaac atggctaacg ataaaattac gattcatggt gcacgtgccc ataacttgaa
    11641 aaatatagat gtaacgattc cacgagataa attcgtggtc gttacaggtt tgtccggttc
    11701 tggaaaaagt tccctagcat ttgatacgct gtacgctgaa gggcagcgga gatacgtaga
    11761 gagcctttct gcttatgctc gtcagttttt aggacaaatg gataagccgg acgtagatag
    11821 catcgacgga ttgagtccgg cgatttctat tgatcagaaa acaacaagta aaaatcctcg
    11881 gtcgacagta ggtactgtga cggaaatcaa tgactattta cgcttgttgt ttgcacgtgt
    11941 aggacatccg atttgtccca acgatcatat cgagattacc agtcaatcag tagatcaaat
    12001 ggcagatcaa gtaatggctt tgcctgagcg cacaaagatc caagtgttgg caccgatcgt
    12061 ggtaaagaaa aaaggacaac ataaaaaaat attcgaacga atccaaaaag agggatacgt
    12121 ccgcgttcga gtcgatggtg agatctatga tttaagtgaa gtgcctgagc tggagaaaaa
    12181 caaaaaacat gatatcgcga tcgtcatcga ccggatcatt gtgaaagaag ggattcgttc
    12241 tcgcctattt gattctttag aggcggccct gcgattagca gacggctatg ctctggttga
    12301 cgtgatcggt gaagaagaaa tgttgtttag cgaacactat gcctgtcctt attgcggatt
    12361 tactgttggc gaactagaac caagactgtt ctcattcaat gcgccttttg gagcttgtcc
    12421 agactgtgat ggtttaggtg tcaaattaga agtcgatcaa gatttagtga ttccagatag
    12481 aacgaagaca cttagtcaag gtgctatcgt tccatggaat ccaatcagct ctcagtatta
    12541 tcctcaaatg ttagcgcagg cttgtgaaag tttcggtatc gatttagata caccattcga
    12601 agaattaccg gaagagcatc aggagatcat cttgaatggg acagatgatc ttttccattt
    12661 ccattatgaa aatgattttg gtggcgttcg cgatgtagaa acgactttcg aaggggtatt
    12721 gaagaatatc gagcgtcgtt atcatgatac gaacagtgat ttcacgcgtg agcaaatgcg
    12781 tctttatatg acagaattaa cttgtcagac atgtaaaggt tatcgattga atccccaagc
    12841 tctatctgtt caaatcaatg gaacgaatat cgggcaaaca aatgagttgt ctattcaaaa
    12901 agcagtagat ttcttctcaa acttaacgtt atctgaacaa gagaaagtaa ttgccaaacc
    12961 gattttaaaa gaagtaaatg acagactttc attcttggaa aatgtgggac tagactatct
    13021 aactttgagt cgcgcttccg gaacattatc tgggggagaa gcgcagcgaa tcagattggc
    13081 tacacaaatt ggatcgaatc tttctggagt tttgtatatt ttagatgaac catcgatcgg
    13141 attgcatcaa cgcgacaacg atcgactgat tggctcatta aagaaaatgc gtgatcttgg
    13201 caacaccctc gttgtagtcg aacatgatga agatacgatg tgggcagcag attatttgat
    13261 tgacgtcgga cctggggccg gagaacaagg cggacaaatc gtggctgcag gcactcctga
    13321 agaagtagct aatgatgaaa attctttgac agggaaatat ctttcaggga aaaaatcaat
    13381 ccctgtacca aaagaacgcc gtaaaggtaa tgggaaagca atcaagatca ctggtgcttc
    13441 agaaaacaat ctgaaaaata ttagtgttga atttccatta ggagaatttg tagcagtcac
    13501 aggtgtgtct ggttctggaa agagtacatt ggtcaatagt atcttaaaga aatcgttagc
    13561 gcaaaaatta aataagaatt ctgctaagcc aggtaaattc aagacaattt ccggctacga
    13621 aagtatcgaa aagatcatcg atatcgatca aagcccaatc ggccggacgc cgagaagtaa
    13681 tccagcgact tatacaagtg tatttgatga tatccgtggg ttatttgctc aaacgaacga
    13741 ggcaaaaatg cggggttata agaaagggcg ttttagtttc aacgtaaaag gcggtcgttg
    13801 tgaagcttgt cgcggggatg gaattattaa gatcgaaatg cactttttgc ctgatgtcta
    13861 tgttccttgt gaagtatgtc atggtaaacg atataattct gaaacattag aagtgcatta
    13921 caaaggaaaa agcattgctg atattttgga aatgacagta gaggatgctg tagaattctt
    13981 caagcacatt ccaaagattc atcgcaaact gcaaacgatt gttgatgttg gcttaggtta
    14041 tgtgacgatg gggcaaccag caacgacatt gtccggtggt gaggcacaac ggatgaaact
    14101 tgccagtgaa ttgcacaaaa tctctaatgg aaagaatttc tatatactag atgaaccaac
    14161 gacaggactt catagcgatg acatcgcccg cttgttgcat gtattacaaa gattagtaga
    14221 tgctggtaac acagttttag tgattgaaca caatctagat gtaatcaaaa cagcagatta
    14281 tatcattgat ttaggaccag aaggtggaga aggtggagga acgatccttg cgactggaac
    14341 accagaagaa atcattaacg taaaagaaag ttatacaggt cactatttga aaaaaataat
    14401 ggtataaaga ggatagatag ctgagatagt taaaaaaaca taaaaaaatg aatttttgct
    14461 tgttttatta atatcagtgt tctagaatca ttacatggta gttctttcta cactgattgg
    14521 tatagataaa aacttcctat aagttcaatc cgttcaaaaa agaattgagc aatcggagga
    14581 gtttcctttg attgcttttt tctttatggt atgatattcc ttgtgtagtt ggaaaagaaa
    14641 aacaagagat tatgagtaag tgagagataa tgatgaacag tattgaaaat gaagaattta
    14701 tccctatatt attaggaagc gacatgaacg tttatggtat ggcacgttct tttaatgaag
    14761 catacggcaa aatctgccaa gcatatgctt cggatcagtt agcccctacc cgctacagta
    14821 aaattgtcaa tgtagaagtt attccaggat ttgataaaga ccctgtattt atcgagacga
    14881 tgcttcgttt ggcaaaagaa agatattctg ataagagtaa aaaatatctt ttgattgctt
    14941 gtggtgatgg atatgcagaa ttgatctccc aacataaaca agagctgtca gaatatttta
    15001 tctgtccata tattgattat tctttatttg aaaggctgat caataaagta agcttttatg
    15061 aagtttgtga agaatatgat cttccgtatc ctaaaacatt gatcgtcaga gaagaaatgt
    15121 tagtaaatgg acatttggaa caggaattgc cttttgaatt cccagttgct ttgaaacctg
    15181 caaacagtgt ggagtatctt tctgtccaat ttgaaggaag aaaaaaagct tttattttag
    15241 agactagaga agagttcgat ttaattttag gccggatata cgaagccggt tataaaagtg
    15301 aaatgattgt acaagatttt atcccgggtg atgatagtaa tatgcgtgtg ctaaatgcgt
    15361 atgtagatga agatcatcaa gttcggatga tgtgccttgg tcatccacta ttagaagatc
    15421 ctacaccagc atcgattggt aattacgttg tgatcatgcc agattataac gaaaaaatct
    15481 atcaaaccat taaggcattt ttggaaaaaa tcgaatatac aggctttgcc aatttcgata
    15541 tgaagtatga tcctagagat ggagaatata aattatttga aatcaatttg agacaaggtc
    15601 gtagcagttt ctttgtgaca ttgaacggct tgaatctggc tcgttttgtc acagaagatc
    15661 gagtgttcaa caaacccttt gttgaaacga cctatggaac gaatcaatca gataaagcaa
    15721 gattatggat gggtgtgccc aaaaaaatct ttttagaata tgctcgggaa aatgaagaca
    15781 aaaaactagc tgagcaaatg atcaaagaaa atcgttacgg tactactgta ttttatgaaa
    15841 aagaccgatc aatcaagcgc tggttgttga tgaaatatat gttccataac tatattccaa
    15901 gattcaaaaa gtattttcat gtgaaagaag gctagttcat ggagaatttt ttcagtattt
    15961 taggcggaat gggcacgatg gcgacagaaa gttttgttcg cttgatcaac caccgaacga
    16021 aagctacaaa agatcaagaa tatttgaatt atgtcttatt caatcatgca acagttcctg
    16081 atcgtacagc ttatatttta gatcgatcag aagaaaatcc aatgccgttt ctgctggatg
    16141 atattgagaa acaaaattta ttgcgaccaa acttcattgt gttgacttgt aacaccgcac
    16201 actacttttt tgaagagtta caagcggcaa cggatattcc tatcttgcat atgccaagag
    16261 aagcagcaaa tgaacttgtc cgtcagcata cgacagggag agtagcgatt ctaggaacag
    16321 aaggaagtat gaaagctgga atctatgaac gcgaagtcaa aaatcttggt ttcgaaacag
    16381 tgattcctga tactgcgctt caagaaaaaa tcaattacct gatctatcat gagatcaagg
    16441 aatcggatta tttgaatcaa gagctctatt acgaaatctt agaggaagcg gtagagcgcc
    16501 taaactgtga aaaagtcatc ctaggttgca cagaattatc tttgatgcat gaatttgctg
    16561 aagataatca ttacccagtg atcgatgctc aatctatttt agcggatcga acgatcgaac
    16621 gtgcattagc tgaaagaagc gaggcattgg atacagcatc ggaaaagtaa aaaaattgga
    16681 tttggggcaa atatcctaaa agatatttgg tccaaatctt tttgtaaaag aaaaagaaaa
    16741 ctggtaatga tacgcccggg atgatataat tttattatgc acaatgtgag aggggttcgt
    16801 aaatatgaca gataatttgc aattagtcat cataacaggt atgagtggtg cagggaaaac
    16861 agtagctatc caaagttttg aagatatggg ctatttttgt atcgataata tgccgcctcg
    16921 attgattcca aaattctggg aattgatcaa agaatcaggt aaagtcacaa aaatggcttt
    16981 aggagtggat ttgcgttctc gttccttctt tgaagaaatc caaaacatgc tgatcgaaat
    17041 cgaaaatacg aacttcatcg acacttctat cttattttta gatgcttcag acgaagaact
    17101 agtggctcgc tacaaagaaa caagacgagc acatccaatg gcgatggacg gtttgatcac
    17161 tgaagggata cgtaaagaac gggcgatact agacgacttg aaagcccaag cttccgtgat
    17221 cattgatacg acaacattga caccacgaca attacgtgaa aaaatcaatg agtcattcaa
    17281 atcaaaggga gaccaaggat ttcggatcga atttgtatca tttggtttta aatacgggtt
    17341 gccgatcgat tcggatattg tgatggatgt gcgttttttg cccaaccctc attatatccc
    17401 ggaactaaga ccattgaccg gaaaagatca gccagtctat gattatgtga tgtcctttga
    17461 tgaaacgcaa tcattctacc ataaattttt ggatcttctg gaaactgtat tgcctggata
    17521 cattaaagaa ggaaaaagca gcttgacagt tgcaatcggc tgtacaggcg gtcaacaccg
    17581 ttctgtggca ttgactgaac gtttggcaaa tgctttaggg aaaaactata aagtcaatgt
    17641 gacacatcgg gacaaggata aaaggaaaga gacggtgaac cggtcgtgaa aatgaaaacc
    17701 taccggataa gaaaaccaaa gatcgtagtg gtcggcggtg gcactggtct gccagttatc
    17761 ctgaaaagtt tacgaaatca aggagcagat atcacagcag tagtgactgt tgcagatgat
    17821 ggtggaagca gcggtgcaat cagagaatcg atcgctatgg ctcctcctgg tgacttgaga
    17881 aatgtcttag tggcgttatc ggatatgcca caattctatg aagatatttt ccaataccgt
    17941 ttcaaaaagg aagatcagtt tttagccaat catacgatcg gtaatctgat cattgccgca
    18001 gtttccgaga tgcggggaag cacttatgag gcgattcaat tattagcaaa aatgatgcat
    18061 gtagatggac atgtttatcc ttcttcagaa actcctttga ccttgcatgc tgtttttaaa
    18121 gacggaacga ctgcagtagg agaatctaaa atcgcgatca accgtaaaac cattgaccgt
    18181 gtgtatgtct gcaacacaaa tgataaaagt gaagccaaag cggctcgaaa agtcgtttca
    18241 gcaattatgg acgccgacat ggtcgttttg ggacccggaa gtttattcac cagtatcctt
    18301 ccaaatttag tgataccaga aatcggcgaa gcaatgctca agacaactgc tgaaaccgtc
    18361 tatatctgta atatcatgac ccaaaaaggg gaaacggaac atttcacaga tgccgatcat
    18421 atacgtgttt tacacaagca tttgaatcag ccttttatcg atacagtatt ggtcaatacg
    18481 gaaaaagtgc ctgaagatta tatggaccca gagatctatg atgagtatct agtacaagtc
    18541 gcacacgact tcaacggatt gagaaatgaa ggatgtcgag tgatttccac cgacttttta
    18601 gaattgaaag atggtggtgt cttccacgat ggagacaaag tagtagaaga attgttccgt
    18661 ttagttttcg gttcaaaata ttaagcaatt tattgttgga gaaaggagga gaataggatg
    18721 tcatttgctg cagatgtgaa gaaagaacta actggtttgg aagttcatcg agaacatgcg
    18781 aaagcggaat tagctgcttt gctgcgaatg aacggctctt taggtattgt gaaccagcag
    18841 tttattttga acgtccaaac agaaaatgct gcaattgcca gacgtatcta ttctcttttg
    18901 aaagatcatt atcaggtacg aagtgagcta ctcgttcgta aaaaaatgaa attaaaaaag
    18961 aacaatgtct atatcgtccg gttgaagcaa ggcacaaaag atgtgttgat ggatcttgat
    19021 atcatggatg gtatgatgtt caatggacac gtttcggacg agattatggg aaattcgcaa
    19081 aaaatgcgtt cttacttacg tggtgctttt atggcctcag gttcagtcaa taatccggaa
    19141 acgagtcgtt atcatttgga aatattttct atttatgaac agcataacca agacatttgc
    19201 gatatgttaa attattacgg tctacatgct cgaacgcttg aacggcgcaa tggctatatt
    19261 tcgtatttaa aaggagcaga aaaaattgct gatttcttaa cattgattgg tgcaaccaac
    19321 tcaatgctcc gatttgaaga tgttcgaatc gtacgggata tgagaaattc ggtcaatcgt
    19381 ctagtcaatt gtgagacagc aaatctgaac aagacgattg atgcggcttc taaacaaatc
    19441 gaaaacatcg aattgatcga agcaaaggtc ggtctacatg cccttcctga aaaacttcag
    19501 gaaatcgcag aacttcggct tcaacatcca gaggtcagct tgaaagaatt aggggaaatg
    19561 attccctcag gtgcaatatc aaaatcggga attaatcacc gaattcgcaa aataaatgaa
    19621 tttgcggaaa aactgcgtga agaagcagtt taatccaaag aaaaaactga tacatgaagc
    19681 aggagatgcg aatgtatcag ttttttttaa aagctatact tgcttttctt ccgtcaaact
    19741 ataattccaa ctttactgga gtaacataat gttgaaaggc ttctattgtt ttttaataca
    19801 atcgtataaa aagcggggag acaactgaat gaagatttta gttttataca taaacttttg
    19861 cttaatatag aagtcctgat atagatagga tcaagtattt atctataact ggagattaat
    19921 taaaaactgg aaggaactgc tcgatcaacc ttgagaactg tttttcttac ttctggtcaa
    19981 gattctcgtg gttggtggat aaggatggtt gataagttca ttggattagc tagtcgaaaa
    20041 caaccaggtg taattaatgt agaagtttta acaaggggat ggagtgattt attcagtgat
    20101 aatcataagt tcataaatag taattgggat gtatggttgg tatacgttat acctgaactt
    20161 gaactatcaa gatttggttt agaatttgag aatcgatgtt tataaaggga gggcaaaaaa
    20221 tgtgcttttt tacaactttt actatcatta tgattgcagt actttttatt tttctagata
    20281 tagcaaagcg aaatacagca tttttattat atcgggtttt acttcgagca ggtctcataa
    20341 catttatatc gatcgttgga ttttttctat tcacagttat tgtatttatt tggagaacta
    20401 cagcaccacc attgccagag attacatatg gagaatttcc gtttagtctt gaatatgaaa
    20461 tagatgagga aagaattttg attgaagata cggtgattgc agaatttata ggaagtttta
    20521 gagggaatgt gacaactcaa cctagacgaa gttggagtat aaaactttta aataatagtg
    20581 gagagttgaa agcatttcat tatgaattct taataataga aagtgaagat gtaacaatca
    20641 ctttaagtag tggctctgct ggatatttta tgaatgatgg tggaagcaag ccacagctca
    20701 cagtccgtga tcgtattgca ggttttatgc atttttctca ctatgactta gaagaagctc
    20761 gtaaaatact tgcagaatat gggatcacat taatcaattg ggaatatgcg ccaccgataa
    20821 gaaatttttt caatgattat tattagtctt ataaaaaaca gaatgtaaaa tttatgtgcg
    20881 cgagtattta gttttccatt ttttgtttga tagatatata gcattgttga agcatgggat
    20941 agtggtgcca attttatcaa tgaggttggt caggcagtta acataattgg tgatgctata
    21001 aatccattta attggaattg gaggaattag gtgtggaaac agtgagatta tggatattca
    21061 tgaaaaattt tcgttcggct ttgagaaatg ttattctgga atcaaaatca ggttattatc
    21121 tgattgacac agatcactat actttttggg gaggctacct ttttccgatt tttaattgga
    21181 taatccccca taaggttatg aaaattaact tgcctgcaga agaaataaat agattaatac
    21241 tcaacaaaga tttacaaagg aaaagagaga aagaacattc taatgttgct tggataggtc
    21301 cagcatttgc agtagtgact tcttcaattg tcggtcctat gctagagagt atttatagtg
    21361 atttttctat tggaatacgt tatttatttg ttactttaag tatagctgtt cttttgtgca
    21421 taaagggtta tgttagcaag aagaataaag atattttaac actaatcggt gtaaacaatt
    21481 tatctagtac taaaattata ctgtttcctg aatctataaa agaaggatca aggttgttga
    21541 taatttttat aatgcttata ctgttttctg ttttatttgg ggtgatgttt ataga
//
LOCUS       DAFBSV010000049        21500 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.050, whole genome shotgun sequence.
ACCESSION   DAFBSV010000049 DAFBSV010000000
VERSION     DAFBSV010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21500
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.050"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            2..400
                     /locus_tag="LLB18_001676"
     CDS             2..400
                     /locus_tag="LLB18_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBK5244678.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            384..1079
                     /locus_tag="LLB18_001677"
     CDS             384..1079
                     /locus_tag="LLB18_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBK5244679.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1663..2550)
                     /locus_tag="LLB18_001678"
     CDS             complement(1663..2550)
                     /locus_tag="LLB18_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBK5244680.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2735..3574
                     /locus_tag="LLB18_001679"
     CDS             2735..3574
                     /locus_tag="LLB18_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBK5244681.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3770..4744
                     /gene="sgrA"
                     /locus_tag="LLB18_001680"
     CDS             3770..4744
                     /gene="sgrA"
                     /locus_tag="LLB18_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HBK5244682.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5042..5398
                     /locus_tag="LLB18_001681"
     CDS             5042..5398
                     /locus_tag="LLB18_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244683.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5401..6558
                     /locus_tag="LLB18_001682"
     CDS             5401..6558
                     /locus_tag="LLB18_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5244684.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6584..7024)
                     /locus_tag="LLB18_001683"
     CDS             complement(6584..7024)
                     /locus_tag="LLB18_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBK5244685.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7184..7690
                     /locus_tag="LLB18_001684"
     CDS             7184..7690
                     /locus_tag="LLB18_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBK5244686.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            7858..9771
                     /locus_tag="LLB18_001685"
     CDS             7858..9771
                     /locus_tag="LLB18_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBK5244687.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9776..10777
                     /locus_tag="LLB18_001686"
     CDS             9776..10777
                     /locus_tag="LLB18_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK5244688.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(10979..11185)
                     /locus_tag="LLB18_001687"
     CDS             complement(10979..11185)
                     /locus_tag="LLB18_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HBK5244689.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11831..12679)
                     /locus_tag="LLB18_001688"
     CDS             complement(11831..12679)
                     /locus_tag="LLB18_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBK5244690.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12678..13745
                     /gene="gnd"
                     /locus_tag="LLB18_001689"
     CDS             12678..13745
                     /gene="gnd"
                     /locus_tag="LLB18_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HBK5244691.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            13747..14748
                     /locus_tag="LLB18_001690"
     CDS             13747..14748
                     /locus_tag="LLB18_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBK5244692.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14745..15029
                     /locus_tag="LLB18_001691"
     CDS             14745..15029
                     /locus_tag="LLB18_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HBK5244693.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15062..15859
                     /locus_tag="LLB18_001692"
     CDS             15062..15859
                     /locus_tag="LLB18_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBK5244694.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            15873..16706
                     /locus_tag="LLB18_001693"
     CDS             15873..16706
                     /locus_tag="LLB18_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK5244695.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16724..17581
                     /locus_tag="LLB18_001694"
     CDS             16724..17581
                     /locus_tag="LLB18_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBK5244696.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17603..18112
                     /locus_tag="LLB18_001695"
     CDS             17603..18112
                     /locus_tag="LLB18_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5244697.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18149..18550
                     /locus_tag="LLB18_001696"
     CDS             18149..18550
                     /locus_tag="LLB18_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244698.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18662..19015
                     /locus_tag="LLB18_001697"
     CDS             18662..19015
                     /locus_tag="LLB18_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244699.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19049..19492
                     /locus_tag="LLB18_001698"
     CDS             19049..19492
                     /locus_tag="LLB18_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBK5244700.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19509..20594
                     /gene="uxuA"
                     /locus_tag="LLB18_001699"
     CDS             19509..20594
                     /gene="uxuA"
                     /locus_tag="LLB18_001699"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBK5244701.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLEEHYE"
     gene            20587..21300
                     /locus_tag="LLB18_001700"
     CDS             20587..21300
                     /locus_tag="LLB18_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBK5244702.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
BASE COUNT         7399 a         3301 c         4489 g         6311 t
ORIGIN      
        1 gatgacgatc tttgaaacgg ttgtaacaga tgttggtata gaagcagaag tattcaggaa
       61 agaaaaaata atgattttat ttggagatga agcaccggaa acattaacag attattgtta
      121 taagattgaa ttgaatcagg taagaaaaga aataacttgt gatatgaagc tctgttttga
      181 taaacaaatg tatgtaatca cagcagtagg agatgttgtc caaactaatt tgaatgaatt
      241 aggacatatc acgataaaat ttgatggatc tcatgagccg gaacttccag gaacaatgta
      301 tgtagaagat aaggaaatgc cgcatttaag aaaggggaca atcattaaaa tcgatcaaga
      361 ggatcagaat gggggaaagc tatatggaaa tcatgcttga tacagcaaat acaaaaagta
      421 tttattcttg tcaacagttt ttgaatttaa caggcgtaac aacaaatcct acaattctga
      481 aaaaagaagg agcgtcaaac ttcttctcgc atatgaaaga aatcaaaaaa ataatcggac
      541 agattcctat ccatattcag acaataggaa gaacggaaga agaaatgata gaggatgctc
      601 gagttatcat agaagaactg ggaaaagata cgtttatcaa ggtgccggtg aatcaagcag
      661 gccttcaagc gatcaaaaag ttgaaaaaag aaggttattt gattaccggt acagctattt
      721 acacagaatt acaagggtat ttagctatta ataatggagc agattatatt gcaccttatt
      781 ataacaggat gcaaaatcaa ggcattgatg ctatgaaagt gattgattcg ttgcggactg
      841 agatcgaacg tacgcaaaga ccaacaaaaa tattagcagc tagtttcaaa aattgtgaac
      901 aagtcactac agccattcga tctggagctc atgcgataac gttaggtaaa gagctactag
      961 atcaagtatt agagatgccc tcgattgata aagcagtgag gggcttccaa gaagattggg
     1021 tgcaaacttt ccaagcagaa acgattggtg aactaaaaaa ggtcgctgat tacttctgaa
     1081 tcaatttctc cataaaataa acgatagcct tctcgaaaac tcgaggaggc tatctgacga
     1141 ttcaatattc attaatttaa agtttgggtg actattactt atttctcatt taaacgatgt
     1201 attccctaac ctctaataca tccttgtaac tctgaagtta cgccagtttt gaataaattt
     1261 cataaaaaca aatgaaaagt gtcgcataaa aatatctttc gtgtttctct agtataacag
     1321 aataagagga acaagtccag aagggatatt tttagtcttt tttaaaataa cttttcagtc
     1381 gagtttgagt ttatgatagt tgtttttgaa gcgatacggc aagtgaaaaa atagggaagc
     1441 atgaaagaat ctacttaatg gcgcattgat tcatgtgata gaaataaaaa acttttttaa
     1501 attatatcct catgattgta acaaatccag tgatttgttt tggtacaaat aaaaaaaggc
     1561 cccgatgaag ttgtggcaaa agtggtttgc ctcaaaaata agaaggaatt tccaaaaatc
     1621 acttctcaaa ttttgccaca tccccaattg ggtcaaattt gtttatttga atatattttt
     1681 tacataagga tctttaatag ttacattgtc ttttttcatc actttacgga ttgttttatc
     1741 catgaattcc gtatcaagag tttttgcttc ggtagcaatt ttttctagct cagatttgta
     1801 tttgtcttta ttagaacctt tatcctgttt ttttaccatt tttactagat aatagctttg
     1861 ctgataagtc gttggatctg ttacaggaat gatatcagaa acttccccgt tttttagttt
     1921 aaatgctgct ttttttactt cagtaggaat ctctggattg gttgaatcaa aattcatttt
     1981 tccatcagtt tcctttaatg ttttattttt tccataagct tgaacaagct tggagaaatt
     2041 ttccccttca tttgcttctt tttttgcttt atctgcttct tctttagtcg aaaatagaat
     2101 gatctgtgta ctaacttctg gatagaattc tttccaagca gtgtctagat ctttatctgt
     2161 taattttaca ttggctttca aaccgtattg gaaagccagc atctgtttaa agagtttctt
     2221 atatgtctct tctgtttggc caactgcttt taattgttcc ttgtagtttg gaccgagttt
     2281 tttgatttgt tcattatatt cttttgttac ttcctttgaa gaaatctctt ttccgtatac
     2341 atcatcaaat gctttgaaga caatcatttt ttttaatagt gtttgattat ttgatttaac
     2401 ttttgggtta tcataaaaat cctgaactgt aagtgttcca cctttaaacg ttgcaatcgt
     2461 ttcattggac ttgctacaac ctgagaatag taaaattgca catgctgaaa ggcacataat
     2521 tagtagttgt tttttcaaaa aatttcccat cctttcctta ttaaaaacag tctaacagaa
     2581 gaattaggga gacagtcttt cattttcgta aggttgctgt agatattctt agttcgtaaa
     2641 aatctattct ctctatgatg gagaacattt acatagtttt cacgagacaa gaaagaaaag
     2701 ggttgttaaa cttaatataa aggagggatg aaagatgatc aggattattc ggttgattgg
     2761 atctgtttta atagtcttag ttggttttgt tttaggaatt cttgtcaata atgcacttgc
     2821 ggatatgttt attggaaata gtgaatggat tggagcaatt gccggtacgg tcggacattt
     2881 agctgttttt ttactagctt tatttcttgc tagtaaggtc gaaggaaaaa gaatagaaga
     2941 ttatggtgtt tctgttcgag gaaaagactg ggggtattta gcgggaggtc tcgttgttgg
     3001 aattggagtg tttctgctta ttactagtcc attatatttg acgggggcgt atcggttaga
     3061 ttcaggaaac gcaaacattg tgccgctgat aacgagtttt attttattta ttgcagtggg
     3121 ggcatcagaa gagcttttat tccgtggctt ttttcagcat cagatgctta gatttggtcc
     3181 gttaatagca atgattggat ctgctgcatt atttgctctt ttgcacggat tgaatcctaa
     3241 catgacattt ctggcagttt tcaatatctt tttagcaggt tgctttttca gcgcacttat
     3301 ctacagtaca ggaagtttat ttacggctat tggtgctcat attacttgga attggacaca
     3361 aggagctatt ttgggtatac cagtcagcgg aacgcaagaa caaggttttt tctccactct
     3421 gatccaatcg caaaatacaa taattactgg gggaaacttt ggggctgaag catctatatc
     3481 aactacatta ttcttgttag tcttgattgt tggtttgtta ctctatgcat ataaaacaaa
     3541 gcggatgaag aaatacactg ctgtttatca ataaaagatg aagaaagcaa ggctgatatc
     3601 ggtcttgctt ttttaagtct gtcattgatt aaacgaaaaa gtaaacaaat tcaagcgaat
     3661 acacgacatc ttttgttaga ttttcacaac tgactgtcgt gttctcatca ttttcatttt
     3721 atataattcc tttatcaaat agaaggtaat tatatggaga gtgatagaaa tgaagaaaac
     3781 agcgaccgta ttatttgtta ttcttgggct gagtataatt gcagcaatga ttggaatcag
     3841 tacttctgca aatgaacggg caaatgagaa tctttcattt actgtgaaaa ctgatcggat
     3901 tgtttatgac atgacacaac aagtcattac tattccagtc aaaccaaaca aaagcgtgaa
     3961 tgctagtgat gtacatgctg ttctaacata tggttgggat ggtaatggaa gttcagaaaa
     4021 agttattggg gaagtttatt taaaagacgt acaatggacc gctggtattg agtatacaat
     4081 aatgatttct gcagaactat cgattgatga gatcaagagt aaagataaag ttgatttgat
     4141 tgttttttat gatggacaga tgacgatcac ggagaatttg aaaccaagca gttggacagt
     4201 tgttggaccg ccaagcagta cggatagcac aagtagtgaa agcagtacag aaaacacgag
     4261 cggtgaaagc agtacagaga gtacgagcag tgaaagtagc acagaaaaca cgagcagcga
     4321 aagcagtacg gagagtacga gtagtgaaag tagcacagga agcacgagca gcgaaagcag
     4381 tacggagagt acgagtagtg aaagtagcac aggaagcatg agtagtgaga gtagcacagg
     4441 aagcacgagc agcgaaagca gcacaggaaa agtaaataat gaacttgatt tggtacctat
     4501 cataccaact aaggaacaaa agagaaatgc agggagcaac ctaaaaagtg tgctaaaaca
     4561 gcctgatttt gtttctcgtg gaattgatca tcaagaaaaa gcgaaagaaa cagataatag
     4621 aaaaagcgat ttaccagaaa ctggtagtag aaccttgaac aagctaatta catggatggg
     4681 tgtgttactc attttgattg taggagcaag ctattttcgt tctctcttcc atcgagtgaa
     4741 ataaagaata aaagcaacag atctaaaatt gaataaaacg atagattttt gagtgaatat
     4801 ttcattcgag agtgctgtat tgcctggcga agttgtagct ttgccagatc tatttttgtt
     4861 tactaacata tttgagaaac aggaaataac aggaacacaa atggaaaata agagcaagaa
     4921 taattgacaa tgcacactgc gcatggtagt atctctgaaa aatcagtaac gaatctattt
     4981 gtacgttatt catgtagctg tcggaataag tctaaataat agataaaaag gagtatgtac
     5041 tttgtttgaa gaatttattg atatcaatga aaggcaagta tatcaatttt tgaactattg
     5101 ttatgaaaga gacgagaaat tatatgtggt gaaggatatc gctttagatc taaactacac
     5161 cctggctaag atgaattcgg tgattcaaca agcagaatcg ttttgcgaaa ggtatccaga
     5221 atataaatta tcttttcttt cagaaaacaa gatgataaaa gtcgagtttt cttctcagtt
     5281 tttactgagt aaagtttatt ctatactttt agagggaacg attggttata ttttactgga
     5341 ttcactttac aaaggtactt atcaatcctt agaaaatctt agtcaaaaaa ttatataagt
     5401 ttgcgtacga ttcaaagaaa attaagagaa cttaatacta ttttgaaaaa ctatcattta
     5461 tcttgcagct tgaaaaaagg taatccgata gaaggagaag aataccgtat ccgatacttt
     5521 tttcacttga tgtattggca gtcattcgac gaaaatcatt ctgatatatt atcaagtata
     5581 aaaaataaac gtcaactatt agaaaaattt gcgaaacatg cgccatatac gcgtagtata
     5641 gatagaaaga aatggatcag cctactaaga atttcgttgc aacgaatgaa acaaggccac
     5701 tcgattacgt atgtcccaga agagatgaac aaatttgtgc atccattgat aacaaaagaa
     5761 gagtttacgc attacatact agagcctttt tttgaagcaa acttctggtc gatgaatcac
     5821 atcactccaa cagagcaagc ttacctttat tttatgtttg gtgtaatgaa cacctatttg
     5881 gaagaagatt tgttggatac tccagataaa gtacaagaaa gttggggctg gattgaatcg
     5941 tctattgtag aaaattttga aaaaaacttc aagatttgtt ttacaacttc agaaaaaaat
     6001 tatctatatg tcaatttggc aatgatccat ttgtattcaa gggtttttgg gacaaaaaag
     6061 aaggtggatg cttttggaaa atcagcagaa gacagagatt ttcagcatat atttccagtg
     6121 atgtatccaa tcatgcaaca gttttttagt ggggtagctc gcagaattcc agagcttaat
     6181 acttattatg aaaagaacag acggttgatt tttcaatact gtatgttagt cagggatatt
     6241 tttataaaac acgaacaacc tgtcatattc tatattcaat caaagtatgg taaaacacag
     6301 gaattatggg caaagaaaag gatattatct atgactgaac gcccaataaa atatagtgca
     6361 tccgctgatc agttacctga tattgtcatt agcgattatc ctatcgacaa aaaggcatat
     6421 gatcaaacga atacacagat attttactgg aatggacaac ctacaaaaaa tgattgggcg
     6481 cgtctgaaag ctgaaatcat aaaaatcagg aatgagaaaa atagatccat attggaaaaa
     6541 ttggatttcg ttaattaaga aaagcagatt gtttatgcca aaattaagac attgcaaaaa
     6601 gattattttc tttaaaatcg acaagatgac cagaaagcaa gagttcgttg agctcttgct
     6661 ttcttttagt tttagaaagg aacatcctga ttttatcttc gctaaatcca gtcaaaagtt
     6721 ttgcagattg gtcgtagata atcggttttt tcaataaaga aggggatgta cgaatctcaa
     6781 tatatagttc actcaaactg agttcatcta ttctgtgaac aagattttta taactaatag
     6841 aatgagtaga gagcatttcg gtcacgccgt tgtttgtcaa ttttagtaag tggataaatt
     6901 catttttggt tagtggttga cgaattaagt tctgttcgat aaacggtata tcatggacga
     6961 taagccaacg ttttgcgcgt cttgaagacg agcagccaga acctgtatac aatttaatca
     7021 tcatacattc ctccaatagc taagtattta tgaaataata acatgaagaa atagtcgaaa
     7081 agtgccattt agaggtgtaa aataagaaaa tgttgtcacg tataatggaa ctagctagat
     7141 aagaaatact attaaatcaa gaaaaaagaa agaaggcaca agtatgtcaa acacagccga
     7201 cgcaatagta gtgatcgatt tacaaaaagg ggtatgtttt gattcttcgc cgatacacga
     7261 attagaaaca gtgacagcat tagtgaataa aagaatcaaa acatacgaaa cgattgggaa
     7321 accagttatt ttcgttcaac acgaagatgc tcaattagtg ccacaaacaa aaccatggga
     7381 gctattgtcg gaattatcta ttcctgagca cagttatttt gtgagaaaaa cccatgcgaa
     7441 ttcattttat aagactaatt tgagtgtttt attaactgaa ttggactgtc attcgatcga
     7501 attatgtggg gcacaagcag agtattgtat agatacgact gtgaagtttg ctcatggatt
     7561 aggataccag cttatgatgt gtagaggagc aacgacaact tatgataatc cttttatgaa
     7621 agcaaaggaa acaatcgctt tttacgagaa aatttgggat aaacgatttc tgacattttt
     7681 ggagcaataa gttgtttctt cgtttaaaaa aagcagaatg gatactggtt tatccattct
     7741 gctttattac gtaaaatgag aaaataatcc tgttctattt ttatgggata aaccatttat
     7801 tttttgtata aaaaatgttt gcgtttacat ataattctcc tagaaacata aaaaggagtg
     7861 aatagcttga gaacaaaaca agtattaaag ggagcgttgg tcatcttatt tgctgtaagt
     7921 acaagcgtcc cgcaatggac agtatatgga gagagcattt cttccgaatc ggaatctcgg
     7981 gaggtagaaa ccacagaaac tactgatgct ggaaatgaaa cgaaatcgag tacttcacaa
     8041 acagaaacaa atactgaaac aacggttgag acatctgtta ctagcacaga tcaagaaacg
     8101 accgctacca cagataacca acaaacagaa gaagcaacag ctacaaaaat gtcaaacgac
     8161 gaatcctctt ctgctaaagt aagtgacaaa gagaatggga cagaaaatga tgatatcggt
     8221 aaaggtgaaa atttcaatgg taaagaatat ttgaattact tcggtaaaca gatgacagaa
     8281 atacttaatg gaccaacaga agacatcaag tcaaaattaa tagagttatt agtcactgag
     8341 cttgctgtta atgattatgg tgtagataaa gagattatca aacatctgat tgctacttat
     8401 ctattgtacg atatcgcttt tgcaaaaaac agtgtgttga tgtcgatgct tggaggtaca
     8461 gatgatggga caacgcctac agaaaacaca ggcttctatc caaatacaaa acaacttcat
     8521 caaactgtac taaacaaaca agatggcaaa atgatggatg tatatgcata ttatgtcgat
     8581 caaggttcag ataaaacagt catgatccat ggcggatttc gagggaattg gaataacggg
     8641 atcgttacag aagaatacaa tgatttttat aaggccgggt ataatttatt atttgttgat
     8701 tccagagcga ctggtaatag cggaggcgat tatgtgacct atggacaata tgagtcagat
     8761 gacgtccttt actggataaa tcaagaagtt cgagagcggc catctcaaaa gattttactt
     8821 tatggtggtt cgatgggagc agctacgatg atgtctgtat tagcgaaaga tattcctgtc
     8881 aatgtcaaag gaattattga aaattgcgga tttgcatcaa ttgatgaaca actacgtttt
     8941 acgtacagcc agacagtagc ccccgcacta ccggatgcca taaaaaatca gttagacatc
     9001 attggggatc aagagcatga agatttattt atgggccttt tgaaacaata ctattttgat
     9061 caggagatgc atttggatac aaaagctgct ctacctacga ttggaatgtc agattcattg
     9121 cctaaattga ttatccatgg aacagcagat gatgtagtac ctgtgtctaa cgcgcaaaaa
     9181 ttatatgagt tatcaggagg gtataaagat cttttattag tagaaggagc agggcatgga
     9241 aaggcacagg aagttgacca tgctgcctac acgaaacatg taacggactt tttgaaagta
     9301 gtgttccatg atcagataaa cgtaaagtat gtggatgaaa acaataaaag tctactcaaa
     9361 gaccaggacg aaatccagct ttacggagct tatggagaaa attatatgac agagcaaaag
     9421 acattcgaag gatacgaatt agcaaatgtt gaaggaccga ctgaagggat ttttaatgag
     9481 acgataccaa ctattatttt ctattacaaa aaaatcccag tagctccacc aaaaaagcaa
     9541 gatccgacag agaatgcaga caataaggga aagaatgaac ctcgagagga tcaatcaagt
     9601 gatgatacgc aaccgattca gatgacagtg aaagtacaaa aaaagacaga tgcaaaaaaa
     9661 agaatgttgc cgaaaactgg agaaaagaaa cattcgcttc tcatttattc aggtggattt
     9721 ttatctgtta gcacgattat cacatggatt tggcgaagaa agagagggta aatgaatgaa
     9781 atggttcaag cgaatagtga ttgcagtacc agttatcatc gtagttattt tagtcactgt
     9841 atttttgatt aatcaaatca caccaaagcc gattagcttg cttgttagaa aacaatttga
     9901 cacaagtgaa aaagaacaag tatatgcccg accagatgat ttccagcaaa aaatcgaaca
     9961 aatcgatata aaaaaagaaa tatcctatcc ttcaaagtac aaaaataata atatggatat
    10021 ctacacaccg aaagtggaaa agaaaaaatt accgattctt ttctggatgc atggaggcgc
    10081 atatgtagga ggggataaaa atgattgtcg tgattatttg gaatatctat gttcagacac
    10141 gcagcaaatc atcgtaaata tagattatga acgatcaccg gaagcaaaac atcctacacc
    10201 agttatccaa ttgaacgaag ccattcaagc agctaaaaaa gagataaaag atcaagcaga
    10261 ttggtcgaat atttcgattg gtggaaattc ggcaggtgca caaattagtg gagaatattt
    10321 gttagcactt caaaatgaag aaattaaaaa agctgatcat cttgatccga ctttggagaa
    10381 caagcagatt acgaagttta tttctttgtc tggtctgttg gatccttctg cacttactca
    10441 agtaagtgat aaaatctcta gctttcttta tgaaaaatgt ggatgggctt actttgataa
    10501 taaggacttt gaacaatcag agaaggtcaa aagtttagcc ttggtcagac atgcggatcg
    10561 ttggacgcaa aacacattct taacggatgg aaatacaaat acgtttacga aacaaatgga
    10621 agaagtaact tctgtatttg agaaagcggg ggtgaaagtc acaaaagtag attatgcgga
    10681 gaaaaatgct gttttgaacc atgaatatca gtttgatttc agcaataaac aagcgcaaga
    10741 aacatatcaa aagttagtaa tgtttttcaa ggagtaaagt cttatgatgc aaaagaggtt
    10801 gtaatctgtc acttagctcc aagtcacaag gagcaatttc aataaacaag cttttcatgg
    10861 tttatgaata ttgtaacttg tgactgagga gttagagatg gcaaggggca ccttttattc
    10921 gaaatttggg aatatcacac gattattgtc acgatctctt ttacgtaaat tttataagtc
    10981 agatttgttg ttttgatcgt ttaaaaaaag caacaaatcc gaagcctgcg gaggcaagaa
    11041 gggacaaaaa gccgagtggt aagcaaaaga atgctggttc cactaatatt ccgttgttat
    11101 tgatataagg ctgggaacaa agatgaatag caaataaaat caatgcacta gcgaaaaaaa
    11161 gcaaagaaat atggatagct ttcataagca gcacctcctt ttttataatt gtatgataaa
    11221 tagattaaga atctataaat gtgacaagtt tgttaggatg tgaataaaat gatcatctag
    11281 cgaacttgaa acaaagatgg ctaatgataa gcaattaatg attcagcaat cagataggta
    11341 caaagtttac catcatacgt ctagaccaat aatagaaaat atgggaatat aatagaaaag
    11401 atttaggata cccccaaaag aatttcccca aaaattcgat gtatcctaaa cttttttatt
    11461 ttacataaca atcatatcaa ctgtgaaata aaattacaaa tgataaccta aaatgaggcc
    11521 aaaagccagt gttatcaagg aaatacttaa ttcaccaaaa ttttttttaa ttttttagaa
    11581 aataagaaac aaaaataata aaaaaaagaa aagataaatt ttttactact gtatactaac
    11641 tttgttatcg catctaacaa gtaactcgaa taataccaat acaaccttct ccaaagatgc
    11701 gatgacatac gttctaaccc accgactatt gatgttctgt accacccttg cagaaccaaa
    11761 aaagccacta ccaaatattt ggtagtggct ttttttgttt tatggatttt tcgctttttc
    11821 tgttatggtg ctattctttg atttcagaaa tagtatgtcg aactttagcg atagaacgac
    11881 gtgattcttt ttcgttgtaa aacatcaaaa tcacatatag agagtccaaa atgcttagtt
    11941 gagaaatacg ggaagctaaa gcttcagatc ggaattctgt ttcttcagaa atagaaataa
    12001 aaacgacatc gccaagttta gcaagggaag aattagcttg gctagtaata acgattgttt
    12061 ttgctccagt ttttcttacg gtttcagcaa tatggattgt ttcttttgat tgccctgtgt
    12121 gagaaatcaa aacagcacag tctttttccg tcaataaaga agcttccatc aattgaatat
    12181 ggtaatccgt gctgtgagaa gttgcgatag gggaacgcaa aaatttatga taagcgtcag
    12241 ttgctacaat ctctgaaccg ccaacaccga aaaaatagac acgtttagat tcattgataa
    12301 tagtagccgc tttttttaga tccttttgtt gtaacaactt ttttgtgtca tttaaagttg
    12361 aaatactaga ctcgaacacc ttttgcgcca tagtgagctc agtatctgtt ttctgaatat
    12421 tttcgtggat agaaatagca gatagatcat tttcttggat caacatggcc attttaaaat
    12481 ctttaaatcc attataacca agtttttttg taaattgaaa aaaagtagag tcagcaatgc
    12541 ccagttcact tgctaaattg ctaataggac tatgacttac tttgcttgga ttttctaaaa
    12601 tataatcggc gatagcctgt tcttttgggc tgaagtcgtt gtacattgtt ttgatttgta
    12661 gtcttatgga gacgctcatg agaattcctc attttcataa taagattatc attttttccg
    12721 ttctcattaa tgttaaagat acaaggagag taggaaaaaa tcaaacaaaa aatatttttg
    12781 taaaatctat ttacaaaaaa atttttttgt ataatgaggg tataagaaat ggaggcgcta
    12841 tcatggaaat tggtgtaatt ggtttgggaa aaatgggatt gaatttagct ttaaacttaa
    12901 aagagcacca tcacaaagta caaggactcg acatttcaag tacagctgtt agtcaggcaa
    12961 gagaaaatga cattcctgct tatcaagaga tctctgaatt tctagctact tttgagcaga
    13021 aaaaaatcat ctggttaatg cttcctgctg gagagataac cgaaaacatg ttaagaaaac
    13081 tttttccaaa actcggacca ggagacatta ttattgaagg cggaaactct tattataaag
    13141 attcaatccg tcgagcagaa gagtttcaga aaaatgaaat cggttacttg gattgtggga
    13201 cttctggagg aatcgaagga gcacgacatc aagcctgctt aatgattgga ggagataaag
    13261 aaacttttct atccgtggaa caattattca aagatgtagc aattgaaaga ggatatctgt
    13321 atgctggtgc atccggaagc ggacacttct tgaaaatgat ccataatgga atcgaatatg
    13381 gaatgatgca agcaatcggt gaaggattcc aacttgtaca aaaaagtgag tatgcttttg
    13441 acttggaaca agtcgcacgt gtttggaatc atggttcggt gattcgcggc tggctgatgg
    13501 aaatcatgga agatcagtta aacgaacatc ccaatttaag taattatcgg ggaatcgttt
    13561 ctgcatcagg tgaagcaaaa tggacggttg aaacagcgct agaaatggct gttccagttc
    13621 cagtaattgc aactagtttg ttcatgagga atctttcaca ggaagaagat agtttttcag
    13681 caaaagtagt ttcagcacta agaaatgggt ttggcggaca tgaaatagtt gaaaagggtg
    13741 agtaaaatgc cagattatca tatagcaatc gttaattcca gcagtttcgg aagagtcttt
    13801 ccacaccact tggaaagatt aaagtcagtt ggagacgttc atttctttac tgttgatcaa
    13861 gagattccag gaaaagaact agcggagtta cttaaaggat tcaatatcat tattgcaagt
    13921 gttacgccat tttttcgacg agattttttt gaaaacaaag atgaactgct attgatttcc
    13981 cgacatggta ttggttacaa caatattgat ttaaaagcag caaaagaaca ccagacaatc
    14041 gtatctatca tacctgcttt agttgaacga aatgctgtag cagaaaataa tataactaat
    14101 ttgttgtcca tgcttcgacg cacgacacaa gcacaagcaa gagtcaagga cgatcgatgg
    14161 gaagatcggg cggagttcgt cggtaggacg ctgtttaaca aaacagttgg tgtgattggt
    14221 gcaggaaata ccggaagcgg agtaatcgaa attttgcgta acggttttcg ctgtgatgtt
    14281 ctagcttatg atccttacaa atcagattta tacatcgaaa gctttggtgc aaaaaaagta
    14341 gaacttcaag aattactgga acaatcagat atcatttgtt tatgtgcgaa tttgacagaa
    14401 gagaactatc acatgatttc tgataaagaa gtcgatcaga tgaaagaaaa tgtttatcta
    14461 tctaatagtg caagaggcgc tctagttgat gaagaagcga tgattaatgg tctgaaaagc
    14521 ggaaagatcg caggatatgc cacagatgtt ttagaagaag aaccgggacg tcaagatcat
    14581 ccgtatttag cgtttgaaca agtagtgatt acgccacata tatcggccta cacaagggaa
    14641 tgtttagaag caatgggtga aaaatgtgtc agagatgtcg aacagatcag tcagcacctt
    14701 cttcctgaac gttctgtcca gacaaagagc aactatataa aaggatgatg aagaaaatgg
    14761 tgaacggttt aaaagtgaaa acaggccctc aattttattt atatgaagaa ggtggtattt
    14821 caaaagtttc tgatctcttg aaatcatacg gcgcgaaaag agtactggtc acccacggaa
    14881 cggtatcatg ggaaaaggcg ctacctaaat tagtattttt gaatgacgaa acgattcaat
    14941 ttttttatca tcgttattct ggagaatgta gttatgctga agccagacga atagctacaa
    15001 tcatcaaaaa aatgaaatcg atttcgtagt tggcgttggc ggaggaaaac tgaccgatct
    15061 agtgggttat agtgccaatc ttgcaagaat cgatttcgga gtcatcccta ctttagctag
    15121 taattgtgct ccatggacac ctcttgctgt catgtataag gagaatggac aagcagaagg
    15181 gaaaacagaa cacttttaca gacaagctgc tttttttata acagatcccc aattagtgat
    15241 tgattcccct gttccatatt tcattgccgg gttagcagat acactagcaa aatggtatga
    15301 atctgagctc atcttagaac aagatttttt gcaagatgaa tcatttttga agctagcaca
    15361 agatactgcg aagatctgca aagaagagat tttgaatcat tctgctaaag caatccaaga
    15421 tatggcacaa agaaaactga catcggagtt caaacagctt tcagagatta tctttgctgt
    15481 tgctggttta gttggaggat taggagataa atacgcaaga aatgtggcag cacatgctat
    15541 gcatgacgct atcagtaaat atattccgga aagccatcgt tttctacatg gagaaaaagt
    15601 agcgtatggg attttctatc aactggcact agaaggtcgc tgggaaaaaa tagacgagtt
    15661 atatcctttg tatcgggaat tagaactgcc ggtttctcta gaacaaatgg gattatttcc
    15721 gaaagataaa cagataatag ataaaatggc tgaatttatt gattcgaaag agaaagtgca
    15781 tttgattcct atagaggtaa cacagaaatc actgatacag tcaatgatgg aactggaagg
    15841 ttatatcaga aagatctgaa ggaggaggac acatggaaac attaagtgta gtacaaagtt
    15901 tgttgattgc tttatgggta gccgcggtta tgtcccgctg gttaggtgga ggagccacgt
    15961 tgaccttacg tttttctcct ttgatgactg gattagtcgt cgggttgatc atgggggaag
    16021 ttgcacaagc gatgattgtt acagccgctt tgcaaatgat ttatatgggg gttttttctc
    16081 caggaggatc aatgccagct gaaccatcta ttgcagcagc tatcgcagta ccagtcgcat
    16141 tattagggga tctgtcgcca gaagcagcga ttgccgttgc ggtgccagtc ggattgctcg
    16201 gaagttactt gtatcagttt cgttttttca tcaatacttt tttaggtaaa tatacagaca
    16261 aagctgtaga agatttgaat acaaaagcta tggcccgatc aattattctt tatccaacgg
    16321 ttgcctcatt tttattattc gttccgcttg ttttcattgc tttatattta ggggcgccat
    16381 tgatcgctga tgtaatcaaa gctttagagg gaacagtcgt tatccacatt cttgaagtag
    16441 taggtggagg gttagcggca atcggtatcg cgacaactgt atacgttatc ggtcgaaaag
    16501 attatctggt ctttttcttc cttgcttatt ttatgagtgt tgttttgaaa tctttagata
    16561 ttacgatggt tacttatgcc atttttggga ttattatcgc tttgatcttt gtccagtcgc
    16621 aaaaagggaa acaagtacag cctgccacaa gcaataacaa ttcagcatct tttgatgacg
    16681 aagatgacta tgatgacgga ttttaattta ggaggaatgg gaaatggctg aaataatgga
    16741 taatcaaaca ggtgctcctg aagaaatcac gaaaaaagat gtaacaaaag cctatctgag
    16801 atggcatttt gcaaacgaaa ttcctcactc ttttgaacgt tacttggcgc catcactact
    16861 atacggaatg atgccaatct tgaaaaaact ttataaagat gaagactctt taaaagcagc
    16921 atataaacgg cagttactgt tcttcaacac tcaattaagc tggggtggcg gtgtgattac
    16981 tggcctaatg tcttctatgg aacagcaaag agcagaagaa gagtatgaag aaaaagagat
    17041 cttgatgcag gatgacttga tgtataacac gaaagcggga ttgatggggg cactagcagg
    17101 aatcggagat gcaatcgatt caggaaccgt ccaatatatt tttatcgcaa tcgcggtacc
    17161 ttgggcacaa cagggaagtc ctttaggcgc actttttcct tttatctgct ttgggttgta
    17221 tcaggtttta ctaggggtat ttttcgcaag acaagctttc actatgggcc gtaatgctac
    17281 aggcctaaag caaaacactg gtgttcagac agcgattgaa atgctatcag ttttagggtt
    17341 gtttatgatg ggggtgcttg cgggaaacta tgtaaaagta gaatcttcat tgaaatttgc
    17401 gatatccgga cgtgagtttg ttatccagga aattcttgat caaatcgtgc cagggatatt
    17461 acctttagct gtcgtaatgg gtgtgtactt gttctatacg aaaaaaggat tgaaagtcac
    17521 acaagcatta ttatggctga ctggaatatt aattgtgcta gcaggaatcg gtattttata
    17581 aaaagaaggg aacgtgaata agatgggtgt agtcaattta gcgcgtgtgg atgagcgttt
    17641 gatccatggg caagtaatgg taacgttatc tcaaaaaagt ggagtgaatt ccatttttgt
    17701 tgtagacgaa gttgtagcaa aagataaatt tatgagagat ctttacaaaa atgcaggaag
    17761 ccgtacagga caaaaaacaa ttgtcattac accagagaaa gctaaattct attgggatga
    17821 atatcaattt aaagaataca attgtatttt gatcgcaaaa acagtccaaa cgatttacga
    17881 cttagtaaaa cacggaatcc ccatggaaga attgaatatt ggagggattg ctcaaaaaaa
    17941 tcctgataca gatcttttag tgacgaaatc tgtttattta aataaatcag atgctgaaaa
    18001 attgaaagaa atgaatgaac aatatggcgt aaagaatatt tattttcaag ccactccatc
    18061 tgcacctaaa acaggattaa aagatgtatt gaacaagttt gatttgtcat aaacaaatgc
    18121 ttagaaaaaa gataaagagg gcgaaaaaat gaagaagaac gagctgtttc gtgattggga
    18181 atttcgttat cgctatattt accgtaagcg ccgtacaaaa aagagtaaac agcgttttct
    18241 ttcagcatta gtatcagata tttacagtat gagaacagat gtgacagtca ttgcttacga
    18301 tacgctagcc taccgatcaa aaaatattta tgttggagat atcgaaaaag cagagaaagt
    18361 tatctgtact tattacgata cacccgttca tgcattagga agttatttca tgtttgattg
    18421 gaaagaccaa aggaaaaaaa caatctactc tatattattg tccttcattt tgttgttcag
    18481 tttaggttgg tggggaatga tgatatataa caaaaatcct catcacgtat tcgatctgct
    18541 atccgtataa acaggtatca ctgtactagc atttgggagc tactttttct tattgggaaa
    18601 agcagctcgc ggatggccta gcagacaaac ttttattcga aatacttcat ccatattaac
    18661 gatgctagaa atgatccgta cgattgatga tccgagtgta gcgtatgcgt ttgttgatga
    18721 aggctgttat ggagaaaagg gcttagacag cgtgagatcg ggtatgaaaa aagaggctat
    18781 tcttttttat ctagactctg ttggggcaga tacaccgcta cagttttcgg gaaattattt
    18841 ttcaaataaa gaacagtggc tgaaacaagt tgataagttg aaagaaaaaa acgtcaatta
    18901 tatttttagt gcaagaaaaa agcaagcgca gttcttctat ttgaccaaaa cagatttacg
    18961 agggaaaaca tttaattggc aaaatgccaa tcagattatt gctctttttc gataagtaaa
    19021 aagtgcaaaa caaggagtga gaagactaat gttggaaatc atgatcgtta cacatggtaa
    19081 gttgagcgaa ggactgaaag atgcggcgga agtaattgtc gggacatcga gccatattga
    19141 aacaatgtgc ttagagtctg gggaggacat ccaaacattc ggagagaagg tcaaagaaaa
    19201 attaactatg atcaacacag cagaacccat gctagtattt gttgatctaa ttagcgcaag
    19261 tccgtacaat caagcgctct tggcagtcaa tgaactgact gaagaaaaga aagcagccac
    19321 ttatgtcata gggggcgtga atctgccaat gttgttagaa gcaatcaatc atcagatgct
    19381 tcacacaccg atagaagaag cggtggaaca aattgtcaaa caaggaaaag ataatttaac
    19441 tgtttggcat gcttcagcgg aagaaaaaaa attagatgag gacgattttt agaaggaagg
    19501 ctgaaaagat gaagtgggga tttagatggt atggtgaaaa aggggattcg atcccattaa
    19561 aatatgttcg ccaaataccg ggaataaatg ggataattgg aactttgctg actaaaatgc
    19621 ctggagatgt ttgggagatt tcagaaattg aggagttgaa agcatctgtt gagagccaag
    19681 gactggaact gcttggaatt gaaagtgtag cgatccacga tgcaatcaag gcagggacag
    19741 atgaacgaga ttactatatt gataactata tacgaacaat caaaaacttg tctcgatgtg
    19801 gggttcgatt gatttgttat agcttcaaac caatttttgg atgggcgaaa actgatttgt
    19861 ttaatgaaaa caacgatgga agctattctc ttttatacga tcagaaaatc gtcgatcaga
    19921 tggagccagg agaaatgtat caattgatac acagccagtc aaagggattc aaattgccgg
    19981 gttgggaaga agaacggttg aaaaaattcg ctcagctgga aaaactgtat gaaggaatga
    20041 ccgaagaaga attatttgaa aatctgactt attttttaga aaaagtgatt ccagtgtgcg
    20101 aaaaagcaga tgtaaaaatg gctatccatc cagatgatcc gccatgggaa ctttttggtt
    20161 ttcctagagt gacgaaaaat cttggcgact tgaagaaaat tctaaatgca gtagattctc
    20221 catataatgg actaacgctg tgcacaggat ctttaggggc aaatccggaa aacgatttag
    20281 ttgaaatcat ccatgaggta ggttcgcgca tccattttgt ccacttcaga aacgtggagt
    20341 ttttaggaga aagaaagttc aaagaaacgg cacatccctc tacagaaggc tcccttgata
    20401 tgtatcatat tatgaaagcg ttggtgcaag aagggttcga cggtcctata cgccctgatc
    20461 atggtagaac cgtgtggggt gaagtggcta tgcctggata tggcctgtat gatcgtgcaa
    20521 tgggactcac ttacatgcaa ggtctatatg aggcgataag taaggaaaaa ccactggaag
    20581 agcattatga ataaaatcaa gctcttcatc tttgatatgg atggcctttt attagaaact
    20641 ggacgtttag cttatcgtgc ttatgtaaaa tcagcacaaa agtatgatta tgaaatgcgt
    20701 aaggaagtct attatttact aactggccaa acagaaatgg cgataagaga acaaatgggc
    20761 attttgtacg gagaagatgt tccatatatc aaatggcgag aagcaatcaa tcaatataaa
    20821 gaaaaaatcg tgaaagaaga taagagagta tatacgaaaa aaggagcaga agaaatttta
    20881 tcttttgcaa aagaaagagg aatccataca atcgtggctt cgtctaatac acgggtaaaa
    20941 gtagaaatgt atttaaaaat ggaaaatcta tatgccttgt ttgatcaaat catttcaggg
    21001 gatgatgtaa aaaaaggaaa gccggaacca gagatctttt tgaaagcttg ttcaaaaatg
    21061 aatattcctc caagtgaagc acttgtattt gaagactcga ttgcagggat cgaagcagca
    21121 aggcgagcgg gcattttgtc ttttctcatc aaagatcatt tgatagggtt gcccgatcat
    21181 aatgggaagc ataagttgaa agtagatgta agtttatatg aatccaataa agcagactat
    21241 gaattttatg acctgcatca agcaaaacga tttttagaaa gtaaagggtt gtatctctaa
    21301 taaagaggac tattttctag tcctctttat ttattgtcct gcacgactga gggaacagat
    21361 gaaaaagaag taatttttta ttttgaagta tctaccttat ttgtagtgaa caatttagaa
    21421 caaacacaaa acgcatctac tgttatctac cagtagatgc gtttaaagag aagaacgaga
    21481 atcgtccata tgagggtttc
//
LOCUS       DAFBSV010000050        21095 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.051, whole genome shotgun sequence.
ACCESSION   DAFBSV010000050 DAFBSV010000000
VERSION     DAFBSV010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21095
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.051"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..478
                     /locus_tag="LLB18_001701"
     CDS             <1..478
                     /locus_tag="LLB18_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBK5244703.1"
                     /translation="TAVVELTKANRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTV
                     LQSGLTTGADGKLAIDGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIFLTKE
                     NRKVADSSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(902..1072)
                     /locus_tag="LLB18_001702"
     CDS             complement(902..1072)
                     /locus_tag="LLB18_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK5244704.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(1266..1445)
                     /locus_tag="LLB18_001703"
     CDS             complement(1266..1445)
                     /locus_tag="LLB18_001703"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244705.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            complement(1455..1679)
                     /locus_tag="LLB18_001704"
     CDS             complement(1455..1679)
                     /locus_tag="LLB18_001704"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244706.1"
                     /translation="MNGSIKKILRSIDKNLMITEVSYETLQKKKTLIVAAVLFPAPCV
                     CRNCGSAVVDGNRKLMVVKNKKKETIVHFE"
     gene            1832..2944
                     /locus_tag="LLB18_001705"
     CDS             1832..2944
                     /locus_tag="LLB18_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBK5244707.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(3022..3315)
                     /locus_tag="LLB18_001706"
     CDS             complement(3022..3315)
                     /locus_tag="LLB18_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBK5244708.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3483..3797
                     /locus_tag="LLB18_001707"
     CDS             3483..3797
                     /locus_tag="LLB18_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HBK5244709.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            3818..5797
                     /locus_tag="LLB18_001708"
     CDS             3818..5797
                     /locus_tag="LLB18_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBK5244710.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            5810..6136
                     /locus_tag="LLB18_001709"
     CDS             5810..6136
                     /locus_tag="LLB18_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HBK5244711.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            6152..6670
                     /locus_tag="LLB18_001710"
     CDS             6152..6670
                     /locus_tag="LLB18_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244712.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            6670..8022
                     /gene="celB"
                     /locus_tag="LLB18_001711"
     CDS             6670..8022
                     /gene="celB"
                     /locus_tag="LLB18_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBK5244713.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(8106..9611)
                     /locus_tag="LLB18_001712"
     CDS             complement(8106..9611)
                     /locus_tag="LLB18_001712"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HBK5244714.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(9703..10293)
                     /locus_tag="LLB18_001713"
     CDS             complement(9703..10293)
                     /locus_tag="LLB18_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBK5244715.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10472..12118
                     /locus_tag="LLB18_001714"
     CDS             10472..12118
                     /locus_tag="LLB18_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBK5244716.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            12167..12886
                     /locus_tag="LLB18_001715"
     CDS             12167..12886
                     /locus_tag="LLB18_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBK5244717.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13365..14312
                     /locus_tag="LLB18_001716"
     CDS             13365..14312
                     /locus_tag="LLB18_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK5244718.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14324..15244
                     /locus_tag="LLB18_001717"
     CDS             14324..15244
                     /locus_tag="LLB18_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBK5244719.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15285..16742
                     /locus_tag="LLB18_001718"
     CDS             15285..16742
                     /locus_tag="LLB18_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK5244720.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            17087..17701
                     /locus_tag="LLB18_001719"
     CDS             17087..17701
                     /locus_tag="LLB18_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBK5244721.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            17694..19418
                     /locus_tag="LLB18_001720"
     CDS             17694..19418
                     /locus_tag="LLB18_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBK5244722.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19415..20866
                     /locus_tag="LLB18_001721"
     CDS             19415..20866
                     /locus_tag="LLB18_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5244723.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
BASE COUNT         6805 a         3571 c         4233 g         6486 t
ORIGIN      
        1 gacagcggtg gtagaattga cgaaagcaaa ccgacttaca ccaggcggtg tcgtgttgac
       61 aaagatcgat gaccaaagcg gggaagtcct gcaaggagct gtttttgagt tacaagatgc
      121 caatggaacc gttctgcagt caggtctaac cacaggagca gatggaaaac tggcgataga
      181 tggcttagca ccaggagcat atcagctggt agaaactcaa gcgccaacgg ggtatgaatt
      241 ggatgcgaca ccagtaactt tcaagatcga aaaagaacaa gaagtggcga tctttttaac
      301 aaaagagaat agaaaagttg ctgatagctc agatataaga ggaaacaatc caacaagcag
      361 tggaaataag catcttccaa aaactggaga aaccatcatt agccagttta tattgtcaat
      421 attgggtgtg ctacttgttt tcatcagtat aaaatttaga aagaaacgaa atatatgagc
      481 taaaataaaa aattgaataa gcatagtttt taaaatcaac tagtacccat caattgaatg
      541 gaaactaccg attttagaag gggtatacaa acaaatatta gtatcggagt agagaaggtt
      601 gaacccaacc agtaaataag taaagacaat tttgtgctgc gttgagaagt gaaaaataaa
      661 cctttgtagt aatactagtt aataaaaaat atacaaaaac actgcgaaaa tcattcttga
      721 gtttcgcagt gttttttgcc taatgactca agtttattgg gtaatacttt gattttcttt
      781 ctacaaataa tcagcgatca gttgtaattt tttctctagt tttaatggct ctttgtcaat
      841 aaggagaaaa acaagtcggg tcttttgtct cggaaagctt caaccaactc gtgaataaag
      901 gttacgcctc cttgaaaggc gtggaaaaac caagtaatcg atcaatcacc aatttcgcat
      961 ttggtagaac atgtttggtg agctgaaagt aggtggcgtt catgtctgta actaagaatt
     1021 ctatttcttt aggattagtg cagctaagga aatagtttgt taatcgagga attttttgtg
     1081 taggtaaatt ttctcgatta atttttctgt ctcgccatcc gcggaaataa aactcagttt
     1141 atcctcaacg gaaacgtgag aacgaaattc acaaccctca acactcaaga cagaattctt
     1201 ttggaagact ttggtaaata gcttctcaac tctttcaatg tgcgaataac ggttgtcaaa
     1261 gatacctaac aacttttcga aataaaaaat aacgacactt tttcagtcag taaagaagtg
     1321 attttatgtc tgacatgatt tgaaatcgag tgccttggac ggataaaata actttgagcg
     1381 ttccaatggc ttcgacagtt tttacaggta tagcgctgct tttttaggcg tataaccatt
     1441 ggcatatgat tatattattc aaagtggaca atggtttcct tcttcttgtt tttcaccacc
     1501 attaatttcc tatttccatc taccacagca gaaccacaat ttctacagac acatggagca
     1561 gggaagagaa ctgcagcaac gatcaatgtt tttttcttct gtaaggtttc gtaagagacc
     1621 tctgtaatca tcaaattttt gtctattgat ctcagaattt ttttgataga accattcata
     1681 aagcatatcg ttctctcagt tgtttatttt gtggtgattt aatcatacaa gaaaacgata
     1741 tgttttttta taaaaacatg aataggaaaa atagttgaca agaaaatgac aacgccatat
     1801 gatgttccat agtatttaca acctgtcata gatgactgta aaaaataaaa gtaaaaagaa
     1861 aggacgacaa caggtggatt tttatcagtc tctacaacta gatccgttta ttttaaaaca
     1921 aaaaatacga gaagcagctt ctaaaaaaga aaagtgcatg tatatttgtt cattgttttt
     1981 acgatcatta ttcatcgtat tgtttgccat ttgttttatc attataatta caacattatt
     2041 tgaatcgaag cataaaccat acgctgtggt tttattctgt atgttgatga gtattcgttt
     2101 tgttgacttt ggttataaga tttcccattc gatcataggt ttagcaatcg tcatgttctc
     2161 actattagta gcaccgtatg tccagctgat caaatggtca gttatgggca tgttgattca
     2221 ttttatttta ctaagcagca tattaatggc aaccgctagt gatcccaaaa tggggaatgc
     2281 ttctttgtac ggcttttcat atctctttat tgtttattcg ttacctaaag attcgttgaa
     2341 caagaatttc tttacacaaa caagtagctt attatttttg tttttttgtt ggttttcagt
     2401 tctcctttac agaaaacatc gagaaaagaa caaagacaaa agcttgttta aagagatttt
     2461 tttgaaaggc atgtattcgc aggaaaaaat ttggatgctc atctatgcat ttggcattag
     2521 tcttttgatc gttgcaggag agtatgtccc ttttcagcga ttgatgtggg cagggtttgc
     2581 attttcttct attgtatcta gctatggatt gatgtcgatt ggtttcaaag aacgagcagt
     2641 agaccgaatc attggctcat tgattggatg tgttttattt attggtatca gccaatttat
     2701 tccttttaac tgggtcggta tattaggtgg tctagcttta ggtgtttgtt ctacctatag
     2761 atataaaaca gtttttaatt cttttggtgc tttggcaatc actgccagtt tattcggggt
     2821 tccaggagca gtaacgatcc gcatttttga gaatatcctt ggggtatgtt taggaatcat
     2881 gtatattggg gtgactgaaa tacttatccg aaaaataaga gaaaaacacg gtttgaatca
     2941 ttagatgaga tcgaataaaa aataaggaaa aagtgaagat acacatggat gataaattgc
     3001 tatcattcca tgtgtatctt tttacggtaa atcagtgaaa cgttcgactt tcatttttaa
     3061 tttatacttt ttacggagtt cgtttatttg agccatcatt tcggatttgt gatgcttttc
     3121 gattgcttct tcatctttcc aacggtcgat cagtaaaaga gattctggat cttctagtgg
     3181 aaagtaatag tcatatttct cgtttccttc ttctgcacga atcgctttga caatgtttct
     3241 ttcgaccatt tcttctgcaa attttctggc ttgtccattt gtacttgtat acaaaatatt
     3301 cactgtgata ctcactaaat cccctcctga aaaaattcta tcactagtat atcacggtgc
     3361 cagaaattat tattcaagat atgatacaca ttttttccgc aatgctacgg aaatatatat
     3421 tttgaataga aaacgcttac aagatatgct tggtttataa aaataaaagg agtgattgat
     3481 ttatgaaaaa agcattgatt atttgtgcgg caggaatgtc atcctcgatg atggcctcaa
     3541 agacaacgga tttctttaag caaaaaagag aagaggtact cgtagatgca gtttcagcta
     3601 cagaaggcga taatatgatt aagaatagtg attttgattt atttctgatc agcccgcaaa
     3661 cgacgatgtt tttggataaa ttcaaaaaat taggagaatc tgttggaaag cctgttgtta
     3721 gtatcccttt ccaagcgtat gtcccaatcc ctacaggcat ccagaagtta gcagaggtga
     3781 tcgaagagaa catatgatgg aataggagtg gatgataatg aaacagaagg aaaaattgct
     3841 gttgagatat ttgattgatc acaagaagga gtatgtcacc agtcaacgtt tagcttctga
     3901 attgttatta tctgatcgga caatccgtaa ttacttgcag cggatcaaag agttagtaga
     3961 aaaaaacgga ggtaagatca ttgctaaacc aggttatggc taccaactgc atattttaca
     4021 aagactgaca tttgacttgt ttttgagtcg gcaagaaata gtacctggat atgctagaga
     4081 accgcaagga ttttatgagt ccgaagatcg acaaaagtat atattgaacc aattgctttt
     4141 ggaagatgcc attcttttta tggatgattt ggcagaagag ctttatatca gtcgttccag
     4201 tttgacaaag gacatgcaag aaatcaagga gcgattgatt ccatattcac taaaaatcgt
     4261 ttctaagcat ggtcaaggga catggatcga aggggaagaa agaaatcgac ggcattttat
     4321 catggatact ttttttggaa accattatgg aaattcattg aaagaatatt tagggcaaag
     4381 ccgttttttc ccagacatca gttttgaaga gctagtcatt atcattctcg atgaaacaag
     4441 agaagctaag ttaaaagttt cggattttat catacagaat ctgactttac acttggcttt
     4501 ggggatcaaa cggctccgag aagggtttga aatcaaggaa ttaggcatcg aacaagaagt
     4561 ttctaagcga gtagagtatc aagtggcgca gcggatcgtt caacgtattg aggtaatcgc
     4621 aggtgtatcg tttcccgaag aagaaattgc ttatttgaca ttacatctca tggctaagtc
     4681 gaatcacaaa gaaaatcaaa atgatcagga actatcaaag gaattagcga aagttctgaa
     4741 aagattgtct caggaatttc atttttcatt agtagaggat ctccagcttt tcaatggact
     4801 actcgatcat ttgtcaccga tgatgattcg attgagccga ggtattcgca ttgagaaccc
     4861 attgactgag gagataaaga aagaaaatcc caaagtcttt gacgcagtaa aaaggcattt
     4921 cagcaacatg ccggctttga aaaactatac catcaatgaa gatgaatggg cctatttggc
     4981 tttgcatctc atggcggcat tggaaaaaga aagagctgcg cataaactac atgcattgat
     5041 tatctgtgca acgggttacg gcagtgccca actattaaag aatcgcgtag tcagtgaatt
     5101 cggtaaaaat attacagtgg taagtgtaaa aggctattat gagatcaatg aaacaacttt
     5161 aaaaggaatc gacctgatta tttcttctat tgatctttcg acaatgtttt tcaaaattcc
     5221 agttttacat gtcagtattt ttttgaatga agatgatgtt cgtaaaatac gaaaggtagt
     5281 tggagaatct ataccctatc attcctcaga tagaccgata ccagcatttt ctctacagca
     5341 aaaaaagcag atttacaccg aacagttgtc tgaaaaattt ttcaagactt atacgtacga
     5401 accgaaaaag gaagaaattc ttcatgattt gctgcaaaag ctgagcataa atgaagaaga
     5461 aggatatata agagaaatgc gaaagcagat ccagcaacgt gaaaatatgg gacaaatcat
     5521 attcagtgat acagtggcag tcccacatcc cgctgttcca gttggaatcg aaacaaaggt
     5581 agccgttgca ttgattcctt ctgggatgca gtgggatcaa tatcaagaaa ttcattttgt
     5641 ttttttagtt tcgccttctt atgtcgaaaa tgaaggaatt acggtcgtga ctaaagcaat
     5701 cgttaggtta gttgaccagc taaaagtaca gcaggaaatc ttagctgaac ctatttttga
     5761 gaatttcagc agtaaattta tcaaactgat cgaataagga ggaaaacaga tggctgaaaa
     5821 aataaacagt gaaacactac aagtgacttc ttttgatatc attttccata gcggaaatgc
     5881 acggacactg atacatgaag catttcgctc gatgcgtaaa gagatgtttg aagaagtaga
     5941 agagaagttg cgacaagcaa atgaagagat tcttcatgcg catcagtcac aaactcaact
     6001 tctgaaagaa tatgccagcg ggacaaaaat agaaatggaa attatcatgg tccatgcaca
     6061 agatcatctg atgacgacga tgacattatt ggaagttgca caggaaatga attatttgta
     6121 tcaaaaaaat aaatagaaag gaaggatcat tgtgcaggat acagtaaaaa ggaaaatcga
     6181 attagaaaaa aagcaactta gtttgaaaaa catgtatttc aatcgttatc taatcgtacg
     6241 ttacctgact gcctttttct ttttcatgaa catgcaatgg atgattctgc ttctatcagc
     6301 taaaagttta ggaagtagtt taccgatgat tctgatttta gctattttgc ctgcagtagg
     6361 agaacaagta aagctttatc gaaaacacca aacgaacgtt ccatggacaa agtggtattt
     6421 tttgttccag agtgtcttta atttattagt gattccagtg ttgtttacct caggatttac
     6481 attcttgtat ccttttatgg caaataacaa tggaggacag ttatttgttt tcattcttgt
     6541 tgtaagcggt atttttgcca gtgcatttat acagtatcgt ttaaagaaaa tttcactcaa
     6601 ccaagaccaa cagtatatcc gtattaaaca atatgaaaaa gcgttatatt taggaaagga
     6661 gaataactaa tgtttgattt tttgcagaaa tacctgatgg gacctatggg gaaaattgcg
     6721 caacttaaaa tcgttcgggc tgtcatggca gcggggatgg cttctattcc tttcacgatt
     6781 gtaggctcga tgtttttggt tttaaatatt ttgccattac cgttcccatt tttagaagga
     6841 ttttttaatg caactttttt caaagttagt gacttgtaca tgatcgtcaa tacaatgacg
     6901 atggggattt tatctattta ctttgccatt gtgtttgctt atgaattaac gtcaattgaa
     6961 cgagatgaac aaaaattaaa tgttaatccg ctcacggggg cattactatc tgtttttgca
     7021 ttctttatgt gtatccctga attgatcatg actgatggta aaatcagctt gattgcttct
     7081 atcaatgaga cagaaactgt agtaaatggt attaggatgg gctcttttgt cgaacgttta
     7141 ggaacttcag gaatctttac agctattatt atgtcgatta ttgcggtcga attgtattgt
     7201 atgtgtgtca agagaaattg ggtcataaaa atgccagatg ttgttccgcc aggagtttct
     7261 cgttctttca ctgctctgat cccaacattt gtcattgcgt ttgtggtgat gatcatcaat
     7321 ggattattag ttgcactagg aacggatatc ttcaaaatga ttgctatccc atttgggttt
     7381 gttacgcagt tgacgaatac atggcttggt gtcatggtga tttatttctt gatccatgca
     7441 ttgtggatcg tagggatcca tggagcgaat atcatcactt ctttcttgac cccgatcgta
     7501 ttagctaata tggcagctaa cgcacaaggc gcaaattatc cgttggcagg agaattcaac
     7561 aattcttatg taaccgttgg tggatcaggt gcgactttag gattgatcat ctttattgca
     7621 ttcctcgcga aatctgatca gctgaaagtg ttaggaaaag cctcacttgt accaggatta
     7681 ttcaatatca atgaaccaat cattttcggg atgccaatcg tctacaatcc ctatttagcg
     7741 gttccgtttt tcttagctcc gatggcttct gctacactcg cttattttgc cattcggctg
     7801 gaaatcgtca aaccgatgct tgcacagatg ccgtggcctt caccagtcgg gatcggagca
     7861 tttgttggta gtggtggtga ttggaaagct gctgtgttag cagtcatttg tgcaatcatc
     7921 gcattcatta tctggttccc atttatcaaa ttctatgata ataaattatt aaatgaagaa
     7981 agagaaaagg cagcagaatt agctagtgaa aagttaaaat gatttctaag aaaaaaggaa
     8041 ctgtgacaaa aaatcacagt cccttttttt cttagaaatg ggaaaccact agtatataaa
     8101 taccattatt cttcaatcaa ccgcttcacg attgcataat ccccttcata aggttcatct
     8161 acaccattga ttttttgata gggatccacg ccttttcccg caataacgac tgaatcttgc
     8221 ggagcgcttt ctgctaaagc gcgtcgaatc gcttcaggac gatccatttc ataatgaacg
     8281 atcaaatctg gattagtaat tgcttcattg atttcttccg cgattttttt cggatcttca
     8341 aatgctgggt catctgccgt caaaaaggcg atgtcagctg tttctgatag cacttttcca
     8401 aaatcatgtc gacgggagat tgctttgttt cctgggctgc ctaatacaac aattacacgg
     8461 ccatctggat gttcattttt ggcaaatttc agcaatgttt tcaagcttag ataattatgt
     8521 gcatagtcca catagacatg cgctccattg gattggatca attgatccat tcggcctggt
     8581 acacgagctt cttttaatcc gtcttgtgca tcttgactgg aggcacctgt tagtgctgcg
     8641 gcaatgatcg cactggctgc attttcttgg ttgaatcctc cagccagcaa aatatcataa
     8701 gcagtatcgc agatagctaa gcgatcttca tgagaagata aagtaaaacc gtgagtacct
     8761 ttatctgaac ggatcacttg ataattgctt tcttccgaac gaccataagt gatcgttgga
     8821 atctggaata gatcggctgt ttccctaagt aaatcaaaat agtcactttc atgatttaaa
     8881 acaactgttt ttgaattcaa gatcaattgt cgcttgcaat agaaatagtc atcaaatgtc
     8941 ggatgttcga tcggactgat atggtcaggc gagatattca agaagattcc gacatctaaa
     9001 gtcaagccgt atacgcgttg tgttttgtaa gcttgtgaag aaacttccat cactagatga
     9061 gtcataccat tttcaactgc ttctgacatc atacgatata aatctaatga ctcaggcgtt
     9121 gtcaaatggg atttgaaata tgttttgcca tctaacgttg tattcatagt agaaagcaat
     9181 gctgtttttt tatttgttgt gtgatccaag attgcttttg taaagtacgc agcagttgtt
     9241 ttaccttttg ttccagtgaa tccgatcact ttcaatttat tttgcggata gtcgtaaaaa
     9301 gccatagcaa gaagcgccat tgctttacgg atatccgtta cgatgattcc tactgctgaa
     9361 ttttcgtatg gttgttctga tacataatat tgaataccct gttcgattgc tgaatccaaa
     9421 tattcttctt tgaaattcat tcctttacag aaaaacaaag tagaagcatc agcttttctt
     9481 gaatcataac ttaactgaag aaattcagct ttttctggta catcaagatg ccagcctctt
     9541 gttgaaacaa attcttttaa tagattttct tttaatagta aatgacggat gtcttctaaa
     9601 gagaagctca ttgattgatc cctcgcttta ttcaatttct tggtttatta tagcacactc
     9661 tttttaatat atcgtttgtt tccgctatga caaaatccag ctttattcaa attttcttga
     9721 cacaggggac aagcggatga gtattttcat aaacaatgaa ctgactgtaa tagataggag
     9781 aacgaatagt gtctccaaca atccaaaaac ataataattc aaaaagacga taagactatt
     9841 ggtaagtaaa agtccttgcg gcattggaag ccgaaaaaat ttgtggaaaa taatcggcgg
     9901 tatcgttata ccgccatttg aggccccgac tgtgtacaat gtgtaaaccc caagactgaa
     9961 caaaagactt cctgaaatca gtgaaaagaa atgtgaggag atcatttcca cttttggaac
    10021 aatctctaaa acaacaggaa aaagcagact tcccgctaca gtcttaaaaa atactgattt
    10081 tcctaatagg acagcggcta gaagcagcat cataagattg atgctccaaa cagtaactga
    10141 gcgttggata gaaaaggccg tttcaactaa atgtccgatg gcgcccactc cggcggaagc
    10201 tatatcgtga gggagcaaga accaattcaa tccaactgtg ataaagaaaa gacctaaaaa
    10261 tataacgggt agttttttta tttcttgtgt cattgatatc tcctataaat gttagccata
    10321 aaaggctgta tatttcttta ctttaccaaa aaaacgaaac cgaattcaaa aaaacaattg
    10381 ttcttataaa agttatataa aatcgattgc cagtttctgt tttaccaatt aaaatgatag
    10441 taatgttttg tagaaagttg gaatctgacc gatggataat caaagaaaac cagcattaga
    10501 tcaattaaca ccgcaagaaa aaatggcacg aggctctgct tggatgaccg ccagtaatat
    10561 catttcaaga ttgctaggcg ctgtctatat cattccctgg tatgcttgga tgggcgaaaa
    10621 tgctaaggct gccaatggat tattcaatat gggatacaat atatatgcat tgtttctact
    10681 gatctctaca gcaggaatac ctgctgcgat tgcaaaacaa actgcacgct ataattcatt
    10741 gaatgaatat ggcacttcac gacgattatt tatccgtgca ttacagatga tgggcgggtt
    10801 aggcctgttg tttgctttgt tcatgtacat cgcctctcct tggctagctc atgcttctgg
    10861 tggcggagaa gaactgattc caacgatgcg ttctttgagt atcgctgtat tggtttttcc
    10921 ttgtatgagt gtgatacgag ggtatttgca aggcaatcaa gaaatgatgc cttatgcgct
    10981 gtcgcagatt gtagaacagg tggcacgtat tttttatatg ctattggcta cattcatcat
    11041 catgaaagtc atggatggtg actatgtgac ggcggtcacg caatcaactt tcgcggcatt
    11101 tatcggtatg ctagcaagta ttcttgtcct tttgtatttt ttgaagaaac atcaagcgta
    11161 tacatcggcg tttattcact acagcgaaaa caaaataaat attgcaacga aggaattgtt
    11221 gttagatacc gttaaagaag cgattccgtt tattattgtg ggttcagggg taacgatctt
    11281 caaattagtc gatcagttca cttttatgaa gatcatgtct gcatccaccg agtattccaa
    11341 tgcacagtta ctggatcttt tttcgatttt tagtgccaat ccagataagt tgacgatggt
    11401 agttattgca ttggcaacat cgatcgcgtc tactgggtta ccgttgatta cagaagctgt
    11461 tacgttgaaa gatcgagtag gtctggcaaa attgacaagc ggaaatttac agttgttttc
    11521 attttttatg tttccggcga catttggtgt tatgttactt gcctatccgc taaatacatt
    11581 attttataca ccggattctc taggaagtaa tgtactgatc caagcaagtt ttgtaggact
    11641 cttcctagga ctatatatgc tagtttccaa catgctgcaa ggaatgtttg aaaacaaggc
    11701 ggcaattaat tatttggtta ttgggtttct agtgaaactc cttcttcaat acccagccat
    11761 tcgtttattt gaagtatacg gccctttatt ggcgacaatg atcggatttg ctgtgtcttg
    11821 taccttgatc ttaaagagaa tccatgaagt agcccgcttt aaaccaagtt ttgtctggcg
    11881 caggacattg ctgatcttta ttcttacctt gattatgctt ttggcttcgt ggatcacaaa
    11941 gatgattttt ggtgcttttt taaacgaaga tagcaaattc cagtctctat tgttgattct
    12001 tgtagtagca ggtatagggg ctttagtgta tggttattta gctttgaaaa tccgcttggc
    12061 agaaagacta ctaggaccag gaatagcgcg tttacgacat aaattaaaaa taaaataagt
    12121 gaatcagaag agctagattg atgctctttt gaaatggggg aaacgcatgc gtttagataa
    12181 gtttttagca gatatgggac ttggcagccg caaagaagtc aaaggattaa tcaaaaaagg
    12241 aacgatcgaa gtcaatggac aagtggtgaa aagcgataaa gcgcaagtaa atgaattcga
    12301 agatgcggtt acttatttag gagaaatcat tacgtatcaa aaagattttt actacatttt
    12361 gcataaacct gcaggagtca tttctgctac tcaggataat catgatcaaa ccgtaatcga
    12421 tttattggaa gaccaggatt atcgggaaga tctttttcca gtcggccgat tagataaaga
    12481 cacagagggc ctcttgattt taacgaatga cggggtgttt gcccatcagt tactatcacc
    12541 taaaaaacat gtggagaaag aatatctagc tgaggttagc ggtataatga cagaagaaga
    12601 tatccgttta tttgcagaag gactgattat tgatggcgat gagcagacat tgccggcaaa
    12661 actccaaatt gatcaagtag atcaagagac agaaacttca attatccgtc tgattttgca
    12721 tgaaggaaag tttcaccaag ttaagcgaat ggtcaaagca gtaggaaaag aagtcttata
    12781 tttaaaaaga atccgtatgg gaaaattttg gctgcctaaa gatttgaata aagggcaata
    12841 tcgacccatg accaaagaag agctagaaca agtgagagaa aaataattga atggatagct
    12901 aaaagaataa gcagagtagt tgtagcgcca tctgaaaagc agacttgtcc gtctgacttt
    12961 cggatggctt ttttgtgaaa tttcggctta tttccgtaga agctacttct ggaacaccgt
    13021 ttgttcggaa taagggactg tgacaagact tttgttacag tccccattgt tccttgtgac
    13081 tcagagttag atagtaagga cacgatctcc ctaatactca ggccaaaacg ctgaattcac
    13141 aacctctgat aaacggtgtt caatcagctg accctcggta ttagctcaaa aaacggcaaa
    13201 atatgaggaa ctattttccc gtttttttct ctaatactca ggccaaaacg ctgatttcac
    13261 aacctctcct atactttgtt tcattttccc tatactttgt ttatttattc tcattattga
    13321 aagcgctata attacgttgc gaatgaatcg aaaggggttt ttagatgaaa aaacgaaagg
    13381 ggttcaatca tttttttatg aatctatggc gttataaagc acttgtcctg atggctgtac
    13441 cgggtatgct ttggatgatt tttttctttt acatacctgt aatggcgaat gtcgtagcat
    13501 tcaaaaattt tcatatttca gcagatgggt tcttggctag cttgagggaa agtccttggg
    13561 tgggttggga aaatttcaaa tttttatttt cttcggatca agcatttctc atcactaaaa
    13621 atacaatttt atataatgta gcatttatcc ttttgaatct gctgatctca gtcgtatttg
    13681 caatcattat gagcgagttg agaaataaac gactcgttaa agtttatcaa acgatgtcct
    13741 tactacctta ttttctatct tgggtcatta tcagttactt tgtttacgct tttttaagtc
    13801 ctgacaaagg aatattcaat cagtggatca ctggacatgg aggagaagct gtcaattggt
    13861 ataatgaacc gaaatattgg ccgtttatct tggtgttcat tggtacatgg aaagggattg
    13921 gttataacag cattatttac tttgcatctg ttatgggaat cgatccgact tattatgaag
    13981 ctgctatggt tgatggagct agcaaatggc agcagatcaa acatgtgacg ataccacaac
    14041 ttattccact aatgacgatt ttaacgattt tagccgtagg aaacattttc cgagctgatt
    14101 ttggcctgtt ttataacatt cctaggaatt ccggtgcatt atatgatgtg actcaagttt
    14161 tggatacgta tatctacaat ggcctgacat ccacaggaga ttttggtatg acggctgctg
    14221 caggacttta ccaatcagtt gtcggctttg tcttgttgat gatcacaaat acgatcgccc
    14281 gacgttttga tagcgattct gcattattct aaggaggaaa aaaatgaaaa aaaagaaagt
    14341 ggagagagtc caagtccgct ctttcaataa gacggctaat tttttctcta atataatgat
    14401 tgcactcttt gctatttcct gtattttgcc atttatattt gttatcgcca tctcttttac
    14461 cgatgagtcc atattgtcga ctcacgggta cagtttttgg ccagaaaagt tcagtatatt
    14521 tggttatacg tacttgttcg accagatgca ggataaaatt ttccaagcgc ttttcgtcac
    14581 tgtacttgtt actgttttag gtacactgat caatagcacg gctacttctt tatatgctta
    14641 tgcgatttca cggtcaaact ttccattccg tcgttttttt accgtttttt gtttgattac
    14701 gatgttgttc tcaccaggga tggtggccaa ttatcttgtt atgacaaatc ttcttcagtt
    14761 aaaagatacg atttgggcat tgatcttgcc aatggctgtc agtcccttca atattattgt
    14821 gatgcgcaca ttctttaaac gttcggtctc tgattcgatt attgaatcgg cacggatcga
    14881 tggagctagc gaactgcgaa tatttgttca gatcgtttta ccgttagctg ttccaggtat
    14941 tgcgacaatc agtttatttg ccgcattggg ttactggaat gactggttca atgctttact
    15001 atacatccaa gatgataagc tagttccact acagtatctt ttgatgaaaa tccaaagtaa
    15061 tattcaatat ctgacacaaa attcaggagc aggaagccaa ttgacaggcg gattagcctc
    15121 agttccagga gaatctgcca gaatggcgat cgtagtcatc tcgacgttgc ctattgcgat
    15181 cagctatcca tttttccaga agcattttgt caaaggtcta acaatcggcg gagtaaaaga
    15241 ataaagaaac aaaaatataa atcataaaat taggaggaag aaaaatgaag ttatggaaga
    15301 aactagcctt tacaggtgtt tcagcgttgt tgttgggaac attagcagca tgcggaggtt
    15361 ctggttctaa agaccaggca gaagctagca attcggacac tttgcagatg tatcaaatcg
    15421 gagataaacc agataatttc gatcaattga tggaagtagc aaacaaacga atcgaaaaag
    15481 agatcggtgt aaaagtcaat atcaattaca ttggctgggg cgattacgaa aagaaaatga
    15541 acgtcatcat ttcttccggg gaaaattatg atatcgcctt tgcgaacaac tatgtttcca
    15601 atgcccaaaa aggagccttt gctgatttga ctgaattagc gcctaagtac gctgaaaaag
    15661 cttataatga tttagatgaa gcatatatta aaggaaatct ggtcaatgga aaattatatg
    15721 ctttcccagt caatggaaat gtctttgctc aacaagtact tacttttaac aaagctttac
    15781 tagataaata cgatctttca attgatggaa tccaatctta cgctgatgca gaaaaagtct
    15841 tgaaggaatt ccatgaaaaa gaaccaaaca cggcagcttt tgccattgga caaggcttca
    15901 aagtccaagg gaactttgat tatcctttag ggaatacgtt accatttgct attgatctgg
    15961 atggagatga ttcgaaaatc atcaaccaat acgataatga aacgtatatc ggactgttac
    16021 gtacaatgca tagctggtac aaacaaggac tcattccaag tgacgctgca acgagcaata
    16081 aggattatcc actagaagga aatacttggc taatgcgtgg agaaacacaa ggaccgtatg
    16141 attatggcga tacaattttg acaaatgcag caaaacaaga acttgtctca aaagcaatta
    16201 ctgttccact aaaatctaca gctcaagcac aaatggcaaa ttttgtcgta tcaaatactt
    16261 caaaaaataa agaaaaatca gtagaacttc tagggctgct taacagtgat ccagaattat
    16321 tgaatgggct tgtttggggg atcgagggag aagcatggga aaaagtcgat ggttcagatg
    16381 ataaaataaa attgctagat ggttatcagc caaatacaca tatgtctgct tggaatacag
    16441 gaaacaacaa gattctatat acacaagagt ctattacgga tgacatgatt gccaaacgtg
    16501 atcaatcgat tgctgatgca gaaacttcac cgattttagg attcagcttc aacactgaca
    16561 gtgtcaaaac agaattaagt aatatttcta atgtcatgaa tcaatattta gatggattga
    16621 atacagggac tgttgatcca gatgaaacat taccgaaatt gaaagacgct ttggacaagg
    16681 ctggctatga taaggtattg aaagaaatgc aaaaacaata tgatgagttc cgacaagaat
    16741 aataatgaat aaagacaaag gggttgtgac aaaagacgtg tcacaacctc ttgttccgaa
    16801 taaacggtgt tcaaaagcca gtttctcggt attaagctaa atatatgtaa aaatgtggaa
    16861 agccatattc acaaaatttt tcttactact cgaaactaag cggctatttc acaaactctt
    16921 ggtaaacggt gttcaatcag ctaaccctcg gtattcgctc acaaaacgac aaaatatgag
    16981 gaactatttt tccgtttgtt tctctaataa tcaggtcaag gtgctgattg cccaaccttt
    17041 ttttgtataa tgagaaagta taaacttaat gtttggagga gaagatatgt tagggaaggt
    17101 tttggaagag ttatttatcc ggatctgggt cattataaaa ctaaccttgt atttctggat
    17161 atatacattt gccggcggga tcatctttgg attaggtgcg gcatggaaaa cagtcaatga
    17221 actattttat ttgtacggat tcgagtataa agaaatcaca ataaaaagag gctggaatat
    17281 atataaaaga aattttttaa gaggcaatct gctatttagt ttatttttat ctggtactgc
    17341 tttattgagt tacaatttat atttatctgt tcaaatcaaa gggctcattt ttttagctat
    17401 tgattttatt ttactttttg ccttgctctg cctatttgct acttatcaat acagtatgat
    17461 tttagatagt gaatatacga tctctgttcc taatctgcta aagctaagtt ttatttcggt
    17521 tttttccagc ttttcgtctt ttctaaaaat aattattggt agcggtataa ttttaggcgt
    17581 gacttggcaa ttcaaaggat tgatcctgtt tggtgtcatt ggtcttttga cggtttggaa
    17641 tggtacgatg acaacacatt ggcgtgaaga attagataaa cagttggaaa gttatgaata
    17701 agtttcggat tctattttca aaaggaacct tactaaatcg tctgttgcgg aaatacgcgg
    17761 ttatcatgat cggtgtaacg atgactgcta ccgttatttt tagtatccat acttgggaac
    17821 aaaatcaaaa acaggcagaa aacatgacaa gtgatgccgt tcaaagcaca agcagaatgc
    17881 tgaatgataa aacaaccttg agtaggatca tcaaaaacca gcttgtaggg aattccgaaa
    17941 agatcgaaaa tgtgacgacc tacttaacaa aacccataga tcagtatctg atgtatgtat
    18001 acgaacagca aaacagtacc gatgaattag tttctttccc aaatcaaatc aaagatctct
    18061 acgcaaatta tgaagaacta agtgcgatat atatcgtgtt gaatcaacta ccggagtatt
    18121 atgaatcttc tagagaaaac aaaggtgggg aaataaaaaa ggggacacca aaattactag
    18181 acgcctttta tatcaagttg cctatcacac aaggaggagc tgagtcagga agtattttta
    18241 ttggttttca aaagaaagaa ctagatatga ttttagaaaa tctaacgtca ttcaatggac
    18301 tctctttata catgatttct ggaacgacaa atcgactata cacattccat gataataaaa
    18361 tagctaaaga aacgtttgaa agacaagaaa tgatcatcac agagagtctg aagaaaaatt
    18421 cacaattgcc gattgacgat ctggaaaaaa acaattttgt tcaacaccaa gaactgtctg
    18481 atgattatcg tatattagct gtactagata aaaaaagtgt aaaaatcgaa acgggaaaaa
    18541 atcttgcccc gctgatcatt ggtatcatta ttttagacaa tatactgctt atctttcttt
    18601 ataaaacatt caaacgatat tcacagcaag tatctatcgt catgcaggcc atggatcaaa
    18661 cagcagcagg gaatttagag acgcggatcg acataacaaa cacggaatat gaactgaagg
    18721 aactttcaat cggtatcaac gaaatgttgg atagcatcaa tcagtttgta gaagacatct
    18781 acaaattaga aatcaaacag caagacgcac atatgcgggc gcttcaagca cagatcaatc
    18841 cacacttttt atataataca ttagaatata tccgaatgta tgcaatcagc gaaggaagtg
    18901 aagaattagc agatgttgtg tatgcgtttt ccgctttgct tcgaaacaat acgaatcaag
    18961 agaaaacgat cactttaaaa gaagaactgg acttttgcga aaaatatgtc tatttgtatc
    19021 aaatgcgtta tcctaatcga gtagcctatc attttatgat cgatcctgat ttggaaaaga
    19081 tcgaagtacc taaatttgtg atccagccat tagttgaaaa ttattttaaa cacggtattg
    19141 attttactcg attcgataat gcgctaagtg tcaaagtctt gcaggaaggc aaacgggtaa
    19201 ggatcatcat caaagataat ggaaaaggga tgactgaaaa acggctaaaa cagattgaag
    19261 aaaaactgtc tcatcctaaa gtggaacttc acggttctat cggtctgcaa aacgtgaatg
    19321 aacgtttacg tgccagcttc ggcagcagtt attatatgtc gcttgagaat aatgagacag
    19381 gtggactgac cgtttctatt acattcaagg agggatgagc gtgtatcaag tgttattggt
    19441 agatgatgaa tacatgattt tgaatgggtt aaaaaagata attgattggc aaagtttagg
    19501 ctttcaaata gtagcaacag cagagaatgc caaagaagga ctagctgtac ttgaacagcg
    19561 acagattgat ttagtagtaa cggatgtgac aatgccagaa ataaatggac tggaatttat
    19621 tgaagcggct caaaaagaac gtcataattt tgaatttatg attttatcag gataccaaga
    19681 attcgattat ttgaaaggag gtatgcaatt aggcgccgtg aattatttga tgaaacccgt
    19741 gaataagttc gaattggttg aaagcctcaa gaaaatcaaa acacggttag atcagcaaaa
    19801 tgaacaaaaa aatcaacaag aaatctatca agaactgtta ttcagtcaat ggttgaatga
    19861 agaattggat gaaataagtg aagaagaaat aataggacaa ataagtgaga agcagcatag
    19921 gatagtattg attcaactgg caagaactca tgatactctt atcaatagat ggttgcaaga
    19981 acggcaacaa atcttttact atcaacgaaa ttacggagac cgtgtattga tcacgttgtt
    20041 gttggaggca gatgaagttg atggcttctg ttgttttgtt caagaaaact ttcctgatca
    20101 ggaatggctg atcagtatcg gggaagagac agattctttg gacaaaatcc ctgaaacatt
    20161 ccaacaagcg aaagacaatc tacagttgca tcaattttat ggagataaag acgagcatgt
    20221 tttttacgca gtacaagcag aaacaaaaga tcaaaccatc gatttttcaa gtttcagacg
    20281 cgtgctgcaa aataaacaat tggaagtcgc tcaaaaaatg atcactgatt tttttgaaca
    20341 gtttcagtta gcagccatga tgccggaaga tatacgatat tccagttttt tactgtttat
    20401 ggagattcaa cgggaattga ttgatctgga agatgaggaa tatttacaag gaatcgaaaa
    20461 aatccatcag gcaaaaacgg tgcaagaact tcagcagcta cttctgtcat tcatcaaaaa
    20521 gcatcagaga cagaaaaagt acagtgacaa tgtggaaaaa gtaatcgtaa tcctgcacca
    20581 gcattatcaa gaaccactta cactcaaaga agtgtcagaa aacctgcatt taaatgtcat
    20641 gtatctagga cagctgttca aaaaagaaac gaaaaaaagt ttttcagctt atttgaacca
    20701 tttacgtatg gaaaaagcga aacaactgct tttgcacagt aatcaaaaca tcaatgagat
    20761 agcaagtgag attggctaca acaacaccac gtatttctct aaattattca agaaaatcgt
    20821 cggcagatcc cctaaagagt accgagaaaa cagtggagaa tcataaaaga aaaagccaat
    20881 gtaatgaaat aacttataaa aaattgtcta gaaatctaat tttgggctgt tcttattact
    20941 tgaggcaagg cagctttttc atgacctctc gataaacgga gttcaaaagc cagtttctcg
    21001 gtattaagcc aaatttatgc aaaaatgtgg aaagccattt tcacaaaatt tttcttaata
    21061 ctcgaaacta aacagctttt tcacgacctc tccac
//
LOCUS       DAFBSV010000051        20285 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.052, whole genome shotgun sequence.
ACCESSION   DAFBSV010000051 DAFBSV010000000
VERSION     DAFBSV010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20285
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.052"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            140..460
                     /locus_tag="LLB18_001722"
     CDS             140..460
                     /locus_tag="LLB18_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244724.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            912..1112
                     /locus_tag="LLB18_001723"
     CDS             912..1112
                     /locus_tag="LLB18_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBK5244725.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            1259..4048
                     /locus_tag="LLB18_001724"
     CDS             1259..4048
                     /locus_tag="LLB18_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBK5244726.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            4095..4622
                     /locus_tag="LLB18_001725"
     CDS             4095..4622
                     /locus_tag="LLB18_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HBK5244727.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            4643..5833
                     /locus_tag="LLB18_001726"
     CDS             4643..5833
                     /locus_tag="LLB18_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBK5244728.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYSLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            5873..7171
                     /gene="asnS"
                     /locus_tag="LLB18_001727"
     CDS             5873..7171
                     /gene="asnS"
                     /locus_tag="LLB18_001727"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBK5244729.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            8224..8898
                     /locus_tag="LLB18_001728"
     CDS             8224..8898
                     /locus_tag="LLB18_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBK5244730.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            8895..9236
                     /locus_tag="LLB18_001729"
     CDS             8895..9236
                     /locus_tag="LLB18_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244731.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            9266..9625
                     /locus_tag="LLB18_001730"
     CDS             9266..9625
                     /locus_tag="LLB18_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HBK5244732.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            10149..12230
                     /gene="cadA"
                     /locus_tag="LLB18_001731"
     CDS             10149..12230
                     /gene="cadA"
                     /locus_tag="LLB18_001731"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBK5244733.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            12541..14007
                     /locus_tag="LLB18_001732"
     CDS             12541..14007
                     /locus_tag="LLB18_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK5244734.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            14622..15161
                     /locus_tag="LLB18_001733"
     CDS             14622..15161
                     /locus_tag="LLB18_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HBK5244735.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            15235..15675
                     /locus_tag="LLB18_001734"
     CDS             15235..15675
                     /locus_tag="LLB18_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HBK5244736.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            15688..15897
                     /gene="copZ"
                     /locus_tag="LLB18_001735"
     CDS             15688..15897
                     /gene="copZ"
                     /locus_tag="LLB18_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HBK5244737.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            15897..18083
                     /locus_tag="LLB18_001736"
     CDS             15897..18083
                     /locus_tag="LLB18_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBK5244738.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            18103..20274
                     /gene="copB"
                     /locus_tag="LLB18_001737"
     CDS             18103..20274
                     /gene="copB"
                     /locus_tag="LLB18_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HBK5244739.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
BASE COUNT         6777 a         3527 c         4407 g         5574 t
ORIGIN      
        1 aaaaagaggt tgtgacgtgg tcacgacctc tttttgacga ttatgataca aaaaacatca
       61 tttatgaaca aaatgtgaat aacgggcgtt cttgagatat gattttaatt gggaaaaact
      121 tatcgataag gaggtcttta tgaaaaaaag actgttatgg tgtttgctgt ttctatccct
      181 aagtttaaca agtcagccag tttttgctga agaaacacag cggtctccta ttacaggcac
      241 acgtctgtac aaaaatgttt atgtacagac aacagatctt gattctgcga ttcctgaaac
      301 agaagaacgg tctttgcagc caagatttgg ttacttttgg tactgtccga cctgtgatta
      361 tgaaagttgc tggcatttct tacattctac agctgcagct tttgctttta ctcatactca
      421 gaaatatgat ggacatcatc ctgttattta tgaggtatag atatgagcaa aaaagaaaaa
      481 ctaatctcgt tgatcgtatt ggtttgcctt gttcttctgg taactgtcat aggctatcag
      541 aaataccatg agaacatcag acctactaaa gaatcttccc cagcctcgac cgttgaaaca
      601 gaaccgataa gtagtcagaa agaataattt ttttagttta aagaagaaca tcagagcaaa
      661 aaaacaccaa ctgaacaata tgtcgtttat tttaaaaaaa gttcggtttt tcactttatg
      721 taatcgctga gaaaactttt tttaataaaa aaagtcgaaa aactctagct tttttgtaaa
      781 cggtatgata tactatagga gtagtttttg ttcggtaatc tgtggtagct tgtttcaaat
      841 aaacatcttc cagatataca ccattcaagt aattgcaaaa tatgtgttga tacacaagga
      901 ggatttttat tatggaaaca ggtacagtaa aatggtttaa ctcagaaaaa ggatttggat
      961 tcatcactgc agaaaacgga aacgatgtat tcgttcattt ctcagctatc caaggcgacg
     1021 gattcaaaac tttagaagaa ggccaagcag taactttcga tgttgaagaa ggccaacgcg
     1081 gacctcaagc aacaaacgtt actaaagctt aattaaccta tactaaaaaa taaacgccca
     1141 gacatttgcg tgtctgggcg tttttgtcta ttttctttaa aaagcgatga gagtattttt
     1201 ctgcactttg tagtataatt tcaaaagaac attagaggca ggagaagagg aagatatttt
     1261 gaaaccaaga acttatgcag tcgttgatat cgaaacgact gggacgaatc caaaagaaga
     1321 tcggatcatc caatttggct gcgtcatgat tgaatcaggt cggatcactt cacgtttttc
     1381 gatcgatatt catccagggc ggaagatttc aaaacaaatc cagcatttaa cagggatcac
     1441 gaatcaacgc gtccaaaaag cgccttattt cgaagatgtc gcccaaacga tttacaatct
     1501 tttggcagac accatatttg tcgcgcataa tatttatttt gattataatt ttttgaacca
     1561 tgaactcatg cgatgcggac ttcctagttt gaagatacca ggcatcgata cagtagaact
     1621 tgcacaaatt ttcttgccga cggaaccaag ctttcgctta gctgatttgt cagaaagcct
     1681 tggatttatt catgagaatc ctcatcaggc agatagtgat gccgaagtga cgggtcaact
     1741 tcttttgctg atcgaagaac ggatgagaaa attgccaatc atcacgttag agcagattgc
     1801 gcgattaagt agacacacag gtatggatac gagtcgtttc atttatcatg tgattgaaga
     1861 aatgaaagaa aaaccagagc cacttgatcc ctcattagaa atcgtcgatg ggctagcttt
     1921 gcagaaaaaa gaagtggaac tattcacatc cgtccattat ggcgagcgga catatccaag
     1981 aaaaaaacaa gcaaaagaaa aaatgtttgg taaaacactg atgtatcgaa aagaacagaa
     2041 cagactgatg aatgcggtct acgaccattt cacaaaagat gaatcaaaag atttgatgat
     2101 cgaagcagct acaggaatgg gtaaaacaat cggttatctg ctgccattga gttatttggc
     2161 tacacctgaa aaacccgctg tcatcagtac cgtttcgcta gttttgcagc agcagatcat
     2221 agaaaaagac attccattgc tgaatcaatt gctagatcag cccatacaac ctgtaattat
     2281 caaaagctat cgccactata ttgatttaca gcgttttaaa ggcacacttg tggaaccgcc
     2341 agaacaaaaa caatatgctt tgtatcaaat ggcggtctta gtttggctga cgcaaacgaa
     2401 gaccggtgat ttggatgaat tacatttaac aaatttgaac cattcattct ttgcagatat
     2461 cgcgcacaga ggtattggat ttttagcaag aaatcagtca ttttacgaac aagactttgt
     2521 tcgtttcttg caaaagaaaa tcaggcaaag taattttttg attgtcaatc atgcgttttt
     2581 aatacaagaa acacagcgaa aagaaccatt gcttccagct agtccatttt tgttgatcga
     2641 tgaagtacat catttgccgg aaatcgctga aaaagtaaat gacaaacgat taagtattaa
     2701 ctatttccat aaacaaatcc agcaattaga agaaccaaat cagctgtttg accgaataca
     2761 aagctattta ccgaaagaac atgaagcctt acgctggtta tcgatttatc gagaagaact
     2821 ttctgcgcta tgcgaagcac agatttgtat ggcagaagga ttaatgagtt tagtgagcgg
     2881 caagcaacct aacggacagt atccagaaga agtcatgatg acaaaagaga tgttggatca
     2941 gctgccactg gaatctggga cagccattga tcacctgcag cttttttatc aggagatcca
     3001 gcagctacag tcacaaatgc gtctgacttt tgagattatc caagaaagct ggacaaacca
     3061 gatgcggatc gatttagcaa gtttatatag cttatttgat caattagaca agcagtactt
     3121 gctgatggat caatggctgg aagactggcg agatcatttg atccattggt tcgttcctgg
     3181 gaacacagcg cagcagatga tttttcatct ccatgatttt caagcggcta tgttgccgtc
     3241 gactgtttgg tatcctcgat atgatcgtat tctttatatt ggaggaacgc tgaagatcgg
     3301 ccctaatcga cactatctct ctaagcggct tggcattgaa gcagcacctc ttaaagtgat
     3361 tgcctctcct tatgattatg agaaacaggc aaggatctat gtgccaaaag aggcacctgc
     3421 cgtccatcaa gtcagcaatc aagcatatat cgattattta gagacagcac ttacaggtct
     3481 gatcgaacaa gaagatcggc caatacttgt gttattcact tctcatgatg ttttgcagaa
     3541 ggtctatcag aaaatgcatc tgtctatgct agaaaaagga cgagaaatac tagctcaagg
     3601 gtttggcgga agccgggaga agcttttgaa acgcttcatt ttgtcagaaa aaagcgtatt
     3661 gtttggcgct gacagctttt gggaaggtgt agatttgcct ggggatgctt tgcagatcgt
     3721 tgtagtcaca cgtttaccct tcgataatcc gcttcgcccg atggtcaaag ctaggaacgc
     3781 ttatttagaa tcagagggga tcaatccttt ttaccaggaa tccgtaccta aagcagcttt
     3841 gaagttacgc caagcattag gtcgcttgat aaggacggag acagatcgtg gcgtattgct
     3901 tattttggat cgaagactag tcactgcaaa atatggtgca cggatcatcc atgcattacc
     3961 gaaaaaagta ccgatcaaag agctagctat ggaggaaatc tatcaggaca tccatgaatt
     4021 cttaaagaaa aatgaagaag gaagttagag gagctgtctt ttttcataat taaaatctgc
     4081 tataatgaaa aggaatgaag ataaaggagc gacgaccctt gaagaaaaaa cagacaaagg
     4141 aaaaaacgat taatcgcgtg ttacttggct tgatcgtatt tttattagcg gtcatcgtga
     4201 tcagctcgat tttttacttg cgttccagtc gtccggcggt gcaggcgaag aaagaagcag
     4261 tagaaatcgc aaagaaatat gcaaatcttg aggaagccga tcatttttat tggtttactc
     4321 gaaagaagac atacttttca ctgacaggta caaatgataa aggaaaagaa atcgccgtta
     4381 tcattcctaa atctggtgaa aaagtaaaag tattggatca aacaaaggga ctgactgaaa
     4441 acgaagcaaa acagacaatt gctgcggccc atcctgaaat ccaaatcgaa aaagctgctt
     4501 tagggatgta tgatgatcag cctgtgtggg aagtagtagg aaaagaaaca aatgggaaac
     4561 tgaattatta cctgattggc tttgaatctg gagatgaagt caagacaatc aagggaattt
     4621 aaaaggtaaa ggaatgaatg ggatggagtt atcaaaaaga acaaaacgat tagaaccgtc
     4681 tgtcactttg gcagctgcgg caaaggccaa ggcattaaaa gcaaaaggca gagatgtgct
     4741 gagtttgact gtgggagaac cggattttgc gacaccagaa aacatccaag aagcagcaat
     4801 cgaagcaatc cgcaacggga aagctagcta ttatacacca acagcaggaa tcccagagct
     4861 tcgacaggca atcgttgatt atctgaagaa aaactatgga cttgtctatg aaccttcaca
     4921 aacagtcgta acagacggag cgaaatttgc tttgtatacc cttttccaaa cgatccttga
     4981 cccgcaagat gaagtcatca ttcctgtgcc ttactgggtc agttacggtg agcaagtaaa
     5041 actggcagaa ggacttcctg tctttgtgaa aggggaagaa tccaatagct ggaaagttac
     5101 tgttgaacag ctagaacaag cacgttcaga aaaaacaaaa gccgtaatca tcaattctcc
     5161 atcgaatccg actggaatga tttatagcaa gaatgaactg caggcaatcg gtgaatgggc
     5221 agtaaaaaat gatattttga tagttgctga tgatatttat ggtcgtttag tttataatgg
     5281 caatgagttt actccaattg caacgatttc agaagcaatc aaaaatcaga ctatcatcat
     5341 caacggcgtg tctaaaacat atgcgatgac aggctggcgc attggttatg cggtgggaaa
     5401 tcctgtgatc atcaatggaa tgatcgctgt tgcttcccag tcaaccagta atccgacagc
     5461 agtcagtcaa tatgcagctg ttgaagcatt gaaaggcgag caagatacag tggaagaaat
     5521 gcggaacgcc tttgaagaac gcctgaatac gttatattcg cttgtggcag aactgccggg
     5581 tgtttctctt gaaaagccac aaggagcttt ttatcttttt cctaatgtaa aagaaacgct
     5641 acgcatgtgt aaatatgaaa atgtcacaca atgggtagaa gatcttttag aagaaacagg
     5701 ggtagcgctt gtgactggcg aaggctttgg ggcaccagaa aatgtccgca tgagttatgc
     5761 tactgatcgc gctacgttag aagaagcggt acgcagaatc aagcaattta ttgagagtaa
     5821 aagtcaaaat taatcctaaa gaaattcaag gaatataaaa ggagagtcat acgtggaaca
     5881 aattcaaatc atcgattcga aaaaccatgt gggagaaaca gtaacaatcg gcgcttgggt
     5941 cgcaaataag cgatcaagcg gaaaaatcgc atttttacaa ttaagagacg gaacagcctt
     6001 tttccaaggt gtagttgtaa aaagcgaagt gtcggaagaa gttttccaaa cagctaaaaa
     6061 tctacaccaa gaaacatccg tgttagtaac tggagaaatc cgtgaagaca gtcgttcaaa
     6121 atttggttat gaaatcggaa ttacaaatgt ggaagtggta agcgagagcc acgattatcc
     6181 gatcacacca aaagaacacg gaacagactt cttgatggat catcgtcatt tatggctgcg
     6241 ttcttcaaga caacatgcga ttatgcagat cagaaatgaa atcattcgtg caacgtatga
     6301 attctttaat caacatcatt ttgtcaaaat tgatccgccg atcttgactg gttctgcacc
     6361 agaaggcact acggatctat tcgaaacaaa ttactttgat caaaaagctt atttatctca
     6421 aagtggccaa ttatacatgg aagctgctgc tatggctttc ggaaaagtct tttcattcgg
     6481 tccgactttc cgtgctgaaa aatcaaaaac acgacgtcat ttgatcgaat tctggatgat
     6541 cgaaccagaa atggctttca ctcatcaaga agaaagttta gaagtacagg aacaatatgt
     6601 agcattctta gtacaaaatg ttttagatca ttgcgaatat gcattagatg tactaggacg
     6661 agacaaagaa gtcttaaaaa cttatacaaa attgccattc cctcgtatta cttatgatga
     6721 tgcgatcgaa ttactgaaga aaaatggatt tgatgacatc gaatggggcg aagactttgg
     6781 ttcacctcat gaaacgttca ttgcgaattc attcgaacag cctgtcttta tcctaaacta
     6841 tccaaaagcc atcaagccat tctacatgaa accacatcca acaagagaag acgtggtgat
     6901 ctgtgcagat atgatcgcac cagaaggtta cggtgaaatt attggcggaa gcgaacgggc
     6961 aacagactat gatttcttgc tagaacaaat ccgtaatcac ggtttggatg aaaaagaata
     7021 ttcatggtat cttgatctac gtaaatacgg ttctgttccg cactctggtt ttggtctagg
     7081 tcttgaacga acagtcactt ggattgctgg tatcgaccat gtacgtgaag ctattccatt
     7141 cccacgtttg ttgaaccgaa tttatccata agaggtgatg aaaaagctgt tctgcatcaa
     7201 gtaattagaa cagccaagca aaaacagctg ttcatgtttt tgaattggcg ggacttatta
     7261 ccgcagatgt aagcttttga ataccgttta gtggagaggt tgtgaaaaag ctgtttagtt
     7321 tcgagtatta agaaaaattt tgtggaaatg gctttccaca tttttgcata aatttggctt
     7381 aataccgaga aactggcttt tgaacaccgt ttaaggaaga ggttgtgcgc ctgccgttca
     7441 gctccgagtc acaaggagta atttcaaaaa acagtttttc atgtttgatg actattgtga
     7501 cttgtgaccg aggagttggc cggagagcac cgtttattct aaaaaagaac tgcgaactct
     7561 cgcagttctt tttttaaaat acgggataaa ggaagtttcc agcagacaag agaagaaagc
     7621 aaaagaaatt gctatttgat tcacaaggtt ctataacgaa atcgcaatca atcaaacatt
     7681 tacaaagaag gtaattcaaa tggaaatctg atttgatgat gcttctgctg ttgaaataaa
     7741 gcagcatcta gcacctgaaa acaaactaat agtaacattc gaagatggag taggtccgta
     7801 ttttcagcat gcaataatcc atatgtaagt tcaattcacc cttgaaatca tcggaccaga
     7861 taaagttatg accaatctat cccaagcaat ctagaagaga tattagtaaa gggacattta
     7921 ctagaagtct tagatgagcc tataaatata tgttctgatg gcgtcatcag tggtctgatt
     7981 gacggaagct taggtgtgat cgatctctct ggaccaaaca acgaaggaat caaggggaat
     8041 ccggcacgtt aagaaaaaaa tagcataaaa aactagacac ttgatgagcg ttcattcaat
     8101 tgtttgaagg gactaggctg gtgtcatttt ttatacatat attttctctt tcgtcttgat
     8161 agggcttatg ggataatata aggaagaaaa tcatcgtttt attcaaaaag gagtttttga
     8221 caaatgaaaa aacgtatatt atttatcggt gatagcatta cagacgcagg aagagaccga
     8281 gcagaagcaa ctgatctagg taaaggttat ccacttttga ttgccggaaa actaatctcc
     8341 caatatccaa cgatggaatt tgaatgcatg aaccgtggga taggaggaga caaaattgca
     8401 gatctgcaag tacgctggca agaagattgt ttagctttac aacctgacta tgtatcgatt
     8461 ttgatcggaa tcaatgatac ctggcataat actagcgatc aggctatatt cggaactgag
     8521 aaatctgctc agcaatttga atccgtttat cgaaaattac taaatgaact tcaaacagtg
     8581 ggaatctgca acatcatctt gatggagccg tttgtacttc ctataaccga cgaccgtcat
     8641 ggctggcgta aagacttaga ccctaaaatc caaattgttc gtaaacttgc taaggaatat
     8701 ggcgcattgc tggttccttt agatggtata ttcaatgctt tagggattgt ttatggtttt
     8761 tcgaaatata caagagaaga tggggtccac ccaacgattg gcggacatga gatcattgca
     8821 caaagctgga tagatgcaat tgccgcagtc gattttttta gtggagataa aaatgagcga
     8881 aagaaaagtg agaaatgatg gaaatacggt gggcagtaaa agaagatcta cctcaaatca
     8941 atcagctgat tactgatcat ccagaatcat tcgtaaaagc aaaaacggca gctgacctaa
     9001 atgataagaa taaactattg ctcgttgctg taacaaaaga aaaacggatt atcggatttg
     9061 cgcaagcgga cgtgcaacag tcagaagaac gattggatca gcgaccatca ggaaaactaa
     9121 tccaacacac attagtaaca aaagaaaata cggaagaaat ccaaaaaaaa tttgcagaat
     9181 atttgatact ggaagctaaa aaaagaagaa taaaatcatt ttttgcccag ttttaatcaa
     9241 aaacagtaat agaaggagaa atacaatgag ttgtttagga aatgtcatct ggtttatatt
     9301 cggcggacta atcggtggtc ttagctggtt agcagcgggg atactttggt gtatcacgat
     9361 cataggtatc ccaatcggta tgcaatgttt taagatcgcc tccctttctt ttgcgccttt
     9421 tggcaaagaa gtaatttatc accagtctgg catgtcattg attgttaata tcatctggct
     9481 gatcgtttca ggcctaccaa ttgctctcgc acatgtcgtc agcggcatcc ttctatgtat
     9541 cacgatcata gggatacctt ttgccaagca atctttcaaa cttgctcgat tggcgttgat
     9601 gccattcggt gcagaaattg tataaaagag aataataaag gttagataaa gcatagagtc
     9661 aggtgggata catgtatttc acctgactct atgcgttctc ctgtataagt tcttccatgt
     9721 gacttttacg tcttttattt atatggggtt actgtttatg gaaagttgaa ataattttca
     9781 ttaaagaact ctttctatat ttttgaaagc gtagtggagc ttcgaatatc tgggaaggac
     9841 attttgcagg gattgaaaaa agatattgtc ctatcgaaaa attaatgaat ttagacaaat
     9901 tgccagcaac aggcttcaaa cttagttgct atcctgtcaa gatcaagaag gcaagtgcgg
     9961 gttggataag agcagtggca atgatcgaaa agaaaaagaa agaataagcc aaaacatctg
    10021 tatggaagaa attttccgat gcagatgttt ttcatttttt ctttcggata ccttgacata
    10081 tgaataaccg ttcatttata attagttatg aagagatatt catatgttga ggcgaggagg
    10141 tcattaaaat gaaaagttac agattagaag gtttagattg tgcgaactgt gcaatgaaaa
    10201 tcgaaaaagg agttcagaag atcaatggag tcaaggaagc aacggtaaac ttcacttctg
    10261 gaaaactaac gattgacgca gaggaagatc atttggctac gattgaacaa gaaataaaaa
    10321 aagtagtgaa ggaattagaa ccagatgtca aagtaacaga aatagataag gaaaaagtat
    10381 ctgaacatgg aaatgaaaaa gagagaaata cgctgttccg gattttattt tcccttgcag
    10441 gtatcgcttt attgctatta tttgatttta atgaaccaat tcgcttgata gggtatttat
    10501 tgatttatct gctgatagga tatgatgtag tgaagaaggc agtgatgaat atcgtcaaag
    10561 gaaaaatctt tgatgagaat tttcttatgt ctgttgctac gattggcgct atgttgatcg
    10621 gtgaatatcc agaagccgta gcagtgatgc tattttatca aatcggcgag tatttccaag
    10681 gattggcagt cagtcattca agaaaatcga ttcgcgaatt gatggcgatc cgtccagaaa
    10741 cagctcacgt gcagacgacg gaaggattga tgaccgtgaa ccctgaagac gtgcagatcg
    10801 gtcagtttgt acttgtgaag cctggtgaac gtgtaccgtt agatggaacg atcatcgaag
    10861 gagaatcatt agtcgatacg tcagcactta caggagaatc agtccctaaa tctgtatatg
    10921 ttggtgaaac agtattaagt ggatttatca ataaaaataa accattttta gttcaagtag
    10981 aaaaatctta tgaaaattct actatcagca aattattaga attagtagaa aatgccagca
    11041 gtaaaaaagc accagctgaa aatttcatta ctaaattcgc gcgctattac acaccagtcg
    11101 ttgtaggatt ggccgtttta ttagctgttt tacctccact tgttgtttct ggagcggcgt
    11161 tttctgaatg gatctatcga gcattgacat ttttagtgat ctcatgtcca tgtgcattag
    11221 tgatctccgt accccttagt ttctttggcg gtatcggagg agcaagtaaa atcggtgtat
    11281 tagtaaaagg ttcaaattac ttggagttgc ttgcacaaac tgagacagtg gtattcgata
    11341 aaaccggcac attaacgaaa ggtgactttt cgatccagac gatcgataca aaaatcgatc
    11401 caaagatatt catgcaatat gttgcgagtg cagaacagtt ttctacacat ccgattgctc
    11461 aatctgtttt agaaggctac gcaggtccgc ttttaccaac agctaatatc caagaatttg
    11521 caggtgaagg gatcttagct gaagttgatg gcaaacaagt attagcaggt aatcacaaat
    11581 tgatggaaag atttgaaatc tcttttcctt caagtcaaga aatcggtaca ttgctttatc
    11641 tagcgatcga tcaaagttac agtggttatc ttgttattgc agataccttg aaagaagatg
    11701 ccgtagacgc attggttcaa ttaaaaaagg ctggtgtgaa gaacacagtc atgttgacgg
    11761 gcgattcgaa aaaaattgct gatcatatcg ggaagcaagt aggcgtggac aagatatata
    11821 gcgaattgct tccagaagat aaagtgcagc ggttagagga aatcttacaa agaaacaata
    11881 aaaagaccgc atttgtcgga gatggaatca acgatgcacc ggtgctagca agagcagatg
    11941 taggaatcgc aatgggtgga ttgggaagcg atgctgcaat tgaagcagca gatgtagtca
    12001 tcatgaatga tcaaccatcg aagattgcag aagcaatcca tttagcaaag aaaacattga
    12061 aaatcgtcaa acagaacatt gtctttgcta ttgggataaa aattttggta cttgccttag
    12121 gtgcttttgg ttttgcatca atgggagatg cagtatttgc agatgttggg gtgacagtat
    12181 tagctgtttt gaatgccatg cgaagcttgc atgtaaaaaa taaacgttga tcaatgaaga
    12241 ggacgaatga acgtcctctt ttttttatat ccttttctta atgaaaaatg taaagaaaat
    12301 agataggatt ataaaataac taatgttttt aattttgcag aaaattcaaa atagcttgaa
    12361 attcaataag gtaaatgaaa taaaagaaaa taacttattt ttttgatgga aaaaatatga
    12421 aaaaacgatg tgtattaaat aaaagaatac acacataaaa taacactgtc ttgtaagttt
    12481 gttaaaaatt gaatatgatt acatctggat aacaaatttt tatcataaag gagagaacga
    12541 atgaacaaca aacaattacg ctggtttact gttgcgttaa ttgcatttaa catggtttgg
    12601 ggcatgggga atgtagttaa taactatgct cagcaaggag tatcagttgt cacctcttgg
    12661 ctattgattt tggccattta ttttattcca tacgcattga tcgttggaca attagggtca
    12721 gccttcaagg atagtaaagg aggcgtcagt tcatgggtcg aaaatacgac atctaataaa
    12781 cgactggcat actatgccgc ttggacttac tgggtcgtcc atattcctta tttggcacaa
    12841 aagcctcaag caatcctgat tgctggcggt tgggcagtcc aaggaaatgg aaatatcgta
    12901 aatacgatgt cagtacaaat ggtagcagtt atttcactta ttatatttct tgccttttta
    12961 tatttatcaa caaaaggact ttctactttg aaagtgattg gcggactggc cggaacagcg
    13021 atgttcgtca tgtcgatctt atttattctt ttagctgtaa cggcaccgtt catcaatcca
    13081 acgatggaat ttgccacacc acatatgaat caagtgaaaa catatattcc aacatttgat
    13141 ttcagttatt tcacaaccgt ttcgatgcta gtatttgcag ttggaggagc ggaaaaaata
    13201 tccccttatg tcaactctac aagaaatcct gcaaaggaat ttcctaaagg gatgatcttc
    13261 ttagcagcaa tggtagggat ttgtgctgta ttaggctcag tcgcaatggg tatgctgttt
    13321 gctagcgata atattcctaa agacttgatg gcaaatgggg catacagtgc ttttcaaatt
    13381 ttaggtaatt actatggtat cggtaactca ttgatgatca tttacgcatt gacaaacatg
    13441 attggacaaa tctccgcatt agccttttca attgatgcac cactaaaaat cttgttagca
    13501 gatgcggatc cagaatttgt accaaactgg ctacgtaaac gtaatcgtaa aggtacattg
    13561 gtgaatggtt atcttctgac aggtatacta gtaggaatca ttattttgtt gccgatcttt
    13621 ggtatcaaag atatgaatga attagtaaaa tggttgacga acttgaactc agttgtcatg
    13681 ccaatgcgtt acctatgggt gttcttggca tatatgatgt tgaataaagc ttataagaaa
    13741 ttcaattctg aatataaatt tgttaaaaat ccaaaaatcg gttttatctt tggtgcttgg
    13801 tgctttgcct tcactgcgtt tgcatgtatc ctaggaatgg tgccaaaagt agattatact
    13861 gctgatccta aagcatggtg gttccaatta ttcacgaata tcatcacacc aattgtcttg
    13921 atcttattag gtatgatctt gccagcaatt gctcgtcgag acaaaaacaa agaaatcact
    13981 gaaccagaaa cagtggttca gccttaaaat agaaatactt gttacaagag gttgtgacag
    14041 aagtggtcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttctca aatttttgtg
    14101 aagtttcggc ttgtttttcg cagaagctac ttctggaaca ccgtgaatca gaggttgtga
    14161 aaaagctgtc ctgcatcaag taataagaac agccaaacaa aaatagcccc tcatattttt
    14221 cgttttgctg ggcttattac cgcagatgca agcttttgaa caccgtttaa gaaagaggta
    14281 gtgagcctgc cgtttaactc cgagtcacaa ggagcaattt caaaaaacaa cttctcatgt
    14341 ttgttgacta ttgtgccttg tgaccgaggt gttggcagga gaacaccgtt taaggaagag
    14401 gttgtaaaat cagcgatttg acctgagtat tagaggaaca aacgaaaaaa tagctcctca
    14461 tattttgccg ttttttgagt taatgctgaa ggtcagctga ttgaacacca tttattcgaa
    14521 acaagggact ttgacacgac ttttgtcaca gtcccttgtt tttttgcggc gttataagtg
    14581 gtatgatcga accaaattcc aaagagaagt gagggagaag aatgaagatc atcgtgattg
    14641 gacaaagtgg gtcgggaaaa tcgaccctcg caaggaagat caaagaaatc accgactttc
    14701 cgctactgcc gctagacctt ttatggcata caacagacta cagtattcag gcaaaaaagt
    14761 ggtttttgca agaacagcaa tcgtttatgg tatctaatcc gtcatggatt gttgaaggaa
    14821 attatacttc tacattagag gaaaggatta aagaagcaga taagatcatt tggcttaaag
    14881 tgccgcgtta tctcgccatc taccgagtag tttggcgttc tctaaaaaga aagataaaca
    14941 aaaaatctcg gccagatatg cctgaatcat tttcagagaa actaaacagg gaatacttag
    15001 aatttttatc ttttatctgg cattttgaag aaaacaatga accgaaaata cagcagctga
    15061 tccaagtagc taatgcaaga aataaactga tcatccttaa aacaagacga gagaaacaag
    15121 aatttttaac taaattgaaa atagagagca aaaataattg acagtttttg tttacaagcg
    15181 taatctgtat tcataagcta atgattacat ttgtaaacga aaggtgtgaa ataaatggaa
    15241 aaagtcaaaa cgccagtaaa gatcagtgat tcagagtggg agatcatgcg tgttatttgg
    15301 acacttggac agacgacagc ccaagaaatc acgcagatct tagctgattc gatggattgg
    15361 aaaccagcaa cgatcaaaac tttgctggga cgtttggtaa aaaaagaagt gatctggaca
    15421 gaacaagaag gaaaaaaatt catttatcat ccagctgtct cggagatgga aacagttcgc
    15481 agtgcgacgg aaaatctttt ttcccatatc tgtgcaaaaa ggattggaga gacgattgcg
    15541 gatctagtag aagaagccac tttgactcaa gaagatatca atgagatttt gaaacaactg
    15601 gaacaaaagc aaccagtaga tacgatcgaa tgtaactgta tcccaggtca atgtgaatgt
    15661 aaacaacatc aataggagga agaaaaaatg aaacaacaat tttcaatcga aggtatgagc
    15721 tgcaatcatt gtgcagcaag agtagaagaa acagtaagcg cacttgacgg cgtgcaaaaa
    15781 gtgaaagtaa atttgaaaaa agcaaacggt acggtcaagt ttgatgaaac aaaagttcaa
    15841 tccgaaaaga tttgtcaagc aatcaatgga ttgggttata aagcagaggt gatttgatgg
    15901 caacagcaga aaccaaaatg gatacgttcg tcattacagg tatgacttgt gcaaattgtt
    15961 ctgctaggat cgaaaaagag ctgaacggac aacctggtgt ggtcaatgcc acagtcaact
    16021 tggccactga aaaagcaagt gtcaaatatg aagggacgac cactgaaaaa ttaatccaaa
    16081 gcgtagaaaa catcggttat ggtgcaattt tgtacgatga agcccacaaa caaaaaattg
    16141 cagaagaaaa gcaagcgtat ttgaaaaaaa tgctattcga tcttatattg agtacggttt
    16201 tgactttgcc gttgatgttg tcaatgattg ctatgatgtt aggaagccat gcggcgattg
    16261 ttcacttttt tcattttcca atcgtccagt tagtgctgtc tgctcctgtc caattttatg
    16321 tcggtgctcg tttttataaa ggtgcgtacc atgcaatcaa gacgaaagca ccaaatatgg
    16381 atgtattggt agcaattgga acatcggctg cctttgcatt gagcatttac aacggatttt
    16441 tccgtggaca cccccaagat ctttattttg aaagcagcag tatgatcatc acgctgattt
    16501 tgctcggcaa atatttggaa catacagcaa aaacgaaaac aggtaatgca atcaaacaat
    16561 tgatgtctct tcaaacaaaa accgcccaag tgataagaaa cgggaaagaa gaaacgttag
    16621 cgattgaaga agtagtcgtt ggtgatcaac tagtcatccg tcctggtgag cagattccag
    16681 cagatggtcg aattatttca ggaagcagtg cgatagatga aagtatgctt actggtgaaa
    16741 atcttcctgt agaaaagaat ccggatgaca cgctttttgg cgggacaatc aatacgaatg
    16801 gtctgctaca catggaagtc acacaagtcg gcaagcagac agtattagcg caaatcattc
    16861 aaatggtgga agatgctcaa gggagcaaag ccccaatcca aaaaatcgca gatcggatct
    16921 cagggatttt tgttccgatc gtattagtca tcgcgtttat cacgctcata gctacaggtt
    16981 tgatcactgg tgattggcaa ctcgcattga tccatagtgt ctctgtatta gtcattgcgt
    17041 gtccatgtgc attaggttta gcgaccccaa cagctattat ggtaggaacg ggtgttggtg
    17101 cacgaaatgg aattttaatt aaaggcggag aagcattaga agcagctgct cacttagaca
    17161 gcattgtttt ggataaaact ggaacgatta cagaaggaaa gcccaaagtt acagatctag
    17221 tcggttcaaa agaagtccta tctatttttt atactttaga acaagcttct gaacatccac
    17281 taggtaaagc aatcgtggaa tacggaaaac tgcaagaagc agcaacatac gatatgattg
    17341 attttacagc ccacccaggt gctgggatca gcggtacgat taatggagta cgctattttg
    17401 cgggtacacg taaacgatta attgaattga acctatcatt tgatgaatac caagaacacg
    17461 cgttagaatt agaacagcag ggaaaaacag tcatgttttt agctgatgaa aagcaagtga
    17521 tcgggtggat tgccgtggct gatcaaatca aactagaagc caaacaagca atcaagcagc
    17581 tccagaataa aggattagat gtttttatgc tgacaggaga caacaaactg gcagccgaaa
    17641 cgattggtaa acaagttggt attgatccaa agcatatctt tgctgaagta cttccagagg
    17701 ataaagcagc ctacgtagaa aaacttcaga aagatggcaa aaaagtcggt atggcaggcg
    17761 atggaatcaa tgatgcaccg gccttagcat tagctgatgt cggtatggca atgggaagtg
    17821 gaacggacat tgcgatggaa acagccgatg tgacgctgat gaatagcagt ttggcatcca
    17881 ttgcacaaac aatcgagttg tctaggttga cattgagaaa aatcaaacaa aatcttttct
    17941 gggcttttgt ctataatacg attggtattc cttttgccgc actaggcttt ttgaatccaa
    18001 tcattgcagg aggagcgatg gcgtttagtt ccgtcagtgt attgttgaac tccctgagct
    18061 taaatcgaca catgaaaaag taagagaagg gatggagtaa aaatgaatgg gaacgatatg
    18121 gagaaaaaac atgagcataa aaaagaagta gtaaacaaag aaagtacaga atctcatgaa
    18181 aaacagatgg agatgaaaca tgaccatagt cagatggatc attccatgca catgggacat
    18241 aaccatggag atatagcaaa cagcaaacaa atggaccatt cgatgcacat ggatcacgaa
    18301 cacggcggca tggatcattc catgcacatg gggaatttca aacaaaaatt ttggctatcg
    18361 cttatcctag ctatcccaat cattcttttt tcaccaatga tgggaatgga atttccattt
    18421 caagtaacgt ttcctggttc tgattggctc gtattgatct tagcaactat actatttatc
    18481 tatggcggtc agccattttt aagtggagct aagatggaat tgaaacaaaa aagtcctgct
    18541 atgatgacac tgatcgcgat ggggattaca gttgcatata tttatagtgt ctattcgttt
    18601 atcgcaaatc tgctcaatcc acatacacac gtcatggatt tcttctggga attggctact
    18661 ttgatcgtta ttatgctact aggtcactgg attgaaatga atgctgtgtc gaatgccagc
    18721 aatgctttac aaaaactagc agaattactg ccagaatcag tgaaacgctt gacgaaagat
    18781 ggaaaagaag agacagtttc attgaaagaa gtaaacgaag gtgatcgttt gatcgtccgg
    18841 tctggtgata aaatgccaac agatggtgta atcttgaaag gtgaaacaat tgttgacgaa
    18901 tcagctgtga ctggcgaatc aagaggaatc aaaaaacaag ccaatgacaa agtgattggc
    18961 ggttctatca atggggatgg aacgatcgaa atcgaagtaa ctggaactgg tgaaaatggt
    19021 tatctagcga aggttatgga aatggtgcga aaagcacaag gagaaaaatc caagctagag
    19081 tcattatctg acaaagtggc aaaatggctg ttttatgtcg cattaattgt gggtatcctg
    19141 gcattcatcg cctggttgtt cttgacagat cttcctaatg cattagaacg tatggtaaca
    19201 gtctttatca tcgcctgtcc tcatgctcta ggtttagcta tcccattagt tgttgctcgc
    19261 tccacatcaa tagcagctaa aaacggatta cttttgaaaa accgcaatgc actggagcaa
    19321 gccaatgatc tagatgtgat catgctggac aaaacaggaa cactaacaga aggaaaattt
    19381 actgtaacgg gtgtcgaagt acttgatgat gcgttcaata aaaatgaaat ccttcaatat
    19441 ctaggagcct tggaagcgaa tgccaatcat ccattggctg ttggcattat gaattatttg
    19501 aaagaacatg aaatcaagcc ttatcaagct gaaaatctaa aaaatctttc aggagtcggg
    19561 ctagaggcaa cagtcaaaaa acaacaagtg aaaatagtta atgaaaaaga agttgagcgt
    19621 ctcggattaa acgtagaaca agcattattg aaaccttacc aagaacaagg aaataccatc
    19681 agcttcctga ttttagaaaa tcatctagct gcaatcgttg ctttaggtga cgtagtaaaa
    19741 acagaagcaa aagaatttat ccgaacattg aaagaaagaa aaatcactcc tgtcatgctt
    19801 actggtgaca ataaaaacgc tgcccaagca gtagcagatt atttagggat cgaagaatat
    19861 tatggcggtt tattaccaga tgataaagaa gctgttgtcc agaaatacct tgaccaaggg
    19921 aaaaaagtaa tcatggtggg tgatgggatc aatgatgcgc caagtttagc ccgtgcttca
    19981 atcgggatgg caatcggtgc agggacagat atcgcaatcg attctgcgga tgtcgtattg
    20041 acaaacagcg atccaaaaga tattttgcat tttcttgatc tagccaagca aacgcgaaag
    20101 aaaatgatcc agaacctctg gtggggggca ggttacaata ttcttgcaat tccgctagca
    20161 gccggaattc ttgcgccaat tggtatcata ttaagtccag cagttggtgc tgtcttgatg
    20221 tcgttaagta cggtagttgt agctctaaat gctttgacat tgaaaatcaa ataataatga
    20281 aaaaa
//
LOCUS       DAFBSV010000052        19996 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.053, whole genome shotgun sequence.
ACCESSION   DAFBSV010000052 DAFBSV010000000
VERSION     DAFBSV010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19996
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.053"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            4..816
                     /locus_tag="LLB18_001738"
     CDS             4..816
                     /locus_tag="LLB18_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBK5244740.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            813..1613
                     /locus_tag="LLB18_001739"
     CDS             813..1613
                     /locus_tag="LLB18_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBK5244741.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1774..3042
                     /gene="rseP"
                     /locus_tag="LLB18_001740"
     CDS             1774..3042
                     /gene="rseP"
                     /locus_tag="LLB18_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBK5244742.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3110..4819
                     /locus_tag="LLB18_001741"
     CDS             3110..4819
                     /locus_tag="LLB18_001741"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBK5244743.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            5031..9383
                     /locus_tag="LLB18_001742"
     CDS             5031..9383
                     /locus_tag="LLB18_001742"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBK5244744.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFQSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            9527..10000
                     /gene="rimP"
                     /locus_tag="LLB18_001743"
     CDS             9527..10000
                     /gene="rimP"
                     /locus_tag="LLB18_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBK5244745.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10024..11199
                     /gene="nusA"
                     /locus_tag="LLB18_001744"
     CDS             10024..11199
                     /gene="nusA"
                     /locus_tag="LLB18_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBK5244746.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNSKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11221..11514
                     /locus_tag="LLB18_001745"
     CDS             11221..11514
                     /locus_tag="LLB18_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBK5244747.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11511..11822
                     /locus_tag="LLB18_001746"
     CDS             11511..11822
                     /locus_tag="LLB18_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HBK5244748.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11835..14141
                     /gene="infB"
                     /locus_tag="LLB18_001747"
     CDS             11835..14141
                     /gene="infB"
                     /locus_tag="LLB18_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBK5244749.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14168..14515
                     /gene="rbfA"
                     /locus_tag="LLB18_001748"
     CDS             14168..14515
                     /gene="rbfA"
                     /locus_tag="LLB18_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBK5244750.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(14623..14844)
                     /locus_tag="LLB18_001749"
     CDS             complement(14623..14844)
                     /locus_tag="LLB18_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK5244751.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYYRKKKVEFFTFLFLFFG"
     gene            15292..17655
                     /locus_tag="LLB18_001750"
     CDS             15292..17655
                     /locus_tag="LLB18_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
                     /protein_id="HBK5244752.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKLGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRNDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFHSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAATLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
     gene            18023..18946
                     /gene="truB"
                     /locus_tag="LLB18_001751"
     CDS             18023..18946
                     /gene="truB"
                     /locus_tag="LLB18_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBK5244753.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            18950..19891
                     /gene="ribF"
                     /locus_tag="LLB18_001752"
     CDS             18950..19891
                     /gene="ribF"
                     /locus_tag="LLB18_001752"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HBK5244754.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKKDEQATAEYFSQQ"
BASE COUNT         6863 a         3512 c         4389 g         5232 t
ORIGIN      
        1 agaatgttac gtttttttcc gcaaaaaaac aaatatattc aagaaaaaag cgaatttcaa
       61 tttaataccg atggaccaat tcctcagcac attgccatca tcatggacgg caatggtcgt
      121 tgggcgcaaa accgtcgttt gccacgagtt gctggccata aagaaggcat ggaaacagta
      181 aagaaagtca caaaaaaagc atcaaggctt ggagtgaaag tgttgacgct ttatgccttt
      241 tcgactgaaa actggaagcg accaaaagat gaagtaagtt ttctcatgca actacctgtc
      301 gacttctttg atacgttcgt accagaattg attaaagaaa atgtcaaagt tcatgtcatg
      361 ggttatgaaa acgtattgcc agaacatacg caagatgctg taagacgtgc aattgagcaa
      421 acaaaaaaca atactggaat ggtattgaat tttgctttga attatggaag tagagcagag
      481 atcgtgactg ctgtccaaga aattgccgaa gaagtagcaa aaggagaaat acacgcagaa
      541 gaaatcgatg atgaattgat tgctaagcat ttaatgacag gtttcttgcc taaagagtta
      601 caagatcctg agctgatgat ccgtacaagt ggagaagagc gaattagtaa ttttctgtta
      661 tggcagatcg catatagtga gctgtatttt acaaaagcgc tttggcctga ttttgatggt
      721 gcgcatcttg aagaagcaat cgcctcttat caaaatcgag accgtcgatt cggcggtgta
      781 aaaaaaacag aagatgagaa aggggatcag tcatgaaaca acgtgtgatc acagcagctg
      841 tggcgctagt cttgtttatt ccgattatat ggatcggagg catagcggtt gagcttacag
      901 cagcaatctt agcggtagta ggagtttacg agctgttccg gatgaaagga ttgacactct
      961 taagttttga aggagtttta tccgccgttg gtgcagtgtt acttgttttg ccaaaagaaa
     1021 gatggttttt ctttcttcca gagaatgtaa gtacatttat gttattttat cttatagtta
     1081 tgattctttt aggaacatca gttatttcta aaaatacgta tacgattgat gaagcaggtt
     1141 ttcctgtgct tgtcagcttg tatgtgggaa taggtttcca gaattttgtc aatgcacgaa
     1201 cagaaagctt ggctgttttg atatttggtc tatttattgt ttgggcaact gatatcggag
     1261 catatatggt tggtcgacgt tatggtcagc ataagttaag tcctgatatt tcgcccaaca
     1321 aaacgattga aggtgcgctc ggtggtatcg gtagtgctgt tgtagtcgca tttctttatt
     1381 tattgctata cccagcaaaa gaactattca atcatggtat gtttgtcatg cttctgatga
     1441 cgattatttt ttcagcagtc ggacaatttg gtgatttggt cgaatctgca atcaaacgtc
     1501 attatgatgt gaaagactcg ggaaatatct taccaggcca tggtggaatc ttagaccgtt
     1561 tcgacagttt gctgtttgta tttcctatca tgcatttatt tggcattatt tagtaagtat
     1621 acctgcgttt ctttgtgaat ttcataaaag acgcaggttt ttatttttca ttatattgat
     1681 actattggtg tctttggtat actatggtaa aattatagtg ttttatcgtt gttttataaa
     1741 aaacacaaaa aacaagtaaa ggagaaaaaa gctatgaaaa cgattctgac atttatcatc
     1801 gtttttggta tattagtgat tgttcatgag tttggtcatt tcttctttgc gaaacgatca
     1861 ggaatcctcg tccgcgaatt tgctatcggt atgggtccga aaatttatgg gcatcaagca
     1921 aaagacggga caacatatac gcttcgccta ttacctattg gcggttatgt tcgaatggca
     1981 ggcaatgggg atgatgaaac agaaatggca ccaggaatgc ctctttctct tttactaaat
     2041 tctgacggca tcgtagagaa gataaattta agtaagaaaa tccaattgac aaatgctatc
     2101 ccgatggaat tgagccgtta tgatttagaa gatgagctga ctatcactgg ttatgtgaat
     2161 ggagacgaaa cagaagtagt aacctaccct gttgatcacg atgcgacgat tattgaaaac
     2221 gacggaacag aaatcagaat tgcgccaaaa gacgtacagt tccaatcggc taaattgtgg
     2281 cagcgtatgc tgaccaactt tgctggaccc atgaataact ttattttggc aatcgtgtta
     2341 ttcatcattc tggcatttat gcaaggtggt gttcaagtga cgaacactaa tcgcgtagga
     2401 gagatcatgc ctaatggagc tgcggcagaa gcaggcttaa aagaaaatga tgaggtagtc
     2461 agtgtggacg gaaaagaaat ccattcatgg aatgatctga caacagtcat tacgaaaaat
     2521 ccaggtaaaa cattagactt taagatcgaa cgagaaggtc aggtgcaatc tgtcgacgtg
     2581 acaccgaaat ctgtagagtc aaatggcgaa aaagttggcc aacttggtat aaaagcccca
     2641 atgaatacag gttttatgga taagatcatt ggagggacgc gtcaagcttt cagcggttca
     2701 ttggaaattt tcaaagcctt aggatcacta tttacaggtt tcagtttaga taaattaggc
     2761 ggacctgtca tgatgtacca attgtcttca gaagcagcaa atcaaggtgt aacaactgtt
     2821 attagtttga tggcgcttct ttcaatgaat ctcggaatcg tcaatctgct tccgattcct
     2881 gccttagatg gcgggaaatt agtcttgaat atttttgaag ggattcgcgg gaaaccatta
     2941 agtcaagaaa aagaaggaat attgacatta gctggctttg gatttttaat gttgttgatg
     3001 gtgctagtta catggaacga tattcaacga ttctttttct agaaaaagtt gacaaatagg
     3061 gtataataac aaacgataac tattttgagg aaataaagga gtatatagaa tgagacaatc
     3121 aaaaatgttg attccaacat tacgcgaagt tccaaatgat gcagaagtat taagccatca
     3181 aatcttgcta agagctggat atatccgcca agtatcagcg ggtatttatt catatctgcc
     3241 attagcaaat cgtgtattgg aaaaactgaa acgcattatg cgggaagaat ttgaaaaaat
     3301 cggagcggta gaaatgctga tgcctgccat cttgccagca gaactttggg aagaatccgg
     3361 gcgttacgaa acatatggac caaacttgta tcgtttcaaa gaccgcaatg atcgaaaaat
     3421 gatccttgga ccaactcacg aagaaacttt tactgatttg atgcgtaatg aaatcaattc
     3481 atataagaaa ttacctttaa atctttatca aatccaacct aaatatcgtg acgaaaaacg
     3541 acctcgcttc ggtttgcttc gcggaagaga gtttatcatg aaagatgcat attctttcca
     3601 tgcaacggaa gaaagtttgg acgagacata taaagattac gaaaaagcct ataccgaagt
     3661 attcaagcgt tgtggcttag aatttcgctc gatcatcgga gacggcggcg caatgggcgg
     3721 gaaagactca aaggaattca tggcgatctc agaaatcggg gaggatacga tctgttattc
     3781 gactgaaagt gattatgctg caaacttgga gatggctaca agctactatg tatcaaaaaa
     3841 atcgcatgaa acacagcttg aattggagaa agtagctaca cctaacgtaa aatcaattga
     3901 cgaagtagca gatttctttt ctgttgaacc tcaaaaaatc atcaagtctg tattgttcat
     3961 tgcggatgaa caacctgtcc ttgttttggt acgtggagac catgaagtca atgacgtaaa
     4021 actgaaaaac tttttatctg ctgacttttt agaagaagca acagaagaag aagcacaaaa
     4081 atatctaggt gctgagtttg gttctgtcgg accagtcggt gtttcagatg acgtaaaagt
     4141 atatgcagac cgttatgtcc aagatttagc gaatgccatt actggagcga acgaaacagg
     4201 attccactat aaaaatgtga atccagaacg cgatttcact gtgctttctt atgaagatct
     4261 tcgttttgta caagaaggag atccttcacc agacaacaac ggtgttcttg cctttactcg
     4321 aggaatcgaa atcggacata tattcaaaat cggcactcgt tacagtgaat ctatgggagc
     4381 aactgtacta gacgaaaatg gacgagaaaa atttgtgatt atgggctgtt atggtatcgg
     4441 tgtaagtcgt ttattatcag caatcgtaga acaacattca gatgaacaag gaatcaattg
     4501 gccaaaagga attgcgccat ttgatctgca tatcgtccaa atgaatctaa aagacgaata
     4561 ccaaacaagc ctgacgaatg aactagaaga agcgatgaca aaagctggct atgaagtact
     4621 ggttgatgac agaaatgaac gcgcaggagt gaaattcgcg gattctgatt tgattggctg
     4681 tccaatcaga atcactgtcg gtaaaaaagc agtggatgga atcgtagaag tgaaaatcaa
     4741 gaaaactggc gaaatggttg aagtacgtaa agaagaattg gcgaatactt taccaatcct
     4801 cttgaaccaa ggcgaataat aagcgttaaa acacagaaaa taaaaatagc tgaatcagct
     4861 gtttttgaca atctgatgat tcgcttttaa aattggaact gcgatttgaa tcgcagttcc
     4921 aattttttaa tgtaaaactc agaaaaaacg agtatactaa aaggtactga aaaagaagag
     4981 gataagatgc gatcaattgc attgtttctc atcagaaagg gcgtatatct ttgtcagaaa
     5041 aacgagattt atttgaaaaa ctgttggaac aaatccaact agaggaagca gaaaaaaatc
     5101 atccactgct tactgctggt gaaatggata gtgtagtggt ccatcgtaaa tcgcgtttat
     5161 gggaatttac gctacatttt tccaaaattt tgcctattat gctatatcgg tcattgactc
     5221 agcatctgac tatcgctttt aaagatattg cacaagtcaa actgaatatc ttagcagatg
     5281 accagacatt cgatgaacag ctcttgcaag attactgggc ccaagctttg gaaaatcagc
     5341 aatgcgatac accactagca cagcaagtat tgaaaacgca ggtacctgtg ataaaagatc
     5401 gtaaagtcat cttgccaatc gacagtacag gagctatttc ttatttgaag caacaatact
     5461 tgccattagt agaagagttg ttcgtcagtt acggattccc aaaatttcgt atcgaaccag
     5521 aagtggatga gcagcaagcg gaacgtgtat tgaaactttt tgaagaacgc aaacaagaac
     5581 aggcagaagc ctttatgaag caagcagctg aaagtctagt tgtccacgaa caaaagaaaa
     5641 aggaaagaaa agagcaatcg ccagctcttg aaggacccat ccagctagga cgaaatattc
     5701 cagccgatga accaacgaca ccaatgatca gtatcgttga agaagaacga agagtcacac
     5761 ttgaggggta cgtattcgac aaagaagtca gagaactacg ttcaaaacgc aagatcttga
     5821 ctttgaaaat cacagattat acttcatcat ttatcgtcaa aaaattctcg aacggcgaaa
     5881 aagatgaaca agtatttgat gcgatcagtg tcggtagctg gttaaaggta cgaggaagta
     5941 ttcaagaaga tacgtttgtc cgtgatttgg tcatgaatgc gcaagatatc atagaagtca
     6001 aacatacacc tcgcaaagat tatgctcctg aaggggaaaa acgagtagag cttcatgttc
     6061 atagcaatat gagtacgatg gatgcaacaa acagcatctc tgatcttgtg gcacaagcag
     6121 gaaaatgggg acaccgagct atcgccatta cagaccatgg tggtgcgcaa gcctttccgg
     6181 aagcacatag tgctggaaaa aaagcaggtg tgaaaatctt atacggcgtg gaagcgaatg
     6241 tcgtagatga tggtgtccca attgcttata atgatgcaca tgaagcattg agtgaagcca
     6301 catacgtcgt atttgacgtg gaaacgacag gattgtctgc agtatatgac acgatcatcg
     6361 agctagccgc agtcaaaatg tataaaggaa atgtgatcga aagctttgat gaatttatcg
     6421 atccaggaca tccattgtca cgaacaacgg tagatctgac tggtatcacg gatgaaatgg
     6481 ttcgagggtc aaagtcggaa gaagaagtat tgcggatgtt ccttgaattt tcaaaagata
     6541 caattttggt agcccacaac gcggcttttg atatggggtt cttgaatact agctacgcaa
     6601 ggtatggtat tcctgaagcg gccaatccag tcattgatac gttggaatta gctagatatc
     6661 tgtatcctca attcaaacgt ttcggattag gtgtgttatc taaaaagttt ggtgttagct
     6721 tggaacagca tcaccgagca atctatgatg ctgaagcaac tggtcactta gcatggatct
     6781 ttgtgaaaga ggcaatggac aatcataaca tgctttatca tgatcagcta aatgagcata
     6841 tcggagaagg agattcttac aaaagggctc gacctttcca tgtaacgatt ttagcaaaaa
     6901 atcaggcagg actgaaagat ttgttcaaac tgatttcaat gtcgaatgtc gaatacttcg
     6961 aacgcgtccc acgaatacca cgctcccaat tgaaaaagat gcgtgaaaat ctattgatcg
     7021 gctcagcttg tgataaggga gaaatattcg aagccatgat gcaaaaaggg gtagaagagg
     7081 caagaaaccg agcaaaattc tatgattata ttgaagttat gccaaaagcg gtctatgcgc
     7141 ctttgatcga gcaagaattg gtaaaaaatg aacatgattt ggaagaaatt atccaaaatt
     7201 tggtagaaat cggaaaaagt ttggataaaa tcgttgttgc aacaggtaat gtacattatc
     7261 tgaacgaaga agatgccatt taccgaaaaa ttttgatcaa ttctatgggc ggagcgaatc
     7321 cgttgaatcg tcatagtttg ccggatgtcc atttccgaac aaccgatgag atgctaactg
     7381 catttcactt tttaggggaa gaaacagcga aagagatcgt agtagaaaat acgaataaaa
     7441 tcgcagatat ctgcgaagaa gtgattccag tcaaagatga actttataca ccgaagattc
     7501 caggttcaga agatgaaata tcagaattga gttacacaaa agcaaaacaa atgtacggag
     7561 atccgttacc tgagatcatt caaaaacgat tagaaaaaga gttgaattct attaatggta
     7621 atggcttctc ggttatttat ctgatcgccc aaaaactagt gcataaaagt aatgaagatg
     7681 gctatctagt aggttcacgt ggctctgttg gctctagctt tgttgcgacg atgacaggaa
     7741 tcactgaagt taatccatta gcccctcatt attattgtcc agagtgccaa tattccgagt
     7801 tttttgaaga tggtacgtat ggttctggat ttgacatgcc agaaaaacaa tgtccaaaat
     7861 gtggtgcacg cttaaacaaa gacggtcatg atattccatt tgagacattt ttaggattcc
     7921 atggagacaa agtgcccgat attgatttga acttctcagg tgattatcaa gcagaagccc
     7981 ataactatac gaaagtattg tttggcgaag actatgttta ccgtgccgga acgattggta
     8041 cagtcgccga caaaacagca tatggctatg taaaaggata cgaaagggac aataatctgc
     8101 agtttcgaag tgcagaagtc gacagattag caaaaggcgc tactggagtc aaacggacaa
     8161 ccggccagca tccagggggg atcatcgtta ttcccgatta tatggatgtc tatgatttta
     8221 cgccgatcca atatccagca gacgatcaaa attcagaatg gaaaacgact cattttgatt
     8281 tccaatcgat tcacgataat gtattgaaat tagatattct agggcatgat gacccaactg
     8341 ttattcggat gcttcaagat ttatcaggga tcgacccaca aacgatccct acggatgacc
     8401 cggaagtgat gcggatattt gccggtcctg aagtacttgg agtaagtcag gaacaaattt
     8461 attccaaaac agggacatta ggtattccag aattcggcac tcgttttgtt cgagggatgt
     8521 tagaagaaac gcatcctaca acttttgcag aactactgca aatttccgga ctatctcatg
     8581 gtacagacgt atggttagga aatgcggaag aattgattcg acgaggagat gcgacactgg
     8641 cggaagtaat cggctgtcgt gatgatatta tggtttattt gatccatgct ggattagata
     8701 gcgggatggc atttaaaatc atggaaactg ttcgtaaagg acaatggaac aagatccctg
     8761 atgaattgcg agaaacctat ctatcggcga tgaaagaaaa taatgtgccc gactggtata
     8821 tcgattcttg ttcaaaaatc aaatatatgt ttccgaaagc ccatgctgca gcttacgtat
     8881 tgatggctct tcgtgtcgct tatttcaagg tttatttccc tattttgtat tactgtgcat
     8941 acttttctgt acgtgcagac gactttgatc tagtctccat gtgcaaagga aaagatgctg
     9001 tgaaacaagc aatgaaagaa atcacggaca agggattaga tgcttccgta aaagaaaaga
     9061 atcaactgac agtgctggag ttagccaatg aaatgctgga acgaggattc aaatttggaa
     9121 tgattgattt gtataaatcg gatgccgtta actttgttat tgaaggtgat acgttgatcg
     9181 caccatttag agctgtccca agtttgggaa ccaacgtggc gaaacaaatc gttgaagcaa
     9241 gaaaagacgg tccattttta tccaaagaag atcttgccac ccgcggtaaa gtttcaaaaa
     9301 cattgatcga atatatgaac gacaatggcg tattgaaaga tctaccagat gaaaatcaat
     9361 tatcgttatt cgatatgcta taagcatctg ttttcctgtc tgcttgtaat tttaagcaga
     9421 gtatggtata gttcttatag gtaatgatac taactgtgag tgagcggatt tttcgctcac
     9481 tctttttaat ggaattacgc acttaatttt taaggaggcg aaacttttga gtagcgtcgt
     9541 tgaaacagtc acagaaatgg tgacaccgat tttagatgaa caaaattttg aacttgtcga
     9601 agtcgaattt gtaaaagaag gaaaaagctg gttcttacga gtatttattg acaaagaagg
     9661 cggtatcgat atcgaagaat gcgcctttgt cagtgagaaa ctgagtgaaa aacttgatgc
     9721 agcagatcca gatccgattc ctcaagctta tttcctggag gtatcctccc cgggagcaga
     9781 gcggccattg aaaaaagaaa gcgactatga aaaggcactt ggtgattatg tccatgtctc
     9841 cttataccaa ccagtagatg gcgaaaaaca atatgaagga tttcttcaat catttgatgc
     9901 tgaacagctt acattgaaaa tacgcataaa aacacgagaa aaagaattga cttttgaccg
     9961 aaaaaatatt gcaaaagctc gcttagctat ccaattttaa tcacggagag gaatcagaaa
    10021 aaaatgagta aagaaatgtt aaatgcgtta gacgctttag aagctgaaaa agggatctca
    10081 aaagaaatcg tgatcgatgc attagaagca gcattggttt ctgcatacaa acgtcactat
    10141 ggccaagcac aaaacgtcga agtggaattt gatcagaaaa aaggaaagat ccatgtctat
    10201 gcggtaaaag aagtaacgga agaagtgatg gattcacagt tggaagtctc attgaaagat
    10261 gcacttttaa tcaatccagc atatgagatc ggtgatacga tccgttttga agtaacacca
    10321 aaagattttg gacggatcgc tgcgcaaacg gctaaacaag ttattttaca gcgtgtacgt
    10381 gaagcagaaa gaacgattat ttataacgaa ttcagtgctt atgaaaaaga catcatgcaa
    10441 ggaatcgtcg aacgccagga taaacgttat atttatgtca atcttggtaa aattgaggca
    10501 gttctttcta aacaagatca aatgccaaat gaattttatc aaccacatga tcgaatcaaa
    10561 gtttatgttt cccgagtaga aaatacgtct aaaggtccgc aagtatttgt tagccgcagc
    10621 catccagacc tattgcgtcg cttatttgaa caagaagtac cagaagtcta tgatggaatc
    10681 gttgaaattg tcagcatcgc ccgtgaagct ggcgatcgtt caaaagtggc agttcgctca
    10741 aatgatccaa atatcgatgc agtcggtaca tgtgtcgggc caaagggaca acgagttcaa
    10801 gcaatcgtca atgaattaaa aggcgaaaac atggatatcg tcgaatggaa tgaagatcca
    10861 gctgtattca tcgcaaatgc attgaatcct gcacaagtca tggatgtgat cttcgatgag
    10921 acaaattcaa aggcctgcac agttgtcgtt ccagactacc aattatcgct agcaatcggt
    10981 aaacgcggac aaaatgcacg tttagctgct aaattgacta accataaaat cgatatcaaa
    11041 tcagaatctg acatgacgga attttatgaa aatcaagaac aacaaaaaga aacagaagaa
    11101 ctgcatgatg aagcaatcgt tcagtcagat ttaacagacg atgaatatga aacaattgca
    11161 ttcaacaatg aaacggtcga agaaaaacca gaagcttaac tttagtaagg aggcaaagag
    11221 atgaaacaaa ggaaaattcc tttacgcaaa tccgtggttt caggtgaaat gaaacctaaa
    11281 aaagagatgg tccgaatcac ccgttcaaaa gaaggggaag tatcgatcga tccaactgga
    11341 aaaatgcctg gacgaggagc gtatgtctca cttgagccgg aagaagtaca acaagcttgg
    11401 gataaaaaaa ttctcgatcg agtactcgaa acaacattaa cagatgagtt ttatcaagaa
    11461 cttcttgact atgtcactca ccaaaaagca cgtaaagagt tatttggaaa atgaatacag
    11521 ttaatcggca aaaagccatg aatctcatcg gtctagcgat gcgcgcggga aaactaatca
    11581 cgggtgaaga actgaccatt gctgaaatcc gcaaacaaaa agcaaaattg gtgtttgtgg
    11641 caaccgatgc aagtgagaat acaagaaaaa agataaaaga taagagttca tattatgaag
    11701 ttccttgctt tgagctattt tctgaagcag aaatcacgca gatgatcgga aaacctcgca
    11761 aggtattcgg aataatggat gccggatttg cgaagaagac caaggagcta attgaaggtt
    11821 aggaaggtga ttgcatgggc aacaaaagaa tctatgaatt agcaaaagaa ctcaaaaaat
    11881 ctagtaaaga cgtcgtggaa aaagcacaac aacttggcat cgatgtgaaa aaccatatgg
    11941 gtgcgattac tagcagtgat gagaagaaat tgcaacaagc gttcaaaaac ccaagcacga
    12001 aacaacaagc tgcacaacaa gcaagcagaa aaccagccaa tcaacagccg aacgatcaac
    12061 gtaaaaaaga aacaacgaac aatcaacaaa aaaataaaaa taaccgcagt tatcaagatc
    12121 gcggtcaagg gagcggtcaa gtgaatcaag gaaaaaaacc aacaacaaac caaaataata
    12181 cgggaaatac cagcagccaa aatcgtcaag gaacgagcca aggcggcaat caaaaccgta
    12241 ctaacaataa caacaaacca aacaataaca atcgcggcaa atttaataat aataaccgta
    12301 atcgttataa taaaaaaggt aaaaaaggca aacagcaaca atcaactaaa ccagctgtac
    12361 caccacgcaa attccgtgaa ttgccagatg tattagagta tactgaaggt atgaacgtag
    12421 cagatattgc gaaaaaaatt catcgtgagc cagcagaaat cattaaaaaa ttatttatgc
    12481 ttggtgtcat ggtcaatcaa aaccaagcac tggataaaga tacgattgaa ctgttagcga
    12541 cggactatgg catggaacca caagaaaaag tccaagttga cattgctgat atcgataaat
    12601 tcttcgaggc agaagaagtc gatccagata aattagtctc acgtccgcca gtagtaacga
    12661 ttatgggaca cgtagaccac gggaaaacaa ccttattgga tacattgcgc cattcacgtg
    12721 taacaagcgg cgaagccggc ggaatcacac agcatatcgg tgcctaccag atcgatattg
    12781 atggtaaacc aatcactttc ttggatacac caggacatgc ggcctttaca agtatgcgtg
    12841 cacgtggagc aagtatcaca gatatcacga tcttagttgt tgctgcagat gatggcgtca
    12901 tgccacaaac agttgaagca atcaaccatg ccaaagctgc aggcgttcca atcatcgtcg
    12961 ctgtaaataa aattgataaa ccaggtgcaa atcctcagca tgttatgcaa gaattaagtg
    13021 agtatgaatt aattcctgaa gcatggggtg gagaaacgat ttttgttgag atctcagcga
    13081 aattcggcca aaacatcgaa gaattgctgg aaatgatcct gttagtcgca gaagtagaag
    13141 atttaaaagc agatccaaca caacgcgcaa tcggaacagt gatcgaagca cgtcttgata
    13201 aaggtaaagg tcctgtgtca accttacttg tccaagaagg aacacttcac gttggtgacc
    13261 caatcgttgt cggtaatact tacggacgtg tccgtgtaat gacaaacgat cttggccgtc
    13321 gcgataaaga agcaggacct gcaacgccag tagaaatcac tggcttgaat gatgtacctc
    13381 aagcaggtga ccgtttcgta gtcttcgaag acgaaaagac agcacgtgca gcgggtgaag
    13441 aacgcgcaaa acgtgcatta ttggaaaacc gtgctgccac aagccgtgtg actttggaca
    13501 acttatttga aagcctgaaa gaaggcgaat tgaaagaagt taacgtaatc atcaaagcag
    13561 atgtacaagg ttcagcagaa gcactggctg catcattgaa gaagattgat gtggaaggtg
    13621 tccgtgtaaa aatcgtccat tcagctgtcg gagcaatcaa tgaaagtgat gtaaccttag
    13681 cagcagccag caacgctatt atcatcggtt tcaacgttcg tcctacaccg caggcaaaag
    13741 tgcaagctga tactgaagaa gtcgatattc gtcttcaccg tatcatctat aaagccatcg
    13801 aagaaatcga aactgcgatg aaagggatgc tagaccctga atttgaagaa aaaatcaccg
    13861 gtcaaatgat cgttcgtgaa accttcaaag tttctaaagt tggtacgatt gcaggtgcct
    13921 atgtaacaga aggatatatt cgtagagata gcggtgtccg tgtaatccgt gacggaatcg
    13981 taatctatga aggccaactt gcaagtctga aacgattcaa agatgacgtg aaagaagtca
    14041 aaatgggtta tgaatgtggt gcgatgattg aaaaattcaa tgacatcaaa gtagatgacg
    14101 taattgaagg atttatcatg gaagaagtca aaaatgacta aaaactgata aaaggaggcc
    14161 aatcattatg gctaactacc gtgatcgccg agtcggtcaa gaaatcttaa aagaagtcaa
    14221 tgatattttg cgcaaaaagg tccgtgaccc tcgtgtggag aacgtaacga tcacagatgt
    14281 gaaagttacg ggggacttac agcaagcaac gatctattac agcattttat ctgacttagc
    14341 atcagataag aaaaaagcac aagatggatt gaataaagca tcaggattga ttcgtcgaga
    14401 gttagggcac aatctaagta tttataagac acctgaattg ttctttgaac ttgatgaatc
    14461 agttgtctat gggaaccata tcgatgaatt gcttcgcgac ttgaacaaag actaatcaaa
    14521 aaatcccgca aatcctgtga aatcaggggt tgcgggattt ttttgttttc attaagacgt
    14581 attacctaag agttccatga ctttagtctg gtagcgtgtc agctaaccaa aaaagagaaa
    14641 aagaaaagta aaaaattcga ctttcttttt tctatagtat ataaattttt gcatatagat
    14701 aaagatcaag ataccgataa cggaagctag attgtaatct attttagtga cagtcaggta
    14761 tagccaagta actagaagat cagtggaacc tgcaccataa aagtttgagt ttgtcggtcc
    14821 gttgacagtt aaaagaaaaa tcacgttgaa gttattgata tttccgatta cgccgcttcg
    14881 atttggtcac gatccaaatt ttggataatc cctgtagaaa ttagcatagt agctgggata
    14941 ccaattcaca tattgacaaa gataacagag acttttacat aaaacggatc aatcaggaaa
    15001 ggaattgctc gatccagccc cagttttcca acaatgtgtt aactggccta gcgtcattca
    15061 gcaaattatg catgatgagg agcgaaatga actgcggaac agccattgtg ataacgacaa
    15121 gttttttgga tcaatgtaaa aaacgtcagc gaaaggaaaa atttcgtggt tttttatacc
    15181 tgttcatttg gctagatata aaatccaaac aaatgaacag aagtgcttat taggtttcaa
    15241 ttgggagtat ctgcgctaga ataagagtaa taatgaaaag gagtgttatg tatggattat
    15301 tctagtaaag aatactttga taaaatgacg gcttggtggc gtgctgctaa ttatctttct
    15361 gttgggcaac tttatcttaa agataacccc ttactgagac gtacactgaa accagaagat
    15421 gtcaaaaaac atccaatcgg tcattgggga acgattcctg gccaaaattt tatttatgtc
    15481 catttgaacc gagtcatcaa taaatatgat ttgaacatgt tttatatcga agggccagga
    15541 cacggcggac aagtcatggt atcgaatgct tatttagatg gaagttacac agagatctat
    15601 ccagaagtaa cggaagatga gacaggaatg caaaaattat tcaagcgatt ttcatttcct
    15661 ggaggcattg cttctcatgc agcaccagaa acaccaggtt ctatccatga aggcggagag
    15721 cttggatact ctctttcaca tgcagtcgga gctgtattag acaatcctga agtaatctct
    15781 gctgtcgtga ttggtgatgg tgaagcagaa accggtcctt tagctggaag ctggttctca
    15841 aatgtcttta tcaatccagt gatagatgga gctgttttac cgatccttca tttaaatggt
    15901 gcaaaaatag ccaacccaac gatcttggca cgtaaatcag atggagaatt agcaaattac
    15961 tttaacggac ttggctggga gcctttcttt attgaaggaa atgatccaga aaaattaaat
    16021 cctgttatgg ctgaaaaaat ggatcaagca atcgagaaaa tcaaatccat ccaaaaagaa
    16081 gctcgcctga agacagcaac agatgtcgtg atgccaaaat ggccagtatt gatcgtacgc
    16141 acaccaaaag gatggaccgg tccaaaagaa tgggacgggg aaccaattga aggaaccttc
    16201 cgagcacacc aagtaccgat tcctgtagat caagaacata tggatcatgc agatgcttta
    16261 ctccgttggc tgaaatccta tgaaccagaa aaattatttg atgcacaagg acgtatttta
    16321 gaagaaatca gagaaattgc gcctactggt gaccaaagaa tggcaaaaaa tcctatcacc
    16381 aatggtggaa tcgatccaag accgcttatt atgccagatt ggaaaaaata tactttgcaa
    16441 tttgaaaaac taggctccgt taaagcagaa gatatgaccg aacttggtaa attcgttcgc
    16501 gagatcattg agaaaaatcc agaaaatttc cgtatatttg gaccagatga aacaaaatca
    16561 aaccgattga atcaagtttt caaaacgaca aatcgccaat ggatggaaaa aatcgaacca
    16621 gaaaatgatg aatggctttc gccatctggt cgcgtcatcg acagtcaatt atcggaacac
    16681 caagatgaag ggttcttaga agggtacgtt ctgactggac ggcatggttt ttttgcaagt
    16741 tacgaatcat tcttgcgagt ggttgactct atgttgactc agcacttcaa atggatacgg
    16801 aaatcacatg acctttcttg gcgaaatgat tatccttcgc taaatctcat tgcaagctca
    16861 acagtcttcc agcaagatca caatggatat agccaccaag atccaggaat attgacacat
    16921 ttggcagaaa agaaggcgga gttcatccgt gaatatctgc ctgcggatgc aaatacattg
    16981 ctcgcagtca tggataaagc attccactcg tcagaaaaaa tcaatttgat catctcttcc
    17041 aaacatccgc gtgctcaatt ttactcagca gaagaagcag ccgtcttagt gaatgaaggc
    17101 ttgaaaatca ttgattgggc ttcgacagca aaagaggagg aacctgaatt ggtcattgct
    17161 gctgcaggaa cggaatctaa cttagaagca ttagcagctg caactttgct gctggaagaa
    17221 ttcccaaaac taaaaattcg gttcattaat gtcgtagatt tattgaaatt acgtcatcca
    17281 agtcaagatc cgcgtgggtt gagcgatgaa gaatttgatc aatattttac aaaagacaaa
    17341 ccgatcttat ttgctttcca cggttatgaa acattggtcc gcacgatttt ctttgatcgt
    17401 cataaccatc atttaatgat tcatggctac aaagaaaatg gagatatcac gacaccattt
    17461 gacatgcgtg tagtaaatga acttgatcgt tatcatttgg caaaagacgc agctttaaaa
    17521 atcaaaggaa gtcaagcaga agattttgcg gaaaaaatgg atcagaaatt acaagaacat
    17581 caaaactata ttcgtgaaaa tggtattgat ctgccagaag tattggattg gaaatggaaa
    17641 aatcttgatc aataaaatga taaaatcgat cccgcaaaac agaatttttt acattgatta
    17701 agaaactgaa aaaataaata aaaaaaacgg aaaaaagact ggaagaatgg acagtctttt
    17761 ttttcgtttt tgggaagtga aaaccaaact atttacctgt aagccaccca taaatccaat
    17821 caaatggtgc aaagaaaaaa tcttccattc tattccctcc tttaaaaaaa cataacatga
    17881 tttctattta cgtgagcatg aattttgtta cgtttttatt gccgaaaaat aaaaaccgtt
    17941 cattatgatg tcaaattcgt cagtaattga tgcaatgtgt tataataatt cagttaaatc
    18001 aaaaatgaaa tggagaaaag acatggacgg gttattacct ttatggaaag aacgcggaat
    18061 gacaagtcat gattgcgtat tcaaattaag aaaaatctta catacgaaaa aaatcggaca
    18121 tgggggtacg cttgacccag acgtagacgg tgtgttgcct atttgtattg gaaaagccac
    18181 aaaagttatc gagtatttga cagattctgg gaaaatctat gtaggcgaga taactctagg
    18241 tttcagtaca acgacggaag atcgatccgg agaacgggta gaaacaaaac cagtagatat
    18301 gtctttatct gaagaaaaaa tagatgaagt gatggcttca tttattggtg agatcaccca
    18361 gataccacca atgtactcag cggtaaaagt caacggtaag cggttatatg aatatgcccg
    18421 caataatgaa acagtggagc gtcctgttag aaaggctcag atttaccgtt ttatccggac
    18481 aagtgaattg acaagagacg aagtgacagg aaccatttct tggcgcttcg aagtagaatg
    18541 cgggaaagga acctatgtcc gcacattagc tgtagataca ggcaagaaac ttggttaccc
    18601 tgcgcacatg tctgatctga cccgaacagc aagtgccggt atgtcccaga aagatgctct
    18661 gacattagaa gaagtagctc aagctgtgaa aaatgggaca atcgatgatt gtttgctgcc
    18721 aatagaaaaa ggagtgaaac gattcaaacg agtagatatt actgatgaag tatggcagaa
    18781 agtaaaaaac ggtatgagac ttgattatac tgtatttgcg ctcccagaaa tgccgtcaga
    18841 agaaattgct ttgttttata aaggcaaagt tgtcagtatc tatcagccaa acccgaaaga
    18901 aaaaaacaaa ttaaaaccta gtaaagtatt gagaaatgag gaataacgaa tgaatatcat
    18961 caagatcaga catccttacc aatcagaaca aattccagaa gacgatgtcg ttttagtact
    19021 gggatttttt gacggcgtgc atattggaca ccagaaagtc ataaagacag gtatggaaat
    19081 tgcacaaaaa gaaggattga aattagcatt gatgactttc aatcagcatc catcgattgt
    19141 ctttaaaaag atcgatccta gcagcgtgaa atatttgact agccttaagc aaaaagaaga
    19201 aaaaatggcc gctttgggta tagattattt atatgaagtt gattttactt cttcttttgc
    19261 tcatttagca ccgcaggaat ttgttgatca atacatcgta gggttacatg caaaatatgc
    19321 tgtttccggt tttgattata cgtatggacc aaaagacatt gcagatgtcg ctcattttcc
    19381 tgaatatgcc aaaggaagat tcaaaatcgt cacagtttct aaagaagaag aacaaggtga
    19441 aaaaatcagc tctacccgta ttcgaggatt actagacagc ggacaagtaa aagaagcagc
    19501 aaaactatta ggttgcacat atgaggtaga aggggtagtt gtccatggcg atgcacgagg
    19561 cagactacta ggattcccta cagcaaatgt caaagtaaag agcacagttc atttgcctaa
    19621 agaaggtgtt tatgtatcgg aaataaaaat tggggaaact tggtatccag ccatgggttc
    19681 aattggacat aatgatacat tcggtgaagg acgggagctg actgtagaat tgtatatttt
    19741 ggactttaat caagatatct atggtgaaca tgtcgcagta cgctggaatc aatttttaag
    19801 agatcaagtg aaattttcta gtgtagagga attgattgaa caactcaaaa aggatgaaca
    19861 agcaacagct gaatattttt ctcagcaata aaacattatg cataaaatct cttgtttatg
    19921 tataactagc aatttcaata aaatgggtga taaataagcc caggaaaggg gctgtgacaa
    19981 aagtcttgtc acagcc
//
LOCUS       DAFBSV010000053        19492 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.054, whole genome shotgun sequence.
ACCESSION   DAFBSV010000053 DAFBSV010000000
VERSION     DAFBSV010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19492
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.054"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(<1..1835)
                     /locus_tag="LLB18_001753"
     CDS             complement(<1..1835)
                     /locus_tag="LLB18_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBK5244755.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWR"
     gene            complement(1832..2536)
                     /locus_tag="LLB18_001754"
     CDS             complement(1832..2536)
                     /locus_tag="LLB18_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBK5244756.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            complement(2548..4857)
                     /locus_tag="LLB18_001755"
     CDS             complement(2548..4857)
                     /locus_tag="LLB18_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBK5244757.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            complement(5052..5516)
                     /locus_tag="LLB18_001756"
     CDS             complement(5052..5516)
                     /locus_tag="LLB18_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244758.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            complement(5516..6142)
                     /locus_tag="LLB18_001757"
     CDS             complement(5516..6142)
                     /locus_tag="LLB18_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBK5244759.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            complement(6149..6514)
                     /locus_tag="LLB18_001758"
     CDS             complement(6149..6514)
                     /locus_tag="LLB18_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBK5244760.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            complement(6504..6842)
                     /locus_tag="LLB18_001759"
     CDS             complement(6504..6842)
                     /locus_tag="LLB18_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244761.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            complement(6832..7158)
                     /locus_tag="LLB18_001760"
     CDS             complement(6832..7158)
                     /locus_tag="LLB18_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBK5244762.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            complement(7136..7417)
                     /locus_tag="LLB18_001761"
     CDS             complement(7136..7417)
                     /locus_tag="LLB18_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBK5244763.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETDQ"
     gene            complement(7419..8783)
                     /locus_tag="LLB18_001762"
     CDS             complement(7419..8783)
                     /locus_tag="LLB18_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBK5244764.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            complement(8796..9365)
                     /locus_tag="LLB18_001763"
     CDS             complement(8796..9365)
                     /locus_tag="LLB18_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HBK5244765.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            complement(9337..10524)
                     /locus_tag="LLB18_001764"
     CDS             complement(9337..10524)
                     /locus_tag="LLB18_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBK5244766.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            complement(10588..12315)
                     /locus_tag="LLB18_001765"
     CDS             complement(10588..12315)
                     /locus_tag="LLB18_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBK5244767.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            complement(12312..12764)
                     /locus_tag="LLB18_001766"
     CDS             complement(12312..12764)
                     /locus_tag="LLB18_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HBK5244768.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            complement(12876..13256)
                     /locus_tag="LLB18_001767"
     CDS             complement(12876..13256)
                     /locus_tag="LLB18_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBK5244769.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            complement(13253..13639)
                     /locus_tag="LLB18_001768"
     CDS             complement(13253..13639)
                     /locus_tag="LLB18_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244770.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            complement(13641..13919)
                     /locus_tag="LLB18_001769"
     CDS             complement(13641..13919)
                     /locus_tag="LLB18_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244771.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            13967..14695
                     /locus_tag="LLB18_001770"
     CDS             13967..14695
                     /locus_tag="LLB18_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HBK5244772.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            complement(14841..15317)
                     /locus_tag="LLB18_001771"
     CDS             complement(14841..15317)
                     /locus_tag="LLB18_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HBK5244773.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(15277..15624)
                     /locus_tag="LLB18_001772"
     CDS             complement(15277..15624)
                     /locus_tag="LLB18_001772"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244774.1"
                     /translation="MNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVLKIE
                     QNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIRGGV
                     CEISLVKRLPRTR"
     gene            complement(15611..15796)
                     /locus_tag="LLB18_001773"
     CDS             complement(15611..15796)
                     /locus_tag="LLB18_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244775.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            complement(15797..16069)
                     /locus_tag="LLB18_001774"
     CDS             complement(15797..16069)
                     /locus_tag="LLB18_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HBK5244776.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            complement(16066..16269)
                     /locus_tag="LLB18_001775"
     CDS             complement(16066..16269)
                     /locus_tag="LLB18_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244777.1"
                     /translation="MVKVREQFKIVSDEDNVYKIKIVNINEYREADHKYLVDLYMNDK
                     YLGEGFCGDSLFDDERILKEETE"
     gene            16394..16606
                     /locus_tag="LLB18_001776"
     CDS             16394..16606
                     /locus_tag="LLB18_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244778.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            complement(16639..16833)
                     /locus_tag="LLB18_001777"
     CDS             complement(16639..16833)
                     /locus_tag="LLB18_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244779.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(16841..17029)
                     /locus_tag="LLB18_001778"
     CDS             complement(16841..17029)
                     /locus_tag="LLB18_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244780.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKNLI"
     gene            complement(17026..17166)
                     /locus_tag="LLB18_001779"
     CDS             complement(17026..17166)
                     /locus_tag="LLB18_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244781.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            complement(17656..18021)
                     /locus_tag="LLB18_001780"
     CDS             complement(17656..18021)
                     /locus_tag="LLB18_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244782.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            complement(18061..18363)
                     /locus_tag="LLB18_001781"
     CDS             complement(18061..18363)
                     /locus_tag="LLB18_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBK5244783.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            complement(18363..18662)
                     /locus_tag="LLB18_001782"
     CDS             complement(18363..18662)
                     /locus_tag="LLB18_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244784.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            complement(18655..18819)
                     /locus_tag="LLB18_001783"
     CDS             complement(18655..18819)
                     /locus_tag="LLB18_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244785.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            complement(18825..19094)
                     /locus_tag="LLB18_001784"
     CDS             complement(18825..19094)
                     /locus_tag="LLB18_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244786.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            complement(19106..>19492)
                     /locus_tag="LLB18_001785"
     CDS             complement(19106..>19492)
                     /locus_tag="LLB18_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5244787.1"
                     /translation="NNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQMEKLKTE
                     FPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGRREKLP
                     EWAIDQEAYLKKKALERANRQSKAPF"
BASE COUNT         5419 a         4139 c         3024 g         6910 t
ORIGIN      
        1 attctccaag ctctcttttc tgcatctgtt tttaattcat caggataccc accaggtgtt
       61 tctcctccgc cagatggacc gccattttgt cctggtatca cttctttacc tctaacagta
      121 agttttccct gaatatctaa atcaccgaaa taatatgctt ttccgtttcc taataacaca
      181 aatccttttt ctgcagttgg agaaattaaa atgtattttc catcgccatt tgtacgtatt
      241 accaaagaat tttcctcaag aggtgtaggt gttacagcat ttggaaatgg atttcctgct
      301 gaatctgttg ttccgatcgt tccaatggat tcttttctat tccagaattc catacctttt
      361 ttggttagct ccatgatttt tttgttttca ttccaaattt gaagcgtgcc ttttacaagt
      421 tttaacacat caccataagc attaaaggaa gtttcgaata cttctgcatt tattgttcct
      481 actttgatga agtcagcaac aatttctcct tttgatgtga tagcaatacc gaacgggcca
      541 tttactccgt tgtctgaata acctaagcca tttaaattcc aacgccacac tcgctttgca
      601 ttcgccacat ttggagtatc catgataaga atctctgatg gagctttttc tggacgaaaa
      661 acgacatgcc caccagaatt accagtgatc catgccgtcg cattcaacac attttgaact
      721 aacgtttctg ttcgattgtc gattttcttt ttcaattctt gtgcttgagt atttactgcc
      781 gaagtgtaca gtgataaatc attacctaaa acaatatcct tatatttccc aagcgttggg
      841 aaataagtgt attcgaccat acgctctttt atctcgatat ctagctcttt cgccctaaca
      901 tgagcgacat caccaaagtg taaagacgct agctcttgat acatgtcacc gtattcgagt
      961 gtgtgttcca acgccaccat actgactgta tgagtagctt ttggctcatg gatacgatca
     1021 ttgtcaaata aggttttgcc ccatttgatc aattcatcaa ctgttttaca atctccgttt
     1081 tcacgtttgg caatacgtcg attctcgttg gttactccat caatttctaa ataaccatat
     1141 tcgataggtt ctttgtcttc atcataatcg ttatcaggaa caccgccaac caaatacaaa
     1201 ctattgacaa ttgattcttc atcaatttct tcttcgattg cttctaaatt gatgccaaaa
     1261 tcaatccgaa aaccattatc tgatccaatc tgttttacca gtttcaaatc atagttatcc
     1321 atatcaagtt ccgcgctagt cacgccagtc aaattttgat taccgttatt tgaaccaatg
     1381 attgcttcaa ctggcgcgac ttgtcttgct gtaaattggt gcgttgtccc tacattcgaa
     1441 agatagttaa atttttgatc aaatgccaaa ctgtttttaa gattggtcat gatctgagac
     1501 ccattgccgt tatccgtaaa cgacttgaca ataaagttct tattggccat aaaaccaata
     1561 tgccgagctg ttacagaaac ggaggtcaaa ttctttttga cattataaat ttcaaaatat
     1621 tgccatgatc catctggtac cttcgctttt ataaaatttc ctttttttaa ataagagcga
     1681 tactgtccgc ttcttgaata gttaccataa aaacgatatt ggccattcag cacacgattg
     1741 atttctggca aatcttccca atcaactaac gacgctccgt tcacgctcaa atcatctggc
     1801 atttttttat aagcataaat aaattcttgc gtcacagata cacactccta ttccaaaacc
     1861 gcacttcttt aaattttccg gatattttta cctgattcca ttcaggctgc aatactggcc
     1921 aatcaccacg cgtaaataaa ttcaaacctt cttgtattgc ttttccaagc tgagtatcaa
     1981 ccacgattgt tgcagctaac gtattaagta ttgttaggct tttatcaccg acagcgatcg
     2041 ttatatctcc tccgttcgat tctatttcca gatagggatg tgcaatttcg tcaccatgat
     2101 caaaaatatc cataacacta gaatgaaaaa ttttaggtgc ttcaccgatt tttcttttga
     2161 gtggctgaca acgaaaagta acatcgaatg tataaaagaa gccccactcg ttttcgaaag
     2221 ggacttcttt atccatgctg cagatagcct ctagatactt gtctggatca ttatgtgtga
     2281 ttaattggct tttaccagtg agccatcgtt tgacttctct cagtttcgaa tgtggaatag
     2341 tgatcccttc tatttccaaa tcaaaaggtt catagtcatc aaacgtctcc gtcaattctc
     2401 cgcttcggcc ctgaatcgtg taagtttcgt atcgcttgtt cggcataata tctggaagct
     2461 ctgcctcaat gatgcaattc atatcaatta ctgcattccg atttttccaa ataaaatttg
     2521 gttcatctgg attcataaat tgtcgactca aataggaaca cctcccaaat cacgaatagc
     2581 ctgtttgttt gctttagcaa atttacgatt catacgatct aactcagatg gattgtttgc
     2641 atcgactttg ccaatgtgta tatgctgttc aatgctacct ccagaaactc ttccactgat
     2701 ccctttgcgt ttttcttcgt ctgataatgg agtaactgtg gttttaccat tcttggcagt
     2761 cagtaactca ggtccagctt caccaacaat cgcttgtcca ttgattagat gaccgccttg
     2821 tgctaaataa ggcagttttg aaatagaaaa tgattttcca cctacaccag gaacccattt
     2881 tggtatcttt atattattca atccaccaat aaatccattg atcaatccaa tcatggcatt
     2941 aataggagct ttccctacag caacaatacc atcgaaaata cctccaaaaa tatcaactag
     3001 accttgccat gcttttgacc aattccctgt aaatactcca gtgataaaat ctagaaaacc
     3061 actgaaaatt cgttttccag cattataaaa attattgaaa tttgctataa caccatcgaa
     3121 aaatccacca aaataaccac ttaaaaaatt aaatatttca acagctacat ctgaaacacc
     3181 tttgaagaaa gaattcactc catcatgaaa ccatttaacg ttattatatg cccaaattag
     3241 tccagtaact aatgcgccaa tagctataac tgctaatgca aaccagcctc ccgacattcc
     3301 aaataaacca gcaagtcctt gccaaactcc tataaaactt ttaacttccc caacgatttt
     3361 tgtaacagat cccataagtg aaccaagaac gattagtact ggtccaactg ctgccgctat
     3421 accagcaatt gttatgatcc aattctttgt atcttgatct agagaccccc accatttaga
     3481 gaattcctgt aataaggaag ttgctttttc aaaaaaaggc aaaaggctta cttggactgc
     3541 ttcacctacg tcagccattg ctaattttgc attgttcata gcttgatcgg cttgatcaat
     3601 tgggtcgaga gtagcatcga atgtgtctcc tacagctccc ccactttctc cagcagtttt
     3661 tgctaaatct tccaggttca aagtacctct acgaattgca tcggccattc taggaccgcc
     3721 tttagtcccg aatacttctg ctgctgcatt gatggcttct gtttcagaac ctgcattttt
     3781 taccttgtct tgtagttctt ctagtccttg acttaaagat tttccgtctt tcgcataagc
     3841 cactgttgct ttagataaac tacttaaagc tgcgcttgaa tcaacaccag attgctcaaa
     3901 ttgtccaagt aaagtgaccc cttcaccaaa gctcaaccct aattgtttaa tttgtggtgc
     3961 gccatcaatt gctttttgca tcaagtcgtc tacagattga ccagtattct gcgatgtttt
     4021 cgttgttaca tcaaggacag aattcaaatc atcatattct agtccataag catcaatagc
     4081 ttgtcgagca gatattgctg attgcgaaac atctgtatca ttgatttcag cgtactgtag
     4141 gagataattg gttgaatctt ccagtttttt atccatgaat ccaaattgtg tatttacctc
     4201 accaatagct tccccaaccg tttgtaaagg taaatgagta tttgaaccaa cgtttttgaa
     4261 agactgtgaa agtctatcag cttgatcacc tgttgctccg gtttttgtaa tgatggtatc
     4321 aagtgcctcg tcaacttcac caaatgctgc aagtcctgct gctcctgccg ctacaatagg
     4381 cgcggttact ccaacagaca ttttttcacc aacgcctttt actttctcac ctgtttcttc
     4441 gattttctgg agtttttttg ctgtatcaac agaaacgtca ccttgttctt taagtgcatc
     4501 gttcgtctgt tctaatgctg tacgaagttt attttctccg gtttcagaat tgagtaattg
     4561 tttataaagt ttttctgatt cagcagaata ttcaccggtt tctttgacag atttttcata
     4621 ttcctctctc agcatttgag atcgttgttc agccaatcct aattgttttt ctaatttttg
     4681 tttagccgct cgcaattttt ctgtttgagt tgcatccttg tccatcgcag acacttggtt
     4741 tttgtactcg gcagcggcta agttcatttc tttgttgatt tctttgattg ttttcgaata
     4801 actgacttcg ccattcgttt taaaattaag aacgacatca gattctttac cagccattta
     4861 tcttagcgct cctttctacc accaaggcga tttatccata gttacagatt gaggtggttc
     4921 aaaatcggtg ttttgttgta accactgtaa ataagatttg agccacaagt taggtgtaga
     4981 ctttaaaaag aaactctcac tccaattcaa tagagtgaga gcaacgtaaa tataaaaact
     5041 ccaaggagtt cctatctctt ccgattcttt ttgtttttct ttctttttgc ttgcgctttt
     5101 tgaaagtctt gtggcttctt ggattttttt aggtcttcca cctgaaatgt ctggctagca
     5161 aaaatttcca tacaggtact ataagcagac aacacctctc cactcattcc caaaaatttg
     5221 aaaatagttt ctggatcttc ctctaaacca ccagtacgca gcatggcata aatcaaggca
     5281 cgcatgattt ttagatcact aggcgataag ttagcagaag aaatttgtcc ttctttttta
     5341 gatagcatgg cgttcatatc agattcaaat tgcgaataat ctccaccata cacatctgct
     5401 ataaattcca tcgtttgcat agtaaatgaa atagggaatt ctgcgccttg aataattaca
     5461 acagcagaat tttttaagtc ttcaacgtga attccataat cagataaccg agccattaac
     5521 ccgcacctcc aactttagcc aatgttttcc actgttcttc atcgtataca ggttgagcaa
     5581 tgaatttatt aaataattct agagaagctc cgtctctatt tgaatcaaaa cttgcataca
     5641 tcacattatt gtatttcagt ccgatggaaa ccagatttgc agttacatcg tcaatttttg
     5701 tttcttcctc tgcagtggca tactcttcgt caatcacatt ggatagttgt gtattaggat
     5761 accaaactgc ttttttaccg ccattttcaa tatttccaat aaatccaaag gcgaagtacg
     5821 gaaattctcg tgcggtattt ttgctaaacg ttactccgct tttagcaact aatcctttga
     5881 tttcatccat cacttctatc ggaataccca cgtgatccaa cgcaagttca tgttttgttt
     5941 ctcgcgacac acgacgaaac attttgctgg atgcccattt ttctaatgct gttccattcc
     6001 ctttgacacc gatttttgtg gcaattggca atcgtaaaac ttcactataa gtcggtgcag
     6061 ttccaacaga atctggcgtt gccatcatcg caattaaaat gtcgtccaat ccttcaaaat
     6121 aaaaagtatc ttgttttccc aattaaaatc acccttccca taaatcaagt atttttctag
     6181 tcataatttc ttcaattttt tctttgtttt gttcatacgt accacttgca aaatgttggg
     6241 cacgttgatt tgttgtgcca ttttcggcaa agcgccagta aaaggccgtc tcttcaaatt
     6301 gaactttcac ttgatcgttt tcaactacta cttttatttg atcgcgcata tgtttctttt
     6361 ttaagagcga cttaggaata ttaggaagca actgctttag ataaaagtta gctgcttctt
     6421 ctaaagattc caacgataat tttttcggat caacttttga aaggtttcct aaataatccg
     6481 atatttcaga aaaaccattc ttattacttg gcattttcca cacacctcac atatgtgtaa
     6541 tagttggtta cggtatcgtc gttctcatca ccttgtatac ctgtaaaatc tgaatatgga
     6601 atgccagcat tttgcagcgc ttgttcaata acaactaaat cctgttctgt tccaagtgta
     6661 aaaaaagaga cttggtaata aggtaatttt ttatagactt taccggatgc catttttttg
     6721 ctgttactca catttgagta cacaatgtat ggatacatcg tccctaatct ggctttgtct
     6781 ctgaacactg ctaactttgt tgatttcagc gctgttttca attcatcaaa gctaatcgac
     6841 ataagctaaa ctcaactcca tttctcttgc atcgggattc gtataaatgc gagtaatgtt
     6901 atacgttaca gaatcaattt tgagcgcact taatttctct gtgatggatt tatcccatct
     6961 gactttaatt cgtctgacaa cgtctgtctt ggcttgctgt gataaatatt tttcttgaga
     7021 agtcacaccg agttcttcat agaatattag acgcttaaat tcgtaaattg tagttggacg
     7081 atcgtttccg tctgttcctg ttttgatgtc tagcaattcg gctttccatc tgagattatt
     7141 ggtctgtctc ttcggcattt tgaatcgctc cttgcacgat aaatggcgtc atggcattca
     7201 tagctttgtc gagttcatcc tctgaaactc tatattcata ggcaatgccg gcaaccatca
     7261 aaataagata ttcttgttgg ccaccagttg ctgttttgac ataatctttt gccatattta
     7321 aataaaaaga gagcaaagaa tcatccatgc cctcttcaaa atgaatatgt gatttgaatt
     7381 tttcctctaa agacaattct ttagtttgct cttccatctt aaccaccaac tggttttgta
     7441 atttcgtagc gatatactgc cggttcaaat ggagaataaa ccaattgacc atctagcaag
     7501 ttgtaaattt ggaatccaat ttgattttta ccagagaatt tttcaacaag tttttgaatt
     7561 tccaaggcac caataacttc ttgaatttta aatgcagaaa aatcgccaaa atataaaact
     7621 ggcgtgtctg gttcaccctt tttatctgct gcatctgtcc aatccacagg atagccaact
     7681 aattggtaac caattccacc ttctgcttgt gtgaatggcc gcaacaaagg aaatccatca
     7741 tctgttttca ttttttcaat ggcagtcaaa gcagctcgat taataataaa gcgtcccttt
     7801 ttcatcactt ctgtcactgg tgtattttta aattcgatta atgcatcata taatttttgc
     7861 ccagcacctg aagcagttag atctaaaggt tttttaaatg ctacagcctt tttggctaat
     7921 gcaccaggat tttcatttcc agcgtcatca ccattgaaca tataattgat ttctttacgc
     7981 acataagctt ttttcaattc ttccacaaca atatcttcaa ctggaacacc agacattttt
     8041 aataattttt tagttactgt tgccaaagca tcgaattcgg caggattaag caaaatttca
     8101 tcaaactgaa tagctgtttc agcaatatca gttgaacgct ctttcttgtt tacattcgca
     8161 tctgctttct tcacaagaat tggatatttg acatctcctg atgttcgcac cactgttccg
     8221 tatttacgaa gtaaattttc ttcttgagca taagtaataa cttcagatgc aattacttct
     8281 gggacagtaa ctgaaccgtt gccagcttca atccctaaag ctcgagcttc tgcttcagaa
     8341 atatttccag ctacaaaatt agcaaatgct tttcgtagtt gttgatcttt ttgtttcttg
     8401 gtcatttttg cacgtgcctc caatccgttc ttaattgatc caagtaatcc atctcgttgc
     8461 tgttgagtaa tcattccaga acgattttct gaactatctt cactgtctga atcttcttct
     8521 tgatcgttgt cttcaccaga acggctttcg tctgaatccg tactattcga ttgatcatct
     8581 gtattgtcgt ctgtttcatc agttccagaa tctgcgccta attcgtcttt aattccgttc
     8641 aattcatcaa taacactgtc aatttcttct ttcacggctt ctaaatctgc ttcgcgtaat
     8701 tctcctgatt caactttttc acgtaattca gtcaatcgtt gctcacgacg tgccttcatt
     8761 tttttcaata attctttatc catgtatttt tcctcctacg cttctagcgc ttgattaatt
     8821 tttttgatta atttttttct ttcttcgacg tttttttcta attcatcacg acttcttaat
     8881 gcagcttctg tatcttcgta tgctggcaaa ggcacaatag aaacctcgta taattccact
     8941 tcatggattg ttcgaagcat tggttcagaa ttgtagtccc acgtttcttc agtcggcaca
     9001 aaaccaaaac tacattggtt gatgtctcct cgttccatag atttaactaa gtcccttgct
     9061 accgttgtgt ccggtaaatc aacttcgaat ttcaaaccac gttcatcttc ttcaaggcga
     9121 agggttccgc ttttagtacg tcctagcaca ttggaccaat cgtgattgaa caaacaacga
     9181 acatccgaat tactaattgc ctttgagaat gcaccaggaa caatcacttc gcttaagtca
     9241 tcccataaaa gtgtttgact gttgaataca gcagcgtagc cgctaatggt cctcgtatga
     9301 gtttcttcat cggaacgtgt tgaaagattg gtgatgtcaa tcgtgcgaat ttccttcttc
     9361 ttcatttcca tcacctcctt tcaagtcttg atcattcgtt ggtaaggaat catctgttgc
     9421 atttttctgg ccaatcctag ataagtcatt tgaaatatag atagcttgtg tttctggagt
     9481 attctgttta ggaaaaccaa gcatttctgc cacgttatct ggacttgtaa tcccggtacg
     9541 aacgatgttg tagccaatat ttgtttttgt tgagtaagga acaaaatcca aaatattaat
     9601 tttccattcc actctatagc cagaattagg cataaaaaaa agagcggtgt aatgttcgct
     9661 cttgtttttc aatattggtt tgattgcttt gttgtgcaga tacatcatcg ctttttcaat
     9721 atctgtcttc atcagcgatt gatacgtatc aacattgatt cctagaaatt ttcctaagtc
     9781 ttttttgtaa acacctaaat aattcaaaat tgccgcgtca tcaacaggac tttttaatgt
     9841 ctcgatggaa tatccttttc ccaaaggaat catcttaaca gaatgatcac tctcattttg
     9901 cgttccttcc agttgatcca atatagcttt gacaattttt gtttgggcgc tattatttgg
     9961 attgatgtgg gcgtctagtt taagcatgaa cgcaagtaaa ccgcctttag tatatttgtc
    10021 cgtcaaaact ttttcagcgc tcagaacgcc ttctagagtg tttcttgcaa gatcaattat
    10081 tccagcacct tttaatgaat cagttccgat gttcttaatg tgtcgaatca tttgaccagg
    10141 tattttttga ccattcattt caaattcttc ttgaagtcgt tcattgattt tagttgttac
    10201 accgtacgcc aaatgaagct gatccctatc cgttaatggg aatgtctcac cattgatcaa
    10261 taaagtattt gtttccaatt tggtaaattc gaatcctgtc aaataatcat tgggactctt
    10321 caaaatattt agtaagtgat gatctttgac ttcgttgccg tcgggaccaa taacaattgg
    10381 tgtggccaat gccacctgat tagatatgtc ttgaactaat tcataaacat cagaagattc
    10441 catgatagat gaatccgtca catatctttg accataacgt gtgtagtgtc caaaaatatc
    10501 ctcgatatat ccacgttttt ccataaaaga atagactgca ttcgataacc gatcacgtaa
    10561 tttcaatttt tttcaccgcc tttctattta tctatagatg gaacttaggt aatcatctaa
    10621 ctcatctgaa tcaatatctg tcatttgatt catcgtttcc ttatgaccac acaaaaacgc
    10681 cacgaaccca tcaatctttt tctttgattg acgtttactt ggcgcttttt gtccattgat
    10741 gttagtaatt gctacaacgt tcaaagtgca ataaaggaat aatggattat caaattgaat
    10801 tcgtttctca taaaacaacc gttcgacatc gtcaaaagga gcattcaata ctttaggata
    10861 ttgagcaact tcaacgcatt ccaatcctaa gttttctaat ttctcaacaa gtttgtcact
    10921 catcgctgga tcataattca cttgctgaat atcatataaa ttcatgcagt cctctatgta
    10981 ctgcaaaatc tgatcttgat caatcatttt tccgtcgcaa aattcaacga aaccttgttc
    11041 agccaaatca ctgtaaggaa cattatcttc tttttctcga aactctaaat cttcattcgg
    11101 aataaaataa agttgcttta ctttaagaac cgctttacca tcttcatccc atgttgggaa
    11161 gtttaaagat acacaggtca aatctcgtgt acgtgataaa tctaaaccga tataacatgg
    11221 ttcgccactt aaatcaccaa gttcttgtgt ggtaactaaa catggctcta cttgatcctg
    11281 ttcaaagaaa ttatccgcgc cgttcacaaa tacatccaag tgtttcgtta gaaattcagc
    11341 tttggaatga gctgaccgtt gcgctgtttt aaatgccgat tctaaagcag ataaatcgac
    11401 tgatattccc cagttaggat tgcacatttc ccagactttt ctatccgtcc aatcataatt
    11461 tttatttggc tcatagatta gaacaaagtt tgaatcatta tcatcacgtt tcaacacttc
    11521 ttttgcttcg cgatatacac gcattccaac agacgacgaa cctttcccag cagttgagat
    11581 attaaacatc aatggctgtg gtaaagatat ctgagcagac ttaaaattgt catactgttc
    11641 cattttctcc tgtttatgca attcatcgtt caatacaaaa tatggattgg atccctcgat
    11701 attatcaata ttcttggttt gaacaataaa tttatttgag taagccatat cttcatgaat
    11761 atagtcataa gtaatactag aaacagttcc ctttggcccc ctaaatattt tagttccttc
    11821 aagtaggatt ggattgttta agattgtaac tgcaaaaggt ttggcagcat attgcgcttg
    11881 agcaaaatca gatgcgcaag catagcaatc aactgataac gccccttctc cgtacattgc
    11941 atatcctaat gaaccgacag caatcaatgt tttaccattc ttttttggaa tctggacata
    12001 agcctcacga gtaacgcgta caatttggcc tttttcattt tctttaaccc aaccataaat
    12061 ccaagaataa ataaattttt cccagggttc taaaagaaac ggttttccca ccatttctcc
    12121 ttttgtgtga acaataaatg attctaccca atccatcatt tcattcgcgc gatctacatc
    12181 aaaccaaata tcttttcttt ttttccactg ataccagcga tctattgcta aacgaacggt
    12241 cttaggatac ttcttaggtt tctttcttac ttcttttgca aataaatcag cataatttac
    12301 accaggttca atcatttttc agcacctgcc ttcttacgcc atttatttct gtgcgctgct
    12361 agttcatcta ctggctttac ttctgggcgt gtaatttctt catcttttct tgcggtcgat
    12421 cctccagcaa ttagtctacc agtttttgct ttgtttgtta atcctaataa atctagagct
    12481 ttcatcttct tatctgccca agtttctact tgttgtgcca atggatgttt tgattgatta
    12541 gtagctcctg atttattcgt gaatttttgc gtctccggaa atcctttttc cttccacaat
    12601 aaatatttgt gttggtaaat ttcaaaaata tccaagtatg attcgattaa tggatcaaga
    12661 gtgatggtgt acaaatcaga caaattcatt atttctaaga tacgagcttt ttcagcactt
    12721 actttttcat caataatcgc tttacgttgc gctttagtcg tcatttttgt atacaccccc
    12781 ctttgttttt tgaaaaattt gacctaacga tgcgcgtgac tccccgctac cctatctccc
    12841 cacgcgaaaa aattttgaaa atgaataggg gggcttcaat tgaaatacga aggaaaaact
    12901 tttttgtctt ccgtttcgtt ttcaacaatt ggatgacatt ttgaacataa tagcatgaga
    12961 ttgtttggat caagcttaag cagttcgttg tctttgattg gtacaatgtg atggacgtgt
    13021 gctctctttc caaatatgaa ctgaccacac cgctgacaat gaccaccttc tctttcataa
    13081 ataaattgac gcatatcttt ccatgcttgc gttcgataga atggtttgtt ctcatgatga
    13141 taaacagact ttgcttgctg cttcttcttg cgtgatctgc ttgatctctt gtgttcagta
    13201 cagtagatac cctttgctat tttgttcgtg catccgtcaa actgacagta tttcattcta
    13261 cttcacgaat aagatttatg atatcgcctt ttgcacggat agcaccagga atatcaatac
    13321 catgtttctt agcatatgca cgcaattctt ttgcagtcat attgtccagt tcatccgtat
    13381 cttcagtgga ctgatcatta gtagcttcgt ctccatcaaa attagcagca gtgtttccat
    13441 cgctatcaag aatttcactg ctatgagcta tgagttcgcc attgacagca acaaatgatt
    13501 tgccatcact caaaattcct ttttcttctt ttacttcaaa atttggttct tgatctttcg
    13561 gaacaactac tgtccttttc ttttctgaat cccaatactc tgttccacta atggatgttc
    13621 taattttgat cattgccatt ttaattctct cctttgtaat ttgtacggat tacttttgcg
    13681 cccattcgct cataccattc aatcgtttcc tgcagattgg gtagagtgtg tgacaataaa
    13741 gaaataacta acgtattcat tccagttctg taatcatcat tctccacttg cacatgtgca
    13801 tgattaccat tccaattttc tctgtacgga ctattctctg cttcaattgc tttcttataa
    13861 actttagcca aacttgattc tacttcaata ctaagtaccg cttcatgaaa atcattcatt
    13921 tgtttactct cctatcagat attttgtggt atgatttata aaaaagatgc gaggtgtttt
    13981 aatgcttcaa gaagttaata ttaagtatcg tgatcgtcaa aatacagaga caatttattt
    14041 gccaaatagt tgtccgcatt gcggaaatat aatgactccg tatgtgtatt ttggggtttc
    14101 atcatatagt gcgttcgata atgatagaat ctttggcgta ttagtacagt gtataaatga
    14161 tgagtgcaac aaattttata gtttacaatt tataaatacg tttaatgaag atgaaggata
    14221 ttctgaaaat attttaatta aagattatta ccgtccgccg attaaaatag atttaccaga
    14281 aaatattgaa aaagtttctc ctacatttgt tgatatttat actcaagcca cacaagctaa
    14341 atctgagcaa ttggaacaaa ttgctggagt tggttataga aaagctctag aatttctaat
    14401 taaagattat gcaatatcta aaaattcaga ggatgaagat aaaataaaaa aaatgttatt
    14461 aggtaaaaca attgaaaatt atttgaatga ttttcctaaa ctccaaagat tagccaaagc
    14521 tgctacttgg attggtaatg atgaaacgca ctatgttcgt agacatacta ataaagatgt
    14581 tcatgatatg gatgcattta ttaaatcagc agcgcaattt atcgcggctg attatgatgc
    14641 tgatttagct gatcaattta taaatggaaa taactttatg ccaactacta attaaaagaa
    14701 taaaagagcc acagatacca attaataaaa cggttgggat atcttggctc tttcatattt
    14761 ttttgacact aatagaatat catgctgcta acaatgttta catagctaca atgaccgaac
    14821 atttagtgaa cagtgtaatt ttagaataaa gagagttgtt ctttgtactt ctcgctattg
    14881 taaaaatcaa tttcgttttc ttttttcaat cggtcagctt gtctgtgttc atactcatct
    14941 aaaaagttca atgtctttct aatttctgca tgtcgctgtc tgacatacga tgagctatac
    15001 ccaacagatt cagcaatatc ttctaagctc atttgatcaa catatttcat cttaacaatt
    15061 tgattatcga taccagaaaa gctatctatc agcaataaca tttcttcttt ttgctcgatc
    15121 aacaattcca attcattttc tatcttttgg atattctctt ctaaagaaga agttctcgaa
    15181 ttcttttcga tgcggacgtt tgctaaatca ccacagaccc atcgattcaa ttcaagctta
    15241 cttttattaa gattccactt taagtaaaga atctgctcat ctagttcttg gtaatctttt
    15301 aaccaatgaa atctcacaaa cgccacccct tatggtagaa tagtattgcg ctgctatctc
    15361 gaaaggggta gcttttttat tttttcttag ccgttccatt ctggattgcc ttttgttcca
    15421 aacgtcgttt tttcttctta atctttgatt ttgtttttcc catacaattc tcctttccga
    15481 aaacacattt tgttcgattt ttaatactaa ataaaagttg gccagaattt ttcgttcgtc
    15541 tttactcatc tttttttgaa taagattact agcataaaaa tagttagtac cacgaaaatg
    15601 aacaggtaaa tcaattacgt tcaccttctt catgccagtt atcagccact agaatctttg
    15661 cgttagtgcc gccaccgttt tcttttttgt atttttcaaa tgctttataa gcagctgttt
    15721 ttgatttata gatttttccg gaaccgactg ggaacatcca tgtgccctct gtgatagcta
    15781 agatgtatac tttcatttaa ttcacccctt taatccccaa cactacatat ccggacttct
    15841 gcatgtaatc agtaatataa gtgatctctg ctttgtatga gtcaccagtg taactaaatg
    15901 ttggtctcgt tagtccaggt aattcatgtt taatgtattt tttatattca cgtagtatta
    15961 actgatcacc aactttgaag tcacgatcat tcttgcggat ctcgaattgt ttgcgtccgc
    16021 tcgtcactgc ttcaaaatat tctggtagta tttttagttc gtggatcatt ctgtttcctc
    16081 cttcaaaatt cgctcatcat caaaaagtga atctccacaa aatccttctc ccaaatattt
    16141 atcgttcatg tataagtcaa ccaaatattt gtgatctgct tctcgatatt cattaatatt
    16201 aacgatcttt attttgtaaa cattatcttc gtcgctcact atcttgaatt gttctctgac
    16261 tttcaccacc gttcctcctc tttttgaaaa aattttagtg tttttgtaag accccctaaa
    16321 tcagcttttt tatttgatat aatacttgta tcgattaatc aaatcgaaat taaatttaaa
    16381 aaggtgattt atcatgaata tcaacaattt agtaaaactc gttgaacaac gttttaaaga
    16441 atcaggatta gaacaattaa aaaaagataa ttctccagaa ttattttcta attttaccga
    16501 agacgacatt cctactctta aacaattaaa atattattct gattattgga cgcaaactcg
    16561 tgagaatgaa ttaaatttag aaaaactcat tattaaaaag aaatagcaac tccagcccac
    16621 acggctggtt ttttagtttc aacttccctc cttacgggtc aaaatcatcg gttccggcat
    16681 aatctgatca tcctttagca acaaatcagg atattttttc cttagcttct tattgttcgt
    16741 gtaagttttc aatagccatt ggttggcttc gcttttgctt tctccagaaa aataaatttt
    16801 ccctgtttgg atgcctgcaa gttgaatcat cattttcacc tcaaatcaaa tttttttctg
    16861 ctagatggag caaaagcaat ccgacatcaa gaatcttttg acccattatt tcagctactt
    16921 tgctcggctt aactccttga gaaaagagca agcgtgcttg ctctatctct tcgtgagtcc
    16981 aaataaattt ggcttcctca aggataatta ctggatcagt tgctctcatt gttcctctgg
    17041 aaaaatgatg tcattcttat gcttggacca ggtatctgca tatggaacaa agtattgtct
    17101 agctaattcg atttgatcaa ttaaagcagt ttctgataat tcatggtctg cagcaatttc
    17161 attcatacta tcgccttcat ctaaacagat aagaccgttg acgttatcga tttttacatt
    17221 tgtgactgct tgactttctc cacgctcata atattctaca gttgatactg atacatcagc
    17281 ttcggagttt aattgcagaa tctgttactg ccgggataat ttaatattct tttcataatt
    17341 cacctttttt cctactgaca tcgaatattt ttcatgttat gattagccgt gaaaggagag
    17401 ctatattatg tgtttacaca tgatgtcctt agctcattcg gttctttgga agcttttttg
    17461 gaaataactc tcaggttctt gacgcaaatc tcatttattc tttgaaacaa aaaacttcca
    17521 ttttccgaga gctttggatc acttcaaaag agatttgcat ttatatttct gtgaccttga
    17581 gtcgcgtaaa gaaccttaca gcaatggcgg caattccact ttcaggaaac cgcctttttt
    17641 cattgatatt ggtggttagc ggactaccca ttttctttcg gcagtgccaa accacaaatg
    17701 atctgtgttg atgtttaggt agttgtatac cagataagct aaatccaaag tgcctgcatc
    17761 ttcaagacga caatattcca aaaattctcc catagctgga cataaaaatc ctggagctat
    17821 catatcccaa cagttaatag tgcaaagaaa ttcgtttagc ttctgaacgt tttctttggt
    17881 ttcacgaatt acaacatact ccaattcttc tccgctggca gagcattcca aaacttcaaa
    17941 ttgattaaga aatggtagaa catatgcttc aaacatcaac attccatctt tctgtttttg
    18001 cacttgtttt gcatcaatca tgtctatcct cctattcagt tatttcttcc attaatggaa
    18061 ttatttcagg tcactggact taacgaaaac accattgacc atctttccag tccgaccttt
    18121 gatttcgtca taagcaaaat ccaagcactc gtataaatcc atatcatttt gcattgccaa
    18181 gatgatcaag gttactacta catcgccaat tccgtctctt aaaccatgtt catcttttct
    18241 agctagagaa gcggcaactt ccccgatttc ttcgaccgtt tttaacattt gcttgctgaa
    18301 atccgcttga tccaatccct tatcttttgc ccactgctct actttcgcga ttagttcgtc
    18361 cattatttct cctccacata cctaaactgt cttccttttg aatcaatcca taagctccta
    18421 gctctatccc aaataatatt tttgctcaga ccagtaattt cagataactg tttagcggta
    18481 cccgttacta gaattcgatc accatgccag attgcaatct ttctcggcgt tctccgtttg
    18541 ggcttttcag tccacattga tttaccgagc ttttggactt ctgcaactat ttttttatct
    18601 tcctgccaat cttctgaata agtcaattcg ataattcgct gcattgccgc tttcttatcc
    18661 atcccgacat tctcctttca gtaatttgag tacttgatca agtgcgctct cacgtccgcc
    18721 atgaaatgtg ttgagccact tgtcttcgta cgacacactt tgtcttaaag cttcttgatg
    18781 cattaattcg atctgtgctg taaatgtctt taggtccatc ttgtttacac ctgctcaagt
    18841 tcattaagat gtttttgcaa gcctttaaca caatcaatga atagtaattt ggtatatgct
    18901 aaatttctta attgcgttcc atcgatatag agtgcgaaat agtatctgag tttactccaa
    18961 ctcgaacgat cattcttaat tccttcaatt ccagcttctt cgagttgatc atatacgtct
    19021 ctcaggacgt ctaattcctc gcccttttta taattcgcta tttcattaat tagttctaga
    19081 taatcgatct tcatttttcc acctcttaga atggtgcttt tgattgtcta ttagctcgtt
    19141 ctagcgcttt tttcttgaga taggcttctt ggtcgattgc ccattcagga agcttctctc
    19201 gtcttcctgt gcgcttgtat ccactgcttg cgttcttagg ttcacttttt tctttccttg
    19261 cccaacttcg aatagttgcc aaatagtttt tataagtctt accagatgat tcacaatact
    19321 ctgacagtcg ttcgattcgc tcttggtaat cattagggaa ttctgttttg agtttctcca
    19381 tctgctcatc tgacaaaaga acatttttat actctccgta tttatgacgg acgggcttag
    19441 ccttcgattt tttcgaaggc ggtaactctc ttatatattc ttttgtatta tt
//
LOCUS       DAFBSV010000054        19223 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.055, whole genome shotgun sequence.
ACCESSION   DAFBSV010000054 DAFBSV010000000
VERSION     DAFBSV010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19223
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.055"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            168..362
                     /locus_tag="LLB18_001786"
     CDS             168..362
                     /locus_tag="LLB18_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244788.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..930
                     /locus_tag="LLB18_001787"
     CDS             631..930
                     /locus_tag="LLB18_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244789.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1027..1461)
                     /locus_tag="LLB18_001788"
     CDS             complement(1027..1461)
                     /locus_tag="LLB18_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5244790.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1693..2403)
                     /locus_tag="LLB18_001789"
     CDS             complement(1693..2403)
                     /locus_tag="LLB18_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBK5244791.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2393..3253)
                     /locus_tag="LLB18_001790"
     CDS             complement(2393..3253)
                     /locus_tag="LLB18_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HBK5244792.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3258..3896)
                     /locus_tag="LLB18_001791"
     CDS             complement(3258..3896)
                     /locus_tag="LLB18_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HBK5244793.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3911..4210)
                     /locus_tag="LLB18_001792"
     CDS             complement(3911..4210)
                     /locus_tag="LLB18_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5244794.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4253..5737)
                     /locus_tag="LLB18_001793"
     CDS             complement(4253..5737)
                     /locus_tag="LLB18_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBK5244795.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5757..6218)
                     /locus_tag="LLB18_001794"
     CDS             complement(5757..6218)
                     /locus_tag="LLB18_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK5244796.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="LLB18_001795"
     CDS             complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="LLB18_001795"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HBK5244797.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7521..8291
                     /locus_tag="LLB18_001796"
     CDS             7521..8291
                     /locus_tag="LLB18_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBK5244798.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8564..9391)
                     /locus_tag="LLB18_001797"
     CDS             complement(8564..9391)
                     /locus_tag="LLB18_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5244799.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9959..11194
                     /locus_tag="LLB18_001798"
     CDS             9959..11194
                     /locus_tag="LLB18_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBK5244800.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12193..12453)
                     /locus_tag="LLB18_001799"
     CDS             complement(12193..12453)
                     /locus_tag="LLB18_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBK5244801.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12480..13781)
                     /locus_tag="LLB18_001800"
     CDS             complement(12480..13781)
                     /locus_tag="LLB18_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK5244802.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14073..14531)
                     /locus_tag="LLB18_001801"
     CDS             complement(14073..14531)
                     /locus_tag="LLB18_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK5244803.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14544..15875)
                     /locus_tag="LLB18_001802"
     CDS             complement(14544..15875)
                     /locus_tag="LLB18_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HBK5244804.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGRDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVNAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15886..17328)
                     /locus_tag="LLB18_001803"
     CDS             complement(15886..17328)
                     /locus_tag="LLB18_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK5244805.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(17315..18079)
                     /locus_tag="LLB18_001804"
     CDS             complement(17315..18079)
                     /locus_tag="LLB18_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HBK5244806.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18183..19058)
                     /locus_tag="LLB18_001805"
     CDS             complement(18183..19058)
                     /locus_tag="LLB18_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBK5244807.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
BASE COUNT         6114 a         3949 c         2949 g         6211 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa atcatgtgtt cattttttat attagttcga atttgcaaaa aattgtattt
      901 gataaagagg tgagtaaaaa aataaaatag ctgagcattg gaggatagat tgagtgatac
      961 taagtctatc ctcttgtttt tctaaagaac taagctagaa ttttttcttt tgtacgttat
     1021 tatatgttat ttgtcattac caaaaagcac cttttttctt ctagtatcta tgacataaga
     1081 aataccaccc atttccttta cttgaacaaa tcctactgat tcataaaatt tttttgtttt
     1141 ctcagtatca tctgtcaata attcgatttg gactggtcca taactagtga tcttctccaa
     1201 agcttcattc aaaagcactt tgcctattcc ttggcgctga tacctcggat gaatgaggat
     1261 atcttgaata aatgcgatcg tcgcaaaatc agtgatccaa cgaacgattc cgataatctt
     1321 cccttcccca ttacgcttta tcagagattc agattgttca aatgctctag ctaaccttgc
     1381 agtgtctttt gtgtaattcg tccaaccaac gctcttatat aattcagaaa tctcatcgat
     1441 cataagggaa tcaatattca tttttttctt cctttcttat acaattctcc ctctaataat
     1501 acagttcttt gactatttaa tctatcacat ataactctcc tgtaaagatt ctctcgattc
     1561 cttaaaattc ctctttcctt ttagaatgca tactttttga taaataaaaa ggttgtgata
     1621 aattttcttc acaacctctg tttctctcta tcaagtgtta tcttttaatt ttctaccctt
     1681 accctagcat ctctattgcc cgtagtatgc atactttcca tgtttgcgaa aataatgttt
     1741 atctagtaaa tattgcggga tttcacatat attggggttg atcagctcgt tttctttggc
     1801 catcagacaa atttcatcta agatcaaact gttttctact gctttcatag gtgaatcccc
     1861 ccatgtgaac ggtccatgtc catagacaag tactccaggg acttcgtttg gatctaattt
     1921 tctttcctta aacgtctcga caatcacatt ccctgtatga acttcgtaag cttctcttac
     1981 ttcttctttc gttaattggc gtgtacaagg aaccttacca taaaaagcat cagcatgagt
     2041 cgtgccataa gctggcaaat cgcgtcctgc ttgcgcccac atgacggagt gcgtggaatg
     2101 agtatgagta atagcagtta tatcttcaaa agtttgatac aaaacaacat gtgtggggag
     2161 atctgaagat ggttttaagc tatcttcttc tattatattt cccgacaaat ctgttaccac
     2221 catttgatct gcttgcatgc attcatatct gacaccgctt ggcttaatga cgatgactcc
     2281 tagctcacgg tccacttcac tcacattgcc ccaagtcaat ttgactaatc cgtatcgcgg
     2341 caatgccaga tttgcttcaa ggacacgttg cttcattgct gcaatttttt cttcacaaga
     2401 catcatagcc agcctccttc aatttagaac ttaagtagtc ttttgcctgc tggatttctc
     2461 ttcgaaagtc ttggcttttt tcactccaca tttcaatcag aaatgttcca tcataatcta
     2521 gacgtttcaa atgtcttaat aatccaagaa aatcaacaca accgctacca aaaggaacat
     2581 cacgaaactg gcctgaatat tcttttgtta cagggtaagt atcttttaag tggatagcag
     2641 tgatataatc gatccctttc tcaagttctc gagccggatt attttccggc catgcggaca
     2701 aattgcctag gtctggatat acttgtagaa aaggtgaatg aatctgttct ttgatttcta
     2761 aaaattttga aatggagttc ataaatggat catccatgat ttccacggaa agaatgatgc
     2821 catatttaga agcttccttt acgctttctt ttattccttc gataaagtct tctctggaat
     2881 tcattgattt ctcttcataa taaacatcgt atccagctat ttggattact ttgacgctta
     2941 gattatgcgc caaatggatt gcttttttca ttagttgttt cgctgctttt ttcttttctg
     3001 gatcagcaga accaaacgga aatcgccgat gcgcacttaa acaaatcgaa tggatacgta
     3061 caccggagct gaacatctct tctctcagct cagctatctt ttcttcagac caatctaatc
     3121 gtgctaaccg ctcatccgtc tcatcaatcg acatctcgat aaaatcgaag tccatttctt
     3181 ttacaaggga aaaacgttct ttccatgaaa tatctttggg taacgctttt tcataaatcc
     3241 caatttgagc catttcctta cccccagata cgaatgatct catctttgaa gttttgtgcg
     3301 gccttcatcg gatcatttgc tgctgtaata ccacgaccag tgataaaggt atacacatcg
     3361 atcccttcaa ataagtgtaa tgtgtgtgga tttaatccac cagttacaga aacattaaag
     3421 cctagttcaa tcagtttttt gatcttcgat aaatcttttt caccccaagt ttcaccagat
     3481 aacagcgcat cacggctttg atggtagatt acctgccgga taccgatgtt atgccaatcc
     3541 atggcttgtt caaaagtcca attgccgtag agttctactt gcaattcacc tatttctttt
     3601 tgtgctgcct ccatagttgg aatcgttgca caacaaatga ctgtcatcca gtctgctcct
     3661 gcttttgcaa cattactcgc cactgttcct ccagcgtctg cacatttcgt atcagcgact
     3721 agttttttat ctgggaacat actgcgaata cagcgaatcg ctttttgtcc ttcctgtaag
     3781 caaagaattg tgcccacttc aataatatct actacatcac caactttcat aacatctcct
     3841 aatgcatgtt ctaagtcatt gtgatctaac gcaatttgca aattcggcct gctcatctta
     3901 gttccttcct ttacttgttt ttttggtacc actttgtttc agcaaatttt tcactgattt
     3961 ctttgactga catcacattt ttgataccga taactgtaac tccttttttc tctgcctgag
     4021 taaacatatt caaaaaattg actggcgtaa aaactacatc gtattggcca gctgaacttt
     4081 ttccctctga aatggcacaa tgatggattt tggtaattgg tacgtttagt tctttcattg
     4141 ctttttccac acttctcatc atcatcaagc ttgttcctga tccatttgca cacgatacta
     4201 aaattctcat cttaatccct ccattatgag tgttgtctaa tcagattttc ttttatactc
     4261 tctgcttttc tgcatatgtg tcatagtctt ctacaatcaa aaaataacca tcaggatttt
     4321 tccgatattg taactgcgga atagccaata aaccaatgac aactacggca attccagcat
     4381 aacctaggac tttcatgatt actgtaaaca atggccaagc tgttgcccag tcgaacatcc
     4441 cgatataacc accgtatgtt gacatcccaa tccatgtagc gaataatgct gaaccgccta
     4501 cttgtatgat tcctgaaaga aacgggaaca ggcaagcggc tttgaatcca cctcggttat
     4561 tggcataaac tgctataacg gcattatcaa agaacaacgg aatgaaaccg gctatgacga
     4621 tcgttggtga tttcaataaa atcagtaaac caatcatcaa aaactgtccc aaagcaccaa
     4681 acaagaaccc aatcgttacc gcatttggcg aaccaaagcc aaaagtagca gctacgtcaa
     4741 ttcctggaac agctcctggt aaaatcgtgt ttgagattcc ttggaaagat tgagttagtt
     4801 catcgacgaa tgtccgaaca cctaattgca agatcgccag atataccgca aaatttaaag
     4861 aagtcgtcat aatgtagaat aagaaactct gcccttcttg catgaattgc gcttgaatca
     4921 aataatcttt gcctagtaca atcagaatga tcccaaagaa aaatagcatg agtaacgaag
     4981 tagcaaccat attctcattg aaaatcgaca agaatcctgg taatttgata tcttcaattt
     5041 ttttgtcttg cttgattgat ctatttttct tttcatcccg ctttttcatc cactcagcta
     5101 attttgcaaa tataaagatt ccgaacattt gctgatgtgc cactgcaaat ccggcacctt
     5161 ctgtcaattc ctgcgtgatt cctactgtta agttagaagc tactgtccaa taacaaccta
     5221 aaatcagtcc cataaaaatc aatgcttgta tcctacctag atcaggaaag caaaacagta
     5281 aaatccaaaa agcggtagct gcttgttgaa cctgaacgtt tccggtagtg aaaacggaac
     5341 gcagtttcgt atatttctga aaacggacta ataagatatt taaaacaaat gcaatcagta
     5401 ataaaatcat cacatctcca aaggtacggc caaatgtctc cattaatcca gcatccacag
     5461 cattttgtcc aaaataagga tctgtaacca tggcatccaa attgaaccgt tcctttagtc
     5521 caaccaagat tggccgaaaa ttattgacca aaccaccaga gccaacagtc aaaataaagt
     5581 aaccgaccgt tgcctttaag aatccagcga tgcattcatg aagcgggcgt ttcagcaaaa
     5641 tatagcctaa taacacgata aaaccaatca ggtatgctgg ctgcgtcaag atatttgttg
     5701 caaaatacgt ccaaatgctt aacaaaaatt cccccatctt ttttctcctc tatcaattaa
     5761 ttatattctg ccatcacaac ttggtaatca tcgatggagt tcgtagagat gagacgctca
     5821 accaatccat ctgtcattaa taattcggat aatttttgga tattttctag atgttcttct
     5881 ggatcttttg ctgcgagtgt aaaaaacaaa ctagccgttt tctcctcatt ctccccttca
     5941 ctttcaaaac ggattggctg tttcaacttg gtaaatgaaa tagctgttcc aaaaacacca
     6001 tcactttttt ctgaagaatg cggcattgct acttgaggtg cgatcacaat ataaggaccg
     6061 tatttttcta cacaatggat gatctcctcc acatacgttt catcaataat ttccttatcg
     6121 atcaatacaa gacagctttc ggcgatagct tcacgccaat ccgtgatttc tttatctggg
     6181 taatgaatca attgatggtc aaaaaagtat ttcagcaaga aactcccctt ctttcttata
     6241 aaaacgacgg aaacggtgta tcattttcaa tcgagaagac atcttcaaat cctcgataaa
     6301 aattaaactc aagatcatct ttgtttgtcg gatagatgaa tttcccgcct acttgccaga
     6361 tataaggttt aaatccatac ttcaggcgat cctttttgaa tttccaaatt tcagtgatct
     6421 cttttggatc agccataaaa ttagaccaaa tatcgtagtg gacaggaatc actacttttg
     6481 cattcaatga ctccgccatg cgcagcatat caacagaagt aactttgtct gttatccctc
     6541 gtgggttttc accataggcc cctaaacaga catcgatttt gtgttcatta ccatgtttgg
     6601 caaataaatt ggagtaatgt gaatctcctg catgataaag attccctcct gatgtttcga
     6661 ataaatagtt tactgcaatt tgatccatct cctgaggcat ttttcctttt aatacctctt
     6721 ctggatcttc acaagtgacc aacgctgtcc gatcaaacgc ttctaaagct actacattga
     6781 tgtctttgat tttgactgca tcacctggct ttactgtaat cgttttttct tcaggaattc
     6841 cccatttttg ccacgtgcga accacttctt ttggcccaat gaatgttgct tcaggacaat
     6901 tttgatgaac tgctgcggct gtatggatat ctagatgatc ggaatggata tgtgtaacga
     6961 ttaaagcgtc tacatttttt atcgcaaaag gatcgattac gaaaggctga gtacgtaaat
     7021 taggctgcat attttgaacg ccactcatac gcatcatctg atggcctttt ttcatcatgc
     7081 cattcccatg actacgtttt cccgtcccac accatagatc acataaaata ttcgttcctt
     7141 catgactttt cagccaaatt cccgtacagc ccagccacca catagcaaaa gttccaggat
     7201 ccactacttc tgtttcgatt tcttcattca agtatgtgcc ccactcagga aatgtttcta
     7261 ctaaccactt ttcttttgtt acttcattga cagttttact catttgcttg ctccccccat
     7321 atcgttgttc caacttacaa gtaaatatta atgtgtatca gcatccatga aaaccctttt
     7381 atatgaccgt ttgtttttta tatgattttc tttcagtaat caatgattgt ttcagtataa
     7441 taaagacaga tatgaatgtt taaatgaaca actagtcaaa taaatccatg gatcaagatg
     7501 tccctcagga ggcaaaagtc atgaaaaact cacttgtcaa tattgaaaaa cgtcaaaaag
     7561 aaattttgga actgcttcag cagactgaac aactatcaac tttcgaatta gctgaatccc
     7621 ttgatgtatc tattagtacg atacgaagag atttaaattt attagaagaa aaaaacgaga
     7681 tcatacgcaa ttacggttat tgttcttata attacaaaaa ccagactgat tttgatcaat
     7741 ctggtcctga aaggattaaa caagcgattg ccagagaagc tagtaaatac attaacgatt
     7801 atgatacgct gtttatcaat tctagctcga ctgcgttgaa aacactggat tttcttcaat
     7861 ctaaccattt gacagtcatt acaaacaacg tgaaaatcaa ttactctccg cacaaagata
     7921 attgtagtta tattttaact ggtggagaga tgcgctttcc aaaagaagca ctagtgggcg
     7981 acatcgcatt aaatacgatt tcttcagtca atgcagacat ttgtatcatt ggctgtagcg
     8041 gagtcgatgt agtacatggg gtcacaacaa agatattaaa tgaatcaacg atcaacgaaa
     8101 tgatggtcaa caagacaatc aaatgtaaga ttttagtcgc tgatcatcga aaaatcggac
     8161 tgacatcaaa gttcaagatt gctgatattt cagtctttga ttatttgatc actgataaat
     8221 tttgttctga aaaagtatta gaggagatca gaaatacggg gataaaaacc attcaagtag
     8281 attcatttta agaaccagga cgtaaatatg taaataggat tatcaaaaaa atgaataaca
     8341 aatttatcga taaatgaaaa acacgctacg ctcaaattga taaaggaatc ccaagatgta
     8401 tccatccaat cgataccatc ataatctatt gcttctttta taaccgttat atgttgccta
     8461 aataggaatc aaacaatatc gaaaaaagga ggtatgacaa aagtcacacc tccttttttc
     8521 gaataaacgg tattcaaatc agaacactga tttcacaacc actttatttc aggtcgtttt
     8581 caatcacctt taccgcgtaa tcatttccgt tgaaacgcgc tatttttttt gcgtccatat
     8641 atctttctaa ataatcatct tctcctaatt gcttatggca agaagcaatt tcataaagca
     8701 agtattccaa tgcataagtc gatttatgtt tcttattata ctcaataccc ttctcacata
     8761 attggattgc tttatcataa tcctcgattt tacggtaata ggtggcgata tcataatata
     8821 caatgcagac catcagatta tcaaaatcag tctcactcaa tattttaagt gtacgctcca
     8881 cataaacttt cgcaaaatct aattctcctt ttgacaagta gatcattgcc acgtttgcag
     8941 ctgcttgtaa gtgatggata tctgtttcgg tcgtttgttc caacacttga ttaaaataaa
     9001 ataatgctgc atctggtttt ttcgcataaa gatgatcaag cagtccttga taaaataaaa
     9061 tttgatttaa aagatcagaa ttacttactt tttcctgatc gatcgtttgt aaaattttat
     9121 aagattcttg gtattttgat acagaattca atgattgaat ctcatttatt tttttcctga
     9181 ttttgtcttc ttctgtttct actaatatat cggagatctc gacattcagc tttttgcaaa
     9241 gcgcacttaa gatattgatg cctggcgaca tattcttgtt ttcgatattg ctgacagttg
     9301 cttgttcaca aatgccttct gctaattgta cttgtgttaa cccctttttc tttcggtatt
     9361 cttttagtaa tgctccatct actttaatca aaacaatttc cttcccttta aaaaattatt
     9421 tctcctttat atcatacaca aaaaaaagtt ctaaacaacc aaaaatgttt agaacagaat
     9481 aaaaatttta attttaaaat aatattcaaa ttaaacaact ggcgtatctg ctccttgatt
     9541 tctttttgtg ttatctgaat aattatcgtt tacagttata acacatagtg aaaattgtca
     9601 tggcgagaaa gtctaagaat atttttaaac ataactattt ctttcttacg tgtgtataat
     9661 gacgacagca cacctatcaa ttaatataat tattttattt ttttatgttc tcatgtttat
     9721 ttttaatgac acaacttctc gtatttatct ggcacaacat ataaatcgat caaaaaattg
     9781 ttgcgtgttt ttttgaaaat tggagtttca acttgattac aaaatttaaa tttagaagtt
     9841 gtgaaaacag cgagagacag tttaatattc aaaatataca taggctactc gaacgctgtg
     9901 ttttttagta tactagtaag aaacgaaggg atagactcat tccaataagg aggatttcat
     9961 gaagacaatt ctttttgctc ctgcagtatt caatttagct gagacaacac gaatgattga
    10021 ggttgccaaa gctatgaaag accgttatta ctgtgtattc tttggctttt ctaaaacttt
    10081 tgctcctttg atcacagaaa gtggctttga gtatcattta ctagcgccga tccttacgaa
    10141 aaaacaagaa gaacaaatca taaaatttga ccagttgcgt acacttaaaa acccttttac
    10201 caaagaaatg gttgcctctc gtatcactag tgaacagagt ctgattgcta agtttgagcc
    10261 tcgactgatt gtgacaggtt cgaatgtgac aattttttta tcggcccgca ataaaaagat
    10321 tcctttagta tatgttaaac cctatgcttt gagtgaacct ttttttcaat cagagcatgc
    10381 gctgatgccc cacgagttac gtttcttcgg ccctttaagc aatccccttt ggcactggac
    10441 aaaaaagcgt atagtaaata cccgatggat ccccaatgcc ttcaaacacg ctgcacaaaa
    10501 agaaatgctt cctttaccaa aaacaagttt acaaatgatg gatgctgatc taaatctcat
    10561 cacaacgcct aaactatttt tggaagaaga acagctgccg gaaaattatc gaatcgttgg
    10621 tccaattttt gctaagctca gtacttcctt gcctgaagaa gtgctaactt ttatacagcg
    10681 aaagcaacaa gaaagaaaac gtattatcta tttcgcaatg ggtagttcag gcaatccgcg
    10741 tatgttacgc aaaattttgt tcttcttaca aaaacaaccg gatctagcgg ttattgcacc
    10801 tattgactat ctgcttgatg acattcaatc tgactcagaa gatcttttaa taacagaata
    10861 tctgtctagt catcttttgc atgaattcat tgatttttct tttatccacg gcggggaagg
    10921 gaccgtccaa actgcctgtg aatccggcaa accgtttatc ggtgtgggga tgcaatttga
    10981 gcaaagctgt aatattgact attgtgtaaa atacggaaac gcaatcgccc tcacaaaacc
    11041 agtgactgaa agaaaactgc agattgctct gcgcgaagtt tcttcaccca agattcgtca
    11101 gcaggcacgc acgctgcaag ccgtttttcc aataaatggt ccacaacaag caattcaaga
    11161 aatcgaaacc ttcctgagca accacccaat atagtttcaa gtagaaaaag cttttttaat
    11221 agagactcat cagtaatttc gctattcgag acccagacag tgaaaataca aaaaaagtaa
    11281 atagtggatt gaaaagttag agttacttaa attacggtgt ctaaaaaaca caaaatcatc
    11341 cttaaaataa aagatctgac gctatccaaa tgagcatagg tagcgtctgc catttattct
    11401 tagtcaaatt ctttgacacc tttctctggt tggatcatct caacgtttct tcaaaagaaa
    11461 gaccataata attaggcaaa tacattttct taaaatgtgt catatagatc tagaagcatc
    11521 gctttgtaga gatttgtgcc gctagtcccc tcaacaatta ctaaatcaaa tgtaggattt
    11581 accactttat ctttgataat caacctccct cttctgttga gacaatgatc tcgcaatccg
    11641 atgcatactc ctatataaac tgccagcaat ccccacatat tgagtagatc atgtcagaat
    11701 gttctatgtc gtcagcaacg atacactaaa agtcacgttc accatgactg attgctattc
    11761 ccagcacaat tatttctata cacgtttcat gatttgaata aacactcaca tcatacatat
    11821 taccattcat acaccatact gcagccccta ctatatggtt gtaagctccc aaatctatat
    11881 ttgacttgat cactttggta gtagatctac taattctaaa tccattgctg ataaaatttc
    11941 cattttttcc tccttctttc tgccaaaaca gttaaaacaa taataatctt tatgtaaaaa
    12001 agggctgtga caaaagcctt gtcacagtcc catattccga ataaacggtg gtcaaaagct
    12061 tgcatctgcg gtaataagtt caaccaaacg aaaaataagc caacatttca caaaaattta
    12121 agaagcaatt ttcgtaaatt tcttcttatt tcttgaagct aaccacttct gttacaacca
    12181 cttttagaac atttaaagct tcgatgtgac aaaccatcta tgctgctcga tcataaaatt
    12241 gatagcaaaa attccacaaa gtacatatgt cccccatgaa aacaaaacat tcatatgcgg
    12301 tacaatgatc tttggaagaa tcacgatcaa aaatgatgcc agtgcccaaa tccatcgatt
    12361 gatttgaata tgatatgtag ctagcatatt caatataagg tgactagccg ttaataaaaa
    12421 gataaaaaca aaaaataaaa tcagccaata cattgtttcc caccttctaa aaaccaaact
    12481 tagacagtct ggacttcgtt ttctccacga ctttgttcat ctgacagcat ctttttatca
    12541 taagctttta caaatggata atagataata aatgctatca atgtgttgat catgatcaag
    12601 ataacaacac gccagtcatt tcctgctgaa agataaccgc cgattggagc tggtaatgtc
    12661 catgttggca aaacagtaaa tctattgacc atttctaatt tgactgcaaa ataactgata
    12721 atagtcaaaa ctaaaggaac taagttgaac gggatgaaca tgtaaggatt caacatcata
    12781 ggagctccaa aaattatggg ctcattgata ttgaagatac caggaataat agaaaaacga
    12841 ccaacctctt tcaagaattt tgatttacag aagaatataa acaaaacaga taccacgatc
    12901 gttgctcctg caccaccaat tgttaccgtc cattgataaa actgttcagg agcgatatag
    12961 ggtaattggg tggcagctgt accatctgcc aatgcctttg cattctcatc caacatgatc
    13021 agccacattg gacgaacaac agcccctaca atactcatgc catggatacc aaatgaccac
    13081 aacaaatgga tcaaaaacat tggtagtaaa acaccaagca aattattccc taaaatattg
    13141 gttaaaggct cgaataacga taataaggca gcgtttacat caaagcccgc gacgcttcga
    13201 atcagccaag taattgttaa aatgactgca cctggaatca atgcctcaaa actacgggca
    13261 acagcaggtg gcacttgttc tggcattttg atagtaatat ttcgattttt aaagaaacga
    13321 tatacttcca ctgcaaaaat catagataag atccccgcaa acatcccaga tgctcccaaa
    13381 gaactcatag gtaagaccca gccaagaggt gcctcttcag gagttaaaac gtttacagga
    13441 acttgtaaca taaagaacgt tcctaaagat aatataccac ctgtcacact atctaatcca
    13501 tatgatttag ctagatccga acccataaca aaagttgcat aaatagccat caatcccatc
    13561 gtcatcctaa agggtaaaac aatcgttgcc gaataagggg caataaattc attccatcca
    13621 ggaaacggta aattgataaa gaccataaaa aatgtcccaa tcaaaatcaa tgacaatgtt
    13681 gaaacaaccc cattacgaat tgctaataaa tgacgctgtg taccaatttt tgccattggt
    13741 gggacaagtt tctcttcgac ccatttcatc agcttttcca ctaaaaccac tccttttcaa
    13801 taaaatatga accattcatt gcatgacaac gcaaagaatg ttcataacta attatataat
    13861 taagaaattt tatttcaata tattctctta aataatcaaa tttattttta agaatcctga
    13921 aaataagttt tctaaatcat aggagcaaca aaaaaattcg ataattaaca aaaatcaaaa
    13981 tgattaaatc tagtgattga aacatatcat ttcaaaaaaa ttttgtaaat tcacccataa
    14041 atatcaccct atttaacttt tttcatcgta cactaaaatt caaaacaact atctttaatc
    14101 tttacttctt ggttttgttt taataaattt ccttcaaaaa tgcctggaga aactacaatg
    14161 atcaccgtat ctttttgtgc ttgctccaac ttcttcaaat ctataatagc taacagtgtc
    14221 ccttctttta cctcctggtt actttcaacc cgtatctgaa acggacttcc ttcgagttca
    14281 actgtatcta aacccatatg gatcagtatt tttctgccag attcactttc gatcgttatg
    14341 gcatgtcggg taggaaatat attatcgatt attcctttaa ctggcgcatg gatatatcca
    14401 tcatgattcg ttatagcgta tccaactcct atcatttttg aagaaaagac ctcgtctttt
    14461 actgctgtta atggaataat ttgaccacta gctacagctt ttagaatgtt tcttgtttta
    14521 aagaaatgca ctttttatca cctctacttt aatgctggcc aatatttttt gtttactttg
    14581 atcatttcat ctagtatttt ttttgcgact ctggcatttg gtacggtttg attcaatgta
    14641 aatgcttgta aagctttttg ataagaacct tcaaagtaag catttactag taacttctct
    14701 actgcaactt gtgcctccat caatccttta tgaaaatcac tgattggttt tcttagtgta
    14761 attggctcca caccagttgc accaacatat gccggtattt caacaactgc atctgaccgt
    14821 agattcggaa tcgccccttg attaggaacg attagcataa agcgacgacg atcatcattc
    14881 aacaaggaaa tagctatatc gacgatatat tgtccatgct ccccaaaatt aaagttcaat
    14941 acttcttcca caataccgcg gcgtatttta tcagccattt ctttggtatt tttctctcgt
    15001 ccatccatga ccatattagc acgtgtatac tctttgtcag tatgctcaac gaccatatca
    15061 ggatataagt aatactctaa gtaattattc gggatattac ttggaaaatt tttcgtgatg
    15121 actgacatca tttgaaaggt tttttgccaa gttttatctc ctatattaaa atcggcgact
    15181 tgcatttctt ttgttattag tttttcaata atctctggca taatttctcg ttgcaattct
    15241 ttatcataaa tcgatgtata ccagccaaag tggtttaaac cataatacgt aacgatccaa
    15301 ttcttacgat cataaccgta attcactgca atcgtttctt caattgaaat agtcatatca
    15361 caggcattaa tcatttttac attcggatat ttacgacgaa cagcttcaga aacgatcgac
    15421 tctggatttg tataattcaa aatccatgct ttgggggcat agtcttgtat atgatcgaca
    15481 atttccaata aacctttgat tgagcgcatc ccataagcaa atcctccgag tccacacgtt
    15541 tcttgtccta ctaatccatg tttaagtgga atcttttcgt ccttttctcg catctccaat
    15601 cctccaacac gaatttgtga gaaaacaaaa tcgcgtcctg taaaagcaag ctttggatca
    15661 tccgttgcac gaatgcgaat atttgaaaaa ccttttcttt tcagcataaa tttaacaatc
    15721 aagtacatat ccatatttct ttcttcatca atatcatata aacgtatttc agataatggc
    15781 aaccgttttt cattgttcaa aatggcttga acgattcctg gtgtatacgt actcccgcct
    15841 ccagctatag tgataatctg ttttttcatc atcatctttt cctttctatt cttctaataa
    15901 tttattgaat tctgccataa cataagtcac ttctaagccg atgataattt gataattttt
    15961 ttcagttggt ttaatgatcc cgcttatccc taattgcttg attcgctgtt cctcgaccat
    16021 ggtgggatcc actacctcta cccgtaggcg tgtattacaa ctatagacat ccaggatatt
    16081 ggcttttcct ccaaacgctt gtagcatttt tgttgccata tattcataat ttttacttgc
    16141 taaccctaac tctgtttctt ctaaggttac ttcattgcca aactctgcct tagcttcacg
    16201 tcctaatgtc tgaatgtttc tcttattgat caaataataa aaagtaacgt aatacaaggc
    16261 aaaaaagaaa attccgattg gaagaatcaa aatagcattg gtagcgattc gaaaattgat
    16321 gagataatca acaatacatg ctccgaatgt aaaaccaatt cgtatattga ataagtaaca
    16381 gacaatccct gctaaaccgg caaaaagtgc atggatcacg tacaacatag gagaaagaaa
    16441 catgaaacta aattcaacag gctcagtgat atttgcaata aatgaagttc ctgcaccgct
    16501 tcccatgatt cctttgacca tctctttatt ttctttataa gctgctttat agatagctag
    16561 acatatagct ggtataccaa acatcattac tacaaaaaaa actgataaaa acagtccagc
    16621 ctgaggatct ccgttgataa agcgtgtcat ctctcctctg aaaacttcct tgctaggaga
    16681 tgtatagctt cctaaatcgt aataaatata cgtattcaac acatggtgca gtccaaaggg
    16741 gatcagcaaa cgattcaaaa acataaatat ccccacacct aatgctccca tatcaacgag
    16801 cagttttgca aaattatcaa tcccaatttg gatgagcggc cagataaagc ccaaaaaaac
    16861 agctgcgatt gtttgtagaa tcatcaccat agtcaatggg aatttttcgc ccgcaaaata
    16921 agaaaaaact actggtaatt tttgttcttt aaagcgatta tacgtccatg ccgctactaa
    16981 accggaaata attccaccaa aaatccccat attcacttct gggtccataa tttctaagcc
    17041 ttttttcaag gtagcaatcg ctaaaaaacc agtaagtgca ggtattcctt tgtccttatt
    17101 tttgacaaaa ccgattgcaa ctcctatagc aaataagata tccaagtttc caaaaacggc
    17161 atttccagct gcaccaatta ctgggatgtt cagcatatcg tcagctgata aacgcatgat
    17221 caatcccgct aatggcatcg ctgcaactgg aagtagcatc gctcttccaa gcttctgcac
    17281 atttgattta acattcattt ttattcctcc tctattaaat atcctcatat gttactaact
    17341 caatcaaagg atcatttttc actttttgag caaatgctga atgaattaaa aattcgactt
    17401 ggtgggtacg aggatacaca aaacttgaac catttaacaa ttcctgatcc aaatacgctg
    17461 cgtgacacat gacttcgatc gttttatctt ctctcaatat catgagtaaa cttgccaaat
    17521 attcttccac actcgtattg atttgtcgtt ttttttcatc agtttctcct acgacatcga
    17581 aacaaggctc aaaataatcg acatgacgaa cttcatcttt tcgttcaaag ttgctccgaa
    17641 ccggcaaatc atattttttt gctaatgtaa caactacctc ctgattttca tccaaagtat
    17701 gagtatgatg atgactgtct aaatgagttg gtatgatccc cgcatgataa attttttgaa
    17761 tctgagcatt ccattcctga tacagttgat ctttgtcaat gttaaatgga tgctgataat
    17821 aagataagga tctgaactct ccgctttcga taagagtatc gacagttttg aggagtggtt
    17881 tgccacacgt caatgttaaa tggactccta cacctagcct aggcatttcc tttcttagtt
    17941 tcacagcatg ctcgaaaccc ggcatatttg ccatcaatgt agttgatgtc aaaattcctc
    18001 gctgataagc atccataatc ccataattca caccatggct atagccaaaa tcatccgaat
    18061 taaaaatcac ttttcccatt tcattctcct tcttttttct actaaaatag gcgcaaccaa
    18121 ataatcatag tccatttact atgtgtcatt tggttgcgcc tatagatagt tacgccctta
    18181 ttttaataga ttcttgctag atgaattgcc aaatagatga tttcattttc ttgaatggca
    18241 agttgaaatt gctgttcgat gatatcttta atctttagtg ctgtacaata cgctttgcta
    18301 tgtttaaatg tttcagtaaa aaaaccaata ttttctactg gcgtttcttc ctgataaatc
    18361 aagcgtttaa ccaggaattt gatatgaacc attaagcgat gataagtcag tgattcttta
    18421 tcataaacgt ttgaatagga tttttctaga tgggacaaaa tcgtggtcgt catttctact
    18481 atttttaagc tctttaaact attaggctct cctagctcag cattaatgat atgcatagtg
    18541 atgaatccta cttcatttga ccctaactcg gtttgatatc gatgattgat tcgctcgacc
    18601 acttctactg ctatatcata ttcatttgga taaaggaatc tcatttctgg caacataatt
    18661 gctgtgacat ctctatcttc tctttttcgt tgaatagcaa aataaatatg atctgtcaat
    18721 gtaatataga tatttgaatc taatggagag gagatcctag ctgttatcag ttcaatcact
    18781 tcttccgcaa aatccataaa ttcgattgga atctgcgaga ctatctcact gaatcgtttg
    18841 atcttttctt tagaatctaa tacaaataat ttgtcagcat cctcaacatc aaatggctta
    18901 ctcactttag cagaaaagcc aatccctttc cccatcgcaa ttttttctat tccatcgtca
    18961 tcgatcaata cagcattatg attcagcttt ttcatcacat acaccgttaa ttcacctcct
    19021 ctatatgata aaacaaaaca acttgcagac tccttcatac atatttttgt ctccaaacaa
    19081 tttttaaaga caaaaaacga cctaagaaag aaccctttct taggtcgtgc ctaattgaat
    19141 agtagcaccc tacataattt acaaaaatag tttaacacat aataaaagcg ttatcaatat
    19201 cttttttact cgttttatga taa
//
LOCUS       DAFBSV010000055        19102 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.056, whole genome shotgun sequence.
ACCESSION   DAFBSV010000055 DAFBSV010000000
VERSION     DAFBSV010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19102
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.056"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(21..251)
                     /locus_tag="LLB18_001806"
     CDS             complement(21..251)
                     /locus_tag="LLB18_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244808.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(687..1253)
                     /locus_tag="LLB18_001807"
     CDS             complement(687..1253)
                     /locus_tag="LLB18_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBK5244809.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1253..2209)
                     /locus_tag="LLB18_001808"
     CDS             complement(1253..2209)
                     /locus_tag="LLB18_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBK5244810.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2209..2865)
                     /locus_tag="LLB18_001809"
     CDS             complement(2209..2865)
                     /locus_tag="LLB18_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBK5244811.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3235..5253
                     /locus_tag="LLB18_001810"
     CDS             3235..5253
                     /locus_tag="LLB18_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBK5244812.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5323..5529
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5680..8094
                     /locus_tag="LLB18_001811"
     CDS             5680..8094
                     /locus_tag="LLB18_001811"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBK5244813.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8442..9995
                     /locus_tag="LLB18_001812"
     CDS             8442..9995
                     /locus_tag="LLB18_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBK5244814.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10376..12160)
                     /locus_tag="LLB18_001813"
     CDS             complement(10376..12160)
                     /locus_tag="LLB18_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5244815.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12175..13896)
                     /locus_tag="LLB18_001814"
     CDS             complement(12175..13896)
                     /locus_tag="LLB18_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5244816.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13996..14757
                     /locus_tag="LLB18_001815"
     CDS             13996..14757
                     /locus_tag="LLB18_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBK5244817.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            15724..15992
                     /locus_tag="LLB18_001816"
                     /pseudo
     CDS             15724..15992
                     /locus_tag="LLB18_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16664..>19102
                     /locus_tag="LLB18_001817"
     CDS             16664..>19102
                     /locus_tag="LLB18_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244818.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTGLTTGEDGKLAIDGLAPGAYQLVETQAPIGYELDATPIEFEIERSQTAVVELTKE
                     NRLTPGGVVLTKIDD"
BASE COUNT         6278 a         3390 c         3843 g         5591 t
ORIGIN      
        1 ctcattaaaa agcataacca ttactccgat ctgtttttaa aattagtttc tacctctaat
       61 atatatcgag tttttatttt gccttcagag aatactgttt ctttttttgc agttacaggt
      121 tgtttatttt cggaaaaagc taatatagct aagattgaaa catccatctg gaatttatct
      181 tttttactgc tttgatcata aaagtctgca tattcatcac tgatattttt tctaataaat
      241 tcttccatca taaaaatcac ctcaaaacga ttatacgaac ttacgttctt gttgtaaagc
      301 gatatttgag gggcaaaaaa ggggcataat ttgactgata ttaagttagc tattgatata
      361 tgaatgacat acaaaaatat aaaatctttt aaaaatgctt atatatcaat gtttttgcca
      421 ttcttttata tatctgttat atgtcaaaaa aatgtgttca atttcaattt gtatttgaat
      481 aaagaggttg tgaaaaagct gtcctgcatc aagtaataag aacagccaat caaaaacagc
      541 ttctcatgtt tttgatttgg ttggacttat taccgcagat ataagctttt gagcaccgtg
      601 aataaagagg ttatgaaatc aacgctctaa cctgagtatt agagaaaaaa acgcaaaaca
      661 tatcatttat gttttgcgtt ttttatttat ctttttttct caatacaata taaaataggc
      721 ggctggttct tttggttgat aaaccgataa ttcagcacat tatatgtttc ctgtggcagt
      781 ttggaacaaa aagaatcaac catatccagt tctttttctc caccttcatg accatagtag
      841 acgacaagga tcaatcgtcc gcgaggcaca agtcgtttca atatttcttc catagctgtg
      901 cgtgtagtct ctggcatagt gatgattgct ttatcacttt ttgggagata ccctagattg
      961 aaaatccctg ctttgagatt ttgttgttca gctatcactt ctcctaacgt ttcgtggcct
     1021 tgtagaaaca atgagacacg ttcttctaac tgacgctgtt ctagcctttc acgagtagca
     1081 tcgattgctt gttgctggat atcaaaacta tagacatgac cagtttttcc gatgtgttct
     1141 gctagaaaaa ccgtatcgtg gccattgccc atcgttgcat ctacgacgtg atcccctggt
     1201 tgcaagattt cttgcagtaa tgtatggctg aaatgcaaag cagtttgcaa catcagacgc
     1261 tcaccttttt ccgtacatca tattttcctt ggaagctatc tctgcgaaga agttcttcat
     1321 caattgcatt caagacttcc cattttttca agctccacat tggtccaatc aaggaatccc
     1381 acggcgcatc ccctgtcaaa cgatggatga tgatctcttt tggtatcatt tccagctggt
     1441 cgcaaatgac attgacatag tcaggacggc tcattaattg aaggcgacct tcatgatagt
     1501 cccgcaacat tctcgttttg cgcatcagat gcatcaaatg gagcttgatt ccttggatat
     1561 ctgaatctaa aatggtgcgt ctgacatttt ctttcatcat ttctaaactt tcgcctggta
     1621 atccgttgat caaatgcgta caaacacgga tattatgttt gcgtaattta gccacgccat
     1681 ctaaataagt ttgataatca tgtgctcggt tgatcagttt tgaagtttct tcaaaagttg
     1741 tttgcaatcc aagttctacc cataaataca tccgctcgtt cagttcagca aggtaatcaa
     1801 ctacttcatc tggcagacaa tccggtcgtg taccgactga taatcctacg acacctggta
     1861 aattgactac ttgctcaaat cgttctttga ttatttcaac tggcgcatgg gtgtttgtaa
     1921 aattttggaa ataaacgatg tattgttgga catgaggcca tttttgatgc atcatgtcga
     1981 tttctttctg gaattggatt ggaagagggt cttcaggtgc aacgatcatg tctcccgaac
     2041 cagatacact gcaaaaagta caaccgccat gggcaacagt cccatctcga ttcggacagt
     2101 caaatcctcc atcgatcggc accttgaaaa ttttcccgcc aaactcattt cgtaaagcgt
     2161 aattccaaga atgatatctt ttatttcctt ctgaataagg aaaagtcatt aaaagtcctt
     2221 ctttctgtaa gagttatcta tttgttttct tttttctcta tacactggat aagtcaggca
     2281 cagccaagaa agactgagta agtagccgcc gatgatatca gtaggaaaat gaacgcccag
     2341 ataaatgcgg cttatcccga cacttactat aataaacatc atcagcaatt gaagcaatgt
     2401 gcgtaaggtt cttttttgaa caaaagctgg aagcagaaat agtaaagaac cgtaaagaat
     2461 catactgcct gctgcatgtc cactagggaa actgtaactt gtttcaacta ctaagtgcgc
     2521 caatgaagga cgctctcgca tgaaaaatag tttgatcacc gggttgatga ttccagcaat
     2581 tacaataaat ccagaaacga accaaaatgt ttctgccctt tttttcttat accacatcca
     2641 taaagccgca caagcaaata aaatgatgac ggtaagagga ttaccgaatt tagtcataaa
     2701 gagttggtag ctgttcagat caggataaga agctctgaca atgcctgtaa accactgatc
     2761 gaaaccagaa agccacgaca gatggaactt tacgatccag cccaaaatga aaaacaggac
     2821 aagaaagaag ctaccagcca cctgaaatga tgttttatat ttcatacaat tcctcctttg
     2881 aagcaatgac ttattatagc atttttggtc cagcgaaaaa aacggtaaag agataaaacc
     2941 aatgtatgat tcctctttga ataaccaata ttcttataaa aaaaataact gtaatcggaa
     3001 agacattttt tggtaatgca aatgaaatgt tagggaaata aaatcagtgt ttttcgaaat
     3061 ccttttaaac aagaacgtag acgtaggaag aacttgaaaa tgaacagaag ttgttcatta
     3121 cggtaaatta caatatgatt acaaaaaaca acaaagctct taaataactt ttaataaata
     3181 ttaagagaag ttataattat taataataga taaattgaag ttggaggata gaagatggaa
     3241 aacattgcaa gaaaagaacg gagacgttta gaacagacca aacgttttcg aaaagcaaaa
     3301 cgaggggcag caatcgtggg aactgcgatg gtaggctgtt ctgtcgctgc cccattagta
     3361 cagccggttc ctgttcaagc ggatgaaaca cctgttcagt tcggcgcaag aatcaataca
     3421 gcggcattta tcacagaaat tgctacttat gctcaaccaa tcgctcaagc caacgatcta
     3481 tatgcatcag tgatgatcgc acaagcagtt gtagaaagcg gttggggcag tagtgcgtta
     3541 tctcaagcac cttattataa tctttttggg ataaaaggca gctatcaagg acaaaccgtc
     3601 tacatggata cgcttgaatt tttaaataat caatgggtaa ataaaaagga gcctttccga
     3661 caatatcctt cttttgctga atctttcaat gacaatgcct atgtacttag aaatacttca
     3721 tttggcaacg gttattacta tgccggtact tggaagagca acacgaaatc ctatacagat
     3781 gcgacagctt gtttgacagg gcgttatgcg actgatcctg gttacgcagg caaattaaat
     3841 aatatcatcg caacttacgg attgacccaa tatgatacac cagctagcgg aaacgcaggc
     3901 ggtggagcga ctacaggtgg caataatact ggaagtgcag gtagtactgg cggttcaagc
     3961 aattctggta atacaaactc aggttcagca acttcgacca cttatactgt ccaatctggt
     4021 gattctgttt ggggaatctc aaataaattc ggtatcacaa tggatcaatt gatccaatgg
     4081 aacaacatcc aaaacaattt catttatcca ggacaaaaac tgacaatcaa aggtagccag
     4141 gaaaatggct cttcgacgaa taattccggt aacaatacca actcttcagg aaatgctggt
     4201 acatcaaacg gaggacaaac aactggtgcg aaatacactg ttcaatctgg tgattctgtt
     4261 tggaagatct caaatgatca cggaattacg atggctcaat tgattgaatg gaacaatatc
     4321 aagaacaatt tcgtttatcc aggacaacag ctaatcgtat caaatggcgg ttcttctaat
     4381 gctggagcaa atactggctc aaatactggg aatacaagtg gctctagttc gtccagctca
     4441 agttcttcta atacagcttc aggaacgaaa tatacagtta aagccggaga ctctgtttgg
     4501 agcgtctcaa ataaatacgg aattacgatg gctcagctaa tccaatggaa caatatccaa
     4561 aataacttta tctacccagg acaacaactg actgtttcaa acagtggatc aacaaacagc
     4621 acgtcaggta atacaggttc gtcaaccaat acaaataaca gcagttcagt taatactggc
     4681 agcagttcgt ctcaaggcac ttataccgtg aaagcaggtg aatctgtttg gagcgtggca
     4741 aataaaaacg gcatcacgat ggatcagtta atcgaatgga ataatatcaa aaacaacttc
     4801 atttatccag gacagcaatt gatcgttaaa ggtggaactt cggcaaatac aaatacaggt
     4861 tcaactactt ctgcagcgaa accaaataca ccgaatacgt ctgctacgac aagtacatca
     4921 tccactggta atacgatgta taccgtgaaa gcgggcgagt cagtttggag cgtagcgaac
     4981 aaacatcata tcacgatgga tcagttaatc gaatggaata atatcaaaaa taatttcatc
     5041 tatccaggac agcaagtgat tgtgaagaaa ggttcatctc aatcaacaaa ccaacaatca
     5101 gttactggtt cgaaaaccta tactgtgaaa tctggagaat ctgtttggag tgttgctgac
     5161 agtcatggaa ttacaatggc tcaactaatc gaatggaaca atattaagaa caactttatt
     5221 tatccaggtc aaacgttgat tgtagctaaa taaaatagct gttcgaagaa ataacgattg
     5281 aattccacaa aaatatttgt tactataagg ctacttaaat atgacaacac ttgaaaagga
     5341 agtagtaaaa agactgaagt ttcagagagc gcatggctgg tgagaatgtg cacggatgct
     5401 tttgaactcg cctttgagtt gcccttgctg aatacccgag taagcaagcg gcggtgacgg
     5461 ccgttacaac gttcgaggcc ttttcactaa ggtaaaatta ggtggtaccg cgtagattac
     5521 gtcctataaa aagagcaatc tttttatagg atttttttat ttcttttgtg aagtttgaga
     5581 aaacaaagca aaaggaaata aaaataaaca gattctgccg gttttttcgt tatatttata
     5641 atagaaacaa gtgttttcaa tagaacagga ggacagcaaa tgagttacaa tcataaagaa
     5701 attgagaaaa aatggcaaaa atactgggca aaaacgaata ctttcaacac ccatgatgat
     5761 cctgaaaagc caaaatttta cgcactggat atgtttccct atccatccgg tcaagggcta
     5821 catgtagggc atcctgaagg ttatacggca acggatatcc tttcacgtgt gaaaagaagt
     5881 caaggataca acgtgctgca tccaatgggg tgggatgcat tcggtctgcc tgctgaacaa
     5941 tatgcgctag atacaggaaa cgatccagct gagtttaccc aaaaaaatat cgaaacattc
     6001 cgacgccaaa tcaattcttt aggatttagt tatgactgga atcgcgaagt gaatacaact
     6061 gatccggagt attataaatg gacacaatgg atctttacga agctttatga aaaaggtcta
     6121 gcttatgaag cagaagtagc ggtaaactgg gtacctgaat taggaacagt tatttcaaat
     6181 gaagaagtga tcgatgggaa aagtgaacgt ggtggctatg atgtagtcag aaaaccaatg
     6241 cgccaatgga tgctgaaaat cactgcttat gctgatcgct tattggatga tctagaatta
     6301 gttgattggc cagaaagcat taaagaaatg caaagaaatt ggatcggtcg ttcagtagga
     6361 gcaaatattg aatttaaagt ggctggtacg gataaatcct ataccgtatt tacgacacga
     6421 ccagatactc tattcggtgc aacttactcg gttcttgcac ctgaactaga tcttgttaga
     6481 gaaattacga cccctgaaca aaaagctgct gtagaagctt atatcgaaga gacagctaaa
     6541 aaatcagatc taaagagaac ggatcttgca aaagaaaaaa caggagtatt tactggtgct
     6601 tatgcaatca atccagttaa tggcaaggaa atcccaatct ggatcgccga ttatgtatta
     6661 tcttcatacg gcacaggagc catcatggct gttccagcac atgatgaacg tgactttgaa
     6721 ttcgctcaaa ctttcggact agaaattctt ccagttatcg aaggtggaga tgttgaaaaa
     6781 gctgcttaca cagaagatgg tacgcacatc aactctgaat ttctagacgg catgaacaaa
     6841 caagaagcaa tcgataaaat gaatgaatgg ctagaagaaa atggcgtagg gaaaaaagaa
     6901 gtcagctatc gcttacgtga ctggctattc tcccgtcaac gttactgggg tgaaccaatc
     6961 ccaatcatcc attgggagga cggaacagtc acagctgtcc cagaagaaga gctaccatta
     7021 cggttgccta agacaaaaaa catcaagcca agcggtactg gagaatctcc attagcaaat
     7081 atcgaggagt gggtcaatgt cgttgatcct gtaacaggta aaaaaggccg tcgcgaaacg
     7141 aatacaatgc cacaatgggc aggaagctca tggtattacc tgcgttatat cgaccctcat
     7201 aacaaaaaag aactagcaga ttatgaaaag ttgaagcgtt ggctaccagt tgacatctac
     7261 attggtggag cagaacatgc ggtacttcat ttactatatg cacgattctg gcataaattc
     7321 ttatacgata tcggtgttgt tcctacaaaa gaaccattcc aaaaactata caatcaagga
     7381 atgatcttag gcgaaaacaa cgaaaaaatg tcaaaatctc gtggtaatgt agtcaatcct
     7441 gatgatgtgg tcgaaactta cggtgcagat acactgcgca tgtacgaaat gttcatgggg
     7501 ccattagatg cttcgattgc ttggagcgaa aatggcttag aaggaagccg taaattcttg
     7561 gatcgtgtat ggcgtttgat cgttgatgag aacaataaaa tgcgtgaccg tatcactaca
     7621 ttgaatgatg gcaagcttga taaagtgtat catcaaacag tgaaaaaagt gacagaagac
     7681 tatgaaaatc ttcatttcaa tacagcaatc tcccaattga tggtctttat caatgaagcc
     7741 tataaagtgg acgctctgcc ttatgaatat atcgaaggat ttgttcaact actcgcaccg
     7801 attgctcctc acatgggtga agaactatgg gcaatccttg gaaatgatgg tggtatttct
     7861 tacgcaccat ggccaacata cgatgaagca gcacttgttg aagacgaagt agaagttgtt
     7921 ttccaagtaa acggtaaagt tcgtgcgaaa agcaatgttc cccgagactt aggaaaagat
     7981 gagctagaaa aagcagcatt agccaatgaa atagtgcaag aatatattga aggcaaaaca
     8041 gtcagaaaag ttattgcggt accaaacaag ttagtcaata tcgttgctaa ttaattggct
     8101 ctttgtcaat aaggactgat gagttgtgca aaatcaaatc tgggccagaa tgaacttcat
     8161 tctgtctcag attttttgtt atttcaaatt gattaattga ttgatcaaaa aggttttgat
     8221 tttcatgttc tcaaacacgt tcaatgtctt tttcttctga atggtcttgt aagagatctc
     8281 tgtaatcatc aaatttttgt ctattaatct tagtattttt tgatgtataa actacctgaa
     8341 attgagagta cataccaaat tcataaattt tttattagtg ggactagtga ttgtatggat
     8401 tttgacgcat aatgaatgaa gtatgagaaa aggagagaca aatggatcaa gaactattta
     8461 ttatcgaagt attatcagct aaacaaaaaa ttatcgagaa agcgaaaaaa agagcgaaaa
     8521 gaataatgtt caagctttta agcttagtat ttttctctgg tttgcttttt ttcggagctg
     8581 tatcgttcct atatcgccat atgagtgcag tagtccgttc agctgaaggg atgcaaaaat
     8641 taaataattt gtatcacttt tcgtggggag ttggcggaat aacaattgtt gtgcttattg
     8701 tttttcttct acttatttgg ctccgttacc atcaattgtc gcgtcatttc gatcaatggc
     8761 ttagtcaaag agcacaacag tttttacata ataaaccaac ttctcaagat gatgactatc
     8821 tttattttga gaagacttcg acgagtcaag cttttcggat acaaaaaagt gattgccagt
     8881 tattgctgag atcacttgat gatttaccta tctacttagg cgaaagcaaa tcaaaattcg
     8941 gaatgaacac attccatatt tttttactag aaaacgaacc cagatgggaa aaaagccagt
     9001 cttcgcctgg tggatacctg acaactaaga tgagtacatt agtcactggt tttttcctca
     9061 ttcttttagc tggaacaatc tattatggga gatacactca gccaaaaatg tcttctcata
     9121 taaatgctgc ttctcacatg acaatgaact caactaacga tacgcatata caaaagacaa
     9181 atgaagggtt gttagctgat cctaagcaaa aggtaaattt gacaacacaa aagataaatg
     9241 atctcaaact tgatacagag acgcactctc tctatatgac aacagatagt ggtgctaatt
     9301 gggtatttgt gccgattgat tcgcaatggt tgcgttttgg cgaatacacc ctgacaacgg
     9361 ggctgattcc tgaaggttat tggatggaca acacatatga tatttccgcc gatttctcat
     9421 ggtttatcta ttcttctggg gatgatgtac gtctgctgac ttcaagagat aatggtaaaa
     9481 catggcaaac gtctattatc acccaatcag ttcagccgat acgttatcga aaagcggtat
     9541 tttatggcaa cgatggtcta tttatctgta catcagccag tgggatgtct gcagaaactt
     9601 tgtacattta cactactatg gatggcggaa tcacttggat aaaaagtgga agtacaatga
     9661 tcaatcagcc agtacaaaat gtcagcttcg ttacaacttc tttaggtttt gtttcgacac
     9721 gtgaaagttt gttttataca aacaacggag gacgctcatt caaagaatca gttctgtcga
     9781 ttccggaaaa ctatcagaca ggggggatag atctttttca atcaccaaat gaagttactc
     9841 aaataagcgc gaatacgtta gagacaaaat tttatttgtt gaaaaaagga ccaatcgatg
     9901 cagggaaaat gtttgcctgc ctcttccgtt caactgataa cggggaaaca tggcaattcg
     9961 ttcagcaact atcgcaagta gaacaaggag attaaagaag agagattgtg agcctgacgt
    10021 tcagcaccga gtcacaagaa acaaattcaa aaaacagctt ctcatatttg ttgaatagtg
    10081 taactcgtga ttcggagttg acaagagcaa caagaagcga ttttgaagta tagcttctcg
    10141 tattttacaa gatcgtgtct tattgccgat aggttgtctc ttgaacaccg tttattcgta
    10201 aaaagggatt gtgacaagtc ttttgtcact acttaccgaa cgaaactgaa ggagctatcc
    10261 aaaaagtatc attagtatta ttctttgtgt ttctagtggc accactagta catttaaaaa
    10321 agctatcgat catggactaa tcatacatga tcgatagctt tttagataat gtttgttacg
    10381 ctatctgaaa ttgactatta taaagactgg cataaagcgt tggtgattgg agtagttcag
    10441 aatgtgttcc tttttcgacg atatcgccat tcttcattac aaggatcatg tctgcatttt
    10501 caatcgttga caaacggtgt gcaatcacaa aacttgtcct atcttttgtc acagcttcca
    10561 ttgcttgctg aatcaatgct tctgttcgtg tatctacgct agaagttgct tcatctaaaa
    10621 taacgacagg aggattcgct agaatgactc gagcaattgt caataattgt tgctgtcctt
    10681 gagataacgt gccgttttcg ctagaaatga tcgtatcata tccgtctggc agtgttcgaa
    10741 taaagtgatc acattgtgcg atttcagccg cttcgataat ttgttctctt gtggcatcca
    10801 ttttcccgta ggcgatatta tcagctaccg ttccttcaaa cagccaggta ttttgtaaaa
    10861 ccatcccaaa agaacgacgt agttctccac gtgaaagctt ggtaatatca agaccgtcga
    10921 attcgatctt tcctttattc agttcataaa aacgcatcag cagattgact aaagtcgttt
    10981 ttcctgcacc agttggacca acgatcgcta ccgtttgttt tggctttact gaaaaatcga
    11041 cttgattcat caatatttta tctgatgtgt aaccaaactg tacatttttg aaagctattt
    11101 ttcctttcgg ttgttctaaa agtcttgcat ctggaaggtc tggaatttca tctgtttcat
    11161 ctaatatctc aaatatccta tcgattgctg ccattgcgga ttggatcgag ttgatcacat
    11221 aagaagcggt agaaattggt tcagaaatct gattgatgta ctgaagataa gcttgtaaga
    11281 agccgatcgt cacaccacct gatagaacaa gcatagcacc gaataccgca cttatgatga
    11341 aggcgagttg attaatgaaa cgaatggccg gatagatagc acagttcata aattgagcac
    11401 gtttaaaagc gttgtattgc tttttattta cttcgtgtat agcagcttct gcatgagctt
    11461 gctgattgaa tgttttgacc actagattac cagctaagat ttcttccatt cgattattta
    11521 aaacacccag ttcatactga ttctgttcag aaatctgttt gtttttgttc gcaatcttag
    11581 ttgtaacaat tgaactgcca acgatcagca ataagacgag caaagtaagc ttgctttcga
    11641 tataaaacag catcagacca gcagcagcta ttgttacgac agaagtaaaa aattgattga
    11701 tacctgtcaa taacacttga gaaagttgat tgagaccggt agttgtccga ctaatgatgt
    11761 cacctacttg atgattgtca aaaaacgaca tcggtaatgt tttgaatttt tttgtgattt
    11821 cttttcgcac cctcaatgtg atcttttcgc ttaacgctgc cattgtccgt tcctgaataa
    11881 atgaagtgat gctgcttaag actgaacagc cgatcagcaa taagacaggg aacaacaatg
    11941 cttgtttgat atcactgaaa gaaagctgtc caatacctgt ttttcttatt tctgataaga
    12001 gatcatcgat cccgattccc atgatcaagg gcatggctac gactaatagg ttcccgaata
    12061 aactgcatag aaacaatccg taaaaatatt tatgttcagg tttgatcatt ttccaaaaac
    12121 gtatcaaagc acgcgtgttc aacgtttttt tcttttccat cgtatccctt ctttctatat
    12181 tccttgtgat tttgcaaact cctgataagt ttggcaatta gacagtagtt cttcatgagt
    12241 accttgtcca acgatttttc cttcatctaa aacaatgatg ttatctgctt gttggattgt
    12301 actgaggcgt tgagcaacaa tcacgagagt tttctccgac atgtgtttat gaagggctgc
    12361 tcttaatgct gcatctgttt tatagtctaa agcggagaaa ctatcatcga atacatagat
    12421 ctctgctggt ttgatcaacg ctcgagcaat acatatccgc tgtttctggc cccctgaata
    12481 attagaaccg ccttgagcaa caaagctgtc caatccgtca ggaagggtgt ccactagttc
    12541 ttctaattga gcgatcttga tcgctttaga caactcttct gttgaggcat attcatttcc
    12601 catctgcaag ttgcttaaaa ttgtcccgct gaataagaaa gccttctgag ggacataact
    12661 gatgtgggag cggatctgtt cttgagtcat ttgagtaaga ggaataccac caagggttac
    12721 ttttcctatc gtagggtcac taagtctcaa gagaagtttc gccaaactac tttttccaga
    12781 tccggtcccg ccaacgatcg ctgttgtttt tcctttaggt attgtgaaat caatatcttc
    12841 tagaactgga tcagagattt cagtatattt aaatgtgaca tgttcaaaag cagctgcatt
    12901 tgtctgatca aaggttggtt cagctactgt tttgatcgtc tcttcctcaa tttcgatctc
    12961 tgcttgcagt atttcttcta tccgtcgtaa tgaggcaaac gatttaggga taatgaccaa
    13021 taccatagct gcgatcatca agtaagcaag tgtcagcata gagtattcga ctacagcagt
    13081 cacgacaccg atttgtaatg ctccttctgc tacaagattt ccgccaaacc acaaaataga
    13141 agcataaacg attcccatga gcaaaaaagc aattggagtg acccaagcaa atattcggtt
    13201 cactttgatc atttgattag catagtcagc aaagctctta ttcgttcgct tttcttcata
    13261 tgattgatta tcaaaggcac ggatcatatt aatcccagta aagaattctc tcaatgtgat
    13321 ggtgatccga tccatttttg gctggatact caaagataaa ggtgcccctc gtttcatcag
    13381 tcgataaaca atccatacat aaaaaacaac agagatcaat gtaacccatg ttagtaatag
    13441 agaataacga aacatcatga gaatggtgaa aacgcaaata accggtgctg gtaagatcat
    13501 ttggcaaaat aaaacaatca tttgctggac attatcgaca tcattcgtca ttcttgtcaa
    13561 aagagatcca gaactaaaac gactgatatc cttcattgac agctgttgga atttacggaa
    13621 atatttctcc cgcgtttgga atccaaacct agcggaagcc aatgctgaaa agtaactaga
    13681 ggcaactgca gcgattgttc ctagaaacgc tacaagcagc atttcaactc caattttttt
    13741 tataactgag gcttcgccac ttgctatacc tgtgtcgatc agctttgcta ctaattttgg
    13801 tacacctaat gtaccggcga tttctaaaca gatcatcaca aaggtaagga gagcgagtcc
    13861 tttgtttttc tgtaagaatg tttttaagat agacatatta ttcctccttt tttcctgata
    13921 cttttcgatt ctataccttc aagtaacttg aaggtcaata gaaaaaagaa taaactgaaa
    13981 aagaggtgag aaaaaatgaa aaaaatgtat acgattggcc aagtatcgga actatttgat
    14041 ttgccaaaat caacgatccg ctattgggat gaacaaggat taatccgttc aagtagacaa
    14101 gaagagaatg attatcgatt gtttgatatc gatgatattt ttatgcttta tgatatcgtt
    14161 ttttatagaa aattagatat accgatcaaa cagatgaaga atttatatgg aaaaacattg
    14221 acggagttat atgagacact tgatgaaaca gaaagaagaa tccataaaga actggtggtg
    14281 atgaaacaaa aacaaaaaga gataagggag caaaaaaaac agttgaaatt gatgatcgat
    14341 acaaacgagg aagaatttcc tgtagaagag atcccttttg actgtatgat ctcaacggag
    14401 tttgaagata ttgtggaaat caaaaaattt ctacctaact attcaagctt tgggatgatg
    14461 agtatgccag cttccagttc acagacgatg tatggatttt ttatcgaccc tagtgaagta
    14521 catttattta ctcaagacgt gatttgggag aaaaaagata cggctgttta tcgtcgattc
    14581 ttattgaaat ccgagatgaa ccatgcggaa cgtaataata ttttagaaat cagagaaaga
    14641 atgtatgaaa aaggatggaa aacaggagaa gtgatcggcc agtatctatt gacgaatacg
    14701 gatgaaaaca atatcagaac tgaatattat catgcatgga tagaaatgaa aaaataggaa
    14761 atatgtgttt aagataactc gaaaatgatg gttgttttag ttataaagaa aaattttctg
    14821 gttcgattac gggtttaatg tgggggatta ttagtcgtgg atagatagaa ttttagtttt
    14881 ttagaggaaa tatgtcttta aaaatggaat ggttgcaatt cttagcgata tatacgatgt
    14941 aattgtcctc ttaaaaaagt atggaaaaat aattgtattg ggtgttatgt ataattcatg
    15001 gtgaactgag actaatgaga agaaaaattc atattgttat gagtgagatt gtatcagatg
    15061 agaatgataa attaaatagg tgcataaaag cattacactt aaaatacatt gttgcttaca
    15121 ttattacaat atgttaataa ggcaaaaata aatagatgga ttgaataaac atatttttta
    15181 atcaaatagt ccctactgtg actttcctca gctatcggtg atactaccga tagcattttt
    15241 ttgcttataa aataattata agtatttaga gatttttctt ctaacattct tcaaacaaga
    15301 aaaatcacaa aggttattgt tatttttata tattcttttt aagaatgatt gtttttttat
    15361 agaaatttta aaaaataaaa cacgttattg atggatagtt agtttgttat ttggtaatat
    15421 tatagaagtt gactggtagt gatttatttt tcgtcgtttt ataaaaatgt tattttttgg
    15481 aaaaattcac aaatatgtaa cgaatgtttt tctggaattt gctgtgttaa aaagcagtat
    15541 gactaatata aatactattg tcatttatgc aattttttat ggatagtaat tttagagggg
    15601 aatcaatgaa ggaagaatag aagggaaaaa tagttgcaaa tacgccagtt agcaaaaata
    15661 gcaatacatc ttcaagcttt aaaattcgag agaatcatct tggtagtgga atcaactaca
    15721 acaaaaggat taaaccaatt aatagataga attaccaatg gaaaaataga aaaggtagtt
    15781 attctataca aaagttgttt aattcgcttc ggttatgaac ttagtgaaac cctttgcaat
    15841 atatggtaca gaatatagaa attattgaca ttacagaaaa tgatgaagat ttaatacaga
    15901 ttgtcactat ttgtagatac cttttacaag gaaaccgagc caataaagct aagaagatga
    15961 ttaaggagtt gatggaagac gatacaagtt aagaaagtga aactacgccc aaataaagag
    16021 caaaaagagt aattggacgt ggaaaatgca agaaatgaac catcgattcg gtggacagtt
    16081 tattagtaat gacggtttga gaacatccat gacgagaatg aaggaacatc ctaaatgcgt
    16141 ttagttgaac caagtgccaa ataatatggc caaataagcg atcagttatc gatgaatccc
    16201 aagtattcta aactatatat tcattttgat gctaagcatt gatatatttt tttgggattg
    16261 atgaaggtta accaatacag ggactcactg atgaaattct agagtctgac cttggtatca
    16321 acgatttagt gattgtttct aatggaaaag tataaaagta tataagtaca ttaacaaaat
    16381 aactattagg gttacgctcc agcttgtgca aggcactggc aggaggaatc gtgaaatcat
    16441 aattatggtt aagccacacg gacaactaaa agtcatacaa agctatcgaa tcaatcaaca
    16501 gaagacaatc ggcaatcatt agctttgttt acagcttaca ttgcaacgct tgagttgaac
    16561 cgaaaatacg agggaggtaa cgcagccatt ttgagttggg gaatcttttt agaaaattat
    16621 cgggtacctt gttgtttagt caaaattata agggggagta atagtgagga acaaatttca
    16681 taaactgtta agtatgtttc tagttatgct tattgtgatc aatcaatttg ggaacataac
    16741 ggttctagct gagtctttag cagaacagcc agagcgttcg ctgacgatcg aagttgatca
    16801 agaggaggct gctttgggtg agcagttcca gttgcgagtc agaggaacac cagacctgct
    16861 aaatgcattg gtcattgata agagtgagga tttgattgaa ggggaagtga agcaactcaa
    16921 tgattacgaa cgtctgatta cttattcttc ccagcattca ggtaaatacg aattgaccgc
    16981 aagaagcggt gatattcaat caaatacggt ctcaatagaa atcagtgtac cagaagaaag
    17041 cacaagtgag tcttttaatg taccagaaga aagcacaagt gaatctttta atataccaga
    17101 agaaagctta agtgaatctt ttaatgaagc cagatcatct gagccatcta taacgcagga
    17161 atctcagatt gaaagacaag aggagctctt gaattatgac atcggcatct ctgctgagcg
    17221 ccccactttg ccgagcaggc atacacaaac gttaaaggga tacattcaag gaggcgctgg
    17281 cgatattctt gaagaatatg gggagatggt cgtacgagtt cctagagcat cgattggctt
    17341 aattgagttc attagagtgg aggtcgctga tgattcacct ttaaagccac tggcatttta
    17401 ccaagaaggc acagacgttg tttttccatt tacctttgat tatgaaggat taaatgaagc
    17461 cgctcagtcg tatacattca gtatcacgtt tgaagttgct ttctttcaat caggcggtac
    17521 tgagccaaat aatgactttc aagtgagtct tacttatgct gagcgagcag caaacacgga
    17581 attttcaatt acgcctattc cttcatcaag acccattttt tcgaaattat actatggctc
    17641 tagagaaatc gacagccaag gaaatcttgg gaatctgctg attgacgggc aagacgtgac
    17701 caacagtaat aaatttattt tgcaggtaaa ttatgaagga tcacgaaaag acggtgtagt
    17761 ggttaccgat gtactaccgc aaggaacaac tttggcaccg aatccgacta catggagttc
    17821 cactggaaat agagaaccta tttcaggtgg ggttcggatc gcagaagtaa cgaatccagg
    17881 tgaagcaaac gttagaactc attatgtttc cgaggaattt gtggacaaag tatcttttaa
    17941 taaggaaacg aatacacttg ttgtggactt tggtaatcta gcagagggtc aatcgtattt
    18001 tattgaatat gctcttgaag tgaccgatgt cgacttgttc aatgaaggaa gacaagagga
    18061 tgggttttct cggaatcgag cgagtatgac ctacaataat caggtaatga gccgagacta
    18121 ccgcttgaga atccctgaaa gtaatcttcc ggcaatctct ttaagaaaaa gtgtggacaa
    18181 aaatgttatc aatctcaatg aaaatgaact aacgtatact ctgcatgtct cgatgttttc
    18241 tggaacaaga aatacgcttg ttattgaaga tgttttggaa gaaggcatgg aatttgtgtc
    18301 atttctatca gatattccct ctttcattga tgccgaagtc aataatggaa tagttcgttt
    18361 cagtgcgaat aatacgattg gtggtccgac aagttttacc ctctctttta aggtcaatgt
    18421 agaggcgtat gcggtcggcg atcaaatttt aaactttgca acgcttgtga atagtgacaa
    18481 tcgattgaat acgagtactg taagaacaag gaaaatcgat gggcgtatta aagtaattaa
    18541 aactgatgag aatggccaaa ggctggcagg agcaaaattt gaaattttat caagcgattc
    18601 acaagtgata caagaaggta taacggcaga aaacggagaa tttttaagtg aaccgcttcc
    18661 tgtaggtagc tatcaagtcc gagaaacaga agcaccggaa gggtatcttt tagatgcgac
    18721 ggtacatgat gtttttataa atgaatactc catagaagaa gtgacgttaa ccattgaaaa
    18781 catccttgat acgggtggtg ttgaactaat taaacatgct gaaggcagtg gtgaagtcct
    18841 tcaaggagct gtttttgagt tacagaaccg agaaggagaa acgctacaaa ccggtttaac
    18901 tacaggagaa gatggaaaac tggcaattga cggtttagca ccaggagcat atcagctggt
    18961 agaaactcaa gcgccaatag ggtatgaatt agatgcgaca ccaatcgagt ttgagatcga
    19021 aagaagtcag acagcggtgg tagaattgac gaaagaaaac cgacttacac caggcggtgt
    19081 cgtgttgaca aagatcgatg ac
//
LOCUS       DAFBSV010000056        19066 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.057, whole genome shotgun sequence.
ACCESSION   DAFBSV010000056 DAFBSV010000000
VERSION     DAFBSV010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19066
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.057"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            154..384
                     /locus_tag="LLB18_001818"
     CDS             154..384
                     /locus_tag="LLB18_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HBK5244819.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRQMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            481..1782
                     /gene="murA"
                     /locus_tag="LLB18_001819"
     CDS             481..1782
                     /gene="murA"
                     /locus_tag="LLB18_001819"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBK5244820.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1795..1971
                     /locus_tag="LLB18_001820"
     CDS             1795..1971
                     /locus_tag="LLB18_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBK5244821.1"
                     /translation="MSNQRYILLTLIKILMVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2106..2402
                     /gene="yidD"
                     /locus_tag="LLB18_001821"
     CDS             2106..2402
                     /gene="yidD"
                     /locus_tag="LLB18_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBK5244822.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            2587..3054
                     /locus_tag="LLB18_001822"
     CDS             2587..3054
                     /locus_tag="LLB18_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5244823.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3139..4023
                     /locus_tag="LLB18_001823"
     CDS             3139..4023
                     /locus_tag="LLB18_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBK5244824.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4137..4373
                     /locus_tag="LLB18_001824"
     CDS             4137..4373
                     /locus_tag="LLB18_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HBK5244825.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4461..4541
                     /locus_tag="LLB18_001825"
     tRNA            4461..4541
                     /locus_tag="LLB18_001825"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4495..4497,aa:Tyr,seq:gta)
     gene            4548..4619
                     /locus_tag="LLB18_001826"
     tRNA            4548..4619
                     /locus_tag="LLB18_001826"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4580..4582,aa:Gln,seq:ttg)
     gene            4744..4914
                     /locus_tag="LLB18_001827"
     CDS             4744..4914
                     /locus_tag="LLB18_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244826.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVRVKSKRP
                     TNHTKKWMAKNR"
     gene            5134..5841
                     /locus_tag="LLB18_001828"
     CDS             5134..5841
                     /locus_tag="LLB18_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK5244827.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5900..6544)
                     /locus_tag="LLB18_001829"
     CDS             complement(5900..6544)
                     /locus_tag="LLB18_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBK5244828.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDEAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGIPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6670..6957
                     /locus_tag="LLB18_001830"
     CDS             6670..6957
                     /locus_tag="LLB18_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244829.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            7065..7385
                     /locus_tag="LLB18_001831"
     CDS             7065..7385
                     /locus_tag="LLB18_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5244830.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7466..8779
                     /locus_tag="LLB18_001832"
     CDS             7466..8779
                     /locus_tag="LLB18_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBK5244831.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLSNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKIL"
     gene            8776..9495
                     /locus_tag="LLB18_001833"
     CDS             8776..9495
                     /locus_tag="LLB18_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBK5244832.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVNSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQIAQPKIIRTISLAR"
     gene            9623..10174
                     /gene="raiA"
                     /locus_tag="LLB18_001834"
     CDS             9623..10174
                     /gene="raiA"
                     /locus_tag="LLB18_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBK5244833.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTANAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            complement(10323..11596)
                     /locus_tag="LLB18_001835"
                     /pseudo
     CDS             complement(10323..11596)
                     /locus_tag="LLB18_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            11886..14420
                     /gene="secA"
                     /locus_tag="LLB18_001836"
     CDS             11886..14420
                     /gene="secA"
                     /locus_tag="LLB18_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBK5244834.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            14546..15647
                     /gene="prfB"
                     /locus_tag="LLB18_001837"
     CDS             join(14546..14617,14619..15647)
                     /gene="prfB"
                     /locus_tag="LLB18_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBK5244835.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            15752..16438
                     /gene="ftsE"
                     /locus_tag="LLB18_001838"
     CDS             15752..16438
                     /gene="ftsE"
                     /locus_tag="LLB18_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HBK5244836.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            16422..17315
                     /locus_tag="LLB18_001839"
     CDS             16422..17315
                     /locus_tag="LLB18_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5244837.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            17467..18915
                     /gene="cls"
                     /locus_tag="LLB18_001840"
     CDS             17467..18915
                     /gene="cls"
                     /locus_tag="LLB18_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBK5244838.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEIAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYILQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLIYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
BASE COUNT         6304 a         3232 c         4123 g         5407 t
ORIGIN      
        1 cagtcccttt ttttgcatat ttttagcatt tatttcctaa aaaatgtaag gggattccta
       61 tatttttaag tatacttgtt tttcctttta tacattttat ggtattatca ttttattagt
      121 tattataaaa caatcgttag aaaggacgtc attatgcaag tatacggaat tgatgcggtg
      181 cttcgaatcg tgagtcattt ggcgtttatc tacttagcct tctggtcttt acgttcgtta
      241 cgcattgaaa cttttttcag acaaatgcat aatacgcaaa ttagaatggc aatcgtactt
      301 ttttcaattt ttttagggta cactgcaagt aattttttct tagaagttat cgctttatgc
      361 cgaaatcttt tcgttagcct gtaaatttta aaaaaaggta ctattttaaa agcaaggatg
      421 ttataataga aaagattttg agtaagtgta tgctcattgg aattttttgg agggaacaac
      481 atggaagaga tcatcgtaag aggtggcaat caattaaatg gaacagtaag aattgaagga
      541 gctaaaaatg ctgttttgcc tattttagct gctagtttgt tagcagaaga aggtattacg
      601 acattagaca acgttccgat tctttctgat gtcttcacta tgaatcaagt gattcgtcac
      661 ttaaacgtag atgtagattt tgatgaacaa aagaatcaag taacaatcga cgcttcaaga
      721 caattagaaa tcgaagcgcc ttatgagtat gttagtcaaa tgcgtgcttc aatcgttgtg
      781 atgggtccgc tacttgccag aaatggacat gcaaaagtag ctatgcctgg tggatgtgcg
      841 attggtaaac gaccaatcga tttgcattta aaaggatttc aagctttagg agcaaaaatt
      901 attcaaaaaa acggctatat cgaagcaatt gcggatgaat tgatcggtaa cacgatttat
      961 ttagatttcc ctagtgtagg tgctactcaa aatatcatga tggctgccgt aaaagcaaaa
     1021 ggaacaacca tcattgaaaa cgtagctcgc gaaccagaaa tcgttgattt agcaaacatt
     1081 ttgaataaaa tgggcgctca agtctatgga gctggtactg aaacaatgcg tattgaaggc
     1141 gtggatcatt tacatgcagt caaccactca atcgtacaag atcgtatcga agcaggtacc
     1201 tttatggttg ctgctgcaat gacacaaggc aatgtgctga ttgcagatgc tatctctgaa
     1261 cataaccgcc cattgatttc taaattgatc gaaatgggtg cagaaatcat tgaagaagaa
     1321 ggcggagtcc gtgtcatcgg accaaaacat atcttaccta cagatgtaaa aacgatgcct
     1381 catcctggtt tccctacaga tatgcaagct caaatgacag ctatccaatt agttgcagaa
     1441 ggtacaagtg tagtgactga aacagtgttt gaaaatcgtt tccaacattt agaagagatg
     1501 cgccgtatga acgctcatgt caaaatcgac ggaaatgtag caatcatgga tggaaaccat
     1561 gaattgcaag gtgcagaagt atatgcaaca gacttgcggg cagcagcagc attagtttta
     1621 gctggcttga aagcaaatgg aatcacacgt gtgcgtaact tgaattatct agaccgtgga
     1681 tattataatt tccatatcaa actacagcaa ttaggtgcag acgttgaacg tgtagacatg
     1741 gatcaaactt ctgctgaaaa aacagcacaa acgattgctt aaggaagtgg ctgaatgagt
     1801 aaccaacgat atatcttatt aactttgata aagattttaa tggtgatctt attgcttatc
     1861 cttctttttg tggccggaac gatgatcgga tatggtgtca tcggtggcgg caatccattt
     1921 aaagtatttc agccaagttt gtggattcat attcgagact tttttcattg ataaataaga
     1981 atcacagtgg ttctagtcga tatgaagtga gccatgaagc agaacatgat aaaagaaaac
     2041 agaagggaac gttgacgtta gtcgcgatcc ctttttttag taaaagaaaa gaaggaatct
     2101 aattgatgaa gaagatattg atttatttag ttagaggata tcagcgcttt atttcgcctg
     2161 catttccacc tagctgccgt tattacccaa cctgttccaa ttatatgata aaagcaattc
     2221 aaacccatgg cgcgctaaaa gggacggtaa tggggactgc acggatctta cgctgtcatc
     2281 cttttgtcaa aggcggtatc gattatgtac cattgacatt ccgattaacg cgaaataaga
     2341 aagataaaaa agaaccagat tataaaaagg ttgtgaaaaa tacgggtagc actgagcgat
     2401 aaagaaacaa tttggaaaat agcttcttat attttgcaaa attgtgagtt attgccgaag
     2461 tgttggattt tgaacaccgt caaaaaaaag gttgtgaaaa atacggctag cactgagcga
     2521 taaagaaaaa gaggaaattt attgtcaaag taacaactcc gcaactactt atatggggga
     2581 caaaaaatga tcgaagaact aaacaagaaa gatttaccat ggtccttgtt attagatgca
     2641 gatcctgata aagaaaaagt tcaagtatat gtttccagag ggagtggctg gatatggaaa
     2701 gaaaaagaaa aaacaatagg tgtactgatc tatgtggcaa gggaaaaaga atacgaaatc
     2761 gtcaatgtag cagtaacccc aacgtatcaa ggaaagggga ttggcggaaa attacttgag
     2821 acagcttttc agaagctttc acaactcgct tccagtcaaa ctcagatcat catacgaacc
     2881 ggcagtacta gcagtgcggc gttacatctc tatcaaaaaa tgggctatgt ggagattggt
     2941 cgagtcaaag actattttat ccatcattac tctgagccca tttttgaaaa tggagatcaa
     3001 ttaagggatc aagtgatttt agcaattcac ttacctaaaa atagctttaa ctaataaaat
     3061 ttcaattcaa gaaaatgctt tcaaatgcta aatagataca ttacaatagc tttagcaaac
     3121 aaaaaggaga atatttttat gggaatatta gtttttgatt ttggtggatc ggctgtcaaa
     3181 tatggttgtt gggatggcaa agagattaaa ggtaagggac aatttgcaac gcctgaatct
     3241 tgggaagaaa tgaaagcgca attatttcaa gtttataaaa aaatactcgt ttcttttgaa
     3301 gtcgaaggaa ttggaatcag ctctcctgga gtagtgaata atgagaaaca ggtgattgag
     3361 ggaatcagtg cgattcctta tattcatgga tttaatattt tccgagattt ggaaactctg
     3421 tttcaacttc cagtaacgat tgaaaatgac gccaactgtg ccggaatggc tgaattttat
     3481 gaaggtgctg cccgcgatta tcaagatgtt gcttttgttg tggcaggaac tgggattggc
     3541 ggggcgttgt tcacgaaagg acaaatcaat aaaggggcac atctttacgg tggagaattt
     3601 gggttgatgt tcttaaatgg cgataagaca ttcagtaaac ttggtacagc ggtacagatg
     3661 gcttggcgtt attgtgaacg caaaggtctc gataaaaatg cttataccgg aaaagatgtc
     3721 tttgaattag cagaaactgg agatgcaata gcaaaagaag aagttgagag tttttatacg
     3781 tatcttacaa agggattatt cagtattcaa ttttcgtttg atccagaagt gatcgtatta
     3841 ggcggcgggg tttctgcaaa agaagggctc attgatgaga tcaaaagccg aatgaagaag
     3901 ctgacagaac aattcgatct gcatgatttc gaaccgcaga ttttattatg tgaatacaga
     3961 aacgatgcta atcttgtagg tgcagcagca aactatctcg ctgtacgtca aggggagaat
     4021 taagagcttt agagaaggtg cagcttgcat aaaagaagtg aatgaaatga ataggagatt
     4081 tttacctaag gaatgtttta tttgctgcag tatgataaaa tatctgagag gtgaaaatga
     4141 tgtcaaaaaa aaataaagat attgaagtgc gtatagaaga agtgaaaaaa gatatcaaag
     4201 gtaagaatta tgaagtcact cagttattta tagggaaaaa aatgattggt gagatcttag
     4261 cctatggacc aaaagaatat gaaattttct ttggtgaaga agattttgga aaagaaaaaa
     4321 gtcttgaaaa tgcgatagaa acagtgattc gacactggaa tctgcacgaa taaaaaaata
     4381 tcaaaaaaac tttcaataaa gggttgcaaa aatctggaaa attaggtatt ataactaagt
     4441 caggttgata caaacctttc ggaggagtag cgaagtggct aaacgcgacg gactgtaaat
     4501 ccgttcctta gggttcagtg gttcgaatcc actctcctcc atttcattgg ggtatagcca
     4561 agcggtaagg caagggactt tgactccctc atgcgttggt tcgaatccag ctaccccagt
     4621 ataccacaat cgtaagctct cgttagttcg agagctcttt tttttgcttt gctaccttgt
     4681 tccttgaaga ttctgctgat ttaagataga gttaagttaa ctacaagaat tggagggatc
     4741 cacatgaaat ggaaagaaaa agtagacgaa gcagctgaaa agttatatga tttggtcaaa
     4801 tcagaaaaat acaatattga agtgaatatt ccgaaaaaag gcggaaaagc ggtccgggta
     4861 aaatcaaaac gcccaacgaa tcatacaaaa aaatggatgg ctaaaaaccg ctaataataa
     4921 caaaagatcc ataagtcggc attttcatcg attttagggt cttttgttat tttctaggtt
     4981 ggacatatct aaaaaattgt ttctgacaat aggagtagga agaacgatgt gtgtctaaat
     5041 cctctgttga tggatagaaa cctttatctt tttcagttgt gaatcaggta tataccagtt
     5101 ataatagaag aaacgaaagg acgggtgtac gttatgtcga atcaattacc tgtatatata
     5161 cagattcatg accaattaaa aaatgaaatc gaacaaggta tatggaaagt cggagaccgt
     5221 cttccttcag aaagagaatt agcagtgaaa ttcaatgtca gccgtatgac gttgagacaa
     5281 gcaattcaaa acttggcaga tgaaggaatc ttagaaagaa agatcggttc gggtacatat
     5341 gttgcacgag aaaaagtaca agaaaaaatg tctggtgcaa caagttttac agaaattatg
     5401 gaatcacaaa atcgagtacc gtctagtcgg acaatctctt atttcttgac ttcgccaagc
     5461 tcaagtgaaa tggaaaaact aaacttgagt aaagatgaca cgatcttgcg aatggaacgt
     5521 attcgtttcg cagatgatgt ccctatttgt tttgaagttg ccagtgtgcc acaaaagctg
     5581 atcgatggct acagcaaagc agagattact gaatcgttgt atcgcacgct agaagaaaaa
     5641 ggcgggaaaa agatcggtcc agcgaatcaa acgattactg ctgtgttggc ttctgagaaa
     5701 attgctgact atttagaggt aaaacgagga gatgcagttc ttcgtttgcg ccagatttct
     5761 tattttgaag acggtacgcc gtttgagtat gtgcgtacgc aatacgtagg aaatcgtttt
     5821 gagttttatt tggaaaaata aaaaacaggt gatccctgat tccgtattag aaataaaaga
     5881 gaatcagaat cacctgtttt tatatatgat cagttaccag ttgctcgtga taagaaacag
     5941 gaccctcttc aaattggact tgtccgttca gcagctcaat gatggattct ttaaagtggt
     6001 cagcactttt ttcatctaca gcacagatga cgctaacttg atcagtatat tggatttctt
     6061 ttataaaaaa atgttggagt tcaagataat tctgtaattt tcctagttgc ggatacgtga
     6121 tcatcacaga gatctcctgt tgcaaggtac cttctacgat tccaatgtca gacaatgctt
     6181 gagagaccgc atgagtgtat gctcgtatta atccgcctgt gccgagtttc gttcctccaa
     6241 aatatcgagt gactactgca gctacattga tcagttgatt ttttttgagg acttccaaca
     6301 tcggtatgcc cgccgttcca cttggttctc catcatcgct gcttcgctgg atttcatttt
     6361 tttctccaat gatgaaggcg ctgcagttat ggttcgcttt ccaatgttct ttttttattt
     6421 cttgaatgaa actttttgct tcgtcctctg attctattcg tctaagagaa cagataaagc
     6481 gtgatttttt gatctcgatc tcactttgtc cattttcttt tattgtacga tagcgctcga
     6541 tcatcttgtc acctcttttt tcattttctt tattcagtat aaataaagtt ctaggttgtt
     6601 tcaacactgt aacggttgcg caattgctgt agtatgcgat aataaagaca aaggcaggtg
     6661 gatctgggga tgcaggaacg aatgaaaaag tacgatgcaa ttacgcatta tttgaagaac
     6721 aatggcggct ctcaagtaac gttgaccttt acccaatttg acgaactgct gtttcccagt
     6781 aacggacttc ccaaaacagc aagggaaagt acagattggt gggcaaatga ttataaacac
     6841 cctgaaaaag gtgcctatgg ctggataaat gcaggctatg aagtagttgt catcaatttg
     6901 gacaaagaat atgtcgtgtt caataaatta gtgaaatcta gttggctatt tgattaaata
     6961 aaccgcgttt agaaaacgtt gacaaatttc tttcttttta tataatagag taacagacgc
     7021 gaagaaaacg tttgcgtagt ttgttttaaa aaggagagaa aagtatggct aaaaaaacaa
     7081 tcatgcttgt atgttcggct ggtatgagca caagtttact agtaacaaaa atgcaaaaag
     7141 ctgctgaagc aaaaggaatc gactctgata ttttcgctgt gtccgcttct gacgcagata
     7201 acaatcttgc aaataaagac gtggatgtgt tgttattagg cccacaagtt cgctttatga
     7261 aagctgattt tgagaaacgt ctggaaccaa aaggcattcc tttagatgtc atcaatatgg
     7321 ctgattatgg tatgatgaat ggcgaaaaag tgttagatca agcaatcacg ctcataggtg
     7381 aataaataga acagtataac tatcgaacaa gcgatccaaa aaatagatcg cttgtttttt
     7441 cgtatatttt tttagggcga ataatatgaa tcatttttgg ggtagaaggc ttctgacgag
     7501 agatattaaa gcaatagact gtgaggaggt aaatttacca aattatgaga agatcgcagc
     7561 agtggaacgt ttgagcaact ggattctttg tcatcgctgt ggaatgagaa cgtccgtcat
     7621 tgatggacag cttgcagatt acggttattt ttgtacacat tgtctatatt tagggcgatg
     7681 cgacactcaa caagatttat atttgtttga tcagcctgaa gcaaaacctc gagaagtcgt
     7741 ctttttttgg acaggacagc ttactgaaaa acaaacggaa atctcaaaga gaatactttg
     7801 ccattcagaa aaaagacatc atcttatttg ggctgtaaca ggtgcaggga aaacagagat
     7861 gctttatcct attttagtgg aaactttaaa agctggagga agagtagcga tttgtacacc
     7921 gcgagtcgat gtttgtaatg aattgttttt acgctatcgt tatgtttttc cagaagaaaa
     7981 aatcacgttg ctccatggga atacagcaac ggcttatacc tttacttctt ttgttatctg
     8041 tacgattcat cagctatacc gtttttatcg gtcctttgat ttaatagtga tcgatgagat
     8101 cgatgcgttt ccttataacg gggatgcagg attagctcat gctgtgcaaa cagcgattaa
     8161 accagacgga cgattcatct acttaagtgc cacacctgat aaaaagttac taaaggagat
     8221 caagcagacg tttgacatcc acaaacttgc tttacgcttt catcggcgtt tgcttcctga
     8281 acccgtcttg gttttcatga ataattggcg acaaaaatgc aagaacaaga agaagataaa
     8341 atctttggtg cggatcattc atcaattaat taaagaaaac catatccttt tattttgtcc
     8401 aagtatcacg atgatgcatc gtttgaaagc cacacttcaa gaggctcttc cgagatatga
     8461 gatcacagat gtttcttcaa gagacaatca gcgggcggaa aaagtccaga aaatgcgaga
     8521 agcaaaatat gacatactgt taaccacgat gatccttgaa cgtggagtca catttgaaag
     8581 aatatccgtt atcgttttag gagcggatca tccggttttt actaaatctt ctttggtaca
     8641 aatcgcagga agagccgatc gtaaagggcc ttatacgaac agtcaagtat attttttcta
     8701 tgaagaaaaa actgcagcta ttcgaaaagc ttgtcaggaa atcaaagaaa tgaatgaaga
     8761 agggaagaag atactgtgag gtgcagttgc tgcagtaaag atatcgtcca aaatttaaca
     8821 ttcagcgaga ttattggtgt ttcgaaatac agattacctc agacttgttc agtttgtcgc
     8881 gcacaatttc atttattgga aacaagaggc tgttctggct gtcaaaaacc aatccatttc
     8941 aatctagaga gtacgaaaaa gaaagtaaat tctatccccg tttactgcag tgactgtcaa
     9001 gaatggaaga agaaatatcc gacctatgat tttcagcacc gtgccttttt tgtgtacgat
     9061 gaaaatatga aggcctggct caatcaatac aagtttatgg gagatatccg actagcaggc
     9121 acctttgcat ataaatggac gcagataaaa aaagaatacc cgacatacat ctattgtcca
     9181 atacctttat ctgaaaaaag gcgaacagaa agaggattca atcaagtaag cgagatgttg
     9241 aaagcagcaa gaattccttt tcagatgcta ctcaaaagag agaagcatct gctggctcaa
     9301 gcaaaaaaca cgcgaaagga aagattggag atgcctcaac cttttgaact tgcagtcacc
     9361 ttttctaaga tacaaaataa aaaaatattg attattgatg atgtctatac aacaggacag
     9421 actcttttcc acgcagcaga ttgtttgcag atcgcacagc cgaaaatcat ccgaactatt
     9481 tctttggcga gatgaattag atgtggaaat ttgatagcga tttaatttgc aaataaccta
     9541 gagttcgata taatagaatt aagaagaggg aaagagtggt ccttctcctt cttgattgtg
     9601 gtagacgaaa ggggtaattt ttatgtttag atataatgta cgcggcgaaa atatcgaagt
     9661 aactgaagcg attcgcgact acgttgagaa aaaagtaggc aaactagaac gctatttcag
     9721 tgacgcaccc gatgcaacgg cgcatgtgaa cttaaaagtt tatacagaaa aaacagcaaa
     9781 agtggaagta acgatcccat taccttatct tgtattacgt gccgaagaaa cttctccaga
     9841 tttatacgca agtatcgatt tggttgttga caaattggaa cgccaaatcc gcaaattcaa
     9901 aacaaaaatt aatcgtaaat cccgtgaaac gggcatgaat actgcaaatg ctgctgcttt
     9961 attcaatgaa gaggacgaaa acgaaaatga ttctgaatta gatatcgtac gtacgaaacg
    10021 cctttcattg aaaccaatgg atagtgaaga agcagtcttg caaatgaaca tgctgggaca
    10081 taacttcttt atttttgaag atgcagaaac aaatggtaca agtatcgttt accgccgtaa
    10141 agatggaaaa tacggactga ttgaaacaga ctgatcagcc ttacttaaat aacaacgaaa
    10201 acttgcagca gctactgaca gctgccgcaa gtttttttgg ctctttgtca aataggactg
    10261 atagagtgat ataagaacat ctaaggtaga attgattttc tgctttagat gtttttttat
    10321 gtttaataag tgatcagatg attgattaag aaaattctgg ttctcatcct aacccgtaag
    10381 ctattcgttt caatgctttg atgtgggtat gcagattttc tattttgcca tttgagtaag
    10441 gcaactctaa ggctaaacga atgccggatt catagtttat aaacgctttt tttatatgat
    10501 gcagttctct tggaaccgac ttgggcattg tttttacaag ctgaaagaag atgtccgctt
    10561 ctttgtcata aaaagcttga agaatttctt gatagtaagc ataagctatt cgtagttcat
    10621 cagaagtaga aagtagacgt tctacgactt cactttcggt taaataggcc caaccaaaat
    10681 tacgccattt tgtccattta tcataaacaa gcgtgtcctg tcgtttgatc agaagtcgag
    10741 ataaagcctt cacttgtcga tagtgtttgg cttgtattgg atcgtttcgg tcgaagcttt
    10801 tcatgactca tagtcaaata tccttaaaac tgcgaatgag gtgcttgacg atgtgaaagc
    10861 gatccacaac gagtttggca tgaggaaagc actcttttat cagcaaagca taagaggcgt
    10921 tcatatctgt tacgagtatt tttacgttta aacgtgcacg tcgttcaaat tgcataaaat
    10981 aagaaatgag atctttcttc ttacgtgaag gaagaatatc cagtaatttc ccagtatcgc
    11041 catccataca agaaaaagaa tagggaccga cttgattttt caatgaacga aattcatcta
    11101 ccaatgaaca gcgaggcaac caatttattt tcacgtttgt catggggagc agagaagcga
    11161 gtgttcgcga aacggttgac caagaaacgc cgcaatgttt agaaatcgtc gtcattgctt
    11221 gtttttcagt caattcctcc aatattttat aatgtacttg tttggcgata aaacagtttt
    11281 tttcaacaat gtaggtattc gccgtaaaat aggtgtgaca gccacgacag aggtaccgtt
    11341 gctttgccaa agcaagataa gtccgttgat tcgcacactt attgagaagg accagcgatt
    11401 ttttctttcc gttcttaacg atcagcccat gttgattcac ctgtttacac tgaggacagg
    11461 gctgaatcgt tttaatgagc gtggcagaaa caacgatact gttgattgaa tgtatttttt
    11521 tcttctcgac atgagtgatt tgaatgtttc catctttgat tcctagtaat agtttgataa
    11581 gatgaagatc aggcatacag aacgctcctt tgattgtgtt gtggtgattc aattctaacg
    11641 gagcttctgt atgttttgtt tttttatgct caaaaggact gatagaatga tttactatca
    11701 gtcctagaaa ttatagcgcc gtttttttga gtttcctcct cttttagatg aaatatgaat
    11761 aaattatgaa gttcttactt taatacgctt aagatatttc aattatctat aactaatgat
    11821 aaaatgaaaa gtaaagtcta catagtctgg ataatacaca gaaggaaaag gagattacac
    11881 aacgcatggc caatttgatt cgttcactta tcgaaaacga taagaaagaa ctaaaacgtt
    11941 tagatagcat tgcaaaaaaa gttgaagcat acgctgacca aatggcagca ttaactgatg
    12001 aacaattaca ggcaaaaact gctgaattca agggcagata ccaaaaagga gaaacattag
    12061 atcaattact tccggaagct tttgcagtcg tccgagaagc agcaaaacgt gtattaggtt
    12121 tatatccata ccacgtacaa ttgatgggtg gaatcgtgct tcacgatgga aatatccctg
    12181 aaatgcgtac tggtgaaggt aaaaccttga ccgcaacgat gccagtatat ctaaatgctc
    12241 tgactggcga aggggtacac gtagttaccg tcaatgaata tttagcaacc cgtgactcga
    12301 cggaaatggg cgaactttat aatttcttag gattaacagt ggggttgaat atcaactcaa
    12361 aatcttcgga tgaaaaacgc gaggcttata attgtgatat cacttatagt acgaataatg
    12421 aattaggatt tgactacttg agagacaata tggtcgttta ccgccatcaa atggtacaac
    12481 gtccgctgaa ttatgccatt gtcgatgaag ttgactcaat cttgattgat gaagcgagaa
    12541 cgccgctgat catttcaggg caagcagaaa aatccacagc tttatataca agagcagaca
    12601 acttcgtgaa acgtttgaaa gaagaagaag attataaaat cgatgtacaa tcaaaaacaa
    12661 tcagtttaac cgaagcaggg atcgaaaaag cagaagaaac attcggtttg gataacttat
    12721 acgacattga aaatactgca ttgacccatc acttggatca agcattgaga gccaactata
    12781 tcatgctttt agatatcgat tatgttgtcc aagacggaaa agtactgatt gttgaccagt
    12841 tcactggtcg gatcatggat ggacgccgtt attcagatgg acttcaccaa gcaatcgaag
    12901 ctaaagaagg cgtagagatc gaagacgaaa cgaaaaccat ggcgacgatc actttccaga
    12961 actatttccg tatgtacaag aaacttgcgg gaatgactgg tacagctaaa acagaagaag
    13021 aagaattcag agaaatttat aacatccaag tataccagat tccgacaaat cgtccggtta
    13081 tccgtgatga tcgtccagat ttgctttacc caacattaca aagcaagttc cacgctgtcg
    13141 tgcaagatat caaagatcgc taccgcaaag gtcaacctgt gttagtcgga actgttgcgg
    13201 ttgaaacatc tgagttatta tcagatatgc tgaatcaaga acgtattcct catgaagtgc
    13261 tgaatgcgaa aaatcacttt aaagaagcag agatcatcat gaatgctggt caaaaaggtg
    13321 ctgtgacgat tgctaccaac atggctggtc ggggaacaga tatcaagtta ggacttgggg
    13381 taagagaact tggtggtcta gcagttatcg ggacagaacg acatgaatct cgtcgtatcg
    13441 ataaccagct tcgaggacgt gcaggacgtc aaggagaccc tggtatgtca cagttctact
    13501 tgtcattgga agatgatttg atgaaacgat tcggttcaga acgaatcaaa gctttcttag
    13561 atcggatgaa gatcggtgag gaagatgctg ttatccaaag caagatgctg acgaaacaag
    13621 tagaatctgc acaaaaacgt gtagaaggaa ataactatga cacacgtaaa aacgtcttac
    13681 aatacgatga tgtgatgcgt gaacaacgtg aagtaatcta taaacagcga caagaagtaa
    13741 tcatggaaga aaaaagctta tccaagccac taatgaacat ggtcaaacgg acaatcagtc
    13801 gtgtagtaga tgcgcataca caattagaga aagaaaactg gaatttggaa agtatcatcg
    13861 attttgccgg cagtactctt gtccatgaag atagtattac tcttgcagat atcgaaggaa
    13921 aaacagctca ggagatcaaa gagtatctaa acgaacgagc acaagaagta tttaatacca
    13981 aagcggctca actaaatggt ccagagcaac tgttggaatt tgaaaaagtc gtgatcttgc
    14041 gtgttgtgga ctctaaatgg acagaccata ttgacgcaat ggatcaatta cgtcagtcaa
    14101 tcggcttacg tgcttatgga cagaacaatc cattagtcga atatcaaaca gaaggctata
    14161 agatgtttga agatatggta ggcgccatcg agtatgaagt cactcgaatc tttatgaaag
    14221 ctgagatccg tcaaaacgta cagcgtgaac aggtttctca aggaacagct tctcactcag
    14281 aagacggaga tgccaaagaa aatagtaata ctagcgcgaa aaaacagcca atccatgtga
    14341 acaaggtcgg aagaaatgat ccttgtcctt gtggaagcgg gaaaaaatat aagaactgtc
    14401 atggaaaaaa tgcaaactaa tttctgacag caggattggt gagacaaatt ctttttttaa
    14461 gaattcgtct caccttcttt ctgttatttg ctgattctgt tagactagat ataatgaaaa
    14521 aagtatagtg aaagaaggaa aaaacatgga aatatccgaa attcgaaatc tcctgacaga
    14581 aatgcaggaa aaggtcacaa gtttcaggag gtctctttga cttagatcag ctggaagaag
    14641 acatcgcgga agcagaagca aaaatggctg aacctggttt ttgggatgac agcgaagccg
    14701 cacaaaaagt gatcagtgaa aataacgcta ataaagaaac ctatgaccaa ttccattctc
    14761 ttgccgaaga actagaagaa atcgaattga tggtggagat gctgcaagaa gaacctgatg
    14821 cagcaatgca agaagaagca gaaacacgta tcaatgcatt agatgaaaaa atgaagacgt
    14881 atgaattatc tatgctgtta gacggacctt atgatcgaaa caatgcgatc gtcgaattgc
    14941 atccaggggc tggcggaacg gagtcccaag actggggcag catgctttta cgtatgtata
    15001 cacgttgggc agagcagcat ggctatcaag tagaaacact agattatcaa gcaggtgatg
    15061 aagcagggat caagagtgtg accctgctga ttaaaggaca taacgctttt ggttatctaa
    15121 aatcagaaaa aggtgttcat cgccttgtac ggatttcgcc ttttgactca gcgaaacgac
    15181 gtcatacttc tttttgttcg gtagatgtga tgccagagct tgatgaaacg atcgatatag
    15241 aaatcaatcc agatgatttg aaaatcgata cgtaccgagc aagtggtgca ggtggtcagc
    15301 acatcaataa aacagaatct gctgtacgga tcactcactt gcctacagga acagtagtag
    15361 ctagtcaggc acaacgctca caattgaaaa accgtgagca agcgatgggg atgttaaaag
    15421 ctaagcttta tcaattagaa gtggaaaaga aagaacaaga agcagctgca cttcgaggag
    15481 aacaaaaaga aatcggctgg ggttcacaga tccgttctta tgttttccat ccctattcta
    15541 tggtaaaaga ccatcggaca aacgtagaga caggaaatgt ccaagcagtt atggacggtg
    15601 accttgattt atttattgac ggctatttaa aaatgcatct acaataagaa cccattgtta
    15661 aattgaaata aaattgtaag attttgcaag catgttgaaa cattgccatg ctataatagc
    15721 taaagactga aaaagatatg gagagaacgc catgattgaa atgaaggatg taatgaagaa
    15781 gtactcaaat ggtacgaccg ctatccgcaa tctctcgatt gtcatcgaac aaggagagtt
    15841 tgtctatgtg gttggtccgt ctggagccgg taaatctaca ttcatcaaat tgatgtatcg
    15901 agaagaaaaa gcttcaaaag gaactttgaa cgtcgcaggt catgatctaa tagcaatcaa
    15961 aaaccgcgaa gttccttatc tacgcagaga aatcggcgtg gtgttccaag actataaatt
    16021 attaccaaga aaaacagtat atgaaaatgt tgcgtacgct atgcaagtta tcggcagaaa
    16081 acctcgagat atcaaaaaac gagtaatgga agtgctggac cttgttggtt tgaaacacaa
    16141 agttcgagtc tttcctagcg aattatccgg tggggaacag caacgtgtct ctattgctcg
    16201 ggcaatcgtg aatacgccta aagtacttat cgcggatgaa ccgacaggaa atctggatcc
    16261 agaaaactca tgggaaatca tgaaattatt agatcggatc aatgcccaag gaactactgt
    16321 cgtgatggct acacataaca gtacgatcgt aaatacgatt cggcaccgag taattgctat
    16381 cgaaaacggc cgcattattc gagatcaagc ggaaggggaa tatggatacg atgattagaa
    16441 cctttttccg ccatttatta gaaagtatca agagtttgaa acgtaacggc tggatgacag
    16501 ttgcttcagt cagtgcggta acgatcacgt tgactttagt cggtgtattc atggcagtta
    16561 tcatgaatgc aactaaatta gctcaggata tagaaggaaa cgttgatgta tctgtattcg
    16621 tagatatcgg tacaaaagac gaagagatga aaaagctaga aaaagaattg aatgacttag
    16681 atcatgttaa aaaagttgaa ttttcaagta aagaacagga attgaaaaaa atccaaaacg
    16741 aaatgggtga ttcctggaaa ttgtttgaag gtgacaataa cccgttatat gatgtgtatg
    16801 tagtaagtgc tactgatcct tcttatacaa aacaagtagc agaagaagca gcagatttga
    16861 agaatgtttc tcgttctgat tacggtggag cttcctcaga tcggattttc caaatcgctg
    16921 gtgcagttcg gacatgggga ttagttgcag cggcattgct gctgttcgta gcgatgtttc
    16981 tcatttcgaa cacgattcgg atcacgattt tgtctagaca gcgtgaaatt caaatcatgc
    17041 gtttagtcgg tgcaaaaaat ggatatattc gctggccgtt tttccttgaa ggtggctgga
    17101 tcggtctgat cggtgcgatt cttccgattt tgatcatcac atttggttat gcatggtttt
    17161 tccaattgat caatccatca ttattacgtt cccattattc attgattcat ccacaaaata
    17221 tcgtttggaa aatcaatctt ttaatggtcg gcattggtgt gatcattggt tcacttggct
    17281 cgatcatttc tatgagacgt ttcttgaaat tctaatacca caatataaat aaaatgagaa
    17341 agttggacag tttcgttcca gctttctttt tttattggct aggagaatag aaggaagcgg
    17401 cttttttccc tttactttaa aaaacaactt gggtattctt aagttggtag aggaagaggt
    17461 gaagccgtga aaattatcgt tgacaatttt tttacgatcc ttttgattat gaatattttg
    17521 ctttccttta tcatcgtttt tcgagaaaga aaggaaactg ctcaaacatg ggcatggctg
    17581 ctcgttttga tgttcattcc agttgtagga tttattttat atattttttt aggaagaggg
    17641 atttccaaag agaaaatctt tgatttgaag atccaaggga aaatcggtaa gaacctggaa
    17701 attgaagaag acaaacaggc attgatgcga gggctttatc ctcatccgcc tactggacaa
    17761 gtagatgtga aacaattgat ctatatgctc acggtatttg aaagtacgct ctatacgact
    17821 aaaaatgaaa tcactttatt tacagatggt cgtgaaaaat tcgatgcgct gattgaagat
    17881 atcaagcaag cagaagacca tatccacttc cagtattata tttatcgcag tgatgcatta
    17941 ggtgaagaag ttcgagatgc attgacagag gcggcaagac gaggggtaaa agtcagagtc
    18001 cttcttgatg catggggttc cacacaagtt tcttccagct tttttcagaa tttgaaaaaa
    18061 gcaggcggag aaatcgcatt tttctttcct ctatttgttc cgtatattaa tcctcggatc
    18121 aattatcgca atcatcgtaa aatcgtagtt attgatggga aaatcggata tacaggtggg
    18181 ttcaatgttg gaaatgaata tctaggattg gtaaagaaat ttggttattg gcgagacaat
    18241 catttgcgta tttacggaga agcggtgtat atcttgcaaa accgtttttt gatggactgg
    18301 aattctcagc atacaaaaga agtaggctat tctcccaaat tttttccgtc cattcactct
    18361 actggtgata tagctgttca aatcgtgaca agcggaccag ataccgaaca tgaacaaatc
    18421 aaaatgactt atttgaaaat gatttcgtta gccaaacggg agatattgat ccaaacgcct
    18481 tattacatac cggatggatc gattcatgaa gcactgaagt tggctcttct ttcaggcgta
    18541 aaagttcata tccaaatacc taacaaacca gatcatcttc tcgtttactg ggcaacgtat
    18601 tctttcgctg cagagctgat cgagtatgga gcaaggatcg aaacatatga gaatggattt
    18661 attcatgcaa agacgatgat tatcgatggt ggcattgttt cagttggctc agcaaatatc
    18721 gatgttcgtt catttcgctt ggactttgag gtcaatacac tgatttatga tgaacgaatg
    18781 gcttcacgtg taagaaaagc attttttgaa gactcgaaaa tttctacgca tctcacaaaa
    18841 gaaatgtatg aaaaccgagg aataatcatc aagatgaaag aaggattagc aagattgatt
    18901 tcgccgctcc tttaaaacac aaaaaggaca tgagaaccat caacagatgg agatctcgtg
    18961 tccttttcta acggggccat ttctgagagt acgtcagaaa tggagaaagc gtctcgcatg
    19021 agcgaaatta actttggggt atctcttgtt ttttggggaa agcaag
//
LOCUS       DAFBSV010000057        18201 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.058, whole genome shotgun sequence.
ACCESSION   DAFBSV010000057 DAFBSV010000000
VERSION     DAFBSV010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18201
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.058"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(56..424)
                     /locus_tag="LLB18_001841"
     CDS             complement(56..424)
                     /locus_tag="LLB18_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HBK5244839.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            595..1551
                     /locus_tag="LLB18_001842"
     CDS             595..1551
                     /locus_tag="LLB18_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBK5244840.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            1624..1740
                     /locus_tag="LLB18_001843"
     CDS             1624..1740
                     /locus_tag="LLB18_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HBK5244841.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(1795..3477)
                     /gene="recN"
                     /locus_tag="LLB18_001844"
     CDS             complement(1795..3477)
                     /gene="recN"
                     /locus_tag="LLB18_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBK5244842.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(3495..3944)
                     /locus_tag="LLB18_001845"
     CDS             complement(3495..3944)
                     /locus_tag="LLB18_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBK5244843.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            complement(4051..4869)
                     /locus_tag="LLB18_001846"
     CDS             complement(4051..4869)
                     /locus_tag="LLB18_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HBK5244844.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            complement(4878..5768)
                     /locus_tag="LLB18_001847"
     CDS             complement(4878..5768)
                     /locus_tag="LLB18_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBK5244845.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            complement(5770..5994)
                     /locus_tag="LLB18_001848"
     CDS             complement(5770..5994)
                     /locus_tag="LLB18_001848"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBK5244846.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            complement(5999..7336)
                     /locus_tag="LLB18_001849"
     CDS             complement(5999..7336)
                     /locus_tag="LLB18_001849"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBK5244847.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            complement(7337..8191)
                     /locus_tag="LLB18_001850"
     CDS             complement(7337..8191)
                     /locus_tag="LLB18_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HBK5244848.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            complement(8288..8737)
                     /gene="nusB"
                     /locus_tag="LLB18_001851"
     CDS             complement(8288..8737)
                     /gene="nusB"
                     /locus_tag="LLB18_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBK5244849.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            complement(8730..9155)
                     /locus_tag="LLB18_001852"
     CDS             complement(8730..9155)
                     /locus_tag="LLB18_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBK5244850.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            complement(9401..10465)
                     /locus_tag="LLB18_001853"
     CDS             complement(9401..10465)
                     /locus_tag="LLB18_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBK5244851.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            complement(10637..10882)
                     /locus_tag="LLB18_001854"
     CDS             complement(10637..10882)
                     /locus_tag="LLB18_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBK5244852.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            complement(11021..11395)
                     /locus_tag="LLB18_001855"
     CDS             complement(11021..11395)
                     /locus_tag="LLB18_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HBK5244853.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            complement(11478..12392)
                     /locus_tag="LLB18_001856"
     CDS             complement(11478..12392)
                     /locus_tag="LLB18_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HBK5244854.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            complement(12413..13216)
                     /locus_tag="LLB18_001857"
     CDS             complement(12413..13216)
                     /locus_tag="LLB18_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HBK5244855.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            complement(13249..14238)
                     /gene="manX"
                     /locus_tag="LLB18_001858"
     CDS             complement(13249..14238)
                     /gene="manX"
                     /locus_tag="LLB18_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HBK5244856.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            complement(14341..14832)
                     /locus_tag="LLB18_001859"
     CDS             complement(14341..14832)
                     /locus_tag="LLB18_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5244857.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            complement(15023..17830)
                     /locus_tag="LLB18_001860"
     CDS             complement(15023..17830)
                     /locus_tag="LLB18_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK5244858.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
BASE COUNT         5234 a         4012 c         2995 g         5960 t
ORIGIN      
        1 aaaatcaagc tgcaaaaagc cttttaaaag actttttaca gcttttctat ttttttcata
       61 ggtaagaaag tatgttcaca atgatcaaga cagcgtacaa gacgattgtc aacagaaaaa
      121 ccaaacgcca agtcatcttg aaataacgcg gataaataat ttcttcataa taatatgctt
      181 ggaaaacagc aatacaaatt cccattagca aaacagaaat aaagaaaaac ggtaagatag
      241 aaattgtccc tgtatttcta gacaatgcat gcataccgcc ccacaaaaaa ggaatcgcca
      301 aatcaggggc ttttatttta aaacgacgat ttaacgaaaa taattttaca agaaattggc
      361 aaccaaacaa aacgattacc gggtaaatat accaaaacaa gataagtggt gtgaatgtgc
      421 ccatgaacgt aaactccttt tttatcgttg cttcaagtat actgtatata ctttacacaa
      481 ctgtttcatt ttatttaaat ttatgcagtt atattctata tcttacaaac acattccatg
      541 tattccaatt ccctatccgt tataataaaa gaaacaggca acaggaggaa aatcatgatc
      601 aaatatttta cattagataa tgagaaactg cgtaataccg gaaaggaaac tgaccaaacg
      661 atctggtatt gtgtagaacg tcctaatcaa gaagagattc atcagctgac acatcaattt
      721 gaaattccgt cagattacat cacttccata ttggacgatg cagaaaattc ccgtacagaa
      781 gaattcaatc aatcaaagtt gacaaagcca gcgttattat tgttacaata tccttttgct
      841 aaaacaagtc ctagcggtta ttttcaagtg gatacatacc cgctctctat tattttgacg
      901 cccaaaaaga agcttatcac aattacgaat catgaaccac tgtttttaaa gaaagtcttt
      961 agccagacct ttccaaaaag tgatatttcg cctaatctca atatcttctt tcaattcatt
     1021 tggcaggtca cactctctta caacagttat ttagctacgc ttcaatctca atgcgatact
     1081 ttggaagcca aacttcaagt atccactgaa aacaaacaac tttatcaaat catggatatc
     1141 caaaaaagcc tcgtttattt cagagaagcg acttctgcta atttagatgc attgaaagaa
     1201 ctagcgcaaa ataaactttt ccaagaaaat catgctttga aaaatcattt acgtgatgta
     1261 ttggtggaaa cagagcaggc aatgactact tctcgcattc aattaaaact agtagaacaa
     1321 atgaatcaga ctttttcagc aatcgtatcg aataatctga ataatattat gaaaatttta
     1381 acttctttaa cgattatttt aactataccg acaatcgtcg gcagtatcta tggaatgaac
     1441 attaagttac ctattgctga aagggatgat gcctttatat ggctagttct attaacatta
     1501 tttatttgta tcgtaactac ctattattta aaaaaaggga agtttttata aaaaagccct
     1561 cttgtggaaa tggaaaaaag attgtacact tgaatcaact aattaatgac gaggttgaaa
     1621 acaatgcgtg aaaaaaaaca aacaagtact tttgctaaag taacaaaatt tgtcatttgg
     1681 acaatgctga ttttaacgat tggatctgtt gtattgactg ctgtaatgag tgtcatgtaa
     1741 aaataaaata tagctatcag ctgctgaaaa ggacctgaac cactgagagg tggctcaggt
     1801 cctttttgcg agtttcaata gttcttttgc atgttcgagt gtgagttttg taatctcact
     1861 tccagccagc atacgtgcaa tttcttcttc tctttctttt gttttcaact ctgaaacaga
     1921 agtttgcgta cgtccatcaa tcactgcttt cacaatataa tattgatagt cggcgactgc
     1981 agcaacttga ggcagatgag tgatgcacaa aacttgagag tatttcgata tttgagaaat
     2041 tttatctgcg atggcctgtg caactcttcc gctcacacct gtatccactt catcaaaaat
     2101 aatacttgtc acaccttgct cagaagaaaa aatagttttc aaagcaagca acatccgaga
     2161 cagttcgcca ccagaagcga ctttcaccaa aggcttcagt ggctctcctg gattggtcgt
     2221 aatgtaaaat tcgatttggt caaatccatc atgattcaat tgtctatttt cttcttttaa
     2281 gaaacgtacc tcaaactcag tgttttccat atacagactt ttcaattcat gcagaatgga
     2341 tttttccaat tcttttgcga tttttttacg cgcttcatga agatctgcgg cttgttgctg
     2401 aagtagaagc tctttttgct ctagttcctc tttcattttg tccaattgac cttctgaaaa
     2461 atcagaagaa gctagctctt cggtgatttc gtcatagtaa gccaatattg actcaatgga
     2521 ttcgccgtat ttacgtttca actgtcggat taattctaaa cgttgcgtaa cttcttctaa
     2581 acgactctca tctaactcca ataaatcaat ctgacgactc atatcgccga ttgcatcttg
     2641 cagcaaatag taagcacttt ggatattttc ataaattgct tcatactcca catctagatg
     2701 ggcgatccct tgcagttctg aaacggccaa gccaacacca tctacactgt tttgttcatt
     2761 attcgtcagt gctccgtaac ctgcagctaa tccatcagca attttttgat aattgctaag
     2821 tttttctctt tcttctttta atttctcttc ttctccgact tgcaaatcag cagcagctat
     2881 ttcttcttgc tggaaatgga gcatatctat tctctgaaca taggattttt cattttgctg
     2941 cacttttcgt accctttttt ccagctcacg ataagagata tattcttgct gataactctt
     3001 tttcttctgt tggaaagcta catctccaaa acgatccaat aaagcaagat gtgattcagg
     3061 ctggagcagt tcctgatgtt cgttttgtcc ttggatatct actaaataac tgccgattct
     3121 tctcagatta gctaatgtga taatatgacc attcactcga caaacatttt ttccagttaa
     3181 ggacatatcc cgtcgaacaa tcagattgtc ctcatctgtt tcgatcccta attcaaccat
     3241 cagttcagag aatccttctt gttttggtag ttcaaacaac ccttcaagca cacatttttc
     3301 tgctccttga cgtatataat cgcttgaacc tcttcctcct gctaacagac ctaaagcatc
     3361 gataataatg gatttacccg caccagtctc tccggtcagc gcggtcattc cttcgtgaaa
     3421 agaaagccgc aattccggaa taatcgcaaa gttagtaata ctgatttctt gtagcatcac
     3481 attcgctcct caacttaaag gtaatgcagg aagtctttct tcaataaaac tgcctggtct
     3541 tcagttcgtg taatcatcaa aacattatcg tcatcattga taatcgaaaa taattctttc
     3601 ttgtaacgtt tatcaatcaa atttgctgct gccgaagcat ttcccggcaa tgttttcaaa
     3661 ataacaaatt tttccatttg gtcaactgcc acgaaagcgt cttttaatag tttttccaat
     3721 ttagtattta catcttcgtt tgtttcagct ggtatgctat aacggtagcc gccatctgaa
     3781 gccggtacct tgatcagttt cagttccttt atatctctgg aaatcgtagc ttgagtaaca
     3841 gatattcctt tgcttttcag gatttcaaca aattcttcct gctttcggat atcttgctca
     3901 ctcaacaatc gagtaatcaa acgatgccga tctttttttc tcattacgtc ttcgctcctt
     3961 agcatattct tcttaatcaa tgatagctta tttccttggt ataataaaga agaatccgca
     4021 tacttctcac ttgattttca cagttacaat ttatttatgg tcaaactgtt cgtgtgcatt
     4081 tgaaaccact tctgccatat taatagctga attgattgtt ccgctttcgg gtactttcct
     4141 caagtgagcc aagaactcga tatttccttc tccccccgtg atcggagaat aacttaattc
     4201 cagcacatca tatccacctt gtgccgcaaa tgacaaaatg tcttctaaaa ctttttgatg
     4261 ggtctgaggg tcacgaacaa ttccgttttt ccctacagct tctctgcctg cttcgaattg
     4321 gggtttgatt aaagcaatca cttctccctc ttcttttaaa atagcatgta atggaggcag
     4381 catcagtttt agtgaaataa aagaaacatc gataacagca acttctggaa ttcctaaggt
     4441 aaagtcttcg ggttttgcat aacgaaaatt cactctttcc attacgacga ctctaggatc
     4501 ttgtcttatt ttccaagcta gctgattgta gccaacgtct aaagcataac tcatttttgc
     4561 gccattttgc aaagctgcat cagtaaatcc gccagtggat gcaccaatat ctaacaatgt
     4621 ttttccttca acagatagat caaatgcttt gagtgctttt tctaatttta atccccctcg
     4681 agaaacataa ggaagttttt tacctttgac tcttaattca ctactcactg gaattttttc
     4741 tcccggttta tcaaaccgct cgtttttttc gttgtaaatc aaaccagcca tcactgaacg
     4801 tttggcttgt tctcttgttt caaataatcc ttgtttgacc gctaatacat ctacgcgttc
     4861 tttttccatt ctttccctca tttctccaca tcaaattgct tgatcatctg gcgcatcagc
     4921 ccgccatcaa aagaaaaaac gtcctcttct aatttgtcta tgatcttgtt ggcggataac
     4981 agctcaatct ccaacgcctc acgtgtcttt tctaggccta ataaacgcgg gtaagtattt
     5041 ttttccatac gttcatcttt accagctgtt ttccctaatg ttttcgttgt accaatcaca
     5101 tcgagtagat catctcttat ctgaaaagct aaacctaaat gttcggctaa tcgttgaagt
     5161 agcaataaga tttcttcagg ttgcttcgct aatatgccac cagccagcaa ggcataacga
     5221 atcaaatgcc ctgtctttct ttcatgaata aatgctaatt cttctaaaga aagctttttc
     5281 gattcgccct cgatatctgc agcttgccca gcaaccatac cttgtgatcc cgcacaaaca
     5341 gctaattgct gaagcagcag aagcttagga gaattaccta agtgtgccat actgattagc
     5401 tggaatgctc ctgtaagcaa accatctccg gccaatatag ctaatgcttc gccgaatact
     5461 ttatgattgg taggttttcc tctacgaaga tcatcattgt ccatcgcagg caaatcatcg
     5521 tggatcaagg aatacgtatg caccatttct aaagcagctg ctacttgata gacgggaaca
     5581 tcaataggct catcaaagga agcaacggcc gttaaaagta ataagggacg tattcttttc
     5641 ccgcctgctt tcactgaata actcatcgca tcatagagtc ctctatccgt tgtatgctca
     5701 tctaaaaaag acaagatttc tttttctaca gcaggtagat gaatagctga aaagtcagtt
     5761 aatctcatct cagctttcct cgtttccgtc aaaatcaact tcttcatttg attctgtcat
     5821 cattttcgtc aaggtctctt ctgctttagc taatgtatct tggcaatgtt tgcttaattc
     5881 cattcctcgt ttaaacgaat ctagagctga ttctaatgga acgtctcctt gttctaactg
     5941 catgacaatt ttttctaatt cttgcagtga ctcttcaaaa gttggatttt ccatattttt
     6001 attctccttt gtctatctct tgtacttgtc ctttaacgat tccatcttga taatggatcg
     6061 tcagcaaatc cccttgatga atctcggtga cactttttac tacttgatca tttaacgtcg
     6121 tatagctgta gcctcttccc atgattttca atggactcaa caaatcaaga gattgaacag
     6181 cttgagcaaa acgctgctgc tgttgtttca tatattgttg gattttctct tctaagcgtt
     6241 tttctagata agcagtttct tggcgagctg ctttaactcg ataaagcgga gccacttgtt
     6301 ccaattggtg gcttaatgcg atcgtttgtt tttctttcgc atgataaatt tgctgtgtag
     6361 cttgatataa tcgctgtttc aactggtcta atttgatggt ctgaccttca tacaatcttt
     6421 caggctgccg aaatacatag gaacgtcgag cacgctcgaa ccgttcttgt ttgcgctgga
     6481 tctggcgtac aaacgcctgc tgcaatctag cttgccgttc ttgaatgcgc atcaactctt
     6541 ctgacaaaac aggaacagct aattctgcag ctgctgttgg agtggcagcc cgaacatctg
     6601 ctactaaatc agcgatcgtg gtatctgttt catgtcctac agatgaaatc accggcgtat
     6661 tagcttgata aatcgcccga gcaacccgct cttcattaaa cggccataaa tcctcaatcg
     6721 aaccaccccc acgaccgatg atcattgtat cgaaattgcc catctcttct actctctgga
     6781 tattcctgac aacattgtcc gctgcttggt ttccttgtac aactgttggg aacaaaacca
     6841 attggacaat tggatatctt cttttcaccg tcgtgatgat atcgcggata accgctccgc
     6901 ttggactggt aaggaccgcg attcgctttg ggaaacgtgg cagcattttt ttaggccctt
     6961 gaaaaaggcc ttccttcatc agcttttctt ttcgttcttc caattcttga tataaagcac
     7021 ctattccatc aggctccatg tgctctacat agatttgata agaacctccc gcttcatata
     7081 atgaaatacg cccaacgaca aggactttca ttccttcttt tggctggaat cgtaattttt
     7141 ggaatgctcc tttgaacata atagcagata tttttgcatg gtcatctttt aagctgaaat
     7201 attgatgggc attggcacgt aaacggaaat tcgatatttc gcctgttaaa tatacgcgtt
     7261 ctaaataagg atcggcatca aattttcttt tcaaatactt cgttaatgta gtgacagtta
     7321 aatattcttg tgccatctat tcacctgctc caaaagcttc ggcagatttt acggtttgat
     7381 acatcagcat cgtgatagtc attggcccta caccctttgg cacaggagtg atccagcctg
     7441 caataggctc cacttcatca aatttcacat caccgatcag cttaccgtta gcatcacgat
     7501 tcatccctac atctatcact acagcacctg gttttacgaa ttcttttgtg acaaaatgtc
     7561 cacgtcctat tgctacgact aaaatatctg cttcttgtgc cagttcagcc agattttcgg
     7621 ttttagaatg agcaacagta acagttgcat ctgccatcaa gagtagctga gccatcggtt
     7681 taccgacgat attgcttcgt ccgataacta ctgctcgttt acccgccgga tcgatagaat
     7741 aagcttcaaa cattttcatg atgccgtatg gagtacaagg aatcttgtcc ggtttacccg
     7801 caaggagtct gcctaaattc atcggatgaa aaccgtctac gtctttttca gggcggatag
     7861 ctaacaggat cttttcttca tctatatgct ttggcaatgg taattggacc aatataccat
     7921 gaaaactagg atcttgattg tatttttcaa tttctgcaag tagttcgtct tcagaaatcg
     7981 tctcaggata acgctctacc aatgaatgga ttccgatttc ttttgctaca cgttctttat
     8041 ttcttacata gatttggctg gctggatttt cccctaccaa taaaacgact aatccgggat
     8101 ggataccatt atctttcaat ttttggattt tttcagcaat ctctgcctgc attttttcag
     8161 ctaattcttt tccgttaatc aattctgcca tctaaccact cccagatatt ttttgtgttt
     8221 tcattctacc atagaatttt cccgatttat aacaggttta tgatgattca tagaaaaaag
     8281 ctaggactta cgccccagct tctaattctt tcaatacatt ggataaaaca ccgttgacga
     8341 atttacgtga acggtcatca ctaaatgttt ttgccaactc gattgcttca tttaaagcaa
     8401 cagccgctgg tacatctgtc acataagtca tttcaaaaat cgcgatacgc aagatcacca
     8461 aatccatttt tgagatccga ttgatgtgcc aattgttttt taaatgtttt tcaatcactt
     8521 tatccaattc atcttttttt gcacagacac cgccaactag cgtatcaaga taaacaggaa
     8581 caaactctga ttcatcttcg ttgatcatgt cgcggtggtc taattcgatt gcgttgaaaa
     8641 tcgcatcttc ttttgttagg tctgcattga agtctaatgg aaataaagcc tgcaatgcca
     8701 tttcccgaat ctcgtgtctt gataattctt tattcattct cttcctcttc gtcttcaaaa
     8761 agttcttcga ttgttggttg ttctaatttt tcaggaacaa cagctactac atggatattg
     8821 acttcagata aatcgatatc cgtcatgaaa aggacttgct ggctgacccg ttcctgcatt
     8881 tccattgcta ctttaggaac tgaaacacca tattctagat aacagtaaag atctactttc
     8941 aagccatctt cctcgtttgc taagtaaaca ccttttccgt gagctgcacg tcctaataat
     9001 tcagtgacat tgctggcaaa agttccgcgc attccgtata cgccttctac tttagaagct
     9061 gcaatcccga taattacttc gatgacttca ggagcgatca cgatctctcc taaatcttgg
     9121 tttgcgttta aaatcaaatt tttttcatct gccatttatt tattcctccc tttgcctaag
     9181 cacgagatac atccgaattc tctatgatgc ggcatagtga tcacgtggta agaaaactgc
     9241 cgccgatcag ctgcaaactg ctatgaattg gagaaaacac ccaactttat tatctcttac
     9301 agcttaaaag ttcttctata gtgtatcatt aaatcgagtg attttctata acaaagtctg
     9361 tgaacactga tttttacgct tacttcttct attgatgaaa ctataagatg atcaattctt
     9421 ttggtgaacg agtcaacaca cgatttccat cttctgtgat caacaagtca tcctcaatac
     9481 gtactccacc gattcctggt aagtagatcc ctggttcatc agtgatcaca tttcctggta
     9541 caaattgctt ttctgcacga gaagaaacgt ttggtccttc gtggatctct aaaccgatcc
     9601 catgtcctgt agaatgtcca aatgcttccc cgtaaccatg ttttgaaata taatctctag
     9661 caactgcatc taattggaca ccagtcattc ctggttttgc agcatcaata actgctaatt
     9721 gagcatctaa gactatttga taaatttctt ttaatttttc cccaggatca ccaatagcga
     9781 atgtacgtgt catatcggaa acgtaccctt cgtaatagca accaaagtcc aatgtgatca
     9841 agtcaccttg ttcgatgatt tttttgcttg ctacaccatg cggcatagcc gaacgcaatc
     9901 cgctagcaac gatcgtatca aaagaaacac ctgaagcgcc aagagaacgc atataaaagt
     9961 ctagttgatt tgcgacttca atctcagtca tgcccggttg gatcattttc aggatgtgat
    10021 catatgccat atccgcaata tgacatgctt tttcgataat agcgatttct tcttcatctt
    10081 tcacttctct gagttcttcg atcatctgtg aaacaggtac taattccgca tcgatgattt
    10141 cttctaaaac cgaatattct aaaaatgaga ctgttgtttc ctcaaaagct aatgagtgca
    10201 gttcttcttt gcgtactaag tttgctacct catcaaaaat aggtccgaca tttttaataa
    10261 tttcaaaccc ttgagcctgc gctgccgcct gctcggtata acgaaaatca gtaataaaaa
    10321 atgctttttc caaagtaata acagctaatc ctgtcgtacc tgtaaagttc gttaagtaac
    10381 gaagattgta cggactggta accaaaaatg aatccaaatt ttcttcttgc atttttttgc
    10441 gcaatttttc tacacgtagc atcataatga aactccctct ttctttgcac gcttttttcc
    10501 attatagcaa acttttcttc gtacacgaca gttaaataaa aatttccgga aaacttcttt
    10561 ttattttaaa taaataaagc caaaaaggag tcacagtctc gctgcaactc cttttagttt
    10621 actattttgt aaaaacttat gatcgttttc caaagaaaaa tgagacaact gctaccaaaa
    10681 tcactgcgcc taaaatagat ggaataagtg ccatacctgc agcttttggt ccccattcgc
    10741 cgaaaatcgc ttgtccaata cttgaaccga ctagtccagc aatgatattc gttacacagc
    10801 ccatcgaatt tcctttactg gtgatcgcac ctgcaattgc tccgatcacg gctccaacaa
    10861 tcaatgtcca taaccaactc ataatataac ctccttcttt gctaatcaat tttagcatat
    10921 gggatttaaa ggggacaaat aattggtttt gctatttcat attttcttct gcaaagtaaa
    10981 aaaataaaga aaacctcctc ttagaagttt tctttatttt ttacttgcgt ttaaacatac
    11041 tacgaatacc acgtttcact acatcaaaga aactcaatga ttgtaccatt ctatcttcat
    11101 ctacatattc tctgatcgca cgaagcactt ttttaggttc tttggaagaa aatgtgtatg
    11161 taccattttt tttcgtttga atggcatatc gaggaatcca ttttcccttt agcatgactg
    11221 atgctagtac ataatccact tcttcccatg gaatttggat atatttgcgt ctatctcgcg
    11281 catggtaaaa ctcaaaacca ttatcaccta tcatgatttg cccgtaatct gtcagacccg
    11341 taaacgaagt agcatcaatt accaagtcta cttttgtatt gattgattga accattttct
    11401 ccctccagat atttgtttat gaacagtata ctatataaaa aaagctcggg acaacgcccg
    11461 agctatattt ttatggatta taaaagtccg atgacgtgtc caacaacacc gactacgaat
    11521 aaaccaagga tgataacgat tggagaaacc tttttcttaa gcaaccacat acataacaat
    11581 gttaatccta atgcagctaa accaggaatc aattggtcta agttgtcttg taatgttgtt
    11641 accttttcag gagaaagggc taagccatta ttaacttgtt caaatgcact cttgattcct
    11701 tcaccacctg aaggcaattt atcccattcg atgtaagcac ctttatctaa ttttacagtt
    11761 gatacaactg gtaagaattt gattgatacc catctttgta caagggcagc taatacgaac
    11821 atccctaaaa ttgaagcacc ttttgttacg tcttgtaaca atccgccaga aaggtcatca
    11881 gtaattttag aaccagcttt gtagccaaat tcttgtgtat accacatgaa tgcccaacga
    11941 ataatgttcc aacctaagaa gaagatgatt ggtccaagga tatttcctcc catagctaat
    12001 gaagcaccta gtgcacctag cattggacgt actgtaaacc agaacactgg gtcaccaaca
    12061 ccagctaaag gacccatcat acctacttta accccttgaa tcgctacatc atcaacaggc
    12121 gcgccattcg cacgttcttc ttccagagcc aatgtaaccc ctaaaattgg agaagcaatg
    12181 tatgggtgtg tattaaagaa ttccaagtga cgttttaatg ctgcagaacg ttcttctttt
    12241 gttttgtata attttttgat tgctggaatc atagaaaatg cccagccacc gttttgcata
    12301 cgttcgtagt tccatgaacc ttgaatgaag gtagagcgcc acgcaacagc taaacgatct
    12361 ttttttgata atttgatttt ttcttctgcc attttatttt cctccttcaa gattaatagt
    12421 cattcaaaat gtcgcctaaa gggtcaccag agttgcttcc gcctccatta tttgatgaac
    12481 cacccatttt agaaaggttc aagtaaataa gagctaatgc aacacctaaa gcacctagag
    12541 caatcaatgt taattgagaa attgcagcta caacgaaacc aataacgaag aatggccata
    12601 cttcttttgt agccatcatg ttgattacca aagcgtaacc tacagctacg accattcccc
    12661 caccgatagc cataccatct gttaaccatg ctggcattga ttcaaggaat gattgcacag
    12721 tttgtgctgg gataaatagc aacgctgctg ctgggaccgc gatacgaacc ccttgtaaac
    12781 atacagcaat gatgtgccac atttcaacct tacggatgtt tccttcttca gcagccgcat
    12841 ccatcaaatg aacgattgga acagcgattg tacgtacgat cattgttaag aacaaccctg
    12901 caacagccaa aggaacggca atcgcgatcg cagaaggaac acctttaaca ccttgtccac
    12961 ctaaaactaa aataattgct gatgctactg atgctaatgc agcatctggt gctacagcgg
    13021 caccgatatt tgcccaacct aaagcgatca tctgaagcgt accgccaagt acgataccag
    13081 cttcgaggtt accggtaact aaaccgatca atgtacatgc cactagtggt tgatgaaatt
    13141 gaaattcatc aagaatacct tccataccag ctagaaaggc aactaatacg actaaaatta
    13201 ttgaaataat agacatgata agcctcctat aaattttaat attatttatt acgcttttgc
    13261 taattcagct tttgcttttt tcaaaatatc atccatgtta tcgcgtgaat cattaggtac
    13321 tttacgtaca tcgaatttca cacctttttg ttcaagcttc tcaaacgctt caacgtcttc
    13381 ttgtcccata gacaatactt tacttacaac gactttaccg accgaatgcg ccattgaccc
    13441 aacatttaat tctttgatgt ctacgccacc ttcaacagct gtcaatacgt cttcaggatt
    13501 ttcaaataaa agcaatgctt tggtatttcc aaaacgaggg tcttttgcta cttcgatcat
    13561 tttgctaata ggaataacat ttgcttttac acctggagga gcagcttgtt cgattagtct
    13621 cttacgcaga tcatcctttg atactgcatc tgaaacaacg ataatacggt ttggttgcac
    13681 tgcttttgtc caagctgtcg caacttgtcc atgtaacaga cgtgagtcaa cacgtgctaa
    13741 tacatatttg atttttccgt ctccgaccac agttccttct ggaagtgctc ctttaggttg
    13801 tgcgtcttca actgctgctt tcggtgcttc tgccggttct aattcttccg gttttacttt
    13861 tacaccgtct tttgctgttt caatgatgtg tgctgcaatt tcatgagcag attccattga
    13921 aaagcgtgat gcgtaggctt caatcaacat tggtaaattc aaaccgctga cgattgccca
    13981 tttatctttg tgctcttcga ataatgtgtt tgattgattg aacggtgttc cgccccataa
    14041 atcaactaag aataacactt cgtcttgatt atcaaaagaa gcaaccgctt cttccaattt
    14101 ggctctcaag tcatctggac cttcacttgg tttcaaaatc acggctttga cgttttcttg
    14161 ttcgccaaag atcattgaac cggattgtaa gattccttca gcaaattgtc catgacttgc
    14221 taggataatc cctaccatat ttatacctcc tatttacttt tgttgtaaca aattcaaaaa
    14281 tattaataat tgctaaccat tacaacagaa ttatttgacc ttttccaaca accattcttg
    14341 ctacaccttt ttgattttcg ctagtagttc catcaaaagg attttcctgt cagcaggtac
    14401 ttttcgaatc tctaactcca cttcttgact gttcaagtaa cgaaaggaat caatatcttg
    14461 ttgatttact gaaacaaaat tggtaatcat tgatttgcct tcagtaaaac tcataccgcc
    14521 gatattcaac gacttcaact gtacaccgca gcggacaacc gcttcaacat cttggggatt
    14581 ggtgaataaa agcatcactt ttgctcgtga taataatcca ctatgataga tttgaatcat
    14641 tttctgcacg gttattacat ttgctgtgat ccccggcggt gcagcttctt ttagtagaaa
    14701 ctttctcaat ttatcttgag cgactacatc gctgatcaca atgatacgtt caacacctgt
    14761 ttgcttcgac caaactgttg cgacttgccc gtggattaaa cgatcatcta tacgtgccaa
    14821 tcgaatatcc atctgcaaaa ctccttcttc ctcactactt cacagaaacc cctatcattt
    14881 ctgtgtgaac aaccacctcc tagcacacac tactataagc aaaaagcgtg ccaacttttt
    14941 tacgatacac taattgaatt taaaggattc ttaaccaata cacaaaaacg atacactata
    15001 aaagtgtatc gtttttgtgt attcatggca cagtgtattc ttttttatct aactgattat
    15061 ggactagacg tagcagataa tacatttctt ctatcggcac ttttactttt atctgatctt
    15121 ccaacagaac aactgaggct gccaattggc tataaagagg atcattcgtt gtatttgtca
    15181 attcgttttc ttccacagtc aatggttcat tccgaataat acgttcgatc attcctgctg
    15241 tgtgcatcac taggttgatt ttgaatccat attcttcatc gccgattccc gtcgtctgag
    15301 agatttgtgt agaaaattgc cacattggat cgattaactt actaccatta ataaagatga
    15361 agttatcaga gataaactca acacacgtat ttttagctga ctcttcatct agggagatga
    15421 attcagtttc ctccaattct gattccatca gcaactgatc caaaatgact tcgatatttt
    15481 gatcaataaa acgttctaaa ggaataaatg gggcttggat attcaaatca gtaatcccag
    15541 tagtagctat gatctgatat tctttttgga taactggcag ttcttctttc acttccacaa
    15601 tcgacaaagc tagaacttct aattctgttt cttgacgctt gtttaccgct cgttcgatca
    15661 attctttgat tctttgtgct gtaccttcgc cagatgcgca gatagccaaa acagcttttt
    15721 tcttatgaat aggttttgct tcctgaacag attctacaga agatatttct gcgtaacctc
    15781 gaaaattttt caatgattca tgcaacatat ctagatctgt ccctaatact gagacctttc
    15841 gtacagtttc caaaactaga gaagttgtta ccatatcaac agtacgtact ggaattccag
    15901 tgtctctttg aatttgcgaa ttaaacgacg caagggaccc catatctact aagagtatga
    15961 ccccgcttcc ttcatctact tcttgtacat tgcgttcaat tcggtccaat gctgttttcg
    16021 gatccatatc caaaggcatg tctactgctc gtacgttctc tgcatctaac aactgttgga
    16081 caacttggac catactgctt gctgtgctgt ttccgtgagc tgcaacgact acaccgattc
    16141 tgccgcttgc ttgatttgcc cgtaacgaga cgagtagaac ggtcaagtaa tagtcttcac
    16201 tttctggaat ctccacttga aaatacgttt cgatataact acgcacttct ttcgcaacag
    16261 catattcatc tggaaaatca aaagccatct cacggatgtt atcattcgta tgccgttctt
    16321 ctcctaagtt gatttttttc aaaaaagaac tgatatgcaa gctcatagca taaataaagt
    16381 tttgctgaaa ctcatatggt aaagatcttt tgaccattac ataaatctga ttggtcactt
    16441 ctatgatttt cggatctaca aattctgcta atttgctgtc tgcattaaaa gaaaaaccat
    16501 ggtctttata gaaagacttc agatggatgt tgatatctgt agaaatgaaa tgattgattg
    16561 cttcttgatc caaaccatcc gacttcagta aagctgcttt atctccgatg atatcatata
    16621 gattataagg taactcatag gagtccgatt ggattttcat gatcgtatca tttggtgcta
    16681 cagttatctt tggctccaat attttagaaa gctctgccat tgcactgcgg ttgcttgcta
    16741 attgaatcaa tccgctacga atcccttctg tcaaatcatc gattgtgatc gagatttcgg
    16801 gtgattgcat atgatttaga aatcctcgtg cacatactaa ctggatattt gacttcaatt
    16861 gtcctatatt tccataggtc acactgccga tcaatgcttt tgctacatct tctgtcaaag
    16921 aaatctttcg ctgcgtgcgg tttgcttcgt gggcaatcat gatttttact aaatcgactt
    16981 tctcatttgc aggacgtttt tcaaaagccg gaagtttgat attgattggg atacgccgaa
    17041 caaaagtttc taatagagaa gaacctgggt cttctgtggt cgcacctacg atccgtacat
    17101 ttgcttcatg ggatttcgtt gtttccccaa gacgactgta agttccatga tccataaagt
    17161 aaaagatcat ttcttgacct tcaggcggca accggtgaat ctcatccaaa aacagcatac
    17221 cgccatccgc ttgatcgata atccccattt tttcttcatc tgcgcctgta aaagcacctt
    17281 ttgcgtaccc aaataaatga ctcatcaaaa gctcagggtt attggcataa tcagcacaat
    17341 tgaaaacaat cagttccgtt tcctcatcta ttacatgatg cgcttttgca aaatgataca
    17401 tcgcgtgtgc aaaataagtc tttcctgatc cggtaggtcc tgtaatcaaa caatttaatc
    17461 ctcttggcgg atacaaaatc gcagcttttg cctgttccac tgaatttttc atgctgccgt
    17521 tagctccaat gatttttgca aagatatcct tagtatctat ttggagtgta tttttttctt
    17581 cagagaccgg cgtttctttg taactgacta catgttttgt aactggcttt acgtgcgtaa
    17641 cgagtgtttg atatatgtaa cgtactggtc gtccgtctgt ctttatcagt tttccttcgc
    17701 gcactagctg attcagatct ttactgctat ttgttcgctg aatccctaac acttcagcaa
    17761 tttcctgtgt tgttactcct tgatcatatt ctgcctttgt taaatgagcg gttttttctt
    17821 tgacatacat ataaattcgg tcaatgcgtt ttgccaatgg tatcgctcct tttctataga
    17881 ctattgtact taggcttcaa aacataatac tatgtattta tttctgtttc gtcaactatt
    17941 tacctgattt tgttttgttg ataacacgcg gatagataga aatgttcaat ttaaaagaac
    18001 gaaaaatccc gatacgattt ttataatgga aacaagaaaa agaacactgt ttaccatata
    18061 attatttcac tgatagcaaa caatatagct tccatcaatt gaaaacgata gttatcaaaa
    18121 catcctgatt ccaaattggc aaaaaaatat taagtgtaaa aagacaaagt aaacttcgta
    18181 gcctccacta caacttttat t
//
LOCUS       DAFBSV010000058        17129 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.059, whole genome shotgun sequence.
ACCESSION   DAFBSV010000058 DAFBSV010000000
VERSION     DAFBSV010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17129
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.059"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(<1..188)
                     /locus_tag="LLB18_001861"
     CDS             complement(<1..188)
                     /locus_tag="LLB18_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244859.1"
                     /translation="MVHSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGNI
                     LTLNLTTKTFVDAAEDYP"
     gene            complement(325..660)
                     /locus_tag="LLB18_001862"
     CDS             complement(325..660)
                     /locus_tag="LLB18_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244860.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGNLVPYYTTWEMNEEGINNFPCKSI
                     KESISLTEC"
     gene            complement(681..2273)
                     /locus_tag="LLB18_001863"
     CDS             complement(681..2273)
                     /locus_tag="LLB18_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244861.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPDE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMGNGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQSEQKEYQRLNQAIKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWNYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKALKEEAKSLYGESKRESKNAEKNALFDLKKRTGNAILTELKRQDSQIKPLIEGVD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            complement(2292..2714)
                     /locus_tag="LLB18_001864"
     CDS             complement(2292..2714)
                     /locus_tag="LLB18_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244862.1"
                     /translation="MAKVIDKHIYFHQTHIDVLDEIISTHAEVKNYSEAVRFLCMNYD
                     PEVEKKVNSNQAKLNGMSKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKSNQTKKYSPQLKKPVNESVHARVDPFDPTKILKR"
     gene            complement(2716..3012)
                     /locus_tag="LLB18_001865"
     CDS             complement(2716..3012)
                     /locus_tag="LLB18_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244863.1"
                     /translation="MNVKIRDLDPKFISEIDRRCVELSNRTGNKWSRNDYLKLLIEND
                     FDRPLMEYKKEKFDQLLEKFSEIQSYNTKILEEYVSQNNRILEILIEQNRGSEL"
     gene            complement(3481..3711)
                     /locus_tag="LLB18_001866"
     CDS             complement(3481..3711)
                     /locus_tag="LLB18_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244864.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTAERK"
     gene            complement(3733..4539)
                     /locus_tag="LLB18_001867"
     CDS             complement(3733..4539)
                     /locus_tag="LLB18_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244865.1"
                     /translation="MSKKKGERQRFKKRKSYLQWLGIFMILGFLILASPIYTNQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQLKDQEEIIQKLQEKIDRMTKEKI"
     gene            complement(4550..5194)
                     /locus_tag="LLB18_001868"
     CDS             complement(4550..5194)
                     /locus_tag="LLB18_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244866.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQAANTYKIEEVAK
                     NASEKLKKNSSEAQANIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDNHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVVDFSYFTR"
     gene            complement(5210..6412)
                     /locus_tag="LLB18_001869"
     CDS             complement(5210..6412)
                     /locus_tag="LLB18_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBK5244867.1"
                     /translation="MENDTNIVMEHLKRRAKRRLFLWLFGTSAGLITILITVFVTLFL
                     ILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKL
                     LPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFP
                     NSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMSI
                     ITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGGE
                     FRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQ
                     EFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPL
                     PFLNSSKK"
     gene            complement(6486..6821)
                     /locus_tag="LLB18_001870"
     CDS             complement(6486..6821)
                     /locus_tag="LLB18_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBK5244868.1"
                     /translation="MKKNYHDLSQGDLVYIDLNPTKGHEQRGKRPCIILSKPNKYLNY
                     MIGVAPITTKAKPFPVHVDLNGTQKIKGQILLEHHRMIDIESRGFQFVEAVPKEILEE
                     CIEKIKLFY"
     gene            complement(6821..7084)
                     /locus_tag="LLB18_001871"
     CDS             complement(6821..7084)
                     /locus_tag="LLB18_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system, antitoxin component,
                     AbrB family protein"
                     /protein_id="HBK5244869.1"
                     /translation="MLVKEIEMKKWGNSQGIRFGKEELSVLGETNTENLKFEMVVTEG
                     KIVLTPKNKKPETLDELFANYEGEPLGKEDKYEWGNMQGREII"
     gene            complement(7143..7520)
                     /locus_tag="LLB18_001872"
                     /pseudo
     CDS             complement(7143..7520)
                     /locus_tag="LLB18_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            complement(7651..9528)
                     /gene="ltrA"
                     /locus_tag="LLB18_001873"
     CDS             complement(7651..9528)
                     /gene="ltrA"
                     /locus_tag="LLB18_001873"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBK5244870.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            complement(10216..11910)
                     /locus_tag="LLB18_001874"
     CDS             complement(10216..11910)
                     /locus_tag="LLB18_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBK5244871.1"
                     /translation="MLEAIKTAFSLQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTETQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLLKEKQMEEQDFKRFLAMIDECHNGATCSAVKSCGLQVV"
     gene            complement(12073..12666)
                     /locus_tag="LLB18_001875"
     CDS             complement(12073..12666)
                     /locus_tag="LLB18_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244872.1"
                     /translation="MRVKGQNSVDKKSILQFGKPEERSILDLFPYKSCTEEGVLVTKE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPIIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            complement(12667..12999)
                     /locus_tag="LLB18_001876"
     CDS             complement(12667..12999)
                     /locus_tag="LLB18_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244873.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            complement(13049..15421)
                     /locus_tag="LLB18_001877"
     CDS             complement(13049..15421)
                     /locus_tag="LLB18_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244874.1"
                     /translation="MIIGGIFSGIADWWSGLFGDGDADPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKIKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLENDPNKVEHIPTDKRNALTAKNFKTANINGIIT
                     PDQAKKMSESSDISTVQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYRRY
                     ISSPGIILAGESSLSVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSAIE
                     DISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQSV
                     TKIFGVDTSLKNGSNSLLSMFALGNVAKNVGSGAKNLASAGKSGLSNLNDIRKNGFGN
                     RKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGTAE
                     DLTEKAKDTLEEKLDGTRAKELAEAVKNPSETLEKQKEKASEIKEGLKDAYGEGQVNA
                     AVKANTTTEKENQEGAAIPSAKDHQDELHSNENSEEGQNGQLPKTDPEQYRYKSNINS
                     ENEKRISDLPKRNQEVQTDDDSIDLPNDNGIEVGTEKSTKIGLPKTQNLPMKDSRLNQ
                     FKENDQSFVHQSPAGTVQMKSSRLPENGNLTTVSYNLSESGETENASVQNIVTREAEP
                     KPIQNVHTGYKPANVAFTAPTKINVTRDTKNRNNALKEQLLRDIKQDIKP"
     gene            complement(15418..>17129)
                     /locus_tag="LLB18_001878"
     CDS             complement(15418..>17129)
                     /locus_tag="LLB18_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="HBK5244875.1"
                     /translation="YFNENAQKAVNALIFALLEQADQTGDYSKLTPNNLVELLSEIGG
                     FNYQDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNILSTAITGLNPF
                     TLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHQGKKFHEERVKVGY
                     RGFCEINFDCHLEQGDHVCLKYDHRGKEYVAWYEFSQRVLKDEEGNIVYRKKRGETHL
                     PELEKEAVLTLDEDKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHIIVSIFLSQLYK
                     ELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNMLWDLFIQSYQQL
                     YAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENSTINSLGMNTHI
                     NRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNHGETNLPYAYQY
                     IEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDIYARRLYHNMHDQIEEEAKEN
                     IFIKIVQSLDNSTAQKLLIQFYEEKQIDRLQEYLEKLRQNEEITEVIRKRLLLEAEKA
                     VKE"
BASE COUNT         4564 a         3537 c         2655 g         6373 t
ORIGIN      
        1 aatggataat cttctgctgc atcaacgaac gtcttcgtag tcagatttaa cgttaaaata
       61 ttgccacttt gataagcttt tgccgctttg tctgtgacga caaaagctct gcccgtttga
      121 atttctgtca caaaaacgag attatctctg cttttttcaa caacaactcc aatcgttgaa
      181 tgaaccattt cttcttcctc ccttctcttt cttttgatat aatgtagtcg caaatcgcac
      241 cactcaatga attggcggaa aacaattcat tgaaaaaaag aatcctggac aatcacgttc
      301 aggactcttt ttttcactta ataactaaca ctctgtgagt gaaatagact cttttatgct
      361 tttacatgga aagttattga ttccctcttc attcatttcc caagtagtat aataaggaac
      421 taaattccct tcatattctt gaatgataaa atatttttca cccttcacat gattacaaca
      481 atacacacca gtagctgggt actcaacgac taaaaattga tttggatcaa actgttcgtt
      541 tctcaacatt tctcttatct ggaacaaatg ctctttttct aaacaatcag gaagttgttc
      601 gattcgttct tctcttaatg atccttctat aactttccat tgatctaaat attgtttcat
      661 tgctattcct cctactgtct ttactgtctt tcttgttcca tttgaattct tcgttgttgc
      721 tcttcgtatg ctttacttgc gtggtatttt tcttcatggg cattaatcgt tcgatttaat
      781 tgacgcaaac tccgctgcgt gacaactctt tgttggaatt gtttcctgcg cttcatgaat
      841 tcttcgtaac tatatttgta ttcattcgtt ggcaattgtt taagcgttcg aaaggatcgt
      901 tcattgtaaa tagattgcat ctgatcgaca ccttctatta atggttttat ttgactatct
      961 tgtctcttca gttctgttag gatggcattt cctgtgcgct tttttaaatc aaagagggcg
     1021 tttttttctg cattctttga ttctctcttg ctttccccat aaagactttt tgcttcttct
     1081 ttcaatgctt ttgaaatctg tatatattct tggtattcag gttcttttgt taaaacatat
     1141 ttggttaact catcgagttt ctctcttgtg tatggtgaaa gtttggttcg tttttcatcc
     1201 ccgtaattcc attccgaacg tttgtcaggt agggttttat atacttcatt taataagttc
     1261 attgcgtgtc gatcgtaacg cgctggctct tttaccactt ttgttaaggt gttacgcaaa
     1321 tcacttttcc gagtcaataa atttcgtttt tccataccaa tcattcgatc cttttcataa
     1381 gaaaaacgtt ctaactcatg tacataattg gtcttcattg cgtctaatgt tgcttgtctt
     1441 ctcttacctt tcggtacgat ataactcaca ccattttcaa cctccgtgta aggtttacgc
     1501 gtattttctt tttcaacaac tgcaaaatga atatggatat gtttggtatt acggtgaatc
     1561 gttgccatcc agtagcctgt ttcgttcagt tgctctttct cgaataatgt ctccatcatt
     1621 tttcttccag ctgcttttaa tccttcttca tctaaagtat ctgttttggg atcgtacaat
     1681 cctatttttt caagatacga attatcatga gaaacaacat cttgataaat gattgagcct
     1741 ttttgttgcc ctctttggaa gatttgctta atctccttca gatcacttcc tttcacttcg
     1801 tctgaagcca tagaaaaaac tccagggaga tttcctgaag cttttttgtg tggctctgtt
     1861 tgatattttt ttattgcttg gttcaagcgt tggtattctt tttgttcact ttgcgtcagt
     1921 tctttctttt gttctaacgc atagtgacgg gtcatataag aaagatattt ggtaaaatct
     1981 tgttcctcta acttgtcaaa gttgattcca tttcccatca aagattgagc ttcattcgac
     2041 gtttcgctga attctttatc cgtcttactc tccgaaaaag tttctccttc aggaatataa
     2101 aaatcctcta aagcattctt gattcgttgc agttcctgtt cttcgtcggg cgtgcgtcgt
     2161 tccttttctt ccagcgcttt ttctcttgtc atataatcaa tgtatgttga aaaagatttt
     2221 ttattgggca aggtaaattg acaagtgaga atgactgcag gcgatttatt catcacgttc
     2281 tccttctact tttatctttt tagaatcttc gttggatcaa atggatctac tctggcatga
     2341 acagattcat tcacaggttt cttcaactga ggggaatatt ttttagtttg attagattta
     2401 attttccctt ccacacgttc ttttgcttct tggtaaaccg ttgaatttgt accaattagt
     2461 attcctgtat ctttcaaatg aagatctgca aactctgaaa ccatttcggt taaaatagaa
     2521 atttctttac tcattccatt caactttgct tgattggaat ttactttttt ctccacttct
     2581 ggatcatagt tcatacatag aaaccgaacg gcttcactat agtttttaac ctctgcatga
     2641 gtagaaatga tttcatccaa tacatcgata tgtgtttggt gaaagtaaat gtgtttgtct
     2701 ataacctttg ccatatcaaa gttcacttcc tctattttgc tcgatcaaga tttctaaaat
     2761 acgattgttt tggctaacat attcttctaa tatctttgtg ttatagcttt gaatttctga
     2821 aaacttttct aataactgat caaacttttc ttttttatat tccatcaaag gacgatcaaa
     2881 atcattttct attagtaatt ttaaataatc gttacgactc catttatttc ctgtacgatt
     2941 acttagttca acgcatcttc gatcaatttc agaaatgaat tttggatcta aatctctaat
     3001 tttaacattc ataaatatcc tccaatataa tataggatag tgaaaaggag cctatccttt
     3061 tcgctatcct acccctatcc ttttactatc ctttgctatc cttgtactat cctatatatt
     3121 ggtattttgg ggtcatttat ttttttcaga aacgtgatag gcacagccta tccaaccact
     3181 tttttttaaa agtggggtca cgtttcctta tgctctttaa aaattaaggt tatttgtgta
     3241 tttagacaat aaaaaatcct tctaactttg tcgattagaa ggaaatattt tgtcatatga
     3301 aaaatgaatt taagaaaaag tgtatgctat aattgatacg ctgtcttcct gtttggttga
     3361 aatcttcagc cagaaaggag gagtgttaaa tgttttatgt gcttgatgtt tgtgttacgg
     3421 tgatatagct gatccataaa catttttgat atactttttt cacataaaat cctcctgttt
     3481 ttatttcctt tcagccgtaa aatatttttt agcagctaca tatagagctt caaacgatct
     3541 gaattttaaa gtatctaaat tctttcgacc attcttcaac tcagatattg ttgtgttaga
     3601 taaattcact tctcgacata tttctttagc ttttacaact ttgagatagg ctttaatcaa
     3661 tactttttgc tcagcgaaag tatctttgtc agccaagttt gttcgcttca ttttttcact
     3721 ccacctgtcc ttctaaatct tttcttttgt catacgatca attttttctt gaagtttttg
     3781 aatgatctct tcttgatctt tcagttgcgt tttcgatgtt tcaatttctt gctggtagct
     3841 attaatcttg ttttcagtat tttcctgatc atctgcgact tgataaggca attgatcttt
     3901 tagcttcttc actaattctt cattcaaatc aatggttgct tggaaagatt ccatttgttt
     3961 ttgagctgct ttttgttctt tcttgtatcc tttcactttg taattgatcg cgtgttgttc
     4021 ataatcttca tctttcactt gatctttaac cttatcttcg tgcacgtaat aaatcagatc
     4081 ttgtggttct tgcatatcca cttttggatc aattttttca ggaataatgg ttaaacgcat
     4141 ggcgatatat tcttctggta catgcgttag cttcactgca aaataatcat cagacacctt
     4201 gatcactttg gctcgtattg cttgataatc ccctttagct gtctttactt ctacgcgata
     4261 attaagatta gccagttctt ttaacaagct ttgatcttca tcgtcgatcg caaattcaaa
     4321 aactaattgc tggttcgctc ctttttcttt tgaaaccatt gtcagctctt tcgtgtttaa
     4381 aaaggcgttc gtgcttacct catctggtat atctaccttc tgattcgtat aaatcggact
     4441 agcaagaatc aaaaagccga gaatcataaa gattcccagc cattgaagat aactttttcg
     4501 ttttttgaaa cgttgtcttt ctcctttttt cttactcatt ttcttcctcc taacgagtga
     4561 aataactaaa gtctacgact ttccattgac catctacttg tttttcagtg acagttaatc
     4621 caccttttat tttttgtggt ttgacatctt tgaattgcgg attgccgatt gtataatcaa
     4681 caaatacgac aaaattttgt tcctctttta cactgcttgt ttgagcgtaa gtttgcacgt
     4741 cacctaatgt aaaggagtaa cttccgtaat catcatgttg gtgattatcg tctgcaggac
     4801 ttaatttgtc gatcacttct tgggttgcga catcttttag tttttccgtt aattcatttc
     4861 tgcttaatga tttatcaatg gccaattgac cgaactcttc tgccgtcttt ctttgtgctt
     4921 cagttacttc ctcttttgct tttgtgccat cttgttgctt cagctgatcg atttcttggt
     4981 ttttctcatt gatggtttga tttaacttgt cgatgttcgc ctgtgcctca gaggaatttt
     5041 ttttgagctt ctcagacgcg tttttagcca cttcttcaat tttataggta tttgctgctt
     5101 gttcctcttt cagctgccaa aacaacgcaa tattgccgat taaactaacg ctaattgcag
     5161 ctgttaagac gatttttaac gttttatttt ccatattttt tctcctgatc tattttttac
     5221 tgctattcaa aaatggtaac ggatcgatcc atgtaccatc atcaatgaat gcatgtcctt
     5281 gtgcttgacg ccaatccatt cgagtaaatc ctaaatgcaa gtgtgctgta tctcgtatcc
     5341 caattacttg accaactttc acttgatcgc ctactttcac tcgagaattt cctgtactat
     5401 ttgcaaattc ttgatacacc atattcaagc catcgtaatt aatcacgatc acacacgcgc
     5461 ccaaacctga aataccagga ttgccaacgt acacgacttt tccgccatga accgcatgaa
     5521 tctcacttcc tggatgatca actgaaccaa aatctaatcc atcatggaag ccgttcggac
     5581 ggaattcacc gcctggattc gttccaaata attgaccacc gctgaaggaa cttttatcta
     5641 aactgctgcc agggaatgga ttcgtccatt caccagtaat tgtgccattg ttattgccac
     5701 cttcacccca atgtttgatg gcgaattcat catattcggt taatttatta gaagtgataa
     5761 ttgacataca acctgtataa tacggactat cttcagtaat tcctgcagcg gcataaccac
     5821 ctcgtcctaa gatcaataag cttgcgccag ggcttttatt tcctacacat gcattaaaat
     5881 ttgattgtgt ggctaccata aagccgtaat aggagaatgc agcttttgag ttgggaaact
     5941 tcatgtacca gcccccttca atgccaccaa ttcctcgtgc agttccttta ggaaacagac
     6001 aaccatcaaa ccaagtaatc ccaaaatagt tgagatcatt tcttgcggac gccgacgtac
     6061 caaacgctga ttcataaccg tattgcgaaa gaatcacact tggtaataat ttatatttca
     6121 ctgctgcacc tacggcatat tgcgcaatct catcagaaaa agggcctctt cctttgattt
     6181 ctttataaat cggtaagcct tccgaatact ctcctgtaaa agcttcgcca ccactacttg
     6241 aatcggaatc cgaattatca atcgaacccg ccgcaagtat tagaaaaagg gttacgaaca
     6301 cagtgatcaa aatagtaatc aaacctgcag aagtaccaaa caaccacaaa aataagcgtc
     6361 gctttgcacg acgcttcaaa tgttccataa ctatatttgt atcattttcc atatagtcag
     6421 tactcctaac tttttaattt taaacaacaa aaaagcgaag aaataataat tattcttcgc
     6481 tgcttttaat aaaataattt aattttttca atacattctt ctaaaatttc ctttggcaca
     6541 gcttccacaa actgaaaacc tctactctca atgtcaatca ttcgatggtg ttccaaaaga
     6601 atttgtcctt ttattttttg cgtaccattc aaatcaacat gtacaggaaa aggcttcgct
     6661 tttgttgtta tcggtgcgac accaatcata tagttcaaat atttattagg tttagataaa
     6721 ataatacatg gtcgttttcc ccgttgttca tgtcctttgg taggatttaa atcaatataa
     6781 acaagatctc cttgcgataa atcatgatag ttctttttca ttaaatgatc tccctacctt
     6841 gcatatttcc ccattcatat ttgtcttctt ttcctaaggg ttctccttca taattggcga
     6901 acaattcatc taaagtttct ggctttttat ttttaggagt taaaacaatt tttccttctg
     6961 ttaccaccat ttcgaatttt aaattttcag tattagtttc tcctagaact gacaattctt
     7021 cttttccaaa acgaatacct tgtgaatttc cccatttttt catttcgatt tcttttacta
     7081 acatggaatc cctccttctc tcacacatta gtatatactt gtatacacca aaatacaaga
     7141 agttactttc caccatcaaa caatttcaat tgacgtttgt tcggactaaa atgaacacga
     7201 atggtttctt ttgagccaaa attgatcaca gcgtctcctt gattttgttg aggaatggat
     7261 tctagttctg agttcgtcat tgatttacca actaatcctt ctatatgacg taaaatagat
     7321 tcatccatac gcataaagat cttcgtagaa gaaaattcaa agactttctt cagtttcgag
     7381 aagttatcag aagacatatt ttctggcacc atttcttgtg gggattgtgt agctaaaaca
     7441 gtcattgctt ctactttacg catttctcgt tgaaagtttg tgacataatt taccgtttca
     7501 ataaaatctg gattaatcga tactgatagg taagagtttg atattatctc cgtcttttcc
     7561 cccagtccac accgtacgtg cgactttcac cgcatacggc gttccctcgt ctataaaaga
     7621 cattctgttt tcccgtccta caaatattta ttaagatatt tcttcgttac caacttttaa
     7681 tctcaactca ttgagttttt ctttttgttt tggatttaat tttagatatt ttagaagttc
     7741 ctcaatcgtt tcactttgtg tagcgtgtat tacccgatga acctcctcag taacaatcac
     7801 taggttttca tagctatcac ttttgctttc atgataaggg ataatatgat gacaatgcat
     7861 ttcagataag ataagctcct cacctgttac tgcacatctt cccttttgag cgatgaattt
     7921 tgaaattcga ttgtccgcaa attcaatcgt tgctctctta ctaagcactg gattgctaca
     7981 caaccacgat atcttccatt cttctacggt ttgttgcttc ttatgaatgg cttccctacc
     8041 ttcttcggtg tatttattaa tatttctttt tttacacatc ggatgtctgt gttgaatata
     8101 ccctactggt aatattggaa accctcttat atatcgtatt tgtcctgacc gtaggtaagg
     8161 cttgtatcct tcgtactttc cgtattgtcc ttcttttgag attccttgtt ctcgtagtcg
     8221 tatttcaaaa cttggtctga gttctcttgc aatttttcgc attgctacac tacaatgagt
     8281 cgcaattttg aagtaattat gaatcccaat aaccatactg ttatagactc caatatagat
     8341 aaaggtatct ttgctattag gacttttttg aattcgtttg atttgttttt ttagtttcac
     8401 tttaatcatg ctttgtgctt ttgtacctat atgcgtatta acaacctttt tgttaccttt
     8461 ggtcactaat ttcatcgtaa agcctaaaaa ttcactttct tcttttgaaa gatttgtgat
     8521 ttttgacttt tcttcagata ttggtaactt tagacgctcc tgtaaccaca ttttagttgc
     8581 atagaaaact tttttcgctt cattataatt tctacagaaa attttaaaat catctgcgta
     8641 tctcactagg tatatttctt ttagagttgt actctttctg agcttgtgat agatattacc
     8701 tttatcccaa gctccatttt tcctaaaatg atgttttagc tctttggcat ctttttcctc
     8761 ccactgattt gctatccacc agtcaaattc gttgagattg atgttcgcaa gtaatgggct
     8821 aagtattccg ccttgtggtg ttccttttgt tgggtatatc aacttcccat ttggaagtac
     8881 tacgggtgct cttaacattt tcctaatgat taagagaagc tgtttgtctc gtatacccat
     8941 agaccagatt tgtctcatga gtttagtatg attgacttcg tcgaagaaac ctttgatatc
     9001 tacatctacc acatattcca tgtgactttg attcattcgg gccatacaat ctgctattgc
     9061 gtgttctgct gatctatttg ggcggaaacc atagctgtga ttattgaatt ttgcttcaca
     9121 tattggttct aatacttgta agatgcattg ctgcgcgatt ctatcccata ttgatggaat
     9181 acccaacggt cttaatttac cattatattt aggaatttct acacgcctta ctttccgagg
     9241 gttataatgt gcgaatcgct tcctaacaat ttctacgaat tcattacggt tgagattttc
     9301 aatatcttta atcgttactc catcttctcc tcttgtcaca ctaccgtgat ttctcttgat
     9361 attacgatat gctaggacaa tgttgttatc agaaatgata atctgcatta gattcttgaa
     9421 attatctccc ttcaaacttt tggagtatat cttatcgaag atttccgtca tgccataata
     9481 ttctgcatgc cgcaacttcc tatcttttgg acttgtttct tttgtcatgg tttatcacgc
     9541 tccaattggc tcgtgacctt tttagtcata cgagaatccc atggttgaac gggtttcatg
     9601 acttttacag acgaatcgag cctgttcctc cagttccatt acagaacctt catcagtcgt
     9661 gactctactt tcaccatcac taaagtaagt tatttgtcat tcacatattt cttactacca
     9721 cttcatcgag tatgcactct ccatgttgat ggcttcccct gttcccttat atctatccac
     9781 atgccttaac ttagatgcta gcttttgccc cctaacttct cctacgcctg taacgcagca
     9841 tggtctttca taacaacgac ttttactcaa ccacaagtta gcacaatgag tgattttttg
     9901 ctcactgtct ctcccatttc taggagctat gcctttcgga cagtacattc gctagttcgt
     9961 cagtacgttt gtacatactc accatattaa gtttttttgg acacccgact tatcggatac
    10021 accctttacc tctaaagaac tttcgtggta ttcactattt cttttacctt acggtatcct
    10081 tcagccgact tcaccgagct tcacacaacg ttggtctgca taaactactt gttgcatgtc
    10141 ggagtatcag tggaagccct ttgtggcgtt acccactcat ttgacttctc gttataagag
    10201 ttattacaat agtttttaga ctacttgcaa cccacagctt ttcactgcag aacaggtcgc
    10261 accattatgg cactcatcaa tcatcgccaa gaagcgtttg aagtcttgtt cttccatttg
    10321 tttttcttta agtaaacgtc gttgtcttct tccttgaatc aatgcctgat tccaaatcaa
    10381 cgtcatagcc atgtacattt gacattgttg tacccctcga tctaagcctg taatagagtc
    10441 aatgtcaaaa aagaccaact gttgttggtc aaggtgtcga atcgtactgt gaccatcaaa
    10501 aatcatgcca tacgtctcac ataaggattc tacgatggat tccatttctt cttttcgatt
    10561 ctttttctct tgggaagcac ctggtaattc cagttgtcct aaaaagtcta aaaattcttt
    10621 gaacgtcgga taagcttctg gatctttccc tgtgacttgc gtctcagtat ttgaacgcga
    10681 atttgaggaa gtaaagccgc gtggtactgt tccatactct tcataaaaac gatttaagta
    10741 ggtcttaaat tctgctttca tcgttccttt tagctgagga ctcactaact gtacctgata
    10801 gactactttg tctaagtgtg tttgatagga cgctgcttca ttgatcttca aatctttgac
    10861 tgatccatcg tcatataaac tggatgcttc atcatacgtc cgtgtggcaa atatttctaa
    10921 aggattgatc atcccgtcag acccgtctaa gcgcaccata atgccgttat attcctttaa
    10981 gaaggggata aagtctttcc ccttttcaaa gccccaaata aagtctcctg cagctaaatg
    11041 ggcttccgcg atcattttaa gaacggttga tttaccagct cccatcattc ctagaagcaa
    11101 ggtattagta gacaaccgca cactattttt atatgtcgca ttccagacaa atgggccacc
    11161 tgtcatggtt tccccatatt gagtccctcc tggatctttt agcgtttggt ggtggaacgg
    11221 gaatcctccg ccaatattta acgatggtag tgattgccct ttgatatttc caaaccattc
    11281 agcttgttca tcgaacatgg taaacatcga ttgccaatct cttttcgttt tgtgcagata
    11341 ggtcactgca cgataatcca tcccttttaa attttcaatc agttcctgcg ctcgttcatc
    11401 tacttcttga atcgtgtttc cgtaaacatg tactctcact ttgacttgct tagaaatttc
    11461 cccattagaa gtcaatttac gagcatattc cgctagttcc aggtattctt ctgcgctttt
    11521 atttcggtca gtcgcttttc gttcattatc tgatcgatca tttaattcat ctaaggcacg
    11581 attgatttga tcaatcactt tttgcttttc atctgtgcta acatcgagtg tggccactgt
    11641 atgaggattg ttcatgagat tggccaacca aaaaagcgta ggattttttg tgtagtgata
    11701 aactgtcaca catcgtgaat aaccattacc atacgtcaca tattcttcat caaaatttaa
    11761 cccaccttgt ggcatcactt gttttaaaaa atctaaatca taccctttgg atttcaaaat
    11821 ttctatttcc cgatttccta gttgctttaa tggatcaagt actttttgat cattttgtag
    11881 tgaaaaagct gttttaattg cttctaacat gtacagtcac ctcttcttgt ttgattcttt
    11941 acttggttaa aagattgccc ttttcccaac ttacccaggc ttaaagtgtg aggaaatttt
    12001 ctagtggtct cttccttcgg aacatctttt tctaaccata tcaatggata tttcattctc
    12061 tcttctccat tcctactcat cattcatatt gttcattcga tacagaatct tgatcaattc
    12121 ttttttgtag agtggtttta accctaaaat gccactagat cgcattaact gacggtttct
    12181 ggtttgtaaa tccttgattg tctttccttc aatgacgaaa aagaagctta agtcaggacg
    12241 ttcttgttct gctcgtttca attcctggat ttcttcgact aatttctttt catatttttt
    12301 taatcgttgt agatttcttc ctaaggattg ttccatacga ttcttatcta ataactgccg
    12361 cttttgcacg atttgttccg ttagatccgt ctctgtagtc aaactaacta acttaattat
    12421 tggcacatac gtacgcatga cggtggtcaa ctgattcatt cgttccagtt tctcttgttc
    12481 atttaatccc tccacgtcag tggaaacgac acgataataa cgttgaaaat gatcttcttt
    12541 agtaactaag actccctctt ctgtacagga tttataagga aataaatcca agatagatcg
    12601 ttcttctggt tttccaaact gcaaaataga tttcttatca actgaatttt gtcctttgac
    12661 tcgcatttat tcatcctcct tatacgtacc atgataattt cggttaggat ctaacgcatg
    12721 ataatggttc ttgtccgcaa aaaaaataga ctcgataatc gcaaaaattt gtcgttgacc
    12781 tgggttatta tagggtcgcc aaacaatcac taacgctatc gcaatccata agccataatt
    12841 caagagtgca aaaaagagtg gtaagtggac aagattattg accattttcg cccaaaaaaa
    12901 gcagccacca agcgttaata gatctaaaaa gaaaaaagcg aaaaacttcc attctccact
    12961 aaatcttgga gggtttttca tgtttatata tttatccata attgatttct ccttttcata
    13021 taaagaaaag gcctaacttg taggcctttt atggtttgat atcctgtttg atatccctca
    13081 atagttgttc tttcaatgca ttgttcctgt ttttggtatc tcttgtcaca tttatttttg
    13141 tcggtgcagt aaatgccaca tttgctggct tgtaacctgt atgaacgttt tgaataggtt
    13201 ttggttcagc ttctcttgtc acaatatttt gaacggacgc attctctgtc tcaccacttt
    13261 cagataaatt gtaagaaaca gttgtcaaat tcccattttc aggcaaacga cttgatttca
    13321 tttgaacagt acctgcaggt gattgatgaa caaagctttg atcattctct ttgaattgat
    13381 tcaaacgact atctttcatt ggtaaatttt gtgtcttagg caaaccaatt ttcgttgatt
    13441 tttcagttcc aacttcgatg ccattatcat ttggcagatc gatggaatca tcatccgttt
    13501 gtacttcttg atttcgtttt ggtaaatctg aaatgcgctt ttcattttca gaattaatgt
    13561 tagatttata acgatattgt tctggatctg tttttggtaa ttgaccattt tgtccttctt
    13621 ctgaattttc gttagaatgc aactcatctt ggtgatcttt ggctgaagga atcgctgcac
    13681 cttcttgatt ttctttttcg gttgttgtat tagcttttac tgctgcattg acttgtcctt
    13741 caccatacgc atcttttagt ccttctttga tttctgaagc tttttctttt tgtttttcta
    13801 gtgtttcgga tggattcttc acagcttcag ccaattcttt agctctcgtg ccgtctaatt
    13861 tctcttctaa ggtgtctttg gctttttctg taagatcttc agctgttcct tttaacccac
    13921 gttcattgac gtaaccaaga ccttctgcgg ctttagaaac accatttttc gctttcccga
    13981 acatttcgga aactgttttc ttactattag gtacagttgt agctttatcg tctgattgtt
    14041 cttccccgtt atcaggggta acatcttttc gattaccaaa tccattttta cgaatatcat
    14101 ttaaattgct taaaccactc ttaccagcac ttgcaaggtt tttagccccg ctacccacat
    14161 ttttcgcaac atttcctaag gcaaacatgc taagaagaga attgctgccg tttttcagac
    14221 tcgtatcaac gccgaaaatt ttcgtaactg attgagagcc tttgaatagc gcaatggtta
    14281 atacaattaa agcgacaaca tacaagaatc cattgatctt tcctgccgca tgcaaatcac
    14341 cgatacctga aagcattaat gtatagattc gtaattctaa aatcgtaaat gccaataaca
    14401 agaaggattg agaaatatct tctatagcac ttttcatccg ttgtcctgtc tcaaagtccg
    14461 ttgacgcggc aatcactaaa tagaattttt taaataccag ctcaataatg caagtaacaa
    14521 tcgtaaacaa gataaataaa taggctaccg acaaagaaga ttcaccagct aaaataatac
    14581 ctggactact aatgtatcgg cgatagcctg aagtatacac atattttgct aaaccttcat
    14641 cactaatttg aacagggatt tctttcccat tatcgtctaa ctctagtcga tactgtaatg
    14701 cctttaaccg atctttttgt actgtactaa tatcacttga ttcagacatt ttcttagctt
    14761 gatcaggtgt aataatccca ttgatattcg ctgttttaaa atttttcgcc gtgagagcat
    14821 ttcttttgtc tgttggtatg tgttctactt tgttcggatc attttctagt aacgtactca
    14881 catcaatcac attattttga ataatttgaa aagcaggtga accagtttta tctgctttat
    14941 ttgctgcagt cacgtctccg taaaagtttt tactaatatt tagcccttca tcgattaaag
    15001 aactaccacc aaaaatcaaa atcatggcca taaatagatt aaccaagata tttttgattt
    15061 ttggtggatg tttactcata aaaaatttta agcctaaata aattaatgtg acgacacaaa
    15121 aaagagccaa taccttacta atcaaacttt gaaacagttc attaacacca gcggcgttca
    15181 ataagtcttt taaatcaaag ctttgataaa ttgttttttc tagtaaagta ttgagattat
    15241 ataacccttt aatcaaaccc cataaaaaag tattacaaat ccaactgaat acatcttgat
    15301 actgcagata attaccataa tcttgtaaga ctttcgttac ggttttggga tctgcatccc
    15361 catccccaaa taagcctgac caccagtcgg caatgccgga aaatattcct ccaatgatca
    15421 ttctttcacc gccttttcag cttctagcaa aagtcgtttc cttataacct ctgtaatttc
    15481 ttcattttga cgcaattttt caaggtattc ttgcaaacga tctatttgct tctcttcata
    15541 aaattgaata agtaactttt gtgccgttga gttgtctaaa gattgaacga ttttaataaa
    15601 aatgttttct ttagcttcct cttctatttg atcgtgcata ttgtgataaa gtcgacgtgc
    15661 atagatatca ggtagaaaat aatcgtaatc aatttgtaaa gccttaagat ccaagtccgc
    15721 atgtgtacaa tgtatgtcta tatcattgat atcccacgat ggattgaaat cttcaatata
    15781 ttgataagca taaggaagat tcgtttcccc atgattaaaa ataggatacg gccgtatttt
    15841 atgacctttc aaatcttgtc gttttaaagg agcgagtaca atcgtttcac cttctaaaaa
    15901 agtagaaatt ctttcaggag ttaagatgcg atctgaatca acattgcgat tgatatgagt
    15961 attcatacct aatgaattga tggtactgtt ctcttgttca accgtcttat tccccacttt
    16021 tttggaaaat tcttctatgg tattatcgtc tgtcgacata atataaatat gtgtctgaca
    16081 attttctttg ataatcgctg cgttttgttc cccatacttc gcataaagtt gctgatagga
    16141 ttggataaac aaatcccaca acatgtttct accagctgtg actgtcatga ttccttccat
    16201 attatccatt ggtggcatat tcccaaattc atctaaaata aaatgaatcc tacggtgaca
    16261 tttatctcct ttagtcttaa cacattgcgt agataattct ttatacaact gactaagaaa
    16321 aatactaaca atgatatggt tagatggatc ataatcaggt gtgagcataa aaatagccat
    16381 tggtttatcg gtatagtgca tccgaataga ctctactaat aagttacttt tatcctcatc
    16441 taatgttaga acggcttctt tttctaattc tggcaaatgg gtttctcctc gtttttttcg
    16501 ataaacgata tttccctctt cgtctttcaa tactctttga gaaaactcat accaagcaac
    16561 atattctttt cctcgatgat cgtattttaa gcaaacatga tctccctgtt ctaaatgaca
    16621 atcaaagtta atttcacaaa aacctctata gcctactttg acacgttcct catgaaattt
    16681 ttttccttga tgataaaact ctacaacaat tcgctggttt aacagactct cgtgtagttt
    16741 gagatccaaa tacttcggaa aaccaatgga cttataatca atggttgatt gagaagtcat
    16801 tttcgcaatt ttcgtcagtg taaatggatt tagtcctgtg atcgctgtcg atagaatgtt
    16861 gcctttcgct ttatcagaac caatttttgt tgccccatat tgtttttttg ctatgtttcc
    16921 aggtggtaac tgattcataa attcatctaa agcattgagc tgcttgaatt cattatcagg
    16981 atcttggtaa ttaaaaccac caatctcaga aagaagttcg acgagattat tcggtgttaa
    17041 tttggagtaa tcccctgtct gatccgcttg ttccaataac gcaaaaataa gcgcattgac
    17101 agctttttgc gcattttcgt taaagtatt
//
LOCUS       DAFBSV010000059        17106 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.060, whole genome shotgun sequence.
ACCESSION   DAFBSV010000059 DAFBSV010000000
VERSION     DAFBSV010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17106
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.060"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            7..1398
                     /locus_tag="LLB18_001879"
     CDS             7..1398
                     /locus_tag="LLB18_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBK5244876.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIETSGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            1414..2454
                     /locus_tag="LLB18_001880"
     CDS             1414..2454
                     /locus_tag="LLB18_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBK5244877.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            2473..3558
                     /locus_tag="LLB18_001881"
     CDS             2473..3558
                     /locus_tag="LLB18_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HBK5244878.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            3591..4553
                     /locus_tag="LLB18_001882"
     CDS             3591..4553
                     /locus_tag="LLB18_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBK5244879.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            4546..5979
                     /locus_tag="LLB18_001883"
     CDS             4546..5979
                     /locus_tag="LLB18_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HBK5244880.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKGELI"
     gene            5976..7046
                     /locus_tag="LLB18_001884"
     CDS             5976..7046
                     /locus_tag="LLB18_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244881.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            7033..8454
                     /locus_tag="LLB18_001885"
     CDS             7033..8454
                     /locus_tag="LLB18_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBK5244882.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            8467..9474
                     /locus_tag="LLB18_001886"
     CDS             8467..9474
                     /locus_tag="LLB18_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBK5244883.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            9486..10490
                     /gene="neuB"
                     /locus_tag="LLB18_001887"
     CDS             9486..10490
                     /gene="neuB"
                     /locus_tag="LLB18_001887"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HBK5244884.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            10487..11635
                     /gene="neuC"
                     /locus_tag="LLB18_001888"
     CDS             10487..11635
                     /gene="neuC"
                     /locus_tag="LLB18_001888"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HBK5244885.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            11608..12285
                     /locus_tag="LLB18_001889"
     CDS             11608..12285
                     /locus_tag="LLB18_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBK5244886.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            12275..13417
                     /locus_tag="LLB18_001890"
     CDS             12275..13417
                     /locus_tag="LLB18_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBK5244887.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            13430..14407
                     /locus_tag="LLB18_001891"
     CDS             13430..14407
                     /locus_tag="LLB18_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBK5244888.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            14407..15315
                     /locus_tag="LLB18_001892"
     CDS             14407..15315
                     /locus_tag="LLB18_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HBK5244889.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            15316..16068
                     /locus_tag="LLB18_001893"
     CDS             15316..16068
                     /locus_tag="LLB18_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HBK5244890.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            16073..17020
                     /locus_tag="LLB18_001894"
     CDS             16073..17020
                     /locus_tag="LLB18_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HBK5244891.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT         6163 a         2190 c         3090 g         5663 t
ORIGIN      
        1 gtatatatga ataaaaatgg agaatggagt gctgcacgac ggatattcat tatattaatg
       61 gatgttattg tatacaatgc agcaatatat agtagtttct tactgaagtt tcgtggagag
      121 atcccattac gaaatttaga aactttccaa cactcagcaa ttattatttc agtgattttt
      181 attgcgttga acattttgtt gggtgcatat gttttttata atcgaatgat cagtgacatc
      241 gtgtttgtca cagtcatcgg tcaggtattg atgacactag ggatcatggt agtgactttt
      301 gcgggccgct ggtttgcttt tccacgtctt gttatcttac tttcatttgt tctcggtacg
      361 cttttcttaa gtatctatcg tattctcgta tataaacttt atttacgcgt aagtcgagat
      421 aaaaaggtcg tcattattgg gttagaaaag gatgtcgcac cagcaatcca aaattttggt
      481 tcaaagaaaa acaacaaaca taaagtcgaa gcagtcattc ttgataacta ttatgcaaac
      541 atcaaaaata tgattaaaga catcgatatt gtctatcttg cttctcatat cgaagaaact
      601 gaaaaaatca aaatctatca attagttact aaaaatgaaa aaaaattgtt tttgaataca
      661 acatttgaaa acttgacatt gatcaatcca aatattatga atttcgaaga tgaaagtatt
      721 attgaaacat ctggatttag aatccaacct gaatatgaac tattcaaacg tttgtttgat
      781 atcatcgttt cacttgtttt attagttatt gcttcaccat ttatgttatt cacagcaatt
      841 ttagtcaaag tgacatcacc gggaccaatc atctataaac aagtgcggat cacaaaaaat
      901 caaaaggaat tttcaatcta taaattccgc tcgatgaccg ccacagccga agcaaaatct
      961 ggaccagttt tagctaagag caatgatgca cgagtaacgc ctgtaggtaa atttattcga
     1021 gctgtccgct ttgatgaatt accacaaatc ttcaatgtgc tgaaaggcga tatgtcgatc
     1081 gtaggaccac gtcctgaacg tcctttcttc gtcgatcagt tcaatgcaga aaacccttat
     1141 tactacttac ggcataatgt tcgtgctggt atcactgggt atgcacaagt ctatggaaaa
     1201 tatgtctctg attacaacag taaattacgt tttgatttac tttatatcaa aaaatattca
     1261 ttgatgcttg atttaaagat cttgctgcaa accatcaaga tcctatttga taaaatgtcc
     1321 tctcaaggac ttgaagaaga cgaaaatgtg atctcattgg cagaaattgc ttttccgaat
     1381 gaaaaaatct ttcgctagtt gggaggcgta aaaatgaaca atccgaaatt cagcataatc
     1441 gtaccagtat acaatgcaga agcaactatt ggtcgaacga ttgatattct aaaagaattg
     1501 gattatgaag agtacgaagt cgttttagta aatgatggat caacagatca aacacaggaa
     1561 atcattcaag aactgattga aaatgatgaa cgttttgaat tgattactac gaccaatcaa
     1621 gggcccggat tagcaagaaa cgaaggaata agacagtcaa aaggagaata tctcttattc
     1681 ttcgatgcag atgacacgcc agtaaaaacg atcttgtcag attatgatca tttgctagaa
     1741 aagagtccaa aagcggatct tgttgttagt tcgtttgttt ttcgtacaat ggacgaggga
     1801 agaatcgttt ccgaaaaaga aaacttagtt acagaatgtc actatctaac tcacgaagag
     1861 tttataaaag acatgtatca gttaatgaat gaacagttga tgtatgttgt atggaacaaa
     1921 tgctatcgta gcgatattct gaaaaataac caaattctat ttaaaactta taatagttgt
     1981 gaggatcgaa tatttaactt acattattat gaatactgtc atcaagtgat catgaaccca
     2041 aaagtagaat atatttatga atttgaaggt gggaagggga tcactaatca ataccgacct
     2101 aacaagttcg aaacatttaa agaattctat tcattagcaa atactgtaac agacgatatt
     2161 aataaagacg gtatggcggc gcttctttta aaagggacaa cttcagttat tttttctatt
     2221 tatagtacct ctgcaagaac ttcaaaagag aagaaagacg aagcaaagca gatattgagt
     2281 gatccagtga tccgagaagc caagcaaatt gctaagacgg attcttcagc aaaaaaaata
     2341 acaaagttgc tttacaatat gccagctcca ctatttttat ctgctgtaaa agttggaagc
     2401 ttcgttgaag tgaaaatgcc agggttaatg gctgctttga agcgagtata ttagttaatg
     2461 gaggaaaata taatgaaaag aattttgcat tttcagggac gaatgggttt aggtggagca
     2521 gagtctttca tgatgaattt atatcgtaaa attgatcgta caaactatca atttgatttt
     2581 ttgatttatg aagattatgc agatgttcaa gactatcatt cagagattga aagattagga
     2641 ggccgtattt ttgttgtacc taatcctaag aaaaatattt ttaaatattt aatagaagtg
     2701 aataagttac taaaaaaaga atctttttct atagttcaca atcaggttta ttttggcggg
     2761 ggaattaatt tatggttagc caaaaagaat ggaatcagac agagaattgc tcatagccat
     2821 gcaactgaag atggaaaatc tcaaaatatt gtaatgaatg tattgcgtaa atttttaacc
     2881 aaattgttgt tacaaaatgc aacagactac cttgccgtta gtcaagaagc tggtgaaagt
     2941 ctgtttcaaa accatccctt tgagatagtt cataatggta ttgatttaga gctttatagt
     3001 aaaaattcag aagctaaggt taataagaga aaagaattgg atatctcaat gagtactttt
     3061 gttgtgggaa acattggacg attagagaaa caaaaaaatc aatcttattt gttagagatt
     3121 tttttagaaa tactaaaaat gaattctgat tcttacttga ttttagtagg tgaagggtca
     3181 cttagaaata aactgaaagc caaagcagta gaattggata tagagaaaag agtaaaattt
     3241 ttaggagaaa gaaacgatat tcccgagtta ttatctgtga tggatgtttt tgtaatgcct
     3301 tctctttatg aaggtctgcc aatggttgga ttagaagcac aagcagcaaa attaaaatta
     3361 gtcttagcag atactatttc caaagataca aagttaacaa ataatgtgga ttttgtatca
     3421 ttagatgaaa caccacaaga atgggcaaaa aaagtaataa aagagccgta tgctaataaa
     3481 ataacacaag aactaaagag ttatgatgtt tcgtacacta ctgaacaaat ggagagtata
     3541 tatagtagag atcattaaaa atgttcaaga tattttagga gtgattattt ttgaaaatat
     3601 gttatttgat attggcatac aatgatattg gcaacttaaa gagattggtc aatcgattga
     3661 acgaaaatgc agtttttatt attcatatag ataaaaaaac tgatatagaa ccatttattg
     3721 aagcatttaa atcatatgat aatgttgaat ttttatgtaa taaaaaccgt gttaaaattt
     3781 attggggtgg tttttccatt gtacaagcag aaatcaattt agtaaagaga gcattacaaa
     3841 atgagaaata tttaaaatat gtattattat ctggtgctga ttatccaatc aaagataatg
     3901 agtatattta taattatttt aaaaagaata gttcagtgga gtttattcgt ggaatagatc
     3961 tagatcaaat taaacataaa gaattttatt ataaacatat agatgtatat caaaaacatg
     4021 attatcctag aattaatagg aataacacaa ctgcatttaa aatttttaga gctataatta
     4081 atcgttgtct gaggatgatt aaacttcccc caaaaattag acaccataaa tttgatttgt
     4141 atcatggttc tcaatggtgg gctttgtcga aagaatgcct aacagaatta atacaaatgt
     4201 atgaacaaaa tcaacaagac tacctgaatt ttaaaatagg tatgtttgcc ccagatgaaa
     4261 aattttttca tacacttttt tttaattcct cgttcaaaaa taaaaatgtt attggaggac
     4321 cagatttacc acttgaattg aaaaatattg aagaaactac tttacaaact tcgaaattag
     4381 caaatattca tattattgat ccttccatga acaaatggtt tgatgaaagg gatatagatc
     4441 aaataaaaga aagtgaaaaa ttatttgtaa gaaaagttaa atcggattac tctgataaac
     4501 tattaaatag aattgataaa gaaattttga aagttggaaa tatagatgaa tagaatagta
     4561 cctgttttag agaagagttt attaagtcga gatgcgtttc gagtaataaa tttaatcatt
     4621 tgtctgcttt attttatgcc tagtactttt aatgtaacta atatcccgat gaaaatagct
     4681 tttgcttggg gtggaattat agttttgtat gaggttttta taaagaaaaa tttttttaaa
     4741 atgcgttttt cttggctact gattggagca atgattagtt ttatcttaac tataatcatt
     4801 aacagagaaa attttttaat tccatctatt tataattttg gatatttgct gattactttg
     4861 atagtaattt ttcctgcaga cttttcacaa agtgaagagg aaaaaaagaa aaaaatggtg
     4921 tattttaata atgttttcat tatcataatt tttttagctg cgctaatatc tatctatcaa
     4981 tttatttttt tgatttctta tcatgtccca acaggaacgc caggattact tgcaagacaa
     5041 ggttttattg aacatcggtt atttggtgtc tatacaagtc caaatgttgg agctatgttt
     5101 ggatatactt ctattatttt aagtttaatt agtgtattaa tttcaaaaat aacaaaaacg
     5161 attcgtgttt tttatatgat gaattttatc gtacaaatat tttatattac actttcttcg
     5221 tctagaggtg cccaggtagt aatttgttct tttttagtat tatttctttt gttgtttgcc
     5281 aattcaaaat ttagaaagag cattagagaa gtactacctg taaaaatcaa atggatggta
     5341 agcatattat tagttctatt ggtatatttt tcttttggta ctaattatgc taaggatttt
     5401 ttagcaacaa ttcctgtatc gattgataga aaagtagaag ttatagagtc aaatgaatca
     5461 gataaaactc cacttccaga aaaagaagta atattacagc attctagtga taactccgaa
     5521 atttcagctg gtcgttttac gatttggaaa gctgcgctta aagttataag accaactttg
     5581 ttatttggtt atggagagac cgatttctat gggaatagcg atgcaaaatt tttgaaaaaa
     5641 gtagatcttg atactacaga tgtgaatgaa ctaaaaagag cacatggaaa catgcataat
     5701 ggatttcttc aagtacttgt atcaagtggt ataattgctt ttatatgtat ctatgctttc
     5761 tatgtgttaa atatctttag tttactcaaa acatttttta gaagtaaagt gaattatgcg
     5821 tttcttggta ttgttttaat ttttatacta tctattttta tagatgaaat ggtggaggct
     5881 catgtacttt tcaataagcg cgatgtcatt tcaattgttt tctggtatta tttgggaagc
     5941 atttcttact tgtatttaaa aaaaggagaa ttaatatgaa gacagctttc attgcttgga
     6001 ctcctttaca tttgattaat atattaaatg tttatcaaaa tttttaccga gaatcaaaag
     6061 gagatttatt tatttattct gaatttgaaa acgctagaag atatagtgag cgtataaaag
     6121 aattagggct atttaatgat gttgtttttg tgaatcaccg gaaaatcggt tcttccttta
     6181 aacgtaaaat taacttgtta actaaccata atcaattttt ctcggatgat ttatccgttt
     6241 atgatgaaat ttttatacag ggggaaaatt atttcacaaa aatacttttc tccaatgttt
     6301 acaaaaaaaa tccagatgta aaactaaatt atatagaaga tggtttgggt acttatttga
     6361 agaagagtat attttcaaca agtaaaaacg ttcaaagagt ttttaaaata ttaaataaaa
     6421 atagcatctt caaaaaaaaa attgacgatt attttgtcta ttgtccggaa ttgttacttt
     6481 atgatgtaaa aaatataaaa aaaattccca aaatagatga aaacagtaaa ttgatgaaaa
     6541 acatacaatc aatctttggg atagaagaag tttttgtcgg agataaatgt atcttttttg
     6601 atcaaccttt attatctgat ggttatggca tagatgaaac agatattttc gctaaagtaa
     6661 atagtatatt ttctggaaaa aaagaaactt taattaagct tcatcctaga gcaaggacaa
     6721 atcgttatgg tgaaaaaaac atattgaatt ccagtttacc gtttgaagtc ttgctacttg
     6781 aaaatgactt ctcttcaaca cttttgatta gtcctatatc tacaatttct ttttcaccat
     6841 ctatgatgtt tgaaaagacg atcaactcta ttatgttggc taaattaatt ttaaatgaat
     6901 atacagcatt atctgaagat aaaaaagaaa cattgacaaa tattgttctt ttctgtgaac
     6961 attataaccg tctatcagaa gaaaaaattt tactcccaga aaactgggca gaattaagaa
     7021 agttggtaga gtatgggatt atttaacaca ctttccaagt caaaattagt taagtccagt
     7081 ttctggtata ctatagggaa tttttttatt aagggaattt cattcataac tattcctatt
     7141 tttgtaaata ttactactca agcagaatat ggtttgatta ataatttcac ttcatttgta
     7201 tcaatttttt cgattcttgt tgggctaagc ctaaattcgg caattaataa tgcaagtttt
     7261 gactataaag atgacataaa tgaatttatg tcatcggtac tttctctagc tacactttcg
     7321 ttaattgtgt tcttattaat agggaacata tattttttgt tttcaaatgc tttttttgat
     7381 atgaaccaac ttgtatttaa tttgatgtta ttacaaagtt ttgctagttt tgtaattagt
     7441 tatatccagt cttattttac gattaacttt aaccatttta aatatttgat tttatctttt
     7501 atatctactt ttttgaatat tgcaatctct gtagctttga tgcagacatt atattttgat
     7561 gataaatatg ttggcagagt agtcggcgga acactgtcat ttgtgttgat aggtttagta
     7621 atttatttaa gaataatgat aaagggtgct catttttttg ataaaaaaca gtggagatac
     7681 gctttaaaaa tctctttgcc gctaatccca cattccttag caaatatagt tttagcacaa
     7741 ttcgatagaa ttatgattaa ttcttattta ggtcctgctg cggggggaat atattcctac
     7801 attagtaaca taggtattat tctaagcgta atatggatgt ctactaataa cgcctgggtt
     7861 ccatggttct atggtgagat gagtaaaaat aatgaaaaaa aagtgaagaa agttagtaac
     7921 tattatttag tagtctttac tttgattacg atgattgtaa tggtagtttc gattgattta
     7981 gcaaaattta tggctccgaa agactattat tctgggttat ctttagtggt tccgataacc
     8041 ttaggctatt tctttcagtt tttatatagt ttaccagtta atgctgaatt ttatgagaaa
     8101 aaaacatcgt ttattgcgat tggtacagta gcaagtgcta tagttaatat actattaaac
     8161 atgattttca tacctaggtt aggaataatt gctgctggat acacaaccgt atttacgtat
     8221 tttttacttt ttatttttca ttataatatc gctaaaaaaa ttacgaataa acaattattt
     8281 gacacaaaaa aaatatgtat cataataatt tttgtatcaa ttttttcttt gatacttcat
     8341 attttaatca atcaaatgtt gattcgttac gttttgacat cattattgat aattagttta
     8401 gttatatatt ttttaaagat taagaatcga attatagatg actataattc ataggaggag
     8461 atataagtgt ttaaaggaaa aacaatatta gtaactggcg gaactggttc cattggaagt
     8521 gaaattgttc gtcagctttt aaaatatgaa ccaaaagcta tcagaattta tagtagaggt
     8581 gaagaaaaac aattttatat gcaacaagag ctctcaaatc acactaattt gagattttta
     8641 attggtgata tcagagactc tcaaaggatt gattatgcat gtcgtgatgt ggatattatt
     8701 tttcatgctg ccgcaatgaa acacgttcca gcaagtgaat ataatcctat ggaagctgta
     8761 aaaacaaatg tgatgggaac tcaaaatgta atagatgcag cgatcaaaaa taatgtaaaa
     8821 cattttgtag gtatcagtac agataaagta gtgagtccta ctaacaccat gggtgcgaca
     8881 aagttattga gtgaaaaatt aataatagct gccaatcagt ataaaggaaa aacagaaaca
     8941 atattttctt gtgtaaggtt tggaaatgtc atggggtcaa gtggatctgt tattcctctt
     9001 tttagtaaac aaataaaaaa caataaagat attactttga cagatgttga tatgacacga
     9061 tttatgatgt caataccgga tgctgcaaga ttagttctgt ctgctgctat gaattcaaaa
     9121 tttggagaaa catatgtctt aaaaatgccg gcaatcaata ttttaacttt agctcaatca
     9181 ttaataaaaa tatataatga tacacatgat gaaaaatata gaggtgaaat aaaagttgta
     9241 ggtatcaggc caggagaaaa attatatgaa gagctaatga ctacagacga aattgaacgc
     9301 tcatatgaaa atgataaaat gtatatcatt ccaccacact atcatgctac tgacgaactg
     9361 tacaaagatt atgaaaaaat taaaatcact gcatactctt cagatgcaac agaattaatg
     9421 agtggacagg aatttattag aatcgcaaaa gagaataatg tcgtgacttg gtaaggagtt
     9481 ttatgatgaa atcagaagta tatgtaattg cagaaattgg tgtaaaccat aatggaagtc
     9541 tagatttagc tttagaaagt attgataaag ctaaagaatg tggagctaac gcggttaaat
     9601 ttcaaacatt taaaacgaat aagctagttt ccaaaaaggc tccaatggca aaatatcaga
     9661 aggataatct taaagaggac agttctcaat ttgaaatgct aaaaaaatta gaattatctc
     9721 aatctgattt tattagaata aaagattatt gtatacaaaa taaaattgat tttttgtcta
     9781 ctccttttga tgaagaaagt gcagactttc taaaacaaat tggtgtacaa ggatttaaaa
     9841 ttggctcagg agatttaaca aatttacctt ttcttagaaa aatagatatg tatgggttgc
     9901 cagttttatt atctacaggt atggctgata ttcatgaggt cagtgaggct gtagattgtt
     9961 tcatagatag tccagttact attttacatt gtacttcaaa ttatccggct agttctgaag
    10021 atattaattt attggcgatt aacacattaa aagaaatgtt cgggataccc gttgggtact
    10081 ccgatcattc attgggatat gatgttggta tttgtgctgt tgcgatgggt gctaaggtaa
    10141 ttgagaaaca ttttaccttg gataaggaac tacctggtcc agatcataaa gcttctttag
    10201 atcctcagga atttgcagat tttgtaaagc atattagaaa cactgaaata tttttaggtg
    10261 atggtgttaa gcgagcaatg ccttctgaac ttagtacaaa agaagtatca agaaaaagcc
    10321 tagtggtcac tgagaattta aatgtgggag atattcttac agagaaatct cttacaataa
    10381 aacgtcctgg aaatggaata gctcctaagt ttttatatca atatattggc aaaaaagtta
    10441 aaagaccaat aagtgcagat agtgttctgc ttgaggaaga tgttgaatga aaaaaatact
    10501 tatagtaagt ggaacacgag ctgattatgg aatatataaa cctgttgctg agaatttact
    10561 acaagataat tgggatgtat catttgttgt ttctggaatg catttatccc ataaatatgg
    10621 atttactaaa gaattgatct tagctgacgg atttagaatt agtggagaag ttcaaagttt
    10681 gtttttagag aacaataagg gaaacatggc tcggtctgtg gcattagaga taaatggttt
    10741 cacaaatata tttgaacaaa ctagccctga ttttgtatta ttactagggg atagaggaga
    10801 aatgttggca gctgcgatag cttgtttgta tcttggaatc aaaacagcac atattcacgg
    10861 aggcgaagtg tctggtactg tagatgaatc aataagacat gccataacga aaatagcatc
    10921 tgttcatttt gctgctacgg aaaaaagcaa agagcgttta ataaaaatgg gggaagattc
    10981 ttggagagtt tttcccgtcg gagctcctag aatagatact attttaaata atagattacc
    11041 tagttttaga gatataaaag aaaaatatca tctaaaattt gaaaagaaaa aatacgtttt
    11101 gcaagtattt catccagttg taaccgaact agaaaatata gaaaaacaaa ttttagcttt
    11161 gatcaattca atggaacaac aatctcaacc aattatttgc attttaccta atagtgatgc
    11221 tggtagcgaa attatcagaa aaatgtacca gaaatattta aaaacggata ttatttatat
    11281 tacgaattta gagccggagg aatacctgac tatattaaaa gagtgcaaat ttatgatcgg
    11341 aaattcttct tctgggataa ttgaagctgc atcattcaaa ataccagtaa taaatttagg
    11401 aaccagacaa aatggacgag aacaatctaa aaatattata aatgcaaatc taaatgaaaa
    11461 tgaaattgaa actgctttga ataaaataca agatcctcag tttataaaaa gcttgaaaaa
    11521 tgttaagaac atctacggtg acggcaacag ttctagaaga ataacaaaaa cattgaatca
    11581 aatattgaat gatggggaag atattaagtg gattcaaaaa caaatagctt attaaaatat
    11641 actagtgatc catacattat tattggggct ggcggacacg caaaagtcat tattgaaacc
    11701 ttaagattag aaaataagtt aatatatgga ttttttgatg ataagcaaaa taaaatgcaa
    11761 gatctgaaat atcttgggaa aataaacgaa ttgaatagct gggcggatag caaaaaaaaa
    11821 atctataaat ttattgtagc tattggtgac tgtgtagtaa gaaaaaagat tataaaaaaa
    11881 ttgaatatgc caagtgagca atatggaata gctgttcatc caagtgctat agtggcaaaa
    11941 gaaatttcaa ttggttatgg aactgttatt tttgcgaatg ctgtaattaa cccagatgct
    12001 gtaattggag agcatgctat aataaacaca ggtagcattg ttgagcatga ttgtagaatt
    12061 aataactatg ttcatttatc tccaggtgta tgcttagcgg gtggagtaca tgtaggtgta
    12121 ggaactcaaa taggaattgg ttctcaatgt atccagatga agaaaattgg atcttggtgt
    12181 atgataggcg cagggagcac tattgttaag gatattccct cacattcctt agcttatggc
    12241 aatccagcta aaattaagaa agaaggaatt aattttgaat tctagaattt tattatcaag
    12301 tcctcatatg ggaggaacag aagaaaaata tgttgctaag gcttttaaag ataattggat
    12361 agcgccatta ggtgaaaatg tggataaatt tgaagaaagt attacaaaat atactggttc
    12421 taagggcgga gcttctgcgt taagttcagg tacagctgcc atacatcttg ccttaagact
    12481 gcttaatgtt ggaaaaaacg atattgtctt tgctccttca tttactttta tagctacagt
    12541 aaatcctatt ttatatcaag gggctgtacc agtgttcatt gactcagaac ctaatacatg
    12601 gaatatgagc cctgttgcac tagagagcgc attagaagaa gctgaaagaa acaaccaatt
    12661 acctaaggca atcatcgtag tgaatttata tggtcaaatg gctgattatg aacgaatttt
    12721 agctattgca aaccaattta atgttccagt gatagaagat gcagcggaat cgttaggttc
    12781 tacttataag ggaatttcgt caggcttatt tgggacaatt gggatctatt catttaacgg
    12841 taataagatc atcacaacct caggtggagg agctctagtg tctagtgata aaaaatatgt
    12901 tgagcattca agatttttag caacacaagc aagagatcaa gcaccgtatt atcaacatag
    12961 cgaaataggt tataattacc gtctaagcaa tatttctgcc ggtatcggac gtggacaaat
    13021 ggaagtattg aatgatagag tagctaaacg aagagaaatt ttcaatcgat ataaggaagc
    13081 tttttctgga attgatagaa ttgaaatgat gccagaagtg gatggcatgg tgccaaatcg
    13141 ttggttgtct actttaacga tcaatgatta taattctatt gatcaagtag ttaacgtaat
    13201 aaataaacta aatgaaaaaa acattgaaac aagagctttg tggaaaccac tacatttgca
    13261 accagtattt caaggggtaa aaatgtatta ccatgataat aatcttagtg tgtcagaaaa
    13321 gttatttaat agcggcttat gcttaccttc tggaagtaat atgacagata gtgaacaaga
    13381 atttgttatt gatgagttta aaaaaatatt caagtaggtg tgatatttta tgaacatagg
    13441 aattattggt ttaggttcca tggggaaaag aagacttaga ctcattcaag aacactttaa
    13501 tgatatttta ctatgtggtg ttgatactaa tgaggcgaga cgaaaggaag ttgaaaagga
    13561 atttggaata ccaacttata atagtctaac agaggcaaaa aatttgtttg aaataaattc
    13621 agtttttgtt tgtacatccc ctataaccca tgaatttatt ataaaagagg ctttaaattt
    13681 agattgtaat atctttacgg aaatcaattt attaaatgaa tattatgatg aaataatcga
    13741 agtagctaaa aagaaagata gattacttta tctatcttct acatttttga agagaaaaga
    13801 aattcaatat attaagtcta aagtgacgca taataaaaaa atttcttatc aataccatgt
    13861 aggacagtat ttacccgact ggcatccttg ggaagattat cgcaattttt ttgtttcaaa
    13921 caaaaaaact aatgggtgta gagaaatatt cgctattgaa ttaccttgga ttatagatac
    13981 atttgggaaa gttaaatcgt ttactgtaat gacccagaaa ttatccaatc ttgatattga
    14041 ttattcggac agtttcactc ttattattga gcatgaaact ggtatagttg gaactttaag
    14101 tgtagatgtt gtttcaagag tagctaaaag aaatttaact ataattggtg aaaagatttt
    14161 aatagaatgg gaaggtaacc cggattctct attttcatgg aatgaagaaa cttctagtat
    14221 gacagatatt caattgtacg atgaggttat gcatgataat aattattcac atactattat
    14281 tgaagatgca tatttagagg agattaaaga atttttcacg cttttggaaa agaaaatgga
    14341 accccaatat acttttgaaa aagataagta tattattaac ttaattaacg acattgaggt
    14401 aaattaatga tgaaagtaat tttttttggg ttagggtcaa ttggaaagag acatctaaaa
    14461 aatctaataa gctatggaaa aaagaattct attaattttg atataacagc ttatagtagc
    14521 agtggaaaaa aagagtttga agaaataacg tatattcaaa atagagacga tttggataca
    14581 cattatgata tagcttttat tacaaatccg acttttaagc atctggaaac actaaatgta
    14641 attgttgaaa aagttgatta catattttta gaaaaacctg ctttttctga gagtattgat
    14701 cttactcaat ataattatga ttacaaaaat atttatgttg ctgctccact gaggtataaa
    14761 aatatcatgg aagttgttcg taatagtatt caaagtaaaa aagtatattc tgtaagagct
    14821 atttgttcta cttatcttcc tgattggaga aaaggtactg attatagaaa taattattct
    14881 gcctttaaat ctatgggggg aggagtagaa ttagactgta tacatgaatt ggattatatt
    14941 ataaacctat ttggtttccc taaatcagta aaaaaacagt ttggtaaata ttcgaatctt
    15001 gaaattaaca gtaatgattt agcaacatat atattgagat acgatgataa aattatagaa
    15061 attcatttag attattttgg aagagttcct acaagaaaat ttcaattgtt tactttagat
    15121 gaatgtatca atgttgactt attaaataat aaaataagtt ttgaagaaaa cattgttaaa
    15181 gaaatgcctg aatctgctaa tgatatgtat gagaaggagt tgaaatattt ctttgaaaac
    15241 gtagtaacag gcaaagaaaa ctggaatgat ttatatcatg caaacgaagt attgaaaata
    15301 gctgaggaga aataaatgga aattttattt actatttgtg gtagagctgg gtctaagggg
    15361 tttaaaaata aaaatttgaa atatttggca ggaaagcccc tagtccattt cgctttagca
    15421 atgatagata tctatcaaca aaaacatcct gaacataatt gcacgacttg tttgaatacg
    15481 gacagtaatg agttagtaga attgacgact aagttaaatc cgtctgtgaa aattgtagaa
    15541 cgtaaacctg aattagctac agatactgta gggaaaattg aagtgatacg tgattcattc
    15601 ttacaactag aaagagaaga taatatattt gatttaatta tagatttaga tttgacttca
    15661 cctttacgtg aagtttctaa tcttgaagaa ttaatagatg aacatctaaa aaatttagat
    15721 aaagacgtct acttttcagt tgtttctgca agacgtaatc cctattttaa tatggtaaaa
    15781 agaattgaaa atgaagttac tatagttaat aaatcaagat acacatctag gcaacagaca
    15841 cctgaagttt ttgaaatgaa tgcctcaatg tattctttta aacctgaatt tctaaaaaaa
    15901 agtaattata tttttgatgg gcaatgtggg ataataaaaa tgagagatta tctaatttta
    15961 gatattgata gtgaagaaga ttttaaatgg ttagaatttt tgtttcctaa atttttagaa
    16021 gattcttcgg agcttcaaga tatctataat tatttatatc ggaggtaaaa ggatgagctg
    16081 ttatcttatc accggtgggg ctggcttcat tggttctacc ttagccaatc atttaggaga
    16141 agaacatgtg gtaatcgtcg tcgatgactt atcaatggga aaagtagaaa atcttgatat
    16201 gacgaaaaat atcactttta ttgagggaga tgtcgctgag aaatccttga tggaagagat
    16261 catgaaagct aataaatttg attatatctt tcatttagca gcagttgcta gtgtggcaga
    16321 ttcagttgcc cgaccagtag aaacacatcg tgtgaatttt gaaagtgtat taatgatttt
    16381 agaattgatc cgcaagtatc aacctgattt aaaacggatc gtgtttagtt cttcagcggc
    16441 tgtttatggg gatgaaccga ctttaccaaa aaaagaagag tccgtgattc gcccattgac
    16501 gccttatgcg gttgataaat tcgctgcaga acaatatgtg ctagattatt gtcatttata
    16561 tgatgtaccc ggtagcgcag ttcgtttttt caatgtctat ggtccaaatc aaaatccgaa
    16621 ttctccatac agtggtgtga tttctattct cgtagatcgc tataagaaac aaatcgtagg
    16681 agaagcaact tcatttacat tatttggtga tggaagccag tctagagact ttgtttatat
    16741 agatgatgta atccaagcat tacttttagt tgcgaatgag gaagctgcac tggggaaaca
    16801 attcaatgtt ggaacgggta aagcaaccac acttttggaa ttgattcatg caatcaatga
    16861 aattctcggt gtagaattga cacttgaata caaagaagag cgttcgggtg atatccatga
    16921 ctctctagca gatattacta agatccagtc aattggctat caaccgaaat atggtatttt
    16981 aagtggaatg actaattatt tgaaaactga aatcaattaa aacatactaa gataagatta
    17041 gagggtaaat tcaggctctt tgtcaataag gactgatgag ttttgtaaaa tcaaatctgg
    17101 gataga
//
LOCUS       DAFBSV010000060        17005 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.061, whole genome shotgun sequence.
ACCESSION   DAFBSV010000060 DAFBSV010000000
VERSION     DAFBSV010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.061"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(<1..124)
                     /locus_tag="LLB18_001895"
     CDS             complement(<1..124)
                     /locus_tag="LLB18_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HBK5244892.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVF"
     gene            complement(228..539)
                     /locus_tag="LLB18_001896"
     CDS             complement(228..539)
                     /locus_tag="LLB18_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBK5244893.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(541..738)
                     /locus_tag="LLB18_001897"
     CDS             complement(541..738)
                     /locus_tag="LLB18_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HBK5244894.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1132..2859)
                     /locus_tag="LLB18_001898"
     CDS             complement(1132..2859)
                     /locus_tag="LLB18_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HBK5244895.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2852..4045)
                     /locus_tag="LLB18_001899"
     CDS             complement(2852..4045)
                     /locus_tag="LLB18_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HBK5244896.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4232..4876)
                     /locus_tag="LLB18_001900"
     CDS             complement(4232..4876)
                     /locus_tag="LLB18_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK5244897.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4970..5104)
                     /locus_tag="LLB18_001901"
     CDS             complement(4970..5104)
                     /locus_tag="LLB18_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBK5244898.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5106..7238)
                     /gene="feoB"
                     /locus_tag="LLB18_001902"
     CDS             complement(5106..7238)
                     /gene="feoB"
                     /locus_tag="LLB18_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBK5244899.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFFMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7235..7708)
                     /locus_tag="LLB18_001903"
     CDS             complement(7235..7708)
                     /locus_tag="LLB18_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBK5244900.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8109..8333
                     /gene="nrdH"
                     /locus_tag="LLB18_001904"
     CDS             8109..8333
                     /gene="nrdH"
                     /locus_tag="LLB18_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HBK5244901.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8492..10651
                     /gene="nrdE"
                     /locus_tag="LLB18_001905"
     CDS             8492..10651
                     /gene="nrdE"
                     /locus_tag="LLB18_001905"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBK5244902.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10701..11666
                     /gene="nrdF"
                     /locus_tag="LLB18_001906"
     CDS             10701..11666
                     /gene="nrdF"
                     /locus_tag="LLB18_001906"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBK5244903.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11755..12894)
                     /locus_tag="LLB18_001907"
     CDS             complement(11755..12894)
                     /locus_tag="LLB18_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBK5244904.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13203..13916)
                     /locus_tag="LLB18_001908"
     CDS             complement(13203..13916)
                     /locus_tag="LLB18_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBK5244905.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14170..14871)
                     /gene="nagB"
                     /locus_tag="LLB18_001909"
     CDS             complement(14170..14871)
                     /gene="nagB"
                     /locus_tag="LLB18_001909"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBK5244906.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15105..16637
                     /locus_tag="LLB18_001910"
     CDS             15105..16637
                     /locus_tag="LLB18_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBK5244907.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16828..>17005)
                     /locus_tag="LLB18_001911"
     CDS             complement(16828..>17005)
                     /locus_tag="LLB18_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5244908.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5279 a         3494 c         2909 g         5323 t
ORIGIN      
        1 aaaaaacaca ttccactaaa tttgatgccg gttttccttg aggttttgtt ccagcacctc
       61 ctttaatttt tttaagctct tgatctgaac attgtttagc atttagtcta tttttttctt
      121 ccattacgat tccccctaca aactataaat acttttatgt cactgattca atatacctat
      181 ttttctaatc aaaaaatttt gagacatatt taatattata agtatcatta aaattgagat
      241 ttatctccat aatctgctcg atataaacca tttattccag cagttcttcc aatttcactc
      301 aaatttctta ttaattcctc ttgatattca gtgaatctta ttttattagt ataagcagta
      361 aaatatagat aattcaccaa tctatttatt aaaggactgg gatctaattc atatttttgt
      421 ttttctaatt ttaaatatac cttttgtaaa acctcaagaa tatcagaata tttaggatct
      481 ttacttatag atatatcatt atataattca tgaacaattt gcttagcatt ttttttcatt
      541 ttagcacttc cctggaattg ctccacctaa aaaaccacct atagacattc ctgcaataca
      601 agtagttgcc ttggcccaat cgaccgtaca tttattttta gtgcaataca ctccatttcc
      661 ataatatttt ccactatgag tggtaccccc atagataagt tgtgtctctt taatagacaa
      721 aatttttaaa tgtttcataa tctaatcacc cctaaattaa tgtttttaga ctattattct
      781 aacattcatt aaatttcaaa aaacaattcc ttcttgaaac gtagcaaaat aattcctgaa
      841 taagaattta atcactttta agtatataaa ctatgtatat tctttaatat tttttgagaa
      901 tgcacttcgt acataataaa ctttaatcac attagtcttt catacctacg atcgatctct
      961 ttgactcgca cccataaatt cataatagtt tgtcggcgtc tttgaacgtt tcgaagatga
     1021 gctacgcatt ctcttttttt atagacaaaa aagatagaga cgaacatgga gcttccaaat
     1081 ttggatattt gatccaattt tggaagctcc atttatttcg tgtctgtctt tttatttttt
     1141 ccagctttcg actaattctt ggttctcttt gatccagtct tttgctgctt gctgtggatc
     1201 ttttccattg ttgatttcca acataacttt ttccatatct ttttctgacc aatggaaatt
     1261 gtctaatact ttgtaagctt ctggctggtc ttctttcaat ccttttcgaa ccatcgtatg
     1321 gatctgctct tcgcttccca ttccgttttc aggatcttct aagtatttca gatcatattt
     1381 ggcaaacatc caatgaggtg tccatcctgt aactacaatt ggttcgtgtt ttttgatcgc
     1441 ttgacctagt gcaacggtca ttgctcctga agaagatgtc tctactttcc agtctttcaa
     1501 gttgtcatat ttttggatcg tgttttcagc agccgtaact acaccagctc ctggctcgat
     1561 tcctatgatt ttcttacctg cctgatcggt taactcatcg atcgaattta catccatgta
     1621 ggctggcact gctaaaccaa cttttgctcc tgtcaaattg gcacctaggt cttcgacttg
     1681 atctttatat tgtgcatatt gtgaaccatg agttttaggt agccaagctg aaaccatggc
     1741 atctgactcg ccatttgaaa cagatttcca catgattgaa ttatctaatg gcgtcatcgt
     1801 tacatcatag cccatttgtt tcaatacttc accgactaca tttgttgaag caacttctgt
     1861 atcccattca acataagata agttgatacg ttttgtttct ttggcagatg aaaaactccc
     1921 tataccaatc gcacctaaga tcactactac tacagcacca atgatcagtc cttgacgttt
     1981 tttacttttc tgtgttgttg ctcctgcagc ttttttattg tttggctggt tcaaatgctg
     2041 tgtaaaacgg tcaatgatga ttgctaagat aactaatgca accccgttga caaatccatt
     2101 cccgacttgt gctctttgca atgctgataa tacgccgcgt cctaagccgg gtgcaccgat
     2161 catagaggca ataacgacca ttgaaagtga cagcattgtt gtttgattga tccctgccat
     2221 gatcgtactt ttagctaaag gcaattctag tttgaatagt ttttgacgac ttgtgctccc
     2281 gaatgaatca gaagcttcta ctaattcttt aggaacttgt cgaatcccta aattcgtaaa
     2341 acgaacggtt ggtggcagag caaagatgac tgaggcaaat acccctggaa ccatcccgat
     2401 accgaaaaat gcaactgctg gaatcaaata aacgaatcct ggcattgtct gcataaagtc
     2461 aaggatcggt ttgataatac tttgggcttt actgcttttt gccatcaaga tccctaatgg
     2521 taccccaatg atgatcgaga tcacactaga taaaagaaca agtgtgacag tattcatcaa
     2581 atcattccat agaccttggt tataaataaa ccatagaccg attaatgtga acaacgtaag
     2641 tcctggacgt ttcttagaaa taaagaaagc tgctaccgtc aataacaaga taaacaaagg
     2701 agctggaatc actaacagta aatttgtaat ccccgacatc actgcctgtc caatcgtttg
     2761 taaaaatgaa aataggccag aaaaagttgt cgtaaaccat tctgtgatat tttctaccca
     2821 gtttgccact ggtaattgat agttcaatag attattcatg ttcactcacc tcgcttgttt
     2881 ctgctaatgc ttcaatcaca ctacctcgga tgacgacacc ttttaatttt ccatcctcta
     2941 caactgcaag tggagtcggt gagtcataaa taatattgaa aatatcactt accaccatgt
     3001 ctttcccaat caccgtcaca ttttcatcta ggaagtcgat caatggacgt ttttgcttcc
     3061 tagcttctaa cgcttgatct gcagtgatga tccctttcag gtgtctcttt ctgtcaacag
     3121 ccatcagcat gctgacttct tcattacgca tccttgtcaa tgcaacgttt ggtccatcag
     3181 attcgatatt cgtcgtcaat gcaggtacca tgatgttttg agccgtaagc actttggaac
     3241 gatcgacttc ttccacaaat tcacgtacat aatcatttgc tggattggtc aatatttctt
     3301 cacctgttcc gatctgcatg atttcgccgt ctttcatcaa ggcgattctg tccccaatcc
     3361 gtaaagcttc attcaaatca tgggtaatga aaataatcgt tttttgaaca ttggcttgca
     3421 ggtccagtaa ttcgtcttgc atttctcgcc ggatcagcgg atcaagagcc gagaacgctt
     3481 cgtccatcag caagatctca ggatcatttg ctaaagctct ggctaggcca acccgttgtt
     3541 gcatcccacc agataactga ctaggatatt ggtctttaaa tgaaagcaaa ctagaatttt
     3601 ctaatgcttt ttctgctttt tcttgtcgtt cttctttagg tacaccacgg acttctaacc
     3661 cgtattctgt attttccaag atcgttcgat gtggaaacag accgaagttt tggaaaacca
     3721 tattgatttt atgacgacgg acttctcgca attcttcttt gcttaacttc gatacatctt
     3781 ctccatcaat atagatactg cccgaagttg gctcaatcag acgattcaat agacggatca
     3841 atgtggattt cccactcccg gaaagcccca tgatcacgaa gatttctcct tcttttacgt
     3901 caaaattcac gtcatacaca ccaaccgttg caccggtttt ctttaaaatc tccgttttcg
     3961 gctggtgatc attcatcata tctaaagcgg cttgtgtctt tttaccaaat atctttgtta
     4021 aatgttttac ttctactttt accaaacaaa ttctcctttt ttatgtaaat tcatttttct
     4081 ttctgaaaaa agtgaccaca ctatgttaac atcatgtagt cactttgtca aaaatgaaag
     4141 aaatttgctt gtccaaactg aaaaaaactt ggctaaatct ttgtaaataa aaggtttagc
     4201 caagttaata tttttttaat atttcacaca atcattctgc aagctgatgc tccgggtaaa
     4261 aaaagtttgt catacgctgt agtgtatatt catttccaat aaaatgaacg atgtcccctg
     4321 ccgtaaattt agcatagggg ccaggtgaaa caagcagttc ttcattatga gaaattgcga
     4381 taactgtggc gccagtcgcc tgccagatat tcaactcgct aattgaacgg tccagatgca
     4441 ttgctttttc tgataaagat aattcaaacg gaagtaaagg attcatctta tgtattcgct
     4501 tcgtttgatt gaccagctga tccaataatt gagaaaaatg attcagctca tcttgttgct
     4561 tctccacact tgccatgatt tctgcttttg tatcttggat ggattgtaca tcttgatatt
     4621 gcaataggaa atcttttgct ttttccttcg aagcaacaaa tgccccactt ccatgccgta
     4681 cttccatgat tccaagatct accagcacat tgatagcctt gcgggtagtc tcaggagaag
     4741 cattgtacgt actggcaagt gttgagcggg catggatctt ctcacccact ttatatcggt
     4801 tttcaacgat acgttcggct aaatcaacag caatctgctg gtagcgcggg cggacgattt
     4861 ttttctttcc agacattttc tttcctcttt ctttttttac tttccctcat cttactatgc
     4921 tctagcaaaa taagcaaaaa aggggagaat agcctcttgc aacgactgat catcgcttga
     4981 tctgttcctt ttttactggg caagctgttt gacagtcatc acaattctta ccggatttta
     5041 aacgagtata gacaattgcg cctgcacttc caaagattaa cacacttaat aagaatgtcg
     5101 ccatcctatt cctctccttc taatgacaat atagtataaa actggttctt ggattttggc
     5161 tgacggaaca aaacataaac gagtcctatc atcagtaaaa tagcaagata cgtccctaac
     5221 gctacctgtc caccctccaa taagtgtccc aactgataaa tcacaaaact aactaaataa
     5281 gctaaaccgc attgatagcc tatggcgatc caagtccatt tcttggcatt catttcccga
     5341 tggatagccc caattgccgc aaaacaaggc gcacaaagta aattgaaggc taacaatgaa
     5401 taagctgctg cgggagtata tgtgtgttgt agcacttgcc agatttctct gccattttcg
     5461 gatacttccg catgaccaaa caaaatacca aatgtgccaa taatattttc tttagcgacc
     5521 aatcctgtaa tcgctgcgac tgttccttgc cagtttcccc aaccaagcgg ctgaaaaaca
     5581 actgccagga ttcgcccgaa aaaggctaag atactttggt cttcagaaac aggttgagca
     5641 taaaaattat aagaagagct gaaccagatc acgatactag aaacaaagat aatcgttcct
     5701 gcttttttaa caaaagactt gctgcggtca taggtttgtc ttaggaccgc tgaccattga
     5761 ggaaaatgat atgcgggcaa ttccatgata aaaggagctg tatctccagc aaacaaacgt
     5821 gtttttttca agctgattcc agagaaaata attgcagtca taccaagaaa ataggcagaa
     5881 ggagctaccc aagattgatg aggaaaaaag gcccctgcta ctaaggcaat aatcggcaac
     5941 tttgcagaac aaggcatgaa ggttgtgacc atgatcgtca aacgacgatc ttgctcgttt
     6001 tcaatcgtgc gactggccat gacgcctggc actccacatc ctgtagcaat cagcatagga
     6061 atgaaggatt ttcctgaaag accgaatttc ctgaaaagtc gatccatgaa aaaagcgatc
     6121 ctcgccatat atccgcagtc ttccagaaag ctcaagcata aaaacaatat aatcaattgc
     6181 ggtagaaatc ctaacactgc tcccacgcct gcgatgatgc cgttcaagat cagctcctgc
     6241 atccatcccg ctacttgcca ttcagctaac aatctgccaa catgttctgg taaccatgta
     6301 ccaaacaatg tgtcattgat ccaatctgtc cccattgttc ctactgtttg aatagccaga
     6361 taatagatca gccacatcac aaatgcgaag atcggcaagg ctaaccaacg attcgttgca
     6421 atctgatcga ttttgtcact catcgataat tggaaagaat catttgacac aacacagagt
     6481 gtacatagtt gggtaataaa ttcataacgt tcattgacca gaatcgtctc actatcgtcg
     6541 tccaatagtt tctctgttaa ctggatcagt tgctcgatct ctttttgctg agaaactgct
     6601 atctcgtaat cctctcttac cttctgatct cgttcaaaat atttcattgc ataccagcgt
     6661 ttcttgccgc tttgttctcc tagtacatct tcaatttcat gtaaagctgc ttctaaacgt
     6721 ggatcatatg tacagggaac aggaatagaa ggccgctttt ttgcagactc ctgaatcttt
     6781 tcgattagtt tttcgattcc ttgctttttc aatacgctga ttggtaaaac tggtacacca
     6841 agaccatagg aaagcttttc tagattgatt ttttttcctt cttttttgat gacatccatc
     6901 atattcagac caatgatcat aggaatgtct aaatccaata actgcgtagt taaataaaga
     6961 tttcgttcta aattggtagc atcaataatg ttgatgatca gttcaggctg ttcctgaacc
     7021 aaataatctc ttgcaatcac ttcttctggt gtataaggag acaaagaata gatgccgggt
     7081 aggtcctgaa tatgaatgtt cggatttttt ttcaacgatc cttctttttt ttctactgtt
     7141 acgcccggcc aattccctac atattgattc gaaccagtca agagattgaa caagctagtt
     7201 ttcccgctgt ttggatttcc gactaacgcg atattcattc tttttcctcc ctttgtatca
     7261 agattagttc ggcctctgac tttcgtaacg tcagttcata ccctcgcact gtcagttcga
     7321 ttggatctcc cagaggggct agttttcgga taactatttt tacatttcgc gtcaatccca
     7381 tatccattaa ccgtcgcttc actgcgcctt gtccgtggat tgctacgacg atcccagtct
     7441 ctcctgcttt taattgatca agagaagtcc agctttcaga ggaagcagtc tttttattga
     7501 caaagatttg acctagtatt tcccgactta ctgccactcg atgacttttt accagtaaaa
     7561 tggcattgtt gcctgataaa ttgacgacga cgattttact tccggcaacg atcccgatat
     7621 tttgcaaatg gcgttttgtt ttttcttctg tttcgattcg ttcgacttga taaacgaaat
     7681 tctgctttgc ctgcgctaag gtctgcatat tgattcctct cttgtgaaat aaatcatgta
     7741 ttaaaatcat tcattatatg ttctaatttt cttacgtgtt acgcaaataa atgagaatca
     7801 ttctcacata gaatactctc ggtaattgag aatgtcaatt atacttgtga tattatgagc
     7861 gaatctttag tattgataga taaaaatgag aaaaaaatat ttcttcatag ttttccacaa
     7921 ttttttctct attaaatttg ctattttccc acacgatact tgttttcagc tcttttttca
     7981 aaaacacaaa acttagtatt ccacagtttc cacaacacaa tatgtagtgt ttgttgtttg
     8041 acttttttac taagagtttt atactatcta ttatagataa taagaatgtg ttagaggagg
     8101 cactcaccat gaacgtaaaa atcttttcta aaaataattg tatgcaatgt aagatggtca
     8161 aacggttttt aacagaaaat caaattgctt ttgaagaagt caatatcgat gaacagcctg
     8221 aagcagtaga ctggttgaaa gcacaaggat tccaaagtgt tcctgtcatt acttctgatg
     8281 cagaaacagt tatcggattc cgtcctgatc agttgcgtaa acttgccagc taacatgact
     8341 aaaagaatca aaacgtgata catggatttg aagggcttga gacagcacca gtttttgtcg
     8401 caaacttcca aatccttttt taaagcttaa aaacaatgca atgatttgca atcaagcatc
     8461 atcaaatacg aaatgaaggt tgggcgtacg tatgagtctt aaaaatttac aagatgtcag
     8521 ttatttcaag ctgaataatg aaatcaatcg gccagtcaat ggtcaaatcc ctttgaataa
     8581 ggataaagaa gctttagttg ccttttttga ggaaaatgtc aaaccaaata cgatgacttt
     8641 tccatctatt atggaaaaaa tcaattactt gatcgatcaa gaatatatag aagcagaatt
     8701 cattcaattg tattcaccat catttattga aaagctatat caatttttgg acgagcaaca
     8761 tttttctttc aaatctttta tggctgctta caaattttat tctcaatatg cgttgaaaac
     8821 caacgacggt tccgcttatc tggaaactta tgaagatcga gtagccttca atgcgcttta
     8881 ctttgcgaac ggggatgaag aattagcact tgctcttgca gacgaaatga tccatcaacg
     8941 atatcagcca gctacacctt ctttcttgaa tgctggacgt aaacgtcggg gcgaattggt
     9001 gtcttgtttc ttgactcaag tcactgacga tatgaactct atcgggcgct caatcaactc
     9061 tgctttgcaa ttgtcccgta ttggtggcgg cgtagggatt actttatcaa atcttcgtga
     9121 agccggcgct cctatcaaag gatatgaggg tgctgcaagt ggtgtcgttc cagtcatgaa
     9181 attattcgaa gatagtttca gctattctaa tcaattaggt cagcgtcaag gagctggcgt
     9241 ggtttatttg aacgttttcc atccagacat tattgctttc ctttcagcaa aaaaagaaaa
     9301 tgcagatgaa aagattcgcg taaaaactct ttctcttggc gtgatcgtac ctgataaatt
     9361 ttatgaattg acacgtaaaa acgaagatat gtatttattt agtccatata gtgtcgaaaa
     9421 agaatatggt gtcccattct cttatgtaaa tattacagct gagtatgatc atctagttgc
     9481 aaatccaaac attcgcaaac aaaaaatcaa agcgcgtgat cttgaaaatg aaatctcaaa
     9541 attacaacaa gaatctggct atccttacgt aatcaatatt gatacagcga accgcgagaa
     9601 tccaatcgat ggcaagatca tcatgagtaa tttatgttca gagattttac aagttcaaac
     9661 gccttctgtg attaacggca aacaggaata tgaagtatta ggaacagata tctcatgtaa
     9721 cttaggctcg acaaatatcg tgaatttgat gcaaagccct aactttggtc aatctgtgcg
     9781 tacgatgact cgtgcattga catttattac agatgcatct gatatcgatg tcgtaccacc
     9841 gatccaaaac ggaaataagc tgaatcatac gattggatta ggtgccatgg gcttacacac
     9901 ttatcttgca aaagaacaaa tggaatatgg ctcagaggat tcattagact ttacaaatat
     9961 ttacttcatg ctgttgaatt attggacact tgttgaaagc aacaatatcg ctcgtgaaag
    10021 aaaacaagtt ttccataatt ttgaaaaatc agcttatgct gacggcactt atttcgaaaa
    10081 atacgtaact ggagaattcc agccaaaatc agaaaaagtc aaagcattgt ttgaaggcat
    10141 ttttatccca actgctgaag attggaatgc tttgaaacaa gcagtaatga aagatggact
    10201 gtatcatcaa aatcgcttgg cagtagcacc aaatggctca atttcatata tcaacgatac
    10261 gagtgcaagt attcatccta tcactcgcat gatcgaagaa cgccaagaga agaaaatcgg
    10321 taaaatttat tacccagcgc cttatctatc caatgagacg attccgtatt acacttctgc
    10381 ttatgatatg gacatgcgta aagtaatcga tgtttatgca acggcacaac aacacgtcga
    10441 tcaaggcatg agtttgactt tattcatgcg ttctgaaatc ccagaaggca tttatgaatg
    10501 gaagacaaca acgaagcaaa cgacacgtga tttgaatatt ttaagacatt acgctttcca
    10561 caaaggaatc aaatccattt attacgtacg tacctttact gatgatgcag aagaaatcgg
    10621 aagcaatcaa tgtgaaagct gcgtgatcta atatcataga tagattcgct tattcatatt
    10681 ttaattaaag gagcattctc atgtcagaaa catattatga agcaataaac tggaatgaaa
    10741 ttgaagatat cattgataaa tccacttggg agaagctgac agagcaattt tggctagata
    10801 cacgtatccc actttcaaat gacctagatg attggcgtac attgtctcaa ttggaaaaag
    10861 atacagtagg acatgtattt ggcggtttga cactgctaga tactgtccaa tctgaaagtg
    10921 gcatggatca gttgcgtaaa gatgtccgca ctccccatga agaagccgtt ttgaacaata
    10981 ttcaattcat ggaatccgtt catgccaaaa gttattcttc tatttttagt acactgaata
    11041 cgaaaaaaga aatcgaagaa atttttgact ggacaaatac gaatccttat ctgcaaaaaa
    11101 aagctgagcg tatcaatgaa atctacaaac acggtacacc gctagaaaag aaaattgcca
    11161 gcgtcttttt agaaacattc ttgttctatt caggttttta tactcctctt tattatttag
    11221 gaaacaacaa attggctaac gtagcagaga tcatcaaact aatcatccga gatgaatctg
    11281 tacatggaac ctacatcggt tacaaattcc aattaggatt caacgagtta cctgaagcag
    11341 aacaagaaac gttaaaagac tggatgtaca atcttcttta tgagctttac gaaaacgaag
    11401 aacgttatac agaagaatta tacgatccaa tcggctggac agaagaagtc aagacattcc
    11461 tacgctataa tgccaacaaa gcattgatga acctagggat ggatccactc tttccagata
    11521 ctgccaatga tgtcaaccca atcgtaatga acgggatttc aacaggcaca agcaaccatg
    11581 acttcttctc acaagtcgga aacggctatt tgttaggtca tgtagaagcg atgaaagacg
    11641 acgattattt gattggattg gaataaggat ttattttaat tcaaaaattt ttcgaaaaat
    11701 aaaaagagtt tagcgtacag atattttaaa tgtacactga actctttttt atgcttattc
    11761 acttgtttct tccagcactt ttggactgtc taacttttcc gaaacatgtt ccattcttct
    11821 caataaatag attttccgga tatttaatat tatcgtctta atcactgcat agacaggtat
    11881 gcaaatcagc atgcctaata ttcctgcgac acttcctgct ccaatcaata ccaagatgat
    11941 cgtcaaagga tggatattca ttgatttccc aaataacaac ggcttgatca aatttccatc
    12001 taattgttgg atcactaaaa tcgacaacgc catatacaaa gcttgaaatg gagagataaa
    12061 caaaccgaca atgattgctg gtaccgctcc aataaaaggg ccgacatacg ggataatatt
    12121 cgtgattccg caaatgaccg caagcaacaa gctataaggc tgatcgaata ttctcattgc
    12181 caaaaagctc attacaccaa taatcaaagc atctaagatc gtactgctga tataggcaga
    12241 taatgtttcg tttaattctt ttaccgtttg gcgtaactct ttacgaatcg ctttcggaaa
    12301 gaagtgagac aacgcatcaa taaatttgtg cccatccttg aacataaata gcaaaataaa
    12361 tggaacggta aataacaaaa taaaaaattg catcataaat gaaatgattt ttgagacact
    12421 tgcagataaa ctgactaata tgatattgaa caaattacta agagataaat ttgctgatgc
    12481 taattgttct tccaaattga aatttttaaa ctcttcccgc tgcgccaatt catttaacca
    12541 tttgcttgtt tcatctgcat acattggcaa gctctgggtc aattgaattg tctgttccat
    12601 taactgaggc actacattca tgacagttaa aacaactaaa atgattacga ccaaaaacgt
    12661 caataaaaaa ccgaacactc tcgggatccg atgcttttcg agaaaaacaa cgattggatc
    12721 gaacatataa tagataaaac cagcaacaag caatggtaaa aaaattgccg aaagcatttt
    12781 caatattgga ctaaaaatat tcggcatttg taaaataaag tacacgccga tgatcgtgag
    12841 tactagctcc actgtccaga aaaataattt tgattgttta aaacgtgatt gcatacatct
    12901 cctccaaggt cctttgatac ttctattcta tcatttaaca aagagttacg cgctgagatt
    12961 ttcatttgct taaaaaaaac aaaaaaaata aacatatttt aatgagtaga cgagtactta
    13021 aacaaaaaca cggtttggag tagtgacaaa aattatactg cagtcccttt ttccaaataa
    13081 acggtgttca aaagcttgca tcttcgtaat aagcccagcc aaacgaaaaa tataaggaac
    13141 tatttttatt tggctgggct tattacttga tgtaggacat ctattttaca acctcagatc
    13201 atttattgcg caatactgac taaatgcaac tttgtgatat ttttgtgtac ggacaactcc
    13261 tcgatcacat cggcataagt gagccctttt ggaagatcaa tcgtatagat atttttgtac
    13321 actcggtagt catcaacgaa ttttacgtca aaattcacat cttcgattac gatatttttc
    13381 tcttcaaaat aatcggtaag aaaatctttg gtttcttttc tatggataaa ttggatttct
    13441 aactttttag tcgtaggtac atggatcacg cgtttcacta ctgtgagtgc aatagcaatc
    13501 ccgataaaac tgatgatcgc aatggaatag taacccatgc cgatggcgat ccctaatcca
    13561 gcaattgccc ataaagaagc ggcagtcgta agtcccgtca ccgattgttt cgtgacgatg
    13621 atcgttcccg cgcctaagaa accgacacca ctcaccactt gagcaatcag ccttgcttca
    13681 tctgaacgaa tcgttccagc aagctgtgga tactctaaag catctcttaa tgcaccacta
    13741 gcgatctcaa cttggatcaa tgcaatgata catgctccca tacaaactaa aatatgcgta
    13801 cgcatacctg ctggacgatt tttatattgt cgttcaaaac cgattgctcc gccaaatagc
    13861 atagcgatcc ctaaacgtaa aataatctct ggaattgtca ataccatatc attcatctaa
    13921 acaccctcca gtccaatata tcatgtctga aaggagcaga caaaaaaagt gcaattttta
    13981 cctcttacga aaaaaggact gtgacaaaat ttttgtcata gtccttttta tgaataaacg
    14041 gtgttcaatc agctgaccct cggtattact caacaaacgg caaaatatgg ggagctattt
    14101 ttcctttgtc ttctctaata ctcaggtcaa aacgctgatt tcacaacctc tttagcctac
    14161 tattgaaaat tacaacttac ttgctgcttc ttcatcgatg atcacaacaa cattgtcgtg
    14221 attttgcaat acacttgctg gcaaatgatt cgttacaggt ccttcaatca tccctttgat
    14281 tgcatcagct ttgctttcgc caaatgccat caagacgatt tctttacttt tcataattga
    14341 accgattccc attgaaacag cttttgttgg tacatcttct gctttatcga agaatcgttt
    14401 gtttgcattg attgttgatt ctgttaagtc aactactgaa gtcgttccgt caaatgaagc
    14461 accaggttca ttgaaaccga tatgtccatt ttgcccgatt cctaagattt ggatatcgat
    14521 tggatgtgca tcgatgattt gatcatactt tttgcatgct gcttccagat cttctgcttt
    14581 tccatctggt acaaacgttt ctttgaatgg ttttttatca aataattgga catccatgaa
    14641 atgacggtag ctttgttcat ctgaaccgcc tagtccaacg tactcatcta agtttacaga
    14701 agtcatttca ctgaaatcca aatcgcttga agtcatttct ttatataaag taactggtgt
    14761 gcttcctgtt gccaatccta atacttttgc acctttgttc ataccttctt tgatgatttc
    14821 aaatgctttt tttccgcctt cttcagcgtt ttttacacga atgatttcca tagtgattgc
    14881 tcctttatat tttggtatag cccaattata gcattctttt tttcttttta caataattag
    14941 tatagaccaa attgcatttt tttcattttc ttgacaataa ataggaatcc gtgttaggtt
    15001 tcataagatg gttcaatcaa acaatccatg ttgcatgaaa accaagcaag tgattcactg
    15061 tggacgcttt atgtctgcag tttttttatg aaaaaggagt tattatgagt atactgacat
    15121 taaacaacat tacccagcaa tttggcgaca aaatcctcta tgaaggtgtc gatctgcaat
    15181 taaatgctgg cgaacatctt gggctgattg gacaaaacgg agccggtaaa agtacattga
    15241 ttaaaatcat cactggtgag atcttaccag atgacggaca gatccattgg caaaaaaata
    15301 ttcacaaagg ttacctcgat caatatgtgg aagtcgatga aacattaaca atcgaagaat
    15361 ttctaaaaac tgcgtacgca aaagaatacg aaaaggaaga aaaaattgct tttctttacc
    15421 aaacatatag cgagaccttc gatgattcct tgctggaaaa agctgggaaa ctccaaacgg
    15481 aattagacca aggagtgttt tatcaaatcg acaccttagt tgctgagatg agcagcgggt
    15541 tggggatcga tgtcttaggt ttagattcac tgttgaaaaa tctaagtggt ggacaacgtt
    15601 caaaggtgat tttagcaaaa ctacttttag aaaacccaga tgttctgatc ttagatgaac
    15661 caaccaatca cttagatgat cagcatatcc aatggctgac gcagtttctt caggattttg
    15721 acggtgcgta tatcgtgatt tcccatgacc aagaatttct tgatcagatc accacccata
    15781 tcgcagacat cgagtttgga aagattacta agtatactgg ccatctaaaa caagcattga
    15841 aacaaaagga acaaaatcgc gaaagctatt tgcgccaata tcatgctcaa caaaaacaaa
    15901 tcgaaaagac cgaagcttat attcgaaaat acaaagccgg ttcccgatca acgatggcaa
    15961 aaagccgaca aaaacaatta gataaaatcg aacggctgac gcctccagct tcagcaagta
    16021 aagctgtctt tgattttcca ttctcgccta ttgtcacgac attagcagtg gaaacaactg
    16081 atttagtcat cggatatgat cgaccgctac ttgcacccat caatttgacc atccgctttg
    16141 gtgaaaatat tgccattcga ggcttcaacg ggattggaaa atctacttta ttaaaaacac
    16201 tgatcggtga gattgaaaaa ataagtggcg atttccactt cccagataac acaaaaatca
    16261 attacttttc acaagatctg tactgggaaa atccattaga aacaccacta caatatttaa
    16321 gcagtcaatt tccaaaagcg actatcaaag aattacgtcg ccaactagct aaagcagggt
    16381 tagttaatca attagcaagt gaacctctca ctacattaag tggtggggaa caaactaagg
    16441 tgaaacttgc acagttgaca atgaaccaag gtaatttact gattctcgat gaaccgacga
    16501 accatatcga tcaagaaacg aaagaaagct tacaagacgg gatacagaaa tttccaggaa
    16561 cagtaatcat cgtctctcat gaacaagaat tttatcaaga tcttgtgcaa cgagtcattg
    16621 agattgaacc aaaataaacg tttgattgaa tagttgaaaa aaaggagctg tgacaaaagt
    16681 tttgtcacaa ctccttcttc tgaataaatg gtggccaatt agctgacctt cggtattagc
    16741 tcaaaaaacg gcaaaatatg aggagctatt tttatttggc tattcttatt acttgatgca
    16801 gaacagcttt tcacaacctc ttttcgtcta ttttttattt tcgagatttc tctttccttt
    16861 aaaaacaact gtttgaaaga agaacgcaca tccttgaaaa acaagcccgc taaccgttac
    16921 acctaaccag ccatactgct gccacattgt cgtccctagc aatgaaccag ccgcacctcc
    16981 aataaagtac ataaacataa ataca
//
LOCUS       DAFBSV010000061        16636 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.062, whole genome shotgun sequence.
ACCESSION   DAFBSV010000061 DAFBSV010000000
VERSION     DAFBSV010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16636
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.062"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(421..1116)
                     /locus_tag="LLB18_001912"
     CDS             complement(421..1116)
                     /locus_tag="LLB18_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBK5244909.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            1270..1548
                     /locus_tag="LLB18_001913"
     CDS             1270..1548
                     /locus_tag="LLB18_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244910.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            1567..2775
                     /locus_tag="LLB18_001914"
     CDS             1567..2775
                     /locus_tag="LLB18_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5244911.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(2923..3288)
                     /locus_tag="LLB18_001915"
     CDS             complement(2923..3288)
                     /locus_tag="LLB18_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HBK5244912.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(3435..4208)
                     /locus_tag="LLB18_001916"
     CDS             complement(3435..4208)
                     /locus_tag="LLB18_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBK5244913.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            complement(4382..5242)
                     /locus_tag="LLB18_001917"
     CDS             complement(4382..5242)
                     /locus_tag="LLB18_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBK5244914.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            complement(5242..6660)
                     /locus_tag="LLB18_001918"
     CDS             complement(5242..6660)
                     /locus_tag="LLB18_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK5244915.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            complement(6717..7166)
                     /locus_tag="LLB18_001919"
     CDS             complement(6717..7166)
                     /locus_tag="LLB18_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK5244916.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            complement(7611..7874)
                     /locus_tag="LLB18_001920"
     CDS             complement(7611..7874)
                     /locus_tag="LLB18_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HBK5244917.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            complement(7973..9268)
                     /gene="rho"
                     /locus_tag="LLB18_001921"
     CDS             complement(7973..9268)
                     /gene="rho"
                     /locus_tag="LLB18_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBK5244918.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            complement(9265..10536)
                     /locus_tag="LLB18_001922"
     CDS             complement(9265..10536)
                     /locus_tag="LLB18_001922"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBK5244919.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            complement(10701..11570)
                     /locus_tag="LLB18_001923"
     CDS             complement(10701..11570)
                     /locus_tag="LLB18_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HBK5244920.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            complement(11862..13472)
                     /locus_tag="LLB18_001924"
     CDS             complement(11862..13472)
                     /locus_tag="LLB18_001924"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HBK5244921.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(14665..16005)
                     /gene="glnA"
                     /locus_tag="LLB18_001925"
     CDS             complement(14665..16005)
                     /gene="glnA"
                     /locus_tag="LLB18_001925"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HBK5244922.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            complement(16033..16425)
                     /locus_tag="LLB18_001926"
     CDS             complement(16033..16425)
                     /locus_tag="LLB18_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBK5244923.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
BASE COUNT         4753 a         3531 c         2831 g         5521 t
ORIGIN      
        1 caaaaaaagg gctgtgacaa aaatcgtgtc acagcccctt ttgttgcaaa taaacggcgt
       61 tcaaaagctt acatctacgg tgataagtcc agccaagtta aaaacataag agactgtttt
      121 tacttggctc ttcttattac ttgatgcaga acagcttttt cacaacctct tggtaaacgg
      181 tgttctccta ccaactcctc ggtcacaagt cacaatattc atcaaacatg aaaagctgtt
      241 ttttgaaatt gttccttgtg actcagagtt aaacggcagg ctcacaacct cttggtaaac
      301 ggtgttcaat cagctgaccc tcggtattag ctcaaaaaac ggcaaaatat gaggaactat
      361 ttttccgttt gtttctctaa tactcaggtc aaaacgctga tttcacaacc tctttgttca
      421 tcaaaagata atattgtctt ctaacaagtc catattcaaa ataacgatat gatggtcttt
      481 aacggtgata ataccatctt ttttcagttg ttttaaaatt ctgtttacac tgctagcagt
      541 tgagatgcca caaaatttgg cgatttcttc attcgtgatc gaaaaatcga tcagcatccc
      601 ttcttctgtc cgcacaccga ataaatcata taattcgtaa agttgcgtac aaacagctcc
      661 cagctttccg tttaatagca tttgctgcat ttttttcatc gaataaagca gacgatagcg
      721 gtaatactct tttacatagt gttgtagctt tgggtcttgg ttgatatttt gccaaaagcg
      781 cacacgattg attcgataaa actctgcata ttctgattca actcgaatat tatacggcga
      841 atcgatgaat tgtgaatatt cgtcttttaa aagagagacg atttcaagat ctttgatata
      901 gcgaaggtta aattctctcc catcatttga aataacactt gcttttaccg ttccctcttt
      961 caagatatac gtatgggaat cttccatccc ttcgaatgtc aaatatttat gatatccttt
     1021 gcgtataatc ggaaaatcat ttttatccaa atattccttt aagactctac tatccaatga
     1081 tgctccccca tccaaacttt catctaaaaa gatcatacag tactttaaaa ctttttaaag
     1141 tccaaaggta ttttactaat gatattaaca tttgttaagt acctttttcc atcacttatg
     1201 cgattttttt cctttttttt attcgttata ctgcagaagt aaaatttttt aagaatagag
     1261 ggaaaaaaca tgaattactg gatgaacaca atcattaatc gattagaaac agcatatcaa
     1321 acaagatttg atatgaaagc ttctttagtc tttttaaatg atgcgtatca aaactcgatc
     1381 gaattgatca aagcagtgga tgagaatcca acaaacgaat gcgaagaatt tttaaatctg
     1441 tttatgtcta caagagattt atttattcgc caacttgttg atcgctatcc atccaattat
     1501 cacgatgtag aagttcaaat acaaaaatta aaagcatatt cagcttaagg ggaatgtata
     1561 acatacatgg aaaagaaatt atttaataaa tattttattg gaatcacatt gatcaatttt
     1621 attgtctacc tgatttatta tctgttgatg gtcatcatgg cagtcattgc gcaagacacc
     1681 ttacacgcca gcttgagcca agcaggtttt gcttctggga tctatatcat cggaacattg
     1741 ctggcacgct tattcatggg gaaacagtta gaactatttg gtcggaagtt taccttaaga
     1801 ggcggcgcga tcttctatct cctttcaaca ttagcatatc tttatacgcc aactatcggg
     1861 gcattgtatt tagttcgatt cttgaatgga ttcggctacg gtacagtttc tacagctaca
     1921 aatgctatcg ttactgcata tatccctgca tctaaaaaag gggaaggcat caattattat
     1981 ggattaagta ctagtttagc tgccgctgtt gggccatttt taggaatgat tttgctgaat
     2041 atgactgatt ttcgtttcat tatctggttt tcaattgtac tggtcttctt tgttacgatt
     2101 gcctgccttg tctttcctgt aaaaaatatt ccattatctg aagaacaaaa aatatctctt
     2161 cgctcatgga atatcaatag ttttattgaa aagaaagcac ttttcattac aggaattgcc
     2221 tttttgatgg gtctttctta ttcaagtgtt ttatcatttt tatcttctta tacaaaagta
     2281 atccacttag ttgctgctgg gtcatttttc ttcgtcgtat atgctttggt catcacattt
     2341 acacgtccat tgactggaag gattttcgat gtcaaaggag aacaatacgt gatgtatcct
     2401 agctatttat tcttaacagc aggattattt ttactgagtg taacgacgaa tagtgtgaca
     2461 ttgcttatct ctggagcatt agtcggccta ggttatggta cgtttatgtc aaatggacag
     2521 gctgtttgtt taaaaatcgt ccgcgaacat cgaatcagta ttgctttatc tacctacttt
     2581 attggtttag acctaggctt aggcgttggt ccttatttga tggggatgct aaaatctctt
     2641 acttcattta gaggattgta tgtgattgcc ggagtcattc cattgatatg tacagcactc
     2701 tatcttgtta atggccgaaa acatagtcat gaagcagagg gcgaattgat tgaatcattg
     2761 aaaaatgaaa tttgatcttg atgaatagat aaaaaaaacc gttcagatct gaaaataatc
     2821 tgagcggttt tttgagtaaa aatagtttat gattattctt aattaaacat ctatttattt
     2881 ttaaagcttt catttatcga taagaatagt ttaactgttg atttattcca ttttccgttc
     2941 atctggtacg atgccttgac ttagcaacca cttgtggaag aaccattctg ccacaccgat
     3001 caatagagca ggaatcaata ctttcatcca aatatcgact gtatcattca taaaatatag
     3061 atagagccac aagataactg cagctgaacc agcatctgcg atcgtcgctg cgatgttccc
     3121 tactttacgt aagatcaaca gatcccctag cacatagatc atgactacaa taattacccc
     3181 aacaatcgtt gaatccataa agctaacacc gtataaacct gtcagcacga cccacagaat
     3241 cgcccagatc atgattgcct tcactaccaa cgccttcaca tgtttcattt tctgcactcc
     3301 tttctcctgg ataaaaaagt aagattatct aacaagataa ccttttcatt attataccat
     3361 cggctgagag aagcgagcaa agataaggtc ctatctaaaa atgaggaagc cacttagaac
     3421 attcacgtaa taatttatcc gtacagacat tcgatatggt gttcctttac tttcgcatac
     3481 tgttcttttg tcagttcttt acttgtcacc agataatcga tttcatgaaa agcaatggct
     3541 tgatgcatga atttatgtgc aattttttgc tgtgtaacta aaacggcaag ccggtctgat
     3601 tgttttctaa aagctttttt gaccattgcc tctccttcat gagtttctgt tactccttgg
     3661 ctgaaatcta gcccgcgaca actcattatc gctaaatccg cataatatga caatgcatcg
     3721 ttataggctt ttgaaccgtt gattgttgct cgtttcggaa caattgcccc tcccaataca
     3781 gatacttttg ccgttgtata ttcactcaac atagcagctg tgacgatgcc attcgtaatg
     3841 atctgcaaac catcaaatct tgctaggttt ctgactaagt gtaaagaggt tgtactggaa
     3901 tccaagaata agaccatatc atctcgaatc aaagaagaag ctgtatctgc aatcttacgt
     3961 ttttctgttt cttcttctaa tttggtgatc ttcatcaggt aaggcacgtc aatttttcga
     4021 ttgtcaataa gcatggcgcc accgcgaact ctacggatca atccactttt ttccagaaaa
     4081 acaaggtcac gtttaatcgt ggcttcgcta taatttacta actcgatcaa atcggtgact
     4141 cttgcaaatt ggttgttttt tagataattc acaatctcct gctgtctatt ctccacttca
     4201 ttcaacataa aatcacccca tttactttat atagtaacag gaaaaaagag gttgtgacag
     4261 aagtgattgg cttcgagaaa taagaagaaa tttttcgaaa aaactacttc tgaacatcgt
     4321 gtgtggttaa gagggtatga caagactatt gtcataccct cttgaccaca catttttatt
     4381 tttagtataa actagccttg cctactgtgt tcaaaatttc cattttatgt ttgaccactt
     4441 cttgtacctt tttattagct gctggataaa ttgcattcgg ctcgtacatc gatggatttt
     4501 cactcaatat ttctctcaaa gcattgaaaa agacgctttt aagatctgag ctcaaattca
     4561 ctttggcaac tccgtatttt actgcttcgc tgacttctgc gtccggatta cctgaaccgc
     4621 catgtaaaac aaatggaaga tcgatttgtt ggttcaattc tttcagtaag tcgatattta
     4681 attttggagt tctgtttttc ggatacaagc catgcgctgt tccaattgct acagcaagtg
     4741 tatcgattcc tgtttctttc acaaaaatct tcgcttgatc aggatctgta taaatgattg
     4801 tttcagcacc tccttcagca gaaccattat tcccaatcgt tccaagctca gcctccactg
     4861 agacatttac cgcatgagct aacgcaacca cttttttcgt aatctgtaca ttgtcgtcga
     4921 atgatttcaa agacgcatcg atcatcacgg aagaatagcc gtttcgaatc gcccgtaaga
     4981 catcttctat cgtaccgcca tgatccaagt ggataacgat cggcagttta cttgtataag
     5041 cataggctct tactgccgca acaaactcat cacttaaata ggcgatttca tcaggatgaa
     5101 tttctaagat tactggtgct tctaatctct ctgcttcttc gatgattgct ttcatcatat
     5161 catagctgca aatattgaag gctggtactg caaattgatt ctctttagcc actttcaata
     5221 actctttcat tgtatataac attacgcttc cacctcattt gttagatttt catttttcgt
     5281 ccacttgtct tgttttttct ctttcactgt ttttttcaat agtccaagca taaaggctgt
     5341 agtgactgta cctgatgcaa ttgccaagac atacataggt aaattgttca taacatttgg
     5401 aattagcatc acccaaatcc ctccatgagg tgccattgaa gtaactccta ctgccatgga
     5461 aatccctgca gcgactgctg aacctgtcat caaactaggt atcacgcgga tcgggtcaga
     5521 taccgcaaac ggtatagcac cttctgtaat atacgaagcg cctaaaatcc agcatgattg
     5581 acctgaagtc cgttcttctt tggtaaattt atgtttgaat aataaagtgg ctaaagcaat
     5641 acctagggga ggtgtcattc ctgcagccat acaagcagca atcggtgcat ttactccagc
     5701 tgacatcaaa ccgatcgaga aagtcgaagt cgatttattg atcggcccac ccatatcagc
     5761 tgccatcatg atcccgataa gtaatccgaa caatagcccg gatgtatttc ccaagctatt
     5821 cagccaattt gtcaaagcat ccaacaccca tgtgatcggt tgttcaatca caaataccat
     5881 caaaagccca ataattaaga tcgataaaaa ggggacgaca atcagctgat aaatagcaga
     5941 aaattctttt tttacgctaa ttttatttgc cagaaaatca cagatatacc ctgctagcac
     6001 gccaccaatc attccgccaa gaaaacctga accacctgta gaggccagta atccggcaac
     6061 aattcctggg gcaaaacctg cttttccagc aatcgatgta gcaatccccg cgcctaacgc
     6121 aggaaccatc atggcaaacg ctgtatctcc tccgatcctt gaaaatgcag ctgctaacac
     6181 attatagtct gctgagttgg gatcagccgc tgtaatccca aaggcaaaac tcagtgcgat
     6241 gatgattccg cctgcgatca caaatggaag catgtaattc acaccattca tgaaatgatt
     6301 atagattgtc ggctttttct catttgcagc tggttctttt tcattagaca caacgaatac
     6361 gccaatatct ctcaatgctt cgtctattac tacttgcggt tctttgattg ctcggcttgt
     6421 agagacacgc tttacttttt tcccggcaaa tcggtccaat tcgatttctt tatctactgc
     6481 aagaatgatt gcatctgcct ctttgatttc ttgttcagat aactgatttt ctgtttttac
     6541 accttgtgtt tcgaattttg cttgatggtt tagatttctt gctgttactt ctaatttttc
     6601 tgccgacata taagtatgag caattccagt cgggcaagca gttacaccaa cgattttcat
     6661 gattattttc ctcctttttc ttcactatcg atactcggac aaagactcta ctattttcat
     6721 tcttgactaa tctgtctgat gatatctgct ggcgtagtgg cttcttttat tccctttcta
     6781 aaatctgcat tcatcaatcg tctggagagt gtgctgagaa tctctagatg catatctgct
     6841 gatttttcag gaactacgat ggcaaaaata tattcaattg gcatttcatc tatcccgcta
     6901 tagtccgtta atttggctgt atgaaaaaaa cacagtgctg gttttgtcac atatttgctt
     6961 tttgcatggg gaatcccaaa tccatcttct attcctgtgg agatctcctc ctctcgtttg
     7021 aatagtgcct taacgacttt ttgaacattt cttaccttat ttgttttttt caacacatcc
     7081 cctattcgct caaataatga tccttttgaa tctatcgatg gatcgaaaac aatcagttct
     7141 tctgcgatca attgatcaaa cctcataaaa aacctctccc ccacaaaaaa tgttaacgtt
     7201 ttcttggaac tgaggtcagt atagcatcgc tagctgtacc gttcaatatt atgaatgaac
     7261 agaggaaaaa gacccatcat ccgcgtgtat aagtcattaa aatgaacgat ctagctcaca
     7321 aacaatcgca agtctataac aaaacaaaaa gccttccttg aaaggaaagc ttagcttcta
     7381 attttaggta aatggttttt tacttcgaaa taacccctct tcatttcgtt aatataaggt
     7441 gtttttatca agtggataat taaaactata tactagtttt tcattgtttt gtgcattatg
     7501 atcctacgac tttttcagca tcaaacgaag ttttaaattg gcaaaaaaca taaaaaaaca
     7561 gactatccct atcagatagt ctgctaaacg ttgagttatc agcgttttta ttattccgca
     7621 gcgtttgcgt ctttgagacc gtattttttg ttgaaacggt ccacacgtcc gtctgcttgt
     7681 gtgaattttt gacgtccagt gtagaatgga tgtgagtcag aagttacttc gacacggatg
     7741 actgggtatg tattaccgtc ttcccattca actgtttctt gtgaagtttt tgttgaacct
     7801 gacaagaatt tgaaaccagt tgttgaatcc atgaatacta ctgggtggta atctggatgg
     7861 atgttttctt tcatgatttt ttcgctcctt tgccctgctc catttgctga accagagttg
     7921 atttgtcgat ttacaacatt aacatcttaa catgtttcag tcaaggttgc aattatcttt
     7981 tcagatttct ggtcggattt tttttaccaa aggagacatc ttgaaattct ttgaaaaatt
     8041 gctgattgtt ttttgtttta cgcaaaaagc ggatcagttg ttccgtatat tctaatgaat
     8101 ctccagtcat attttttcga agtttccaaa tttcttctaa ttcttcactt ggcatcaata
     8161 attcttcttt tcgggtacct gattttttga tatcgatggc tgggaagatc cgacgttcag
     8221 ataattcacg tgaaagttgt aattctagat ttccagttcc tttgaattct tcatagatca
     8281 cgtcatccat acggcttcct gtatcgacta aagcggtcgc taaaatcgtc aaactgccac
     8341 cttcttcgat gtttcttgct gccccgaaaa atttcttagg tttatacaat gcggctgggt
     8401 caatcccgcc actcaatgta cgtccgcttg gtggaacgac taagttatag gcccgagcaa
     8461 gtctagtaat actatccatc aagataacga catctcgttt atcttcgact aaacgcattg
     8521 cgcgttccaa tactaattca gaaactcgag tatggttttg cggctgcaga tcaaatgtag
     8581 aagataccac gtcgcctttc acgcttcgtt ctagatccgt tacttcttcc ggtcgttcat
     8641 caatcagtag aacgattaat tctacttccg gatagttttc ggtgatacca tttgcgattt
     8701 cttttaatac agaagttttc cctgcttttg gcggtgcgac gatcaatcca cgctgaccaa
     8761 aaccgattgg agaaaagata tcgatcattc gggtagatag tctttgcggt gttgtttcca
     8821 gttgaagctg tctttgcgga taaagaggtg ttaaggctgg aaaatgcgga cgttcttttg
     8881 cttcttccgg atcttttcca ttaacgcttt ccacgtgcat caaaccataa taacgttccg
     8941 attctttagg tggacgggct tttcctgcca ctttgtcccc atttctcaaa ctgaatcgtc
     9001 tgatttgtga ggcagaaata tagatatctt ctgcacttgg tccataattg attggccgta
     9061 aaaaaccgta accatcttga ccaacgatat ccaatattcc ttccatataa taaaatcctt
     9121 gtttctctgc ttgtgcacga atcacagcta gagataattc ctttttattc atcttactgt
     9181 aataaggaat tttaaattct ttggcataac tataaacttc ttttaacgtt ttgttctcta
     9241 gttctgccat tgtcaaataa tcgctcattc agctcccact tcctctatca tttcaattga
     9301 tgcccctaag gctgttagtt tctcgataat atgatcataa ccgcgtaaga tataatctac
     9361 attgtaaatc gtcgttgtcc cttctgccaa tagtccagca atcactaaac aagcacctgc
     9421 ccgaagatca gaagccacga cttctgtgcc gtgaagttta tttggaccat tcacgatgat
     9481 catatttcct tccacggtaa tatcagcgcc cattcgtgct agttccggca catggttcac
     9541 acgtttcgca tagatcgtat cgatgatttc tgaagtgcct gtagtcatca atagtaacgc
     9601 agtaagtggc tgctgcagat ctgtggcaaa tcctggataa ggataggtca tgatgtttgc
     9661 gggttttaat tctttcgagg ggtaaacttc gatttcatct tcgctgattt tcatatggac
     9721 accaatttcc tgcaattttg ctataaagct ttccaaatgt tcaaagatca catttttcac
     9781 tttgatacca tttcctactg cagctgctaa tgctagatag gttcctgctt cgatgcggtc
     9841 aggaatcatg aaatgccgac agccatgtaa tgtttcgact ccttcgatac ggatcacatc
     9901 tgtacccgct cctcgaactt ttgcccccat attattcagt aaagttgcca catctatgat
     9961 ttccggttct cgtgcagcgt tttcaattac tgtctgtcct tttgctttta cagcagctaa
    10021 catcacattg atcgttgctc cgactgaaac cacgtccatg aaaatccgat tgccacgcaa
    10081 tcctttattt tctgtccgta aatacatggc accatgttca tttgtcactt cagcacctag
    10141 agcttcaaat cctttgacgt gtaggtcaat cggtctaggg cctaaataac agccacctgg
    10201 caggcctact accgcttcgc caaatttacc aagcagtgtt cccataaaat aataagaagc
    10261 acgcaaacta ttgatttttc cgtgcggcat cggaatcgat acgacttctc gaggatcgat
    10321 ttctagtatg ttgttggaaa aatggacagt tgcgcccatg atctctaaaa tttcaattaa
    10381 tgaatgaaca tcttgtatgt ccggcacacc ttccaagatc actggggaat cagctaagat
    10441 tgcagctgga atcaatgcga ctgcactatt ttttgcaccg ctgatcgtta cttcaccagc
    10501 taaaggtcgg tttcctttga ttacgatttt tttcatctgt ttccaccttg tttattaatc
    10561 ttttttcatg gatatgcttg tattttatca tagataaaaa aaagaaacga gcatggtctg
    10621 ccgttttaag taaaaaagaa tggagagcga cttcaaaagt cgttctccat tcctatatat
    10681 cgtatctgtt atgtggatgc ttacgctttg ttagctgaac cgaaccagtc gatatgagat
    10741 ttagcatctt caacgattgc tgctttacct ggagctaata atttacgagg gtcgaatcct
    10801 ttaccttctt tatctttacc agcttcgata tatttacgag tagctgcagc aaatgataat
    10861 tggaattcag tgttaacatt tacttttgag atacccattg agatagcttt ttcgatttga
    10921 tcttgaggaa tacctgatcc gccatgtaat actaaaggca tgtctggacc tacagcatca
    10981 gcaattgctt gtaagtggtc aaaagctaat cctttccagt tttctggata ttgaccatgg
    11041 atgttaccga taccgcaagc taagtagtcg atacctgtag caaccatttg tttgcattct
    11101 tcaatatcag ctaattcgcc gttaccgatg attccgtctt cttctccgcc gattgaacca
    11161 acttcacatt caactgagat accttttgca tgtgcttttt caacaacgtc tttagctaat
    11221 ttcaagtttt cttcaaatgg tagatgtgaa ccatcgaaca ttactgaagt atagcctaat
    11281 tcgatacatt ccaaagcagc ttcgtaatca ccatggtcta agtggatagc aactggaaca
    11341 gtgatgttca ttgcttcaac taaatcagtg attaaatctt tacagatttt gtaaccaccc
    11401 atgtatttag ctgcacccat tgatgtttgg ataagtactg gtgcttgttt tgcttcagcc
    11461 gcttcaagga ttgcttgagt ccattccaag ttgtttgtgt tgaatccgcc gacagcgtaa
    11521 ccgcctttac gagcagcttt taaaaattca gctcctgata ctactggcat aataaaattc
    11581 ctcctaagtt ttgtaaaact aaatttgtta agacaattct taaccaacga ccctatttta
    11641 ccaaacattt cggtagtttt ctactaaaat caatgaaaat gaaaattttc aagaagtttt
    11701 ttgcaaaaaa taaaatatcc aatagcgctt taatcgaaaa aagtcttttg ctttctatct
    11761 tttttcctac aaataataac aaatcagaaa aagagaaaag tgacaagaaa attgcttatc
    11821 cccttctctt gctacttttc tctttctatc aagttcaaaa attattttgt ttcgtgatct
    11881 gctaatgatg ctccgacaaa tgctttgatt aatttttgcg ggcgatttgg acgagaaatc
    11941 aattctgggt ggaattggca tcccacaaag aattttttct ctggcagctc tacgatttct
    12001 actaaacggt tatctggtga gacacctgaa aagactagcc cttgttcttc aaacaattga
    12061 cgatatttgt tattgaactc atagcggtga cggtgacgtt cttgcacaac atcggctcca
    12121 tcatatgctt cagccgtctt cgttcctttt ttgattttac atgggtataa tccaaggcgt
    12181 aaagttccac ccaaattctc gatgttttcc tgatcagcca ttaaatcaat aatattgttt
    12241 gctgtatctg gattcgtttc agctgatgac gcatcttcta atccaacgac gttacgtgca
    12301 aattcgacac aagccatctg cataccaaga caaataccta aaaacggaac gtcattttcg
    12361 cgagcataac gaatcgcttc gattttccct tctactccgc gatcaccaaa tccaccagga
    12421 accaagattc catctgcgtc tttcaaacgt tcttctacat tttctctcgt taattcttgt
    12481 gctttgatcc aatcgatctc gatgtctgaa ttataggcga aaccagaatg tttcaatgct
    12541 tcaactactg agatatatgc atctggtaac tcgacatatt taccgacaag cgcaatccgt
    12601 acttttttct tcaagttcaa gacacgttct tctaattctt tccattctgt catgtctgct
    12661 tctggtgtat ctagttttaa atggtcgcaa acaatttgat ccattccttg tgcttgtaaa
    12721 actaatggga tggagtaaag tgtatctaca tctggcgact cgataactgc ttctggttcg
    12781 acatcacaaa attgtgccaa tttgtttttc acgctttgag aaacaggttg ctctgtacgt
    12841 accaccaaaa tattcggttg gatacctaaa ccacgtagct cttttacact gtgctgcgtt
    12901 ggtttagttt tcatttctcc agcagctttc aagtaaggaa tcaatgttgt atggatatac
    12961 ataacattat ctgtaccgac atctgctttc atttgacgaa gtgcttcaag gaatggcaaa
    13021 gattctatat cccctactgt tccccctact tctgtaatga tcacatctga atcagtcatt
    13081 ttagctgctc gcatgatttt ttctttgatc tcatttgtaa tatgaggaat aacttgaaca
    13141 gttgctccca agtattcgcc cttacgttct ttacgcaaaa cttcagaata gatttttcct
    13201 gtcgtcacgt tggagtattt gttcaaattg atgtcaataa aacgttcgta gtggcccaga
    13261 tccaaatctg tttcagcacc atcatctgtt acgaatactt ctccgtgctg atatgggctc
    13321 atcgtccccg gatccacgtt gatgtatgga tcaaattttt ggatagttac ttttaagccg
    13381 cggtttttca ataagcgtcc taaagaagct gcaacaatcc cttttccgat tgatgaaacg
    13441 acaccgccgg tcacaaaaat atattttgtc ataagttcaa aaactccttt ttaatttatg
    13501 tgcaggaaaa gtctcagaca ataaacaaag ctccctattc ttcaataaga atagggagcc
    13561 gaaatttctg taaacttctg accctctaaa agggtgccca aggtgtataa tacaagctga
    13621 ctaagggaaa gtcaagtact caaatgaata ctatccgctt acaatttttt ctttttcgat
    13681 atcctttgag aaattatttc ttaagtcctt tatgagtgca aaaaaaattt aacccacata
    13741 ataagcttga tataaacata gctaacgtta aacctaagca aatcagaaaa tcgttactga
    13801 aaaattttaa gtgaaataat agataaaaaa ataaaacaaa cattatgata gataatatcc
    13861 cacctaacaa agaactactt tttcctactt gcagcaacag tttatatagc ttatcgtaga
    13921 aacaatcttt ttctttcacc cttatttacc tcctttacgt aaaaaacgta gtccacagtt
    13981 ctcggatttt tggcatatct tttctattaa ataatatcaa aaacaaaaca attccactaa
    14041 ttttttcaaa gatgaccttt ttttcaacaa aagtgccttg tagggattca ttgaaggtaa
    14101 cgaatcacat aagtaaaaaa taaggagatg cgacaaaagt cgtgcctcct tatttctaaa
    14161 taaacggtgt tctcctgcca actcctcggt cacaagtcac aatatccatc aaacatgaga
    14221 agctgttttt gaaattattt cttgtgattc ggagttaaat ggtaggctca caacctctgg
    14281 ataaacggta ttcaaaagcc agtttctcgg tattaagcca aatttatgca aaaatgtaga
    14341 aagccatttt cacaaaattt ttcttaatac tcgaaactaa acgtcttttt caaaacctct
    14401 tggtaaacgg tgttcaaaag cttgcatctg cggtaataag ttcagccaat tcaaaaacaa
    14461 gaaaagctgt ttttgcttgg ctattcttat tacttgttgc agggcagctt tttcacaacc
    14521 tctccactaa acggtgttca atcagctgac cctcggtatt agctcaaaaa acggcaaaat
    14581 atgaggaact atttttccgt tagtttctct aatactcagg tcaaaacgct gatttcacag
    14641 cctctaattc acggtattcc tgttttaata aagttctaga tattgttctc tttcccactc
    14701 ggaaacagtt tgtctgaatg ccgcccattc gagacgtttt gcttcaacaa aatttgagaa
    14761 gatatgttgt cctaatgcgt caatcattac attatcctta cgcaattctt tgatagcatt
    14821 atggatagtt gaaggtaagt cctggatatg tgcagcttct ctttcttcct catccattac
    14881 ataaatgtta cggtcaacag ctgctggcgg tgtgatctga ttacggatac cgtctagtcc
    14941 tgcttgcaac aatactgcca ttgccaagta tgggtttgca gatggatcaa ctgaccgcaa
    15001 ttccaaacgt gtggataaac cgcgagattc tggtacacgt actaatggcg aacgattacg
    15061 gccactccat gcgacataaa caggcgcttc ataacctgga acgagacgtt tataagaatt
    15121 gactgttgga ttgcaaacgg ctgtgtaggc acgagcatgt ttcagcaaac cacctaagaa
    15181 atgataagct gtttcactta gttccaattc accgtcttta tcatagaaaa catttccttc
    15241 atcattgaac aaagacatat tgcaatgcat accagaacca ttgatcccaa ataacggttt
    15301 cggcatgaaa gtcgcgtgaa gtccatgctt gcgcgcaatc gttttgacaa cgagcttgaa
    15361 ggtttggata ttatcacaag catctaccac atctgcatat ttaaagtcaa tttcatgctg
    15421 tcctggcgct acttcatgat gtgaagcttc cacttcaaag cctagacttt ctaattccaa
    15481 cacgatgtca cggcggcaat tttcacctaa atctgttggt gcaaaatcaa aataaccacc
    15541 tttatcattc aaggtcgttg tgatcccacc gtcttcgtct aatttaaata agaagaattc
    15601 tggttcaggt cctaaattga aagaggtaaa accaaggtcg cgcatatctt tcaatgctcg
    15661 tttcaaattc ccgcgaggat cgccggcaaa tggtgtccca tccggattat agatatcaca
    15721 aattaaacga gcaacttttc catgagcact ttcccacggg aagatcatcc aagtggagag
    15781 atctggatac aaatacatat cgctttcttc aattcgaaca aatccttcaa tcgaagaacc
    15841 gtcaaacatc attttatttt ctaatacttt gtcgatctgg ctcactggaa cttctacatt
    15901 tttgatcgta cctaagatgt ctgtgaacat caatcgtaaa aatcgtacgt tttcttcctc
    15961 aatgattcgt ttgatttctt cacctgttat ctgtttcttt accatggtat ccctcttcct
    16021 tttttaattt attcagtcaa agaattgtct ttgcaatcct tgcgactgat aatgacctgt
    16081 tttgcttaac ccaccttgcg ccaaaatctc atcacgaaaa atttgtcgaa cgtcatgatc
    16141 tgtcaacggc ttcttgtttt ttgcttcttg ttttttcgcc tgtgccattt cgtatacacg
    16201 tttgatccca gccatattca atccctctga aagatagtct ttaatctcaa gcaacatatc
    16261 aatatcattc agcgaataca tacgtcggtt tccttcgctt cgttccggat gaactaaatc
    16321 ttgttcttca taatagcgaa tttgccgagc agacaaatca gtcagcttca taactgtacc
    16381 aattggaaat acggacatag atcggcgcaa ttccttttct cccatcagac gtcccctttc
    16441 gttttataag ttggctaaag tgtaccaatt aaaaaaaata ttgtcaactg catatgttag
    16501 gttttctaac atgagatctc tattttttat aaaataacaa aaaaataaga acacaaaaaa
    16561 ggtatctagt tgattttcgt accagatacc ttttattttt tattatactg tactatcctt
    16621 tattagtgtt tttatt
//
LOCUS       DAFBSV010000062        16526 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.063, whole genome shotgun sequence.
ACCESSION   DAFBSV010000062 DAFBSV010000000
VERSION     DAFBSV010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16526
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.063"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(142..417)
                     /locus_tag="LLB18_001927"
     CDS             complement(142..417)
                     /locus_tag="LLB18_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBK5244924.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(660..1970)
                     /gene="der"
                     /locus_tag="LLB18_001928"
     CDS             complement(660..1970)
                     /gene="der"
                     /locus_tag="LLB18_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBK5244925.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(2152..3381)
                     /gene="rpsA"
                     /locus_tag="LLB18_001929"
     CDS             complement(2152..3381)
                     /gene="rpsA"
                     /locus_tag="LLB18_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HBK5244926.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(3516..4196)
                     /locus_tag="LLB18_001930"
     CDS             complement(3516..4196)
                     /locus_tag="LLB18_001930"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBK5244927.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(4245..4880)
                     /locus_tag="LLB18_001931"
     CDS             complement(4245..4880)
                     /locus_tag="LLB18_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBK5244928.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(4946..6349)
                     /locus_tag="LLB18_001932"
     CDS             complement(4946..6349)
                     /locus_tag="LLB18_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HBK5244929.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATKQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(6336..7367)
                     /locus_tag="LLB18_001933"
     CDS             complement(6336..7367)
                     /locus_tag="LLB18_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5244930.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESEVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            7398..7619
                     /locus_tag="LLB18_001934"
     CDS             7398..7619
                     /locus_tag="LLB18_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBK5244931.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(7784..8521)
                     /locus_tag="LLB18_001935"
     CDS             complement(7784..8521)
                     /locus_tag="LLB18_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HBK5244932.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(8674..10014)
                     /locus_tag="LLB18_001936"
     CDS             complement(8674..10014)
                     /locus_tag="LLB18_001936"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBK5244933.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(10251..11774)
                     /locus_tag="LLB18_001937"
     CDS             complement(10251..11774)
                     /locus_tag="LLB18_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBK5244934.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(12152..12763)
                     /locus_tag="LLB18_001938"
     CDS             complement(12152..12763)
                     /locus_tag="LLB18_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBK5244935.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(12886..13011)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(13093..13809)
                     /locus_tag="LLB18_001939"
     CDS             complement(13093..13809)
                     /locus_tag="LLB18_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBK5244936.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(13815..14384)
                     /gene="scpB"
                     /locus_tag="LLB18_001940"
     CDS             complement(13815..14384)
                     /gene="scpB"
                     /locus_tag="LLB18_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBK5244937.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(14368..15165)
                     /locus_tag="LLB18_001941"
     CDS             complement(14368..15165)
                     /locus_tag="LLB18_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBK5244938.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFGTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(15135..15506)
                     /locus_tag="LLB18_001942"
     CDS             complement(15135..15506)
                     /locus_tag="LLB18_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBK5244939.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(15525..16412)
                     /gene="xerD"
                     /locus_tag="LLB18_001943"
     CDS             complement(15525..16412)
                     /gene="xerD"
                     /locus_tag="LLB18_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HBK5244940.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
BASE COUNT         4645 a         3578 c         2798 g         5505 t
ORIGIN      
        1 taaaaattaa ataaaataca tgtgttttct atgtatgaca tacggattcg gaatctctgt
       61 ctcttattta ttccttttct gctaggaaat aaaaagaaaa gcacttgtag ccctagagcc
      121 acaagcgctt tttcaactgt cttatttaac agcgtctttt aatgctttac ctggtttgaa
      181 tgcaggtact ttgctagctg gaatttcgat ttcttcacca gtttgtgggt tacgaccttt
      241 gcgagctgcg cgttcgcgaa cttcaaagtt accaaaaccg attaattgaa ctttttcgcc
      301 gttagctaaa gcatcttgaa tagttgaaaa tacagcatct actgctgcag ttgcatcttt
      361 tttagttaaa tcagtagctg aagcaacttt ttcgattaat tctgctttgt ttgccatgga
      421 tagattcacc tcctccacaa gagatatgat agaaatatca tttagttaaa actttctgag
      481 tggtccagaa gtttaaaaag aaatattgat taacttcaat attctgttat cacgatatca
      541 tatgaaccgc ttaatagcaa ggtttttacc aattttcaca tgcttttttt agtcatagaa
      601 acgtaacaaa cgaaactgtc tttttctttt gaaaaaaaaa cgtcgatatg gtaaaatgcc
      661 tattttctcc tacgagggat aattcggatg gacgtccctt caaaagtaaa tgcttttctg
      721 atttgatttt ctaagaaacg ttcataagaa aaatgcatca attcctcttc attgacaaaa
      781 acgacaaatg taggtggttt gacagcgact tgtgtagcat aaaaaatctt caggcgtttt
      841 cctttatctg ttggtgttgg attgattgct acagcatcca taatgatatc attcaacaca
      901 gccgaagaga tacgaagatt ctggttcata cttacttgtt cgatcatttc aggcagacgt
      961 tccaaccgtt gtttagtcac tgcagaaaca aaaacgattg gagcgtaatc aagataccgg
     1021 aattcatcac gaatctcttg ttcgaaatca cgcattgtat tggtttcttt ctttacaaga
     1081 tcccatttat tcacgacgat aataattcca cgaccagctt catgggcgta acccgctact
     1141 cgcttgtctt gttcccgaat cccttcttca gcattcagta ccatcaaaac gatatcagaa
     1201 cggtcaatgg cacgcattgc acgcatcacg ctgtattttt cagtattttc gtatactttt
     1261 ccgcgtttac gcataccagc tgtatctatc attaagaatt tctgaccact ttcagaaacg
     1321 aagtgggtgt cgattgcgtc tcgggtcgtt ccttcaatat ccgaaacaat tacacgttct
     1381 tctcctaaaa tcgcattgat caaagaggat ttaccaacat ttgggcgacc aatcaaacta
     1441 aacttaatcg tgtcgtcgtc ctcttcttca gtctcttcag agaaatactt cactgcttca
     1501 tctaaaatat caccaatccc tagtccatgg cttcctgaaa caggataagg atcgcctagc
     1561 cctaaggaat aaaattcata gatatcgttt ctcatttctg gattatctac tttattgact
     1621 gctaaaatca ctggtttatt acttctgtat aaaattttcg caaccatctc atctgcgtct
     1681 gtcacgcctt cgcgtccgct gactacacaa atgattacat ctgcttcttc aatcgcgatt
     1741 tctgcttgat gcttgatctg atccataaaa ggttcatcgc caagatcaat tccgcctgtg
     1801 tcgatcacgc tgaattctcg acctaaccat tcaccttttg cataaatacg atcacgagtt
     1861 actccaggag tatcttcgac aatcgagata cgctcaccag cgatgcggtt aaaaatcgta
     1921 gacttaccga cgttcgggcg gccaacgatt gcaattgttg gatttgccat attatttcct
     1981 cctcacaagt ttccaatctc acttagttta acgaatgcat tgccaacttt caagcataga
     2041 ttgtcaatta aacgaagtat ttttattcct tattgaaata ctaatcgctt ttcaaaagaa
     2101 aaactgagac aaaagcagct gctttcatct cagtcacaga tacaaaatca attatttttc
     2161 agaatcatcg gttgcttttt cttctacttc ttctttcaac gcatcaccta aaatgtctcc
     2221 catagtaaat ccagtatttt cttctggtaa ttcataagac tcaacatttt ttggttcttc
     2281 ttctgaagct ggtttttctt ctaaagcttt gatactcaat gcaatacgat gttcttctgg
     2341 atggatctct aatactttca ctttcacttc gtcaccttca tgaagcactt catgtggtgt
     2401 cgcaatatgt ttatgtgaaa tttgagagat atggactagc ccttctactc cagggaacac
     2461 ttcaacaaag gcaccgaagc ttgtcaaacg tttaactgtt ccgtctaata ctgtgccaac
     2521 tggagctttt gtatcgattt ctgaccaagg tccaggctgt gtgtctttga ttgacaagga
     2581 aacacgttct tgttcaggat tgatagacaa cactttgaca tttacatcat cattgacagc
     2641 caatacatca cttggttttg ctacatgact atgtgaaatc tctgagacat ggactagacc
     2701 gtcaattccg cctaggtcga caaatgcgcc aaaatcagta agacgtgcaa cacgtccact
     2761 gagaacatct ccctcatgga tagttgaaag aatttctttt ttcttttctt ctctttcgtt
     2821 ttccactacc gctttatgcg ataagatcaa acgattttct gatggttcga tttcgatgat
     2881 tttaaagctc aatgttttgc ctttatagtc tgaaaagtct gcaacaaaat gatcttccac
     2941 cattgatgca gggacaaaac cacgtacacc gacgtcaacg actaaaccgc ctttgacaac
     3001 atttgtaaca ggtgcttcga tgaccttgcc ctcttggaaa tctctttcga tatcttccca
     3061 aactttttta gcatctaaac ggcgttttga aagtaggtag ctgccgtttt ctttatcttt
     3121 gccgatcgta ctgataacga ctaaatctaa tacatcaccg acttttacta cttcgctgat
     3181 atcttctacc ggcaaagttg ataattcttt tgccggaacg actccttcaa ctccagcccc
     3241 ttcgattccg acaatcactt gtttgtcttc aatgactaaa acttcgccct taacaacatc
     3301 gccaactttt acttcttgta cgcttttcat tgcgtcttcc attgactggt tgttctcttg
     3361 attttgatca aattctgtca taacacttgt cctcctaacc aacattctgc cgtaagtacg
     3421 gtactgtttt tagtttaatt gattattcaa aaaaaataaa gcgatttcgt tcgttttcct
     3481 tgaaaaaaca attgtttttc attttttttc ttaatttaaa aaagaagata accttttttc
     3541 aaaacaacag cttttattgc tgcaacgact tctggaatcg atttgccagt cgtatcgata
     3601 cgaacagcat cctctgcttg cttcagcgga gagacgtccc ttgttgaatc ataatggtct
     3661 ctttcctgta tctctttcgt cagtgtttca agatcagtcg gaattccttt ttcttggttc
     3721 tctttgaaac gtctttctgc acgctcactt acgcttgcta ctaaaaagat tttcacttct
     3781 gcattcggta atacagctgt cccgatgtct cttccgtcca tgacaacgcc accgcgttcc
     3841 cctatttttc gttggacagc aactaattct tctctgactt ttccatgtgc agagacttca
     3901 gaaacagctt ttgtgacatc tggttgacgg atttctaaag tcacatcttt tgatgctatg
     3961 aatacatgct gtccatcttc ttgttgcgaa aaagagatag gatacttttt gatcagcgaa
     4021 actagccctt cttcatctga aaaagataca ttgttcgtaa tagctaaata agttactgcg
     4081 cgatacatgg caccggtatc tgtataaata taattcaatt cttttgctaa tatcttggca
     4141 acggtacttt tcccagatga agcaggcccg tcgattgcaa tactgatttg tgtcatgata
     4201 taactccttt ttctcagaaa aaaagccgca aagcgcggct attattattt aattcttaat
     4261 tcttgaccag ggtaaagcat aaagttgttt ggatctaagc cattcaattc aaacaattga
     4321 tcagtggtga tccctgcacg ctcagccact tgttttggac cttcgcctgc ttgaacagtc
     4381 gttgttgaac cggctgcagc tgatgaagaa ggtgttgttt ctgctgcatt gctgcttgaa
     4441 tcccctgctt gataagttgc ctcacttgag gaagtcggtg ttgtctctgc tgcaatactg
     4501 ctttctgacg ttacacctgt atcttgagac acagtagatt cttccgcgat tgtactagat
     4561 tctactgttg aagtctcagt tgactcctct tttgttgtac ttgtagaact ttctactact
     4621 gatgtcgaag tttcagaaga agttgctgct gttgcattgt tgcttgatcc atttctgatc
     4681 cagaaataag cacctgctgg aatagcgata cataagacca gtaaaatcaa aaatagcgaa
     4741 agaaataatg tatttccttt cttttgttgt ctctgagaac ttcttgatga aacttcatca
     4801 tctgtatcgt agattggttg ttcccatggt tcttgtgttt cgttattttc tgtagattga
     4861 tgtctatctt ttctgctcac tgttttacct cctaaactct atcgtgtgta ttataccata
     4921 ggaaaaagtg tcttgtccta aaaaatcaat gttccatgtt ttttttaaat aaatttagta
     4981 aaatcgtttc ccaatgaagt tgttcagtct tagaaaaaag cttcctcttt ggcagaagtt
     5041 ctgcttttgc tccatcaata tcacaacaat tctgcggctt ttcggagagt ttttcgccaa
     5101 aataagctaa gatgaatttt ctgcggcagt tttcttcatt aatatagcga agcatctgct
     5161 gcaggcggaa ttctttttct ttttcctgac gtttgagccg ttccacccaa ttttctggtt
     5221 tttcagactg ctggatcagc tccatccatt ttttttgcag ctcatcaaag ggagcttgct
     5281 ttgtggcata ttccaaataa agctcaaaac tttgtcgctg ttctctagaa agttgattaa
     5341 agaaataatg gatacgttca tccccacttt gataaaaaag aattgctgca ctttcttcct
     5401 gatctctgcc tgctcgaccg atttcttgta catagttttc tagactgtct ggcaaatcat
     5461 aatggaccac ataacggata tcagatttat cgatccccat accaaatgca ttcgtagcaa
     5521 tgagaaactg cagctgattt tttacaaact gctgttgaag ttgtcttctt tgagctgcat
     5581 caagaccacc gtgatagtat ccaactgtaa aacgttccct gaataaatga tacaatcgtt
     5641 cgacttcttt ttttgttgca caataaatga ttgccgctcc ttgtgctctt tccatgaagt
     5701 gttcaagttc ttgttctttt tgctgcgttt tccgaacaaa aagcgagata ttttgccgat
     5761 tgactgattg tctgatctct tttggtggtc gatcaaatag tacatgacgt atatctcttg
     5821 ctactaaatc tgttgctgtc gccgttagtg ccagtgtgac cgggtttcct aaaagctttc
     5881 ggatttttcc taactgttga tattctggac ggaaatcaac tccccattga gacacgcaat
     5941 gagcctcatc tactacatat aacgcaatat tttgtttttt cagatgctct aaaagagaag
     6001 gattagtcaa catttcggga ctcaaaaaca aaaatttata ttgcgataga tgacggagga
     6061 cgtatcttct ttcagattgc gaaagtaaac tattgaaagc agctactcgt ttctcccctc
     6121 gtttttgtaa ttgcgtcact tgatcttcca ttagagaaag cagcggtgac acgatgatga
     6181 ccagaccttc cattaaatac cccgtcaatt gatagcaaag gctttttccc gttcctgtag
     6241 gcaaaatagc gagagtatct tctccatcaa gcaacgcctg aataatttct tcttggccgg
     6301 gacgaaatga atcaaatcca aaatattttt ttaattcatt tattaacatt ctgtatcgct
     6361 tcctttctca atagatagat ttgatacaaa cgaaattctc cataatctaa ttgtccatct
     6421 acattccatt cgctaaagcg ccactctcgc acggaatcct tatttggttc caaacgttcg
     6481 attgtttctg cagagagaat ccactcgtat ggaaaatcat caaaaaacaa ggcccactca
     6541 ataagatgat ctgttactgt tcctcttttt aaatgacgga ttgccatgat ctggtcaatt
     6601 gtctgaccat tcataaacat ctgcttggtg atcatcatgc tttgattgaa attttgctgt
     6661 aataatgaat cgatcaaagc gtgccaaagc gaatctggcc gtttttcgat ttgtgctaac
     6721 aaaaggtgga tacatctgct ttgttgcaga taaacctctg actcatcatt gttttttgcc
     6781 agctgataag gaagcagccc tgttcgctca tttccagata attggttagc taaaaaatct
     6841 gctgcttctt ctggtatctc cgaaaacagc tgcaccaaac tctcatacgc agtatcaatc
     6901 aaaatttcac gtggcaattg gctttcacta agccattttt ttagttggaa agtataaaaa
     6961 ggacttgtct ctgctggaag atagtcttga atacccgttg ccagattaga aattacttga
     7021 acagcaaatt taatgagccg ccaactagtt tcccctgttc tgccatagcg gtcaaaacgc
     7081 aaaccagtat gttctatttg atgttcggac aacatatcag cccctgcagg cgttagcttt
     7141 gcttcatttt catttatttc gatccaacct tgctgcgcaa ttttttgcaa aatttgataa
     7201 aacttatcct gcttcaattc tggaaaactg ttatggataa acaaaagttc gtgggtaaat
     7261 ccataaataa gtactgaagt cgttcgtttt cccacaagga gttggtaaag agaactaatc
     7321 cgcagcttgt gtcctgatga aaatagcgat aaaataaaaa caatcatatt attctcctta
     7381 agttaggatg gttagaaatg tcactactat gtaaacttgt acctgaacgc tgtattgcat
     7441 gcggtctttg tcaaatcgaa gcgccagata ttttcgatta tgatgaagaa ggaatcgttt
     7501 tatttgccca agaaccagag gctcatcaac agttcgtgat gccggaagaa gaaacatatg
     7561 taaaaaaagc gtatcaaaaa tgtccagttc gagcgatttt attagaaaat aaaatataaa
     7621 tataaacgaa actttaaaaa cgtacactaa gttctctaaa cttgaaaata agccgggatc
     7681 tgtttctctt gttccgtgaa atcccgactt attttgaaag attcatttgc tatctatagt
     7741 taattgacta gttttttcac ggaccctata ggacccattt atattatttc aactttttca
     7801 gccagttttc caatgtattg acgatcacag tttgctggtc tgcgttagaa atttctgcct
     7861 ctccatctcc tttttgctca ccatagctgc caaaacctcc atgatttccg ccattgattg
     7921 atacatactc tgttctttcc ggtaaatact gcttagcttc ttgataagct tcctgattca
     7981 atactttatc ttttgtcgcc gtgatcgata aaacaggaac agctgattct gtcaatgttc
     8041 cttttttgtc gggataactt gccatgaaga ataccccttt taaatgtttg tctgaatgat
     8101 tcttattgac ataacgactt gccattacgc cacctaatga atggccaccg atcacataat
     8161 cggaatttgg aaaatcttct ttgaccttat ccgctttgtt tccgcccatc actgctagat
     8221 caagtggcat tttgacaata gcgactgaaa agccgttttt tgctaaatct tgcgcccaaa
     8281 tactataact ttctggctct acgagagcac caggataaaa aataagtaat ggagactttc
     8341 catgattctt tttctctcct tcaaaaaata agtaatcttc tttgtttttt ccttctttta
     8401 ccaacacttg cgcttctgac gatggttcgt acgtattttg ctgtatatag taataaccgg
     8461 ctccaccgag taatcctaaa atgatgacta agccaattag tattcgtcta aatattttca
     8521 ctttctccca ccttttctat ctgagtgacc cctttttctt aatcaagtat gattatacct
     8581 taaaaaaata agagagaaat gcaaactttc cagcatcaaa taaaaaaaga cggaatatcc
     8641 atttgaatat ccgccctttt tgtatgttta tttttattta gcacataaac gatacacagc
     8701 ttctgcataa atttccattg ctttatacat actacttaat tcccatcgtt cattcgcctg
     8761 gtgcataaag tcaggagtat cagggaacat cgcaccgaat gccacacact ggttcatcgt
     8821 acgagcaaaa gtagcgccgc ctgatacaaa cggttcagtc atgtctccag taatatcgcg
     8881 atatgtcccc aatagatttt tcactaactc actgtctagt ggcacgtata atgaatcaag
     8941 gaagtcaaat tcttcataag tcaacccata tttttctgct gttttagtta atttagctac
     9001 taaatcatct ttcttgaatg taacagggat tctcatatct acaccgattt ttgtttgttc
     9061 tggtgtgatt tccaaacttg caaagttcat cgttagctcg ccggattgtt catcttctgt
     9121 tttgcccacg acagcttcac cagttgcatt ttcttgaact aattttccta agaaattgat
     9181 tgggccaaaa tcaaatactt ctgaaagagc aattgccaga cgagaaatag cattcactcc
     9241 ttgtgctgca tctttcgcgt ggatactttt accaagaacg acgatgcctt caccttgttc
     9301 ttcgaaatcg aattcgtgtt ttttcaatgc ttcttttact tcagaaagct tttctccaga
     9361 gtaaggagct gcatcaggaa caacattcaa cgctcctcca gcttttacag aaaactcgtt
     9421 cgttcctggt cctgtcaagt aagcttgcaa taagcctttt tctgcataaa ttaaaggaaa
     9481 ttcagcatct ggcgcaaatc cttgcgtaat tccttcttct ttttcgttat atttttctaa
     9541 acaacgccat aaattttctt catctgtacc aaagataaaa cgaatacgtg tcttgaattc
     9601 cacgccagca tcaatcaaag ctttgacggc atacattgcc gcaatagaag gacctttgtc
     9661 atcttgggat ccgcgaccaa ctaaccagcc gtcttttata gttggatcga atggttttgt
     9721 ttcccaatta ttttcgtccc ctgctggaac aacgtccata tgacacaaga taccgaataa
     9781 ttcatctcca gagccaatct ctgaataacc gtaatagcct tctggatctt taaatgttct
     9841 aaatcctagc ttttcactga tttccaatac tttatccaaa gcttcaatca cttttttacc
     9901 gaagggatgt ccttgtcctg aatctgcttc atctagtacg gaaggaattc ggatcaattc
     9961 gctcaatgat tctaatgctt gttcatgatg ttgttctgtc acaaattttt tcatgatatt
    10021 atcctcctaa tatgttaaaa agggtcatgt caaattcctc cgacacaacc tcttcttctc
    10081 aaataatgac gttttaagcc tgctccatca gcaagcagaa tgttcttaac aaatgatgaa
    10141 agaaaaaaca ctcactgaat ggagctattg acttgtccac gtgcttatcg atagccgttt
    10201 atcggtttct tcattcttat gatagacctt gtacctgtat ttgtctaggt ttagaacatt
    10261 gctgctacac ctaggatcac acagatggct acaaataata tcgcaattaa tttaccggta
    10321 aatttccacc acactgaaac atcgaaacga gcaattgcta cagcacccat tacgatagca
    10381 gatgttggtg taattaagtt tactaaacca gatgcagatt gataagcagt gattactaaa
    10441 tccttaccga cgccggcaaa ttcacccata ggtcccatga ttcccattgt tgcagcagct
    10501 aagccggaag ttgaaggaat caagaatgac atagggatat agaaaataaa tgtaataatg
    10561 atgaatacac ttgaagataa tgaacttaat ccttgttcgc cccaatgtaa gatggtgtct
    10621 gtgattaatc cattgttcat aaccacttgg ataccacgag caacagctac tacgattgct
    10681 acaccgatca aatcagaagc accagctaaa aattcagaga caaattcaga ctctttcatg
    10741 ccataagtga ttgctactac gatggacatt actaagaata acatagtaat ttctgggaag
    10801 taccagtcac ctaatggaag catgctttta cctagaaccg tacctagtac cggaaggttt
    10861 gttaaccagt ttgtcaatga ttcaaaaatc gtgaaattcg cattcaaggt tgtccaagga
    10921 atcaaactga tgatcatgat accaaaagta ataaagaaca atacattaac atgtttttgt
    10981 tttttcgtga ttacttcttg acgaccgatt gcttcaatat cgaaatgctt catatcttct
    11041 ttacgttggt tgtatactaa tgattttgtt ggatcttttt cgatctttga tgcataacga
    11101 tacacatata caatagaaat agctaacaaa ataacgaaca tcaagaatcg aagaccaata
    11161 ccttcaccca tcgaaatccc aacagcttgt gaagctacgc ctgttgcaaa aggatttacc
    11221 gttgaagcta gacagcctac ttgagaccct actaatacga ttgctacagc tactactgta
    11281 tcaaagccta cagccatcat gactgggatc agtaaagcat agaatggaat cgtttcttct
    11341 gccattccgt aagtagagcc gcctaatgca aataacagca tcaatactgg aataagcatt
    11401 ttttcttttc ctttgaattt cttcacaact gaagcaatcc cggcatctag tgcccctgtt
    11461 ttgttgataa tacctaaaaa tccaccaaca accaaaatga agaaagagat tgggattgca
    11521 gcaggtgttt ctttagttag ctcccccgct ggtacaccta gcatcccatt gattggcgcc
    11581 atgaaaatat cccacagccc ttgaggattt tgttgtactc gttcatatga tccagcgacg
    11641 atgttgcctg catcgtctac actatagtgc ccagctggta taaaccaagt aagtacagcg
    11701 attactgcaa taataataaa taagaccgta tacgctgaag gcatttgaaa ttttttcttt
    11761 tttgtttgtt ccatcttctt cttcctttct tttccgttag agacaacaat tttggctcta
    11821 atgttatttt atcaaaaaga gtatcagaac aaaaataata acacgcattt tgtaaaactt
    11881 ttgttcaaaa agttcgtttt tccctattcc ctcctctttt ttcaggtttt taaagctttc
    11941 ttctttttca ttgtagcgtt tccttttttt tataaacaaa cattttcgtc ttttaaaagg
    12001 agaagaattt cacatttgca aagaattgat tgatttttat gcataaatca aaaaaatact
    12061 caaaacaaac aaataaaacg tttacattat tgcatgtctt gtattttttt ccaaaaaaaa
    12121 agaccaagaa atttcttgat ctttttgata tttatttgac tgctgtatga cgttgttcga
    12181 actgatgttg ttttcgactt aaccatggaa gaagttgcgc atgcagcact aaaaagacag
    12241 cactcacgat gaatcctttg atcaagttga aaggaacgat cccaatcagt acatagtttg
    12301 ctaaagacat gcccagcatc tgtgttgcgt tcagccctaa aaacattaag taaagaggcg
    12361 taataacgaa ataatttgcg atactcataa aaatagttag agcgatggtt cctgtaatga
    12421 cacctaaaaa tttgtttctt cctttatgct gtttctttac actaaagaaa taataaatcg
    12481 ggaatgtaaa gatcgttgtt gataagaaac tagcagtgtc tcctaccaaa ttatccggag
    12541 aaaaacctgt agtcagcaga tgtaatactg aacgcaagaa cgctgttgca actccggccg
    12601 ctggaccgaa taagaacatg ctgatcaata ccgagatatc actaaaatcg atcttcaaaa
    12661 aactaaaagc cggcatgatc ggaaaagcaa aatactgtaa aactaatgcg atcgcagcaa
    12721 acatcgctac tgcaaccatt ttctgtacac gggtgttctt catttgaaat cctcctgtta
    12781 ggactcctct tcagcgaact ttttgacgtt tctctccaaa tgaaaaaact ctattttcca
    12841 gggaaaatag agttagagtt atttgatcaa gcgtcgtcaa ataagctcta tcttctttat
    12901 ccagactata ctgtcggtat cggaatttca ccgattcagc tatttttttg caaaataggt
    12961 cgtggactat aaccaccggt cgggaatttc accctgcccc tgaagacgaa ccttatataa
    13021 tttttgttta catattcatt atacatatct attcaaaaaa cgcaacatct aacacttata
    13081 aaaagtaagt gttcattttg agtggttcag caaactgctg acttcttttt tgttcagttc
    13141 acggtaatcc ccaggacgta ggccttgtaa agtcagatct ccgtattttt cacgttttag
    13201 tttttgcaca ggaagaccaa ctgcttgaag catatttttc acttgatgat tacgtccttc
    13261 gtggatcgtc aattccacga tactgtggtt tgtcttagga tccactgata aaatttggaa
    13321 tttagctgga gatgtttttc gtccttcgat ctttattcct tttgtcaaag gtgcaagcat
    13381 cgattttgta gcgatccctt ttacctttgc aacgtaaact ttatccactt catgttttgg
    13441 atgtgtcagg cgctgagcaa aatctccatc atttgtcagt agcaagatcc ccgaagtatc
    13501 gtaatccagt cgacctacag gatagatacg ttcttttacc atcggcaaaa gatccgtaac
    13561 aacttttctt cctttgtcat ctgcaacagc agaaataact cctttaggtt tgtacaataa
    13621 atagtaaccg tattcttctt gataaattgg gacttcatcc acttccacag tgtcatgttt
    13681 cccaactttt atccctaatt cccttacaac ttgtccgttt acttttacac gtcctgcaag
    13741 gatgaattct tctgcttttc gacgagaagt gatgccagcg tgggcaatta ctttctgcaa
    13801 tctctccatt acaattattc tcctttattc attccatcaa agaatagatc tggtgacacg
    13861 tcttcttcaa gtgaaatttc catttcttgt gtatcaggca gttcttctaa tgatttcaaa
    13921 ccaaaataat ctaagaagta gccagttgtt ccatataata tcggccgacc tggtccttct
    13981 actctacctt tttcttcaat cagtttatgg gcagctagac gctgtaccgc tcctgaaacc
    14041 tgaactcctc gaatctgctc gatttcagct cttgtgattg gctgtttata agcgatgatt
    14101 gctaaggttt cgacggcggc ttgagataat gtgtttgatg tcccttgcgc atatcgctta
    14161 agtaagggag ccagctcttt tttagtcgtt aatacataat ggctttccgt ttcaaaaata
    14221 tgcaaagctg agtgcgagtt ttgagtgtaa gattctttta attctttcac taaacttgtg
    14281 acttctgctt cgctgagatt taacagtccg cttaattctt cattactgat cccttcctcg
    14341 ccaacaataa aaagaagggc ttcaagttca cttaatttcg tcatgttcgg tatctcctac
    14401 tgctggataa agcataattg attcatagtt ttctttttgt tgcgcaatga tctgcccttt
    14461 tttcatcaat tctagcaaag ccataaaagt agtgacaact tcacttttag aaggtgactc
    14521 aaaaaaagaa tcgaaagtac agccatgcgc atttcttttt atacgctctt cgataaatac
    14581 cattcgttct tcgatcgttg tgtcatcggg cgtgatcgtt ttttccactt tttgagaaaa
    14641 tttcttacgt tctaagattt tctgcatggc acggatcaaa tcgatttttt tgacttgtcc
    14701 tcgcttcaac ggcttttcag catccgctaa cccatcgatg ttcataggtt cttttgtgta
    14761 ataaagactt cgttcctctg ctttttctgt cagtctttca gctgcatatt tatatttacg
    14821 gtattctaaa agctgagtga ccaattcttc tcgaggatct tcttcccata attcttcatc
    14881 gtctgtgccg aattcttgga caggaagcaa tgtcttgctt ttgattgcca tcaatgtagc
    14941 agccatcact aagtattctc ctgcaacagc tagctcgagt gttttcattg tatggatata
    15001 attcatatat tgctccgtga tcgtagcgat cggtatatca tatatatcga tttccatttg
    15061 ctgaatcaga tgaagcagca gatcgagagg accctcgaat acatctaatt taatattgat
    15121 ctccgtcaac tcattcactc tttcttcttt ttctttgcta gccattttcc aatgtaaggc
    15181 tctgtgattt cagttgcacg gatggagaca tccgggtact tttcctgtaa ttcatctaac
    15241 atttgaaagc ccatattctc accgcgataa gacggattca aagaaatgtc atggatgatc
    15301 agctgatcgt tcgttgccca gtaaatacca ataatccctt gaatgttggt tgaaccttct
    15361 ggcgtaaaga aaaaaagttc ataatcgtct tcagattcgt acgtatcaat ctccttcaac
    15421 aaagaagttt tacctgtcag tttcttatgg aaactcaata gtcccatagc aattttacgg
    15481 ttttctttcc ggtaatgtgt taacatcttc tcaccttcct atgactaagc ccttggaaaa
    15541 tgctgcttat aaacatccgt catccttttc ttcgtgatat gtgtataaat ctgagtcgta
    15601 gagatatccg cgtgacctaa caattcctgt actgtccgca aatcagctcc attttctagc
    15661 agatgtgtgg caaagctatg ccgcagcgta tgtggtgtta cttctttgta aatcccagcc
    15721 tctcgtacta actgcttcag atttttccag attccttgcc gagaaagacc tttcccatga
    15781 ttattgacaa atacatgcat ttcagatgcg tcctttacaa gtaatggacg tgcttcgtct
    15841 aagtagcgtt ccagccattg gatcgcataa tcacctaaag gaatgatccg ctctttatct
    15901 ccttttccaa ctgtctgtac cagtccaaga gaaagatgaa gatctcccaa tttcaatcca
    15961 atcaattcac tgacgcgcat cccagtagca tacatgactt ccaagattgc acgatctctt
    16021 atccctaacg tttttgtcgt atcaggtgct tcaatcagct tttctacttc tgtcagagtc
    16081 aatgtacttg gtaatttctg tgctttcttc ggcgtatcga tatgttgcat cggatcatga
    16141 tcagtgatac gctcttgccg taaaaactga tggaatcttc tgagacttga gatcatccga
    16201 gtaacagttg ctgtcgcttt tttttcttca tgcaacttct ccagaaaacg gatgactaaa
    16261 aagcgatcga catcctgcca tgaagcaatt ttctgctcct gtagaaaatg caagtactgt
    16321 tccaaatcac gttcatagct ttgtcgtgta ttggcggaca atccccgttc aatattcaag
    16381 tagtggagat aatcgttgat ttgctctttc ataataatcc ccctcatgcc tctctatcat
    16441 atcagatacc gcttcattct gatagtcttt ttccataatc tgagcaaaga aaaagccgtc
    16501 tagacactca gacggactgg tttctt
//
LOCUS       DAFBSV010000063        16507 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.064, whole genome shotgun sequence.
ACCESSION   DAFBSV010000063 DAFBSV010000000
VERSION     DAFBSV010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.064"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            184..1182
                     /locus_tag="LLB18_001944"
     CDS             184..1182
                     /locus_tag="LLB18_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBK5244941.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1294..1803
                     /locus_tag="LLB18_001945"
     CDS             1294..1803
                     /locus_tag="LLB18_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HBK5244942.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1833..2492)
                     /locus_tag="LLB18_001946"
     CDS             complement(1833..2492)
                     /locus_tag="LLB18_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBK5244943.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2494..3258)
                     /locus_tag="LLB18_001947"
     CDS             complement(2494..3258)
                     /locus_tag="LLB18_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HBK5244944.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3266..3943)
                     /locus_tag="LLB18_001948"
     CDS             complement(3266..3943)
                     /locus_tag="LLB18_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HBK5244945.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3980..5365)
                     /locus_tag="LLB18_001949"
     CDS             complement(3980..5365)
                     /locus_tag="LLB18_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBK5244946.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLIIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5575..5659)
                     /gene="ffs"
                     /locus_tag="LLB18_001950"
     ncRNA           complement(5575..5659)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="LLB18_001950"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5682..6197)
                     /gene="tadA"
                     /locus_tag="LLB18_001951"
     CDS             complement(5682..6197)
                     /gene="tadA"
                     /locus_tag="LLB18_001951"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HBK5244947.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6304..7161
                     /locus_tag="LLB18_001952"
     CDS             6304..7161
                     /locus_tag="LLB18_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5244948.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(7242..7577)
                     /locus_tag="LLB18_001953"
     CDS             complement(7242..7577)
                     /locus_tag="LLB18_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244949.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(7644..9014)
                     /locus_tag="LLB18_001954"
     CDS             complement(7644..9014)
                     /locus_tag="LLB18_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBK5244950.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQSQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(9092..9628)
                     /locus_tag="LLB18_001955"
     CDS             complement(9092..9628)
                     /locus_tag="LLB18_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK5244951.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            9937..11418
                     /locus_tag="LLB18_001956"
     CDS             9937..11418
                     /locus_tag="LLB18_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5244952.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            complement(11521..12228)
                     /locus_tag="LLB18_001957"
     CDS             complement(11521..12228)
                     /locus_tag="LLB18_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBK5244953.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(12307..12645)
                     /locus_tag="LLB18_001958"
     CDS             complement(12307..12645)
                     /locus_tag="LLB18_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBK5244954.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(12756..13718)
                     /locus_tag="LLB18_001959"
     CDS             complement(12756..13718)
                     /locus_tag="LLB18_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HBK5244955.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(13733..15064)
                     /locus_tag="LLB18_001960"
     CDS             complement(13733..15064)
                     /locus_tag="LLB18_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBK5244956.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(15072..15752)
                     /locus_tag="LLB18_001961"
     CDS             complement(15072..15752)
                     /locus_tag="LLB18_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBK5244957.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(15971..16450)
                     /locus_tag="LLB18_001962"
     CDS             complement(15971..16450)
                     /locus_tag="LLB18_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HBK5244958.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
BASE COUNT         4884 a         3442 c         2736 g         5445 t
ORIGIN      
        1 tttgcatact tcataataat aataacataa tacctaacct ctcgtaaaaa tactagattt
       61 gttttctttt atttttcatc actagataca ttctataact taccgtttcg atttcgaatt
      121 caaacatttt tgagaagcat tctcaattaa attctgctat agtgtgaaaa gggaggaatt
      181 tttatggaaa tctatgacat tacaatcatc ggtgcaggtc ctgtagggat gtttgccgct
      241 ttttacgcag gaatgcgcca agctaaaaca aaaatcattg acagtctacc tcaacttggt
      301 ggtcaattag caactttgta tcccgaaaaa tatatttacg atattcctgg gtatccagca
      361 ataaaagcaa gtgaattaat cgatcaatta gaaaaacaat taactacttt taaccataca
      421 ttccatttaa aagaagaagt tctctcgctt actcgtgaag acgaagttat cgagattact
      481 acaaataaag gcatccatta ttccaaagca gtcattttag ctttaggaaa tggttcattc
      541 cagccaagaa aattgaattt agataatgct gaatcatttg aaaaccacgg attggattat
      601 ttcgtgaatg atttgatgaa gtatgctgga aaaaaagtcg ctattgctgg aggtggtgat
      661 tctgctatcg attggacgtt gatgttagag cctattgcaa gcgaagttta cttgattcat
      721 cgtcgcccgg aatttcgtgc gcacgaacat agtgtatcac gcttgaaatc ttcatctgtc
      781 aacttgctta ctccctatct catcgatgga ttatcaggca ataatgggga actgacagat
      841 atccggttaa aaaaagtgaa aagtgacgag acgattgatt tgatgattga ttctctgatc
      901 gtcaattatg gattctcttc taatttagaa catctttctt cttggggact tgatagtacc
      961 agaaatgcca ttactgtaaa atcagatatg tctacttcta ttccaggcgt ttatgcagct
     1021 ggtgacatct gtacctatga aggaaaagtg aaactgattg ctactgggct cggtgaagca
     1081 cctactgcag tgaacaacgc tttacactat attaatccaa aggaacgaac tcagcctggt
     1141 cacagcacaa gcttatacga taaaaatctt cgtcctagtt gattttttat atctctttgc
     1201 atttcaagtt aaacccgaaa gcagtttctt gcattttttt catgttccgt taacatgaaa
     1261 tagagaaaga aaaaataaag ggggagcaat aatatggtcg tcaaaactga gactttagaa
     1321 gaaaaggcaa gagaactatt gaaggaacgt ggcgtaactg tagaagatat cgcacaactt
     1381 gtcatgtttt tacaaaaaga ctatatttct gatttgactt tggcggattg tactgaaagt
     1441 gtcaacagcg tgctaacaaa gcgtgaagta cataacgcca ttatcactgg aatccaatta
     1501 gatatattag cagaaaagaa aaaattgatg agtccgttgc aacatattat cgaagatgac
     1561 gaaggccttt acggtatcga tgagatccta gccttgtcaa tcgtgaatgt ttacggtacg
     1621 atcggcttta cgaattatgg ttatatcgac aaggtgaaac ctggtatttt aaaagaacta
     1681 aacagccacg atggcgttca tgtccatacc ttcttagatg atatcgtcgg agcgatcgcc
     1741 gctgctgctg ccagtcgatt agcacacaaa gaaccagaaa aaagaagtcg ccttactcaa
     1801 taattcaaca aaaaaagaaa gaaaacgtct atttagacga gttctttctt ttttgtttgt
     1861 ttcaagctat tttttcctaa gaaaagaaaa acagcaaaaa ataattctaa taatacaaaa
     1921 aataagataa agctatgcat gaaaaattct tctggaagta cattgatgat tggatcagta
     1981 acgggatcga ataaccagtc atcgttgttg aaaaacgttt catgaaaaag gataaaaaag
     2041 cgatcaaatc ctatcatcat gaaaaaaccg aaaacaactg gcagtaacat gccgatttga
     2101 aacggacgaa tcaaccgcca aagccgatca ttcttttgca aatatttgat aaacaaaata
     2161 ctcgggatca aagtgatgaa aaacacagca taatccacta aaaacaaaat tttcacttca
     2221 taaaagtgat gggctccgct agcagaaact gggaaatctg gcaagctgag gatggttttg
     2281 aagggattat tgagataatt cattaggtga tcaaaatttt tcagtaacgt ctcttgatct
     2341 aaagaagtat aatccaaaat ttgcaaatgt ccgatatcaa atacgtatag tggtcgaaag
     2401 ttgatcgtca caccaactgc cagactgatc agtgtcagaa ataggctgaa caatccagca
     2461 tattccatcc actgccatct cgaatttttc atattagaag ctccattcat ccagtgattg
     2521 tttcacatag gtagctggga taggcaaccc aggtacatct tcttcttttg taaaacctga
     2581 taaaacgagc aaagtatcta tattattgcg tatcccagct tggatatctg tttcatagtt
     2641 atctccaacc atgattactt cttctttttg cagccctaat acttcaacgg ctttatccat
     2701 aatgatggct tctggttttc cgatgtagat cggcggcgtt tgggttgctg tctctacaaa
     2761 agagatgact gaccctgctc caggaagaag gccgcgttca gtaggtatat tcttatctgg
     2821 gttcgttcca atgaaagtag cacctttttg aatagcaagt gttgctttaa ctactttttc
     2881 ataggtcaga taattatcta agcctaccac tacatagtca ggagcctctt cttcccatgt
     2941 aaatccggca gctaaaatca agtcaatcaa tcctgcttct ccgataacat agactttttt
     3001 cccttttcca tctgctttca taaaatcgat tgttgccaaa gtagctgtgt agactgtctc
     3061 tggagctaca tgaatgtcaa actcatctgc tagacgatta gctactgttt ctggtgactt
     3121 agtcgtgtta ttggtaacaa acaagaaagg taattttctt ttttgcaatt cttccacaaa
     3181 tcgtttaccg gccggtatgg gttgtgtccc acgataaatc gttccgtcta aatcaattaa
     3241 atatccttta tagtccattc atccactact cttccctttt tctgatcgta aatgctgttt
     3301 ttgttttttc tacttgttta ggttgttctt gtttttttac tttttcagag gtttttgctg
     3361 actctgtttt tcgattttta ataaccggtt ttttgcgatt agatgcgact ggtccttttt
     3421 tctcatcgat atacgcacga ttatggtttt ttttcttttt tcggcgctga gttgtctttt
     3481 cttttttacc gccgattctc tcgatgacaa aatacgcaca accaaaattg caatattcgt
     3541 aaagatagtc ttccaaggaa tcgattcgct gatctggatg cgcccgtcga ttatccgctt
     3601 ggaaaaatcc ttttaggcgt agttgttcat aaccccaatc tcctacgata taatcatatc
     3661 gggctagtac atcactgtaa cgttctccaa gcttttctgc attaaatcct tcacgataat
     3721 cggacacaag ccgataatgt ctttcaccta tcaaaaaatt actgtcatct aacagtgtca
     3781 ctagctcgcc tttgactttt tctgctttag gctcctcaac gatttcttcc aaagcagctg
     3841 tcagttcttc ggtgactgtt gtttcctgtt cagctgatga ttttttctta gcaatttctg
     3901 ttttatgctc aacgttctgc tgttcatttt gttttgcaga catgcgttca ccacctatct
     3961 tttttattat accttgtttt tatttgattg ggtagtgagc tttcaagtaa tctcctacca
     4021 cacttcggat aaattcaggg aacaaaaatt cattttttcc agcaatctca atcgttggaa
     4081 aaaatggaac aaacatcaaa tgatctacgg tagtaaaagt ataattttta ttcagatcga
     4141 ttggcttgtt cttccaaaag acttgatggt taatagaatc atatgtgatt ccattataga
     4201 ccatctgccc aaaaatctta ccgcgaaatc ccattccctt cataggatag ttacgtaaaa
     4261 agttacgatt tttttctatt tctaaaacta agcggatcag atcatttcca cccaatgtga
     4321 catttaacaa gtgcatcgga tgcggcaacg cagtgtgaag ctgatcctga ttgacccgcc
     4381 cttttggaat ttcagttaaa aacagaccac tgtttaatat tgctgcttcc gtctttcctc
     4441 gttctttcac cgcctcaaag gctacttgga taaacgaatg ctcattgaag atatctagac
     4501 tcagagaaaa tggcaaatct gctacttctt tttcttttaa taattcatgc ccacgttcta
     4561 gataactatt tatttcttgt tcatcttctg taaaagctgt cattgtttcg gtagggatgg
     4621 ctttggctga atgcttaagg atttttttct cttcatcgat gattaaatgg acttcaccga
     4681 catactgccc gtactttcca gcggctgcta tttggacatc attgattacg tgaccttctc
     4741 tgaataaatg atgggtgtgc gatcctaaaa taacatcaat tgctggtatt tcttttgcaa
     4801 tttggaaatc atcctgaatc ccgagatgac tcatcaaaac taaaacatcc acttgtgaac
     4861 gtaaatcttc gactaattct ggcaaaatat cataaggatt ccgtatgtcc cagccattcg
     4921 gattataagt aagcggaaat ggagcagtaa atgcaattag tccgattttc gtctggtgtt
     4981 tcgttgtaat gattttatat ggtttcgtcc atgccggtgg ctggagcgta tttttatcga
     5041 ataagttatc caggatgata tcaaactcag catgatcgta taaatgattc aactcttctt
     5101 tggaatttcc tacgccttca ttgtttccta tcgtcgctgc atcataacca acttcattca
     5161 tcagcaagat attttcctgt ccattcgttg cttctgacaa tggatgccaa cgatccacaa
     5221 aatcacctag atctactgca atcgttgtcg ttttttcttt cttttcgttt tctcgtttac
     5281 gttgatccaa aaaccttctg atccttggcc aattttctaa atgagaatgc agatcattcg
     5341 tatgtaaaat cactattttt tccatgtacc ctctcgcctc tctttatctt tatcatacca
     5401 taggcagctt tttcttccat tgaaacaagc tctatttcag agtttttcct gccttgaagc
     5461 aaattgtata agtacaatat tcgataaatc agtctggcta aaaaatcagg aacattcatt
     5521 tttacagtac tataaaaata aaaaaaacag acccgaaagt ctgttgtcgt ttcattataa
     5581 tcagacacat ggcggaacct gcttagtgct gcttccttcc agacctgaca cgcttcacaa
     5641 gcccaccatt gtcctagcct ttcggcaaag aatagtatac cttatttttc attcgttgac
     5701 cagtcttttt ttaatttctt ttttcgctgg cggagctttc ggaaaaagtc agtcaaaatc
     5761 atcccacatt cgtcttctaa aatgccacct tctacatatg cttggtggtt aaaccgctcg
     5821 tcctccaaaa gattcatcaa ggtaccggct gttccgcctt ttggatcata cgcgccgaaa
     5881 taaacttctg ctacacgaga caaaatcatc gcgccgctgc acataggaca aggctctaag
     5941 gtaacaaaaa gtgcagcatc ttccaagcgc cagcttccca ctttttcaca ggcttccttg
     6001 attgcaagca tttctgcatg tgtagtagca tcttgcgtgg tttctctaag gttatatcct
     6061 cttccaatca cttttccatc caatacaacc actgctccaa tcggaacttc atgaagcatt
     6121 tctgctttct ttgcttctgc caatgcaagg cgcatccatt tttctttttc tactgcatca
     6181 agatttgtat ttaccaatta cccttccctg cctttgtttt ttcttgtttt actttagcat
     6241 atgataaaaa ggctgtaact aacttttttt tctatggtaa aataaataca agaggtgaac
     6301 aagatgaaaa tggataaatt acttgctctt tacccacaag cacagaaaaa aaactctcca
     6361 gcatcagaag cggatatcct ttcttttgca attgatgatg cttttatctg gatcaaacaa
     6421 gattcattat ctcaacaaga aaccagcctt ttgaaagcgt tattccctgt aatcaacgat
     6481 caaaaaaaac acccatggta tcactatctt tttaaagatg cttcttgtgt tcaagaaaaa
     6541 agctttcgtt tgatccagct tcacgtcgaa tcaaaaggag aattcttaaa aaaagaatgg
     6601 caagatacta ttttggaatt atttcgctat tctgctgatt tcttttttta tacagacaca
     6661 gatgcgctct tagtcgaaca aataaaccgt gattatcttg atgctactga aatcaacggt
     6721 atttttctat ctttagatgc tgattttgat acgacaacgt ctgtattcgt tggttctttc
     6781 cattcacctg gcaccgacct cgtccctttg tttgctgaag aaagaaaaat ttttttaaca
     6841 gagcaaaaca atctttatac tcacagccgt actttttcta tgcaagatgt ggctttacat
     6901 tactatacaa aagatactgt aaaagatagt aagttgatca aaagttacat agaactgatc
     6961 aaacaaaatg aaatggaagt gatcattcaa gaattatgga atgaattagg caatgtcagc
     7021 tctgctgcaa aaacactgtt tcttcatcgt aatactctaa aatatcgaat cgaaaaattt
     7081 caagaacagt ctggtttcaa tctaaaaaaa gccaacgatt tactgttttg ctatctttta
     7141 ttgcttcatg aacataatta aagatagatt aaaggggttg tgacaataat tttgtcacaa
     7201 ccccttattt cgaatgaata gtgttcaaaa gctagtttct cttacatcat tttttcaaca
     7261 aaatgcatta gccggtcttt tacatcttcg gttgaatctt tgattgaatc accataaaca
     7321 gagattttct tttttcctga tttgattttt gctaacattc ccatcaaaga atccaagtca
     7381 ctatctgaaa gaccatctac gatttctagt aatttttcat ttccatcaaa tttgtcatag
     7441 acgaattttt ttactttcgt ccgagtagtc atatgatgga tcttttccat tacttttccc
     7501 gatacaacga ctgctgtcgc tacactggca gcggctgcta cgcttaatcc gattgttact
     7561 tttgttgatg ttttcataag tatcagctcc tttttatcta tctccatcat agcatagaca
     7621 aaaaaataaa cgaactaatc cactcagtga aatctcaatc ctttagggaa aaagttcttt
     7681 actgttcctt ttacttgttt cccaaatccg acaggtatct tatctaatac tagcaaaacc
     7741 catccttgat tcccatcacg ttgaaatgtt tctcctgctg tgtaagattg ccattccttt
     7801 tgagtgatcg gcaagcaagg tatattctct atcttttttg tagcaagcgc taatgcatag
     7861 ctaggttcaa atcgattctt tttgaaatct cctaaatgca aacctgtacg tacgactttt
     7921 aaaccatcga gagaaggggc taactcagga acttcccaaa gatggtcgtt gaacactaaa
     7981 agtcttccag tagcttcata atgaaaatca tttgaaaact ccgtccagag tttttcctgc
     8041 tcttttgtca tttgcacttt actttttttt cgtgtcttct tttctttatg catctgactt
     8101 tgtccatgaa aagtcagctt tgcaacaaaa tgtccttcac cctgatcttt atgaggccat
     8161 atacgtattg ttttttccaa accagctacg cttccccatt cagaacgtcc tgaactaacg
     8221 gattgagtca aaggaatctc ctcaatcgtt actggataat tttctacaag ccagctaatg
     8281 atctcttcat tttcttctgg tgcaaacgta caagtcgaat aaatcagttg tcctttattt
     8341 tttagcattt ttattgctga agacaaaatc tcttgctgac gtttttgaca gtatagcgga
     8401 gattcttctg tccactcttt tattgcattt ggatcttttc ggaacattcc ttctcctgaa
     8461 caaggagcat caaccacgat ccgatcaaaa aagcccgaaa aatgagggac aagttctgcg
     8521 ggtgcatgat ttgtcactat tgcgttcgaa actccccatc gttctatatt ttctgataaa
     8581 atcttcgcac gtttcggaaa gatctcattc gtcactaata accctttccc cttcatttga
     8641 gcagctaatt gggttgattt accaccggga gccgcacaca aatccaaaac tttttcaccg
     8701 ggttttgctg cagcagctgt tccaacgatc attgcacttg gttcttggct atattcatac
     8761 ccagcttgat ggaggaaaga ctttccattg acagtgccaa gaaatccctc attgctgtag
     8821 ggagcgggtt gtaattcttc gctatggtaa gtttggacca tgtccaatcc tgccggtttt
     8881 agtggattcc accgaaatcc ttttttcacg cttccttgtt caagcgcaga aaaaaaatcg
     8941 gatgcttctt cgcctaaaag aagacgatat tttttgataa attgctgtgg taacgttgtc
     9001 gcttcctcct tcattccaat gtttcgttag acattttaca atctttttta cgaaaaataa
     9061 aggtggctga tctacttttt catgttgctg cctaaggtga ctgttccttt aagatatttt
     9121 ccaagtattc atccgtcacc tcgtttttat cccaaacagc gttcatcatt tcaagaaaat
     9181 cttgagaaga atcatctgag cgcaaacttc ccaatgcatt aagccatacc aattcaagcg
     9241 acttttcttc tttgatcttc gtgtgacctt tgacatatga gaaaaatggc cgcttaaata
     9301 gcgaatccat gtctaaatca gattttgcaa tgatttcacg aatactttca tggatagaaa
     9361 aaaaatcttt caataagtag acaatgctta aaacatcatc ggaactgcat tcagctaagt
     9421 agttttcaaa ataaacagtg atttcttcta atatcttctc ttttaacccg ctgattgatt
     9481 tgaaatgtgt ataaatcggg tatgtagaac aaccgcagaa ctctgctaac tctcttgcag
     9541 taattgactt cattccatat tcttccacgt ataccatact tttgaacagc aaatattctt
     9601 tactataatt tgttactctc cccatcattc ttacctccgt ctcttttcat ctacccataa
     9661 ataaataaca taaataattc taaaaatatt attgataatt atcaaaacat atttagttat
     9721 atccattaaa aatcaatttt tccgccttaa aaacaagaat atcttgacaa aataccctag
     9781 gaaataaaca atagaataaa caaggtaaca aaaaaattaa ataacgttat ataaaaaaga
     9841 aggcgacact ctgtgagaat aacacagact gaaatgactt tccactcaca gtttttgtct
     9901 aactatatac aaaaacagaa taaaaaggag gtatttatgc taattgaagc aagaaaaaaa
     9961 gagttacttg ttctacaaat ggtcattcaa aaaaataatt gttctttaca agaattatcc
    10021 aatgacttac atattccaaa acggacaatc aaagaactga tccgaaaaat aaatgtatca
    10081 ctcaagcaat ttttattgat tgatgaattt atttattcta atcataaagg agagatccaa
    10141 accaaagaaa ccgatcaaac taaaaagtta gctgtttttt ctaagttaaa attatgctac
    10201 ctaaaagaat ccaatcgttt taactatttg atgttactaa tcaattatcc acaaactgct
    10261 gtaccaaaaa aatatttact tgaacaactt tatatatcgc cctcctatct cgaaaaactg
    10321 acaaaacagc tcaatcattc cttaaaaaaa ttccatttac ggatcctatc tgtaaaaaat
    10381 tgctgtactc ttgaaggaaa tgagttatct atccgtctct atctttactt ttttctttca
    10441 gatacatttg gaggtaacga ttggccattt tcctcacttg aattaaatgc actaaaaatg
    10501 aacagtacag atgagcaaat agaaaaaatt tcaaaacaag aaaaaaatat ctacttgctg
    10561 ttaactttat tcatattacg aaacaaacaa caggcatatt ttccaaaaac ttcttctgaa
    10621 atcactgaat tgatggactt attgcagcat acacatgatt attcagaata ctttacttct
    10681 ttttcagtga gtcgcccttg tgaagagaca gaaacagaga gagcctactt taattatttt
    10741 ttctattgtt tttttccaaa tcaaatctct tttcgacaaa aacaggagat tggtttttta
    10801 ttttccacaa gcaaaaacct tatttgtcga caagtcggtc aattgatgac ttacttaact
    10861 caacagtttc ctctcaacca tttagaaaat aaaataccaa tttattttta ttttcttgtg
    10921 ttggcagttg tttttttcga actgttgggt gaatccagca gtagtttttc tacactttgc
    10981 tttccagaag ccacgtccaa tcattctagt tcttttatac aggaaaagaa attaagagaa
    11041 aaaatcgata caattttttc aaaaaatggg gaaagaaacc aaatcagtca ataccttagt
    11101 caattgatcc aacacttact acaaacagaa acgaaagagc agttactcat ccatttgcag
    11161 ataaccaaac agtttacagg aaattatcat cttcaaagcc atttgcagca gttatttcgc
    11221 aaagatgctg ttaaaattac cgcatattca gaacatgctg atttgatcat tacagatcag
    11281 catgagaaaa tttcagatga aacggagact ttctatctgg atacaacgca caatacagtg
    11341 ttatttggca agttaataaa agcggttcat gaactgtata tgaaaaaagg ttatgagaac
    11401 aaaacaaaga ggatgtgaca aaattcttgt cacatcctct tattccaaat aaatggtatt
    11461 caatcagcta actctcggta ttagctcaga tcaaagcgct gatttcacaa cttctttatt
    11521 ttaatctctt cggttgccgc cgaacaataa gatcaagcgc aacagctgca ggaatgtcga
    11581 aagcgctgct gcaacataag tcagtgctgc tgcaaataat acgtgtcttg ccatcggtac
    11641 ttcttcttcc gtcagtagtc cgccttcact caaaatttgg attgctcgcc gagacgcgtt
    11701 aaattcgact ggtaatgtca ccaattggaa aagtaatgct aaagaaaaag cgaaaatccc
    11761 gatattgatt aacgtagagt tccagctaag caatacacct accataatca aggggaacga
    11821 aatcatcgaa ccaaagttag ctgctggaac aagtgctgca cgaatcttca atgggacata
    11881 acccgaagca tcttgtaccg catgtccgca ttcatgagct gctacaccta tcgcagcaac
    11941 tgaagtagac tgtgcagttg cttgagacaa actcaacatc ttattacctg aattgtagtt
    12001 atctgtgaga tctccggcaa tttgttgaac accgacatta tttatctgtt gactttgtaa
    12061 tatatattgt gctgcttgtg taccagtcac attgtttttg cttctcactt gatcgtattt
    12121 tcggaaagta ctattgacgt acgctgacgc aattccggaa ataactaatc caagaatgac
    12181 caaaagaaat gtcggatcta aaaaaccata cattccataa ccatacattt tcgtttcact
    12241 ccttttcgtt tactttattt tatcattagt agtaggaaaa gaatgtgaaa agaccttgaa
    12301 tattctttaa ttctttttca caaattccga tttcagtttc atcggtccaa atccttctac
    12361 cttgcaatcg atattatgat cgccttctac taaacggatg ttcttgactt ttgttccttg
    12421 tttaatggca cctgacgcac cttttacttt caagtcttta atcactgtca cgctatcgcc
    12481 ctctaacaga cggtttccat ttgcatctaa taccactaat ccgtcttcta tgacagtttc
    12541 ttgttcttct ttgttccatt cgttcccgca ttctgggcaa atcaacaagc ctcgatcttc
    12601 atatgtgtac tctgagccac attctgggca atttggtaat gtcatcttct ttctccttta
    12661 aaatctttag tgagcactat tgtaacggaa aaagaagatc ttgaaaagat acatttgtga
    12721 tttttactac aaaaggcacg ttttcgaacg aagtatcatt ctgtttttct gctcttatac
    12781 gattggcata tatcttggat ctctttatag atttcctcta cttctgctaa atcttttgca
    12841 ttcgcaccac ttgctaatgg atggcctcct ccatgatggc gtttagccaa ttcattgatg
    12901 atcggcccct tagaacgtaa acgtacgcgg taataccctg aaggctgctg aacaaaaatc
    12961 ccccaagcca gcacttcgtc aatcactcca ggaagtgaaa cgatcgaagc tgtctctgaa
    13021 tcatcgattc catatttatc aagaatttct tgcggaagga ttattcttcc tgcaccattt
    13081 tcatccacct ggatattttg ataaagataa ccggaaagtt tagcgacttt catcggcatt
    13141 tgttcaatct ctctgttcaa agcacttgca tcaaatggat aatttctcaa tatcgaagca
    13201 atctctaatg tacgggacgt cgtggaggga tacaaaaagc gccctgtatc tccgacgatt
    13261 cctgcataaa gtaaccgtgc agccttaacg ttcatcttta aagattcagg aaacatcaaa
    13321 gcaaattctg caatcatctc actacagcta cttgcttttg tatttaccca cacaagatct
    13381 ccataagggt catcattggg atgatggtcg attttgatca gtttttctgc caactgatat
    13441 ctttgatcac tgattctggg tgaattagct gtatcagtca cgatgactag cgctccttgg
    13501 tagaagacat cttcaacttc ttgcatttct gctaaaaagc gaagcccttc aatcgtttca
    13561 cctacttgac gtatttcttt ttctgggaaa ctttcccgta atagttcggc taatcctact
    13621 tgtgatccta atgcatcagg atcagggcgc aaatgcctgt ggataatgat tttatcgtat
    13681 ttttttattg tatctactat ttcttgctgt actgtcattt cactcctgct ttctaagaac
    13741 gttccattac ttgacaaaca acgattgctt tggaaacgat ggtgttttca ataaacactt
    13801 cgatatccag tttagcggaa cgtctgccga tttccaatac acgtggacga atgtctaatt
    13861 cgctttccaa ttggatcagc cgcaaataat gtaggttcac ttgttcaatc aagatatttc
    13921 gtttttggtt catcaccatt gttttttgtg cgacatcaga aatgatttcg ctaagtacgc
    13981 caaaagaaat ggttccaacg ccattgacca tttgtggtgc tactacgaat ttgaacttag
    14041 ggttttccaa acgatttcct tcacggtcag tatcaatcgt atggatattt ccagatatct
    14101 gatccgaaat cgtatctgca atctgcggtt gtcgctggac aagctgcatc gctttcatta
    14161 catcttgccg ggtaatcaag ccttccaatg tcaagtcatc ggaaacgacc ggcatgactt
    14221 ctagcccatc ccagatcatt tgatggctaa cagaggcaat actcattgtt ttctttacac
    14281 tgattggttc tttcgtcatc acccgatcga tgatctggtt tggcgatttc cctaaaacat
    14341 cttttgccgt aacaatcccc atcaaacgat gatggcggtt gacgactgga aaacgcgaat
    14401 gctgcgtttc ttctgacaaa cgctgataat cagaaatcgt atctgtctgc tgcaaataat
    14461 gagtcttttc agctggcata tagatatcac tgacaagcat gatatctttt ttgatcaatt
    14521 ggtcgcttaa cgctcggttg atcatggttg cgactgtaaa tgtatcataa gaggtgcgta
    14581 agatcggcat ttcaagatca tcagctagct ttgcaatctc agcagtcgta ttgaatcctc
    14641 ctgtgatcaa tactgcggcg ccatcttcca atgctaattt ttggacttcc gcccggttgc
    14701 cgacgatcat tagtgatcct ggcgtaatat agcgttccat ggcatgttta gtcatcgcgc
    14761 cgatgacgaa tttattcaag accttgtcta atcctgccgc cccgcctaaa acgtcccctt
    14821 caatgatcct gacgacctcg ccaaatgtca aacgttcaat atgttttttt aatttgcgtt
    14881 cgatacggat ggtccctact cgttgaattg ttgaaactag tccgacattt tctgcatctt
    14941 tgattgcacg gtacgctgtt ccttcactga cattcaattc ttttgcgatg cttcttacag
    15001 aaattcgatt gccaacaggt aaactttcaa tatattctaa aatcaaatca tgttttgtcg
    15061 ccattttctg cctacacttc cagcgtttcc gagacgctca ttatttttcc ttcactatct
    15121 tccagtaact ctacaaaaga ttcgggatct tgttcaatga cagggaaagt attgtaatgg
    15181 attggaacta ctttcttggc acgaattgtt tgcgcagcct ttgctgcatc ttctggcccc
    15241 atcgtatagt tatcgccaat cggcaagaaa gcgacatcaa tatcgaattc ttctgcaagc
    15301 aatcctagat cactgaaata agcagtatcc cctgcatgat aaatcgtttt tccttctgct
    15361 tgaataataa ttccgctagg ctcgcccata tactgaacga taccgtctac ttcatagctt
    15421 gaactatgct gtgcatgtac gaattttacc acgccgaatg gaaacgcatg ttttccaccg
    15481 atattcatac cgaatgaatc tactcctctg ctgttcgcat aatcagcaat ctcaacaata
    15541 ctgataattg tggcttgatt ttcttttgca ataggaatca tatctcctat gtggtcacta
    15601 tgaccatgag taatcagcaa ccaatctgtc tttacttctt ctgcagttaa gtctgtcaat
    15661 ggatttcctg taataaacgg gtcaatcatc acgcgttggc cattttccat ttcaattgtt
    15721 aaacaggaat gtccatgata cgtaattttc atattttaca cctcgcgttt tctctgtatc
    15781 ttttttatta aaaacgattt catcacttgc acatcaatga aaaaatatag ctgctaaata
    15841 tattttcatt ggattgatag tacagtatgt acaaagcaat tgtaacagat aatacaggat
    15901 gcaccaagta ccaagcagat ataatctcaa gtttgaggtc tctgctctgc ttagcttctc
    15961 ttctcgtccc ttaactaatt aaatcagcgt aaataggatg gacgatcttt tctaaatcgg
    16021 ctacttttat ccgaaggctt ctcccgattt caccgcttga cacaattact tcttcttttt
    16081 cttttaaaga actgtctgct aaaaaacaat aatcaggatg tgcgagtttt attccaatag
    16141 gggtgtttgc tccgtgggga tatcctgtat gcattaatac aaaatccatt ccaggaaaac
    16201 caactttacg atctttcgtc acttgtctcg tttttttgta atctaagtga tcgttcaaag
    16261 gaatcaatgc gatgatcacc ccagttttgt ttcctttcac tacgagagtt ttacatatca
    16321 aagctggatc aatccctctt ttttgtagtt cttctgtgaa agattcttct accacatgac
    16381 taaaatcaag tggttgatag ctgatctttt gttcttctaa ataacgttcg acttttgttt
    16441 gactcatcat tgattcactc cctttattct atcgtttatt ataaagcgag ggatgctgta
    16501 ttcaaaa
//
LOCUS       DAFBSV010000064        15943 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.065, whole genome shotgun sequence.
ACCESSION   DAFBSV010000064 DAFBSV010000000
VERSION     DAFBSV010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.065"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(139..1125)
                     /locus_tag="LLB18_001963"
     CDS             complement(139..1125)
                     /locus_tag="LLB18_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBK5244959.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1148..1714)
                     /locus_tag="LLB18_001964"
     CDS             complement(1148..1714)
                     /locus_tag="LLB18_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBK5244960.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(1728..2144)
                     /locus_tag="LLB18_001965"
     CDS             complement(1728..2144)
                     /locus_tag="LLB18_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBK5244961.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(2601..4535)
                     /locus_tag="LLB18_001966"
     CDS             complement(2601..4535)
                     /locus_tag="LLB18_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBK5244962.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            4816..5772
                     /locus_tag="LLB18_001967"
     CDS             4816..5772
                     /locus_tag="LLB18_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBK5244963.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            5862..6965
                     /locus_tag="LLB18_001968"
     CDS             5862..6965
                     /locus_tag="LLB18_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBK5244964.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            6978..7931
                     /gene="menA"
                     /locus_tag="LLB18_001969"
     CDS             6978..7931
                     /gene="menA"
                     /locus_tag="LLB18_001969"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HBK5244965.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(8745..10091)
                     /gene="gor"
                     /locus_tag="LLB18_001970"
     CDS             complement(8745..10091)
                     /gene="gor"
                     /locus_tag="LLB18_001970"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HBK5244966.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10225..11478)
                     /locus_tag="LLB18_001971"
     CDS             complement(10225..11478)
                     /locus_tag="LLB18_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBK5244967.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(11484..12407)
                     /locus_tag="LLB18_001972"
     CDS             complement(11484..12407)
                     /locus_tag="LLB18_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBK5244968.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(12628..15120)
                     /locus_tag="LLB18_001973"
     CDS             complement(12628..15120)
                     /locus_tag="LLB18_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBK5244969.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15127..15594)
                     /locus_tag="LLB18_001974"
     CDS             complement(15127..15594)
                     /locus_tag="LLB18_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBK5244970.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(15730..15803)
                     /locus_tag="LLB18_001975"
     tRNA            complement(15730..15803)
                     /locus_tag="LLB18_001975"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(15767..15769),aa:Arg,seq:acg)
     gene            complement(15861..15934)
                     /locus_tag="LLB18_001976"
     tRNA            complement(15861..15934)
                     /locus_tag="LLB18_001976"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(15898..15900),aa:Pro,seq:tgg)
BASE COUNT         4658 a         3333 c         2841 g         5111 t
ORIGIN      
        1 aaaaagagca acgtcgctaa cggacgttgc tctttatttt tgctttttat cataaataca
       61 agaactacaa ttcaatttgt caaaaaacac gtagatttcc ttctgagaaa tttatttacg
      121 tatcgaacct ttccctattc agtctttgcg atccaaaatc agttgggtaa gggaaaagag
      181 attctctttt gttcgaagag aggtggcagg taatttcttt atttccttca aagccttttc
      241 tgtgtaagag gccgctaact tcctagcttc ttccacgcct cctgtatgtt caacgatttt
      301 gcgtacggcg tcgacatctt cttctgtcat tgccgctttc ttctctaaat aaggtagtag
      361 ctttggtttg tttttttgca aagagtagat caacggtaaa gaatagaccc cttgacgcat
      421 gtcttctagt acaggtttgc cgatttcctg gctctctttt gtataatcta aaatatcatc
      481 gataatctga aaggccatcc cgatagaaag tccgatatct cctgcttttt ttgcgaagcg
      541 ctcgcttgtt ccactttcaa aagcgccaac agaacaactt aattggaaca gttcagctgt
      601 cttacctgaa atattttcca aatattcttt tacagaaagt tcataattat agcgatcatc
      661 catctgccct aattcgccat tcaatacttt ttccatactg cgagaattca attggagact
      721 tttcaaggaa gtggagtaat cagacaatag tttaaaacag cagacaaata aatagtctcc
      781 tgcatagaca gaaacgacat taccaaactg actacggata ttaggctgac cacgtcgcag
      841 atccgcttca tcaacgatat catcatggat cagtgtggcc gtatggagca tttcgataga
      901 agctgccaaa gcgatggctt tgtctcgatc ttgctctggt ccaaattgtg agaacaatag
      961 ctgataggca ggacgcaaca gctttccgcc ggcatggatc gtttctttga tggcttgttc
     1021 gacaggtttg tttttcaggc ggacagtttc ttccatccgt tttagtgttt ctgtcaattc
     1081 tttacttaaa gcaggatagt tttcccacat tggatgtagc ttcataaaaa aactccttgt
     1141 gtgacgatta ttttttggta aacattgggc tccatttttg tttggttccc tgctcataat
     1201 ctttttggaa tcgttgaagt gtctgcacat gtcgtaaaag ataattcgct gcgatcccga
     1261 ttgcaatccc tgataaaatc cctaaaactg aaaggactgg caagtacaac atgactgtcc
     1321 atgattgtgc aatgaaagaa gccatcaaaa gctgtccgac attatgcatg aaaccgccgg
     1381 ccgcactaat tccgatgata ctgacacgtt ttggtcctaa ttgcttgacc aataacattc
     1441 caaaataact aagcaaagca ccactcatac tataaaggaa tgtggaaatc gttccgccta
     1501 gcaaagtagt caggaatagt cgtagccaaa gtagtaagaa gctgtcttgt tttttcatgg
     1561 taaaaatggc aacgatcgtg attagattgg ctaagcctag ttttgcacca ggcgcaaaag
     1621 aaaaaggata agggatcata ttttccaata aaccaatgat cactccttgt gcaacaagta
     1681 gcgaaatata aatcattttt tgtaatttac tcatggtgtg tgaaggtcta ataaatcaga
     1741 ctgtcttcgt cacctccatc tgttgaacgg acttcgatca ctaatttatg tggcaaacag
     1801 acgatggttt cgccattttt cgttgcccag cctcgacgta cgcagatctg gtcatcgcaa
     1861 tctgcttctt ttatccgtac tcgatcgcca tctatctcga tcaagttata atctccgtgt
     1921 tcatctttgt aagtatatgt gttgctctct tctccagcca tcaaagggaa tgttttgatt
     1981 tctgtgccat ccacacgcag taccgcttct ttttctgctg ttgcggtgtt ttgctgaaga
     2041 ccaaaaatca tgactggtaa aaaagaaaga acagtcaaaa gcaaaataat aaaaacatcc
     2101 caaggtttga gcagactttt ttcagcaaat tctttaaggc tcatttttgt tctccttttt
     2161 ccagattaac tcacccaatt ttagcataaa aacaagaggt tgtgacacct gtgtcttgct
     2221 ttgagtaata agaacgaaga atagaaaaca gctttccatg ttttctaatt ctttgggctt
     2281 attaccgaga agcagcaggt ggaacaccgt ttataacaag aggttgtgac agaagtgggc
     2341 aacttcaaga aataagaagg aatttacgaa aattactttt caagtttttg tgaaatttcg
     2401 gcttattttt cgaagaagct acttctggaa caccgtttat aacaagaggt tgtaacagag
     2461 gttgtgacac ctgtgtcttg ctcatggagg cttatctcgg gcatcttatt cctttaattt
     2521 tacataaaaa ggaggctgtg acggtttgtc tcagcccctt tctattgaaa tcttgcattc
     2581 aaataacgtt ctttatctat ttatttcttg ccgtactggg aacttggtct accgtaccac
     2641 caattaccta gtgtacgttg tagccatgga attacccagc gatccaaccc aatcgcacgt
     2701 ccggaaccgt tcatcaatgc gaaagcaaca aaaatgaacc aaatgtttac ccagtaaaac
     2761 atgcctgata agcagaacgt gatcaccaat acaatcgttg tcgcactgca tagccatgtg
     2821 aataatccag caatcaatgc taatgccaag gcaatttcaa agaataccat gaatttttgg
     2881 aagaacattg ctacatcatt gtttggcatg atcacttgca tgatctttgt gaaccagtct
     2941 ggtgacttct caatcacagc cattggttct tcaccgtatg cataactcaa accaaaatgt
     3001 gcagcttgag tcgctgcttc tccggcactt gcccctgctc cgctggcagc tgtggttgca
     3061 tcaccagcag cagaagcacc actggcaaca tctgttacat tgtattccca tgtccaaggg
     3121 aacacactgt ttccagtgaa ccatgatcct tcaccaaacc aagtacttgg tttgaacact
     3181 tcaccattcc caatgatttt tttggaagct tcaacgaacc aaactaaacc atagaaaata
     3241 cgaagtggca cactccataa gacattgccg taacgagaag aatgtcctcg agtcacgttg
     3301 cgatcatctt tgatatggaa aaactcatgc attaaatatt ggaacatata ataaccagaa
     3361 cgaatatcaa agaagtattt caaattcacg atatgtttca ttacgatagc taaaaatccg
     3421 cttaaatgga tcttatcaaa taggttagct accccccatt tggcaccaat agaaaccata
     3481 aatccttgat agtttccttt aaatttatgc ttttctccgc ctttgatcga agccacgata
     3541 ttcgctgcgg ctgtgtgtcc tgtttgttca gcagcttgaa cgatctgcgg tgtcggtgtt
     3601 cctgggaatt cttcataaaa gactaaatca ccaatgatat agatgttttt atcttcgtag
     3661 ccttttgcct gcatatattc attggcgatc aaccgctgtc cgcgtgctga ttctaatcca
     3721 aagtcagcag cgtcagaagt tcctttgaca ccagctgtcc aaatcagtgt gtgagtcgga
     3781 atgttgcgtc cgtctttcaa tttgatatga tcagcagcca cttctacgat tggtgcattc
     3841 aataataatt ccacgttgtg cttacgcaaa tagcgttcag cttttgcagc atcatttcga
     3901 tccaacatat tcaagatcgt cggcattgcc tctacgacca tcagtgtgat ttcgtttgga
     3961 tctaatttat aatctttggc taggcgattt ttccagtcga tcagttcccc aatcatttca
     4021 ataccggtaa atccagaacc acagacaacg aaagtcagca tggctttacg cagttcatca
     4081 tctggttcca atgcagcttt tgctactgtc ttctcaatat gttcccgaat ccttacagaa
     4141 tcttcaaatg accaaagggt gaatccgtgt gctttgacac caggtgtacc aaagtcattc
     4201 ggctctccgc ccattccaag gatcagctga tcaaaaggat aggaacctaa tttggtcttg
     4261 acgatttttc gttctttatc gataccgatt acagtgtctg tgacaagttg tacattcttt
     4321 tgacgagcaa acaaatgctg cagatcgtat tggattgctt ctggttctac acgtccgcca
     4381 gctacttcat gcaactcggt catcatagta tggtacgaat gacgatcgat cagagtaatt
     4441 gctacatctt cttttttcag tttctttgcc aagtattttg tagctgaaac accggcatat
     4501 cctgctccta caacgacaat attttgcttt gccattgatc atccgctcct tatagactat
     4561 ctatataatg aatatatgat aattctttta gtttgatact tattacacaa tctccatata
     4621 ttatatagat gttctgttct tttgtctaac tccttttgga tttttttcaa attttaaaat
     4681 aaagcgtttt ttcacgaaat ttgctgaaag aaaacgtttg aaatattaca tgggttattt
     4741 atcaaaaata gttgacttat aggctaaaaa gattagaatg tataatgaat cacaaagaaa
     4801 aattgtggac tagaaatgga atggtggggt attaaaatga agaaaaaacg ttttgtaact
     4861 ggatttgccg tattagcatt ttcagctcta gtgttaggcg cttgcggcgc agatgacaac
     4921 ggaagctcaa actcttcttc tgaatcatct acagcacaat cttcgactgc aaaaagcaca
     4981 acagaatcat ctgcaaaagt tgtagctggc ggagatttgc aagacggcac atataaatta
     5041 gaagaaaaaa attattcaaa tggttaccgt gcagtctttg aaatggttgt aaaagacggc
     5101 aaaatcactg aatcaaaata tgataacgtc aatgaaaacg gcgaatcaaa aacaaaagat
     5161 gcagaataca acaaaaacat ggaagcaaaa tctggcacaa acccagaaaa atacattcct
     5221 gagttgaatg accaattctt aaaagcacaa agcgcaagcg gtgtggaagt cgtaactgga
     5281 gctactcact catctgaaag cttccaaaac tacgcacaac aattgatcca agctgctcaa
     5341 gctggtaaca cagatacaat cgaaatcgac aatggtgctg atttgaaaga cggcacttac
     5401 aagcttgaag aaaagaacta ctctaacggc taccgtgtgc aattcgaaat gacagttgct
     5461 ggcggcaaag taactgaatc aaactttgat tatatcgaca aagacggtaa atcaaaacaa
     5521 gatgatacag aatataatga aaatatgaaa gcaaaaagcg gtacagaacc aaaaacttac
     5581 atccctactc tgaacgacga attcgtcaaa gcaatgggcg aagaagatgg ctcacctgct
     5641 aatgtagaag ttgttacagg tgctacacac agctcacatt cattcatcat gtacgcacaa
     5701 caattagtga atgcagctga aaaaggcgac actcaaacaa tcgaagtaga taatatcgta
     5761 acagaaaaat aatcacataa tcatactaat aaaagttgga gggtgggacg atagccagat
     5821 taggcagtcg tctcaccttt caaaatgaag agaggaaaaa gatgcggaaa aaactactat
     5881 tttccttaat cacactgggc atctctttta tggtgctaac tggctgcagc aactcagcaa
     5941 ataaaacaac cactgaaagt tcagcagcta ccaagatatt gaaagatcca tattctgatg
     6001 aacagttctt gttagggact tacgttcgta tccgtgtgta tgatgaaggc aaagaatcag
     6061 cattgaaacc tgccttcgat cgagtaaaag aacttggtga taaaatcacg atcaatcaaa
     6121 aaggttctga gatcgatgaa gtgaatgagc aagctgggat caaaccagta aaagtttctg
     6181 atgacgtcta cacgttagtc aagcgggcct acgaatatag ccaagattct caaggcggat
     6241 tcgatatggc gattggtgca atcacacaat tatggcgaat cggttttgat gacgccagaa
     6301 aaccttccca agaagaaatc gatcaggcat tgaaattagt ggattatcat aagatcgaac
     6361 taaatgacaa agaaaaaact gtttatctaa aagaaaaagg aatgatcatc gatttaggtg
     6421 caatcgccaa aggttacatt acggacgaag tagtgaaagt cttgaaaaaa caaggagtga
     6481 ccactgccat cgttgacttg ggcggtaatg tctatgtctt aggccacagc ccaagaggcg
     6541 aaaaccaaga ctggacagtc ggcatccaag atccgaacat ggctcgcgga tctgttttag
     6601 gttctattaa agaacggaac aaaacattag ttacctctgg aatttacgag cgttatttag
     6661 aagtagatgg caaaaaatac catcatttgt ttgatccaaa aacgggttat ccgttcgaca
     6721 atgatatcgc aagtgtcacg atcataacag ataaatcaat tgatggtgac gggttgtcta
     6781 cagcagtctt ttcaatgggt gtgaaaaaag gactggaata cgtcgaaagc gaattgaata
     6841 acgggacgga agcgatcttc gtgacaaaag acgataaagt atatgtgacc gatccaatca
     6901 aagacacctt caaattatcg gaggactccc attacacgat gggtgaccgt tctgaactaa
     6961 aataaggagt acgaaccatg acactaaaaa tctttttaga agtagttgaa atacgaacaa
     7021 aggtggctag tgtatttcct tttgcggtag gggtattatt ctctatcgct ttttttcatg
     7081 agatacattg gctaaacact tttttatttt ttattggaat gctagttttt gatttagcga
     7141 ctaccgctat caataattac atggattatg aaaaggctca ttctgaagta tataagtatg
     7201 aagaaaatgt cattggccgc agaaatctat ctcctgtatt gattcgaaac atgattttag
     7261 ctatgattgc atttgttttt gttatcggcg ttattctaac gatcaatacg ggttggcttt
     7321 tacttttgat gggatttatc tgttgtttta ttggagtatt ctatacattc ggaccgattc
     7381 ctttatctcg aatgccttta ggggaaattt tcagtggggt gactatgggc cttggaattt
     7441 ttgccatggt cgtttatgtc aatacattcg gttcagatgt ctatgatctg acagtcaact
     7501 tttcatctgg acaatttgat ttggtaggaa atctttgggc tatagcagca atcgtattag
     7561 cttccttacc cttggtgttt acgattgcca atatcatgtt ggctaataat ttgcgggatc
     7621 ttgaccgtga tattgaaaat catcgctata cactagtttt ttatatcgga cgtcctgcgg
     7681 gaacagtctt attccagcta ttgatgtatg cttgctattt cgtgatttta atggggttgt
     7741 tgagcggtat ctatgaatgg ccgatcttgg tcaccttctt gaccttgcca attgtgaaga
     7801 agcatttgga tcaattcaag caaacgttac cccagcctat cagtttcagc tattccatca
     7861 aaaatatggt cttattcaat gccagttatg tattggggct attactaaca atcattatgc
     7921 aagccattta acagcatgaa gaggttgtga aaaaactgcc ctgcatcaag taataagaac
     7981 agccaaataa aaatagctcc ttatattttt cgtttggttg ggcttattac cgcagatgca
     8041 agcttttgaa caccgtttat caggaggttg tgaaaaagtc gcttagtttc gagtattaag
     8101 aaaaattttg tgaaaatggc tttccacatt tttgcataaa tttggcttaa taccgagaaa
     8161 ctggcttttg aacaccgttt atcagaggtt gtaaaatcag tgttttgtcc tgagtattag
     8221 agaaacaaat ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgaagga
     8281 cagctgattg aacactattt gttcggaaaa agtgactaac tatgacacaa tttttttcac
     8341 agtccctttt ttcacttgat ttgattcgta ccagcgaact tgacgagaac tttcttggtt
     8401 tggtaactat atggtattct tttaacatcc tcgtttgctt cttctaattt atttatacaa
     8461 agtcacactt ttttaaacat ctgttcttcg atacatttct atttctttta aacatcgata
     8521 ccaatatttt gaacttaaga gtgcatacca aatggattca tttactcttc gtcagttacg
     8581 aagataatca aaatctccaa cttccctact tatttcgttt tgagaattat cgaagcaatc
     8641 ttacataaat aactaaaaaa caaaaaacca gaaaatcagt atactgattt tctggtttta
     8701 catggtttgt tcaataaaaa gctgttggaa ctgttaatat taaattatcg catcgttacg
     8761 aattcttccg ctcctgttgg atggatggct actgtattgt caaagtcttc tttagttgca
     8821 cccatcttga tagccacggc aaaaccttgc agcatctcat cgacaccaac accaatagca
     8881 tgtaagccga cgattctttc ttcttttccg acacagatca atttcatttc gcatttttgg
     8941 cgataatcat ttaatgcaaa gtacattggg gtaaagcgtg aacgataaac tttcaattca
     9001 ttttcgccat atttttccaa tgcttcttct tctgtcaaac caattgttgc aattggtgga
     9061 tgcgtaaaga cgactgtcgg aacaagttta tagtcaagat aagaatcttt ctttccatta
     9121 aataaacgtt ctgataaacg tctaccagct gcgattgcaa caggagtcag atctaattta
     9181 ccgatcacat caccaacagc aaaaatatgt tcatccgttg tattttggta tttatctact
     9241 ttgataaacc cttttttgtc caattccaca tttgtatttt ccagacctaa tttttcggta
     9301 ttcggtacac gtccaccggc aaaaagtaca caatcaccag ttaaggtttc accattttca
     9361 aatagcaccg tatattcgtc attgttttta gtaatttctt tagcaatatg atgtgcgtaa
     9421 gtttttattc cagcttcttg gtacatttgg atcaaattgt ccgaaagcat tttatcaaac
     9481 gttctaagtg gtcgttcttt tcgatatgcc cacatgactt cactacctaa accacgaaat
     9541 acacctgaaa gttcagccgc aatgtatcca gcacctaaaa cgattgctct cttaggtaac
     9601 tctgttaatt caaaaaatcc atttgaatca attgcgtatt ctccaccagg aatggtcatt
     9661 ttacttgcac ggcctccagt agcgatcaag attttaggag cacgataggt ttcaccgttt
     9721 acttcgatcg tttgactatc gataaaagta gcgtaacctt ttatagcctc gacatgattg
     9781 ctatctaatc ctctttgata agcaccgtgt agaaaatcaa tatatttttc tcgtctttct
     9841 actagaccgg cgaaatcaac attttttaaa tctgcttgga taccgtaact tgaggcatct
     9901 cgttcaattg tttccaaaat cgtacttgct tgccacataa cttttttagg tacacaaccg
     9961 acgttgacac atgttccgcc caattcattc gcttcaatca gcaaaacttt tgcgccatgc
    10021 atccctgctc tgtttgctga agcaataccg ccagagccgc caccaattac gatgtaatca
    10081 tatatttgca ttttgttcct ccttattgaa gagatcaatc aaaaccttta tttaacgatc
    10141 ctttttctac agaaaacaag tgtaacactt ttcttgaatt ttgtatgcga agatgcttaa
    10201 aacagggata tatcagcttt ttccttattt acgttttcgg atcatatctc caggtttcac
    10261 cggctgtgcg actggcatag ttaaaatcat cattggattt ggtgctcggt caatggattc
    10321 gccttcttca ttatgcataa cttcaacggt ttgactgaaa tgactgaatc ctggaccata
    10381 aaattcgatt tcatctccta cagaaaacaa gtttctctga cgtatcgtag caatctgtgt
    10441 tgcctcatca taagataata cttcaccgac aaatttatat actgggattt tacgacgttc
    10501 accgaataat tgttcgtttt cagttggtgt attgtagtaa aaacctgtag ctaattctcg
    10561 ttgtgctact ttccataact cgtcgatcca ttcttgcttg cagacatagt tttcaggatc
    10621 ttccatataa ctgtctacag ccgctttata gacatttgac accgtagata cataatggat
    10681 cgatttcatt cttccttcga tcttgaagct gtctacgccg ttttcaatca attctggaat
    10741 atgttcgatc attgacatat ccactgcact catcgagaat tcttcttcca cttcgcctgt
    10801 atcagttaaa ctgtttcgtt cttgaccaaa aggcatatcg aacaatccat acttccagcg
    10861 acaagattga gaacatccgc cacggtttgc atcccgcatc gacatatggt tggacaatgt
    10921 gcatcgacca gaataagaga tacacatggc accatggata aatgcttcga tttcggtatc
    10981 cgtattttta cgaatctctg ccacttcctc cattgaaact tcacgagcta aaacgacacg
    11041 ttccaaccct tcttctttcc agaattccaa tgtctcaaaa ttagttgctg aagcttgagt
    11101 ggataaatgg atcggcagac ctggggcttc tgtcgcacaa atttcgatca aagctggatc
    11161 agaaacaatc actgcagaaa taccgacatc acgcaaactg cggaaaaatt cccctgctcc
    11221 atcttcattt ccttcatggg tgaccatatt agcagcaacg tataccttcg catcatgttc
    11281 ttttgcaaaa gcaactcctt cagccatttc ttcataagta aaattacctg cacggcttct
    11341 taaaccatat gcattcccgc caatatatac tgcatctgct ccataatgga tcgcggtttt
    11401 taacttttcc agtgttcctg ctggcgctag gatttctggt cgtttcaatt ttctttttac
    11461 tgtcatttct ttcatcatac tccttatttg atagcagaag gatcaatata aaagaatcct
    11521 gtatctaatt cacggttttc aggatgcaat ttactgattt cgctagtcat tttttccgct
    11581 ttttcttgat cccagctacc ttctaaaatt tgtttttttg cttcggcgaa tagtcgagtg
    11641 atgtttacga atttttcgcc tggagtaaat aatccgtcca atttccatgt acagtaatga
    11701 tgctgataaa gttcattcaa ttcattcgag agattcagat cattgctggc aaaaatatgt
    11761 gtgccatgac tatcttcata aatagaataa tgtgtctctt cttttttagg ttccgagata
    11821 aaaagacctc tttcacgatc tttttgttcg tcttgtttcg tatagttata gtaattctgt
    11881 agcagtggac gtttggattg atggatgcat gtagcaccat acacaagggt ttctacagga
    11941 atatcgagtt tttcttccat cgccttcatc tcttcaaaag gaacttcacg agcaagtact
    12001 gctccaactg cgcctttttt cgcccagaaa ttgatttgac gtgcgctcgt tactaatgtt
    12061 tcagcatcat aaatatacgg tatacgcaat tcaggatttt ttttcatcgt ataaataata
    12121 cctgtatcac caactgtgat cacatctacg tttatttctt ttaaaaaagc caaatattca
    12181 ggtacatttt tcattttttc aggatgaatg atcccattta cagcaatatt cgctttttta
    12241 ccatacttgt gtgctaattc taccaattgt cgctgttctt ctcgtgtaaa tgaagcaggc
    12301 agacgcaatc caaattgctc ttcaccgaaa tatagtgtat ctgcacctgc agcaagcaac
    12361 tgttctgctt gttcaatagt ttctactgtg gttatgagtt cgatcataat tttctcctcc
    12421 tacaacttca taatagtagc atagctctaa aaactttcca atacttcttc tatttaaagt
    12481 cggatttttg aaaattattt cacaaaaaat caaaataaag ttcgatatat tctgtccaaa
    12541 tataaaaaga gattgtgaca aaaatcttgt cacaacctct taatcaagtc ttactattat
    12601 aaaaattcag ctacacaggc caagtaacta tagggaacct actgtttcct ttttaggtcc
    12661 gcgaacattc aatgtgatct taccttttga agcacctact gttacgtggt cacctaaacg
    12721 aatttctccg ccaagcaaag cctcgctcaa tcgatcttca atttcttttt gaagtgcgcg
    12781 acggattgga cgtgcaccat attcaggatc aaatccagct ttcccgatca catcgattgc
    12841 agatggtgtg attttcactt gaatatcttg ttctttcaat cgtttgataa tcgctttgct
    12901 catgatttgg acgattgtat ggatttcatc tttactcaat gaatggaaga cgacagtctc
    12961 atcgattcga ttcaagaatt caggtcggaa agctttcttt aactcttcta agatacgttt
    13021 ttgcatggct ttgtgatctt tagtaacatc ttggacattg aatccgacat ttttttcttc
    13081 tcgaatttgt gtcgctccga tatttgaagt cataatcatg attgtatttc taaagtccac
    13141 ttttctacct ttagaatctg ttaaatgacc atcatccaat acttgcagaa gtaaattgaa
    13201 aacgtctgga tgtgctttct ccacttcatc taagagaatc actgaatatg gtttttgacg
    13261 aattttttct gtcaactgtc caccttcatc ataccctacg tatcctggag gagacccgat
    13321 taatcggctt gtactgtatt tttccataaa ttctgacata tcaacacgga tcagggcatc
    13381 ttcacttcca aacatgactt ctgaaagtgc tttggccaat tctgtttttc cgacaccagt
    13441 tggtccaagg aacatgaatg aaccaattgg acgatcagga tctttcaatc cgcttcgtgc
    13501 acggcggatc gcacgtgaaa ctgctttgac agcctcatct tgaccaacga cacgttcatg
    13561 cagaagtcct tccagttcta acaagcgttc gctttctttt ttctccaact gctgtagagg
    13621 gacaccagtc cactccgata caactgtagc aacatcttct tctgttacac gatcagaata
    13681 accttgctcc tgttttgctt caattgcaga aactttttgc agctttttac gtagtgcttt
    13741 ttcttgtctg cgtaattgag cagcattttc aaagtcttgt ttttggatcg ctgcttcctt
    13801 ttcttgtact agttcatcga tttctagttt gatcacagtt gattttgtta agtgatcggt
    13861 ttgatccaaa cggactttcg ctgctgattc atcgatcaaa tcaattgctt tatcgggtag
    13921 ttgacgagaa gtgatataac gaacagaaag attgactgct gctcgtacag cttcatctgt
    13981 gatctccact ccatggtgct cttcatatct tgtacgtaat ccttgaagaa tcacttctgc
    14041 ttcttcagga gttggctcat ctacttgaat gcgagcaaaa cgtcgctcta atgcagaatc
    14101 tttttcgata tatttttgat attcatctag ggtcgttgct ccgatcgttt gtaattctcc
    14161 tcgagctaac gccggtttca agatattcga agcatcaatt gctccttctg ctccacctgc
    14221 accaattaag gtatgcaatt catcaatgaa taagattact tgaccatcat tatagatttc
    14281 gtcgatgacc tttttcattc gatcttcaaa ttcaccgcga tatttcgtac cagcaaccaa
    14341 agatcccata tcaagcatca tcaggcgctt ttcttgcatg tcttctggca cttcacctaa
    14401 aatgattttt tgagctaacc cttcagcaat ggctgttttg cctacaccag gttcacccac
    14461 cagtacaggg ttattctttg tccgtcggct aagaatctgg ataagccgtt tcacttctct
    14521 cgaacgacca acaactgggt ccagcttgtt ttcttttgct aatttcgtca aatcacgtgc
    14581 taatgaatct agcgtaggtg ttccttgcgg tgtttgccgt ttatcttgta catttacatt
    14641 tctacgacga ttcattcctt ttccagcaga atcaccagct agccccattt tttgtttcag
    14701 aacttgacgg gcttttgaaa ggctgatacc taagttgatc atgattcgag tagccatgat
    14761 actttcatct tttaataagc tcatcaaaat atgttctgtt ccaacttttt gagaaccagt
    14821 tttcttcact tcgctgctag ctaaagcaaa aacttgtttc attcttggtg aatatggaag
    14881 aaagactcct ttagggtaag aacggatacc accataacca atcagatgtt caatttcttc
    14941 ataaatttcc gtttcattca aatccatttc acgtaatact tttccagcaa ttccattttg
    15001 ctcgaccact aaggctagta aaacatgttc tgaactaact gattgatgtt tcaaccgttt
    15061 tgcttcttct tgtgcaattt ctaatactgc ttgggctctt tcagtaaaaa gttcttccat
    15121 ctaatctcac ttcccatctt cataacttaa acgttccaga aatgctcgga gaatccgagc
    15181 acgtgtatga tcttcatatt cattgaaatt caatgtgttt tttgcaattg cactcaacat
    15241 caagtttcct tctttttttg taattatttg gtcttcataa agtttttgaa taatagcaaa
    15301 agcatttttc tcactgattg tatcatcaaa taactgattt atctgctcaa gtaattgttt
    15361 tttatctgaa atccttactt ttgcaattcg tatataacca ccaccaccac gtttgctttc
    15421 tactagataa ccacgttgga tggtaaaacg ggtattaatc acatagttga tttgtgaagg
    15481 aacacagtta aagaggtctg ccatttcaat ccttcgaatc tcgatcattt cactattttc
    15541 cagaattttc tttatatatg attcaattaa atccgaggta ttctgatgtg ccatcttatt
    15601 cattcccttt gactaatatt gaccttaatt ataacgaatt tgataataga aagaaagaag
    15661 aacgcttttt gttaaataaa tcctttagaa tcaacaaaaa aaaatacgga atatactatt
    15721 ccgtatcgac gcgcccaaga ggagtcgaac ccctaacctt ttgatccgta gtcaaacact
    15781 ctatccagtt gagctatggg cgcatattca atttaaaaaa attataaatc atttgaaaac
    15841 aaaaagcaag ataaaaaaaa tcgggaagac aggattcgaa cctgcgaccc cttggtccca
    15901 aaccaagtgc tctaccaagc tgagctactt cccgtttaaa aaa
//
LOCUS       DAFBSV010000065        15938 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.066, whole genome shotgun sequence.
ACCESSION   DAFBSV010000065 DAFBSV010000000
VERSION     DAFBSV010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15938
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.066"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(173..475)
                     /locus_tag="LLB18_001977"
     CDS             complement(173..475)
                     /locus_tag="LLB18_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244971.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(695..1061)
                     /gene="ssrA"
                     /locus_tag="LLB18_001978"
     tmRNA           complement(695..1061)
                     /gene="ssrA"
                     /locus_tag="LLB18_001978"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1232..2005)
                     /locus_tag="LLB18_001979"
     CDS             complement(1232..2005)
                     /locus_tag="LLB18_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBK5244972.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2149..2499
                     /locus_tag="LLB18_001980"
     CDS             2149..2499
                     /locus_tag="LLB18_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBK5244973.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2480..3196
                     /locus_tag="LLB18_001981"
     CDS             2480..3196
                     /locus_tag="LLB18_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5244974.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3196..4644
                     /locus_tag="LLB18_001982"
     CDS             3196..4644
                     /locus_tag="LLB18_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK5244975.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4714..5223)
                     /locus_tag="LLB18_001983"
     CDS             complement(4714..5223)
                     /locus_tag="LLB18_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244976.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(5213..5938)
                     /locus_tag="LLB18_001984"
     CDS             complement(5213..5938)
                     /locus_tag="LLB18_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244977.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            complement(6161..8281)
                     /locus_tag="LLB18_001985"
     CDS             complement(6161..8281)
                     /locus_tag="LLB18_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBK5244978.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            8511..9689
                     /locus_tag="LLB18_001986"
     CDS             8511..9689
                     /locus_tag="LLB18_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HBK5244979.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            9705..10463
                     /gene="aroD"
                     /locus_tag="LLB18_001987"
     CDS             9705..10463
                     /gene="aroD"
                     /locus_tag="LLB18_001987"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBK5244980.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            10486..10971
                     /gene="ybaK"
                     /locus_tag="LLB18_001988"
     CDS             10486..10971
                     /gene="ybaK"
                     /locus_tag="LLB18_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBK5244981.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(11042..12295)
                     /locus_tag="LLB18_001989"
     CDS             complement(11042..12295)
                     /locus_tag="LLB18_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBK5244982.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            12412..13761
                     /gene="gdhA"
                     /locus_tag="LLB18_001990"
     CDS             12412..13761
                     /gene="gdhA"
                     /locus_tag="LLB18_001990"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HBK5244983.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            13873..15219
                     /locus_tag="LLB18_001991"
     CDS             13873..15219
                     /locus_tag="LLB18_001991"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBK5244984.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(15527..15913)
                     /locus_tag="LLB18_001992"
     CDS             complement(15527..15913)
                     /locus_tag="LLB18_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBK5244985.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         5216 a         2844 c         3192 g         4686 t
ORIGIN      
        1 cttataattg gagtggtagt taattagtga cttatttttg attttatagc actgatacta
       61 taaaatatag atatcatcat attacacaat cttaatacta acttaaaaaa tatccctttt
      121 ataagtatgg tgataaaatc cgttccgggc tacctttttt aggtagccta ctttaatctt
      181 tatacctttc tggatcaacg aaagtatact tcaaatagtc ataacgccga tgatcgctcc
      241 gtgcgtctgg cacatcagtc acgatatcaa acaaaaaata cacatctttc ttcattctgg
      301 tttttgttgc cggaatttta aagtagttct tattagagta atagagattg attaataagc
      361 tatcttcgat tgctaaaaag aaaacttctg aatcccacac cttataaaaa tctttgacaa
      421 atctattcga aggatcaaat ttaaaccata attgtgtttt tccttccatc aacataatgt
      481 tcacctcaaa aagagtatac gaactaatgt tctttttgta aagtaggaat atcattgata
      541 atatggatgg aacatatata ttaaaaagtg ttctttttga atgctatttt gaatgccatt
      601 ttcattcatt taacgaaaat ctgcgaaaat aaaaaatgct caaaccctta taaaataagg
      661 atttaagcat ctagcgaaat ctgctgaaat ctcacaatgg agacggcggg agtcgaaccc
      721 gcgtccaaac acatcgccac ttaaaaatct acgttcatag tcaactcatt taaggattca
      781 ctttacagct tgccgagtga caggcattct gtatcgctag tctgatgttc tctttttcaa
      841 cttacagacg gaaagttgaa acgtatccca ctaaagttag gacccttact cgagcacatg
      901 ggcgatgccg agaggatcta cgctaactgt ttttaggcag ctaaagcgta agagttgttt
      961 tcgtttttag cagttatatt taactgtaac gtttttacgt agacgtaacc tacgaaacgc
     1021 aattcaagct cgactgtgcc tgtcgaatcc gtaacgtccc cgttagctaa caagggttac
     1081 gtgtattttt catacaaaat tagtatagca tatattggga taaattcaat aaaaaagcga
     1141 atcatatccc attatttata taataactgc ccctttctta agaaaaaata agcgattttc
     1201 ttaagaaaag aggtagcttc aaaaaaagat cttaaatcag atcaaaatac ttcaatgcgt
     1261 ggacaattcc gccttctgta tttttctttg tgataaaggt agaaagttct tttaatccgt
     1321 cataggcgtt gcccatagcg attttgttgt cgcaagcttc caacaaggca aaatcattcg
     1381 gaccatcgcc aaatccaaaa gtaggaactt tttccagctg aagttctttt tgcagacgtt
     1441 tgacacctgc cccttttgag attcctttct tcactgtatc gatcgagtaa ggaccattcc
     1501 gataaaaagt tagctcagga aaatgttcgt gatagtattc gtcacctgat tgagataaga
     1561 tcagcaacat atttactgtg ttttctttaa agcctaaagg atcaatttcc ggaacatctg
     1621 aatgaatgaa gtcgtaagca ttgatcattg tttggctatg accggtacac cagattttct
     1681 gatcgttata gtaagaaagt tcatgaccgt tcaactgtac atgatcatac attttttgac
     1741 attcttctga agaaaatgtt tgagaataga tttcttcgcc gtctactcga atgaaagaac
     1801 cattcatggt gaccgcagaa gtaatgcccg catcttccat gatagagtgg atttctgctt
     1861 ctgtacgtcc tgtagcgatg acggggagaa cattgttttc ttttaatgcg ttcatagctt
     1921 ttgccacttc gggtgtgatt tttgatttcg catctagtaa tgttccatca agatcaaaga
     1981 aagtgattgc acgataattt gacacaaata aaactccttt tttattggaa taagtttatc
     2041 ttaacaaaga atgaacaaaa gacaaacctt tcgtgaagaa ttcctgaaca tattggttca
     2101 gtcaacaatt tagagtatac tataagaaga gaatttagga gggaaagaat gatttttttc
     2161 agtattggta tcttattctt aataattggc agtctttttc ggattctgcc ctcaaaagga
     2221 aatctgcctt tttatgggta tcattcgcct cttgccgcaa aaacagacgc tcattggcgg
     2281 ctggctcaaa agacaagcgg aaactggttt tttcttatgg gcttactgat ggcattgatc
     2341 ggctattatt taaagacatc tgggcatacg aattattttc tgattgaaat gcttctgcta
     2401 gtatttccaa ttatgcctat ttttattatg acagaaaaga aattacagaa atatgacctg
     2461 gaaactggag ggaacgataa tgaatatttt aatgattgaa gataatcaat ctgtttctga
     2521 aatgatgcag atgtttttct taaatgaagg ttgggaagca actttcaagt atgatggaaa
     2581 agaagggctc gatgcctttt tagaaaaccc acaacattgg gatatgatta cactagacct
     2641 gaatttgccc acactggacg gtatgctagt aggaagagag atccgcaaag tttcaagtac
     2701 tgtgccgatt atcatgctga cagctagaga ttctgaaagc gatcaggtga tcggcttaga
     2761 gatgggggca gatgattatg tcacaaaacc tttcagtcct ctgacgctta ttgctcgaat
     2821 gaaagctttg catcgccgta gtgagttggc agaagcaaga gaagaagcag tagtttcaga
     2881 tgatcatttt gatatcgaga ctagtcattt caagatgaat acgaaaacac gagaagcgta
     2941 tctggacaac cggccaattg aaggactgac gcctaaagag ttcgatctat tgtttacttt
     3001 agcaaaaaaa ccacgtcaag tattctctcg ggagcagttg cttgaattag tctgggatta
     3061 tcagtacttt ggtgatgaac ggacagtgga cgcccatatc aagaaattac gacaaaaaat
     3121 cgaaaaggtc ggaccacaag tcatccaaac tgtttgggga gtcggctaca aattcgatga
     3181 ttctggtgtt gcctaatgcg ttatttgtat cagcaactct tagctttctg cggaatggtc
     3241 gcgttgatct tattgatcgt tggagtttct tttacacaac tgacaaaaca aacgattgaa
     3301 gaaaacaatt accagcaact gtttggatat gctgaatcag ttgaaaagac aacgcaaacc
     3361 tatgccgata cgctcccgca gtttagtcaa gatcaggcgt ttcaaaatgc attgctgctg
     3421 acagagcaag tactgacaga acaaaatgtg aactttatat ttatcgataa aaacgaacgt
     3481 gtcatttatc cgactaatac agctttactg aattttacct taacagctga tcaatggaaa
     3541 aatctgagga atggacgtca agaaaaattc acatcgaata aaaatatttt aggacaagca
     3601 caggcgacct cttacgcact tgtgccattt aatttgaatc atgaattcta tggagcactt
     3661 gtagttagtc aacctgcgcg aaatatcgat aacagcgttc gtccaattac actgaacctg
     3721 ttcaaaggat ttattttttc cagtatcgtt gcagttattg ccagctatgc ttttgcagca
     3781 ttccaagtta agcgtatcaa tcggttaagg aatgcgacga aagaagtgac gaatggtaat
     3841 tttgatgtac agctccccgt acatgacaaa gatgaatttg atgagttagc agatgatttc
     3901 aataaaatga cgaattcatt gaaagaatct caagcagaaa ttgaagaaca agaaaatcgt
     3961 cgaagacaat ttatggcaga tgcttctcac gagatgagaa cacctcttac gacaatcaac
     4021 ggacttctgg aagggttaga atacaatgca atccctgaaa atcagcgaga aaacgcgatt
     4081 aaattgatga aaaatgaaac agagcgtctg atccgtttgg tgaatgaaaa cttggattat
     4141 gaaaaaatcc gtacgaatca aatcagtatg gtcattaaaa aattcaatgg aacagaaaca
     4201 ttgaaaaata ttgttgcaca gttagaagct aaagcagaag cagcaggaga tacattgaca
     4261 ttgaaagccg ttgatgatat tgatgtttac gctgattatg accgatttgt ccaaatcatg
     4321 gtcaatatta ttcaaaacgc gatacagttt actgaaaacg gccaaatcac gattacttta
     4381 gaaaaaggct atcttgaaac gatcatcacg attgaagata cgggaattgg aatgtctgaa
     4441 caacaaatga aaagtatctg ggatcgttat tataaagtag atccttcaag aaaaaataca
     4501 aaatatggtg aatcaggatt aggtttacca atcgtgcagc aacttgtacg cttgcataaa
     4561 ggaaaattag aagtagaaag cgaactagga aaaggaacaa aattcgctgt tcgtttgcct
     4621 gacgtagaaa tcaaaaaaga gtaaaaaaca agcggtataa aagatcatga atcgatcttc
     4681 tataccgctt gtttttacta taaaatgatt gatttagccc gcgggctcta aacgatcaat
     4741 ataaggactt tgagcaatag tagcatcatg agtaaagagt aagatacctt gattttcttc
     4801 atgagctaaa taagaaagca agtggagtag ctcttggatc tccaatacac taagttcatc
     4861 aaatgtatct tcaataacaa tattgtttcg cttggaaagc aaggcatgaa gtaattgcag
     4921 ctttactttt tcaaaagacg tcaactcagc tgccgcacaa ttaagcaagg aaggagagat
     4981 atcaagtttt tcttgatagg ccaaacgatc ttgtttgatt tctttttccg gtacatccaa
     5041 caggacatgg tctttaagat tcagataagg aaacatcggc caattttttt ggatgatcgc
     5101 aaaattatcc agttttgcaa caagaacctc ttttttcaag tgctccaata ttttatgctg
     5161 tttttcgaga ggacacaaaa taacggtcaa gtgttcagca tgaatcaaat attcaggttt
     5221 cattacgtcc aggcctccta ctttgcaaat gatggataaa aaaagtgaaa gggaatagac
     5281 taagaatgag acagcatcca ctgagcccaa taagagtttg ggcaaatccc ttaagtatat
     5341 ctgtgaaaaa aagatcattt tggaaatcga tggtaaaaaa agtctgttga tccatcggaa
     5401 ttgtaagtcc gcttaccgaa gtcaagatat cacggatatc tggcagttca gtagtcttta
     5461 agacaagaaa attgatcctt tgaagaagcg cttcataaac tgactggaag cttacgatcc
     5521 acaataaaac caagatacaa caaagaaaga gaggaaagaa cagctgccag aaaataaaaa
     5581 ggaataattt ggttttagaa agaccagtca ggtgccaatt gatcaattcc tgcttgtttt
     5641 gcctgactga atagtaaaag aaaaagataa aaaggaaggc aaatagaaaa aataaactga
     5701 atatgccttt tatataaaat cggctagcta attctaaagc cggaagaagc tctgtagatg
     5761 cagaagcgcc aataaatgaa agccgatctt ggacttgatt ggctaaagcc gattgcaaat
     5821 ggtaaagagt caggcatgct atcaataaaa aagcagaaaa gcttgaaaat aaacaataga
     5881 gtattgtctg ctttttgtaa taaattaatc gagcagtagc atagcggatt attttcatac
     5941 ttttcacctc tataaaaagt atagaaaatg aatatgaata aagtatgaaa ttcctttagt
     6001 gaaatcacga attaaaacca gaaaatattt tgtaaaaagc aagaggttgt gaagaagctg
     6061 ccctattcta ttaccgtaga tgcaagcttt tgaacactgt ttattcgaaa agaggagcag
     6121 cgacaataat tttgtcgctg ctccttttaa atttatttta tcattcggaa gaacttgtgg
     6181 tcgttccgtg aagttcttgg tacgtttgcg ttttataaag atcaacagtt gattgtccgt
     6241 tgtgttcact aaagacacta gttgacttgt caccaagaga tttttcagct tcttttaatt
     6301 tctctaagcc attcttgtag tcataatcac tggtatcaat tgggtctaat ccactattcg
     6361 tatagaaccg aagaagatca ccattattga tttggtcaga aacagctaac tgtttatcaa
     6421 ctttttcttt cagtgaatca atttcattct gtacttcctc agtaggttca gtaatagctt
     6481 caccagtttc gttactatag atcgtaccac cgtagtaagt atattttggt gtaacaaaat
     6541 caccatcacg gaaagaaaca agctgttcat gatctttcga gaatagatct tgtcctaact
     6601 gaatataatt ttttgtatct acacctagta agtgaagtaa tgtaggcaag gcatcaactt
     6661 gtccgccgta agtgtgattg attccgccct gtgtttgtcc agggatatgg atcatataag
     6721 ggacacgctg catttgtgca ttgtcgtagt ttgtccaagt agaacttgtt tttccaacta
     6781 attcagctag atttttattt cttgaattcg agacaccgta atggtcaccg taaaggacga
     6841 tgactgaatt atcatacaag ccgctttctt tcaaataatt gaagaattct tgtacggcgg
     6901 tatctaaata attggctgtc gcaaagtaac cgttgatcgt ttcatcattt gtattggcta
     6961 acgggaatcc tgcttcgtca ttggtgaatt ttgaataagg ataatggtta gatacagcaa
     7021 tgaattttga ataaaatggt tgttgcagac gttccaagta ttgtacggat tgttggaaaa
     7081 atggtttatc atgcaacccg tattggaacg aattgtcatc attaacatca taataagaag
     7141 aatcaaagaa ataatcatat cctaaattct tgtatgtctc gtttcgattc cagaatgtac
     7201 cagcgttccc atggaatacc gcactaatgt aaccttgtgt ttgacttaaa atatcaggtg
     7261 cagcttggaa agtatttttt ccgcctaatt gtgtgaacaa ggagccttga ttcaagccaa
     7321 acaatgaatt ttccatcagc gtttccgcat cgcttgtttt tcctgctttt acttgatgga
     7381 aaaagttgtc aaaactgaac gtgctgttgc tgtggtaaag actattgatg aaaggtgtaa
     7441 cttcatgctg gagaccattc tcatctgtca atttataatc gatcaggaat tgctggaagc
     7501 tttctaaatg gatataaatc acattttttc ctctagcgag cccgaacaaa tcgtcatttg
     7561 gtgctgcata atgttctttt acataatttt ctacttcttt catatcattg ggacttgctt
     7621 ctgcccgcac ttggtttgtc tggtaagttt gaacaccgtc ataaaccatg aaagcattca
     7681 agccaagata tttgaccaaa taatcacgag agaatgttcg agtcagcaat tctggacgat
     7741 cagcttccgc cataaaaaga tttcctgaga aaatcataac tgctaatgta gagatcgcaa
     7801 aagccattct tgctcggatc gggcgagggt ccaacttgat tttttttgca atcagcagaa
     7861 cagtcaagat aataaaatcg atccaataga tcacatcata tgggcgaaac agtcgaatgg
     7921 cactttctcc cagaccactc gctactttcc cagcacctaa aatcgtgttg atcgtaatga
     7981 agtccgtgaa ttctcgataa taagtgacat tcgaaaaaac aagcaatgtc aaaagaaaat
     8041 aaatgaccat catcgtgata taagcaactc tagggcgtct gatataaaga gcaattccaa
     8101 gtaataacaa tgtagttgca atagggttga taaacaagat aaagtattga atgccacttt
     8161 cgattccgag atggaaatca actaaatagg caaaaatcgt tttcaaccaa agtaaaacga
     8221 ctagtaaaga aaaaaatccg agcctcttat tcaaaaaggc aggtgttttt atacatttca
     8281 agataatctt cctttctgca cttcttaatc acagaagtgt cctgaaacca tgttacacag
     8341 ctcacttatt ctcatttatt ttactagtat gacaatatag tgtcaattga aaccagaagt
     8401 ttatgctgtt tcattaaggt tttctttaag cttcatgaaa aaatgagcag taagacaagt
     8461 cctatgtttt ttgttatact tgggaagaga aagctaaagc aggtgaagga atgaaagtaa
     8521 aagtaaaaaa aagagcaagc aatcgattga aaaaaggata tccactgatc caaaaagaag
     8581 accttgctca tccccaaaaa gaaaccacgc aatgggtgga attagttgat tcgcaaaacc
     8641 aatttatcgc aaaaggatat ctaggaaagc agaataaggg aatcggttgg gtattgagcc
     8701 agcagaacat cccatttgat caatcttttt ttgaagaatt ttttgtgaag tcaaaagaaa
     8761 aaagaacttt ctttttttca gatgattcta ctaccgcttt tcgtatattc aatggagaag
     8821 gagacgggat cggcggtctg attgttgatt attatgcagg ttatgctgtt ttttcttggt
     8881 ataacgaaac gttatatgca catcgtgaat tattgattca agcttttcgt gaaatctacc
     8941 cggaaatcat aggaggctat gagaaaattc gatttgaatc agtaaatctg cctgagagcc
     9001 agttcattta cggaaaagag gcaccggaac ccttgatcgt aaaagaaaac ggagtaaaat
     9061 ttgccgttta tttaaatgaa ggattaatga ctgggatctt tttagaccaa aaagaagtac
     9121 ggggatcatt agcagaaggt ttcgcttctg ggaaaacagt tttgaacatg tttagttata
     9181 ccggcgcctt ttctgttgct gccgcaatgg gaggggcaat cgaaacaaca agtgtcgatc
     9241 tagcaaaacg cagtttaaaa aaaacacagg aacagtttga agtgaatggt ttggatgtcg
     9301 atcagcaaaa aatcattgtt atggacgtat tcgagtattt caaatacgcc aaaagaaaac
     9361 aatttttata tgacatgatt gtattggatc caccaagttt tgccagaaat aagaaaaaag
     9421 tctttcgcgt agcaaaagat tatggggaac tggtcaagga tagtctggat attttagcag
     9481 aagacgggat acttattgcg tctacaaatg ctgcgaatgt ctcgatagaa caattccaaa
     9541 caatgattga agaggaattc catgccaaaa atgtttcttt tgaacaactt gctttatatc
     9601 gtctgccaaa agatttccag acgacggata cctttttaga aggcaattat ctgaaagtgt
     9661 ttgtttatca aattaaaaat aaccattaga aggagcgatg cagaatggtt cgggtaaagg
     9721 gattgaatat aggaagcggt agaccaaaga tttgtgcgcc tcttatcggg gccgtccgag
     9781 aggaagtatt acgtgaagca gttcttgcac gtgaagcagg ggccgattta gtcgaatggc
     9841 gagtcgatca ttatcgtgaa gttttttctt ttgatgaagt agcagaaaca ttggttctta
     9901 tccatgagat gcttgatgga ctgccgttat tatttacgtt tcgtacctta gctgaaggcg
     9961 gagaacaaga catatcgatc cgtcagtatc gcgaccttta tgaacatgtg atacacacag
    10021 gattagtaga tatggtcgat atcgagttgt tcaaagtaga aagtctagga aaaagactga
    10081 tagaggaaat caagtcttta aacattcctt taattatcag tagtcatgat tttaaagaaa
    10141 caccagcaga ccctgtcttg ctttaccgat tgaatgttat ggaacatttt ggagccgata
    10201 tcggaaaact ggcagtaact cccaataatg aacgagatgt tttgcggttg atggagttga
    10261 ctagacgggc aaatgctttt gtctccatgc ctattattac gatgtccatg ggaaatcttg
    10321 gtaaaatttc tcgtctggtt ggcggaacga cgggttccgt tatgacattt ggttccttaa
    10381 gcagcgattc tacttctgct ccaggacaat taccggtcaa agcattgaag caaattattc
    10441 aattattaaa tgaaccgttg tagaacaagt ttgaggtgat attttttggc aaagaaaaaa
    10501 atagtaaaaa cgaatgcaat ccgtatggtc gaacaaaaaa agattcccta tacagagcac
    10561 gaatatgagt gggacgaaag ccacctaagt gcgtcatcgg tcgctgaaca gcttccagaa
    10621 agccaatctc gtatatttaa aacactggtt gctgtgggca atgtgacggg gcctcttgtt
    10681 gctgtgatac cgggagaagc cgaattgaat ctaaaaaaat tagcaaaagt ttcagggaat
    10741 aaaaaagtag aaatgctcca tttaaaagat ttggaagcaa cgaccggata catacgtggt
    10801 ggctgctcgc ctataggtat gaaaaaacta tttcctactt atttagatca aattgcagaa
    10861 agctatgaac aaatcattgt ctcggctggc agaagagggc tacagatgga gttagcacct
    10921 caagatatct gtgcattaac gagcggacaa tttgcagata taaaacaata aatcatacgt
    10981 ataaaagaaa gaaggaggcc gggatgttgt ttgtccagtc tccttctttc ttttttatac
    11041 attatgctct ttgcccggca ttcattcctg ctacatgccc tgtagcgaaa gccgctgtga
    11101 tattaaagcc gccagtataa ccattgacat ccagtaattc tcccgcaaaa tacagaccat
    11161 caatgatttt actctccaat gttttaggat aaatttcctt tagagaaacc cctccgccag
    11221 ttacaaatga tttctcaata ggaaaagttt tgttgattga tagcttaaac tctttgcata
    11281 gttgaacaaa atcttgaatt tgtttttgag aggcttgttg tcctgtcaga tgatccattt
    11341 caagccgctc aagaaagaaa actaacaatc gctcaggcaa tataccatgc caagcattga
    11401 ccaagttctt tttggttgct ttactttttt ctgtcaatat atgaataagc tcttgtttgg
    11461 tttgtgtagg gaaacaatcc agagaaagtg tcactggttc tcccgttttc tctaattctt
    11521 tattgacaaa acttgaacaa cgcagtgcag ccggaccaga aataccgaaa tgggtgaaaa
    11581 gtaaatccat cgtatgttca gtcaatacac gacctttttt atttaaaacg cgtaaagtga
    11641 tgtcttgtaa agaaagccct tgaagtgttt tctcctgaat atacggttca tccgatatca
    11701 agggggactc tgtcgcataa agaggcgtca ccgtgtgacc cactcgcttc acgatcttgt
    11761 acccatctcc agtagaacca gtagatggat aagtccgtcc accagttgtt aagataatgg
    11821 caggagcatg gaactcttcg aattccgtgc gtataccgta aattttatgt tctttgtgga
    11881 tcaatttctc tactcgagta gagaatagaa gcgtcacatc tagttctttc agacgattga
    11941 gcaatgcttc gataatcgtt tttgatttat ttgttacagg aaacatccgt ccatgatcct
    12001 cttcttttaa atgtacgcct tgtgattcaa agaagttcat gatatcgaaa ttattccatt
    12061 gcgcaaacgt actatataaa aactttccat ttccaggaat atgtgcaatc aaatcatcaa
    12121 caggacgatt gttcgtaaca ttgcaccgac caccacctgt catcagtagt ttttttcctg
    12181 cttttttgtt tttttcgatc aagagtacgc gtgcgccttg ttcagctgca ctgatcgctg
    12241 ccatcatccc gcttgttcca gcgccgacta cgatcacatc atacagtttt tccattccct
    12301 cacctcaagg aaagtgtagc atatctgaag aaagaaaaca gaaaaaaatg ttttgagcca
    12361 aaagagaaaa tgagctaaaa tgagggaaga taagcaaagg agcgtggaac gatgacaaac
    12421 gcaacagaat atgttcaagc aattcaagaa aagctacatc aaaaggatca agggcaagaa
    12481 gaatttttac aagcaatcga tgaattcatg cccacggtta tgtctttttt ggacactcat
    12541 cccgaatata tcgaaaagaa tatcttagaa cttttaacgg aaccagaaag agttattcaa
    12601 tttcgagtgc cttggcaaga tgatgaagga aactggcgag taaatagagg gtaccgtatc
    12661 caatacaact cagctatcgg cccttataaa ggtggattgc gcttccatcc tagtgtcaat
    12721 ctaagtatct tgaaattttt ggcttttgaa cagattttca agaatagttt aaccggtctg
    12781 ccaatcggtg gaggaaaagg cggaagtgac ttcgatccta aaggaaaatc tgataatgag
    12841 atcatgcgtt tttgtcaaag tttcatgctg gaattgtcaa aacatatcgg cccatcgatt
    12901 gatgttcctg cgggagatat cggtgtagga gctagagaaa tcggctattt gttcggcgaa
    12961 tataaacgat tgaaaaaata tgatactggt gtgttgacag gtaaaccttt ggatttttgg
    13021 ggaagtaaga tacgtacgga agctactggt tatggattag tgtattatgt caaacatcta
    13081 ttgaacgaag aaaaagattc atttaatcaa aaaacagttt ttgtttccgg aagcgggaat
    13141 gtagccattt atgcaatcga aaaagtgcaa gagctaggcg ggaaagttgt tacatgttca
    13201 gattctagcg ggtacatcta tgatccagaa ggaatagatg tgaaactatt gaaagaagtc
    13261 aaagaaatca atagacaacg tttgacggaa tacgcaaacc aacgtccttc tgctatttat
    13321 catgctggag aatctgtttg gacattgaaa gaaaaagcgg atatcgcttt gccatgtgct
    13381 actcaaaatg aaatagacga aagcttggcc gaaatcttag tagaaaatgg gatcaaaatc
    13441 gtagcagaag gcgctaatat gccatgtaca gtaaaagctg tttctgttct tcatgaagca
    13501 ggcgtgtggt attgtccagg aaaagctgct aatgctggag gagtagcagt atctgcttta
    13561 gaaatgagtc agaacgtcca gcgattgact tgggaaagag agcaagtgga tgagcagctg
    13621 gatcaaatca tggaaacgat ttaccatacg tgtcgccaaa cagcagccga gtacggcgac
    13681 gaaaaaaatc tgcttcttgg agcaaatgtt gctggatttg aaaaagttgc caaagcaatg
    13741 gcagcagaag gtttagtttg aaaaatgaaa ctttcttgga aatattgtca gcattttgtt
    13801 tatttgcttg aaaaataata aaaaaaaacg taaagtatta cctgtagagt aaacctataa
    13861 ggaggagaac aaatggcaca cattcatttt gactattcaa aagtagcacc gtttgtcaac
    13921 gaacaagagt tagggtacat gcaaagccaa gtaacagcag cccacaacga attacgggaa
    13981 ggtactggcg caggaagcga cttccgcggc tggatcgatt taccaacgaa ctatgacaaa
    14041 gaagaatttg cacgtatcaa agaagcagct aaaaaaatcc aatctgattc tgaagtatta
    14101 gttgttatcg gtatcggtgg ttcttattta ggcgctcgtg cagcgatcga cttcttgaat
    14161 cacacattct tcaatttatt agatagcaac acaagaaaag caccacaaat cttctttgcc
    14221 ggaaattcaa tcagctcaac atatattgct gacttgatcg aagtaatcgg tgatcgcgac
    14281 ttttcagtaa acgttatttc aaaatctgga acaactactg aaccagcgat tgcgttccgt
    14341 gtattcaaag agcttcttgt taagaaatat ggacaagaag aagcaaacaa acgtatctac
    14401 gctacaacag ataaagcaaa aggtgcagtt aaagtagaag cagatgcaga aggttgggaa
    14461 actttcgtga ttcctgatga catcggcgga cgtttctctg tattaactgc tgttggtttg
    14521 ttaccaatcg ctgttagtgg tgcagatatc gatgcattga tgcaaggtgc cgctgatgca
    14581 agcaaagcat actcaagcga caaactagaa gaaaacgaag cttaccaata cgcagcaatg
    14641 cgcaacattc tttaccgtaa aggcaaagta actgagttgt tgatcaacta tgaaccagga
    14701 atgcaatact tctcagaatg gtggaaacaa ttgtatggtg aatctgaagg aaaagaccaa
    14761 aaaggcatct atccttcaag cgcaaacttc tcaactgatt tgcactcttt aggacaattc
    14821 atccaagaag gacgtcgcaa tatttttgaa acagttgtga aggttgaaaa acctcgtaaa
    14881 tcaatcacaa ttcctgaaca agcagaagat ttagacggtc taggctactt gcaaggaaaa
    14941 gaagtggact tcgtaaatac aaaagcattt gaaggaacat tgcttgctca tacagacggt
    15001 gacgtgccta acttgctagt caaaattcca gaaatggatg cttatacatt gggttataca
    15061 atgtacttct ttgaaattgc tgtaggtatt tcaggttact tgaatggaat caacccattc
    15121 gaccaaccag gtgtagaagc ttacaagaaa aacatgttcg cacttctagg caaaccaggc
    15181 tttgaagatc ttgctaaaga attgaacgaa cgcctgtaag ataagggttt ttcgctagat
    15241 ttaaataatc agtgatagaa acatgttcgc tttaaaatga aaactggtac ccatttaggt
    15301 actcaaacat actgcatcgt ttattcagaa taaggggctg tgacaagacg tttgtcacag
    15361 tcccttgttt gtatagaaat cgattgattg ccttgctctt tagtttgttt taggacttta
    15421 agaacagtga ggctgacttc gaaggttaat tctgtttttt tgttttctag aatcagtaag
    15481 caaaaaagca ctcacttcga gtgctttttt gcgatatatt cttagcttaa gataggccta
    15541 atttttcttt tacagatgag ggtaccttat cgctggtaat tacttttttc tctatgatcc
    15601 gcttttcgct tgctttcaac tgcaagatcg ttccttcggg gtaagcagaa ccattggcag
    15661 agtcaccaga agtaatgaca tcgaaatcta actgtctttt ttcaccgttt tcagcataag
    15721 catctacgtt gtatttaaaa cctcttccaa ttacttcccc attatctgct ttgatatcag
    15781 tttctgcagg cattggagct ttgactaccg cataataatc tttacctaca taagtagact
    15841 gatagtagtc ccaacctttc catcctataa aagcaatcaa tatgataacg atcaacccta
    15901 aaattttttt catgaaagat ctcctttttt atttttat
//
LOCUS       DAFBSV010000066        15726 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.067, whole genome shotgun sequence.
ACCESSION   DAFBSV010000066 DAFBSV010000000
VERSION     DAFBSV010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15726
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.067"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(<1..1210)
                     /locus_tag="LLB18_001993"
     CDS             complement(<1..1210)
                     /locus_tag="LLB18_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBK5244986.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMNSVSGSMSFICVDGTTNQLFTILEDRRLYKLTQYFLRFPRKARLKVKYLV
                     MDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYR
                     RLKRYWKLLLKDSTTWEPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLR
                     YYFVKRGTEGFQETLKTISSTLPQSFKKKFTIFHCYQSGISNAFKVSHSNGVTEGLNN
                     KIKLIKRIAFG"
     gene            1483..3954
                     /locus_tag="LLB18_001994"
     CDS             1483..3954
                     /locus_tag="LLB18_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBK5244987.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(4057..5793)
                     /locus_tag="LLB18_001995"
     CDS             complement(4057..5793)
                     /locus_tag="LLB18_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBK5244988.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(5790..6494)
                     /locus_tag="LLB18_001996"
     CDS             complement(5790..6494)
                     /locus_tag="LLB18_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5244989.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            6625..7128
                     /locus_tag="LLB18_001997"
     CDS             6625..7128
                     /locus_tag="LLB18_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBK5244990.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            7088..7426
                     /locus_tag="LLB18_001998"
     CDS             7088..7426
                     /locus_tag="LLB18_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBK5244991.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            7447..8865
                     /gene="ffh"
                     /locus_tag="LLB18_001999"
     CDS             7447..8865
                     /gene="ffh"
                     /locus_tag="LLB18_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBK5244992.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            8977..9555
                     /locus_tag="LLB18_002000"
     CDS             8977..9555
                     /locus_tag="LLB18_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HBK5244993.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            9559..10080
                     /locus_tag="LLB18_002001"
     CDS             9559..10080
                     /locus_tag="LLB18_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBK5244994.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(10159..10713)
                     /locus_tag="LLB18_002002"
     CDS             complement(10159..10713)
                     /locus_tag="LLB18_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBK5244995.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            10966..11241
                     /gene="rpsP"
                     /locus_tag="LLB18_002003"
     CDS             10966..11241
                     /gene="rpsP"
                     /locus_tag="LLB18_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBK5244996.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            11253..11504
                     /locus_tag="LLB18_002004"
     CDS             11253..11504
                     /locus_tag="LLB18_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBK5244997.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDV
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            11629..12420
                     /locus_tag="LLB18_002005"
     CDS             11629..12420
                     /locus_tag="LLB18_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5244998.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            12590..13111
                     /gene="rimM"
                     /locus_tag="LLB18_002006"
     CDS             12590..13111
                     /gene="rimM"
                     /locus_tag="LLB18_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HBK5244999.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            13101..13862
                     /gene="trmD"
                     /locus_tag="LLB18_002007"
     CDS             13101..13862
                     /gene="trmD"
                     /locus_tag="LLB18_002007"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBK5245000.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            13998..14345
                     /gene="rplS"
                     /locus_tag="LLB18_002008"
     CDS             13998..14345
                     /gene="rplS"
                     /locus_tag="LLB18_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBK5245001.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            14603..14896
                     /locus_tag="LLB18_002009"
     CDS             14603..14896
                     /locus_tag="LLB18_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBK5245002.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
BASE COUNT         5222 a         2836 c         3188 g         4480 t
ORIGIN      
        1 aaccaaacgc aattcgttta atcagcttga tcttgttatt cagcccctca gtgacgccgt
       61 ttgagtggga caccttaaag gcatttgaaa tacccgattg gtagcaatgg aagatcgtga
      121 atttcttttt aaacgactga ggtaacgtag atgaaattgt tttaagggtt tcttgaaagc
      181 cttccgtacc tcgtttaacg aaataatagc gtaataattg acaaaaatga tacgcagttc
      241 gcaattcttc gttgtagctt aacagctcat caacgatttc tgtttgacta attggtcgtt
      301 taaacagtcg atgataatgc cgtttgagtg gctcccatgt cgtggaatct ttgagtaaga
      361 gtttccaata tcgcttgagc cgacggtact tcttctgatt ttcagagtgt gaggttcgaa
      421 aacgattcat gatctggaca cgtaattgat tgaagctgcg attgatgtgt tggacaatat
      481 gaaagcggtc agttacgatc tccgcatttg gaaagactgt tttaagcaac tgacaatagc
      541 tggcattcat gtccatcact aggtacttga cctttaaacg ggcctttcta ggaaagcgca
      601 ggaagtattg agttagtttg taaagtctgc gatcttcaag gatcgtaaat agctgattgg
      661 ttgtcccatc aacacaaata aaactcatgg aaccagaaac agaattcatt gatttgaact
      721 catccataca caacaccgtc ggaaggaagt tcatacgtgg ctggtaatgc ttcgttgctt
      781 cacgcaagat ccgtgtcacc gtcccatccg agacgaagta cttcttagcg attagtttac
      841 gtgattgatt ttcgtacagt tccatgagaa tcgcctgctt cagttccttt gttagttgat
      901 gatgttcatc aactaagtcc gttttcgcag aaaaggtcct tccacaatca tggcagagaa
      961 aacgggtacg ttttaattct aaaatagtta acttttcttt gactttcaac atctgagtgc
     1021 gtgtcgtata ggaaccgttg cggataatac gaaccgatcg acagtgttca caataggaag
     1081 aagagtcatc caattttcct ttaataaact gcgcttgaac gcctttatat tctttttcaa
     1141 tcagccattc ttcatcaaaa aataaatgtt tatctgttaa tccgagtaat tttctagtat
     1201 gattatccat tgagagactc ctttggtagg atgacgtttt ggtcgactaa attttaccaa
     1261 aagtgagtct ctttttgagt tgaaacgaag aaaaagtgtt agtagaaaat cgccttcgat
     1321 tttccaccaa cacaaaatat tatagaaccc tttttttttg ctatatgaca ggaatgaaag
     1381 gtgtttgcaa gcttaatgtg aggaacactt tccatatctg ttctatactg gataggagaa
     1441 gtttggaaat atccagaaaa cgaaatcaat cgaggtagcc acatgaagaa taaatggata
     1501 aatcgaagta aaaaaaagaa agtaacacaa agatcatcag ataaagtcat ccgtcttttt
     1561 ccatcgtata aagaaggatt aacggcagat caagtcaagg aacgaataga aaaaggtgca
     1621 gcaaataatt cagtcgatcc cacattcaaa acaaatcagc aaatcgtatt ggaaaacata
     1681 tttacgtatt tcaatttgat ctttcttatc ttagccattt tgctttgttt agtagaatcc
     1741 tataagaact tgactttttt accagttatc atagccaata caggaatcgc catttttcag
     1801 gaaattcgat ccaaaaagat cttggacgaa ctaaatgttt taaatacagc aaaagtcaat
     1861 gtcatacgag acgggataga acaaacaata gatatagaag accttgtaat agatgacatt
     1921 gttattttag agactggata tcaaattcca gcagatgcag aggtcgtgga agggaaactg
     1981 caagttaatg aggctttatt gacaggcgaa gcagatgaaa taaccaaaga aataggtgat
     2041 ccattaatgt ccggcagttt cattgtttcc ggaaaagctt acgcccgatt agacaaagtt
     2101 ggagcagatt cgtatatttc ccagctgaca gtcaaagcca agacaatggg agaaggagaa
     2161 cagtcggaga tgattgcttc tcttaatcaa ttgatcaaat ggattgggat catcattatt
     2221 cctatcggta tcctgctttt ttctcaaagt tactttttta atggaaacac gatcaaagaa
     2281 agtgtcgttg caatggaagc agcattgatc ggtatgatac ctgaaggact gtacttgctg
     2341 acgacgattg cattagcatt aagtgcgact aaactagcaa agcaaagagt tcttttacac
     2401 aatatgaaaa gcattgagac attggcaagg gtaaatgtcc tttgtgtaga taaaacagga
     2461 acgatcacag aaaataaaat gtctgttcaa aaaatgatcg tctctaaaaa acaagaaata
     2521 atcagtcagt cagatcaatt ggaagcatgc attgctgact atgcaaaagc gatggcagga
     2581 gacaatgcaa caatggaagc tgttaaagca tattttacaa aaaccactga tcaatcctat
     2641 caccatgtta ttcctttttc ttctgtccaa aaattcagca gtgtagcgtt ggcagacaag
     2701 gtgtatgttt taggagcgcc cgaaatggtt ttgcgcgatc aattgccgga atatgcggaa
     2761 gagtttgttt ctttcgctga aaaaggctat cgcgtgttgg tctttggtgt gtacgatggg
     2821 attcttgaag aaccagtatt gacagaagca gtcacaccat taggctatat tctgattgct
     2881 aatcctatca gaaaagaagc aagagccaca tttgattact tcaaaaaaca gcaagtagcc
     2941 atcaaagtga tttctggaga taatccgctc accgtatcca atgtagctgt ccaagcaggg
     3001 atttcacatg ctgatcagta cgttgatgca tctaaattat cagaagaaga atatgaagca
     3061 gctgtcgaaa aatatacagt ttttggacgc gtcaagccag aacaaaagaa aatcttcgtt
     3121 caattgataa agcgtaacaa tacagtagct atgacaggtg atggcgtgaa tgatattcta
     3181 gccatgaaag aagcagactg cagtatagcg atggcttccg gaaatgaagc cgccatgcag
     3241 gcctcacaag tggtcttact tgattctgac ttttcacgca tgccagaagt tgttgcagaa
     3301 ggacggcgcg ttgtgaacaa tattgagcga tcagccagct tgtttttagt gaagaatatt
     3361 ttctcctttt tgctctcact gttttcagtg atctttgctc tgacctatcc tttagaacca
     3421 tcacaaatca cattgattag tttgtttact atcggacttc catctttctt gcttgctcta
     3481 gaagaaaaca aaaagcgaat cagagggaaa ttcatcatga atgtgatgga aaaagctgtg
     3541 ccaggtggac taacagatat gatcgtagtc ggtgcgttgg tgatctgcgg ggtgactttg
     3601 aatctaaata aaacagatgt ttctacagca tctaccatgc ttttgattgc agtagggttc
     3661 ctcgttctct ataaaatctg ttcaccgctg aataaattca gaagtcagat cattcttttc
     3721 tgtgctagcg gtaacttttt ttcggtcatc tttttgcata agctgttttc aatcaccggt
     3781 atctcagctg tatcactttt gctgttgagc attctatttt tctcggcaga ttcgattttt
     3841 aggcatttga ccacattggt agaatatttg tttgaacgta aaaatgaaaa agagcaaaag
     3901 ccgtttagtc gcgtagctaa aaaatttcta tcgatattta aacgagaaaa ttgacgaaaa
     3961 gtatctcaaa aaagagtaaa aaagaacaac cactcgtgta tctttcgaag caggatgagt
     4021 catccaactt taaaacgcac gagcagttgc tcttttttac attttcggaa tggtaacggt
     4081 gaaagtcgaa cctgttccaa gatgactgtc tacagtaatc gtaccattaa ggagttgcac
     4141 gtagtctttt acaatcgcta accctaatcc ggtcccgcct gaatgtcggc ttcgcgcctt
     4201 gtctacgcgg taaaaacgct caaagatccg ttcctgatcc tcaatgtcga tacctatacc
     4261 aaagtcttgg acagaaaacg atagatcatc tgttgcctga tagcggataa taatctcgct
     4321 gtcgcttttt gaatattgga cagcattttc aatcagattt ttgataattg gataaaggat
     4381 atctgtttta gtagtaaatg gttcgttctt tccaatcaat cgaatcgtca accgtttctt
     4441 ttcgatgatt ggctgataat tttgaacgat ttgctggaaa taaggttctg tataaattgt
     4501 ctggatctcg taagaattct cgccatcttt tgacagctgg atgatttccc gaatcagttt
     4561 atctaaccgg atcgcatctt tttgcatgat ctcaagaaaa gaagtcagag tttgcgggtc
     4621 atcttttgca ccatccagta aagtctcggt aaaaccaatc agtgaagtca caggagtttt
     4681 taattcgtga gagacgttgc caacgaaatc cttttgtagc ttttctaaac gtcgcacttt
     4741 cgttaagtca tacgccaccc ctagaatctg tccggtacct tctgaattag taaagtagcg
     4801 caaactcaag tctaatgtct gccgaccttc tgtaagggtg atctcctgat ggatcagcgg
     4861 atgctcagga gtcacttgat gaatcagctg aatgagtttt ggctcttgaa tgacttctgt
     4921 gtaccgctgt tcaggttgat agcttaccac gtttaaatgt agctgcatct ttggattaag
     4981 cagtagtaaa cgagaatcag catcatcaat caggaatacg ccaatcatca gttcgttcag
     5041 taacgtatat aattgctctt ctgtggtagt acacgcccga tacatcttac tcatttgttc
     5101 gctcaacgca ttaatcgtct gatacaattc ttcccattga tcgggtgttt gcatgattac
     5161 ttccgcctga ttaggatttt gcaccatttt ttttagtacg ggcagcacgg ttttcaatgg
     5221 ctggtttttt tgatagatca gataatagat cattcctgca agaacaagga agaaagacag
     5281 aaagaagaaa aagacccaac ggcgaaaact ctcagttctc ggtaaaaaaa cgcttgtcgg
     5341 ttctgcgata cgtaaaatgg cttctaactg gccacttttt ttgactggta atgcgacata
     5401 taaaagatcc tcattcaaag tagtactttt gcgcaaagcg ctacctaggt tcccaccatt
     5461 caatacggct ttgatttcgg gacgggagtt tcgctgttca ttcaatgttt cattgtttgt
     5521 gtcaaataag atctttccag tagcatccat taaagtaatc cgttcgttcg actgatggac
     5581 gaattcttcc aaagcagttt tgttttgcgc tgcttggagg ttttcgacat ctaattgccg
     5641 gatcagcagt tgtgcttttt ttgtcaggta gctttcttgc tgttccacga tctgctgttg
     5701 aaaataatgg gaaatcaatt gccagccacc aaaaaacaaa ctaactaaaa gaataagaaa
     5761 gaagagacgt tcataaattt ttttccattt catcgtttgg gttcctgaaa cttatagcca
     5821 aatcctctaa tagtcaccaa gtactttggg tgttttggat ctcgctcgat tttttctcgc
     5881 aaatgactaa cgtgtacatc tacgattcgg ctttgtcctg cgaagtcaaa attccaaatg
     5941 cggtctagca atgtgtctcg gtcgatcaca cggtcttttc gtttcatgaa ataaacaagt
     6001 aattcaaatt ctttcggtgt tagttcaatc agatggtcgt ctacggtcac ttgataattg
     6061 gtcaaatcag cagtgatttg tccaatcgat agatattcag gctcagcttc atcttttgat
     6121 tgcttacgag gttcaattcg tctgaatatt gctttcatac gggctaatac ttcgcgagga
     6181 ctaaatggtt tggtcaaata gtcgtcagca cctatttcta ggccaatgat ccgatccact
     6241 tggtcatctt tagccgtcag catcaaaatc ggtgtttcat ttttttcttg acgcagccgc
     6301 tgagtgatct ccatgccatc catcgttgga agcatcacat ctaaaatgat gaaatcaaat
     6361 gattgttcta atgctaattc taatccttcg cctccatctg tggcactggt taccttgtag
     6421 ccttcttttt ccaaattgaa cgtcaagagc gttacaatag aaggttcatc atcaacaact
     6481 agtatttttt tcattcaaat ctcctttaaa taggtttcat tctgtttata ttttagcata
     6541 gaatcagtac aaagggctat tttacaaaag aaataaatgg tataatagga aggcactttg
     6601 ctgaatagaa aggaagagca gtcaatgatt ggaatcagtg catgtttagg cggtctggcc
     6661 tgtcgctatg atggacagaa aaaagaagta ccagaattga tggaactagt tgaaactgga
     6721 gaagctgtca tggtctgtcc agaagtgatc ggcggattac caattcctag agatcccgct
     6781 gaaatcattg gtggaaatgg attcgatgtg tggaaagatc aagcaaaagt atggacgaca
     6841 agcggcgaag atgtaacgga agcgtacaaa aatggcgcga tcaaagccta tcaaaaattg
     6901 caggaaaaac acattgatct agtcatcatg aaggaaaaaa gcccttcatg cggaacccat
     6961 tcgatttatg acggaagttt ttccggaata aaaaaaaatg gtgccggagt ggctactgct
     7021 tattttattc agcaaaaaat gactgtgctc tctgatgaag aatggctgaa aactagaggt
     7081 gagcagaatg gaaatcgaaa agaccaatcg aatgaacgcg ctctttgaat tttattcgac
     7141 cttattgaca gaaaaacaaa tgaactacat ggaattatat tatgcagatg atttttcatt
     7201 aggtgagatc gcggaagaat acgaagtaag ccgacaagca gtatatgaca atatcaagcg
     7261 gacaagcaag atcttggagg attatgaaaa aaaactccat cttttttcta attatattgt
     7321 tcgagaacag gtattggaaa atatgactgc atatattaca gataagtacc cggaagataa
     7381 aaaactactt gaatatgtac agcaaattca agcaatcgaa gaataaataa aaggaatgaa
     7441 gaaaatatgg catttgaaag cttaactgaa cgtctccagc aggcgatggg aaaaataaga
     7501 aaaaaaggaa aagtatcaga agctgacgta aaagaaatga tgcgggaaat ccgccttgcc
     7561 ttactagaag ccgatgttaa cttgcaagta gtcaaagatt ttactaagcg cgtacgcgaa
     7621 cgtgcggtag gggcagaagt gctggaaagt ttatcacctg cacaacaaat cgtaaaaatc
     7681 gttgatgaag aattgacgat cacacttggt tctgaaacag cagagttaaa taaatcacca
     7741 aaaataccaa ctgttatcat gatggctggt cttcaagggg caggtaaaac gacctttact
     7801 ggtaaattag ccaattattt aaagaaaaat gaaaatgctc gtccgctcct aatcgcaggg
     7861 gacgtatatc gaccagctgc gatcgaccaa ttgaaagtat taggtcaaca gctagacgtt
     7921 cctgtatttg atatgggaac tgaagtcagc ccggtagaga tcgtccgtca agggatggag
     7981 ttagcaaaag aaaagaaaaa cgactatgta ttgatcgata cggcaggacg tctgcatatc
     8041 gatgaaacat tgatggatga gttgaaacaa atcaaagaat tgacgcaacc aaatgagatt
     8101 ttgcttgttg tcgatgccat gactggtcaa gatgccgtca acgtagctga tagcttcaac
     8161 cagcaattag gtattacagg ggtcgtcatc actaaacttg atggggatac tcgaggcggg
     8221 gcagcactat cgatccgctc agtgacaggc gcaccaatca aattcatcgg ttctggtgaa
     8281 aaattgactg acttagaagt attccaccca gatcgtatgg ctagccgtat ccttggtatg
     8341 ggggatatgc tgacattgat tgaaaaagcg cagcaagact acgacgagaa aaaagcggaa
     8401 gaacttgcac agaaaatgcg ggaaaattca ttcgatttca atgactttat tgaacagctt
     8461 gatcaagtga tgggtatggg cccactggaa gatctaatca aaatgatccc aggaatgaat
     8521 caagtccctg gaatcgaaaa cgtcaaggta gatccaaaag atgttgaacg caaaaaagcg
     8581 atggtttatt ctatgacgcc agcagaaaga gcaaatcctg atctgttgaa cccaagccgt
     8641 cgtcgccgaa ttgctgccgg ttctggaaac agtgttgttg aagtgaatcg aatgatcaaa
     8701 caattcaagg aatcaagaaa aatgatgcag caaatgtcca aaggggatat gaacatccca
     8761 ggtatggacc aaatgtttgg ttcaggcgtc aaaggaaaac taggcaaaat ggcgatgaat
     8821 cgaatgatca agaaaaataa gaagaaaaag aaaaaacgga aataagatga aaaaaacagc
     8881 ttcggtacag actgaaaatg tctactgccg gagcttttct atcagcaatt tttattcttt
     8941 actaatacaa ttactctaaa cgaagaggtg gcacagatga gatgtccgtg gagtgaacaa
     9001 acagaaagta tgcggcaata tcatgatact gtctggggtg ttcctgaata tgatgaccaa
     9061 aagctgttcc gaaaattgat gcttgatatt aatcaagccg gattgagctg gcagacgatt
     9121 ttaaataaaa gtgaagcatt cgatgaagca tatgatcgat tcgatatcaa aaaagtcgca
     9181 aattatggag aaacaaaaat cagtgaacta atggaaaaca aaggaattat tcgtaaccga
     9241 agaaaaatcg aagcagccgt ccaaaacgcc aaagcagtct tgaaaattca agaagaaatc
     9301 ggcagttttt cagagtatct ttggtcgttt tctaatggaa aaatcgttga ttcttcttat
     9361 cattcacaag aagaagtccc aacaacaagt cctctttcag atgaattagc aaaagatcta
     9421 aagaaaagag gatttaaatt tatcggaagc acaacaatct atgctttttt agaagctgtc
     9481 gggatcatca atgatcacct tgacagttgt ttccgcaaag aagaggtcgt acgtatcggc
     9541 agaaagggcg aataaagcat gcgaaaaatc atattttatg gtgctataag tttagatggc
     9601 tatttggcaa cgaaaacgga tgatcttcaa tggctttttg acactccaac aggtaagcaa
     9661 actacttatg aagcttttta tgaaacaatc gatacgacca tcatgggcag aaaaacttat
     9721 caggaagcaa aaaaatattt ggagaccgaa gcaatttatc cagagaaaaa gaatttcgtt
     9781 ttttccaccc acgcacaatt acaattgcca gatgctgagg tcgtaaacga agatcctgtt
     9841 gcttttctaa aaaatctaca aatgacagaa ggaaaagata tctgggttgt gggtggcggt
     9901 cgattgatca aaccgctatt ggaacatcaa atgattgatg aatggtatat ccagattacc
     9961 cctgtattat taggggacgg gattccttta ttccaaaaag gaacatatga agcgcgtttt
    10021 gaaatgctag acacgacacg attcggtgaa tttatcgaat tgcattatgt acgaaagtag
    10081 aagtaaataa aataaaaaag gcaactatat gcagaaatgt cctgtacata gttgcctttt
    10141 ttattaccgt tatgcttttt actctgttaa tttgttagaa aaatctagat acgcatctaa
    10201 aatcgtttgg aagaaactta atgttccttc aacgatatta ccattttcat caattagatt
    10261 cgcaacgttt ccgatatatg cttccggttg ctgcaaggtt ggcacattca aaaagacaag
    10321 tgattggcgt agatggtggt ttgcgccaaa gccgccgatc ccacctggtg atgcagtaac
    10381 gactaaacct ggtttatgat cccaaacact gtgtccataa ggtcttgagc ctacatctaa
    10441 agcatttttc aatactgctg gcacagaacg gttgtattca ggagtaacga aaacgacacc
    10501 gtctagtccc ctcacttcct cacgaaaacg agtccattca gcaggagcct gttctggagt
    10561 ttcgagatcc tcattgtaaa atggcagatc atcgattttt acaaatacac tttcgtaccc
    10621 ttcaggaagc aatttcgcaa aagcttctgc tacttttttg ttgtaagaat cttttcttaa
    10681 actaccaata aaaaatccaa ttttttttgt catacgattt ttcctccttc aaactatcta
    10741 taataatctt acaaaagata agtaactgga gcaaataaaa acacttactg acaaaagcta
    10801 catagaagat agattactta tttttaacaa aaaagaagtc taaaatcttc tattttctaa
    10861 aaaaaatcga atttaatcaa gctgtaaaga aaaaaagctt tacagggtaa aaaaaaactg
    10921 ttacactaca tcttgtgaat aaaacaatgg aggtggaaat aaataatggc agttaaaatc
    10981 cgtttaaaac gtatgggttc taaaaagagt ccgttttacc gtatcgtcgt agctgattca
    11041 cgttctcctc gtgatggacg tttcatcgaa actgtaggta cttacaatcc tttgaaagac
    11101 cctgcagaag tagttttaaa agaagactta gttcttgact ggttatcaaa aggtgcacaa
    11161 ccttctgaca ctgtacgtaa catcctttca aaagaaggcg ttatgcaaaa acaccacgaa
    11221 gctaaattct caaagaaata aggtgaccgg atatgaaaga tttaagcgac ttagtcttaa
    11281 caatcgttcg tccgctagtc acttatcctg atcaagtcaa gttagacgtc gtagagtcga
    11341 aagactttta cgagtacaat ctaacagtgg ctcctgaaga tgttggccgt atcattggaa
    11401 aacaagggcg tgttgctaaa gcaatccgca caatcgttta cggtgttcgg atcaatgcac
    11461 cgaaaaaagt gcgtttgaat atcatcgatg ataaggaaaa gtaaataaac gtgctgtact
    11521 cgaattttcg agtgcagctt ttttgttttt tttattaatt gaagaaatga ttatttggca
    11581 aaacaagcaa gaaagcgtat ccttatagga ggagggagtg aacagccaat gagaaagaaa
    11641 atgttattta ttccatttgc tctattgtta agcgcttgta gttcggttac tcaagaatca
    11701 gacaatacac atctatcaag cagtatatct gaaactgtta ccagtccaga aaaaagtagt
    11761 accaaaacgg cttccaccac tgaacaaaca atggctacct caaataatga gaaaaagact
    11821 gctttagacc agttgaaaga acaacagcca aatgttccca tgcctctaga tgtaccagtc
    11881 tcttcaggct atctcaatat cgcagcgaca catacaaagc aaggttattc tattttatat
    11941 tacagaacag atcgtcccct cgggttgaat gctgacgaat tgaatcaaga aacgcctatt
    12001 gcaacctatc tatatcaata tgggtttgct tctagtcaag aaacaatcca agttttgcag
    12061 ccatttgaga tcgacacaaa tggtcagcaa gtggacttag gttctcgaat cacagggtat
    12121 cagcaaggtg cagcaggttc aagttttctt gaatggcaag aaggaaactg gcgtattcga
    12181 atccgtggga ataatataga aggccaagat cccttactat tagctaaaga aatcgtagct
    12241 tatttggaag aaaacagtct accagcacct gaacaatttg gtaaaattac tgttgatatg
    12301 ggtgatacga cgaatcgagc cgtagaagta agctggcaag aaccgaaaaa tgcctatacg
    12361 atcactcatc aagatcctat gtctgcgttg aagatggcag tttctatgaa gaggttgtga
    12421 aatcagcgcg ctgatctgag cccatcattt aactccaagt cacaggaagt aatcaaaaat
    12481 agcacgccgc atttttgcat aattttggct taatacctta aaagaaaact agaattgcct
    12541 cttcacacat gctaaaataa aacagacaaa aaagaaatgg ggatataagt tgactgaata
    12601 cttgaatgta ggaaaaatcg taaacacaca aggtatcaaa ggcgaagtcc gtgttatctc
    12661 aacaacggat ttcccagaag aacgttacaa aaaaggaacg gtgctaacac tattccaaga
    12721 cggaaaagca cctgtggaat taacagtcaa aagtcatcgc aaacataaaa attttgactt
    12781 attgagtttt gaaggacatc cttctatcaa tgatgtggaa aaatatcggg atggcatatt
    12841 aaaagtgtca aaagacaact ctgtagatct agctgaaaat gaattctatt accatgagat
    12901 catcggtctg catgtattag aagatggaac tgagttaggt aaagtaaaag aaatcttgtc
    12961 accaggtgcc aatgatgttt gggtcgttca acgtccgaaa aaagctgata tattgcttcc
    13021 atatatcgct tctgtcgtca aagaagtcga tttagaagct ggagtggtcc gtgtagaaat
    13081 tccagaagga ctgattgacg atgaagattg atgtattgac tttatttcca agaatgtttg
    13141 aaggtcctat gggggaatcc atcatcggta aggctgtaga taaaggatta ttagatatca
    13201 atatctctaa cttccgcgat tattcagata acaaacatca gacagtagat gattatccat
    13261 acggcggtgg agcaggtatg ctgctcaaag tccagcccat ctatgataac atccaagcca
    13321 ttgaaaaagc tgcaccggat gtcaaaaaaa gagtaattct tcttgaccca gctggtaaac
    13381 gattcgatca gaaaatggca gaagaatttt cacaagaaga acacttagta ttcatttgtg
    13441 gtcattatga gggatatgat gaacgtatcc gcacattagt gacagatgaa gtttccttag
    13501 gagattatgt ccttactggg ggagaattag gtgcgatggt catgatcgat gcaacagttc
    13561 ggcttttgcc agatgtgtta gggaatcaga cttcagctca aacggattct tattcaaccg
    13621 gtttattgga acatccccaa tatactcgcc cggcagaata taaagggatg aaagtaccag
    13681 aagtattgac aaatggaaat cataaattga ttgaagaatg gcaattaaaa gaatcactaa
    13741 gaaggaccta tcaacgtcgg cctgatcttt tggaaacact tgaatggaca cctcaaatga
    13801 cgaaattttt agaagaaatc aagaaagaag aacaagaaaa aacagcagat gaagccaagt
    13861 gactttttct aaaatcttct ttacagtagg ttgataatat gttagtattt tatggtgagt
    13921 gcaaaagcac ttaactatta cgatattccg ctgtgagaaa agctcataag aatatttgga
    13981 ataaggagaa gaaaaccatg aatccattaa tcgaagaatt aacaaaagaa caattacgtt
    14041 ctgacatccc agcgttccgc cctggtgaca ctgtgcgtgt tcacgcaaaa gttgttgaag
    14101 gtactcgtga acgtatccag ttatttgaag gtgttgttat caaacgccgc ggtgctggaa
    14161 tcagcgaaac ttatacagta cgtaaagttt ctaacggagt gggcgttgaa cgtacattcc
    14221 cattgcatac accacgtgtt gcaaaaatcg aagtagttcg ctacggtaaa gtacgtcgtg
    14281 caaaattgta ctacctacgt gcattacacg gaaaagctgc tcgtatcaaa gaaatccgtc
    14341 gttaatcatt gttatcagac tgagaaagaa cccttggtat tcaagggttc ttttttctta
    14401 gcatgtaatt tgaacaccct gatccagttt tttctttaat tattggtagg ggagaataat
    14461 ggattagaat aaatctacct ataagtagta gtaaaaaaaa gagcactatg ataatatctt
    14521 tcttaagagt aaccgcttta ataaaaaatc cagaatattc taacataaat ggagtattct
    14581 tagaatcaaa aggagaaaga agatggttta tacttatacg gagcaagaaa agatgaaagt
    14641 tttagacaca ttcatgaatg atggaaaagt aaaacaagta ccaagttcaa caaaaaagaa
    14701 atacatccta ttgaaagaag tcttgaaacg ctttgaccat ggagtgactt atacagaaac
    14761 agaggttaat tcgatactgc tgaacgtatt ttctagtggc gattatgtcg aacaaagacg
    14821 ttatctaatc acatttggct ttttcaaaag aagttcagac ggtcgggcat atcagatgat
    14881 gggaattgaa aattagaagt tttaatttat actcattgaa aaaagttcaa gtatgcgata
    14941 ttggttctac accgcatact tgaacttttt ttgtcatctg tatctataat acaaagccaa
    15001 gaacgttatt caaaatatgg atagctatga taaaagctaa tgagcgattc gcagttaaat
    15061 aagcaatcgt cagtaaaatc gttccaggag cgtacatgaa aaaatcaatt ggatgcgtta
    15121 catgaataaa gataattctc ttttatttgt acgaataaat accaaaacgt acctcctaaa
    15181 attagatttt ggacagatgc cctttaaaaa gataacaaga tttcgttctt gaaacaatat
    15241 atatgctttt attccaatga ggttgtgaaa acagtatttt gtcctgagcg ttagaaaatt
    15301 gaaaatgggg aatagcaact cgtactttac cattttttaa gtgaatacaa gatcagctaa
    15361 ttgaacaccg tttattcgtg atgagggaca caacactgca gtcgacacat ttctctttta
    15421 tgttcaaaga taacaaatat ttaaaacaaa gaaaaatagt agataatccc gtcctaactc
    15481 ttttattctt ccctcatagc ttccaaattt aagcaatact tcaattaatc aagttttatc
    15541 tttttttttc aataatcgta aaaaaagagt attttttatt taaaaataaa atctttgtat
    15601 taaaggacaa gactaaaata accttagaat aaaaagagaa aaaaagcccc aaactttcta
    15661 tacatcaata aaataataaa aattaaattt agaataacgt gtaaaggatt atttgatgat
    15721 ttttta
//
LOCUS       DAFBSV010000067        15272 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.068, whole genome shotgun sequence.
ACCESSION   DAFBSV010000067 DAFBSV010000000
VERSION     DAFBSV010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15272
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.068"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(47..1513)
                     /locus_tag="LLB18_002010"
     CDS             complement(47..1513)
                     /locus_tag="LLB18_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBK5245003.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1900..2496
                     /locus_tag="LLB18_002011"
     CDS             1900..2496
                     /locus_tag="LLB18_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBK5245004.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(2554..3036)
                     /locus_tag="LLB18_002012"
     CDS             complement(2554..3036)
                     /locus_tag="LLB18_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245005.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3142..3339)
                     /locus_tag="LLB18_002013"
     CDS             complement(3142..3339)
                     /locus_tag="LLB18_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245006.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3634..4392
                     /locus_tag="LLB18_002014"
     CDS             3634..4392
                     /locus_tag="LLB18_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBK5245007.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4452..4880
                     /locus_tag="LLB18_002015"
     CDS             4452..4880
                     /locus_tag="LLB18_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245008.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4926..4998
                     /locus_tag="LLB18_002016"
     tRNA            4926..4998
                     /locus_tag="LLB18_002016"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4959..4961,aa:Gln,seq:ctg)
     gene            complement(5148..5519)
                     /locus_tag="LLB18_002017"
     CDS             complement(5148..5519)
                     /locus_tag="LLB18_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBK5245009.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5734..5919
                     /locus_tag="LLB18_002018"
     CDS             5734..5919
                     /locus_tag="LLB18_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245010.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(6002..6190)
                     /locus_tag="LLB18_002019"
     CDS             complement(6002..6190)
                     /locus_tag="LLB18_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245011.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6214..6477)
                     /locus_tag="LLB18_002020"
     CDS             complement(6214..6477)
                     /locus_tag="LLB18_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245012.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6635..6892
                     /locus_tag="LLB18_002021"
     CDS             6635..6892
                     /locus_tag="LLB18_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBK5245013.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6963..7154)
                     /locus_tag="LLB18_002022"
     CDS             complement(6963..7154)
                     /locus_tag="LLB18_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245014.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7295..7615)
                     /locus_tag="LLB18_002023"
     CDS             complement(7295..7615)
                     /locus_tag="LLB18_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245015.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7638..8072)
                     /locus_tag="LLB18_002024"
     CDS             complement(7638..8072)
                     /locus_tag="LLB18_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBK5245016.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            8407..9045
                     /locus_tag="LLB18_002025"
     CDS             8407..9045
                     /locus_tag="LLB18_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBK5245017.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(9369..9452)
                     /locus_tag="LLB18_002026"
     tRNA            complement(9369..9452)
                     /locus_tag="LLB18_002026"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9416..9418),aa:Leu,seq:cag)
     gene            9980..10480
                     /locus_tag="LLB18_002027"
     CDS             9980..10480
                     /locus_tag="LLB18_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5245018.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            complement(10670..11014)
                     /locus_tag="LLB18_002028"
     CDS             complement(10670..11014)
                     /locus_tag="LLB18_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HBK5245019.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(11168..12088)
                     /locus_tag="LLB18_002029"
     CDS             complement(11168..12088)
                     /locus_tag="LLB18_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBK5245020.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            12275..12766
                     /locus_tag="LLB18_002030"
     CDS             12275..12766
                     /locus_tag="LLB18_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HBK5245021.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            complement(12790..15165)
                     /locus_tag="LLB18_002031"
     CDS             complement(12790..15165)
                     /locus_tag="LLB18_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HBK5245022.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
BASE COUNT         4771 a         3031 c         2479 g         4991 t
ORIGIN      
        1 acaggaactg ctgcaaataa gcaattcctg tttttatgtt cattgattaa tgaatagagc
       61 ccattagttt tttgattggt tctttcacag taaatagcaa gataccaccg acgattgcta
      121 ctgcaccgat aataccgaag taagcagatt ctgttcccgg tgtgtagaag cgtgcaattt
      181 gtgcattgat tgcttgtgaa gaagcatcag ctaagaacca aatagcgatt gtttgtgatt
      241 caaatgctcg tggtgctaat tttgttgtca cagacaaacc aactggtgaa agacacaatt
      301 cagcaataac cacgatgaag aaacttccca acaaccacaa tggacttact tttccacttg
      361 taccataaag catacccggc aacatcaata gcaagtacga taatcctgca aataaaagtc
      421 caagagagaa tttcactact gtagatggtt gacgttcacc aagtttcgtc cacatcgtta
      481 cgaatactgg tgtcagaata aagatgaaaa ttggattcaa tgattgatac cagcttgctt
      541 ggatcgttac accaaatagc gtagattgtg tacgttcact agcaaataaa gctaagatag
      601 atgaaccttg ttcttgtaat gaccagaaaa tgattgctgc aaggaataat gggatataag
      661 cccatactct tggtttttct tcagcagtta catcttttga agtcagcatt ttgataaagt
      721 aatacaacgg taagataatc cccaatacac tgattgtatt gacaaaaaag tcaattgtca
      781 gatgaccagt tagttgtgcc ccgccgaata ctgcagcgat aacaacaagt gcgatgatca
      841 agttacggat gaatccttta cgttcttcag ttgtcaaagg attcggcggt gttgtaccca
      901 ctccgtctaa tgtcttgcgt ccttggatga tgtattgtaa taatccaaag aacatcccaa
      961 tagcagctaa agagaaccct aaatgatagt tatattcttg accgattgta ccaacgatta
     1021 gtggtgctaa taatgcccct aagttgacac ccatgtaaaa aatcgaaaat cctgcatctc
     1081 ttcgcaagtc agtctttgaa taaagatgtc cgaccatgcc agaaacattt ggtttcaaaa
     1141 aggcggttcc gataataatc aatgccatcg aaacaaacaa tgtacttaca ccaaatggta
     1201 aagccaagac gatgtggcca agcataatga aaactccacc gaagaataca gtgcgttttg
     1261 ctcctaacac tcggtcagat acccatccgc cgacgatact agacatgtag atcaaagatc
     1321 cgtagatcga catgatagct aatgctgttg ctcgtggtaa tccaagtccc ccgttggcaa
     1381 ctgtatcgta catataatag ataagtaatg cacgcatacc gtaataacta aatcgttccc
     1441 acatctcagt gaagaacaaa gttgacaatc ccttcggctg cccgaagaag cccttgtctt
     1501 gctgtttttc cataatctat accccaattc tttaaatttt cagaaaatat tatacatctt
     1561 taccgaaaaa tttaactaaa aaacttattt aagaaatata aactaatttt ctataaaagc
     1621 aagtaatttt taatggcaat atcataaaaa aaagaagata gagatttaat aattatatat
     1681 cagctgtttt tttcaaataa gcaaaaattc ctaaaacaca acaatgaaag cgataactaa
     1741 gaaaatcctt acataacgat ttttcttatt aaaattgttt tttgaacttc gcttattttt
     1801 tgtgagcata tctgtttact tactttttgt aaggtgctat acttcatttc gtaatcaatt
     1861 aaaaaaatgc aaaacgcaaa tcaaaggaga aattttatta tgacaacttt tactgacact
     1921 ttgaaaaacc gccgttcaat ctatcatcta ggacgtaatg tttcactttc taatgaagaa
     1981 ttaacaactt tgatcaaaga agcaattaaa gaaagcccaa ctgctttcaa tgctcaatca
     2041 acacgcgcag ttatcctttt cggagatgca catgaaaaac tttgggaaat cactgaagaa
     2101 gcacttcgcc cattgactcc agcagaagct ttcccaaata cacaaaacaa attagctggt
     2161 ttcaaaaatg gttatggtac agtattattc ttcaaagata ctgacgtggt aaaaggtcta
     2221 caagaacaat ttgaattata tgcagacaac ttcccagatt ggtcagaaca atcaaacgga
     2281 atcgcaacag ctaatacttg ggtagcatta gttgataaag gattgggcgc aaacttgcaa
     2341 cattacaacc cagttattga cgaagcagtt gcaaaagaat ggaatatccc ttcaaactgg
     2401 aaactacgtt cgcaattagt attcggttca ccagaaacac cggctgggga aaaagaatac
     2461 atgaacgatg ccgatcgctt ccgcgtattt ggataatttt atttgaaata aaaaacagag
     2521 gttgtgacaa acatcttgtc gcaacctctg tttttattct ggatcaatca taatatcaat
     2581 ctctgcctca tcgtttaagc gttgggacaa aaatggaact aattcttcta atgatgcaga
     2641 aaatttcagc atcggtcctc gccatccgtt tcggaaaaaa ttcattttta cgattttaga
     2701 accttttggc tgatataata caattttatt gatctcagaa aaaggaacac cttttttgtc
     2761 aaagctattc aaaacaagtc cttcttctgt gattcctcta ctgtccaaca aaaaactaat
     2821 aaaaatcatt gctgacaaga tcccttttgc caattcatct gctgtaggat gactgatgag
     2881 tgtataccaa atgactagtg acactaagaa gggtatcacc aagtagaccc atcgatttcg
     2941 cacagtccga taaataattt cttttcgaac cagccaaaga aataaaaaca tcacaacaac
     3001 gaataaaaac aatagaaccg taaagaatgt taccatgaca actcgcctcg ctttttcttc
     3061 tccagaaaat aggaaaagaa tactgattta ccttctcaaa gaaattggac ttgcagcacg
     3121 ccgcacgtcc aattgttttc tttattcaaa tgtatcatat tttgcaacaa ccatgcttgc
     3181 tttttcatct aataattctt ggtcctctgc agcacattgg gcaactttga ccacggcgca
     3241 gtttgtcatt tttgatacaa cttcaccaat gaccgttttt gtaaaaccaa ttggtttgca
     3301 tgcatattgt tctcctaaat taatcatttc ttccgtcatc aaaatcctcc taaactgctg
     3361 gaacttttct ccacattacc actgctattt ctttggagat ttaactcatt gatttttatt
     3421 tacagttaaa aatcaacctt acaggcatta tagcgtactg ttttcgtttt cacaattaaa
     3481 acagctgttg tatttagaag aatttttttc aaaaaattaa aacatattcc ttaaaaacta
     3541 attatttcct acatattaaa atataatact tccatttcca ataaaaatac atttataata
     3601 ggaaagataa acagctgaaa agggagattt caaatgaaga aaaaaacgtt caaaaaacta
     3661 ttgtttctag ggggcacagc tgctctttta ttaagcggta caagttatta cctacatatc
     3721 cattctccag aacatacaat gaacactgca caaaaaagtt caacacaaaa aacgaaaaag
     3781 acaaaagaga aagcagaagt tttactagat gttccattag agagccagtt tgattctcct
     3841 tctttagaaa atggctgtga agtcacttcg ctttctatgc ttttatcttt ttatggttat
     3901 gaaacaacta aaaaccagtt agctgagcaa ttggattacg tccctgtttt caatgcagat
     3961 gggactcatg gcgatcctaa tgaaggattt gttggtgata tcagtggcgg agactgggct
     4021 atggtcgtct atgttccccc agttgcctcc cttgctcagc aaatcgtcca aacggattat
     4081 cacacttttc caaaaaccga tgctcaactc gatgatatca aaaaagcact atctaaagga
     4141 aatcctgtct ggacttctgt gactatcaat tttgaagtcc cagatgaaac tgattttatg
     4201 acttggacca caaataatgg agaagtaaga gtcactcctc ttgttcatgc ttgtgtagtc
     4261 actggatatg acaaagaaaa tatttatgtc aacgatccct atggtgtaaa aaatcgagca
     4321 gtaccgatca acgatttttc ggcgattttc actgcaatgg gtggacagat gctaactttg
     4381 gagaaaagct agtaattcaa acaaaaatcc cttatactca agataccaaa cctttgaagg
     4441 gagcgtagat aatggaaaaa ttcacacata aaaaaatgga tccaaatgaa attccgatta
     4501 tttttgtccg tgactgcaag ggaaatgttc aaggtaaagt ctctattaat gagtggaacg
     4561 agcgtcgcag acctgctacc ctcaatgaac tggaaatcaa attgtatcgt caatctcttg
     4621 tttattacgc agatcaagag tacgagaaag ccaccgattt attgaaattt ctaattgctc
     4681 gaacagagta tactcgcttt gaatatattg aacgtttagc aaacatctat catattatga
     4741 atgaacctgt caaagaatat cagttattgg acaccgtctt gtcagtagca gaactgattg
     4801 cccttcctgc tggattagaa aagaaactag tacgccgcct tttacgagta aagcaacaac
     4861 tatccgatca agaaaaataa cttgcgtttt tttaggaaag tgctatgatt attttgttga
     4921 ataaatggga tgtagccaaa ctggtaaggc acttgactct gaatcaagca attgtaggtt
     4981 cgaaccctgc catcccaatt tgatgtgctt gctgaaaaaa tgaaccccct gtaaaagaac
     5041 aatctttttg cagggggatt attgtattat ttttactact tgtatttagt ttacataatt
     5101 aaattatgaa taataaaatc gggcgtattc ttaatacaaa aactgattta cccaataatt
     5161 gctaatgctt tctccggaac tttttctcta ggaacttcct catacgtttc tatgtgtgct
     5221 cctttattgc taattttcaa ataatgattt tcttttaaca cagaaagacc attaaattca
     5281 accgttcgtt ctttcccatt ggcatcagca gctttctgca cataccttgc tgtaccatat
     5341 tcatttactt cctctggttt ttgtgtcttt acatagacct ctcctttttc aactaatgga
     5401 tttagctgat caagtatacc agggatttct ccataacttc cttcagtata atatttcagt
     5461 ccaaatagca aaataccact aatcgccgcc agtccaatca aatatttaat cactttcatc
     5521 tttctacctc cttgttatat attcagtata tgggtcagtt aaagaaattc catccgtccc
     5581 aagttggaga tttttctcct actttagaag cgagaatcga gtgttttttt agtaaaaatg
     5641 atcgttattt gatattattg acgtgtggat aaatcagttt ttctcgtttt gtccatgtaa
     5701 aaaatcatgt tgatagcaaa ggatgtgttc aaaatgaatc aagaagaatt atttcaaaaa
     5761 gtcaaggaaa tgattaagaa cggcaatttc gatggcgcaa aacgatttat cgaagaacat
     5821 aaagaacaat taggacctta taaagagaaa gcccaaaatc ttttaaaaga tgtaaatatc
     5881 gacagtgtca aaaacaaatt taaaaatcta ttcaaataag taaaactttc acttttgtaa
     5941 aatcaaagga ggacaatgct gctgcatcgt cctcctttgg ttcttttctg aatacttcat
     6001 actaaaataa acgtgtcgga tcgtaatgat aagtcacatt gccgttcagt gaggcttttc
     6061 ccaccacata tttacgattc tccaacttca gccacgcttc tcgaaaagcc attaattctt
     6121 ctctttttac atcaatcttt tcgatttttc catcgatcaa atcttgaata agttgttcat
     6181 atggattcat ttttttcctc catctgctgt caatcaataa gttgtaaaaa taggttcata
     6241 tgcttttttg gtatctagat cttctctgac tttgactgtc gtataaataa ttttttctac
     6301 tgggatacta taataacttc cttcaccatt attgaatcgg tgaacgtctt tctttgctaa
     6361 aataccattt attttattcg tcagtacacg ttgttcgaca ctgttactta caacatagta
     6421 aatcacccga atattattga tcaaatgcaa atcgatttct aacactacat gatccatgaa
     6481 aatcccactc cttctttcac tttgattata gcaagtttct cctctaattt caaaatcgat
     6541 acagatttta ccggataaat ccacaaaact gcttgcgcca tttcgcacaa agtgttattt
     6601 tgtatcatgg actttattta tcggaggcaa tagtatgatc gcgatcggtc aatttgtttt
     6661 ttatattcct ttttttatta tgataagcat tcttttctat tacataaaat ggacaaaaaa
     6721 gaagttttca gttttactgg cctctttacc tgctgtatat tttacttatc aaattttttc
     6781 ttttaggcat tgggaaacaa cgtctgtatt aataacacac atcatcgaat tgacgctttc
     6841 agtaattttt cttattattt ggatctattt tttatataag aatcagaatt gaatccctcg
     6901 catgtttaaa aagaaaacga ttaaagatgc agcaaatttc tgccgatctt taatcgtttt
     6961 ttctattctg ttataccaaa aaaatgtttg aatcggtgaa ggatcgttcc ttgttttaat
     7021 tctataaatt cttgtgcgat cgggtacttt tcttccaaat tttctttgtt cttttcgatc
     7081 aggcttttcg cttcttcata ttttttatct gcacatagtg cttttacttc ctgtaatact
     7141 tttcctgctt ccatttgcct caccctcttg ccattttatt gctttaagtt ttatttaagt
     7201 tatacgcatt attctagttt catcccaaat aacctttttt catttttact cctcgaacta
     7261 atcagttttc taaaggctga ttggttcgtc ttttttattt ttcctccatt tcattctgct
     7321 cttctgttaa tttatctaat gctttgattg atgctgcggc tcttgcataa tcatagctgt
     7381 ataattccat aaatttatca ggcagaacaa accacgctgg atgataaccg ttagctgtga
     7441 cagggaatcc tttatcttgt tggttatctc catcccatct cagagcaaca cctttttttc
     7501 ctttccactt tactaaagcg atcgagtatc ccttctttgt ttgtgtgccg tcttcaataa
     7561 ttgctaaaat ttctattttt tcttttggcg cacggacttc ttgaggacga accattttct
     7621 attcctccct tatctcatta cttcacgacc aacacactgc aaggggcatg tgatacgaca
     7681 taagaagcgg tcgatccaac taatgcttgt tgtatagcac cttttcctgt cgctcccata
     7741 acgatcaaat caatattttc ttgtccaggg atgacattgg caatcaaatt tcttggatct
     7801 ccagtttcaa ctattgcgtg gatctcagca atgccgtact ctttggcatc attgattttt
     7861 ttcagcatgg ctacttctgt tctttgtttt tcatctgcat agatttttga aaaggcatag
     7921 gcactatggg tcagctcaac tttgttgatg attgacacga taaataagtg ggcttcattg
     7981 tcctttgcta agtcaagggc ttcagcgaac gctttgatcg attgtcttga tccgtcaact
     8041 gctaccatga tgttctggta tcttttactc attggaaccg cctccttttt cttttattgt
     8101 aacatctcaa gcaaaaatac aaaaaatata cgcaatatgt aaataaaatg atgaacaaaa
     8161 gcaatttctt tcaagttatt tatacatttc ttttctcatc agaacacctg ttctaatccc
     8221 attatttctg cattatgtga aattcctcat catttttcac atcgagcgaa catcattctg
     8281 ttacaaaaaa cgtggatttg tcataaattg tcatgcttct tttacctatg aaatattttc
     8341 acgtgttaaa gtattcctcg ttgaacacaa caaataaaac tttttaacga ataaaggaga
     8401 tttttcatga catcacttaa aactttactt tttggaacaa ctttggctgc cggcgctgca
     8461 ttcttcatgg gaacgactgc tcatgcggac gaagcttata ccgttcaatc aggtgatact
     8521 ctatcaacga tttctcaaaa atacgttggt gataactcct tgatcaatgc cattgcagaa
     8581 tcaaattcaa tttctgatat taacctgatc tactcaggac aacaattaac aatcccaaca
     8641 gaaggctctg cacaagcagc tgctgaacct caagcagccg ttcaagaagc accagtccaa
     8701 gctgaacctg ttcaagctga acaacctgtt gtacaagaaa cggttcaaac ggaaacacaa
     8761 gcagcgcctg ttgctgaaac acaacctgct cctgctgtaa cagaaactgc tgctactcca
     8821 gcaagtacaa gctctgcaaa agaatggatc gcacaaaaag aatcaagcgg ttcttacaca
     8881 gcaacgaacg gacgttacat cggccgttac caattagatt cttcttactt aaatggtgac
     8941 tactctgctg caaaccaaga aagagtagca gaacaatatg ttacttcacg ttatggttct
     9001 tgggaagcgg cgaaagcatt ctgggaagca aacggttggt actaagattc attatttgaa
     9061 cgtttaaaca cattcaaaat atagtaagag gtcatgcgat ttattctttc gcatgacctc
     9121 tttttgagtt taagtttagt ctttattcct taactatcgt ttgccagtat ttcttgtatc
     9181 agaatctata aatctactat ttgaatcaat ctattaggtt ttaaactgtc ccaccttcac
     9241 acaaattttt tttgatttat ttgaatctgg ttccgttgtt taaaattttt cctatattct
     9301 tttagataat atgttatttt ctttctcatc gctccaggtg taccttctct ttataaaaaa
     9361 acaaattatg cggctaagaa gactcgaact tccacgaggt caccctcact agcgcctgaa
     9421 gctagcgcgt ctgccaattc cgccatagcc gcatcacatc ttttagttta ggattacatg
     9481 tgttttttgt caagaacata tttttgttct ttttcatttc tgtacgccct cccttatgcc
     9541 atctacacaa ataattcatc cgagcaactc catcatctat tgagggttgg tgaaaaaatc
     9601 tgttttatcc atatgatcga tttcaatgtt aaacgaacga ctctgggatt agtaactatt
     9661 ttattttttt cttcatttct tttttcctct ttttctcgat tcagctatct tctttcattt
     9721 ggatattgat tatttcttct gttgattact atccttctgg aattctagac gctgaagtaa
     9781 ttcacgtttt ctttcttcta gagatcataa gtaacgaatg aacgaacttc aaataatttt
     9841 tttattgtaa ttcatatttg tattgttcga tgattcttaa tacgatatga cacaataaat
     9901 aaaaataggc atggctattt acaacaatag tgctatagta gaaaacaaat gaataaggtt
     9961 acttaaagag gtgaatacga tgaaactgat caaactatgg gaagcagatt taaagaaagc
    10021 ttatcagcta caaactagct ttggaccaaa tgagagtgga tttatcaaca atgcttatgg
    10081 ctatacattt gctgaatttt tagattatgt aaaaaaatgc gaaaaaacgt ctttaggaat
    10141 cgatcttcct gagagttacg ttcccgcaac cgtctttatt ttagaaagtg atgaacatga
    10201 gtatgtagga atttttaatt tgcgccataa actgaacgaa acattaagaa acggcgctgg
    10261 ccatattggt tacggcatct cccctaatta tcgtaaaaaa ggatatgcca cacaaggatt
    10321 agcattagta ctacaagagg caaaaaaaat cggcattgat gaggcacttt tgtctgtaaa
    10381 taaaaaaaat cttggcagtc ttaaagcaca acaaaaaaat ggggctgcga tttatcgtga
    10441 agatgagaaa gaatactata cgaaaatcaa actgatgtaa aaaagaagga ttccaaaagg
    10501 aaagggattt gaatgtcctt tatcaataga acacatttat ttaattaact tataatatag
    10561 cagacaaaat tttataaaca aagaaacctt ttatctcttt tcttctagaa aggataaaag
    10621 gcttttttgt ttttcctatt tgcttctcat agctagtcag ccaagatttc tatcgtatcc
    10681 ccaacgcaat ccgtgcataa cggctcatct tatctgtcgt ccatgctgga taccagacta
    10741 gtttgacttc tgctttcgtt acttctggca cttcttttaa tgcgtcatgg atagattctg
    10801 ttaaaatatc tgctaatgga cagcccatag ttgttagagt catcttaatg actgtttctc
    10861 cattttcagg attgaattct atatcataaa tcaagcctaa attgacgatg tcgattccta
    10921 attcaggatc aatcaccatt tccaaggcag caagaatacg ttctttgatt agttctattt
    10981 cttgtccaga ccgttcttgg tttgcttcgc tcatcgtacg acactcctta acacgatttt
    11041 tatttatcat actctttttt tagctgcttg taaatgagaa tttagaagta agattctcgt
    11101 ttaaatttat aaaaatgttc ttattagatg taatagatta aatttattct aaaataaacc
    11161 tgattcctca ttttttttgt gaacgatttt ttatttctgg caatacgcca gttgttcgat
    11221 acattttttg ttcgttttca tttgcaaacc ggccaaatac tgaatgagtt ggtaaaatat
    11281 tgataaatgc atcgtcgtcg atttcatgaa cgatctgatc aagatcatac atttcgtagc
    11341 gggtgatgac catcatgatc atgttccctt gtttttttga atagccaccg acagacggca
    11401 gtaatgtcat tccacgtacc atccgttttg ctagttcttc tgttacctct tctggcttga
    11461 cggtaacgat cattgctgtt actttttgat gactcgtgtg gatggcatca attacttgag
    11521 tcattgcata aatggaaata atcgtataca aggcactttc ccagttaaag aagaagcctg
    11581 cgatgactac aatgatacca tttagaatca gcatgtagtt tccgactgtt tttccagttg
    11641 tttgtgaaag tacaagagag atgatatcca tcccaccagt tgtaaagccc atttttaaag
    11701 ataatcctac gccaagacct aataaaacac cgcctactag ggcattcatc aaaatattat
    11761 cagtgatctg tccgactgga agcagcatcg tcatcaccga tacacataca acattcacaa
    11821 aactaaggat cgttgctcgt tttcctactt tgagaaaccc taatacaaac acagggatat
    11881 tcaaaagaaa aataaatgtt cctgtgtcta tcttgatatg aaaccattca tataaaagcg
    11941 aggaaatgat ttgagcgatc ccattcatcc ctgcagaaaa gacattggct ggaatcaaaa
    12001 aataatttaa agcgaccgca gcggtcaatc cggttatcaa aataaccact attttcttta
    12061 atctttcatt tttatgatac gcagtcataa ttttactcac aagcacctct cccctacttt
    12121 ggtattccaa atgtaagaat aacagtttat ctattaaaat aaaatacttc gaactcaaat
    12181 gagaagaatt ttagcaaaca ggtaagaatc tgccctaatc ctatgataag atagatgtat
    12241 ggtaaatatt tatatgtata tcaggagggt tcctatggca aaagatgcta gcttcgacat
    12301 tgtatcagaa gtcaatacag aagaagtaaa aaatgcgatt cagcaaacaa caaaagaatt
    12361 gtccaatcgc tttgacttca aggattctac agtagaaatc aaattagaga acagcaatct
    12421 agttgtattg agcgatgatg atttcaaaat cgaacagatc aaagatgtat tatttggtaa
    12481 gctgatcaaa agaaatgtgc caatcaaaaa tatccatttt tccgaatcag aacacgctct
    12541 aggtggcaaa gctcgacaaa ctgccgattt ggtcaacgga atcgatcgtg aaaacgcgaa
    12601 gaaaatcact acagctatca aaaatgaaaa actgaaagta aaagcacaaa tccaagaaga
    12661 tcagattaga gtgacaggta agaaccgtga tgatctacaa gctgtgattg ctttattacg
    12721 taaacttgac ttaccaatcg agttgcaatt cactaactat cgttaatcaa aaaacgaggc
    12781 tgacgtctgt cattcctcgt ttttttgatt tactgcttct tttgataacc aaaaacgctg
    12841 tattccttct tccaattccc caacacttcg tacttctctt gctgtttgcc aatgttgtgg
    12901 gaataaacgt cgataagaaa aactagaaaa tcgttgatct gccaatacaa cgattccttg
    12961 atccgccatg ccacgaatca ctcgaccacc agcttgcaag actttgttca ttccaggaag
    13021 ctgataagcg taagcaaatc caaggtgttc cttctcatca taatatgatt tgatcagttc
    13081 ctgctcatga ttcatctgcg gcaaacctac acctacgatc atactgccga tcaatcggtc
    13141 ccctctcaaa tcgattcctt ctgaaaaaat cccgccaagt acgcaaaatc caatcaatgt
    13201 ttcagcggga tttgtttgaa attttgttaa aaatcgttcg cgttcttcct cattcatgtc
    13261 cgtttcttgg attagcacat tgctgtcggg atattgctgt ctgaatgctt ccaccgcaag
    13321 atctaaatat tgataagaag gaaagaaaac gaaataattc ccgacctttc catcagcaaa
    13381 agcatgaatc gtctctacta attttgccag actgtgttcc ctttttcgat aagtcgtctc
    13441 taggtaattt gcgatgaaaa cttgctggtt tccttctggg aaaggactcg gcagtttgta
    13501 agccagactt ttttgtcccc ccagtgtttc ctgataataa gagagtggtg aaaaactagc
    13561 agaaaaaaga atactgcttt ttcctttatc caacgactgc tcaagaaaca agcttggatc
    13621 aatacaaaac tcttttacta tcagatcgcg atacgttttt tcgactgttg tttcgtagtg
    13681 atcatcataa aattcactga ccttcaaaaa atgaagcaaa tcaaaataat aaggaagcaa
    13741 ttgttcttgt gatgggtgct caggaaattc tgccagccat tctttaattt tttcgcttaa
    13801 ttgataacct gcctttacta aagattcagc cggtgctttt tgatgatgat aatcccaatg
    13861 atcttctttt gctatttctc ggatcgaatc aaattctttt aatagtttgt tgaaacggcg
    13921 atgaagtttt ttgaattcct ttggtatagc ttccttactt cgtttcgttt tttcataaga
    13981 tagttctgcc gaatacatct ctcgggaacg attcaccaaa ttatgtgctt cgtcaatcaa
    14041 aaacagatag tcctcgtttt tttcatcttc aaaaaaacgt cttaaataaa cagttggatc
    14101 aaataaataa ttgtaatccc caatgattac gtcacaccag atactgacat ctaatgatag
    14161 ttcgaaagga caaagtgtat gctttcttgc ataagtttcg atgacttcac gagtgatctg
    14221 attctcatga ttcaaaagat cccataaacc ttcattaatc cgattgtaat aaccattggc
    14281 atatgggcac tgatctggat tacaggtcgt ctcatctaaa aagcagatct tgtctttcgc
    14341 cgtcaaagtg acacttttta cttcagctcc tgtatctttt aatgctgtca tagcatcttc
    14401 agctacttgt ctagttattg ttttagccgt tagataaaag atcttttctc cctcttcttc
    14461 ccctacagct ttcaaagcgg ggaataacgt agagattgtt tttcctgttc cggtaggtgc
    14521 ttctacaaac aatttctgtt tcgtacggat cgttttataa gcagctaccg ctagttcacg
    14581 ctgacctttc ctatactcat catgggggaa tttcaaagcc atcaaagagg cattgcgtac
    14641 agtgcgccag ttttcttgaa aaacaagcca ttctttataa tcttcagtca gctttttaaa
    14701 aaaagtttct aactgctctc ttgtctgatg ttcaaccttt ctcgtgatca cttcttctgc
    14761 cgtctggaag taagtcaatt gcagatttat ttcttgtaaa tcatgttctt gactatagat
    14821 ataggcatac acccttgctt gatgaaagaa aagttccact tgttctggtt ctaaatcttc
    14881 aaatcgtggt tcggaggttt tgatttcatc tatataataa ataccgtctc ttttgaaaat
    14941 accgtctgca cggccttcaa cgatcaggta atattcatct aattgaactg ttgtttttaa
    15001 aaagacttct ttttcatagt tttctcccgc atctttttgg agcttgcggt ggattctcgc
    15061 tccttctaat gcagtatggt tacttttttt acgattgtcg atacttccac gtcgcaaaat
    15121 aaattctact aagtgccgca cagatatttt tgactgtttg atcatttcca ccacctcttt
    15181 ctctctaaga ttacctgaaa aaacctagtt tagcaaaaag agctctcttt ccaaacataa
    15241 aaaaacaccc tgctgattag gcagggatat ag
//
LOCUS       DAFBSV010000068        15203 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.069, whole genome shotgun sequence.
ACCESSION   DAFBSV010000068 DAFBSV010000000
VERSION     DAFBSV010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15203
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.069"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..406
                     /locus_tag="LLB18_002032"
     CDS             <1..406
                     /locus_tag="LLB18_002032"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245023.1"
                     /translation="TLFYRRDFLFSIYTKYFTLSSNIKTSTKLICKLFKLDKISNIDD
                     VKSKILTRKVSEPVKLTAQDKKNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSGEK
                     VTFKINFITAISKLEYGKQKKRDNNDQYLPKK"
     gene            487..1107
                     /locus_tag="LLB18_002033"
     CDS             487..1107
                     /locus_tag="LLB18_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245024.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            1808..2092
                     /locus_tag="LLB18_002034"
     CDS             1808..2092
                     /locus_tag="LLB18_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245025.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            2095..3012
                     /locus_tag="LLB18_002035"
     CDS             2095..3012
                     /locus_tag="LLB18_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK5245026.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            3005..3787
                     /locus_tag="LLB18_002036"
     CDS             3005..3787
                     /locus_tag="LLB18_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5245027.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            3788..4468
                     /locus_tag="LLB18_002037"
     CDS             3788..4468
                     /locus_tag="LLB18_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5245028.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            4461..5357
                     /locus_tag="LLB18_002038"
     CDS             4461..5357
                     /locus_tag="LLB18_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK5245029.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            5552..7201
                     /locus_tag="LLB18_002039"
     CDS             5552..7201
                     /locus_tag="LLB18_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBK5245030.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            7795..8730
                     /locus_tag="LLB18_002040"
     CDS             7795..8730
                     /locus_tag="LLB18_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5245031.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            8723..9493
                     /locus_tag="LLB18_002041"
     CDS             8723..9493
                     /locus_tag="LLB18_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5245032.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            9909..10892
                     /locus_tag="LLB18_002042"
     CDS             9909..10892
                     /locus_tag="LLB18_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HBK5245033.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            11339..12373
                     /locus_tag="LLB18_002043"
     CDS             11339..12373
                     /locus_tag="LLB18_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBK5245034.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTRAGS
                     NQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKILV
                     INGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELGI
                     DQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMFA
                     KTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHMLG
                     KVVVSGPFNG"
     gene            complement(12462..12785)
                     /locus_tag="LLB18_002044"
     CDS             complement(12462..12785)
                     /locus_tag="LLB18_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBK5245035.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(12772..13479)
                     /locus_tag="LLB18_002045"
     CDS             complement(12772..13479)
                     /locus_tag="LLB18_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBK5245036.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            13565..13906
                     /locus_tag="LLB18_002046"
     CDS             13565..13906
                     /locus_tag="LLB18_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HBK5245037.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SVEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAVEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            complement(14077..14925)
                     /locus_tag="LLB18_002047"
     CDS             complement(14077..14925)
                     /locus_tag="LLB18_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245038.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
BASE COUNT         4872 a         2593 c         3205 g         4533 t
ORIGIN      
        1 aactctattc tacagaaggg acttcctttt ttctatttac acaaaatatt ttacactctc
       61 gtcaaatata aaaactagta cgaaattaat ttgtaaatta tttaagcttg ataaaataag
      121 caatatcgat gatgtaaagt ccaagatatt aacaagaaaa gtaagcgaac cagtaaagct
      181 aacggcacaa gataaaaaaa atggaattgt tctttatggt gatgatgcaa agtataacta
      241 taattgggat acctcctcag aagctgaggt attaagtatt cctactaccg atacttcagg
      301 ggaaaaagtc acctttaaaa taaattttat aacggcaatt tctaagttgg agtatgggaa
      361 gcaaaaaaag agagataaca atgatcaata tctacctaaa aaataacgaa ttaatgatgc
      421 atatgttaaa gttgtttttt tgaattaaac aactcaattt attcagttat atgttcatcg
      481 cagcaagtga acattaatcg agttataaaa ttaataggag ctaaaaatat aaataaagtt
      541 cgatcagaat ttatttttcc agaagatttt tttaactggt ttttttatca attcagtgaa
      601 tgcaagcgac tcttaggtga gaattattac ttaaaaggaa tcggcggatt tatggggaat
      661 gtggctgatg aacaaaatat tataaaagga atatctgaac aaacatcaga gcttacagta
      721 actaaagcat ttataagtaa tggtgaaagt ttgaaaaatg taactgcgcg aattagaaaa
      781 gaaaatgaag tagacattgt ttttggaatt gaccatgaat gtaattcagt gatatatgta
      841 acacaatcag caaatttaat tctttttgag aatggttgca aggacgattt tatggtggtc
      901 tatttgtacg atatactaat tccaaaactt cgttccttat atatgtcttc tgaaagtatt
      961 tttgtgagtg aacaaaaggg atctttctcg aaaaaaatag gtattgaagt aattgaatcg
     1021 attatgtgtc ataatcatat tacgctagaa gaattagaaa ttttgatagg gcaaaaaaat
     1081 aataacacga aaatacaagt ttcttagaaa tcatttttta ttgagatatc tagataaatg
     1141 atttattctt caatcaacca actcgccaag ctgaggtaat gttttgaggt aatgataaca
     1201 tacaactttt tataccctag taaaactcta taaacaaaga cttattaatt tcgcatgaaa
     1261 tacattcctg taaaatgcaa taaaatagag ttttgtttaa ccaggtctta agaaagcccg
     1321 taaagcttca cagttctcaa aacgttaatt gcgattatcg ttcgagttca cgagttacga
     1381 gaatcgtact gggcgaagca atgctgagcg cagttacctt aatcctaact tttctggcac
     1441 tttccacaat ttggaaagtg ccttttttgt gtttttagct atgttaatag gtaggattct
     1501 tggtctataa tatcattcga tctataaaca aacgggaaaa agataaagta tcatcaaaca
     1561 atattattta tccgcttctg aggttgtgac agaagtggtc agcttcaaga aataagaagg
     1621 aatttacaaa aattgcttct catgtttgat aaatattgtg acttgtgacc gaggagttgg
     1681 caggagaaca ccgtttattc ggaagaaggg attgtgaaaa gtcttttgtc ataacctctt
     1741 atttggtagc taattgtaaa tcccaaacgg catgtattat ttttcataag tccgttttta
     1801 aggattaatg ttttcttttg ctttttatat ggtctggctt cagcgagaag ttccaacgca
     1861 tatacaagga cgtctgatgt caacgataac aacgattacc atggtggcca gtccacttgg
     1921 attagcactg tttggtgcgc tctttgattg gcagacaact caaccacgtc tgcgagacag
     1981 tctgattttt cttgaaattc aattggaaaa tttacacttt ctttatacat ttctggctgc
     2041 tttctttata cccgtcaact atacttcact tatcaataag aaagaaggat aagtatggat
     2101 tttggaaatg aaacggtctt gaaagcaact ggtataacca aaaaatacgg tgctgccaaa
     2161 gcattagata aagtatcgat cgaaatcaaa cgtggaatga tctatggttt gattggggag
     2221 aatggagcgg gtaagtctac ctttatgaga actattatgg gtttgatctc gattgatgaa
     2281 ggttcgatcg aattatttgg aacgacggat ttgcaggcag caagacgacg tatgggtcaa
     2341 tcgattgaaa cccctgctct ttatccagaa ttaactgcaa gagataacct acgtatccaa
     2401 gcagcgaacg gcggtgtgtc ggatagagaa atcgaagacc tgctgaaaat gatgcgattg
     2461 gaaaatacag ggaaaaagaa agcaaagaat ttctctttag gtatgcgcca gcgtttagct
     2521 attgcaaatg cactgatcac gaatccagaa tttttgattt tggatgaacc gacgaatggg
     2581 atggatccag cagggatggc agaaatgcga gaaatcatcc aacgtttggt aaaagaacgg
     2641 ggcatcaccg tcttgctttc tagccacttg ctagatgaat tgtcacagat cgccactcac
     2701 tacggtattt tgcatgaagg acacttgatc aaagaattat cgaaagaaga attggcacaa
     2761 gaatctcgtc aatttataaa aattgacact tcggcgacgg aacaagcagt aacggttctc
     2821 gactctcttg gttataggga ttattttgtc caatctagcc gtgttatcca gctttttgaa
     2881 ggaattgacc aagtagcagc catcaatcaa gcattggtag aggcaaaagt tcctgtggat
     2941 ggtatccacc tagttgggca aaaactggaa gattatttct tacaattaac tggaggcaat
     3001 ccacatgttt aatctattaa ctgctgaaaa aataaaagta tggaagagcc gtaaaatgtg
     3061 ggtctcacta ggactgatgg tcgtacttcc gcttttttat tcttggaacg aatggtatat
     3121 gcatacaaaa tacggcaatg aattaaacca agcaacggat acagtcatca acggtgcaac
     3181 agggatttta atggtggaaa aaatggctgc atggattctt ctggctttcg cagcatttgc
     3241 gtgcttttat attggggaag aatttcaaaa cggtacgatt cgcaatacgt tatctttagg
     3301 acggaatcga atgacttatt atgtgtcgaa acttctcgtt acgcttttga tcacaacact
     3361 tggcgtggtt ttgattacgg ggctagccat gattgcttac acacttgctt tcggatttgg
     3421 tgaagttgag ggaatcaaaa actatggaaa ttatgttcta aaagtatttc ctgtattgct
     3481 tctgctgata ttagcgacat tatctgttcc agtggctttg acattcatca ctagaagtac
     3541 cagtgtcagt ttgcttcttt cttttcttta tatcatggga acggccttcg ttcccggtgt
     3601 tttcgcaaaa atcaaaggct tggaatttct aacggagtgg tttacggaaa cgtggctcat
     3661 gtatacggac tttgcgcaac aagcaactta ttcgcaagca ccgaaaatga ttctggtcag
     3721 tctagtaaca atcgtggtat catcagctct aggaatgttt attttccaaa aatctgacat
     3781 taagtaggtg ttcctgctgg aaactatttt gattatcgaa gacgatgaag ctgttcattc
     3841 tttactggag gaggttcttg aacagagata caaacttctt gatgcttatt caggtacgga
     3901 aggaaaatta ttgttaagca catatcctgt cgatttgatc cttctagatc tcatgcttcc
     3961 agggctttca ggtgaagcat tgttagcaga aatccgacag acatcgaatg ttccgatcat
     4021 cgttctttca gcaaaaagcg atcaaagaga taaagtttcc ttgttggcag caggagcgga
     4081 tgactatgtg acgaaaccat ttgatatcga agaactgttg ttacgaatcg gcatccaact
     4141 tcgtcatcag acttctgtcc aagtaaaaga tctgtcgcaa cgcatctatt acaaggaaat
     4201 cttactggac aaagagtcga gggatgtaaa tgtgaatggt gtggctgtcc atttgacagg
     4261 aagagaattc gatctgctga agcttttttt agaacatccg aaaaaagtat tttcgcgagc
     4321 aaatctttat gaaacagttt ggcaagaacc atattttgat agtgagaaaa cagtgaatat
     4381 gcatatttcc aatcttcgag ggaaactagc aaaggcacat gctgtgtata ttcatacggt
     4441 gtggggagtg gggtttagat ttgattaagt ggctgttgct tctcgttgtt atctttatgg
     4501 gaagttttat tttcttcctg caaagggaaa tcaagagatt aactaagaaa atcgccactc
     4561 tttctgaacg acaagaatat ggtggtcgtc tttcagtcga atttcgagaa aagaatctaa
     4621 tggacctagt agatgcactg aatacatggg tggatgaaaa tgaacaaaaa ggacaagcat
     4681 ttcaagaaat ggaagaaaac atcagactat cgatcgtcgg cctttctcat gatctcagaa
     4741 ctcctttgac tgctattaac ggttatgtac aattactgga acaggtagag gatacggaga
     4801 aacgggagaa gtatttaacg atcatcaaac aatctgttgc aagattactc agtatgacgg
     4861 atcagtttta tgatcttgct cgaatagaga cgaagcaaaa agaaatggat ctccatacgc
     4921 tttctttttc taaagaggtg gaagaagtat ttttctcttt ttatgaacaa ttttctgaga
     4981 aaaatatcga ggtagcgttc gctgaacact cgataaatac aactgtatta gcagatccgc
     5041 tcatgttgct gcgagtgctg caaaatatca tacagaattt attgcgttat gcagatggac
     5101 aagcaaaggt gacattttca aaagaggatt cattcattcg attaacagtg gccaatccta
     5161 tcaaaccagg agcgcaaacc tctgttgaaa aagtcttcca gcgtttttat accgaaaata
     5221 ccagccgcac aaatacggaa tctagcggaa tcgggcttta cctgtcaaaa aaattggtgg
     5281 aaggaatggg aggagagatg accgctagat tagacggggg catcttctcc atctccgtca
     5341 agttgcggag ggtttaattg gctctaattt acctgaagtg aatgacaaaa aattgtatct
     5401 cgttttaaag acatcttctt ttttggaagg tgtttttatt ttggtgtgat tgatacgaat
     5461 taggtaacga agacagttat ttttgtaccc ccttttcaaa tagcgcaaca gtgctatact
     5521 aaaactaaca aatcaaggaa cggagaggga tatgggccaa agagaattta tcgttttaat
     5581 tattattgca gttgttattt tattagttgt tttagacatt ttttcacgtt tgaaagtaaa
     5641 ggaaacagtt cgtagtaatt ggggaaaaat tccttatcaa ccgagatttg ataaagaaga
     5701 aagtttgaag gatgcgtggc tcacggagaa aaaattccgt tcatgggata gtgaaatcga
     5761 cgatcttact tggtatgact tggatatgtt cgaagtattt gaagggatca acagtaccta
     5821 ttctagtgta ggttcagaag cgttgtatca gcgtttacgt agctttgatt ttggagaaga
     5881 ttatcagtta gaaaaactaa ttgcttttta tcaggaaaat cctcaactga gagaaagaat
     5941 ccaatatcaa ttcgctcgtt taggaaaaaa agatcataat tttgcaaaac aatatctagc
     6001 ggatggaaaa agtaaaaaga ttggacgcgt aggtttattt atttttcttg gcttgcttcc
     6061 gctggtgggt gtaggtttgc ttcttttagg gcaagtacta ggaatctatc tagcaatcgg
     6121 tggcttagta ttcaatacgg tctattatct agtgaagaaa caaacactag aaacagagct
     6181 gaatagcatg agttatttgg tttcaacgat ttcagccgcc aatcagttag caaaaatgac
     6241 gacaccactt caaaaagagc tgaaacagca aactaaacca ttaagagaca tccctaaatt
     6301 aggtttttca tttcgaatga agagcgggag tgaagcagaa ttgatttttg aatatgtcaa
     6361 catcatgttc atgctgccat ttatctccta tcatttcgtt ctcactaaat tagaaaagca
     6421 ttcaactgaa gccatcaagc tgtgggaatt gctgggagaa ttggaagttg cagcagccgt
     6481 tttgaattat cgcacctata tgccgatcac ttgccgacca gagtttactg agggcggtgt
     6541 gacagcgaaa gatatctatc atccattgtt aaaagaagcg gtagttaatc cagtcaactg
     6601 gcagaagaat acattagtca cgggttccaa tgcatcagga aaatctacgt atgtcaaaag
     6661 tatagccatc agctgtattc tagcacagac gatccaaaca gcgattgcag aacagtttac
     6721 cctgcaacct ggacatgtgt tgacttccat ggcaatcgaa gatgatttat ttgaaggcga
     6781 cagttatttt gtttcagaaa tcaaatcgat caaacgtttg ctggaccaag tggcttccaa
     6841 agaacgctgc tactgcttcg tagatgagat tttaaaagga acaaatacga tcgaacggat
     6901 tgcttcttcc gcttcagtcg ttcggtggct tgcggagtat ccatctttag catttgtcgc
     6961 cacacatgat atcgaattga cagagatttt aaagaattat tgtgagaatg tccactttga
     7021 agaacaagta acagaaggaa aaggaatcag ttttgatttc aaattaaaag aaggaccttc
     7081 aaggacccga aatgcgattg ccttgctgaa agttttgaat tatcctaaat ccatagttga
     7141 acaggcccaa aaagaaagtt tgttgttcga tgaacagcgt cagtggtatc cgtttgatta
     7201 actttatcaa acgaagcatg atgcgtgggt ccaaaaagac gattatcaaa agaagtacat
     7261 tgatgccaaa aaagtggcag aattcaatgg gaacgagtct gctgtccaga tgatcttgga
     7321 agatttagca aaagacgata caaaataaac cacgctgtct tccttctagc agcttttatc
     7381 gaaaaaactt agcatcagcg acgagacgca cgttccatgg caaagttctc cgtaaaacaa
     7441 acagcgaaaa cagaaattga aaataactat ttccatttta tttatttcgg ttaaaataaa
     7501 agaaaaaagc tttcgataaa aggacggagg aaagcttaac atgaataaaa aagacaagaa
     7561 cctcagttat aaggatcttc tatatgtcat cgtagtagtt gctgtcggta cttttatgat
     7621 tttaaaagtt ccagagttgt ttagatagtt attctatcga agatgatcat gaactagaaa
     7681 acacatctcc tctttgttag caggtgtgtt tttgtgtgga agccaagttg ttttttcatc
     7741 tgctgtattc catgatacaa ttaagaatca tgtctataag gagataggaa ataaatggca
     7801 aatgcgcttg aaataaataa tttgaaaaag atctatggaa gtggggtcga agcattgcgg
     7861 ggaatcgatc tttcggtgaa agaaggagat ttctatgcgc tattagggcc aaatggagct
     7921 gggaagtcta caacgatcgg gattattact tctttagtca ataaaacatc tggaaaagtg
     7981 aatgtcttcg gttatgatct ggacaaggat ctagttcgag caaagcaaca gattggattg
     8041 gttccacaag agttcaattt taaccctttt gaaacggtcc agcaaatcgt cgtgaatcaa
     8101 gcaggctact acggtgtctc tcgcaaagaa gcgatgaaac gcagcgaaaa atatttgaag
     8161 cagtccaatc tttgggaaaa gagaaatgtc cgtgcacgta tgctttccgg gggaatgaag
     8221 cgaagactga tgattgctag ggcattgatg catgaaccac gtttgctgat cttggatgaa
     8281 ccaacagcag gagttgacat cgagttgaga cgcgagatgt gggagtttct acgagaattg
     8341 aacgaaaatg gtacaacgat cattttgacg acgcattatc tagaagaagc tgaaatgctt
     8401 tgtcgcaaca tcggaatcat ccaatcgggt gaactgatcg agaatacaag tatgaaagag
     8461 cttctgtcaa aactgcaatt tgaaacattt atctttgatt tagcgccata tgataccaaa
     8521 cctgtgattg aaggatatgc ttgtacattt gaagatgagc agacaatcgc tgtcgaagtt
     8581 gaacgaaatc aaggggtgaa cggaatcttc gatcagctta caagacaagg aatcaaagtt
     8641 ctttctatga ggaataagtc gaatcgttta gaagaactgt tcttgaaaat cacagaagaa
     8701 aataatcata cggaggagaa aaatgtttaa tctttatttt actgcattaa aaagtttagc
     8761 tatcaaggaa acgaaccgct atttgcgtat atgggtccaa acactggttc cgccagtgat
     8821 cacgacatcc ttgtattttg ttattttcgg aaaaatgatc ggtgggcgga tcggtgacat
     8881 gggtggtttt tcatatatgg aattcatcgt tcctggtttg attatgatgt ctgctatcac
     8941 tagttcgtat gccaatgttt cttcgtcctt cttctctcaa aaatttcaga aaaatatcga
     9001 agaaatcttg gtagcacctg ttcctacgca tgtgattatt tggggctttg tgattggtgg
     9061 tgtgggtcgc agtattctcg tcggctctct cgtaacgatc atttccttgt tctttgtacc
     9121 acttcatgtg tattcatggt tcatggtcat cattacatta ttgatgacgg caatcttgtt
     9181 ttcattagca ggactgctca acgggatttt tgctcagtct tatgatgatg tatcgatcgt
     9241 gcctacattt gtcttgcagc cgttaactta tctaggtggc gttttctatg ccatctctat
     9301 gttaccgccc ttttggcaag ctgtttcaaa agtcaatccg atcgtttata tgatctccgg
     9361 tttccgttac ggattccttg gaacgatcga tgtgccagta gcaacatcga tgatcgtact
     9421 tgtgttattc atcgttgttt tgtacgccgt tacttggtat ttgatcaata aaggaagagg
     9481 attgagaagt tagaaaagag gttgtgaaat cagcgttttg acctgagtat tagagaaaca
     9541 aacgggaaaa tagttcctca tattttgttg ttttttgagc gaataccgag ggtcagctga
     9601 ttgaacaccg tttagtggag aggttgtgaa aaagctgttc tgcatcaagt aataagaaca
     9661 gccaaacaaa aatagctcct cctatttttc gtttggttgg acttattacc gcagatgcaa
     9721 gcttttgaac accatttatt ccggaaaatg gactgtgata agatttttgt cacagtcttt
     9781 tttttgctca atcagaaaca tcttttaagc tgttcacttt gcttcttttt ttgtttccta
     9841 gtataatgac aatgtttttg agaaagattg cgacttcact gcttgataga atggagagta
     9901 acaaataaat gactactaat ttttggaaag agctgccaaa gccttttttt gttttagcac
     9961 caatggaaga tgtaacagat gttgtatttc gccatgtcgt aaagcatgca gcagcaccgg
    10021 atgtcttctt tactgagttt acaaactcag acagtttctg tcatccagat ggaaaagaca
    10081 gtgtacgagg aagattaaca tttacagaag atgaacagcc gatggttgcc catatttggg
    10141 gagacaagcc agaatttttt agagaaatga gcattgctat ggcagaaatg ggcttccaag
    10201 gaatcgatat caacatgggc tgcccagtcc ctaatgtagc agaacgtgga aaaggcagtg
    10261 gcttgatcct tcgtccagaa gtagcggcac aattgattga agcagctaaa gctggcggtt
    10321 tgcctgtcag cgtcaagacg cgtatcggct atacggaaat gtctgagatg gaagaatgga
    10381 tcagtcacct acttcatcaa gatatagcca atctttctgt ccatttgcgt acgcgtaaag
    10441 agatgagtaa agtagatgca cattgggaag tcattcctaa aatcattgct ttacgtgacc
    10501 aaatcgctcc acaaacacta atcacgatca atggagatat ccccgatcgc cagacaggag
    10561 aagaattggc cgagaaatat ggcgttgatg gcatcatgat tggccgaggg attttcaaga
    10621 atccttatgc atttgaaaaa gacccgaggg aacatacaga aaaagaactg atcggactac
    10681 ttcgtctgca actagatctg caagatcatt attcagaaat catcccgcgt tccatcacag
    10741 gactacatcg tttctttaaa atctatatca aaggatttcc aggagcaaat gacttgcgag
    10801 ttcagttgat gaatacgaaa tctactgatg aagtacgaga gatcttagag acctttgaaa
    10861 aagaacatcc aacgcttttc agtgaacaat gatttcttgc ttgaacaccg tgaattagag
    10921 gtcgtgaaaa agctgtcctg tatcaagtaa taagaacagc caaacaaaaa tagctcttca
    10981 tattttgtcg ttttttgagc taataccgag ggtcagttga ttgaacaccg tttatatcag
    11041 aggttgtgag cctgccgttt aactctgagt cacaaggagc aatttcaaaa aacagcttct
    11101 catgtttgat gaatattttg acttgtgacc gaagagttgg taggagaaca ccgtttataa
    11161 gaggttgtga caaaagtctt gtcgcaacct cttttttaac caaaaaagtg caaatagttt
    11221 actttaagta agagaataat tatgatgaat aaaaaaggtg gaacaaatag catactatat
    11281 atattgaaat gaacactgta tggatgctcc aacttgatga agctaaggag gaattcgtat
    11341 gtcagaaaag gaattaatga aggtagtcgg tttttatgaa gggttgccga tcgatgatcc
    11401 aaaaagcttt attgatgaaa aagaacagat acctgtaccc agttcacggg atcttctggt
    11461 aaaagtcaac gcagtatctg ttaatcctgt cgatacgaaa cttcgccaag ataacgggat
    11521 aagaaatgct ttacgtatct taggttttga tggagtcggg aaagttgttg ctgtaggtga
    11581 cgaagtgcaa aaattttctg tcggcgatcg cgttttttac gcaggtacaa caagagcagg
    11641 aagcaatcaa gaataccaac tagttgacga acgtattgtc gctcttgcac caaaaaatct
    11701 ttcagatgaa gaagctgcag ccttgccgtt gacctcattg accgcttatg aattgttatt
    11761 tgaaaaattt ggtctaactc cagaagaaaa tgccaatcgc gggaaaaaaa tcttagtgat
    11821 caacggatcc gggggcgtcg gttcgatttt gaatcaacta gcgcattggg ctggcctaga
    11881 agtctacgcg actgcaagtc cgaagaattt tgaatggctg aaaaaaacag gtgtagacta
    11941 tccaatcgat tatcatcacg acttaagtaa aagttttcgt gaattaggaa tcgatcaagt
    12001 agagtatgtc gctgtattat tcgatattac ccgctacttt gatcaaatca agcaccttgt
    12061 ccgaccattt ggacatgtgg gaacgatcgt agggatcaaa gagccgttag atataggtgt
    12121 ttggaaaaac caatctatca gcttcgactg ggagtatatg ttcgctaaaa cagactataa
    12181 ctatgaaatc gaaacgcaag gagaagcttt agcgcacatt gctgctttag caaatgaagg
    12241 gattatccgc agtacattga gcaaggtcta ttcagatggg atgaatgcga agaacttgaa
    12301 acaagcaacc aaagacgtag aaacaggaca tatgttagga aaagtcgttg ttagtggtcc
    12361 gttcaacgga taagcaagaa tacgccgatt tttttcttat ttgactttga taaaaacaag
    12421 agcgcatgac agtaatttgc cataagctct tgttttttta tttataataa gcgaatcaac
    12481 gaaagggaaa gaattcctgc caagacgatc accaataagc tttttgaaag aatagcagct
    12541 aaaagtgtag gaactgaagc caaagcattt tcgagattga tctgcggcag atgtccgata
    12601 ttttgggtaa atagactgct gaaccataaa gcagacataa tgacgatcgg gacaaaactt
    12661 aaatactcaa gcaacggttg cggtaaatcg aattttttca gtaagacaaa tggtaggacc
    12721 ctagaaagcc aagttgctaa agtacaacct aaaatagtca gcaatgtaaa ctcaaaagaa
    12781 ggcatgtttg atccacaccc ccaatccgca cccaatcagt gttacaacta caatcactaa
    12841 gttgcttggg ataaaaatca gtccgacata taccagaatc aaagtgagac caatcaggat
    12901 caactgtaat cgtttagagg tgtttctatc agaaatgact tgaagataaa gtaacccgat
    12961 aaacatagcg acgatggcga aatccaaacc aaactttttc ggatcagtaa taaaattccc
    13021 taaaagtgcg ccaacaagag aagaacccac ccacgtcaaa taagaaatcc aattagctgt
    13081 attcatccaa cgaaagttta acttttgtcc agtatagttc aatttattca ttcccagtgc
    13141 gaaactttca tctgtcagca atgtgccaat cagcagattt tgaagcagcc gatttttctt
    13201 gaaataagga gcaatcgtca tactcatcag aatcattcgg gaattgacta gaaaggtcga
    13261 gaaaacgatg gaaagcaatg ggctgtgact agcaagcatg ctgactgtga taaattgggc
    13321 agaaccagca tagaccagca gggacatcaa cgtgacgact agtggatgaa atccggcagc
    13381 tttcccaacg ataccaaatg caagtccaat accgatataa ccgaaaacgg taggtaacgt
    13441 gtctttgatc gcagttttta tatctaactt ttcatccaat aacaaaactc ctttagcacg
    13501 acataaattt tcataattgt cgttaaactt gtgaatattc taaattttta atgagcattt
    13561 gtcaatggtg ggattgaaac gtaaagaact agcgggtcgc agatttacac gtattgtttc
    13621 ggtgggagga ggcgcgaaaa atcttgcatg gctacaaatc caagctgata ttttcgatgc
    13681 aacggtctat tgtttaagtg tggaggaagg acctgcatta ggcgcaacaa tgattgctgc
    13741 actagggtta gggtggttcg acacacctga aagttgttgt cagaatttta tccaatatac
    13801 agatgcagtg gaacctctct tacaaaatgt agaaaagtat cataaaatct atcaacaatg
    13861 ccggaaaatc tatccagcaa cgaaggaaat ttgtcatgac ttataaaaca aaacgcgtac
    13921 ctaatagtca aatgactaat attgggtacg cgttaagtct tctttacttc atcctttgca
    13981 tgattcgtgt ttttaaagca aggtctgctg tatttcttgt ggatttagga tggttgttat
    14041 cgtttacttg ctatttttca ttgaaatcgt ctttctttac cgtttcttta gttttttatc
    14101 tatttttttc ttttggttag aaaattcttt ttcccgaaag tcttctttca ggatttttat
    14161 agagtagcgt tttgaataag aggcgtcagt atgatcgact tggcagacga accaagagaa
    14221 catttgcctt ttttctgcat gaggtgcttc tgctaataat tctttccata aataataaca
    14281 gtcctctatc agaagaaggg ttcgttcatc ctcaggctcc caatagaatg tttcgagagt
    14341 agcaatcact tcattgatca attcgaatgc gggaagatag gcattttgct gaataagcga
    14401 ttcaactgct tcttggatga actttcgcat ctccatgatg aacttcgctg ttttcctgtt
    14461 tttgtttttc ttgataatat gatcgtattt atggatgata gttgttaatt tatctgaata
    14521 atttattgca tgaaatggca tcttaacttt gaagcgttcg ataaagtgcg gatgttctat
    14581 aagaatctct gttaaaagct cccgtacaag agaggaacta gcggaggaaa caagggacga
    14641 gagttcggaa agtgagtagt tggatttttt tattggacgt tcttcgtaag cgaataagac
    14701 agcagccatg tgtttgcatt tttttccttc tatggcatat agacaatcac aagtcatgtt
    14761 ggtcttttca tcccaagtga tcactacctt ataatcttcc gtgccagaaa ctgttgcgga
    14821 caagtacttg cttgtatagt tcaaatgacg gacaaaaccg tgcagatgat agctgtaacc
    14881 gcgttccaaa acgttttcag gaaaatactc aagccaatta ttcatctagt tctcctttca
    14941 tgaaacactt atttatattt agtataaaga aacgtttaag aaaaaagtag ctgattttac
    15001 atatttgata atcacttttg ctcgaattgt caaaaattca ttctcctttt cttttcttag
    15061 agaatgtgag aaaaagtaaa agaatagcgt gttttaaaga tggaactttt tttgtttttt
    15121 atttatctga caaaaatgaa gtgattttgt tagaaataaa taattgttcc aattgataaa
    15181 agaggtatga tgtatcgcaa aga
//
LOCUS       DAFBSV010000069        15075 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.070, whole genome shotgun sequence.
ACCESSION   DAFBSV010000069 DAFBSV010000000
VERSION     DAFBSV010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15075
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.070"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            182..1039
                     /locus_tag="LLB18_002048"
     CDS             182..1039
                     /locus_tag="LLB18_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HBK5245039.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            1154..2074
                     /gene="pstC"
                     /locus_tag="LLB18_002049"
     CDS             1154..2074
                     /gene="pstC"
                     /locus_tag="LLB18_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBK5245040.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            2074..2958
                     /gene="pstA"
                     /locus_tag="LLB18_002050"
     CDS             2074..2958
                     /gene="pstA"
                     /locus_tag="LLB18_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBK5245041.1"
                     /translation="MNAKRSDKIATGVLYVVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            2973..3779
                     /gene="pstB"
                     /locus_tag="LLB18_002051"
     CDS             2973..3779
                     /gene="pstB"
                     /locus_tag="LLB18_002051"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBK5245042.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3795..4553
                     /locus_tag="LLB18_002052"
     CDS             3795..4553
                     /locus_tag="LLB18_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBK5245043.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4566..5243
                     /gene="phoU"
                     /locus_tag="LLB18_002053"
     CDS             4566..5243
                     /gene="phoU"
                     /locus_tag="LLB18_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBK5245044.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5480..6511
                     /locus_tag="LLB18_002054"
     CDS             5480..6511
                     /locus_tag="LLB18_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBK5245045.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTNQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKHGLFALGSLIINIVLLLLLLLIFTKIEGISLLNISILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNLWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            6508..7275
                     /locus_tag="LLB18_002055"
     CDS             6508..7275
                     /locus_tag="LLB18_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBK5245046.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTTIELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            7375..8943
                     /gene="liaX"
                     /locus_tag="LLB18_002056"
     CDS             7375..8943
                     /gene="liaX"
                     /locus_tag="LLB18_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HBK5245047.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            9240..9560
                     /locus_tag="LLB18_002057"
     CDS             9240..9560
                     /locus_tag="LLB18_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HBK5245048.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            9560..9910
                     /locus_tag="LLB18_002058"
     CDS             9560..9910
                     /locus_tag="LLB18_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBK5245049.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            10077..11015
                     /locus_tag="LLB18_002059"
     CDS             10077..11015
                     /locus_tag="LLB18_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBK5245050.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            11030..11860
                     /locus_tag="LLB18_002060"
     CDS             11030..11860
                     /locus_tag="LLB18_002060"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBK5245051.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            11904..12929
                     /locus_tag="LLB18_002061"
     CDS             11904..12929
                     /locus_tag="LLB18_002061"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBK5245052.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHCLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPVEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            12944..13882
                     /gene="galU"
                     /locus_tag="LLB18_002062"
     CDS             12944..13882
                     /gene="galU"
                     /locus_tag="LLB18_002062"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBK5245053.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            14007..14447
                     /locus_tag="LLB18_002063"
     CDS             14007..14447
                     /locus_tag="LLB18_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBK5245054.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            14450..15052
                     /locus_tag="LLB18_002064"
     CDS             14450..15052
                     /locus_tag="LLB18_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBK5245055.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIIIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
BASE COUNT         4966 a         2565 c         3260 g         4284 t
ORIGIN      
        1 aagctaatat atgctattaa aagagacaca tttcaaagcc agtatagcat agaaactttt
       61 aatgagatag ttttttttac aattatgagg atttattttg ttatttaatg attttgattc
      121 gttttcatca agtaatgaaa atgataaaat aaacatactt taggattaaa ggagatttct
      181 aatgaaaaaa cttaaattat tcttaccaat aataggatta gctattcttt tatcaggctg
      241 ttcaaagtgg attgatcgag gagaatccat tacggctgtt ggctcttctg ctttacagcc
      301 tttagtagaa acagttgctg aaacttacca gacagaaaat cctggaaaat tcatcaatgt
      361 acaagggggc ggaagcggaa ctggtttgtc tcaagtacag tcaggagcag tcgacatcgg
      421 aaactctgat ttgtttgcgg aagaaaaatc ggggatcgat gcctcagcat tagtcgatca
      481 tcgagtagca gttgttggga tcactcctat tgtgaacaag gatattggcg taaaagacat
      541 cagtatggaa aacctgaaaa aactatttac aggcgagatc aaaaactgga gtgaagtcgg
      601 tggaaaagat cagccagtag ttatattgaa ccgtgcttca ggaagcggaa cccgtagcac
      661 gtttgaaaaa tgggtattgg acggagaaac agctgttcag gcacaagaac aagattcaag
      721 cggaatggtg cgccagatcg ttgccgacac acccggtgca atcagctatg ttgctttttc
      781 ttatgtttcc gatgatgtag atacgttgaa tgttaacggt gtagaaccga cagatgaaaa
      841 tgtgacaacg aacaaatgga cgatttgggc atatgagcat atgtacacaa gagatcatcc
      901 aaaaaaactg acaaaagaat ttttagacta tatcttatct gatgaagtac aagataacat
      961 cgttggagaa ctaggttata tccctgtttc tcatatgaaa gtcgaacgtg attggcaagg
     1021 aaatatcgtt aaagagtaat ctttacacaa aatttacaaa cttagctaaa cttttacatg
     1081 ttattaaaac caaattgatg ttcaatttgt acactgagtg agtatgttaa acctgattaa
     1141 gggggagtca tctgtggaag atgtgaaaaa agtattatta acaaaatcaa aacgttcaaa
     1201 aatggaacag cgtggaaaat tcatcagttt tttatgtatc gcgctgatcg tgttggttgt
     1261 attatctatt ttttattttg tagctagtaa aggattggcc acctttttta ctgataagat
     1321 caatgtattt gattttctgt ttggtacaga ttggaatcca agccaaatcg gagcaaatgg
     1381 gaaaccaatg gtaggggcat tgcctatgat cacaggttcg tttattgtga cctttttatc
     1441 tgctattgtt gccacaccat ttgccattgg tgcagcagta ttcatgacgg agatctctcc
     1501 taaaaacgga acgaagatct tacagccggt catcgagctg cttgtaggta ttccttctgt
     1561 cgtttatggt tttatcggtt tatcagttat cgtgcctttt gtcagaagta tttttggcgg
     1621 gacagggttt ggtatcttag ctggtacatt tgtgttgttc gttatgatct tgccgactgt
     1681 cacaacgatg actgttgatg cattaaaggc agtaccacgg cactatcggg aagcttcatt
     1741 agcgcttggt gccacaagat ggcaaacaat ctacaaagtc gtgctacgag cagccgtgcc
     1801 cgggatttta acagcagtcg tttttggtat ggctcgtgcg tttggtgaag ccttagctat
     1861 ccaaatggtc atcggtaatg cagcattgat gccaacagga cttactactc ctgcttctac
     1921 attgacgtcc atcttaacaa tgggaatcgg aaatacaatc atgggaacag ttgaaaataa
     1981 tgtgttatgg tcattagcgc tgatcttgct attgatgtca ttattcttta atatcgtgat
     2041 ccgtatgatt gggaagaaag gagagctgaa ataatgaacg caaaacgctc agataaaatt
     2101 gctacaggtg ttttatatgt agtttcgggg atcatcgtat tgattttagc agctttacta
     2161 ctttatatct tagttcgggg aataccgcac atttcatggt ccttcttgac cgaaccttcc
     2221 aaagcctacc aagaaggcgg tggaatcggg atccagctat ttaactcgat ttatttgctt
     2281 ttgatcacga tgatcatcag ttttcctatt tctttaggtg cgggtatcta tctttcagaa
     2341 tatgctggaa aaaactggct gacagatgtg attcgcacgt cgattgaaat cttgagctca
     2401 ttgccttctg tcgttgtcgg tttattcggt ttcttggttt tcgttattca attccagtat
     2461 ggtttctcga ttatttctgg tgcattggct ttgactgtat tcaacttgcc tcttttgact
     2521 agaacagttg aggagtcttt acaagcggtc cattacacac aacgagaagc aggattggct
     2581 ttaggtttgt cacgctggga aacagtgata aaagtggtgg ttccagaagc gacaccaggg
     2641 attttgactg gtgtgatcct aagttctgga agaatttttg gtgaagcagc tgcattgatc
     2701 tatacggctg gacaaagtgc acctgcgtta gattttacga actggaatcc attaagtgtt
     2761 tcaagcccga tcagcatttt ccgtcaagct gaaacattag ctgtccatat ttggaagatc
     2821 aatacagaag gcacgatgcc tgatggtgtt tctgtttcgg ctggcgcttc tgccgtgttg
     2881 atcattgctg ttttactgtt caacttcggc gctcgtgcga ttggcaaacg attataccga
     2941 aaaatgactt cagcctaagg agaagaagca aaatgaaaaa atataactgg aatgaaacaa
     3001 atgtcatcac catgccaaaa gagaaagaag tagcactata tacggatgat ctacatgtct
     3061 ggtatggcga caatgaagca atcaaaggag tggatctgga atttgaaaaa aataagatca
     3121 ctgcactgat tggtccttcc ggctgcggaa aatctacgta tcttcgttcg ttgaatcgaa
     3181 tgaatgatgg gatcgctaat acgaaaatca ctgggaaaat catgtatcaa ggcgtagata
     3241 ttaatgcgcc tcaagtggat gtttatgaga tgcgcaaacg gattggcatg gtttttcaac
     3301 gtcctaatcc gttcagcaag tcgatttatg acaatattac atttgctttg aaacagcacg
     3361 gcgaaaaaaa caaaaagaaa ttagatgaaa tcgttgaaac aagcttgaaa caagctgcct
     3421 tgtgggacca agtaaaagac agcttggaca aaagtgcctt ggctttatct ggcgggcaac
     3481 agcaacgttt atgtattgct cgtgcgatcg cgatgaaacc tgatatcttg ctgctagacg
     3541 agccggcaag tgctttggac cctatttcga caggaacggt tgaagaaaca cttgtaaact
     3601 tgaaagaaga ctatacgatc atcatcgtga cgcataacat gcaacaagcg gctcgtatca
     3661 gcgactatac tgcctttttc tatctaggaa aagtaatgga atatgacaaa actaacaaga
     3721 tatttaccag accaaaaatt caggcaaccg aagattatgt gtccggtcat tttggttaag
     3781 acggaggcct caacatgaca aaagaaatta tttcatctaa agatcttcat ctgtattatg
     3841 gaaagaaaga agcactaaaa gggatcgatc taagtttcaa tcaaggggaa atcactgcga
     3901 tgatcggtcc ttctggttgc gggaaatcca cttatctgcg ttctttgaac cggatgaatg
     3961 acctgattcc gaatgtaacg atcaccggga gtgttttata taaagacaaa gacatctatg
     4021 gtccaaaaac agatgttgtt gaactaagaa aagaaatcgg catggtattc cagcagccaa
     4081 acccatttcc tttttctatc tatgaaaatg tcatctatgg attgaaatta aaaggggaaa
     4141 aagataaaaa agtccttgat caagtagttg aagaaagcct gaaggcagcg tctgtttggg
     4201 atgatgtgaa agacaaattg cataaaagtg ctttatcttt atccggtggg cagcagcagc
     4261 gtgtatgtat cgcacgtgtt ttggcagtta atccggaaat catcttattg gatgaaccaa
     4321 caagtgcgct tgatcctgtt tctactggga aaatcgaaag tatgctgtta gaattaagag
     4381 agcggtatac gatgatcatc gtgacccata atatgtctca agcttcacgt atttcagata
     4441 agacggcatt ctttttagat ggtcacttga tcgaatacaa tgatacgaag aagatattca
     4501 tgaatccaga aaaacaagag acagaagatt atatttcagg tcgatttgga taaggaggaa
     4561 acggaatgct acgtacacaa tttgaagaag aattgctgaa tctccataat cagttctacg
     4621 aaatggggat gatggtgagc agcgccgtgc acaagtcagt tcgtgcatac atcaaacacg
     4681 ataaaatctt agcccaagaa gttatcgaaa acgatataaa tatcaataac atggaaacac
     4741 gcttggagaa gaaaagtttt gaaatgatcg cattgcaaca gccagttaca actgatttgc
     4801 gtatgatcat tacggtcatg aaagctagct cggatttaga acgtatggcc gatcatgcgg
     4861 tgtctgttgc taaatccacg attcgcgtaa aagggcagac gagaataccg gaaatcgaaa
     4921 aagagatctc cgatatgtcc gattatgtga aaaaaatggt ggacaacgtc ctagttgctt
     4981 atgtcaaaac agacgaaaaa gacgcacgta cgatcgccaa tatggatcaa agagtcaatg
     5041 actatttcaa tcgaatctat aatgcaacaa tcaaaaatat gcaggaaaat cctgagacag
     5101 tcatcagtgg aacagactac ttgaatgttg ccagttatct agaacggatc ggagactatg
     5161 tgacaaacat ctgtgaatgg atcgtctact tggctacagg gaaaatcact gagttaaata
     5221 cgaaccacaa tgagattttc taaactaaag cggtgattct gccgtttgtt taggaaaaga
     5281 ggttgtgaaa tcagcggttg tgaaaaagct gttctgcatc aagtaataag aacagtcaaa
     5341 caaaaatagc tcctcatatt tttcatttgg ctggacttat taccgcagat gcaagctttt
     5401 gaacactgtt tattcgggaa agggtttgtg acaaaatatg tcacaaaccc ttttcatcat
     5461 ttcatagaaa ggataaagaa tgcaaaaaaa aattagcatc atcactatat tttttatttg
     5521 tgtgcttact tcatgggtta ttcagcatca agctgcttta tatgaagtac ctgtcatcga
     5581 gatcgaaaaa gtacgaataa aagaggatca tcaattgatt acaggaagac tgatgaacac
     5641 gaatcaaaaa ggagaatcga tttatttatc ggttccttat caaaaaaatc aaatagaaac
     5701 agcaaatata aaagcgagac aaatgtatct agtccaaatg catggagatg aatggcagct
     5761 agtagcaaaa aaaaatgatg gctggctttt cttcttcaca agtatcttca ttggcgccat
     5821 gttgcttatt ggcggaaaac atggtctatt tgctttagga agtctcatca tcaatatcgt
     5881 tttactttta cttttgttgc tcatctttac taaaatagaa gggatttctc tattaaatat
     5941 atctatcctg ttcgtcgtta tagggatgat tattagcata ttggctttag atggatggaa
     6001 tagaagcagt ataatcaaaa tttcagctgc agttacgagt gtttttttag cattttttat
     6061 ttgtcttttg acaatgaatc tttggaaaga ccaaggactg cgctatgagg aactgaatta
     6121 tctgacacga ccgtatcgtt ctgtttttct ttctagcgta ctgattggaa cagctggagg
     6181 aacactcgat accgttatca cagtcattgc gacattagaa gaattgacta agcgacaacc
     6241 agaaataaca gcgaaacagt tatggctttc gggaaggcaa gtgggtcgag atgtgattgg
     6301 ctcgatgacc aatatccttt tgttcgtcta tatcagtggg tcagttccat cgcttctttt
     6361 atatttagga aatcaatggt cgttcaaaga aacgatagaa cagcatttat cattggaatt
     6421 tttacgcgtc attgctggca gcttaggaat agtattatcg atccctatct cggtcctctt
     6481 ttttctgact gtaaggaggc tgaaacgatg aatgtactta ttatacttgt tgggatttta
     6541 gcaatcagcg tgctacttat tggcggtacg caaggtatgt atattctttt aggcttattc
     6601 atcaatttag ggatcttttt cttgttgtta ttcggttatc atcagaagtg gccgatactg
     6661 gcattgtcgg tcataggatt tttattgatt gctgtggtta tcttattttt tatcaacggt
     6721 tataatctaa aaatgcgtgc agcttttgtg agtatactga tctttttatt ttgtttccta
     6781 ctattgcttc ctatcactga ttttttagca atccaaggtt ttacaacgat agaactagaa
     6841 gaattatctg gcttagataa gactttagcg attgatttta gattacttac gagatcgttg
     6901 cttctgatta gtcttagtgg tgctgtttta gatgcgagtg tagcaatttc tagtgggaca
     6961 ttcgaagtat atcaggcaaa tccgcaatta tctttttacc aattgcgcca ttctagtttc
     7021 gctattgcta aaaaaatatt ggcgtcaaca gtaatgacac ttctttttgc attcatggga
     7081 agttctttag cgttgatcct ctggtttatt gatttagaca ttccttttca gcaagtgatc
     7141 aatgaaaaat catttgttct agaatatacg atggctattc ttaccacatt gtccgcacta
     7201 cttgttcttc ctttaacctg cgtgactaca gcatatctct ttacaaaaaa gaaagaacaa
     7261 ctcaagatgg agtaaaagtt acaacttaag tcctatgaca tttttactga atcagtgcat
     7321 aatatggatg taaggaaaag cttgcaaaca attttgctta aggaggcaat ttccatgaaa
     7381 gaaagagaac gtattttaga tttagtgaaa aaaggaatcc tttcgactga agaaggctta
     7441 gatttattag aaagcatggc aactgaaaaa gacgaaaagc aaatcaaaaa agaagcagac
     7501 aaggtaactg ctagtcataa agaaaaagat caggcaagtc aattgatcga taaacttgaa
     7561 aacggcgaag aagaaatttc tgagccagtt gatccaaagg aaagagaaag acaagatcaa
     7621 gaaaacttag aaaagatctt agatgaacta gcaactgaag cgaataaaac ttcggcgcgt
     7681 ctagatgaag taaatgctca attcgctgac aataaggcag cacgcaatga gaaacaggaa
     7741 gcattgatgc agctgaatac aaaagaagaa ttaggcgagt tgacagaaga agaattagca
     7801 cagcgtcaga cgttagaagc agaaatcaaa gagttagaag ctagtggcga tacactgtta
     7861 gaagaacaat tgaaattaga agcagaatta aaagatatcc gtaagaatca atggtctgag
     7921 aaaaaagaaa cgtttactga taagtttgaa ttgccagatg attggaaaga tcaagcaaca
     7981 gatacactga atcaagtagg cgaaaaaatg tcagaagctg gatcacagtt aggaaaattc
     8041 ttgaagaaaa cattccaaac tgtttcagaa acagtgaatg acaacatgga atggaaagat
     8101 gtcagcttgc gtgtccctgg gattgcgaca acgaaatttg agcatgaatt ttactatgaa
     8161 gctcctgcag caagtatcct tgatatcaag gcagcaaacg gaaacgtgac gttaaaaacg
     8221 tgggacagca acgatgtgaa agttgaagct aagatcaaac tttacggaaa aatgggtgct
     8281 gaaccatttg aagcattctc tgaacggagc cagattgagg ttaatgaaga tcatatctcc
     8341 ttccaaattc caaataaacg tgtgcgtgca gaccttgttt tctacttacc taaacgagta
     8401 tacgaccacg cagctattaa acttctaaat ggcaacatca tgattgaaac attggaagct
     8461 aaagatattt atacaaaatc tacgaatggt aacatcatcg tggaccaatt aactgcaacg
     8521 atgctggaag tagaaggtgt aaacggcaat atcgatattc gaaacgggaa catcttagat
     8581 tctattatcg aaacagtaaa tggtacagtg acatttggtg cgacagcaga aaacctttct
     8641 gtgtctttgg taaatggtga tgtacgtctt acgattaaag aagataattt gaaaaaagta
     8701 gaagcaagtt cagtgaacgg aaatgtcaaa gtcgctttac cagatggcat cggtttggaa
     8761 ggacatgcta aaacaagtct tggaagtatc aacagccgtc tgtccaatta cgaagtagtt
     8821 cgtgagaaaa aagaacggac aaaccaaatg ttgcaattcc gtcgtgtttc agatggtgaa
     8881 atcgcgcaag tgcaactttc aacgacaaca ggaagtatct atttaaaaga tacagataaa
     8941 taaagaggtt gtgaaagaga tgttcagcct tgagcaataa gaagcgattt tgtaaaatag
     9001 cttcccctat tttacaaaat tgtgccttat tgccgatagg ctatctcttg aacaccgttt
     9061 accaagagat tatgaacttg ccaattatcg ccgagtcaca aggaataatt tcaaaaaaag
     9121 ctcgtcacgt tttatgaata tggtaatttg tgaccgagaa ttttgcaaaa agacaccgat
     9181 taagaagaag gttgtcacaa cgattttctt catttaaaat agtagaacag aggtgagaca
     9241 tgatgaaaaa aaagttgaca aaatccaata aaaatgttgt tttgacaggg actttagcag
     9301 gaataggaga atacatcggg attgatccga ctgttatccg tgtgctttat gtattcctga
     9361 gcttagttgc ttttggaagt ccaatcattt tatacatttt attagctttg attatcccat
     9421 ctgcgcgttc tgcacgaaca aactatggac ataacaatgc atattatgaa aaaaacaatt
     9481 atcgtgaaca aactcgtgaa caaacaaaaa aacgcaaaga agcggaaaaa atcgatgatg
     9541 acgaatggag tgacttttaa tgtcgtactt tcaacgtatt ttagttaata cgttaacatt
     9601 catatcattg gctgttcttt ttcctgcgat ggtccatgtg agcagtattt ggacggccgt
     9661 tcttgccagc ttcgtattgt ctgtgttgaa tatgtttgtc aaaccgattt tgacgatact
     9721 gtccctgccc tttacattag tcacattggg attgtttacg tttgttatca atgcagcgat
     9781 tcttaaaatg acctcctttt ttgtgggagc agaacatttt agtttttctt cattcggtgc
     9841 agcgttgtta gtagctatct tgatgtcgct tgtcaatgta attgtcagcg aacataacag
     9901 tagaaaataa aagaaagctg tgccgaacta tcggcgcagt ttttttattt agaatcagga
     9961 atgcgttttc tattacattg gtaattaaat aaaaacgttt tttttaattg gtagtacttt
    10021 tggctagaca atgataaaat gatagagaac actctaatag aaatgaggta gcatgaatgt
    10081 cagaagttgt aaaagttagc caattagtga aaaaattatc tttggaaatc gtgacaggcg
    10141 acgagaaaag cttagaccgt gtcatcgtaa ctggggacat ctcacgccca ggactagagt
    10201 tgactggtta ttttaattat tattcccata atcgtttaca gctatttggc agtaaagaaa
    10261 tcagttttgc ggaacggatg atcccagaag agcgtttgat catcatgaga agattatgta
    10321 gtgaagatat gcccgcattt attatttcaa gaggattacc agctccagaa gaaatgatcc
    10381 aggcagcaaa tgaaaatggg atagctgtac tgcgttctcc catctcaact tctcgcttat
    10441 taggagaatt atccagttat ttagatggtc gccttgcccc tcgaacaagt gtccacggtg
    10501 ttttagtgga tgtttacgga ttaggtgtac tgattcaagg tgacagtggg ataggaaaaa
    10561 gtgaaacagc gttggagttg atcaaacgcg gtcatcgatt gatcgcagac gatcgagtag
    10621 atgtttatca gcaagatgaa ttaacggtga tcggagaacc gcctaaaatc ctggaacatc
    10681 tgattgaaat ccgaggaatc gggatcattg atgtaatgaa tctttttggt gcgagtgcgg
    10741 tacgtggctc tatgcaagtc cagttggctg tttatctgga agcatgggca aaagataaga
    10801 aatacgaccg tctgggctct gaagacacga ccgttgaaat cgcggaagta ggcattccac
    10861 aaataaaaat ccctgtcaaa acaggacgaa acgttgcaat catcattgaa gtagccgcga
    10921 tgaatttccg tgcacgtaca atgggctttg acgcaacgaa aacatttgaa gaaagattaa
    10981 gtcgcttgat tgaagaaaac tcaggcaacg actagcaagg agtgacaata tgttagcaca
    11041 aatcaatcga gttgcttttg agcttgtagg gattcctatc tactggtatg cattgatcat
    11101 cgtatcaggt atcattatcg ccatgtggct tagcagcaga gaggctgttc gggtaggatt
    11161 aaaagcagat gatgtgacag attttatgtt gtggggattg cctatctcca ttattggcgc
    11221 tcgcttatat tatgttttat ttgatcttcc ccagtatata gctgatccaa tccaaatatt
    11281 caatatccgt tcaggaggct tagctattta tggcggactg attgcaggcg cgatcacgct
    11341 gtattttttt actaaatatc attttatttc tttgtggact tttttagata tcgctgcacc
    11401 aagtgtatta ttagcacaag caatcggtcg ttggggaaat ttcatgaacc acgaagcata
    11461 tggaccagac acgacgcgaa gcttcttaga aagtctgcat ttaccgcaat tcatcattga
    11521 taatatgtat atcgaaggga tctatcgtca accaacattt ctttatgaat cactttggag
    11581 tttgattgga tttattttgc ttttgttttt acgaaagaaa ccacaccttt tgaaaaaagg
    11641 tgaagtcctt ttatgttatc taatgtggta tagtttcggg cgtttcttta ttgaaggatt
    11701 acgtacagac agtctttact ttttaggtgt gatccgtatt tctcaattat tatctgctgt
    11761 gttatttgtc ggtacattga ttctatttat ttggcgcaga aaaaaaggaa atttaccgga
    11821 ttatgaccgc tcattaggaa aaaatcaaca aattatctga tttttagagc gttaaaaatg
    11881 aaaaaaattt caggagtggt aaaatgaatt atagagtagc ggttttagga ccaggctctt
    11941 ggggtactgc tttggcacaa gtcctcgccg aaaacggaca tgacgttcgg atttggggac
    12001 atcgtgcttc acaagtagaa gaaatcaaca cccaacacac gaatcaacgt tatttaccag
    12061 atcattgtct acccgattcc atccaagcat tcaccaatat ggaagatgca gtaaaagacg
    12121 cagatgcggt gctattcgtc attccaacga aagcaatacg ttctgttgca aaagaactag
    12181 tgcctaaatt gaatacaaag ccagtgatca tccatgcaag taaaggatta gaacagggga
    12241 cacataaaag gatctctgac atcttgttag aggaaatccc agtagaaaaa agaaaagctg
    12301 ttgttgttct ttctggacca agccatgcag aagaagtagc gaaacatgac atcactacga
    12361 tcacagctgc aagtacagat gcaaaagcag caaaatatgt acaagagctg ttcatgaata
    12421 attattttcg gatctatacc aatcctgatg tgatcggtgt agagatgggg gcagctttga
    12481 aaaatattat tgctattggt gctggcgcta ttcacggctt agggtttggc gataatgcaa
    12541 aggcagcaat catgacgcgc ggattagctg agatcagccg tttaggtgta gcaatgggtg
    12601 ccaacccgct gacctttatc ggattaagcg gagtaggcga tctagtcgtt acttgcacaa
    12661 gtgttcattc taggaactgg cgcgcaggca acttgttagg acaagggcag cccctagaag
    12721 aggtgctagc caatatggga atggtcgttg aaggtgtgaa tactacccaa gcagcgatgg
    12781 aactagccca aataatggaa atcgaaatgc ccatcactca aacaatctat gaagtgctgt
    12841 atgaacaaaa agaaatcaaa acagccgcaa aagaaatcat gttacgtgat gggaaaaaag
    12901 aaaatgaatt ctcattaaca attttttgaa ggagcgaatg tatatgaaag tcaaaaaagc
    12961 agttattcca gcagcaggat taggaacaag atttttacca gcaacaaaag ctatggcaaa
    13021 ggaaatgttg ccaattgttg ataaaccaac aatccagttc atcgttgaag aagcgttgaa
    13081 atcaggtatc gaagacatct tgatcgttac aggaaaagct aaacgaccaa tcgaagatca
    13141 ctttgattca aatattgaat tagaaacaaa cctaagtgaa aaaggaaaga ccgaattatt
    13201 gaaattagta gaagaaacga cagatgtcaa cttgcatttc atccgtcaat ctcatccaaa
    13261 gggtttagga catgccgttc ttcaagcaag agcctttatt ggaaatgaac catttgtcgt
    13321 tatgctaggc gatgatataa tggaagacga agtaccattg acacagcaat taatcgatga
    13381 ttacgaacgt actcatgctt ctacgatcgc cgttatgcaa gttcctcatg atgaaacttc
    13441 aaaatacgga attatcaatc caggagaagt attggaagat gggttataca atgtcaaaaa
    13501 ctttgttgaa aaaccagatc caagcaaagc accaagtgat ttagctatta ttggacgtta
    13561 cttattgact ccagaaattt ttgatgtatt gtccgagcaa caaccaggag ccggaaatga
    13621 aatccaacta actgacgcaa tcgatacatt gaataaaaca caacgcgtat ttgcccgtaa
    13681 attcacaggt aaacgttacg atgtcggtga caaatttggt tttatgaaaa caagtattga
    13741 atatggtcta acacatccag aagtaggtgc acctttacgt gagtacatcc tgtctttagg
    13801 taaaacatta gaagcagaag gaagcaagat cgatcataat ccaaaaggaa taacagaaat
    13861 caaagaagaa aagaaaaaat aacccttttt tctaacgagc ttcagctgct aattgaataa
    13921 aaagtagttg aagctcgttt ttatttgttt aaaaaacacg aaaatgctat ccttatagaa
    13981 aagagagaca agaagggagt ttgatcatgt caggaggaga aattgcagga ttgatcgcag
    14041 caatcgcctt tgcgatactt gtcgttttta tcgttcgtgt gttgttgcaa gtttctaaaa
    14101 ctttagaaaa agtagatcag actgtagcag aagcaaatac gacgatcgaa atcgtcacaa
    14161 aagacgtaga tcttttgtct agacaagtag aaggcttact ggtcaaaagt aatgaactgc
    14221 tcttggatat caatggaaaa gtcgcaacga tcgatccatt gttcacagca gttgctgatt
    14281 taagtgaaag tgtatcagaa cttaatcatt ctagtaaaaa catcgcgacg aaagtcggcg
    14341 gaatcggtaa aacgacagct aaagcgacgg ttgccggaaa agtcggtggg acagcgatga
    14401 aattttttaa aaacaaaaaa catactgaaa cgacaggagg aaaataaaaa tggctaaaaa
    14461 aggtggattt ttattaggtg cagtagtcgg aggcacagcc gcagcaatcg ccgcgttatt
    14521 gttagcacca aaatctggta aagaacttcg ggatgaatta gctgcccaag cggatgattt
    14581 gatggatatg gcttcagatt acacagatat ggcgaaagaa aaatcgactg agttaacagg
    14641 tattgcaaaa gaaaaagcgc aagatctttc tcaacaagca ggtgatctag caggtagtgt
    14701 caaacaaaaa gtaagtgaat cagcagatga agcaggaagt gaatctgacg atatcttgtt
    14761 aaatcttaaa gaacaatcag ctgacttatc taatcgtttc aaaaaaacgg cagaagatat
    14821 gaaaaaacct gcagatgaat taggaagtat tgctaaagat acttcagaag atatcataat
    14881 tgatgtaaaa gacgctgctg gtaaagcagg agatactgtc aatgaaggaa tgtcagaagc
    14941 aaaaccagtt gcagatgact caaaagaaat gatgaaaatg gcaaaagaag atgcgaaaga
    15001 agctaaaaaa gaaataaaag atacaatgac agattcatct acaaatcact aaaatcacaa
    15061 atttatagaa taaaa
//
LOCUS       DAFBSV010000070        14861 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.071, whole genome shotgun sequence.
ACCESSION   DAFBSV010000070 DAFBSV010000000
VERSION     DAFBSV010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14861
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.071"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     misc_feature    110..235
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            279..803
                     /gene="infC"
                     /locus_tag="LLB18_002065"
     CDS             279..803
                     /gene="infC"
                     /locus_tag="LLB18_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBK5245056.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            875..1075
                     /gene="rpmI"
                     /locus_tag="LLB18_002066"
     CDS             875..1075
                     /gene="rpmI"
                     /locus_tag="LLB18_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBK5245057.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            1128..1487
                     /gene="rplT"
                     /locus_tag="LLB18_002067"
     CDS             1128..1487
                     /gene="rplT"
                     /locus_tag="LLB18_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBK5245058.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            1739..3046
                     /locus_tag="LLB18_002068"
     CDS             1739..3046
                     /locus_tag="LLB18_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HBK5245059.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAIFA"
     gene            3123..5252
                     /locus_tag="LLB18_002069"
     CDS             3123..5252
                     /locus_tag="LLB18_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBK5245060.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKQQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEIDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            5227..5916
                     /locus_tag="LLB18_002070"
     CDS             5227..5916
                     /locus_tag="LLB18_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245061.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(6324..7010)
                     /locus_tag="LLB18_002071"
     CDS             complement(6324..7010)
                     /locus_tag="LLB18_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK5245062.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(7146..7340)
                     /locus_tag="LLB18_002072"
     CDS             complement(7146..7340)
                     /locus_tag="LLB18_002072"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245063.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(7390..7830)
                     /locus_tag="LLB18_002073"
     CDS             complement(7390..7830)
                     /locus_tag="LLB18_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HBK5245064.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(7834..8679)
                     /locus_tag="LLB18_002074"
     CDS             complement(7834..8679)
                     /locus_tag="LLB18_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HBK5245065.1"
                     /translation="MLINEQLVKRIITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            8828..10246
                     /gene="pepV"
                     /locus_tag="LLB18_002075"
     CDS             8828..10246
                     /gene="pepV"
                     /locus_tag="LLB18_002075"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBK5245066.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(10303..11250)
                     /locus_tag="LLB18_002076"
     CDS             complement(10303..11250)
                     /locus_tag="LLB18_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBK5245067.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(11473..11823)
                     /locus_tag="LLB18_002077"
     CDS             complement(11473..11823)
                     /locus_tag="LLB18_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBK5245068.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            12023..13102
                     /gene="pepA"
                     /locus_tag="LLB18_002078"
     CDS             12023..13102
                     /gene="pepA"
                     /locus_tag="LLB18_002078"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HBK5245069.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            13246..13566
                     /locus_tag="LLB18_002079"
     CDS             13246..13566
                     /locus_tag="LLB18_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBK5245070.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            13588..14052
                     /locus_tag="LLB18_002080"
     CDS             13588..14052
                     /locus_tag="LLB18_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBK5245071.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            14257..>14861
                     /locus_tag="LLB18_002081"
     CDS             14257..>14861
                     /locus_tag="LLB18_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HBK5245072.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
BASE COUNT         4729 a         2742 c         3107 g         4283 t
ORIGIN      
        1 gaatcactgc tagaaagtct gctaatctaa tcattttcag aaaaggaaga caaactgtat
       61 gaaaaacatt gacaaaaaga ttagtttttg ctatactatg atggttgaga aataaaagca
      121 gaagcacccg cttctcgcct tagttgataa tgtcactggg ctagatagtt ttcactggtt
      181 ctattaggtg aagtacgcgc gggttctgta agagaactcg tttttttatt gccgtttatt
      241 cggtaagctt ttctttctct cataatattt ggaggtgaat gaccatagca aaggatatga
      301 tggttaacga cggcattcgt gcacgagagt tacgattgat cggttcagat ggtgagcaat
      361 taggagttaa gacaaaagca gaagcattga atattgcaga acaagcaaac ttggatcttg
      421 tgttagttgc ccctggtgcg aaaccaccag ttgcgcgaat catggactac ggtaaatacc
      481 gtttcgaaca acaaaagaaa gaccgcgaag cgcgtaaaaa acaaaaagtg atcaatgtaa
      541 aagaagttcg cttaagtcct acgatcgact tgaatgactt caatacaaaa cttcgtaatg
      601 cacgtaagtt cttggaaaag ggcgataaag tgaaagcttc tatccgtttc aaaggccgtg
      661 ccattaccca taaagaaatt ggtcaaaaag tcttgaatcg cttagctgaa gaaactgcgg
      721 atattgcaac agtggaacaa aaagcgaaaa tggacggacg cagcatgttc ttgacgctgg
      781 caccgaaaaa cgacagtaag taatttgaat gactaactgg ctgttggaca gccgatagtc
      841 ggataacgaa agattttgag gaggaaatat agtcatgcca aaacaaaaaa cacaccgcgg
      901 atcagcaaaa cgtttcaaac gtactggtaa aggcggattg aaacgcttcc gcgcgtttac
      961 aagtcaccgt ttccacggca aaacaaaaaa acaacgccgt caattgcgta aagcaagcat
     1021 ggtttctagt ggcgacttca aacgtattcg ccaacaacta gcaaaaatga aataagaagt
     1081 acaaataaca gaatctgaag atttattttt attaggagga attatacatg gcacgtgtta
     1141 aaggtggaac agtaactcgt aaacgtcgta aaagagtgct aaaattagca aaaggttact
     1201 acggttcaaa acacacttta tttaaaacag caaaagaaca agtaatgaat tcatacaact
     1261 acgcatatcg cgatcgtcgt caaaagaaac gcgacttccg taaattgtgg attgctcgta
     1321 tcaacgcagc agctcgtatg aatggcttga gctactcaaa attaatgcac ggtttgaaag
     1381 ttgctgaaat cgacatcaac cgtaaaatgt tagctgactt ggctgttaac gatgcagcag
     1441 catttactgc attggctgac caagcaaaag aagctttggc taaataagct aaacaattat
     1501 aaagaggaaa gaagataacg aaaagttatg ttctttcctc tttttttatt tacaatcctc
     1561 catcaaatga aacaggacaa taacgtataa gtctaaaata gcataattaa ggttttttaa
     1621 ttgaaaactg aacatttatg gtcacccttt aatgaaagcg ctaactacat aagttagaat
     1681 gagtttgact gatatattag tttgcttatc agaaaaacaa aatggacgga ggaataacat
     1741 gagtgatatt attattggta ttttgttagt tatctcattc tttttcatgg tctggtactg
     1801 tgtaaaaggc tacaacttga tggtcggctt tgccatcatg gctactgtat ggatgggatt
     1861 agcgctagtc ggaaacacgt tttcaccaaa cccggcgatg gaagggcaag gagtaattga
     1921 tgtgttgacg catatctata cgacggggcc agctgagtac gccaaatcga tcttggtaaa
     1981 tgtcttcttt ggtgcctttt tcgggcgtgt tctagtagat agcggaatcg cagctaccct
     2041 gattcgaaag gtagttgaac ttggagggga caagccaaga atcacgatga gcttactatg
     2101 tattgtaacc gctgttatat tcatgtcgat gacaggaatc ggaccagtga tttctattgc
     2161 agttattgtg ttgccaatct tgatgtcatt aggtatttca gtaccggttg cactgttctc
     2221 atttatgggc tcgattatgg ctggaatctt tgctaatatc gtcaatttca aacaatatca
     2281 aacgatttat gctggtttca atccagcggc tgaaagctat acttataatg actatttcca
     2341 aattggtatg attgggatga ttgtaagctt agttgtggta ctaacggtcg ctaatatatc
     2401 aatgaacaaa aagaaacgct atgcaatggc agcaaacgta ccagctgaag gtggcgacgc
     2461 accaatgatc tcatggttag ccgtattatt accagtttta ggggtcgttc ttttagatct
     2521 tccaatcatc ttaggtttta ttctagcagg tatctgggca ttgctgttta ctggaaaatt
     2581 gcgcggaggt tataaagaaa tctgtcgtca gtttgcgaaa ttatttacag atggcgcagt
     2641 agatgttgca ccaatggttg gtttcttgat gaccttagcg atgttcaata attcagctgc
     2701 gtatgcttct ccttattttt cagctatttt tggagattgg ataccgcaat caccattagt
     2761 cttggcaatc gtatttgcta tattgacacc actaggattt ttccgcggtc caatgaatct
     2821 agtcggttca ggctcagcta ttttagctgt cgtattagct gttaatccaa cgatgtcgcc
     2881 agcctttttg ttcccgttat ttgcaatcac aacgattgct cctcagcatt tagatattac
     2941 acaatcttgg gttgcttggg gattaggtta tacaaaagta acttctcgag aatatatgaa
     3001 gaaatccatc ccaactggtt ggatcatcgg agcgatcttt gcctgatcac gttcttattg
     3061 tacgggaacg cctagtaaac aaaacgtcga taaaaacgat tagatgaatg gaggaaaaga
     3121 aaatgaaacg ttttgtgcga atgggaattg atgttggcgg tacacatacg aaagcagtcg
     3181 caatcgataa tgcgacgcac gaaatcatcg gaaaatcttc agtgaaaaca acccacgatg
     3241 atgtccgtgg agtagccgca ggtgtcgttc agtcttttca aaattgtttg cgggaaaata
     3301 atatcagtcc agaagatgtt gtgtttgttg cacattctac cacacaagcg actaatgcac
     3361 tgattgaagg agacgtagca aaagtcggcg taatcgggat ggcaaaaggt ggattagaag
     3421 gttttttagc aaaacaacaa actagattga acgatatcga tttagggaat aagaaaaaaa
     3481 tagagattgt caatgcattc ttacctgtca aacacttaaa tgtagaccgt gtttcagaaa
     3541 cgatttcttc tttagaaaga gaaagagcgg aggtcttggt ttcttctatg gcatttggag
     3601 tagataatgg ggaaccagaa cgagttgttt atgaagcagc atcggtaaaa tcgatcccta
     3661 caacgatggc ttctgacatc acaaaattat atggattgac aagaagaact cggacagcag
     3721 caatcaatgc atctatttta ccaaaaatgc tagatacggc aacctctaca gaagattccg
     3781 tacgagaagc aggggtcaat gtttctttga tgattatgcg cggagacggc ggagtaatgg
     3841 aaatcaatga aatgaaaaaa cgacctgttt taaccatgct ttccggtcca gcagcatcag
     3901 tcatgggctc tttgatgtac ttgagagcgt ctaatggtgt ttattttgaa gtaggcggaa
     3961 caacaaccaa tatcggggtc attaaaaatg gacgtccagc aatcgattat tcaattgtag
     4021 gtggccaccc aacatatatc tcttcattag atgttcgggt tctaggtgtg gcaggcggtt
     4081 cgatggtacg ggctaatcag tcaggaatca tcgatgtcgg tccacgttct gcacatattg
     4141 ccggtctaga ttatgcagta tttacggaga cagaaaaaat caaaggtcct aaggttgaat
     4201 ttttctctcc taaagaagga gaccctgctg attacgtcaa ggtagtgatg gaagacggag
     4261 aagaagtgac tattacaaat acatgtgcag ccaatgtcct tggattagtg caagaagaac
     4321 atttttctta tggaaatgtc ccatctgcac gaaaagccat ccaagcatta gctgattatt
     4381 gtcatacgac ggttgaagac atcgcagaac agatcatgga aaaatcctat gctaagattg
     4441 aaccggtgat tttagaattg gcagacaagt atcacttgga gatagatcag atttctcttg
     4501 taggtgtagg gggcggcgct gcctcattga ttacttactt tagtaataaa atgggtgtga
     4561 aatattcgat tcctgaaaac gccgaagtga tttcttctat tggtgtagca cttgcaatgg
     4621 tccgagatgt tgtagaacgt atcatccctt cgccaagtaa agaagatata cgatcgttga
     4681 aaaatgaagc gatgaataaa gcgattgaat caggcgctac accagaatcg atcgaagtcc
     4741 acgtagaaat cgatccacag acttcaaaag taacggctat cgctactggt tctacggaag
     4801 tgaaagcaac cgatctaacc aaggagatca caacagaaga agcactagag cttgctgcag
     4861 aggatatgcg attaaataaa aatgaagttt gcttattgga aaatacacct ttcttttatg
     4921 tatgcggcga acagaatcgt tcaaaaaatg ctggaagtct tcggatcatc gatcaaaaag
     4981 gatttatcaa ggtccaacgt ggacatgctt catgtatgaa aacaactgca gccaattata
     5041 tgacagctgt cgaacaactt tgggaagata tggcagttta tcaaactgaa ttgattgccc
     5101 gaccagaatt ttatctctgc ttaggagcaa gagtctctga ttttacagcg acggatctgg
     5161 aacaactaca gcttttgatg gatctggaag tatctactat ggaaccggag gaagaagtga
     5221 tcgtcgttgc cggaaatatc aaacaaacat aagttagaag agttactaaa cgaattacaa
     5281 cagatccccg aagaaatttg gggattctac cagtttcggc gagatttatt ttggaaaaag
     5341 attcctttgt ccaagcagaa aattcttata caacaatcaa tcgattgtgg tatcgaaacg
     5401 gcatgtagca tcaaaaaaaa gtaccctttt gccgatgtag gagaaatttg tgaacaaatg
     5461 gctgttccaa tcgtttcctg tgaatcagag caaataaacg aacgaatcac ttttgcaact
     5521 tatgcagaag atgaagggat tcgattgatg acggagccgt tagaaaaatt aaaatgttca
     5581 ggactagctt cgatctctaa agaaacagcg caagctttga ttattggaca tgaactattt
     5641 caccacatcg aagcttctgt taagggaatt tatacgcaaa gcgaaaaaat tgtgctgtgg
     5701 cggttgcctt tttatacaca tcaatcaaac attcgtgcat tgagcgagat agcagcgatg
     5761 agtttttcaa aagagatgaa tcaaagcgat ttttcgcctt atgtattaga ggcagtctta
     5821 ctttggccat ataatgaaat tcgtagccaa gggatcttag aagaaataaa aaaaatagaa
     5881 aaaagatgta cggagtatga tttagattac aaataaagag actgtgacaa aagtcgtgtc
     5941 acagtccttt ttttccgaat aaacgatgtt ctcctgtcaa ctcctcggtc acaagtcaaa
     6001 atattcaaca aacatgagaa gctgtttttt gaaattgttc cttgtgactc ggagatgaac
     6061 ggcaggctca cgacctcttg gaaaacggtg ttcaaaagct tgcatctgcg gtaataagtc
     6121 cagccaagtt aaaaacataa gaagctattt ttacttggct gttcttatta cttgatgcag
     6181 ggcagctttt tcacaacctc tcaataaacg gtgtgcaatc agctgaccct cggtattagc
     6241 tcaaaaaaaa cggcaaaata tgaggaacta ttttgccgtt tctttctcta atactcaggt
     6301 caaaacgctg attccaaaac ctcttatttg atgggtctgt cctgaatatc ttcaaaataa
     6361 tcggggtaat tatgaatcac gtattcttgc tcctcgataa tcatatgtaa atgcatcgtg
     6421 caaagaaatc cgacttcatc aaagttatga tcaatcattg attgaagcat tgtctgatgt
     6481 tcatctaata ctcgacccca gtctaattct gaaatcgtca aacgtaacca tctgaaacgg
     6541 ttcaagtgcg tactataact ttctagccaa tcccaaattt ctcgttttcc agcaatttca
     6601 taacaagttc ggtgaaaatc agtatccaaa tcaaaaaaag cttttttatt ttgagcgatt
     6661 actgcctgat cggtttgttc tagtattttt tctagtttag cttgatcttg cttggtcatt
     6721 ttcgcactgc attcttgcag gatcggtttt tccaactttt cccgcgtata acgggctaat
     6781 gaagcagatc ggatatcgat ttttgaaaca taagtgccgg actgtggaat ggtttttaca
     6841 agctcttgat tgcgcagttg gatcagtgct tctcgaatcg gtgtacgccc gatagctagt
     6901 tgttcttcta acactttatc ggagatttta cttccaggtg ctaactcgga ataaatgatt
     6961 tgtttacgta tagattcata agcttgctgt tgcaaattat tgataaccat ttaaccttcc
     7021 tttctatgca gatataatct attataacat aaatcgctta caaatcgtgt gggcataaaa
     7081 acacagtctg caaaaaaagc cctgataggc atgcctatta gagcctcgaa aagaaaaata
     7141 ttgaatcaat ctggtcgtac ctcttgtatc ggtttgacac gaccgccgat tcttttagca
     7201 aaagcttcgg attctttttt gtctttgaaa atgagcagat tgtctaagtt tttttcccga
     7261 gtgcgacagc cagttttatc gatgtaaccg tgcattactt taacgacata catggggatc
     7321 acctgctttt ttcttttcat tatacgaact actcgacaca atacaagaaa aatgcttaga
     7381 cggtctttat taagaattta catcatccaa agaagcgtac gcttggaata actgatctaa
     7441 ctccggattg actttgctca gcttcactaa tcgttgcgaa tcagaaagta aaaaacagtg
     7501 tttactactg ccagtagttt ttaatttttt gtcttcagtt cccacaattt cgtagctaaa
     7561 atccaaccgt gtccccgtat acttttggat agttggatgg atgctcactt tttctccgta
     7621 atggatcatt tctttatagc tgcaatttac ttccagaacg gggatgatga tcccagattc
     7681 ttcgattttt ttatagggaa accctagatg taccaataag gctacccgag cctcttcaaa
     7741 ccagcggata taattgctgt gatgaataat ccccatttga tctgtttcat aataaaaagg
     7801 ttctcgcaca taacctgtaa atttctccat gactcatgcc tcgttttcca ttgatttttt
     7861 acaaaaataa ttcatccatt tcggaagtgc ttcgctgatt tgtgtcggca aaacaatata
     7921 ttgttctttt gccagctggt ctccaatgaa actatgaaga taaatagctg ctgcaatcgt
     7981 ttggtcattt tgaggaaact gggctaaaaa tcctgtgatc atcccagcta aagtgtcacc
     8041 catgccgccc gttgccatag cagcagaacc taaaggattg gtgtagaagt gctggtgacc
     8101 ataaattttt gtctcatgac ttttcaaaac gagcacagca ccgatttcct gttgcttctt
     8161 tttgttttct ttatcccgtt gttcttgtat cggtagagaa ctcaaccgtt gccactccat
     8221 ttgatgaggt gtaagtacag tttgttcggg atagggtagc aaaagatgat tagcagcaag
     8281 taaacttaaa gcagagccat caatcaccag ccattgttct tttgattggt tttctagtac
     8341 ttgtttgaaa cgttccaaac tcttagaaga agtacccaat ccgggaccaa tcaagagtac
     8401 atctgcttgc tttattacgg aaagaaactg gtcagtatcc gtccaaacta caatcattgc
     8461 ttctggcaga tgactgtgaa gagcactccg atttttttca tcagttacta cagtcgtgag
     8521 acccgctccg ctgtgtacgg cagctaaagc actcataatg attgctccgc catattgttc
     8581 attgccgcca atcaaaacga tacgtccaaa tgttccttta tgtgaaattt ttggacgagg
     8641 tgtgatgatt cttttcacta gttgttcgtt tatcagcatc taaaaacctc cttttactca
     8701 ttatagcgta tatttttttt agagaaaaac agataagaaa aggaattgtc agattttttg
     8761 aactattttt ttctgtaatt tgtggtatca tgaacacgaa gacttaaata agtggaggat
     8821 taactttatg acaattgatt ggcaaaaaga agtagaagca cgtaaagaag acttgcttga
     8881 agacttgaaa aatcttttac gtgtcaacag cgagcgcgat gactcaaaag taacaccaga
     8941 tgcaccattt ggacctggac ctcgcgacgc attgaaacat atgttagctt atggcgaacg
     9001 tgatggattt aaagtaaaaa atgtcgataa ctatgcaggg catattgatc ttggcgaagg
     9061 agacgaaacg ctagggatat ttggacacat ggatgtcgtt cctgcaggag atggctggga
     9121 cacagatcct tatgaaccag taatcaagga tggaaagatc tttgcacgcg gatcaagcga
     9181 tgacaaaggt ccaagtatgg cagcttacta tgcgatgaag atcattaaag aacttgactt
     9241 gaaactatca aaaaaagttc gcttcgtagt cggcagcgat gaagaaagcg gctggggcga
     9301 tatggcttat tatttcgaac atgaagaaga accagatttt ggtttctcac cagatgctga
     9361 attcccaatc atcaatggtg aaaaaggaaa tgtttcttta gctttacgct tcaaaggcga
     9421 caatgcagga gattatgtct tgaaatcttt tgtttccgga cttcgcgaaa atatggtgcc
     9481 aggaacagca actgcagcac ttcaagtacc aagtgcagat gcagctatcg cgatggaaga
     9541 agcattttac caattcatcg aagcaaatcc agtaagcgga acgattgaag cggacaatac
     9601 gtatgtaaaa atcgaattag ttggtaaagg cgcacatggt gcaagcccac aatctggtat
     9661 caatgcaggt tctttcttgg cattgttctt agataactat gaattcctag gatctgctaa
     9721 acaatttatc catgtagcag ctgcttatgt ccatgaagat ttttatggag aaaaactagg
     9781 agtcgcttat gaagatgaaa aaatgggcaa attgacaatg aatgctggac tatttgcttt
     9841 tgaagaaaat ggtacagagg aagcgaactt catcaatatg aatttccgtt ttccaaaagg
     9901 tgtaacagta gacggattgc aaagtgacat cgaacaaaca gtggggcaag aaggcgcaac
     9961 agttactcga ggtgctcgcg taatggaacc acattacgta ccaatggatg atccattggt
    10021 ggctacatta ttgcaagtct atgaagacca cactggagaa aaaggctacg aacaaatcat
    10081 cggtggcgga acttacggac gtttgttgaa acgtggcgtt gcttatggag cgatgttccc
    10141 aggatatact gatacaatgc atcaagcaaa cgaatttatg agtcttgatg acttgttcag
    10201 agcaacagca atctatgcag atgccatcta tcgtttggcg aaataattaa ttaaaaagag
    10261 gatcaagaat tgcaaattat ttttgcagtc ttgatccttt ttttactttc tactgtggta
    10321 ttcatgataa acatgatata gattcaattc atattctttc ttagcgttcg tgacgactgt
    10381 atccaaaatc aaccctgtta ctaatgaaag aagtgctaaa gtcatcaatc cagtacttaa
    10441 aatcgcagaa gggatgcgtg taataaagct tgtcagcata tattcgcgaa tcacaggaat
    10501 ccccgtgacc aatccaaata aaaagaagaa gatggtccaa atcccaaaga aaagcaaagg
    10561 cttataatct ttaaacattt taataatcat catgatcact ttgaatccgt cagagaatgt
    10621 attcaatttt gattcgctgc cttcaggacg atcacgataa tcgattggga tttcaacgaa
    10681 cttgaatttt ttatctaaag catggatcgt caattccgtt tcgatttgaa aaccagaact
    10741 cataatagga aaacttttga caaagatacg attgaatcct cgatagccgg tcatgacatc
    10801 aagaattttt gttttataca ttctagtaat tgtatttcta acaaggttat ttccaaaatc
    10861 gtggaaaggt ctcttattct catcaaagta ggttccattt gataggcgat caccaatgac
    10921 catatctgct tcaccagaac gtaatttctc gagcaaacca tgtacagctt ctgcaggata
    10981 agtatcatcg ccatctacca ttaaataata gtcggcatcg atatcaaaga acatttggcg
    11041 gatcacattt ccttttcctt gacgaggttc tttttttacg attgctccac cttgaacggc
    11101 caattcgtat gttcgatcgg tcgaattatt atcatagaca taaatatctg cttctggtaa
    11161 ttctcgttta aagtctgcaa tgactgttga aattgttgct tcctcattgt aacaaggaat
    11221 cagaacagca attttttctt gttgttccat ttttcactct ccttaactat agaaaacaaa
    11281 agctaaatta aaaatacctc ataatcaaag gaaatgctag tttttcccgc taaatatcat
    11341 ttatttaaaa agaaaatact ggaatatatg tttggaaagc tctatctaaa aaaccaccca
    11401 ctacaaaaga aggacatgat acctctcttt tgaatagtgg gtgcgtattc gttctctcac
    11461 ttttttgacg tattaatctg ttgcaccttt ttttcttgaa atttctaata cggttcctgt
    11521 atgagcatct gctaaaaatt cataataaac agtttcgcca tcttctattc gagaaagacc
    11581 tccccgataa gcactcgacc gaacggcgaa tttcctaata ggttcctttt caaaagagat
    11641 ccaagaacct tcgattgcac cttcttttag aaaagatgac ttgatatttt caagtacttg
    11701 gtctgctgac aatacttttt tgcgatgata ccaaatcgtt gaagctaccc cgctcaataa
    11761 tcctagaccg attccaactg ctaacccgcc tttaaaatag cttagttcgc tttcttcata
    11821 catgtggaca tacctccttc ttctcacttg ttactccttg tgcttatttt accacactct
    11881 catattttct ttgaaataaa taaccgctac cagaaaaaat aagctataat aaatacgatc
    11941 ggtctgcaga aaaaatcata ttttatccgc agatcaatat aagtctgaga ggagtttagt
    12001 ctgaaattta gacgaatagc atatggaaga aaaaacattt caacgaatca aagagttaac
    12061 agaattacaa ggaacaagcg gttttgaaca agatgttcgc gcttatatgg aaagtcatat
    12121 ggaaccgctg gtagatgagt tacagttaga tggtttgggc ggcatttttg gtctgcgcca
    12181 tcatgaagaa gcggatgcac cccgtgtaat ggtcgcagca catatggatg aagtcggatt
    12241 catgctgaca caaatccaag aaaacgggct ttttaaagtc gtacctctag gcggctggaa
    12301 tccttacgtt gtttctgctc agcgttttac acttaaaacc tctactggta agaattatcc
    12361 atgtatttct tcttccgttc ccccacattt attgcgagga acaagcggac aaaaatcagt
    12421 agaagtaacc gatattttgt tcgatgctgg gtttgaatca agagaagagg caatgagtta
    12481 cggtgtcctt ccaggagaca caatcgttcc ttacgctgaa acgatcaaaa cagccaacgg
    12541 aaagaatatt atcagtaaat catgggacaa ccgctatggc tgtacaatgg tattagaagc
    12601 tttagaagcg ttgcaaaatg aaacattagg tcatacattg attgcaggcg cgaatgtcca
    12661 ggaagaagta ggcttgcgtg gttctaaagc ttctgtcaat aaattcaagc cagatctgtt
    12721 ctttgcagta gactgctctg cagcagatga tacagtgacg aaaaatggca cattcggaca
    12781 tttaggagaa ggtacattga tgcgtatcca agatccaggt ttgatcatgc ttcctcgttt
    12841 gcgcgagtac ttgctggata tcgctgaaac aaacaatatc ccttatcaat actttgtttc
    12901 aaaaggcggt acagatgcag gtgctgctca tacacaaaac gaaggaatcc caagtacagt
    12961 gattggcgta gtgggacgtt atatccatac gcatcaaacg atgttcagta ttcgcgattt
    13021 tgaagctgca cgagaaatgt tgattcaaac actgaaaggt ttggataaat caacagtgaa
    13081 tacgatcgta tacggaaaat aatgcgatag tgaaactata aaatctggca aaagattgct
    13141 ttttgccaga ttttttttat aaaaagagga tcaatgtttg ttagttcgaa agaaaggtgt
    13201 ataatttaat tgaaaaatac ataaacagaa agtagaggac aaagaatgat tatcccaaat
    13261 agtttagaag aattagcagg ctacgtagaa actggaaaga gtgtattttt ctttactgcc
    13321 ggctggtgcg gagactgccg ttttatcaaa ccgcaaatgc ctgaaattga aaatgacttt
    13381 tctgattggc aatttattga agtagaccgt gacaagtaca tagatgtagc cgctgaatgg
    13441 aacatttttg gtatcccaag ttttgtcgtg atccaagacg gaaaagaatt aggtcgtcta
    13501 gtgaataaag atcgtaaaac aaaacaggaa atcgaatcgt tcctagaaag tgtaacaaaa
    13561 ggctgacatc tgttaggagg ggtcaagatg aatcaagaat ataagaatat tttagtaggt
    13621 atcgacggta gtgaacaagc acttgctgct ttcaaaaaag cggtagaagt ggctcgccgt
    13681 aataatggga aagtatatgt agcaaacgta atcgatcagc aattttataa ctttatgggc
    13741 tatgcaccta ttgatcaaaa tctagtcgat cagcaaactg aaacagccaa ggaaatgatc
    13801 gaagaatgta aagaatatgg gaaatctgtt gattacacaa atatagaagg aattattgca
    13861 tatggttctg ttcgtgaatc catggcagtc aaattgccaa aaaaatatga gatcgatcta
    13921 atcatggttg ggcagtcagg tctaaatgca gtcgaacgct ttatgacagg aagtgtagcc
    13981 agctacgtga tacgtcattc accttgtgat gtcttgatcg tttctgacga agaagaacag
    14041 ccaagtaatt aagcaagtgg aacttgtacg acctttttaa tcaattaact aaaacagtaa
    14101 agggactgtg acaaaagtct tgtcacagtc ccttgttacg aataaatggt gttccagaag
    14161 aggcttcttc ggaaataaag catgaaaaaa atttcatgca gtgaatgcaa ttttttgtta
    14221 agataaatct cagcaaagga taatggagga aagaacatga tttttgctta taacaaagca
    14281 cacgtcggag acaccttgat ggttattata gccgacgata aaggaacaga aaacactgtt
    14341 gaacgcaaat ggaatgttgc tcggatcaaa gatgaacaag gtcaagttgt tgcttggaac
    14401 tttttccata tctccgatca tctaacaatc gaagggaacg gccaagtaag cttaacagat
    14461 gaggaattag cgaaattgaa tcgattgatc aaagaagcag gattcgaaga acagcttgaa
    14521 gctgatcatg aaccgaagat cgttgtcggg tacgtaaaaa catgcgtccc acatcctgat
    14581 tctgaccatt tatcgattac tgagacagaa gtagacaatg gtacagtatt gcaaatcgtt
    14641 tgcggtgcac ccaatatcga agctggacaa aaagttgtcg ttgcaaaacc aggagctatg
    14701 atgccagatg gaatgatgat ctggccagga actttgcgag gggtagatag ctatggaatg
    14761 atctgttccg ctcgtgaatt gcatttgcca aatgctccag caaaaaaagg aatcttagta
    14821 ttgcctgagg atgccgtagt cggagaagca tttccaaaat a
//
LOCUS       DAFBSV010000071        14566 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.072, whole genome shotgun sequence.
ACCESSION   DAFBSV010000071 DAFBSV010000000
VERSION     DAFBSV010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.072"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            5..847
                     /locus_tag="LLB18_002082"
     CDS             5..847
                     /locus_tag="LLB18_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBK5245073.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            847..1794
                     /locus_tag="LLB18_002083"
     CDS             847..1794
                     /locus_tag="LLB18_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBK5245074.1"
                     /translation="MRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVVT
                     NSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETGG
                     NAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKNI
                     EKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYFS
                     KAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDTN
                     IPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            1809..2042
                     /locus_tag="LLB18_002084"
     CDS             1809..2042
                     /locus_tag="LLB18_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HBK5245075.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            2373..2957
                     /locus_tag="LLB18_002085"
     CDS             2373..2957
                     /locus_tag="LLB18_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK5245076.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            3088..3755
                     /locus_tag="LLB18_002086"
                     /pseudo
     CDS             3088..3755
                     /locus_tag="LLB18_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
     gene            3766..5181
                     /locus_tag="LLB18_002087"
     CDS             3766..5181
                     /locus_tag="LLB18_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBK5245077.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQNPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            5199..5768
                     /locus_tag="LLB18_002088"
     CDS             5199..5768
                     /locus_tag="LLB18_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HBK5245078.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVVSWVLMQLGSAAGQWIPIWFFTDRFRQDWIDRGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            5878..7632
                     /locus_tag="LLB18_002089"
     CDS             5878..7632
                     /locus_tag="LLB18_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5245079.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQYLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHRVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            7592..9358
                     /locus_tag="LLB18_002090"
     CDS             7592..9358
                     /locus_tag="LLB18_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5245080.1"
                     /translation="MQMIGGLTMKNFYKKKFALTDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENAKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            9881..10150
                     /gene="rpsN"
                     /locus_tag="LLB18_002091"
     CDS             9881..10150
                     /gene="rpsN"
                     /locus_tag="LLB18_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBK5245081.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            10165..10344
                     /gene="rpmF"
                     /locus_tag="LLB18_002092"
     CDS             10165..10344
                     /gene="rpmF"
                     /locus_tag="LLB18_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBK5245082.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            10376..10753
                     /locus_tag="LLB18_002093"
     CDS             10376..10753
                     /locus_tag="LLB18_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245083.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            10774..10923
                     /gene="rpmG"
                     /locus_tag="LLB18_002094"
     CDS             10774..10923
                     /gene="rpmG"
                     /locus_tag="LLB18_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBK5245084.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            10947..11930
                     /locus_tag="LLB18_002095"
     CDS             10947..11930
                     /locus_tag="LLB18_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBK5245085.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            11960..12082
                     /locus_tag="LLB18_002096"
     CDS             11960..12082
                     /locus_tag="LLB18_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBK5245086.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            12100..13623
                     /locus_tag="LLB18_002097"
     CDS             12100..13623
                     /locus_tag="LLB18_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBK5245087.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            13647..13886
                     /locus_tag="LLB18_002098"
     CDS             13647..13886
                     /locus_tag="LLB18_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5245088.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(14079..>14566)
                     /locus_tag="LLB18_002099"
     CDS             complement(14079..>14566)
                     /locus_tag="LLB18_002099"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBK5245089.1"
                     /translation="GNKGLIRSLHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDR
                     SDFGHWKADIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPN
                     EAVKTITPDRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRK
                     R"
BASE COUNT         5113 a         2009 c         2739 g         4705 t
ORIGIN      
        1 taatatgctt caaaatttta ttaatggtct gtatgacttt cactttttac agaatgctct
       61 aattacatct gtagttatag ggattgtttc tggaacagta ggttgtttta ttattttaag
      121 aggaatgtct cttatgggtg atgctatttc tcatgctgtt ttgccaggag tagcaatttc
      181 ttatatttta ggtattaatt tttttattgg tgcgattgta tttggtctat tagcttctat
      241 cattattact tttataaaaa gcaatagtgt aataaaagga gatacagcaa ttggtattac
      301 tttcagttct tttttagcat taggagttat ccttatagga gttgcaaata gctcaacgga
      361 tttatttcat atcttatttg gaaatatttt agctgtacaa gatattgata agtggattac
      421 aattggcgtt tctgttttag tgttggttac agttgttcta ttttttaaag aattattaat
      481 cacttctttt gatccattaa tggcaaaagc aatggggatg aatgtcagtt tttatcatta
      541 tctattaatg attctattaa ctttagtagc agtaacagct atgcaaagtg tgggaactat
      601 attaattgtt gcaatgttaa ttacaccagc tgctacagca tatttatatg caaacagctt
      661 aaaaactatg atatttattt cggcgacagt cggagcgtgc tcatcattgc taggtttgtt
      721 cattggttat agttttaaca tagcagcagg atcaagtatt gttttaacag cggcattctt
      781 atttgtaatt agttttctaa tctcaccaaa acaaaaattt ttaagaaaga aggagagaaa
      841 gttatgatga gaaaatggaa agcagtactg ggaagtctgg ggattttgat tgctcttttt
      901 atattcgggg catgttcaac aaatagtaaa gacaaagata cagtggcttc gaacgaaaaa
      961 ttaaaggtag tagttactaa ttcgatttta gcagatatta ctgaaaatat agcaaaagat
     1021 aaaattgatt tacacagtat cgtacctatt gggaaagatc cccacgaata tgaacctttg
     1081 cctgaagatg ttcaaaaaac ttcaaaagca gatttgattt tttataacgg tgttaacttg
     1141 gaaactggag gaaatgcttg gtttacaaaa ttagtaaaaa atgcgaacaa agaggaaaac
     1201 aaagactatt ttgcagcaag tgatggcata gatgttattt acttagaggg tcagagtgag
     1261 aaagggaagg aagatcccca tgcttggtta aatttagaaa acggtattat ttacgctaaa
     1321 aatattgaaa aacagttagc ggaaaaagat cctgataata aaaaattcta taaagaaaat
     1381 ctagataagt atattgaaaa attggattct ctagacaaag aagctaaatc taaatttgct
     1441 tcaattccga atgataaaaa aatgattgtt acaagtgaag gatgctttaa atatttctcg
     1501 aaagcgtata atgtgccttc tgcttacatt tgggaaatca acactgaaga agaaggaaca
     1561 ccagatcaaa taaaacactt agttgaaaaa ttacgcacaa caaaagttcc ctccttattc
     1621 gtagaaagca gtgtggacga tagaccaatg aaaacagtat caaaagatac caatattcct
     1681 atctattcaa cgatttttac tgattcaatt gcagaaaaag gacaagatgg tgatagttac
     1741 tatgcgatga tgaaatggaa cctggataaa attgctgaag gcctttcgaa ataatttgga
     1801 gggtaggtat ggtacaaatt aaaacgacta ctatactaat ttatttacta gcaattcagg
     1861 aattatcaaa aagaaaaaag aaattaaaaa ataatgattt agcaaaagtt ctaagtgtta
     1921 gtccagcatc tgtaagtgag atgctggcta aacttagata tgaggactat ttagatatag
     1981 gatttcaatt aactgataaa gggaaaaaat ttattgacga ttacaaaaaa ggttttaagt
     2041 aaaagacttt atttttaggg aggataagaa aatggctatt ggagtgatta tgataggact
     2101 taccctaata gctggatata atttttttaa atctttctcg gattatttta gaaaaggtga
     2161 atgatttaga tgagtctatt aattcttgta ggattgcttt ttgtatcagt tattttgctc
     2221 tttctcatta gtttagctct aaggaatgag ttcagtaata gacgttaacg attgaaactt
     2281 caagtcctgt gtaagataat atagttaatt catcttatta ggaggaagta cccatagaaa
     2341 ccagagatta tattacaact caccaaaaat taatagaaag tggactaagc cattttgaaa
     2401 aagaaggatt tcagcaaact aagataaggc aactgtgctt gaccgcaggc gtaactacgg
     2461 gtgcttttta taaacatttt acttctaagg aagcgttatt tgaagaaatt attcagccgc
     2521 atattaatgc gcttattaat atgtataatg aagagtttac caaatacctc ttaaacttag
     2581 aaaatataga tatagagaaa agttggagag agaacttcaa tgaattagat ccatttatta
     2641 attatatttt tgagaataaa cgtatattcg atttggtttt attccaatca gctggaacca
     2701 aatatcaaga tattgttgaa aaaattacat catttgtgac aaaaaagaca gtctgttgtc
     2761 tagataagtt aaagactatc ggaatgatca atcaaaattt agtctttaat gaagaagaaa
     2821 tccacttcta catttactca ttctacgcta cattctatga tatattgaag catagctatt
     2881 caaaagaaaa gactatgcta ttaaccagaa gattgtatca attttctgtt cctgggtgga
     2941 ttgaattact gagttaatta aaaaaaagct tgcattgaga attgttctca gttatgcttt
     3001 ttgataagat cgcactgtta tctgaataac ggtgcatttt tgtcagctta agataacagt
     3061 gcgatcttat tttttggagg tgaaagagtg tcaaaaatca atccgttaac cttgattact
     3121 ttaaatattt ttttccggtc attatttttt taggaaaggg aaatatattt caagtggggt
     3181 gtttcattat tgctacagtt ttagtattga tgtttcgtaa aataaagaca tgtatttatt
     3241 tcatcttgat ttattcagtt ctgtttttag taatgaaaat tattgatgct atcaagatag
     3301 agttttttac tatatttttt gggacatcct tatatattgt atttcgaatg ttgccggtcg
     3361 taatgatctc atggttgttg gttagtgtct atactagcaa tgaattatta tcctctttag
     3421 aaaaaataca tttaccgaaa aaaataatgt taagtattac agtagtgatc agattctttc
     3481 cgacttatcg ttctgaaata agaatgatta aagaatcttt aaaaatgaga aacattcgct
     3541 tgtctttttt tcagcctctg caatatttgg aatttctgtt agttcccgtt cttatacgtg
     3601 caactatgat tgctgaagaa atgaccgcta atgcaataac aaaggggata gaatctcctg
     3661 tgaaaagaag ttcttactat aaaacaaaca tgagcttatt agactatatc atcctgtttt
     3721 ccgttactat ttttttctta agtattttga tttgaggtga aagaattgtt tgaatttaac
     3781 aatgtttctt tttcatataa ggatgttaag gaacaagcgc ttgttgacct taatttttca
     3841 ataaaaaaag gcagtcttac attgattact ggttcttctg ggagtgggaa atccacacta
     3901 ttaaagttaa tgaatggact tattccaaga ctttatgacg gaaaattggt tggggaaatt
     3961 ttatttgaaa ataactcgct acaatcctta acacaagaaa gtatatcaaa aaatattggc
     4021 tacgtaagtc aaaatcctag aggacaattc tttacaacaa atacaacgag tgagttagta
     4081 ttttcgatgg aaaactttgg atttacaaaa gagcatatgg ataaaagaat caatgaatta
     4141 gctgaattat tagatctttc aaatatatta gataaaaaca ttttttcgct atcaagtggt
     4201 gaacggcaga aaatttctat tggatgtagt ttatcgctaa actctaaatt aattatattg
     4261 gatgaaccgt cttcaaattt ggacttcaaa gcgactaaga aacttgctga cttactttgt
     4321 gatttaaaaa ataaaggatt tactattgtt atagctgaac atcgttttta ctatttgaaa
     4381 gaattaattg atcaagttct atttgttaaa aatagaactg taaaaactac aactattcag
     4441 ttgttaaaaa ctgaaaacaa taacgcatta aggaaatttg acatttttaa tagttcgatt
     4501 gaagttccct atatcgaaaa ggtaagtgca gatgtattaa aagttgaaga aattacttat
     4561 gaaaatattc taaaagacat aaattttgat gtcaaagttg gagatgttat tggtttggta
     4621 gggaaaaacg gtgtggggaa aacaacctta ctaagaatac tcatgaagat tattcgccct
     4681 accaaaggaa agataatcga aaataaaaaa aatttgtcat cgccgttttt agtaatgcaa
     4741 gaaatggatt accaattttt cacagaatca gtgaggagcg agttagccct ggggaatgaa
     4801 atagttagta aagatcagca agaaaaaatt ttaaaaaaaa tggaacttta taaaatgaaa
     4861 gatcaattac cgtttgattt atccggtgga gaaaaacaaa gattattggt ttctatagct
     4921 tcattgtcaa aaactaattt atttctattt gatgaaccta caagtgggtt ggattatatc
     4981 aatatggaaa ggattgctga ccttattaaa gacttaaaag aaaagggtgc agtagttata
     5041 gccactcatg atccggaatt tctttataaa acatgcaata gaattattta tttaaaaaat
     5101 ggtggaataa aaaaagatat aaaacttaga gtagaagatt caactttgat agaacagatt
     5161 tttaatgaca taacgaaata gaattgagga gaatatatat gaaaacaaaa gattatattt
     5221 ttattggttt agctacagtt atttccctag taatttactt tttttcaata atggttagta
     5281 gtattggtgg ggcgtttggt cacagcatat ccccagggat ttttggatta ttatctggaa
     5341 tcatatttgt ttatattagc tataactacc ctagaaaagg aatttttact atttacacaa
     5401 ttgttttatt gttatttttt acgttaatgg gcggggcgta cttaccttgg tttatcagtt
     5461 cgattagtat ggcgatctta gctgatatta ttctatctgt atttggatat gatcgagcaa
     5521 ttcctcaagt tgtgtcttgg gttctaatgc aactaggcag tgctgccgga cagtggattc
     5581 ccatatggtt ctttacagat cgttttcgtc aagactggat agatagagga caatctgctg
     5641 caacaatgga tgcaatgatc cactacgcgg tgggtatatg gggaattatt tcagtgttag
     5701 ttgtagcaag tttatctatg attggtgtat tgattggaag aaaagtctta aaaaaataca
     5761 aaaaatagaa cgtagtttac cttctatctg tttgtacatc tctaatttac gctattacgg
     5821 aaagcattaa cagttgtaaa cgaataagag aagaaattga atgcggggga ggaaaaaatg
     5881 aaagtataca aaaaattatt tagttatgtc cctaaaatga aatactacgg atggttagcc
     5941 actttatttt ctgatttttc tgtcgtatta acagtctatg gatattacag tatttacaaa
     6001 tttcttcagt ctctaattat tgtaggagat gaatatttag ctaagagtta tgcggttcaa
     6061 actgttgctt ggttaacttt aggagcttta ttttatattt tttctggctt attttctcat
     6121 atccttgggt ttcgcttaga gactaatttg agaaaaaagg gaattagcgg tttaacagaa
     6181 gcaagttttc gtttttttga tttaaattct tcgggatata ttcgaaagac aattgatgac
     6241 aacgcggcta aaacacatat ggcaattgct cacttgattc cagatagtgc tcaagccata
     6301 gtaacacctg ttttatcagt tgccttaggc tttttcatta actttaaaat tggattggtt
     6361 ctaatcgcca tgttagtaat tggtgtattc ttgttaaaga aaatgacaga gaatacaaat
     6421 tttattcaaa aatatcaaga atcgttagat gtgttaagct ctgaaacggt agaatatatc
     6481 cgcggaattc aagttataaa gatatttggt gctaaagtaa catcatttaa agccttgaat
     6541 aaagcaatta acgattatgc taagtttgca tataagtatt ctttgagtgg gaaaacacct
     6601 tttgttcttt ttcaatggct attttttggc atagtttgca ttttgatagt tcctataacc
     6661 ttttttataa cttctcttac cactcccaag atcttagctg ttgacttgtt gatgttgttt
     6721 tttttaagtg gaattatttt tgtttctttc atgagaataa tgtatgtaag tatgcacttg
     6781 tttgaagcaa gatatgcagt cgaaacacta gactcccttt atttagaaat gaagcaagac
     6841 caactaaaat atgggaacga gacacagatt aaaaattgtg acattgcatt tgaaaatgtc
     6901 agcttttcat acaaagaaga gtgtgtttta gaaaatttca acttagtttt agaacaaaaa
     6961 agaatttatg cattagtagg aaaatcagga agcggaaaga gtacgatagc taaactaatt
     7021 tcaggtttct acaatgtgga taagggacag attaaaattg gtggtaagcc tttaaatcac
     7081 tattcaaaag acacaattat taacacaatt gcttttgtct ttcaagatac gaaactattc
     7141 aatcagagta tttacgataa cgtttctata gcaaatcctc aagcgccagc aagtaaagta
     7201 tttgacgcgc taagattagc cggttgcgaa tcgattttag aaaaatttcc cgaaagagag
     7261 cataccttaa ttggtagtaa aggagtttat ctgtcaggag gagaaaaaca acgtatagct
     7321 attgccagag caattttaaa agatgcaaag attgttatta tggatgaagc cagtgcatct
     7381 attgatccag ataatgagta tgaactacaa aaggcttttc aatatttgat gaaagaaaaa
     7441 acagttatta tgatagctca tcgattatcc agcattaaat ctgtagatga aattcttgtc
     7501 ttgtcagaag gaaaaatagt agaacgtgga aatcataatg aattaatggc taaacatcga
     7561 gtgtataaac aattggtcac taattatgag aatgcaaatg attggaggct tgacaatgaa
     7621 aaatttttat aaaaaaaaat ttgctttaac tgatcagggc gcagaagctt taactaaagc
     7681 ttctatttct agtttttttg tatactgcat taatatggta ccagcattca ttataatgat
     7741 gctgatagac gaattagttt tagaaaatgc aaagccccgt tggctttatt ttgcagtatc
     7801 gtttgttact ttgcttttca tgtattggtt gttagatagg gagtatgaaa acttatataa
     7861 tagtacttat aaagaaagtg cgcatttaag agtgcaaatt gcagacgatt tgtcaaattt
     7921 accattatcc tatttttcaa aacataattt atcagattta tctcaaacta tcatgtctga
     7981 cgttgaaggt attgagcatg cgatgagtca tgcaatacct aaagccggcg gtatggctct
     8041 gtttttccct tttatttcag tgatgctttt ggttggtaat gtcaaaatgg gattagctgt
     8101 tattttgcca acgttattta gttttgtctt aatcttgtta tcaaagaaat cccaaacgaa
     8161 agccaatact aaatattacg atactttgag agaaaactcg gaagaatttc aagaaactat
     8221 tgaattgcag caagagatta atagctttaa tctatctaaa aaagttcaag acagactttt
     8281 caaaaaaatg gaagagagtg aaaggattca tttaaaggta gaattaagta ctttttcagt
     8341 catggcctta tcctctattt tctcatatgt tagtttagca gtagtcattc tagtaggtgt
     8401 tcacttactg ttaacgggtg aagtgactat actctacgtc gttggttact tactagccgc
     8461 aataaaaata aaggattcct tcgattctat gaaagaagca gtgcttgaaa tattttattt
     8521 agctcctaaa atacagcgaa ttagagctat gaaggaaacc agtatccaag agggatcaga
     8581 tagtcctctg aaatcttttg acattgagtt gcgagatgtc tctttctcat atgataacaa
     8641 taccccaatt ttagatcata tctcttttac ggctaaacaa ggagaagtga ctgcgttagt
     8701 aggtgctagt ggttccggga aaactagtat cttgaaatta gtgtctagac tgtatgatta
     8761 tgatgaaggc tgtattttaa ttgatgggta tgatattaaa cgtgtatctc cagcttcttt
     8821 gtttagcaaa atcgctattg tttttcaaga ggtaactttg tttaatacaa gtattttgga
     8881 aaatatacgt attggaaata gtcaagcgtc agatgaggaa gtgaaaaaag cagctcgttt
     8941 agctaactgc gaagacttta ttgaaaaact acctgacggt tatcatacat tggtcggaga
     9001 aaacggaagt tcactttctg gaggagagcg acaacgccta tccatagcac gggctttttt
     9061 gaaaaatgcg ccaattttaa ttttagatga aattactgcc agtttagatg cggaaaatga
     9121 aaaacgtatt caggaaagtt taaatcgttt aatacaagat aagacagtac taattatatc
     9181 gcatcgcttg aagtctattg aaaaggtaaa taaaattgta gtgatggatc aaggaaaact
     9241 agttgatcaa ggtactcata atgagttgta tcgaaggtca gaaatataca aaaatctcat
     9301 aaagaaaact aaactatctg agaaattcgt ctatgaaaaa gaagctcaat cacgatgatg
     9361 aaataggctt taaattaacc tacaattttt gggatatagt tataattctt tttcaaaaag
     9421 aataatttta ttaaacagca tctaattttg aatacacgaa agaatcagta tgattgaatt
     9481 agttcactta atgtctattc ttataatata aggaataatc aaagttttaa aaaattggcg
     9541 ataaaccagt taaacataaa agattgaata aaaagttata gtttctttca tattgccgtt
     9601 ttaagtagag gaaaagctac ttaaaacggt atttgtgttt gattggacta ataaaagtga
     9661 attcttattt ttcagagcct aaactgcata ttcttttaaa tgatttgatt atctctatgt
     9721 accgataaat tcgttttcaa atagttatct attcatatga gttttatttc atgttattta
     9781 ttgttgacaa gagcaactct tgttggtaaa gtatcagtgt caaaacgtaa cgattacgat
     9841 ttgaggtgtc taaatcaaaa taaaaggagt ataaaggtat atggcaaaaa agtcgaaaat
     9901 tgctaaagca aagaaacaaa tggcgatgat tgaaaagtat gcagataaac gtcaggaatt
     9961 aaaagccgca ggagatcgca ccgctctcgc taaattgcca agagattcaa atccgaatcg
    10021 tctgaggctt cgtgatcaga cggatggtcg tccaagaggg tatatgcgaa agttcggtat
    10081 gtcccgtatt aagtttagag aacttgccca tcaagggttg attcctggag taaaaaaagc
    10141 aagttggtaa aaggaggaaa tatcatggca gtaccagcaa gaaaaacatc taaggcgaag
    10201 aaacggttaa gaagaactca tcaaactgta gtaaaaccag aaatttcatt tgacgaagcg
    10261 aatggtgatt atagacgtag ccatcatgta tctttaaaag ggtactataa tggaaagaaa
    10321 gtaattaaag gagcttcaaa atagtttaat atataacttt taggagggaa tcaaaatgga
    10381 aattatttac ccacctttag ttgaagaagg attaaagtat tatcttgaaa cgacccagca
    10441 atcgctagat aaatgcactt tttatcgttc gatggtagag agaggaatta ttactgaaac
    10501 gggtttaccg acccaacagg caattgaaaa tggattagtc aaagattact atgaggacca
    10561 aggcttatca tttgatgatt ttttaagaat ctatccaatt tttgaagagt atgacgagga
    10621 gttatttcaa tgtatcgatg gttattggga gatacctgtt gatatgaaag aaaatttagt
    10681 ttcacaattg gaatctggcg agttaacttt tgaagatgca caacaaattc aagcatatct
    10741 tgaagatcga taagtattga aggaggaaga tttatgcgtc aaaatattat tttggaatgt
    10801 gtcgaaactg gagaacgtct gtatctcacc agcaaaaata aacggaataa ccctgaacgg
    10861 ttagaattaa aaaagtattc gccaaaattg cgcagacggg caatttttaa agaagtgaaa
    10921 tagctaagtg gtaaaaaggt gacaaaatgg gcataccagt tacaatcgtt tctgggtttt
    10981 taggggctgg aaaaacaacg ctaatcaatc aagccttgca agtctcaccc taccccaggg
    11041 aagaaattat tataattgaa aatgagtttg gtgaagttgg gattgatcac aaattattag
    11101 ttcatagcga ggaacgggtg ttacaactaa ataatggatg tatgtgttgc agtcttcgca
    11161 gtgatttatt agcaatattg atttctttac tggaaacaat agaagaacat caacaaccaa
    11221 tttcacaaat catcattgaa actacaggta tagcagatcc ccaaccaatc attcaaacac
    11281 ttttaacagc gcctcaacta agaggaagag tatatatcga tagtttattg actgttattg
    11341 atagtgacag ttttgaactt attgaaagag aaccacaagc ccttaagcaa cttgtcatgg
    11401 cagatcgcat ttttgtgtct agaaaacaaa acttgaattt atctgcacta aaaaaattac
    11461 agagagaaat caaaagtatt aaccctttat ccgatattcg aatgttcaca catagtgaaa
    11521 cgattcaaaa aaaggatttt tataatttga aaaaatttaa tcatccctta gtttttgaaa
    11581 gtgattcatc agaaaatcac tataatggca aatactatca tcaacaccat caagtacatg
    11641 agtttaaatc aattctctta acttcagatc aagacataaa aaaagatttt ttactccaat
    11701 ggattgactg gctgatttta accaaccaag ggagcctgta tcgttttaaa ggattgattg
    11761 ctttacaaga gcaggatttt atagttgcca tgcaagaggt aaacgaacag gttaattttc
    11821 aatacaccac tcgacaaaaa gaccaaacca ctattattct aatcggaaaa atgttggatg
    11881 aagaaaggat caaacagagt tttgataaat tactggcgga aagcaaataa tgataagtag
    11941 tgattggggg taatttctaa tggagaaaac ggatatatct agtgcatatc gacgacttaa
    12001 aagcccgaat attaaaacta gaaaaagggc attaaaaatt atcaaagaac ataaacgaaa
    12061 taaaatgaag aaattagcat aattaaggaa ggaaaaagaa tgaagaaaat cagtgtagga
    12121 cttattggga tagcagctct aggattattg ggagcttgct ccagcactaa tgatgcaaaa
    12181 gtatcgaatg ataaagatgg aaaattagaa attgtaacaa cattctatcc aatgtatgat
    12241 ttcaccaaaa acatcgtcgg cgatgaagcg aacgtggatt taatggttcc agcgggatca
    12301 gaacctcatg actatgagcc ctcagctaag gatatggcaa aagctcatga tgctgatgtt
    12361 tttgtatatc ataacgaaaa catggaatca tgggtaccaa aagctaaaga aagttggaag
    12421 aaagctgggc ctaatgtagt agaaggaaca aaagacatga ttttattgcc aggtagtgaa
    12481 gaagaagatc atgatcacgg agaagaagat caccatcatg aactagatcc tcatacgtgg
    12541 gtttcaccca aaatggcaat taaggaagtt tcaaatatca aggatcagtt agttaaattg
    12601 tatccgaaaa aagcaaaagt atttgagaca aatgctgaaa agtatttgac taaactgaaa
    12661 cggttggatg ctgactatac cactagtctt aaagaagcga aacaaaaaag ttttgtgacg
    12721 caacacgcag cctttggata tttagctttg gattatggat tgaaacaagt tcctattgct
    12781 ggactaagtc ctgaagaaga gccatcttct ggtcgattag ctgaattaaa agagtatgtt
    12841 aaaaaaaata agatcaatta tatttacttt gaaaagaatg ctaatgataa aattgcaaaa
    12901 actttggcca acgaagctgg gataaaattg gaagtactga atcctcttga aagtcttaca
    12961 aaagaacaaa tggataatgg tgaagattat gtttcagtaa tggaagacaa tctaaaagcg
    13021 ttagaaaaaa caactatggt tgctggtgaa gaggtagttc cagaaaaaga agcgaaggat
    13081 gaaaagacag ttgctaatgg gtactttaaa gatgccgatg tgaaggatcg cgaattgagt
    13141 gattatacag gcgaatggca atctgtttat ccgttgttaa aagatggaat tttggatgaa
    13201 gttttcgatt acaaagcaaa aatcaataaa gacatgacag ctgccgagta caaagattat
    13261 tatactactg gctataagac agatattgat actatcaaca ttaaagacaa caccattgat
    13321 tttgtagtca acggtgaaca tcatcaatac acatacaaat atgttggata caaaattttg
    13381 aattatgaaa aaggaaaccg tggtgttcgt tttaattttg aaactgatga tgcaggtgct
    13441 ggtcgtttta aatatattca atttagtgat catggaattg caccaagtaa ggcagagcat
    13501 ttccatattt tctttggtgg agaaagtcaa gaaaaactct ataatgaatt gcataattgg
    13561 cctactttct atccagcttc attgtctaaa catgaaattg ctcaagaaat gatggctcat
    13621 taaaattcaa tttttggagg aaatacatgg taagaaaagt attattgtct atggattcca
    13681 agaatattga tgcttatcgg cgttatcgat ttgcaaagca aatgagatta aatgggagta
    13741 cattagctga tattgctgca actttacatg ttagtattga cacagttcat agagtattaa
    13801 aacgggatcc tgattgttgt tttatcaagg tcaatactgg aagaagtaga cgtttagcaa
    13861 aacggcataa tagcttggcc aattaattga taataccaga gtagatcatt tttcccttat
    13921 ttggatttga tctgcttttt attatgtctt gaattgtcaa atcaagcgca acactttatc
    13981 aaagaagact tcataaggtg ttctccaatc taaacacttt ctaggtctgt tattcagttt
    14041 ttcaatcatc tgatttatcg ttgagttatc taccgtagct atctctttcg attttggcaa
    14101 gtattctcga atgagtctat tcgtatttta atttgttcat tgttgccaag ggcatgagga
    14161 tctggaaaat aaaagggcat attattcaat gcttctgtaa ctgcgaaatg attggagaat
    14221 tcttttcctc tatctggagt gatcgttttg accgcctcat ttggaatact gcttaaaagt
    14281 tcaatcattt tctcgctcac ataagcggct ttctttctgg ggaccttctt tcctgctaaa
    14341 aggaagcatg attttctgtc tgtcaaagtc actaaacaag taccaccagt tttgccagct
    14401 acaatatcgg ctttccaatg accaaaatca cttctatcat ctgcggattt tggacggcca
    14461 tggatcgaat gagtaaggca aatctttcca cgagactcga catgattttt tgtatgtctt
    14521 gtttttcctc gatggtgcaa tgaacggatc aggcctttat tgccgt
//
LOCUS       DAFBSV010000072        14409 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.073, whole genome shotgun sequence.
ACCESSION   DAFBSV010000072 DAFBSV010000000
VERSION     DAFBSV010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14409
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.073"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(<1..1416)
                     /gene="nhaC"
                     /locus_tag="LLB18_002100"
     CDS             complement(<1..1416)
                     /gene="nhaC"
                     /locus_tag="LLB18_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBK5245090.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(1819..3042)
                     /locus_tag="LLB18_002101"
     CDS             complement(1819..3042)
                     /locus_tag="LLB18_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBK5245091.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(3073..3912)
                     /locus_tag="LLB18_002102"
     CDS             complement(3073..3912)
                     /locus_tag="LLB18_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBK5245092.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(3929..4609)
                     /locus_tag="LLB18_002103"
     CDS             complement(3929..4609)
                     /locus_tag="LLB18_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5245093.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(4611..5684)
                     /locus_tag="LLB18_002104"
     CDS             complement(4611..5684)
                     /locus_tag="LLB18_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK5245094.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(5740..5978)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(6021..6254)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(6331..7002)
                     /locus_tag="LLB18_002105"
     CDS             complement(6331..7002)
                     /locus_tag="LLB18_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBK5245095.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(7089..9767)
                     /gene="mgtA"
                     /locus_tag="LLB18_002106"
     CDS             complement(7089..9767)
                     /gene="mgtA"
                     /locus_tag="LLB18_002106"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBK5245096.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            10426..10863
                     /gene="ndk"
                     /locus_tag="LLB18_002107"
     CDS             10426..10863
                     /gene="ndk"
                     /locus_tag="LLB18_002107"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HBK5245097.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(10885..11751)
                     /locus_tag="LLB18_002108"
     CDS             complement(10885..11751)
                     /locus_tag="LLB18_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBK5245098.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(11911..14004)
                     /locus_tag="LLB18_002109"
     CDS             complement(11911..14004)
                     /locus_tag="LLB18_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBK5245099.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
BASE COUNT         4180 a         3089 c         2450 g         4690 t
ORIGIN      
        1 ttgttctaat tgcgctgtct tgcttactgc ttcttgcggt ttcacaaatt tttttgagat
       61 tccccaacct gtgaaggcac tgaccatcga aaacacagga gaaagcaaac tgaaaaatac
      121 gaatggcaag taagtgagtg taggaatacc aaatgtactt gctacgaaac ttccggcaat
      181 tccccaaggc actaagtagt tgattactgt tccaccatct tctagcgttc tacctaatac
      241 agttggatca aatcctgctt tttcataagt ttctttaaat gcattaccag gcagaataac
      301 agataggaat tgttcaccaa taaaaatatt tactccgata cttgtcatca atgttgtaaa
      361 aatcaaattt ggtgtgttcg tcatctttct tgatactcgt tccatcacgg ttgagatcaa
      421 gccaaattcg atcaacaatc cacctaatga caaagttaga ataatcaatg acacagtagg
      481 catcatactt tcgattcctc cgcggctaag cagtgaatcg atttgttggt ttccagtatt
      541 tgaaacaaac cctgattcga tgaccccagc caacttcgtt aaggaagttt gtgggttttg
      601 aataaaaatc attcctactg ctacagcgat attcaacaaa atcgttaaaa ttgccggcac
      661 ctttttccat gcacacagta acattaaaaa taaaggaatc agtgaccaga ttgaaatagt
      721 aaagtttgct tctagaacat cagtcacttc acgaatagat gaaagacttg cggctttact
      781 tgtgtgtcct aaaatcatga ataaaaagaa agaaacaaca aatgccggga cagttgacca
      841 catcatatgc ttgatgtgtt tgaacaaatc ggcatcaaca atagctgctg ctagatttgt
      901 tgattcggat aatggagaca tcttatctcc aaaaacggca cctgaaacaa tagctccaac
      961 aaccagcgct ggatttaagc ctagtgttgt cccaataccg aaaaatgcaa tcccaatcgt
     1021 tgacataaca gtaaaggcac tccctacagc gctacctacg attgcacaca caacaaatac
     1081 agaagggaca aaccactgga cactgatcaa tttgaaccca atgaccatta gagttggaat
     1141 gatccctgct tgtatccata cagcaatcaa tgaaccgact aaaataaaaa taaagattgg
     1201 gatgattcct ggtttgatgc cattgatgat tccttcgtgc agccaatctg tcgggtatct
     1261 ttttatcact gcatacaaca tgaccattcc gatcgctgct aagatcgtga tattaggtga
     1321 gacctttaat ccgacaacgc caatcgcaat gcctaaaaca ataaccatta atacaagtgt
     1381 tgcttctaaa aaacttggtg ttcctttttt tcccatgata atctctcctt ttttagttgt
     1441 tcttatgttc taaaaaagtt aagatatcgg attactccgc cgcaattcat ccgcgattcc
     1501 tcctttataa aaataaaaag acctgtttta aactaaggac gaatgactcc gcggtaccac
     1561 cttaattaaa aacagatctg tttttcactt tcaaactttt attcaaatgt atggactttc
     1621 catgtaattc gtcaattagg cttgatcggt tcacagcgac caccgacttt ctgaacaaaa
     1681 cacctaaccg ctactgcgtg aaaagttgac ttgtacgaag tttaccttcc ataagatcat
     1741 ttgtcaatga aaaagaaaat attttttcat ttttctgaaa attattttta taactttcac
     1801 acacaagttt attttttact agaaagtagc gccctcttgt ttttttcttg ctactatttc
     1861 ttgatgttct tgcttgattc tttctaatag ctttggctct ttcaacagat caagagctgt
     1921 attggcgagt agttctgctg caatcgcaat agaagcaagg cctttgtcac ttttagcagc
     1981 agctttgaat tcttctgtgt gtccggcaat atatgtctca gagattgcta ccgtaggctg
     2041 gattgttggt atgacttggc tgacatttcc tacatcagaa gaaccgagac ttgttctttg
     2101 ttccgtttct atttcttcat ctggaacacc tgcttctttt gcatgctgga agaataagtc
     2161 atcaaaagaa ggagtaacga tgacatcatc aactgcattt tggaacaatc caaactcaaa
     2221 agtcgtgccc gtacttatcg cagcacctcg tacgatattt tccacttttt catatacttt
     2281 atctaatgtt tgccgatttc ctgcacgtaa atagaaacgt ccagcagcgt aatctggaat
     2341 gacgttggca gctactcctc cgtctgtaat gatcccatgg atattgacat cttttggcaa
     2401 ttgcaagcgt agagcgttga ttccattaaa cacttggatc aatgcttcca aagcatttac
     2461 tcctttttca ggtgctgctg ctgcatggga agcgacaccg taaaatttga tgtcgactgg
     2521 atcattcgct aaagattctg tcgttttccc ataacgaaaa gctggatgga cgcataacgc
     2581 tacatcgaca tcctcaaaaa aaccttctcg aacaaagctg cctttagctg atccgttctc
     2641 gcccccttct tcccctgggg tgccatatac acggatttct ccaccagttt catcaatgaa
     2701 ttgcttcact atgctggcgg ctaatacgga gtaagtacca aacaaattat gcccgcatgc
     2761 atgaccaata cctggtaaag catcgaattc tgccaaaaag gcaattgtgg gaccgggttt
     2821 attggaaata taacgtgcat caaaggctgt tcggtgtcca gctacttctt tttctaccca
     2881 aaacctttct ttttctaatt gtttaatcaa cgctgctgag gaataaaact catagttact
     2941 tacttcagga tgttcgtgga tatctagagc aagtgcttga tattctggta aacgatattg
     3001 gattagatcc ttcaattggt ttgttgagat tgttgttgtc ataaaaaatt cctcctatgc
     3061 tagtcatttt tcttattttc tcccgaatgt ttcccatgca ggcacgcttg atccttttga
     3121 tgttttctcg attactttga ctgtgtcttc tgtttgataa gcgtctacta ttttttgata
     3181 cgttttattg ttttcatctt cttttcttgc aacgatgata ttcacataag gacgtgcatg
     3241 gtcatccact ggttctaaga agatggcatc agaagcagga ttaaatccag catctacagc
     3301 tacaccgcta ttgatcactg aaatgtctac atctgacaaa gcacgtgctg tttgggaagc
     3361 atctaattca gaaatgtcta gattttttct attctcggta atatcagaaa cagtgggcgc
     3421 ttgtcctttt gccttatcca ctttgatcaa tccagcagtt tgcaataaca gaagagctct
     3481 gccgccattt gtaacatcat tagggattgc tacttttgct ccgtctttga tatcagctac
     3541 atccttcaaa gtgttagaat aaattcccag cggtgcattg acagtatttc cgatcgatac
     3601 taaatcagtt ccgtgttctt tattgtaatt gtctaaaaag aattgatgtt ggaaagaatt
     3661 caaatcaatc gatccatctg ctaaagccac atttggttga ttgtaatctg taaatttcac
     3721 gtattccaaa ttaatgttct cctttttcaa acggtctttc acgttgtccc atacatctgt
     3781 atcttctcca ataatcccta gttttacgat agtttctttt ttgtcagttg tatctgcttt
     3841 tccttggcta caccctgcca accaaataat tgctacaaat gtaatgacta caaaacgaat
     3901 aatttttttc attttttctc ctccactttc aatgtgtaat ttttttaatc agttgattac
     3961 tgataaattg acttaaaaaa actaagatta gaatcaataa tgtagccaca atcgttacat
     4021 ctgtttggaa tcgattatac cctctcgata tagcaagatt ccctaatccg cctgcaccta
     4081 ctgctccagc catggtagtc agtccgatca cgttgatgat agtcaacgcc gagacccgaa
     4141 tgataccagg caaaccttct aacaaataca cacgtaaaat gataccgatt ggactggttc
     4201 ccatcgcttc tgccgcttcg atcaccccag gatcaacttc tagcagtgcg ttctcgattt
     4261 gacgagcaaa aaacggaaca actccaaaaa tcaatggcac taaagctgct ttcgcaccaa
     4321 tcgtcgttcc aactaagaaa cgagtagtca atgctaaaag agaaagcaag ataatgaaag
     4381 ggatggaacg aatgatattg atcagcttat caagtatttc aaatagcaga cggttagcta
     4441 gtaatccatt agggcgtgtc actactaacg tcacacctaa gatgattcca atcatcccgc
     4501 caatgaatgc tgtccaaaaa gacatatata gtgtttgctt cgtcgcttcg acaaattcat
     4561 ccggaatcaa ataaacattg ggcaaatatg ttttaaagaa atcagtcatt ttatcttcct
     4621 ccttcgatca ctttgatacg actatctaaa tcgttttttt gtaaaatatt tatttttaca
     4681 ccagatttga tcaaataatc caatgctttt ttccgctgtt tggtttctcc agctaaagta
     4741 acgatcaaac tccctaacgg cgtttcttgt aataactcta cattgccata taaaatattc
     4801 gctgttactt gatatttgct gtacagatga gcgattagag gttcgttcgt ctgatttcca
     4861 atataactta attccaccag ccatttattg gcgatctgat cggcaaaagc agaatgggca
     4921 atgatcgttt ctaatgcttg gtcaagatga gtagctgttc gaataaaatc tttggtcaat
     4981 tcttcttcag gattgctgaa gatctggatg ctgctacctt tttcaacgat tcttccatct
     5041 tccataaccg ctaccttgtt gcagatttct ttgacaactt gcatctcatg agtgatcagg
     5101 acgattgtta aacctaactg gcgattcaat ttttttaaca atgcaaggat ctgaagggtc
     5161 gttttcggat caagtgcact ggttgcttca tcacataata ataccttagg ttcattcgcc
     5221 aaagctcgtg cgattgctac tcgttgtttt tgtccccccg acagttgttt aggataagca
     5281 gatgcttttt cttccaaacc gacaagttcc agtagttcat tcactttttg acgacgttcc
     5341 tgtttcgatt ttccagaata ctttaaagaa aaatcaacgt tgtcaaaaat agttcggctt
     5401 tccattagat tgaaatgctg aaagatcata ccgatggcct ttctttcttt tcgcaattct
     5461 ttgggagaga gctgactcag attcgtctga ttgacaatga cttctcctgc tgttggtttc
     5521 tgcagcaaat tcatcacacg aactaacgta cttttccctg cacctgagta accgacgatt
     5581 ccataaacat cgcctttttc aatcgttaaa tctacagaat ctactgcctg tatctctttt
     5641 tctttttgtt tgaaacatac agaaacatct cgcaattcaa tcattaaaat tcctccttat
     5701 ctaaaaaaag cgtcctcaag aaaatgaaaa tgtcattttc ttgaggacgc ttttttgcgt
     5761 gttaccacct catgttcaag ctgtgttcac acacaactcc tcttcaagta cgatcatact
     5821 ctagcaagat atcggtcgca gccgtcatcg ccttacatct atgctcggga tgaattgctc
     5881 gatggccatt ttccaatagt cgttccttgc ttcttctcag ctaccgaagc tctctgtcaa
     5941 aggttcttct atcgtactta ccatttcaat gcaaataata ttcaaaaaaa aagtcctttt
     6001 actaacataa actatgtcag taaaaggacg acgtatcgcg gtaccacctt ttttcggaag
     6061 tttccttccc tcaagcccaa catctcaaaa agagagattg gcgttcgttt taacggtcga
     6121 acagttccga atttgcctac ttatcgacaa attattctcc aaggccattt tcagcttttc
     6181 ttacttgact cttctcacca gccagagcct ctctgcaaag tttccaaact tactttcctt
     6241 ttcaacgaaa tcgatatttt gttgttggga ttaatctaca tgaggaaaac tgaaaagtca
     6301 agtacgaaat tcaaattatt ttttctatat ttatttttct gtttttttat ttaacatttc
     6361 aataacagtt cgaagatctt ttccttccgc aagaagtttc aatttttcct tttcttcgac
     6421 ggtataattt cggacaaaac tggaatcagg tatcaaaaca acgcctaatc ctgctcgtga
     6481 agcagctgtt gctcctacta aagaatcttc cactgcaaag gctgaactag cttctaatcc
     6541 tgttcgttcc aaagctgtca gataaggaat cggtgaaggc ttgttctccg acacttcgtc
     6601 tccgaatgta aacgtgtcca agtaatcagc taatttaaag tgatccaaga tatctgttgc
     6661 tcttttcgta acagtggtcg tagcaatgcc tagtttcata tgacgttctt ttaagtctgc
     6721 caatatttct tttgcatatg gttttaagtg gatggctccg cttgtcagct gttgataaaa
     6781 atattcttca cgcttcgctc ggacttcctg tactttttca gggctacctg ctgctttcac
     6841 taaaatatca aaactttgtt tccagttttt tccgccccaa gcgtcaacga tttcttttgg
     6901 gatatggata tcaaattgct gaaatcccca aagccagcca tcacgatacg ttttttctgt
     6961 gtcaactaac aaaccatcta aatcaaatat tgcacctttc atctatacat taatcctttc
     7021 caaaacaata cacatagttt agcacgactg gtccaaaaag aacagaagca aagaaccagc
     7081 cttctcgttt ataagagttc ttggaatcga cggatataga ttttcttcac agctgtcaca
     7141 agcgccagat aagcgatgac tgtagcaaat aaccataacc agtaattgcc aggaagtggc
     7201 atcaagccta attcagcacc aaaacttgta aaaggaagga cagaaccgac aataattcct
     7261 aatgtagtga taacaaacat ggcaaatgtt gcgttgcttt ggataaatgg tactttcggt
     7321 gtacgcagtg catggagcac taaggtttgt gtccatagtg attcgacaaa ccatcctgca
     7381 tggaataatg cgatgaaaat cactcgctgt gaactatcca atgtatggaa acttccgccc
     7441 actacagcag gacaaataac aaaatacatc aacaagtaag tagtaatatc aaatatcgaa
     7501 cttgttggac caaagtaaac catgaattcc ccaatactag atgcattcca tttttttggc
     7561 tcgtccaaat attctttatc catccgatcc catggcaagg aaatgcagga aacatcatag
     7621 atcagattca aaaacaaaag ttgtaaaggc agcattggta aaaatggcag gaacgtactt
     7681 gcaatcagca cggaaaacat attgccaaaa ttagaacttg ctgtagcctt gatatatttc
     7741 atgatattcc caaaagtttc tcgtccagaa agaaggcctc tttccaaaat cgtcaaatct
     7801 ttttctaaaa ggatcacgtc tgcagattct ttcgcaatat ccacagctgt atctacagaa
     7861 ataccgatat cagccacttt cattgcagga gcgtcattga taccatctcc taaaaatccg
     7921 acagtatgac catttttacg taaagctgtc gtcaaacgtg ctttttgctg aggattcaat
     7981 tttacgaata cttcatggtc ttcagctact tgtgctaatt catgatcact catttccgag
     8041 attttctcac cggtaaccaa ttcattgatc tctagaccta cttgacggca cactgaacgt
     8101 gtaactaatt cgttgtcccc agtcagaact tttacagcta caccatgttc tttcagagct
     8161 ttcaacgctt gtttcgttgt ttcttttggt ggatcaagga aagcaagata accaatcaaa
     8221 accatgtctg actcatcttt gactgaaaat tctccaacga cgcttggatt ggtcttttgt
     8281 gcgacaccaa tcactcgtaa gccatcttca ttaagtgact gtacttttgc aagtacggct
     8341 tcttttcgtt cttttgttaa tggtgtaaca gtaccgccaa gatcaataaa tttagaaatg
     8401 ttcagcattt cttcaatcgc gccttttgtg atcatttgtg ttttaccagc tggatcagca
     8461 accacaacac tcatacgacg acgttcaaaa tcaaaaggaa tttcatccac tttttgataa
     8521 ttgatcttat ctgtatctaa agtttctgtt gcttcatcaa tgatagccac atctaacaaa
     8581 tttttcagcc ctgtttgata gtagctattt agatacgcat ggcgcaaaac acgatcatct
     8641 tcatttcctt cacaatccat atgatattca agaatgattt tatcttgtgt caatgtcccc
     8701 gttttatccg tacataacac atcgattgca ccaaagttct ggatggcatt caaatttttg
     8761 atcactgttc cttttttggc catcacactt gctcctttga ccaaattcgt cgtaacgatc
     8821 attggaagca tttcaggtgt tagaccaact gctacagata gtccaaaaag aaaagcttct
     8881 agccaatccc cttttgtaag cccattgatg acgataactg ctggagccat caatgacata
     8941 aatttgatca gtagcatgga tgttttatgg atgcctaatt caaagcttga ttgaattggt
     9001 ttttcagata gcgtttctgc tacatgacca aatagtgttt catttccaac agaaacaatg
     9061 attccttccg cacttccact gatgacatta cttcccataa agacaagatt ttcgtaactt
     9121 gtttcgcttt gctgatcgtc ttcacatact ttcgcatgct tttctactgg atagctttcc
     9181 cctgtcaatg ctgcttggga aatgaataaa tcctttgcgg acaataaacg catatccgct
     9241 ggtatcatat cccctgctga aagccgaaca agatctccac agacgatttc ttccatagga
     9301 atctctgtgt actttccatt acgttttaca gctgccgtta ctttcacaag tgatttcagt
     9361 ttttcagccg cttgattgga acgtacggac tgaatcaacg tcattgtccc gctgacgata
     9421 accatagtga agataatggc tacaccgaaa agatctttat ctccaggagc tgctaataca
     9481 tattccgtga tgaatgaaat aattcctaat gcgatcaaca ctaatgtaaa tggcgtgatg
     9541 tatgctttca atatttctac aatgaatggt gtttttttgc catatgaaat cgcattttca
     9601 ccgtaatttt ctcttgaacg ttcgatttgt tcttctgtca atccatttgc tgatgcatgg
     9661 aatagttcaa ataattcttg tttcgttttt ccagcaaaag ctgcatagat tttttgtgta
     9721 tctttctttt tttccatctc aatctctcct ttgtgtccaa aagacagctg ttctcgctgc
     9781 ttttggtctt tagctattca tcggatcgat agagaaaaaa ctgaaagggg ctgagaacag
     9841 atagataata gccctggcct ttcctctaga tccttgtttt tcgaatgact gtcatccatt
     9901 tgttctcatc tcctttacta agtaatttta attcatgact tccaatcatt tttcgaatag
     9961 ttatttttcc aattagacca cctccttttt atttttcacc gatggggatt tgcggcaaca
    10021 aaaaaacctc tcgccaaata ctcagcgaaa ggtttgaaaa agcatattaa aaaaagcttc
    10081 tcagatctca tcgttgagtt ttgacactgt acaacgtaaa aagcagatac ctgcttttag
    10141 ctaccttatg aaaagcctta tctcgacaat tcctgttcta cccattggcg tctctcgacg
    10201 tttttgggca gtagcctatg tttgtatagg agcctcacct aacaaatctt attcggtttt
    10261 ccttcgttaa tataacaact aaaaaagagg atgtcaaatc aattttccat gtttttcata
    10321 ctttttttaa aatacacacg ttatattcct gtctcacgcg gttttatttg tctcattttc
    10381 cacctcccgc tataatagaa atatagtagg aaacgaggtg ctgttatgga aagaacactt
    10441 gttattatca agccagacgg cgtgagacgc catttagtcg gaagcatcat ccaacgtttt
    10501 gaagcaaagg gactggccat tgctgaaatg aagtttgaaa ctatgactcc tgaattagca
    10561 aaagaacatt atcagcactt gactgagcgc agtttttttg atgaactgat cgattacatg
    10621 acttccggtc ctgtcgttta tcttgtgctg gtcggcgagg aagtgatcga tatcgtccgt
    10681 aagatggttg gagcaacaaa agctgccgat gctgttccag gtacgatccg aggagactac
    10741 gcgctgccgg ggactgaaaa catcattcac gcttctgatt cccgtgatgc tgcggtaaaa
    10801 gagatcgccc gctttttccc gccattcgat ataaacaaac cgtctgaaaa agcggcgaag
    10861 tgatacaaat tctaaactgc tggtctagtt gctgggttca gcaatggcca gcagtttttt
    10921 ctctaaggac ctccgttgat tctttcctaa catatattcg agcactgtga agaattcttg
    10981 gtagtctttc gtcttttctt cccctaaagc agcagaaatc aatctttgat aataatctgc
    11041 catcaatgtt tcatagatca ctgtacttct ttctttatgt gctaagctcc gtttcatatc
    11101 ttcattcaca ctacgtgcct ttttcaaccg accattttct atataaaacg aagtcaggtt
    11161 cattaaaaaa gtaaagagat actgctcatg attgttcaac tgtgctaatc gtcgcattct
    11221 ttttttgatt ttcaaataat tgttctcaat gaaccgatca ctgaatatcc aaggaaaatc
    11281 agctagaata gatagttcaa attgaccata gtctggtatc tgcatcaagt attcttcaat
    11341 gattcggcat tcataacgta aaaattcaaa ttctgtctca gatacttctg ttttttcgac
    11401 catgtgaaga ttcaaaacca aataatacag atcttctgtt ttcttaaaat gcctacggtt
    11461 attgctgatc tctttataag gatcaaagct gtcttcttgt acccgatcta gcattcgtct
    11521 ttttttcttt aactttattg gttcatccag ctggtttcgc atccattcat attctgcaag
    11581 tgtcatgttc attcgctcta aaaatgatct caatgttaca aatgacattt ttttcactga
    11641 atttgtctca atcccgacta gagaagtctt aaaacagatt ccttccgcta attgggactg
    11701 tgtcaacttc ttgttgactc gaagtttctt gatcaattca ccatcataca taatagttct
    11761 cctttttaat ttaaattttt ccacattcaa taaatagata cgttaaaaag gaaaaataca
    11821 cgaaaaaaat aaaaaaatgt ttttttcata aaaaatacca accttcaagc attagaatgt
    11881 tgtctaacta ctgaaggttg gtttgattgt ttattgatta tttttttgct gttcaacgtc
    11941 tgttcttgtt actggatata agttggttgt tgttttatta ccattttttg aaaagacact
    12001 tgtcgaatgt tcgccttttt gcttttcgat tgcttcatta cgttccgctt catttttata
    12061 gtcatatttt ttcggatcaa tcgtctcaaa tccgtttggc acataaaacc gcaagagatt
    12121 ttcctgattc agcttatctg aaagacttaa cgcagtcttg actttttcct gatctttgga
    12181 gatttcctca tcgattcctg ctgctttcgt atcgatgatt tctcctgtct gattattgta
    12241 agcttttcct cctaggacgg tgtatttggg tgtcacaaag ttcccatttc gaaaagcaac
    12301 tacttgatca tgctgagaag ataataagtc tgtaccaaaa tgaagataat ctttatcatc
    12361 gattcccaat agatgtagta atgtcggcaa aacatcgatt tctccaccgt attcatgatt
    12421 gactgtccct ttagtataac caggcatatg gatcatcaat ggcactcgtt gcatctgtgc
    12481 gttgtcaaat tcatcccatg tatctggatc tttaccaaga gcgcttgcta aatctttatt
    12541 atctgtattc gagatcccaa aatgatcccc gtaaatcaca aagattgaat tttggtaaat
    12601 accagatttt ttcaaatacg taaaaaattg ttccaatgat tgatccagat aatgtgccgt
    12661 tcgaacataa ttatctactg tgctattgcc agtattcaaa gatggaaagt cgaaattctt
    12721 gtcatccgta taataaggcg tgtggttggt tacggaaaga aatttcgtgt aaaacggctg
    12781 ttgtagatgc tcaagatatt gggcagattc tctgaataaa tctttatcta atatcccata
    12841 acctaacgtt tcgtcggatt catcaaaata agatcgatca aagaaattgt cataacctaa
    12901 gtttttatat acatgatctc tattccaaaa actagctaca ttcccatgga aaacagcgct
    12961 tgtatagcct tgcttttgtc caaggatcgc tggtgcggct tgaaagacat tgtctgaccc
    13021 aagttctgtg aataatgagc cttgaggtaa accaaatgtg ccagtttcca acatattttc
    13081 agcatcactt gtctttccct gtcctacttc atgaaagaaa ttgtcaaagc tgatcgttgc
    13141 ttgattctgg aaaatactat ttaaaaacgg tgtgacttct tgtccgtcta ccttcatatt
    13201 aatcaaaaac tgctggaaac tttctaaatg gagaacgatc acatttttcc ctttagcgat
    13261 cccaaatgtt tcgggatttg gctctgcata atgtttcttt gtataatcta aaacttcatc
    13321 aatcccatta ctgcttgcat gcgcgcgaac actgctagtc attcctgttt tgattccgtc
    13381 ataaatagta tacgcatcga ttcctagata tttgacaata tatgaacggt caaatgttcg
    13441 ctgcagcaat tgtggacggt tggcttcgct cagcgctaga tttcctgaaa aaataagccc
    13501 tgaaagacag gtaacagcga tagccatcgg tttgccgaca gggttgcttt tgataggtat
    13561 tttcttgacc ttcaaccaaa ccagtagccc aatgaacaca gcgatatcca gccagtagat
    13621 gacatcatgg ggcttcatca aagaaaagga gcttcctgac aatccttgcg acactttcga
    13681 aaagcctaat acagatttga ctgtaatgaa atctgtgaat tcccgataaa aaataatatt
    13741 caagtacaac aaaagcgtat ttaaaatatc aatgatcaaa agaatagcta acgctggctt
    13801 tggcttttta atatacaaag aaaggccaaa aaacaataag gtagtcgcaa ttgggttgat
    13861 ccacaagata aagtactgga tcgtaccttc cacacctaat gaaaaatctg catagtaggc
    13921 aatgatcgtc ttcagccaga aaaagaaaac agctgtcaaa acgattgcta aacgattttg
    13981 gcacaatttt ttaagttgtg tcacgtatat cacttctctc tattcacatt ttttcttatt
    14041 ttgctcctga aaaatgaaaa tttcctaaaa aagttgttat cttaagattt ttttattctt
    14101 tctaaagatt attccgtcca cttttcacag cataaaaccg ctgcgatgta agcgattaaa
    14161 ctaatgaaga gataaaagtc ttgtggtgac cgcttcactc cacggtattc aaaagccagt
    14221 ttctcggtat tcgtacaaaa aaagaggctg tgacaaaatt cttgtcgcag ctccttattt
    14281 cttgatgcag gacagctttt tcacaacttc ttccttaaac ggtgttctcc tgccaactcc
    14341 tcggccacaa gtcacaatat ttataaaaca tgagaagctg ttttttgaaa ttgttccttg
    14401 tggctcaga
//
LOCUS       DAFBSV010000073        13917 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.074, whole genome shotgun sequence.
ACCESSION   DAFBSV010000073 DAFBSV010000000
VERSION     DAFBSV010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13917
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.074"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            131..505
                     /locus_tag="LLB18_002110"
     CDS             131..505
                     /locus_tag="LLB18_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBK5245100.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="LLB18_002111"
     CDS             complement(619..1248)
                     /locus_tag="LLB18_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBK5245101.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="LLB18_002112"
     tRNA            complement(1382..1454)
                     /locus_tag="LLB18_002112"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="LLB18_002113"
     tRNA            1668..1741
                     /locus_tag="LLB18_002113"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            complement(1879..2043)
                     /locus_tag="LLB18_002114"
     CDS             complement(1879..2043)
                     /locus_tag="LLB18_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245102.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2338..3666
                     /locus_tag="LLB18_002115"
     CDS             2338..3666
                     /locus_tag="LLB18_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HBK5245103.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="LLB18_002116"
     CDS             3868..4701
                     /locus_tag="LLB18_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HBK5245104.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="LLB18_002117"
     CDS             4717..5454
                     /locus_tag="LLB18_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HBK5245105.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="LLB18_002118"
     CDS             complement(5609..6577)
                     /locus_tag="LLB18_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBK5245106.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="LLB18_002119"
     CDS             6809..7642
                     /locus_tag="LLB18_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HBK5245107.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="LLB18_002120"
     CDS             7676..8515
                     /locus_tag="LLB18_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBK5245108.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="LLB18_002121"
     CDS             8541..9101
                     /locus_tag="LLB18_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBK5245109.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="LLB18_002122"
     CDS             9300..11021
                     /locus_tag="LLB18_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HBK5245110.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="LLB18_002123"
     CDS             11186..12328
                     /locus_tag="LLB18_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBK5245111.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="LLB18_002124"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="LLB18_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBK5245112.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
BASE COUNT         4750 a         2297 c         2834 g         4036 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccagca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaattattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttg
//
LOCUS       DAFBSV010000074        13856 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.075, whole genome shotgun sequence.
ACCESSION   DAFBSV010000074 DAFBSV010000000
VERSION     DAFBSV010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13856
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.075"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            394..1527
                     /locus_tag="LLB18_002125"
     CDS             394..1527
                     /locus_tag="LLB18_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HBK5245113.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            1558..1878
                     /locus_tag="LLB18_002126"
     CDS             1558..1878
                     /locus_tag="LLB18_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HBK5245114.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(1907..2371)
                     /locus_tag="LLB18_002127"
     CDS             complement(1907..2371)
                     /locus_tag="LLB18_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5245115.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(2503..3757)
                     /locus_tag="LLB18_002128"
                     /pseudo
     CDS             complement(2503..3757)
                     /locus_tag="LLB18_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(3786..4103)
                     /locus_tag="LLB18_002129"
     CDS             complement(3786..4103)
                     /locus_tag="LLB18_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBK5245116.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(4129..4449)
                     /locus_tag="LLB18_002130"
     CDS             complement(4129..4449)
                     /locus_tag="LLB18_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5245117.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(4913..6328)
                     /locus_tag="LLB18_002131"
     CDS             complement(4913..6328)
                     /locus_tag="LLB18_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBK5245118.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(6345..7661)
                     /locus_tag="LLB18_002132"
     CDS             complement(6345..7661)
                     /locus_tag="LLB18_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK5245119.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(7811..8509)
                     /locus_tag="LLB18_002133"
     CDS             complement(7811..8509)
                     /locus_tag="LLB18_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBK5245120.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(8798..9754)
                     /locus_tag="LLB18_002134"
     CDS             complement(8798..9754)
                     /locus_tag="LLB18_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBK5245121.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(9867..10700)
                     /gene="msrA"
                     /locus_tag="LLB18_002135"
     CDS             complement(9867..10700)
                     /gene="msrA"
                     /locus_tag="LLB18_002135"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBK5245122.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQGERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(10875..12503)
                     /locus_tag="LLB18_002136"
     CDS             complement(10875..12503)
                     /locus_tag="LLB18_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245123.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIRLVSKGFKNADFIAI
                     FKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNNDL
                     TTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAKLL
                     QFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFNQK
                     IISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNLPY
                     KTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGVAD
                     IKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            complement(12490..13824)
                     /locus_tag="LLB18_002137"
     CDS             complement(12490..13824)
                     /locus_tag="LLB18_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245124.1"
                     /translation="MDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYYAY
                     GLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFVVV
                     NLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDITT
                     YTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQF
                     PWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVIQS
                     KHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAAD
                     NNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEIT
                     TKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
BASE COUNT         4312 a         2769 c         2269 g         4506 t
ORIGIN      
        1 tgaaaaaggc gtttagtttc gagtatgaag aaaaattttg tgaaaatggt tcctcacgtt
       61 tttgcataaa tttgacttaa taccgagaaa ctgatccctt ctgtcataac ctctttttat
      121 ttatgtctgt ttctttttga aaacaactat tttttcaacg tttactctct tgccaatcca
      181 acatcatcta acggatacaa ctatttcaat gattaccatt acactaaaaa atcggaaaca
      241 cacctctccg aacacaaata cataagacta tagaatgttt catttaagaa aaaaagcgtt
      301 tcattatcaa aaaggtaaga tctcctttaa aatgaaatta tctgtagtac taataatgca
      361 gacaatttta tgaatctgaa aggagcatct ccaatgaaag cagtcacttg gcaaggaaaa
      421 cagaaaatgg aaatcagaaa cgtagatgat ccaaaaatat tagaaccaac agatgcaatc
      481 atccgtatca cagcaacagc catttgcggc tccgatctgc atctttacca tcatggtgaa
      541 gcagttttgg aaaaagggta tgttgtagga cacgaaccaa tgggaatcgt tgaagaagtg
      601 ggatctcaag ttcaaacatt gaaaaaaggg caacgtgtgg ttatcccttt taatattagt
      661 tgtggtcatt gtcatttctg cctgaatcac atggaaagcc aatgtgatga atcaaatcca
      721 gatcagttat atggcgggct tttcggattt ggcaagttga acggtaatca ttggggtggt
      781 caagcggaat atctaagagt tccttatgca gactctactt catttgttgt accagataat
      841 gatcttcctg atgaaaaagt tttatttcta tcagatattt tgcccacagc ttattggagc
      901 gttgaaaacg caggagtaaa aaaaggcgat acagttgtga ttctaggttc tggtccagtc
      961 ggtctattcg ctcaaaaatt cgctgttatg gctggagcag agcgcgtaat cgcagtagat
     1021 ccagtacagc accgtctaga taaagcggct aattacaatg gggttgaaac ttatttctta
     1081 gaagacacgg cacaagctgg aacagaattg tatgaactgg ctaaaggtgg cgcagatgtc
     1141 attatcgatt gtgtaggaat ggacggatta gagcctgtca aagaaaaagc gaaaaattta
     1201 gtaagcttac aaagcggcac aatctctcca ttacagatgg catcgcaagc tgtcaaaaaa
     1261 tttggaacag tccaagtaac tggtgtttat atgactccag cttcttctta cccgctgcaa
     1321 gaatttttta tgcgggatat cgctgtcaag catggacagg caccaattat ccatctaatg
     1381 ccaaaaattt acgcaatgat tgcagaagga ctattcgatc ctacacaaat cattactcat
     1441 tcgctgccac tatcagaagc agcacaagca tatgagatct ttgacaaaaa agaagataaa
     1501 aatataaaag ttgttttgaa accttgaatt cagtaaaaaa tacaggtgat tttctttatg
     1561 cccaaaatca aacgaaatac ccatgagatc gaaataggaa aagaagaaga tatcgaaata
     1621 cgaggacgtc gcttccgctt ctatttccaa aatcgttaca cattgatctc actggctgtc
     1681 gatttattaa ccgggatttt ctatattttt ggaagccttg cttccttaac taaaatcccc
     1741 gatcgatatg gcacctattt ttatttggct ggtgctattt tcttgacgat tcgtcctatt
     1801 ctcagaatcg taaggaacat ttttatttac gacgaaaaaa aagcaatgaa gagaacaagc
     1861 aaaaaaaaag aggcatgaga atttttcaaa tctcatgcct cttttttcac cctatcgtat
     1921 cactttgata cagacgagcg gtcgtcccac tttcttcctt gaccattgtc aaaaatgtcc
     1981 actcgtatcg ttcataaaac gtggtatgat ctgtaattaa gtaaagtttt tcgtacccaa
     2041 gttgatgcat ttcttttctg atttccgcta atatccgctt ggctatcccc tgcttacgct
     2101 tttccggttc aacaaacagg gcacaaagat ttggtgtcag atcagggcgg ttatggaagt
     2161 cgttttcaat gacgcccgct cctccgacga tggtttcttt ttcatctaag accacatacc
     2221 attgaggaat actttcctta ttagcgattc cagtacgaat actttcctca tacacaacag
     2281 caggaactcc ccattttgat gaaaaccaat tcgcgctttg ttttactaat tctgggtgtt
     2341 ctcttaattt gatccagtta tatgtaacca atgtttaaac ctccgactaa aataaaacgt
     2401 ttacaaaaat tatacaagtc tttatgaaaa ttagcaatga caacaatagt gatgtaaaaa
     2461 aaaaaacgga aaacaatcac ttgttctccg ttttttgatt gatcaagcat ctaaagcttc
     2521 ttttcttctt tcttggatcg tagctacctt gacgaacggt agatagatca aaatagaaag
     2581 aaccaaattg acagcggcta gtacaccacc tgcaatactt tttgttgcca atacaccgcc
     2641 aataattggt ggagttaccc atggaggcat aacggtagct gctggcacta aacctgtaga
     2701 agtcgcaaag taagcaacac taactaagac cattggtgtc aaaataaatg gaatgaacat
     2761 gatcgggttc aacacgatag gtaacccaaa catcgttggt tcattaatat tgaaggacac
     2821 ctggcgcaat cgacaagttt gttacaacca tatatggttt gtttttacgt cctactaaat
     2881 aaatagctaa cagtaaacct aaagttgcac ctgttcctcc taagttgaca aagctgtcaa
     2941 agaaaggttt gttcacgata aacggtgcgc tatgcccagc tgcgattgca ttaacgtttg
     3001 cttcaatggc tggcgcattg attgtttgca tcaaaggatc gaccatattc gctccgtgta
     3061 aaccaaagaa ccataagaat ggtgtgataa atgcaagcag taaggcagat ggataagagt
     3121 ttgcaagtcc cataaatggt tcttggacca ctgtatagaa agaacctacg atatcatcaa
     3181 caccgaatgc agcaaaaatt gcagcaacta aagcaaacgc agagatagtg atcattgctg
     3241 gtagtaatga agcaaatgct tttgcaactg ccggtggcac accatcaggc attttgatga
     3301 tcaatttttc atttccgctt aaacgtacaa agatttctgt tgaaataatc ccaacaataa
     3361 tagcaataaa caaaccgttt gagctcatac ctaatgctcc gcctaaagcg aagaaagagc
     3421 ctaaagaaat cacacctgcg gaaacaccgt cttttcggta gccgttagct aaatgataag
     3481 caagcaagaa agcaatcaag acagaaagaa tggcaaatgt accgttccaa gcagcagccc
     3541 cgaatccttt ccatgattca ccaccaaaaa ttgagttcat caattcttgg aacccgggaa
     3601 tcggtaagtt attgatcatt actgctaatg ctcctaagat cattaacggc atactcacca
     3661 taaatgagtc ccgaatcgca actaaatgcc gttgtgcacc aatttttgat gctacaggta
     3721 taaaatgttt ctccataaat gcaacaaatt tatccataaa tcttccctct tttctttact
     3781 gtagattacg cgttcaatcg acgatacaga tcaatgatct cttttgctaa atctgtaaaa
     3841 gctatagatg tcatcagatg atcttgactg tggaccgtca aaagcgtgac ttcaacgtga
     3901 tttccttgtg cttcttgtgt cagcatctct gtttgagagt gatgtgcttg gactaaagat
     3961 tcctctgcat ctttgatttt ttcatctgct aaagtgaaat cacctttttt cgcagcagca
     4021 atcgcttcca ttgcatcgct ttttgcattt ccgccaaaca tgatcagacc catgatggct
     4081 tctagatttt tttgatcttc catttattgt atcctccgat aatttttatt atttgtttat
     4141 tagtttttct gcttggtcga gtactttttc accattcatc atgccatagt cagccatatt
     4201 gattacatct aaaggaatgc ctttaggtgc tagcttttca gcaaattgat tttgcataaa
     4261 gcgtacttgc ggtcctaaaa gtaaaacgtc tacattttta gattctagtt gattatccgc
     4321 atctgaagca gatacagcaa agatgtctgc ttccattcct tttgcttctg ctgccttttg
     4381 catttttgtg actaggagac ttgtactcat tccagctgaa catacaagca tgattgtttt
     4441 cttttccatt ttaaacacgt tcctttctat acttacactt gtatataagc aagtagcgtg
     4501 ccaactttaa aagcgcttta aaaagttgat atcatcacat ttaaggtcta taccaagttg
     4561 catacacact aaaaaagaaa gcgcacacta aacacacaaa ttaattttta ttaccttttt
     4621 tcttttaacg tgcacaaaaa aagttgtgac acaaaacttg tcacaacttt tttcaaataa
     4681 acggtattca aaagcttgca tctgcggtaa taagtccaac caagttaaaa acataagatg
     4741 ttgtttttac tttgctattc ttattacttg atgcaggaca gctttttcac aacctctcaa
     4801 taaacggtgt tcaatcagct gaccctgggt attagctcaa aacgctggat tcacaacctc
     4861 ttttatttca aataaccagt aaatacaatg aacatctaca aaaaacttct atttatttat
     4921 agatttcgtc aggcaaatcc aattctctct tatcaatcaa agtctgatac cacgaagcag
     4981 attttttcaa tgttctgctt cgttcatcgt tcaattcgat tcgaactaat ccatatcgat
     5041 tcttaaatgc attcattggt gacacacagt cagtgaatgc ccataacata tagccttcgc
     5101 aatttgcgcc ttcttctgtt gctttgatca agtaatgcaa atgctgtccg ataaattcga
     5161 tacggtaatc atcttgcacg attcctttct catccatata ctgttcttca tattctcttc
     5221 ccataccgtt ttctgttatc agccaaggga tattatgata attttctttt agatacatgg
     5281 ctatatcata catgattttc ggatagattt cccatcccct ggaattattc attttcttcc
     5341 caggtaaatc aaagacttca taatatcgtt caggatggaa aggtgtctct tcattccatt
     5401 gataacgagg ggcgcgaacg cgtttaggat aatattgatt gattccaagg aaatctactg
     5461 tatgatgctg aatcgtttct aaatcctctg ttgcaggatc gaaataaatc gattgttttt
     5521 gacacaactc caggaactct tctgtgtagt atccttttac catcggatca aaaaatactc
     5581 gattataaaa caaatcatac atataagcag ctttttggtc ttctggagaa ttggatcgag
     5641 catagaccat ttcaggattt aaaatacagc caatccttcc accataattt ccgctgcggt
     5701 aaatctctac tgctttagcc gttgctaaaa ctttatgata attccacatc atccactttt
     5761 ttgtgttttg ttcatgcggc cagcgaacag catccaaata gcaacgcgtt tggggaacga
     5821 ttggttcgtt gaatgtaaac cagtttttta ccctatcacc gtaacgatca aaggcaattt
     5881 gagcatactt agcataaaaa tcaactactt ttcttgaaga ccagccatca tatttttcca
     5941 aaagaaaagc tgggacttca taatgttcca aacaaatcat cggttctacg tctgcttcga
     6001 tcaaagagtc gatcatttca cttatatgct gagcatattc ttcatctact atacagttct
     6061 cataatcagt aaaaaaacga gcccaattga tagaagtccg ataatgtgtc agatggatgg
     6121 atttcatcag atccacatcc tgctggtatt gttccataaa attagttgct acggctgggc
     6181 catacccatt atgccaaaca aaatgttcat ttttatacca gctatctata aacgaatcct
     6241 gtccttcttt ttttcctttc caaccttccg tttgccaagc agaagatgca gcaccaagaa
     6301 taaaattttt tggaatagta attttcatga tttcctcctg ttttttagat cccatcattt
     6361 tccacacgat ttgctacttt tacaaatggc agatagatca aaatagaaac aataatacaa
     6421 acaagttgcg taataactgc accgatattt cctgctgttg ccagataagc attgacgatc
     6481 ggcggcattg gccaagggac cattacaact gctttcgccg caaatcctaa agcggttgca
     6541 aaataaccaa tcgttccagt gataagaggc gttaagataa acggaatagc taaaattgga
     6601 ttcagcatga tcggcatacc aaaaataact ggttcattga tgttgaagat cccaggagca
     6661 agggataact tggtgatttg tttcatatct tcccgttttc caactaacaa tactgcaatc
     6721 agtaaaccga tcgtgactcc agacccgccc atactcatat acatatccca aaatggcata
     6781 gtaataatgt tcggtacttc ttttccagct tcaaaagctt ccgtatttac agcaattgcc
     6841 gctaaaagca acggttcccg tatcggcttc accatttgat ttccatggat accaatcacc
     6901 caaaagactt gcgcaataaa catcaatagc aaaatacccg gtaacccttg tacgacacct
     6961 tctaatgggc gttgtacgac attgtaaatg atatcataaa ggtacattcc tgtaagttct
     7021 ttgatgataa atcccgcagc cgcgataccc gatacagtca gaatcgtcgg gaataaagca
     7081 gaaaaactag cagaaacatt cgttggcacg gtatcaggca ttctcagctg tagtttcttc
     7141 tgtttcctca accagcaata aagttcaata gaaaggatgg agaccaacat tcccaaaaat
     7201 aaccctttcg tatctgtata ttgtttagcc aatacgtttt ctactataac agtctgattt
     7261 tcattcacta attcataaac agttggatta acagataaat aagacatcac tgcgatgata
     7321 ccagggaata caccatccac tttattcagc ttggctaatt cgatccctat cagaaaaaca
     7381 gcatagatgg tcaagaaact tagtgtgaca tagctgatgg cagatgcgat aggctttaat
     7441 tcttctaaaa aacgcaagaa acttatctgt gctaagccat tttccgagtc aaagaccatt
     7501 gctgaaaaca atgtgccaaa agcacccgta ataattaccg gaatcaatgc agcaaatgcg
     7561 ttttttatca ccatgatata ccttaaatta ttgattctcg ttgccacgtt ccctaaaaca
     7621 ttggctaatt tatccataaa actcattcca gatcccctca ttcctgcttc ttctccttga
     7681 cgtcatctct ttttgtctat tagtcagcgc ttacatttcg atgaacagaa actatttact
     7741 cctctttttt accaaatata aaacaaaaat tcatctgatg tatttatcat aaaatacatc
     7801 agatgaactg tcaattagtt tctttttctc ctattatttt ctgtaattct ctccgattta
     7861 ttgccatatg gacagtcatt gcatcaaacg cagcaagtgc attccgcctt tcgatggcct
     7921 gaacgatctc tgtatgaata tcgatcgtct cgattttcag atgctggata tcataatttt
     7981 tattaaacaa agcaattgat tcattaatga ttgggataat atgcagcaag gctacgtttc
     8041 cgctagcttc tgcaatcatc gtatgaaaat cgatgtctaa ttgaacatgt tcttgtgtgc
     8101 cttctcgaaa agaagtttca atcttttgcg ttaatttttt catttggacg atttgattct
     8161 tcgttgcata ttccgctgcc aaacctgcca tcttaggctc caataaatat ctcagttcaa
     8221 ataagtctcg tatcatccga tcctgatctt caatcaaaga aaaaccgagt gggtcattgg
     8281 caatccctcg cttatcactg acaaatgtcc ccgctccttg ccgaacttca aggatattcc
     8341 tggaagctag agcccgcaca gcttctcgca ccgtgcttcg ccccacctct aaataatcgg
     8401 acaattcata ttcattcggc agtttatctc ctacttgcaa ctgcatttcc tttaaatatc
     8461 taaggatctt gtcagtagtt acttctacta gggttttatt ttcttccaaa ccacatacct
     8521 ccttttcatc tgatgtattt tttcgtaatt attataacac gtttgaatca tctgatgatt
     8581 ttttgtatac aaaattgatt aatccgttca tagacataca aacgaagaag atatttacca
     8641 taaaaaagac taggataaaa ttcactccta gccttcgatc atttttattt tgaacgacaa
     8701 aaaatatgat gttcaataac agacgatctt cattcgattc ttgatgtcat cttttgtttt
     8761 ttttaatata tggataaaaa gtttgattac atcgtttcta ttctagaatt tggtcgattc
     8821 tcaattcttc ttctggtgag aaatctaaat tatccatcat tcgaacactt tcttgtaact
     8881 gacttaaccg acttgctccg accagtacac ttgtaacaga tttttgtcgc aaattccatg
     8941 caagggccat ttgcgctaat gattgtcctc gtgatacggc gattgtttgc agtgctttga
     9001 ttttttccag agttgatcca acttgttctt ctgaaaggaa tggtatttcc ttacgatgtg
     9061 ctctagaatc ttcaggaata ccatgtagat aacgatttgt cagcaaccct tgagcaagcg
     9121 gactgaacgt gattgcccct agcccttctt cttctaatac tggagataga tcgtcttcta
     9181 gtagtgcacg agaaaacata ttgtagcgca tctgatgaat aatgaacggt gcttcctttc
     9241 tttttaaaat ttcagtcatt ttttttgtat cttctccatt atagttggat ataccaatat
     9301 ataatgcttt tccttgtctt acaagttgca tcaaagcttc tgctgtttct tccaaaggtg
     9361 tatcagggtc tgggcgatga tgatagaaga tgtcaacata atctagcccc attctttgga
     9421 gactttggtc acaacttgaa atgatggatt tacgagagcc ccattcccca tatggccctt
     9481 cccacatatg ataacctgct ttgctagaaa taatcagttc atcacggtag gcttgaaaat
     9541 cttctctaaa aatacgccca aagtttttct ctgcagctcc agcagggcct ccataattat
     9601 tcgcaaggtc gaaatgggta attcccatgt cgaatgcgcc tcttaaaatc tctctttgat
     9661 tatggatagg atcataatca ccaaaatttt gccataatcc gagagataaa atcggtaatt
     9721 tcaaacctga atgaccggat ttacgatatt ccattttttc ataacgtgca ctatctgcaa
     9781 tatacaattt ttctcctcct catcaaatct ttttaaaacg ctttcttttt tctattttta
     9841 gtttactaca ttttaaagaa aaggagttaa tcaaaatgat tttttcgtat atttttttgc
     9901 catttgtttt ttactcgttg atagatcaga aattgattac gtgcttgctg gattttttta
     9961 taacgtttcg gttgtttttt gtaaaattgc tgatgatagt tttctgctgg ccaaaacgta
    10021 ccggctggtt cgatttttgt gacgattggt tggtggaaag ttcctgaact gtctagtttc
    10081 tgttttgatt gttccgctaa ttctttttgt cgttcgcctt gataaaaaat cactggacga
    10141 tattgcttcc ctctatcttg aaattgtcca aatgtatctg tgggatcagt aatttgccaa
    10201 tagattgtca gcaactcgct ataacttatt tctcttgtgt cataaatgat ctccacagct
    10261 tccacatgac ctgtgtaacc accacttact tgatcataat ttggtttttc aacatgtccg
    10321 cccgtgtatc ctgacaaaac agataggatc ccttttttcg attcaaacgg ctcgaccata
    10381 caccagaaac atccccctgc aaatactgca cgttcttgat agtcagcatc ttgcatggca
    10441 tgcttggaaa agtcatattt ttgctcctta tcaaatcctt ccgtaatcaa taaataaaag
    10501 tccattacat caggcgtcag attcattcgg atagctaatg gacgtagtgt tgcttctagt
    10561 tttgataact gttctttaac ggatatattt tctcttatgt cattctttgt ctgaatcaat
    10621 acttttcgtt cccaatctcg tgtattcgga ttcaaaatca gattataaag tgtttgaatg
    10681 aatatttgtt cctcatccat agattctcct cctttccgaa gaagacaagc tagtgacttt
    10741 agctgtaatt tatcataaag tgaggaaata agcgattact tcatccccct acagattttt
    10801 cgtataaaaa agagagaatc cttatcgaca gattctcctt tttaatcaat ttattttata
    10861 aatgaaaagt taatttacct tttatggaaa actattttaa aaaataaaca taaatatgca
    10921 gttaatgtaa caagataaga aataatagtc gttactgtat aacttgtgct tactttaata
    10981 tcagcaactc ctttgactcc gcttatttgt accaatccat tagcattcac ctgctccttt
    11041 acaggttgat gatttatttc tacattcgtt cctaaataag catatacagg aagtgtgatt
    11101 acttggctct tctcattagt tactctatat atgatagaac taccagttgt tttataagga
    11161 aggtttaccc attgactgcc aatctttgct tcgtgtttta ttatatgctc cttattctcc
    11221 aatgaagcga taggagaata atcatataaa aaataatcca ttcctttagt ggtatacgcc
    11281 tctactgttt ctttgtttac aacaatatgt cccggctgag aaattatttt ttgattgaaa
    11341 ttttttttac tagaaacagt taaagtgatt aataacaaaa cagtcataaa taaataaaat
    11401 agttctcttg tcttattgta tcttctattt ttgaaaaata tcatcgttaa tatcagagaa
    11461 gagaatatta tttgcaagct taagatccgc caaggaaatt gtaacaattt ggctggcgta
    11521 ttttgcagaa gataccatgg caccaaacta gttgtagcta gccaagtcaa acacgtacca
    11581 taataaatct ttttttctat gtttgttaat tttttaaata aaatcagggg aatacataaa
    11641 gataacagac caactagtcc cattgagtaa gtagttaagt cgttgttcat agcttcagtc
    11701 agactatcga acacattaga tgcatgagca tataaatttg tcacgctagg tttgttgatt
    11761 ttttggtaga gcatttgttc aaacatcgga taccaaaaag cactcgtcag aaccaatgtc
    11821 attcctgccg cactaaataa ttttttaaat atagcaataa aatctgcatt cttgaaacct
    11881 ttagaaacca aacgaataaa aatgataatt aatgctgtac tcattaatgt tgatagtaca
    11941 tggctgtaca ctagcaaact catactcaat gctagcttta cagacggata cttttcttct
    12001 tttccagaga tgatttgata agcataaaat aatacaggga taacaagtgt tattgcgata
    12061 gcttcggcaa ttgcggaacg atagtagatg tctactgtcc gataagcaga gaaaatatag
    12121 agacaactaa ataaaaatgc cgcttttttt tgttttaaaa accgctcgcc ataatgataa
    12181 gctacgagtg ttgtacacaa gttcaataac caaacgtaaa taatatagct tacaatcaaa
    12241 ttttttgtca tccaatataa cattacagct ggaaaaaaag tcagaaaggg ataaaaataa
    12301 tttacaccat atccagtata attgaatgtc tcataattaa tcggactggt aaaaatagtc
    12361 gataacccct tgattcgaga taagtgaaaa gaaagatctc cagtggtata aatactctgt
    12421 gtatttttga aaaagatgaa agaatatata ctactaacta taattaatcc actcaatatt
    12481 actacttttt tatttatttt cattcttctt gtttatctcc tttttagtca catatcgaga
    12541 atctttcaac ttattaggtg caaatcgttt aaaacttgaa tacaccacta aacaataagt
    12601 cagaatactg atccataaag ccatgagagc agttggagta tattttgttg taatttctat
    12661 cttattttct ccagcattta catccacatt cactaagcca tgttttttat aagagtcatt
    12721 tacgacttta ccgtttactt ttacctgtgt acctaaataa gcatatactg gtactgtcac
    12781 tttttgcttt ttgttgcttg ccactgtgta agtaatgtta ttatctgcag ctttatactt
    12841 ccctttttcc cacgattctc ctacttttac ttcatgtttt tctaagtgag gcctttcttt
    12901 tatcgcttct gttggggcgt aatcgtataa tcctcccata tctgatgttg tataacgtgg
    12961 gagtgtttct tcattgataa caatatgacc gtgttttgat tggataactt ttgcgtaatt
    13021 ttcttttgct gctatagacg tgacgagtag aaacaccaca gtagcgccaa tgattaacca
    13081 tgaatatttt ttattcatag tctttttcat aaaaacaagc gttatgatca ttgaagaaaa
    13141 aaagatttgg atacctaaga tacgccaagg aaactggagc aagcttatcg gtgttttttg
    13201 aaacaaaaac catggaaata aattagttac gcatacccat gtagaaacta cgccaacata
    13261 gatgattttt tcttttttct ccatttcttt cagtatgaat aaaggaaaaa tcaacgcaac
    13321 caatcctaat aaccccatag tgtatgttgt aatatcgtta tttaacgctt gaatgatact
    13381 atctgaaata gaaagtgctt ctagctgcaa atctgttttg aagggactgt gtatttcttg
    13441 ataattcatc tgctgcaaca taggatacca aaaatagcta gttaatgcac aagtcaaaaa
    13501 aacagccttt actaaattca cgaccacaaa ttttatatcg ttttttattt gcttgcttaa
    13561 aaacaaacga actataatca tacaagcaat caatgcacta cacaatagtg tagttaagac
    13621 atgagtatac acaagtagac ttatactgac agataaagcg atgacttttt tttctctatt
    13681 gaatatcaat ccataagcat aatataaaac agctgggata atcgtaagag cgattgcttc
    13741 tgcaattgcg gatcgataat agatatcaac tgttcgataa gttgcaaaag tatataaaca
    13801 actaaataaa aaagcagcat ctatcttttt aaaaaacttt tctccataat aaaaac
//
LOCUS       DAFBSV010000075        13487 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.076, whole genome shotgun sequence.
ACCESSION   DAFBSV010000075 DAFBSV010000000
VERSION     DAFBSV010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13487
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.076"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(164..388)
                     /locus_tag="LLB18_002138"
     CDS             complement(164..388)
                     /locus_tag="LLB18_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HBK5245125.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(586..2166)
                     /locus_tag="LLB18_002139"
     CDS             complement(586..2166)
                     /locus_tag="LLB18_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HBK5245126.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2567..3943)
                     /locus_tag="LLB18_002140"
     CDS             complement(2567..3943)
                     /locus_tag="LLB18_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBK5245127.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(4071..5189)
                     /locus_tag="LLB18_002141"
     CDS             complement(4071..5189)
                     /locus_tag="LLB18_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBK5245128.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            5331..5765
                     /locus_tag="LLB18_002142"
     CDS             5331..5765
                     /locus_tag="LLB18_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5245129.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(5843..6376)
                     /locus_tag="LLB18_002143"
     CDS             complement(5843..6376)
                     /locus_tag="LLB18_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HBK5245130.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(6470..7648)
                     /gene="mutY"
                     /locus_tag="LLB18_002144"
     CDS             complement(6470..7648)
                     /gene="mutY"
                     /locus_tag="LLB18_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HBK5245131.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7641..8438)
                     /gene="recX"
                     /locus_tag="LLB18_002145"
     CDS             complement(7641..8438)
                     /gene="recX"
                     /locus_tag="LLB18_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBK5245132.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            8545..9927
                     /gene="rlmD"
                     /locus_tag="LLB18_002146"
     CDS             8545..9927
                     /gene="rlmD"
                     /locus_tag="LLB18_002146"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBK5245133.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(10101..10679)
                     /locus_tag="LLB18_002147"
     CDS             complement(10101..10679)
                     /locus_tag="LLB18_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HBK5245134.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            11001..11471
                     /locus_tag="LLB18_002148"
     CDS             11001..11471
                     /locus_tag="LLB18_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBK5245135.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(11579..12805)
                     /locus_tag="LLB18_002149"
     CDS             complement(11579..12805)
                     /locus_tag="LLB18_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBK5245136.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
BASE COUNT         3958 a         2719 c         2248 g         4562 t
ORIGIN      
        1 taaagaacac ttttgtctca cgctctaaac acgtataaac ggcgaaagca gaagcaactc
       61 cttcggaaat aagctgaaat tcacgaaaat tgcttttcaa atttttgtga attccagctt
      121 atttcttgga gttaaacgct tctgtctcag cctctttttc tttctagctt tttgattttt
      181 ctcttttctt ttgtactttt ctcttttcat tttcagttct acgcgtgtct ttatttttaa
      241 ctttttcctc tttatggatg attgatcgta ctttttgtgc aatttgctcg tttttgtccc
      301 agtcttttac atctaataat cgacataatc gtaacatctc ttcttttttc tgtttttttc
      361 tttcacgtct ttgccattct gtttccatgt gtcacactct cctttcttta atcatatgta
      421 cgcaaaataa tttttatatt tttttgatta gacatttcta tgattttaat atagtaaaaa
      481 gagccgtcac ggaaaatccg tcacggctct aaacaaaata tgagaggctg tttttgtttg
      541 gctattctta ttacttgatg cagggcagct tgtgtcaaga cttctttaca tcaaactttt
      601 taattttaca ttgggatatt tatccgcaaa ccagcgttct gcaaattggt tctcgaataa
      661 gaacaacggt tggtcgaaac ggtcacgagc caagatattg cgacttgaac tcatcttctc
      721 atccaaatct tctggatcga tccagcgagc gattttgtgt cccattggag acatgattac
      781 ttcggcgtta tactcattta acatacgata ttggaatact tcgaattgta gctgaccaac
      841 agctccaatg atatattctt ccgttagata tgttttataa agctgaatcg ctccttcttg
      901 aactaattga tagattcctt tgtggaagga tttttgtttc atgacatttt ttgcagtcac
      961 tttcataaac agctctggag taaatgaagg gagttcttca taagcaactt ttagttttcc
     1021 ttcgaacaat gtatccccaa tctgataatt gcctgtatca tatacaccga tgatatcgcc
     1081 tgctactgct ttttcgacgt tttctctcga atctgccata aattgtgtga cattgcttaa
     1141 tttcagtttt ttatttgtac gttccaacca gacatccatt cctcgttcga atgttccaga
     1201 acagattcgg acaaaagcga ttcggtcacg atgggctgga ttcatatttg cttggatctt
     1261 gaatacgaaa cctgaaaatt cttcctcata aggacttacc atctgatcat cttgtgtttt
     1321 gtgtccataa ggagctggtg ccaattcaac gaaagtctct aaaaaagtct gtacaccgaa
     1381 gttagtcaat gcagaaccaa aaaatactgg tgtctgatcg ccacgagcaa ttttttcttg
     1441 attaaatgca tctccagcct ctttgattag ttctacttct tctaagactt gttcatataa
     1501 ggaattttca gttagaggat gattttcggg aagcagtcca tcttcatcca attctactaa
     1561 tcgttcatcc tgataatttt ccggacgata aaactctaca cgattatggt agatatcata
     1621 aagaccttct agccctttac ccataccgat tggccaattc atcggataag attcgatatc
     1681 taatagctct tctaattctt ctaacaattc caatggttca cgaccatcac gatctagttt
     1741 gttgataaaa gtaaatatcg ggatgccacg tttttttaca acttggaata atttctttgt
     1801 ctgtgcttcg atcccttttg cactatcgat taccatgacc gcactatcca cggccatcaa
     1861 agtacgataa gtatcttcag aaaaatcttc atgtcctggt gtatccaaga tatttactcg
     1921 tttcccttga taatcaaact gcataacaga actagtaaca gaaatcccac gttgtttctc
     1981 gatttccatc cagtctgatt tggcaaaatt acctgttttt ttgcctttta cggtcccggc
     2041 ttgacggata gccccaccaa acaatagtaa ttgttctgta atcgttgttt tcccagcatc
     2101 cggatgggaa atgatcgcaa aagttctgcg attgtccact tgttgcttta attttggatt
     2161 attcataacc taactccatt tcttccattc aattatttat attttctcta ggcacagatt
     2221 gtccgatctc ttaaagaaag acaatttcat atagggctgt gacaaaagcc gtgtagcagt
     2281 ctctttttcc gagtaaacgg cgttctagag acagcctatc agcaataagc ccacccaagc
     2341 caaaaatacg aaaagctgtt tttgcttggc tgctcttatt acttaatgca ggatagcttt
     2401 ttcacaacct ttgtcaacta ctacaactga atcagtatag catggattca gcgaatgaaa
     2461 aagccaccaa accataagag tcaaatattt ttttgtcagc tgactaaaag aaaagacgtg
     2521 ttgcttgttt attcaagcaa cacgtctttc ataaccaagt ttccaattat cttcttggct
     2581 cgtcatcttc gaattctttt ctgaagtatc ttcgttcttc ttcaggttcc gcttctgttt
     2641 cttccggatc atgaaaaatg acacggattt taaggattcg agaaccttcc atttcttcag
     2701 aaaccagcgt aatattatcg acatcaaacg ataacttttc gccttcatcc ggaatcatgc
     2761 ctaatgctgt aatcaaataa ccagccatcg tatctacatc actcatatgc agatcactgt
     2821 caaaagcttc attgaactca tcaatcagca tacgtccttg gatgatatat tcgtgttcat
     2881 cgattttttc ataaagattc tcaacttcat ctgattcatc atcgatttct ccgacgattt
     2941 cttctaaaag gtcttctagt gttgctaacc caacgacgcc gccatattca tctaataaaa
     3001 tagccatctg attctgcgtc tttttcattt catataacag atcatcaata aagaccgttt
     3061 caggaacgaa taaaggctcc tgcatgattt tcttgatatc taaattatca aagccgaatt
     3121 tatgggcagc ttttagtaaa ttctttgtat gaaggattcc gactacttta tctttgtctt
     3181 cgttataaac agggattctt gaatagtttt cggataaaac ttcattcaca ttttcttcca
     3241 cagtgtcgtt gatatcaatc ataaatgcat ccgttcgtgg gaccatgact tctcgggcaa
     3301 ctttcgtatc aagagaaaaa accccttgga gcatttctaa ttcttcatta ttcaatacgc
     3361 cttcgttttc aagcatataa cgcatttcat ctctggtcat ttttgaatct tcatcatcaa
     3421 aagtcatcgg cgtgatacgc gccaataaac ttgtggaagc agaaagcagc cagacgaagg
     3481 gcttagctac tacaccaatc aagcgtatca gccctgaagt gaactttgcg acttcttctg
     3541 atttatttaa agcaatacgt ttagggtaca attctccaaa aacaatcgat acataggtca
     3601 aaatagccag cacaatgata tttgcaatat tttttgccgc tgtgccgcca cctaataccg
     3661 gagctaaccg ttccgataaa gtattagcta gtgaagcacc agacaaaatg ttgaccaaag
     3721 tgattcctac ttggattgtc gataggaaat tatttggatt ctgcaatatt tttaaaagct
     3781 tttgagattt cacatctcct tcatcagctt tttgctcgat tcgattctta ttgatcgaaa
     3841 caacagcaat ttcggaagct gctaaaaaag cattgatcaa tgtcaaaacg atcaataata
     3901 aaatctgcgc taacagcgac tgactctcag ggtcagcatt cataatcgca ttctctcctt
     3961 ataaaattaa tttttagttt acgatagaaa aaaacgtggc actatagcca cgttaaaatg
     4021 gtatcacaaa gcaattttct ttgcaataaa aacaagtgta ctaaaactac ctacgaggtc
     4081 gtagcaattt tcttcttgtt ttcattttgc ttgtcttctt tgacgatttt gattatatag
     4141 gaaatgatcg tcttgcagat tgcgtaaaaa ggaacaccta agaagatacc aagcaatccg
     4201 gcaatatttc cagctactag aagaacgata atgatcgtta atggatggat tttcagtgat
     4261 ttcccaatta cattaggata aatgatattc ccatccaact gttggacgat tagcacaacc
     4321 acacaacaaa gtaatgcttt taccggatca ttgaagactg ttactagaaa tgcaggtgct
     4381 agtcctagat aaggtcctaa atatggaatt aggtttgtca atcccgcaat gaccccaaat
     4441 aagaaagcat aatccacacc aattaccata tatcctaaaa atgtgaaggt accaacgaat
     4501 aaacattcga ttgcttgtcc gctaatgtaa ttagccaatg ttttattcag ttgccccaat
     4561 aactccacaa tttggtttct tcttttttct gggaaaaact gttggatgtt tggcactagt
     4621 ttttctccgt ctttcaacat atagaacaag atgaatggtg ctgtaatgat tactacggtt
     4681 gccgaagcga tcgttccaac gatcgaacct aaactattgg atactccact aaggaattgc
     4741 tgaatgattg tcccgtaaga aatgtctaat tgctcaaaat atttattgat atctacttcc
     4801 ttgaacaaag gcaattcggc tacctctttt aaccagcttt ctacctgttt gatgaaatca
     4861 ggcatattag atgccaatga ggaaatttgc tgtactagac ttgggatgac actaagtaaa
     4921 atccaaataa ttgctgcaac taaaaggagc agcacaattg cgacagccca tattcttttg
     4981 atttttgctt tcatcaacag cttgacaata ggattcaata aatagtaaag aaagcctgca
     5041 atcagtacag gtgcaaataa cgtggaaaaa aatgtcccga tcggttcgaa aataaagttt
     5101 atttctgatg aaatcatgat caatgcagct atgatcaata attcaagcga ccaaaacatt
     5161 agtttagact gtctaagttt ttcaaacaat agatttcctc ctttctttct tactagtata
     5221 tattatattc gttaaaaatt cttttattct ttttttattt ttgaaaactt gccatacttt
     5281 ttatttgttt tattttccag tatactatac gaaaggaagg tggctagacc atgaaagttg
     5341 tacaaacaaa agatacaatg agcaatattt acttagatgc tgtacggatc aggcatcaag
     5401 tttttgtagt cgaacagggt gtgcctttgt ctcgagaaat agacaaagat gaagcccatt
     5461 gtatccactt cgtcctgtac tcagataaaa aagaaccgca aggaactgta cgtcttttgc
     5521 ctttagaaaa cggaaaaatg aaattacagc ggatggcgat tctttctgaa tacagacacc
     5581 aagggttagg aaaaatattg attgaagaag cagaaaactt tgctaagaat caaggctata
     5641 atacgatttt attaggggca cagtccacag ctgaaacttt ttacgaaaaa ctaggatata
     5701 cagcttacgg cgatcctttt gaagatgctg gcatgcctca tatttatatg aaaaagactt
     5761 tataaaaatt tatttcgaaa aaagcaaaaa acagcaagct tttgagaaaa atctctcact
     5821 ggcttactgt tcttttttgt gtttacttac gcgacaattg cttgtaacgg ttataccaaa
     5881 tatcaatata gccttccgag aacgggccat ctccattatt gatccagtca accagaatct
     5941 tcacattttc ttttaggatg aagtcaatat cgttcgggta attcatcatt ttgctgtgca
     6001 tctcatattc atcgacatcc aatagtcgtt tctcgccgtc aggaaatacc ttgatatcca
     6061 agtcatagtc gatatatttc aaggcctcat cgtccagcaa aaaaggtgaa gctagattac
     6121 aataatagga aacccccttt tctctgatca ttgctattac attgaaccag tattttttat
     6181 gaaaataaac aatcgctggt tcgcgcgtta cccatcggcg tccatcagat tcagtgacta
     6241 atgtgtgatc attcacgccg atcatagagt gttcgcttgt ttttaatacc atggtatctc
     6301 gccacgttcg atgcaatttg ccgtcgtgct tgtaactttg gatcgtcaca aactctcctt
     6361 cttttggaac tcccatagca acccttcctt aagcagcatt ttgtgctttg tgtttgggtg
     6421 ttcattacac cgacatcata attattatat caataaaaat gagctttgcc tagaaaggat
     6481 tcctattgtt tcgatttttc tctaactgat ctaccagttt catttggacc ttaggaaaaa
     6541 cgaccgaatc aaatgcatca ggcttcaacc acttcgaagt tttgttctcg gtaaattctt
     6601 gttctgctcc ctcggttgcc cgtccgtaaa aaaggagaac atgccatttc agatgactaa
     6661 aaatatgagt aacttctcct aaatgtcgtg tctgccaaac aaagagttcc tgcttttcaa
     6721 atgggagatt ttgctcttct tctgctacta ggtcatcaaa cagatcgatt tctggctttg
     6781 tttcccattc ttttttcaat cgctcatact cctcttgtgt cacttccatc attggaaatg
     6841 tccacatatt cgccagcaat ttttggctat ctctttcttc aaaataatac gctccagaat
     6901 gattttgaag agctgcactg atataataaa cgtcttttgg ctttgctttt tttgttttta
     6961 caggaaaact cgtttggatt cctcgtttgt tagctaaaca aaaggcttgg atcggacaag
     7021 tctcacactt tggagaagtt ggtgtacaga tagctgaacc tagatccatc attgcttggt
     7081 tgaattcacc tggatgcttt tcatcaatga ttttccgcat cgcttcatca aagattttcc
     7141 tgctagaagc ttttgcgatg tctgcttcaa tgcaaaacaa tctgctgact actcgcatca
     7201 cgttgccgtc aactgcaggt tctggaagtc caaatgcgat acttgcaatc gcgcctgtcg
     7261 tatatggtcc tattcccttc aatgagctaa tttcttcagg cgtttgcggc atttccccat
     7321 caaattctga catgatctgt ttagcagcag cttggatgtt ccgggctctt gagtaataac
     7381 caaggccctc ccatgctttt aaaagctttt cttctggagc atttgctagc tcttcaattg
     7441 taggaaacca ttccatgaaa cgataaaaat aatcgatcac tgtgtctact ctggtttgct
     7501 gaagcatgat ctcagagatc cagatacgat aaggatcacg attatagcgc caaggcaggt
     7561 ttcttttttc ttgttcatac cattgaatga actgatcttg aaattctttt gtttctttat
     7621 ctgtccattt ttcccattct ttattcactt tcctcttcct tttccgtaat gaatcgctgg
     7681 atcatatcca aatcaaatcc tttttgatat aagctttgct ttacttttag atttcttttt
     7741 ttaggttcaa accttaaatt tcttcgccat agtttatctc cttgtttgac taaataatca
     7801 tattctattt cttgatctgc ttcttgcgga agatcagcta tcgcttgttg gatcacttct
     7861 tgagaaaagc ctttcgtcat caatgtttgt tggatttttc tcaataattc tttttggctt
     7921 tttccgtgat tttttccaaa cgctttttcg gctgtctgat gtgcattttg aacttggtct
     7981 tcaaatgtat attggctgag cgcttgttca atgatttcag gtttcaaacc tttttgctgc
     8041 atctgctgcg ctaatttctt tggtcctttg tcacttaagc gcatattcgt gcgcacataa
     8101 ctttccccat agaccaaatc atcgacaagg tccaattctt ttaagcgggc tacgatttta
     8161 tttcgatctt cttgaaggat ttccttttct tttaagtatg ttcggatttc tttttccgat
     8221 cgcaactgat aacttaagta attcattgct aggtgaaaac cgaaatcagc tccgctactc
     8281 ttcttgatct cttggatagt ttcttcgtct aattcccgtc cttttaataa tcgatagcgt
     8341 actaatacat cttcagatac ttgtaaagct tctccttcag ataaatctac gcgatagaaa
     8401 gggcctttgc ctttactgat tctcgtaacg gttaacataa acatcctcct cgaacatata
     8461 ttctctatca taccacagaa aatccccgta atcaggtatt atatgttaga ataaaccaca
     8521 gaaaaaagaa aaagggagat acttatggca gaaacaattg tcaaaactgg acaaacggtt
     8581 cctttgaaaa tcaagcgttt aggcataaat ggtgaaggaa tcggttattt caaacggttg
     8641 atcatatttg ttccatatgc actaccaaaa gaagaagtac tagtgaaaat cacgaaagca
     8701 actcctcgct atgcagaagg agaattaata aaagtcaaaa aaacaagcaa agatcgcgta
     8761 gtggcaccat gtcctgttta ctatgaatgc ggtggctgtc aattacaaca cttagcttat
     8821 caagctcaat tggattttaa aaaggatctg cttttgcaag cattggaaaa attcaaacca
     8881 gcaggctttc gatcttatca acttttgccg acgatcggga tggatgagcc ttggcattat
     8941 agaaacaaag cacaatttca gttacgaaaa aataagcaga ctcaaaaaat tgaagctggt
     9001 ttatacgaag caaactctca tcagttagtc cctataacag actgcttggt tcaagaacct
     9061 cgaacacaaa aagtaatgaa tactgttgtt caactattga ataaatttga tgcacccatc
     9121 tatgatgaac ggacaaacag tggaatcttc cgcacaatca tggttagaat cggtgttaaa
     9181 actggggagt tacaagttgt ttttattact cgcagtaaaa aattcccgca aaaaaacgca
     9241 atgatccgtg agatcaatga acgactgccc gaagttgttt caatcatgca aaatgtccag
     9301 gcacaaaaaa cgtctctcgt gatgggggat gaaacgatcc acttatgggg aaaagaagcc
     9361 attgaagaac aaatcaatga agtgactttc gatctttctc ctcgtgcctt ctttcaactc
     9421 aatcctcagc agaccgaatt gctttatggc gaaggaatca aagcattaga tgtccagcct
     9481 aatgaaacga tcgtggatgc ttattgcgga gttgggacga tcggcttaag tgtagcaaaa
     9541 caagccaaag aagtacgggg aatggatacc gttcctcaag caatcgctga tgcaaaaaaa
     9601 aatgcggaaa gattaggata tcacaacact cgatatgaag tcgggacagc agagcaagtt
     9661 ctgcctaaat ggttgaatga aggttttcag cctgatggta tcatcgtaga tccaccacgt
     9721 acgggtttgg ataacgcatt gatccaatca ttattgaaat accctccaaa aaaacttgtt
     9781 tatatctcct gtaatgtttc tacacttgcc agagatctgg ttaatttaag taaaaagttc
     9841 aagattgaat atttacagtc cgtcgacatg tttcctcaga ctgcacgttg tgaagttgtc
     9901 gtgaagatga cgagactcgc tgactaaatg aaagaggttg tgaaaaagtc tgccctgtat
     9961 caagtaataa gaacagccaa acaaaaatag ctcttcatgt tttatgaata ctgtacttgt
    10021 gaccgaagag ttaacaggag gacactattt atttaaaaaa agggttgtga catagttttt
    10081 gtcacagccc tttttgatta ttattggata ttcacgtcta tcacttgata aaatgcattt
    10141 gtcgtatcgc tgatattcca tactgctaaa atcacattat atccttttcg atcctgcgga
    10201 agtgtgatcg tttggttgac tgtttttggt ggaacagttg ctttgtcgtc tatttttgtg
    10261 atcaattcaa aatcactaaa tttcaaaggt tgattaggat tccaagttgg tttggtaatg
    10321 tagtaatccc aagtacttgt ccgatgttgt gctgttaaat tccaagtaat atttaatgtt
    10381 cctggattaa ccatgttttt atgccatctg ttagatgtct gttcatctaa aggctcaaag
    10441 ccgctgactc ctgcactagc aatttttcca tcaatgaatg tatttttggt agcttcgata
    10501 ctttgcggtt cccattgtgc tcttccgaca ttttgattta agtttcctgc tgctgatgtt
    10561 cctaggtatg cacggcttcc tggagaagta atataaccat gcgcaaaacc tggaatgcta
    10621 aaaccgaaca accctaaact aactaaccca ataaacaata acgtactaat ctttttcatg
    10681 tagaaacctc cttcatttga taaccacatt gtaaacgctt tattgtatta acacaaacat
    10741 tatgctttta taattttatg ttgaagtaaa aaaggtgaaa aaagtaagat gcagattata
    10801 acagaagtag acgagaaaag tacaaataga aaacatgaga atcaaatcat atgatctttt
    10861 tcaaaaacat cattcatata aacaaatgtt caacttttta ataacaacaa ttatcaattt
    10921 ttttcttact tcacaaacta aatacaggtc ttgctgtgag ccttcatggt aaactaatat
    10981 tatagaaagg agttagtaaa atgaagatga taaaagatat tcgtttttgg gtttgtgtta
    11041 taggaattgt catattaggc tttttatcag ggttgcttag cggaaatccc ggaaaatatt
    11101 actattcttt gcaacttcca ccatttgcac cacctagctg gatatttggg ccgatgtgga
    11161 ccttactgta tatattgatg ggtatttctc tttatttgtt acttaatcac aacaacaaaa
    11221 aacagcgaaa caatcttgtc ggtctttttg tgattcagtt catttttaat tttatatggt
    11281 ctgctctatt ttttaattta agaaatattt tcattgcagc aatcgatatt acacttttag
    11341 ttattttctt gtcagtgctt atgtatcagt tgtggctgca tcatcgcctg gcaatgtggc
    11401 tcatgattcc ttattattta tgggtactat tcgcaactct attgaattat tcaatttatt
    11461 ttttaaacta agcgctaaaa agagacgtcc tgtaatttaa cacatagaaa aagtgccacc
    11521 taagttagat tttttgtcta atttaggtgg cactctttat taaccaaact atttttttct
    11581 agtacccact tgttgttcca tactcattat tctggtcata accataacca ttttgttcct
    11641 gtccagcgta aggatcataa ctttgagtat cttgacttgg tgtatagtac tgacttgtat
    11701 cttctgtttg ctgataatag gtattcggat cttggtactg atcatatgtg ttttctgaat
    11761 aggaagaata atcggtgtac ccttcactat tcgatccatc accgtttgtc gaatcgccat
    11821 cttccgaatc atcaaagaac atcattgaag cattctcatt tttcaaatta ggtaatgtat
    11881 cgcttgtttt tatatttaat tgtttcttca gttcattttg gatcgaaaga agatcatttt
    11941 ttcctaaaat ttgatagtag atatcattga tcatttgtcc ttcgccttgc aactggtctt
    12001 gtttgattgt ttcaaacgcc ggggtgtagt tcgtcgctac atcaagcatg tcatcccaat
    12061 ctaagtccgt cgtcacattg ttctcaactg cttttaaaat ttttctataa ttgcttacgc
    12121 catctaaact taaaacttta ttgacgattt tcgtcactac ttcccgctga cgacgttgtc
    12181 gaccgatatc gccttctgga tcttcgtgtc gcattcgaga ataggctaaa cctttttctc
    12241 cattcaatgt ttgttcacct actggtacat ggacaccatc caaagtaaag tcaattttat
    12301 tattcacttt gatgccaccg accgcattga tcaaatcttc catgccatcc aaattgatcg
    12361 ttacataatg atcaatagga atatcgagca gttgctcaat tgaatccatg gccatttcga
    12421 caccaccaaa tgcgtaggca tgatttaatt tatctaccgt tccataacct acgatattcg
    12481 tataaatatc tcggtccaaa ctgatgatcg ttgatttttt ttgtttcgga ttaactgtta
    12541 ctaccatcat cgtatcagaa cgtccttgtt ccgttcttcc taatccaccg gtatctaaac
    12601 ctaatagcaa aaccgaaaaa ggttctttgt catcaatgct tactctctca gaacgtttgg
    12661 aggatattcg attagagttt ttagaaattt tgtttactgt ttggctcgct tctcccataa
    12721 atctgattcc gtatgctgat aatccggcaa tcagcaaaac gaatacccct aacaaggtta
    12781 atagaacttt ttgccatcgc ttcataatac acctctgttt cacattttct aaaatattgt
    12841 ctcatataac tgttcaatca gcaaattcac tttttaatca taagaaaact ttaaaaaaca
    12901 tttttgtgta acgattatta ttttttaaaa tttctcaaaa ttcttaacta tcataccata
    12961 ccgtgaaaaa gatcgaaaga ccgaatacac gcagttcgca atcgttttat ctttttttat
    13021 gtattttttc cagaaaaagc gaacaacaag gtattttcca aataatcgtg cagtaaaatg
    13081 atcgcacata cctttcccat ctttttaaca gtctttgcct accgttcaga ttatcattcg
    13141 atttcacgac aatttcttcc tatgactggt ccttttgtta aacccatctt ctattcgttt
    13201 tatttccagc tcactgcatg gctcttaaaa tgactcgaac tagtgattgc attaccatca
    13261 tcttttaatg gatagatatg ctcctcttca aagtaaaacg attttctttt aaagtaatag
    13321 aattgacatg gtaatgagta tgtatactag tggtttcaca aatggtcttt tattcaacat
    13381 ccaaaaactg aaatttcttt aaaatccatt actaacgaag aaaatgttcc ttgcttgata
    13441 attagttagg acatgtcaag tgaacaaatg catttactta gccaaaa
//
LOCUS       DAFBSV010000076        13429 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.077, whole genome shotgun sequence.
ACCESSION   DAFBSV010000076 DAFBSV010000000
VERSION     DAFBSV010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13429
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.077"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(<1..914)
                     /locus_tag="LLB18_002150"
     CDS             complement(<1..914)
                     /locus_tag="LLB18_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBK5245137.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIY"
     gene            1342..1905
                     /gene="efp"
                     /locus_tag="LLB18_002151"
     CDS             1342..1905
                     /gene="efp"
                     /locus_tag="LLB18_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBK5245138.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            2006..2176
                     /locus_tag="LLB18_002152"
     CDS             2006..2176
                     /locus_tag="LLB18_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245139.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            2391..3650
                     /gene="lysA"
                     /locus_tag="LLB18_002153"
     CDS             2391..3650
                     /gene="lysA"
                     /locus_tag="LLB18_002153"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBK5245140.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            3637..4437
                     /gene="dapF"
                     /locus_tag="LLB18_002154"
     CDS             3637..4437
                     /gene="dapF"
                     /locus_tag="LLB18_002154"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBK5245141.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            4440..5321
                     /locus_tag="LLB18_002155"
     CDS             4440..5321
                     /locus_tag="LLB18_002155"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBK5245142.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            5318..6034
                     /locus_tag="LLB18_002156"
     CDS             5318..6034
                     /locus_tag="LLB18_002156"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBK5245143.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            6040..6735
                     /gene="dapD"
                     /locus_tag="LLB18_002157"
     CDS             6040..6735
                     /gene="dapD"
                     /locus_tag="LLB18_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBK5245144.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            6751..7752
                     /locus_tag="LLB18_002158"
     CDS             6751..7752
                     /locus_tag="LLB18_002158"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBK5245145.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEKPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            7749..9110
                     /locus_tag="LLB18_002159"
     CDS             7749..9110
                     /locus_tag="LLB18_002159"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBK5245146.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            9070..10221
                     /locus_tag="LLB18_002160"
     CDS             9070..10221
                     /locus_tag="LLB18_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBK5245147.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            10196..11365
                     /locus_tag="LLB18_002161"
     CDS             10196..11365
                     /locus_tag="LLB18_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBK5245148.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            11540..12919
                     /locus_tag="LLB18_002162"
     CDS             11540..12919
                     /locus_tag="LLB18_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBK5245149.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            13200..13429
                     /locus_tag="LLB18_002163"
                     /pseudo
     CDS             13200..13429
                     /locus_tag="LLB18_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4485 a         2339 c         2923 g         3682 t
ORIGIN      
        1 aagtaaatgt tttttgataa atagcggtct gctgcgtctg gaaaaatcgt aacgacacga
       61 tgaccaggtg gtaaacgacg aatttctctt aatgctgctg caaaagccgc accactcgaa
      121 cttccaacta atagtccttg ttctcgtgct aactgcctag tatagttaaa cccttctaca
      181 tcagagattg tctcgatctg attgattgaa aggggagaaa gaaacggcgg aatgaattct
      241 acaccgatac cctcaatttc gtgaggggct ggatcaccac catttaacac agagccctct
      301 ggttctacac cgattattcg aatgtcggga tatttttctt tcaaaaaggt agaagttcca
      361 gcaaaggttc caccactccc aattcctgct acaaaactat ggatattttc tttgatttca
      421 tgaaagattt ctggccctaa cgtatgatag taagcagcag gattatcttt attttcaaat
      481 tgaagaggca gatagctgtt tgatatctcc tctgcaagtt ttttactttt gctgatggca
      541 ccgatgattc cttgctcact aggagaatgg atgatctttg ctcccaatgc tttcatcaat
      601 tgttgttttt ctaagctaaa cttctctgga acaacaaaaa ccgttcttaa tttgtatgtg
      661 agtgcggcca gagcgatccc aattcctgta tttccggcag ttggttcgat gatcgtcgtt
      721 ttttcattga tttttccttg ggcaaatcct tctttgatca aataactgcc caatctatct
      781 ttgatacttc ctccaggatt taaatattct agttttgcat aaatagcaga acctttaggc
      841 atagaatagt gctgattgtc aaagcgataa agcggtgtgg aaccaatagc ttctgtaatt
      901 gtcgagataa tcatgtgggc ctcctaaaaa aagataataa aaaaaggagc tgactattaa
      961 atcagctcct tgaaagacat agagaaaaat tgagtagata aaaagataag ttacctggta
     1021 ctcattctat gaagggcaat taatagacat gacaaatagt atgctgcttt tatgcaccat
     1081 acaacagcaa cgattcaatt gtttttggtt gctgactgtc atgtgtatcc ctccaagtaa
     1141 aatttttatt aacgatagca tgaaaaaaaa taaaagtcaa aggcttgaaa gaaaaaaata
     1201 tttcgatagc atcgtttacc cgtgtttatt tttctgacaa ataggcatga gaccttaaaa
     1261 gatagagaat actctagttt tctggccggt tgtctgatac aataaagttg attatgataa
     1321 agaaaagaag gagcaaaaat aatgatctca gcaagtgatt taagagccgg tatgactttc
     1381 gtacaagacg gcaaactgat taaagttctg gatgcaagcc accataaacc tggtaaagga
     1441 aatacagtta tgcgtatgaa actgaaagat gtccgttcag gtgcaacata cgacacaacg
     1501 ttcagaccag aagaaaaatt tgaaaaagca catatcgaca caaaacctgt acaatatttg
     1561 tacacgatgg atgatacagc tttcttcatg gatttggaaa catatgagca atatgaaatt
     1621 cctgtagaaa cagtagaaga agaaatgaaa tatatcctag aaaacatgga agtaaaaatc
     1681 caatttttcg gtagcgaagt catcggcgtt caattaccaa caactgtcgt attacgtgtt
     1741 gtggaaacac aaccttccat caaaggtgca acagtcactg gttcaggtaa gccagcgaca
     1801 atggaaactg gcttagtagt caatgttcct gacttcatcg aaacagatga attgttggaa
     1861 atcaatacag cagaaggttc ttatgtaaaa cgtgcgtcaa aataattcgc taacggattg
     1921 ataagaattt gaaaacagag cttgacctct tgaaaggcag atcatcggat ctgcctttca
     1981 agaggttttt tgtggaatca gcaaattgaa aaataaaaaa gtatttgatt ttatttatat
     2041 tttgaaagat gaatggcaaa agctagagaa agaaaaaact gcacttattt atgaagaaat
     2101 tgaaatgatt cataaaattg aaaatatccg aactattccg aactatattg aagcgaaaat
     2161 attttttcat cactaaatag tgttgaattt atgtttttat gtataaatag cttctaatag
     2221 ttcgggtatt ttgtttttat aaccattttt attcttattt ttaaaaaaat atttcgaaat
     2281 atactagaca attcagaaaa ttttgtttaa tattattcca ataaaattca aatctttatc
     2341 aaatgaaatt ccaataaaaa cggaaaaaaa gtgaaaagag gaatgaaaaa atgacagaat
     2401 tgataattgg cggagtcaca gcaagcacat tggcagaaaa gtataagaca cctctgtatg
     2461 tgtatgatga agaaaagatg agacaaacga tgctgtcatt caagcgaggc tttgtatcga
     2521 aacgttttga tacaaaagtg ctttacgcct ctaaagcatt ccaaacgatt gagatgctgc
     2581 atttagttcg tgaatatgga ttcgggctag atgttgtcag tggtggggaa atctataccg
     2641 ctttgcaagc tgattttcct agagatacta tctacttcca tggtaacaac aagacgccag
     2701 aggaactgat ctatgcactt gaaaatgatt tgttgcatat tgttgccgat aatttgatgg
     2761 aagttgaatt attagcagaa ttaagccaac gctatttaaa aaaaatctgt atcatgcttc
     2821 ggttgaatgt cggagtagaa gcacatactc atgaatatat cgtcactgcg catattgatt
     2881 caaaattcgg catgagctat gaaagtaaag agtgccaaca agcccttcag ttgataaaag
     2941 aaagcagcta tctagagtta gaaggatttc atgctcatat cgggtcacaa atttttgatg
     3001 ttactgcttg gttagctgaa atcgacaaat tgacgaatta cttaaccgat tttgaccaac
     3061 ctctttcctt gaatcttggc ggagggtttg ggattcgtta tacacaaaat gatcagccga
     3121 tcccagtcga agaggcacta aaaaaactga ttgaatatac ggaagaagct ttggaaaaac
     3181 gaaaactgac cattcgtcaa ttactgatcg aaccgggtag aagtattgtt ggagaagctg
     3241 gtacaacact atacacgatt ggtttcatca aaaagacacc acataaaaaa tattactttg
     3301 tagatggcgg gatgacagat aatatccgtc cagctctgta tcaggcagaa tacgattgtg
     3361 atttagcagc aaaactgtcg gaagaaaaaa cagagaaagt gacgattgca ggaaaaatgt
     3421 gtgaatcagg cgatgtggta attaaagaag cttatttgcc gaaagcagaa tcgggtgatc
     3481 ttttagctgt ttattccacg ggagcttatg gatactcgat gagcagcaac tacaatcgag
     3541 cgacacgacc agcagttgtt tttgtcaata atggccaatc aagactgatt gttcgcagac
     3601 aagcattttc tgatctacta aggggggaag tttcctatga tccttcataa atataatggc
     3661 tgcggaaatg attttatctt attagattac gcagaagaca cagattatag tcaattagcc
     3721 gcttctttat gcacaaaaga aaaatatgat atagacggat tgatcgccgt aaaaatcgat
     3781 ccgttggaaa tgatctatta caacaaagat ggcagccgcg cgccgatgtg cggaaatggc
     3841 attcgctgtt ttgctcgata cgtaaatgat cagaacatga tgaatgaaca ggaattcaac
     3901 gtagagacat tagcaggcac aagaaaaatt acggtgttgg atccctcacc tttttattgc
     3961 agcgtagata tgggagtgcc agatgattct ccggaaaaaa tcaaagctaa tcaaacttat
     4021 ccaataaaaa accaggaaat agagatcaat ggtgaaaaag taacgatcac tagtttattt
     4081 ttaggaacga ttcataccgt tgtttttgtt gaaaatgcgc gtgaggaagt ctggagaaaa
     4141 agaggtgaac tgatctgtca tcatcctttg ttcaaagaaa aaaccaatgt caactttgta
     4201 gaagtagtca atgaacaaga attgatcgtc cgtacctatg aaagaggagt aggttggaca
     4261 cttgcttgcg gtacaggttg ctgtgcctct tatgtggttg ctaaggaaac tgggaaaatt
     4321 tcagcagatc aggtagttgt tcacttggaa caaggagact tgatgatctc tggtgaggat
     4381 gcgatacaaa tggctggccc agcagttcat gaatggacaa gaatattgga ggaatgaaga
     4441 tgataaaagg ttcgatcgtg gcgctgatca cgccgatgaa tgaagaggga tcagtagatt
     4501 atgctggttt ggaaaaattg atccaattcc atttagatga acaaacagat ggattattag
     4561 ttttaggtac aacaggagaa tcttctacgc tcacacaatc tgaggaggag cagatccttc
     4621 aactgacagt aaagaaagtg gctggccgtg tgccggtgat tgcaggagct ggaacgaata
     4681 atacgaaaga aacgattgaa aaagcgaagc attttgcttc tttgggggca gacgcacttt
     4741 tggtcatcac cccttactac aacaaaacaa gtgatgcagg actagctgct cattttacag
     4801 caattgcaga agcctcaccg attccgctta ttttgtataa tgttccttct agaacaggca
     4861 tgtcgattcc aatccatgta ttagtaaatt tagcagaaca tcctaatatc attggtttga
     4921 aagaagcctc aggagatatg gcttatgtga tggatgccgc tcggttgatt ggagaagaat
     4981 tcttccttta cagtggaaat gatgatttga tcctaccagt aatgagtgta ggaggaagcg
     5041 gtgtaataag tgtatgggcg aatatccaac ctaaaatagt ccatgaatta gtaaaagata
     5101 cgcaggacgg aagatggcag caagcaaaag aaaagcaatt aaatgcactt gaactgatcc
     5161 atgccttgtt cagtgagacc aatcctattc ctgtcaaagc agccatgtca ttattagact
     5221 taccttccgg acctctacgc ctgcctttag tttctctttc aaaagagaaa aagaaacaat
     5281 tagctcagct tttgttaaaa gaaaggacgg ttgaaaaatg aaaatcggac tgattggcag
     5341 tggacagatg ggaaatagag tcgaagaagt tgcacaagaa agaggagata cggtccttct
     5401 tttacggacg gcacctaaag aagcaactac gcttgctttt acggaactgc cagaactgct
     5461 tattgatttt tctcatccag ataatttaga gaaaatcctt tcgtatagct tatcatatca
     5521 acttccgtta gtcattggca cgacaggtta tacacaatca cagttccaag aaataaaaga
     5581 acatgccaaa catgtacctg tgatgtatag tgctaatttt tcgttcggca tcatggtgat
     5641 gaatcaacta atcaagcaag cagctgcaat gttgcaaggc tggcagatcg aactgattga
     5701 aaaacatcat agtcgtaaaa aagatgcacc atctggtact gcaaatatgc tgcttcaaac
     5761 aatccaagaa gtgcaaaagc tgcagcccgt atacaactgg caagggaaaa aaagagaaga
     5821 aaaccaaatt ggtgtacaca gtattcgtgc aggttcttta cctggtgaac atgatgtatt
     5881 gtttgctgct actgatgaaa tatttacgat caaacatgaa tctttttcta atcgaatctt
     5941 tgctgcaggc gcagtagaag cagcggactg gttgaaagat cagtcaccag gttattacaa
     6001 attagaagat ttattaatgg acaaaggggt gtaaaaaacg tggaagctca agaaatcatc
     6061 cgctacattc aaacggcatc taaaaagacg cctgtgaaag tctatctgaa tgtaaccgag
     6121 ccaatcgaat ttaaagaaag taaagttttt ggtgaaggaa gcagcttcgt tgtttttggt
     6181 gactatgaga cgattgctcc ggttttagaa gctgaatcag aaaaaatcat tgaaatcgaa
     6241 atcgaaactg ctgcaagata cagcgcagtt cctttgctag atattaaaaa aattaatgct
     6301 cgtatcgaac caggtgctat tatcagagat caagtgtcaa tcggcaacaa tgccgtgatc
     6361 atgatgggag cgattatcaa tattggtgca gtaatcggtg aaaacacgat gattgatatg
     6421 ggtgctgtct taggtggacg agcgacagtg ggcaaaaact gccatattgg tgcaggagct
     6481 gtcttagcag gtgtgatcga accagcatcg gccaaaccgg ttatcgtaga agacggcgta
     6541 ctggtaggtg cgaatgcagt gattgttgaa ggtgtccata tcggaaaaga tgcagtcgtg
     6601 gcagcaggag cagtggtttt agaagatgtg gcagcagaaa ctgttgtcgg tggaatacct
     6661 gcacgtgtat taaaaataag tgatgatcag acaaaagaaa atacagcatt gattgctgcg
     6721 ttacgcgaat tatagaggag atggagaaaa atgcgcgaaa tagatacctg tattgtgggg
     6781 gcaaccggat tagtcggcca aacgatgctc aaagtgttag aagaatatga ttttccagta
     6841 ggacgattga aattattagc ttcaaaacgt tcagccggta aagtttgtgt attcaagaaa
     6901 aagaaacaca ctgtacagga attgacagaa acttcatttg aaggatatga tttagcgcta
     6961 ttttctgcag gtgcttctgt atccaaagag tttgcgccaa tcgcacgaag tcagggacta
     7021 tttgtcatag ataattcctc agcatggcgg gaagattcgg atattccatt aatcgttcca
     7081 gaggtcaatc tggaagacta tacattgaat cggctgattg caaatccaaa ttgttcaacc
     7141 attcaagcgg tacttccgct taaagcttta caagaagcct ttggtatcca gcgagtcaat
     7201 tattcgacct atcaagcagt ttctggttcc gggcaaaaag gcattgaaga tcttcatcgt
     7261 acgcaaaatg acgagaaacc agttttgtat ccttataata ttagccaaac ggtgattccg
     7321 gaaatcgatc agcctttgga aaatgggtat acaaaagaag aacagaaaat gataaatgag
     7381 acccgtaaga ttctgcatca gcctgctttg ccagtatcag caacctgcgt acgtgtgcca
     7441 atcgaaaatg gacatggagt ctctgtggca gttcaactgc aaaaagagtt tacgacggaa
     7501 gaaattagag agtgtctcag ccagtttcca gggattcaat tagaagatga tctagcagca
     7561 cataaatatc cgacgagcat tcttgctaga ggaacagata tggtttatgt tgggaggatc
     7621 agaaaagaca cttctttaga gaacggattg ttgttctata cgactgccga taacatacgc
     7681 aaaggagccg ctgcgaatgc cgtacagatt gctgcagctt taatgcagaa aatagcggag
     7741 gtggcaagat gagtaatacg ctgaaagtag cgaaattcgg cggaacatcg atgtctcatg
     7801 aagagcaatt caaaaaagtc cgtacaattg ttctttcaga tcccaatcgc caagtgatcg
     7861 ttgtttctgc tttaggcaaa cgtacgtcag atgatgacaa agtaacagac ttactttatt
     7921 tgatttatgc ttaccttcag catcatgttg attggacacc cctttggaaa aggatttgtg
     7981 atcgtttcat tcaagtaaga gatgttcttg ccctgcagtt acctattgaa gatgaactag
     8041 cacgcataca gaaacaactg gaagacgaaa agataactga agattattta gtaagtagag
     8101 gtgaatatct gactgctcaa ctgatggctg agtatcttgg ttaccagttt attgacgcaa
     8161 aagacctgat tttctttgac tatgatggga aaatcgatca ggaaaaaaca gcacaggaaa
     8221 tcacaaaagc atttaaaaga tatccgaaaa tggttgttcc agggttttac ggggcgaacc
     8281 ctgcaggaaa agaaaaatta ttgggccgtg ggggaagcga cattaccggc gcgatactgg
     8341 cgaagatgtt gcaagcggaa agttatgaga attggacgga tgtttcagga atcatgatgg
     8401 ctgatccgcg aatcatcgat catcctaaaa tcatcgagga aatctctttt agagaactga
     8461 gagagatggc ttatatgggg gctaacgttc ttcatgaagc agctgttttc ccagttcaag
     8521 aggctgatat ccccatccaa ataaaaaata ccaatgatcc tttcgctcaa gggacaaaaa
     8581 tatcgaatca cgaaatagaa aaggaaaatg gactgacagg aatagctgga cgcaaggatt
     8641 ttctttccat cactttattc aaacgtcata tgtccgatga aatcgggttt atctggaaag
     8701 caatgagcat ttttgctaaa catgagatat caatcgaaca tattccttca gggatcgaca
     8761 atatcggagt gatcgtctca gcagaagcga ttgccgataa gttatttctc atcacgaaag
     8821 aattaaaaga aacacttggc gtggaagaaa tcgtcgtgat cgaagactta gctttgatct
     8881 ctgtcgttgg gggtccgcat aaagaattga ttggattatc tgggaaagtg ttatcgatat
     8941 tgaacaaatt agaaattcgc acatcgatct tatcacaagg agcacaggag ttgaatctga
     9001 tcatcggtgt accgaataat caatatgaaa cagtagtgaa gggtatctat gaagggatgg
     9061 tgaatacgga tgctgaaaga atatcgaatg gcactccatc aaattcctga aatcgggttt
     9121 catgaattca agacaaaaaa atatttatat gaacaagtaa aaaacagcga ggccgttatc
     9181 catgaaatcg gcgaaacagg actactcctt tattttgata atcagcaaga agaaacgatt
     9241 gcttttcgaa cagatatcga tgcactgcca gtcaaagaag aaacgaatct ctcttttgct
     9301 tctaagcatg aaggttatat gcatgcatgt ggtcatgacg gacatatggc gatgctttta
     9361 gggttgactg actttataac taaacacatt gaggatctta tttataatgt agtactgatc
     9421 tatcagccat cagaagaaat ttccggtggc gcacaaagcg ttattcagtc aggattgttg
     9481 gataaatatg aagtacaagc aatatttggc tttcatctat ggcctggact agctaaggga
     9541 gaagttttct ctcgaccagg acctttgatg gcacaaagca gtgaaacaga cattatcatt
     9601 aaaggccagt ctgcacatat tgcttctagt gaaaaaggaa tcgatagtct ggaggcagct
     9661 gtacgatttt tgaagaatgt ttatgatttt gaccggcaat taccggcaga gtggaatcat
     9721 ctaatgaaat ttggccaaat ccaaggtgga acgatccgaa atgttttagc tggagaagtt
     9781 attgtatccg gaagtatccg ttcttacagt tcagatatgc aaaattattt gaagagggga
     9841 ttagaccatt tagcagaaca gtttcactct acagctacta tttcttttcg ctataatgac
     9901 ggctatccag ctgtaatcaa ccatagaggc ttatatgcag cactgttaga ttcaaacaaa
     9961 ctacatgaat tagatgctcc agttcttcaa gccgaagatt ttggcatata tacgcaacaa
    10021 tatccatgtg tatttttctt tttaggtgtc ggtgataccc ctgctttaca tgatccgacg
    10081 ttcgattttg atatggatgt tttagaaaat ggtgtagaat ggtacaaaac gattcttttt
    10141 acagaaaatc ttcttgtaaa aatcgatagc agttcaaaag aggagcgagt aaataatgat
    10201 gaatttatcc aatcgattta gtcctaggct ttctagaata gaagtatcaa aaatacgaca
    10261 attcgatcag caaatatcgt cgataccaga tgtgatcaaa ctcaccctgg gagaaccgga
    10321 ttttccaact cctgaacatg tcaagcaagc aggaatagca gcgattgaag aagacttttc
    10381 tcactatacc ggaatgagag gattagagga actgcgggaa gcggcttgta tatttcagca
    10441 acagcgttat ggattaactt atgatccgca aacggaagtt ttgacgacag ttggtgcaac
    10501 ggaagcgatt gcctctgcgt tgttatctgt tttggaagaa ggagacaagg ttcttattcc
    10561 agcgcctgct tattcaggat atcagccatt agtggaacta gctggtgctg aattgatccc
    10621 gatagatact tctgacacag ggtttgtctg tcagccggaa caatttgaac gagcatttga
    10681 acaatatgga tcagctgtca aagcagtcat tttaaactat cctaacaatc ctactgggac
    10741 gacattgtct gcaaaacaat tgaaagcaat cgctgaggtt ttaaaaaaat atccggtatt
    10801 tgttataagt gatgaagtat atgctgaatt gacttatagt ggaacgcata tgtccatagc
    10861 tacttatctt ccagaacaaa caatcgtgat aagcgggtta tccaagtcac atgcgatgac
    10921 tggttggcga gtgggcttta tttttgctca aaaagccctt attgacgaac taattaaagt
    10981 ccatcaatat ctggtgactg ccgctacaac gatgtcgcaa aaagctgcgg ctgaagcgct
    11041 aataaatggg gtgaaagata gcgagaatat gaaagagcaa tatcaaacac gaagagacta
    11101 tctggtccag caattggcgc ctttaggatt tgaagtgacc cagccaaacg gtgcatttta
    11161 cttgttttgc aaactcccag ctgccattca aactgactct tggcagtttt gtgtagaatt
    11221 agcggaacag gcaaaagttg cgtgtatccc aggaattgca tttggcccag aaggagaagg
    11281 ttatatccgg atttcttatg ctagcagcat ggaaaaatta catgaggcct gcaaacggat
    11341 caaagacttt ttaacagaac agtgattcat agattttatc aaaaaaacaa tcgttaattt
    11401 tgcggtatat tctgcaagga gacgattgtt ttttaaattt agttcaaatg aacgcgtttc
    11461 ttttgattca taactaatgt aatgttaagt ttaaattgtt tagaatgatt ttaaaagaat
    11521 attcaaggag gtttcatcaa tggaaaaaat caaagttgtc attgtaggtg catctcatgg
    11581 agggcatcaa tcgatcttgg aactattgac acgatacggt gaaaatgtag atatcacgct
    11641 atttgaagca ggagactata tttccttcat gtcatgtggt atggagctgt atttagaaga
    11701 caaggtaaca gatgtaaatg atgtacgtaa tttcagacca gaaaactttc cgcaatccaa
    11761 tgttcatatt ttaaataatc acgaagtaaa aacgatcgat gccgataaaa aaacagtaac
    11821 ggttactagc gcatcagata acgaaacaaa agaatatcct tatgacaaat tgattttgag
    11881 ttctggtgtc aaaccaaaca atctgccagt accaggagca gatctagaaa atgtctactt
    11941 gatgcgtgga tacaattggg caaccaaaat caaagaaaaa ttaaatgatc cggctattaa
    12001 aaaaatcgct gtcgtaggtg cgggttacat tgggatcgaa gcagcagaag caagccgaaa
    12061 agctgggaaa gaagtcgtat tgcttgatgt gatcgataga cctttaggca cttatttaga
    12121 tgctgagatg acagatattt tagaacaaca cctaaatgaa aacggtattg aagttttgac
    12181 aaatgcaaaa atcgaagctt ttactggtaa cggaaaagtt gaggcaatca aaacaagtga
    12241 aaaagaaatc ccagcagatc tagtcattca agctgccggt gtgaaggcaa atacagaatg
    12301 gttaaaaggg atcgtcgact tagatgaacg tggctggatc caaacaaatg aatacttgca
    12361 aacgaatctt ccagatgtgt atgcagtagg agatgctaca cttgcttatt ctatcccagc
    12421 acgcaaaaaa atgccgatcg ctttagcgac tgttgcacgt agagaagcac gttatgtagt
    12481 aaaacatctt tttgaagaag taccaaacaa accgttcggc ggagtcgtag gttcctctgc
    12541 attaagtgtc tttgactatc attttgcagc aagcggattg aatagcttta cagcagcaaa
    12601 agcaggagta gatgtacgag tgtcttatta tgaagatacg ttacgaccaa aatatgtacc
    12661 agaagaacaa ggaaatccaa aagtgtccat ccaattattc tcggatccaa tgacccatca
    12721 attgctagga ggagcagtat tatctaccta tgatgttaca ggtcaaggaa atgtattggc
    12781 actagcgatc caaaacaaac tgactttaga agaactagca gaagctgact tcttcttcca
    12841 gccaggcttt gaccgacaat ggagcatgtt gaatctagcc gctcaacaag cgttaggaga
    12901 agaaccattt gtagaataag aaaacgaaat atttgaaaag aggttgtgaa aaagctgcct
    12961 tgcatcaagt aataagaaca gccaagtaaa aacagcttct tatgttttta acttggctgg
    13021 acttattacc gcagatgcaa gcttttgaac accgtttatt ttcaaaaaag ggactgtgac
    13081 acgatttgtg taccgacccc caaaagttag accaaaaaat ctaacttttg gaggtcggta
    13141 ttttttatgg ttaaatatac ttttgaactt aaattaaaga tcgttcatga ttatttggat
    13201 ggcaaaggcg attggaccgt aaaaatccag atcaagagat tgaagcggaa atgcttaaaa
    13261 ttcgggagaa gcacaaggat tatggctgtt tacggatgac caatgaacta agaaaccgcg
    13321 gtttctctat caataaaaag aaagttcagc gcttgatcaa gaagctagga ataaaagtaa
    13381 cggcatacac gcgtaaatca cgtcgctaca attcttatcg aggaaaagt
//
LOCUS       DAFBSV010000077        13333 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.078, whole genome shotgun sequence.
ACCESSION   DAFBSV010000077 DAFBSV010000000
VERSION     DAFBSV010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13333
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.078"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(178..735)
                     /gene="frr"
                     /locus_tag="LLB18_002164"
     CDS             complement(178..735)
                     /gene="frr"
                     /locus_tag="LLB18_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBK5245150.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(738..1460)
                     /locus_tag="LLB18_002165"
     CDS             complement(738..1460)
                     /locus_tag="LLB18_002165"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBK5245151.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1596..2477)
                     /locus_tag="LLB18_002166"
     CDS             complement(1596..2477)
                     /locus_tag="LLB18_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBK5245152.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2576..3358)
                     /gene="rpsB"
                     /locus_tag="LLB18_002167"
     CDS             complement(2576..3358)
                     /gene="rpsB"
                     /locus_tag="LLB18_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBK5245153.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3717..4196
                     /locus_tag="LLB18_002168"
     CDS             3717..4196
                     /locus_tag="LLB18_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HBK5245154.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4413..5504
                     /gene="phnW"
                     /locus_tag="LLB18_002169"
     CDS             4413..5504
                     /gene="phnW"
                     /locus_tag="LLB18_002169"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBK5245155.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5497..5625
                     /locus_tag="LLB18_002170"
     CDS             5497..5625
                     /locus_tag="LLB18_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBK5245156.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            5629..6174
                     /locus_tag="LLB18_002171"
     CDS             5629..6174
                     /locus_tag="LLB18_002171"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBK5245157.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6628..8319)
                     /locus_tag="LLB18_002172"
     CDS             complement(6628..8319)
                     /locus_tag="LLB18_002172"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBK5245158.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8739..9686)
                     /gene="arcC"
                     /locus_tag="LLB18_002173"
     CDS             complement(8739..9686)
                     /gene="arcC"
                     /locus_tag="LLB18_002173"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBK5245159.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9801..10820)
                     /gene="argF"
                     /locus_tag="LLB18_002174"
     CDS             complement(9801..10820)
                     /gene="argF"
                     /locus_tag="LLB18_002174"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBK5245160.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10911..12140)
                     /gene="arcA"
                     /locus_tag="LLB18_002175"
     CDS             complement(10911..12140)
                     /gene="arcA"
                     /locus_tag="LLB18_002175"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HBK5245161.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            12601..13302
                     /locus_tag="LLB18_002176"
     CDS             12601..13302
                     /locus_tag="LLB18_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBK5245162.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
BASE COUNT         3751 a         2710 c         2368 g         4504 t
ORIGIN      
        1 ttaaaagatt cccactatct taagtattat agcaatatct aactgttttt cctatgaaat
       61 cattgttttt ttatttaaaa actgaataat tttttctttt tttaattttt aaataaaaga
      121 aatataaata aaaacagagg aagcggaatg atccgcccct ctgtttttat gattttatta
      181 aacttccaat aattcttttt ctttatcagc agcgatctta tctacttctt tgatgctgtt
      241 atctgtcaat gtttgtacgt ctttttctaa tccgcgcaaa tcatcttcgg taatatcacc
      301 atttttttgt tgttttttat attcatcgat cgcatcacga cggatgttac gaatcgcgat
      361 ttttgcattt tctgcttctt ttttcacatc tttagctaat tcttttctgc gttcttctgt
      421 cagttgcggg ataactaagc gaatgacatt tccatcattg gttggactga ttccgatatc
      481 acttgccata atagcttttt caacatcttg aagaatgctc ttgtcaaaag gtgtgatcat
      541 taaaacacgt gcttctggaa tttggattga tgccatttgg ttcaatggtg ttggcgcacc
      601 gtagtagttc acagtaatac ggtccaaaag gctagcgttc gcacggcctg cgcggatttg
      661 cccaagttca cgttgaagat tttgtgctgc ttttttcatt ttttcttttg cttctgtcat
      721 aattgcatct gccattttta tttccccctt acagttgttc cgatattttc gcctaagatt
      781 gcacggcgaa tatttccgtg ttcatttaaa ttgaagacaa gcagtggaat atcattatcc
      841 atgcttagtg aacttgcagt tgaatccatg acttgtaatc ctttggcaat aacttccaga
      901 tgagtcagtt cttcaaattt tactgcattt gcatctactt tcggatcagc agaataaaca
      961 ccgtctacat tgtttttagc catcaggata acatctgcgc cgatttctgc cgcgcgtaat
     1021 gctgctgttg tgtctgtcga gaagtacggg ttgccggtac cgcctgcaaa gataacgatc
     1081 cgtccttttt ctaaatgacg ttctgcttta cggcgaatat atggctctgc gatttgacgc
     1141 atttcaatcg aagtttgcac gcgtgtcggt acacccacgt tttccaacgt atcctgtaaa
     1201 gctaaggcat tcataactgt agctaacata cccatgtaat cagcttgagc acgttccatg
     1261 cccatttgtg ctccgatttg tccgcgccag atatttccgc cgcccacaac gattgccatt
     1321 tcaacgccca gctcgtgaac ttctttgatt tcttggatga tttctttgat tactggtggt
     1381 ttgattccaa atcctgcgtc cccagctaaa gcttctccac tcaattttaa gactacacgc
     1441 tgatatttcg gtgtgaccat gttcattcct ccaatatttt ctattgccat tttaccatac
     1501 ttagatgatt tcgacactct aagactggtt tttcttgttt tgcttaaaaa aagggagcgc
     1561 acaaaccgtg cgttcccgtc tgttattcaa cagaattatt ttttcacttg gctcataact
     1621 tcttctacaa agttatcttc gcgtttttcg ataccttcgc caacttcgaa acgtacgaat
     1681 gttttaacag ttgcgccttt tgatgcaacg tatttttcaa cagtcatatc aggatcttta
     1741 acgaatggtt ggtccaccaa agcgatttct gctttgaatt tcttcaagcg tccttctacc
     1801 attttttcaa cgatattcgc tggtttgcct tcgttcaatg cttgttctgt aagaacagtt
     1861 ttttcatgtt ctaattcagc ttctggaatt tgtgattcgt ttacataacg aggattgata
     1921 gctgctacgt gcatagctac gtctcttgca actgtttcgt cagttgttcc atctagaaca
     1981 gtcaatacgg caatacgtcc gcccatatgc aagtatccac caaatgcagc attgtcgtct
     2041 ttttctacaa cttcaaagcg acggaagctg attttttctc cgataacttg agttgcttcg
     2101 atcaagtcag attcaattgt acctttatct gttttgattt tcattgcagc ttccatgtct
     2161 gctggtttgt tttcagcaac aagttctgca atttctttta ctaaatcttg gaacatttcg
     2221 tttttagaaa caaagtctgt ttctgagttt acttcaacga ttgctgcagt gttacctttc
     2281 acagcaactg aagccaatcc ttcagctgca atgcggtcat ttttcttcgc agcctttgcc
     2341 attccttttt cacgtaaaag atcaactgct ttttccatgt cgccttctac ttcaactaat
     2401 gcttttttcg catccatcat tcctacgcca gtcatttcgc gtagttcttt taccatttta
     2461 gctgtaacgt ctgccatgtt taactcctcc tgtgtgtttt tctttttaaa aaaagctgct
     2521 tcaaaggaga gtgaggcttg tcgcccagcc tttgaaacag ctccatcatt caaaattatt
     2581 ctgctgaaga attgtcgcct tcaacaacat ctacgatttc ttcgattgat gttgctgtgt
     2641 tttcttctgt gaaatcttct tcaactactt gatcttcacc ttggtttcct tcgatgaaag
     2701 catcagccat ttttgaagta atcaatttaa cggcacgaat tgcatcgtcg tttgaaggga
     2761 ttactacgtc gatttcatct ggatcgcagt ttgtatcaac catagctacg attgggatat
     2821 ttaatttgtg tgcttcttga acagcaatac gttctttacg tgggtcaacg atgtacatta
     2881 catctgggat tcttggcata tcagcgatac cgcctaagaa tttttcaaga cgttcacgtt
     2941 ctttgttcaa accagcaact tcttttttag gtagaacttc aaaagttcca tcttcttcca
     3001 ttgcattgat ttgtttcaaa cggctgatac gtttttggat agtatcccag tttgtcaatg
     3061 ttccgcctaa ccaacgatgg ttaacgaagt attgtcctgc acgagttgct tcttctttga
     3121 ttgcttcttg tgcttgtttt tttgtaccta cgaataatgc tacgccgcct tcttcagcaa
     3181 cgctcttcat gtaatcataa gctgcatcta ctaatttaac tgttttttgc aagtcaatga
     3241 tgtagattcc gtttctttct gtgaagatat atttcttcat ttttggattc cagcgacgag
     3301 tttggtgacc aaagtgtacg ccggcttcta gtaattgttt catagaaatt actgccatgt
     3361 ttgtttcctc cgatttggtt ttatttttcc tcttcttatc ttctaccttg ccggcaaact
     3421 ttttcaagca cctaccgaca atccaataag aatgtggatt tgctgatgca taaagcaccc
     3481 tcagctatta tacagacaaa agatccgtat cgcaagagca aatatacttt tctgctcaac
     3541 attcaatagt ttacctgaaa gataaaaaga attcaagaaa aacagtagat ttctctttgt
     3601 ttctttatta tcctttttcc ataaaataat tttaggtata aaagacgaat attattgggc
     3661 aatccttctt ttttttgtta tgatacatgt gaaatctttc gtaaaggaga aagaaaatgc
     3721 gcaaagctca aagacatttg ctgattaaac aagtcattga agaattcccg atccgtacgc
     3781 aagaagaact attaaacaaa cttgggcatt atggcgttac cgccacgcag gcaacgattt
     3841 ctcgagatat ccgtgatcta aaaatcgtga aggcacctga tgaaaatggc gtttcccgct
     3901 tcgtattgtt tcgcgaaaaa ggaactcctg agactaggac tgaggaagag gatcggctgg
     3961 ttcaaatgat tgaagacatt gtattgaaag tcgaacgagt ccactttttg acgatcgtca
     4021 ataccttgcc agacaatgct catttatttg catctgtttt agatgagatc aaacctccct
     4081 ctattgtcag tacaattgct ggattcgata cgatcatggt catctcggaa aatgaggagg
     4141 acgcaaaacg agtagaagaa tttcttcacc atccaactga agtatcactt ttttaatcag
     4201 agcacgtatt cctaatatgg aatgcgtgtt tttttatttt caatattttc cttattgaat
     4261 aaacctttac actctttaca aaaatacatc attttttatt caaatttttc aacaccttga
     4321 ttgaatcaca ataatcatca tttatattgg atgttaacaa gagcagcttc ttgctctttg
     4381 tgtatttcaa aaaagaaatg aaaggaaatc atatgtataa attattaact tctggaccat
     4441 tgacgacttc tgaaacagtg aaaaatgcta tgctgatcga tcattgtact tgggatcaag
     4501 aatacaaaga aattacacaa tggataagaa aaaaattatt ggatcttgct caagtatcgg
     4561 aaggaatata cacaacggtc ttaatgcaag gtagcagctc cttcggggta gaatcggtat
     4621 taagttctgt gatcaggcca gaagatactg tactgatttg ttcaaacggc gcatatagac
     4681 aacgaatgat caacatgtgc gaatgtctga aactgaacta taccgtttat gaggtatcgg
     4741 aacatcaaat cctccaagct catgtgatta cacagctgat tgaagagaat ccgtctatct
     4801 ccgcactagc aatggtccat agcgagacta cttccggtat tttgaataat ttggaagaga
     4861 ttgctgctgt cacacaagaa agagatcttt tgtttatagt ggacgcgatg tcaagctttg
     4921 gtgggatacc gatttgtgta gccgaactag ggattgattt tttgatttcc agctcaaaca
     4981 aatgtattca aggtgttcca ggcttttctt ttgtacttgc taataaagcg gaactggaaa
     5041 aacgaaaaaa tgttagccga agtttgtcac ttgatctata tgaccagtac cgcgtgatgg
     5101 aaaacgagaa tggcaaatgg cgtttcactt cccctaccca tacggttttg gcttttcaac
     5161 aagcgctgaa ggaactagag gcagaaggag gaatcgaaac tcgatattca cgttatctcg
     5221 ccaataatca tgtgctacga caaaaaatga cagagatggg gttccagcct ttcattcaag
     5281 aatatcaggg gccattcatc acctcttttc tttaccctaa ggactggcga tttgatttta
     5341 atcattttta tcagtattta aagcaaaatg gatttgtgat ctatcccggg aaaatcagcg
     5401 atcatgaatg ttttcgtatc ggaaatattg gcgagatcta tccggaagat attttggaac
     5461 tgacagcaat tatcaaagac tataaggaga acgttaatga ttaaaactgt aatttttgat
     5521 tgggcaggaa caactgtgga ctttggctgt atggctcctg tccacgcttt tagaaatgct
     5581 tttctagaaa aaggaatcca actgactgac aaagaaatcc gctaaccgat gggaaaatta
     5641 aaatgggatc atatccaaca gcttctttcc ctcccttctg tcaaaaaaca atggatagct
     5701 atttatggac aactacctca ggaaaaagag gtggaggaat tgtatcaaca atttgaacat
     5761 tatctgttta aagatttggt caagcattct accttgaaac ccgacacatt ggaaacgatc
     5821 gaacggttga gaaacgctgg gatcaatatt ggttccacga atggatttaa tgctcctatg
     5881 atgacaatcg tagcagaaac cgcaaaaaaa gaaaggtatt caccagactt catggcaact
     5941 tttgaagacg tcgaagggta tggtcgaccg tttccttata tgatccataa aaacatgcag
     6001 tacttcaaaa acaagtcggt tgatgaagta atcaaagtcg gagatacggt ctcagatatc
     6061 caggaaggga aaaatgccgg agtgttgaca gtaggtgtaa ttgaaggtag ttcgctaatg
     6121 gggatttctt atgatgagta ccaaaaatta gagatgggga aaaagatcgt ttaaaacagt
     6181 ctgttgctct tagattccaa caagccggcg ctgatatttg tgtaaacaat ttaaaagagt
     6241 taacagaata cattttgtac gctgacaaga atccagaatg acttttatac aaaataagag
     6301 gttgtgaaaa agctgtcctg tatcaagtaa taaaaacagc caagcaaaaa tagctcctca
     6361 tatttttcgt ttggttaggc ttattaccgc agatgcaagc ttttgaacac cgtttattcg
     6421 aaaaaaaaaa gggagctgtg acacgacttt tgtcacagtc cccttatttg caaacaaaca
     6481 gtgtttaaga gacaacctct ccactaaacg gtgttcattc agctgactct cggtatttgc
     6541 tcaaaaaacg ataaaatttg aaaagctatt ttctcttttg tttctctaat actcggatca
     6601 gaacgctgat ttcacattct ctttttctta catcttatct ggtgcatgaa gtcctagcaa
     6661 acgaaggtct tctttcaata atacagtcac tgcataaact agagctaagc gtgcttcttt
     6721 ttgttcatca tcagctaaaa tcttcgtatg agcatagtat ttgttgaatg cttgtgctaa
     6781 tttgattgca tgtttcgcaa tcactgacgg ttcgtatttt tccccagcag acaagaccgt
     6841 ttcagggtat ttttgaacta atttaaccac ttcccagctg gtatcgtcat tcaatgcata
     6901 gtctgctgtt tctgaaggga caaatcctgc tttttccaac aggctgactg cacgagcatg
     6961 tgtatattgc acataaggtc cagtttctcc ttcaaatcga acaacttctt ccaggttaaa
     7021 gtcaaatgta ttcagtcgat cgtttttcaa atcgtggaaa atgactgccc caaccccaac
     7081 ttgtttagct acagcatctt tgttttccaa atcagggttt ttctcgctga tttgttcttt
     7141 agcagattgg attgcttcat ttaatacttc ttctaataag acgatctttc ctttacgagt
     7201 tgataatttt ttaccacctt gcgtgatcaa accaaatgga atatggtgca tgtcgtcaga
     7261 ccagtcaaag cccatttcct tcaagacagc tttcaactgt ttaaaatgat agctttgttc
     7321 attccctact acatatagag attgtttgaa gtcgtaagta cgtttacggt acaatgcagc
     7381 agctaagtca cgtgtaatgt atagtgtcgc accgtctgac ttcttaatca acgctggatt
     7441 caggtcataa gcagataggt caacgatctc tgcaccttta tcctcgttca gcaaatgttt
     7501 ttcttctaaa agtttgacga tttcatccat cttgtcattg tagaaagctt caccgttcaa
     7561 cgaatcgaaa cgtacttcca gcagatcata gattttattg aattctttca tcgattcatc
     7621 acggaaccat tgccataatt gaatagcctc tttatcgcct tcttccagac gtttgaacca
     7681 agcacgagct tcttcattta attctggttc tgtttcagct acttcatgga attggacgta
     7741 taaacgaagc aattcattga ttggttctgc tttaacagct tcttctgtac cccatttttt
     7801 gtaagcgacg atcagttttc caaactgtgt tccccagtca cctaaatggt tgatgcggat
     7861 tggctgataa ccgatttttt ccataatgaa accgatcgaa ttaccgataa ctgtcgaacg
     7921 caaatgtccc attgagattg gtttggcaat attaggagaa gacatgtcga ttggtactgt
     7981 tccttgattc ccgatgttgc tatccccata atgttctttt tctttcacta cggtttgcaa
     8041 aacttttttg ctgataagtt ctttattcat gaaaaagttc aagtaaggtc cgacaacttc
     8101 gattttttca aagttggcag aatcgatttt ttctgctaaa tctgcagcga tttgctgtgg
     8161 cgcttttcgg taaacttttg ctaatgaaaa ggctggaaat gcaacatctc cgtgttcagc
     8221 tgattttgga ttttctagta attgctcgac ttgttccagt gttaaatcat ctttgacagc
     8281 gtcatagaca gcttttgcga caagatcttt attattcatc tttattcctc ctaaagtgtt
     8341 cccttgattg ttaaacaaaa aaaatctcta gcgacggcat acttagtatg ccatcactag
     8401 agacgagatt tcccgcggta ccactccaat tgtcctaaaa aaggaccagc tccatctgat
     8461 atcggtagac gaccgtctgt ttaaaacaga attctccaag tgcgcttcgt tgtatcttct
     8521 tcattcggct tccaccactt ccgaattcgc tagccaagaa tgatacaagt actctcttgt
     8581 tcaacaaatc ttagtcttat taaactttct tgaattatat cagaaaaaaa aacgaaaggc
     8641 tagtcgtttc ataaaaaaaa aatccagatg gcctaaagga gaagaaatac cacctggata
     8701 gctataaatc atttcgtaaa tacgaaagac ttaacaaatt aatcagctac gataatcgtt
     8761 ccttcttcag aagctaaaag attctcgata ttttctaaag aagtgatgat tgccttagcg
     8821 tttggttttg cttcaacaaa tgcaatagct gcttctactt tcggaagcat gcttcctgga
     8881 gcgaattgct tttcatcaat gtattgtttc atttctgaaa cagtaacagt ttctaatttc
     8941 ttttgatctg gtttttggta attgacatac acattgtcta ctcctgtcaa tacgatcagc
     9001 aaatccgcat cgatgatttc ggctaatttt tctgaagcaa aatctttatc gattacggct
     9061 tctcgtcctt ctaatccagt agctgtttct acaacaggaa tcccaccgcc accaacagag
     9121 actgtgataa ctccttgatc gaccagcgtt tcgatgacac gtgcttcttt aatcgagatg
     9181 ggtttagggg aagcgactac ttttctccat ccacgtccag catcttcttt gaatgtcaca
     9241 gtggagtcag cattcatttg ttctttggct tcttcttccg tgtagaatgg accgactggt
     9301 ttacttggat ttttgaatga aggatcattt tcatccacaa taacttgagt gactaaagaa
     9361 accacatctt tatcgatccc tttttccttc agtacttcgc ccatggcgtt ttgtaaccag
     9421 taaccgatag atccttctgt cattgcaaca catgtatcta aaggcattgc cggtgttttc
     9481 tcagaatcag cagcttgctg ctgaatcaat aggttaccga cttgcggacc atttccgtgg
     9541 gagatgatca attcatctcc ttgttcgata aatttcacta aatactttgc tgtttccatt
     9601 aacgcttctt gttgggcttt tgcacttgca tccgtagaca agatggcatt gccccctaaa
     9661 gcgacaacta cttttcgttt ggccatttca ttcgtccttt cttcagttct accgaatttt
     9721 ctagataaca aaacgagcca gcgttttgtg attttccctc aatgctgact cgttttttcg
     9781 tgagatgaat gtggttatgc ttaaacgcga gggataaaca agttacctaa tgttgctgcc
     9841 atgatcgctt tgattgagtg catacgattt tctgcttggt caaattgacg agcatatttg
     9901 ctgcggaaga cttcatctgt tacttccatt tcagtgatgc caaagcgttc tttcatttgt
     9961 tcaccgtaaa cagtgtttgt atcatggaaa gctggcaagc agtgcaagaa gatcaaacga
    10021 tctgtgttgt gtgttttttc taccatttcc atattgattt ggtaaggttt caacaatttg
    10081 atacgttctt cgaatttatc ttcttcaccc attgataccc atacatcaga ataaaggacg
    10141 tctgctccgt ctacaccttt atcaacatcg tcggtaatca tcaattgtgc accggatttt
    10201 tcagcaaagc cttctgccat tttgacgatt tcttcttcag gttgtaattc ttttggtgca
    10261 acgatacgca tattcgctcc taaaattgca cctgtgacta ataaagagtt agccatattg
    10321 tttcgaccat ctccgcagta agcaacagtg ataccttcta ctgttccaaa gttttcttgg
    10381 atagttaaaa agtcagcgat catttgtgtt ggatgccatt catcagtcaa gccattccaa
    10441 actggaacac cagagaattc tgctagttcc tctaccattt tttgactgaa tccacggaat
    10501 tcgattccgt caaacatacg tcctagtact ttagctgtat cttctgtgga ttctttttta
    10561 cctaattgga tatcatttgc acctagatat tcaggatgtg cacctagatc gatcgctgca
    10621 gtagtaaatg cagaacgagt acgtgtagat gttttttcaa ataaaagcgc aatatttttt
    10681 ccttctagat agtgatgtgg gataccacgt tttttcaagt ctttcaagtg ttctgaaaaa
    10741 tcgatcaaat attgtaattc ttcttttgta aagtcttttt ctgctaataa gcttcttcct
    10801 tggaatactg attctttcat attaaacatt ctcctttaga ttgtttttat ttaagattaa
    10861 agaggaaatc ccgacggcag ctgacagtaa gactgccgtc aggaaacaaa ttacttcaag
    10921 tcttcacgga caagtggttg gctcatgcag cgtggaccac cacgacctcg tgacaattca
    10981 cttgaattga tttctaacac tttgatgcca tagctacgaa gcaattcgtt cgatacataa
    11041 tttcggttat aagtgactac aacacctgga gcgattgcca atgtgtttga tccatcattc
    11101 cattgttctc gaggtgcaac gatctcatct ccattaccag ttgggatcag tacaagatca
    11161 tctaatccaa gagcagcttt catcgtttcg tgtaagttat ctgaatgagt aatcttgata
    11221 tcatcaccat ctggttcgat tgtaaagaca tccatcttac cgtctttact ttgaattgct
    11281 ggatggatag tgaatttatc gtgatctacc attgtaaata cggtatccaa atgcatcatt
    11341 gcacggttgt tcggaatttt gattgccaac actttttcaa atcctgaatt ttttgcgaat
    11401 aggtggcgtg ctaatttttc taaagctttc gcattagttc gttgagaaat cccaacagct
    11461 actactttat cgcttaagat caattcgtct ccgccttcga tatgatctgg attttcacga
    11521 tccaaccata cttcgattcc tttatttgca aatcttggat gatgtttcaa aatatattct
    11581 gtaaacatcg attcacgacg acgtgcttca aaagtcatct tattgactgt catcccattt
    11641 cccattgatg cggaagggtc gcgtgtaaag tacaagtttg gcattgggtc catgtaaaat
    11701 ggatagtcat cgtctgctga cagatcatat agactgctag aacgtacttc gatatctttt
    11761 gtacgaaccc cagccatgat tttatctacc atttcttgcg tttccattga tagaaggaac
    11821 tcatgaagac cctctcttac agcattcgat gcaatatgag attcatccaa cattttattc
    11881 aagaattgtt ctttgacatt gcctgcgtca atcgcttctg ccgctaattt ttccaagtaa
    11941 agagtctcga cgccttcatt ttgcaatgtc ttcgcaaagt tgtcatgttc ttcttgagca
    12001 atcggaagat atggaatatc atcgaacaac agacgatcca taatatctgg tgtcaaattt
    12061 tccacttctt gtccaggccg tttcagtaaa actgtcttta atttccctat ttcagagaaa
    12121 acgtgaatag gtttatccat gttgtgttgc ctccttcttt ttgattacat gtataggata
    12181 tcctcctttt gtaatcactt tcataatttt gtctcattca aaatgagaca ttcctcacat
    12241 taatattcga taattaaata attaaacgtt tttctatttt taagcgtaat ttattcattt
    12301 tttattctgt atacactttc aaaaaaatat ttattcattg aaaaaatttt tttgaataaa
    12361 ttaaaaaaat aaattatatt atcgttgtta gcgtttacta tatgtattat tgttgttttt
    12421 tatacacaaa tcattcgctt caaaacaaat tattcaatac cattgtatat tttttacata
    12481 ataacaaatt atatttgtaa agtattaaaa cttgtttcta atgttggtat gttaaaactt
    12541 tacaaattct ttaaaaaaag tgacaataaa tatagtgaac aataaggaga ggacttttta
    12601 atgcgtgtta ataaaatcga ttttcacttt tcaaaactca gatatcaacc tgattttgaa
    12661 catttctcgg atgaagagtt ccaacagatc aaggaacata ctgttcttcg ttcttataaa
    12721 aaaggacaga tccttttcga cgatggtgat cccagacaac ggttgtatat cttgaccaaa
    12781 ggactcgttc gtttagaacg ttatgatgaa agtgcaactt attactacta tgactatgtg
    12841 aatacaaata acctttttcc tatgtcagga atgtttggag aagagaccta cacttataca
    12901 gctcaagcga tgactgatat tgaaacattc taccttcctg tttcctacta tgaaaaatta
    12961 gcacgaaaaa atcccgaaca gttgatctat atgatacaaa aaatttctaa agtagttgaa
    13021 atacatgaat tgcgtatcca aatcggattg acctctagcg cctttgaccg ggtaaaacaa
    13081 aatttattca ttttgaaaga agaattgggc gtaccaacaa aagatggtca tatcaccatt
    13141 ccttatccga tcaccttaaa agaattagca gtgaatagcg gcacgacacg tgaaactgct
    13201 ggacaagtaa tcaaacaact acgtgattcc gggctgttag attatgacaa aaagcgtttt
    13261 actttctgta agacagctac tactccagct atgagagaat aacgcgaaca aaaataagca
    13321 gtgaccctga taa
//
LOCUS       DAFBSV010000078        13049 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.079, whole genome shotgun sequence.
ACCESSION   DAFBSV010000078 DAFBSV010000000
VERSION     DAFBSV010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13049
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.079"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(77..149)
                     /locus_tag="LLB18_002177"
     tRNA            complement(77..149)
                     /locus_tag="LLB18_002177"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
     gene            530..1099
                     /locus_tag="LLB18_002178"
     CDS             530..1099
                     /locus_tag="LLB18_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBK5245163.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1086..1946
                     /locus_tag="LLB18_002179"
     CDS             1086..1946
                     /locus_tag="LLB18_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBK5245164.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2136..2840
                     /locus_tag="LLB18_002180"
     CDS             2136..2840
                     /locus_tag="LLB18_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5245165.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2845..4680
                     /gene="walK"
                     /locus_tag="LLB18_002181"
     CDS             2845..4680
                     /gene="walK"
                     /locus_tag="LLB18_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HBK5245166.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4677..5993
                     /locus_tag="LLB18_002182"
     CDS             4677..5993
                     /locus_tag="LLB18_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245167.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5994..6863
                     /locus_tag="LLB18_002183"
     CDS             5994..6863
                     /locus_tag="LLB18_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HBK5245168.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6918..7727
                     /locus_tag="LLB18_002184"
     CDS             6918..7727
                     /locus_tag="LLB18_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBK5245169.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7830..8459)
                     /locus_tag="LLB18_002185"
     CDS             complement(7830..8459)
                     /locus_tag="LLB18_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HBK5245170.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8629..9921
                     /locus_tag="LLB18_002186"
     CDS             8629..9921
                     /locus_tag="LLB18_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK5245171.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9997..10659)
                     /locus_tag="LLB18_002187"
     CDS             complement(9997..10659)
                     /locus_tag="LLB18_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBK5245172.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10884..11168
                     /gene="groES"
                     /locus_tag="LLB18_002188"
     CDS             10884..11168
                     /gene="groES"
                     /locus_tag="LLB18_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBK5245173.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11219..12844
                     /gene="groL"
                     /locus_tag="LLB18_002189"
     CDS             11219..12844
                     /gene="groL"
                     /locus_tag="LLB18_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBK5245174.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4338 a         2254 c         2824 g         3633 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      541 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      601 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      661 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      721 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      781 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      841 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      901 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      961 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
     1021 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
     1081 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1141 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1201 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1261 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1321 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1381 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1441 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1501 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1561 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1621 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1681 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1741 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1801 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1861 tctactttgg ccagatttct ccggcattag tagtccacac tggtccggga ttattgggtg
     1921 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1981 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     2041 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     2101 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2161 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2221 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2281 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2341 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2401 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2461 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2521 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2581 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2641 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2701 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2761 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2821 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2881 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2941 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     3001 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     3061 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3121 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3181 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3241 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3301 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3361 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3421 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3481 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3541 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3601 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3661 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3721 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3781 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3841 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3901 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3961 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     4021 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     4081 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4141 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4201 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4261 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4321 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4381 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4441 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4501 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4561 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4621 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4681 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4741 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4801 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4861 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4921 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4981 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     5041 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     5101 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5161 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5221 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5281 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5341 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5401 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5461 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5521 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5581 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5641 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5701 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5761 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5821 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5881 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5941 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     6001 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     6061 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6121 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6181 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6241 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6301 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6361 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6421 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6481 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6541 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6601 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6661 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6721 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6781 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6841 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6901 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6961 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     7021 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     7081 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7141 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7201 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7261 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7321 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7381 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7441 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7501 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7561 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7621 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7681 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7741 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7801 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7861 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7921 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7981 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     8041 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     8101 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8161 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8221 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8281 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8341 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8401 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8461 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8521 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8581 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8641 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8701 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8761 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8821 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8881 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8941 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     9001 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatgca
     9061 cgtttagtaa gacttgcgaa agggtggaag caaagagaga agatacctga aaatgtttgg
     9121 cagtctttta cttcattgat tccaatcatt gttatagtca cttttacgct tatcggttca
     9181 gcggtttttc aacagttgtt cagaatgact gttgttcaag gagtatggac atatgtccag
     9241 cttcccattc aatcgttcat agacacgttg tttggtgtgc ttttattagg tttttttgtt
     9301 ccgtttttat ggttatttgg tcttcatgga tctgcgatgg tcaatgggtt ggttagtccc
     9361 gtcttgcaag cgaattcatt agcgaatgca gaaatcttag cctcaggaca agagttgacg
     9421 gtggcaaatg gcggacatat cgttactcag caatttctcg atcagttcat gacggttacg
     9481 ggtgctggat tgacgttagg ggctgtattt tttatgacgg tttttgcgaa atcgaagaaa
     9541 tacagagaat taggaaatct tgctctttta ccagcctttt tcaacatcaa tgaatcaatt
     9601 attttttcca caccgatcgt gatgaacccg atgatggctg ttccttttat tttcgcaccg
     9661 gtcgtttcag gattgattac ctattccgct ttatattttg gattcgttcc tttatttaca
     9721 gcagtccaag tcccttggac aacaccgccg atcctctcgg gtttcttagt aggcggagtg
     9781 cctgcagcga ttttacaagg tatcgtgttg tcaattagtt ttttcattta tttcccattt
     9841 ttgaaaaaaa tagattctgc aaactgcaaa aaggaaagac agacaaaaaa tgatggagca
     9901 gcagaaaaga tgaacgacta aaaaacaaaa atactcctgt cgctttagat tgggaaaatc
     9961 accaatctag gatgacagga gtatttatag tcatgtttat actagccctt tttggacagc
    10021 taattgaaca agaacaacta atgtgttcat tcctacgtgt gtgatcatcg atgtccagat
    10081 ccgaccagtt gctttgtact ctaggctgaa gaagaaacct aggaaaaagt agattagcag
    10141 atgaccatca ttatgagcaa acgcaaacag caaagagctg atcactgctc cgacccaaaa
    10201 atttgaatat cgactgatga tccccagtat actgcggcgg aatacgaact cttccatgat
    10261 gggtccagca acagttgtcg ccaaaataaa agcgggtgct tccatgatca tctggatgat
    10321 attttgtgta ttctcggaag gggttgcttt gccaaacaat acagattcta acatgacagc
    10381 gatgctttgc agaatcaatg cgacaaagat tccaaccaat ccataaataa caatctttgg
    10441 agcagaagct ttttttaccg ctgattcgat cgctaagggt tcacgttgct taaaataaaa
    10501 aatagctagg acaacggcgc ctagtatata catgactgca gttgctgtga tcaattcaga
    10561 cgtagatttt acaagtccta tcgaagctag gatcaagggt gagataaaaa ttagaccata
    10621 gcaaaaaatg ctgaggaagc tatatttttt taaagacatg taattcctcc ttttaaggga
    10681 taacaagcat gcaaggcaag cttatatcga ttgatttcaa ttatatcata atttcaataa
    10741 gcagctgtca gaataaaatt tcttttcttt gatttaaaag cttgcaaaaa agagggagaa
    10801 tgagtattat taaaaatgta ggttagcact cgaaggttaa gagtgctaac agattaaaaa
    10861 aagagttatc ggagggattt atcgtgttaa aaccattagg tgatcgcgtc attatcgaag
    10921 tcgcaaaaga agaagaaaaa actgtcggag gaatcgtttt agcttctgct gctaaagaga
    10981 aaccccaaac tgggacagtt gttgcagtcg gtgaaggccg tttgttagaa aacggtgaaa
    11041 aagttcctgc cgctgtaaaa gcaggcgacc aagttatgtt cgaaaaatac gccggtacag
    11101 aagtaaaata cgaaggaaaa gaatatctga tcgtcgcagg aaaagatatc atggcgattg
    11161 ttgagtaaat ttggaagata aaaaaataat caaaaataat caatgaggtg aatcaatcat
    11221 ggcaaaagaa ttgaaatttg cagaagacgc acgcgcagct atgttacgcg gggtagataa
    11281 attagcagat acagtgaaag taacattagg acctaaaggc cgaaatgtcg tactagaaaa
    11341 atcttacggc tctccattga tcacaaatga tggtgtgacg atcgcaaaag aaatcgaatt
    11401 agaagatcat tttgaaaaca tgggtgcaaa acttgtatca gaagtagcat caaaaacaaa
    11461 tgatattgca ggagacggta caacgacagc aactgttctg acacaagcaa tcgttcgcga
    11521 aggtttaaaa aacgtaactg caggtgctaa tcctctaggc attcgtcgcg ggatcgaatt
    11581 ggcaacaaaa gcagcagtcg aagaattgca taatatctca actgttgttg attcaaaaga
    11641 agccattgca caagtagcag ctgtttcttc gggttctgat aaagttggac atttgattgc
    11701 tgatgcaatg gaaaaagttg gaaacgacgg tgtcatcaca atcgaagaat caaaagggat
    11761 cgaaacagaa ctagatgttg tagaaggtat gcagtttgat cgtggttact tatcacaata
    11821 tatggtaaca gataacgaca aaatggaagc tgttctagaa aacccatata tcttgatcac
    11881 agacaaaaaa atctctaaca tccaagatat tctgccattg ttagaacaaa tcttgcaaca
    11941 atcacgtcca ttgttgatta ttgctgacga tgtagatggt gaagcattgc caactcttgt
    12001 attgaacaaa atccgtggaa cattcaacgt agtagctgta aaagctcctg gtttcggcga
    12061 tcgtcgtaaa gcaatgcttg aagatatcgc tattttgaca ggtggtacag taattactga
    12121 cgatctaggt ttagaattga aagatgtaac aatcgaaaac ttaggaaatg cttctaaagt
    12181 tgttgtagat aaagacaata caacgatcgt agaaggttct ggagaaaaag aagcaatcga
    12241 agctcgtgtg caattgatca aaaaccaaat tgctgaaaca acttctgatt ttgaccgcga
    12301 aaaattacaa gaacgcttag ctaaattagc aggtggtgta gctgttgtta aagttggtgc
    12361 agctactgaa acagaattga aagaattaaa attacgcatt gaagatgcat tgaatgctac
    12421 acgtgccgca gtagaagaag gaatggtctc aggtggtggt acagctctag tgaacgttat
    12481 cagcaaagtt tctgctgtag aagcagaagg agacgtggca acaggtatca agatcgttgt
    12541 tcgtgcttta gaagaaccaa ttcgtcaaat cgctgaaaac gctggttatg aaggatcagt
    12601 gattgttgat aaattgaaga acgtggaact aggcactggt ttcaatgctg ctactggaga
    12661 atgggtaaac atggttgaag caggtatcgt agacccaact aaagtaacac gttctgcctt
    12721 gcaaaatgcc gcttccgttt ctgccttgtt attaacgaca gaagcagtcg ttgcagataa
    12781 accagaacca gcagcgccag cagctcctgc aatggatcca tcaatgatgg gcggtatgat
    12841 gtaagaaaaa gcaacttgct tatctacaac tgatcattag tgaaagacag ataaaaagag
    12901 gctggaacag aagcgtttaa ctccaagaaa taagaagaaa ttcacggaaa ttgcttttca
    12961 aatttttgtg aatttcagct tatttccgaa ggagttgctt ctgcttccgc tgtttatacg
    13021 tgtttagagc gtgagacaaa agtgttctt
//
LOCUS       DAFBSV010000079        12949 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.080, whole genome shotgun sequence.
ACCESSION   DAFBSV010000079 DAFBSV010000000
VERSION     DAFBSV010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12949
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.080"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            66..767
                     /locus_tag="LLB18_002190"
     CDS             66..767
                     /locus_tag="LLB18_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HBK5245175.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            764..1885
                     /locus_tag="LLB18_002191"
     CDS             764..1885
                     /locus_tag="LLB18_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBK5245176.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            1900..3132
                     /gene="pepT"
                     /locus_tag="LLB18_002192"
     CDS             1900..3132
                     /gene="pepT"
                     /locus_tag="LLB18_002192"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBK5245177.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            3264..4172
                     /locus_tag="LLB18_002193"
     CDS             3264..4172
                     /locus_tag="LLB18_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBK5245178.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            4207..4479
                     /locus_tag="LLB18_002194"
     CDS             4207..4479
                     /locus_tag="LLB18_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBK5245179.1"
                     /translation="MDVLLHNLLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            4490..5536
                     /locus_tag="LLB18_002195"
     CDS             4490..5536
                     /locus_tag="LLB18_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBK5245180.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            5787..8396
                     /gene="clpB"
                     /locus_tag="LLB18_002196"
     CDS             5787..8396
                     /gene="clpB"
                     /locus_tag="LLB18_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBK5245181.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQPNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(8547..9233)
                     /locus_tag="LLB18_002197"
     CDS             complement(8547..9233)
                     /locus_tag="LLB18_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245182.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(9211..9705)
                     /locus_tag="LLB18_002198"
     CDS             complement(9211..9705)
                     /locus_tag="LLB18_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBK5245183.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(9725..10945)
                     /locus_tag="LLB18_002199"
     CDS             complement(9725..10945)
                     /locus_tag="LLB18_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5245184.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            11092..12927
                     /gene="lepA"
                     /locus_tag="LLB18_002200"
     CDS             11092..12927
                     /gene="lepA"
                     /locus_tag="LLB18_002200"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBK5245185.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
BASE COUNT         4242 a         2368 c         2716 g         3623 t
ORIGIN      
        1 ttttttattc ctagtctcct tattttattt ggaaaatgct ataattatct agaaggagtg
       61 aagctatgaa ccatttagat ttatctcagc gcttagccgc agtgggtgac tttgtccctg
      121 aatccgctcg tttagcagac attggatcag atcacgctta cttacccgtt gcattgatat
      181 taagaggaaa aatcgaatat gcagttgctg gtgaagtcgt tcaaggtcct tatgaatcag
      241 cacgtaagca agtcaaaaaa gatggattag aagaccgtat caccgtacgc cttgcaaatg
      301 gtctagatgc tatccagcca caagatggta ttacagctgt cacgattgcg ggtatgggag
      361 gttcactgat ccgagatatc ctagaagctg gcaagttgaa tcaacgctta agcggacaag
      421 aacgtttgat ccttcagcca aacatcggag agcgtacatt acgatcttgg ctgcaagaaa
      481 atcagtataa aatccaatca gaaaaaatac ttgaagaaaa taaaaaaata tatgaaatca
      541 ttgtagccga aaaagaacaa aaaccagtta cttacaatga aatggagctg atgttcgggc
      601 catttctgct tgaagagaaa agtgagatct tcaaatcaaa atggacaaga gagcttcaac
      661 aaagaaaagc tatccgtgaa cagctcaaac aagcagctaa tcaagaggca cgtcaaaaac
      721 aaatcgagca ggaaatccaa atgattgagg aggttttaaa gccatgacaa tcagcggacg
      781 cactttcatc caaaagtttg aaagctattg tcctcagtgg ctagctgaag aaggagaccc
      841 agtcggactg catatcggaa cattggataa gccaatccaa cgagtaatga tgacattaga
      901 cgttcgtcca gaagtggtcg aagaagcaat caagaaaaaa atcgatttgc tgattgctaa
      961 acatcctcca atctttcgtc ctgtaaaacg gctggttact gatcagccac aagaaaaaat
     1021 gtatgcagat ttgttgaaac atgatattgc cgtctatgca gcacacacga acatggatat
     1081 tatttgggat ggactgaatg actggttttg tgaacttctc ggtattgaag tggagagtta
     1141 tttagtaaag actcatgaga ttcattataa aaaactggcc gtttatgtac ctgtggatca
     1201 tgcacagaaa atgcgtgaag tattagctgc agctggtgct ggtacacaag gtgattatac
     1261 cggtacaagt tttacctcga ttggacacgg tcgatttact ccggaagctg gtgcacaacc
     1321 agcgattggg aaagtaggga agacagaaca agttcaagag gcaaaagttg aggttatttt
     1381 gccggaaact atcgaaaaac aagtgattca agccatgcgg tcagctcatc cttatgagga
     1441 acctgcttat gatcttttcg ctatagatga accagtcgaa atgtttgggt taggacgagt
     1501 aggtgaattg ccgcaagaaa tttctataga ggcatttgta gaacaagtaa aagaagcgtt
     1561 ccaactagat ggactgagaa tagtccagcc aaaaaatgca aaatcctctg tgaagcgcat
     1621 tgcgatttgc ggtggaagcg gtgaaaaatt ttatccgcaa gcaatcgccc aaagagcaga
     1681 tgtctatatc acgggagata tctattatca tacggctcat gatatgcaaa gcgctgggtt
     1741 gattgcaatt gatcccggtc attatattga atcgttatgc aagcaacgat ttatcgagaa
     1801 atttgaatct tggaaacaag aagaaaattg ggatattaac tttttcgttt ctgaaacaaa
     1861 tacaaaccca tttcaattta attaaaagga gagaatacta tgtacgaaaa tcttttgcca
     1921 cgttttttac gatatgtcaa aacagaaaca cgctccgatg caacaagcaa aacgactcca
     1981 tcgactcaga cacaagttgc ttttgcgcaa gaattgaaaa aagaattaga agagttaggc
     2041 ttagctgatg ttttctataa tgaagataac ggattcgtta tgggaacatt accaagcaat
     2101 gttgatcatg aagtgcgttc cattggattt atttcccaca tggatacagc agattttaat
     2161 gcagtaggag tcaatccaca aatcattgaa aactatgatg gcgagtctac gatcgtacta
     2221 gatgcggaag aacgctatac attgaataca aaagattttc caaatttgaa aaattatgaa
     2281 ggccacacat tgatcacaac agatggcagt acattactgg gagcagatga caaatcaggg
     2341 attgcggaaa tcatgactgc aatggagatc ttgatcaata atccttctat ccctcacggt
     2401 accatcaaag tggcttttgg tcctgatgaa gaaatcggtg tcggagcgga taaattcgat
     2461 gttgagcaat tcgatgtaga ttttgcttat acagtcgatg gtggtccttt aggtgagttg
     2521 cagtatgaaa cgtttagtgc tgctcaagca aatattacga tccaagggaa aaatgtacat
     2581 ccagggacgg caaaagatac aatgatcaat gctctacagt tagcaatcga ttttcataat
     2641 cagcttccag ccgatgaagt tccagaaaaa acggaaggat acgaaggttt cttccatttg
     2701 atggcattgg atgggaatcc tgaagaagct tctatgagtt atatcattcg cgatcatgat
     2761 cgtgaaaaat tcgaagcacg caaagcacaa atcacacata tccaagaaga gttgaatcag
     2821 cgatttgatc aagaacgaat caaagtagat atgtatgatc aatattacaa catgaaagaa
     2881 atcattgaaa aagatatgag catcgtggaa ttagcgaaac aagcaatgat cgagcttggt
     2941 atctctccag tgatcgaacc agttcgtgga ggaacagatg gttcaaaaat ctcttacatg
     3001 ggtattccga cgccaaatct atttgccgga ggagaaaata tgcacggacg attcgaattt
     3061 gtttctttac aagtaatgga aaaagcaaca gacgtgattg taaaaattgc agaattgaac
     3121 acaaagagtt aaaatcgaaa aagaacagct tatgacaagg cgttcgtccc aatgatggaa
     3181 tgtcatctgt ctaaggctaa agggcaggac aatggaattg gttgtcccgc cctctttttt
     3241 gaagagtaaa taggaggtaa agaatggaaa agctgctagt tttttataac aaaagttcag
     3301 ggaaagatga gggtgagaaa ttagcacgct ggtttcaaga ttatgtaaaa gaaaagcagc
     3361 cagaattata tgtagaacta gctgaaactg gcccatcgat tgatgatgcg gaattagtca
     3421 agaaagcaga agccatagaa gctgatactt tagtaattat aggtggagac ggcacgattc
     3481 atcatatcgt ccaagcgttc caaaaaacat tatctcaata ccatgtcgga ttacttccag
     3541 gtggaactgt caacaacctt gcacgtgttc ttgagattcc cctcaaaaaa gaagaagctg
     3601 ctgacgtgat cctggaaggc aatgtacgga aaatagacta tggtcaagtc aatgatgaag
     3661 tcattatctc tacactgaca atcggaatct tagcagatac agcagtttgg atcagtcaag
     3721 aagaaaaaca gcgttacggc tcgtggatct ttatcaagaa gttttttaag ttattgctga
     3781 agaagaaaaa atatcatttg gatttagaaa cagacgagga gcattggaaa ggaaaatccc
     3841 aactgttgac agtcacgatg tctaactccg tgggcggttt tacaaatttt gacgactcag
     3901 cgaccctaga tgatggaaaa tttcatgtaa cgatcgtacc ttccttagat attttccgat
     3961 ttatttttta tttgcctaga atcatgagag gcaaattcta tacgatcccc ggcattactt
     4021 atttcacagc caaacgcatg aaaatccaag cgcaggaaaa atctgtgggc actcgaacgg
     4081 atggagacac gacagatgat cttccagttg aattatctgt tgtatcaaaa ggattaacag
     4141 tttattcacc aaagaaagaa gaaaaagctt agaaatagta gttaacagaa agttggaaga
     4201 agagtaatgg atgtattgtt acacaatctt ttgtggtttt accttttcat tgtgaatttt
     4261 tacttatttt gtctgatggg gtatgataaa catcaggcta gaactagcgg ctggcgtgtt
     4321 cctgagaata atttgatatt tgtcagcctg ttaggcggtg gtttgggagg attgatctct
     4381 cgaaaagttt tccatcataa aactcggaaa aagaagttta ctataggatt cgctgcaggt
     4441 gtacttgttg atttgattct catttatttt ttccattaag gagcaggaga tgtcgtctaa
     4501 aggaacgaaa actaaaatca ttctgaatct gcttttgctg attgtgattt ttgccattat
     4561 ttattattta atcaatcaat catttgcaga tatctttgcc gaattgctgt ctaccagtgt
     4621 tgttgttttg gcagcggctg ttatattagg gacagtttac caaatcgctg aagggcgctc
     4681 aatcaaagaa attgctgaac ctttcgcgcc gaattttaca acgaaagatg ggttcttgac
     4741 ctctagctat attgcgtttt accgaatcgt ttcgtttggt acaggaacgc tgatctcgga
     4801 gatttatttt tataacaaaa aaggaatgaa gctatcccag ggagcagggg tgacagcact
     4861 ccatatgatt atgtacaaac tggcagtgat cacttatgca ttagctggct tggtcatcca
     4921 attctctctt ttttattcta atggtccatc aatgatctgg tttatcatcg ctggtatcct
     4981 tttgacgatc gtgattgttg cctttttatt ggcgatgtcc gtcagcttga atgttcaaat
     5041 attttttgtc agcttatcga ataagttatt taaaagtgag cgtttgcgga aatgggtgga
     5101 tacatgcaat cagcagatct actctttaag ggaaacggtc caaaccatta tccaagacag
     5161 gactgcgcta ttgcggattt atctatggaa tatgttaaaa cttgtatttt ggtatgtact
     5221 tccttatttg attctgattg aaaaccatcc taaaatagat tttctactga ccatttcgtt
     5281 tatcagcttt gcagtagtgc tttcaggggt tattcctacg cctgctggta ttggttcctt
     5341 tgaatttgtc tatttgttat tattcagacc agttgttgga acagttgacg cagtttcttc
     5401 gcttttactg tatcgtttca gttcctttat cttgccattt ctctatggat ttgtgtatgt
     5461 gattgctgaa cggcgaagag tgatcaaaga agaaataata gaagtaaaaa aagagaataa
     5521 agaaaatcaa gggtaggtct tttataagat ctaccctttt tatcaaatca aagaaaaacg
     5581 ttatggataa gataatttta cgtttgtttg gctctttttt tatatacata caatcaattt
     5641 tgttttttta agatttatat aagtcgagaa aaaaagtcaa aaaaccatgt gtatattttg
     5701 accaaaattg accaaagcga tataatagtt tttgtaaaga tcaaagaaat aagtgatctt
     5761 acctttaatt aggagggtat acctgtatga atattgagaa aatgactacg acgcttcaag
     5821 aagcgattgc tgaagctcaa cagattgcgg tcactcgaaa acatcaagat atcgacattg
     5881 cccatgtatg gaaaatcttt ttacaaccta atcattttgg tcgaaatttc tatacggatg
     5941 ccggattgga tgtcgaatct tttgaacatg aaattgatcg tctactggat gagtatccag
     6001 ttgtttctgg tggaaacgtc caatatggac aaaacctcag ccagaatttc tttcgattat
     6061 tgaatgaagc agaccaaata cgtgaaagct tcggcgacga gtttctttca acggaagtcg
     6121 ttattttagc gttgatgaaa ttaaaaaatt atccgttaac tgtttatttg aataaaaacg
     6181 gattatctga aaaagaattg cgtaaaaaca tcgaagagat gagaggagga gaaagagtga
     6241 cctcacaaaa ccaagaagaa caatacaaag cattagaaaa atacggcgtt gatttagtac
     6301 agcaagtcaa aagcggaaaa atggatccaa tcatcggtcg tgatgaagaa atccgtgatg
     6361 tcatccgtat tctttcacga aaaacaaaaa ataatcctgt tctgatagga gaacccggtg
     6421 tagggaaaac ggcaatcgtt gaagggcttg ctcaacgtat cgtacgcaaa gatgtgcctg
     6481 aaaatttaaa agataaaacg attttttcat tagatatggg tgcattgatc gctggagcaa
     6541 aattccgtgg tgaatttgaa gaaagactaa aagcagtctt gaaagaagtc aaaaaaagtg
     6601 atggacgtat cctcttgttc atcgatgaaa tccacaatat cgtaggggca ggaaaaacag
     6661 aaggaagtat ggatgccgga aatctgttga aaccaatgct tgctcgcggt gaattacatt
     6721 tgatcggtgc cacaacttta gatgagtacc gtcaatatat ggaaaaagac aaagcgttgg
     6781 aacgtcgctt tcaaaaggta ttagtcaaag aaccaacagt ggaagatacg atcagtattc
     6841 tgcgtggatt aaaagaacgt tttgagatcc accatggtgt taacatccat gacaacgcat
     6901 tagtagcagc agctacttta tctgaccgtt atattactga tcggttctta ccggacaaag
     6961 caatcgattt gatcgatgaa gccagtgcaa cgattcgggt agaaatgaac tctatgccaa
     7021 cggaattaga tcaagttact agacgtttga tgcagttgga aatcgaagaa gctgcactga
     7081 aaaaagaatc agatgatgca agtaaaaaac gcttgaaaaa tttgcaagaa gaattagctg
     7141 aacttcgtga agaagcaaat gcgatgaaga tgcagtggga aacagaaaaa gaagaagtca
     7201 attctgtttc agcaaaacgt gctgaaatcg ataaagcaaa acacgaatta gaagatgcag
     7261 aaaataacta tgatttagaa cgcgctgctg tattgcgtca tggtacgata cctcaattag
     7321 aaaaagaatt gaaggaatta gaagctaaag caaaagacag cgagattaag atggttcaag
     7381 agtccgttac cgaaaatgag attgctcaag tcgttggcag attaacgggt atccccgtaa
     7441 cgaaacttgt agaaggtgaa cgagaaaaac taattaaatt gaatgaaaca cttcataaac
     7501 gagtgattgg tcaagatgaa gcagttgatg cggtcagtga cgcggtaatt cgttcacggg
     7561 ctggattgca agacccaaat cgtcctctag gttctttcct tttcctagga ccaactggtg
     7621 tcggaaaaac cgaattagcg aaagcgttag ctgagaactt gtttgactca gaagatcata
     7681 tggtacggat cgatatgagt gaatatatgg aaaaacatgc tgtgtctcgt ctagtcggag
     7741 ctcctccagg ctatgtaggt tacgaagaag gtggtcaatt aacggaagct gtcagacgaa
     7801 atccttatac aatcgtcttg ttggatgaaa tcgaaaaagc gcatcccgat gtcttcaata
     7861 tcttgttaca agtcctagat gacggacgct tgactgattc aaaagggcga gtagtagatt
     7921 tcaaaaatac ggttctgatc atgaccagca atatcggttc acagttactg ctggaaggcg
     7981 tgactgctga tggaacgatt ccagaagcag tggctgaaca agtcaacacg ctattacgtg
     8041 gaaacttcaa accagaattc ttgaaccgaa tcgacgacac gattttattt acaccattga
     8101 gcctagacaa cgtgaaagga atcgttgaca aaatggtggc gcaattggca caacgtctgg
     8161 aacatcaaga aatcctgctg acaatcagtg atgaagccaa aacgtggatt gctgaaaatg
     8221 cttatgaacc agcatatggt gcaagaccat tgaaacgatt tatcactaag gaagtagaaa
     8281 caccactagc taaagaaatc gttgcaggac atgttatgcc taaatcaaaa gtaacgatta
     8341 ctttacttga tggacaactt catttcaaaa cagaagagct agaagaaatc gtctaatctt
     8401 ccattgagac tataaaagaa aaaaggggtc tgacacaact agtgtcagac ctcctttttt
     8461 caaataaaca gtgttccaga agtagtttct tcgaaaaata agccgaaatt tcttgaagct
     8521 gcccgcttct gtcacaacct cttttattag gtatttttca ctttttctaa tttataactt
     8581 tcaaagtaac gctcatcttt tttactttga gaccatgcaa acaatcccat taaggcagca
     8641 cctatcgtat ttgtcagcaa gtcgcccatc gtatccatca atgctgctcg tccgacaaac
     8701 agtgtgccat cagaagcagc aaaacgttga agattcatgc ctaagaactg gtcgcataag
     8761 aattcccaga actcccaaaa cacgccgcaa agtccagcaa acgcaaagcc gaataagagg
     8821 aacaaccaag gactggtttt tgatatctca gcatctttca tcaagtaacc aatcaatcca
     8881 tagccaagag ctgtcaggac cattggactc accgcatgta agattttgtc ccaaaaagag
     8941 atgatactga tcaaatgcat ccctgtgcct aaaaagacag agatgaacaa gaaaaaccag
     9001 taaaacaaaa cgattgctgc tggtatttta agtttgaaaa ctttcaaaat gacttgtggc
     9061 atgaaaatca atgcaatccc taataaagat tccacgataa atgtgattcc ttgagaagtc
     9121 gaatattttt gtgtgataaa ttcataaaaa ttatagcaga caacgaatac accaaaagca
     9181 agtaaagcta tttgcacctt tttgatttct ttaatcactg aaagtccctc catctaaaaa
     9241 tctttttact tctgaaagca actcaatttc tgaagaaacc acttttccgt tcaatttgat
     9301 caaacctatt gtatataagt tcaggtagtg aaattgattt tcagctgttt cttgtagtgc
     9361 agcgattttt ttcgggtggg ttccgccttg ctgtcgagta tcagtatata agccgatcac
     9421 tgggatgcct ttcgcataag ccacaccgat ttccgatgct accccggcat cgatcgtcag
     9481 cccatctagt aaagcaatca ttaaatcact agccaacact ttttctgtgt cagcaagagc
     9541 aatcattcga ctgtctgcat aagcagtttt gtcattgatt gcttcatttt cttgaggaag
     9601 atagatcgaa agctcagaag agagctctct gatttcttta actaactgtt ggttatataa
     9661 caaatcactt ttagcaaaca ttggtgcggc aaaataaatt ttcatctaaa catcatcctt
     9721 tttatcaaaa ataatcgcta aagtaagctt ccatgtttgg aatgatacgc tctagtgact
     9781 tcagtgtttc ttcatctgtt tctaaccgtt cgattcttgc caaataagaa gcacggcgat
     9841 aattcatcat caagcaagtc aatgtttgga tatccagtcg aacggatttt cctataggtt
     9901 catttaagac acggacttgt ccctgttcat cccatgttaa agcgaagaca ccattattcc
     9961 aaggagcgac aggatcttca atgatgaaat gaaaagcatc agctgttcca acaaacggaa
    10021 accgttgaag gaattctttt acatcaacga tccgagccat aaaatatggt tcgatctgct
    10081 ctttgatctg actatcttca atcaaaaatg ctaaaggctc atttttataa atatctccat
    10141 gtacccagta gatcatggaa aaatgtgcgg aaataaagtt ccataagcca tttcgagctt
    10201 cttgatcaag atagaacatt tcttttacgt gaaatatttc ttcagctacc cagtagaaca
    10261 gaacacctct tggttcatgg ttgctatcgt agtagacagc ggctgtgcgc tcatcttcat
    10321 tttcgaaacg ccaatactct tcccaatgaa aatcactgcg gaataaagca ccatggtttt
    10381 gttgggcaaa tttgtcataa acggaaaata cgtctggatg atcaactggt aatcgctcaa
    10441 ccataccact tactgggatt tgtttaggta gctgtgtatc tctgatttta aaggaaagtt
    10501 tatcagacat gatttcccat cctttacgcc gatagtaggg gatactgtaa ggatacaaat
    10561 aagagatcca ttgcttattc ttgcgcatat tatccaatgc aacgataatt agatcttgca
    10621 tcaatccatg gttagcatat tctggataag ttccaactcc agtcacacca cccattttat
    10681 aacgtgcacc gtgaatattg acttcacaag gatagatagc gatttgagag atcagtttat
    10741 tttcgtggaa ccatccgaac actttcgata cttccaaaat cggttttttg gaacggataa
    10801 aagctcgttt attctcaaac ccgctttcct cgatgtctgc ttcagtcact tggaacacat
    10861 aggaaagcaa ttcattgaat tgatcgatat gttcttgagt gaccggtttt aattcaagat
    10921 tttctctaaa atctttttga tccatttttt catctccatt tattagcttg ataacagtat
    10981 agcaaaattc tacaaaaaaa acttctatag ctgactaatt aaaaactctt taaattactg
    11041 cttttcgttg gtataatgga aagtgctgat tatatgaaaa gaggagacgc tatggatata
    11101 aagaaaatga aagaacgcca agagcagatt cgtaattttt cgatcatcgc tcatatcgac
    11161 catgggaaat ctacattggc cgatcgtatt ttagaaatga cgcacactgt gacgtctcgc
    11221 gaaatgcaag atcagctgtt agactcgatg gatttggaac gtgaacgtgg aatcacgatt
    11281 aaattaaatg ctgtagaact caattacaca gcgaaaaatg gagaaacata tatctttcac
    11341 ttgattgaca ccccagggca cgtcgacttc acctatgaag tctctcgaag ccttgctgcc
    11401 tgtgagggtg ccgttttagt ggtcgatgca gcacaaggaa tcgaagcaca aacattggcc
    11461 aatgtttatt tagcgttaga caatgatttg gagatcctgc cagtcatcaa taaaatcgac
    11521 ctacccgcag cagatcccga acgtgtccgt caagaaatcg aagacgtaat cggaatcgat
    11581 gctagtgaag ctgtattagc cagtgccaaa tcagggattg ggattgaaga tattctcgag
    11641 cagatcgtgg aatatgttcc tgcaccaagt ggagacttag atgcaccgct aaaagctttg
    11701 atctttgact ctatttatga tagttaccgc ggtgttgttc taaatgtccg gatcacggac
    11761 ggtatggtca aacccggaga caaaatcaaa ctgatgagta atggcaaaac atttgatgtt
    11821 acagaggtcg gggtcttctc gccaaaagca gttgctagag actttttgat ggtcggtgat
    11881 gtcggttata tcacagcaag tatcaaaact gtccaagata cacgagtagg ggatacagta
    11941 acgttagcag acaatcctgc cgctgaagct ttaccaggtt accgaaaaat gaatccgatg
    12001 gtttattgtg gtctttatcc aattgatact tctcgttaca acgatttgcg ggaagcttta
    12061 gaaaaactgc aattgaatga tgctgcttta caattcgaac cagaaacctc tcaagcatta
    12121 ggttttgggt tccgctgtgg attcctcgga cttcttcata tggatgtcgt ccaagaacgc
    12181 ttggaacggg aattcaatct agaattgatc acgactgcac catccgttat ttaccatgtt
    12241 aataaaacgg atggtacgac tgctacagta gataacccgg cagattttcc tgaacctgta
    12301 acgattcagg atgtagaaga accattcgtc aaagcacaga tcatggtccc aaatgatttt
    12361 gtcggtgcag taatggaact ttctcaacga aaacggggag aattcattac gatggattat
    12421 ttagatgatt accgagtaaa tgtcgtctat aatattccgc tttctgaaat tgtctttgac
    12481 tttttcgaca aattgaaatc aagcacgaaa ggctatgcct cattggatta tgaaatgtct
    12541 ggttatcaaa aaagcaagtt agtgaagatg gacatcttgc tgaatggaga aaaagtcgat
    12601 gcattaagct ttatcgttca ccgagacttt gcctatgaac gtggaaaagc aatcgttgaa
    12661 aaactgaaaa aactaatccc acgccaacaa tttgaggtgc caatccaagc agctattgga
    12721 caaaaaatcg ttgcccgttc agacatcaaa gccttgcgta aaaacgtctt ggctaaatgt
    12781 tatggtggag atgtttctcg taaacgtaaa ctcttagaga aacaaaaaga agggaagaag
    12841 cggatgaaac aaatcggctc cgtcgaagtt ccgcaagaag ccttcatggc cgttctgaaa
    12901 atggacgagg acgaaccgaa gaaatagcaa gggtttgttt gaaaacagt
//
LOCUS       DAFBSV010000080        12670 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.081, whole genome shotgun sequence.
ACCESSION   DAFBSV010000080 DAFBSV010000000
VERSION     DAFBSV010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.081"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            6..305
                     /locus_tag="LLB18_002201"
     CDS             6..305
                     /locus_tag="LLB18_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5245186.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="LLB18_002202"
     CDS             378..1739
                     /locus_tag="LLB18_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBK5245187.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="LLB18_002203"
     CDS             1761..2021
                     /locus_tag="LLB18_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245188.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="LLB18_002204"
     CDS             2035..2787
                     /locus_tag="LLB18_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBK5245189.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="LLB18_002205"
     CDS             complement(2881..3486)
                     /locus_tag="LLB18_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK5245190.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="LLB18_002206"
     CDS             complement(3539..4513)
                     /locus_tag="LLB18_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HBK5245191.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="LLB18_002207"
     CDS             complement(4891..5610)
                     /locus_tag="LLB18_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK5245192.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="LLB18_002208"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="LLB18_002208"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBK5245193.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="LLB18_002209"
     CDS             7161..8558
                     /locus_tag="LLB18_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBK5245194.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="LLB18_002210"
     CDS             8639..9079
                     /locus_tag="LLB18_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBK5245195.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="LLB18_002211"
     CDS             9227..9553
                     /locus_tag="LLB18_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBK5245196.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="LLB18_002212"
     CDS             9554..10303
                     /locus_tag="LLB18_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245197.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="LLB18_002213"
     CDS             complement(10383..10838)
                     /locus_tag="LLB18_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBK5245198.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="LLB18_002214"
     CDS             complement(11265..11540)
                     /locus_tag="LLB18_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245199.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="LLB18_002215"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="LLB18_002215"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBK5245200.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
BASE COUNT         4055 a         2175 c         2587 g         3853 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaaa
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag
//
LOCUS       DAFBSV010000081        12597 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.082, whole genome shotgun sequence.
ACCESSION   DAFBSV010000081 DAFBSV010000000
VERSION     DAFBSV010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12597
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.082"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(10..159)
                     /locus_tag="LLB18_002216"
     CDS             complement(10..159)
                     /locus_tag="LLB18_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245201.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            555..755
                     /locus_tag="LLB18_002217"
     CDS             555..755
                     /locus_tag="LLB18_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBK5245202.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            1323..1886
                     /locus_tag="LLB18_002218"
     CDS             1323..1886
                     /locus_tag="LLB18_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245203.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(1947..2291)
                     /locus_tag="LLB18_002219"
     CDS             complement(1947..2291)
                     /locus_tag="LLB18_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245204.1"
                     /translation="MISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFHYSPYRLF
                     QYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHDEVYLAEC
                     LANLEQKGIYLT"
     gene            complement(2388..2633)
                     /locus_tag="LLB18_002220"
     CDS             complement(2388..2633)
                     /locus_tag="LLB18_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5245205.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(2703..2957)
                     /locus_tag="LLB18_002221"
     CDS             complement(2703..2957)
                     /locus_tag="LLB18_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245206.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(3121..3444)
                     /locus_tag="LLB18_002222"
     CDS             complement(3121..3444)
                     /locus_tag="LLB18_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245207.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            3631..3704
                     /locus_tag="LLB18_002223"
     tRNA            3631..3704
                     /locus_tag="LLB18_002223"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3665..3667,aa:Ile,seq:cat)
     gene            complement(4089..4586)
                     /locus_tag="LLB18_002224"
     CDS             complement(4089..4586)
                     /locus_tag="LLB18_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBK5245208.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(4626..5435)
                     /locus_tag="LLB18_002225"
     CDS             complement(4626..5435)
                     /locus_tag="LLB18_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBK5245209.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIDMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            5769..6626
                     /locus_tag="LLB18_002226"
     CDS             5769..6626
                     /locus_tag="LLB18_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBK5245210.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            6619..7521
                     /locus_tag="LLB18_002227"
     CDS             6619..7521
                     /locus_tag="LLB18_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBK5245211.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVSDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            7554..7904
                     /locus_tag="LLB18_002228"
     CDS             7554..7904
                     /locus_tag="LLB18_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBK5245212.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            7953..8876
                     /locus_tag="LLB18_002229"
     CDS             7953..8876
                     /locus_tag="LLB18_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBK5245213.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            8954..9847
                     /locus_tag="LLB18_002230"
     CDS             8954..9847
                     /locus_tag="LLB18_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBK5245214.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            9885..10448
                     /gene="amaP"
                     /locus_tag="LLB18_002231"
     CDS             9885..10448
                     /gene="amaP"
                     /locus_tag="LLB18_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBK5245215.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            10462..10650
                     /locus_tag="LLB18_002232"
     CDS             10462..10650
                     /locus_tag="LLB18_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBK5245216.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            10663..11565
                     /locus_tag="LLB18_002233"
     CDS             10663..11565
                     /locus_tag="LLB18_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBK5245217.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            11597..11839
                     /locus_tag="LLB18_002234"
     CDS             11597..11839
                     /locus_tag="LLB18_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBK5245218.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(12095..12466)
                     /locus_tag="LLB18_002235"
     CDS             complement(12095..12466)
                     /locus_tag="LLB18_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245219.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         4461 a         2113 c         2367 g         3656 t
ORIGIN      
        1 ttccactcct tatgcagatt tttttaattc ttgcactgct tgttcgatcg taacacctgt
       61 cgctacatga ttggtatttt ctttgtcaaa aacgacaaat agattcaaat ctgtatccaa
      121 ggttactcga tattgtatat ctttgttata gaatgtcata gccattctcc tttctttaaa
      181 tacttgctga aaggcaacga acgcgttgat aacgaaattc catttataag tataccacca
      241 attgaaaggt tttcatagtt aagaaatttt aaagtcaaaa gttgcagata aaagcaaata
      301 aacaagaaaa caaaaagtga atcaatcgcg gttattcaac tttttcttcg attcgaagac
      361 aatagaagac aatgaatttt atatttcatt gcattatcct tgtgttatta gaaaaagcat
      421 gatatattaa atgagtaatc tattttgaaa cgtaatttga gcgatatatc tacatagata
      481 aaactccttt tgcctatcaa atatttattg caacgaaaaa acgtacattg atacgtatca
      541 ggaggaattt atttatgaat aacggtacag taaaatggtt caacgcagac aaaggttttg
      601 gctttatcac tggtgaagat ggaaatgatg tatttgcaca tttttcagct atccaaggtg
      661 acggcttcaa aactttagaa gaaggccaag cagtgtctta cgatgttgaa gatggtcaac
      721 gtggccctca agcaacaaac attgttaaag cttaataaaa attgactttt aaccgtcttt
      781 tcgaaagaaa agacggtttt tttgtacgaa aaaattcatt ggtcgttgaa tgggctgaat
      841 agtagtgtat aaaacaattt tgtggagcgt gaagctttta tggtagagga aaatacgaat
      901 aaagtgatgt tgataaaaag attcctatct tgaatatgaa tcgagatgtc ttgaaaatga
      961 atgagtttga ccaatcatta tcctatcgaa atttacagtt tcgttcgatt ggtctgtcaa
     1021 ttaatgaaaa agtaaaaaag aatatgttct aggaagaggg cggcacatct aaatttttaa
     1081 gtaacggaca gttcaaatat caagcattga aagaggctat cctactgttt gaaggaatac
     1141 gaatatataa aaacgacaaa gaggaaaaag tagttcatta aatcccttca agtgatgaaa
     1201 gaatgagatc taataaaacc tgatctttca tctgtttttt taataacgta ataatttttt
     1261 tattttttgt gctttcgccg ttattgtaga gtgatttagc attcttattt ttaaaaataa
     1321 ctgtgttata tattaaaaaa ggcataatag ttataagctt ttttaaagaa tatttagaaa
     1381 ttattaattt tcgtctgaaa acaaaaaaag aaagcgttat tattttagtc tattttcagg
     1441 gggggaacct tatgataaaa aaactatttt tactatcaat attaacgcta gcaatggcag
     1501 gttgttctga ctctggctta gcaactgaac tgatcacaaa atcaactgaa gccacgacag
     1561 aggagttaaa atgtggaaac gatcacagtg actacagagg cttaaatcga cgatgcatgg
     1621 gaatattagg cagaagcaat tgtaagcatc gatgtagtaa tcgaagaagg tgtagaagaa
     1681 gcaacagaaa aatcaaaaga aagatcaaaa gaagcaatct gtgctgtgca tcgtatacag
     1741 acgtcgaaga tgcggtactt ttaaaccacg tcaggagatg ttcatttatg tctagggaag
     1801 ttggcgatga accaaaacta gagtacgctt ttagttttgc acgtgaggat gaagataacc
     1861 ctaaaactta cgacatttta gcttgatcta agatggttaa agctttttaa tgaagtaaga
     1921 ggagatagaa ggcttttcta gttatattag gtaagataaa ttcctttttg ctccaaattt
     1981 gctaaacatt ctgctagata aacttcatcg tgttccggat aaatcggcac gttgcgctct
     2041 acagtaggta aatcaaaaaa tgcttcgcat gatttgccac gatacatagg atttttccac
     2101 tctggtgctg ggctgtaacc acgtttttcc atttcatcca tgacaagctg atgatattgg
     2161 aataatctat aaggagaata gtgaaaaaca taatccacag tagcatgttt ctttccccag
     2221 ccatttcctc ttaatgcaca gcattcccga tgttgtccta aaagctgttg acgaggaagc
     2281 tttgaaatca atttttcatg ccataatcac atagaaatgt ctcctttata tatagattgt
     2341 taaccttaga cgttaaatga aaaaaccagc accaaggctg gaaaaaatca cttcagtttg
     2401 cttgctgttt ctgagcgacc aattaggtaa tcaacggaaa tatcgtaaaa gtcagcgata
     2461 tagattaatt caatgatgct tggaatttct tctccttctt cgtacttacg atatttgaat
     2521 aaaggaatac ttaacgcgct agaaacagct acttgagata aagatcggcc agttcttaag
     2581 aaattcagac gacaacgtaa agtatccagt aaaatagctt cttcgatact catttaatca
     2641 cctttcatta tagtagaata gttataatga ctatagaaag ctacacatgc aatcaatagt
     2701 actcaatgtt ttttatttaa acgtatcaaa taaagaatga cgatcaataa agacaaaacc
     2761 agtcctgata attcttctat aaaaacacta tcgggttcaa agtagttgta attaaaaact
     2821 ttccacataa agtagatagc cggaagagtc aaaatagcta aataaaaccg ttctttgttc
     2881 caattcataa gataaacaat acttgcgacc agtgcgaccg caggcaccca aaacaaaact
     2941 ctcaccaacg taatcatgta acggactcct caacgattca tataataaaa gataacatgt
     3001 tattgcatac atcacaaatg aaatgctagg aaaataaaag aagaatagat caatgaaaaa
     3061 tgaaaaagca gaacagtttt ctgctgataa gcaggaactg ttccgctgaa tgtgtcttat
     3121 ctatcgagaa aaaatcaatg gattgatatc taagtaattc aatacatata aaaagaggac
     3181 gatcgcattc actaaaaagg aaagaatgat gatcccatag cgaatggaaa catatttaac
     3241 aaatactttt gtttgaatac gggcatatct ttttccttta tagctgagca tcatgacaag
     3301 aagcaaaagg gtaatcacac cttgaaaaat cattccaata aacagaattc ctgaggtttg
     3361 ataatttaat tggagaaaat aagctgctgc cgcaactaaa tcgaataaaa tcgcaataaa
     3421 tggcaaaata atcactccta acattgagaa taaataaaag aataacattt tttctaaaat
     3481 aagcaaataa aaattaaagt aacaaaatag ttatgacaca agtaaaagaa ataagaataa
     3541 caatattatt ttacttatat tttgaaactt gtgagagttt gtcattcgtg ctatagttga
     3601 aaagtaacaa aaataaattt tatttatgat gtacctttag ctcagttggt tagagcagac
     3661 ggctcataac cgtccggtcg taggttcgag tcctacaagg tacataagag gttgtgaaaa
     3721 agctgccctg catcaagtaa taagaacagc caagtaaaaa cagcttctta tgtttttact
     3781 tggctgttct tattactgca gatgcaagct tttgaatacc gtttaaggaa gaggttgtga
     3841 aatcagcgtt ttgacctgag tattagctta acaaacggaa aaatagttcc tcatattttg
     3901 ccgtttgtta agctaatacc gagggtcagc tgattgaaca ccatttaaga aagaggtcgt
     3961 gagcctgccg tttcactctg tgtcataaaa aagccaatct actttgatag aaaaagcacg
     4021 taggactaaa acagttctgc gtgctttttt tattgtgtgt taaatatcgt aaatgaagat
     4081 agatattttt atgattcgac gatagagacg ttgaaatctt tcaacagctc taaagcggat
     4141 tctccgtgtt ttctactgga gactaacatt ggatcaacaa aaaagtctgc ttcaggaaaa
     4201 gcactctgca ggcctatcag attagagagt acacacaagt ttgtttcaat cccgactact
     4261 tcgatctctt tttgttcttc tttgctttca aataaagttt cctggatttc agctaaagtt
     4321 tcaggtggaa tcgtaaagta atacttttta atcactcgtt cattttcttg tggagaaaga
     4381 agagggatca attgcaaatc ttctcgttct tcttctttgt ccttcagttc aactggtata
     4441 tcccgtgtga agagaatata ttcattattt tggcgtgctt tagctaatct ttgagcaata
     4501 cgttctgcca attgatctga ctctggaata taaaattcgc tgtttggatc aagaatatga
     4561 ttttgcatat caataataac taacattttc tttcctccta cattcatatc gtcattttat
     4621 tctttttaat agaagttttt taaaatataa gcaacaccag cttcttcatt cgtcagtgtt
     4681 acttggtttg caatttcttt tacttgtcgc tgtgcattcc ccatcgcaat actcaacccg
     4741 ctgtaattca acatatcaat gtcgttttct tgatcgccaa aagccatgat gtcactcgat
     4801 tcgattccaa ggtaatccgc cagaaaaaca agtgaatgag ctttagtgat acctgtaggc
     4861 gtgatttcta agaaatgcgg atcagagaat actgattgga taccatctgc ttgcagatct
     4921 ctttgtagct tctgtagttt ttcttcactc ttatctgtta atgctaattt aagatagcta
     4981 agagaaggat cttccaacat atttaaaatt tgatcaaaag aatggttctg taaattgaaa
     5041 tgttcataat aagggtcatc tttgactaga tttgattcat cgaatgtcag ctgatcatct
     5101 tgggtttctc ggctagcaat gatggatatt ttcgcttctt gagcatagaa gaaggctttt
     5161 ctcagtgtat cgctatctat ttttgaacgt ctgagaactt tcgccatttt tccatccttc
     5221 atttcagcaa tcagtgaacc attggaagaa atcaaatagc caccgattcc taattcggaa
     5281 aaaatatctt tagcagaaat gctgttcctt ccggtagcga cggttacgat tccgccattt
     5341 tcatcaaatt tccgaagtgc ttggatattt tcttctggta tctttccatt tcgatcaagc
     5401 aaggtaccgt ctaaatcaat cgctgctagt ttcattttat cttcctactt tctttttaca
     5461 tatctatttt cctgttacct taagattaaa tgagaattta aaaaaatgaa actaacttgc
     5521 tttgtcatta tgaatttttt caaaaaacat tcttaagaaa aaggtggcta tatatagtag
     5581 tttttggtca atacctttga ataaaaagcc atgaaaaacg aatagttagc gcttaccgat
     5641 gcgttttgtg ataaaaaaat tttaaaatat tcaatgaaaa caaagcatat attttgcttt
     5701 aaaaccaaat gaggaatatt ctagatgtag aacaggttag aaaaagatta gaaaaaggag
     5761 tgattttgat ggagaagaga tacggcgtag ttcctgtggt aactgcttca gacgaaaatt
     5821 atgctcctta cttgagcgtg atgatcgcaa ctgcattaga aaattgcaat aaaacaagac
     5881 gcataaaatt ttatgtgatt gacgatggtc tatcagaata tagtaaagaa ggattggaag
     5941 aaacggtaaa taaatattca agtaatgcaa gtatccaatt cctgacagtg gaaaaagata
     6001 tctacgaaga cttcctagtc agtgaccata tcacaactac cgcttactta agaatttctt
     6061 taccaaactt attagctaaa gaggattata agaaagtcct ttacttagat tcagatgtgt
     6121 tagtactaga cgatatcgta aaactatatg atgagccgtt aaatggaaaa acaatcggcg
     6181 ctattatcga tccaggccaa gtgaaagctt tggaaagatt aggaatcgat tccgatgact
     6241 tgtacttcaa ttcaggagtg atggtgattg acattgatca atggaataaa aaagaaatta
     6301 cagaaaaaac tatccattac ctcagtgaaa atggcgatcg aatcatctat cacgaccaag
     6361 atgctttgaa tgctgtactt tatgaagatt gggaacaact tcatccaaaa tggaacatgc
     6421 agacttcgct gatttttgaa cgtcatccag caccaaatga aaaatatgaa cgtcagtata
     6481 aagaaggaaa tgaaaaacct tcgatcgttc actttacagg acatgataaa ccttggaata
     6541 cgttgaaaga tcatccgtat accaatttat acttaaaaaa attagcacac agtactctaa
     6601 cgaaagtagg cgagatcaat gaataaaaaa gaaatagcag tagtcgcaag ttgtaacaca
     6661 aaattcgtac cacatttagc tgcattattt gtctcagtat tagataattg caacccgtct
     6721 aaatttgttc ggttctatgt gagtgacgat gatatcgatt ttgaaagtaa acagctttta
     6781 cgcttctcag tgaaaaacgc acgaatgaac tcagatgtgg aattcttgaa aatcaataaa
     6841 gaattcttta caaatgtggt aatcagcgat cgtattccag aaacagctta ttatcgtatt
     6901 gcgattccgg aattgttccg cggcacagaa gttgaacgta tcttatatat ggattgcgac
     6961 atgatcgctt tacaagatat ctctaaatta tggcgtcttg acttcggtga ttcaatcgta
     7021 gcagctgttg aagacgctgg gttccatcaa cgactggaaa aaatgaaaat ttcagctaaa
     7081 tcaatgcgtt atttcaactc aggtttgatg ctgatcaatg tgaaaaaatg gttagatgaa
     7141 aatattacgc aaaaagtatt agatttcatc gaacataatc cagaaaaatt acgattccat
     7201 gaccaagatg cattaaatgc tatcttacat gaccgttggt taccacttca tccgcgttgg
     7261 aatgcacaag gctatatcat ggcaaaagca aaaaaacatc caacagcagc aggtgaacgt
     7321 gaatacgaag aaactcgcaa caatccttac attatccatt tttcaggaca tgtgaaaccg
     7381 tggagcaagg attttgaagg gccaacgaag aaatattacg aaaaatatgc agggatgacg
     7441 gctttccgtt gtgtagctaa attccctaaa tatccaaaat atgcaaaagt tcaaccaaaa
     7501 acagatgtag ttgttaaata atagaagaca acaactgaag agggggagta ggaatggaaa
     7561 ttacaatgtc taaaaatgca gtagagacgt taattgaaaa ggttggggaa aatacaaaaa
     7621 tcgcactcgc gcttatcaat gattccgatc catttctaag ggacaaaggt gcttttgcaa
     7681 aaggcagctt ttttcaaatc attccttttg tttcggaatt tggagaatat gcgactaaaa
     7741 tcgagcatcc attattggac atctatacat ctaaattaga gcaaaattat ttcggtaaac
     7801 gattgaacat ggacttcaac aaacagcttg acagcttttc attagaaaat gaaatcgcag
     7861 tactcgatta taatatcaaa ttaaagaact gcttcttcag ctaatagttt cgagaaagtc
     7921 caaaaaggag gtatacattg agatactact ttgtggatga agaaaagaat gtaatagaaa
     7981 cagatgaaaa aaaatataat tggctcgtac ttgatagtgc aaagcccgaa gagattgagc
     8041 aagcaatcga agaattcgag cttcctgatg atattttcgt aggaaccgaa tatccggaag
     8101 aagtttctcg gatggagcgc ctttatgaga cgaaactaga gcatccattt tctttggtag
     8161 tgattaatct agatcagtca gataatcgta tcgaaaaaaa attaacgcca atatcttttg
     8221 tactttccga taatctcttg attacttgta tcgatagaaa aaccgaattt gtggatcggc
     8281 tgctgacaaa gcatggaaat catttaaact cgtttgaaaa gatcatcacg tatacattat
     8341 tagatattta cacccattac gtgaaagaac taagagagat gaaaaagcga attgacgctt
     8401 tggataaagc agctcgtaaa acaacggaaa atgaagaact gtataaacag gcagatcttg
     8461 aaagagacat cgtatatatc gatcatacct taagagatca acgggaaaca atggatcaat
     8521 tatggaattc tgaaactttc atcaaacgtt tagacgatga acagctactc tatgatgtcc
     8581 atttgagaca gcgacaaaca gaaaaaatga tcgagatcta tcgagattta ttagagagta
     8641 ttggtgatct attcaacggg atgatggaca ataatctaaa tcatatcatg aaatatctag
     8701 attcagctgc attaatcatt tccgttccgg cgttgttcgc agggatttgg ggaatgaata
     8761 caggaggatt accgggtaaa agttctgctc taggctttat actcgtagtc tttggctctt
     8821 tgatagcagc agtagtttta ggttaccatt tataccggaa agattataca aattaaagaa
     8881 tctatttaaa acaggtatca aacaaagaaa tttgttttgg caatacaatt taaaaactag
     8941 gaggaataca gcaatgacag aaccaaaatt aatcgacccg cgaaacttgt accatacgga
     9001 gaaatttcct aaacaagatc aggatacacc agctttacag cagaatatga ttcctgttcc
     9061 tgattgtgga gaagaatcct atgaaggcaa taatcaacta gaaaaccgcc gtgtactaat
     9121 cactggtgga gattcaggga tcggtcgtgc agcagcgatt gcatttgcta gagaaggggc
     9181 agatatcgct cttcaattct tcccaggaga agaaaaagat gcagaggaag tagcaaaata
     9241 cgtgaaagtt gcaggacgta agattgtctt actacctttt gatcttcgtg acgaacaagc
     9301 acctaaagaa atcatagata aagccgtgag tgaacttggc gggctagata cgatggtact
     9361 aaacgcagga cagcaaattt cttgtcagtc tattgctgag ttaccacttg agcaagtcaa
     9421 agacacattt atgataaaca tcatcgctat gtttgcttta gtgaaagaag ctgttccgca
     9481 tatcccagca ggaggagcaa tcgtaacaac aacttctgtt caagcattca atccaagcga
     9541 acatttatta gattacgcag caacaaaagc ttcaatcgct aactttacga tcggtttagc
     9601 aaaacagctt gcacctaaag gaatccgtgt aaatggtgta gcacctggtc caatctggac
     9661 accattacaa ctagacgaag gacaaccttc tgattcgatc cctgaatttg gtcagcaaag
     9721 tttactagaa cgtgcaggtc agccaggaga attagcacca gtttatgttt tcttagcatc
     9781 gaataaagca agttatgtta cagcccaaat ttacggagta actggtggag aagcgatcaa
     9841 cttataagaa gttgatcgtt tcacccctat gaggaggtgc gaaaatgaat aaaggtgtaa
     9901 aaacgatcgg agtgatcgga acattacttt tgctatctgt gcttttgttt gcgatactat
     9961 taagtgcaac ctatccattg ccttttcagc tagagaagtt tcgattcttt tccatcacta
    10021 attcatacgt gcaacaatat gtattttggc ttgccgttgc atttgctatt ttgacaatta
    10081 tcacgttact tgttttcctg ttttatccaa aaacaatcgg aaactttcta ctgaaacatg
    10141 gtgatgggga gttgacgttg gataaaaaag caattgaagg aatggttcgt tctcacttgc
    10201 atgaagatga attcatccat tcaccaaaag taaatgtcaa agcaacgaaa aacaagatcg
    10261 ccgtcaatgt aaaaggggag ttgaaacgaa cttcagcact cattggtaaa acaggaacat
    10321 tgatgaaaga aatcgaaaat gaagtacaac acatattggg aacaaaagag ccagtgaaag
    10381 tatcggtgaa atacacaggc tttgaagaac cagctaaacg aagcaatgac cgcaaacgag
    10441 tagaataggg ggggaccaaa aatgaaagaa ctattttcga catacaagct ccctatcatc
    10501 tttggggtac ttggattgat attagccgtt ttatggatca ccgtgggctt tttcaagacc
    10561 ttattgatct tgatcatggc agcgatcggc gtcgctatcg gtttttatct gaaacaaacg
    10621 aaaatcttag atcactattt taaatcttag gaggaaacat ccatgaataa caataacaaa
    10681 aataataaca ataaaatgaa caaccaaaaa ccagtgtctg cacatccaga cccaacgaca
    10741 ccaaaccaat caaatggtgt gaacgatgaa aagaacaaaa cagcaccagt atctgcacat
    10801 ccagatccag tagtccctaa cgttcaacaa ggagtagaag agaagaaaca tgatgcagaa
    10861 aagcatgcac ctcatcatcc aggaactcca gaatctaaag ttccagaaca acatgatgca
    10921 atcgatcctt ctaaacctgt ggaagagcaa aaacatcctt ctgaccatgc gaaagcacaa
    10981 gaaaaactta gttctgacca cacaaacgga caaggaaaac ttggttctga tcatacaaat
    11041 aaccaaggaa agcatgattc tgaacaggaa gattcaatgc gcggtgagct gaattatgaa
    11101 gataaagttg tgcaaaaaat catcggaatc gcaattgaac aagtagacgg tttattatct
    11161 gcaaacggtg gtttcttctc taatgtggca ggaaaacttg tgaatacaga taatgtaacg
    11221 gctgggatcg aaacagaagt cggtaaaaaa caagtagcag ttgatatgga tgtcattgtg
    11281 gaatatggca aagatatcga aaaaatcttt gaagaaatgc aagaagtaat cggcaaagaa
    11341 gtaaaaaata tgacacattt agaagtgatc gaagtcaacg ctaacgtagt ggacatcaaa
    11401 acaaaagaag aatttgaaaa agatcaagaa acggtgcaag acaaagtaac tgacgcagcg
    11461 aaaaaaaccg gtgaatttgc ttcgaatcaa acagataaag taaaatcagc agctggaagc
    11521 ggcgcacaaa aagtaaaaga aaatacagaa ccacgggttc agtaataagg aagtaaaaca
    11581 ttaggaggaa cgaaacatgg gatttatttg gtcacttatc gtcggaggaa ttatcggagc
    11641 aattgcagga gcaatcacga ataaaggttc ttcgatgggg attattgcaa atgtcgtagc
    11701 aggtttagtt ggatcagcac ttggtcaagc attattaggt tcttggggac caagtattgc
    11761 aggaatggca atcgtgccat cattgattgg tgccatcatt ttagtactaa tcgtatcatt
    11821 ctttgctcga aaactgtaaa aagactttta aaaagaggtc gtgaaaaagc tgttcttcat
    11881 caagtaataa gaacagccaa acaaaaatag cttctcatat ttttcatttg gttgggcata
    11941 ttatcgaaga tgcaagcttt tgaacactgt ttatacggaa taagaggctg tgacaagact
    12001 tttgtcacag cctcttattt atgcgggcaa attcccaatt agatttttaa aagtttttcc
    12061 ttaaatgtgt ctttattgat acagagaagc ttctttaata aaacaatgcc tccctaaatt
    12121 ttcttgagat aggaaaggtg aacatacaaa ataatacgac cactttgaaa acccagatga
    12181 tccacaaatg gatcgtatga tactgatgaa gtaaaaagca atggatcaga aactcaaaga
    12241 gattgaaaaa gacaaggaag aaataatatc tcttttttac tcttgtctgt tttagccaat
    12301 aatagctcgt aaagtaatct agacaaacaa atagaagtaa acaaagtttc gtaagagcag
    12361 caatcgtatc atgttgctct gctagacgat tgacgagcag gaaaaatgtt ggtaatggaa
    12421 tatagatcac gagtaatgaa agaaaaaagt aaacaataaa tggcatacta ttcctcctaa
    12481 ttgtgtgagt tcgccctcat tttaaaataa cgatatttgt ttgtgaagct ttttcgtgtc
    12541 gtaacaaatg ttatctaatg tatttttaaa taaataatca ttattatcaa aataatg
//
LOCUS       DAFBSV010000082        12579 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.083, whole genome shotgun sequence.
ACCESSION   DAFBSV010000082 DAFBSV010000000
VERSION     DAFBSV010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12579
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.083"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            1..2373
                     /locus_tag="LLB18_002236"
     CDS             1..2373
                     /locus_tag="LLB18_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245220.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKERSEKGKENLLPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKQRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAEQKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNSFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2434..3903
                     /locus_tag="LLB18_002237"
     CDS             2434..3903
                     /locus_tag="LLB18_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBK5245221.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKHERQNF
                     LVGDDRLDHAVAFLWKDPQTGETVGASYQGTIVDFNRFGKRGTYKHIDKNPTPNHGFN
                     LKIGDPKHLKFFESSIDLLSYAALNREKLQDAWLVSMDGLKHHVISHYVEESISELRR
                     KQTFPQSIEICVDNDRAGHIFYEKEQMKGIVDPFTNKKIRCERGIPNDWQVPKEYKAT
                     YEAVAKEMSVEPEAIMAIHKTETNLQLTNQLVSAHDVQSTFGKMLAKGEPVETIDLKE
                     ACTTVAKELKVCERADGTYNFDRFYSRKANIKDVNAGILLSYKAEQYYKGYKKHEHEF
                     VPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3914..5923
                     /gene="topB"
                     /locus_tag="LLB18_002238"
     CDS             3914..5923
                     /gene="topB"
                     /locus_tag="LLB18_002238"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBK5245222.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFTGETVIT
                     YGFGHLVELDSPDMYDEKWKQWALEHLPIFPNQYHYHVPKDKKKQFSVVKRQLQSADT
                     IVIATDSDREGELIAWSIIQQAGANQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEVQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEAYLKEKGVQLGKQPGTILQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIEKVPLDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKRSEGFI"
     gene            6039..6188
                     /locus_tag="LLB18_002239"
     CDS             6039..6188
                     /locus_tag="LLB18_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245223.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6269..6865
                     /locus_tag="LLB18_002240"
     CDS             6269..6865
                     /locus_tag="LLB18_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBK5245224.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPERTLCDIWNPWYTVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            6878..7777
                     /locus_tag="LLB18_002241"
     CDS             6878..7777
                     /locus_tag="LLB18_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBK5245225.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNEIFSTPTKEDIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKERKLAYQRHQQMNREMER"
     gene            7780..7911
                     /gene="ssb"
                     /locus_tag="LLB18_002242"
     CDS             7780..7911
                     /gene="ssb"
                     /locus_tag="LLB18_002242"
                     /inference="COORDINATES: protein motif:HMM:TIGR00621.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBK5245226.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGN"
     gene            7933..8265
                     /gene="ssb"
                     /locus_tag="LLB18_002243"
     CDS             7933..8265
                     /gene="ssb"
                     /locus_tag="LLB18_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBK5245227.1"
                     /translation="MIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEV
                     VADNFQLLESKAATESRAHADQSSTSPSTATFEQRNTATPNNNGLNASQNPFGGQSID
                     ISDDDLPF"
     gene            8310..8543
                     /locus_tag="LLB18_002244"
     CDS             8310..8543
                     /locus_tag="LLB18_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245228.1"
                     /translation="MDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVFVYLVCSYL
                     LKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(8702..8824)
                     /locus_tag="LLB18_002245"
     CDS             complement(8702..8824)
                     /locus_tag="LLB18_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HBK5245229.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            9014..9238
                     /locus_tag="LLB18_002246"
     CDS             9014..9238
                     /locus_tag="LLB18_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245230.1"
                     /translation="MIKTQPLLVRFTLRTSHEPINCVVANIEIADKLLILEEGKYTIS
                     VTGHFNKRKQLVIESMQIRNPDHFTRSMSI"
     gene            9681..9887
                     /locus_tag="LLB18_002247"
     CDS             9681..9887
                     /locus_tag="LLB18_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBK5245231.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9887..10138
                     /locus_tag="LLB18_002248"
     CDS             9887..10138
                     /locus_tag="LLB18_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245232.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEVLLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENLETYENEYWLTKLEN"
     gene            10154..10309
                     /locus_tag="LLB18_002249"
     CDS             10154..10309
                     /locus_tag="LLB18_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245233.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKEKLSV
                     AVEEMIE"
     gene            10319..10591
                     /locus_tag="LLB18_002250"
     CDS             10319..10591
                     /locus_tag="LLB18_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245234.1"
                     /translation="MNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQ
                     ALELTYAKFIETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            11036..11215
                     /locus_tag="LLB18_002251"
     CDS             11036..11215
                     /locus_tag="LLB18_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245235.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDVPALKK"
     gene            11274..11630
                     /locus_tag="LLB18_002252"
     CDS             11274..11630
                     /locus_tag="LLB18_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245236.1"
                     /translation="MLKTKKNSYKLKLSILSIICLLGMIISGHLYRVAYTQFIEYKVH
                     SLGLAGDRYVEYVHYSLKCSSYILLWLIFSLFELLNLIAISSYHLDKLNTKSSRYNEV
                     FKENVKLESDLNKLKK"
BASE COUNT         4642 a         2071 c         2612 g         3254 t
ORIGIN      
        1 atggcagaag aaaaagaacc actagacaat agtcgtttgg gaaaatccaa aagaaaatta
       61 gtacgattgc aaaatgaatt aaatgaacaa atcgaaaaga tgtttgaaca ccaaaaaatg
      121 acgaacggtc aaccaatgaa cgacaagagg aatggccgtt catggtttaa ccagcaagaa
      181 cgaatcgaaa ataaagtcca aagtctgaga gaagagatca agcaacaaga aaaacaggta
      241 gaaaaacttg aaagacaaga agagctaaag gaaatgggct ataacaagta cggcggcctg
      301 gatatgacaa tcgaaaatat tccaagaatc aaagaagaaa tcgaacgctt tgaaaaaggt
      361 gaatcgactt tttcagccgc tacgatccga aaataccaac ggaaattgga aacattagaa
      421 cagctgaaag aaagatcaga aaaaggaaaa gaaaatcttc ttcctgaagt acaagcaatt
      481 attgacagcg gacgagtgac gcaatggaaa aaaaatccaa ccatttattt tttgaaaggc
      541 tatcgaaaag ttgctttaga actgaatgaa aacgggggat ttgaggaatc aaaaaaatac
      601 caagccacgt cggaagagga aaaagcagct gttcgtgaat tacttgaaga ggctgcgcca
      661 actgattctt tgaaggagaa agaaaacgat catttctatc gagtagaatt caacgaaaat
      721 gatccagaaa aaggattgaa aagttatggt ggggagatcg taacattcga attgatcgat
      781 caactcaaaa cgttggataa ccaatacgcc gcagaagcag gttattataa attctatttt
      841 gaagaagtga agaacggaga agtagtcgat cagatccgaa tggatctagg ggatggcgtc
      901 aacagtaatc aacccatcta tttagagtta gcaaaattgt gcgaacaagt acctgagaag
      961 gaacaaaaac aatcggtcaa aaatgaacct gtttcaaaag aacaaatgca gtcgaaagaa
     1021 acaaaaacaa aacaaaaggg ctatcaaaaa cgaacggcag aagagattaa acaagaagtt
     1081 aaatcccttt cgcaacaggc actggatgcg gtgaaaaagc atacccattc tcctgaagac
     1141 gtcaaagaac ttttgaactt tatgtctcgt tttccagaac gatcctttag aaatcaatta
     1201 ttgattgagg aacaatttcc aggtgcaacg gcttgtttag gtcgtgccgc gttgaaaaaa
     1261 gaaggaatct atatcaaaaa aggggaacaa gggaacaaga tctttgtcag aaaaacggtc
     1321 aaaggatttt atgagaaagg acgtggcttt gttcgagaaa cagaagctac accagaagat
     1381 aaacaacgaa ttgaaagtgg tcaaatcgaa gtgatcaaaa aaccttacta cacgattgaa
     1441 aaagtgtttg atatcacaca aacacagtta aaacctgaag attatccgaa aatctttccg
     1501 aaccgtgtct ttgattttca attggataaa aaaggacagt cagaacttca agctgggatt
     1561 caagcggtag ccaacaatat tggaatacaa attcgagata tgacagaaag tgaagtctat
     1621 caaagagaat taggacaagc acgtggggcg tatgttcgta acgaatttac tggcgaagaa
     1681 gaaatcgtca tgaatactcg aaatactcct acgcaacatt tagctacaag tattcatgaa
     1741 ttagcccatg caagaatgca caaattttca gaattagata ccgcaactaa agaattgcag
     1801 gcagaaatga cttcttatat tgtgtgcaaa cattttggaa tggacacgtc ggagaaagct
     1861 attccttata ttgcagcatg gacgaagaat ggtcagacgt tggatgataa ggaagctgcg
     1921 gaacgtggga aaatcatgaa tgatgtcagc cgtgtcgcaa atgaattcat tcaaaccatt
     1981 tctaatgaaa tcaatcaata cagagaaaga gaaccagaga tccaaccagc agaagtgaag
     2041 caggagcata aaaatactgt agaaacggca gaacaaaaga atattgtgcc tgttggttca
     2101 ctttggatcg acaagaaaga cgggaaagta atggaagaag atacgggtcg aacgttacat
     2161 ttgaaggatg cggcgtttat tgaagatcca cagcataatc aagtaatttt aaaaggaaaa
     2221 agttatggaa aagagatcca aacggcgtta ccttcagaag aatttgcgct aggaaattca
     2281 ttccgatttt cacttgagac agtgtcagaa gtggcaaaac gaaaaaatga aatctattat
     2341 gaacaacaat tgtcacaaaa agaacgtgta taaaacaagt aaaaaagact atctgaaaaa
     2401 cggatagtct tttttctttt gggaggtttt aaaatgaccg agaaaaaaat gagtcttatt
     2461 gatcgatgta aacagatcga tatagtggat tttgctcgaa acaatggaat ggctgtagtc
     2521 aataaaggac gagactatcg cttagaagac catgattcat ttgtttttga tcgaagaaaa
     2581 caacgttttt attggaacag tcaaaatatt agtggcgaca ttattgaatt agctaaactt
     2641 tttttcatag acaaagagat ccaagaccct aagcaacaat ttaaagcagc cactgatttt
     2701 attctaaaga atgaagacaa aacagaacga gtggaaaatc ttcattttga gacagaaaag
     2761 tacaaagatc accccgttga ttatcaacca ctcacagaaa aaggaaggaa ttatctgaag
     2821 gaagaacgaa aactaccaga gtggctgatt gattatgcag aaaaagaagg gttgattgct
     2881 gaactaaagc cgaaacatga acggcaaaat tttttagttg gagacgaccg tttagatcat
     2941 gcggttgctt ttttatggaa agatccacag acaggagaga cagtaggggc aagttatcaa
     3001 ggaacgatcg tcgattttaa tcgtttcggt aaacggggaa cgtataaaca cattgacaag
     3061 aatcctacgc caaatcacgg atttaattta aaaataggcg atccgaagca tttaaaattc
     3121 tttgaaagta gtattgatct gttaagttac gctgcattga atcgggagaa actacaagat
     3181 gcctggttag tttcgatgga cgggttaaaa catcatgtaa tcagtcatta cgttgaagag
     3241 tcgatttctg aattaagacg aaaacaaaca tttcctcaat cgattgaaat atgtgtggac
     3301 aatgatcgtg caggacatat tttttatgaa aaagaacaga tgaagggaat cgttgatcct
     3361 tttaccaata agaaaatccg ttgtgagcga ggaattccaa atgattggca agtacctaaa
     3421 gaatacaaag ctacttatga agcagtcgca aaagaaatga gtgttgaacc tgaagcaatt
     3481 atggccatac acaaaactga aactaattta cagctgacaa atcaattggt gtctgctcat
     3541 gatgttcaat ctacgtttgg aaagatgttg gcgaagggcg aaccagtaga aacaattgat
     3601 ttgaaagaag catgtaccac ggtcgcgaag gaactgaaag tatgtgaacg cgcagatgga
     3661 acatacaact ttgatcgttt ttatagtaga aaagccaaca taaaagacgt taatgcagga
     3721 atccttcttt cctataaagc agaacaatac tacaaaggct ataaaaagca tgaacatgaa
     3781 tttgtacctg aagtgaaaaa ggattggaat gatcaattga agcatgagat ccagcaacaa
     3841 gaaatcagaa agcaaaaacg tgcgatgttg tttcaacaag gcagacaaca agaaagggag
     3901 tgaagtcgtc actatgaaaa ccgtcatttt agcagaaaaa ccgtcacaag cgaaggctta
     3961 tgccgatagc ttttctaaag ctacccgaaa agatgggtat tttgagatcc aagatcgatt
     4021 gtttacagga gaaactgtga tcacgtatgg ttttggtcat ttagtcgagt tagattcgcc
     4081 cgatatgtac gatgaaaaat ggaaacaatg ggcattagaa catttgccta ttttccccaa
     4141 tcaataccac tatcatgttc ctaaagataa gaaaaagcag tttagtgtcg tcaaacgaca
     4201 gctgcagtca gctgatacga ttgtgatcgc gactgatagc gatcgtgaag gggagctgat
     4261 tgcctggtca atcattcaac aagcaggcgc caatcaagga aaaaccttta aaagactttg
     4321 gatcaactcc ttagaaaaag aagccattta tcagggattc caacagttac gagacgcaga
     4381 agagacctat ccaaaatttg aagaagtaca agcacgtcag atcgccgatt ggttaattgg
     4441 gatgaacggt agcccactgt atagtttact cttgcagcaa aaaggcatac caggaagttt
     4501 ttctttaggt agagtccaaa ccccaacact ctatatgatt tatcaattgc aggaaaagat
     4561 tagaaacttc caaaaagaac catattttga aggaaaagcc caagtaatcg ctcaaaatgg
     4621 cgcatttgat gcgaagcttg atccaaatga aacccaagcg acacaagaag catttgaagc
     4681 ctatttaaaa gaaaaaggtg ttcaattagg aaaacagcca ggtacgatcc ttcaagtcga
     4741 aacagagaaa aaaagtgcgg ctagcccacg tcttttttct ttatcgagcc ttcagtctaa
     4801 aatgaatcaa ctcatgaaag ctagtgccaa agatactttg gaagccatgc aagggttgta
     4861 tgaaggaaaa tatctaagct atccgcgaac ggatacccct tatattacgg aaggggaata
     4921 tgcgtatctg ttggatcact tagacgaata caagcatttt ttaaaagccg aagcgattcc
     4981 gactcctatt catacaccga atagtcggta tgtgaataat aagaaagtcc aggaacatta
     5041 cgcgatcatt cctacaaaaa cggttatgac agcagcggct tttgaacaac taagtccact
     5101 gcagcaggct atttatgaac aagtgttaaa aacaacggtg gccatgtttg cggaaaagta
     5161 tacctatgaa gaaacaacga tcttgacgca agttcagcag cttcagttaa aggcaatcga
     5221 aaaggtgccg ctagatctag gttggaagaa gttatttgga aaagagagcg acggaaaaga
     5281 gaaggaagaa gagccgctac ttcctaaagt gacaaaagga gaaatggtga cggtggatct
     5341 acaagttctt gaaaaagaaa ccaagccacc acaaccttat accgaaggta cgttgatcac
     5401 tgcaatgaaa acagctggga aaaccgtgga tagtgaagaa gcgcaatcca tattgaaaga
     5461 agtggaagga atcggtacag aagcgacacg ggcgaatatt attgaaacct tgaaacaaaa
     5521 ggaatatatc aaggtagaga aaaataagct cgtggtgacg aataaaggga ttttgctttg
     5581 ccaagccgtg gaaaaagagc cgctgcttac gagcgccgaa atgaccgcca aatgggaaag
     5641 ctacttgtta aagatcggtg aacgaaaagg aacacaaacc acttttctag ccaatatcca
     5701 aaaatttgtc tctcacttat tggaagtcgt accagggcaa atccaatcca ctgattttgg
     5761 atcgacgtta caagaagtga aagcagccag tgaaaagcaa gaagccgcgc gtcatttagg
     5821 aatttgtcca aaatgccagg aacaagaagt cttactctat caaaaggtgg cagcttgtac
     5881 gtctgaagcc tgtgatttta aaaggtcaga agggttcatt tgaagcaacg attgttttaa
     5941 aagaagactt cactacaggc tttgaatttt ctgaaaagaa aaaaacgaac ttcaagaaaa
     6001 gaacacgccg cactgcaaaa taatggaggg ttaatcttat gcgtaatacc acacacaaac
     6061 aacaagaaat cgaaaatcaa aaagccaaaa ttcgttcaga acaggaaaaa atgcgtgcca
     6121 gcaaacgaag actgcagcaa ttgaagaacc agcagaggat tcaaaaagaa atcgaattag
     6181 atcgataaaa tcttcctaac tattgtatac gtataaactt atgttatact gtttttataa
     6241 gtttatacgt atacaaagga gggagaaaat gacaaaagca atggtataca agctgctaga
     6301 agaatttaat ggaactttgg ctttgaagga tgccaaaaaa gcgggcattt ctcctgtaac
     6361 gatcaaacgt atggtagatc gaggggagct ggatcgagag tatccaggtt ttttcacctt
     6421 acctggtcaa tttcctgatg aattgtttat ggcgcaaaaa aaatatgaac gcggcattat
     6481 ttcacatatt accgcgttag atttgtatga tttaacagat atgatcccta gacagatcga
     6541 tctgactgta ccttacggtt atcacgtttc tgaaaaagga ttgaaggaat tcgcagttga
     6601 gctacactat acaaaagcgg aatggtatga attaggtaag attgaaataa aaagtcgcta
     6661 tgggaatcct attatagctt atgatccaga aagaacttta tgtgacattt ggaatccctg
     6721 gtataccgtt gaggatgaaa tcaaagtaaa agcaatcaaa aactatatgg agtcggacag
     6781 aaaaaatctt agaaaattga atgagtatcg acgaatttta ccaacagaca aaacgatgcg
     6841 ttcttatatt atggctttaa attaaaggag aagatacatg acacctacgc agttaaaagc
     6901 aaaagtgaag aatatttcta gagaaaaaga agttgatccg cagcttgttt taagacattt
     6961 tatgatggaa aaattcttgg aaaaaatctc agagtctcct tatcgtgaaa attttgtgtt
     7021 aaaaggcggc ttcttgattg gctcaaagta tggcattgaa aatcgcacaa ccaaagatat
     7081 tgatacgact ttacgggaaa tgaaagtaac caaagaaaca ttaacaacgg ttctaaacga
     7141 aattttttca acgccgacga aagaagacat tcaatttgag attcaaggaa tgaaagaaac
     7201 gagagaagcc gattactatc caggatttag cttacgtgtg ctggcacatt tggaaaacat
     7261 gcggccagat tttaaggtag atgtgactac aggtgactcg atctatcctg caacgatcac
     7321 tcacagtcat aaattgatgt ttgaggatcg aacgattcct ttggaatcct atcctacaga
     7381 acaaattatt gctgaaaaat taagtgcaac ctttgatttt ttaacagata attcgagagg
     7441 aaaagatttt tatgatctct atactattcc taaaatggag aagatcgatg agaagacctt
     7501 gaaagatagt gtgagaaata catttacacg tcgaggaaaa actgatccgt taaagatata
     7561 ctatgaaaag gatatggatg tactgaaaaa tagtcacgag ctaaaagata cctggaagaa
     7621 atatcaaaaa agcaatcctt atgctgcgtc gatcacgtac gatgagacaa tggattcgat
     7681 tagtaatttg atggaaaaag tgattcacgt cgaagaaaaa gagcgaaaac tagcttatca
     7741 aagacaccaa cagatgaata gagaaatgga gagataaaga tgattaataa tgtgacatta
     7801 gtaggacgct taaccaaaga tcctgattta cgttataccg caagtggtac tgcagtagcg
     7861 acttttaccc tagccgtcaa ccgaaatttc acgaatcaaa acggcaattg agaagccgat
     7921 tttattaact gcgtgatttg gcgcaaacca gcagaaacaa tggcgacatt agctaaaaaa
     7981 ggtagcttga ttggtgtagt tgggcggatt caaacgcgga cttacgacaa ccagcaagga
     8041 caacgtgtat atgtgactga agttgtagca gataactttc aactattaga aagtaaagca
     8101 gcgacagaga gccgtgcgca cgctgatcaa tcgtccacca gtccaagcac cgccaccttt
     8161 gaacaacgga atacagcgac gcctaacaac aatggattga acgcttcaca gaatccattt
     8221 ggtggacaat caatcgatat tagcgatgat gatctaccgt tttagtttga gaaagaagga
     8281 gtaagcatgg caaaaaaatt agtctgacga tggatctatt gatacccgta attgcattta
     8341 tagacgggat ttctttgggc gtcactgaaa atcctttggt aaatagaatt gcgaaaggat
     8401 cactatttct tgtattcgtg tatcttgtct gttcttatct tttaaaaaga gcaggaaagg
     8461 ataattcctt ttggcgattg actaaagtca cagtagcagc gacagctgtt atacttacgg
     8521 ctattctacc gctttatatg tagagttaac gggaaatcgt tgaacttctt gcgaaatatt
     8581 gctataatga acatgaaaaa gaggagttgc gctaacaacc cctcattaac agcaccgatt
     8641 aaagaacggt ggcagaatat tagttatttg gaaataaccg ctgacctgct aaagtagacg
     8701 gttatttctt tttgtcattt ttaagcatat ttacaatcaa actaatcaaa gcaatggtaa
     8761 acataccaaa accaagaatg gtttgaattg tctcatatgc ggacaaaagg cttactcctt
     8821 tcatagattt tagcacttac attcataagc accaccacct ttccagaagt cgccaccgtc
     8881 ttcaaacttt actgtcttga ctattatagc atatctaaaa tcgaataaaa attctcaatt
     8941 ttagctgttt ttgctataat tttagcgagg tgatcgtgat ggaacaatat attggtttac
     9001 tcgataaatt agggtgatca agacacagcc attgcttgtg cgatttacat tacgcacgag
     9061 tcatgaacca atcaattgtg tagtggccaa tatagaaata gcggataaat tgctgatttt
     9121 ggaagaaggc aagtatacta tttcagtgac aggtcacttc aataaacgaa agcaactagt
     9181 cattgaatca atgcaaatta gaaaccctga tcattttacg cgatcgatga gcatataaaa
     9241 gaagagctgc agtcctaaat gaggattgta gctctttttg ttttacatag aaacagtaaa
     9301 aatgaaaagg cctgtttagg aaggcacaag cgccttctca attgaaagac ctttctctca
     9361 ctccaaccgc caccgccgtt cgagaagaaa ggaagtgaac gctacgcgtt cactaagata
     9421 aagggtcttg catagcaaga caaaatagaa aaaatttcct ctcaccaaaa ggttcgctcc
     9481 tgttcgttat ctctttattg atttgtcaga ccggcaacaa gttgcctttt atcaccaaaa
     9541 agcgacaagg acaagggtaa atggcacgct gcgcgccctt gtcttgtcgc ttttcgttga
     9601 ttcattctgg ccaacaaatc aataaagaaa gaactaacga aaggaagtaa aacctttcct
     9661 aagaggaggc agaatcaatc atgcgaaaga aatttgatta ttggggtgtt cccttcagcg
     9721 aattattccc aaactatcat gcaccacata ctgtcgaatg cgattgtgga gaaagagcga
     9781 aatgtatcaa aagctattgt ttgtatcaat gtccaacatg cgggaaaaaa tataccttgt
     9841 cttatggcga ttatatttta attgatgaga aaggaaagaa acgctgatga aaacacaaca
     9901 caaattattg actgtaaaag aagtcgttca aattttggtg gacaaagaag tcatttctga
     9961 aaaagtagca gaagttttac ttattccgcg gtactggacg atagaaaccc ctttagtaga
    10021 ggatgcaccg actatgctat ttgaagacct agtgaagatt gcaggatatg aactgcatta
    10081 tcaagaaaac ttggaaactt atgaaaacga atattggtta accaaattag agaactaaaa
    10141 aggagaaaaa aatatggctc aaaattacta tgacgaattt gtcaaattac ctttggataa
    10201 aatggcacaa aaaatggagg atatgacgtt cctatacaac gaaacacgtg ttccaaaaaa
    10261 acattataaa gaaaaattgt cggtagctgt ggaagaaatg attgaataag gtgtcgaaat
    10321 gaatcttatt gcgacgtact atcgaacact ggaagaactg aaaaagcaaa atgcaaaatg
    10381 gtttttccaa gccttactat gcttggaagt aggtgtcaaa ccaagcacta ttaaaccttc
    10441 tgaataccaa gctttagaac taacgtatgc gaaatttatc gaaacgaaaa aagccaagac
    10501 tgtttcaagt gaatggttag attattttga aaatatcaat aagtatggcg catattacac
    10561 catgaaaaag gaagacaacg aaaatgaata aggtgattta tcaactaaca acggattcca
    10621 tatcaacgat ttgaaagaaa aaaaggtcaa taatcattta taccgaaaag tgagaatgtg
    10681 tgaaacaagg acaaaaaaag cctagtaact aaggaaatgg ttcttatttc gcaccaatcg
    10741 ctccaaccgc ccccgccgct taggtggtgc gaaataaacg ggcaaagccc gataacttaa
    10801 gagaaagaag gtgatccatt tgaacaagat tattccctta ttgttagtac tgtttgttgg
    10861 cgaaatactt atgcgagata gtgcagctgt acagttaaac ctcgctgtat ttttggtaat
    10921 actggtgttt tgtttgatct tttggcggtt tgtattagtc ctcgtgagtc tactattcaa
    10981 gatgattgca gccatatttt tcatagggtt atttcgatga aaggagtgag taccaatgcc
    11041 aattgcaata ggaaataaac ggttacccgt gacattagat gaaaagagac aaaaagaatt
    11101 gcagcaacta aagcagaagt atggcaaaag tgaatctaag attatgtgta ttgcgttaga
    11161 tctattgatc gcgcaagaaa aagcaggatt tgatgtacca gcgctaaaaa agtgacgtca
    11221 ctttttaatt tgatctatat aagtgatatc acttttacca aggagggaat taaatgttaa
    11281 aaactaaaaa gaattcgtac aaattaaagc ttagtatact atctattatt tgtcttttag
    11341 gcatgataat tagtggtcat ttgtatagag tggcatatac gcagtttatt gagtacaagg
    11401 ttcactcttt aggattagct ggggatcgat acgttgaata tgtccattat tcattaaaat
    11461 gttcttcata tattcttctt tggcttattt tttcattgtt tgaattgcta aatttaatag
    11521 caatatcttc atatcactta gataagctaa ataccaaatc tagccgttat aacgaagtgt
    11581 ttaaggaaaa tgtgaagtta gaaagtgact taaacaagct aaaaaaataa aaagaagaaa
    11641 acataagtta actaaaatta ttttattaag aatgatggaa tataaggata aggttaccaa
    11701 cataacgatc attacttctc tgatatgcta tggacttcta tcaatcagta ttttgtctat
    11761 agattatgga gtaactatac tgcaagcctt agttttggct atgcctatgt atctatcttt
    11821 gtttatcatg catgaaatat ataagctatt tgttttatca aaaaatgtag aaatacgggt
    11881 aaatattttg gtgaatagtt atcaaaaaga actcaaagaa agaagacggt ggcggtattt
    11941 attgaaagga tgaaaaagta ggatttgaca tactggtatt cagaaagtgc cgtcactttt
    12001 aaaacaatgg aaaaggtgga gataagatga agaaaaaaca aactaaacta tcattagcag
    12061 atatttaaca cagttaaccg caactgaaga tggtgttgtt gaatttgaac aatctgaaat
    12121 tgcggtagta gatgatcgtt accttaaaat gccttacttc tttgaccaag caaaggtcat
    12181 ttgcctttgt cactacgatg gggtacgtga ttttaggcgt taaaaagtag tgattatatc
    12241 aactttacga gtaaatataa atttagacat gaaactgaat tatccaatgg aaaatcatgg
    12301 tttataatct agaaaaatta tagtaatgat tggattatat atattctttc gtattttcgt
    12361 acaactgtag cttgtcaaaa ttgagaaatt taaccgatta ggtactttac atcgttattt
    12421 gggtaatttc taaaacatga agcttaccaa cgaataaact gagactatct tattaattga
    12481 tcaatataag aaaatatctt tgaggagatg atgtactatg ttttcgtcta tccacgattg
    12541 gttaggtggt cttttcggcg gtggaggtaa aggttttta
//
LOCUS       DAFBSV010000083        12077 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.084, whole genome shotgun sequence.
ACCESSION   DAFBSV010000083 DAFBSV010000000
VERSION     DAFBSV010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12077
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.084"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            452..703
                     /locus_tag="LLB18_002253"
     CDS             452..703
                     /locus_tag="LLB18_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245237.1"
                     /translation="MKEKPVNKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
     gene            737..1015
                     /locus_tag="LLB18_002254"
     CDS             737..1015
                     /locus_tag="LLB18_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245238.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            1612..1869
                     /locus_tag="LLB18_002255"
     CDS             1612..1869
                     /locus_tag="LLB18_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245239.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            1982..2593
                     /locus_tag="LLB18_002256"
     CDS             1982..2593
                     /locus_tag="LLB18_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245240.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            2772..3329
                     /locus_tag="LLB18_002257"
     CDS             2772..3329
                     /locus_tag="LLB18_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245241.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(4028..4549)
                     /locus_tag="LLB18_002258"
     CDS             complement(4028..4549)
                     /locus_tag="LLB18_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBK5245242.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            4748..8440
                     /gene="nifJ"
                     /locus_tag="LLB18_002259"
     CDS             4748..8440
                     /gene="nifJ"
                     /locus_tag="LLB18_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBK5245243.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            8629..9516
                     /locus_tag="LLB18_002260"
     CDS             8629..9516
                     /locus_tag="LLB18_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBK5245244.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            9513..10682
                     /locus_tag="LLB18_002261"
     CDS             9513..10682
                     /locus_tag="LLB18_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245245.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            10706..12061
                     /locus_tag="LLB18_002262"
     CDS             10706..12061
                     /locus_tag="LLB18_002262"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBK5245246.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
BASE COUNT         4020 a         2029 c         2653 g         3375 t
ORIGIN      
        1 caggcgtaat gcttttttct agtttctatt tatttagtaa tgctctatta gcacagcgag
       61 ggaaatataa gtttaaaata ttagattaga tattattttt agaggggata aatataaaat
      121 gaaaagaggt tatttataat ggaaaaagta ttaccaatta agagctactg tattccaagg
      181 cttttcatca tagaatttca aaagtaaaga catgtgtttc acaaatagtg tctatcctgg
      241 ctaaataatt cttccactat ctgctttaat ttcagtagac ttttcggcaa gttatttgct
      301 aatgagatga atagagatta caactcgcct ataaccgctt aaaacaagct tttttaaagt
      361 atagttagca agtcgtattc atatgttcaa agaggagggc ttatgaactt tgaattcatt
      421 ccgtgtgaac agaacagtag ggggaagtaa aatgaaagaa aagcctgtaa ataaatggtc
      481 attgtataaa aattcaatgt ttggagttgt tatctttggt gtttgtgctg gattattcct
      541 tttcatatta ttacaaacgg tgactctttt ctcttctaat cctacttatg gatggagaga
      601 cagtatagcc ttagggatgt ttgcgggagg atatggattc ttattgttgt tctcaattct
      661 cacactaagt ccaatccatg gactcattca actttggaag taagaacgag ccttaaactt
      721 ttcgttctcg gaagaaatgg aaaaacacaa cataacaggc agtatgtatg tggatgatca
      781 atggtttatc agcactgatg aggtaaaaat agctgccatt aggagagatt acctgcagaa
      841 aattcataaa ataaaagatc ctaatgggaa aaaggcaagg ttaattataa ctttgataac
      901 atctaatggt aagaagttaa aacttgcagg atcatatgat aatgttaaaa agttcgaaca
      961 ttggtatctg caaaaagaca gcattagtct taataaacaa tttgaaaaaa attaatcaaa
     1021 gtcatcggca acacgaataa tttgacatct tgatattgtg atataagcaa aaacagcatt
     1081 tctgagaccg aacagcataa aaaatttaaa tgttggaatt tatataagca aaacccaaga
     1141 agctagatgc gatagagcat ttaatttctt ggggttttgc ttgggaatca gcatatcaat
     1201 taaaatgatc atctcggtat ttcaaaagtg ggtacgatta caaatagttg gagcaaaata
     1261 gtgggtaaaa ttaccattcc agtgtctgtc ttgcctcttt ttcgtcaatc acaaatagac
     1321 gagattcata ggaaaaatcg atacagggta tgatttcaat gatattatga ccaattacaa
     1381 aatagattga taaagcattt tttgcatttt tataatagtt tattgataat aatgtatgag
     1441 atacagtata atgatttaaa aggtaacgtg ttgtgaccga attaaatgaa ttaatgccta
     1501 ttttttatat tccttagtgg acaaaaatgg agacagtgaa gttaggagca ttgtatcctt
     1561 tgttgcgtag ttcaaaaaag taagcgattt ctataatggt cagggtaaac ggtgagggct
     1621 gtccacgtaa atcctactat tgaaatcaca atgatcggac attcaaaagg tggtgctgaa
     1681 gcagcaaatt cagtagctat aaatacgaat gcgattatat ttaatccagc gacagtaaat
     1741 ttatctgctt atgaattaga ctcaaacaca tatacagcaa acatggtagc ttatgttgtc
     1801 gagggagatg cattaaatgt tgtttttgga ggagtataca cctattggag aattaatcat
     1861 gttagataga caatatgatg caccttagtg gagaatgata tctcgcatag gtaactcagt
     1921 aaaaaatcaa ggtatggaag caattatctc tgcattggaa gatcgatata gataggcgga
     1981 tatgaatagt aataggggga ataaaatgga atacaatgga tcaatgagaa ttgtacaaat
     2041 tatattttgg attacatcgg gaattgtgat cataggagga gtttttttga tgttgccaag
     2101 cttaatattt cctttctttg cattaatctc acctaaaata cccgaaccgg aaatcaccta
     2161 tggagaattt ccatttagga ttgaatacga actagatgga cagattaaca taattgaaga
     2221 tactgtcata gctgagttta acgggtgtga gttcagcgca ggttctatga aaagagaacg
     2281 aagatggaga agtagattag ctagtggtag agaagatcta ccttttgggg acgatctagg
     2341 aatctatttt agtcgaggaa gtgcgcaata ttatatgggg gaaaatgtac aatcaatgtc
     2401 attaaaacca catatagccc ttagaaatct cgaggaaggt tttaaaagag aggtagactt
     2461 tatattagga gaaagtggat acataagaac tgtacttaat ttcggagaag cgcaagaagt
     2521 tttgacacaa tacggaatta ccttaatcaa ctgggaaata tctgaaccga ttgttaacaa
     2581 ttttggtgat tagaaaacaa ttacgataaa tagaaacaag ccaaatcatc agcaagtaaa
     2641 agctgatgat ttggcctttc ttatacgagt agtaggaatt catagcgaat attattacga
     2701 ccagtagata ttttgatatt aaaggagtat tacgaactaa tatgtgagaa tgtagaggtg
     2761 atgtgcgaat aatgagaaat ttatcaaata gaaacaaaat attaatcatt attgttgtta
     2821 tagctgtgtt tcatctggga acgaatgcgg ttttaagtag aataatattg ggtcctaagc
     2881 caccaagacc agaaattacc cgaggggagt ttgattttag attagaatat gaagtagatg
     2941 gggaaaggat tgtgatagaa gatacaattg ttgcattatt tgatggattt tctgcagatg
     3001 caggtagcat ggcatggtat cgcacgtggc gtctacattt agcaagtgat agacgatcac
     3061 gaaatatctt attagatgaa ttagaggatg gtcgaagaat atattatgtc ccagaaagtg
     3121 ctaactattc tatgggagat gtacagaaaa aaagagagcc taatcctaat tggtatccat
     3181 ttaatggcgt aacaatagaa tatccacgca ataaaacacc tgaaataggt gcaaaattta
     3241 taagtggttt agaagatctg tacgataggt ttggaatccg tcttattagt tgggaacacg
     3301 atccaccaat agaaaatcgc tttgaataat cgaaatctac taatccattt catcagccag
     3361 tgaatgttgt aatggaacaa tttggtttag tgttcaaaac cattgaaata ctaggctgtg
     3421 atcagcaaaa atgaatctga ataaaaaaga gagcaactat tagctgagag gagttaatag
     3481 ttgttagctt tatacgaatc aaagtggcaa atacagatgc gtatgcattt gtgtttgcca
     3541 tcttgcgttt ggtagacgag ataggtataa gctaaagaaa caacttgttt aaaataaacg
     3601 acctagctca acaaatgacc atctaatcaa ctaacagcat acataaaagc aactattttt
     3661 gaagtagaat tgaaatcggg ataacttaaa aagtgattgg gatactagtg agaatcaccg
     3721 tacataaata ttactcgtta agggaaattg agaaattttg tatgaaaatt taagaattag
     3781 ttagtatgcg caagtcaaaa atatgaataa attatttggt ggagataatt tgcttagctt
     3841 gtcataagaa atgagataat ctggcagatg caagcttttg gacaccattt attcggaata
     3901 aggaggctgg gacagaagcg tttaactcca agaaataaga aggagttgct tctgcttccg
     3961 ccgtttatac gtgtttagag cgtgagacaa aagtgttctt tacttttgtc ccacgctcct
     4021 tattttttta ttttgtttgg atcaattctt ttaattcctc tattgaaata gattcatcaa
     4081 agatttcttt acccaagatg acagttggaa caaatcgaat atgtgcttgc tcagcttcgt
     4141 tgatgacagc ttggctcagc tgttcgtctt tttgttctgt cagctttagt ttatctactg
     4201 caaaatccgc tacttcttgg agagaaagat gtttccactc gtcttgagta tcgaatattt
     4261 gtttgatctc tttgatcgct ttttggccat cgctgattgt gagataccgg tgcatcacgt
     4321 tccctcgctg taagctttct ttttctttat cgaacaattt gatcactcgc tgcaattgcc
     4381 cgctttggac tgcttcttct aatagctcat aagattcttc aaaccattgt cggcaatacg
     4441 gacaagctaa gttgatgaat tcgaccattt ttttaggagc attcgatgaa ccataaagga
     4501 ttcctttttg tgtatttgtt ttcgttgcat caatcactga tatatccatg ttaaaacacc
     4561 tctttcgctt atagtttata catgtctgac aaaaaaaggc aacgatttag actgtttgtc
     4621 taaaaattag atgaccaatt caaatagata catgtaaaat atttttataa ataaaagaaa
     4681 aaaatggcat gttttacgtt ataatggaac agataataag agagaatatg aacaaggatg
     4741 atgaatcatg cgaaaaatga aaacaatgga tggcaatacg gcagccgcat atatttctta
     4801 tgcatttacc gagattgctg caatatatcc aataacaccc agttcgacca tggctgaatt
     4861 agtagatcaa tggtcagcag caggaaaaga aaacgtattc ggtcaaccag taaaagtagt
     4921 agaaatgcaa tccgaagcag gagcagctgg tgtggtccat ggatcattga aaactggtgc
     4981 actgacaact acatataccg cttcacaagg gctgcttttg atgataccga atatgtacaa
     5041 gattgctggg gaactactgc caagtgtttt ccacgttgct agtcgggcag tgacgacaaa
     5101 tgcgttgaat attttcggag atcacggaga cgtgatggct gcaagacaaa caggatttgc
     5161 tatgttagct gaaagcagtg tacaagaagt gatggattta gcacctgttg cccatcttgc
     5221 ttctattgaa ggagaagtcc cttttttgaa tttctttgat ggattccgta cgagtcacga
     5281 gattcaaaaa atcgaagttt tggaatatga agaattagct cctctgatca atcaggagaa
     5341 attagcttca tttcgtaaac gagggatgaa tcccaatcat ccgactgtta gtggtacgaa
     5401 ccagaatcca gacatccatt ttcaacaacg ggaaacgatc aacccctatt atgataaatt
     5461 acctgaaatc gttcaaaaat atatgaaaga gatcaaccga ttacgaggaa cttcttatga
     5521 cttggtgact tattacggag cagacgatgc ggaagaagtc attgtttcta tgggatcagt
     5581 tgcacagacg attgaacaaa cgattgatta cttgaatgca aacggacgga aaacaggttt
     5641 tttgaatatc catctttatc gtccttttcc agtggaaaca ttcgtgcaaa agttgcctca
     5701 tacagtaaaa acaattgctg ttcttgatcg aagtaaagaa ccaggggcag gtggagaacc
     5761 tctcttatta gacgttcaaa gtgcgttata tgattctgaa cttcgcccgg ctgttattgg
     5821 tggtcgctac ggattggggt ctaaagatgt gactcccgac caaatctcag cagtttttga
     5881 tgaattgaaa aaagacccaa gcatacgcaa aaaacggttt accataggga tcgtggatga
     5941 tgtgacttat caatctttgg aaccaaagga aagtctggat ttgacagaac cgcaaacatt
     6001 ccaggccaag ttttggggat ttggatctga cggaacagtt ggagcaaata aatcagctat
     6061 caagattatt ggagatcaca ccgataaata tgcgcaaggc tatttttatt atgattcgaa
     6121 aaaatctggc ggtctgactg tctctcatct tcgttttgga gatacgccga tacgttcagc
     6181 gtatcttgtc gagcatgcgg accttgttgc ctgtcacaca ccagcttacc tgcatagcta
     6241 tgacttggtc aaaggattga agccaggtgg cattttttta ttgaatactc tttggagcga
     6301 cgaacaatta gaaacgcatc tgcccttaaa attaaaacgt tacttggctg aaaataacat
     6361 tagattctat acgatcaatg ccatgagatt ggcccaagaa gtcggtttgg gacgccggat
     6421 caatacggca atggaaacgg ctttttttaa attagctgac atcattcctt ttgatgaggt
     6481 gcttccgctg ctaaaagaag aagccctgaa aagctatgga cataaatcaa tggctatcgt
     6541 agaaaaaaac atacaagcaa tcgatcggac gaccgaactg cttcatcaag tcgcgatccc
     6601 agaccattgg agaacgttgg agatgcctga aaaaatcaat aaaaggaaca ctggttatat
     6661 acaagaaata cttgaaccag tgaatgcaca ggaaggaaat caactctctg ttggtacact
     6721 tgtagcaaat ggaatgacaa ctggcgaaat gcctttagga acggcttcta tggaaaagcg
     6781 gggcgtcgct ttagaagtac ctgagtggat tagtgatcgc tgtacgatgt gtaatgaatg
     6841 tgcctttgtt tgtcctcatg ctgccatccg tccattttta gcagatgaag aggaaatgga
     6901 agaagcgcca gaaggattta tcgtgagaga aatgcgaggc gcagacggcg taaaataccg
     6961 tatccaagtt tcagtggaag actgtacagg ttgtggtctg tgtgtagagg cttgtcccgc
     7021 aaaagaaaaa gctttagtga tgaagcctta tgaagaacag aaagaacaag ctgtgaattg
     7081 ggcttttgca atgacattaa gacaaaaagc aaatccagtc aaaggaaaga atactgtctt
     7141 gtctacacaa ttcaatcaac cgcttcttga attctcgggc gcttgctcag gctgtggcga
     7201 aacaccttat gtaaaattat tgacacaaat gttcggtgat cgaatgatga tcgcgaatgc
     7261 gacaggctgt tcttctattt ggggcggtgc ttctcctgct tctccttata cgaccaatga
     7321 atgtggtcaa gggcctgcat ggtcaaattc tttattggaa gataatgctg aatttggtta
     7381 tggtatgctt ctagcggcac agactcgtcg cgaggctttg gcaagttcaa tcaaagaagt
     7441 attgccaaaa gtatcagaag aactacgaga attgatggaa gactggttag tacacatgtt
     7501 tgagagtgaa ggaacgcagc aaagagcagc aaaactgcaa gctgcgatcg aaagcgaacg
     7561 atcaattttc cctgaactgg aggatatata caagagaaag gatctattcg taaaaaacag
     7621 ccaatggatg attggtggag acggatgggc ttacgacatt ggttttggcg ggatcgatca
     7681 tgtacttgcc agcggagcag acgtgaatat ccttgttttg gataacgaag tctattccaa
     7741 tactggcggt caaacctcaa aagcaacacc agcttcggca atcgctaaat tttcggctag
     7801 tggaaagtat gcttcaaaga aagatctagg aatgatggcg atgacatatg gaaatgttta
     7861 tgtggcgcaa attgcttcag gtgccaatca aatgcaaacg atcaaggcat ttgaagaagc
     7921 agaaaagtat cctggtcctt ctctgattat tgcctatacg ccttgtatca cacatggctt
     7981 gcttggcgga atgaaagaat cgcttaaaga agcaaaagaa gctgtttctt ctggttattg
     8041 gtcattatat cgatataacc ctacaatggt cgaaaaaaac aagaacccaa tgactttgga
     8101 ctacaaaaaa cctgatttct ctgctatgcc tgatttcatg aggaaacaag ttcgcttttc
     8161 ctcgctagat aacgcaaatc caaatcttgc aaaagcttta tttgaaaaga ctgtccacga
     8221 cgctaaaaca cgtttttaca actatgctgc actgacggga gaattagaaa aaatcaagaa
     8281 acgacttgaa ccagaggaat ctatcgatgt acccgttaag actagaaaag aaaaaacgac
     8341 ggaccttgaa gcagaagaaa gaagagctgc tagaagagct gccagagcag aacgacgtaa
     8401 aaaaatggaa caagctacaa aagaaaaaaa ggaaaaataa cagaaaaaat ataatgaata
     8461 attctctgaa gtttaaaaat atttattgca gagaaaaata aaacgcatac ttgcaatttt
     8521 cttgaaaatt atgcgttttt ctcaagaaaa atacgagcat atcagcctct aaaattaaaa
     8581 catatgatat actagagagg aaatctcaaa agagaagaga ggctttttat gtcatttcaa
     8641 atcggggaac tttttaattt ggactattgg cagcaaatgt tttccggtga cttgttctct
     8701 ctgaattttt tggtgaacat acttgatatt ctggttgtct ggtatcttgt atacaaactg
     8761 atccaactgc tgcgaggcac aaaagcgatt cagcttctga aaggtgtagc tatttttatt
     8821 gttatccgaa tcgtagcgga aatcattggt ctgcacacct tgtcttggct gatgaaccaa
     8881 gtcattacgt acggggtgat agctgctatc gtgatttttc agccggaaat ccggagagga
     8941 ctggaacatc ttggacgcag ttcgcttttc aaacaatcaa aaagcgaaca gcaggaagat
     9001 gagaagatga tcttgtcttt tgacaaagcc atccaatata tgtccaagcg aaaaatcggt
     9061 gcgttgatca ctatcgaacg tcatactgga ttagatgagt atattgagac agggattgct
     9121 ttagatgcag atatcactgg ggagctgctg atcaatatct ttattcctaa tacaccgctg
     9181 catgacggtg cagttattgt aaaagaagga aagatcgcag tagcaagcgc ctatcttcct
     9241 ctatcagaaa gtatgttgat ccctaaagaa ttcgggactc gacaccgggc agctgtcggt
     9301 ataagcgaag tcagtgacgc gattaccatc gttgtctctg aagaaaccgg ggacgtcagc
     9361 atcacgttag ataatgaact gatggctggc ttatcccagc aagaatattt ggcaatcttg
     9421 cgtagagaac taattgctga agagaaaaca aaaaacaaga aaaacgtgat tcaatctttc
     9481 ctagacggta tgactaaggg aggggatcgc aaatgatctc aaaagagaaa cggacaagca
     9541 ttctttacag ttttattgca ttgctgttca gtattgcgct gtacttcaat gcaaatggcc
     9601 agtccgttcc aaatacgctt tctggaaatg aagcgtataa tcaaacagtt acgggggtgc
     9661 cgatcaagat ttcttatgat tcaaagcgct actatatcca tggatatgaa aatgcagtga
     9721 ctgtcaaact ttccagtgca aaccgagttc agttgaatgc agaggcaaac gaagatacac
     9781 ggatgttccg cgtcacagca gatatcacta agctgggcga aggaacacat gaagttccgc
     9841 taaaaattca aaatttgagc agtgctgtca cagcaaagat cgaaccatcg actattacag
     9901 taacggttga gaaaaaggta ataaaagatt tcgatgtgga aacgttgatt ccttcaacgt
     9961 tcacaccatc tggatatgaa cttgatgata cttccgttag tcctaaaaaa gtctctatca
    10021 ctacaggtga caaaacattg gcagaaatca aacgagtagt agctgatgtg gacgcttcga
    10081 tggtcacaga tgatgggatt aatagtgagg tcccaataca ggcgctgaat gcagcagggg
    10141 aagtattaag tatcgtctct gatccagtgc aagtaacagt gagagctgat tcgatcaagc
    10201 caagcaagtc ggtacgactt tatgggatac agcaaggaac accagctgcc ggggtagaaa
    10261 gctatgattt cagtttttca aaactggaag cagaagtaag cggctctagc gatttgcttg
    10321 catcgatcgg tgacagtatt gctgtaccga tcaatgtctc aggtatcaat catcgaacaa
    10381 ctcgtaaaat tgaaatacca gtagaagagg ggttaagtat caagcccgaa tcagttagtg
    10441 tggagattac acccgtgttg caaacgtcaa gcagtagctc tgcttcgacg agcagtcgga
    10501 cacaagaaaa tacaagtacg agtagaagta tttcatctgc tgattcagga acggaaccat
    10561 cgacaacaac catttcttcc agttcggaat ctgggacaag cagctcgacc acaagtacag
    10621 aagaaacatc agaaacaagc gaatcaacac aaatgagcag aacaaattcc tcagaaaatt
    10681 aagttaaagg agtaatttta caactatggg taaatatttt ggaacagacg gcgtacgcgg
    10741 tgaagccaac aaggaactta cgccagaact tgcatttaag ctgggacggt gcggaggtta
    10801 tgtcctaagc cagcatgaag aagaaggaaa acgcccacgc gtgttagtag ggcgggatac
    10861 aagaatctca ggtcaaatgt tagaagaagc gctgatttca ggacttttat cggtgggtat
    10921 cgaagtgttc cagctaggtg tgatctctac accaggtgtt gcttatctga cacgtttgca
    10981 aaaagcaagc gcaggggtca tgatttctgc ttctcataat ccagcacaag ataatggaat
    11041 caaatttttc ggtgcagatg gttttaaact agtagatgac caagagctag aaattgaagc
    11101 attattagat gctgaagtgg atgaattgcc tcgtccatca gctgaaggat tgggaactgt
    11161 agaagaattt ccagaaggct tattgaaata ttctcaattc cttgtacaaa cgatcaacgg
    11221 tgacctttcc ggtttgacca tttgtgtcga tgcagcaaac ggagcaactt caacaagtgt
    11281 taatcgtttg tttgccgatc ttgaaacaga tttttataca atgggcacaa atccagacgg
    11341 gttaaatatc aatgacggcg taggctctac ccatccagaa cgtttagctg agatggtcgt
    11401 tgaaaaagga gcagatgctg gactagcttt cgatggcgat ggcgatcgta ttattgcggt
    11461 ggatgaactt ggaaacattg tcgacggtga taaaatcatg tttatctgtg ctaaatactt
    11521 ggcagaaaaa aatcgattga aaaaagatac gatcgttacg actgtcatga gtaacttagg
    11581 attccacaaa gcggtggaag gaatcggttt gaaagatgtc gttacacaag ttggtgatcg
    11641 ttacgttgta gaagaaatgc gcaaaaacga ttataacttt ggcggcgagc agtctgggca
    11701 catgattttc ttagatttta acacaactgg agatgggatg ctttcaggaa ttcagttact
    11761 gaatatcatg aaacagacag gtaagaaatt atcagagctt gcagcagagg taacaatcta
    11821 tccgcaaaaa ttagtgaata tccgcgtaag tgataaaaac ggtgcgatgg atgttccggc
    11881 aatcaaaaaa gtgattgaag aggcagaagc tgaaatggga tcagaaggaa gaatcctagt
    11941 tcgtccttcc ggtacagaac cattacttcg agtgatggca gaagcgccta ctgatgagaa
    12001 agttaattac tatgtcgata aaatcgcggc agtagtcaaa gaagaaatcg gactggatta
    12061 agagatattt tcataaa
//
LOCUS       DAFBSV010000084        12054 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.085, whole genome shotgun sequence.
ACCESSION   DAFBSV010000084 DAFBSV010000000
VERSION     DAFBSV010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12054
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.085"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            57..251
                     /locus_tag="LLB18_002263"
     CDS             57..251
                     /locus_tag="LLB18_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245247.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
     gene            241..594
                     /gene="tnpB"
                     /locus_tag="LLB18_002264"
     CDS             241..594
                     /gene="tnpB"
                     /locus_tag="LLB18_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBK5245248.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            696..2243
                     /locus_tag="LLB18_002265"
     CDS             696..2243
                     /locus_tag="LLB18_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBK5245249.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            2700..3314
                     /locus_tag="LLB18_002266"
     CDS             2700..3314
                     /locus_tag="LLB18_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBK5245250.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            4087..5826
                     /gene="yfcC"
                     /locus_tag="LLB18_002267"
     CDS             4087..5826
                     /gene="yfcC"
                     /locus_tag="LLB18_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBK5245251.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            5983..7167
                     /gene="iadA"
                     /locus_tag="LLB18_002268"
     CDS             5983..7167
                     /gene="iadA"
                     /locus_tag="LLB18_002268"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HBK5245252.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            7278..7481
                     /locus_tag="LLB18_002269"
     CDS             7278..7481
                     /locus_tag="LLB18_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBK5245253.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(7582..8244)
                     /locus_tag="LLB18_002270"
     CDS             complement(7582..8244)
                     /locus_tag="LLB18_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5245254.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(8257..9759)
                     /locus_tag="LLB18_002271"
     CDS             complement(8257..9759)
                     /locus_tag="LLB18_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5245255.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNLKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            10307..11986
                     /locus_tag="LLB18_002272"
     CDS             10307..11986
                     /locus_tag="LLB18_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBK5245256.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
BASE COUNT         3848 a         2103 c         2530 g         3573 t
ORIGIN      
        1 actaacaaat gcacctcaag atatacttga gctatcaaga agtctggagg ttttctatgt
       61 ataaattaaa tgagattgtt cctgtccaat taggaaacga aaagagtgca ccagaaaaag
      121 gtaaacccgc ggctgccaag ttagcgatgc gcatcaaaag agagaatggt tctgaagttt
      181 tgatctataa cggtattaac aattatattc ttcaagctat tttgaaagaa ctgttgtcca
      241 atgctttatg atttacttca aaccaaacat atttatattg tgtgcggaaa aacagatttg
      301 cgaaaaggaa ttgatggtct tgccagtctt attcaacaag agtatcaact cgagctttac
      361 gaagatgccg tttttttatt ttgcgggaac cgtcaagacc gtttcaaact tctctattgg
      421 gacggtgatg gttttcttct ctgttataag cggatagaaa acggcaagtt aaaatggcct
      481 cggacgaaag acgaagttcg aaccttaacg aaccaacagg ttcgatggtt gttagaagga
      541 ttaagtatcg atcaacctcg agctattttg ccaggaaaaa aaggagtttt ttaagctggg
      601 gggttaacac aaaaaatgtg ttgaacccct atttcttgtg cgtttcttgt ggtattctgt
      661 aacaaaatca gttcgattca aggtggtgaa aaattttgga aactacagat acgttgcttc
      721 agttgcttca agaagcccat aaaaccaatc aagcacaaca acaaaccatt cagaatctta
      781 caactgaaat ccaactattg aatgaaaagg tcaattattt aaccaacaaa ttatttggac
      841 gctctaaaga gactctcttt gaggaaacga atgggcaatt gaatcttttt agtgatgaag
      901 aaatttctgt aagtgttcca gaagcagctg ccaccattat tccagtaaaa ggacatcaac
      961 gagttgtagg aacgaaagca gacaaaatca aacacttacc tataacagag aaagaacatc
     1021 tccttccttt ggaagaacaa ttttgtgaac attgcggttc acagatgaaa gatatcggac
     1081 ggacaaaagt acgagaagaa attcgtttcc atcaggctat gttggattgt ctcacccatt
     1141 atcaacatac ctattgttgt aaaagctgcg aaaaagaagg actttcttct tttaaaaaag
     1201 cgatcgttcc taaacctttg atttctaata gcttaggttc caatagttta gtggcggaaa
     1261 cgatccggat gaaatttggt cagaaagttc ctgcctatcg gcaagagaac tattggaaac
     1321 aaacacatgg gttggatatt tcgagagata atatcaccaa ttggcatatt aaagcagtgc
     1381 aaaacgcgtt agacccttta ggagaacgat taagagtcta tcttaatcaa gaagagattc
     1441 tacacgggga tgaaacaagt tatcgtgtga ttgaaagtgc caaaacagat acctattact
     1501 ggcagttttg tacaggaaaa gacagtcagc atcccatcgt ttattatcac cacgacgaaa
     1561 gtcgtgctgg agatgttccg aaaacttttc tcaaggagtt tacagggtat ttacactgtg
     1621 acggctatag cgggtataat gccgtggaaa gtgtacgact tgtctattgt ttcgcgcatg
     1681 ttcggcggaa atttttcgaa gcaattccaa aaggaaagaa aaacacggat attcccgcag
     1741 ctcaagcagt caaacaattg gataaatggt ttgtcctaga aaagaaatgg aaagactttt
     1801 ctcctgagaa gcgattaagc tgtcggcaac aagaactgcg tccattattt attgcttttt
     1861 atgagtggat ggcaacgata gatcctgttg caaaatccaa gttggatgca gccgttcaat
     1921 atgcgtgtaa actacgaagt ggttttgaac ctatttttga agatggtcgt ttagaactca
     1981 caaataatcg tgcggagcga aatatcaaag agctggtgat aggacggaaa aattggttgc
     2041 attccacaag tcttgaagga gcacgaactt caggaatcat tctgagtgta tataaaacag
     2101 cagaacttaa cggattgaat cctgtaaagt atctagagtt tctatttgat aagataccaa
     2161 atcttcccgt actttcagca gaaactttag atcaactgtt gccttggaac aaggatgtac
     2221 aacaacattt ttctcgtaac taaaaacgcc aaacattccc gattctattc tataggtcgg
     2281 gttatttgac gtacaggtac tgttctatgg ggcgcttact tacttacaat aaattcagat
     2341 agaaacagct gaataaaaaa aggctccctg acccttagtt ggcgctaaga atcagggaat
     2401 gaccagtcac acacatacac cctgaccgat cattttgcca tagtcaatgc agtgcatcga
     2461 cctaatttat tgtacctaat ctagggtgaa aattctaccc ctatgtagat attttccatg
     2521 gtctgcacgt tgttttattt gctatgtcaa ggtattgggc gtattcgttc aatgcctttt
     2581 ttgtgtttga aacagcaaag accacatgtg ttactgtcta actactgttt ttttatgtac
     2641 ttccttagat taggcagctg tttctattca tgtcaagtat agctaggcgg gagagataaa
     2701 tgagtttatg ttattttgac tattatcacc aattggaaga gaaattaagg atagaagagc
     2761 cgctgatgct tcaagctggc acttggatcg cgaaacaaat taatcaaggt ggtagattgc
     2821 agatatatgc tagccgcaca ctaagtggtg tagcatttga attttgggat caaaccccgg
     2881 atcttgtacc aagtatattg attgaaaatc cagccggagg tgtctatgaa acgctagaag
     2941 gtgcaggaca ggcaattatt gatcagcttt ctgtcaaatc agaagacatt tttcttcttc
     3001 tttcgaatga aggaagaaac ccggcaatca tcgaactagc tcagtggatc aaagaaaatg
     3061 gtcatccatt aatcattgtt actggatttg atttgtcacg aagtatcaaa tcgcaacata
     3121 gcagtggttt gcgattattt gaatttgctg atttggtttt ggacaaccac gccaatttac
     3181 atgatgcagt cttgactttg ccaaatctag atccagcgat ctgcggaaca gcctctcttg
     3241 caacgatctt tttgctgcag caagttttgt attttacagc aaaacagcta gtccaggaca
     3301 caagtggaaa atagttatcc acatgttgac aaagttcctt aaaaaaataa tgttccacat
     3361 aaaaatggag cgtttgaaaa aaagaaaacg attattaatg aggattaaca acgactactt
     3421 tttttgtttt agttatttta agatggatca tctttgattt taagcttgtt ttgtttaaag
     3481 tttgttattt ttataagttg tttcacagtt atgagaaatg agttataaga atatgtagtg
     3541 tcagaaaaat aaaaagtagt ggaaaaagag acaagaaaga atccatatgg attctttctt
     3601 gtctcttaat acacgttgat gaaagagtct tccccaaaac tctttacaaa gtaattatag
     3661 tacatttgtt atcattattg caatgaagtt tacctgatat aacaaaattg tccaacagga
     3721 tacctttttc taatagaaat aaaatacaca aaaattgaag gatagataat ggatatttat
     3781 aagtgtttat tatttttttt gcaatgaaat tcaatttttc aatgattgta aaatgaaaaa
     3841 aacaggacga gattttctct aatctaaaaa taaaaaaaga attttaagga aaaacagaga
     3901 aataaaatac ttaatataaa tggaaagaga aaaaaataat catacatagg agaaaaaaaa
     3961 caaaatagaa aaaagtgatt ttctaataaa ttattcatgt ggaaatgtca tttttactgt
     4021 ataattcatt tgattatcca ttttttattc atcaaaatta ctgaaaaaag aaaggaagaa
     4081 ataaatttga agaaaacaaa ttcttcagga aaaccgaaac gcgacttcac taaattatcg
     4141 acaccccata cgtatgtcat tatttttggt gtagtcatct ttgcatggat actgactttt
     4201 gtcgttccag caggaaagtt cagcacgcaa gatattgaat acaaagatgc aaatggcgaa
     4261 acaagtactc gtactgtttt acgtcaagat tccttccgtt atgcttacga gctggataag
     4321 tcgtatgtgt ttgatcaatt agaagaactg caagatcatc cagcagaacg tgaaaaactg
     4381 gatgttccgg aaaaaggatt ggaaaaagtc attgctgacg gagaaaaaaa tcttacgcag
     4441 gaaaaactag atgaaatctc cttgacagat gatgtgcttt acgatcagta cggcgaaaat
     4501 atctatgata cttctaaaaa attgcataaa acagccaaaa tatggggaac agatgatttt
     4561 ggcggctttg gtttcttaaa ttttgttttt gaaggactag tatctggaga taagtatgga
     4621 tctgctgtag ggatcgctgc attgatcctt gttgttggag gtgcttttgg tattattatg
     4681 cgtaccggag cgatcgacgc aggtatctat gcgtttatca gtaaaactaa gggactggag
     4741 cgtttagctt taccgctatt attctttgct ttttcattcg gtggcgctac attcgggatg
     4801 gcagaagagg taattccatt ctcaatggtg atggttccat ttgtcattgc gttaggatat
     4861 gactcgatcg tagcagtaac cgtgacttat gtcgcatctc aagtcggaaa tgcgacctct
     4921 tggatgagcc cgtttagcgt agcggtggct caagggattg ctggaatccc cgtgttgtct
     4981 ggtgcgacat tccgattgat tatgtgggta gttgttactg cattagccgc tggttatatg
     5041 atgatatatg cagaaaaaat ccgtaaaaaa ccagaaagtt cgttgactta caaatcagat
     5101 gattatttcc gttctcatat caaaaagaca tctgatgaaa ataaaaaatt catgcttggg
     5161 cataaattga tcttattaga gatgttagtt gtccttgtct ggatcgtttg gggcgtgact
     5221 caaaaaggct attacattcc agaaatcgct tctcaattct ttgtgatggg attagttgct
     5281 ggaatcattg ctgttctttt caaattagat ggaatgaaag tcaatgacat cgcttcttct
     5341 ttccaatctg gtgcagctga tttagctggt acagcaatcg tagtaggtat ggccaaaggg
     5401 attcttcttg tcttgggagg atctgatgca tctgttcctt cagctttgaa tacgattttg
     5461 catgggatcg ggacggcgtt gaccggtgtt ccagctgtca ttggtgcttg ggcgatgtac
     5521 atcttccaaa gtttgttcaa cttggttgtt acatcaaatt caggacaagc agctttgact
     5581 atgccaatca tggctccact ggcagattta gtaggtgtat ccagacaagt agcagttctt
     5641 gcttatcagc ttggttcagg ttttatggac gcttttacac ccgtatcagc cagcttgatt
     5701 ggtgtgctag gtgttgcacg gatcgaatgg gcaaaatggg caagattcca aatcaagatg
     5761 caaggattcc tgtttgtttt aggaactatt ttcatcatga ttgccattgc aataggtctg
     5821 cagtagtact ggagacctgt aaataaaaaa gtaatccaaa cagtagataa ggactccaag
     5881 aaccgtcatt ttacggtaaa atcaaaggag taaagatcct atcgtttgga ttatttttta
     5941 agatcctatc atcagttata cttaaagaaa gaggaaaaat gtatgaaaat cattcgacaa
     6001 attgaagtgt ttgcaccaga ttacttagga aaaatggatg tactgattgc cggtgggaag
     6061 attttggctg tagaagaaca gctagaaggc ggctacgaag gagtggaagt agaagaactt
     6121 tcaggtgagg gaaaagtact aaccccgggt ttcattgact gtcatttcca tattttaggt
     6181 ggaggaggag aaggcggtta tcaaaatcga acgccagaag tcacattgag ccaattgact
     6241 acagctggtg taacgacagt tgtcggttgt ttgggaacag acggagaagg tagagatatg
     6301 actgcgttga tcagcaaagc gaaaggtctg gaagcagaag gaatctccac ttatgtatac
     6361 gaaggttcgt accgattgcc ggtaaaaaca gtaacagatt ctatcatcaa agactttttg
     6421 acaattgata aaattatcgg aatcggagaa atcgcagtat ccgatcaccg ttcttctcag
     6481 ccaagttttg aagagttcgc tcgtgcagta gcagatgctc gtgtaggagg catgttatcc
     6541 ggaaaagctg ggatcatcaa tgtccactta ggcggaggaa aaagaaagct agagctattg
     6601 acacgaatcg tagaagaaac agaaattccg atcacacaat ttttgcctac tcatgcaaat
     6661 cgcacaccag aattatttga agcttgcgtg gcatttgcca aacgtggtgg cacgattgac
     6721 ttcactgcta gcgaagatcc tgatttttgg gagaagacag atggtgaagt tcgcttcagc
     6781 aaagcactga aacgattgat cgaggaagat gtttctttag ataatttcac gatgacctca
     6841 gatggacaag gaagcttgcc ttattttgat gaaaacaatc atttcctagg gttaggagta
     6901 ggaagtgcca aggcattgct agtagggatc aaagaagctg tgcaaaaaga aagtatccct
     6961 ttggaaatcg ccttacgagc tataaccagt aatccagcac gtatattgaa attggataaa
     7021 aaaggaaaaa tcgaaattgg tgctgatgca gatctgtgta tcttggataa agaaacgctt
     7081 gatattgata cagttatcgc taaaggagaa ataatggtcc aagaaaaaga agtcaaagta
     7141 tgggggactt tcgaaaaaag tttttaatca acagctctaa ctatcttttt tagaaaacga
     7201 gcgttctgtt tgtctgtatc tgttgttgat gttaccctga aggtagatca ataaacaaac
     7261 taagaggagg aagcacaatg gcagatttaa aaggacgttc taaagatatg aaagataaag
     7321 tagtcggtga aggaaaagaa gcatacggca aagcaacaga cgacaagagc aaagaaacag
     7381 aagggaaagc acaatcacta ggtgctgaca tcaaagaaaa agctcgaaat ttaggcgacg
     7441 aagtcaaaga caagttttct cgaaaagacg aaaaaaaata aaaaccactt attactaatt
     7501 gaatcaagca aataaaaaat ccgaaccata tctgcgagac agatatggtt cggatttttt
     7561 atttgatcat tatcctgttt tttaaacttc gattttttga aattttttat tttttagttc
     7621 aaagacttca tcacagcttt ttgctacttc aatctcatga gtcacgatga taatacagcg
     7681 attttgttca tgggcgattt cttggaaaag tttgacgata tcttgtgaag ttgtttcatc
     7741 tagatttcca gtaggctcat ccgctacgat tagttgatgt tcacagcaga tagcacgaac
     7801 gatagcgact cgctgctgct gacctcccga aagtttggtc acctgttttt ttgctaatat
     7861 ttcatcaatt cctacacgag ccagtcgatc taaagcaact tgtcgataat tctcttgctt
     7921 ggtcttagtg atttccattg ctgctatgac gttgtctaga gccgataaat aaggaagcaa
     7981 gttgtaagct tggaaaataa tcgagacatc atttttacga taacttctta acccgatttt
     8041 gttcagtgaa cgatcttgat agtatacctt tccttctttt ggtgcatcta gtccagaaat
     8101 aagcgaaaga aaagtcgttt ttccagaacc acttgctcct aaaatagcgt acatttttcc
     8161 agcttcgaaa ttcagttcta catctttata aagcgcatct tgcggatctt gataccaaaa
     8221 tcccaattgt tctgtccgta acatcaaatt cctcctttag tttaatagga tttttcttgg
     8281 gtttaatctt aatatcccta tagaagctaa aaagacagaa aacagactga ttccaaatgc
     8341 tactccggct aatagtccca attgtgcagg tttgacattg atttccaatt cgctgacttg
     8401 atcagaaaca gcaaatggat tattcgtggt tccttgttga ccatcgcgtt gaccgccttg
     8461 ttcttgtctg ttacctggca tttgtccacc gccaggagct tgctggtttt gtgtcgtggt
     8521 ttctgtctgt tggtcaagta gctgctgtcc cacggcattc gcgacgacgt ttccgctaag
     8581 cgaagcaact cctaatgcaa gaatcataca aatagccact tcggtaaaca attggagaat
     8641 gattttactt ctggattctc ctaaagatag caagacgcct aactcatgcc gacgctcccg
     8701 aatggtaatc ataatgatca gagtaagtat gataataccg gctacagcca ctagtaaaac
     8761 aacattttta gaaaaacttg ccacgttgtt taaaggttcc aacattgact gatacatgga
     8821 atcatttgat tgtaagctaa atgtatctgt gtcgatcagc ttctcagctt ctttgagaaa
     8881 ctcatccatt ttatctggat cagatagagt gtaaatagca gaatctatcg tgttatcgtc
     8941 agatgtccca tttagttcat ttgcaaaagt gtaagaagtg taaagtgtat tcgacggatt
     9001 catgaagttg aatttcatac ccatactgcc gcttgtttcg ctggattcat aaattccttt
     9061 gatcgtcatt tcataagtgg tatcttcatc ttcagtactc gtgattgtga aagtatctcc
     9121 gactgccagg tcatttgttt ctgctagagt agaatcaatg actacattgt ttgtgccttt
     9181 gtcgctgtca tctattcctt caccatccgt gatttttgct gttccatcag aaaaattact
     9241 attttgtgca gttgctgaca caccactgat ttgaaagtct gcttgagtca tttgcggatt
     9301 cccgcccatt cctccagcag gttcaccgcc tgcatcagta gtttctgaac tgtcttcact
     9361 tgaatcagaa ctagtgatgg cagttattcc atcttttgcc atagctgagg cggaactttc
     9421 aaaggaataa ctctttaaat tatctaattc agctattttt tccgcgtccg ttaaggaaac
     9481 tggtgtaaga gaaaaactgc ctggatctgg acgttcttca gtggtagaac cgcttgaaga
     9541 agtttgttcc tgttttttaa atgaagcttc tcgattggca cttaaagtca ctgttgctcc
     9601 aacttctttt tgtgcttgat tcgctgcttc ttctgcagcg cttcgaatcg tgaggccagc
     9661 tagcacaaaa ataagaatgg ctgtgaacac ggcaaacaat aacaatgaac gtccccattt
     9721 tacttttgta cttttccatg cacgtttcat aaaattcata ttttgcatcc ctcctagtag
     9781 atgcatttga taatagacaa cctatcttaa agctagctta aatcttatgc tgtttgcaca
     9841 ccatcaacat gaggttctgt atatataaaa agtcactata gttattgcaa aaaatgtggt
     9901 aaaatgaaaa aagtatgttt caaaccgacg aagaagaaat gaaagaggaa tagcaaaaga
     9961 aatcctagat gctacagagg gatttttacg tgcatagttg ttctaacaat tgctgatact
    10021 agcgatttag tttatttgtt gtataataat ggggaacagc tgaatactta tataagtatt
    10081 ctggctatag cgtttcgcaa aagatccatt ttgttaatga agtatatcca aaataaaatg
    10141 cccatccaac tgtcagaacg cggatgtgct ggtaattttc ctgctgattc tccataagtt
    10201 gagaaatagt gattttgcat atgcttcatt ggaatggctc atatatttag ataaagaaga
    10261 aaatcgacat ctttaaactt ggatgtcata agaagaggtg aagtttgtga gtaccattaa
    10321 aattatccca ttaggcggcg ttcgtgaaaa tggaaaaaac atgtatgtcg cagaagtggg
    10381 cgaggatatt tttattttag attgtgggct aaaatatcct gaaaatgagt tgttggggat
    10441 cgacgtcgta atccctgatt ttacgtattt agaagaaaac attgatcgtg tagctggtgt
    10501 ctttttaaca catggacatg cagatgcgat cggggcactt ccttacttgt tgtcaaaaat
    10561 ttctgtacca gtattcggga cagagttgac gatcgagtta gcaaaattga atgtcagtcg
    10621 taatgaagca gccaaaggat ttaaggattt ccatgtggta gatgagcata cagaaataga
    10681 ctttggtgaa acagtagtga gctttttccg taccactcat acgataccag attcagtggg
    10741 gatcaatctg aaaacaaaag aaggtagtat cgtttatacg ggagatttta aatttgacca
    10801 aacggctatc ccaatgtatc aaacagatta tgcacgattg gcggaaatcg gcaaagaagg
    10861 agtcttagcc ttactaagtg aatcggcaaa tgcagaaaat cctcagcctg tagcttctga
    10921 agcccaaata gcagatgaag tatttgatac gatcaaatat tgggaagggc gtatcatcgt
    10981 cgcttgtgta gcaagtaatt tgcaacgagt gcaacaagta ttggatgcag cagaaaaagc
    11041 acaacgaaaa gttgtcttga ctggtcaaga tttcgaacga attattcgca cagcgatgcg
    11101 tttagaaaaa cttcaattac caagtgaaga tctgcttgtt acgttgaaag acatgaaaaa
    11161 ctatgatcca gaagaactga tcattttaga aactggccga atgggtgaac ccatcaagtc
    11221 tctgcaaaaa atggcaaacg gtacacaccg taatgtcaag attgaagaag gagatttggt
    11281 ttatatcact actacgccaa gcatcgcgat ggaaaccatc gtggcgaaaa cggaagatat
    11341 catttatcga gctggtggaa cagtgaagtt gatctctgag aatatgcgcg tttctggcca
    11401 tgccaatcct aatgacttgc aattaatgat caatttgatg aaaccaacat attttgtgcc
    11461 agttcaagga gagtatcgtg aattagctgc tcatgcagat ttggctcatg cagtagggat
    11521 gccatacaaa aatatctata ttactggacg cggagacgtg ctggaatata agaacaagcg
    11581 tatgagtgtt gcaggaacta caagtgcaga aaatgtaatg attgatggat taggcatagg
    11641 tgatatcgga aacattgttt tacgtgatcg aaaaatcttg tcagaagacg ggattttcgt
    11701 agcggttgtc actatcagtc ggcgagaaaa gaaaatcatt tcaaaacctc aaattacttc
    11761 acggggattc gtttacgtaa aagctagccg tgatctgatg aaagaaagca gcaatatgat
    11821 tgaaacaatc gttgagaaac atttagaaag caatgatttt gagtggagca aattaaagca
    11881 agacatccga gatcaattag gccgttactt atttgaacaa acaaaacgcc gcccagtgat
    11941 cttgccagtc attatggaag ctactcaacg tcgaaataaa aaataaacaa aaagagtaag
    12001 atgaacctct ctatagagtg ctcgtcttgc tctttttttg cgaaaaacaa ataa
//
LOCUS       DAFBSV010000085        11998 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.086, whole genome shotgun sequence.
ACCESSION   DAFBSV010000085 DAFBSV010000000
VERSION     DAFBSV010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11998
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.086"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            283..522
                     /locus_tag="LLB18_002273"
     CDS             283..522
                     /locus_tag="LLB18_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245257.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(884..1144)
                     /locus_tag="LLB18_002274"
     CDS             complement(884..1144)
                     /locus_tag="LLB18_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245258.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1329..1826)
                     /locus_tag="LLB18_002275"
     CDS             complement(1329..1826)
                     /locus_tag="LLB18_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HBK5245259.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(1956..2666)
                     /gene="budA"
                     /locus_tag="LLB18_002276"
     CDS             complement(1956..2666)
                     /gene="budA"
                     /locus_tag="LLB18_002276"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HBK5245260.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="LLB18_002277"
     CDS             complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="LLB18_002277"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HBK5245261.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(4548..5210)
                     /locus_tag="LLB18_002278"
     CDS             complement(4548..5210)
                     /locus_tag="LLB18_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBK5245262.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            complement(5220..6035)
                     /locus_tag="LLB18_002279"
     CDS             complement(5220..6035)
                     /locus_tag="LLB18_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBK5245263.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(6297..6740)
                     /locus_tag="LLB18_002280"
     CDS             complement(6297..6740)
                     /locus_tag="LLB18_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HBK5245264.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(6874..7212)
                     /locus_tag="LLB18_002281"
     CDS             complement(6874..7212)
                     /locus_tag="LLB18_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK5245265.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(7200..7577)
                     /locus_tag="LLB18_002282"
     CDS             complement(7200..7577)
                     /locus_tag="LLB18_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBK5245266.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            7801..8994
                     /locus_tag="LLB18_002283"
     CDS             7801..8994
                     /locus_tag="LLB18_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5245267.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(9160..9582)
                     /locus_tag="LLB18_002284"
     CDS             complement(9160..9582)
                     /locus_tag="LLB18_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5245268.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            10172..10627
                     /locus_tag="LLB18_002285"
     CDS             10172..10627
                     /locus_tag="LLB18_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245269.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQAAAEQASQQAQAAAP
                     EQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSKCYGN"
     gene            complement(10789..11961)
                     /locus_tag="LLB18_002286"
     CDS             complement(10789..11961)
                     /locus_tag="LLB18_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBK5245270.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
BASE COUNT         3640 a         2383 c         1989 g         3986 t
ORIGIN      
        1 ctatcctcct agcaactatt taaataccca aaaaaattac ctctagataa tatcatacct
       61 acgttttcac ttataaattt tttcataaaa aaagcgttta gaggcataat cgttaataca
      121 gatggtaacc aatgtatctg gtttgaactg ggatatcacc ctctccatat atgtattact
      181 aagactaata gatactataa aagacttgat agttttgcat tgattttgcc taatactgag
      241 cataggtgta tgctaaacga tactataagg agtgtgtaca taatgaaaag aattctgttt
      301 atcagtttat caaatttatt gttacttact gcttgtggga cttctgcatc aaagaacata
      361 ccttcagata cgcaaatttc gaatagtatc gattcaacaa tttctacaaa tgagaaaaat
      421 tctccggtag aaacttccga tataaaagtt tctacctctg caaaaaacag ggtaaagaaa
      481 ctgtcagcac gtctccttta tttcaaacaa actctgaatt agcttcttca tcttcttcag
      541 caaataatga tgatagtttc gcgtttactc ctaactaaat gcaaccttta caaatgcttt
      601 acgataacaa gcctgagcta aatgatcctg atatcagttt tgcatttttt gaaatgattg
      661 gatcggatga tctttttaaa actactagtt tgtctatccg aaaataggac agttctggca
      721 gtataggttt ttatcgagtt tctccaccag gcctcgttac agagacagat tctctaggcg
      781 aaccttttga ataaatcaaa aatcatgaac aatcactgcc aactaaataa agtgccttca
      841 aaagcttggt cttctcgctt ttgaaggcac tttatttaaa tctttatgaa actaaagtat
      901 gttcatattt gttgctatag ttatatagat attctgttgt ttccaactca taaacgtgag
      961 tatattttgc cactactttt ccgcattttt ctaatatttc attgcgatcg acgtcatgat
     1021 attcgtctac gcagatcaca acacaatttt ctaatttact gattacttct ccaaccactt
     1081 tttgtttcaa gccaataggt tggcaaatat atttttttcc taaaatgata gtttcgttat
     1141 tcatatttca tccatcctta atgtttttcc attatttaaa atgataatac cattaaaata
     1201 tgattatgaa aatcaataac acttgtgatt ttataaaaaa ataaaaaaac cgaaaaacag
     1261 aaatgcccac tgtctttccg gctcttttta ttcttgattt ctcttctttt ttgtttcaat
     1321 agacgatttt agttattaat aaatgaaaaa gcatttatat taaaatttgc taataaaaga
     1381 tctacatatt tttctagaaa tgcttgatcg atttcatcat accctttcgt tactccgcaa
     1441 tcgatatcta aaacaccgat taaattacct tcttttacca ttggcactac gatttctgat
     1501 tgtgcggctg aatcgcagga aatgtaattt gcatgggttt tgacatcatc aacgatcaat
     1561 gtttcttgtt tttcagctga ttctccacaa actccttttc ccatcttgat acgtgtgcaa
     1621 gaaactcgcc cttggaacgg tcctaaaatc aattcattac catcgaataa ataatatcct
     1681 gcaaagacag tctcaggcaa agtctcattc aacaatgcag atgaatttgc taaatttgct
     1741 aaccagttat cttctgcttc taataatcct tgttgctgta ataataaaat ttcgtatgca
     1801 tcttttttct gtttttctgt ccacatgata aaaaccgctc ctttttgatc tatggagaag
     1861 attatagctc agtttttttg taaacgctag gtttcctcct caaaaaaacg agatacgtca
     1921 ggttaatcac cttgaacgca tctcgctgtc tttttctatt ctgcttgttg gatttctgct
     1981 gctaaatcag cataatcaat cgtttcgtga acaaaagtcg gatcatcaac tggaaaatgc
     2041 tgtacaaggg acgagatgcg gctaatctca acttttcctt cagccacttc aaaatccatt
     2101 acatgtccgc caaatgtatg tgtatcatcg ataaaatgca agtgaaatcc cgctgcagca
     2161 actccttgga ataattcagg cgtaaagaac ccgactaatg ttccttggac attgctttgt
     2221 tggaattctg gttgagactc tgaaattttt gctagtcttc tgtaaggttt ttcttgcttc
     2281 ggcatgatac ggatgtgcat atttttgaat aatccagtta tcttcactgc caaaaatagg
     2341 ttttccccgg cttctcttac taatatgtct tttttcaatt gttctccatc tgcagttttt
     2401 gagacagaaa aactagtatc tggcgtaaaa tctgtaattg ctgcataggg ggtaagttca
     2461 cttccatcta attgggcaac tgagccatct gatcttcctt gataagctac gccatctaaa
     2521 aagatgactt caccatcaag cccatgcaat gttcccaatc ccagagttcc tttttctaat
     2581 atatgagcaa tcgtttctgt tccatccatc aagccagcca tcaaagctcc taatgtcccg
     2641 tgctggtata agattttttc agtcatgtcg acacttcctt aatagaattg atctggtaag
     2701 attgtttctc ccaatttctc attatcacgg taatcaatcg gaatatcaat aattacgggt
     2761 ccttctgtcg caaatccttc ttctaaagct ttttctaatt cctctacact tgtagctcgg
     2821 attcctttag cgccaaaagc ttctgcatat ttcacaaaat caactggacc aaagtctaca
     2881 cctgacgccc gctgatattt cattttttct tggaactcta ccatattgta gtgtccatca
     2941 ttccaaatca aatgaacgat attcaatttt ttacgtaccg ccgtttctaa atcctgggca
     3001 gagaataaaa atcccccatc gccggaaact gatacgattt gtgtatttgg acgcaccaat
     3061 gcagcagaaa tcgcccatgg caatgcaaca ccaagcgttt gcataccatt actgaataac
     3121 aaatgacgag gttcataact tctaaagtgg cgtgccatcc aaatataatg actacctaca
     3181 tctacggtaa cagtcatatc atctgttact tttgactgaa gcgtgttaat aacttctaaa
     3241 ggatgcaaga tacctgcttc tccttttgat tgaacaatgt cccgctccgt taattctgct
     3301 tgaagagatg ctaaatattc ttttgcatct tctgacactt gttgaggctc taatgaacct
     3361 gtcaataaat caagagtggc tgagatatca ccgatcaatt ctctttcagg ctgcataaaa
     3421 ggatcgattt cagctggcgc ttcatcgatc acaatgatcc gcgcatcttt ttccgcattc
     3481 cagtttcttg cttcatattc gattggatca tagccaatag caataactag atcacttcgt
     3541 ttcaaaagca tatctcctgg ttggtttcta aataaaccca cacgaccaaa gaaatgcgct
     3601 tctaattcac gtgagatcac tccagctgct tggaatgtct ctacaacagg caatgctgtc
     3661 tttccaacta attgcctgat ggctaacgtt tctttttcac ttgatcctcg catacctact
     3721 aatagtaccg gtagttttgc ttctctaatg cgttcagcta ggtaacggat atcatctgca
     3781 gaagcagaac ctaatttagg atcgctcaat ggcttgatga cattcccttg gacaggtgca
     3841 tccactacat cttgcgggat actgataaag ctcgcgcctt tttttgaact cttagccata
     3901 cgataagcat tggcaatcac ttctgaaatt gtttctggat cttggatttc tgcactgtat
     3961 tttgtgattg gctggaacag tgctgcatta tccatgcttt gatgggtcaa cttcaataga
     4021 tcgcttcgtt ttacttgtcc ggcaattgct aaaactgggt caccttctgc tgtcgctgtt
     4081 accaaacctg tagctaagtt actagcacca ggaccacttg ttgcgataac tactcctggc
     4141 tctcctgtaa tacgtccgat tgcttgtgcc ataaatgcag cattttgttc gtgacgagtc
     4201 acgattaatt caggaccttg atcctctaat tcattaaata caccatcgat ttttgcacct
     4261 ggtataccga atacataatc aacatgatga ttaatcaaac tttctactac agatttcgaa
     4321 ccttgtttca ttttttcgtc cattgaacat cgtccttttt atgctttatt tttaattatt
     4381 agttagaaat aatcacaaat aattgataca gtttctaaac ctgtttcatt caaaagtata
     4441 gcacgtttta tttcatttgt ttagccatat gtttcaaaaa atgaaaaaga atgacagttt
     4501 ttacataaaa actgtcattc ttaattgaaa gtttcaattt ataaagtcta cagatccata
     4561 gttctcatca atttacgatt gttgaagtaa atcaaaccaa atacgataga aggacctagt
     4621 agaatacacc attggggctt tacgaaaaag aagagaaaca aacttgtcaa tagtaaaaaa
     4681 tctagtaaac tcacatacca ttttttcaac gtatagtaga acgctatccg tagaacttga
     4741 tttggtttcg acgctggatt tctcacctga aaataccagt agttgatgct aaaggaaact
     4801 gataaacaag caagtaaaac aaacaacgga atcaaccatt ttccataaga aaaacgtata
     4861 aaaaagaaac aatcaaaaat cattatcaca ctaactatcc aagcaaatag ccaataaaaa
     4921 aatcccttta gccaaaattg gcgaaacgtc tttatgaaca aacgtactgg tgaaaaactt
     4981 ttttcttttg ctaattcttc tgtcatacct atcatcacga tgcaacctgg accaataaaa
     5041 agtaaagaaa aaataaagga aaagacattc cttccatcta tcgacaaaag gaacgcagct
     5101 gctatataca agatattgac acaccaaaaa caaaggctac ttgccaatga ttgatacaac
     5161 caataaaaga attccatata aacatttttg tcaaaacgct gctctttcat aatcacctcc
     5221 tattccttca ttcctgatga agcgatccct tctacaaaat atttttgcat cgctaaaaat
     5281 ataaaagcaa caggaagaac agaaacaact gaggcagcca tgattaatgc gtactctgca
     5341 tcaaatagcc caataaacat tttcaaccct aactggattg ttttattttc cgtagaagac
     5401 aaataaatga atggccccat ataatcgttc catgtattaa cgaatgtgat gatcgtcaaa
     5461 ctggcaatcg ccggttttgt aagaggtaaa atgatcttgc gatagattcc ccactctgat
     5521 aagccatcga tccgcgcact ctcacataaa gaatctggga tactactgta gtattgcttc
     5581 aacaagaaca caccaaaagc attgaacgct tgtaatagca ccaacgacca caacgtatat
     5641 gttaaaccca cttttctcat cataatgaac tgcgggatca tataagactg ccaagggaca
     5701 gcaatcgtgc cgatatatgc taaaaataaa atatcgcgcc ctttaaaatt tagtttagaa
     5761 aacccgtaag cagcaaaact agaagtaaac aactgaatca acgtgatcac aacgcttaaa
     5821 aaagctgtat tcttaaaaaa tgtcactaaa ggaatacgag accaaataac cagataattc
     5881 tctaaatgcc aagttttagg gatccattga atcggaatcg tgaacacttc attatttgct
     5941 ttgaatgaag cagaaaccat ccataaaaaa ggaatgatcg tcaataaagc taatacaatc
     6001 agcagaatca tacccaacca ttgaataaag ggcatgtttt ttgaacgaat ttttgctttt
     6061 tttctttcat ttcgaacacc tccaaagtta taatcttcat ttctttgtaa tgattacaat
     6121 ccagaacaac ggttattata gctgattcat ttccgttctt cttatgtttg taagcgctta
     6181 tttaacaagt tatgtaaatc tctttatttt ttttgattta aaaatgaaaa aatacaaaag
     6241 caagactgtc atacgtctcg cttttgtatt gaaatttctt cgattagaga tacttattac
     6301 tgttcaaaag cttctttgaa acggtgaatc aattcattga ctacaggtga taaaatccga
     6361 ttctttttcc agactagcat gcagttcgtt tcaatcattg ggtcaagcgg aacgaatgtc
     6421 actcgctttg aaagatgact tacagcacct tctatgacta aagcagcacc tacctgattc
     6481 tcaattagcg caaatacatt gaaaatcaaa ttgtacgttc ctgtgatcag caactgctcc
     6541 ttttttatgc ctaaccagtc agcaaacatt cgctgtattt ctggacgctt tgagatcaaa
     6601 agaggtacat tcgcaaagtc ttcttttgtt atcacgtctt tttttgctaa aacagaattt
     6661 tctaaaatga gcaatcccca tttttccttt cttggtaaca aaatcgtttc gtatttctct
     6721 gtatctactg gatctagcaa aatcgctaaa tctaacaggc ttttttctag tcactccgtg
     6781 atatcatcac ttgttccgct gtggatatga aattgaacgc tgggataatc acggatcaac
     6841 ttttctagta atagtgccaa tgtattcgaa ttatcagctt ccacacagcc gatcgtaaat
     6901 cggccgctga ataattgttt ttttctgttc tcgaattctt gagtggtttg attcgttaaa
     6961 tctaaaattt cttctgctcg gcttttttag aaaataacct gcttctgtca agatcatttt
     7021 gcggttttcg cgtacaaaca gttctgttcc tagttcctct tctaactcct tcagttgtcg
     7081 gcttaaggtt ggttgtgtaa gatgtagaac ttctgcggct tgagagattg ttccttcttc
     7141 tgcaattgtc caaaaatatt ttagtaagcg taactccata gcgatgctcc ttgatttttt
     7201 tacttgatac attccatttt atttctagat aacacacgat catatttctt gatttttcct
     7261 tgtaaacgtt ccaaacattc ttgcatttca gcaatttttt tcgtcaaaag ttcactttct
     7321 tcaatcaaaa gcttacgccg ctcaaataca gttgcttctc cttcgctaga taggcgaata
     7381 tattcaatca aagactcgat cgataatccg gcatttcgca tacagatcgt aaagtcgacc
     7441 cattttaggt cttcttctgt ataatcacgg attccgcctt ttgtccgatt aactggtgga
     7501 atcaacccga ttcgttcata atagcgcaat gtatcggccg aaatgccctt ttcttcactg
     7561 acttgtttga tattcatctg atcactcttt ctcttaattt cttgccactt tacttatgta
     7621 ttttatttat tctacaactt taagtgtact ccaagtcaat actcatttct attaaaacta
     7681 agctggatta tctatatcgg ttgtttgtgt attatttcaa ataaaaaagt cttgtttttt
     7741 tattcttttt tggatatact tttaacaatt tagggaaatt ttaggaaaag gggtataaaa
     7801 atgacaacgt atcagcgaaa gttattatta tcgacatcgg cgggaattgc tttagagaat
     7861 atggatatta tgtttttagc tttttcatta tcttcaatga ttacttcttt tcatattagt
     7921 ggtacgcaag cgggtttcat ttcaacgatc actaatttgg ggatgctcat tggaggtatt
     7981 ttttttggca tcatagctga taaatatgga cgtgtgaaag tattttctca aacggtcctt
     8041 ctgttttcga ttgcttcttt attgatgtat tttgcttcaa acatctactt ggtttatctc
     8101 tttcgcttta tcgcaggtgt aggagcggga ggagaatacg gggcgtgtat gtccttgatt
     8161 tccgaaagtt tttcaaaaaa acaaattgga cgagcttctt cggttgctgg tattggtgcg
     8221 caggtcggtg cggctttggc tgcgatttta gctgctgtga tcattccaac gtttggttgg
     8281 aagatgttgt atgtcgtagg tgtactgccg gtgttgatgg tcttgttcat tcgtcgcggc
     8341 ttgactgaac caaaggaatt caaatctgta caatctgccg aaaagaaaac caaacttagc
     8401 agactgtttg aatcaaaaca tcttgcttgg caaacatgtg gccttagtat catggtaact
     8461 gtccaaattg ccggctattt tgggttaatg aattggctgc cttcaattat gcaaaatcga
     8521 ttagggcttt cggtttctgg gtcttcattg tggatggtca gtactatttt aggcatgtct
     8581 ttggggatga tgacttttgg cataatcatg gataaattgg ggcctaaact agccttttct
     8641 ttgtttttaa tttgttcatc cttatctgtc tatctacttg tgttagccca tagccagtgg
     8701 agtttggtag cagccgctgt gatagtcggc tactttatca atggcatgta tggtggatat
     8761 ggcgcagtga ttagtagttt gtatccaaca gaaatccgcg cgacggcgaa taatttcatt
     8821 atgaaccttg gacgagctgt tggtggtttt tcttctatcg tcatcggttt cttgatggat
     8881 cattatagtt taactgccgt aatcttgttt ttgagcggta tttacctagt cagtctgctg
     8941 gtcttgacaa ctcttactgg tgttacagca ttaagggaaa gcttgcagca ttgatagttg
     9001 agtctgtaaa tgacaagaaa gaggtgtggc aaaagcttgc atctgcggta ataagaccag
     9061 ccaaatcaaa aacatgagac actgtttccg tttggctggt cgtattactt gatgcagggc
     9121 agctttttca actgctaatt tccttctatc tggcggctac tattctttga cgtccgtcat
     9181 ttcaaagtac tttactaata acttagcata acgaaaaact gtggatacac tcgtatattg
     9241 agcgtctgca taatcttcca aatttttctc aggatgttga tacatgaatt caatcaaatg
     9301 ataattatat gattttctgt agaaatgaag ataaataatg tagattggga agttctcctg
     9361 cttttccata gaaaagcgcc gattattctc attcttcaaa atgaccttat caggatattt
     9421 ttggaacaat tcttctaaat ctgttagata attcaagata gacttacttg ataccttcaa
     9481 ttcgttttgt agttcttcta ttgaacacca acgttctgtt tcaagcagta aatgaatcat
     9541 tttaattttc ttttgagaaa cttttgttaa aaaagtctgc atattttctc ctcctgtatc
     9601 tactttacta tactacatac aagaaaaaaa acggatacaa atatcatatt gtcacaccgt
     9661 caatagtgca taaacctgtt attatttctc tttttttcct aagtattcta ttgatatgaa
     9721 tcatttaatc gtttattata taaatgtcaa taatctaata ataaaataac gtacatattt
     9781 tattattgca tacttaataa cagaactata gcaaaaaatc ccgtgtatca aaacgggatt
     9841 agattaagtt tcctcaatca ctattcataa cacaattatt ataacaagta agtaaacaat
     9901 tgaaaaggac atttattgaa aacggttgtt ttttacttaa ggaggaaatt tagtgaaaaa
     9961 attagttgca ttgtttttgg tcgcaggaag tttgttgagt gggtgtggtg ctactacgtc
    10021 tactactcaa agcacaagtt cagctcaggc ttccagcagc agtaccacga tctccgaaag
    10081 tacggcagat tcatcgaaag aacaagaaca aattgaaaag aaaaaagaag aagagaaaca
    10141 aaaagcggaa aaagctgcac tagaaaaaaa agtgacagaa gcggaatctg ctttgtcaca
    10201 agctgaagca aatcctacaa aagaaaacta tgcaactgct tcagcagcta tccaagcgct
    10261 acctgaaaac aaacaagagt tgacaagccg tcttgctgca attgattcca caatcaaagc
    10321 aaaagaagca gaagaagaac ggaaaaagca agaagaaatt gcacgacaac aagcagaaca
    10381 agcgcaacaa gaagcaatcg cacagcaaca agcagaacag gcgcgacagc aagcagcagc
    10441 tgaacaggcc tctcagcagg cacaagccgc agctcctgag caaaataatg aacaaactgt
    10501 ctatgtcaca ccgaccggtt caaaatacca tacacataaa tgtggaaatg gtacgtatac
    10561 ccctgccact ttaagcgaag ctcaagctcg tggtttaacc ccttgctcca aatgttatgg
    10621 aaactaattc aaaagttata ctataataat aaaattcttc tgaaacataa aaaaatagaa
    10681 gctggcgttc cagatagtaa accaaaaata gcagtttaca cgtccatttc gtcagcttct
    10741 ctcttttttc atttagtctg ttccctctgc ttttttggac atcttcattc attctttctc
    10801 aatcaaatag tacacctctt tttcttttcg cagtttatat cttccttttt tcaatttcat
    10861 tgaaaactgt ttcgaatgtt tatgttttac atggatttta agcaggagct cctcatgttg
    10921 caagcgatag ttcctgcctt ttaaatcaga aaatctcact agtccgtatt catcagaagc
    10981 tttcacaaat ggaacttttt ctctagtaat atagtgtttg ccgttgagcg tttttacaga
    11041 aaagaccatt ccttcgattg gtcgtccgtt tgtgttcttt acataaaaag ataaaggata
    11101 gtttcgctta gcgatggcca aagaatctaa ataagcgatg agtagccaaa ctaagccgat
    11161 tgatccaagt agtataccga taaaccaaat aaaaaatttc cattttttcc attgatcaat
    11221 tccttggatc gctttttttg cctcttttgc ttgataagga atacgatgcc ccgtcacaag
    11281 cagtcgatgt gtattgacca tataaggagt acaggtaagc aaagtcacga gatctctgcc
    11341 tttttggata cccaaagaat ctacttcatc aggtaagacc acttggattt tttctacttg
    11401 atacgccaat gtctttccat tgatctggat gaaaaactgg tctccttttt tcaacttagg
    11461 caaatctgta aataattttg cttctgggag tccacgatgc ccagaaagaa cggcatgggt
    11521 gtttttcccg ccagtcggat aagaactttc ttccaataat gacgttcctt tttgcaaaaa
    11581 tatttccgtt gtctgatcga atataggtaa gctgacattg atttttggga tttcgatgac
    11641 tccaagcata tgttccataa aaaaggcatt actaggtaaa tcttttaatg cttttgcatc
    11701 aactgcttgg ttgaaactgc ctatccctgg tgatacgttt tgctctgcca actgttggtt
    11761 tttctttgtc attttttcct gctgtttttt tatttcctct gaattcttat tcgatgcttg
    11821 cttttgataa tggatgatca tttgctgggc aagaaaatca ttcagtgaat cttctacaaa
    11881 aggataagaa aagatcccga tcccaacgac taaaatgatt gccatgaaga tgtccagtat
    11941 tcttattctg cttttattca tcatgtccac ctattttcta atatgtatat gaagaggt
//
LOCUS       DAFBSV010000086        11510 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.087, whole genome shotgun sequence.
ACCESSION   DAFBSV010000086 DAFBSV010000000
VERSION     DAFBSV010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11510
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.087"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(79..2154)
                     /locus_tag="LLB18_002287"
     CDS             complement(79..2154)
                     /locus_tag="LLB18_002287"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBK5245271.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDIKTDRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKDHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEV
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(2156..3073)
                     /gene="glyQ"
                     /locus_tag="LLB18_002288"
     CDS             complement(2156..3073)
                     /gene="glyQ"
                     /locus_tag="LLB18_002288"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBK5245272.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRF
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARSVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            complement(3457..4269)
                     /gene="recO"
                     /locus_tag="LLB18_002289"
     CDS             complement(3457..4269)
                     /gene="recO"
                     /locus_tag="LLB18_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBK5245273.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFLSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHAYPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKMPEKNMPEKEIPEKEE"
     gene            complement(4412..5311)
                     /gene="era"
                     /locus_tag="LLB18_002290"
     CDS             complement(4412..5311)
                     /gene="era"
                     /locus_tag="LLB18_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBK5245274.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYTALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(5326..5721)
                     /locus_tag="LLB18_002291"
     CDS             complement(5326..5721)
                     /locus_tag="LLB18_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HBK5245275.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQIDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            complement(5705..6181)
                     /gene="ybeY"
                     /locus_tag="LLB18_002292"
     CDS             complement(5705..6181)
                     /gene="ybeY"
                     /locus_tag="LLB18_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBK5245276.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(6198..8390)
                     /locus_tag="LLB18_002293"
     CDS             complement(6198..8390)
                     /locus_tag="LLB18_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBK5245277.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVVFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNTGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            complement(8414..9385)
                     /locus_tag="LLB18_002294"
     CDS             complement(8414..9385)
                     /locus_tag="LLB18_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBK5245278.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            10090..11469
                     /gene="brnQ"
                     /locus_tag="LLB18_002295"
     CDS             10090..11469
                     /gene="brnQ"
                     /locus_tag="LLB18_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBK5245279.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHYVPFAALGLGWVVPTLLGYAGSLLFYYVYRVSGYK
                     QEASELPEE"
BASE COUNT         3106 a         2419 c         2105 g         3880 t
ORIGIN      
        1 ttatttatat ttataacaaa taaaccagag aaatagccta ttttgtgcct gttctctggt
       61 ttatttacat attagaaatt attttgtgat gatttgatct aaacttgcta gtgacaaagc
      121 catggcagca atttgactta attgcgttaa tcggttctta cgtactgctg gttcttctgc
      181 catgaccatc gtctgatcaa aataattttc gatcagtggg cgaaggctta caagctgatc
      241 ataattttcg ttgatcgttt ggtcagcaaa gcttgttttc attacctcta ctgctttgtg
      301 cagttctttc tccgcttcgt tttcgaacag ttcagggtct acttctgatt gtttttcaag
      361 ctccgctttt ttcgctaagt tcacgacacg tgtcaaagct tccatcgatg gtttgaagtc
      421 ttcatctgca agatgctgct tgaacaattg tgctgctgca aatacttttg tcagatcttt
      481 ttgttctgcg ttcaaaacag cttcgatgac atcatgacgg atattcttcg ttgtcaataa
      541 ttggcgcaga cggcctttga taaagtcgat cacctgttgt tgtcccgctg acaagccaat
      601 gccaaaacga tccgtatctt tactgataac ttcactaatc gtttcttgca gaacagacaa
      661 aggaaaggcc cattttttcg attcgatgat tcgaacgaca ccatatgctt gacggcgcaa
      721 agcatatgga tcgtttgagc cacttgggat catcccaact gcaaagaaag aaaagatact
      781 atctaattta tcagcaatcg ctaaaacaga acctactgta gtctcaggta aatctccttc
      841 actggatata ggcatgtaat gttcacggat cgctgttgct acggctggtt tctcgccttt
      901 aagcagagca tatttttctc ccatgatccc ttgtagttca gggaattctc ctaccatgtt
      961 ggttactaga tcaaatttat agatttcagc agcgcgttgc agatccatca attcttcctc
     1021 agacagtcct acttgttcgc ctatgatgcg agcgatgact tgtacccgtt gcattttctc
     1081 atagatgcta ccgatttttt catggaaagt aacagttttt aatttttcaa cgtattggtc
     1141 gattgaagct ttcttgtctt cattataaaa gaattccgca tcttctaaac gagcagtcaa
     1201 tactttttga ttgcctcgta ccacattttc caattttacc cgatcgccat tacgagcaga
     1261 aataaaatga ggaagcaaca taccttgatc gttccgtact tcgaaataac gttgatgttc
     1321 tttcatagaa gtgactagta cttcttcagg aacagataga tatttttctt cgaagtcgcc
     1381 agaaaagaca gttggatatt cgactagatt gttgacttct tctagtaaat cttcatctag
     1441 atcaatgatc cagtgatctt tttctgctaa ttcgtttgct tgtgtgatga tcatttcttt
     1501 tcttttttgc ggtgaagcaa taacaaattg ttcatttaat ttttcttcgt attcttttgc
     1561 atgcgcaaat gtcacatctt cgcctaagaa acgatgacct cttgaagctc tgtctgtttt
     1621 gatatccaag atctcaaacg ggattacttc gtcatctaac aatgccacga tccagtgaat
     1681 aggacggata tattcaaaat cgtattctgc ccaatgcatc gttactggga aagtgaggct
     1741 tttaatgaca tctgctaaac ctgtcaatac ttcttttgct tctttgccgt gagtgtattt
     1801 cgttacatag acatattcca cgccttttaa ttctctaaaa gtgatagcat ctgtcgtcag
     1861 accttgtccg cggacaaatc cttccgctgc tttcgtccag tttccatctg cgtccaaagc
     1921 aatttttttg gctggtcctt tgacttcttc ttcactgtct gcttgacgtt ctggaatgtt
     1981 tgttactttg attgctaaac ggcgcggtgt agaaaatgtt tcaatcgtat cataagtcaa
     2041 ttggttttca tctaaaaatt ttgctgtttt ttcttctaat tgtttcatgc ttggtgtgac
     2101 aacatgagca ggcatttctt ccagcccaat ttcaagtaat aagtcttttg ccatcttatt
     2161 cagcctcctt cacgttttct ggatttgctg tgtttttatt caataaaggg aatcctaatt
     2221 tttcgcgttc tgccacaaag attttggcta cagaacgagc catgttgcgg atacgggaaa
     2281 gataacctgc acgctccgtt acggatactg caccgcgggc atctaataaa ttgaatgtat
     2341 ggctgcattt caaaatataa tcatacgctg gatgaacaag attttcatcg atacagcgtt
     2401 tagcttcttt ttcaaaacga tcaaagttgc ttagtagcaa gtcttggtcg cttacttcaa
     2461 aagaatattt ggaatgttca tattctggtt gtttgaagat ctcgccatat ttcacgccat
     2521 cagcccattc taagtcatag acactttcaa cttcttgaat atatgaagca agacgttcta
     2581 gtccataagt aatctcagaa gtaactggtt tacaaggtag tcctccgact tgctggaagt
     2641 acgtgaattg tgtaatctcc atcccatcaa gccatacttc ccaacccaca ccggcacaac
     2701 ccatcgatgg gttctcccag ttgtcttcaa caaaacgaat atcgtgttct aatggatcaa
     2761 ttcctaaaaa acgcaagctt tctaaataaa gctcttggat attttcaggt gaaggtttca
     2821 ttacgacttg aaattgatga tgctgataca aacggtttgg gttttctcca taacgcccgt
     2881 cagctggtcg gcgggatggc tctacataag cagcattcca tggttccggt ccgattgccc
     2941 gtaagaatgt atatgggctc atcgtacctg ctcctttttc tgtatcataa gcttgcatca
     3001 gcatgcagcc gtttgatgac caaaattttt gtaatgttaa aatcatatct tggacggtca
     3061 attttttact catctgtttt gcccctttca atttttaagc gttgctgtca ataagaatac
     3121 aggaaagaaa acgacaaaaa gtccctatgt ctgattacag acatagggac gaataatttc
     3181 gcggttccac cctacttccg aataaagatt cggcagcttc atttatcgta ctcgcaagtg
     3241 cctcttcaaa aatcgtttgg gtccggcttc cactctcccg aactcgctaa accacgtgtt
     3301 ttttactgat cttggtcaat gtacgtattc attttgcagt tttcttgttt atataataga
     3361 tcctctcagt gaacgatcta tttaatctac ggttaataat agacggaagt ccctgtattt
     3421 gtcaaatagt tttgattttt ttgttgtatc tttcatttat tcttcttttt caggtatctc
     3481 tttttcaggc atatttttct ctggcatctt taatacgtgt gcccaagact tcatttgatc
     3541 aatgaacttt ttgcttttta gatgaatacc gacatattca tcatacaact ggtcaatgag
     3601 gtcacggatt gcctgcttcg tttcttcttt caagtggatt ccactgatct tatcataaga
     3661 aatagccgaa aacattcgaa cgaaataaac agcgcgagga tatgcatgat aacggtgttc
     3721 gtccattggc cagtgtttct cgcatatcac gccgccatat ttggaagaat agtcaaattt
     3781 tccttttgtt tccccgcata cgacacagtg cgtccaaatt ggcgcgattc cgaagcgttg
     3841 cagtatttga acttcaaaga tattcgtgat gatttctgca tcatctcctt ggtccatccg
     3901 ctgcagagct tgttgcgtaa attggaataa gtgcgggtca tattgatgat cttcgattgc
     3961 tgcatctact agatttagca aatacgtacc ataaccgctc aaaaagatat cttcttggat
     4021 gttccgaaac gcatggacgt ctttgacact gcttaaaaac gacaaacctt cacttagaaa
     4081 attaccgata tagactgctt cggtaaaggg gagcaaagcc ggagctaatg gctgattttg
     4141 ccgatggatt cctttgatat aaaacatcat tttgccagaa gattccgtaa agattttgac
     4201 taatttatct ttttctttgt aattacggct agataaaatc aagcctttcg attctgcaag
     4261 ctggctcata ttctccctcc taaaaaataa atctggaaaa gcagattctg ccgatccaga
     4321 ttatttatgt tacgatcttt cgctgttttt ctcaacgtac ggatttttat ccagtttatt
     4381 tctataccta acctataaga agtccagaat atcagtactc gtcttttcgg tagccgaagt
     4441 cttgcagata gacttttttg tctcgccagt ctttttggac tttgacccaa agttctagaa
     4501 atactttgtc tcctaaaaga ttttcgatat cctttcttgc tttcgttcct acttgcttca
     4561 gcatttttcc acctttgccg ataatgattc ctttttggct atctctttca acgatgatcg
     4621 tggcctggat atggatttta tcattctcgt ttcgcttcat cgaatcaaca acgactgcga
     4681 cagaatgagg cacttcgtct cgtgttaaaa acaagacttt ctcacggatc aattcagaaa
     4741 cgatgaagta ttcaggatga tcagtcactt gatcatctgg aaaatattgt gggccctctg
     4801 gcatttcact gactaataca tccattaagc gttcgacatt gtttccttct gtagcagaga
     4861 tcggaatcac ttgtgcaaaa ggcatctgcg tcgaataatc ttcgatgatt cccagcaact
     4921 cgtctggatg gatcttatcg attttattga taatcagata aactggagaa tgcacgtttt
     4981 ttagacgttc aataataaaa tcgtctcccc ggccgcgttt ttgatcagca ctgatcataa
     5041 ataagactgc atccacttct ttcaacgcag tgtaagctgc ttctaccata aaatctccta
     5101 gacgatgctt tggtttatgg attcctggtg tatcgataaa aatcagctga gcttctggtg
     5161 tagtatatac tccttggatt ttatttctag ttgtctgtgc cttgtcactc ataatggcaa
     5221 ttttttgacc cacgattcgg ttcaataatg tggattttcc tacattcggg cggccgacga
     5281 ttgcgacaaa ccctgattta tgttctggca tatacgttct cctttttaat taaacaacaa
     5341 atgatatatt ttagggacaa ataaaatcaa cccaatgatg acagcaaaac aagcggtcac
     5401 taaaactgct ccagctgcca tatctttgat ttttttccca atcggatgaa aatgaaaatc
     5461 cgtaaacatg tccactacat tttcaaaaac agtattgatg atctctacta tccaaacgag
     5521 aaaaacagct aaaagcagcc ataaccactc tatccgatca atctggaaaa tcacgcccat
     5581 aaataaagca aggataccga acgcaacatg tttcctcata ttgcgttctt cctcaaaaac
     5641 ggttttgact ccttggacag caaattccac ggacatcagg aaatgtttgt ttttctctac
     5701 gtttttatct tttgagtcca taggcatcca agatctcttt ctgtaaacca aacatttctt
     5761 tctcatcttc tggtgtcata tggtcatacc cgttgatatg caagaatcca tgtaccgcta
     5821 aaaagccaag ttcccgatca tatgaatggc cgtaagcttc tgcttgttca gcagcacgtt
     5881 caatagagat catgatgtct cctagtacac gaggcaatgg attctctcca tcttcaaaaa
     5941 tcactgggat ttcgtcttcg ccttcttctt ccagagcaaa actgatgacg tctgtcggtg
     6001 catcttttcc acggtaatca cgattgatta cttggattgc cgcattgtcc atgaaagtaa
     6061 cagacatttc tgtttcctct ggcagcttta aataagatgc tgcaaattgc agcaagtcat
     6121 cgatttcttt cattttctct tctgagactt ggtttgtttc atccataaag gtaatatcca
     6181 ttatacatcg cttctttcta ttcttcttgt tcttccttta tcttctcaac ttctgttttc
     6241 attttaggat atttgatccg agaatggaag gtgctactta aaccgctgat caatgatttt
     6301 tccacttttc ggatttcttt caaggtcaat ccactatcgt ctaattgacc atcggaaata
     6361 cgctcttcga taagattatg gacaaaactt tcgatttttt cgctcgttgg atgatccatt
     6421 gcccgtactg cagcctcaca actgtcagca atattgacga tccctgcttc acgactttgc
     6481 ggttttggtc caggataacg gaattgctct tctgttactt ccggattgcg ttctttcgct
     6541 ttgatgtaga aataacgcat tagcgtggtt ccatgatgct gtttgcaaat atcgatcacc
     6601 atttgcggca tattataatc ttccaatatt ttggctccat ctgtcacatg tccaaagata
     6661 atatgtttac tgtcttctgg caataagaaa ttgtgcgggt tttccgctcc tgaaggcaag
     6721 ttctcaacga aaaagctagc gtgtttgatc ttgccgatat catgataata gcaagctact
     6781 cgagttagta aagaacgtcc gccgatttct gctacagcgt tagcacttag attagctacc
     6841 atcatactat gatgatacgt acctggcgct tcttccagca actgtttcaa taaaggatga
     6901 tttggattgc tgagttcatt taatacaatt acactgtcat cattgaccat caattcaata
     6961 tatgggtgta gaccgatcgt cagcaagaat gagaagagtg caccagtgaa cccgcagaca
     7021 agcattaacc aagtcgttgc atcaccaaag ctcattcctt gatagacgat caaaatgaca
     7081 tccatcatca caggaaaaat aatgacccac atggcagcag ataatccttg ttctgagatc
     7141 cgtttacgtc tgacaatcgt tgccatgagc ccagagaaaa cataagacat caagataatc
     7201 gttagaaagt tcgtgccaat cgaatcataa aaaatgaaaa gtgcggatac tgcttggaaa
     7261 ataccagcca tgatccctgc tcttcgattc aagaaaaagc ttaaaacaag tggtgcaaaa
     7321 gcagcgggat aaaacagcgg gatataagta gcttgttccg tttggaataa ttggaaaaat
     7381 ttcatcagca ctatgctgac tgacatagct gtcacataga aaagaacgta ttttgttctt
     7441 tctcctgtat tttggaattg aagtgaatta taaatcagta cgccgatttg aagcaaaaca
     7501 gctaaaacca tggcaattag cggaaaaatc gaagttgttt gattagtcag tcctagtaat
     7561 tccaattttt tcatagctga agcatcaatt tgattacctt cacgaacaat gatttctcct
     7621 tggaagatca tcactggttg tacagcttct cgtgcggatt gtttcaattc ttctgtcttt
     7681 ttctcattca atacgtcatt cactacgata ccttgatcca ctaagtagcg aatcatttgt
     7741 tgttgtgctg gtgtgacatt caaatattgg atttgctctt ctgcttcttg tttaaaagct
     7801 tccaattcac tttcacgaac ttgtttgctc atctgttcgt caatgagctt cagactctca
     7861 tccctcacag tatgaatctc agtttcagtc atttcaaata tcgtcgaata aaaattgttc
     7921 ggtagttttt gataaaacac aacattttct gcattcacat tttcaaaatt tttcttcagc
     7981 gcggcgatcc gctcttctgt agtaggcttt gggatatttt catcttcctt tgccttatca
     8041 atcttttcgt cataagattt gttgatggca tcattcgtct tatcgatcaa ttcaaatagt
     8101 tgcttgatcc gattgttctg gtcatctgca agatcttttt ggtaagtgta ttctggagtg
     8161 actgcttctg ctgccagttt tcttttttgt tcggtttctt ccgtgttctc gatcgttttg
     8221 ttcgcacgga tactttcttc tgctacttgg ccttctctga aatcattggc cttttgtttg
     8281 acactactaa atgtaacgcc gcagataatg ataaaaaaca agaacagcag gaaaggcaat
     8341 gctgcctttc caagtttttc ttgtagtttc tgcagtgttt tattcaacat gtgcttatcc
     8401 tcctaagcaa agcttattct tgatggagat ctgccttttc ataagctttg atgatttcgg
     8461 caactacagg gtgccgaaca acgtcacttg cttcaaaatt aacaaaatcg attttcttga
     8521 tttgctttaa tgttcgttct gcatgaacaa gaccacttgt tgtccctcga ggcagatcaa
     8581 tctgactcgt atctccattg acaatcattt ttgattgata accaagacgt gtcaggaaca
     8641 ttttcatctg agcaactgtc gtgttctgtg cttcatccaa aataacgaat gcatcatcca
     8701 atgtccgccc ccgcatgtaa gctaaaggag caatttcgat cacgcctcgt tccatcaatc
     8761 ggttcgtatg atctaatcca aaaatttggt ataaagcatc ataaacagga cgcagataag
     8821 gatctacttt ttcttttaga tccccgggaa gaaagcctag attttcccct gcttccacag
     8881 caggccgcgt caaaatgatt ttttgcactt cacctttttt caaggcagcg attgctaata
     8941 ctactgcaag aaaagttttt cctgtcccgg ctggtcctac gccaaatacg atatcatgtt
     9001 tggctaccga ttcgacatat ttcttttggc cgctgttttt tacccgtata ggttttccat
     9061 tacggtcttt gacgatctct tcctcataca tctcaacaaa ataatctaat gtgccttttt
     9121 gccccatttt cagtgccgtc acgacatctg gtgtacttac atggattcct cgtttgatca
     9181 attcctgcaa tgtccgaatg actgaggcag ccaaggaaat ctgggattgt tcgccaatga
     9241 tctgaatgat ttctccacgt gtatggatgg ttgtttctgt tgtttcttca atcagtttta
     9301 tgtgcttgtc gtgtgcacct aaaagcatgc tgacatcatc agcagccgtc aatctaatct
     9361 ctaaagaact agactcttcc gtcaaaaata gacatcccct ttttttcgat tcattctttc
     9421 ctattttacc atactcagaa gaaactatat agcaaataag aaaaggttct aaaagagttg
     9481 cttaaccata agtaccaaga aacgttaaaa aatagctgct tccattctct aaaggtctcg
     9541 tttgaataaa aaaagctgat catgtaagct atgcataaga tagaggacaa gtattccgtc
     9601 taacttagca agtattctct gggtattttt cttgtttcaa aaaaagaaaa caaaatattt
     9661 gaaatattct tgcatttcaa aaaaaacagg tgtattataa cgtcaacaaa taaatataca
     9721 gcaaagcgtc gaggaaaaca gtaggctatt cagtgattta ttcccagtga gtcatgtaag
     9781 tgagaaatga caataaatcg aatagacgaa catcatttcc gagtcaatgt cgaaaacgta
     9841 gatcattgtg gctgcctcca ttatcaggcc agcggataac tttatcgaaa agcgtccgtg
     9901 aatgaagaag cttttttaag cgaaaaaagg tggtaccgtt ctagaatcta gagccctttt
     9961 cccaagtgga aaagggcttt ttttatattt taaggtggtg gttttcatgg aatctgatat
    10021 tagtggtatt tctagtttct gcaacgttta ttttgttact caaaatgata attattggag
    10081 gaaaaattta tggaagaaac aaaaacttat tcatggaagc aattattgat ggtcagttca
    10141 cttatcttcg ggatgttctt cgggtcaggt aatctgatct ttcctgtcca cttaggtcaa
    10201 atggctggat caaactggat cagcgctggt gtaggatttg ccatctcagg cgctcttttc
    10261 ccattattag ctatcttagc tgtagtagtg acaaaaagtg atggtctgta tgacttagct
    10321 aaacctgtcg gaaaatggta tgctgccttg ttcttgatcc ttgttcattt aacgatcgga
    10381 ccattctttg gtacaccgcg gacagcagca actgcttttg aaatggctgc taaacccttt
    10441 ttgcctgaaa aatatgattc attaggtatg tttttattct ctgctctttt ctttttactt
    10501 gcttatttcc ttactgtaca tccaacacgt ttggtcaaat atgtcggaaa gtatttaaac
    10561 tccttgtttc ttgcattatt agctatcatt tttgtcgttt ctttattcca acccatgggg
    10621 aatctaaacc aatctgctgc agattcttat cagacgaacg ctttgacaaa tggcgtttta
    10681 gaaggataca acacggttga tgcagtagct ttacttgctt taagtgtcac ttttgtccat
    10741 gcagttcgtg atcttggttt taaagataaa aaagtcacag aattaacagc aaaagctggt
    10801 agcctgagcg ttgcgttaga agtcatgatt tattttggtc tggtccttct cggtgcgatg
    10861 agtttgaata agatgtcttt atcagaaaat ggcggaactg cactttctca gatcactaat
    10921 ttttatttag gtaacttcgg tgctagcttc ttaggggtaa tggtcacatt aggtgtcttc
    10981 actaccgcta tgggactcgt tgtttctttt gcacaagatt tccataaact gttccctaaa
    11041 gtcagttata tgacatggct gcggttaacg acttttgtct cttttgtcgt tgcgaatgcc
    11101 ggattggata atatcatcca atggtcttta ccagtattga tgcttttgta tccattgtca
    11161 cttgcgttaa tcttgctttc cttaacagca aaattcttcc aaaagagtcc atttgtctat
    11221 caagtaacga tgttcttttc tgccgttcca gccgtattgg atatgttggc aaattcgcct
    11281 gcattagtga gtcagcaaac tgtcgtagca agcttactag gattttatca tcattatgtt
    11341 ccttttgctg cattaggact tggctgggtc gtcccaacgt tgcttggtta cgctggcagc
    11401 ttgctctttt attatgtata tcgcgtatca ggatataaac aagaagcaag tgagttacca
    11461 gaagaataac caaatcaaac acaatttaac ataagagata ttaaacagga
//
LOCUS       DAFBSV010000087        11253 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.088, whole genome shotgun sequence.
ACCESSION   DAFBSV010000087 DAFBSV010000000
VERSION     DAFBSV010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11253
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.088"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="LLB18_002296"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="LLB18_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBK5245280.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="LLB18_002297"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="LLB18_002297"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBK5245281.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="LLB18_002298"
     CDS             complement(2169..2906)
                     /locus_tag="LLB18_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBK5245282.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="LLB18_002299"
     CDS             complement(2997..3524)
                     /locus_tag="LLB18_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245283.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="LLB18_002300"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="LLB18_002300"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBK5245284.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="LLB18_002301"
     CDS             complement(4401..4886)
                     /locus_tag="LLB18_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBK5245285.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="LLB18_002302"
     CDS             complement(5039..5236)
                     /locus_tag="LLB18_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245286.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="LLB18_002303"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="LLB18_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HBK5245287.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="LLB18_002304"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="LLB18_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HBK5245288.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="LLB18_002305"
     CDS             9211..9423
                     /locus_tag="LLB18_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HBK5245289.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="LLB18_002306"
     CDS             9425..11104
                     /locus_tag="LLB18_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBK5245290.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
BASE COUNT         3265 a         2429 c         1971 g         3588 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tcatacaaaa aaa
//
LOCUS       DAFBSV010000088        11228 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.089, whole genome shotgun sequence.
ACCESSION   DAFBSV010000088 DAFBSV010000000
VERSION     DAFBSV010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11228
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.089"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(<1..2327)
                     /gene="esp"
                     /locus_tag="LLB18_002307"
     CDS             complement(<1..2327)
                     /gene="esp"
                     /locus_tag="LLB18_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HBK5245291.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
     gene            complement(2944..3378)
                     /locus_tag="LLB18_002308"
     CDS             complement(2944..3378)
                     /locus_tag="LLB18_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245292.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(3395..4600)
                     /locus_tag="LLB18_002309"
     CDS             complement(3395..4600)
                     /locus_tag="LLB18_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HBK5245293.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            5294..5680
                     /locus_tag="LLB18_002310"
     CDS             5294..5680
                     /locus_tag="LLB18_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK5245294.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            5774..5965
                     /locus_tag="LLB18_002311"
     CDS             5774..5965
                     /locus_tag="LLB18_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5245295.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            6479..6811
                     /locus_tag="LLB18_002312"
     CDS             6479..6811
                     /locus_tag="LLB18_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK5245296.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            7107..7262
                     /locus_tag="LLB18_002313"
     CDS             7107..7262
                     /locus_tag="LLB18_002313"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBK5245297.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            7538..8878
                     /locus_tag="LLB18_002314"
                     /pseudo
     CDS             7538..8878
                     /locus_tag="LLB18_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9119..10735)
                     /locus_tag="LLB18_002315"
     CDS             complement(9119..10735)
                     /locus_tag="LLB18_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBK5245298.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            10853..11071
                     /locus_tag="LLB18_002316"
     CDS             10853..11071
                     /locus_tag="LLB18_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5245299.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
BASE COUNT         3677 a         2084 c         1689 g         3778 t
ORIGIN      
        1 cctgcggtga aggttacttt gtggtagcct gcaggaatgt tttctcctgg attttcataa
       61 atatctttac ttacagttac tgctaaatcg gtcgtgccta cagaaccatc ttggtaaaca
      121 attttaatag gaattgttcc agtaatcggc tccgattctc ctacaccttt agctggagtg
      181 aatgtaacaa taccagtgtt tgcatcaaca cttgcattac cgaagtcctt attatagaca
      241 tctgaaattg aaaaggcatc tttagctaaa ggaacatctg gtttatcaaa tgtaggtttt
      301 ccactttgaa ctgtcgtttc tggagttgtt gttataggta cgtatgttgc atcattttcc
      361 atagcttgag aagcttttac agcaaactct acatccacgt cgaaagttcg atttccgatc
      421 ttaacagtta caataccttt cgtactatca gtaacgttag aagtatcagg ctctgttttc
      481 catgaatact ctgcatcttc aggtaagttt ttattattcc gaattgattc tttagcatct
      541 ggtttaaatc caactaccac ggtttgttta tcaaccgctt ttggtgattc cttaataacg
      601 gttgaacctt cttctggttt atcaaaacct ggagaaacga tttggatttt taattcatct
      661 ttcgcgatta atttacttga atctacaccc gtaaattcaa attctacagt atctgaaatt
      721 ggagccccat ctttttcatt tggagcgata gttttttctg ctaatacagt accttcttta
      781 tcaacaagtt gggctttgtg acctgttccc gctaactcgt ggatgaatac tttcccctta
      841 actgttgtgt caacatcata tacttcttct aattcaggtt tcccgatata tggattcgtg
      901 tctccgctct cttctttatc gtcagggttt ccatcaccat caatatcttg caaataataa
      961 taacctgttc cataagtgtt ctggattaat tttttattcg tatccgacaa ccaagaatca
     1021 aagatgaaat cttcaccaaa tggtttattt tcttcaactt gtgctgttgc tttcatatct
     1081 tctaagattt catctaatgg cttagtcaat tgtaaaacat atcgaataac gactggacgt
     1141 ggacttgcat tagcaaaatc gataagttta gttaaatcat tattagttat tgaacctatg
     1201 ccataatttt catgaccttc ccgtcgctcg attgctaaat cagctacttt tgttccggat
     1261 tcaaacgaaa catcatatgt tactttgtca gcctgaacca tgtgcatctg tatacccgct
     1321 acatatggaa ctaatcgttc atcaattttg taattagcat accaaggcgt gccctttgcg
     1381 gaagatgaat atgagaaatt ataatttttc gttaacttat gatctaagat tatagctcca
     1441 ttagcacctg tggatcctga accatctttt gtttgagtat taggtttctc atattttgca
     1501 cttactgatc catgtttaaa ctggtcagga ttattttcag atacatctaa gctattatag
     1561 aaatcatctg aatctgttaa aaagtagccc gtactatcaa tacccggtac aattttatca
     1621 tcgtcttgat gacttaccaa gtagattcga tacattaaac gatcggtctt gagattgtct
     1681 atgcctatct ctttaaaaat ttcatctagg ctcttttcaa acgtaattac cccattagga
     1741 gcggtttgcg tatcggttgt ttctgcccca gcaaataatc catcacttgc acgaatataa
     1801 ttgaccttcc aaatatttgt aggtctaccc agcgaatcat taattcttac aaaggtccgt
     1861 ctagaagatc caattccttt ctttggatcg acctgaattt tttctacata tttagctaat
     1921 cgttcatcta attgaagacg gatttcccag tttttagttg atgctgcaat attatgtttt
     1981 ccgtaaactt caaatccaat tgtattgcct tttagtgtgt ctccagttag ttcttgagga
     2041 ctaaattgta aatccgaaaa gttataattt ttcgtataac caggattctc ctgaaaagta
     2101 ttccccgaag ctactttgtc acctacttgt acggagctta tcgctgtttc aagtgggctg
     2161 cttggagaaa tttcatcttg tgctttaact agttcagttg ttcccaagac aagaccaaca
     2221 ccaatcaaaa cagatgcaac cccaacactt aattttttga tactgtactt caatactcgt
     2281 ttctttgttt tttctagaaa tactctctta ttattcttgc taaccattat tcaaatcaac
     2341 tcccttaata attactttcc tagtaagaat aaaagataaa tctgatacgt attattcaca
     2401 gaataggaat cttactaacc ttatgttaac taatttactt agagaatttc atgaacatta
     2461 caacaaaaaa agtacatttc ttcatgtttt tttcggatat ttgtgctttt taaccattca
     2521 gcagctgaaa acatataaaa agatatgtat gtattctttc tgaaattaag ttcatttcta
     2581 tgcgatgaag catgttttca aaatattacc ctttcttaga ttaaacttca gagtattcaa
     2641 ataacggaat aaggagcctt atcccgcatt actgaatgag actgtgacat aagtaaaaag
     2701 gtgacttcaa attccttctt cggaatttga aatcaccttc tttataatta taaagtatcg
     2761 gtttcacagc atttctgaat gattcctaga atcttaaacg aatgattgga gttatcaaca
     2821 ttttttcact cgtttttagc gaaacaaaaa atgacatttg tcacagcctc attaaattat
     2881 tgattctttt tctttataat tgaattgtcc atatttaaag tgtctagtac tctacatgaa
     2941 taattaattg ctttcactca aatacttata atctattaac ttgtagttgt ttaacttttc
     3001 tgaaaaagtt agacccacgt aataatcttc ccagctttct ctttcaatta actgatccaa
     3061 tttttgataa tccataaatt catcatgtat caaaaagaat aaataacttg atattttagc
     3121 atctagctta atcagattaa ataatgtttg tttaaaattg ctaccattaa tatgactgat
     3181 agattctcta gcttcttcac ataaactttt tactttatta attactactt tgtcatattc
     3241 atttaacaca ctattattac cattacttag acgctcagat tctacgaaac aactcaaatc
     3301 agaaatttcc caaaaaaatt ttttgttaaa atccaatttc ctcaactcct ccaaactacg
     3361 taaatgatat agtctcataa taaaataaaa cctctcagct aatgttgttg aaattgtcca
     3421 ctaaacctaa ttgatattgc ttaggagata cacctgcgta ctttttgaat actctcgaaa
     3481 agtgtgaaga atctgaaaat cctaaaccta aagaaacttc actgatagta tggtttgatt
     3541 tcaacattat tttagccgta gaaatttttc gcttagagat ataattataa atcgtaatat
     3601 gcatttcatt cttaaagctt tctcttaatt tagtttcact tacagaaaaa taattagcta
     3661 tttcctttac agtaattctt ttatagatat ttaagccgat gaattgaacg acagaagaaa
     3721 ttaagggaga aagatgctct atcttagttt ttccgatttc cttagtataa taaacaatcc
     3781 cagaatccct cacttttaag acctcaggta acgatacagc taattcgttt tcttgtatca
     3841 aagcatctct actttgatac gcttctatta tatccattcc taatgttata gacgtttgtg
     3901 ctaacttttc aaaaacaatg atagaataat ttttttcaga ccgaatcgta tctccactaa
     3961 cacttggaat tattccatta ctcagattaa aaaccatgtt ttctaaattt cgaatatctc
     4021 catttttaac atattccagt attttatttt cataaagaaa cagatatatt tctggatcgt
     4081 aattttgtga taacagatta tctattttga tttgctcgat agttttactt agattttctg
     4141 tatattcaat taacggttca tggaatagat cttctatttt tccagtaaaa aaataatgaa
     4201 ctaaaatcag aatatctcga atgtctccta aagaatacaa agtcaaattt tgcaatgaat
     4261 tatagagtcg ttctctatca gccattgcaa cattcaaatt gttcattttt agtttaaaaa
     4321 aaactttatc aatattattt gctctaaatg gaccaaataa gtaatatctg gttttaaaca
     4381 tgtatagaag aaacatctca ttaaaatcac cagtaaagaa atggaaatct ttagtttttt
     4441 taatattatc agttagtaac tttttataat cataaaaaaa ataagtagtt ctatctgagc
     4501 gatactcttt tataatactg aattcggaat taaaaaccac gataggtaac tttaaacaaa
     4561 catgaagaga ctttaataag acttctttat ctgaaaacac ttttgtttct ctctttcctt
     4621 tctacatcat taaatagtat tttatacgtt atctaaaata ctattcctct gtcaaaataa
     4681 gctaacttac ttcattataa aatatccact tatcgctttc atgtatattc caccgtaaaa
     4741 agtacatttt atcaccgaga actcatcatt tttcatcatg atgaatacta tttacatata
     4801 tctagttcaa agacaataat tattatgatc cgttattatc taagcactat acagataata
     4861 ggaatttttc gtttctaaat attccaattt gggaatccaa taaaaatttt cgttcaaata
     4921 cgtgtctatt cgaactcttt tctagttgtt aattatgaag ggggaagaaa taaaaaatac
     4981 aatctataca cgaataagaa tattatccaa aaggaggttt tagaaaagat ttattatacg
     5041 taaaaagctc aagacatttt cttagccata aggacatgtt tgatatttaa gaagatatat
     5101 gaattttctt ttctaagtat aaagataact atccattatc aactaaaaaa acatttttga
     5161 aaataaacat cagcagtcct atcaatgcat gtgagcttat agaagttatt cgcagcgcag
     5221 cataattgca ttagcttctt ttcgtgtttt ttgcctcttt tccctttaaa tcttaatgga
     5281 ggaggtgtgc aatatgtcag ataacgacga acgcgtaaat gcccagttga ttcgattctt
     5341 tgaaaaggtc attttgaaca ccgctaatac ttattataaa aaacaagaag aaattcaaaa
     5401 acatgaacaa cttgatcaac tcccaccata tttgtttact aaagatacta taaaatttaa
     5461 acaaccgatt aatgttttaa atgtgactct ccttgttgaa gatataaaat tagcaaaaat
     5521 ccttcctttg ttgaaagaac ctgaacaaat ttttcttatc gaaaaattta tctttgataa
     5581 aactgataaa gaaattggaa aggttctggg gattacaaga cagggtgcga caaatttaaa
     5641 acatcgactt tacaaaaaaa ttcaaaaaat gctggtttaa tatctgcata ataactaatt
     5701 ttgtatgctt ctttgctcgt tctcctcctt cccaaagaaa tagattataa gtccatggga
     5761 agaaggtaga tttatgaatt ctttaaaaga agatttcatt ttagcaaagg ctggaaatga
     5821 agaagctgtt gaggcaattc tcaaaagatt tagctctttg attcataagc aatcctggag
     5881 aactggaaaa tatgatcaag attgttatca agaatgtatg cttgcaatat atctagctat
     5941 ctcgaaattc gaaattaaag aataactcaa ctaagggagt ctgtgacata agtaaaaaga
     6001 tagtttcaaa tttcgaacaa taaatttgaa actatcttct ttataattat aaagtatcga
     6061 ttttacagcg ttctataatg attcatagaa tctaaaacga atgattttaa ttatcaacgt
     6121 tttttaattc gtttttagct taaaaataac ttttgtcaca gtctcactcc taaaattact
     6181 ttatttacgt atgaagtggg caggaggtcg aatccagaac tgggctatgg tacttcaacg
     6241 aggacttctc ctctagaatt gaaaagcatg cgatttacct tccgtaacga cggtagattt
     6301 attcaactat gtgtccaatc aaaatttgtc tgatttcaaa aatagtcaag agaattttgg
     6361 ttgttaaaaa ctcttatcta tcaacttcca cagtttagtt gacaaaccct gatactaagt
     6421 tgggctatga tacacttttc ttgactatca gttacgttac cggaaggaat gaactctatt
     6481 gagaaaaaca tatgatcgta aatttaaact aaagatttca caggatatcc ttgagaaaaa
     6541 agtaactacc aagaaaattg ctgaagaata caatatctct cgtccaacaa tttcccgatg
     6601 ggtttcagaa tatcgtcgat acgggaaaaa tgcttttgct ggacaaggaa aaagattacc
     6661 tgataaagca gatttctaca ttcttgaaca ggaaaataaa cgactaaaag aggaagacga
     6721 gtgttctacg aacacaaaga tcgatacgga tctccaggga tcactcaaaa actttacgat
     6781 gaaggaatcg aaatcaataa acgtgttgta gctgttctta tgcgtgaaat gaatttatgc
     6841 acaagaggat ttcatcgacg caaatcttct catggtagag aaaaaacaat caaagaaatg
     6901 gtaaaaaaat gttgaatcga taatttgaac agaaccaaat tgatgctgtt tgggtgatgg
     6961 atattactta cattccatgt aatgacggtc gcctctattt gtccacctat attgacttag
     7021 caactcgtat tctacgttac tatatggtag attcacacat aaaaaaagag attgtcgtcc
     7081 gtccattaca aatttattaa ggagaattgc ctacggtaat tcattccgat agaggtagcc
     7141 agcatcggtc ttttatttat caagagctgt tgaacgacca ccacatcaca cattcagtga
     7201 gccaaactgg gactcctgtt gacaatgcag taattgaagc gtttcatcga tcaatcaaat
     7261 gagaattaat cgactccaac aaatataaaa gtaaaataga gatgaaggtg ttaatccaag
     7321 attatttaga agactactac ccaaacaaaa gaatccatac aaaatttatg atgactcctt
     7381 gacaatttga agcgaagaaa ataagggatc tataatatct agtgttggtg acgccttctg
     7441 ttgccaatac tttttctttt ttctaataaa cgcaaacaga caccttaaaa tcctttagaa
     7501 taaagtcgac aaaaaccatt caaagtagtg tttcaagatg tcctattcag agtttaccaa
     7561 agagttacta gatattctag acctaaatct tacctttcat gaggatgcct ttcgcaaaga
     7621 gcgcatcaat gacgaaacat gttttgcttt tgatggcaca ttgacctatc aaccggagga
     7681 atgctttcat cgccactatc aaaatgaaca aacgatcatt aaatagggct ggaaaaaagt
     7741 atccatctta ttgaatgatg tcagtaacta caagaccatt ctgcggatta acaaacagcg
     7801 cttcaaatgt aaacactgtg gaaagacttt tttagcagaa gattcagtta gtgatcgtcg
     7861 ctgctccatt gctcgcagag tcaaacaagc cattcttgag ctattaagcg aacctctttc
     7921 tatgtctttg atcgcacgta tgaagcacat ttctccgacc actgtcattc gaatacttcg
     7981 cagccttcgg cctaaaacca tttctttgag ccagctgtta ccagaagtgg tgtgtttcga
     8041 tgaattcaaa tcagtgaaaa atgtctcggg agccatgagc tttgtcatga tggacggcaa
     8101 gacccatcaa ctgattgata ttgtggaaaa tcggcaactc aatcctttac gcgactattt
     8161 cttgcgctac cctataaaag tccgtgaaca agtgcgtcta gtggtttcag atttctatac
     8221 accctatcgc acattggtga aagagtgttt tccgaatgcc cgaatcgtcg ccgatcgctt
     8281 tcatattagc caacacattg gtcgggcttt taccaaccac cgaattcaag taatgaagac
     8341 ctttaaaaaa ggggatcgtc ggtcgaagca cttaaagaaa tactggaaac tacttcaaaa
     8401 gaatgcgtgg gaattgaaag gtcagcatcg ctactggcgt ccgtcatttc gagatcatct
     8461 gacagaagca gagatagtcg atcggctatt atcttatgat gattccttaa agcgaggcta
     8521 cgaagtctac caggattttc tttccgttat cagaagacaa gatgttcctg aattcgtcgc
     8581 gctcctaaaa gaagactaca aggagttgcc agagcactac caaccagtgt tcacgacctt
     8641 caagaaatac caaacagaaa tcaaacgagc gttgcgcgtt ccctattcca acggccctat
     8701 agaatgtttg aataaccata tcaaagtact aaaacgaatt gcctatggct atagaaactt
     8761 tcaaaactac cgagaacgaa tctttttata tcgaggaaaa tattttaaga aaactaagaa
     8821 tactacccaa ctgactaaag ccagaacaac aacacggcta gacaagatag ctgtctagcc
     8881 gtgtgagtat ctcgattatt ctattgaatt tcttcaccaa cactcattga cgaagagcca
     8941 aaataagtaa tctaaccgac tgttaactaa accattgcag gtcccgttaa agatacttgt
     9001 gcctgttgtc accgcttctt tttcttgtcc acaagcgctt aacacactta ataaagcccc
     9061 tgctattatt aataataata tctttttctt attaaaaacc tcctcatcta tttccagatt
     9121 agtaaatgta gtaatctgtg ctttcttttt tctcaatact aataactaac ttatggggta
     9181 aacaaatact cgtttgaccg ggttttgaga tccatccagt tctaaccgcg atttgatcag
     9241 gactattatc ttctttaact cgaattcttc catctttaat ctcaacaata ttatattgtc
     9301 ccttcgcagg atgataattc acgagtttat gattgatctt atccaaatcg aagcgatcca
     9361 tttccttgcc atcaattcga acgatggcat atttgatagc atcttcagtt gtttcattct
     9421 ccttttctat agagaataca aataagggaa taaaagaggt aataatcaaa atgccaataa
     9481 ttatgacatc gcctatcttg acaccagctt ttcttaaaaa tttcattaac gatatctggc
     9541 taaacatatt agactttttc catggaaatg gtgaaatttt tcggaaatta tctgcattaa
     9601 gagaatcagt taaacaaccc tcaagttgtt ccttaataca ttgttgatcc atcttcatac
     9661 caataaaaac tagtttatta atgcgttcac caaacaacgg atgccaggct tccttcaatt
     9721 cgggattttt ttgtataatc atttgacact caattttagg taaactagct acccaataat
     9781 ttaatgattc aatactttta tagctacccg atgtttcaaa gatcgtcgaa aaatcactat
     9841 gttgggcaaa ccaaagaaac ccttttgctc ttgtaatatt gccaggaaaa tttttatccg
     9901 taagatgggc aaatttttgt gcgtcaagga gtaaccgatt tcgatagata aaacttgaga
     9961 taccatattc ttctgtttca ggaatatgat tttgatagcc aagctctaac tctttgaacc
    10021 agcccactga ataggaagtc tcatctatat taaaaagatt tgtatttaga attttcgata
    10081 agtctacttc acctttaatt gtcctaatta ttttggcatt ggactgtaac ttagcaatta
    10141 gaccgttaat tttgtaaatc gtcttggttg acactaagtc actattattt aaaagtaata
    10201 tgttacaaca ctcgaattga tcaattaaca agccacgaat atcctgttct tcttcaacta
    10261 cattaccttc agcttttctt tcctgaatct tttcacccgt ttcgaaatta tcccaaaaac
    10321 gttttacatc cactactata ataatggcac caatctctaa tcgttgggtc aaatcaatgt
    10381 ctaaagggtt tttagctaat ataattgctt gaataattgg aattggtttg ctgattcctg
    10441 aagcttcaat aacaatttga ttcaagtcag aaaattgcac taattgatct agttcaacaa
    10501 tcaaatcttc gcgtaatgta caacaaatgc atccattcgg catcgaaaca agtttttctc
    10561 cagttctttt aaaacctttc ttgtcgacta ataccccatc aacatttact tcccctatgt
    10621 catttacaat gacagcaatt tcctttccgt gatcaccgta cagaatatga tttagaagta
    10681 tcgtttttcc tgaaccaaga tagccagtta agattgtaat aggtattttt ttcataggga
    10741 acctctttct ataccttgaa tttacacttt aagtgcaaca cataaaaatg agtcataatc
    10801 gatatccaac tagtataagt ttgtcgagaa cactcctaga aggaaaataa ttatgagcca
    10861 gtatcgtcat cttactatac tcgaacgaga aagaatcttt ctgcttcacg aagaaggatt
    10921 ttctattagt ataattggca acgacattca gcatagcccg tttactattt tacatgaact
    10981 gagaagaaac aagaaaaaaa ctattcacct tccaaagcgg aaaaaaatta tgcttatcga
    11041 agaaaaaaat gcggacgtta tcacattcta aatgatccgt gagtttggtc aattgttcgt
    11101 catttatttg tcgattttca gtggtcgcca gaggaaatct cgaatcgttt gaagcatgaa
    11161 catatggact tttcaattag ttttatcacg atctaacgtg caatttgcaa tgatcttttc
    11221 gatacaga
//
LOCUS       DAFBSV010000089        11141 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.090, whole genome shotgun sequence.
ACCESSION   DAFBSV010000089 DAFBSV010000000
VERSION     DAFBSV010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11141
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.090"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            233..664
                     /locus_tag="LLB18_002317"
                     /pseudo
     CDS             233..664
                     /locus_tag="LLB18_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297423.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(721..1401)
                     /locus_tag="LLB18_002318"
                     /pseudo
     CDS             complement(721..1401)
                     /locus_tag="LLB18_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            complement(1475..2125)
                     /locus_tag="LLB18_002319"
                     /pseudo
     CDS             complement(1475..2125)
                     /locus_tag="LLB18_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
     gene            2450..2866
                     /locus_tag="LLB18_002320"
     CDS             2450..2866
                     /locus_tag="LLB18_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBK5245300.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            2863..3333
                     /locus_tag="LLB18_002321"
     CDS             2863..3333
                     /locus_tag="LLB18_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5245301.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            3347..4120
                     /locus_tag="LLB18_002322"
     CDS             3347..4120
                     /locus_tag="LLB18_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK5245302.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAAAPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            4134..4946
                     /locus_tag="LLB18_002323"
     CDS             4134..4946
                     /locus_tag="LLB18_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBK5245303.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            5000..5965
                     /locus_tag="LLB18_002324"
     CDS             5000..5965
                     /locus_tag="LLB18_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBK5245304.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            6081..8804
                     /locus_tag="LLB18_002325"
     CDS             6081..8804
                     /locus_tag="LLB18_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK5245305.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESKILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANCMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGEAIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            8817..9449
                     /locus_tag="LLB18_002326"
     CDS             8817..9449
                     /locus_tag="LLB18_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBK5245306.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKDLRKEVKPLLDFLKKRDIP
                     LALASSSPVVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTVALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            10348..>11141
                     /locus_tag="LLB18_002327"
     CDS             10348..>11141
                     /locus_tag="LLB18_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5245307.1"
                     /translation="MKNLQLKFIVDPSIVRWFRIINQFERNQLATKGELAKSNHVSER
                     TIQTDVNKMKDYFSESVQFVSTKSGYSFQKERPVLFLKQKEQLLENEILFELLGNVFY
                     GELEDMTELIDRFHLSEATFRRYLKQIQPVLEEYGLELSLYPLDLKGEEANIRKFFKD
                     FYYEGEMTPHTLVPPRDLHELVQATFYDKFEYFSIGTGTSPAEFYYSLYIAIERVRQG
                     KTIAIPQGLIERVIASENFRLMYSLKEAIQTNYQVALSEEEFCWLY"
BASE COUNT         3728 a         1720 c         2129 g         3564 t
ORIGIN      
        1 ttttaataaa tactacctaa ataaggtagt atttattttt gtgttttaaa agaggaagtc
       61 caatatatct atgggaaact tcttaaatat tatgttggta catgaaaata tacatccctg
      121 ctagactatt tacaacattt tactttgtac gtattcttgt tttaaaagga atgggataaa
      181 atataggtac aataactatt tgatgctaaa tataattaat ggaggagaga tagtgaacat
      241 acttaatgaa aaaagatatg tatggtttgc tggtaaaaaa tatattacta ctttcaaaag
      301 attatccgag ttaatgcagc agactgttaa aagtgctatg cctgaaggat acaagtttaa
      361 ttttgtttaa tcttcagtat ctactgaaag tatctatttt tcaattcttt ctgagagtag
      421 gctttttcat tttagaataa gttctcatgt aaagaaaact gatgttgata tatatacgtt
      481 ccgtacaaat aattataaaa atttaaatga tttgagtaga agtatcagtg aatatctcaa
      541 ggggaatagc tatctcaaga ttcgattttc acatatatta attttactac catatttgaa
      601 tgagaatttc accctaattc aagtagataa gtctttcatt gcctcaggta atcaaggaaa
      661 tatgaaggtt ctgttgcgaa gtttgaaaat caaacgcgcc ctctctgaac tccaaatatc
      721 ttaggctgtt attcccatta ataccttgat ttcagtagac accgaaaagc cgaagagcgt
      781 tccatttctt cggttctttt tatatattcc tcgaatggtc tccatgccct taatcgtgga
      841 agaggctgta cggagacttt gataaaattt atttcgtcgt ttaataggtc gatggtcttg
      901 ttctattaaa ttgttaagat acttcacagt tcggtgctct gtcttagtat ataaacccac
      961 actctgtaac tttctaaagg cggagccaag agaaggtgct ttatcggtca caattgcttt
     1021 cggctcacca aactatttat ggagtcgttt taagaaagca taggctgctt gcgtatcccg
     1081 tttctttcgt aaccagatat ctaaggttaa gccgtccgct tcaattgcac gataaagata
     1141 atgccaacgt cccttaattt tgatataggt ttcgtccatt ttccatgaat agaaggattg
     1201 tctatttttc ttcttccaaa gataatagag gactttgctg tactcttgta cccaacgata
     1261 aatcgtagta tgacaaacat ttattccacg atcatataac aattcctgaa cttcacgata
     1321 gcttagattg taacgcaggt agtaaccaac agcgacaata atgacgtctt ttttgaattg
     1381 tttgccttta aaatgattca ttactctgtc ctctctgtct tttttctcaa ttttacacta
     1441 aaatagattt tttggaaaac tttgcaacag aaccgccaat catatggaag ccaccgatta
     1501 ggtattttat gggtttagtc ggaaatgttt caagagcaat ttccatcata tcgataatgc
     1561 catgatgact acagccagta aagacaatca gaccatcttc ttgctcaatt acgaccaata
     1621 attcatctga aaaatcatca taaacaaatt tatcatccat ctttttgtat aaattcttgg
     1681 tggtcgagtt tgctttgcct agggggatga tatggaagct cggagcaagt tctgttttcg
     1741 tttttattgt atgtaaattc tcatgcattt taaggatttc atttttagga ataccaacat
     1801 acagaaacgt ggttaaaatc tttaaataat ggggtaaagt tacaccttca gctgtataaa
     1861 taggggcgtt tcctgatttt aaatatctta acccgccggt gtggtcagaa tgaccgtgtg
     1921 aaataatcac tgcctccaga tcattcaaag tttcccccat tttagtcgca ttatagacta
     1981 attttttatt agcgccagca tcgaagagat atttcttccc tgagtagtta attaagagag
     2041 ataacccatg tccactttta aagttcaaat ttattcttga gttttcaaat aaaaccttga
     2101 tttccactat aacatctcct ttcacatgaa cgtgtattca tatattgtag cacattaagt
     2161 tctatttttt gttgtaatta ccgaaaaaaa tattaatgga cgctttttac gctttatttc
     2221 gtatgtggaa gaaaatttct taggatgtgg cgggggattg gggcaaagct aaattccaat
     2281 tacagtgatc atttaattag acacctttaa atacccacac tttcatcaac actataattt
     2341 agggaaagaa aagtgttggc atgatataga aaaaccttta attaacagcg tttcctaaaa
     2401 ttggcacgca tcttgcttat agaaaagcgt aaggatagga ggaatgaaaa tggcaactat
     2461 aattcttgcc agccatgggg aatttgctca aggattaaag caaacagcga caatgattat
     2521 tggagatagt gtaccaattc atgccttgtc agcatttaga gatgaagatg aatctatttt
     2581 ggtacaaata aaaaaacttt tagccacaat agatatagaa gaaacctaca ttttaactga
     2641 tattctaggt ggtagtgtga ataatgatat gctcactatt attaaagagt atgagggatt
     2701 gcaattaatt actggaatga acttaccttt agttatttct attgcaacct ataatggaaa
     2761 aattggggaa agtgagctag aaaagcttat taaagagagt caacaatcag tgattgattg
     2821 tagaaaatta ttagtagaac aacttactgg aggagatgac ctatgattaa gttagtacgt
     2881 attgaccatc gtttgttgca cggacaggta gtattttctt ggagtaaatc attaaatatc
     2941 aatcgtatta ttattgccaa taaagaggca gcgaatgatg aattcaaaaa aatgtctttg
     3001 aatttatcta aaccgactgg cattaaatta acaatttttt cagttgaaca gttactagaa
     3061 aaaatgccta aaatcgaaac acttaacgaa aatatcatgc ttatttttgg taatacaaaa
     3121 gaaattcgtc aattttgtga agcctatcct aaagtacaag aaatcaacta tggagggata
     3181 atcaaaaaag aaggttccaa gcaatttagt aatgccattt tcttgaatga atctgagcaa
     3241 gaagatgcca aaaaattaaa agctcttggc attaaacaat ttattcaaca ggtaccaact
     3301 tctaaaaaag aagatttgaa tacaatgtta taaaggagga atgaaaatgc tcgttcagtc
     3361 aattggttta gggttaatcg gtgttttttg tattttagac tcaaggcttt taggaagaat
     3421 gaattttgaa cgaccgttga ttgtcagtac gcttgttggt ttggtacttg gagacatgga
     3481 aaaaggatta attgttggag cctctttgga attgatgtcc ttaggattag taaatatcgg
     3541 agctgctgca ccacctgata tgaatatggc atcaattatt gctacagcct ttgccatttt
     3601 atcaaatgcg aatgcagaag cagcattaac gattgccatt ccaatttcag tgttaggtca
     3661 aatactaggt atcttaatgc ggacgatttt gtcaaatttg actcacgttg cggatcgctt
     3721 tatcgaacaa gggaaattta gccaagcaag gagaattcat atactttatg gctcgggatt
     3781 atatgctctc atgtatttta ttcctatttt tctagcaatt tattttggaa cgaatcttgt
     3841 ttctcagatt gttgatgcga ttcctgagtg gctaacaaat ggcttaacgg ttgcaagtaa
     3901 aattttacca gcatatgggt ttgcgttgtt attacaaacg atgttaacga aaaaaatggt
     3961 gccattttta ttacttggat ttttaattac tgcttattct ggattgggaa tcattggtat
     4021 tgcagccttc gcatgtattg ttgcgtttgt catggttcaa gttcaaggta aaaactcaaa
     4081 tggtaaccaa aatgagccag atccattaga tgacttataa ggaggtagat taagtgaaag
     4141 agaaagatca aaatgcatgg aaatatcggc agttcttatg gcgttcatgg gcaattcaag
     4201 cctcatggaa ctatgaacga caaatgaaca tgggttttat gtacggaatt gcaccaattc
     4261 tagataacat ttacaagaat ccagaagatg aagcaatgaa gaaagaagct tacgagcggc
     4321 atatgatgta ctacaactgt acccctcaaa caagtgcatt tgtgttaggg ttaactgctt
     4381 ctatggagga gcaatactac gaagaccaag aaaactttaa tccggaatca atcagtgcag
     4441 tgaagacttc tctgatggga ccgctatctg gtgttggtga ttctttcttt caaggaacga
     4501 ttcgggtatt agcctttgga ctaggaatta atttagccca acaaggtagt attttaggtc
     4561 caattctagc aatgttaatt tcctttgtac cttccttttt agttacttac tatggtggga
     4621 aaattggcta taacatgggg aataaatact tgtctaaact gtatcaagaa ggtttgatgg
     4681 ataaagtaat gtatgtttgc tccattgtgg ggttgatggt cattggttcg atgattgcca
     4741 gcatgatcgg gattacaaca ccaattcaaa tgggtaaagc ttttgtctta caagatgtat
     4801 tagatagtat tatgccacaa tttttaccat taggattaac cttcttcatg tactggttat
     4861 tgcagaaaaa ggtcaaaaca ggatggatgt tggcaatctg tttagtcgga ggaattattt
     4921 ttagtttgtt aggtatctta caataaggga ataaccaata aatttggttg aataatataa
     4981 ataaggagga attcaattga tgaattcaaa agaaattgtt aaagaaatcg tagcgaaaaa
     5041 agaggtaaaa tcaatcgtat ttgttggctg tggcgcttca aaagcggacc tttatcctgc
     5101 aaagtatttt ctagaccaaa atgcgaagca gttacggatt agtcattaca cagccagcga
     5161 atttaactat gcaacaccag catctgtaga tgagtcaact gtcgttattt cagcttcttt
     5221 aggaggtacg actccagaaa cagttgaagc taacgcagta gctaaagaaa aaggtgctac
     5281 agttattagt ctaacacgaa gcattgactc accgttaaca aaagatgcag attatgtaat
     5341 ttatcatcga tttgcagaga actatgctgc taaattagaa aaaacaggct actgtttaga
     5401 attggcagta gaacttttac atcaagtaga aggttatgac cattatgaag caatgcaaga
     5461 aggatttgct actatctatg atcttgccca aaaaagtgca gaatcagctc gtaaagatgc
     5521 gaagaaattt gctgaacgct ttaaagatga aaaagttatt tatgtaatga gtagtggtgc
     5581 tacacatgaa gtagcatact caacatcaat ttgcttgatg atggaaatgc aatggattaa
     5641 ttctggtacc ttccattcag gagaattttt ccacggacca ttcgaaattg tggataaaga
     5701 cgtaccgttt atattattaa tgaatgatgg aaaaactaga aatatagatg ctcgagcatt
     5761 aactttcctt gaacgctttg atacgaaaac agaagttgta gatgccttgg attatggctt
     5821 gtcttcacat attgctaaag aagtcttaga ctactttaac ccattcgtga ttactgcagt
     5881 atttagagtt tatgcagaag aattgtcaga agcaagagaa catccattaa ctaagagacg
     5941 ttatatgtgg aaactaactt attaaaaaat agatcaaact aaataaggtg gcttgagaaa
     6001 ttaagccacc ttgttttctt caatgtgatt ttatacatat ggtaaaataa ctagtacata
     6061 ttgtgaaagc aggtggcaag atgcagcgat taaatgacta tctttatcaa ctaacattgc
     6121 ttttgaaatc tacgccttca gataattatt cagctcgcag tatttcgcaa gctttacagt
     6181 tgaatagaag tacaatcagt agctacttaa atgaaggtgt tcgtgaaggg cttttcataa
     6241 aagtaaaaag ttacccggtt ttatttttac atagaacagc tcttgaagaa ctacatatca
     6301 cactgaataa ctccgaaata gaatcaattg aaagcttgtt aacaatttct caaaaacccg
     6361 cattagatca agtaattggc tctaaaggaa gtttgaaaga agcaattgat caaattaaaa
     6421 cggcagtctt atatcctgga aaagggttgc ctttattatt gatcggcgct agtggatcag
     6481 ggaaaacctt tctagcgaat aaaatatatg aatatgcagt agaagaaaag gtcattcaca
     6541 catcggcacc tttcatagat tataattgtg cacaatatgt gagcaatcca gagttactat
     6601 cctctgcttt atttggctac acgaaaggag catttaccgg agcaagccag gagcatactg
     6661 gtttgctaga aaaagccgat ggaggagtat tgtttttaga tgaagtgcat cgcttatctg
     6721 aagaagggca agagaaatta tttacattta tggatacggg tgaattctct cctatggggg
     6781 ataatagtat tcggaaaaaa gccgatgttc gattagtctt tgcaacaaca gaaaatatat
     6841 atacgacttt cttaccaact tttcttagga gattgccagt tattgttaat ctacctagat
     6901 ttcaacaacg tccgtcgttt gaacgtctgt cattgattga tgaatttttt gtttctgaga
     6961 gtaaaatttt agctaaggaa ctatctgttt ctgatgcatt gattcatttc ttaatgaata
     7021 gtgattttga aggtaacgtg gggaatatta aaaatattat caagtatgct tgcggaaacg
     7081 catatatcca ccagaagagt cagcaaacaa ttcaagttaa attattggat atgcctttag
     7141 agtacagtta taaattcaag gagcaactaa ataaacccag aaagaaaaga gcagatcgaa
     7201 tctactatcc agaagaaaca cgacaagtgc aactagaaag aaacaatcag ctttttgttc
     7261 aattttttga ccaattactt actggattct ctgaagtgat tgaaaataac aaggatatta
     7321 aactattttt agaagaaatg gttaccaagg taacacaagt aatggatacg cttatttttc
     7381 aagaggatta cgaaaaagag cagtctttat acgccattct aaactatcat attcgtcaaa
     7441 gtattgattt tatgcgagaa agctacgggt ttgaacaaga tggtaaccgg gtagtcgctt
     7501 tggccaacta tctatatgtc aaggataatc aagtgatttt tgaaaatagt cttcaagaaa
     7561 agaaaaccaa agatcagctt aacgaatttt ttgctaatgt tcttgaaacc ccttattggt
     7621 atgcaaaaaa aatcttaagc cttttatctg agtgtttaga tcaacctgtg tatgaagagg
     7681 acattttctt tattacgcta tatttttata gtttgaatgt cacgaatgtt aaaacaggta
     7741 ttaagagtat tgtgctagct catggttatt ctacagctag tagtatggcg aatgttgcca
     7801 actgtatgct gaataagaac gtttttcaag cttatgatat gcctttagat attacattag
     7861 agaaaattga agcaaaattg attcaattcc ttggagatta tcgaacagat tcaggcttga
     7921 ttttattggt agatatgggt tcactaaacc aactaggcgg tttattagtg aatcatctaa
     7981 atggaccact gttaatcatt gatcatatca atacaccgtt attattggaa gtcggccaac
     8041 aagtattaaa caataaaagt atcaccgaaa taggagcaga aattgaaaca agtcttactt
     8101 tcaaaaagca gttactactt cccaagaaaa agaaaaagaa agccatcatt acttgttgtt
     8161 atacagggat tggtagtgcg acccagattc aggagatttt aacgaaatgc ttgaaagatg
     8221 cagttagaga attagtaatt attccgtatg attacaaaaa gctgttagaa aacaagaatt
     8281 ttgagactcc ttttcaatta tacgatgtca tcatgattgt aggtacagaa gatcccaaaa
     8341 ttaatcagat tccatatatt ggattagatc gcctgattaa tggggaagca attggcgaat
     8401 ttgttcatta cttggaaaaa gagctgacta ttgaagtgaa cgatttacaa aaagaattaa
     8461 ttttcaattt ttcaattagt aaaattgtcg aaaatttaac cattttggat ccagataagg
     8521 tgctatcttt tgtacaaaaa gcaattaaag aattatcgaa gttattaaat tttgattttt
     8581 ctaataatca gctgtttttg ttgtaccttc actgtagttg tatgattgaa cgaattgtac
     8641 gtaaagaaag tgtggatgag caagaggaca ttgaagaata tatgcaagca aatggagaaa
     8701 taatggataa aattcatagc gctttttttg agattgaaag ggaatacaca attgaaatac
     8761 cagatttaga gttgcgatta ttgagcgata ttgttcaagg ataggagtga attcgaatga
     8821 caatgggagt aatttttgat atggatgggg tactcataga cagcgagaca ttttattttg
     8881 agagaagaat gaacttcttt caagaactgg agatagatcc aggatcaaac cagattgatg
     8941 attatgtggg gaaaacagaa gctgcaatat gggaaacatt agttcctgag gacaaatcat
     9001 taagagagga actttatccg aaatatgtag attatcgaaa aacgcatcca attgatttcg
     9061 ctaaagattt acgaaaagaa gtgaaaccgt tacttgactt cctcaagaag cgggatatac
     9121 cattggcact ggcatcttct tctccagttg ttgagataga gagtatgctc attcaatgtg
     9181 aacttactga atatttttcc tttgttataa gtggtgagtc attaaaacaa agcaaaccac
     9241 atcccgaaat atatttaaaa gcgaaacagc aattagactg tgacttcttt attgcagtag
     9301 aggattcaac gattggtatt aaatcagcaa aggcagcaaa tatctatacg gtggcactaa
     9361 aacaaccaat gcaaatcgat cagagtgaag cagacataca aattgaaagt ctacaagaac
     9421 tggaacaaat tgttttagaa aaaggttagt gaattaatgg aaataaggct atatatctgt
     9481 gctagctatt ttgactaacc aaaaaaactt gctataattc aggtgtagta aaaggtgctg
     9541 gtaacacctt ttacgaaaat gcttcggcag tgataatggg attggctttt taagtttttt
     9601 attttgttcg caatccctaa ggtcatgtga atgatcctag ggattgctag aatattttgc
     9661 aacattctat ctatttcaga acgtaacctt ccccagttca ttgggattca ttagcataca
     9721 accaacattt caaaaagaaa ttgcactaca ccattattag ctattttgac taaccccaaa
     9781 aaacttgcta taattcaggt gtaggtaaaa ggtgctggta tcacctttta cgaaactgct
     9841 tcggcagtgg taatgagtgt ggcttaaagg actagtcctt taagcttttt actttgttcg
     9901 caatctctaa gatcaagtta atgatcgata agattgctag aatattttgc aacattctat
     9961 ttcagaacgt aacctttccc attccactgt gattcattgg caaccctcct cacaaccaac
    10021 gtttcaaaag aaattgtaaa gttgttgggg taccacgacc gaacaatact acacctgaat
    10081 gatagtaagt tgtctcatta agtatagcat atcctctttt tgggtaaata gaaatcggtt
    10141 acatttttta tccaagacca agttttttca tttggtctta tttgctatac ccaaacaatt
    10201 ccgcagtata gtcgacggta ttgattttat caggtgagta atagaaactt gttttccttc
    10261 cccaaaacat tacctataaa ggagaaaaaa tggtatcgta attatatagg tataggatga
    10321 aatttttttc taagaggagg gttgttgatg aaaaatttac agttaaaatt tattgttgat
    10381 ccatcgattg tacgctggtt tcggattatc aatcaatttg agcgcaatca acttgccaca
    10441 aaaggagaat tagcaaagag taatcatgta tctgaacgaa ccattcaaac agatgtcaat
    10501 aaaatgaagg actacttttc tgaaagtgtt caatttgttt caacgaaaag tgggtattct
    10561 tttcagaagg aaagaccggt tctttttctc aagcagaagg agcaactact ggagaacgaa
    10621 attttatttg agttgttagg gaatgtcttt tatggcgaat tggaagatat gacggagcta
    10681 attgatcgtt ttcatttatc tgaagcgact tttcgtcggt atttgaagca gattcaacca
    10741 gttttggaag aatacggctt agaattgagt ctttatcctc ttgatttaaa aggagaagag
    10801 gcaaatattc gcaagttttt taaagacttc tattatgaag gggagatgac gccccatact
    10861 cttgttccac caagggatct tcatgaactt gtgcaagcta cattctatga taaatttgag
    10921 tatttctcga ttggaacagg gacttctcct gctgaatttt attatagttt gtatattgcg
    10981 attgagcgtg tgagacaagg aaaaacgata gccattcctc aaggtctgat tgagcgagta
    11041 attgctagtg agaattttcg cttaatgtat tccttgaaag aagcgattca aacaaattat
    11101 caagttgctt tatcagaaga ggagttttgt tggttgtatt t
//
LOCUS       DAFBSV010000090        10897 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.091, whole genome shotgun sequence.
ACCESSION   DAFBSV010000090 DAFBSV010000000
VERSION     DAFBSV010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10897
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.091"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(132..1400)
                     /locus_tag="LLB18_002328"
     CDS             complement(132..1400)
                     /locus_tag="LLB18_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBK5245308.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(1631..2368)
                     /locus_tag="LLB18_002329"
     CDS             complement(1631..2368)
                     /locus_tag="LLB18_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBK5245309.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(2435..3004)
                     /locus_tag="LLB18_002330"
     CDS             complement(2435..3004)
                     /locus_tag="LLB18_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBK5245310.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            3132..4004
                     /locus_tag="LLB18_002331"
     CDS             3132..4004
                     /locus_tag="LLB18_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK5245311.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            4346..5218
                     /locus_tag="LLB18_002332"
     CDS             4346..5218
                     /locus_tag="LLB18_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBK5245312.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            5215..7173
                     /locus_tag="LLB18_002333"
     CDS             5215..7173
                     /locus_tag="LLB18_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK5245313.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(7424..8275)
                     /locus_tag="LLB18_002334"
     CDS             complement(7424..8275)
                     /locus_tag="LLB18_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBK5245314.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            8398..8865
                     /locus_tag="LLB18_002335"
     CDS             8398..8865
                     /locus_tag="LLB18_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBK5245315.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(9128..9610)
                     /locus_tag="LLB18_002336"
     CDS             complement(9128..9610)
                     /locus_tag="LLB18_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBK5245316.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(9710..10573)
                     /locus_tag="LLB18_002337"
     CDS             complement(9710..10573)
                     /locus_tag="LLB18_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBK5245317.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
BASE COUNT         3166 a         2236 c         2008 g         3487 t
ORIGIN      
        1 ttttttgagt aaacggtgtt caaaaacttg catctgcggt aataagttca accaaacaaa
       61 aaacatgaaa atctgttttt gtttggctgt tcttactact tgatgcaggg cagctttttc
      121 actacctctt tttaataacc ataaaatcct attccttcat atctccagcc catcggtgtt
      181 agccaatctc tttccttagc actcaaggta tagtgatggg taccagtttt ttcatttgga
      241 ttaaatagtc gataaattgg cttggaacca ccagaataaa aacttagacc ttcataacgc
      301 caaccgattt ttgttaaaga gttgatctca gattgtgcca ttgtgtaatg atggtctcca
      361 ctgtaaggat tgtataaacg gtagacaggt tgtccgctgt ttggtgcttg ccaagcaatc
      421 ccttcatatt cccagcctac agttggcaga taattttttt ctccggcatt caatgtatat
      481 aaatgttctc ctgtatgacg gttatacaga cgatacatcg gagaagttga agttggtgct
      541 gtatcatact gtgtcagatt ataggtttcg attacattgt tcaatgtaga accataatta
      601 ggcgcagtgg cataacgacc tgttagccaa gccgtagcat ctttgtaaga gttcgtattg
      661 cttttccatg caccggaata gtagtaaacg cctggctgaa aagaagtcgt cttcaatacc
      721 gttacgttat cttgcaatga ttctttgtac gaaggatatt ttctaaaagc ggcattcacc
      781 gtaatccatt gcccattcac atattccgaa gtaggcatcg taacagattg gccattatag
      841 cttcctttaa tcccaaatag attgtaatta ggggcagaag ccaaagtact gttcccccag
      901 ccactttcaa cgatggcttg agcaatcatg actgatgcat ataagtcatt ggcacttgcc
      961 aaactttgtg cagttgaggc aatactatca atgaacgctt gttgagaatt agcagatgag
     1021 cgagcataaa aagcatagcc agtatagttt tcgaattcag acaaatctgc ttgatgggta
     1081 tgtgtcaatg tttgcccatc tgtcaattgg ttcgtgattt cttctgcatt ctctggattg
     1141 ttctgagctt ctgctgatgt actgtcttcg gtttgtgttt gttctgttgt ttcagttgtt
     1201 ggttcttcgg ttgaaattgt attttctgag acagtagctg actgcaaagt actctctgta
     1261 tcgttttcaa ttcctgtttc tgaagaactc gatgtctgag ttgcgacagt ttctgtcgat
     1321 tcttcagcta gcactgttgt gttggcaact gctagatttc ctaaaagaat aacgctaaat
     1381 aataaattct ttgctttcat cttttttctc ctttgaatta tgaaactttt cctaaataac
     1441 agtgtaacta aaaaagtaaa agcaagtcaa tgtccatatt taaataacat ttgtttcttt
     1501 ttgataaatt tgctttttct acataaaaag acgtaaatga agaatattct tctccattca
     1561 cgccttaaat tgatggtcgt ttgaataact atttaacaag taattctctt tggatattat
     1621 ccgttatgga ttatacttcc tgtgtcgtcg gacggataat catgttactg acagacatcc
     1681 ggtctggcgt ttctatcgca aatgctacag cagaagctat atcttcggag gtcaatcccc
     1741 attctttttg cgcttcatga agttcaagag cagccttttt gtcgctgatg gtttgatata
     1801 attcagtttg aacagctcct ggagagatga tcgtagattt gatgttattt tgccgttgct
     1861 cttgacgtaa tccttccatg attgcacgga cagcaaattt tgttccgcaa taaacggcgg
     1921 aatcaggata aacaacatgt cccgccacag aatcagttga aatgatatgc ccagattttt
     1981 gtttttccat gattggaagt acggcggaaa ttccatttaa cacacccatg atgttgatat
     2041 caagcatatt ttgccattca tcacggtgac cttcaactaa tggagcggtt ggcatgattc
     2101 ctgcattatt gtacaataca tcgattcgac cgaacttttc catcgctaaa tcgataactg
     2161 cttggacttg tgcaaaatct cttacatctg ctgtttgaat atatagctca gcttctggta
     2221 aagattcttt tattgctttt aggcgatctt ctcggcgtgc agctataact agtttagccc
     2281 ctttttctgc taatagcttc gttgttgctt caccgattcc gcttgaagcg cccatgatga
     2341 caatcacttt ttctgataaa tcattcattc tattctcctc ctgttttgaa aaatctcttg
     2401 cttatactca ctatctctta tttcatctta ctgttcaaat aatccgttcg acaggtttga
     2461 cgattttggc agggattcct gcaacgatgg tattgtctgg gacatctttc gtaacagttg
     2521 cattcgctgc aacaatggca ttctcgccaa tcgttacgcc tggcagaata gttgctcctg
     2581 ctccgatcca agcatttttc ttgatgtgga ttggctttac tgacaagcct cttcgttctt
     2641 ttggatcggt tagatggttc accgtgatga ggttgacacg aggaccaatc aatactgaat
     2701 cttctaaaca gatgccacct aagtcaacga acatcacttg acgattgata aagacatttt
     2761 tccctatact aatatgtttg ccgaaatctg tataaaaagg cagcagaaca gtcaccgtat
     2821 catctacttt gtcactaatg atattttcta gccgtttgcg gatatctgct ggttcatggt
     2881 acccagtatt cagcgctgct aaaggctctt cgttttcagc ttggatctga tggatcactt
     2941 caaagagcgg atccgttact cgaatctctt tattgacgat ttgtttttcg atgaggcttg
     3001 tcattttgct ccctcctttt atccttactt tataacggac ggcttatcat gtctaatact
     3061 tataaaacat acttaactat tccttttaac tatacttagt ggtatgcttt tttaaaaaca
     3121 ggagggaaaa aatggatatt cgtatactga cgtatttttt agcagtagct agagaaaaaa
     3181 atatcagccg agcagcaaaa tctctgcata tcacgcaacc tactctctca aaacaactga
     3241 aagatttaga agaagaactt ggtgtgacac ttttcactcg gggctcccga gagatacagt
     3301 tgacggattc tggtcgatat ctttattcaa aaggaaaaga aatcttgtcg ttggtagaaa
     3361 aaacggcgaa caatttaaca aatgacgcaa tcatctctgg agaaatctac attggcggag
     3421 gcgaaactaa agcaatctct ttcatttctg atagccttca ttcgttgatc aaggcgcatc
     3481 ctgatatcca gtttcattta tatagcggga atgcagatga tatcatagac aaactggata
     3541 gcggattact tgattttgga ctcgtaatcg aaccgacaaa caaacaaaaa taccagtcat
     3601 ttcgactgcc agcccaagat cgttggggac ttttgataca tcgaaatcat cctttagcaa
     3661 agcaaaccgt catccatccg caggaactga aaactgttcc tttgatcatt tcccggcaaa
     3721 cgtcagtgga cagtcaacta gctgaatggc taggtttcag catagatcag ttatcgatcg
     3781 tcggaacata taacttattg tacaatgctt ctttgatggt cgataacggg acttttggtg
     3841 cattagctct agatgggatc atcaatactt atgggacgga aaaaatattc atcccactcg
     3901 atccgccatt acaagcttca ctgaatctca tttggaaaaa agaccagcct ctttctcctg
     3961 ctgctcgtaa atttttagat gtcctaacgg agaaatacag ttaagtagag tttttttcct
     4021 tcgctttcag ctttttaaca acgaataaga taagcaaaag atccaacgat taaataacat
     4081 aagtttctta atttatttct tccttttatt tctgataatt ccagtaaatt actataatta
     4141 taaaaaaaga attgacaaaa cataactgtc tatataaaat tgattacgtt aacaataatt
     4201 cgtttcatgt gactagatca tactaggcat gaaaaatctc tgaggaacat ggtttcccta
     4261 ggaggttttt cgtgtctatt tttgtttggc cgcaatcaac tggtctagca aacgtgaaaa
     4321 ccaaatcttc aaaaagggtg cgcgcatgaa aatcaaaaag atctttaatc aaaatgcagt
     4381 attggtagat gacggtggac aggaaaaagt agctattgga aaagggattg gatttgacag
     4441 aaaaagaaat gatttgattt ttgatcgtga tgtcgaacgg atatttgtca tggaaccaga
     4501 aggtcaaatc aagttgcaaa atttacttaa tcagattgat gaacgctttt tatttgcagc
     4561 agaaacgatc attgatcatg cggaaactgt tttgatggaa aagttgaatg aacatgtatt
     4621 gatcgctttg accgaccaca ttgctttttc tgcggagaac attaataacg gtatcgtcat
     4681 ccgcaacaaa cttttaagag aaatcgaagt gctttacagt gatgaattca gtattgctca
     4741 atgggcagta gagtatctga caaaagagct tgggattcca tatacttatg acgaagcagg
     4801 atatatcgca atccatattc acagcggacg aagcggtcgg aacaataacc atcgcagtat
     4861 ccgtgaagtg acgattgtat ctgacatcat ccatttagtg gaatcagaat tggaaacaga
     4921 tatccattca gaaccatttt cactgaatta ttcaagactg gtgaatcatt tacgactact
     4981 tctacaacga acccatgcgc aacaatatgc tgttttagac acggaaatcg tagaaatggt
     5041 caaacgaaaa tacccagaaa gctataagat ttctaaaaaa atccgtgtgt tgctgaccaa
     5101 agaataccag ctcgcgatca cgaaagaaga actgggttac ttggccatcc atatcgagcg
     5161 tttaagaagc gcaatcgtac aaacaaatgt taacaatcat gaggaggaaa aaaattgaaa
     5221 gcatatctac aacgaatggg acgttccctt caacttccag ttgcggtctt acctgctgct
     5281 gctttactag tagggatcgg aaactggtgg gcatcttata gtaacgacat tgtcgctcat
     5341 tttttacaag ctggcggtaa cgcagtttta ggtcaattac ctttgctgtt tgccgttggg
     5401 ttagcactag ggatgtcagt ggacaaatca ggtgctgctg ccttggcagg tttggtcgca
     5461 tttgaagttc cagtaaatgt tttaaaaact gattcagtag ctactttatt gaatatcaaa
     5521 ccagaatcag ttgatccatc ttttgctcag atcagtaacg tatttattgg tattattgcc
     5581 ggattgattg cggcagctct ttataatcgt ttccacgaag caaaattacc gatggcttta
     5641 tctttcttta gcggcaagcg tctagtgcca atcttggctg cctttgtcat gttgctgatc
     5701 agtgcagtgc tactgctcgt atggcctccg gtttactctg ctttagtttc ttttgctaaa
     5761 ttcattttga gtttaggctg gggtggtgca ggtctttatg gcttcttcaa ccgtttactg
     5821 atccctacag gattgcatca agcaatgaac tccgtgttct ggtttgacgt agcaggaatc
     5881 aatgatattg gtaaattttt ggcttctgaa ggaacaaaag gcgtaacagg aatgtatcaa
     5941 gctggatttt tcccaatcat gatgttcggg cttccagcag gagcatatgc tatttacaga
     6001 aatgcacgtc cagaaaacaa agcaaaaaca gcttccttga tgctagcagc agcttttgct
     6061 tcattcttta ctggtgtgac agaaccactt gaattttcat ttatgttcgt tgcttggcca
     6121 ttatatgtct tgcatgcaat tttcactggg atttctttag cagtgagtgc attcttccat
     6181 tggacagcag gatttgcctt tagtgccgga tttgtcgatt acttcctatc tttgaaaaat
     6241 ccgattgcga atcagccatt gatgttgatc gtccaaggat tagtaacagc agtgatttac
     6301 tactttggct ttaactttgc tatcaaaaaa ttccatctga tgactcctgg ccgcgaggaa
     6361 gcagatcttt cagatgacga tactgcaacg actaattcag acaataaata tgcggcacaa
     6421 gcaagcaaaa tctacgctgc attaggcgga gccgacaatg taacttcgat cgataactgt
     6481 actacacgcc ttcgtttgca agtcaaagat acaggcctga tcgatcaaaa taaaatcaaa
     6541 gccactggcg tacctggtat gaagatcatc gacggaaaaa atgcgcaagt catcgtaggt
     6601 acagaagtac aattcgttgc agatgagatg gcaaaactac atggtggtgc tgcagcacga
     6661 cctgcacaaa caaacaccgt ggttaaaaca gaaacatttg ccggtgaaac gatcgaacaa
     6721 gatatttacg ctatcgcaaa tgggaaactg attccaatca ctgaagtttc agatgatgta
     6781 ttcgcggaaa aaatgatggg tgacggctat gctgtattac cagaaaatgg agaaatcttc
     6841 tctccaatcg ctggtacgat cacaaacatt ttcccaacga aacatgctgt cggaatccaa
     6901 acagatgctg gtatcgaagt cttgcttcat atgggcatca acactgttga cttaaaaggc
     6961 gaaccattca ctttatatgt agaagaaggt caaaaagtcg caagaggtca attgattgct
     7021 ttagttgatc ttgccgctat tcaatctgca ggcaaaaaca cggatatggt cgttgtattc
     7081 acaaatggcg acaaagtcca aagcttagaa atcgaacccg cacgtgatgt aaaagcaaat
     7141 gataaaatcg gctctgtttc caacaaagcc tgagccatcg tcttccccag acttttttat
     7201 cgataaacaa acaggagctg agacaaaaat cttgtctcag ctcctttttc cgaataaaaa
     7261 cggcgttctc ctgccaactc cgcggtaata agtccagcta aacgaaacat atgaagagct
     7321 attttttatt tgactcttct tattacttga tgcagaacag ctttttcaca aaatttttct
     7381 tcatactcaa aactaatcgg ctttttcaca acctctttat acattattcc tgatccaata
     7441 tttcttttaa tgctgcttca agagaagtta atggttttcc caatactttt tctaaatcat
     7501 cagaggaaat agctaactga tcctttttaa tatcatgttg gatcgctaaa aacatgtcag
     7561 ctgcttcttg agggaatccg gcttctttta gattttcgac aaacgctgca tcacttgctt
     7621 caataatttc taactcttta cctgtcgcac gctctaatgc cttggctaat tcttcatagt
     7681 cagttagatt gccggataat tctaagattt ctggagagtc actttctact agtacttttg
     7741 ctgcagcttc tgcatattca cgtttcaatg cccaacctgt ttttccattt cctgcagcat
     7801 aaacgaattg accagttttt aaagcctgcc caatgatagg taattcattc tctacatacc
     7861 aattattccg taaaaatgta tgggaaatac ctgaatcctt aatcattttt tcagtgaatt
     7921 ggtgatctgg cgctaataca ctgatcgagt gatcggcatc tgcaaaactt gtataagcga
     7981 tataagatac cccagctgct tgtgctgcct tcactacatt cttatgttcg gcttgacgat
     8041 ttcctggaac gccagagaca aaaagcaatc gatctattcc tttcaacgct tctttcattg
     8101 agtctaaatc atcataatca ccaatacgta tattaaatcc agcttctttc agtgcttctc
     8161 ctttttcttc actacgtact agtacataga tttcattttg tggaaccatc ttttttaaga
     8221 attccagcgc ataaccacca aaacctccag ttgctcctgt tactaaataa tgcatatttg
     8281 ccactcccta ttctttttat ttgttaagat ttacagctgt acatttataa attacacctt
     8341 tatcataaag agtgtggtaa gataagtcaa gcaaaaaaaa tgaaaggatg acaactgatg
     8401 aagtattctc tgcaatttag tgatgcaatc catgtacttg cctatattga aatgtttcaa
     8461 gatacccgat cactttctag tgagatgatt gccagtagta tcgaaacaaa tgcagcaaat
     8521 gtacgtaaaa tcatgagtca gctcaaaaaa tccggtttga tctttacaaa aaccggaaaa
     8581 ccgcagcctt cccttgccaa aagtccagat cagatttctt tactagatgt ctatcgcagc
     8641 atcgaaggta atacacagct tatccaagtc gatccaaaaa caaatccaaa ttgcgtcgtt
     8701 ggtgcgaata tccaagaagc tttagaagaa agctacgctc ggctgcagaa aaaggcagaa
     8761 gaagaaatgg ctaagatcac acttgatagt ctgatacata aaatagccgt tttggaaaaa
     8821 gaaaaaagac cagaaaacac aggcctcgta gagagatttt tataattctc tctactgtgc
     8881 ctgcattttt ctgatcggaa tcgtctacat aaattctttt attctccggg ggacaaaagc
     8941 cttgtcatgc ccctttttcc tctctaatgc tcaggtcaaa gcgctgaagt catgacgtct
     9001 tgataaacgg tgttcaagta gctgaccctc ggcattagtt ctgaaaaatg caaaatatgg
     9061 aaagctattt cccatttttc ctctctaatg ctcaggtcaa agcgctactt tcacgacctc
     9121 tatattatca tggtttattg actaccggta tccagatttc tcccatatat ttcccgttgg
     9181 taactcccat ttcgactaca gcatttggac ccccaacata ggcgtaatct tctacttctc
     9241 ttaaaacatg cccaaaggcc gtattcgtca aatcatttct taattcttca ggcgattctg
     9301 ctaaagcgct tacaacaaga tacgttcctt ttgggaatgg gatgattcgc gtagtgtttg
     9361 gaacatcctg actcgtttga acaccgacat agtacatcat tttcccgtta tagggttcgt
     9421 tgactgtaaa gaaataatga ttttcagcag cttgtttcaa tgcatctatt gttccattac
     9481 cgataacttt ttgctcaaat gcttgtttct ctgcagccaa accgacaaaa tccgtattgc
     9541 tactcttcaa ttccacacca atacccgtca ccgtaaaatc tggtttttct tcgatcctat
     9601 actttgccat ttctcccacc ctttctatta tattaagttc atcttacata aaattaaagg
     9661 gaaatgacac gattacgctc ttttttctag ggatattttt attttttaac tatttttttg
     9721 ctttcactgc aatccaaatc tcactgtaaa cattactgaa atcctctccc cattttgtaa
     9781 aagagatctc gggagcttcg actaacccat aatctgaaga aggaagccat tctgcataga
     9841 ttttccccca agtatcttgt aaagtttggg gaaatggccc tttattagga aaaatggccc
     9901 aagtgtgttc ttctatagca agcatttcta aatcagcgta cggattttct tttgtcgtag
     9961 caaagccaat catgtgcatc aaactgccct tttcttccaa gcggtctcca tcaaatccat
    10021 aagaaacgtt gattacttga tttggatata aatctcctaa cttatgcatc tcttcccttt
    10081 gagtctccgt gatcgtctgc gctaactttt gtatttcttg attgactcct tcaaatttga
    10141 caggaacttt tttcgccaca cctgccacat aaaactgttc tttcttttcg atacgaaatt
    10201 ccatcgattt tcctcctctg acatcaataa aaaatgtcaa gcgtggaaaa gatttttgta
    10261 tgccgtatct gctgatttct gaaggcagat atcctgacca atcacgaaaa gctcttgaaa
    10321 aaccttcgac tgtttcatat ccatatctaa acgccgtttc tgtcactctt gatccatcta
    10381 gaagatcgcg attagccaaa gccaatctac ggtttttgat atagtccatt agcgacatcc
    10441 ctgcaataaa cgtaaagatg cgttttaatt gatattcaga gattcctgta ttttcggcta
    10501 ttattttata ggaaagtcct tctgtcaaat gttcttcgat gtaatcgatc aattggttca
    10561 gatctttaag catatttatc ttcctccttg attgcctttt tatcatatta tcaaagaaag
    10621 tcaattactt gatgaatcag gaaccaattt agtcagatgt agaaaatgtt gtatggatct
    10681 aaagaaaatt ctcaagcagc gtttcgtaac ggataattgg tattatctgc ctatctatgt
    10741 tttaccttta gaaaaataaa ttttggggaa gacagattct aagtaaacaa agcggtaaaa
    10801 atatctttta ttcccttagt taatccgctt actacctact gtacaaagca aattgttgtt
    10861 caaactgctg atcagaacgc tgcttggatt tttcttt
//
LOCUS       DAFBSV010000091        10660 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.092, whole genome shotgun sequence.
ACCESSION   DAFBSV010000091 DAFBSV010000000
VERSION     DAFBSV010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10660
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.092"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            333..2279
                     /locus_tag="LLB18_002338"
     CDS             333..2279
                     /locus_tag="LLB18_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK5245318.1"
                     /translation="MIERHVNLLKLLSRQEDFKPASFFSDKLAVSTKTIYQDIELLED
                     YVVNYQVTIERLPSLGIKLIGDRKNVEHLISSVENYLEKDIYSPEKRRVEIIKEVLFG
                     DKPVSLTHLSQSFMVSKTSLYNDLRIINKIIGSGEVKLQSSAEGISFTGNEQAIQRAI
                     KQLVFYYANDMESKTFFQVLNMLFDSKVISVIHDLLFNDYSELTEKVSDYYVRSLIST
                     LVIQCNRLLKGHHLTVEEEFLFNSIRYMETYIVANGLIEELKAKLNLPFYDADKEYLC
                     RQLFAHRVTNNLKTSNEEYAMSVHKLIERMSEIEKIDLTQNDRLYQSLLYHVPAMVLR
                     LKKGIKIQNPLLENIKSQYSELFSIVWYAMSILEEEFDVTLTDDEVSLILIHFQIAIE
                     DQSKANNIIIICQYGISSAQLIYNKVRRFLPAKDNVEISTLDKFHLAEIGEVDLIISS
                     LSFDAGGIPLVRVSPLVSKTDYMNIMEAYTKYLIEEPSRFIQNELIPKAVKVPTISKF
                     VQSSLVKTGVQVESKEECLDLMISELEANSLVTEEFRASIFSREKMGNTNLESGVALP
                     HANPSMVIESNIFIVALKNAINWGDRKVKLVIMVSLAEEDVSEIRGVYEELYQFIGQK
                     EMVDRLLQVHDSEKLLRIFQQKGE"
     gene            2282..2737
                     /locus_tag="LLB18_002339"
     CDS             2282..2737
                     /locus_tag="LLB18_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK5245319.1"
                     /translation="MYLDKELCLFQLEVKDQKELFQVMSEQLKNAGCVKDSFLEGITN
                     REQEFPTGLEVNQIGFAIPHTDSAHVNSSQICFASLKEPLVFSDMTDKSHEIPVRLVF
                     MLAMSQPHEQIDTLQNLVSLFQNEEKVNELLACTTKEAFIELVHSAGVY"
     gene            2751..4079
                     /locus_tag="LLB18_002340"
     CDS             2751..4079
                     /locus_tag="LLB18_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBK5245320.1"
                     /translation="MDIVLNAFEWFIGLGSNVFLPLIIFVIGILFGLKPGKAFVSGVT
                     VGIGSIGLGLVLSLLSDGLGTAIQQMGEQYGGGLNILDIGVGVGGPLAYSTSLGILMI
                     PISLILNFIFVVLGWTKTLNVDIWNFWFAIFLGMITQSVTGNFWFGLIGAIVAVILQW
                     FLADRTQKTVSEFFGYPGISITHMMGLSGVLFAKPVNWVFDRIPGFNKIDADAETLTK
                     RFGVLGDTVVIGLIIGIVVGIMAGYDVAGIGNLGIMTAAVMKIMPKMVAMFMEGLMPI
                     AEAAKEFTNKKLNGRQVNIGMDAALTVGHPTIMSTSLLLVPISLLLALILPGNKVLPF
                     GDLAFFAFAICLMIPYFKGNIVRSLVGCSLYVVTTLYMATWLAPIITDVFTLASFDVG
                     TAGLVTMLLCGLWPVGLFVLLASYFGVIGIGGLGVVLVGASIYMNKVKKA"
     gene            4113..4397
                     /locus_tag="LLB18_002341"
     CDS             4113..4397
                     /locus_tag="LLB18_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5245321.1"
                     /translation="MKKLLVICGAGHATSTIAVAKLSKWLEEEGLTDQVKIYQSKIAD
                     ELNKIDEYDAVVSTTIVPDVIKAKVTNGLGLLTGIGTDAIYADVKERLGV"
     gene            4399..4914
                     /locus_tag="LLB18_002342"
     CDS             4399..4914
                     /locus_tag="LLB18_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HBK5245322.1"
                     /translation="MRFHHDTLTIETVSGRPSYHDIRKELLDTVDTAGIENGMLVISS
                     PHTTCSLFFEETMHDTNFFGDDYLHVDINNVMETIIPKMTSENQYNSPGPKHIDFGTR
                     LSDPNYPAEKWVMLNTDAHLRSSIYGTNSMTLIVQEGKLLLGEMGRVYFVDWDQLRER
                     TRTINLMIMGE"
     gene            4930..5592
                     /gene="rpe"
                     /locus_tag="LLB18_002343"
     CDS             4930..5592
                     /gene="rpe"
                     /locus_tag="LLB18_002343"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBK5245323.1"
                     /translation="MTIAPSLLNAPIAEVKELFEILKEKNVDYLHIDVMDGCFVPDMA
                     FGPSVIKDIRPLTDVVFDVHLMIDTPEKIVTRFVEAGADIVTFHIEATKHAMKVIQLV
                     KEAGAKVGITFNPATPVSFIEPVLSLVDQVLVMTINPGTENKHFIQETVVKIEQLDVI
                     RKQNDYTYDIEVDGKIDNQTIKVCSKAGADIFVSGGFIFNGKNTPQEQIDKLNQSLEE
                     VK"
     gene            5599..6171
                     /locus_tag="LLB18_002344"
     CDS             5599..6171
                     /locus_tag="LLB18_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBK5245324.1"
                     /translation="MTNKDQNKNYLEAIILELQNNSKRINSVELEQFSEKIVQAKHIF
                     LAGAGRSGIAMQAFTNRLMHLGFSVSLVGEISSPHSQPGDLLIICSGSGETGSLKNLA
                     AKANQSGVSIALVTMKKDSSIGQLADSVLVLPGITKDENQREEDTFSQPMGSSFEQLA
                     FLTFDSLVLSLMDKTGESSETMFARHADFE"
     gene            complement(6358..7878)
                     /locus_tag="LLB18_002345"
     CDS             complement(6358..7878)
                     /locus_tag="LLB18_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBK5245325.1"
                     /translation="MTKMESELLVQIKQLTQLLEIQQQENTLLREQIAEMNRRLFGRK
                     KETPPVDGQIDLLDDSTFNEPEHTGQESQEPITVSSFKRRKRKGLKALSLEGLPEVPI
                     HYELKGADCLCEDCGHTLHDIGATRLREEPLYVPAHIEKQVIYQHAYHCRECEALGET
                     KIKKAPVPKPLINNSLGSSSIVTQSIWEKFVKKVPAYRQEKEWHALGFPLDRKKITNW
                     HIKVSEMVLEPIYNCLHQELSNQEVLHADETSYRVLNTHKEKTFYWLYASGKSEEKQV
                     VLYEHANSRSVDEPKSFLESFSGFLHTDGYAAYGKLPVNNVYCWAHVRRKFFEALGKQ
                     PSPKSHAKIGLDFCDKMFRIERTFNKLSAEERFVARKETLQPVMTEFFHWCESFAYLP
                     KSQLGKAVQYAVNHKDGLQIVLLDGRLELSNNRAERAIKELVIGRKNWLFSKSLKGAR
                     SNGIILSIIQTAVANGLNIRKYLNHLFTEIPNLSSMTPEALRAYLPWNQQIQEICK"
     gene            complement(8121..8306)
                     /locus_tag="LLB18_002346"
     CDS             complement(8121..8306)
                     /locus_tag="LLB18_002346"
                     /inference="COORDINATES: protein motif:HMM:NF017528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HBK5245326.1"
                     /translation="MPMLIDATALKHIFIVCGKTDLRKGIDGLAAFVIEEYDLDVYDQ
                     ALFLFCGTKKDRFKALY"
     gene            complement(8290..8472)
                     /locus_tag="LLB18_002347"
     CDS             complement(8290..8472)
                     /locus_tag="LLB18_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245327.1"
                     /translation="MNKKDIVPVQFSSAAQKSQIDTKPKLACRIKSEDKEIFIYNGMD
                     KYLLYTLLKELNANAH"
     gene            8713..8931
                     /locus_tag="LLB18_002348"
                     /pseudo
     CDS             8713..8931
                     /locus_tag="LLB18_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            9426..10025
                     /locus_tag="LLB18_002349"
     CDS             9426..10025
                     /locus_tag="LLB18_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBK5245328.1"
                     /translation="MKTVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLADVLEISRGRVVVKDRLAMKEQKTAKHNSVYISNKLRKTILEYVQQEFPDQ
                     LLQQDFDGYLFPSRKGTNEPLNRQSLWRIIHDAGTAIGLKDIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            10089..>10660
                     /locus_tag="LLB18_002350"
     CDS             10089..>10660
                     /locus_tag="LLB18_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage abortive infection AbiH family
                     protein"
                     /protein_id="HBK5245329.1"
                     /translation="MSTLYIIGNGFDLSHGLKTRYTDFSKWVEKSHSEIFDKIDTMIN
                     ENNEVRSTADDKIGWFNFESSLHELIQSPVFEDYVEESKDYLIGYGHEDWSDSAHHDF
                     QNMVYDYVVSLEELQQLFKEWIRKEIQPTIEHKIPKYQFSSDVLFFTFNYTDVLEILY
                     KQPKENIYHIHGSYDDIIIGHSENFDNFIG"
BASE COUNT         3525 a         1674 c         1990 g         3471 t
ORIGIN      
        1 taggactcaa ttgttcatag atgagcattt gtaattaagt tatattataa taaaaaaata
       61 cgaattttag tgacgccatt atattgtttt tatttttcaa ttgtaatatt tcatattact
      121 tccataataa ggagtatttt ctattggaat atcttagctc ttttaaggat ttctcctttt
      181 ttgtttctca ttttttaaga ttatttggat ttcctttaca acaaacttcc acaagtatta
      241 ttgacataga tgtaattgag ggaagggggt tccagtgcta gaataaataa tgaaaagagg
      301 taacaaatgc tagcgttaag aggtgaacaa gtttgattga aagacatgta aatttattaa
      361 aattattaag tcgacaagaa gactttaaac ccgcttcttt ttttagtgat aaattggcag
      421 tgtcgaccaa gaccatttat caagatattg aattgttgga agattatgta gttaattacc
      481 aagtaacaat tgagcgatta ccttctttgg gtatcaaact cataggtgat aggaaaaacg
      541 ttgaacattt gatttcatcg gtagaaaatt atcttgaaaa agatatttat tctccagaaa
      601 aaagacgtgt cgagatcatt aaagaagttt tgtttggtga taagcctgtt tctttaactc
      661 atttgtctca aagttttatg gttagtaaaa catcgttata caatgacctg agaattatca
      721 ataaaattat tggcagtgga gaagttaagt tgcagtcatc tgcagaagga attagtttta
      781 ctggtaatga acaagcaatt caacgagcaa tcaagcaact tgtattctat tatgcgaatg
      841 acatggaatc aaaaacattt tttcaagttt taaatatgtt gtttgattca aaagttatta
      901 gtgtcattca tgatttgcta ttcaatgatt acagtgaact gactgaaaag gtttctgatt
      961 actatgttcg gtcattgatt tctactttag ttatccaatg taaccgttta ctgaaaggtc
     1021 atcatttaac tgttgaagaa gaattcctct tcaatagcat tcgctatatg gaaacgtaca
     1081 ttgtggcaaa tggtttaatt gaagaattga aggcaaaatt gaatcttcca ttttatgacg
     1141 cagataaaga atatctatgt cgtcaactat ttgcacatcg tgtgacaaat aatttaaaaa
     1201 ccagcaatga agagtacgct atgagcgttc ataaattgat tgaaagaatg agtgagattg
     1261 aaaaaattga tttgactcaa aatgatcgat tatatcaatc cttattgtat catgtgccag
     1321 caatggtcct tcgtttaaaa aaaggtatta aaattcaaaa tccgttatta gaaaatatca
     1381 aatctcaata ttcagaactc tttagcatag tatggtacgc catgtccatc cttgaagaag
     1441 aatttgatgt gactttaacg gacgatgaag tttccttaat tttgattcat tttcagattg
     1501 ctattgaaga tcagtccaaa gcaaataata tcatcattat ttgccaatac ggtatttctt
     1561 ctgcgcaatt aatttacaat aaagttcgac ggtttttacc agcaaaagat aatgtagaaa
     1621 tatcaacttt agataagttt catttagctg aaattgggga agttgatttg attatttcct
     1681 ctctttcctt tgatgcaggt ggtataccct tagtaagggt atctccattg gtaagtaaaa
     1741 cagattatat gaatattatg gaagcttata ctaaatattt aatagaagaa ccttcgcgat
     1801 ttattcaaaa tgaactgatt cctaaagcgg ttaaagttcc caccatatct aaatttgttc
     1861 aatcatcttt agtaaaaaca ggagtacagg tggaaagcaa agaagaatgt ttggatttga
     1921 tgatttccga actagaagcc aattcattag ttactgaaga gtttcgtgct tctatcttct
     1981 ctagagagaa aatggggaat actaatttag aaagtggtgt tgctttaccg catgcgaatc
     2041 catcaatggt cattgaatcc aacattttta ttgtagcatt aaaaaatgcg attaattggg
     2101 gcgatcgaaa agtcaaatta gtcattatgg ttagtttagc tgaagaagat gtatctgaga
     2161 ttagaggagt atatgaagaa ctttaccaat ttattgggca aaaagaaatg gtcgatcgct
     2221 tgttacaagt tcatgatagc gaaaaattac taagaatttt tcaacaaaaa ggagaataaa
     2281 aatgtatcta gataaagaat tatgtttatt tcaattagaa gtgaaagatc aaaaagaatt
     2341 gtttcaagta atgtctgaac aattaaaaaa cgctggttgc gtgaaagata gtttcttaga
     2401 aggtatcacc aaccgtgaac aagaatttcc aactggatta gaagtaaatc aaattgggtt
     2461 tgctatccca catacagatt ccgcacatgt aaatagctct caaatctgtt ttgcctcatt
     2521 aaaggaacca ctggtatttt cagatatgac agataaatct catgaaatac ctgtacgttt
     2581 agtctttatg ttggcaatgt cacaacctca tgaacaaatt gatacactac aaaacttagt
     2641 tagcctattt caaaatgaag aaaaagtaaa tgaattactt gcatgtacca cgaaagaagc
     2701 atttattgag ttagtacatt ctgcaggagt ttattaggag gaatagagag atggatattg
     2761 tattaaatgc ctttgaatgg tttattggat tagggtcaaa cgtcttttta ccactgatta
     2821 tttttgtaat cgggatatta tttggattaa aacctggtaa agcatttgtt tccggcgtta
     2881 ctgttggtat cggttctatt ggtttaggat tagttttaag tttattatca gatggtttag
     2941 gaacagcaat tcaacaaatg ggggaacaat acggtggtgg cctgaatatc ctagatattg
     3001 gcgtaggtgt tggtggacct ttggcttact ctacatcatt gggaatttta atgattccaa
     3061 tttcattaat tcttaacttc atatttgtgg ttttgggttg gacaaaaaca ttgaatgttg
     3121 atatttggaa cttttggttc gcaattttcc taggtatgat tactcaatct gttacgggaa
     3181 acttttggtt tggcttaatt ggcgcgattg tcgcagtaat tttacaatgg ttcttagcag
     3241 atcgtacaca aaaaactgtt agcgaatttt tcggctatcc aggaatctct atcacacata
     3301 tgatgggatt atcaggagta ctatttgcca aaccagtaaa ttgggttttt gatcgtattc
     3361 ctggatttaa taaaatagat gcagatgcag aaacattaac aaaacgtttc ggtgttttag
     3421 gtgacacagt tgttattggc ctaattatcg gtattgtagt gggtattatg gcaggctatg
     3481 acgtagcagg aattggaaac ttaggaatta tgactgcggc agtgatgaag attatgccta
     3541 aaatggtagc aatgtttatg gaaggtttaa tgccaattgc agaagcggcg aaagaattta
     3601 cgaataaaaa gttaaatggt cgccaagtaa acattggaat ggatgcagcg ttaactgtgg
     3661 gtcatccaac tattatgtca acttctctat tgcttgtacc aatctcatta ttgctagcac
     3721 taattcttcc aggaaataaa gtattacctt ttggagattt agcattcttt gctttcgcca
     3781 tctgtttaat gattccttat tttaaaggaa atattgtgag atcattagta ggatgttcgt
     3841 tgtatgttgt tacaacatta tatatggcaa catggttggc accaattatc actgatgtgt
     3901 ttacattagc aagtttcgat gtggggacag caggattagt aactatgttg ttatgtggat
     3961 tatggccagt agggttgttt gttttattag catcttactt tggtgtaatt ggaataggtg
     4021 gattaggagt tgttttagta ggtgcttcta tctacatgaa caaagtgaag aaagcttaat
     4081 cataaaatta aaataagaaa gaagagatca atatgaaaaa attattagtt atttgtggag
     4141 caggtcatgc tacttctaca attgcagtag caaaattatc aaaatggttg gaagaagaag
     4201 gattaacaga tcaagtgaaa atttatcaat ctaaaattgc tgatgagcta aataaaattg
     4261 atgaatatga tgctgtagta agtacaacaa ttgtccctga tgtaattaaa gctaaagtaa
     4321 cgaatggctt gggcttatta acaggtattg gtacagatgc catttatgca gatgtaaaag
     4381 aaagattagg tgtttaatat gcgttttcat catgacactt tgactattga aacagtttca
     4441 gggcgtcctt cgtatcatga tattcgaaaa gaacttttag atacagttga tacagcaggt
     4501 attgagaatg gaatgttagt aatttcgagc ccgcatacaa cttgctcact cttttttgaa
     4561 gaaacgatgc atgacacaaa cttttttggt gatgattatt tacatgtaga catcaacaat
     4621 gtaatggaaa cgattattcc aaaaatgacg agtgaaaatc aatacaacag tccggggcca
     4681 aaacacattg attttggaac aagattatct gatcccaatt accctgcaga aaaatgggtc
     4741 atgctaaata ccgatgcaca tttacgttca tctatttatg gaaccaactc aatgacttta
     4801 attgttcaag aaggtaaact tttattagga gaaatgggcc gtgtctattt tgtcgattgg
     4861 gatcaactaa gagagcgaac tagaacaatc aatctcatga ttatgggaga ataaacgggg
     4921 gaatagagaa tgacaattgc tccatcattg ttaaatgcac ctatcgcaga agttaaagag
     4981 ttatttgaaa tcttaaaaga aaagaatgtt gattatttgc atattgatgt aatggatggc
     5041 tgttttgtac cagatatggc ttttggacca agtgttatta aagatattcg tccactaaca
     5101 gacgttgtgt ttgatgttca tttgatgatt gatacaccag aaaaaattgt cacaagattt
     5161 gtagaagcag gagcagatat tgttaccttc cacattgaag ctaccaaaca cgcaatgaag
     5221 gtcattcagt tagtcaagga agcaggagca aaagtaggga ttacttttaa tcctgcaaca
     5281 ccagtcagtt ttattgaacc agtattatct ttagtcgatc aagtattagt aatgacaatc
     5341 aatccaggaa cagagaataa gcattttatt caagagacag tagttaaaat cgaacagtta
     5401 gatgtaatac gcaaacaaaa tgattatacg tatgatattg aagtagatgg caagattgat
     5461 aatcaaacga ttaaagtttg ttctaaagca ggggcggata tttttgtatc aggcggtttc
     5521 atcttcaatg ggaaaaatac cccgcaagaa caaattgata aactaaatca atcattagag
     5581 gaagtgaagt aaaagatcat gaccaataaa gaccaaaata aaaactattt agaagcgatt
     5641 atcttagaat tacaaaataa ctcaaaacgt attaattctg tagagttaga acaatttagt
     5701 gagaaaattg ttcaagctaa acacatcttt ctagctggtg caggacgctc tggaattgcc
     5761 atgcaagcat ttacgaatcg cttaatgcat ttaggttttt cagtcagcct tgtcggtgaa
     5821 attagttcac cacattcgca acctggagat ttattaatta tctgttctgg ctcaggtgaa
     5881 acaggtagtt taaaaaattt agcggccaaa gcaaatcaaa gtggtgtaag cattgcttta
     5941 gttaccatga aaaaagactc gtcgattggt caattagcag attctgttct tgtattacca
     6001 ggtattacca aagatgaaaa tcaacgagaa gaagatactt tttcacaacc tatgggttca
     6061 agttttgaac aattagcatt tctcaccttt gatagtttag tgttatcttt aatggataaa
     6121 acaggtgaaa gctcagaaac gatgtttgct cgacatgcag attttgagta gtagatttta
     6181 aagataaaaa accattctct aaatgctaat tattcagcaa atatgagaat ggttttttta
     6241 tttgattaga cataacttaa taattcagta gttttgagcg taagcgtgtc atagaatggt
     6301 acctaaacac aaatagcccg atttgataca ctcaaatcag gttatttgtg gcttatatta
     6361 tttacagatt tcttgtatct gctgattcca tggcaaataa gcgcgtagcg cttcaggtgt
     6421 catcgaagac agattgggaa tctctgtaaa aagatgattt aaatatttgc ggatgtttaa
     6481 cccattcgca acagctgtct ggataatact caatataatt ccatttgatc tagcgccttt
     6541 taagctttta gaaaatagcc agttttttcg accgatcact aactctttga tggcacgctc
     6601 tgctcggtta tttgaaagtt ccaagcgtcc atcaagcaac acaatctgaa gtccgtcttt
     6661 atgattgact gcgtattgaa ccgcctttcc aagctgcgat tttggcaaat aagcaaaact
     6721 ctcacaccaa tgaaaaaatt cagtcatcac aggctgcaac gtttccttcc tcgctacaaa
     6781 cctttcttct gcgctaagct tattaaaggt ccgttcgatt cgaaacatct tgtcacagaa
     6841 gtctaatcct attttggcat gactttttgg ggacggttgt ttacccaatg cttcaaaaaa
     6901 ctttctgcga acatgcgccc aacaataaac attgtttacc ggcagctttc cataggccgc
     6961 gtaaccatca gtatgcaaga aaccgctaaa tgattctaaa aaactttttg gctcatcaac
     7021 ggaacgcgaa tttgcgtgct cgtagagcac aacttgtttt tcttcgcttt tacctgaagc
     7081 atataaccag taaaaggtct tttctttatg agtattcaat acccgatagc ttgtctcatc
     7141 cgcgtgtaag acctcctgat tgcttaattc ttgatgaagg caattgtaga ttggctctaa
     7201 aaccatttca cttaccttga tatgccaatt agtgattttt ttacgatcaa gagggaaacc
     7261 aagtgcatgc cattcttttt cttgtcgata tgccggcacc tttttaacaa atttttccca
     7321 aatactctgt gtcacaattg aagaggaacc tagactatta ttgatcaacg gtttaggaac
     7381 aggcgctttt ttgatttttg tttctcctaa tgcttcacat tctctgcaat gataggcatg
     7441 ttggtagatg acttgttttt ctatatgggc aggaacatac aatggctctt ctctaagcct
     7501 tgtcgcaccg atatcatgta aagtatgacc acagtcttca cacaaacaat cggcaccttt
     7561 taattcataa tgaataggaa cttcaggcag accttctaat gaaagtgctt tgagtccctt
     7621 gcgttttctg cgtttaaaag aagataccgt aatgggttcc tggctttctt gtccagtgtg
     7681 ctctggttca ttaaaagttg agtcgtctaa taaatcgatt tgcccatcta cgggtggtgt
     7741 ttcttttttt cgtccaaaca agcgtcgatt catttcagca atttgttctc taagaagagt
     7801 attttcctgt tgctggattt caagcaactg tgttaattgc ttgatttgta caagaagttc
     7861 agattccatt tttgtcattt ttacaccacc attctagcga ttttcttaca tctattatac
     7921 cattttatga caacgaaaaa cagacaaaat ccttgattta acaaggtttt cgtctaatat
     7981 atcgcacctt ttttcgtttc ttttagcgta catttttctt cgattgaaag gccagtcagt
     8041 aagacttctt ttctggaacg cggccattga aggtacccac tttcaaatct tttgtacatt
     8101 aatacaaatc cattttgatc ctagtaaaga gccttgaagc gatctttctt cgtaccgcaa
     8161 aataagaaaa gcgcttgatc gtaaacatca aggtcatatt cttctataac gaaagctgct
     8221 agtccatcaa ttccttttcg aagatctgtt tttccacaaa cgataaaaat atgtttcaat
     8281 gcagttgcat caatgagcat tggcattcaa ctcttttaac aaggtataca aaagatattt
     8341 atccattcca ttataaataa atatttcctt atcttccgat ttgattctgc aagctagttt
     8401 tggcttggtg tcaatttgcg atttttgagc cgcacttgaa aattgaactg gtacaatatc
     8461 ttttttattc attcgttttt ctccttctat atttgatagt ttaattatag aagaaagata
     8521 atcggcgtac gagatactat cctatgacac gcttacattt aatttaatat tttgcctcaa
     8581 attagccaca ctttttatag aactaagagg aaaaatgaag ttttcttcct attaatatag
     8641 ttgtttgaaa tcttaaatat agcgttttac gatgtaatgg gaagtatggt gaataaatca
     8701 actatgttcg tacgaagcat ttactcaact aatttaatcg aatctttcaa taaacaaatc
     8761 aagaaataca gccaccgcaa ggaacagttc caaaatgaag agtcgatgga acgtttctta
     8821 gtctcgtctt ttgatactta caaccaaaaa ttcctaggtc gcagtcataa aggtttccaa
     8881 caggccgaag gcgagctcga acaaatgctg agtcaaccga tggagaatta gaaacaatct
     8941 acagtaggga agaaccattg acacaaaatt attgacgctc ccaactaaaa gtgtcaaaat
     9001 aatgatgaaa tcatttagtt cttataaatt agaaaagaga aaataaatat tccatatcta
     9061 ctttattgga tccgtaacat gactaaattc tgaatacttt ttaaagctta tcatttggta
     9121 aaactgaata taagttaatt atatagactg aaaattttga attttcagaa tagaataact
     9181 taaaagtact gacaaaattt tttaaagggg caatattaat gttctgagat aatcaaatcc
     9241 taccgaaaat atcaaaaatc caatgtgaca caatcagatt gtgtctcatt cgagggaatc
     9301 acacaatccc acgtggctct aggcagaatt gaatttttgc ttggggcttt ttccttatat
     9361 tgattttgaa tgagacttat tatatgttat aatgcaatta agtatcattg gagagggcga
     9421 agaaaatgaa gacggtagaa cctattcgag acaaaaaaaa gatcgatgcg atgaaggcaa
     9481 tcttggcttc gggaaaatat ggccaacgaa atttggttct tttttcgatt gggatcaaca
     9541 ccgcctatcg catttctgat ttgcgtcaat tgaagctggc cgacgtgctg gaaatttcac
     9601 gcggtcgcgt ggtggtcaaa gatcgattag cgatgaagga acaaaaaaca gctaaacata
     9661 attcggtcta tatttccaac aaattgcgaa aaacgatttt ggagtacgtt caacaggaat
     9721 ttcctgatca actccttcag caagattttg acggttattt gttccctagt cgaaaaggga
     9781 cgaatgaacc gctcaaccgc caaagtctgt ggcgaatcat tcatgatgct ggcacggcaa
     9841 tcggattgaa agacattggc ccacattcca tgcgaaaaac gttcggttac tttctctata
     9901 aacaggggac caaaacagaa atcattcagt ccttgttgaa ccattcttct cagcgcgaaa
     9961 cattgcggta tattggtatt acacaagaag acaaagatac agctgtaaaa agcttagatt
    10021 tataatataa aagttaagtt taaacatgga tagttttaaa ttagtagatt gagtgttggg
    10081 aggaaagaat gagtacatta tatattatag gaaacggttt tgatttaagt catggtttaa
    10141 aaactagata cactgatttt tcaaaatggg ttgaaaaaag tcatagtgaa atattcgata
    10201 aaatagacac aatgataaat gaaaataatg aggtgagaag tacagctgat gataagatag
    10261 gttggtttaa ttttgaaagt agtttgcatg agttaattca aagtccagtc tttgaagatt
    10321 atgtagaaga gtctaaggat tatctcatag gttatggaca tgaagattgg tcagattctg
    10381 cccatcatga ttttcaaaat atggtttatg attatgttgt ttctctagaa gaattacaac
    10441 aacttttcaa ggaatggata cgcaaagaaa tacagccgac aatagaacat aaaattccaa
    10501 aataccaatt ttcgtccgat gtactattct ttacattcaa ttatacagat gttttggaaa
    10561 ttctatacaa gcaaccgaaa gaaaacatat atcatattca tggcagttat gacgatataa
    10621 taatcggcca ctccgagaat tttgacaact ttataggaga
//
LOCUS       DAFBSV010000092        10589 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.093, whole genome shotgun sequence.
ACCESSION   DAFBSV010000092 DAFBSV010000000
VERSION     DAFBSV010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10589
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.093"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(<1..364)
                     /locus_tag="LLB18_002351"
     CDS             complement(<1..364)
                     /locus_tag="LLB18_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5245330.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTF"
     gene            complement(367..1053)
                     /locus_tag="LLB18_002352"
     CDS             complement(367..1053)
                     /locus_tag="LLB18_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245331.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGG"
     gene            complement(1059..1730)
                     /locus_tag="LLB18_002353"
     CDS             complement(1059..1730)
                     /locus_tag="LLB18_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBK5245332.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            complement(1723..2064)
                     /locus_tag="LLB18_002354"
     CDS             complement(1723..2064)
                     /locus_tag="LLB18_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245333.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            complement(2242..2940)
                     /locus_tag="LLB18_002355"
     CDS             complement(2242..2940)
                     /locus_tag="LLB18_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HBK5245334.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            3027..3497
                     /locus_tag="LLB18_002356"
     CDS             3027..3497
                     /locus_tag="LLB18_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245335.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            complement(3540..3719)
                     /locus_tag="LLB18_002357"
     CDS             complement(3540..3719)
                     /locus_tag="LLB18_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245336.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(3706..4044)
                     /locus_tag="LLB18_002358"
     CDS             complement(3706..4044)
                     /locus_tag="LLB18_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HBK5245337.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            complement(4060..4263)
                     /locus_tag="LLB18_002359"
     CDS             complement(4060..4263)
                     /locus_tag="LLB18_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5245338.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            complement(4278..5054)
                     /locus_tag="LLB18_002360"
     CDS             complement(4278..5054)
                     /locus_tag="LLB18_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HBK5245339.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            5353..5673
                     /locus_tag="LLB18_002361"
     CDS             5353..5673
                     /locus_tag="LLB18_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5245340.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            5691..6122
                     /locus_tag="LLB18_002362"
     CDS             5691..6122
                     /locus_tag="LLB18_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBK5245341.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            6252..6713
                     /locus_tag="LLB18_002363"
     CDS             6252..6713
                     /locus_tag="LLB18_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBK5245342.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            6747..7382
                     /locus_tag="LLB18_002364"
     CDS             6747..7382
                     /locus_tag="LLB18_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HBK5245343.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            7495..8130
                     /locus_tag="LLB18_002365"
     CDS             7495..8130
                     /locus_tag="LLB18_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245344.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINSASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            8429..9484
                     /locus_tag="LLB18_002366"
                     /pseudo
     CDS             8429..9484
                     /locus_tag="LLB18_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            9743..9973
                     /locus_tag="LLB18_002367"
     CDS             9743..9973
                     /locus_tag="LLB18_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245345.1"
                     /translation="MMEEFIRKNISDEYADFYEQSNEKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            9979..10278
                     /locus_tag="LLB18_002368"
     CDS             9979..10278
                     /locus_tag="LLB18_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245346.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVLDARSDHRRYDYIKYTFVDPERYKD"
BASE COUNT         3491 a         1795 c         1690 g         3613 t
ORIGIN      
        1 taaatgtatt attaatagat gtattattat ctttgacttt ttcgtcaata ggggtattgc
       61 gtttttcgtc aatagggtat tgattaattc gtaggtacct attgattatt tgattggtac
      121 cctctttgta aatgatttcc cgattcaagt atccaaactt aatcaaatca cttacccatc
      181 gcgatatggt ctctttattc acaccatata aatctgcaaa gtactcattg cctgcccaac
      241 aaaagcctct ttcattacac aaggccgtta tctctccgta taacaactta gtatttggtt
      301 taagtctttt gtcgtacctt acgttggctg gtataatcgc ataataactt cgatgttctg
      361 tcatttttac cctccaatat ttaacttttt gattgttttc tggtttaatt tgatcccttt
      421 gatttgatat ttatttttga aattaatcac acctattttg tgcttctctg tgtgatggat
      481 tctgcagagt gctgcaaatg tgtactctgc atgatcaact tctttgcgct ttcgtcttcc
      541 tagcgctttg tcaaagtgat cgatgtcagc tcctgttttg ccacagatgc agcagactct
      601 ttttgtgatg catttgtaga agtaatattc ttgattcgca ggtaaaatct catagccttc
      661 tttgaaagga atatgatgtt caaagatgaa atctaagatg atatttgcta agacattggc
      721 atcactcaca gttgtattcg attcgtcttt caggcttatt ttgcgccctg tgacaccttc
      781 aaaacgaaag tagaagaatt ccttccagaa gtccgttggc atgcctgtat cgataaaaat
      841 atcgcctatc agcgcataga tgaagtttcg ttgctgtacg gtgaaacgtc taggatcaat
      901 aaaacgaatt tcaatgactc gatcaccatc gtagccgtca tacatcgtct ttagtcgatc
      961 aatgttcact tcctcattga tggttgcgct tatgtctttt cctttgaact ttttcagaac
     1021 cgctgaatat gaatcgatta atggtttaaa cactcatatc acttcttatc taattctttt
     1081 ctcttagctg ctattgctcg ctccatcaag gcacattgct catagcttaa ctgttcaata
     1141 gtttcaacgt tatcagctaa gagccctaat ttatctgtct gctcattaac atattcgatt
     1201 aaggttttgg tcatatcttt acccatctgc tcattgaaag cttctagaat cgtctctagc
     1261 atgtttaatt tctttgtatc gattctaggt ggtgttggaa tatcttcccc ttgaaataca
     1321 tataatccca gtccgtgtag agccaatgct ttcacaaagc atcgcttcaa tgagttattg
     1381 atttgcattg catttggttt aacaactggt tggtttcgat aatctaaaac aggaaataat
     1441 tcggtttccg tgtgtccttt aaccgttact gagacagata cataagtccc agtttcatcc
     1501 ataagaaaag gtttatattc ctcaacaaga aagtcttgat gagttccaga aacaaccctg
     1561 tagtgtttgt actcattaat agttaccgtt gcctgtggat cattcttttt cataatctcc
     1621 cacgcgtgag cccaagataa ataatcaaaa tttccttttt tcttgagaat tttatttaac
     1681 ttacgactaa aaagtttttc aaagttcgtt gtccctttga tttcactcat caaattctgc
     1741 ctccatttca gcaatgtatt tcttacctgg tccgtaataa gagatatcaa tcaagttatc
     1801 tctgtcgtac tcttctagcg catcaatcaa gccatcttcg atgacgtaaa tatattcagg
     1861 tttattcgaa tgcttcgata gatggataag ataaacatga tcccaaatag ttacatggtt
     1921 gcctaaatca tcttgatccc aagctagttc ttcattcgtc aaaagatttc gtctgatttt
     1981 tcgaccactt gtttcctcaa ttttcggctt gccccaatca ggatcaatca aatattgatc
     2041 tagagtggaa agttcttttt ccatatgcta aaatctcctt atgatgtgtt ttctttgtga
     2101 ctctttgctt gccggcggag tcactttttt atttgttgcc atgctttttg cttgtcaata
     2161 tgttgttggc ttaggatgat tggtttatag tatttccacc agcaattagc aattgccgtc
     2221 cctattctta gcgcttcagc tctattcatt gtcatcacca aaaagtctct gttgtctgtt
     2281 cagttgatca atttccatac ggatcgcagt ttctggcaac cacatttcaa taaatgaaac
     2341 agcatcatcg aatctcttac gaggtaactc gccatatctt gggattgaaa aggtacgttt
     2401 aaattcagac caaaattttg agaatacttt tttgctgatt tcttcataag ctcggctttc
     2461 ttttccccct agaactccca taactttcat atttcctttt tgcttaattt caaactcttg
     2521 ttgtccgcta attcgcatag tatctttaag catggaaaca tcttttttaa catctttcat
     2581 ttcttctaat tgatagatca tcatatcttc aattgtttga ggaacagtat tcttgcgaat
     2641 aacatcttcc atttcgttga atgcttcaat gtatttttgt ttgaagtaga tagctttctt
     2701 tcctgtaaac cccatagcca gcaagaaaaa tccatctcta ctaatgaaga aaactcgtcg
     2761 atttctgcca tatgaatctg gttcattacc ttctacaaac atctgtccaa aattggacac
     2821 atcttttttt agtgcatcaa tatctcttaa aacatgttga tgttttttct cgaagctttc
     2881 tgccacttgt aagctcgtag tcacagcttc tttatttttc aaaattacta attcttgcat
     2941 tatttcttct ctcctttttg gtataattta gttaaaaact ggtggtgttt attttgaatt
     3001 tttttcactt aacaattttt caatggatgt caataataag ttttatattg agtacgtttt
     3061 taacagggat aaaaataaaa ggaatgcgcc ctcaactaga agttgaactt aatgcttctt
     3121 acttcgctgc agatatgatt tatacaaaag taatcatttc taactattca acagaaccag
     3181 ctatgttagt taatttagaa ctttcatccg ctaacttaaa ccgcagatgg tcagctactc
     3241 catttaagaa attaattgct aaaggaggat cagtcgatga taatagaata tactctgaag
     3301 ctgtaccgct aaatattcct cctaaaagtg ctatatcttg ttaccttgca tttgaagtag
     3361 ggaaaattaa ttttaataaa ctccttaatc accaaacaaa aatgatattt actctaaata
     3421 gaacccaaat ccacaaaatt gttgatatca aaaatacaaa cttcccaata gagaaattag
     3481 tgaaagaatt aaactgagta atagtaatat acattctagt ttctcttttc tattcatttt
     3541 tagtcagccc cctcggttgg ctttttcgct ctgtactcag cttcagcttc atcaagcccc
     3601 ataaaaatcc aaaccatgta aacaatcgtt cctatcaacg cttgcctgct tccccaaagt
     3661 cctaaagcgt agatgattag cggtgcgctg aacactagcg ctctattaaa ttttcccatc
     3721 cgcttgcctc cttaagattt ccgaaaaatt tgtttctaaa aattcaagtg ttttacttct
     3781 taaaaataga tatgtgtctc ttccttcaac tggataatag acaaatccat ttttgttttt
     3841 ctcgatatcg ataatatttc tatatcttgg gttctttaaa actctagaag taaaccaatc
     3901 atattttctg ttaatccgtt ctagcacttc tggcaacgtc atccatctac cagtatcatc
     3961 agcttttttt aactcctcat aatccacttg ggagataatt acatagcctt ctggaattgg
     4021 gatttttgct tctagatatt gcattagctg ttcctccctt tacaattcgt acatagtgat
     4081 aatcgaatct ataattctgt ttgcttctgc agaagtcttt ttaccgttta aaattaaaga
     4141 taagtagctt ttgctaattc caaatctttc agcaagcatg gtgtaagtta agaactttga
     4201 actttcgaca tattctttga ttttttctct atctcgttga gtgatttctg caatgtcagt
     4261 catactaaaa ctcctttcta accaatttcc tctaaatcca tttgagggta atatccttct
     4321 ttttttagta attcgtagat aaatagacgc cctttctgtg tccatttggt attcattaca
     4381 attttagtgc caccatcggc tttcgggatc tcagttgtat gagattttgt gtatccttgg
     4441 ttcatgtgtt ttttgcacaa taaccattgg ttaccgactt ttttctgaat acctagttta
     4501 tgaagtaatt tattcatctg ttgtggagac atcccataat ctgctgcaat ctgactaatt
     4561 gttactgaat ctgtagaaga taatatgcta tctaaatagg agattttagg ttcgtactct
     4621 gcaatctttt gttctgcgat taatcttcca gttctttctt cttttagttg agttgctaat
     4681 tgaatgattg tatctggatt aagcaaagct tcttctactt tttctggagt tagataacct
     4741 ccatgttttc taattgctgg caacacttca cttgttaccc aacgtttaaa ttttttggca
     4801 gagggaagtt ttgattttaa gattaaactg tacaaaccag attcgttgat gattgtcatc
     4861 tctcttgatt gacctgaggt cgtgattcgc gaccccatct tatcttccaa atctacatgc
     4921 cgcgacaaag catctttagt gtttgaataa cccaaaacac tcgcaacgtc tttgcctaca
     4981 aaatatggtt catcatttac taaaattgtc cgaacttcgt tttgttcgaa attaaaaatt
     5041 tgcggtgtgt tcatatttct cattcctttc ttttatattc gtaaacaaat ttaacaactt
     5101 ttttctaaat tcaattgaca gtatctgagt aatactctat actaagagca taattaaata
     5161 agacataaaa acattgattt taaagctttc ttggcggtct gcatttacat atcaatagtg
     5221 ttttttgttg tctttttagt tgttaaatct gtttacaaga tatagtatag ctcattactc
     5281 agaattagtc aaattatttc tgcgtatttt tctaaacttt ttttgtaaac atttagaaag
     5341 gttgttttat cgatgaatac ctatgaaata ataaaagact tggcgaagag gaaaaagata
     5401 tctatacggc agttagaaat taattttgga tattctaacg gttatctagc aaagtggaaa
     5461 aataatactc ctaattcaga tgaattaagt cggattgctg actatttcga tgtctctgta
     5521 gactaccttc taggtagaga agaaagagaa acccctaaac atgtggattt atcagaagac
     5581 gatactgttt tttcttttga tggaaaagaa atatctaagg agacaatgcg taaagcgatt
     5641 gcaattgcta aagctttaga ggaaaatgaa tagttggagt gatggtttgt atgtatttga
     5701 aattgaaaga aatgttgagc gaatacaatt tgaaagtagt ttatatggag atgaaagagc
     5761 ctggtttcta ctatccaaaa cccagaatca tttttttgaa tgaaaatcta tacggtgaaa
     5821 ctgcagaagc ctttcattta tctcatgaac ttgcacattt cagcgcctct cattttgaat
     5881 tttcagtttt gtacgatact tctacaactt ttcactcaaa atttgaaaca gaagcagata
     5941 aaatagctat tctaatttta ttaaatatct atattgagaa cgaactgact gatgaatctc
     6001 agtttaatct cgaaaaattt atggagtatt attctattca gaataagctc agatacactt
     6061 gttatgctgt ctgccaatgc tattttaaga aaaaatattc ttacgcaagg caatatgtat
     6121 gaatacatca agaattatta aaaaaaccga tttcagcaaa acattaaaaa agcccgtgct
     6181 gcaacacggg ctctttcctc atatatgagc ttctacaaaa aaaatcatat cacagaaatg
     6241 aggaagaaaa aatggaaaaa gagattttaa taaaatctcc aggaaaaacc ttgattaaag
     6301 taactgatga ttctatttca attattagaa aaggatttat aaatttagtt aatcaaggta
     6361 ttaaaggaga aaaaactatc ccctttaaaa atatatcagc cgtacaatta aaaaaaccag
     6421 gtatgagtaa tggttatata caatttacct tgctaggcgg aaacgaaagt cgcggaggta
     6481 tattagcggc cacgaaagat gaaaacaccg ttatgtttac aaaaaaatat tggaatgaaa
     6541 tggaaaattt aaaaaaatat atagagaagc aacaatctat attagataat aattccaaag
     6601 aaacacaaat ttcaagtgca gatgaaatta aaaagtataa agagttgtta gatgaaggga
     6661 ttattaatca agaagaattc gattttaaga aaaaagaatt gcttggttta taatattcaa
     6721 tatcaaaaga gaaagaggat ctattaatgg acggtatatt tggttttact ggtattgttt
     6781 tatttattat aggtttaatc atgttaattg taagatttat caaaaaaaca aataagaaaa
     6841 cacctatgat tctccttatt atcgggatta tttttactac cgtaggtttc tcgctttcct
     6901 catcaaacga ggcaaatgac aataacaaac aggaaagctc atcatctgat actcaaacta
     6961 ctacatctaa cagcagcaat aaaagcctaa ctcaatttga agaattttta gagacaaata
     7021 atcatgactg gggtgctttc ttagatagtt attattctat tactccagct actgagcaaa
     7081 atacagcttt tactaaatat attagtggta aaacatatac ttttgaagga actgttatcg
     7141 aatcaatgac tactagaata gccattatag cagacaaaga gtacgatgat aaaagttgga
     7201 atgatatttc tgcaacacct aaagtttcat atgtaatttt tgcgaaggac ttaaacaatg
     7261 ctgatacctt tacaaagggc gataaagtaa cttttacagg agaaattagt tcaagaggat
     7321 cgaacataga aaaatcctat gctcaatggg atatgattaa tagtaaagta agtaaaaaat
     7381 aaatgaacca cgccccacta agagttagat tgtgcacaat aataaaacct atacaaaaga
     7441 gtgccatcag gagtcacaat gcttgtaaag gaaatgacaa aataggaggt aactatggat
     7501 aatagcaatg aaaaactaac caaaaaagaa tatcttgaat taatagttga aggcggtatt
     7561 ggagcaattc cttatattgg tggcgttgtg cagtcacttt attttgggtc taaaaacgag
     7621 aagcgtttca aacgcatcga gaaattctac aaaaatttaa acgaatcatt agaaaacatt
     7681 cgcgatcaaa ttccagaaga tgttttcaac ttagagaaca aggaccaact cattggaata
     7741 ttcgaaggga taaatgacga ggtagaaaaa tcaaaggcac aaaataaaat agatatgtat
     7801 aaaaatcttt ataagaattg tttacttcga attaacagcg cttcatggga taacgaggag
     7861 tattatcttc ttgtactgaa tcaattaaca tcgattgaga ttcaattgtt agcatgctta
     7921 atgagtcgtg gaaacgaaaa tttcactgga aatatcagca tgtctggcta ttcacaagag
     7981 ctaatagatg gtagcttaaa tagattatct gattttggtc tgttagaaaa aacgattagc
     8041 tccatagtat taggtgatgt cggcaaacaa aatatgggct acaaaatatc tcatttagga
     8101 attcaattta ttaactcaac tcttacttaa gttttctttc taatatgaca tctagaccta
     8161 tcagcaatgc aacaataaaa aaccagacat accaataatc aacaaataat ctaaactctg
     8221 gaagttcagt tattctttta aaaatcactt taatcataat aaacacctct gattggatga
     8281 tctaatacac atccaattat accattaaaa cgacaaatag cacatccttg cgccggcaag
     8341 caaaaaggat gtgcaaaaaa taataaaacc caaacaatgg gcttctttat agttcctatt
     8401 gtatcagaga aagagagctg attcaattat ggcaagatta gtcaaacgtg gaaatagttg
     8461 gcaatacgaa atttcataca aaaaagatga cggaaaatac acgaagataa gaaaatcagg
     8521 atttaagaca aaaggagaag caaaagatgc cgccaacgaa ttagaatata acttgaacaa
     8581 aggccttaaa ggggatcgca aaaatctatt attatcagat tactttgagg attggatgca
     8641 actttataaa gaaggaacag tatctcctat cacttataga aaatacgaag atacgttaat
     8701 gaacataaag aaatatatgc cagcggtatt gatttctgat ttagatagag tgggatatca
     8761 acgcttttta aataagtatg ctaaagacca tgtaaaatct accgttatta agtttaataa
     8821 ccatattaga gcgtcgttga aagatgccgt agaagaagga ttaattccgt ttgatccaac
     8881 tagaaaagca gtaatcaaag gaaaagattc attgaagcca aaagaagata aatatttaga
     8941 ttatgatcaa tttaaatctt taatgaaact cgtagaagaa aacctttctg cgcagtactc
     9001 ttctcctatg ctcgtgttag ttgctggtgc cactggaatg cgatttgctg aacttctagg
     9061 attaacatgg gaagatatcg atttcgaaga tcaaatcatc actattaata aaacatggaa
     9121 ttataaatta aatgaatggg gaaaaacaaa aaacgaaact tcaaatagga aaatttccat
     9181 tgataaacat acgattgatc tcttaaaaaa gtttaaaatc aatcaaaaag aattattcga
     9241 gaattttgaa atcaaaaacc ctcataattt tgtttttttc aacttaaaaa atggattagt
     9301 ttcatcaaac gccgtcagca aatatttgcg caaaaaatta aaagaattag ggattgaaaa
     9361 gcaatttact ttgcatggac taaggcatac acatgcatct attttacttt atcaaggagt
     9421 aaatatactt agcgtatcga aacgtttagg acatagcagt ttagaaacta caatgtctac
     9481 ttatacaaaa taaccccctg taccgcaaag gatacagggg ttatttgtac gttcctgact
     9541 aactattaca cgtcttctgt tgtgtttgtt attataagaa atgttatcat aataggattt
     9601 ctttttgttt gtgttttatt aaattcgatt ttttttggca cataatttgg cacaagtact
     9661 tgttcaccta tttatttagt ataataaatt ccacctttac aaaaagaacg tttgttcgta
     9721 tactcttttc gaggtgatct ttatgatgga agaatttatt agaaaaaata ttagtgatga
     9781 atatgcagat ttttatgagc aaagcaacga aaaagacaaa ttccagatgg atgtttcaat
     9841 tttagctata ttagcttttt ccgaaaataa acaacctgta actgcaaaaa aagaaacagt
     9901 attctctgaa ggcaaaataa aaactcgata tatattagag gtagagacta agtttaaaaa
     9961 tagatcggag taatggttat gctttttaat gagacgcaat tatggtttaa atttgatcct
    10021 tcgaatagat ttgtcaaaga tttttataag gtgtgggatt cagaagtttt ctttttagca
    10081 atcgaagata gcttattaat taatctctac tattctaata agaactactt taaaatccct
    10141 gctgcgaaaa ctagaatgaa gaaagacgta tattttttgt ttgatatcgt gactgatgtg
    10201 ctagacgctc gaagcgatca tcggcgttat gactatataa agtatacttt cgttgatcca
    10261 gaaagataca aagattaaag taggctacct aaaaaggtag cccggaacgg attttatcac
    10321 catacttatg aaaggagata ttttttaagt tagtattaag attgtgtaat atgatgatat
    10381 ctatatttta tagtatcagt gctataaaat caaaaataag tcactaatta actaccactc
    10441 caattataag ccttttttct cacttttttt caaaaatatg gtatgctttt taatggcttc
    10501 aaatataaaa gagtttaaag cgtaacacac ttatggggca gtggtttttg gggaacgctt
    10561 taaactcttc tttattatta tctcacaat
//
LOCUS       DAFBSV010000093        10405 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.094, whole genome shotgun sequence.
ACCESSION   DAFBSV010000093 DAFBSV010000000
VERSION     DAFBSV010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10405
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.094"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            81..722
                     /locus_tag="LLB18_002369"
     CDS             81..722
                     /locus_tag="LLB18_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBK5245347.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            741..1376
                     /locus_tag="LLB18_002370"
     CDS             741..1376
                     /locus_tag="LLB18_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBK5245348.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            1394..2209
                     /locus_tag="LLB18_002371"
     CDS             1394..2209
                     /locus_tag="LLB18_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK5245349.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            2528..3964
                     /locus_tag="LLB18_002372"
     CDS             2528..3964
                     /locus_tag="LLB18_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBK5245350.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            4153..6585
                     /locus_tag="LLB18_002373"
     CDS             4153..6585
                     /locus_tag="LLB18_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBK5245351.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQLSFVPI
                     DSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQDYELPT
                     VDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEVQPAVG
                     VKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIEAQPNH
                     PDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRAKPHEV
                     KLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAATGVRNI
                     SGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMARAAGI
                     HMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGDMLFLP
                     MGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQPQDELF
                     EEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKVFIEQE
                     ETSETLPDDNDM"
     gene            6815..7882
                     /gene="rlmN"
                     /locus_tag="LLB18_002374"
     CDS             6815..7882
                     /gene="rlmN"
                     /locus_tag="LLB18_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBK5245352.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(8075..9178)
                     /locus_tag="LLB18_002375"
     CDS             complement(8075..9178)
                     /locus_tag="LLB18_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBK5245353.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            9731..10279
                     /gene="aac(6')"
                     /locus_tag="LLB18_002376"
     CDS             9731..10279
                     /gene="aac(6')"
                     /locus_tag="LLB18_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBK5245354.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         3476 a         1771 c         2247 g         2911 t
ORIGIN      
        1 aaacagaggt ggaaccacgt ataatacgtc ctcttggcat ttgccaagag gattttttta
       61 ttttaaagga ggaaaagaag atggagtatt tgattgaagt tatgccgcaa ttattagtag
      121 gagcactcac aacattgaaa ttatttttat ttaccttgat tggctcatta ccattaggga
      181 ttgttttagc attaggattg tctttgcatt ttaagccgct acgctacttg cttcaaacat
      241 atgtatgggt tatgcgggga acaccgctgt tgttgcaact gatttttatt ttttatgggt
      301 tgccgacgat tgggatcgtt tttgatcgtt tcgaagcagc actcattgcc tttatcttaa
      361 actatgcagc ttattttgca gagatctttc gtggagggat acaatcgatt cctcaaggtc
      421 aatatgaagc agcgcaagtt ttgcaattaa gtccctttca aacggtgacg aaaatcgtca
      481 tcccacaagt gacaaagatt gttttacctt ctgtagggaa tgaagttatc aacttggtca
      541 aagattcttc cttgatctat atattaggtt taggtgacgt aatgcgtgct gggaaaatcg
      601 cgatggaacg cgacgcgact ttactgcctt tgctaggcgt ggcaatcatc tatcttacat
      661 tgactggtat tctaacaatc gtaatgaaac aagttgaagg aaaattaaat tattaccgct
      721 aactgatagg aggaagaaat atgattgaat tgaagaaagt gaacaaagca tttggtgaaa
      781 aaaaaataat caaagatttg aatctaatca ttccagatgg gaaaacatta gctatcgtag
      841 gtccttccgg tggcggtaaa accacgcttt tacgtatctt ggctggctta gaaagttctg
      901 acagcggaga attttattta gacggtgtac cgttcaaccc attcgagctt aaaatgaaag
      961 aacaagttgt aggagtcgta ttccaagact tccagctatt tccacatctg aatatttttg
     1021 aaaacattac cttagcacca aaaatggtat tgaaacagac aaaagaagaa tacaccaaaa
     1081 aagcagaaga attagcggct tcattaggga ttagtgattt attgaatatc tatccttatc
     1141 agctttctgg cggacaaaaa cagcgggtag cgattgccag agcattggct atgaatccac
     1201 gggtattggc ttatgatgaa ccaacaagtg ctttagatcc tgaattacgc cagcaagtcg
     1261 agcgtttgat cctatcattg aaagaagatg gggtaaccca aattattgtc acccatgatt
     1321 tagtatttgc agaaaatgtc ggtgatcaat tactaaaagt ttccccaatt cattaagaaa
     1381 ggagaagata gagatgaaaa aaaccagttt tctattcgct ttgatcgcag gtcttcttct
     1441 ttttgcaggc tgttcgaaca aaaaaacttc agcagataat tgggcgacta tcaacgaaga
     1501 gaaaaaaatc gttataggtt tagacgatac atttgttcct atgggattta gagataaaga
     1561 cgggaagctc acaggatttg atattgattt agccaaagca gtctttgaac aatatgggat
     1621 tacggtagac tttcagccca ttgactggtc aatgaaggaa tttgaactga acaatggaac
     1681 gatcgatttg atatggaacg gctattccaa aacgccggca agagaaaaga aagtgcaatt
     1741 tacaaaacct tatatggaaa acgatcaagt gctgatcaca cctaaagaat caggaatcac
     1801 aaactttgga caaatgaata ataagagatt aggtgcgcaa aatgggtcat ctggttatga
     1861 tgtatttacg aaacaaccag aagtattaaa agagatagtc aaaaaccaag atgctgtttt
     1921 gtatgatagt tttaatgaag cattgatcga tctgaaaagc agacgggtcg atggtctgct
     1981 gatggataaa gtatacgcag actattattt gaaacaaaga aacgaactag aagacttcaa
     2041 cataacaaaa ggttcttatg agagtgagga ttttgcagtt ggtgcacgca agtcagatag
     2101 tacattagtg aaaaaaatca atgaagccct agatcaacta gagaaaacag gtgaattcca
     2161 aaaaatatcc gataaatggt ttggcgaaga tgttacgccg agaaattaac aaatagggga
     2221 ctgtgacaaa agacgtgtca cagtcccttt ttccgaataa acagtgttct cctgccaact
     2281 ccttgtgact cggagctgaa tggcaggctc acaacctctt ggtaaacggt gttcaaaagc
     2341 cagtttttcg gtattaagcc aaatttatgc aaaaatgtag aaagccattt tcacaaaatt
     2401 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacatat ttttattttg
     2461 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
     2521 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
     2581 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
     2641 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
     2701 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
     2761 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
     2821 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
     2881 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
     2941 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
     3001 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
     3061 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
     3121 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
     3181 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
     3241 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
     3301 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
     3361 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     3421 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     3481 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     3541 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     3601 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     3661 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     3721 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     3781 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     3841 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     3901 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     3961 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     4021 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     4081 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     4141 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     4201 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     4261 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     4321 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     4381 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     4441 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     4501 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     4561 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     4621 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     4681 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     4741 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     4801 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     4861 gcaaaagaag ctgcagaata tgagaagaaa aaagcggtga gccagcaaag ggaaaatact
     4921 gctgatgaat ggcaggaacc agaaaataca gagccggagc agctaagttt tgttccaatc
     4981 gacagttttc aagaaaatat ccatcctgcg aatctagaga aaccagtacc agatacacca
     5041 aaacagacca atacagcaga aggtttttca gatgagttgc cagaggatga cggtacctca
     5101 ttagaatttg agattgaagc agaacaggaa aatcaagact atgaattacc gacagttgat
     5161 ttgcttgatt ctataccaac tgtggatcaa agtgatgagt ataaaaaaat tgaaaaaaat
     5221 atcggcgtat tagaacaaac tttccaaagt ttcggtgtcg atgccaaggt cgtcaaagcc
     5281 agcttaggac catccgtcac aaaattcgaa gtccagccgg ctgtaggggt aaaagtaagt
     5341 aaaattgtga acttaacaga tgatatcgcg cttgctttag cggcgaaaga tgtccggatg
     5401 gaagcaccga ttccaggtaa atcactgatt ggtattgaag taccaaatgg aaagatcagt
     5461 atggtttcct ttagagaaat catcgaagca caaccaaacc acccagataa attactagaa
     5521 gtacctttag gacgtgatgt ttctggacgg gtacaaacgg ctgatctttc gaagatgcct
     5581 cacttactcg tggctggttc gactggtagt gggaagtcag tagcaattaa tgggattatc
     5641 acaagtatat taatgcgtgc taagccccat gaagtaaaac tgatgatgat cgatccgaaa
     5701 atggttgaat tgaatatgta caacggcata cctcatctgt tgacgccggt cgtgacgaac
     5761 cctagaaaag cagcgcaagc cttacaaaaa gtagtacaag aaatggaaga acgatatgaa
     5821 aaattcgcgg caaccggagt aagaaatatt tctggttaca atgaatttgt tcaacagaaa
     5881 aacttggaaa acggaacgaa acatccaacc ttaccattca tcgtagtgat cgtagatgaa
     5941 ttagctgatt tgatgatggt agccagcaat gaagttgaag atgcgattat tcgtttagcg
     6001 caaatggctc gggcagcggg gattcatatg atcctagcta ctcaacgtcc aagtgtggat
     6061 gttatcacag gaatcatcaa agcaaatgta ccttccagaa tggcatttgc ggtatcaagc
     6121 ggtacagatt ctcggacgat cattgattct aatggggcag aaaagctctt agggcgagga
     6181 gatatgctat tcttgccaat gggtgagaat aaaccgatcc gtgtgcaagg agcattcatt
     6241 tctgaccacg aagtagaacg ggtcgttcaa tttgttacag atcagcaaga agctcattat
     6301 gaagagaaaa tgatgccgac agatgaagtt gaaacgacag gtgctccaga acagccacaa
     6361 gatgagctgt ttgaagaagc aaaagcactt gtcgttgaaa tgcaaacggc aagtatttcc
     6421 cttctccaaa gaagatttcg gatcggttac aaccgagcag cacgtttagt agatgaactg
     6481 gaagctcatg gagttgttgg cccgtcagaa ggaagcaagc ctcggaaagt attcattgag
     6541 caggaagaaa catcagaaac gttgccggac gataatgaca tgtaaaactt gtgtgatgaa
     6601 gggttgaaaa acgaataacc aataaaaaga caaggcatga tgataccaaa agaaaaaatg
     6661 gtttttttcc atcttttcta atacggtatg atgtcttgtc tttttagttt ttgtgagatt
     6721 aaagttctat tcgatttatt tgtgaagtat tgcattaagg aaatgaatca tgtatagtat
     6781 gtagcgaaac tttgagaaaa agagggaaaa tactttggaa aaacagtcca tttatggctt
     6841 gacgaatgaa gaattaatca attggtttat agaaaacggc gagaaaaaat tccgagctgc
     6901 ccaagtttgg gaatggttgt atcaaaaacg tgtaagtaat ttcacagaaa tgacgaatct
     6961 atcgaaacaa ttgatcgaaa aattatcgga gcattttatc atcaatcctc taaaacagat
     7021 ggtcgtccaa gaagcttcgg atggtacagt aaaatatttg tttgaactcc ctgataaaaa
     7081 catgattgag actgtactga tgagacaaga atatggcttg tcagtttgtg tgacgacaca
     7141 agtaggatgt aatatcggct gtacgttttg tgcaagcggg ctgctcaaaa agaaccgtga
     7201 tctgactgct ggagaaattg ttgcacagat catgatggtc caacattatt ttgatgagcg
     7261 caatcttggc gaacgcgttt cacatgtcgt tgtaatgggg atcggtgagc catttgataa
     7321 ttacgacaat gtaatggact ttttgcatat catcaatgat gccaaaggat tggcaattgg
     7381 tgctcggcac attacagttt ccactagtgg attagcacac aaaatcaagg aattcgctaa
     7441 taacggcttg caagtcaatc tggctatttc cttgcacgcg ccgaataatg aggtgcgaac
     7501 atcgatcatg cggatcaacc gaagtttccc aattgagaaa ttgatggaag ctgtggatga
     7561 gtatttagag aaaacaaacc gtcgaatcac gtttgaatat atcatgttga atcaagtaaa
     7621 tgatagacca gagcatgcgc aacaattagc agatctatta aaagataaga aaaaattagc
     7681 atatgtcaac ttgattccat ataatccagt cagtgaacat gatcaatatt ctcgcagtcc
     7741 aaaagctgat gtattgagat tttatgatgt attgaagaaa aacggcgtaa actgtgtgat
     7801 acgtaaagaa catggtacag atattgatgc agcttgcgga caattgcgaa gcaagcaaat
     7861 gaaaaaaaca gttgccaaat aatcgtatcc tactcgtttt ttcaattacc ataaaaggag
     7921 cagttttctt aattaaggaa ctgttcaact taaataagag aaaagattct atagcgaaag
     7981 ctataaagct ttttttgaca agaaaaaccc tcatcaagca aagaaatgtc ctcaatttga
     8041 tgacagcctg cttgatgggg gttttagcaa ttatttaact gattttctta tatccttgct
     8101 ggctttcttg tgtagcatga taagtttcta cgtcaagaat ggcctgttta aatttttctc
     8161 gggtgatttc ataaggcaca tgtttaatat catttgttgc catggcttta tctaagattg
     8221 cttctaaatc ggtcgtgaca ttgagattca tgtcggttaa cgatactgga agttggttct
     8281 ttttcataaa cacatagatt ttatcaaaca aatcgaactg ctgatccatc atcaataagg
     8341 tcagtacacc ataactgaca gatgctccgt gaaggtatcc ctccattttt tctagaacag
     8401 tcgtaccgta atagaatgag tgtgccatag cagaattata gttattgtta actaaaacag
     8461 aaaccaatcc ggtagtaaca atgatatccg aaacgacttg ttcaattgca tatgagggac
     8521 gatcgtcggc actatctttc aatgcttgcg taccataagt caagagacga tcaatgcaca
     8581 tttttccgat ttggattcct aatctatccg tgtagcctag atcatcgcca cgagcagaaa
     8641 aagtagattc gacttctttg gataaagcat cgccaatacc tgcccataag tatttatcag
     8701 gtgcttcggc aataattgct gtatcaatga aggtgtgtac aggtggtttt gaaggaaaga
     8761 agagtccgtc cattacgcct tcttcgttat agatgacaca taccgcagtg acgggcgaac
     8821 agttcgaacc aatagtggga aaggtgaaga ctggtttagc tagtttttca ccaatgactt
     8881 ttacagtatc gcaagcacgg ccaccaccga ctgcaaacag gacgtctgct ttttggacac
     8941 tttcatgctg gatcaactgt tcaatatttc cataagttga attacccccg taccagagac
     9001 tggcgacaac ctctatttcc tgtgtcaaag ctacttttat tttgttttct gcctttgaaa
     9061 gtgcagtctt ccctccaatc agcactactt ttgtcccata ttctttgacg attccatttg
     9121 ctttttcata cgcatctgtt ccaatggtat aatttggtaa gaaaacactt tgactcatat
     9181 tcatttcctt ctttcttcgt tgaaacgggt taaaatttta aagagtgatc gatctgactg
     9241 cggctgtaga tggagtagag gtgaacctaa gacaggataa gtgatgaata aggtggcatg
     9301 aacaccttga aatcatcaat aagtatccta aaaacgaaca agtacaaaaa cattgaaaac
     9361 gacaataatg aatttttgtt cctcttagta tttctaccga ttccctttgc ttttttgtaa
     9421 ttatctaaaa attctaaaaa ttaagattat tatatgaaaa caggttttat ttgtcaattc
     9481 ataattggtt ttttttaaag caaaagataa tctatatcat gatgaacaaa cagagttttt
     9541 tcctccaatt gatggctttc ctgatctttc ctattttgaa taaagtgttt ctgtataatt
     9601 tttttatttt ataagtaaga taaataatga aagaatagag atactgattg gtagctaaag
     9661 atttttgagc gagaacattt cgttttttca aaaggactgt tagaataagc aagaacaagg
     9721 gggaagacgt atgataatca gtgaatttga ccgtaataat ccagtattga aagatcagct
     9781 ttctgattta ctgagactga cttggccgga agaatatgga gacagctcgg cagaagaagt
     9841 agaagaaatg atgaatccag aacgaatcgc ggtagcagcg gtagaccaag atgagttagt
     9901 aggatttatt ggtgcaatcc ctcaatacgg tatcacaggt tgggaattgc atccattagt
     9961 tgtagaaagc tcccgacgaa agaaccaaat aggtactcga ttagtcaatt acttagaaaa
    10021 agaagtagct tccagaggag gaatcacgat ttatttaggt acggatgatt tagaccatgg
    10081 aacaacgtta agtcaaacgg acctgtatga gcatacattt gataaagtgg cttccatcca
    10141 gaaccttcgt gaacatccgt atgaattcta tgaaaaatta ggttataaaa tcgtaggtgt
    10201 cttaccaaat gcaaatggct gggacaaacc ggatatttgg atggcaaaaa cgattattcc
    10261 tcgaccaaat tctcaataat aaaaagaggt tgtgacagaa gtaatcagct tcaagaaata
    10321 agaaggaatt tacgaaaatt acttcttgaa tttttgtgaa attccaactt atttccgaag
    10381 aagctacttt tggaacaccg tgtac
//
LOCUS       DAFBSV010000094         9835 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.095, whole genome shotgun sequence.
ACCESSION   DAFBSV010000094 DAFBSV010000000
VERSION     DAFBSV010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9835
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.095"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(<1..229)
                     /locus_tag="LLB18_002377"
     CDS             complement(<1..229)
                     /locus_tag="LLB18_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBK5245355.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEF"
     gene            complement(343..921)
                     /locus_tag="LLB18_002378"
     CDS             complement(343..921)
                     /locus_tag="LLB18_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK5245356.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(998..1528)
                     /locus_tag="LLB18_002379"
     CDS             complement(998..1528)
                     /locus_tag="LLB18_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBK5245357.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(1532..2392)
                     /gene="rlmB"
                     /locus_tag="LLB18_002380"
     CDS             complement(1532..2392)
                     /gene="rlmB"
                     /locus_tag="LLB18_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBK5245358.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(2385..2780)
                     /locus_tag="LLB18_002381"
     CDS             complement(2385..2780)
                     /locus_tag="LLB18_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBK5245359.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(2777..4189)
                     /locus_tag="LLB18_002382"
     CDS             complement(2777..4189)
                     /locus_tag="LLB18_002382"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBK5245360.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(4186..4722)
                     /gene="cysE"
                     /locus_tag="LLB18_002383"
     CDS             complement(4186..4722)
                     /gene="cysE"
                     /locus_tag="LLB18_002383"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBK5245361.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(4808..5047)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(5044..6504)
                     /locus_tag="LLB18_002384"
     CDS             complement(5044..6504)
                     /locus_tag="LLB18_002384"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBK5245362.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(6674..7831)
                     /locus_tag="LLB18_002385"
     CDS             complement(6674..7831)
                     /locus_tag="LLB18_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBK5245363.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(7865..9235)
                     /gene="radA"
                     /locus_tag="LLB18_002386"
     CDS             complement(7865..9235)
                     /gene="radA"
                     /locus_tag="LLB18_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBK5245364.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(9298..9825)
                     /locus_tag="LLB18_002387"
     CDS             complement(9298..9825)
                     /locus_tag="LLB18_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBK5245365.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         2500 a         2206 c         1778 g         3351 t
ORIGIN      
        1 aaaattcgat ctcaactgtc cgagtaagta catctgaata gctgtaagat actcgttcaa
       61 aagaattttc ttcaggatcc aaatcaacaa cgaatactga aggataggtt tctgttaaaa
      121 cgccgcggcg ttctgtttga cgctttcttc ctgtctgagc aaccaacatg attgggctgc
      181 cgatacgacc ttctaaatct ttcttgattg aagctaaagt tgttggcata cagttcacct
      241 ctactatcaa ctataccaca tatttttaaa attttcaagt ttaccataaa aaaaaagaaa
      301 tgcaataaaa ataaataaga agctcattaa gatttttcta aattattcct cattataaaa
      361 tttcaagtgt ttttttattt tgagttttac tctcccgtaa gcgctcatta cttgcttgtg
      421 atccattgct aaacattcag ccatgtctac aaaatcaacg ccttgcatat aataatgaaa
      481 aattttagct tctatttttg aaaactggat ttcgcaattt tcgattgctt cttttaataa
      541 aagatgctga atcgctaaag gttcttgcaa tgtgatctct gctaaaaagt ctggtccttc
      601 tgtctctatt ttttggtcga ttgagacttc atctttttga tcacgacgct tcagcgcgtt
      661 ctgcttcctc aacagagaat agatttgatt gcttataatg cttttataat aacttccaaa
      721 gctaacacct ttgctttttt cgtaagttct caatgcctga tataaagcga tccttgcttc
      781 ttgttcccaa tcctcagaaa cataatttct taaataatag gtgtttttca aacgtagtaa
      841 aagtggaaaa tatttttgat acagggcagc aaatgcttct tcgtcaccat tacgtgcagc
      901 gcgcaataac tcctcagaca taaaataatt cctccataaa ttcgtttatg gaggaatctt
      961 atcatcaatg attcatcgaa ctgattagaa cgatatgtta tttatttttt ctcattaaat
     1021 cgtccaattt ttgggacaat ttttttaact gctcttcatt ccatggagaa ttacgtcgga
     1081 aatcaataaa atgcatatct ttattttctt gggctattgt tttttccgtt ttttttatcg
     1141 tcttatataa ttcataagca gaagttcgta atgctccttg ggaaaagatc atccactgtt
     1201 ctgctaaatc gcttgtcgcc actgtcactt gtgtcaaacg gtcattcagc tgaccagcga
     1261 ttctctcgat ataactgtca gccgtttcgt cttctttcgt aaaaacaaca tccaactggt
     1321 atttcttata attttgttgg atgcccggaa ctagttgggc atcgaagaca acgatgactt
     1381 ccattccttc atatttcgca taatttgata aacgatgtaa aagagcttct cttgcatccg
     1441 ccattttgtc ctgcttttta agctggacaa gttccggcca cgaaccaatc atgttgtagc
     1501 cgtctacaat caacagctgt tttttcatgg tctactcccc ctgacgttgg gaaaaagcct
     1561 gatacataag caaaccagca gcaacactgg catttaagct ctggacgtgc ccggtcatcg
     1621 ggatcgtcag caattcatcc atttcttttt tcaatcctgg actcattcct ttgccttcat
     1681 taccaatgac taaagcaatt gatcctttgg cattccattt ttggaagttt gtgccggtca
     1741 tatctgtgcc aaatacccaa aatcctgttt ctttgagctg ttgcacagct tgtaccaaat
     1801 tcgtcacgcg tgcaacaggg acatgttcga ctgccccagt ggaagtcttt gttacgatag
     1861 gtgtgattcc aactgctcgg tgttttggta tgatcacacc atcgacgcca cttgcgtctg
     1921 ctgtccgtaa aatcgaccca aaattgtgtg gatcttcgat gctatccaaa atcaaaaaga
     1981 aggggtcttc ttttttctct tttgttcgtt caatcagttg gtcaagggat aaatattcat
     2041 aaggtgtaat cgcaagaacg actccttgat gcacgccgtg atcgctcaaa gtttctaatt
     2101 tttgtttagg aacccatttg actggcacag cttgttcacg tgcgatttct ttcagttctt
     2161 ctactttttc tcctcgtgaa tcttcttgaa gaaagagttt attccctcgc ccttgttgta
     2221 gcgcttctac tgcggcatgg tgcccaaaga cgaaattatc ttctaatgct tcttcatttt
     2281 gatcagaaac tgactgattt cgtccagttt gctttttatt tgaatatcta ttttgttttt
     2341 tgtcttcaaa tccacgtttc gattgatgtt tgtttgttct ttctttaccc atttttttca
     2401 ccaactttct gaatacacca gcggatcaat tcttccatcc gctcggtttg ttttgtcaaa
     2461 tgcagatagc ccatgagcgc ttcgaaccct gttgcgaccc gatacgtcgt aacatcagca
     2521 ttttttgcgc tcgtatggct tttagcattt cttcctctgc gataataaag ttcttcttct
     2581 tctgtcaaaa gatgttcttc cagcatttgc tgaatcaaaa aggcttgtgc attcgcagaa
     2641 acataattcg ttgccgcacg atgcagctta ttgggttttg tttctccttg atcaatcagg
     2701 tggtcacgaa catagatttc gtaaatcgca tctccaacat aagccaaggc taaaccgttc
     2761 aattgtgtgt aatctctcat gcttctcttc tccatcgggt tccttgcggt gtatcttcta
     2821 ataagatccc tttttctttc aacaaatcac gaatttcgtc gcttcggaca aaatcacgat
     2881 tgcttcttgc ttgatttcgt tcttcgatca attgttcaat ctcttcatct aataactctt
     2941 ctgctgtaaa taaaataccg aagatcgaaa gccattgcga gaataaagct tctccttgtg
     3001 ccaagacagc ggcagaaact ttcggctggt ctagataagt gttcagccac ttagcaagct
     3061 catagaccac tgtgatccca tttgctgcat taaaatcatc gtccatttct tcgatgaatc
     3121 gctgttctaa attttctaac aaagcgattt tatccgcatc atctgccaaa ttctctgagg
     3181 cagtttcttg gcggaatttc aaattgtcaa acgtattctt cagtcgttgt aaattggtgg
     3241 ctgcttcttt catcgtcgtt tcactgtagc ggatcggacg acggtattgt gtggtcgcca
     3301 tgaagaaacg caagacttgt ggatcaacgt ttttgatcat ttcatgtaca gtgatgaaat
     3361 tccctagaga tttactcatt ttttcatcgt cttcgccaat cgttacatag ccattgtgca
     3421 tccagtaatt agcgaatttt ttccctgttt tcgcttcact ttgtgcgatt tcattttcat
     3481 gatgaggaaa ttctaaatct tgcccgccac catggatatc gatcgtttct cctaaatgtt
     3541 ttgttgccat aacggaacat tcaatatgcc aaccgggacg tcctttgccc catggtgaat
     3601 cccaagaaat ctcgccaggt tttgcttgtt tccataaagc gaaatctaat gggtcttctt
     3661 tttgctgctg ttcttcccct gtacgctgac ttgctccgac ttccagttca tcgatggatt
     3721 ggtcacttaa tttcccataa ttttcaaatt tacgggtacg gtaatacaca tcacctgaag
     3781 attcataagc atagcctttt tcaaccaaca cttgaataaa tgctaaaata tctggcatat
     3841 gatccatgac tcttggatgc agtgtagcag gctcgacatt caacgctttc gtatcttctt
     3901 caaatgctcg gatgaaacga tcagcaactt ctggtgctgt aatacctaat tcgtttgctg
     3961 tacggatgat tttatcgtct acatccgtga aattcgatac gaaatcgact ttatagcctc
     4021 gatattcaaa atagcgtcga attgtatcga aagcaatggt gctacgagca tttccgatat
     4081 ggatataatt atacacagtc ggtccgcaga catacatacc gacatgtccc ttttgtatag
     4141 ggatgaattc ttcttttttt ctggtcaatg tattgtagat ttttatcatt ctgatctcct
     4201 cactttttct cctttgattc gaacgacttt tgctggtact cctaccgctg tagcgtcgtc
     4261 tggaacatct ttcaacacaa cggcacctgc accgattttg gcgttttttc cgatcgttac
     4321 cggtcctaat atctgcgcat tcgcagagag catggctcct tgtttaacag ttgggtgtct
     4381 tttacccgtt tcttttcctg tgccgcctaa tgttacgcca tggaataaaa tcacatcgtc
     4441 ctcgatttct gcggtttcgc caatgacgat tcccattcca tggtcgatga acacgccagt
     4501 tccaatcgtt gctcctggat ggatctcaac accagttagg aaacgccaga attgagcatt
     4561 gatcttcgcc aataaaaaga gccggtgctg atataaaaaa tgagagaaac gatgccaaaa
     4621 caaggcatga aaaccagggt atgtcaaaac gatctcagct gtcgaacgtg cagccggatc
     4681 gtttctcttt gctgcatcaa tcgctcgggt aaaccaactc atgactttcc actcctttcg
     4741 taagaatttt atgtaggaaa tcatcttctt ataaagaaaa gaagcgcctt ttaaataagt
     4801 ttccttatca aaagacgctt tccgcgtggt tccacttttc ttcataatca atgattatct
     4861 ctgacagcta acgcctgtta tacgttcttg gctactttgt ttcctataaa acagtttttc
     4921 ctgttttctg tgtttcgcca agaccactcc cagaggcatt tcggcaacca ttcattgata
     4981 ccttgcacca cccggtatct ctcttgtaat gatcagctgc ttactttttt ctgttcatcg
     5041 tgtttagttc agtacttgat ttaaatgtgc taatgatttt tcacgaccaa gcaattcgat
     5101 cgtttcaggc aattctggac catgcatttg tcctgataca gctacacgga ttggcatgaa
     5161 aagatttttt ccttttacgc cagtttcttt ttgaacagct ttgatggcag ctttgacagt
     5221 tggagcatct actacttcca tttgttctag ctgtgctttg aatgcgtgga gaacagtagg
     5281 aactgtttca ccagcaagta cttcttttgc tgcttcattc aatacaggat gttcattgaa
     5341 aaatagcgta gacagatcaa cgatttctgc agcatagctc atttgaggtt gatacaggct
     5401 aacgatcttc ttcacccatt cgattgtctt ttcatctggg ttttctgcta cacgtccatc
     5461 agcgattaga taaggcagac acatgtcagt aaatgcatct agatccattg ctttgatgta
     5521 atggttgttt acccattgca gttttttcgc atcgaaagct gcgggtgatt tacttaggcg
     5581 ttttggatcg aacattttga tcaattcttg gtgttcgaag atttcgtctt cgcccacagg
     5641 tgaccagccc aataatgcaa taaagttgaa cattgcatct ggtagatagc ctaattcgcg
     5701 atattgttcg ataaattgca agattgattc gtcacgtttg cttagttttt tacctgtttc
     5761 actgttgatg atcaatgtca tatgtccgaa ggttggtggt gtccagccaa atgcttcata
     5821 gatcatcagt tgttttggtg tattggcaat atggtcatct ccacgtaaaa cgtgagtgat
     5881 tttcatcaaa tgatcatcga ccgcaacagc aaaattataa gttggcatac catcgcgttt
     5941 ttgtatgaca aagtcgccac cgatattatc ggattcgaac gaaatagcgc ctttcaccat
     6001 atctgtaaat gcgtattctg tattgcgagg cacacggaaa cgtacaacag attctagacc
     6061 ttgtgcttct ttttctgctt gttcttcagg tgtcaagttc gcacatgttc ctgcgtaatg
     6121 aggcatttct cctcttgcgc gttgtgcttc ccgttctgct tctaattctt cttctgtgca
     6181 atagcatttg tatgctcgat tgctagcaag cagctgatca atcagcggtt gatagatttc
     6241 tttacgttca gattgacggt aagggccgta ttctccagga ttttcaggag attcatccca
     6301 attcattccc aaccaagcaa ggttttccaa ctggcttttt tcgccatctt cgatattacg
     6361 tttttggtca gtatcctcaa tacgaataat aaagtctcca tcattgtggc gggcaaacaa
     6421 ataattgaat aatgcagttc ttgcatttcc aatatgcagg tgcccagttg gacttggtgc
     6481 atagcgtacg cgtactttcg tcattttctt cctcttcttt caaactagac tttgactaac
     6541 agcaaaaatt ccgtcagtta cggcttctca aatatcattt atttaaagcc actcagcaca
     6601 aattttacct tttctaaggt aaatagtaaa gccaactggt tgaatttcct taccagttgg
     6661 ctgaatttct tttttatttt gattgtttag tctttttctc tgtctctttt ttattgtcga
     6721 ttcctcgtcc tgcatgtgca ggtttagcaa agatcatgcg tccagcagct gtttgaaggg
     6781 cacttgttac aacgacttcg atacgttcat tcatgtaatg ctgtccatct tctacgacaa
     6841 ccatcgtgcc gtcatcaagg taggctactc cttgttggcg ttctgtcccg gcttttacta
     6901 ctagaacatt catcgtttca ccagggatga cgactggttt tacggcattt gccaacgcat
     6961 tgatattaag aacaggtaca ttttggaatt cagagacttt attcaagtta tagtcattgg
     7021 ttacaatgac accatctaaa agcttagcca atttgatcaa tttgctgtct acttcactga
     7081 tatcttcaaa gtctccatcg tacatttcga cagatatacc ctcttctttt tgcaaggcat
     7141 ttaggatatc taatccgcga cgaccacgca cacgtttcaa actatcccct gagtccgcga
     7201 tgtattgtag ttcgtaaaga acaaaattag ggatcatcaa ggttccttct aagaatccag
     7261 tctttgtaat atcataaatc cgaccgtcaa tgatcacgct tgtatccaag attttatatt
     7321 tatggaaatt ttctcctgat tttcgttcta acagttgact ctcaacttga ctagctgttt
     7381 cttgctcgat ttttttgctt cgtgaaccaa aaactttctt ccattcttcg attcgtgtcg
     7441 ttcccattct caatcccaga tagcctaaga tgatcatcag taaaatcggc aatacactat
     7501 tgacgaatgg aatttccata ttgtaaagag gggtcgagat cacaacacct aaagtcaatc
     7561 cgatgatcgc accgatcgca ccgaagagaa gataagtcaa gctgacctca cttagttttt
     7621 gttctacttg tttgataata gctgagatat gtttggccaa cagcaaagat aataaaaaga
     7681 aaataagtgc gcctaacagg ctgttggtaa atgtattatt cagccatccg tttgactgtt
     7741 gaccgattgc ctgccaagct gagggtaaaa atgaaatacc caagcttgcg ccgacaatga
     7801 tcatcagcaa agtaatgaca cgtttttgca tcgtttttcc tccgtttcga caatcattta
     7861 ttagttagcg gaacacacgc ttcaacgttt cagccaaagt tgctactcca actatctcga
     7921 ttccttttgg cgcttcccag ttacctaagt tgtttttagg taggtatact tttgtgaagc
     7981 cgagtttttg gacttctttg actcgttgtt caatatgact gacacgtctg atttctccag
     8041 tcagtccaat ttcaccgatg aaacattccg ttggctgtgt tcctttttct ttatagcttg
     8101 aagcaatact gacagcgata gctaaatcaa tcgctggttc atttaatttt accccacctg
     8161 cagcttttaa gtaagcatct tgattctgaa gaagcaaccc agctcttttt tccagcactg
     8221 ccatgatcag agatacccga ttgaaatcaa gacctgttgt tgttcgtttg gcatttccga
     8281 acatagtagg tgtgactaat gcttggatct ctaccaaaat tggacgtgtc ccttccattg
     8341 ccacaacgat agcagagcca gttgcaccgt ctaggcgttc ttctaagaaa atctgtgaag
     8401 gattagcgac ttcttccaat ccatgctcat gcatttcaaa aatcccaatc tcattcgttg
     8461 agccaaatcg gttttttact gctcgcaaaa tccgaaaact atgatgttgt tcaccttcaa
     8521 aatataacac cgtatccacc atatgttcta acattcttgg gccggcgatc gagccttctt
     8581 tggtaacatg accgacgata aaaatggcta tcccatttgt tttagcgatt ttgagtagtt
     8641 ctgcagtggt ttctcttact tggctgacac ttcctgccac acttgtgatg tctggctgcg
     8701 tcatcgtttg gatggaatca atgataacat aatcagggga gatatgttcg atggcacgac
     8761 tgatttcgtt catatctgtt tcagcgtata gataaaattc tgtgttgata cttccgaggc
     8821 gttccgcgcg taattttatc tgctctgcgc tttcttcgcc ggatacatat aagacttttc
     8881 cgcctatggc tgctaattgc tgagaaactt gtaacagcaa agtggatttc ccgatacctg
     8941 gatcgccacc aatcaagacc atagaccctg gcaccacacc tccgcctaac acacggttca
     9001 gttcttctaa ttttgttttg atccgaggtt cttttttagg gacgacgtct gcgatttttg
     9061 ttggttttgc tttttctcct gtcaaacttg tccgagttct gcggtccgtt gtatcttgtt
     9121 cgatttcttc gaccatcgta ttccattttc cgcaatttgg gcagcgtccc aagaacttag
     9181 gcgacacata cccgcaattt tggcaaacaa attgtacttt tgattttttt gccattgtac
     9241 cgcctccttt tatcctaatc atgagacatt aaatcaagct taagtatctt taacgtttta
     9301 tttactggaa gaaccaaatc cgccttgacg ttgagcagtc gtttgatctt gatctgcttt
     9361 taaaaacggc aaaaagatcc cttggccgat acgctcgcct tttttgatca ctacatcctt
     9421 gaaaccaaag ttggtgaatt ggaacatgat atggccttca tttgcctcat tattgtaata
     9481 atcactgtca atcacaccta ctccgtttgt caacactaaa aaccgcttca acggattgct
     9541 tgaacggtta gcaagctgca aaaattcatc ttctcccatg taagctttga ttccagtagg
     9601 cacgagggtt ggtttcaatt gtttttcatt ttctgataca tcttttttca atccatctgc
     9661 gactgtttcc aacccctttt tccagcctgc tttccagata cttggaatca cgacctcttc
     9721 tgctgcttca aaatcatagc cagcagcatg atgtgtagcg cgctgcggta gattgatatt
     9781 ttgatcttta tatttagaaa taacttcaaa tcctcttttt ctcaccggtt ttcct
//
LOCUS       DAFBSV010000095         9828 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.096, whole genome shotgun sequence.
ACCESSION   DAFBSV010000095 DAFBSV010000000
VERSION     DAFBSV010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9828
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.096"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            259..744
                     /locus_tag="LLB18_002388"
     CDS             259..744
                     /locus_tag="LLB18_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HBK5245366.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            737..1420
                     /locus_tag="LLB18_002389"
     CDS             737..1420
                     /locus_tag="LLB18_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HBK5245367.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            1546..4191
                     /gene="polA"
                     /locus_tag="LLB18_002390"
     CDS             1546..4191
                     /gene="polA"
                     /locus_tag="LLB18_002390"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBK5245368.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELADKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            4236..5072
                     /gene="mutM"
                     /locus_tag="LLB18_002391"
     CDS             4236..5072
                     /gene="mutM"
                     /locus_tag="LLB18_002391"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HBK5245369.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            5036..5665
                     /locus_tag="LLB18_002392"
     CDS             5036..5665
                     /locus_tag="LLB18_002392"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBK5245370.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            5717..6049
                     /locus_tag="LLB18_002393"
     CDS             5717..6049
                     /locus_tag="LLB18_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBK5245371.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHISDEQKIEEQRMKH
                     YTGIEEKL"
     gene            6361..6852
                     /gene="nrdR"
                     /locus_tag="LLB18_002394"
     CDS             6361..6852
                     /gene="nrdR"
                     /locus_tag="LLB18_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBK5245372.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            6875..8248
                     /locus_tag="LLB18_002395"
     CDS             6875..8248
                     /locus_tag="LLB18_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBK5245373.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            8248..9174
                     /gene="dnaI"
                     /locus_tag="LLB18_002396"
     CDS             8248..9174
                     /gene="dnaI"
                     /locus_tag="LLB18_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HBK5245374.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            9303..9743
                     /locus_tag="LLB18_002397"
     CDS             9303..9743
                     /locus_tag="LLB18_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBK5245375.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
BASE COUNT         3388 a         1720 c         2161 g         2559 t
ORIGIN      
        1 aaaatcttgc caagccccct tttttgcaac ttatgataaa cggtgttcaa aagcttgcat
       61 ctgcggtaat aagcccaatc aaatcaaaaa catgagaagc tgttttttct tggctgttct
      121 tattatttga tgcaggacag ctttttcacg acctctgtaa actataggaa tctgttaaat
      181 caagggagca gaacttgcct tttacgctac ttttggtaca ataatgtatg attaaaaata
      241 aactggaggg tttctatctt gaacataggt aagccgagaa aactaggaaa aacaataaat
      301 gaaatcgagg aaggcgactc gttatcctta acagaatcta ttgaagataa ccagcttttg
      361 ctgtatttgg gattgacgaa tgatgcaaat cctttgtata tccaacatga ctttgcacaa
      421 aaaacagaat atcaacagcc aatcgttcca tcagtgatgc tgatggggat catcacaagt
      481 gcaatttcaa agcatcttcc tggaccagga tcacatgttg tcaatttttc tgtcaatttt
      541 attgaaccgg ttttccatta tgaaacactg acttttcagt ttgaggtcat aaaagtagat
      601 aagatgaagg atgtggtgac gatttctgta gaagcggaga atacgaacga agatcgtgtg
      661 ttggatgctg tcgttatggt ccaaccgcca caagttcctg aattggaaat agcaatcgaa
      721 agtgaaggtg aattgaatga ataatccaag tacatcaatg tcaggtatca atcgttttta
      781 tgcaaaagtt tatggatttt taggtatggg acttgccctt agtgcagtca cttcttactt
      841 ggctctttgg gtatttcctt tgcaattagc aacttttatc aataattttc cactaggctt
      901 tgtgggtctg tggatcgttg aactgatttt agtaatggtt ctaggcgtaa aagcacaaaa
      961 gaatccgagc ttagcaatcg gtggatttat tgcctactct cttttgaatg gcataacatt
     1021 agcggttact cttgcatact acgatattgg aacagtaacg caagctttct tgacagctac
     1081 tttgatgttc atggggatgt ctgttgtcgg agtaacaaca aaaagagatc ttagcggggt
     1141 tggaagagca ggacaggcag ctttaatcgg agtgatcatt gcactagtct tgaacatctt
     1201 cattttgaga agtagcgtag ttgagctgtt catctcccta ctgttagtcg tcatctttgc
     1261 agggattaca gcttatgata accaaagcat ccgtaatatc tatgtccaga caaacggaac
     1321 agcacatagt ggaattgctg tattcatggc attgaagctg tatttggact ttatcaactt
     1381 gttcttggcg tttctgagaa tctttggacg gaacaactaa aaaagaaaaa aattcatcag
     1441 ttggggctat accgaattat ttggtatggt cccgcttttt cttttcgcat tccgcaggat
     1501 tctttgttag aatgaataag aactttacag taaggagtta agaagatgac aaaaaataaa
     1561 ttattactcg ttgatgggaa cagtgtggct tttcgcgcat tctttgcgct tcacaattct
     1621 cttgaacgtt tcaaaaatag aaacggtctt catacaaatg caatctatgc attcaatacg
     1681 atgtttgaaa atgttatgca aaaagagcaa ccgactcatg ttctggttgc gttcgatgca
     1741 ggaaaaacga cttttcggac agaaatgtat gcggagtaca aaggtggaag atccaaaaca
     1801 cctggcgaat tcaaagaaca aatgccatat atacgtgatt tgttgacagg actaggggta
     1861 cagtattacg aattgcccaa ttatgaagca gatgatatta tcggtacttt ggcagaaaaa
     1921 gtagacaaag atcaatttga tgtcgtcgtg ctttcaggtg atcgggattt gactcaatta
     1981 gctagtaaag aagtaaaagt ggatatcact gtaaaaggtg tcagcgatat cgaaagctat
     2041 acaccagaac atgtagcgga aaaatatgat gggttgacgc caaaacagat tattgacatg
     2101 aagggactag ccggagatgc ctctgacaat atccccggtg tgactaaaat cggtgaaaaa
     2161 acagctatca agctattgaa acaatatggc tcagtcgaag gaatttatga acatatcgat
     2221 gaaatgaagc aaagcaaaat gaaagaaaat ctgataaatg acaaagagca ggctttctta
     2281 tcgaaaaaat tggcgaccat caatacttca gcgcctgtgg atgtctctat cgactcattg
     2341 aagtatgaag ggaaaaatct cgataaactc gttccgtttt ataaagaaat ggatttcaat
     2401 cagttccttt ctaaattgaa tatcgtagaa gaagaagtaa aaatggatga tattttgttt
     2461 gaagtcgttc atgaattcaa agaggaaatg tttactacgg atatggcgtt gtacgtggaa
     2521 atgatgggcg acaattatca tacagaggaa atcgtcggag tagcgtgggg gacagaaaag
     2581 aaaatttatg tcacgaacga tctatctgta ttcgaaaacc gagcgttcca ttcttggatc
     2641 actgatccga ctcggctgaa aaaagtatat gatgcgaaac gaacttatgt tgctttaaac
     2701 cgctatactg gaaaaacgaa aggaatcgat tttgatgtct tgctaggtgc ataccttctc
     2761 gatacgaatg aaaaaagcac agatatcgaa ggaatagctg ctcattacgg atacaacgat
     2821 atccaatcag atgaagctgt atacggcaaa ggggcgaaaa aaggtttacc agaagaagag
     2881 gaactctttt ttgctcattt agcgcgaaaa gtagctgcaa tcaatgcgtt gacaccaaaa
     2941 ttgagccaag aactggcaga taaaaaccaa gaagatcttt tccggaaaat ggaactgcca
     3001 ttgtctatca ttttggcaga gatggaaata agcgggatca aagtagatgc gactcgctta
     3061 caagaaatga agggcgagtt ctctgctcgc ttaagagaga tcgaacaaaa aatctacgaa
     3121 gaagccggcg aagaattcaa tttgaattca ccaaagcaat taggagtgat cttatttgaa
     3181 aaaatgggat tacccgttat caaaaaaaca aaaactggat attccacagc cgtagatgta
     3241 ctggaacagc ttcgtgaaca agcaccaatc gtagaggata tcctcaccta tcgtcaaatt
     3301 gcaaaaattc aatctaccta tgtcgaggga ctgctgaaag tgatccaatc agatggaaaa
     3361 gtgcataccc gttatgtcca gacattgacc caaacaggac gattaagctc tgttgatcct
     3421 aatttgcaga acatcccgat tcgattagat gaagggagaa agatacgtca ggcatttgtt
     3481 cctagagaaa aagactggct gatttattct tctgactatt cacaaatcga gttacgcgta
     3541 cttgcgcata tctcaaatga tgaacatttg aaagctgcct tcctagaagg tcaagatatc
     3601 catgccagca cagcgatgcg tgtatttgga atcgaaaagg cagaggatgt cacaccaaat
     3661 atgcgtaggc aggcaaaagc agtgaatttt ggtatcgtgt atggcatctc tgattacgga
     3721 ctttcacaaa atctaggaat cagccgaaaa gcagcacagc aatacatcga tacgtacttt
     3781 gaaaaatacc caggtgtcaa agaatatatg gaaagaatcg tacgcgaagc aaaagaccaa
     3841 ggctacgtcg aaacgctgta tcaccgccgt cgatatctgc cagacatcaa ttcaagaaat
     3901 tacaatatcc gttcttttgc ggaacgaaca gctatcaata caccaatcca aggaagtgct
     3961 gctgatattt tgaaaatcgc gatgatcgaa ttggataaac gattaaaaga aacaggtctt
     4021 caagctacga tgctgttaca agttcatgat gaacttgtct tcgaggtacc ggaaaaagaa
     4081 cttgaatcat tagataaatt ggtgaaggaa gttatggaac aagctgtttc tcttcatgta
     4141 ccactgatca ctgacagcag ttggggaaaa acgtggtacg aagcaaaata aacattgttt
     4201 aagacagagc aatataatga aggtgaaaag aaaaaatgcc agaattacca gaagtagaaa
     4261 ccgttcgtaa aggattggaa cggttagtag taggaaaaac gattcaaaaa gttcaggtct
     4321 tgtggcccaa gatcatcgag caaccagaga cacccatctt tgaggcttct cttgttggcg
     4381 aaaccatcca atccattgga cgtagaggga agtttttaat ttttcatctc gatcattgtg
     4441 aactgatctc acacttgcga atggaaggaa aatatcaatt tacgaaagaa aatacaccaa
     4501 tcgataaaca tacgcatgta cttttctttt ttgaggatgg aagccaactt cgctacaacg
     4561 atgtacgaaa atttggtcgt atgacaatcg tcgaaaaagg agcaagtgca acttaccgag
     4621 gaatcatgaa attgggacct gagcctttgc cagatagctt cttattagca gatttcgcaa
     4681 atggactgaa aaagtcccac aaagcaatca agccattgct gctagaccaa cgtctagtga
     4741 ctggtctagg taatatttat gtagatgaag cattatggga agcgaagatc catccagaac
     4801 aaccggcgaa cacactgcgc cccaaagagg tagaacaatt acgtctatcg atcattgatg
     4861 ttttggatcg tgcaatagaa gccggaggta ccacgattcg cagttatttg aatgcattag
     4921 gagaatcagg cggatttcaa gtagcactgc atgtctatca gcaaactggc aaaccatgta
     4981 tacgttgtgg aacgccgatc gtgaaaacaa aagtggcaca aagggggacg cactattgtc
     5041 cgaattgtca aaggctaaaa atcgcaaagt aggatttgtt ttaggtttga cgggtggaat
     5101 agctaccggt aaaagtacgg cagccaaagt ctttcagtct catggatttc ctttgatcga
     5161 tggcgatgtg attgccagag aaactgttga gcctggaacg cttgctctga ggaaaattgt
     5221 atcagtgttt ggccaagagg tattgcagcc tgatgggcaa ctagatcgag ggaaacttgg
     5281 gatgattgtt tttccatcaa aggaaaaacg gcaaaaactt gatcagctat tagatccgtt
     5341 tatccgaaaa gcgataaaag atcaaatcgc ctctctaagt tccaatcatc ctttagtaat
     5401 tgtagatatc ccattgctct acgaaggtca ttatgaccac tatatggatg cagtagctgt
     5461 cgtttatact acgccagaaa ctcagcttca gcgtttgatg aaacgtaatc aactgacgct
     5521 agaacaagcg cagcagagaa ttagtagtca acttccaatc gaagaaaaaa agcagcgtgc
     5581 ggatattttg ttcgacaaca atggaacaaa agaaaaactt gtgggacaaa tcgaaaattg
     5641 gctttttgct aatcgctttc tttgagtatc tgtgtcaatt ttgctatcct gagtatatag
     5701 aaagtgaggg atagcgatgg gatcattaaa aaatcaaaag gataaagtcg taggtaacgc
     5761 aaaagaaaaa atcggcgaga tgctcaataa agaaaatcta atcgatgaag gtcgtacgca
     5821 atcagaaaca gcagaagaaa aagaaaagca gtaccaagca agaatcgatg aaatagaaga
     5881 ccagcaggca gaagaagaag cgaagcggca agatttgact caagaacgaa aaaatccgac
     5941 acctgatcgt agtaaaacac cgctcccaga aagtgaccac atttccgatg agcaaaaaat
     6001 cgaggaacag cgaatgaaac actatacagg aatcgaagag aagttataaa atagtaaaaa
     6061 atcgagatgt gacttgaagc agatgagaag gtgttcatct gcttcaagtt ttttgtgcta
     6121 gatgactaaa tcagcttttg tgtaagttat ttctcagtaa tcaaggtgat cagtattgga
     6181 aaattgaaat ttagtaagga caggggacac aattacgcat gaaagtagaa aaaattgttc
     6241 ttatatccgt gttttttggg taggacagtc gcgtttgtga tttgtttcgt gttataatac
     6301 aactagttgt aaagaaagac acatccttta tataaaatgc gatgcaagag gtgagacaaa
     6361 atgagatgtc ccagatgtca acataataat tcacgagtaa tcgacagccg tcaagcagat
     6421 gatggacgtg cgatccgtcg ccgtcgcgaa tgtgagaatt gttcgttccg attcactaca
     6481 tttgaacgaa ttgaagctgc tccgttatta gtaatcaaga aaaacgggga acgcgaagag
     6541 ttcaatcgcg ataaaatttt aagaggactc atccgttcag cagaaaaaag acctgtagct
     6601 atggaacaaa tggaacaaat cgtcaaccat gtcgaaaacc gcgtacgcag tctcggagaa
     6661 aacgaagtat cgacgaatct aattggtgaa tatgtgatgg aagatttagt tgatttagac
     6721 gaaatcgctt atattcgttt tgcaagtgtt tatcgccagt tcaaagatat gtctgttttc
     6781 ttaaaagagt tgcaagatat cgtggataaa gcaaaagaaa ataataaaga gaataataaa
     6841 gaaaacaatt aagaaacaaa aaggaggcat ttccttggaa aatgcttgga aagagcttca
     6901 accaaaaaat atttaccaag gaagaaaagc ggctccgctg agagaagaca gcaagaacgc
     6961 cttgctgtat ctttatcagc cactaatcgg cggagaagcc ttgagtatct atttcaccct
     7021 gttatcagaa atctctcaag aatctggcaa aggtcctgaa gggatgcatg cagatctgct
     7081 tagtagtcta ggctgcggta tcccgcaatt ttatgatgca agaaaaaagc tagaaggaat
     7141 cggcttactg gatgtttatt ttaaagaaga tagtgatctg ggacctcgtt ttatttatga
     7201 gctgttagaa ccactcattc ctaaagcatt tttcaaagac tctgttctgg cttttcttct
     7261 tctggaaaaa gttggtgaac gacgattcca gaagcttacc caattctttg aacctaaaag
     7321 gcatacagca gagggatatc aaaaaatcac aaaaaaattt ttagatgttt atcgcttcaa
     7381 tgaagcagtg tacgctgcta atcaagaaaa catcgaatcg ctgaataaat cttttgaaga
     7441 atctgaatca gtagcattac ttgaagcaga ttcgacattc gattggcagt ttttgaatga
     7501 ttggctggca aaaaaacata ttgcaagtct tgatgatcca atcatcaaac aagtcgacat
     7561 gtatcatcag ctttacggtt tcgatgaatt gacacttggc gaactgatca gtcaatctta
     7621 tgactttagt gaacaaaaag tatctgaaaa agaactgcaa aaagccattt tggcaatgca
     7681 gagacgtccg gtgaagcaaa caaaagaaac agttgcggtt tctgaaaaca gtaatgaacc
     7741 ctcgtcaaac gaacatttga caaacgcagc gcttcagctg ataaaagaag cacagagcat
     7801 tccaccgatg aaatatctgg aagcaatcaa gtcagaaaaa ggcggatatg tttctaaaca
     7861 agaaaactgg ttactgcaag atcttgtttc tcaatcaggt ctttccagta gcgtgatcaa
     7921 tgttttgctg aattatgtac tagtgatcaa gaataatgct agcttaaatg ccagttatgt
     7981 aaatacagtg gcaaatgaat gggcacaaaa gaaaatcgcc acagcagaag aagcgatcca
     8041 gcacattcgg caaataagta atcaagcaaa acaatcaaaa caaaagaagc aaacaaatta
     8101 tcaaactggc aagcgaaatg ttcgacggga aaagcttcct gattgggtca accagccaaa
     8161 agatgaaaaa cagatcagca gcgagaaaaa agcagagatt gaccgccgtt ttaaagaata
     8221 cctggcaaaa aaggagggtg atatctagtg gaagacgtag gcaaagaatt gaagaggatc
     8281 atcagcaaac gcaattatca agaaaagtat gctgaaatga tcgctgaagt cttaaatgat
     8341 gcggatgttc aagcttttct aagcgcacac caagaagaat tgacacaagc ggatattgaa
     8401 aaaagttacg ctaaattgta tgaattcgtg caagaaaagc gtaaatatca aaaaaacgat
     8461 ccaacgatga tcgctcccgg ctatgagccg aagctgacgt tgaattttca ttatgtggat
     8521 gtcacttatg taccaacgga agcattgtta gcacggcaaa gacaagaaga aatcagaagc
     8581 cgagtaaaag caatggatat gccaaaagat attcaatcgg cttcttttga aaactttgaa
     8641 cgtacagatg gacgaggata tgcgagctta gaagccctag attttgtaga gaaatatact
     8701 gctgatccaa aagggtatca taaaggactg tatctagtag gaagttttgg tattggaaaa
     8761 acatatttat taggagcaac agcgagagaa ttagcgattg ctggattcac cacgacgcta
     8821 gtccattttc cgacatttgc cgttgagatg aaacaggcaa tcggaaaaga tcaagtggca
     8881 gaaaagttag atgcagtgaa acgttcacct attttgatga tcgatgacat tggtgcagat
     8941 gcgatgagta gttggatacg agacgaagta ttcggtgtta tccttcaata tcggatgcag
     9001 gaacagttac caaccttctt ctcatcgaat tttacaatgg atgaattgga acagcatttg
     9061 tccgtcactc aacgtggaga tgaagagccg ctaaaagcga aacggataat ggaacgcata
     9121 cgttatttga caaaagaaat cgaaatgact ggtcgcaacc gacgcaatgg ttgaacagtt
     9181 gacaagtcca actgacattt gacctagtag taaaagcagg tcagcgaatc attatatgga
     9241 cagaaatgac cggagacaat caccgcaaca agtaatgcag aaacttaaac ggaggatttt
     9301 ttatgagggc tattttttct agtatatctg tagttggtct attttttctt ttagcaggct
     9361 gcggtagcgc agatagcaac acaggttctg ttgattcgat tgatgcgggt caaacagtaa
     9421 aaacaagcag tacgaaaacg gagagacaaa gcatatttgt cggaacgatt gaaagtatta
     9481 ctcaagtaga agcagaagaa gaaacgcttc agttgaaact cgtcgatgtc atggccaaag
     9541 aagatccagc gaatatggga acgtcattca gcaatgacgg agtgatctta aatgctactg
     9601 ctgaaaaaat aagcgtggac ataaatgaat tgaaaatcgg tgacaaagtc caatttacat
     9661 tagttgagat gccgatcatg acgatgtcta tcccaccgca agttcctgga gattcgatta
     9721 ttgatgtttc attgaacaaa taaccaataa cattttttca aaaataagaa aatgttgttt
     9781 tatagaacga aaaggtatat tttttaagga gatatgggaa ttttttgg
//
LOCUS       DAFBSV010000096         9594 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.099, whole genome shotgun sequence.
ACCESSION   DAFBSV010000096 DAFBSV010000000
VERSION     DAFBSV010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9594
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.099"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            544..1107
                     /locus_tag="LLB18_002398"
     CDS             544..1107
                     /locus_tag="LLB18_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBK5245376.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
     gene            complement(1386..1673)
                     /locus_tag="LLB18_002399"
     CDS             complement(1386..1673)
                     /locus_tag="LLB18_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBK5245377.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(1663..1992)
                     /locus_tag="LLB18_002400"
     CDS             complement(1663..1992)
                     /locus_tag="LLB18_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBK5245378.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            2297..2626
                     /locus_tag="LLB18_002401"
     CDS             2297..2626
                     /locus_tag="LLB18_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5245379.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            complement(2913..3398)
                     /gene="vanZ"
                     /locus_tag="LLB18_002402"
     CDS             complement(2913..3398)
                     /gene="vanZ"
                     /locus_tag="LLB18_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HBK5245380.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(3551..4462)
                     /gene="vanY"
                     /locus_tag="LLB18_002403"
     CDS             complement(3551..4462)
                     /gene="vanY"
                     /locus_tag="LLB18_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HBK5245381.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            complement(4890..5498)
                     /locus_tag="LLB18_002404"
     CDS             complement(4890..5498)
                     /locus_tag="LLB18_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HBK5245382.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(5504..6535)
                     /gene="vanA"
                     /locus_tag="LLB18_002405"
     CDS             complement(5504..6535)
                     /gene="vanA"
                     /locus_tag="LLB18_002405"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HBK5245383.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            complement(6528..7496)
                     /locus_tag="LLB18_002406"
     CDS             complement(6528..7496)
                     /locus_tag="LLB18_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HBK5245384.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            complement(7711..8865)
                     /locus_tag="LLB18_002407"
     CDS             complement(7711..8865)
                     /locus_tag="LLB18_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBK5245385.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            complement(8843..9538)
                     /gene="vanR"
                     /locus_tag="LLB18_002408"
     CDS             complement(8843..9538)
                     /gene="vanR"
                     /locus_tag="LLB18_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBK5245386.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
BASE COUNT         2842 a         1951 c         1645 g         3156 t
ORIGIN      
        1 ttaaaacttt tttagcagat tttaaagttt cgtcaaaact aatatattct ggtagctgag
       61 cattcaaata gctttcagac ttcagaagaa aattacgagc atttttatag tccatctcta
      121 ataaagttat tcttttttta tccaatacat tcagctcaat tccttataat attctattcc
      181 ttagtatctc aacattattt actttataaa acgaataaat tttgtagttc taattcaaat
      241 attgcatgtt atatctaata tgggagcatt ttataatttt cattgtgata aactcgttat
      301 taactttagg atacactagt taggattaaa ttaggtatct agaaatttac ttaagatttt
      361 tttgtttatt tcgtatacac actcgtatca aaaacaatcg attatgagac aaaatgaaat
      421 gacctctttt attaaataaa agaggtcata ttttgtatca taacttgttg cattaactat
      481 gtatctataa ctccctttta tgatacaatc aagccagaat taaagtacga aaggaagaaa
      541 agcatgagtg gatacattta tggttatgcc cgagtgagta cacgttcaca agaactaaat
      601 cgtcaattag acttactcaa tgaacaaaat tgtaatgaaa tcctaactga gaaaatgacg
      661 ggaaccaaag cggttcgtcc ccaactaaat cgtttaaaag ataaaattcg tccgggagat
      721 acggtaattg tagaaagttt ttctcgattg ggtcgtagta caaaggattt gattgacctt
      781 gttacctatt ttgaagaaca ccatgttaag ctggtgagct tgaaagaaaa cttcgatacc
      841 agcacgcctc acggacgctt aatgatgact gtcttccaag catttagtca gttcgaacgt
      901 gatttaattg ttgaacgtac caaagaaggt ttgaaaagtg cacgtgcgag aggtcgtaaa
      961 ggtggccgtc cacgagtgaa ccagaaagat gttgatcgag cagtaaaatt gtataaaagt
     1021 caggtttata gcgtaaaaga aattacggaa atgactggta ttagcaaggc aacactctac
     1081 cgctacttaa aagacaatag ggaataatct attttaatct ttaggaatct ataatattta
     1141 tgggagaatt agagtgattt ttttattatt actaaaaaac aatataaaat aacgcatttt
     1201 aagccctctt tgtgcataag gatgaagctt ttaatttgaa agaggcttaa aatgcgtttt
     1261 aattttttct atttttcata aatatatagg ttagtggttt aaaattatag ggtattacaa
     1321 ctctcagctg ttaaaaatta tcttttaaag tgtcgtctat cctctcaagt tgaaacattg
     1381 ggttcttacc taatcttttt taattgttca taaaaatttt catgcgttcc acatagtaag
     1441 ataggtatca ctgcattatc tttaatttca tatgcaacgc gatatgtcgt acctgcatac
     1501 ttgaatccaa tagcccaaat tcctgataaa tcacccgttt tttgttctcc cgaatgagga
     1561 cgaactgcta tctcatcata aattatcgtt aaaaattgtt cttttaatgt tttctctttt
     1621 aattttttta gatactttat tacgtgttta gaaggtagaa tctcataagc caatttctgc
     1681 tgccaactcc tcttttgtca tcggtttaga atttgcaaca gtatcttcag caatagattt
     1741 aaatgcagaa gttaacgcat tttttctatt tctaaattct tttaagatct cttgtttgct
     1801 ataaccttct gaaagaatat cagccaaaat atcttcacta aaatcaaaaa attctttttt
     1861 aggctctaca aactcataaa ggataccatt ctctacaagc ttagcttcta cttcaacacc
     1921 attgggcaca tcgaattctt tagggaccgt taacataata gaatttcctt gttttcttgt
     1981 ttttgtaatc atattatttc ctccattatt ttacatttcg taattactta gtaattacat
     2041 tgtacgctat ttttagtaga aatacaaaat aataaaactc ctttagaaca attttcaaag
     2101 gagttttatt tgattaggaa attatgtaga ataataatat gtttttaact tggaatcaaa
     2161 aacgcacttg caagtaagtt tacttcaata catgaaattg cttataatag tgtattggaa
     2221 ttaaggtaga ttgacaaaag agtgatcaaa taggtatact tcattcaaat aatcgtttga
     2281 atgtgaggtg agatgaatga aaaaagtttg ccaagtgact gtcgtacata aagaaaaagt
     2341 aaatggaata aaaaataaat tggatcaaaa agatttttca aacttacttg tgttagggaa
     2401 atgtttcagc gatttttcta gaattaaaat tttctatgct ttagaaacct ataaggaaat
     2461 gtgcgtctgt gatttagcag aaatacttac tgctagtgtc gctacaacgt cacaccattt
     2521 acgtttttta aaaaaacatg gaatggcaaa atcacgtcaa gatggaaaag tagtttatta
     2581 ctctttagcg aatgaagaca tcctttccgc tattcgtgtt ttttaaagtt atcagaaaat
     2641 ctatctatga aatcttagtt tgggggtacc gtcaggaaaa tgcggattta caacgttaag
     2701 gaaatttatt aaagagacca attcctcagc actaaaattg ataattgggc tttctttgtt
     2761 actatagtgt taggtaagct ttttacttta tcaccggttt tcccctcact tcacacctac
     2821 gggcgagttt ccccacatcc cgttttccat ctaatccaat tcattcaata tctttatgtg
     2881 tatgaaagat cagattgctt gatttagaca tcttacacgt aatttattct taaatgggta
     2941 cggtaaacga gcaataatac gagcaaaagt atacctacaa aaataataac tctgtctaat
     3001 tttttttgat tcatatgctt attgcttaaa ccatataatt tcagtccaag aaagcctcca
     3061 acagtatttg taattacatc tgttatgtct gtcgctccaa tagcgaagat aaattgaatt
     3121 atttcaaaag taagacttaa aaccagtaca aaagcaaact taggtaaaaa tccgatttct
     3181 ttaaaattga cattcaaaag caagccaaat ggaataaaga ttataacatt atctatcatc
     3241 tctctgaaat tcccagtagc agtaaatgga gtcaagttaa gacttctttg atgataatta
     3301 aatactgata aaatattgta ttgtaatttg aataacacta accagattag tgtcactaaa
     3361 tataaagcta gcaatcctct agataatatt tttcccaata taatttcctc taattctttt
     3421 gtttaagttg tatcattagt atagcaatgt cctagttaac gtgggtttta aattaaaaag
     3481 ctaacgttac cccaaaagtg ctagtacaat aatgctgttc attaatttcg ttggtttcat
     3541 tccgccatcc ttacctcctt gaattagtat gtgttgatcc gggaaacact gtcacaatta
     3601 caccgtctat attgtttcct gatatctcat aacgaagatt agtcggcaca tgaatggtgg
     3661 tatttttagt aacaggataa taaaagatct catatttttc cccatttaca ctaacagaaa
     3721 tggttttttc ttcttttagg taatccatat attcctcgag aacgaaattc ttttctttca
     3781 taatcgcact atgtggtaaa ccaacatagc gaatatgcca tagttcatat tgaattcctg
     3841 ttaactctgt tttgtcctct ggataacgta aaatgaaccc gtatttccaa gcattttctt
     3901 ctatccactt tccttcaggg gctcgttcca ttttcgtcaa gcttgatcct acatctagtg
     3961 ataaacctga attatgctca ctataacctg ctggtaaggc atactcagcc cccatttctt
     4021 ggtaaagcac actttgctca tcaaagtctc gatagccact attaataata aaatgactaa
     4081 cgccaccctt tacagcatca ttgaccatct ctgaaaattt ttgtgctatt tcttttgaca
     4141 tataaatatt actatcaagc aacccgtatc catttattaa ttcgtcatgt ttagataaat
     4201 tcacgatatc tgacttcaca ctttcttggc gaacaggata tttactattg attaatagca
     4261 gatttccttg ataaacctgt tcttctgtaa ttgttttctc ttgggtattt tcagaagtcc
     4321 cactattttc taaatgttct ttgggatttt gatcataatt ttgaaattcg actttttcct
     4381 gagaaaacag tgcttcatta acgtagtcat aacctaagta tattaagaat aacaataaca
     4441 ataaaaaaaa caacttcttc attttcagtc tcctccttaa ctatatagtt ggaagtatga
     4501 aatatttcta gaatcttccc cttaaacggc acaatctcgt ttgagattgt gccgttttgc
     4561 cccgtaaatt acagtcaatt atttcgccct actggattta ctattatcac caatgtagat
     4621 gaattttcat aagtgatacc catgctgaat ttaacgaggc tgaactgcct gttgacaatg
     4681 ggcggtgtga aataccaccc ctctatgcga tcagtcttat tatcaggcta tcttgccgca
     4741 gcgcacgcag ataatgaccg caatatcgct ctgccttaca tcttcaatac tatctactat
     4801 atataaattc cctaagaacc agttacatac gtcgggtttc ctgccgaaag agttagctta
     4861 tatagtttgt ccgtgcaacg gttaaaagtt tatttaacgg ggaaatcaaa atagctattg
     4921 gggtatggtt cgtctcttaa tacatagtgc caccattcga ggctatatgc ttcaaaccca
     4981 ctgttttcca tgatggagcg caaacgtctg cgattttgcg cttcattgca tgatattcca
     5041 tttgccgcat gatgagagcg ttcatccata aaatcaaatc ggctccccat tggtacaagc
     5101 tcacccgtgt ctaatcgata aagcgtaaga tcaatggcac tgccgcggct atggcttgat
     5161 tttgaagcca cgtatccttt tgaaatcatc tcagttcggt caatattggg ataataactt
     5221 tcctttgtca ggttattttc cggctgtgca gcccattgca taaaacagtt tacagcacga
     5281 ttaggacggt aaccgtccca tagaagcaat ccgtaccctt gggtagcagc cagttctttt
     5341 gccttcaaaa gcgattcagc caactcgtat gtccctacaa tgcgatttac ttcataaccg
     5401 tcaaccggtt ttccggtgaa attatcccaa gtggcatatt tagcgtccca acgaacaccg
     5461 tgtactattt catctaaaaa agtaaatcct atttccatgc ttatcacccc tttaacgcta
     5521 atacgatcaa gcggtcaatc agttcgggaa gtgcaatacc tgcagcggcc atcatacggg
     5581 gataacgact gtatgacgtg aaaccgggca gagtattgac ttcgttcagt acaatgcggc
     5641 cgttatcttg taaaaacata tccacacggg ctagacctct acagccgagc gctttatata
     5701 ttttttttgc cgtttcctgt atccgtcctc gctcctctgc tgaaaggtct gcgggaacgg
     5761 ttataactgc gttttcagag cctttttccg gctcgacttc ctgatgaata cgaaagattc
     5821 cgtactgcag cctgatttgg tccacctcgc caacagctaa cgcggcactg tttcccaata
     5881 ccgcacaacc gacctcacag cccgaaacag cctgctcaat taagattttg ctgtcatatt
     5941 gtcttgccga ttcaattgcg tagtccaatt cgtccgcgct attgactttt ttcacaccga
     6001 aggatgagcc tgaacgcgcc ggcttaacaa aaacaggata ggtaaacgta gctgccaccg
     6061 gcctatcatc tttattaata acccaaaagg cgggagtagc tatcccagca tttttcgcaa
     6121 cgatgtatgt caacgatttg tccatacaaa ttgctgagct ttgaatatcg cagcctacaa
     6181 aagggatacc ggacaattca aacagacctt gtatggatcc atcttcacct gacttgccat
     6241 gcaaagctga aaatgctaca tcaacatggt tgatttcata ttcatggttc tttttaacaa
     6301 gtaatccgtg cattttttta tccggcgaga gtacagctga atagcaattg tcgttttccc
     6361 attccgcgca aggtttttcg cacattttcc atacaccaga tttcgtaatt ccaatgtata
     6421 acggctcgta tttttcttta ttaatgttag cggctatctc tattgcagat tttaccgata
     6481 cgtcatgctc ctctgagcaa cccccaaaca gtattgcaac ttttattcta ttcatgctcc
     6541 tgtctccttt caaaatccaa acagttttta atggtttttt caacggtatc acgcaacgct
     6601 tgctcggtat aataggccgt atgcggtgtg attatcacgt taggcattct ttgaagttta
     6661 agtaaaaatt gattatcaat tggtttttgg gtgcaatcag agtagaaaaa ctcttcctct
     6721 ccttccaata catccaatgc ggcaccgccc agtttcccgt tttctaatgc tttaaccaac
     6781 tcataggtat ctacaagtgg accgcgccca gtattgataa gaaatgctcc ttgcttcatt
     6841 ctctgtattt gttcgtggct gataatatag tgcgtatccg tattgagcgg cacatgaagc
     6901 gtaacgatat cgctattttg cagcaactca tcaaacggta catagtttac ctctatactt
     6961 cggctgcgac tataagccaa cactttacat ccaaatcctc gcagccgctc aataaccgct
     7021 ttgcctatct ggcccgttcc caccacacca actgtcatgt cgctgagtac cttgccacgg
     7081 tcgctgtcca acctgaaatc atgtttttcc acagagcgca caatcgattt tacgttgcgt
     7141 actgccataa gaattagcat catagtataa tcggcaacgc tatccggcga gtacgccaca
     7201 ttgtcgacag tgatgcccat tctcttagca gcagttgtat ctatatgatt gcagccgatg
     7261 cttcgggtag aaatatattt cacaccggct ctcttcagcg caagaagaat agaggcggaa
     7321 atctctgatt tatgtcccac actgatacat tgattgaaag gcgcggattt ggcgttggat
     7381 tccgacacgt tggcgttaat tatcgttgcc ataacgccaa agcgaggcga aagagcatgg
     7441 aatgcatctg cctcatcctg ctcacatcca taaacagtaa tgccgatgtt attcataatt
     7501 aagaccaacc ctttctgtga aaggcaccaa ataaaacggg gatgccaatg gtaatcttgt
     7561 caaatctttc tctgaagaac gaaaacggct cgttcttacg gtattaagtc taccgtgtaa
     7621 gaacgagccg tttcttaata ttaaattgtt aatttcctaa gaaaaagtaa agataacctt
     7681 gagattttcc taaaaaatta tatacatctc ttaggacctc cttttatcaa ccaagtctgg
     7741 catcgctgga agctctaccc taaacgtcgt atagttatca ttgctttccg cgtaaatctg
     7801 ccctccatgc tgaacaataa tttcttttgc aatcgccaat ccaagtcccg cgccacccgt
     7861 atcggaagaa cgagcattgt ccagcctata gaacttttca aatatggcag ctagcttatc
     7921 ttttgggatg cttccagtgt tcttgaattc gattgacacc acatccccgg agaggcccgc
     7981 ggtaatgtca atgatgctgt tatcctcact gtatgcagcg gcgtttttca aaatgttgtt
     8041 aaagactctc gcgagtttat cagggtcgcc ggacacggtc agatcctcgg gggcgtgaat
     8101 aaccgcctgt tttccatgtg cggaaagctg aggataaaat tcatcggtca tctgcaccag
     8161 catatagtat aggtctatgt gcgtttttgt tagcgttatc gtttgtaggt tataccgtgt
     8221 aatctcaaaa aactcgtcga ttagctgttc gagtcgatac gctttgtcca acgtgatatg
     8281 cacatacttt gccttttgat ctaccggcat gtctggagcc tcgtcaagca ggctcaaata
     8341 accgataatg gatgtaaggg gcgttttaat atcgtgcgcc aagtacataa caacgtcatt
     8401 ttttctttgt tcggccagct ttgcatcctg ctctcgcttt tccagagtcc gttttaatgt
     8461 gttgagcttt tgttccataa catccatttc cgcagaaagc tcaatttgtt tatcttcgtt
     8521 ctgaataagt acatcaatgc cggtatttat ctcgtcaaag tattttgcga attttgaaag
     8581 catgacgcga catagaataa gaatactaat gacaatcgcc acataaataa agatatctat
     8641 attgttccgt atggaatatt gatataattt catcgcgtcc aggtgattta agtcatattt
     8701 gttttccaaa atacttaaga tccaatcccc aagtttccct cggatcattg aacgaatata
     8761 caacacgaat acaattgcta ccacaacaat tgcaacgata tacatgtaaa gttttcgttc
     8821 tagtttggaa tagtcgtttt ttttattttt caattttata accaaccccc cataccgttt
     8881 ttatatattt cggattatca atggtgtcgt tcattttttc gcgcaaatgc cggatatgca
     8941 cggtgatggt gttgttgctc ttgctgaaat attcgtcgcc ccatatctca tgaaatagca
     9001 gctcggagct aaccacattc cccttgtttt cacagaggat tcgcagtatt gaaaactcgg
     9061 tgggagtaag ggataactgc ttctcgttca gataacactc atgggtgtta acattaatga
     9121 caaggccgga gtggacgata acattttcgt tctgctcctt tactccactg aattttttgt
     9181 atcggcgcaa ctgggccttt acccgagcaa ttaactccag tgggcgaaag ggcttcgtta
     9241 tataatcatc cgcgccgatt gttaaccctg taattttatc tacctctgta tctttcccgg
     9301 tcagcatgat aatcggatag gtgtgcttgt cccttatttt ttgacagata gtaaggccgc
     9361 ttgtgccggg aagcatgatg tccaatatgg caaggtcaat ctcagacttg tctatacatt
     9421 ccaatgcttc tttggcggta tagtatttga aaaccgtata attctcgttt tttaagtata
     9481 attcaaccaa atcggcaatt tcatgttcat catccacaat aagtatttta tcgctcatag
     9541 ttatcaccct ttcacataag tttgccctta ataatttatc agattatagg gccg
//
LOCUS       DAFBSV010000097         9318 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.100, whole genome shotgun sequence.
ACCESSION   DAFBSV010000097 DAFBSV010000000
VERSION     DAFBSV010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9318
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.100"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            317..1102
                     /locus_tag="LLB18_002409"
     CDS             317..1102
                     /locus_tag="LLB18_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBK5245387.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            1115..1966
                     /locus_tag="LLB18_002410"
     CDS             1115..1966
                     /locus_tag="LLB18_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HBK5245388.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(2090..2542)
                     /locus_tag="LLB18_002411"
     CDS             complement(2090..2542)
                     /locus_tag="LLB18_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5245389.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLMQTDISLVS"
     gene            complement(3007..3375)
                     /locus_tag="LLB18_002412"
     CDS             complement(3007..3375)
                     /locus_tag="LLB18_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HBK5245390.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            3525..4007
                     /locus_tag="LLB18_002413"
     CDS             3525..4007
                     /locus_tag="LLB18_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HBK5245391.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSEHMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLLNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            4044..5054
                     /locus_tag="LLB18_002414"
     CDS             4044..5054
                     /locus_tag="LLB18_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBK5245392.1"
                     /translation="MISYPLLERNTTIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGINLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(5169..5882)
                     /locus_tag="LLB18_002415"
     CDS             complement(5169..5882)
                     /locus_tag="LLB18_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245393.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSSDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPTHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
     gene            complement(6072..6662)
                     /locus_tag="LLB18_002416"
     CDS             complement(6072..6662)
                     /locus_tag="LLB18_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBK5245394.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQKEGWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            7185..7856
                     /locus_tag="LLB18_002417"
     CDS             7185..7856
                     /locus_tag="LLB18_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBK5245395.1"
                     /translation="MEPKDKYLDYARVNKDKFIETIIKGKIPDDEKDAVFMAGSPGAG
                     KTEVALGLAENYDNHVVIDADYFRAQFPEYNGKNSSVFQKASSWLVEQSLKYVLEHGY
                     SFILEDTFAILSAEKNIIRALKNNFRVTIFYVYQDPKVAWDFTRKRELAEGRHVPKEM
                     FINAFFKSRENIEKVKNRHPEVVLHIMIKDYQNDISEVHYAADNIQLVLPNTIYFKRV
                     GGGIT"
     gene            7853..8014
                     /locus_tag="LLB18_002418"
     CDS             7853..8014
                     /locus_tag="LLB18_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245396.1"
                     /translation="MTEKEQVQQIVKKYNKSIADLSENASAKEFKTVMKYVADEANRK
                     QRKLVGLDK"
     gene            8498..9268
                     /locus_tag="LLB18_002419"
     CDS             8498..9268
                     /locus_tag="LLB18_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HBK5245397.1"
                     /translation="MNPTLITKKELLKKLDISTGVLADLIRNGMPKEGEMFNLDKIIT
                     WRENWSKNILGELEVGRVYTNKEISEKFKCFKQGGMRRSHQTNTLVLFSDQTGSNVYK
                     DKWLNGILQYTGMGLKGDQVLDKNQNKVLANSKSNFVKIHLFETFKPKEHTYLGEVYL
                     AGQIYTVNEKDSSGNSRKVYKFPLALINQEQLIEDKDIYNQEENQTRHIRNLSDAKLE
                     EEARKVSNYNKKMAAKYVNEEEFCFSKTKIYKRTRGAS"
BASE COUNT         3206 a         1443 c         1762 g         2907 t
ORIGIN      
        1 ggctgtgaca aaagtcttgt cacagccttt ttttccaaat aaatggtttt tcagaagtag
       61 cttcttcgga aataagccga aatttcacaa aaatttgaga agtaattttt gtaaattact
      121 tcttatttct tgaagctggc cacttctgtc acaacctctt tctttataga aataaaagga
      181 cactagcaat tcatgaaaac gattgctaga gcgtatcatt tgctttagac tatatatctt
      241 ggtgtacact cactttaaga cggaaataaa agttatccgt aataacaggt ttaggtatga
      301 aaaaggagtg ggtactatgt ataaggaatt agaaaacaaa gtcgcagtag taactggtgg
      361 ctcaaagggg attggaacag cgattgctca acgattcggg aaagaaaaaa tgaatgtagt
      421 tgtcaactat aactcggata aagaaggagc agaaaaagca gtcaaagcaa tcgaagaggc
      481 aggcggaaaa gcagtctctg tacaagcaga tgtcagttct gaagaaggaa tacagcgttt
      541 acttgatacg gctttagaaa attttgggac actggacgtt tggattaata atgctgggat
      601 ggaaaatcag catccaaccc atgaacttag ccttgaagat tgggaaagag tattaaaagt
      661 caatttgact ggcgttttta tcggaacgaa agcggcttta aattacttta cagagaatga
      721 taaaaaagga aatatcatca atatgtcttc tgttcatgaa caaatcccat ggccaacgtt
      781 tgctcattac gctgcttcaa aaggcggagt aaaactattc accgaaacgg tagcaatgga
      841 gtacgcacca aagggaatca gaatcaatag tataggacct ggtgctatcc gtacacctat
      901 taatgcggca aaatttgatg atcctgaaca aaaagaactc ttggaaagta tgatcccact
      961 aggacgcgta ggtgaaccaa aagaaatagc ggcgacagct gcatggttgg cttcagacga
     1021 atccagttat gttacaggta ttacactatt tgcagatggt gggatgactt tatatccttc
     1081 tttccaaggt ggaaaaggat aagggtgaat aaaaatgggt ttattgattg cattgatccc
     1141 ggcagttggg tgggggatcc agccactgat tttgaaaaag attggtggca gaccaacaaa
     1201 tgagatatta ggaactggta ttggagccgt gctcgttggc ttacttgttc aattattcgc
     1261 ttctccagct ggtatttcag tgactacatt tttgattagt ttactttctg gtgcattctg
     1321 ggtcatcgga caaacaggac agtatacatc tttcaacttg attggtgttt ctaaaacgat
     1381 gccaatttcg actgcattac agttagtcgg aacctcattg attggtgtct tcgcttttgg
     1441 agaatggtct ggaagtatgg gaaaaatcat tggtgcagca gcaatcattc ttcttgtatt
     1501 tggttctgct ttaacggcaa tcagtgatga tcctggaaaa aaaggcggta tcacaaaagg
     1561 aatcagtcta ttagcatcaa caagtattgg ttattgggtt tacagtgcat tgcccaaact
     1621 agttgatgca agcggacttt ccattttctt tccgcaaatg atcggtgtct ttttaggggc
     1681 agtgatttat gtgattttcc gaaaaccaac cgcattttct gaagacaaga gttggaaagc
     1741 aacaatagtt ggagccatct tcagtgtgtc agcattggct tatatttttt cagcaaatga
     1801 aaatggggtt gctactgcat atatcattac acagctaaac gtagttatct ctacattagg
     1861 cggtatgtac atcctgcatg aaaataagac accaaaagaa aaaaaattaa cgattatcgg
     1921 attattgctg atcgtagtag gaagcatggt cacggtcttt atttgaggat aaagatggta
     1981 aaatctcatt tattaaaaaa atatttgttt gaaccaaaca gtaagtactt ataaaaaaat
     2041 agcgctagaa tttccaacat ctctggaatt tctagcgctt tttaattgtt taagatacaa
     2101 gtgaaatatc tgtctgcatc aataattttt cattgatcca ttgactaaag tttacgacat
     2161 aattgaagtt accaccgatt agtatctccg catgattgtc tttataaaga tcgtattgta
     2221 aaagacggtc ttttttattt gcgtaaacat cgttatggta ctggactaat tgttctcgga
     2281 attgattgat tgctgtaaaa tcacgatact gaaggttgaa acgcatcgtg attggtgcat
     2341 ttagcatgaa tcgctgcatt tcttttgctg cttcctctgc ttgatctccg tataggaact
     2401 caaaaagatt acgttcagaa aatttccatt gcccgccaac ctttgttcct tttagttttc
     2461 cttcatgaag ataatttctg atagaacgtg tagtaacacc taattgttcg gctaattcat
     2521 ttactgagta aaaatctttc aatgttcacc ctcctatgtg aatggttcta ctgacttagt
     2581 tgatatttgc ttaatcacga aatgtagaaa gaacgatttt aattaaggtc attgtaaaaa
     2641 tcaagtcaga aaattctaac ttttctttct ctaaagaaat tcgttctctc ctaaagtgat
     2701 attatattta aatatacctg aaaataatgg gcagtattat gaaagatcac tgatattttc
     2761 tcgtattttt tccttattca aaagttttgc aggaaaattg ctgaaaaaat aattttacta
     2821 agtggaaaat tcaaagccat tcaatcagtg atttttttca gcacaagaaa gactccttat
     2881 aaaaatagca gatactttgt caattaagtg tttaaccagg gatgataaaa aggataggat
     2941 tgaacaaaac ctgtataagc tgatgaatag tttcctcgcc agtaaaaggt ttattcgtat
     3001 aaagctttat cgccaaaatt tatcatgacc ttttttatct tcaatattaa atgaaatcaa
     3061 ttgttcaatc aattcccagt tgattacact tttccaagga actttgatga cgttatctgt
     3121 atatacgtag cctgcttctt ggatattttt ttcaagggca cgaatcgctg ctttttccgg
     3181 tgcgatagaa aaatgatttt tagcaaaact aaatgcaata ataaaggtac catggtcagt
     3241 aaacataggt tggttccatt ttacagttgt gtctagctgg ggatacgttt ctgttatctt
     3301 agcaaaaagg tctttgatct tttgttgatg ttctttttct ttgatctgat tgatgatcgg
     3361 ctgaaatttt tccattctaa aacgcctcca ttaagtggtt tgatttattt taccagaaaa
     3421 acaatagtta tgtataaaaa acgaacaaaa cacaagtaat gttgtaaccg ctatatttat
     3481 atgataagat gtctcaaata ataaaataga aaagagacat aaaaatgatt gacttggcaa
     3541 agaaattctt acacgaaaat atatattttg agttgtatca tcatcgagcc atttatacaa
     3601 atgaagatgc tttggtaata aagaaagaac aaggatttac aggtacagag accaaaagct
     3661 tattcttaaa agataaaaaa gataataact acgtatatct gacttttact acgaaacaaa
     3721 cggatttcaa agcattgggg aagatcgtcg gtaaaaggct ttctattgtt tcatcagaac
     3781 acatggaaga acaaacggga caaaagcagg gcgctgtttc tccgtttggt tatgaaaaac
     3841 agattccgat tattattgat gaagagctct tattaaatga aaaacttgtt tttgcaccag
     3901 gtagaccaga tcaaacgatg gtcatccaaa cggttgactt aaacaaaatc atccagctac
     3961 ttgagatgcc gatatttttg atgccggcaa acgaaaaaaa caattaacca agtaaaatag
     4021 tgcatacttg gaggtgaagc aacatgataa gttatccatt attagaaaga aatacaacga
     4081 ttggggttac tgcaccatcc tcaggcgtat cagaggaaca ccattcgtta ctcgaatcag
     4141 ctttaaagag aatggaagaa aaatctttcc aagtagttac tggaaagacg ctttggacgc
     4201 aagataagga aaaatcaggt ccagcaagaa aacgagcaga tgaattcaat caaatgatgc
     4261 aagatgaaaa tatccaaatg atctttccgc cttggggagg agaattattg attgagattc
     4321 tcgattttgt cgattttgat gctctacaac caaaatggat agtaggttat tcagatatta
     4381 gtacgttgct acttgctgtc acattaaaaa cagggatagc cactgcacat ggaatcaacc
     4441 ttattgattt aagaggagag tacttggatg aaacgacagc aatgtgggaa agtgtactga
     4501 aaacaagaga aggagaatcg attctacagc aaccttctga aaagtatcaa aaagagtggc
     4561 cccatgagca ttcatcatct tctgttttcc atctcactga accaacaaat tggcaatcag
     4621 tcagcggaga tgcagtaagg atgaagggac gattattagg tggctgtatt gatacgatca
     4681 gtcatttaat cggtacccct tatggagatg tccaatcttt taaaagaaag tataatgatg
     4741 gaaagccgat cttgtggttt ctagaaaatt gtgagctatc gtcagttgat ttaagaagat
     4801 cacttgttca gatgaaactg gcaggatggt ttgatggcag ctcggggatc atgttcggta
     4861 gaagtgcagc agaggatttg ttagattata aaatgaagga tgtatacgaa gatctgtcaa
     4921 aggaattaaa actaccgatc ttgtatgata ttgattgtgg tcatgtaccg ccacaactga
     4981 cattgatcaa tggtgcctat gcagaagtag cggtagaaga tagaaaagcg actgttttgc
     5041 aaacgtttat ttaaaaaatt ttttcctgcc ttggagttta tcaaagacca acaaatctaa
     5101 atagaaaaga aaatgaaaga agctgacagt attttgccag cttctttttg tatgatctat
     5161 tagaaatttt aattatccat aactatcaca ttgatcagct gtttcacatc atttggatta
     5221 cctgtaggaa tagctactac agatgcatta tcaataattt cttgagttgt ttctctaatg
     5281 aacgctggat aagatgtttg atctgcaggc atttgccaat gtgtaggaac tggataacta
     5341 gtgattgtcc cgtcatggtt acttgaatac actaaaactc cctggtaact gtatttccca
     5401 gtgagcataa ccacatcttt cggatagact gcactccctg catcataagg ggcgataggt
     5461 gttcctgcag gataatgaat aacatgtagt tcgaaatcac tcgatgtatc tctaaaagta
     5521 ttacctctaa tagctagcca aacacgtgcg tactcaattt gtagatcaga atatcctgct
     5581 aacggatcta ttgactgaga agactgtgag gaagttgtgt ctattgttga agaagaaata
     5641 tttgtctcaa ctgtactact agatgtagaa gaagtattgg gctctgagac tttactgctt
     5701 gttgaagatg tattcgtttc agtagaagct gatttctgag tacttgattt ttcagctgaa
     5761 ctggtttgtc tgattgaact tttgtctgtg gtcgcagatg gatcactatt ttctttacta
     5821 ggagacgtac atcctacaag gaataaagag accaacaata aaataaaacc taactttttc
     5881 atataaaata cctcattatt tttttaatac cagtatagcg taatcctgaa tttttgaatc
     5941 cgtaaaacct tgtctatgaa tataaataga gtatatcttc tttgataaat gtcagaaaaa
     6001 gtgtgacaaa taaccatcag taaaattact tgtcatacta ttgagaagga gtatttaatt
     6061 gaagagaatg attaggagaa aggatctccg tactttttat agtaatcata gaatccaagt
     6121 ttgtatagac gaatcgtttt ttctcttatt tcttctgttt caaaatggac tgcttgaaga
     6181 atcaagtctg tgaattctat aggagctgtt ccattcgcag taatcaaatt acgatctttc
     6241 acagcttgtt gttctataaa atcttcttta ttctgataat tttccgattc taaccaagga
     6301 aattgcgcat ttccggtgtg tttgtaacct tgcaataatc cgctctgagc taaataatca
     6361 actgccccac aaatagcagc tactggtacg tctgttttta acaatttatc gattatttga
     6421 tataaatgat gattttttat gtcccatgaa ttgccaccga tcataataaa aaggtcaact
     6481 ttttcaggta tttgttcgat taagtaatcg atttttgttt ttaatcctcc aatggaagtg
     6541 acctctgatt ggatagaagc agttttgttt tgccatccct ctttttggtt tagtgtgcta
     6601 gtaatataag caccttccca atcggcatat tcctctaata gaaacgtaat cgcagttttc
     6661 attttcaagc tctcctttac tatctatgac aaggacaaca gttttaacat acagacattc
     6721 attaaatttg gatagcgaca gcgaaaacaa caattcttaa gttttagaca gagtatacag
     6781 acagtcaact taattaaata cgaactaaat aaaaatgaca ggtaatcatt tttgtttacc
     6841 agcattataa cattttgcat acatggatga caaaagaacc aattcccact tgcttgagta
     6901 caatcttaaa agaaactgga aggcaaaaag taattataga aacgaaaaat aaatcatatc
     6961 gggcactcag acatgaaaac aaccctagaa atatataact agtccaatga aaaaacagcg
     7021 aatgccgtag aaaacaagga ttctgcgtac attcatatct cattttgcga gcatatctgc
     7081 tattactgtg actaaatgtt aatatggtta aaatgaccgt tatatttttt atataaatat
     7141 cgtataatta gtatgaatat agaagaagga aagaaggtgc aatcttggaa cctaaagaca
     7201 agtatttaga ttacgctagg gtcaataaag ataaatttat tgaaacaatc atcaagggaa
     7261 aaatccctga tgatgaaaaa gatgcggtat tcatggctgg aagcccagga gcaggtaaaa
     7321 cagaggttgc actaggttta gctgaaaatt atgacaacca tgttgtgatt gatgcggact
     7381 attttagagc acaatttcca gaatacaatg gaaagaactc aagtgttttt cagaaagctt
     7441 cttcttggtt agttgaacaa tcattaaaat atgtactgga acatggctat tctttcatac
     7501 tagaggatac ttttgctatc cttagtgcag agaaaaatat tattcgagcc cttaaaaata
     7561 actttcgcgt tacgattttc tatgtttacc aagatcccaa agttgcctgg gatttcactc
     7621 gaaaacgtga actagctgaa ggacgtcatg tgccaaaaga aatgtttatc aatgcgtttt
     7681 ttaagtccag agagaatatt gaaaaagtca aaaatagaca tcctgaagta gtccttcaca
     7741 taatgattaa ggattatcaa aacgacattt ctgaagtgca ttatgcagca gataatattc
     7801 aattagtact acccaataca atatacttca aaagagttgg aggaggaatt acatgactga
     7861 gaaagaacaa gtacaacaaa tcgtgaagaa gtataataaa agtatcgctg atttatcaga
     7921 aaacgcctca gcgaaagaat ttaaaacagt aatgaagtac gtagcagatg aagcaaatcg
     7981 taagcagcga aaactagttg ggttggataa ataaattttt taaaccatat ccttgtaaag
     8041 ttgagttttt tgttttaatg aattaagact attaaataga taattattgt aacttaaaaa
     8101 acacagctaa aaattagttg tgttttttat taggtttact tttctggtat aaaaggaact
     8161 agctactttt tcaaaatttc taaatcattc aatatgtagc gcttactaaa ttattcgcca
     8221 taaaatttta taattggatc actcattgtt ttacctaagt catatttaag taataaccgg
     8281 tgtttttaca taagaagact tggggtattt tttagtttga ttagctctga tatacctata
     8341 aagaatatgc taaggtaaga atagtaaaaa ttcacataga tgaggtataa taatgatgtt
     8401 tttatatatt acagataact tgacacaaaa tgagtttttt tcgatttttc aagttatcta
     8461 atgcaattat attgatatca ttaggagctg cattgttatg aatccaacat tgattactaa
     8521 gaaagaatta ctaaaaaaat tagatatttc tactggtgta ttagctgatt taattagaaa
     8581 tggcatgcca aaagagggag aaatgtttaa tcttgataag attattacat ggcgagaaaa
     8641 ttggtctaaa aacatattag gtgagttaga agttggtaga gtatatacta acaaagaaat
     8701 ttcagagaag tttaaatgtt tcaaacaggg tggaatgaga agatctcatc aaactaatac
     8761 tcttgtactg tttagtgatc aaacaggaag taatgtttat aaagataagt ggttaaatgg
     8821 tattttacaa tataccggta tggggctaaa aggggatcaa gtattggata agaatcaaaa
     8881 taaagtttta gccaattcaa aaagtaattt tgtaaagatt catttatttg aaacatttaa
     8941 accaaaagaa cacacgtatc tgggagaagt atatttagca ggacaaatat atactgttaa
     9001 tgaaaaagat agttcgggca acagcagaaa agtatataaa tttccattag ctttaataaa
     9061 tcaagagcaa ttgattgaag ataaagatat atataaccag gaagaaaatc aaactagaca
     9121 tattcgtaat ttatctgatg ctaaattaga ggaagaagca agaaaagtta gtaattataa
     9181 taaaaaaatg gctgcaaaat atgttaacga agaggagttt tgcttctcaa aaacaaaaat
     9241 atataaacgt acccgtggtg ctagttaatt ttaatatcct aaagaatatc tcaaagttcc
     9301 ttcaaaacgt cgttgtgc
//
LOCUS       DAFBSV010000098         9290 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.101, whole genome shotgun sequence.
ACCESSION   DAFBSV010000098 DAFBSV010000000
VERSION     DAFBSV010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.101"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            210..1016
                     /gene="proB"
                     /locus_tag="LLB18_002420"
     CDS             210..1016
                     /gene="proB"
                     /locus_tag="LLB18_002420"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HBK5245398.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1013..2260
                     /locus_tag="LLB18_002421"
     CDS             1013..2260
                     /locus_tag="LLB18_002421"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HBK5245399.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2336..2680
                     /locus_tag="LLB18_002422"
     CDS             2336..2680
                     /locus_tag="LLB18_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245400.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2797..3123)
                     /locus_tag="LLB18_002423"
     CDS             complement(2797..3123)
                     /locus_tag="LLB18_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245401.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3496..4698)
                     /locus_tag="LLB18_002424"
     CDS             complement(3496..4698)
                     /locus_tag="LLB18_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5245402.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            4815..5330
                     /locus_tag="LLB18_002425"
     CDS             4815..5330
                     /locus_tag="LLB18_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBK5245403.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5529..5975)
                     /locus_tag="LLB18_002426"
     CDS             complement(5529..5975)
                     /locus_tag="LLB18_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBK5245404.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6022..7500)
                     /gene="msr(C)"
                     /locus_tag="LLB18_002427"
     CDS             complement(6022..7500)
                     /gene="msr(C)"
                     /locus_tag="LLB18_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBK5245405.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(7854..8483)
                     /locus_tag="LLB18_002428"
     CDS             complement(7854..8483)
                     /locus_tag="LLB18_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBK5245406.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(8467..8931)
                     /locus_tag="LLB18_002429"
     CDS             complement(8467..8931)
                     /locus_tag="LLB18_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK5245407.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
BASE COUNT         2902 a         1920 c         1655 g         2813 t
ORIGIN      
        1 actactccta ttctaacata tccgaggctg taaaagactt tctttacaaa ttcttcaaga
       61 aattctgcta tcttaaagta aaccattaat tcgttctttt tccaaacgac tgcaagttgt
      121 acaaaaaaac tattttttac atgactttac tcgtcaaaac aagtagaata gaacgaaatt
      181 aatgagtgga tatttgattg aggtgtcaca tgcgtaaaga aattaaaaat gcaaaacgaa
      241 ttattgtcaa agtaggaaca agtacattga tttatcccaa tggaaatatc aatcttgcgg
      301 caatcgatca gttagctttt gtcctttctg atcttagaaa tcggggaaag gaagtgatct
      361 tagtctcatc aggagctgta ggcgttggta tgcataaatt acatttgtca gaacgtccga
      421 ctttgattcc tgaacagcaa gctgcggcgg ctgttggtca agccgaactg atgaatatct
      481 ataatcaaag attcagtgta tataatcaac agacggcaca gatcctcgtg acaagagacg
      541 tggtagatta tcctgaaagt cgtaaaaatg tgaggaatac attggaacag cttttgatta
      601 tggacacgat ccctatcgtg aacgaaaacg atactgtagc agtggatgaa ttagatcatc
      661 tgacaaaatt tggcgataat gatcagctgt cagccatcat ggcaaaactt gtcgcggcag
      721 accttttgat cgtcctttct gatatcgacg ggttttattc agataatccg actacaaatc
      781 ccgaggctca gatgtatcgc tatatcgata aaatcgatga aaagattctg gcacaagcag
      841 gtggtgctgg tagcacattt ggaacaggcg gtatgcagag taaattaaaa gccgcttcta
      901 ggatatttga agcaaacagc gcaatgattt tagcaaatgg aaaaaatccg gcaattattt
      961 ttgatattct tgcaggaaaa gaagtaggta ctttatttaa ggaggacttg aaatgactga
     1021 cttgatgcaa ttaggacaac aggcaaaaga tagcgcgcaa caactagcac ttatgcctac
     1081 aaaccgcaaa aatgagctac ttgttcaaat ggcacaaacc atcaaaaaga atcaacaagc
     1141 gatcattgaa gcaaatcata aagacttaga aaaagcagtc gaaaacaata tcagtgaaac
     1201 gatgcaagac cgcttgcagc tgacacctga gcgaatcaat gccatggcta cagagatcga
     1261 aaaaattgct tcgttagacg atcctattgg aaaagtagat gagatgtgga cgaacaccga
     1321 cggattgaga atcggcaaaa agcgcgtgcc actaggcgtg accggcatca tttacgaatc
     1381 tcgtccaaat gtcacgacag atgcagctag tctagcattc aaatcaggga atgccgttat
     1441 ccttcgcggt ggcaaagaag cattcttctc gaatcaatta ttagtccaat tattgcagca
     1501 agtactggtc agtgctggcg aatctcctta tgccatccag tttgtcgatg atacttctca
     1561 tgaaactgca ggacagttga tgcgattgac agaatactta gatgtgctga ttcctcgagg
     1621 cggagcaaaa ttaatccaac gagtcaaaga acaggcaacg gtacctatca ttgaaacagg
     1681 tacaggaaat aatcacgtat atatcgataa agaagcacag ttatctatgg cagtgaacat
     1741 catcgtcaat gcaaaagctt cccgtccatc tgtctgtaac gcggcagaaa cattgctgat
     1801 ccattctgag atcgcacctt ttttcttgcc agctattgaa aaagaactgg tagaacacgg
     1861 ggtctcttta cgtgcggatg ctcgtgcgtt agaatatcta gagacggctg ctttagcaga
     1921 agacacagat tgggatactg aatatctaga ttatatcctt gctgtcaaag tggtcgattc
     1981 tttggatgaa gcaattgcac atatcaatcg gcataatact aaacattcag aaacgatcgt
     2041 gacagatagt tatgcggcta gtcaacgttt cttaaatgaa gtggacgcgg cggctgtcta
     2101 tgtcaatgcc tccactcgtt ttacagacgg atcggtattt ggttttggtg cagagattgg
     2161 tatctctact caaaagttgc atgcccgtgg tccaatgggg ttaaatgaat taacttccac
     2221 aaaatatatc atttatggcg atggacaaat ccgcgaataa tgtttcgtgt gaaacattat
     2281 tcccgccttt tgcctttttt ctgtaaaggt tctatccaac tagaaaggtg tcaatatgtt
     2341 tgaaatttta atgatttttt ttatttacct tatttctctg aatatcgctg cttttctggg
     2401 agtcggtatt ttatcccttt tctttcaatt caaaaaacga agcataggga gtcaacggga
     2461 aaaatggtcg cagtattttg acaaaatcgg gcaaaaaggg ctggttacac gcttgcacat
     2521 tagttacatg gttgcattat gcttattagc gacaatcaat tactattctt ttttcgatca
     2581 ttcaatcgct tatacgatta cgctactgat tgctgggatt tttcacttat cttataaata
     2641 tcagctgaat aaaaaccact tgaatcggac tttccgctaa aaaatatccg tacgataagt
     2701 agagtgcctt gaagatcggc aaaaaactgc cggacttttt agaggctgtg acaaagattt
     2761 tgtcacagcc tctttttcca tataaacggc gttcgcctac cagctgcctg gtaaatctgt
     2821 ttcctcttcg ttaagaagcg aaaatccgtc aaatgtttcg ccatcataat aacgaagcag
     2881 ctcatccatg gacaagttca tcgttttttc tttttcttct tccgctgatt cagccagtag
     2941 ctgttcccga tacacctgat acataccagc tattttttgc tgcatcgctt ttctagtttc
     3001 accttccgca ttgattattg gcaattcttt gatatagcca cgataaatca accgatcatc
     3061 tgaaaattca atgggtaatt caacgagtgt caacccgact tcctgaaaat attcttccag
     3121 catctattat ccccccattc tttttcttaa atgaatttta gcttacctac tgaaaatttt
     3181 ccagtttcat tattttgaga aaaaaaggga atgtgacaaa aatcgtgtca catccccttt
     3241 ttccgaataa atggtgttct tctgccaact cctcaatcat aagtcacaat attcaacaaa
     3301 catgagaaac tgttttttga aattgttcct tgtgattcag agttaaacga cagtctcaca
     3361 acctcttggt aaacggcgtt caaaagcttg catctgcggt aataagccca accaaacgaa
     3421 aaatatgaga agctattttt gtttggctgt tcttatgact tgatgcagga cagctttttc
     3481 acaacctctg atttcttatt cttcttcatt tgtagcaaaa taattacggt gataaatgat
     3541 acaacataca ctgataagaa caatggcacc tgcaaaataa aacgcatagc tttcaccaat
     3601 atgttcacca atcacacctg caataaatgg tgctaaagct ccaccgaaaa agcggacaaa
     3661 actatagctg gacgaagcaa cgtttcgttg cagacctggt atttccatag caatcgtcgt
     3721 caacagtgta ttgataattc cttggaaaaa tcctgctaac acaatgctga tcggtacaag
     3781 gactggcata gaagttccag ctcctaataa cagcaaacaa ataatgaata agacaaatgc
     3841 tgctaaaatt gtccgataag tcgtaaactt ccgctcaaga gccggtgcaa cgaaaatcga
     3901 agcaatagcc agaagcacac cccagccaaa aaatacaaaa ccgacttcta attcagaata
     3961 gccaatcaat aaaaatggcg catacgcaag taaagtaaag aatccgaaat tatataacaa
     4021 tgcgattagt ccaactgaac gaagtttatg attgcttaac gctttgacac cttcccaaag
     4081 gcctactttt ctctttggtt tctcagtttc aggtaaaagt accgctaggg ctataaaacc
     4141 gcaaaacatc aaaaatgcta ccccaaaaaa tggataacgc catgaaccac tgcccaagac
     4201 cccaccgact agagggccaa cagccattcc gcagccaagt gctgcttcat acatcatgat
     4261 tgctttttct gtgttaccaa ctaaaatact gacgatcgtt gctaaagcag tagagacaaa
     4321 taaagcattc ccgacacccc agccggcacg taacccaatc agcattccga tattcccaga
     4381 taatccgcca agaccagcga atacaacgat gataaacaat cctgtcatca atgttttttt
     4441 caaaccgatc cgactagata agaaacctgt aaatagcatc accacaccag tgactaacat
     4501 gtaactagta aataacaggg tcgtttcagc tggcgtagcg tttaactgtg cagcaatcgt
     4561 ttttaagatt gggtctacta gacccactcc cataaaagcg atcatacagg tagctgctac
     4621 aactagcgct gaacttttcc cctttgtttc ttcatttgtt tgttcttgta tatctatttg
     4681 attctccaat atttccatcc ctttctctct attagcatca tacatgattt attttacatg
     4741 taaatatgca catgtaaaac gtggaaactt tactgtgata taataaagaa aataagacga
     4801 gaggtaggat ttttatgaat actttagcct atatattatt atgcgtgctt ttatccaaac
     4861 cacgttctgg gtatgaattg aagcagctga tcacaatttt ttgggaagcc catcacagtc
     4921 agatctatac aacgcttgcc aagttagacc agcagggtta tgtgaccgtt ttggacaaag
     4981 acgagcactc tcaaaaaaag atctaccact tgactgatga aggacgtgct cttgtagagg
     5041 aatggatcaa agaggaaact cccgctccta cgcaaaaaga tgaatttcta gcaaaaatct
     5101 atgctttttc gacgctcgat aaaacaacag ctactggact gctattcact agagaacaac
     5161 agctgaacaa aatcatgcaa aaaaatcaaa aaaaattgaa tgacctctcg ctagacaaga
     5221 aacaagaatt tggacgttat gttgtgatcc agcgcagaat tatgctttgt cagcaggaac
     5281 tccaatggtg tcagcaagta agagaacaaa tgcagcagtt ttttgagtaa gggataaaca
     5341 gaacctttct agaaatatct attgaagagc aaattatctt caataaaaga gcaatacagt
     5401 tggaaaagaa aaagcgatcc gaacgacagg ccaaaaccta tcgttcggat cactattttt
     5461 ctagaactgc attcaagaga ctatgacaaa aagcatgcca aggccttttt tcaaataaca
     5521 gtgttccatc attcattact ttgaattgct tttagcacac ttcttgaaag cgggccaacg
     5581 atgatcaact gcaacggtaa agcggcaatc acattcattt tccaagcatt catataagca
     5641 gagaataatt gatcaggtat tccttgttcc atgatcacac cgaataaaga catacatgtc
     5701 accattccta aaaccatcaa gcatgaaata gttaagatca tttggacctt gctttctgga
     5761 tttactggta gtttaaaggc aatttttttc gccagcacac cgatgatgaa gacatccaaa
     5821 atgaaagcca ccacgaatcc aggcactaga ccaatcaaca aacttgataa atgaagatct
     5881 tgatgcagcc ataaattata cgcgctcatc cccaagacca tcaaaaaaca catcattgtt
     5941 gtaaaaatta ttccttcttt tttatttgta ggcaatctgt accactcctt taaatttgtc
     6001 acgaaaatca tcgtagcaca tttaaaaatt tctcgtaagt acttttttta ttttctgccc
     6061 ttttatttca taaacttcat cagccgtacg ctcgacaaag taagaatcat gagaagtaaa
     6121 caaaatcgtt cccggatata tttgcattag cttctctaaa gcttcgatcg ttgccatatc
     6181 aataaaatta gtcggttcat ctaacagcaa cacattactt ggcttagtaa aaagcaaagc
     6241 aatcgtcaga cgggtcgctt ctcccccact taatgtacat aacggtttcg tcaaagtttc
     6301 ctgagcaaac cctaagtgat tcagcaaact acggacaagc gattctgaaa actctgtttg
     6361 tctcatgaca aaacgaatga tggattcttc agatgtcatt tgataaccct tttgctgata
     6421 tacttgaaag cttactttcg gagagagaag gattccttct ccttgtttgc ggatatgttc
     6481 taataaggtt gtcttacctg aaccattttc accgacaatc gcgatttttt tacctaaaga
     6541 aaactgaaaa tcaccattta ccagtaatgt tctcccactt ctttccaatt ggacattttg
     6601 tcccatgatg ggatagcggc tgtggagttc aagagatttt ggtactggaa aacggatttg
     6661 tttcatctgc tgcggcttgg ttgtttctcc tattttttgg agtcttctct ctaatgtttt
     6721 cgcattcttt tggatggctt tttgtacact gtctttttgt ttagaggaag acaaccgatc
     6781 cggtctgatt tgttgctttt tctttttact ggacactttt tccaactttt ccgcttgttt
     6841 tttcttttct tggatcgatt tttccaatcg ttttttctct ttcatgatcg actctgcttc
     6901 tcgtagctga gtctttttct ccaattcctt ttgagtgaga taggcactat aattccccga
     6961 aaactctcgg atttctccgt cttttacttc ccagattttc gatgctagct catctagaaa
     7021 atagcgatca tgactaacaa aaaccagcgt accataataa taacgaagct cttcaatcag
     7081 tcgatcaata ctttttctat ctagatgggt tgttggctcg tctagaagca tcccttgttc
     7141 ataagaagaa agaagacgta tcaactcgat ctttcgttct tcccctccgc tccatttccg
     7201 ctctgaagtt tcttccagtc ttaactggaa atgactggct aattccaaat ttaggtcctt
     7261 tgcttcagcg agataggtta attgaggcag gtagttgaag gtgatctctg tttggatttt
     7321 cccatgatcg ggaaaaagtt caccggctat tagtttgagc aaagtcgatt taccgacacc
     7381 attttctcct atgatcccta tacgatcttg ctgatagaca cgaagagaat caatagatag
     7441 ttctagctgg ttgccaaagc tgacttgtag atttgttata tttactgcta aattttccat
     7501 atgttttaca ctcctatttc atgtaaaaca acaattatcg atactaaaaa agagcagaaa
     7561 aatctgtttg caaaaaaact gcatcacatc ttttcctact ctgaacgaaa taactatgac
     7621 taaatcacca aatctgtcat agctttcacc tattctactg tcgttcgaaa aaatggacat
     7681 actccatcca tgaaattgtt gtttatacat gtcttttgaa tttatttagt tgttattcaa
     7741 aagttcgaaa cgtaatttca tcgatgcagt catttttccg acctcctttt ttattaggtt
     7801 accacacacg attcaaaaaa agcaatagct actgaatagt aactgaaaac cttttattcg
     7861 aacgtagtga tcttttctgg tgctaaacga acagactcgt aaccttcttc taccgctttt
     7921 cctattgata aaataataac tggaacataa cggtctttat ccaaaccaaa tgcctctgcc
     7981 aactgatctg cttcgaatcc accaattgga tttgtttcat agccatgatc acgcgcaact
     8041 aacatgaatt gcatagccgc taagctagaa tcgactttga ctacatcgtt catttcttct
     8101 cttgaaaaac tcttgtaata aggaatgatc gcagctaatt gttgatctct gacttctttt
     8161 ggcatcttcc ctgattcgta agcttggtta tagatttctt cgccatattc gtaacattgc
     8221 atatcgccaa aaatcatgac cattgcagaa gaagtatcat tttgtctcgt attgaaacgg
     8281 atcaaaggac gcaagatttc ttttgcttcc tcgctttcag cgaccacaaa gcgccatggt
     8341 tgcatattga cagaagaagg tgcagtcgtc gcttctttga tcatttccag catttcttcg
     8401 tgtgggattt tgtatgtttc atcatatacg cgaacggatc ttctaccagt cataattgtt
     8461 gaaaaatcat ttttttgttc cattattatt aacctctttc gtttctgttg ttatattgca
     8521 aagttgggta ttcaatttat ctaaaagtgt tagaaattgt ttcatttcta catcgctgaa
     8581 agccggggat agcacggaac ctgtatcttt atggtccatt tcacaatgct cgattttctt
     8641 ctgggctttt tctgttagcg ctacatacac ttcccggttg ttctgaggat ttctctgacg
     8701 cgaaacatag ccatttgctt ccaatacctt cagatgacga gtaactgctc cttgatcaat
     8761 ctgcaacttt tcttgcaaac tgctttgtag caatggattt tcttctttca gtctcatcat
     8821 gatctcgtat ctagtaagac ttataccgat attttcttca aagatctgga cgattttttg
     8881 atcggctaat ttgatttgat ataaaaggtg actaatctct tctaaagaca taatttcctc
     8941 ctttctaata attgactcgt caacgattga cttgtcaata atagaataaa aaaagaaaaa
     9001 agtcaaagaa tcagctgtgt aataaaaaaa acgctctcaa tagaaaagta tagagaaaag
     9061 aaattttttg tagaatgaac ggaaaaaatg ataaagaaag cacaacgcta aaaccaagat
     9121 tattgattct tatcaaacta tagaagatag ctcttctgca gtagaaaatt ttacaccgcc
     9181 aaaaatttcc gaaatcgcct tttgcaagaa tcccgtcgaa tattagaaat tggatcagta
     9241 tgcttaaaca gtaataaaaa agttatgaca agatgttgtc acaacctttt
//
LOCUS       DAFBSV010000099         9209 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.102, whole genome shotgun sequence.
ACCESSION   DAFBSV010000099 DAFBSV010000000
VERSION     DAFBSV010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9209
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.102"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            470..2107
                     /locus_tag="LLB18_002430"
     CDS             470..2107
                     /locus_tag="LLB18_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245408.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSMGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(2252..2992)
                     /gene="truA"
                     /locus_tag="LLB18_002431"
     CDS             complement(2252..2992)
                     /gene="truA"
                     /locus_tag="LLB18_002431"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBK5245409.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(3183..3818)
                     /locus_tag="LLB18_002432"
     CDS             complement(3183..3818)
                     /locus_tag="LLB18_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBK5245410.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(3965..5206)
                     /gene="sstT"
                     /locus_tag="LLB18_002433"
     CDS             complement(3965..5206)
                     /gene="sstT"
                     /locus_tag="LLB18_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HBK5245411.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            5404..6400
                     /locus_tag="LLB18_002434"
                     /pseudo
     CDS             5404..6400
                     /locus_tag="LLB18_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
     gene            6416..8434
                     /locus_tag="LLB18_002435"
     CDS             6416..8434
                     /locus_tag="LLB18_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HBK5245412.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(8494..9186)
                     /locus_tag="LLB18_002436"
     CDS             complement(8494..9186)
                     /locus_tag="LLB18_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBK5245413.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATVATTTTTSTESKSTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNADKSAQLEAF
                     MTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWSESGTGQA
                     DYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELK
                     NGFNQIVYGQAN"
BASE COUNT         2978 a         1706 c         1445 g         3080 t
ORIGIN      
        1 actaatcaga atcgtacaaa tatttaataa ccaaatatat agaacataac ttaatattaa
       61 gttatttgaa attccataaa aaacgactgc aggaattatt gtaagaaaag gataaaaata
      121 gttcagtcca tctccataat tgttaaatgt tgtatagttg attggccctt caaaaataga
      181 agataaccct ttgattcgtg aaagatgaaa agataaatca cctgttgtat aaatttcttg
      241 agcatttctc ataaaattta ctgaatataa agtactaagt aagataagaa ctactaaaag
      301 aaatgctttt ttacttattt tcatagattt gttgttctcc ttttttaatt ctattttcag
      361 tatactagaa ttgtcttttt ttaataagtt ttgcgttaaa tttttcatag cactagtatg
      421 atatactaga aaagaatcaa tttttattac ttttaaatag gagaaaaaaa tgaaaaaaaa
      481 caaaaaccaa ataatagata tcatttttat gttatttcta agttttgctt acgtcatccc
      541 tctattcatg tctatgggaa tctatcatag tgtcaatcag gatacttact ttcatttatc
      601 tcgaatcata ggactagata atgtatggag ttctccagta aacttcaata acttcgatca
      661 tcatggaaca atgatgaata ttttttatcc atggcttact ctttatccag cttttttatt
      721 ttataaaatg atgggaaatc ttgttttaag ttataatatc tactattttt ttatcacttt
      781 tttaacaatg gtcgtttctt atttttctat gaaacaaata aaaaacaatc gttatatttc
      841 gctgttattt tcgattattt atacattttc cgcctatcgt gccattgaca tattccatcg
      901 tgcttcattg ggagaagctg tcgctttaac atttttgcct ttgatactaa tggggtgtta
      961 cgaaatttat attagagatt accaaaaatg gtactggttg tctattggca tgacgctagt
     1021 agtgtatact catttacttt ctgtcgctat ggtttctgta tttattggag gaacgttgtt
     1081 tctttctttt tatttttggg accaaaaaat cgctagactc ttaagtcttt taaaagctac
     1141 cgtcctcacc ttttttttaa gtgcgggatt cttaattcct tttattcaac aatctagagc
     1201 acaagaattg aaagtcccac tgggaaaaga attaagtggt atggctccta gtgatatgct
     1261 gacacacatt ttaaataata actataacaa ctatactatt ggattattct tatttctcgg
     1321 attgattggt gcttttattt ttataaaaaa attaactgct gatgatttat ttattttctt
     1381 tcttggtgta tttgttcttt tttgttcaac caatttattt ccttggcaac tttttaacca
     1441 tacaccagtt aagagtctac aatttgtctg gcggttaaat ggtttttctt ctttatttat
     1501 agcctatacg atgagtatag tgatctatta tattttttct actaaaaata attcatggaa
     1561 aataatggtc tttacgtttc ttgcactaat attgcatctc tcaggagtaa gcaattctat
     1621 ccatgctaac aaagattcat taacacttat agcacctgaa gacgctgttg ctatagctga
     1681 aaattacaat catactgatt atgcaaacaa agagtcaatc tatcatcctg atatgattaa
     1741 taatgatcaa tatttactag gtaaccagga aataaatcca acaactcatt ttatgagtaa
     1801 caaacttaca attgaattag ataattcgaa taataaaaat actgtcttga cgacacctat
     1861 ttatcgttat aaagggcaag tggcttctat taatggcaaa ctagtacaaa caaaattatc
     1921 taagtttggc acaactgaat taactattcc tccaggtata aataaagtcg ttattactta
     1981 tcagtacaca aaactagcaa ttgcttcaag atatttatct atcgttactt tgattttatt
     2041 tttactttat cgatttactt tttctaaaca aaaacaaccg agaagagaag tacaacattc
     2101 tcactagatt tttatttaag aaagactttt tagctgtaca cataaacagg ctaaaaagtc
     2161 tttttttata tttctttaat ttgcttcata cattatttaa catcgatatt tatactgtga
     2221 aacatgcgtt tcatccatta tcaaagtatt tttatcgata ataaacttca tccaaaaaca
     2281 gaccttgtgc agggacggtt tctcctgcat gttgccgcac tttgctttca aatatttcat
     2341 cgattgtttc tatcggcatg gcacctgtgc cgatttctag taatgtcccc atgataatcc
     2401 gcaccatttt atataagaat ccgtctccga caaaagtaaa atgaagcatt tctccctttc
     2461 gttcgataga taattcatca atcgtacgca ctgtggattt ttttgatttt ttcaatgcag
     2521 aaaaaccaat gaaatcatgt gtacccacta atttttcgca agctgcattc agcttgtcca
     2581 tatccaactc ttgagggaaa taaaagctgt ggtttcgctc aaatgctgaa ggaatcacgt
     2641 tgttccaaac ataatagctg tattttttgc ccaccgcatt atatcttgaa tggaagcgct
     2701 caggcatttc ttcgattctt ttgatgacaa tatcccgcgg aaggtaacga ttcataaagt
     2761 cgatcatttc tgccagtcca atttctgtgt ttgttttaaa atttgctact tgtcctcgcg
     2821 catgggtgcc agcatctgtt cttcctgatc caataatttc tatctcttca tttgtcatct
     2881 gatgcaatac tttttcgatt tttccttgaa tggttttatc gtcatctcca agtctttgcc
     2941 atcctgaata tctttttccg tcatattcga ttgtcaactt gatgtttctc atattttagt
     3001 ggctcctctg tcttccattt ggtcttctct ctaccttttt aagattgtag cacaaaatat
     3061 agctcctttc ttctctaaaa cagaagctat acaagaaaac tgtggaaata tatatttcag
     3121 aaaaacaaaa aacagccacc ggatgaagta tccgctgact gttcaatttg acggctcaag
     3181 ttttactgtt tgagatgcaa gatactcaac caggcaatgg gcacataatt aaagaaaaaa
     3241 ctgattcttt ggcaaaaacc tattttattc agtaatggcc aagaatttat agaaggaatt
     3301 cttgccagtc cataaatcgc cgcaaaaagc aaactgatca cagacagtcc aaggtataag
     3361 tggcttacgt ccatttgccc attttttcga tagatcaaga aaagaagaac tggaaacaat
     3421 aaaaaaccac tgtaacctaa acctgatccg atattatgga cccatgtcga gacattccac
     3481 gaagattcat gggtattgat actgaacaaa cctgtaaaga tacaatcacc tataccatag
     3541 aacgcgatgg ctgctgtaac tagggtagct aacacacgag atgtacttac aaatgcagca
     3601 tacaatgcag gcaatgacag gatgaaaaag atccctgaaa ccacagacca aataagaaac
     3661 gcttttctta caggactgga aacctctcca aatacactga tcacgctctt catttgatct
     3721 aattcaggat aatacaatcc taatacgtac ggagtcaaaa aatcactcag cacgcctaat
     3781 aataaaaaga aaaaaccaaa tttacgtaaa aaatccatga tacgcctcca ataacaatta
     3841 cctatgcttt taattgttat tataaacgac tttatcttga tttaacagaa acctctattt
     3901 acacgaacat ctatataact cattaaaaac tcgaatcatt ttaaaaatac taaatatcta
     3961 acgttcaacg ttcacttaat ccatctaaac aatctttcaa tttgattttt tccccacttc
     4021 ttttacgcgc gcctagctct cctattgcag taaacaacag atcacttgac gaatttaagg
     4081 cagtttccat tgaatcctgg ataacaccga taataaatcc aataccgacg atttgcatcg
     4141 cgacatcatt agagatacca aacaaactac atgctaatgg aatcaataac agtgaaccgc
     4201 ccgcaacacc tgaagctcca caagcagcta aagcagacaa aatacataaa aggactttca
     4261 aaacaaaagg tgcttcaatc cctaaagaat gtacagcagt caacgtcatc aaggaaatgg
     4321 taatcgcggc accgcccata ttgatcgtag cacctaacgg gatcgatatg gaataagact
     4381 cttttgtcaa tttcaatctt tcagccaaca tcatgtttat cgggatattt gcggcagaac
     4441 ttcgggtaaa gaaagcggga agtgcgcttt ctttcaaaca aaagaaaatc aatggatagg
     4501 gattttcttt aataaacaaa aacgtgagga atgggtacac aactaatgcg acaaacagca
     4561 tcgtaccgat caaaacaagt aaaagctgca gatactctgc caatccagcg attccagtcg
     4621 tagcaattga ttgataaacc aatcctaaaa tccctatcgg agcaaatgca ataatcactt
     4681 gtacgacttg tgacaacgct atagatatct gatccaccaa ctcttttgtc gattctgaac
     4741 gtgctcgaaa agctagtccc aacaatacag cccagaataa gacgccaagg taattcgcat
     4801 caataagaga ttgaacagga ttttgtgtga cattcgtcaa catagtagat aaaacacttt
     4861 ccaaactttg cggtgctttt tcagatactg tttcttgtaa agtaatagga acagtaaaaa
     4921 ttgaacttac aataactgct acaagtgcag aaagcaatgt tcccactaaa tataagatca
     4981 aaataggctt cacgaatgtc ttattcccaa ttttatgctt ggcaattgac gccatcgtca
     5041 agaaaaaaac cagaataggt gcgattgcct tcaagcaact gacaaacaac gttcccaata
     5101 ttgaaataaa tgtccatgtg gggaaaaaga taccaaacaa tattccgact aaaataccaa
     5161 caacaatacg ttgaactaac gacatatcca aaaacttctc taacaaatga ccaccctttc
     5221 acaattttaa caatcattgt atcattttat gcaaagaaac taaaggtata attttctaaa
     5281 aattctaaca atacaaacaa ccatttcttg ctaattttgt actttttctg tctacacgtt
     5341 gttttttgag atattctaag ttaggatgtt attaatgggc aacttatcag gaaacgtttt
     5401 cttatgtttt tgtccaattt ttttgtgagg tgtttattct tgaaaaaaat aaagaaggag
     5461 agttatggct tcctgacaat ctttgtcgct tgtataatga tggttttaca gcgtatattg
     5521 atttcagcag tcactattcc tacatatgca acaaaccctg gtcgattcta catctataca
     5581 tttttacaaa cttccgttgt tattggtgca aatttgatcc cactttacat gggttaccaa
     5641 tatcaaaaaa tcgcccgttt aaaagtttta cattatttaa gtcgttttgc ctttatattc
     5701 ctaatagcca cactagtttg caatatcttt tttttacgta caagctggca gcttgaatat
     5761 tcgtgattat tggcttatcc taacacctat cagtcagaat tactttactt atgctgtttc
     5821 ttgtactttg cttttttgta gtattcctta tacagttgga tttttaaata aattatcgaa
     5881 aacaacaatt aaatatctac tattattttt aacaattgga ttagttggct gctctactct
     5941 atttaataaa gacccgtttg cattacagaa tggacagagt attttatgga ttttttattt
     6001 atttttaatg ggttatggtt tgaaagaatg gaactggaaa gaaaaggtcc gctataagct
     6061 tcctcaagta tttatcagct tgattgtttt attcggtttg attattttga tgacacaaat
     6121 ttcactcatc atcagaggaa atacagatac agcgctgagg ttttctaaac catattctct
     6181 cttcgcaatg tattatactt tctcttcgtt tttattttta gaaatgctat ctgataaatt
     6241 aggtataaaa ggaagaggaa attttcttgc tgtatttttg attgtcactc aagttatatg
     6301 taatttccct ttagtttctt atcgcgtatc tacatttatg aaacgtgaat ttccaaactc
     6361 agggaaggca tggctgataa atatcgggca gttttttatt tgctatttat tagcagtgtc
     6421 cctcctagtt atctttttat tttatataca aaaaatccgt ttcattcatc gtttcatcga
     6481 atacttcgct tttgattcga ttgaacaatt aactcagcgt tggaaaaaaa gaattcattg
     6541 gctttttgtt cataaaagtt attttttagt tgcagcattt ttttactgct ttaccttcgt
     6601 gcagattttc gttttagaac caaaagaagg ttggaaagaa actatccagg ttgccttaaa
     6661 aatatttact cagcgacaag cacccatgat cctgacaatc atcattatta tgggattttt
     6721 cttcttacta ttgttgattt ccaatcgttt ttggtacgcc ttgactgcta ccttgatcat
     6781 taacttactg ctcactattt cgacagtaat caaaatggaa atgcgggaag agcctgtctt
     6841 tccttcagat ttaaaaatgc tgaccggatt gtcagaacta ttatcgatgg ttagcccagt
     6901 cttattaatc gtgggcggat tgatccttct cctattattg attactagta ttattgtaca
     6961 acgtagacta caaaaacagt attccttgaa gattcattgg aaacgtcgat ttatcagtat
     7021 cgctgtatta ttaggatgtt tttcgggtgt ctttttcatt aatcacaaaa attcgccttc
     7081 tttcttgctg tttaatttat ttaaagtaaa caagactttc tttaaccagc aaggcgccgt
     7141 aaaagataac ggaccagtca ttcaattcct aaacaatatc gacattaaaa tcatggaaga
     7201 acctgctggc tattcgaaag aaaaaattaa tggaataatg aaaaagtaca acacaaaggc
     7261 agatgaaatc aaccaaacaa gaagtgactg gttaaacaat cagacgatcg ttctcaattt
     7321 aagtgaaagc ttcagtgatc ctgcacgtgt ccctaatctg acagtaccta cagaccctat
     7381 tccttacatc aaaagcatta taacagaagg aacaggagga ttgatgttat ccgtcggtta
     7441 tggtggcgga acagctaaca tggaatggga aggactgaca ggcttgagta tcagtaacct
     7501 gtctgcttcg ttagttacac cttataccca gctagtggag cgtcagaaaa taagtccaaa
     7561 tattaccgat ctattcgatg aaaaaatagc catccatcct tttacagctg ctctttatcg
     7621 cagaaaacaa gtgtttgata aatttggttt tgacaggttc tattatttag acagtccgga
     7681 taaattaact tatacggata aaatagaaca aagcccacgc atatcggatg attcagcata
     7741 caaagaaacc ttgaaagctt tacaaagcaa tacagaaacg tcacaattca tccaattatc
     7801 cactatgcaa aaccatatgc cttatgatga ttactatagt gaattgaact acactgctga
     7861 aggaactgct gtcattccta atagaagaaa agaattacaa acttatatgc aaggccttca
     7921 ctataccgat acagcagtaa aaaaattcat ccaagaaatc gacaaaatcg ataaaccgat
     7981 tacctttgtt ttttatggtg accatttacc cgcaatctat agtgggaatg attcgaaaaa
     8041 atatggatta gaacagcacc agacagatta tttcatttat aacaacaagt atagtcgtga
     8101 acaagcagct acgttaaata aagaagttgt tgctcctaat aactttggtg ctatggctct
     8161 tgagcatgcg aatatcaaag taactcctta ctatgcgttg ttgacagaag tatctaatca
     8221 tctacctgca ttaacaattg atcctacaga aagcttgtct aatcgtttta atggaaaaca
     8281 ggtctttgtt acagaggata gtcaaattat ccaagaaaaa aatttaactg agaaacaaaa
     8341 agaaattcta gaagattatc gtctgataca atatgatctt gttgcaggta accagtacag
     8401 tgcaacatgg gcgacacaaa aaataaaaga ctaacaaata aactgagcaa ggggttgtga
     8461 taaaagacat gtcacaaccc cttgtttatc tcattaattt gcttgtccat aaacgatttg
     8521 attaaagcca tttttcaatt cattattcgc tgtctcgttg aagtaaagat aattatcggg
     8581 attcccctga ttttgttgtg tcaccaatac ttttggctga ttttgctgaa acccgaatag
     8641 atagacgtgc tttttcagat atggttctgt ctctgcatcg gaatagacgg ctgtgatttg
     8701 atagtctgct tgacctgtcc cactttctga ccattctgca gaaacaggca ctccaccaat
     8761 agccatcttc cactccccgt tcaaaatagc ttgagggact ttaagaccat ataagtccac
     8821 actcatttga ttcgtataac ttttgtattg ttgtcccatt gtttggcccc atttggtcat
     8881 aaatgcctct aattgtgcgg atttgtctgc attccacagt gtttgttcaa cttgttcgct
     8941 gctttctgaa gaggaagatg aagcctctac agaagaactt gaagtagatg tttgagttgt
     9001 ttcagtcgtt ttggaagact ctgacgaagt agaggtatct gctgtttctg tacttgctgc
     9061 agttgacttg ctctctgtgc tagttgttgt agtagttgca actgttgctt tcgctgtttc
     9121 ttttgttgat tcttttttcg attcattccc gttggtacaa ccagctaaca aaaaagctag
     9181 accaattgtt actaaaatcc tttttttca
//
LOCUS       DAFBSV010000100         9190 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.103, whole genome shotgun sequence.
ACCESSION   DAFBSV010000100 DAFBSV010000000
VERSION     DAFBSV010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9190
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.103"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(559..1599)
                     /locus_tag="LLB18_002437"
     CDS             complement(559..1599)
                     /locus_tag="LLB18_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBK5245414.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(1948..2274)
                     /locus_tag="LLB18_002438"
     CDS             complement(1948..2274)
                     /locus_tag="LLB18_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245415.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2261..3064)
                     /locus_tag="LLB18_002439"
     CDS             complement(2261..3064)
                     /locus_tag="LLB18_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBK5245416.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3417..3707)
                     /locus_tag="LLB18_002440"
     CDS             complement(3417..3707)
                     /locus_tag="LLB18_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBK5245417.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(3843..4022)
                     /locus_tag="LLB18_002441"
     CDS             complement(3843..4022)
                     /locus_tag="LLB18_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245418.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(4019..4369)
                     /locus_tag="LLB18_002442"
     CDS             complement(4019..4369)
                     /locus_tag="LLB18_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245419.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4362..5687)
                     /locus_tag="LLB18_002443"
     CDS             complement(4362..5687)
                     /locus_tag="LLB18_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBK5245420.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            6137..6751
                     /locus_tag="LLB18_002444"
     CDS             6137..6751
                     /locus_tag="LLB18_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBK5245421.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(6916..7920)
                     /locus_tag="LLB18_002445"
     CDS             complement(6916..7920)
                     /locus_tag="LLB18_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245422.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINV
                     FFYSKEKLADFSNIAEMIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLE
                     LKTLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITA
                     CEIGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEK
                     RNKLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNK
                     SQITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD
                     "
     gene            complement(8379..8636)
                     /locus_tag="LLB18_002446"
     CDS             complement(8379..8636)
                     /locus_tag="LLB18_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBK5245423.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(8629..8898)
                     /locus_tag="LLB18_002447"
     CDS             complement(8629..8898)
                     /locus_tag="LLB18_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBK5245424.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(9029..>9190)
                     /locus_tag="LLB18_002448"
     CDS             complement(9029..>9190)
                     /locus_tag="LLB18_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245425.1"
                     /translation="NKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLLIAQEKA
                     GFEVPALKK"
BASE COUNT         2841 a         1645 c         1295 g         3409 t
ORIGIN      
        1 cgttgcgggt aataccgtaa cactgaaggg cacgcattaa ggcgtcatct taatgctttc
       61 ctgtaggaca ctgacggaga ttaccagtct cccgagcctt acaggggcct ttcttttttt
      121 tgtattttca attatcacaa tttatcgtcc aaaagtgcag aacgaaaatc aattcatcac
      181 aagcatatca gacaattaaa tttaaaacaa ctaaaaatat acaaaaaagt gtaattgaat
      241 attagcagca ctgcctgaaa agaagtaata tcaggctttt cagcttgggg aaataagtga
      301 attacctctc ttcatgaatt attataactc aaaaaagcac atatgcaaac actagttccc
      361 tatttttttg aatgaaaaat aactaaaata tctaacgatt atgactttaa aacctacgtt
      421 tgtgattgtt ttcataaact tttaatctaa aaactccgga ataatagcta tttatttgta
      481 acatttgtaa taaaattaaa atcataaaaa agttctaatt taaaattgat catttttata
      541 gtgatcgctt tttatcaact actctagcca attttccgta ctaactgttg gtaattcgtt
      601 aaatgtttct ctttgttcgt ttgcaagctt tgccgcaata gctttttcga caaaccaatt
      661 ttttacataa acgaaaatta gattctgcaa attgtttact ttttcagttt tttgtttttg
      721 ataagctttc agcaaagtca tatataatcc tttgtcagca tcaattccat aagattccag
      781 ttcttcataa acaacaactg tttgctctaa ttcttcagct tttttctttg cattatgaat
      841 agtttggacg gttttttgag cgtcttcgta agtactagaa aatgttttta tcaagtttaa
      901 tacattttct ggtacaaatg tatttatact gtcctctttc atgatgtcga cgaagttatc
      961 tagtaaaact tgattttgta actgatcagt ttcagtgtct attatgtgtc tattagtgtc
     1021 tatagaatta gaatagaata gattgtctgc gattttcgca attacggttg agtccttgat
     1081 atgactggat tttgccgtat ttgcgatttt cgcaattacg gtggtatcat tgatttctcg
     1141 cggttttgcc gtatttgcga ttttcgcaat tacggtggta tcagtattgt cttcctcttc
     1201 catgatttta aagacgtctt gattcgttac ttctggcttg cctaagtaca ataaattagg
     1261 catggattca atcttaccgt cacgtttatt tactcttcct ctcttctgtt tcagaagacc
     1321 tgctttttct aattcctttt tgattttaga tactttacct tcgcggcatt gtaacaattt
     1381 cattaattct tcaactgtga atatgaaaaa tatattatca tcagaatcta cccagttatt
     1441 tttgactgaa taatcaaatc gatctttaag tagcatataa gcaatttttg catcatttga
     1501 tagatccatg tatttttcgt tagtaaaaaa taccttaggc atttgataat atttttcacg
     1561 ataaatttct tttgatttgt aataattaaa atcattcata gccaatcctc tttctgtagg
     1621 atagcgtttt gttcaaaact atgttacaat gaattaaaca aatatatcta tccactatat
     1681 atttttctac tgctgataag tcgccaaact ttgttaaagc agtagtcttt ttttatcttt
     1741 ttttagttta ccttaaaaaa taaattaaag caaaccgctc tatttcaagg tttaagctca
     1801 tagtaactat atcacgatat tacaataata ttatatcacg atatcgtaat attacaatat
     1861 gaagataagc gacttatcag ctttgatact actgattttt ataaaaaaaa tatcacgata
     1921 ttatgatatc gtgatattga atgtaaatta aattttattt tgtttctttg ctagtttata
     1981 tccttcaatc aagtattctt caggtatgga ctttaatagc gcatcttcta taacgtctgg
     2041 tttacttttg tctgattcag caatagtcgt ccaatatttg agtgctgaca ttagaattgg
     2101 atttatacga atgctatctg ctgttcttac actacttcct tgatctttta tgactttact
     2161 tatatttttc ttggttaatt cgatttcttc tacttctttt gatttaaaat tctttttatt
     2221 tttatttcct agtaatctac ttactgcagc ttgactgcga ttatcttctg ccatcaaaat
     2281 caccaacttc ttttaaatat tcttctgtaa atgctttata gtcatcttca gctgttgagg
     2341 gtttattaaa attgattaga tctgatccag cagcttgcgc ttcgtcaacg gttattgtcc
     2401 tacgaatata agttttgaaa atttttgcac caatgactct agaaatttcg gttgctgcag
     2461 acgtcatttc tttagaaatg ttataacgct tattatactt agtaaataga actcctcgta
     2521 cttcaagctt gtcgttcgta tattctttta ccgtttcaat agtttcactt aactttatta
     2581 gtccttttaa tgagaaatac gcagcttcaa ctggaatgat aatttcatca gaaacagtaa
     2641 atgcgttgac tgtaagcatt cctaaacttg gtggacaatc aattataata taatcatagt
     2701 tgtccttgat tggttgaagt actcttttaa gcctgtgttc acttcctact tgagtaaatt
     2761 ccctctctgc agaagaaagg gctatgtcgg ctggcaaaac atcaattcct ttatagtcca
     2821 gaatagcatc tgtaatgtca gcctcccctt ttaatacttc ataaattgta ggttggtttg
     2881 ttccatctat atcgaaacct acattatctg tagcatttcc ctgaggatca atgtccacta
     2941 aaagtacatt tttaccgtaa acaaatttca aacatgctgc taaattaacg ctagtcgtag
     3001 ttttagaaac tccacctttt tgattggcta ctgacaatat tcttgccatt aaaatatccc
     3061 ccattcatct tatattataa tataattata tcataatatt gtgatattgc aatatcgtat
     3121 atgcattata ttgtaatatt gtgtgattat tttgttttaa agatatatat cggttcggat
     3181 ataaagatta ttcatatgtt attcgaaatt aaaataatca ctttttatta ctttaaaatt
     3241 ttttattaat gataagaaat atgttttgcg agcagcaact agaataattt aaacattact
     3301 aaactgtcta tattgttact aataattccc ttcttatagt gcattttctt agaaaaaaac
     3361 aatattacga tatcatgata ttaagatatc gtaatattat acaattgtga ttgatattat
     3421 atatgttttt ttattttttt atcatgttta atcttgaagg aatcatattc tttttctaaa
     3481 gacaggagct tttcataaac atcagacatg tttaaactag aggccaggct taaatcataa
     3541 acgaatgaag caggtaatga ttttattcta cgttgtcggg ttatccagct tgcaaccgtt
     3601 ccttgtgggt aggcatataa ctcacaaaat tgttctacag tgattcctaa attcttgata
     3661 atgtaaacat tgatcgggtg cgagtaaaca aatgtattga tagacatggt gcgtaagcct
     3721 actttctttt attattgcgt ttgcaataat agtttaacac acgcattatt ctagtatcta
     3781 ctcctatttg taaaaacaaa aaaggattca tagagataac tctatagaat ccgtaaaata
     3841 ccttatatat ataacgggaa gatataaaac ctaaaattat gataacctgc tgcagcttct
     3901 acatagaaag agaagcgctc aacaccaacc tcatttatca aacgttggcc ataaccccaa
     3961 atctcttctg atagctgatc aaaggttata tactttagct catattgctg gataatgttc
     4021 attctaatcg actccattta ttatcctggt aaaattcgat atgacgtatt tcgtcgtagt
     4081 gaattttgtc ttttccaacg tagatcccca gctcatcact acctaagatc ttgccaatga
     4141 tatcttctgg atagtatcct tcagcgtttc gttcttcttt ttgaatagat actgatctat
     4201 tttttatgac tgcagcgttc aatacttccg caatctcttc agtcgtcatt tgttcttttg
     4261 ctaaattttg actggttcgt tgttcattgt cggcatcaat ttcttcagta tgatcagata
     4321 aataaaaccc tgcccacttt aaacgtccac gatcattgta atcaatcatt tttaattccc
     4381 ccatttccgc ccgcatgacc accaacaagt gtgcttctag taatgcttct agcgccttct
     4441 aacattgaag aagcatgtac aatcgacgta aaaccatatt tttgccgaat cttgtcaata
     4501 attttatcta aattttcttc gtcaatttgc ttttgtggat cactaaataa atccagctga
     4561 agcgaatcgg tgtacacaag cttgctatag gttattccaa catgccttac ttcttgtcct
     4621 tcataatact tatcaaacaa gaaaagacaa taattctgca attcctttgt attatctgtg
     4681 atagggatct tcatctggtg tgaaaaccct ggtctcgttt ctaagatcga cgtgccaatg
     4741 tgtaaatgga cacaacctgt tttacagtta tgctgcctaa tgcgtatcgc tacttgttcc
     4801 gccatttctt ttaccaccag ctcgatttca tttcttctag tataatctcg tggtaacact
     4861 tgtgaatttc catatgattt ttcctttgtc ggttctggtg ggattgctat atctgttcga
     4921 tcgatcccat tagcatggaa gtacagctgt aagccaatca cacctagtct attcttaatc
     4981 gtataaggat tccagttagc aagatctcta atgctcataa tccccatctg attgagtctt
     5041 tttttcattc gagagccaat tccccaaaag tccgtcattt caggaatatt ccatactttt
     5101 tcaggaacgt tttcgtacgt ccattccgca acaaatcctt cattatgctt tgcttcgttg
     5161 tctaaggcta gtttagccaa aaggggatta tctccgacac ctactgtagc aatcaatcct
     5221 agctcttctt taatattctc ctggatcatt tgagccagct tctttctccg ttgacttcgt
     5281 gttccttcag tcgtaaaaag attcagtgat cgggtcactt ttaagattga ttcatcgatc
     5341 gagtaaatca gtagatcttc atcagccaca tatcttctga aaatattatt tacctgcata
     5401 tttcgcttga tatataggtt catacgtggt ggaacaacgt gtagtgtttt aggaaatggt
     5461 tgtggtaagt cacgtggtct actcacattt gtaataccat accgcttttt tgcttcagga
     5521 gaagaagcta atatcaatcc tgaaccagta ttatcagctc gactcataac aacaagttct
     5581 gttgttaatg gatctaaatt tctttctata cattcgacac ttgcgtaaaa gcttttcata
     5641 tcgattaaaa agtaatcatt tactggctct tttgaataat ccatcataaa taacactcca
     5701 ttctttcaca ttatacaaac atatgttcga tattgtaaag aagaaatagc taaatacata
     5761 aaaaaagaag cataggtatg ctatcaccct gcttcttctt ttgatttgta tgatcaattt
     5821 attctatcac tttactaatt aatttgaaaa tctaataaaa actctcactc taaaagagtg
     5881 agagactgca aattagagta cggacttttt tggagttccg ttctttaata ttaacaaatg
     5941 aataaaatcc ttacaacatt tgagaataag ttatcagtag acacttacaa aaaattctca
     6001 tactatttcc tccatcatta gtttttgtct atataaggtt taccctaaat agacactggt
     6061 ataacattga aaaatatggc ttcctcgtgt atgattaggg tgtattttaa atagttgcag
     6121 aaagtaggta aaagttttga gagttgcata catacgtgtc tcatcgatcg atcaaaatga
     6181 acaacgccag attgaagaaa tgaaaaaatt cggtgcagag agaattttca tcgagaaaca
     6241 atctggcgca acgattactc atcgacctgt tttccaagaa gcattagatt acgtccgaga
     6301 tcaagatatt tttattgtgg aagctattga tcgacttgga agaaattatg acgagatcat
     6361 cgcttcagtc aattacttga agaagaaaaa tgtgaagctg atcattacta gtttaccgat
     6421 catggctgaa gcaattggca atcctctcct ggataaattc attaaggatc tgatcatcca
     6481 aattttggcc atgatcgctg aacaagaacg gactgaatcg aaacgtcgcc aggcacaagg
     6541 aattaagatc gcaaaagcaa acggcgtcta caaagggcgg cccaaattat acagtgcaga
     6601 cgcaaaagat ccccaacgtc gccttgttta caaaagcatc gttgaagatc ttaaaaatgg
     6661 tgttgcgatt gctaagattg ctaaagacta caatgttacg agacaaaccg tgtatagaat
     6721 aaaaaaagac agcatggtca atgacaaata gttgatcatg ctgcttttat tatcttctca
     6781 tctttaattt cctacatata attactatct ataaaattaa gtcttactca gaacagataa
     6841 agcataaaat tccaacaaac cattttttac ttaactaaat aaagagtctg ttaatataat
     6901 cttcacttat ttacgttaat cccctactgt atttgttggt tccttatcta tattttctac
     6961 aaaatcctta ttatcttgtg atttagcttc gtataattct ttgtatgtcg acacattggt
     7021 tatactaatt cctatagcta gttcttgaga ctctactttt ctctctagct cctttgacaa
     7081 agtgatttga gatttatttg gttccgttgg agtcaattct atagattctt cataaaaatc
     7141 tctatacata aagctatcat taattttata aaaaaaatta aatgttttta gcactgccat
     7201 ataacattca aaacattctt ctatagttgg tttacttcct tgaggagaat gaaccaattt
     7261 attacgtttt tctatgaaat ttttaatttc ctttcttatt tctttcggaa actcaatatt
     7321 aaagtaccct ttaaacatgc tccctaataa tttgtctaca gggggagatt gtaaattctc
     7381 aaatattaga gttaaatcag gtttctcttg ttgataaaat tcctttaccc ctatttcaca
     7441 ggctgtaatt atcgaaataa acctatctct agtatttgat atatttttac ttcttttaag
     7501 gagtataaga gaaaagggga tactttcgtg tccatgcatg taattaacta attgttgagc
     7561 ttcagaagtt atatctctaa ttatatagtt aacggaatta ggaagtgtct ttaactctaa
     7621 tgaaatttct atccaattac tatcttctaa tctgtatatg ctcgaagtat aatttgattc
     7681 gtcagcaagc atcgctacat cccaaacact gatcataaaa tcttttaaac gttcaatcat
     7741 ttcagcaata ttgctaaaat cagctaattt ttctttagaa taaaaaaaaa catttatatc
     7801 agaatcaata aattctattt tttttattac tatatcgtca tcattatctt gaccatttat
     7861 gtttattgtt ccctgagtgg ggagtacttc tttcaaattc aagttaaatt tatattccat
     7921 tacttctcct ccaatatata aaaattactt aactgtatcc aaatttaata tgtaaataaa
     7981 tcattaattt ttagctaaat tctatgagaa gtttattttt gttgtttttg ctaattaact
     8041 aaaactagta caaaaaattt aaaatagatt attaaaccta ttgcttattc tattcagtca
     8101 tatatataag cgtcatcctt tagtaactaa catcccacac tacaatagta ttataacata
     8161 tctattcaac ttcaaattgt tgaaatttaa gccatttata tttacttttc ctcaacttta
     8221 gaaatgattt tactaacctt atatccgtaa tacgcgtaac aaacacattc attaataaca
     8281 atcaacacta agctatatta gctttttaaa tgactagggt aaataaaata aggatcaaaa
     8341 acttttaagt ttctgaccct ttccttactt ccgattggtt aatagtgatc ttttgcagaa
     8401 taaataaata tcgtttcatt ttcaactcta tatatcagtc tatgttcatc tgtaattctt
     8461 ctggaccatt ttccagataa atcatgcttt aatggctcag gttttcctaa tccagcaaag
     8521 ggggaacgat cgatatcttt tattaacttg ttaatctttt ttatattgct tttgtttcct
     8581 tgctcatgcc aataaagata atcatcccaa gcatcatcag accaagcctt aatcatcaga
     8641 ttcaacctcg attaagtcat gtgttttaaa tgcacctttg gagaattgtt catctcctcg
     8701 acgaattttt tccatgacgt aattattaga aagtgttctc aacgtttctt gcatagaatc
     8761 ataatctctt tttgataata caacaactgt atcttctaca tctttacttg ttacaataag
     8821 tgtttcagca tcctcattaa cttgtttcat ataactacgt aaattttggc ggaaatttga
     8881 ataagctact gcttccattc ctttcacccc ttatttattt ctataaaaca attgtacatt
     8941 atattgtaca attaagcaaa tgattaatat tctaacttct tataattaaa agtgctatca
     9001 cttttagttt ttaggataaa aagtgacgtc actttttgag tgctggtacc tcaaatcctg
     9061 ctttttcttg ggcaatcaat aaatctaacg caatacacat aatcctggat tcacttttgc
     9121 cgtacttctg ctttagttgc tgcaattctt tttgtctctt ttcatccaac gtaacgggta
     9181 accgtttatt
//
LOCUS       DAFBSV010000101         8969 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.104, whole genome shotgun sequence.
ACCESSION   DAFBSV010000101 DAFBSV010000000
VERSION     DAFBSV010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.104"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(57..350)
                     /locus_tag="LLB18_002449"
     CDS             complement(57..350)
                     /locus_tag="LLB18_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HBK5245426.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(378..1043)
                     /locus_tag="LLB18_002450"
     CDS             complement(378..1043)
                     /locus_tag="LLB18_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBK5245427.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(1183..1815)
                     /locus_tag="LLB18_002451"
     CDS             complement(1183..1815)
                     /locus_tag="LLB18_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5245428.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(1822..2889)
                     /locus_tag="LLB18_002452"
     CDS             complement(1822..2889)
                     /locus_tag="LLB18_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBK5245429.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(2886..3617)
                     /locus_tag="LLB18_002453"
     CDS             complement(2886..3617)
                     /locus_tag="LLB18_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HBK5245430.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(3786..4265)
                     /gene="greA"
                     /locus_tag="LLB18_002454"
     CDS             complement(3786..4265)
                     /gene="greA"
                     /locus_tag="LLB18_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBK5245431.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(4401..5576)
                     /gene="mltG"
                     /locus_tag="LLB18_002455"
     CDS             complement(4401..5576)
                     /gene="mltG"
                     /locus_tag="LLB18_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBK5245432.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            5780..6949
                     /locus_tag="LLB18_002456"
     CDS             5780..6949
                     /locus_tag="LLB18_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBK5245433.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(7216..8850)
                     /locus_tag="LLB18_002457"
     CDS             complement(7216..8850)
                     /locus_tag="LLB18_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245434.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDS
                     ELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLN
                     IIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNM
                     VKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPN
                     KDEITFTLKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTI
                     RYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
BASE COUNT         2857 a         1701 c         1332 g         3079 t
ORIGIN      
        1 aatattttca aaagaaaaaa gagaaggtga caaaaattgt gtcaccctct ctttttttat
       61 tgttttttaa agtgataggt tggctcctcc aggttgggat cataatcaac aagtaaatca
      121 tatcctttaa agaaccattc atctgcttcc tcgataaaaa aaagtgtccc atcaatttcc
      181 actttcttta caggatgttc tggctgttca actgacattc caatcgaaaa accatcatga
      241 acctctgttt tgccgtagac ttttccaaaa aaacgtattc cgtaagtttc tggcagatca
      301 atttctgagt caaaccactt ttgtgctttt ggcgttaccg ttaatttcat cccaacaacc
      361 tactttctct tttctttcta ttgattcatc ttatcgtcta gaatatccac atcgcctgtc
      421 tctccaataa ccagtagatt atcattttca cgaacatatt catctgctgc aggagaagcg
      481 ataaccgttt gatctactct tcgtatggcg actactgtta agtcaaaacg ttgcctgaaa
      541 tttaattcag ctaatgtttt gttgaaaaat ttaggattgg agactcggat ttctgctaaa
      601 gaatatttat ctgacaactc taggtaatct aaaatattct ttgacactaa attatgcgca
      661 atccttattc ccatgtctcg ctcgggatgg acgacgcgat cagctccgat cttttcaagt
      721 actctggcat gatactcatt ttgggctttt gctaaaatat ttggtacgcc catttccttt
      781 accatcagag taactaagat actggcttga atatcttctc caatagcgac aattacatga
      841 tcgaaatttc ttatgcctaa tgatcgaagt gtcatttcat cctgtgcatt tgccacaaca
      901 gcatgagtgg ctatattcat atattcattg acccgatctt cattactatc aatagccagt
      961 acttcttgac cagcttcgat cagtgttcgg cagatacttc cgccaaatcg tccaagacct
     1021 acaattgcaa aattttgttt caccgttttc ctcctttagt atcttctttt ctcagtataa
     1081 caaagccttt acaaaaacaa aagcaagcat cattattgta aaaaagccaa gaaaaataat
     1141 agttattttc tcagcttttg attatcctct ttatcatcgt ttttatttca ccaaaccatg
     1201 tttgaatgca tagatagcgg cttgtgtacg gtcttccact tctagcttag ccaatatatt
     1261 ggaaacatgt gtttttactg ttttcagtgt aataaacaat tcgtccgcta tttcctgatt
     1321 actttttcct tcagaaatca gcattaaaat ttcattttcc cgattcgtta gttcttcatg
     1381 taatacaggc tcatttcgcc gactcatttt ttccatcatt tttgttgtca cttctggttc
     1441 taatactcgc tcgccacgtt gcgttgccct tatagcatca gcaatttcat gtgcggtaga
     1501 ggtcttcaac aaataccctg ctgcacctgc ttcaatggca ggataaactt tttcgtcatc
     1561 aataaaactg gttacgataa tgattttagc ttctggccaa tcttttaaga ttgcttttgt
     1621 tgattcgata ccatccattt cttccatgac taagtccatt aaaatgacgt ccggtcgaag
     1681 tgtcatcgcc ttctcatagc cttgtcgtcc attttcagct tctccaatta cttcaatgtc
     1741 ttcttgaata gataaataag aagagacgcc taagcgcacc atttcatggt catctactaa
     1801 taaaactttt atcatcctta tctatgcctc cttcatcaaa gggaccttga tttctacact
     1861 tgtaccttga cctttaaaac taatgatttt tactgttcca ccaataccag ctactcgttc
     1921 tttgatattg ttcaatccat aacttcccgt tttcgtttca ttcatattaa accctgttcc
     1981 gtcgtcaata atacgtaaca aaagattatt gtctattttg tgcaaatata cctctaattc
     2041 attggcttta gcatgtctta atgtatttga taacaattct tgaacgattc ggaacaagtg
     2101 atcctcaatg gaactagata gttttacatc ttctacatcc catttcagcg aaatctggat
     2161 tttattttgc aattccttca ataactgctc gataccttgc tttaaacttt tctcttctaa
     2221 attgactgga cgtagatgaa gaagcagcgc acgcatctca gactgggaag cgttgatgat
     2281 ctctgctacc attttcaact gcttgcgaaa catttctggt gtctcgcttt tttctgcttg
     2341 ctccgtcaat gccgacatca tcatcattgc tgcaaacaat tgttgcgaaa ctgaatcatg
     2401 cagctcacgg gctaatcgat gtctttctaa ttctaaaatt tcttctttgg tttgtccatc
     2461 tacatattgg ggacggctcg ttacaatttg taattcacta gatacttcaa tcattttttc
     2521 ttttatctta gtgatttcct tatcaatatc tttgatgtat aaatcgtccg atgcacttgg
     2581 gatcggaaga agcaacaatt tggattcata attgccagaa gaaagtgcac gcagcttttc
     2641 ttcgattttc ccgtattttg tcttttgaat aagtgataat aatagaaaga caattaatcc
     2701 tacacctaag gaaatggcta acaaatggaa gataagcgga acatataata aacgtgcacg
     2761 cagtaattct ccccaccaat gactttgatt gctggcataa aaataagtga aaagtgaaaa
     2821 tagaataata aggaaagccg caatccccga ataaacagct agcatcgctc tggatatttt
     2881 tcccatcata ttcgtatcac ctcgacatct ccaatcaagg tattagtaat aatcttcaat
     2941 ctacgagggt tttcatcata atcactgctg tagattttga tttgttcatt tttcaaagaa
     3001 aattgctctt cttcaaacaa gacatttcct actaatgtcg catgctctaa tcggatggct
     3061 acgcccaaag gtactaagat ccgtgttctg cctatccctt ttcttacaat cacaatatta
     3121 tcatcttttg gcaaaagcgt attgcccaaa tctatgatag tatcaccaga aatgacggcg
     3181 atgttgatat cgtcccattc atagacgtcg tttccaatac gttggttacc gaataattgc
     3241 tgtcttttcc gctcattatt atgtgttttt aattgctctg tttggatcat catgatctgt
     3301 ttctttcgcc aaaaagcatt tttggttaaa tctatccctg aaatctctac acctttcaga
     3361 ccaataaata aaacggcaaa tacagccatc atccataaag caggactgtt gactaagcta
     3421 aaaaaaatga ccaaacttcc taatatcaat tgaaaatttt gaaatttagt acgaggatgt
     3481 ttgcgcatag ctaaatatat attgaaaata ccgaatatca ctaaaagcaa aagtccagta
     3541 ttgtttacga tttgccaaac agcaaataac agcagtagtg cttcaactac cacaaaaaaa
     3601 cgccaagaac tattcatcgc tctttctccc tcctgacaca ttctcatttc atcataccta
     3661 tttttttaac tgttggctat aggactttag atgtaagatc gtttgttgaa atctaaaata
     3721 cacaaagaga aaaagatcta gagtgtatca tcagtaagat gaactctcta gatctttcag
     3781 tcagactacg cttgttctac tttgacgatt ttaactaaca tatcgccacc tggagtagca
     3841 atagttactt catcattttt acgtttgcca atcaatgctt gcgcaatagg agaatcattg
     3901 gaaattttgc cagaaaacgg atctgcttca gcgcttccga caatcgtgta ctcttcttct
     3961 tctccatctg gtagttcgat gaatgtaact gttttaccaa ttgatacctc atctgcatct
     4021 acaccgtcgt tatcgatgat ttgagcaaaa cgaatcatat tttcaattgt tgtgattctt
     4081 ccttcaacaa atgcttgttc atctttcgct gattcatatt cagagttttc ggaaagatct
     4141 ccgaaaccgc gggcaatttt gattcgttca atgatttctc cgcgtttgac tgtttttagt
     4201 tcttctaatt ctttttctaa tttttcttta ccttctagag tcattggata aactttctct
     4261 accatgtgta acgtctcctt ttttcgataa aataccgcaa aaggtaatct tttgaggaat
     4321 atagtccaaa aaagattacc acgcttttct tcaaatgtaa atgtttttct aaaaatgatc
     4381 aatgtctaga gcctgttttt ctaagaatta tttacatatt tttccactaa ttccatatgt
     4441 tcttcataag ttttagcgaa ataaacattt ccagtgctcg tatctgctac gaaataataa
     4501 tagtcatttt ctgctggttc taatactgcc ttgattgcct cttcgcttgg attgtcaaaa
     4561 ggtccaggtc catagccggt attggtatac aaattatatg gtgaatctac agctgtatct
     4621 tcatacgtca ctaattcttt gtgttcacct aatgcgtata aaacagagat atctgactga
     4681 agtggcatat ttgctttgat tcggttaaag aagacttgtg caatgttttt acgatcattt
     4741 tcttttacgc cttctttttc aactagagaa gctagagtta aaacttcttg tacagtcaaa
     4801 tttttctgct tgatagctga ataatagttt tgcatgaccg tattcgtctt gttcaccatt
     4861 tcaatcacta gatccttaag cgaagtactc gtgtaataat catatgtggc tgggaataag
     4921 taaccttcca aacggtattt tgtgttctca gctttagatg cactttccaa cagttctggg
     4981 aatttttggt gcaactcgtt aaagaaagtc tcatcattca ctaaatctaa aaattctttc
     5041 ttgtctttac cagttacctt cgctacccgt tcagcaatct gatcgatatc gtacccttct
     5101 ggaatggcaa ttttcccatc tgcaactttt gttggctcag aagtaccgcc ttcttgcaac
     5161 tgtttgccaa tctcgtcaag agtcatatta ggcgctaact gataatagcc agcttgaaag
     5221 ccagttaaat ttttaaattt tgtataataa ttgaaaacaa tcccgctttt aataatattg
     5281 tccttctcca aaatctcacc aatctgcttg ttagaagagc cactcgggat ctcgacttgg
     5341 actaattggt catctgattt atctaaaggc ttcaacccgc tatctacata acgatacacg
     5401 gtaaatccaa gaaatccgcc aataatcaat aatgtaagag caatcactaa aatgatcttc
     5461 ctcacaatct tatcttcttt tttacgcaga tttctccgct tgtcgattat atctgctgta
     5521 gctgccttac tggcttcttt tttatcttta cttgggtgtt gtttgtttcc tgacaaaaca
     5581 actcctcctt actatcaagt tcgtaacttt attcattata catgatattt gaattggcgt
     5641 gaatgatttt atttaaatat tctatcaaaa atgtaagtag taaatccatt actataagat
     5701 taaaataaat gttatcaaga tacaagctat tttagcttta ttctttctgt aaaaaagaaa
     5761 ggagactaaa taaactatta tgaaaaaagg aaaacatgct aaaaaaagaa aatattcatt
     5821 tttaatgatc gttgtcgtgt tgtttagcct tagtgcgttc tctacaggaa ctattcttgg
     5881 atggcaattt tacaataatg aacactctca gatagttgcc catgctcaat cagctcaaaa
     5941 aaagttgata ctgactacca atgaacaaca gctcgttgaa aaaatcgatc aactattaag
     6001 aaaaaatgat tatattggct caatttacgt aaagaaaaat aatcgcatca tcatggaaaa
     6061 aggctatggc tatgcgaata aactcacgca acaaccaaat gatccttctc tttattatca
     6121 gattggttcg gttcaaaaag cattgactac tcttttgatt ttaaaacaag tcgagcgtgg
     6181 gcacctttct ttagatacta agctggctca attctatcca caaattgctg gcagccagca
     6241 aattactatc cgtgacttgc tgtatatgcg ctcaggcttg caccgaactg cttctccaac
     6301 cataccgatg actgatgaag aagtcgttca atttgcgatt cagcacttaa aatttacaga
     6361 ttatcagacc tctcattatg attcattgaa ctttaccata ttgactggaa ttttgatcaa
     6421 attaacaaat caaccgtatg aaaaattatt gaccgatgat atcatcgaac ctttaggatt
     6481 acagcataca aaattttatg accaagtcaa aaattcatcc aatcatgcac tatcctatca
     6541 aatgtctaaa gaggatgatt actttaaacc actgacagaa tctgaaacag agatccataa
     6601 cgaattaggg actggtaata tcagtatgtc cgtctatgat ttaaatacgc tgtttacaca
     6661 agttttatct ggaaaactag tttccaaaga cttactcttc tcattatggc gtgaaaatgc
     6721 gaatggacat ccatatagtg gtggggtata tagcggagat aattatatcc tgtcgcaagg
     6781 aaatatcgac tcttttgata catctgctat atttagcaaa gattcacagg atgctatcat
     6841 catggaaagc aatataaaag ctgacaaaac tatcaaactg cctactgctg atctaagaaa
     6901 ccaaatctat gacctgatgg aaggaactac taagttggca aatagctgat atgatgaaaa
     6961 gatagcaaat actacttctt tgaatagcat ttgcttaaaa aaagtactcg actaaacgta
     7021 ggaaagagtg tgggacaaat ctaaaaatca atttttgcta cagactttaa ttccaaataa
     7081 acagaacaga aagaggtgtt cttctttctg ttctgtccaa attattctaa gatttctctt
     7141 taccaacatt atttgacaaa gggcctatta aatctaaaat agtatcttta gattgctaaa
     7201 atatgtgcta gcaaatcatt catggcttgt tcttattttt aattttatgc aataaaaaag
     7261 aagaacaatt agcgtgatta tagaaataaa taatgagatt ttagaaaaaa atgtgtatga
     7321 atacctgatt gttactttat ttattccact ttcacttttt actgtaacaa aaggacctcc
     7381 ttgttttagt actgtagcat tttttgaatt aacagtaacc gttaatcctt tataccggaa
     7441 tacaggtaaa actattgttt tgccttttga agatttaagc gtaaatgtaa tttcatcttt
     7501 atttggagaa aagctactat aaataacttg accatcttct gtaacttgat ggtttttcaa
     7561 aagcaattga tcttttttat agcctatagg tacataatca aaattctcaa attcttcaag
     7621 tttattttcc atttgttcat tagaataagt tccttgaaaa ttcatttctt tcaccatgtt
     7681 aactactgat gaataattta aaattgaaat agctaatatt aataatagta taaaatttct
     7741 tctccttgta taagaaaatt tttccaactg tggagaaata aatagagata ctgaaaaaga
     7801 tatgaacaat gttgaaaata tcataaaacg ccaaggagct tgaataatat ttaaaggagt
     7861 attttgtaag gcaaaccatg gaaatatttt tgtacaaagt agaatagata ttatacccat
     7921 tatataagtg attttagata agattcctaa ttttttaaag ttaaatgtta gtataattaa
     7981 acaaataagc aaagttaagc caataccaaa tgatagtaat tctgaatcta tacttccaat
     8041 caaaaactct ttacccagat aaattgctct tttttgtaat atatccacat aaggtctatt
     8101 cagatcttga tacaatgtct gctcaatcat aggacctata aacgctagtg aaagaagtaa
     8161 agtaactata gcagctttta ttaatttaat aattaagaag atttctattt tctttttccg
     8221 ataaaattga ataattaaag caattataat cattaccata gtcatagcta cagaaagaac
     8281 atgagtgtaa attaataaag tcatgctaat cgccaacata acccaagatt ctttttttga
     8341 gtcgtaaagc tttataaacc cgagtaaaat aagaggaagt attgacattg cgagtaattc
     8401 ccccattgcc cctcgaagaa atatttctac actcctaaaa gaagatgttg tatatataat
     8461 agcgaaaaag gagctagtaa catgtttttt ggtaatttca tacattacat aatgacatat
     8521 aaatagagta atgagcgtaa caatataaag aaaaaggtta tagcctattg ctaaattagt
     8581 aaacttgatc aataaaaata aaggatatag agttaaccat gggtaaaaat tatttacttg
     8641 catgccatat gatctaaacg tttcaaaatt aataggggag ctaaaaatag attctaaact
     8701 taacgcacga ttaatgtgaa atgccgtatc ataaaagcca aatatttcca tgtttttaaa
     8761 tgctggaaat aaatataata aactaacaaa tgcataaact ataaatattt ttacagaaaa
     8821 aatttttttc aaattcatat accacctcat gtttttttat attacatata gtatcattta
     8881 tttttttaaa acactagatt agtcactata taaaatgtga ttaattttat tattaataaa
     8941 atatttttta tattacaaaa gtagtgttt
//
LOCUS       DAFBSV010000102         8339 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.105, whole genome shotgun sequence.
ACCESSION   DAFBSV010000102 DAFBSV010000000
VERSION     DAFBSV010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8339
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.105"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(75..605)
                     /locus_tag="LLB18_002458"
     CDS             complement(75..605)
                     /locus_tag="LLB18_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBK5245435.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            complement(787..1443)
                     /locus_tag="LLB18_002459"
     CDS             complement(787..1443)
                     /locus_tag="LLB18_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HBK5245436.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            complement(1570..2043)
                     /gene="dfrF"
                     /locus_tag="LLB18_002460"
     CDS             complement(1570..2043)
                     /gene="dfrF"
                     /locus_tag="LLB18_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HBK5245437.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            complement(2462..2680)
                     /locus_tag="LLB18_002461"
                     /pseudo
     CDS             complement(2462..2680)
                     /locus_tag="LLB18_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2711..3925)
                     /locus_tag="LLB18_002462"
     CDS             complement(2711..3925)
                     /locus_tag="LLB18_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HBK5245438.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(4266..4508)
                     /locus_tag="LLB18_002463"
     CDS             complement(4266..4508)
                     /locus_tag="LLB18_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBK5245439.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(4540..5097)
                     /locus_tag="LLB18_002464"
     CDS             complement(4540..5097)
                     /locus_tag="LLB18_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBK5245440.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(5110..5298)
                     /locus_tag="LLB18_002465"
     CDS             complement(5110..5298)
                     /locus_tag="LLB18_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBK5245441.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(5311..5877)
                     /gene="amaP"
                     /locus_tag="LLB18_002466"
     CDS             complement(5311..5877)
                     /gene="amaP"
                     /locus_tag="LLB18_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBK5245442.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            6294..6467
                     /locus_tag="LLB18_002467"
     CDS             6294..6467
                     /locus_tag="LLB18_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245443.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            7107..7580
                     /locus_tag="LLB18_002468"
     CDS             7107..7580
                     /locus_tag="LLB18_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBK5245444.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            7589..7816
                     /locus_tag="LLB18_002469"
     CDS             7589..7816
                     /locus_tag="LLB18_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5245445.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT         2551 a         1633 c         1227 g         2928 t
ORIGIN      
        1 aaaatcttaa ggattttccc gccaacgtgg tcggatcgct ccgtcggttt aacagctttt
       61 ctgtttctct ctagttatct acgcatataa atcaaatcgg ttattccgtt ataagtctgt
      121 gttttacaaa gccttaactt tatttccctg tctatgttgc ccaaaagacg aaccccattt
      181 cctaacagag taggaataac agaaatgtaa tatttatcaa tcatattttt gcttaccaac
      241 tgctgaacaa gatttgctcc gccacaaatc caaatatcct ttcctgcttc ttgttttagc
      301 cgttccaata ataaaacagg attttcactt gtaaaatgaa tttgttggga agaattgcac
      361 tctttatgtg ttaatacata agttgtaaat ttattatata cccattcttg cggagaaagt
      421 tcagtaacaa cctgatgaga agtattccac cccattaaga cagtatctat atctttggta
      481 aattctgtat aagtgtcgat gttttcattg tcatttccat gaccatttag ccaagctact
      541 ccaccattac cgtccgcaat atatccgtca aggctcatgg caataaataa aactactttt
      601 ctcatttttt ctcttttata aatacaaaca ggaatttatt tctctttttt actcataagg
      661 gaacaactga ttgctacaaa taaacccatt aaaatccatg gaaatgctgc tcttataaaa
      721 tcactaacca tactttattc ctccttaaat tccaatttcc ttagttctac aaactgaaat
      781 ttttgcctat gaatgtatct tgttctttat acgcaaacag gcttctgtgt gcataatcca
      841 atgtcttgaa aacggcattt gaattagtcc acaaatatct ttattacacc aataatcaat
      901 cagccaaatt gctttttcat tgtcgtttac tacattcaac gattctaagt atccttttct
      961 ttctttcggt atttttcttt tcaattcatc ataagataac cgttcaagca ttttctcagt
     1021 gctttcccat acttcgaaaa tatataaata taattcttcc agattaagct gttttgaaaa
     1081 gtctgcaatc tgctgtttca tgagttcatt tcctgttgta atgataggtg aattgatacg
     1141 ctcttgataa ttgcctgcaa aaaatacttg ttcatcttca tttatcactg tatgcacaac
     1201 tatatcttca atgcggaaaa tatgccaaat agaataagca atcgtcttac tatgataacc
     1261 atcagcgttt atgaagggga ttgagttaaa atcttctctg cataattctt ctttgaaaga
     1321 tactaaggtt tgtattaact gacttcgtaa agtaagtaaa gtatcaatac ccctcttata
     1381 agtatctttc ttttttattt gtgcctgcat tgttttatta agttcagacc attccttatt
     1441 catattcaat cctctctcaa attctgattt tatcgcccca tacaaactgg aatttgtctt
     1501 acaacaattt atatatgcat aaaaagcaat atatttatga aaacacccta aatccaaaat
     1561 ttactcaatt cattttttcc ttacataaaa tgttctcgta tatttcactt cctcaccaag
     1621 tgtttcccct atcaaaactt caaaatcatt gatatcaaat tctggaaaga atgtatctcc
     1681 atcttcaata tttaaatcta cttctgtgat atacatttta tctactattt gcaaagcttc
     1741 cttaaatagt ccatatccac cagatatgta tacatctcgt cctttagcca ataataatgc
     1801 atcttctaat gatttaactg aaactaaatt atctccttga tactctgttg tggtggaaac
     1861 aacaatattc attctattag gcaacggatg accgatttct tcataagact ttcgccccat
     1921 aataaccaca ttacccgttg ttaactctct aaattgcttt tgttctccct ttattttcca
     1981 tggtatatta ccattcttgc ctataacatt attctttgac ctcgcaacaa tcaaacctat
     2041 catctatttc atcctccata atatgatgtc gtacctgtga ttccatcaag tgcaccacat
     2101 cttaacaaac tcaaaattat ctcgaactaa ccagctcgac aaattccttt tttgtcttca
     2161 tctgcattat atcatattgt tataagcatt gccatttctt ttctgctttt gaaaagttac
     2221 ttatcagcct atgttttgta aagggtgata ttcagcattt ctcacgcaac aagcccttga
     2281 caaaccatag actaataagt tttaaggtaa tcaagcagaa atgaaatagt ctgctgtttc
     2341 acggcaacaa aaaagagata ccaacacact tatgtagtat ctcttagtct agtagcaata
     2401 ttcttttgtt tgcaagcagg taaacatggg ctgtttctta atatcttttt gtttgggaaa
     2461 cacctttttc ccatcctttc accgttgcca tctctgctgc gcacaatgcc acagggataa
     2521 accatagcaa accgcctaat aacaagaaaa atactaagct gaagcctgag gtcgcgaatg
     2581 tgggatattc atataatgaa acgaccattg agatggtcat agccaaaaag ccaaagaacg
     2641 ttaatttttt tgcaggaatt ttcgttttgc tttgttgcat gaatcttcct cttttctatt
     2701 tgaatttgtt tcaattgagt ttgttgccaa agaagaaaaa gtccaatcct tcttcttgtt
     2761 cttcttttgt agtagtgatc gttgtaaagt gcatcgccga ttttaaaatc actgttgtca
     2821 gcacataggc atacacggca gtaatgatga caccaatcac ttgaatccct aagaagtacc
     2881 agctgcttgg attcgttagt aaatggctgt tagatgcaaa gatccctatc agaatcgtac
     2941 ctgtgaatcc gcccatgcca tgaacacccc acacatcaag tgcatcatcc cattgtttct
     3001 ttttacgaaa atcaacagca gcatgacaga cgatacccgc aatgatccca atcagcatgg
     3061 cactttttgc ttctacataa ccggcacaag gcgtaatggc tgccaatcca gcaacggatc
     3121 ctgttagtac gtcgacaaaa tcaaagccat ttccttttac ttttgcaatg atcagccaag
     3181 taatcatcgc aaatgcaaga gcgatgaatg ttgaaccaaa tgcattgact gcttgttcat
     3241 ctgctcgaag tgcaccaccg gaattaaaac cgaaccagcc aaaccaaagc agtcctgtac
     3301 cgatagcagc tgccataaga ctgctatgct gacttctttc tcctaaagga atctttcttt
     3361 gaccaagtgt gaggatacat gctaaagagc cgaatccagc tgtcgtgtgg atgactgctc
     3421 caccagcgaa atctctaaat cccatctgat ccaaaaatcc gccaccccat atccagtggc
     3481 aaacagggaa ataaatcagc agattccaaa aaataacaag tataatatag ccttttaaat
     3541 tcaatctccc tgcaaaagct cctgtcatca aaggaacggt aatcacgata aacatcagtt
     3601 ggtaaagaaa gaacattaaa aatggaatcg ttgcaccatg aaacatgttg gggaagcttg
     3661 taacatgtct catcaaaaag aaatctgccg ggtttccaat aacaccgccg atatcccgtc
     3721 caaaggccaa tccgaatcca ccaaataccc acataatcgt tgttatccca acggagagaa
     3781 aagattgaga catgatcgtt agtatattat tcttccgtgc taatccgccg taaaaaaaag
     3841 ctagaccagg agtcatcagg caaaccattg ctgtacataa aatcatgaat gctgtgtctc
     3901 ctgtattgat aggtaatgta ttcatttttt tcgcctcctt tctacgatta cgagtataaa
     3961 agaaggtgta gttgtttttt tcttctgttt ttttgaatta atacttgcat ttataaaaga
     4021 cagacaatta ataaaagctt gatgtgttgt gctctttttc gtttttcaca caaataaaga
     4081 caaaaaataa acggtcttct ttttatagaa aaccgtttat tttcgtcttt ttttattttt
     4141 aaagatattt tttcataagg aataaagaat acttcatata aaatatataa aaaagaaccg
     4201 cagcgagtgt cgctacggtt ctcaaatttg ttcttcattt caacataagt ttttcttcaa
     4261 tttgcttata atttacgtgc aaagaatgaa acgactaata ctaaaatgat tgcaccgatc
     4321 aatgatggaa tgatagccat tcctgcaatt gttggtcccc aagttcctag taaagcttgt
     4381 ccaattgctg aacctactaa accagcaatg atgtttgcga tgatccccat tgatgatcct
     4441 ttattcgtga ttgctcctgc aattgctcca atgataccgc cgacgattaa tgcccaaata
     4501 aatcccattt taaattcctc ctaactgact tcttacttct tattgtacac gtggttcgtt
     4561 attttctttg actttttgtg cacctttgcc tacagcagat tttgctttat ctgtttggcg
     4621 tgaagcaaat tgtcctgtgg attttgctgc ttctgttact ttgtcttgta ctgtttcttg
     4681 atctttttgg tattcttctt gtgttttgat gtctgcaaca ttcacattca cttcgataac
     4741 atctaaatgt gtcatattgt ttacttcagt actgatcaat tctttgattt ggttgtaaat
     4801 atcttcgatg tctttaccgt attctacgat cacatctaga tccacagcta cttgtttctt
     4861 acctacttct gtattgatac ctgctgttac gttatctgtg ttgactaatt tttcagccat
     4921 atttgagaaa aatccgccat ctaatgtcaa tagaccatct acatctttca atgcataacc
     4981 gatgattttt tggatgactt tgtcttcata agtcaattca ccattcatca tgcggttttc
     5041 tcctttttca tttgccaaaa ctgatccatt tgttgtattc atgtttttgt tttccatctt
     5101 tgtttcctcc tatgatttaa aaaattgatc aactattcct gactgtttca aataaaaacc
     5161 gattcctgcg ccaattgctg tcatgattat gatcaacaat gtcttgaaaa atccaatcgt
     5221 taaccataaa acagctagca gtagtccaag acccccaaag ataataggga gcttgtatgc
     5281 tgaaaatagt tctttcatta tttggccctc ctattccact cgagagtgct tgtagtctct
     5341 tgtatcttct tgttcttcat aaccgctgta tgtgactgcc actttgaccg tttcttttgt
     5401 tccgagtact ttagttactt cttcttcgat atcttgcatc aatacacctg ttttccctac
     5461 taatgaagaa gttcgtttca agtctccgtt gacatggata tggattcgat ttttcgttga
     5521 acgtatccgt actttaggtg aatgaatgaa ctcttcttcg tgtaaatggg aacgtaccaa
     5581 cccttcgatc gcttttttgt cgattgttag tttgccatct tcccgtttca taacgaaagt
     5641 tcctcttgac tttggataga aaagaacgac tagcaagatg ataatagcaa gaacggcaaa
     5701 tactacagct gcccagaaaa tatattgttg catgtagtaa ttcgttaaag taaagaagcg
     5761 aaatcgttcc aattgttcag gcataatata cggcgcattg atcaacgcaa tcgctagaaa
     5821 tactgaaagt agcagtaaac tcatgataac accgattatt tttaacccct tattcatttt
     5881 ccacctccta taaacttatt tttaccctgt aaataactct accgacaatc acagtataga
     5941 tagcgaacag ttagcatagc atcagtaaat aaagcgctac caaacattgc tggatcataa
     6001 cggcgtttta ttgccagtct gatactgaaa taacaattgc ttacttattc tctatttact
     6061 tttgattgct ggctatactt aaaggatatt attcaagatt aaaaattgca aagattatgc
     6121 tcagttatta ttacaagatt ctatttattt attaaatttt ttcggagaat taaaaaatac
     6181 aataaataac tttagttact ttaatgcgtt cttactttat ttttatatta tcatttttct
     6241 tattcacttc tttggtttat actattctta taaataaaaa cgaggtatgt cctatgatga
     6301 aaagattgta ctattcattg atcataacga ttggctattt gattgtatca aatctaggaa
     6361 atatggtatt tggtatcagt aaagaattca gttggactac tacattatgg gaatctctat
     6421 tctttttcat cttcgtattt ttgttacaaa attatcgaaa aaaataaaca tgtgccatct
     6481 atctgttggc acatgtttta ggatttatgg tactttttat tcggcaatcc attttatttt
     6541 tctacttctt cttaatacct ctaacacttt tgatttataa actaatccaa tgcatctact
     6601 tgcgcttatt aagctatttc agctagatag taccacccca tgcgtcaatg cttgattttc
     6661 cttttgtata acattgtata agcaataaag gacaaataag tggtgattac accaaaccat
     6721 tgaataagaa aaattctgat acgtaaataa acatgaactt gaaaaaatta atgaatcggt
     6781 tagctactac gtagttgtct tttttctcat acagttctgt taacttacac ttctcttcgc
     6841 tagataataa aaaatcctcc aactgtattg tccaatataa tcccaggcat ctaaactagc
     6901 attatagaag agacacacat agaatctaaa ataactggtt ttaaatgttt cttacaatca
     6961 aaaaaagctg ttaaatgcac tccacacctt catactctat cattttttat aaacgatata
     7021 tttttattgt ttttcgataa aaaatagttg ttttacaata attattctgc tatattttag
     7081 ctatcaaaga taaaagaggg ataaaaatga aatttaaaac attgctatta aaatttgtcg
     7141 ttttaggtat aagtgccgta tttattttgt tcggcgtact tttttatact cagatcgcta
     7201 caagcgaaaa aggattcaat tttgattggc agaccacatt atttgtttct gtcatttact
     7261 ttgcccttct cctagggatc gttattgctt atttcttatt gaaactattg aaaaaaatcg
     7321 aagataacca agctttttcc actcaaagct taaacatact aaaaaaaatc gaacgaacca
     7381 ttttgtttat tggtttcgcc ttttttggct tacttcctaa atttatgaaa gtagcggatt
     7441 tagacgatgc tccaggtttg atgttggtag gaatcgctgt cgtattcatt ccttttgcag
     7501 tatacacatt aacaagcgtg ctggaaaaac tgcttgaaca tgcgatttta cttaagacag
     7561 atcatgattt gacagtgtga ggtgcgacat ggcaattatc gttaatttag atgtagtatt
     7621 agctcaaaaa aaaatgagtg tgactgaatt gagtgagaaa gtgggcatta cgatggcaaa
     7681 catctctatt ctaaaaaatg gaaaagcaaa agccatccgt ttttccactc tcgaaaaaat
     7741 ctgccaagtt ttggagtgtc aaccaggtga tttgttgacc tataaaaatg actcgaatac
     7801 tataccagaa gaataaaata aagtagaaca aacagtaaat aaaaaataat ctgaatgata
     7861 gatgtgtgag acttttagaa gttatttacg tctattattc agatttttta tttcgattga
     7921 ataccgtttt atctataaat aagatatgta ctgactcata caaagggggc cttttcttct
     7981 ccatgtacta tcacttttcc tgatacaact ggtttcctgt tacgttgtag ttggatctgc
     8041 ttttagtata atactttatt cattccacca gactgatagc agtttgagca gtctaaataa
     8101 tcatgtagta ttacaggcca ttctgtttca taccttgaag tgcttaaaac ttcagctaat
     8161 ggcccattgt gttaactctt actccattct tttttagtaa gctcccatat atactgtaaa
     8221 gccttctata tattatgtca tgttgctttt taacatttac tatgtagttt tgataaaatg
     8281 atttgaataa cagtgatgga caattctttt ttatttttaa cattattttg ataataatg
//
LOCUS       DAFBSV010000103         8282 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.106, whole genome shotgun sequence.
ACCESSION   DAFBSV010000103 DAFBSV010000000
VERSION     DAFBSV010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.106"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(365..1156)
                     /gene="msrA"
                     /locus_tag="LLB18_002470"
     CDS             complement(365..1156)
                     /gene="msrA"
                     /locus_tag="LLB18_002470"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBK5245446.1"
                     /translation="MLDVEQMEIDLYNIILNRNTREWERTQFEEAKEDLAKMSIKQVI
                     EKLEVNLRPLALRDNLTPDAMDFYLRITGESASAKAYDYAKHKITSPLYQERAIFAGG
                     CFWCMVEPFETKPGVISVLSGYTGGETKKPNYDQVSGGYTGHVEAVEIIFDTRQITYE
                     ELLEIYWQISDPTDAFGQFQDRGKQYRSILFVVNEKQRQLAEKSREQLIQSNRFSRPI
                     VTEIRQAKTFWPAENHHQQFYQKQPKRYKKIKHSHQLHLFFQRHR"
     gene            complement(1347..1982)
                     /locus_tag="LLB18_002471"
     CDS             complement(1347..1982)
                     /locus_tag="LLB18_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBK5245447.1"
                     /translation="MIFLQKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFIGTSKTLAILAVATVGLYGIGDCIFT
                     GLFSINTNESSWNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYRLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            complement(2248..3300)
                     /locus_tag="LLB18_002472"
     CDS             complement(2248..3300)
                     /locus_tag="LLB18_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK5245448.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            complement(3313..4251)
                     /locus_tag="LLB18_002473"
     CDS             complement(3313..4251)
                     /locus_tag="LLB18_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBK5245449.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            complement(4702..5352)
                     /locus_tag="LLB18_002474"
     CDS             complement(4702..5352)
                     /locus_tag="LLB18_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245450.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            complement(5452..5961)
                     /locus_tag="LLB18_002475"
     CDS             complement(5452..5961)
                     /locus_tag="LLB18_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HBK5245451.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            complement(6046..6525)
                     /gene="rlmH"
                     /locus_tag="LLB18_002476"
     CDS             complement(6046..6525)
                     /gene="rlmH"
                     /locus_tag="LLB18_002476"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBK5245452.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            6953..8242
                     /locus_tag="LLB18_002477"
     CDS             6953..8242
                     /locus_tag="LLB18_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBK5245453.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENIKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
BASE COUNT         2628 a         1681 c         1326 g         2647 t
ORIGIN      
        1 tagttattgt ttgcgctttt atacggaatt tagttcatca ttaatgtgga attcgattag
       61 gtgtctatta attatcaaga tgattctcta caaaattcca tagaaaaatc aagattctac
      121 aattcgaatt ctctttcaca tggaaataaa ggctagtaaa aaaacaggag ttgtgacaaa
      181 agacttgtca tacctcctgt ttccttgcga cttgaagctg aatgctttgc gccacaacct
      241 tttcctcggt gttctcaaag caactcctcg aaataattca taactgtcca aaaatatgaa
      301 aagctatttt tgtcagttgc tcattatttt gtcggagctg aacgctttgc gccacaacct
      361 tcctctatct atgtcgctga aaaaataaat gaagctgatg cgaatgcttg atctttttat
      421 atcttttagg ttgcttctga taaaattgtt gatgatgatt ttcagctggc caaaaagtct
      481 ttgcttggcg aatctctgta acgataggac ggctaaatcg gttagattga atcagttgtt
      541 ctcttgattt ttcagccaat tgcctttgct tttcattaac aacaaataga attgaacgat
      601 attgtttccc ccgatcttga aattgaccaa aggcatctgt agggtctgaa atttgccaat
      661 aaatctccaa cagctcttca taggttattt gacgtgtatc aaatatgatc tcaacagctt
      721 caacatgccc agtatatcca ccactgactt gatcgtaatt tggttttttg gtctctccac
      781 ctgtataacc agataacact gagattacac ctggttttgt ttcaaaaggc tcaaccatac
      841 accagaaaca gccaccggca aaaatcgccc gttcttggta taagggtgaa gttatcttat
      901 gtttggcata atcataagcc tttgcactcg ctgactcccc tgtgattctt aaataaaaat
      961 ccatcgcatc tggtgtcaaa ttatctcgta gtgctagcgg acgcaagttg acctctagtt
     1021 tttctatcac ctgctttatc gacatttttg ctaggtcttc ttttgcctct tcaaattgtg
     1081 ttctttccca ttctcttgta tttcgattta aaataatatt ataaaggtct atttccatct
     1141 gctccacatc taacatgaag tcaccctctt tcaagttttc ttcttattca ttcaaaaaat
     1201 gactacctga aatttagcac aacgcataac aagttaagac taacttgctt ttcgctctcc
     1261 tcatctctat tcttagtcga acacatccac acgaatggtt acccatagag aaattctttt
     1321 acttaatcag cttcacactg ctttttctac tttcgtagtt gaaaaaaact taaacaaatc
     1381 atcggcaaat agttaaagaa aaaacttaag cgttgaaaga agcccaattg cttaaagaag
     1441 gcaaactgac taatcgacgg aatccgtgct aatctgtaaa gacctgcaat tagtaaacta
     1501 ataactgtta aaacaagata aaaatggcta agcgtacctt gaccactttg acgataaagc
     1561 agaacaagta acaatgggaa aagtagaaag cctgcatagc ctagcccaga acctatatta
     1621 tggatccaag tcgatagatt ccaagagctt tcattcgtat tgatactgaa taacccagta
     1681 aaaatacaat cacctatccc atataaacca actgttgcaa cagcaagtat tgcaagtgtt
     1741 tttgatgttc caataaatag gtgatacaac gcaggcaacg aaagaacaaa aaaaagtcca
     1801 gatacaactg accagaccaa gaaagcacgt ctgactggac tatctacgtc accaaacaca
     1861 ctaattacgg tagtcatttg attcagtttg ggataaaaaa ggccaaggat atacggtgtc
     1921 gataaatcac taatcacacc taataataaa aaataaaaac catatttttg caaaaaaatc
     1981 attttcttct cctacttttt agtgattatt cgatacatcc aacaatcaaa ttttttctca
     2041 ttttaacaca tatttttatt ctagttgcct tttgaacaat caataacata aaggtgagtt
     2101 tcttctacat tttaaaaaat cgaatggcac tgaagagttc agttgtcagc atcaatctcc
     2161 tactcaaaaa ggcaaaaaaa cgtaagtcag atgttgttga catctcactt acgcatccat
     2221 tgattgaaaa tttcttagta aaatctacta gcctaaaaat ttgaagactt cttctcgatc
     2281 atacagttta aatactttct cgcataaaaa ttgagtaatt agtgccgcaa aaacagggat
     2341 gactaaccaa caaagaacaa caagaaagcc atttagccct gcatctaaag aagccaacgg
     2401 accaacaagt ccgaccacgc cgaaaccagc agaagcaggc gtacctgaaa tagaaaatag
     2461 agcgacagga atagctgtaa tcactgcact aactaaacaa ggaataagaa tcacaggttt
     2521 tctaaataga ttaggcatca tcatcttcat agcgcctaaa gcaatcgcaa ttgtcacacc
     2581 tgacttatta accttccaag agttcactac taaaacaaaa gtggttgcag ctacgcccat
     2641 cgcagccgca ccagcagaaa caccatctag ttggattgcc attccgattg ctactgttga
     2701 aataggagag ataatcaaaa aggcaaagga acaaccaatc aagatagaca ttaacagcgg
     2761 ttgtaaggta gtgaagttat taatcaatga tccaattgca gaagtaattg ctgttacaaa
     2821 agggaataaa taaaaaccaa gtaaacctgc acctacacct acaacaatcg gtgttaacac
     2881 aatcgacact gacccaaaac tatttccaat cagtaaaatc agcccgacag caatcgatgc
     2941 tgtcagcatc gtattaataa tatcgcctgt accagcacca acgtaaacac ccgtttcacc
     3001 caaatcaggt gtgaatttga ctacaccaga accaacaaaa gaagctccgg ctacaaccat
     3061 cattctcatc ggatcaaatc caaattgtaa ggcaatcaaa ccaccaatga tcaaaggtgt
     3121 tgctagttga aaaataactg ctaactgtgc gatcgttacc gcaaagggat acgcactaaa
     3181 atattttaaa atggcaccta atactgcatt aggaatcaat ccaataatga ttcctgttgc
     3241 tgtaccagcg aggactttat tcagaaaaat tttcggtgat attttttgtg aagtttccat
     3301 tcaatctctc ctttatttta cgttcaaact atcttctttt gcatggacaa gctcagtcaa
     3361 gaaatcacaa taaggcgtcg caacaccata tttcttccct tttctagaaa ttgcgccatt
     3421 gatataatcg atttctgtta atcgatggtt cttaatcaag tcttgataca ttgaaggata
     3481 atgtaaccca attgtttccg ggtcaaaaca agattcacaa tgtgcaatga cttctgggac
     3541 atctagttca atcttctcta ctgctgctac tttggcaaac tcattgacaa tcgtcgccac
     3601 cattttatga gcagtcgatg tttttcctag ctcagccata ttaacgtcta agattgtgca
     3661 tagtccgttc attgttccgt tcacacatgc tttgcgataa atagaatagt gaatattgtc
     3721 agaaaaatga gcatttaatc ctgattcaga caatttgtct gctaattttt ttgcagctgc
     3781 ttcttttcca tcacctaaat tttgtaattc tactgaacca cttccaaata atttgacctg
     3841 accaggacct tcaagacctg ccgtccacat ggtatttcca atatagatat tttccattgg
     3901 tacaaatttc tcaataatat cttcatgccc gataccattt aatagacata agacctctgt
     3961 atcttttttg attaatgatt ggatatcctg cagcattttt tccagctgca tcgctttggt
     4021 aaatagaata atcagatcaa cttgatcttc tttttctact tcggattgaa gaacgattgg
     4081 tagttttgct tctacctctt taccattaaa atttgcttgt aatccatgct ctttgatttg
     4141 ttggacatgt tctgcccagc catcgattaa taatacttcg ttcccacttt ggtgaagcat
     4201 taacccaaag cgacttccca ttgcgccagc gcctgcaatt gctattttca ttgattcttc
     4261 ctcctttttc tttctattat attcatttga gaatcatttc acaaccttgt tttgttattc
     4321 ttctcttatt tatcatgttt atatccacca ttcaagttat tttatcagca aatcaataaa
     4381 aactggaata gaatcccaat ttcatcgtaa gagaaactag actagcaata agaaaataga
     4441 aacattcata gaaaaaacct cactcctctg attataaaag agggggcatt aacctcgtgt
     4501 atactaaaac cttccattca ttcgatggat gattttcttt ttgtgaaaaa atattcattg
     4561 tagtacgatg ttgcgcaaca cagacggatg gtattgctta ttatttatta aaatcgaaca
     4621 atacacttat ttaaaaactt ctttcccaga ttttcttcca tttttacagt tataactagt
     4681 attatcatga aaaatagcct tttattgtct atgggaataa taatttaaaa ttggtacttt
     4741 tttattaatt agttcatcgc ccaataatct ctccagtttc ttagcatctc ctgactcaac
     4801 cggaattatc caagcccagt ccaaataatt ttttaaaatc tcatcatatt ttgcaaatat
     4861 ttcattgcca tattccgtcc ttaaaattat attttcagtg ccagacaagt gatttgtatt
     4921 gagttgataa aaaagatctc catctaaaaa aatatcatta gaagaagatt tccccacagt
     4981 aatgaccatt ccatcagctc tatgtgttac atacaaataa ttgtatgacc tcatttcacc
     5041 taatgaatca attatttctt gccctttagc tctaatatat tgatctctat tacctatctc
     5101 actcttattt aacaaaagtt ttttcatgtc aaatttaatc ggctgtttta tttttgtaaa
     5161 ttcgcttcta ctactaatcc aatccgagat taatttttca acatgtccca gagtaaactc
     5221 tgatttattc gctaaatact ttttttgttg tattaaagac atctttcccc gaagctcaaa
     5281 attgagccta catcgattct ctatctcttc aaaaagcatc ttatcttcat cattcttata
     5341 ttcatcattc ataaaaccaa tccagctcct cgattaagat aatattttaa tctcatacaa
     5401 aaactagctc tcatcaaaac aaccattgtt ttgatttctc atgaaatttc tttatacttt
     5461 tctccgatta taaattccta accccttgag aaaattacgc atatatttat ctccgcaagg
     5521 cttaaaattt cgttggcctt cttttctcaa aaatgccccg atttcgcctt ttgatggata
     5581 gatttctgcc tcagcaaaaa cgtctaaaat atcatcagtg gtcatagaca aggcgatttt
     5641 taattttttt agcaacacat tgttgatata tttgatttcc ttgctttttt gcggcgtgtc
     5701 tactatcggc ttatcttttt gcggaccacg cgccaagaga atcaggccat ttaggaatgc
     5761 gtcaaaaact tggttgttga tggttttttc atacacatta ttttctgcat tatctttgtt
     5821 cttatcctgt actttggtca gtaccgcctg agcttcttct ttagtcagtg gtacaccgcc
     5881 tagctcaaaa gctttaatca aatccgtatc tttcaaatca atcgcataac gcaatcgcaa
     5941 taacctatca ttgttattca tttgttcctc cgaagtattt agtctttact ttcttacgta
     6001 ctttttgtct tgctaagatt tttaggatca atgataaaaa ccgcatcact tatgataagg
     6061 cgcccccgca ttgatccgga aggcacggta gatttgctcg acaaggatca gacgcatcaa
     6121 ttgatgtgga tacgtcattt ttccaaaaga gatctgagca ttgcttcttt tcatgacggc
     6181 ttcgctgagt cctaaagagc cgccgataac aaaaacaagg tggctttttc cttggatacc
     6241 taattggtcg atttgtttag caaaagattc acttgtagga tttttccctt caattgctaa
     6301 ggcatagacg tattcttgtt ctttgatttt cgctaagatc cgttcccctt ctttttcttt
     6361 tacttgtctc atttgcgctt cgcttaaatt ctccggggct ttttcgtcag gaacttcgat
     6421 caattcgatt tttgcatagg cattcagccg tttgacatac tcattgatac cttggatcag
     6481 gtatttttct tttaattttc ctactgagat aattttgata ttcatgtttt ctctcctttg
     6541 gtcttcatgc tcactttgtt tattataatc aattttttcg tctatatgtt tattttggct
     6601 atttttgtta aaaagatttc cccaacagtt atgcacaaca tccacaggtt tatccacaga
     6661 aaacagtgtt attttacctt atttcatcac attcattagg caaacatacg ttttataaga
     6721 atttatccac tttatacaca ggctgtggat atgttttatc ccttattttt ccaatcctat
     6781 ccgcgtagtt ttacacagta tctgtggaaa aagaaaatca aatattttca tctgaaaaca
     6841 atgatttttc ctaaagtttt tcataaaaag ttcacagtct caaagtagac taaagtcaac
     6901 aaataagact atactaacag tagataaatg aatgtaattg gaggaggaac acatggatag
     6961 aaaaaatgtg acaccaaaga tgaaaaaaag taaaaataat agcctctggc gtaagttagg
     7021 tctggggctt gttggaggga tcgttggagg actactgaca gctggcattt tttatgcagc
     7081 gatgggcact ggcaacaata gttctactgc tacaagcggc aatcagaatt ctgccggtga
     7141 aacagttgtg gaaaatatca aagtcaatgt agattctgat atcaccaaag cggtagataa
     7201 agttcaagac gctgtcgttt ctgttatcaa cttacaaagt caaaaccaat caagcggttt
     7261 tggcggacta ttcgggcagc aagaagaaag tagcagctca gatgatagta atttggaagc
     7321 ttatagtgaa ggaagcggcg tgatctacaa aaaagacggg aatactgctt atgtagtcac
     7381 gaataatcac gtagtagatg gccagcaagg tcttgaagtc ttgatgaaag acggtacgaa
     7441 ggtaaaagct gaattagttg gaacagatgc ttattcagat ttagcggtgt tgaagatcaa
     7501 ttcagacaaa gtcgaaacag ttgcctcttt tggtgactca agtgctctga aggttggtga
     7561 gcctgcgatt gcgattggtt ccccactagg atctgaatat gcaaattctg tcacttcagg
     7621 aatcatttct tccttgaacc gacaagtgac aagtacgaat gaatcgaacg aaacagtcaa
     7681 tatcaatgcg atccaaacag atgcagcaat caaccctgga aattctggtg gtcctttagt
     7741 taatatcgaa ggacaagtta tcggtatcaa ctcaagtaag atcgcaagta cttctgaatc
     7801 tacttctaat gtaagcgtag aaggaatggg atttgctatt ccaagtaacg atgtagtgaa
     7861 tatcatcaat caactggaaa aagacggaaa agtgacacgt ccagctctag gtatcacaat
     7921 ggtcgactta tctgccgttt ctactcagca acaagaacaa atcttgaaga ttccttcatc
     7981 tgtaactaac ggtgtcatcg tgacaaatgt ccaaacagct acaccggctg aaaaagctgg
     8041 attgaaacaa tacgacgtca ttactaagat cgatgacaaa gaagtttctt ctggtgtaga
     8101 acttcaatct gctttgtata agaaaaaagt gggagattct gtcaaaatca cttactatga
     8161 aggctcgaaa gaaaaaacaa ctactgttga attgacgatc gatcaatcgg cattaaaaca
     8221 aaatcaaaat agtgaaaatt aataaaaaag aggttgtgac aaagacttgt cacaacctct
     8281 tt
//
LOCUS       DAFBSV010000104         8011 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.107, whole genome shotgun sequence.
ACCESSION   DAFBSV010000104 DAFBSV010000000
VERSION     DAFBSV010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8011
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.107"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(21..1052)
                     /locus_tag="LLB18_002478"
     CDS             complement(21..1052)
                     /locus_tag="LLB18_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5245454.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(1059..1889)
                     /locus_tag="LLB18_002479"
     CDS             complement(1059..1889)
                     /locus_tag="LLB18_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5245455.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(1886..2701)
                     /locus_tag="LLB18_002480"
     CDS             complement(1886..2701)
                     /locus_tag="LLB18_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBK5245456.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(2698..3522)
                     /locus_tag="LLB18_002481"
     CDS             complement(2698..3522)
                     /locus_tag="LLB18_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HBK5245457.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(3512..4612)
                     /locus_tag="LLB18_002482"
     CDS             complement(3512..4612)
                     /locus_tag="LLB18_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBK5245458.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            4790..5575
                     /locus_tag="LLB18_002483"
     CDS             4790..5575
                     /locus_tag="LLB18_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HBK5245459.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            5608..5991
                     /locus_tag="LLB18_002484"
     CDS             5608..5991
                     /locus_tag="LLB18_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBK5245460.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            6067..6198
                     /locus_tag="LLB18_002485"
     CDS             6067..6198
                     /locus_tag="LLB18_002485"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBK5245461.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            6167..6403
                     /locus_tag="LLB18_002486"
     CDS             6167..6403
                     /locus_tag="LLB18_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBK5245462.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(6481..7452)
                     /locus_tag="LLB18_002487"
     CDS             complement(6481..7452)
                     /locus_tag="LLB18_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBK5245463.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
BASE COUNT         2325 a         1881 c         1567 g         2238 t
ORIGIN      
        1 aaatgtttgc cgactataca ctagctttgt tgtgcaaaat gctgagtatc aatttccaca
       61 gggattgcta gaatatcttt cagctgaatg tataaggcat cgctaatttt ctcttcccga
      121 tcgttcaacc gatccactaa aatttctttg ccctccagcg tttgaaaaac ataccgttga
      181 atgttgccta aaataaatga ttccttccat agaaccggaa tcttaacccc ctgaggaacc
      241 ggttcaaatt gaatcagctc cggtcttaaa taataaatgc agcgattgcc cttagcggaa
      301 aactcgtggg tatactgatt cagctcatac cattcgaaac gattatagtt gccgataaat
      361 tccgcaacaa atcggctctg aggattctga tacaattcct tcgaggtgga aacctgagcc
      421 acccgcccag cttccatcac aaaaatccga tcactgattc gcatcgcctc ttcttggtca
      481 tgagtcacaa aaatcatcgt catccctagc gattgctgga tagcgcgcaa atcccgctgc
      541 agctgttttc taattcgggc atccaaagca cttaatggct catccagcag caggactttc
      601 ggttcagtga ccaatgagcg agccagtgcc acccgttgtc gttgaccgcc agaaagaaac
      661 tggacatttt tatctgcctg ctccgtcata tccaccaatg atagcatctc aaaaaccttt
      721 tcctgaatca cctcaggact cagcttcttt accttcaaac caaaggctac attttcaaaa
      781 acagtcatag ttggaaacaa tgcatactgt tgaaaaacaa agccgatatt gcgatccttc
      841 gtaggcttat cggcaatatt ctcattgtcc agcacaatct caccgctctt tggttgttcc
      901 aatcccgtga tacagcgcag caacgtagac tttccgcacc cgctgggacc tagtaaagta
      961 accagctcac ccttttcaat ctgaatttca tcaatagcta aaatctgttt ttcatcaaaa
     1021 aacagattga gatcatgtat ttctaaaaac attttccgtc acaactcctt taagggcttc
     1081 tttttcgact gcttctcttc cctcgtctgc ttaagggaca gctgttgctt ttgtcgataa
     1141 gtcagcataa aggtagttaa agcaattccc accataaaca gcaaatacaa aaccatcaca
     1201 gcgctagcca aatggccgtt ttcgttcatc cgccgcagca tatagatgcg taccgtctga
     1261 aatcgaccgc caatcaacag gttcgtcagc atgtactccc caaaaaccga agaaaaaatc
     1321 atcagagaaa ctagggtcac accgatacgg atgtttggaa acagcacctg gataataatc
     1381 gtagacatcg gggcgcccaa ggtttctgct gcatccacta attccttcag attaattaag
     1441 cgcatctggt tgttaagact aagatagaca atcggcaacg ccgtaataaa caatgcacct
     1501 accaacacta caaacattgg gataccagtt tcagcatacg ttcgaagcaa agccgttacc
     1561 aaaatcactc ctggtaaagc atacggcagc aggagcagct tttccagcca acgattcaaa
     1621 cgagggaaat acaaatgaat ccaaataatg gtgggaatca tcaacaacag aatcgtcacc
     1681 aagaccacac ctgctaataa aagtgagcga cccaccgcag caataaattc cctgtccgtc
     1741 agcagctgtt ggaaccattg caaggtaaaa tcactaggta aaagcgattt tgaccattta
     1801 gtggagctgg catacaaaat cgttccaata atcggcagca agtaatacag gacaaagcag
     1861 aacaaaatcg gttttattaa ctttttcacg tctgcaccac cttgcctttc ttttgaataa
     1921 tcaacattgc cgttaccagc aggacaccta aagcgactgc caacgcactg cctaaattag
     1981 gcttggcgaa cacatctccc gacactaaag ccgcaattcg aatcgttaaa agatttacat
     2041 tactgctggt cagggcatac gctgtttcat aggtccccat gccattagca aataagatga
     2101 caaaggtgct ggcaatcgat ggtcgcaaaa aaggcaaagc caccttgaac caagcatacg
     2161 ctgatgaagc gcccagcaat tgtgcggact ccagccattc ctttttcact tccttcatgc
     2221 tgggatacaa aaacaagacc cctaacggaa tttggaaata ggtatacgtg atggtcaatc
     2281 cccaccaaga atacaaattg aagtccgcta gaaatggcaa aatcattttc agcacaccta
     2341 cattccccaa caaaataata aaagagaatg ccagcggaat cccagcaaaa ttagctgcca
     2401 aattggaaac aaaggtgatt ttctcctgca atttagtcga tagattcatt aagcataaac
     2461 ataaaataaa cgtcccgatt aacccaatca cactggagct gacagcaatc agtacgctgt
     2521 taacaaaggc ctgtgtgtaa tatttgttgc tgaaaatatc actgtaattg gccaatgtcc
     2581 actggttagt taaatcactg tgcaagctgc acagaaccat aaaaagcagc ggcagcagta
     2641 aaaatgcaca gaagataaag gaggcaggaa ccagaaccaa gcgttttttc atctctttca
     2701 tcccctcatc aattcttgaa tgtcctgcat tttctctgac ggtgcaattc ctaataacca
     2761 gcaaaacaat ggagccgcca gcagctgtgg tacagtttgt tccttcagct tttggcgttt
     2821 atttgaaatc aaataaaaag gaacttcacg atgtgcagcc aagctgccgc catgcagtcc
     2881 gtgcgcatcc atcccgtgat ccgcagtcac cacgacttga taaccttttt gcagccattc
     2941 aggaaggtaa atagccaata atctgtccgc ctgattaacc gctgctgcat attcatgaga
     3001 atcggcggta aatttgtgac cgacatcatc aatattcatc gaatgtacga ccaaaaagtc
     3061 tggctgatac tgattcacta aataatgggc atccgcaaat aaatgcgaat cagggtaagt
     3121 gtcctcacta taaaagatgc catgctgaat cagtcgctcc tcctgatgct ggatgcgatc
     3181 aaccaaacga ttataggggg cttgattgta caactcgctg taccagtggt aagcggcggc
     3241 tcctgttttt ccgccagctt ccttaactaa ttcaaacagc gaccactctt tggatcgctg
     3301 agcatggtaa ttactataga tgccattttc ataggctgga acgccggtca tcagtacttc
     3361 gtataacgga cgtgaattgc tgggcagctc actttttacc ttcaataagc ttgcttgctg
     3421 gtgctcaact aaatgattca tgaacccaag ctgggcgacg gctgtgtcgt agcgacagcc
     3481 gtctagtata actacaatca gtttgtcaag tctactttgc ataggtcagt acctccgcct
     3541 gccaaagctc tggaagctct acagaggtct tgttccaagc ttcattgtct tcaactggca
     3601 ccgccgcttc ataagcatcc tccggcagta atttttcagc tacttcttta ggcagctcta
     3661 ccttgcgaat aggtcgcgca tagccctttg ccaaattgat ttgcccttca tcagataaaa
     3721 tatattcccg tgctagcttt gccgcattgg gatgaggggc atttttattg attaaggttg
     3781 tatacccgct aatgatggag ccgtctgttg gcacagttac ctcaaaacgc tcggagtcaa
     3841 tttggtcacg ataatttagt ccattgaagt cccaaacaac tgccacatcg atttcacctt
     3901 tttcaagatt tgctacgctg gcatcaacgg tggacaaacg gcctttttct gccatttttt
     3961 tgtagtaatt cagacctggc tgaatatcct tttcgtcacc tccgttggca atcgccgcag
     4021 ccaatacagc aaattgtgct tggttggcaa tcgtcacatc ccccacgcta acttgatagt
     4081 caccctcttg cagctccttc cagctagtcg gtgcttgctt cacattctct ttatcggtga
     4141 taaaggaaat ggttcccgta tagcttaaca accaatcccc atcatcatcc tttgcccaat
     4201 ccggaatttc ctcccaatag ttggtcttat aaggtaaggt taactctttg ctttcagcca
     4261 acggaccgaa gctgataccg acatcaccaa tatcggcggt tccatttttt ccttctgatt
     4321 caaacttagc caattcttct gcactggaca tatccgtatc cacgtgactt aagccgtatt
     4381 ctttttcaag gtcgttccaa gtgcctaccc aatttgccca agtatccggc attcccaagc
     4441 tggcaatctc tccttcttcc ttggcttttt ctataatcgt atctaaagag tcgtctgccg
     4501 cagccgattg cttcgttgct tcacctgagc cgcagcctgt cagcaggata cttactgttg
     4561 ctgcacaaaa taaaccgata gtcatgttac gaattttttc attcattttc attcattctt
     4621 ctcccctttc gataattcca ttctaacaaa gctttgtaat gagagaatca gtttcttgaa
     4681 aaggtttcat gaacaatgta aaggttgtat atggtttgta aatttcgacg aattcccgtt
     4741 aaccttctaa agcttttgcg gtatgatagt agaaaaaagg aggctcccta tgcagtatta
     4801 tgatcagcat ctccacacgt atttttcctt tgattcagag gaaaaatttg aaaactattt
     4861 agcctatcag ccggagtttt tcgtttctac ggatcacttt gatttaaaca atccatctac
     4921 cggaaaagat gacattccgg attatccagc ctatataaac aaactggact ctttaaaaga
     4981 aacctattcc accaaatttc tgcgaggtat cgagattggc gttgttccag gacaagaaga
     5041 gcggatcgtg gattacctcg ctcagcatcc ttatgattta aagctggtaa gtattcatca
     5101 aaatggccgc tttgattata tggacgatgt ggttttaacc aaagatccca ttcaaactac
     5161 caaggaatat tttgatcaga tgttgcaggt cttgacggat tttccagaag gagatatttt
     5221 gactcacttt gattatggat tacgccgctt caccttcaca gcggaagaat tcgcggagca
     5281 ttttgaggct cagctgctaa cgattttcaa aaaggttgtt gaacgagaat tggcgatgga
     5341 gttaaatgcc aagagcttct tgaaatacgg caacgaagac ctttaccgtt atgccgttcc
     5401 tttgtatcaa agtgtcggcg gaaagctctt taccttaggc tcggatgctc atgttgccga
     5461 agattatcag ctgggcttta aaaaaatgag tcagctgttg gcagactgtc aggtagaaaa
     5521 gttgctagtc attcaaggaa aagaacgccg cctgacgccg ctgccgattt tgtgattcct
     5581 atataataga agaaagtggt gaaaaaaatg agcaacctgt gggactacaa tcaagaggca
     5641 cccatccatt atttaattgc gcgacattgg gatgcgttga aaattgaggc ggtttgccga
     5701 tccttgttag cagccgttcc aaaacaacaa ctggaaaatt ttttggtggc tgacagcttg
     5761 cagcgggaaa aagttcaggc ttattttgca gcctttaaag atcagccttt ggaatatttg
     5821 catgcgcagt ttcatctttt ttatcaagta gccgccccag atgactacaa cgatttacga
     5881 ggacagctgc aattgacctt tcaagcggat gaaaccgcct ataccgtttt attgggaatg
     5941 gctcgccttg gtgatcaggc gaaggtcgag tggcggattt tcgatatttg atggcaggat
     6001 caaggcgttt cagttgcaaa ccttcctctc tttcaattag aaaaaccgca gcaggaagaa
     6061 gtttgtgtgc tggtcaccga tgctggtgaa attcgtctcc gcttatttcc tgaccaagct
     6121 cccctggctg tagccaactg gcgctcccta gctgagcaag gcgtttatga caacacacct
     6181 ttcggctcgt gtcattaagg aatttgttat tcaaggtggc gctttggatg gttctggtga
     6241 tgaagctgtt tccagctatg agggcttttt cgctgatgaa gtgcatcgcg gactttatca
     6301 ttttaatggc gccttggcct taggggacca cggcccccac accaacggca accagttttt
     6361 tattgtgcaa aacacaaagg cgcaggctga cctgctaatg taaagcaagc atacttggag
     6421 cttggaggac taccggagct ggatggtcgt tatactgttt ttggacaggt ataccaaggg
     6481 ttagaaatcg tagcagcgat cgcagctcag ccgacaaaca gtgaagatgt accgattgag
     6541 ccagtgttca ttcgacaaat taacttcgaa aaaacatcgt aaaaagacac tcactgactt
     6601 cagcaaaagc tctattcttg agctggctgc agctagtgag tgtctttcat ttatccataa
     6661 gataaagctt ggattcaata aataaataaa tgttttggtt aaagctgtga ccagcaaatg
     6721 aggaaccgtg cgagccagtt gatctgccaa tgcaaacatt tctttaggtg aaggcgctgg
     6781 cgtgtctgcc aacggatact ccagtcccaa tgcttggtaa ccgtgcatac catagcagtg
     6841 gtacggtagt aattctaacg gtacgaaccg atcaagatct gccacaaaac aagcaatcgt
     6901 cagcagctcg gtcaggttca tattgatacc tggaaccaca ggaactcgaa ttcgcacttc
     6961 gcagttagga tactcaatta aaaagcgacg aatattcttc aaaatttgtt ggttatctaa
     7021 gccggtccat tgtttgtgga gcttgctggt aaacattttt acatccacaa acaatgtatc
     7081 cacataggga gctacctttt ggatttcatt ataagcacca caaaagctgg tttccagtac
     7141 ggtattgatt ccaatgtatt tcgatttttg caaaatttct ttagcaaaat ccgcctgaac
     7201 cagtgcctcg cctccgctaa tggtcactcc gccatccgag tgaaagtaaa aaacagcatc
     7261 cttctcaatc tcatccatta cctcttcagc ggtcatggtc tggccaaatc ctttttcaat
     7321 ctgcttgctt tgtgattcgg gaatcgaaca ccaggcacag cgtaatgggc agccctttaa
     7381 ataaacaacg gtccgtaaac cagcaccatc atgtagagaa ccctgttcta ttcttaatac
     7441 tgttccttcc atatagattt ttgaattaca cactagttta aactaaaaca cacaaggaaa
     7501 aacttaccat ttaatcataa aattagctca tataaatata ctaggatgta aaatagactg
     7561 gtcaaaatct ggtcaaaaaa gaggactaat acaggtagtc ctcttttttg ttattttaat
     7621 attctaaatc attttttatt ggtttattcc cttattcgat gtagactcaa atcactatat
     7681 cactagatat caaacggcgt catacggaat caaaaacatc aaatttgacc tgttaaatgg
     7741 tcattgaata acattcaaaa tcaataaaac ggagtcagac acggagtcaa aaacgctgag
     7801 agtaaaaaat atatacagcc ttgtaggtaa agtaccacag ggctgtatat tttttatttc
     7861 agattacctt aaatgattcc atttactttt tatctcattt tttcctacta gttagtatca
     7921 aatactctcc tattttctca ataaactatt tttggataca tggtatctga aacagctaaa
     7981 accttgtcat tacagcaaaa aatcacgtta t
//
LOCUS       DAFBSV010000105         7930 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.108, whole genome shotgun sequence.
ACCESSION   DAFBSV010000105 DAFBSV010000000
VERSION     DAFBSV010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7930
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.108"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            143..847
                     /locus_tag="LLB18_002488"
     CDS             143..847
                     /locus_tag="LLB18_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011476586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBK5245464.1"
                     /translation="MTKHTHHEIGDHAACIRLVPIFNHLEDSAMNYIAEKAHTKQYQK
                     GEFLFRSQEKEDTLYIINRGKIRIYRLADSGKEQLVRILNPGDFTGEWTLFNPDAVHE
                     EYAEATRDTVVCMIQQKDVQDFLEQYPAISLKLLAEMSKRLESSERQTTQVAVESVIT
                     RLVLFLAENVEPEMGNSPTITLPMAKKDIASYLGTTPETISRKFGELEDEGLIQQLSG
                     KRIKIQDLDDLLLYSE"
     gene            1075..1413
                     /locus_tag="LLB18_002489"
     CDS             1075..1413
                     /locus_tag="LLB18_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245465.1"
                     /translation="MHCFWVIVAITLSAAGAFFVVPFTKNTIGGEAKTSNVVEADRLA
                     MEKEEEVVKGAGVIGHGKVAYYEASDQGDKSVFTVWFPWSLAGILFSITMTRMTRKIE
                     EMEQIEWDSY"
     gene            1398..2252
                     /locus_tag="LLB18_002490"
     CDS             1398..2252
                     /locus_tag="LLB18_002490"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBK5245466.1"
                     /translation="MGFVLGVLNPHVVEIGSVVIHWYGVIIAAGILAALQLSTKEAKK
                     KGLEEDTIIDMALWAIPIGLLGARLYYVLFELGYYLQNPGQILAIWNGGIAIYGGLIA
                     GGGTLYWYAKKKGTSLALVLDILAPNVLLAQSIGRWGNFMNQEAHGGPVTRQFLENLY
                     LPEFIIEQMNMNGTYYHPTFLYESLWSLLGFVLIVTIRNRKQLLRQGEVALSYVLWYS
                     VGRFFIEGMRTDSLWIGEWIRVSQALSLALFIGAIVVWFIRRQDYPPISYYSDGNKGQ
                     KKTIKMVN"
     gene            2399..2632
                     /locus_tag="LLB18_002491"
     CDS             2399..2632
                     /locus_tag="LLB18_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HBK5245467.1"
                     /translation="MEKAILQLETLSCPSCMQKIEGAVKSVNGIDKDSIKVLFNSSKV
                     KTNFDSAVTSIEEIQKAIENVGYPVLKAKVKAV"
     gene            2830..4734
                     /locus_tag="LLB18_002492"
     CDS             2830..4734
                     /locus_tag="LLB18_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBK5245468.1"
                     /translation="MQQYILSKKNVITVISGLLIVLGFFSHFVLENVGLSEWSLIIAS
                     VFGITPIAIQAFQAMKVKVISIDVLVSIAAIGALFIQNYEESAIVTFLFLFGHYLEQR
                     TLNQTRSAIKELTEMAPESALKQMDNGEFEEVEVDDIDEGDILLVKTGAKVPVDGIVL
                     TGEGHINEASITGEAIPVNKLADAEVFAGTILENGTIQIRADRVGEDTTFGKIIELVE
                     EAQDSKSEAERFIDRFSKYYTPAVLVLAIVVWAFSQNIELAITILVLGCPGALVIGVP
                     VSNVAGIGNGARNGVLLKGSEVIQDFSNVDTIVFDKTGTLTVGNPTVAATELYEKDPA
                     ETLGYLASVERESDHPLAKAVLNQIGETNFYPVEGTEVVKGGGIVSSVAGHRVAVGNV
                     ALMEKENVTLSKKVQKDVKRFEQQGNSLVLTAVDGELKVLMGIRDQVRPGVKANLQEL
                     KDLGVKNLVVLSGDNQGTVDVVAGELGLTEAHGYMLPEDKSAYIGKLQQRGQIVAFVG
                     DGVNDSPSLALADIGIAMGSGTDVAIETSDVVLMNSNFSNLPHALGLVKATANNMKQN
                     IVISVGVVLVLLTSVFFSEWMNMSIGMLVHEGSILVVIFNGMRLMKYKLKGRKEQKEV
                     SAPTEKVKIS"
     gene            5088..5453
                     /locus_tag="LLB18_002493"
     CDS             5088..5453
                     /locus_tag="LLB18_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5245469.1"
                     /translation="MTAEVCTTTCIHKEKVASVKNNLKDKDLSTLLVLGKCFSDSSRI
                     KIFYALETYKEMCVCDLAAILNASIATTSHHLRFLKKNGMAKSRQYGKVVYYSLANEE
                     ILSAVQAFLKLSENSSMKA"
     gene            5470..6081
                     /locus_tag="LLB18_002494"
     CDS             5470..6081
                     /locus_tag="LLB18_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HBK5245470.1"
                     /translation="MLQNILSALAVYISTSIDYLFILLIIFSQNHTKKGLRQIFFGQY
                     LGTGILVAISLFAAYVLNFIPQDWIIGLLGLIPIYLGIRVAFVGEEEEEEGEVVEKLG
                     SRGTNRLFWTVSLITIASGGDNLGIYIPFFTSLSFSEIVTSLIVFAISVAVLCYISYK
                     FAKISFVSETLEKYERIIVPIVFIGLGIFIMIENGTIQTILGL"
     gene            6109..7770
                     /locus_tag="LLB18_002495"
     CDS             6109..7770
                     /locus_tag="LLB18_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBK5245471.1"
                     /translation="MSENKKYHEWILEGIDCANCADKVERGVAKVAGVANSSVNYMTE
                     TLSFEVTEEKEYLVLSNVQQKVKKLEPDITLKNKVDGRLIEINPALIKKSNLKDDKKN
                     YEWILEGIDCANCAAKVERGVATVPGVTNSSVNFMTETLSFEVAGENKTDVLASVKQT
                     VGTLEPDVVLRKKSDGTLIEHGTDSNKNSTSNKSISDKDETNQKQTNRAYLASLLGNK
                     TKITLIRLILGLGILATGIFLPMDGQASLGLFILAYLITGYDVVGRAIRNIFRGQVFD
                     ENFLMTIATLSAFYIQEYPEAVAVMLFYQVGEVFQDIAISKSRRSIADLMDIRPDYAN
                     LVTGNNVEKVAPEAIKIGNIILIRPGEKVPLDGKVVEGASAMDTSALTGESVPRSVKP
                     EDTILSGFINKNGLLKVVVEKPFSESTVKKILDLVQNASGRKAPTEQFITKFSRYYTP
                     IVVIAAALLAIVPPLLVPGATFNEWIYRASIFLVISCPCALVVSIPVGFFGGIGSASR
                     KGILVKESNFLEGLNDLKYVVMDKTGTLTKGFCCKVLNLLSNKVE"
     gene            7798..>7930
                     /locus_tag="LLB18_002496"
     CDS             7798..>7930
                     /locus_tag="LLB18_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBK5245472.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     "
BASE COUNT         2506 a         1294 c         1766 g         2364 t
ORIGIN      
        1 taaaagtaga agctgattta gggattggaa ttctttccag tcctttttcc attttcttga
       61 tgtgcatcaa tttttttgta gtaagagact tatataataa aagcagcgaa tataaacaaa
      121 ataaataaag ggggagaatg aattgactaa acatacccat catgaaattg gcgaccacgc
      181 agcctgtatc cgcttggttc caatattcaa tcacttagag gatagcgcga tgaattacat
      241 tgctgaaaaa gcccacacga aacagtatca aaaaggagag tttctgtttc gttcacaaga
      301 aaaagaggat actttatata ttatcaatcg tgggaaaatc cgtatttatc gattggcaga
      361 ctctggcaaa gagcagctag tgcggatctt gaaccctggt gatttcaccg gagaatggac
      421 cttgttcaac ccggatgcag tacacgagga atatgccgaa gcaacccgag ataccgttgt
      481 ctgtatgatt cagcaaaaag atgtccaaga ttttctggaa caatacccag ctatttcttt
      541 aaaactattg gcggaaatgt ctaaacggtt agaaagttca gaacgtcaaa cgacacaagt
      601 agccgtggag agtgtcatta cccgtttagt tttgtttttg gcagaaaatg tggaacctga
      661 aatgggcaac tctcccacca tcaccctgcc gatggcaaaa aaggacattg cttcctattt
      721 aggaacgaca cctgagacca tcagtcgcaa atttggagaa ttggaggacg aaggattgat
      781 tcaacagctg tctgggaaaa ggatcaagat tcaggattta gatgatttat tgctttacag
      841 cgaataatcg gacacacttt tttctacacg ttggtgttct gtcgctcttc attaacaacg
      901 ggacagaact cagtgctttt gcttccatct gtccgttttt ggctttttta agacagaacg
      961 accttcattc attggaaaaa taaaagcaca aacatgataa ccctcaagtt tttttgtttt
     1021 atttttcttt aagatagggt tgtcgaacaa aacgtaaaaa taagtagggt gaatgtgcat
     1081 tgtttttggg tgatagttgc catcacgttg tcagcagcgg gggcattctt tgtcgtccct
     1141 ttcaccaaga acacgattgg cggcgaagca aaaacgtcta acgttgttga ggcagatagg
     1201 ttagctatgg aaaaagaaga ggaagttgta aaaggagccg gcgtaatcgg acacggaaaa
     1261 gtggcgtatt acgaagcgag tgaccaggga gataaaagtg tattcactgt ttggtttcca
     1321 tggagcttag ccggaatctt gttcagcatc accatgacta gaatgacgcg aaaaattgaa
     1381 gaaatggagc aaatagaatg ggattcgtat taggcgtttt gaatccccat gtggtggaga
     1441 ttggttctgt tgtgattcat tggtatggag tcattattgc agcgggcata ttagcggctc
     1501 tccagttgag caccaaggaa gcaaagaaaa aaggactgga agaggatacc attatcgata
     1561 tggccttatg ggcaattccg attggactcc tcggcgctcg gctttattat gtgttatttg
     1621 aacttggtta ttatctgcaa aatccaggac aaatccttgc gatttggaat ggcggcattg
     1681 cgatttatgg gggattgatt gcaggagggg gtacgctata ttggtatgca aagaaaaaag
     1741 gtacttcttt ggcactcgtt cttgatattt tagcgcccaa tgtattgtta gcccagtcca
     1801 ttggtcgttg gggcaatttt atgaatcagg aagctcatgg tgggccggtt actcgtcaat
     1861 tcttggaaaa tctttattta cctgaattta tcattgaaca aatgaatatg aatggtacct
     1921 actaccatcc gactttttta tacgagtcat tgtggagttt gttgggcttt gtcctcatcg
     1981 tcactatacg gaaccgaaaa cagcttttgc gtcaaggaga agtcgctttg agttacgttt
     2041 tgtggtactc agtgggtcgg ttcttcattg aaggtatgcg aacggacagt ttatggattg
     2101 gcgagtggat ccgcgtttcg caagccttgt ctctggccct gtttattggc gcgattgtag
     2161 tatggtttat acgcagacaa gattatccac caatttctta ttattctgat ggcaataagg
     2221 ggcagaaaaa gactattaag atggtgaatt gagcaaaaag ataaaaagaa gtgcaaaact
     2281 tgatatgcgt caattttcgt ttgctaaaag tgagctatac tacagttgta aagaggaaaa
     2341 ggcagtgttc attaatctgc tgccgataaa ataaaaacac ataaaggaga taggaattat
     2401 ggaaaaagct atattgcaat tagaaacgtt gtcttgtcca agttgtatgc aaaaaattga
     2461 aggtgccgtg aaatcagtta acggtattga taaagacagc attaaagtat tattcaactc
     2521 cagcaaagtc aaaaccaatt ttgattcagc tgtcacttcg attgaagaga ttcaaaaagc
     2581 tatcgaaaac gtaggctatc cggttcttaa agcaaaagtc aaggccgttt aacagattaa
     2641 atgaactagg caattctgga agaaaagcta tttttccagg attgcttttt ttgttgcaat
     2701 ccgattcgag gtgcttagaa acgataaaag agaactttct aaacttgatg tcagtcaatt
     2761 aattacttag gcaattatct tatactgtgt ttatcaataa aagagaaatt aaatttggag
     2821 ggaaaaagca tgcaacaata tatattaagc aagaaaaatg ttatcaccgt catcagtgga
     2881 ttgttaatcg tactcggttt cttcagtcac tttgttttag aaaacgtagg actttcagag
     2941 tggtctttga tcatcgcctc tgtctttggg attacgccaa ttgccattca agcgtttcaa
     3001 gcaatgaaag tcaaagtcat cagtattgat gtcttagtca gtattgcagc gattggtgcg
     3061 ctttttattc aaaattatga agaatcggct attgtcacgt tcttattctt attcggacac
     3121 tacttggaac aacgaacatt gaaccaaacg cgatctgcta tcaaagaatt gactgaaatg
     3181 gcacccgaaa gcgccttgaa acaaatggat aatggcgaat ttgaagaagt agaagtggat
     3241 gatatagatg aaggggatat cttgctcgtt aaaacgggtg cgaaagttcc agtagatggc
     3301 atagtcctta cgggtgaagg gcatatcaat gaagctagca ttacaggtga agctattccg
     3361 gtcaacaagc tagctgatgc agaagttttt gcaggaacca ttttagaaaa cggaacgatt
     3421 caaatcagag ctgaccgagt tggtgaggac accacatttg gaaaaattat tgaactcgtg
     3481 gaagaagcac aagattctaa atccgaagcg gaacggttca ttgatcgctt ttctaaatac
     3541 tacacaccag ctgtcttggt tctggcaatt gttgtatggg cgttcagtca aaatattgag
     3601 ttagcaatca ccatcttggt tctaggttgc ccaggcgcat tagttatcgg agtgcctgtc
     3661 tcaaacgttg ccggtattgg gaatggtgct cgtaacggtg ttcttttaaa agggagtgaa
     3721 gtcattcaag acttcagtaa tgtggataca attgtatttg ataagacagg tactttaact
     3781 gtcggaaacc caaccgttgc agcgactgaa ctgtatgaaa aagatcctgc tgaaacgctt
     3841 ggctatctgg ccagtgtgga acgggaatca gatcatccat tagcaaaagc ggtcttaaat
     3901 caaattggag aaacaaactt ttatcctgtt gaaggaactg aagttgtgaa aggcggcgga
     3961 atcgtttcaa gtgtagctgg acatagagtg gctgttggga atgtggcctt gatggaaaaa
     4021 gaaaatgtca ctctcagcaa aaaagtgcaa aaagatgtca aacggtttga acaacaaggg
     4081 aactctctcg ttttgacagc ggtcgacggt gaattaaaag tactgatggg cattcgcgat
     4141 caagtccgtc cgggtgtgaa agctaatttg caggaattaa aagacttggg cgtgaaaaat
     4201 ctagtcgttc tttcaggaga taaccaagga accgttgatg tggtcgccgg cgaacttggt
     4261 ttgaccgaag ctcacggcta catgttgccg gaagacaaat cggcttatat cggaaaactt
     4321 caacaacgtg gtcaaattgt agcctttgtt ggagatggcg ttaacgatag tccgtcctta
     4381 gctttagcag acattggaat cgcaatggga agcggaacgg acgtagcgat tgaaacatcc
     4441 gatgtcgttt taatgaactc gaacttcagc aacttgcctc acgcattagg attagtaaaa
     4501 gccaccgcaa ataatatgaa acaaaatatc gtgatttcag ttggagtagt gttggtcttg
     4561 ttgaccagcg tcttcttcag cgaatggatg aatatgtcta tcggaatgtt ggttcatgaa
     4621 ggtagtatct tggtggtaat tttcaatggc atgagattaa tgaagtataa gttgaaaggt
     4681 cggaaagaac aaaaagaagt atcagcacct acagagaaag taaaaatatc ttaagaataa
     4741 attagaagag gctgagacaa tagtccatcc ttgaaatgac aaaagcggaa actcagattt
     4801 ttaaatctgg gattttccgc ttttttgagt tcttgaaaaa aaataagagt atagagtatg
     4861 ttctttataa aattaatttt cgtgtaaatt attaaaaatt taataataaa atttaaattc
     4921 ctattaagtt gtaacacatg aaattgctta aaatagtgta tcaaaaacct tgttttatta
     4981 atgttgaatt tatttgaaag gtctacagat taacatatta ttgacaaaac aatatttaaa
     5041 tagttatact tcattcaaac gtctgtttga acgaggtggt gaagttaatg actgcagaag
     5101 tatgtacaac tacttgtata cataaagaaa aagtagctag tgttaaaaat aatttaaaag
     5161 ataaagacct ttcaacttta cttgtattag gaaaatgttt tagcgattct tctaggatta
     5221 aaattttcta tgctttagaa acgtataagg agatgtgcgt ttgtgattta gcagcgatac
     5281 ttaatgctag tattgctaca acgtcacacc atttacgttt tttgaaaaag aacggaatgg
     5341 cgaaatcacg tcaatatgga aaggtagttt attactcttt agcgaatgaa gagattcttt
     5401 ccgctgtgca ggcttttcta aagttgtcag aaaatagttc tatgaaagct tagtttggag
     5461 gtagttattt tgttacaaaa cattttatca gcactcgctg tatatatttc taccagtatt
     5521 gattatttat ttatcttgct gattattttt tctcaaaacc atactaaaaa aggtctccgt
     5581 cagatttttt ttggtcaata tcttggaaca ggaatcttgg tagccataag tttgtttgca
     5641 gcatatgtgc taaattttat tcctcaagat tggatcattg gtcttctggg actaattccg
     5701 atttatttag ggattcgtgt tgcttttgtg ggcgaagagg aggaagaaga aggggaagtc
     5761 gttgagaagc taggatctag aggaacgaat cgtttgtttt ggacagtttc cttaataacg
     5821 attgcttctg gtggcgataa tttagggatt tatattcctt tctttacctc gttatctttt
     5881 tcagaaattg tcacttcttt aatcgtcttt gctatctctg ttgcggttct ttgctatatt
     5941 agttataaat ttgcgaaaat ttcttttgtc tctgaaacac tagaaaaata tgaacgaatc
     6001 attgtaccta tcgtatttat tggattaggg atttttatta tgatagaaaa tggaaccatc
     6061 caaactatat taggtttgta gagatcttat tagtaaagga agcaaacgat gagtgaaaat
     6121 aaaaagtacc atgaatggat attagaagga atcgactgtg caaattgtgc agacaaagta
     6181 gaaagaggcg tcgccaaagt tgcaggtgtt gccaatagta gtgtgaacta tatgacagaa
     6241 accttgagtt tcgaagtgac agaggaaaaa gaatatcttg ttttatccaa tgtgcaacaa
     6301 aaagtaaaaa aattggagcc tgatatcact ttaaaaaata aagtggacgg taggctgatt
     6361 gaaataaatc cggcattaat caagaaaagt aatttaaaag acgataaaaa aaactacgaa
     6421 tggatattag aaggaatcga ttgtgcaaac tgtgctgcca aagtggaaag aggagttgct
     6481 acagttcccg gcgttacaaa cagcagcgtc aattttatga cagagacact gagcttcgag
     6541 gtagcaggtg aaaataaaac tgacgtgttg gctagtgtaa aacaaacagt aggaacttta
     6601 gaacctgacg ttgttctgcg aaaaaaatcg gacggtacat tgattgaaca tggaactgac
     6661 tctaataaaa attcgacttc taacaaatcg atttctgata aagatgagac aaaccaaaag
     6721 cagacgaata gagcttatct ggccagcctt ctcggaaata aaactaaaat tacccttatt
     6781 cgtttaatac taggattagg aatattagcg acaggaatat ttctccctat ggatggacaa
     6841 gcctctcttg ggttgttcat tctggcttat ttaatcaccg gttatgacgt tgtaggacgt
     6901 gccattagaa atattttccg aggtcaagta ttcgacgaga actttctaat gaccattgcg
     6961 acgttaagtg ccttctatat tcaagagtat cccgaagctg tagcagtcat gctattttat
     7021 caagtgggag aagtattcca agatattgct atttcaaaat ctcggcgctc cattgcggac
     7081 ctaatggata ttcgacctga ttatgccaat ttagtcacag gaaacaacgt agaaaaagtt
     7141 gctcctgaag caattaagat tggaaatatt attctcattc gtccgggcga aaaagtgcca
     7201 ttggatggaa aagtagtgga aggtgcttct gcgatggaca cttctgcttt aacaggcgaa
     7261 tccgttccaa gaagcgtgaa gccggaagac actattttga gcggatttat taataaaaac
     7321 ggattgctaa aagtagttgt agaaaagccc ttttcggagt ctactgtgaa gaaaatttta
     7381 gatttggtcc aaaatgctag tggccggaaa gcacctactg aacaattcat taccaaattt
     7441 tctcgctact atactccaat tgtggttata gctgctgcct tactggcaat tgttccgcca
     7501 ttgctagtac caggcgctac ttttaatgaa tggatatata gggccagtat ctttttagtt
     7561 atttcatgcc cttgtgcttt agtcgtttcg attccagttg gtttctttgg tgggattggt
     7621 tctgcttccc gcaaggggat tttagtaaaa gaaagcaatt tcctcgaggg tttgaacgat
     7681 cttaaatacg tggtaatgga caaaacgggt acattgacaa aagggttctg ttgcaaagtt
     7741 ttaaatctac tatcaaataa ggtagaataa tagaaaaaga tagtaggagg aatgacgatg
     7801 aatcatttta aaggaaagca atttcagcag gatgtgatta ttgtagccgt gggatactat
     7861 cttcgttata accttagcta tcgtgaagtt caagaaatct tatatgatcg tggcattaac
     7921 gtttctcata
//
LOCUS       DAFBSV010000106         7625 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.109, whole genome shotgun sequence.
ACCESSION   DAFBSV010000106 DAFBSV010000000
VERSION     DAFBSV010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.109"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(14..706)
                     /locus_tag="LLB18_002497"
     CDS             complement(14..706)
                     /locus_tag="LLB18_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBK5245473.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEIGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            complement(1143..1712)
                     /locus_tag="LLB18_002498"
     CDS             complement(1143..1712)
                     /locus_tag="LLB18_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBK5245474.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1786..2109)
                     /locus_tag="LLB18_002499"
     CDS             complement(1786..2109)
                     /locus_tag="LLB18_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245475.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2263..3075)
                     /locus_tag="LLB18_002500"
     CDS             complement(2263..3075)
                     /locus_tag="LLB18_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245476.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3429..4277
                     /locus_tag="LLB18_002501"
     CDS             3429..4277
                     /locus_tag="LLB18_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBK5245477.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4422..5363
                     /locus_tag="LLB18_002502"
     CDS             4422..5363
                     /locus_tag="LLB18_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HBK5245478.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5353..7524
                     /locus_tag="LLB18_002503"
                     /pseudo
     CDS             5353..7524
                     /locus_tag="LLB18_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2272 a         1512 c         1371 g         2470 t
ORIGIN      
        1 agggggggat tttttatcgt tgtggaatat ttaaatacca acgcttgtca tgaaaatctt
       61 gtgctccacc cttagtattt ccttctggat cgtttgtcgc acgcatcatg acgtatactt
      121 tcttattagg gaaatcacgc atattgaaag atacatgata gccaacattt cctaaagtat
      181 tataagcttg atttacgtct ggtctataaa tcccatcagc tcttactcta gctagttctt
      241 ttccagtatt gtagtccata atgaaaatat actcgtattt ataattagca atgtgccatc
      301 cagctacatg caagtttgcg ttttcgattt ctccgaactg atcaatgtgg gcgtaatttg
      361 ttccatctgt cagcgtagaa tttgcagcac ctgctcgagt tggatcaatt actggtttat
      421 cctccgaagt agttggatta tcatccgtaa aaccatgagc caaatcatag gctagttttt
      481 ctttacttac acctatttca gaaagataac cgtaaggatc tgtatgatcg ccccaaatat
      541 tttgtgttac ccataaatgc gatttgattc ctggttggtt ataaggagtg tctaatgtta
      601 atggaatacc atatttcatt gctgaatctc ttgccaattc aacgtatact ttatagttct
      661 tttcaaaagt ttctttatca tgtgtgtgtt gtaactcgat ttgcacagga cttttggctc
      721 acgaggttgt cctactctac atcttgctga tagatatgct gaaaggaaaa caccaacatt
      781 atgttttgct ttttcagcta gaacgagaca agcaggaata cctttagaag atatcaaagg
      841 ttttttaggt cataaagatg tttccactac acaagtctat gcccatattt ctcccgaagt
      901 gaaaaaaaga tcaatgaatc aactagaaaa ctatatagaa gagcaaataa aaaagcactc
      961 aaattgagtg cttttttaag ctcactatca ctaaaactat cactaatttt atttataagc
     1021 gaacatgttt ctatcactga ttttttaaat ctagcgaaaa acccttatct taaaggcgtt
     1081 cgttcaattc tttggcaagg tcttcaaagc ctggcttgcc tagaagtgcg aacatggttt
     1141 tcttatagct catgtagaaa aattttcttg atgatgattt tatccatcaa ttgagattga
     1201 ctgttttgct ctcctatgat ttcagctatg attgtccgat tttgcggttt tcttcttaac
     1261 tggtagttga ttttcccagt ttccatcaac tcgctaagca tatccacgac tccgccaaat
     1321 ccggtctttt tcgtaataaa acctagtgct accattcgtt catctagatt ttttgctgta
     1381 atcgtcacac cagtaatgag cgagtgctgt aatgtttggg ccagctcttc catcccttca
     1441 gcattggata cgacggaagc tgttttgtta ataggttctt cgtttatttc ttttggttct
     1501 ttcctctcca ctttcactgt ttgacgaagg acatctagtt cttgcaagag cgtttcgtat
     1561 tgttcttggg tcagcatcac gccagctact ttttcacgat taaatatata tacgccagtt
     1621 cccgcgtctc gcgcttgagc aaatacatcc atcggcgatc gtttcacttc tgtgatcgaa
     1681 gatgtgggaa cttctaattt ctttaattcc aatggatttc ctcctttact aatcgctttt
     1741 tattatagca cagactgact tgttttgatc ttttttccaa aggttttatc ggtttttgcc
     1801 taaccagtaa ttgatatcgg taagaagtct ttcgatacca aatgaaggat ggtacagata
     1861 cgttttttga tcttcgttat ggtctagtgg aaaaaaatga tcgatgatca ctagatctgc
     1921 ataccgaggc ggcttatttc gagtacatac atgtatagag atccgttttc gatgtcttag
     1981 cgttttgttc agtaccccag caagtcttct tgcttcttgg tgttcatagc gaaaaaaaaa
     2041 gacgattttc acttcaggag ggtggacatc taaataccct cgttcctgga gtgttttcag
     2101 taaaagcatc ccccactcta ctgcggggtg tgcaagtgct tgttggatcg ctagccgaaa
     2161 ttgatatagt ttatctttgg aattgggaaa tttttctaat gtttcctgat aataacgaac
     2221 ttcttctatc agccggtcat ggataccaat tacgtaacga agtcattctt ggtaaagtac
     2281 ttttgtcagc tttgatttgc tttcgctctc aaattcgcta ttcagccaaa acagcgaatc
     2341 aagcttttca gtcacaatcg tcaatttccg atagtcttgt gtctcttcta tccgtttcca
     2401 ccgcttttca gtaatctggt tacagctcaa gcgcaaaatt gctagataat ttttttcttt
     2461 tattggcaaa atctgctcct ctctaaatag caattcagga aacaattcaa agaatagtgt
     2521 tcgactgtct cctaaaatct cgatttctgc cggatccttt ctttgcttca ataattggat
     2581 gaacatctca gaaaaggact gctctccatc atctgcaaaa aaatgcggaa aatctttcaa
     2641 aaagcaaaac agcagatatc ttacttttct ttctgaacca aagatctgtg cttttttata
     2701 agaaaaagaa aggtggtact cgccaaacca ctttctcaat cgctcttgcg tagaacgatc
     2761 gtacttctgc tcgtaaggtt cattcaatag cagatttttc agtaaacaaa acgggggtga
     2821 ttggatcaga aaaacaaaca agagataagg ttcgctatat ccttgatcat aaactaactg
     2881 aacggttttc ttatgaagaa tcagctgaat gggacagtcg ctttccgcca aacgtttcag
     2941 atgccgatcc actgttttaa catcgatttt cagttcttca gctaaatcag cttttcgcca
     3001 gatcaaatct ttcattagat tgattagtga aaataaattc tgtgcatttt ttgataatag
     3061 tttttgccat ctcatcgatc atttctcacc tgatttctaa acatattgtt tgatcaaaat
     3121 gggttcactc ctaaaaagat aaaaaactcc ctttctattt atttaaatac gcaaatcttc
     3181 ctcattattt tttattttac tcaatttaat cgtattctca tttcaaaacg aatgtacttt
     3241 aaaaaaacat aataagatca ctttgcttgt aggatgtatt cccttccatt acaatgaaat
     3301 aaatagcgat tttatgagaa ggtgatgtga aaatggaaga aaaaatagaa gaatccaaac
     3361 aaaaaatcga tcagttgata taagaattag aaaaagcggt catcggcaaa cgttcaacta
     3421 tccaattgat gatcgtggcc ctattagcag gtggtcatgt cttattcgaa gatattcccg
     3481 gtgtaggtaa aacgttactg gtcaaagcac tagcaaaagc tgtacaggga accttcagca
     3541 gagtccaatg tactcctgat ctgctgccta gtgatattct tggtttttcc gtatacaatt
     3601 cacaatcaaa agagtttgaa tttcgtccgg gaccgatctt taccacgatc ttgttagcag
     3661 atgagatcaa tcgtacgact cctcgtactc agtcagcact tttagaagca atggccgaga
     3721 atcatgcaac gatcgacaac aatacatacc ctctagacaa tcattttttt gtcttagcta
     3781 cgcaaaatcc aatcgagtac gaaggaacat atcctttgcc ggaagcacag ctcgatcgtt
     3841 ttttattccg actacaaatc ggttatcctt cttttgatga cgaacttttg ctacttttgg
     3901 ataaattcga aaaagtgttg gataacttaa atgaagtatt gaacagttat gaaatagaag
     3961 aaataaaaac aaatgtggcg aatgtctttg tcagtcccga agtggcatct tatgccttgc
     4021 agttagtgtc agcaacaaga agtcatgctg ccatccagct tggcatcagt ccacgaggaa
     4081 gcctttcctt tattcaggca gcaaaagctt atgctttaat ccatgggaga aattacgtca
     4141 cgcccaaaga tttgcaggat ttagttcctt acgtgttttc ccatcgcctg attttttacg
     4201 atcgttcatt gaaggaagac gaaaagaaac aaatcattca tactcttgtt gcacaaattc
     4261 ctattcctgt gaggtagatt gaggtagaca atggaaaaaa tcaaagatta tttcattaat
     4321 tttgtgttat ttctggtata tttcatcatt gtgctttttg ctcttgtatt caacaattct
     4381 ttaggctggt tcttgttggc cttttttact ctttatgtat catggagctt gatttcatta
     4441 agcagctttc taaagaaact ttcggttact tgtacattgc agccactcgt ttatcgcaaa
     4501 aaaagtatgc aggttatttt ttccatagca aaaaagagaa ctttttcttt acctctccct
     4561 cgtttacaaa tcggcttccc agcaatcttt gcagaaaaaa acaagagatt ttgattctta
     4621 caaataaacc gcaagaagtc caattgcttt ggcagccaaa agaaagagga tgccatgaaa
     4681 cattaactgt catttttaca gcctatgata gtctaggact tttcagaaaa agtgcaaaaa
     4741 gagagatctc ttttcctgtg actgttctgc ctgctttttg taagattcaa gcagaaaaat
     4801 tacagagagt tctggaaaaa aaacagcagc tgaacgcgta ccaaagaggt cttgattttc
     4861 gggaacatcg cgcttatcgt ccaggtgatt ctttcaaccg aatcgattgg aaattgtctg
     4921 ctcatactca agagtggtta taccgtgaat acgattatca agaagaagaa tgttctcctc
     4981 ttttttgctt ttggggttcg cccagtccaa aatttgaacc tctgctagac ttgtattttt
     5041 ctttatggca tttgagaaaa gaaaagcagc cggaacttct gatattaggc aaccgcgcct
     5101 ttcatggcaa agaccccggt catacctatt ttgcttcttt ggaagctggc gatgagaaaa
     5161 cttttttcgc acacttgaaa aaatatgcaa aaaaacaaat cgtcctcttt gttcctgaga
     5221 attctcctga agtctcagaa gctattgaaa cattgtcaaa agatcgaacg gtttatcttg
     5281 tttatttcgt agaaaaacaa ctcatggtcc aagaaaaaga caagatatgt tcattgccag
     5341 gaggtgaatg gattgacgat taaacgggaa aaatggctgc gtggcgttta ctcctttgtg
     5401 atactaagtg taggtgctcc gatatttgta gtagctaatc aattgcaaaa cagctacctt
     5461 cttatcctaa ctattggtgt cctatgcctt attgtctgct gtattcctaa aaaatgggta
     5521 cgtttgctgc tttctttgcc agtaatgata ggttgtttgt ttttatattt tccttcgaag
     5581 acattttcca tattatggat cttacagttt ttttcgtcag ttacagagga attcttccat
     5641 ctatcccaag gtaaacttta ttatttgcca gaaaagacag ctttttttct cataatgttg
     5701 ctgatctatt tatttattac attgaccgtg gattacgact attggtacgc accctttctt
     5761 tctttgatgg cttacttcat gatgcttacc gtttttcgga aaaaagattt actgtacgaa
     5821 atgattgcgg tagtaactgt tttgttcgtg tatctggcag caaggcaatt tttctccatc
     5881 cggttgttgt cgagaaacac tcgattccag tcattgacta cagttctgct tatttgtttc
     5941 ttaactttta gcgctatctt gcctttatat cttccgaaag tacaccaatc tctcgaggaa
     6001 acgagtgaac cgatccgaga atatcttaat gatgaagggc tttatgacac actccatgag
     6061 tatcaattaa ccggaagtgc aagaacaggc ttcagtgaga atgatgaaca gcttggtgga
     6121 cctttatatg ataatggcga agttgttttt acagcgaacc aaaaaggaaa tggctattgg
     6181 aagatcgaaa ataaaaatca ttacaccggt tctggatgaa tagaagatca ggacgcaccc
     6241 atccaaccaa tccaagaatt ccctgttgac atcacgagct accaaaccgt tatagaagac
     6301 aaagaaaaca ttacattgac cctaaaaaaa caagctttct taccttatcc ttatggaaat
     6361 actaccttga ctgatttttc attagctagt ggacaaacgc tttactattt gcctgaaagc
     6421 cagcgattca ttcctgtccc gaatgaatcg acacgttctg caactttaca aacagaaagg
     6481 ttagttttta cgagagaaga attaaaaagc agtcagttaa aagctgatga tttagaaaat
     6541 cagcagacaa atcttcaatt gccaaaaagt ttgcctaaac gtattgagga cttggcggtc
     6601 gaattgacca aaaatgaagc aactttaatt cgtaaagtcg aagctgtcta acagtattta
     6661 aaaacaagcg gaaatttccg ctattccaaa acggataccg ggcatactcc aaaagaacac
     6721 gattatgtgg attatttcct ctttgattca aaagtcggct attgtgacaa cttttcaact
     6781 tctatggtcg tccttcttcg aacacttggt atcccagctc gctggacaaa aggttttaca
     6841 aatgggctca gaacaggcac agataatcaa gggaatgagg aatacagcat tctcaatagt
     6901 catgctcatt cttggccaga ggtatacttt cctggatttg gctggcttcc atttgaacca
     6961 accccttcat ttgccaatcc aatgggttca caaccagttg ctgaaacaac cgaaaccgtc
     7021 cagcctgcta tcgaacaacc aaatgaaagc gaaaatatgg cagaaactat ttccagtgag
     7081 agatctgagg tcattccatc agaagaaaca acactcacac cagcttataa aatcgtctta
     7141 ttcagccttg gagtgtgttt atccgtcttg ttgttctttc tattgttatt cagaaaatct
     7201 ctgcgctgga caagttatct tatctatctt catttttttg cttctactaa tacgattgca
     7261 tatcaaaaac ttcttaaccc tttggaaaca ttggtaccgc gcaaacccgc agaatctttg
     7321 caggaatata gcctgcgaat agaacaagaa ttcaagctag atctgcgttt cattcgatta
     7381 actactcaat atgaagcaga aatatatgga cgacaagcag atccggtaaa attcgataaa
     7441 aaaacctatt tagaaataac gcatataata agaaaaacgg tatacaaaaa aattctgaca
     7501 aaagggagcc gcttcaaaaa ataagataaa atttctggag aatctacttc tcgaatgccg
     7561 agaaccagct gattgagtat cgattactcg aaaaaaaggt tgtgacacgt tttttgtcac
     7621 aacct
//
LOCUS       DAFBSV010000107         7596 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.110, whole genome shotgun sequence.
ACCESSION   DAFBSV010000107 DAFBSV010000000
VERSION     DAFBSV010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7596
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.110"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(940..1353)
                     /locus_tag="LLB18_002504"
     CDS             complement(940..1353)
                     /locus_tag="LLB18_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HBK5245479.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1809..2294)
                     /locus_tag="LLB18_002505"
     CDS             complement(1809..2294)
                     /locus_tag="LLB18_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245480.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2433..2678)
                     /locus_tag="LLB18_002506"
     CDS             complement(2433..2678)
                     /locus_tag="LLB18_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBK5245481.1"
                     /translation="MFYHLRKENSNENLDAIALTLLIVGGLNWLLVGLFELDLVAMIA
                     GGSTTIFAKIIYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2871..3671
                     /locus_tag="LLB18_002507"
     CDS             2871..3671
                     /locus_tag="LLB18_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBK5245482.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3690..5558
                     /locus_tag="LLB18_002508"
     CDS             3690..5558
                     /locus_tag="LLB18_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBK5245483.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5551..6042
                     /locus_tag="LLB18_002509"
     CDS             5551..6042
                     /locus_tag="LLB18_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HBK5245484.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6030..6584
                     /gene="srlA"
                     /locus_tag="LLB18_002510"
     CDS             6030..6584
                     /gene="srlA"
                     /locus_tag="LLB18_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBK5245485.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6602..>7596
                     /locus_tag="LLB18_002511"
     CDS             6602..>7596
                     /locus_tag="LLB18_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBK5245486.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVPTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2706 a         1214 c         1443 g         2233 t
ORIGIN      
        1 gttactatga ataacataat aagaaagtaa agtggattga tttgagatct ttttatactt
       61 caaaaaagat aacacccaac tttcaaaaat atgttttgga agttgggaca aacgagttaa
      121 tacattttaa tacattattt tttattcaaa aaaaatagca caatggcaaa gatcgtaaga
      181 gagatcataa gccccaatga atgactaaaa agaaaagcag aatcacatgc catatcatcc
      241 catatttctt caagaaaata aataagcggg aaaaagggaa ggaatagtag aacatcgatc
      301 cagcaccatt tttttcttct tttgaaataa cataaaacaa taaacatgaa cgtgcaggga
      361 agtaaaaaca aagctttact cataactaac aaaataccag ctccttttat ttttttctcc
      421 cccacattca aagagtaaca atggtatgta cttaataata gaaaaatgga tcaacttgta
      481 tgaataacag ctgaaaagat ctgcaccaaa taaaaaactt ccagccaaaa ctgactggaa
      541 gtttattttt ttctgaaata ttctaacaca aatatgaaaa agatggccga agctaataag
      601 ccgatttcgt agcaaaacaa tgagatacca gagtcgtaat aataaaatcc tctaatctta
      661 tggataaaat agatcatcgg acaagcagat aagagtaagt atttgttagg ccttttgaat
      721 aagtaaaaga aagcactggt cattatgata aatggtatcc aaaacaaaag tttacttaag
      781 acaatcaaat gatcaactcc catatttttt accaagagag atcataacat ctttatcgta
      841 aaaacaaaat atttttttgc tcattttgaa aatttaaaca tactcgttct tatccaaata
      901 tataaaaatc gcccctcatt catcgagagg cgataagttc taatttaact caattttttt
      961 tgtttctttt ggctgataag ctgttttagg taataccaat ttcagcacac cgtttttaaa
     1021 ggttccagtg attttttctt catcaacatt aggaagatag aatgaacgtt tgtaagagac
     1081 cgaatgtctt tctttccgta catagttgcc atcttcttta tcttctgtat gggactcatg
     1141 attggcggag atcgtcaaag tattatctga atattcaact gtcgtgtctt ctttgtcaca
     1201 gccaggcata tcagcagtta gtttgtattc tttttcattt tcgactaaat ctacttttgg
     1261 ataacttgaa acacctaaaa aatcattgaa tgctggacta aacacgtcat tgaaatcagg
     1321 gaacatgtcg cgaatgctag gtacatttgc catttttgat catcctttca ataagtattt
     1381 tttatttatc cctatttacg taataactct attttgaaaa aaatgcaagt ataatggtta
     1441 gctttgtgaa tatttcatct aatacgatac aaaggctatc tttctaattt gaaaaaggga
     1501 tcattaaaat aataagaaga aaatatgtca aaaggtaaaa aagtaaattc ttctatccaa
     1561 atatagaaaa attgaatcta gaaaaccgcc cgacaataaa tttcattaac tcagttgacc
     1621 gaaaatgaag tagataccaa aaatttatca agagagcaag tagagaagtg agtatattca
     1681 taagagaaat agctgtaacg aattattagg ttaatgcaaa tgcttattta tactccgtat
     1741 aactttctca gaaaaaatga taccaataat gacttgctag tactgtaaat ccgtataata
     1801 tcatctaatc aaaatggtgt tccatttgca tctgtcatcg taatcgatcc ttcgggtgac
     1861 actcgataaa aaccaacgct tccagatcct ccttgggaac ggatttgttt gctggaagct
     1921 gtgaacaaat aatctcgatc aattttttga taaaagctaa taacaatatc gtcactttgt
     1981 aattcggaac ggtgggcaat aagaaataga agtgctttgt cagagttttc taatggaaga
     2041 gaaggtacag tgctttcttg catttcagat gttgaagaaa tgctaaacga ctgaatactt
     2101 gattggctat gttgcgaatc tacattacca gtagaagtat tagtaatgga agtagtagaa
     2161 gtacttttag ttgaaccaac ctcagttgtt gaaatggctg ctgaagattc tttaacagaa
     2221 ttctttgttt tatatccaca ggcagaaaaa agtattacag ttcccaacaa gcctgcgtaa
     2281 atccctttat gcatgatagc tcctcctaaa atagattatc tttattcagt atatcactta
     2341 aacaaagaaa agcagatggt ttaaaatgaa aaaaccttcc caataaaggg aaggttcatg
     2401 aagataataa cttttttaat aattatagct ttctaatatc tttcatcaac ttttctagta
     2461 atcattggga aaaatttcaa gcagtagatc gcacaaatac ctacgacgat ataaatgatc
     2521 ttcgcaaaaa tagttgttga accaccagca atcatagcta ctaaatcaag ttcgaacaag
     2581 cctaccaaca gccagttcaa ccctcccaca atcaataaag ttaatgcaat agcatctaag
     2641 ttttcattag aattctcctt tcttaaatga taaaacaatt atatatcaaa aagagaaaca
     2701 ttgcttatat aacgctcagg aattttagca atctatgcaa aaagatgaaa attttttttg
     2761 ctcttccatt agtacacatt ttttagctga agctgtaaat ttcatgtctt aatttttttt
     2821 agtgagcttt tatactggat ttgtaagaaa aaagaaggag aggatcacat atgtcggatt
     2881 ggttggatat tgcaggaaaa gtagtaattg taactggagg ttcctcagga attggaagaa
     2941 gtatcgtcga aaatttgttg aagcagaatg cacaagtagc gaattttgat gtaactgaat
     3001 gccgtataca gcatgaaaac ctactatctt taaaagtcga tgtgtcttct aaaacggaca
     3061 tagaagaagg gatatataaa gtaatgaaac atttcaagac gatcgatggt ctagtcaata
     3121 atgcaggaat aaatattcct tctcttctaa tagatagaaa tcatccaaaa agcaagtatg
     3181 aattatcaga acaagttttt gataagatga tcgctgtcaa tcaaaaaagt gtatatttga
     3241 tgagccaagc agttggaaga atcttggtgc aaaagggatc aggagtgatc gtgaatcttt
     3301 cttctgaatc aggattggaa ggatcagaag gacagagctg ttatgctgct acaaaagcag
     3361 cgatgaacag ttttactcgt tcttgggcaa aagagttagg aaagaggaat gttcgtgtgg
     3421 taggtgttgc accagggata ctggaagaaa ccggtttgag aacacaagaa tatgaagaag
     3481 ctctttctta tacgagaggt ataagcgtcg aacagctgag aaacggttac agtcgaacaa
     3541 gtacgatccc tctaggaagg agtggtaagc tgcaagaagt ggcggatcta gtctgctatt
     3601 atctttcaga aagatcaagt tatatcactg gagtcacgac taatatttca ggaggtaaaa
     3661 caagaggata aaggataggg gggacgcacg tgacgctagt aaacagatgg taccaattat
     3721 tgaaattact agtcactcac aagaaagttt caatccagga agtgcaaaaa gaaatcaaaa
     3781 ccagtaatca aaccataaaa aaagatattg gggagttgaa tgaagaaatt gccggtattg
     3841 caaaaatcat ccaaaaaaac aaacattttg aacttgaaat ttatgatttt gatttttttg
     3901 atgagatcat gcaaggaaaa ttgaaaacag ccagtgattt caattcggca tccaaaagaa
     3961 tcgcttattt actaaatagg ctgatcgaaa cagaggattt cttacgtatg gatgatttgt
     4021 ctgaagaagt cggtgtcagc agaggaacag tggtcaagga tctaaagaca ttaaaagaga
     4081 tgatcaatga ttttgatgta aagattacag gcacaccaaa taaaggacta agaataatag
     4141 gagatgagct agaattacga ctacttttat tttattttgt ttctccctac ttttcagaga
     4201 cgaaaacaga acagtttcta gaagaaaaac aagcaatcaa acattttcag aagaagacga
     4261 atgctagtaa acaagaaatc acccttttaa cgaaagttat cggtatttct ttgaatagaa
     4321 tctctagtaa ctatctgttg aagaagccca tcaatcgtta cagtgggtgt tttgaatata
     4381 tccaagaatt caatgaactg atcaatcagt tggaagaaat ctatgaacta actttgagcc
     4441 aatatgaaaa agattttatc agttttcctt tgaacatcat caacacaagt ataacgatga
     4501 taaggaaagc taactctgat ttgcgcttat atttcgaccc catgatgatg cgtattcgac
     4561 gattagatct cattgatctg gatgagtcct tcttatatca agagatgaaa cagcacctct
     4621 ctttattgat aaatcgggta atttttcgtt atcgattgac tgatttattt tatggtgaga
     4681 tagaaaaaaa gtatcctttt tcttaccaaa tcgctagcga atgcatacaa gcattagaag
     4741 ctatcttgca acataagatc tctaaagtag agatcagcta cctaacgttg tatttggagt
     4801 tagcatttcg atatcaaaaa gagcattttt cctctaaaaa agtagccatt gttcatacga
     4861 caggaaaagg aacagcatta atgatccaaa gacaaatcaa aaggatattg gggagggata
     4921 tacaaataac acatgtttca gaagaacaat atgaaaaagt agatctaaac aaatatttcg
     4981 ctgtttttac aacgattccg ttaaaaaatg taaatgaaga gacaccggtg atccatttga
     5041 ctaatctttt tgatgactct tggttaaggg cacaatggca aaaagcaaaa aaaaagcgat
     5101 tagccgggtt tcattctact gtttttttct atcaaatatg gaaagaaaaa aagacgtatc
     5161 aagaatattt aaacaaatta gtcgctcctt tgatcagagg ctattatgtg gatgaagaat
     5221 ttgaaaaaag gatcttgaaa agagaatatc agcaaagcac atttgttaac aaagaatttg
     5281 cttttcctca cacaaccaac cagctatctc aacacattgt tttatcagta gggctaataa
     5341 ctgatcaagg tttagcagaa acaggaggaa atggagttat ttttttattt gccatacctg
     5401 aagaaatgac ggctgaagtt gagaatgaat tatttgagct atacgatatc ctatttgaac
     5461 tcataaaaat gggaatagat gagtttattg aattagcacc gacacaagaa tcatttttaa
     5521 aactaatcaa aagtaaagga gagagacttc atgaatgata tgtatctatt catagttttc
     5581 gcagcttcag cttatgtgct gcaagcagtt atcagttgga agcaactaaa gcatttcaat
     5641 caaacatata gcgaactgcg aagaaaagga aaagtagcga ttggtaaacg acctgggaaa
     5701 atccgttcag gcacgattgt tatgctagct atagacgatc atgatcaagt tttagaagtc
     5761 agaaaaatgc aaggggttac atctttggca aaatttcatt cattacctgt ctatgcgggt
     5821 gaagatatcc attacatcga tcgttaccat ccctcagttc gagcggaaga tcgtttgaca
     5881 caagcagctt tagaaaatgc cagagaagta tacttacgaa tagaggcagg aaatgaaaaa
     5941 agtgaacaac cttcattgcc ttttattgct atgctcaata attttcggat atggaaaagt
     6001 acgatcaaag aaaaaaggag tgacaaacga tggatatcat aacaaaattt gctgagggat
     6061 ttatgaggct gttccaaaca ggtgcagaaa cattcataag ctggatgaca ggaatcgtac
     6121 cagttgtctt gatgctgatg gttgcaatga atacgctgat tgctttttta ggtgaagacc
     6181 gagtaacgaa agtagccaaa ttatcagcga aaaatccgct tactcgttac cttgtgttac
     6241 cgttcttatc tgcttttatg ttgggaaatc ctatgtcatt tacaatggct cgtttccttc
     6301 cagaatacta caaaccaagc tattatgctg ctcaagctca attttgtcat acgagcaatg
     6361 gtgtattccc ccatattaat cctggagaat tgtttgtatg gatggggatt gctcaaggga
     6421 tcgaaacctt agggctaaat tcgatggagc tggctatccg atacttgctt gtgggactgc
     6481 tgatgaactt tattggtggt tggataactg attttactac tggatttgta tgcagacagc
     6541 aaggaatcgt tcttagcaaa aaagtagagc tttcagttga ttagagaaag gagagtttta
     6601 aatgtatggt gatattaaga tcgtaagagg aaacggcggg tatggaggtc ctttgattat
     6661 taggccgaca aaagataaac acaagttcat ctatgtcaca ggtggaggtg agaggccaat
     6721 gatcgtagat aaaatagaag aactgacagg tatggagtct atcaatgggt tcaaaacatc
     6781 aatacctgat agtgaaatcg cgcttgcaat cgttgactgt ggagggactc ttagatgtgg
     6841 aatttatcct aaaaaaggga taccaaccat caatatcgtt cccacaggaa aaagtggccc
     6901 attagcacaa tatatcactg aagatattta tgtttcagca gtagggttag aacaaataca
     6961 gccactaatg gaaactgatg ataacaaaga aacagtaaat actgcatctc cagataaaaa
     7021 gtacaaatat gatacttcta aaaagataac cgagcaaaaa gcagagcagc aaaactggat
     7081 agcaaaaatt ggaatgggcg cgggaaaagt agttgctaca ttcaatcaat cagcaagaga
     7141 agcagtagat acgatgatcc ggacagtgat cccttttatg gctttcgttt cccttttgat
     7201 tggtgtgata caaggttctg ggatcggtaa tgtatttgct aacattatgg cacctttagc
     7261 aggaaatgca gttggattaa caatcattgg ctttatttgt tcactgccat ttttatctcc
     7321 tttgcttggt ccaggggcag ttattagcca agtgattgga acattgatcg gtgtagagat
     7381 tgggaaagga aatattcctc cccaattagc attaccggca ctatttgcta tcaatactca
     7441 aaatgcatgt gattttattc cagtcggtct aggtttggaa gaagcaaaag ctgagacagt
     7501 agaagtaggt gtaccatcag ttctttattc aagatttctt aacggcatcc cacgagttat
     7561 cattgcttgg gtagcaagtt ttggattata tagctg
//
LOCUS       DAFBSV010000108         7346 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.111, whole genome shotgun sequence.
ACCESSION   DAFBSV010000108 DAFBSV010000000
VERSION     DAFBSV010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7346
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.111"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            99..746
                     /locus_tag="LLB18_002512"
     CDS             99..746
                     /locus_tag="LLB18_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBK5245487.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    875..1091
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1139..3784
                     /locus_tag="LLB18_002513"
     CDS             1139..3784
                     /locus_tag="LLB18_002513"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBK5245488.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            4094..5407
                     /locus_tag="LLB18_002514"
     CDS             4094..5407
                     /locus_tag="LLB18_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBK5245489.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            5397..6050
                     /locus_tag="LLB18_002515"
     CDS             5397..6050
                     /locus_tag="LLB18_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBK5245490.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            6105..6776
                     /gene="radC"
                     /locus_tag="LLB18_002516"
     CDS             6105..6776
                     /gene="radC"
                     /locus_tag="LLB18_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBK5245491.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGIYKLVHINYIRKFTVILPSGNTIMLSIIERHNAFFSS
                     SEDSL"
     gene            complement(6671..>7346)
                     /locus_tag="LLB18_002517"
     CDS             complement(6671..>7346)
                     /locus_tag="LLB18_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBK5245492.1"
                     /translation="NNKNYCPPIIDKKLFYAVQKALPKNLKTNAKRDYIFKGLLKCSD
                     CQGSVAGQTIKARYKKKDGTESIYERTCYRCVKRRNNKLRCTNKRAFYEKNLERYIFE
                     ATKQKFEQIQINYSKKQPKIIKKKNSKKNIENKLDRLKKAYLNEVIDLEEYKKDREAL
                     MKELNEIEVEPAKIDIKNVEFILSKEFDEIYKESSEEEKNALWRSIIDNIIVFPDGNI
                     TVNFLI"
BASE COUNT         2386 a         1237 c         1534 g         2189 t
ORIGIN      
        1 atttgtctca cacccttttc cttcctactt gtaaccttgc tcccgtgtta gaaacatgtt
       61 acactaaata tgtgaaatta ttaacaagga gcgtcgttat gcgagaaaaa acagatacac
      121 tgccaaaagc aactgcgaaa agattacctt tatatttacg ctacttgaag atgctggatg
      181 actcaggtat aagtagaatc aaatcaaatg agttcagcga aatcacccaa attccttctg
      241 caacgatccg cagagacttc tcgcaattag gcgagctagg cagaagcgga tatggctatg
      301 atgtcccttt tcttatcgat gtattcaata atatccttaa tactaaagaa gaaaaacgaa
      361 tcgcattagt aggatatgga aatcttggca aagcattgaa acacaacaat tttagaagaa
      421 atgaaaatct aaatatcgtg tgcgtctttg ataatgatcc agcactgatc aatcgagtaa
      481 ttgatggaga aatgatctat ccgattgatc gtttcgcgga gatagccaaa gcaaaaaatg
      541 tgacagtagc aatctctacg gtaccaagta aatattcaca atctgctatt gatgaaattg
      601 tcaaaggaaa tgtaaccgct atacttaatt ttgcgcctga cagagtaact gtcccagctt
      661 atgtcaatgt tcaatacatt gatttgacaa ccgagttgca gacgcttatt tactttgatg
      721 agaattactc agaagttttt tcttaggaaa atttgagtag gcttattgat cttgcgagaa
      781 ctcgtcgtaa ttctttcaaa aattttttag tactaaatga agtggttttt tcacgaccac
      841 ttgttgacta aaaaaaaaaa ccattgtaga atgaagcata acgctgaaca agaggagtaa
      901 ctggcacatt cattcttaga gagagaacta tctgctgaaa ggttctcaat gacaaccagt
      961 gaaggtagct tgggagtttc tgtcttgaat ggagtagaga tagacgagtc gtgatcgtta
     1021 actcacttga gaggcaataa tgattgatta ttgcaattta ggtggtaccg cgtaaatcat
     1081 acgtcctaga atacgaaagt attttaggac gttttttagt ttaaaggagg aaaacagcat
     1141 gacggaagaa aataacctat caacaaaata taatccgcaa gaagttgaag ctggacgtta
     1201 tcagcattgg ttagaacaag atttgtttaa accgagcgga gataaaaaag caaaacctta
     1261 ttcaatcgta atcccgcccc caaatgttac tggaaaactt catttagggc atgcttggga
     1321 tacgaccttg caagatatgc tgattcgtca aaagagaatg caaggatatg atactttatg
     1381 gctgcctggt atggaccatg caggaatcgc gacacaagca aaagtagaag cgaagcttag
     1441 agagcaaggg atttctcgtt atgatctagg tcgtgaaaag ttcatcgatc aagtgtggga
     1501 atggaaagaa gagtatgcga gccacatccg cgaacagtgg gctaaaatgg gcttatcttt
     1561 agattacagt agggaacgtt ttacattaga tgatggatta tctgaagcag tacgtaaagt
     1621 ttttgttacc ttatacgaaa aaggtttgat ttatcgtggt gaatatatca tcaactggga
     1681 tcctcaagca cgaacagctc tatctgatat cgaagttatt cataaagata tcgaaggcgc
     1741 cttttatcat atgagctatg aactagcaga tggatcaggc gtagtagaaa ttgcgacaac
     1801 ccgtccagaa acgatgttgg gagatacggc gattgctgtt catccagaag acgagcgtta
     1861 tcaagcgctc atcggcaaaa aagtgattct acctttagtc aataaacaaa tcccaatcat
     1921 tgcagatgaa tatgtagata tggaattcgg gacaggtgta gtaaaaatca ctccagcaca
     1981 tgatccaaac gactttgagg taggtaatcg tcatgatctt ccacgcgtaa atgttatgga
     2041 tgatgatggt acgatgaatg aactagcagg aaaatatgct ggaatggaac gttttgctgc
     2101 tcgtaaagca atcgtgcaag atctgaaaga aatcggtcga ttgattaaaa tcgatacgat
     2161 gatccacagt gtgggtcatt ccgagcggac aggtgtcgtt gttgaacctc ggctgtctac
     2221 tcaatggttt gtaaaaatgg cgccgttagc gaaaaaagcc attgataacc aagaaacaga
     2281 tcaagcagtg gaattcttcc ctccaagatt caatcaaacg tttttacgtt ggatggaaaa
     2341 tgtccatgat tgggtaatct cacgacaatt atggtgggga catcaaattc ctgcatggta
     2401 tcacaaagaa acaggtgaaa tgtatgtagg gatggaagca ccagcggata gtgaaaactg
     2461 ggtacaagat cctgatgttt tagacacttg gtttagttca gctttgtggc ctttctcaac
     2521 aatgggctgg ccagatacgg aaagcgaaga ttataagcga tacttcccta ctagcacttt
     2581 agtaaccggt tatgacatca ttttcttctg ggtaagcaga atgattttcc aaagcttgga
     2641 atttactggc gaacgtccat ttgagaatgt cttgattcat ggattgattc gtgacgaaca
     2701 agggcggaag atgagtaaat cattaggtaa tggaatcgat ccgatggaag taatcgaaaa
     2761 gtatggagca gatgctctcc gctggttctt atcgaatggt tctgcaccag gacaagatgt
     2821 ccgcttcagc tatgaaaaaa tggatgcttc ttggaacttt atcaacaaaa tctggaatgc
     2881 ttcacgtttc gttatcatga atatcgaagg aatgaccgta gaagagatcg atttatctgg
     2941 agaaaaatca gtggctgacc ggtggatcct tactcgtttg aatgaaacga tcgaacgagt
     3001 aactgagcta tttgatcgtt ttgaatttgg tgaagcaggt cgacaactgt ataactttat
     3061 ctgggatgat ttttgtgact ggtacatcga aatgagtaaa gaagtacttt atggagatga
     3121 tgctgtttca aaacaaacca cccgtagcat cttagtccat acacttgatc agatcctacg
     3181 tttattgcat ccaatcatgc cattcgttac agaagaaata tgggaacata ttcctcatca
     3241 gggaaattct ctagtagtgg cagaatatcc tgttgtacgt ccagagtttg atgatgaaac
     3301 agcttctaaa gggatggaag tattgaaaga attgattcga gccgttcgaa atattcgttc
     3361 agaagtgaat acaccattgt ctaaaccaat tacgttgcta attaaaacaa acgatgctaa
     3421 aatcgatcaa tttttagttg aaaatacaag ctatatcgaa cgcttctgta atcccgaaga
     3481 gttgacgata tcaagtgaga tcactgcgcc agatctagcg atgtcagctg ttctgacagg
     3541 tgcagaaatc ttcttgccgt tagcaggatt gatcaatatt gaagaagaaa tcaaacgatt
     3601 agaaaaagaa ctggaaaagt ggacaagcga agtaaaacgt gtccaaggaa aactttctaa
     3661 tgaacgtttt gtttctaacg cgccggaaga agtagtagag gcagagcgtg caaaagaaaa
     3721 agattattta gagaagcaaa cggctgtcaa agaacgaatc gaaagtttgc gtactattca
     3781 ataagaatag aaaaagagag tgtgaaatca gctagctatt actaaaagct agctgattga
     3841 acatcgttac aggaaagagt ttgagcctca ctcttagctt cgattcataa ggagatgtga
     3901 cataaatttt gtcgcatctc ttttttagtc tactcttatt atgtaggaga aggagggagg
     3961 tggatcatgt atcaagagtc aataaagtag ttgataaaat cgttcctctc tctgtttctt
     4021 ttctctttgt catactttta tttttcttat gtgttctatt tgttataata aaagagaaat
     4081 gggggaattg ttgatgacga ttgaagaagc aatagaatgg atccatagtc gattaccatt
     4141 tggttcacgt cctggccttg accgagtcga agctttatta gaagtggtag ggcatccaga
     4201 gagaaaagta aaaacgatcc atatcgctgg aacaaacgga aaaggttcta ctgtagctta
     4261 tttgagaagc ctattagaag aggctgggct gacagtaggt acatttactt caccttatat
     4321 cgaaacgttc aatgaacgga tcgcaatcaa tggcaaaagc attccagaca atgatttgat
     4381 ccagcttgta aaaaaatatc agccactgat caaacaactt gatcaatttg aagcagtagc
     4441 tggtattact gaattcgaga cattaacagc aatggcattt gattattttt tgatgaagaa
     4501 agtggacgta gcgattatcg aagttggctt aggcggctta ttggattcta ccaatgtagc
     4561 tgtaccaatg ctgacgggaa taacaacgat tggacttgat cataccgaaa tacttggaga
     4621 tacaattgaa gaaatcgctg cacaaaaagc tggaatcatc aaacaaggcg ttccagtagt
     4681 aacaggaaat attgccccag aagcttttac tgtcatccaa caaacagcta aagcaaaaaa
     4741 tgcaccgctt tatgtatacg gggaaaatta taaaataaac tatctgcatc ctgatgagat
     4801 gtggggagaa gtatttgaat tttttaatga aataggaaag atccctcaat taaccactcc
     4861 gcttttaggg caacatcaag ctgaaaatgc aggagtagcc atcgaattgt attttgttta
     4921 ctgtcaattg gaaaagctgc ctttccgaga aaaagatgtt ttgaagggat tgaagaaatc
     4981 tcgatggcca ggaagaatgg agcgtttgag taacgagcca ttagttgttt tagatggtgc
     5041 ccataatacg catgcaatga accggcttgt tgagaatttg aaaaaagaat tcaaaggata
     5101 tcaaatcaac attttgtttt ccgccttacg aactaaaaat gttagagaaa tgctagaacg
     5161 attgcagcaa gtaccaaatg tccatattta tttgacgacc tttgaacatc caaaagccat
     5221 cgaattaagt gaagtatcag atttagcaag tgagagagta tcaatcgttt cattgtggca
     5281 attcggatta gcagatatat tggaaaagat gacaaatgaa gacgtattag ttgtgaccgg
     5341 ttcactttat ttcatttcag aagttcgcca tttattaata caattaggag gagatcatga
     5401 agtataatgc agtgattttt gacatggatg gtttgctgtt cgacacagag ttagtgtatt
     5461 acgaagccac acaagtagta gcagacaaga tgggttttcc ttatgataaa gacctgtatt
     5521 taaaattctt aggtgtttca gatgaagaag tatgggcgaa ttatcatatg attttctcgg
     5581 aatttggcaa aacaagtgta caaagattca tagatgattc ataccaggaa acgcttgaac
     5641 gtttttcgca aggagcggta caaatgaagc ccggtgtgtt ggaactcctc tcttttttag
     5701 aagaacatca gattcccaaa gttgtcgctt ccagtaacca acgagcagtc attgaacttt
     5761 tattgaagaa gaacaatctg tttgaacgat ttgagacgat tgtttctgca gaaaatgttc
     5821 aacgagcaaa accagaccca gaaattttct tgttagctaa tcagaagcta ggtacagcga
     5881 agaaagaaac attgatttta gaagattcac aaaatggtat tttagcagct tctgcggctg
     5941 agatcccggt agtcatggta ccagatctgc ttccaccatc ccaagaattg atcaaaaaaa
     6001 cagctggggt tgtttcttct ttacatgaaa tccctgcatt gttaaaataa aaatccatct
     6061 cttttcgtat cttattttag ataagataga aaggagatgt ttttttggga aaacgattga
     6121 tcaaagaagt acctactagc tctttaccaa gggaacgtat ggaaatttat ggcgcggaag
     6181 ctttatcgga tcaggagctt ttggcaatct tactgcgtac cggtcaacac ccttatagtg
     6241 tgatgtcgat tgctggaaat ctgttaaaaa cgtttggagg actggcctct ttacgacagg
     6301 ctactttgca tgagttagaa gagattcgag ggataggacg cgtgaaagca atcgaaatca
     6361 aagccttgat cgaattaggt cgacgaattc agacggatca tgaaagagcg gctccaccgg
     6421 ttcgtaccag ctacgaattg gcccagcaat tgattctgga aatgaaagat cacaaacaag
     6481 aacatttggt ttgtatttat ttggacacga agaatcaagt gatcttaaaa aaaacagtgt
     6541 tcatcggttc gctgaatcag tcagtcgctc atcctagaga aattttccat tatgctgtac
     6601 gttattgtgc agcaaggatc gttttagcgc ataatcatcc ttccggaata tataagttag
     6661 tacacataaa ttatataagg aaatttactg ttatattgcc atctggaaat actattatgt
     6721 tatcgataat tgaacgccat aatgcatttt tttcttcttc cgaagattct ttataaattt
     6781 catcgaattc ttttgataga ataaattcga cattttttat atctatttta gctggctcta
     6841 cttcaatttc atttaattct ttcattaaag cttctcgatc ttttttgtat tcctctaagt
     6901 ctataacttc attcaagtag gctttcttca atctatctaa tttattctca atatttttct
     6961 tactattttt ctttttaata atctttggtt gtttttttga atagtttatt tgtatttgtt
     7021 caaatttttg tttagtagct tcaaaaatat aacgttctaa atttttttcg taaaaagcgc
     7081 gcttatttgt gcaacgtaat ttattatttc ttcgttttac acatctataa caagtccttt
     7141 cgtatataga ttctgtaccg tcttttttct tatatcttgc tttaatagtt tgaccagcta
     7201 ctgatccctg acagtcagaa cattttaata aacctttaaa aatgtaatca cgttttgcat
     7261 ttgtttttaa atttttaggt aaggcttttt gaacagcata aaaaagtttt ttatcaataa
     7321 taggaggaca gtaattttta ttattt
//
LOCUS       DAFBSV010000109         7021 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.112, whole genome shotgun sequence.
ACCESSION   DAFBSV010000109 DAFBSV010000000
VERSION     DAFBSV010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7021
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.112"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            161..1102
                     /locus_tag="LLB18_002518"
     CDS             161..1102
                     /locus_tag="LLB18_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HBK5245493.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1171..1902
                     /locus_tag="LLB18_002519"
     CDS             1171..1902
                     /locus_tag="LLB18_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HBK5245494.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2046..4226
                     /locus_tag="LLB18_002520"
     CDS             2046..4226
                     /locus_tag="LLB18_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBK5245495.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4246..4728
                     /locus_tag="LLB18_002521"
     CDS             4246..4728
                     /locus_tag="LLB18_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HBK5245496.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            4744..5505
                     /locus_tag="LLB18_002522"
     CDS             4744..5505
                     /locus_tag="LLB18_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBK5245497.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            5636..6970
                     /locus_tag="LLB18_002523"
     CDS             5636..6970
                     /locus_tag="LLB18_002523"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBK5245498.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
BASE COUNT         2364 a         1229 c         1550 g         1878 t
ORIGIN      
        1 tttctgtgcg aaacaggaaa gcgaagtctt tttaattcaa ataataatat tatgtaaaca
       61 aaaaactttc catgcgtaat tatacacaag caaataaatc gtcaaatgcg aacgccttct
      121 ttatactgtt taggaacgaa aagaaggaag gaagaaatac atggattatc aagtactgct
      181 ttattacaat tatacaaaaa tcgaagaacc agaggaattt gccaaaaatc atttagcctt
      241 ttgcaaatct ttggatctta aaggtcgtat tctagtagct gaagaaggaa taaatggtac
      301 tgtgtctgga accgttgaaa acacgactgc ctatatgaaa gcaatgaaag ctgatcctcg
      361 atttgctgat acgatgttca agatcgatcc aagcgaagga catgccttta agaagatgtt
      421 tgtaagatac cgtccagagc ttgtaagttt aaagctagaa gaggacattg atccaaacca
      481 agtgacaggt gcctatcttt caccgcaaga atttaaagaa gctattttag atgaacagac
      541 agtggtgatt gatgcacgga atgattatga atatgacttg ggacattttc gaggggctgt
      601 acgcccagat atacgcagtt ttcgagagct tccagactgg atccgcgagc acaaagaaga
      661 atttatggaa aaacgggtag tgacctactg tactggtggc attcgttgcg agaagttttc
      721 tggttggctt gtccgtgaag gattcaaaga tgtcggacag ctgcatggcg gtattgctac
      781 ttatggtaag gatcctgaag tccaaggaga attatgggac ggcaagatgt atgtgtttga
      841 tgaacggatc gctgtcgata tcaaccaagt agataaacaa atcgtcggtc gcgactggtt
      901 tgacggaaca ccatgtgaac gatatatcaa ttgtagcaat cctgagtgca atcgtcagat
      961 tcttgcttcc attgaaaatg aagaaaaaca tttaggagca tgtagcatag agtgtgcgaa
     1021 acatccgcgc aatcgctatg ttcaagacca tggaatctct ccagaagaag cagaactgcg
     1081 gtttacagct ttaattaaat agaaaacaat agttttgatt gtcgaccatt tccaatatgc
     1141 gctatactag cgttgaggat ggtgatccac atgaaatcat tgatttatgc tattggggat
     1201 gtccatggca aacatgagct ttttgaaaaa cttattcact attatgatcc aaagatccat
     1261 cagcttgttt tattagggga tctcaatgat cgaggtcctc gtacaaaaga atgtttttta
     1321 ttaggaaagc aattagtcga agaaacagga gccatttacc tccggggaaa ccatgaagaa
     1381 tattttttgc aatttctgca atcaccggag gactggtatg cgccttatat gagaaatggt
     1441 ggaaaagaaa cgtttgaaag cctgattcac ccaggggcat cggaggaata ctccccaact
     1501 gaaatctcga tgatgatcca atcgagatat tcagaactga ttaaattttt agtccagcgc
     1561 cccttgtatt atgaatggga aaattatctt tttgtccatg ccggtgtgga tttgacaaag
     1621 aaagactggc gtaagacaag tctaagagac tttatttgga taagggaacc atttcatgaa
     1681 gggaaaaaca atacaggtaa gacaattgta tttggacata cgattacacc aatgctccat
     1741 ggagatatgc agacaacaga cctctggatt caggatcata aaatcggaat ggacggtggg
     1801 gctgtattcg gagggtcatt gcatggggtt gtttttgaca aggaaggtat tcttcaagat
     1861 attgaatatc agaacaacga aggaccttgg catggaatct gactaatgga aagaatgaag
     1921 gagctgtgac tttgttgcgg ctctttttat ttttatagag aatattgttt ctttcagtag
     1981 tttaacccag gataaaaagt atgatagaat aaagaagcaa tttttagcag aaaagaggca
     2041 ttttaatgac ggaaaatttg aaccagacga tcattcagct tgtacaaaaa gaactttcag
     2101 actatcgtcc taagcagttg actactgtac ttaatttgtt aaatgaagga aacactgttc
     2161 cttttatcgc gcgttaccga aaagaaatga ctggaagtct tgatgaagtc cagattcgtg
     2221 aaatcgaaga gcggtatgcc tatcttgaaa acttagaaaa acgtaaaact gaagtgattc
     2281 ggctaatcga tgaacaaggg aaactgactc ccgagttaga agcagaaatc acccaagccg
     2341 tgaaaatgca acaagtggaa gatttgtatc gtccatacaa acaaaaacga cggacaaaag
     2401 caacgattgc taaagaaaaa ggacttgaac cactcgcgaa gtggctgatg cagcttacag
     2461 atggagaggt gcaatctgaa gcagaaaaat atattgacaa agaaaaagaa gtctcttctg
     2521 ccgaagaagc gttgcacggt gctcatgaga ttattgctga acaagtcagc gataatgcaa
     2581 aatttcggac ttggattcgg tcttatacgt ataacaaagg tatgtatgtc agcaatgtca
     2641 aggatgagca agcagatgaa aaaggcgtat atgaaatgta ttatgacttt gcagaacccg
     2701 tccataaaat ggtttctcat cgaatattag ctactaatcg tggagaaaaa gaagatattc
     2761 tgaaagtatt ctttcaagta gatgaagcag caattttagc ttacttggat cgccaaatag
     2821 tcaaaaatcc tgcctctcct tcttcttcat tcgtcagaga agcctatcag gatagttata
     2881 aacgctttat tcagccagca atcgagcgag aactgcgcaa tgaattgact gaaaaggcag
     2941 atgagcaagc aatcgctatt ttcggcgaaa acctccgtaa tcttttgttg caaccgccac
     3001 taaaaggtaa agttgtcctg ggatttgatc cggcttatcg tactggatgt aaactagcag
     3061 tcgtagatgc gacagggaaa gttttagcaa tcgaagttat ttatcctcat aaacctgcag
     3121 cgcaagcaaa aagagaagct gctggaccag cttttatcca attaattaat aaatatcaag
     3181 tagatatggt agctatcgga aatggtacag ccagtcggga atctgaactt tttgtggctg
     3241 agcagttgaa atccgccgac cataaaacct attacgctat cgtcaacgaa gcaggcgctt
     3301 ctgtttactc cgctagcgaa attgcacgaa aagaatttcc gcatctacaa gttgaagaaa
     3361 gaagtgctgt ttctattgcc cgtcgcctgc aagatccttt agctgaatta gtcaaaatcg
     3421 atcctaaagc tgtcggagta ggccagtacc aacatgacgt ttctcaaaaa cgtttggctg
     3481 aacaattgga ttttgttgtg gaaacagcgg ttaaccaagt aggtgtggat gtgaatacag
     3541 caagcccgca gctcttgcag catatatcag gattgaataa aacaactgcc caaaacattg
     3601 tcatttatcg tgaagaaaac ggagaattca ccgcacgaac tcaattgaaa aaagtgccac
     3661 gcttaggacc aaaagcatat gaacaagcaa tcggattctt gcgagtccct ggtgggaaaa
     3721 acattttgga caacacaggt atccatcccg aaagttattc tattgcaaaa gaaatattaa
     3781 cttcagtcca actttcagaa aaagagcttg gtacagaaga agcagtagaa aaattgacac
     3841 gattatccgt agagaaactg gctgaaagcc tatcagtcgg agaagaaacg ttagccgata
     3901 ttttagctgg gctgacacaa cctggacgag atatgcgtga tgagatgcca gcgcccttat
     3961 tacgtacaga tgtattgagt atggaagact tgaaaccagg gatggaattg actggaacgg
     4021 tccgtaatgt cattgacttc ggcgcatttg ttgatatcgg tgtgaagcaa gacggacttg
     4081 tccatatatc gaaactcagc aaaaaattcg tcaagcatcc tacagatgtc gtgtcagtag
     4141 gagatatcgt aacagtttgg atagaacaag tcgatacgaa aaaaggcaga atcagtttga
     4201 cgatgctttc cccttatgaa gagtaacaat gaggagtaac aaaaattgac acaagaagaa
     4261 ctgcagcagt tagtagaaga gatatcatta aaaagcttcc agcttccttt caagcaccaa
     4321 gcaatgttca atccacgctt acgtacaact ggcgggcgct atcatttaaa cgatcatcat
     4381 ttagatttta atgcgaagct atttgaagag tcagacgaag agacgattgc aggaatcatc
     4441 aaacatgaac tttgccatta tcatcttcat ctagctggaa gagggtatca gcataaagat
     4501 atggatttca agtatctttt gaaaaaaaca ggagggttgc gctatgcacc agccttgacg
     4561 aagaaacaga taaagatgga gtattatcga tgccaagatt gttctgccac gatctgccgc
     4621 aagagaagaa tcgatgtacg caaatatcgt tgtggaagat gtcatggaga aatcaaatgg
     4681 attgagacaa aaagagaaga ctttaatgaa gcacaaaaaa tcagatgaaa ggatagaagg
     4741 cctttggaaa aaagtgagca gaggaatcta aaagactgga atcagctatt aaatttttta
     4801 gccgcacctg aagagggaaa ttttgaggaa ctgacggcac ctacacttat tttagctgga
     4861 aactgtcttc ctatcttagc tgataaagca gcacaaatgt atttaaatgg ccaagtagat
     4921 caattgtttt tggtcggagg ggtggggcat gcgactagaa tcctttatga gaattttgaa
     4981 aagcaaggat ttcattttga agatggcatg agtgaaagtg aaatctgtcg tcagtatcta
     5041 aaagaagtct atgatttgcc cgataaggct tttctgatag aatcgaagtc tacaaattct
     5101 ggagagaacg ccactttttc actggagatt cttcattcct taggagctgt accagaaaaa
     5161 atcttattga tgaatgatcc gacactgcaa cgcaggactc gagcaacttt tgagaaagta
     5221 tggcaaaatg aacaaactat tttcgcgaat gctgtgccat ttgtgccgga aatccttcac
     5281 ttttctgaag agatcatctt tacagcaaaa gaactgaatc atcaatggcc taaggaatat
     5341 ttccatgcgc tagtattagg agaaatggaa cgtctccatg acgatgagaa cggctatggt
     5401 ccgaaaggaa aagattttat tcctcacatt gatatatcag aggaagtttg gtcttcttac
     5461 accagaatta aagagtcaat aaaaacggat ttttctcgta cttgaccatt ttagcaagcg
     5521 aatcctcctt tccaaataaa tttggttgaa attttcaatc gtttataaga taatgaggag
     5581 cgtgttgaat gtaatagcta aaagaatgga cgctagataa gagaagagga ttcaaatgga
     5641 aaatcaaaat aaattgtatc attttgttgg tatcaaaggt tcaggaatga gctccttggc
     5701 tcttgtttta catgaacaag gtctaaatgt ccaaggatca gacattgaaa aatatttctt
     5761 tacacaaaga gatttagaaa aagcaaatat cacgattctg ccatttaacg cagataatgt
     5821 aaaaccaggg atgacgatca ttgcaggaaa tgcatttcct gattcacatg aagaaatcca
     5881 gcgagcaaaa gaattaggtt tggaagtgat tcgctatcac gactttattg gtcattttat
     5941 ccaaaattat acgagtatcg ctgtaacagg ctctcacgga aaaacaagta cgactggact
     6001 gctctctcat gtattgagtg gtgtccgtcc aacaagttat ctaattggag atggaacagg
     6061 acatggtgat ccgcaagcgg aattcttttc atttgaggcc tgtgaatatc gccgtcattt
     6121 ccttgcctat tcaccagact atgcaatcat gaccaatatc gattttgatc atccggatta
     6181 ttatacaagt atcgacgatg tatttacagc tttccaaaca atggctggac aagtgaaaaa
     6241 agctattttt gcgtatggtg acgatgctta tttacgcaaa ttaaaagcaa atgtgccgat
     6301 ttattattat ggtgtcacag aaaacgatga tatccaagca cgaaacatcg aacgcacaac
     6361 ttctggttct gcttttgatg tctatcatgg ggatgaattt gttgggcact tcactgtacc
     6421 agcattcggt aaacacaata tcttaaatgc tttaggtgtt attgcagtag cttatttcga
     6481 aaaactggat ctgaaagaag ttgcagaaga aatgctgact ttcccaggag taaaacgtcg
     6541 attcagtgaa aagatcgtag cagacatgac cgtagtcgat gattatgcgc atcaccctgc
     6601 agagatcaaa gcaacgattg atggcgcacg ccaaaaatat ccagataaag aaataattgc
     6661 agttttccaa ccccatacgt ttacgcgtac gattgcattg atggatgaat ttgcagaagc
     6721 acttgattta gctgataaag tttacttatg cgatattttt ggttcggctc gggaagaaca
     6781 aggaaacgtt aagattgaag accttggagc gaaaatcaaa aaaggtggag aagtcatcaa
     6841 agaaaataat gtatctccat tgttagatta tcatgatgca gtagtaatct tcatgggtgc
     6901 tggagatgtt caaaaatttg aacaagcgta tgaaaaactt ttaagcagca cgacgaaaaa
     6961 tgtactgtaa tacaattact gcagtgtcct tataaaaata gaaagagggg gagtggcaaa
     7021 a
//
LOCUS       DAFBSV010000110         6644 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.113, whole genome shotgun sequence.
ACCESSION   DAFBSV010000110 DAFBSV010000000
VERSION     DAFBSV010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.113"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..546
                     /locus_tag="LLB18_002524"
     CDS             <1..546
                     /locus_tag="LLB18_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBK5245499.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IKQKLNWQSPVQFRKTTVTVV"
     gene            complement(716..1678)
                     /locus_tag="LLB18_002525"
     CDS             complement(716..1678)
                     /locus_tag="LLB18_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5245500.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1680..3119)
                     /locus_tag="LLB18_002526"
     CDS             complement(1680..3119)
                     /locus_tag="LLB18_002526"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBK5245501.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            3304..5250
                     /locus_tag="LLB18_002527"
     CDS             3304..5250
                     /locus_tag="LLB18_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HBK5245502.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            5514..6386
                     /locus_tag="LLB18_002528"
     CDS             5514..6386
                     /locus_tag="LLB18_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBK5245503.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         2123 a         1144 c         1180 g         2197 t
ORIGIN      
        1 atccatcgtc gtttctacac cagtatctgc catcagaaaa tcacgacgga tacaactgaa
       61 tttaaatacc atgaagtgga tgccaaaggc attatccgtc aaaagaaatt gtatctagat
      121 ccttttatgg atatgttcaa tagtgagatt ttatcctatc gtatctctga aaagcccaat
      181 gcattagcgg taatggaagg tttggaggaa gctatccaga ccactaacga ttgtccctat
      241 cgtcgtacgt ttcactcaga tcaaggttgg gcgtatcaaa tgaaagctta tagaaacaaa
      301 ttgaaggagt acaaaatctt tcaaagcatg tctcggaaag ggaactgctt agataattca
      361 cttatggaga atttttttgg cttattaaaa caagagattt ttcacgggaa agtttataac
      421 tgtttcgagg aattaaaatc agccatcgat agctatatct attactacaa taatgaacgg
      481 ataaaacaga aattaaactg gcaaagtccc gtccaatttc gtaaaacaac cgtaacagtt
      541 gtgtaaaaat atcattttag agcatgaaaa aaggagtgga tttctccact ccaaaaaagt
      601 ctaacttttg ggggtcacta caagttgaca actccttttt gtttacaaat caattggata
      661 tctacaaatt gtattttcta acgaatttta tagacattaa aaaattaatt taacgttaaa
      721 tacttcctcc agaaagtatt gagattggta aaatataatc cttatttgtc ttttcgcctt
      781 taattttttt cagaagaata tcaacaataa gacttgcaat ttcatcaatt ggttgtctta
      841 ttgttgtcaa ttgtgggaaa aatttctcaa taaaagaggt accatcgtat ccaataattt
      901 ttaaatcttc tgggatatta agtttaagtt gatgagcaat tttcatagtg agaatggctg
      961 ttaaatcatc agaaacaaaa ataccatctg gtttgtgatt tataatagtt gactttattt
     1021 ccatttcacg acggatagta gacagattat taggaatttt gaaaattttt ccatttggat
     1081 tttgaaaaga aaaacctagt gcacgtaatt ctgtgggaga atccgtgtta tcatttcctg
     1141 taatcataat ggtattttga caaccatttt tttgtaaagt cttagctgca agttttcccc
     1201 cttcaaagtt atctgaagaa acaatggaaa cattaggagc taaatttcta tcaaaagcaa
     1261 caataggtgc tctcacacgc tcataatcag caattccaag attatggctt gatgagatta
     1321 tgccatcaac ttggttggct tcaagcattt caatgtattc tctctcttta gcaggatcat
     1381 tttgactatt gcaaataatc gttttatatc catgtttaaa taactctatt tcgagatact
     1441 caatgagttc agagtaaaag atattactaa tattaggaaa aataagacca ataagctgag
     1501 gtgactttcc ttgaagtcca cgtgctaaat tatttggttt ataaccaaga gttttcatag
     1561 cttcatgaac tttttgtttt gttttttctg ataaatatcc cttattatta atgacgcgtg
     1621 aaacggttgt tgggctaact ccagctaatt cagcgacatc agttaatttt gctaccattt
     1681 taatatttta attcaaagta ttttccagta ggttcgcctg atttgatttg aataccattt
     1741 tggtgatttt cagggaatac acgactagta aacacttttt ctcctttatt aataaaaatc
     1801 tcaatgattg agttatctac aaaaatgtta gcagttgttt ctttagtatc aattgagcat
     1861 tcacgaatcg taccaaagtc agtggcatat tgaatgcctg ctttgctgcg atctaaaata
     1921 atttttcctt ctttggtatc tacaatcaag ctaagtccat ttcctttact atcagagaaa
     1981 agaagtaact ccgatttctg atttggagga aaagttagtt caagctcata agtattattt
     2041 gtttctgctt ttgctgtaaa ttgttcagaa ctagcacgta atgatgtaat agcttctact
     2101 ggatattggt aaagtttacc atcttttatt gaaagttctt ttacaagact cattgctccc
     2161 tgataatcat acttatcagt tggataatcg atatcaggta gtccaatcca actgacaatc
     2221 agagcacgac catcaggagt attgaatcct tgagtcgcat acgcttcaaa tccataatca
     2281 agattttgaa tttctgaagc gcccacaagt tttacttttt ctatgtcaag cgattgacag
     2341 atcttaaaag tattcggata gatattccca taatttagct cagatttatc caacccttga
     2401 ggacaataaa tgagaacagg ttttttgtct acaaatacta gatttggaca ctcaatcatg
     2461 tattctgaac cagtgccgcc aaaatcaagg ttgccaactt cctcccatgt ttccacgtta
     2521 ttgtcatccg ctttgtaaag tttgataaag cctgattttt ctaaattttg tgctccaaca
     2581 atcgcataca attgtccttc ataattaaac atttgtggat cacgaaaatg atcagttaca
     2641 tcagcaggtt tatgaataag aacattctca cctttcgtaa tgttgtagtc tttatccatc
     2701 catgctccga tttgaagtgt atcacgttcc caattttcat ttcgaacgtt tcctgtatag
     2761 agtaagaata gattcccctc tatttcatat gcagaaccgg aataagcgcc gtggctatct
     2821 cgttttgtgt ctggaagaag ttctgctcct gttacatgaa aatgaactaa atcatctgat
     2881 tcattgtgta cccattcttt caacccatga gcagctccaa atggccaatt ttgataaaaa
     2941 agcgtatatt ttccgttaaa aaaagaaaaa ccattaggat cgtttaacaa tcctgtttta
     3001 ggttcgatat gatagctagc acgccaaggt gatcgtttta cattatcctt aattttatcc
     3061 atctcatctt tagtccaatc agaataagca cgatatcgta tttctcgagg taagttcata
     3121 ttttactcct tcaatttatc tttttacaac tagtatggta aacgttttcc gttgaaaaat
     3181 caatcatttc atttaaaaaa ataaactata tgacaaacgt ttgacatatt tttaagatat
     3241 gctaaaataa atttgcattt cagtgaaccg ttttcacgta aaaataaaaa aggagtgatt
     3301 cgaatgaatt acagtaaagt agcttccgac gtaatacaag cggtcggaaa agataacctt
     3361 attgcagctg cacactgcgc tacacgtctt cgtctcgtac taaaagatga cacgaaagtg
     3421 aatcaaaaag ctttagacga aaatccagat gtgaaaagca catttaaaat tgatggacaa
     3481 tatcaagtga ttatcggtgc aggtgatgtt aatttcgttt atgacgaact tatcaaaaaa
     3541 actggacttt cggaaatttc aacagatgat ttaaaacaaa ttgctagtaa agataaaaaa
     3601 ttcaacccca ttatggcatt aattaaatta ttatcagata tttttgttcc aattatacct
     3661 gcccttgttg caggtggttt attaatggca ttacaaaact ttttaacagc tgctggactt
     3721 tttggaccaa aatcaattga agaaatgtat cctgcgattg aaggtatttc ctcaatgatc
     3781 caactgatgt ccgctgcacc attcatgttc ttaccaattt tagtaggtat ttcagctgct
     3841 aaacgttttg gagcaaacca atttcttggt gctgcaattg gtatgatcat gacaacacca
     3901 gatcttggtg gctcaactga atattggaat atttttggtt atcatgtttc acaaacaaac
     3961 tatgcttatc aagttattcc agttttagca gctgtttgga tattatctat attagaaaaa
     4021 ttctttcata aaaaattgcc atcatctatt gactttacat tcacgccatt attatcagta
     4081 atgattactg gatttttgac tttcacagtt attggccctg taatgttatt gttgtctaat
     4141 ggaattacag acattattgt ttggctatat aacactactg gatttattgg aatgggtatt
     4201 tttggaggaa catattcact tatagtcatg actggtttac atcaatcatt tccagctatt
     4261 gaaactcaat tactttcagc gtggacaaat ggtatcggac atggagactt tatctttgta
     4321 gttgcatcta tggcaaacgt tgctcaaggt gctgcaacat ttgccatttg gttcttaact
     4381 aaaaattcta agacaaaaag tcttgcttcc tctgcgggtg tctcagcact tcttggaatt
     4441 acagagcctg ccttgttcgg agttaactta aaataccgct ttccattctt ttgtgcttta
     4501 attggttcag gaattgctac agcagtagca ggattactta aagtagttgc tgtttcactt
     4561 ggttcagcag gtttcttggg atttctttca attaatgcaa catctattcc attttacgta
     4621 ttgtgtgaat tgattagctt tgtagttgct tttgcaatta cttacttcta cggtaaaaca
     4681 aaagctgctg gtatctttaa agcagaagaa attgctgaac aaacaccagt taattcttca
     4741 aaagtagcaa caacagatcc aatatctact gatgttgaat caacacaaac aaaagtttca
     4801 tcagaaacaa ttgttagtcc catttctggt aaagtgatta gtctttcttc agtaaatgat
     4861 ccagtctttt catcagaagc tatgggaaaa gggattgcca ttaaaccaaa tggaaacacg
     4921 gtccattctc cagtagatgg tactattcaa ctcacgtttg aaactggaca tgcttatggt
     4981 attaaatcaa ataatggtgc tgaagttcta attcatattg gtattgatac tgtatcaatg
     5041 ggaggaaaag gatttacaca aaaagttact actaatcaaa aagttagaaa aggcgatatt
     5101 cttggagcat ttgaccgttc aatgattgag aaagaaggtc ttgatgatac aacaatgatt
     5161 attgtgacca atacttcgga ttattcagaa gtaaatatag tagctgaaaa tacagtcact
     5221 gagggtactg atttacttga aatcaaataa atatatttcc ctgagtaaag atggaatttt
     5281 ctttccaaaa tcaaataata tagattaatc aaatatttga gaataacatt ttatttaatc
     5341 ttttcatata tcaattgtat gaaaaattat tagaatttta aaaaatgata aaaattcaaa
     5401 aagaaaaaat agtagttatt tacttgtcat gttactaaat aaaaaaataa tttaaatatg
     5461 atatatagtc atttatttag tgatttcatt ctaaaataaa gggagaaatg tctatgctat
     5521 acggtgcaat tgaagcaggc ggcacaaaat ttgtgtgtgc cattggcgat gaagaaatga
     5581 cgatcaagga aagagtgagc tttccgacaa cgacacctga ggaaacaatg cctttagtca
     5641 ttgacttctt caaacaatac caagcagatt tagcagggat tgggattggc tcatttgggc
     5701 ctatcgatat ccatcgcgat tccgccactt atgggtacat tacctcgacc ccgaaattgg
     5761 catggcaaaa ttttgatttc atcggtacca tgaaaaaaga atttccgatc ccgatttctt
     5821 ggacaacaga tgtcaatgcg gctgcctatg gtgagtatgt cttcggcagt ggcaaaggat
     5881 tgagcagtgt cgtttactat acgatcggta cgggtgttgg cggcggtgcc ttacaagaag
     5941 ggcgctttat cgaagggttt agtcatccag aaatggggca tatgctcgtc gtccctcatc
     6001 caaaagatga ctttgctggc agctgtccat ttcatggcaa ctgtttagaa gggatggccg
     6061 ctggacccgc catcgaaaac cgcttaggga aaaaaggaca agaggttgca gaagatgatc
     6121 cttattggga aatcgaagcc tcctatattg ctcaatgtgc ctacaataca accttgatgt
     6181 tttctccaga tgtgatcatt tttggcggtg gtgtgatgaa acaacgccat atgctgcaaa
     6241 acgtccacga cgcatttgca aaattggtca atgggtatgt cgaaacacct gagttaagca
     6301 aatatatcgt gaccccagca ttagaagaca acgctggaac gctcggttgt ttggcattgg
     6361 ctcgagaagc ggtcttacat tcataaacga aaaaaggctc ttcgacattt agtgttggta
     6421 gagaaagata caactgaaaa tttagtcata accagttagg cagagtgctt aactggtttt
     6481 tgttttactt ggaagatcaa gccttgaatg agataaattc ttgctcgaaa gttatggaaa
     6541 tttcgatagc cgtaggccac ttgtattgtg caatagtttt ttacaaaaaa aagggggtgc
     6601 ggatattttt ttggaccttt ttaacaaata tatctttgct tctt
//
LOCUS       DAFBSV010000111         6643 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.114, whole genome shotgun sequence.
ACCESSION   DAFBSV010000111 DAFBSV010000000
VERSION     DAFBSV010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6643
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.114"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(1..859)
                     /locus_tag="LLB18_002529"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="LLB18_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="LLB18_002530"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="LLB18_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBK5245504.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="LLB18_002531"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="LLB18_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2143..2373)
                     /locus_tag="LLB18_002532"
     CDS             complement(2143..2373)
                     /locus_tag="LLB18_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HBK5245505.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(2603..3421)
                     /locus_tag="LLB18_002533"
     CDS             complement(2603..3421)
                     /locus_tag="LLB18_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBK5245506.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="LLB18_002534"
     CDS             3582..4271
                     /locus_tag="LLB18_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBK5245507.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="LLB18_002535"
     CDS             4285..5787
                     /locus_tag="LLB18_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK5245508.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="LLB18_002536"
     CDS             5800..6276
                     /locus_tag="LLB18_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK5245509.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="LLB18_002537"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="LLB18_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2172 a         1031 c         1204 g         2236 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgtagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttgttatcca aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atg
//
LOCUS       DAFBSV010000112         6530 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.115, whole genome shotgun sequence.
ACCESSION   DAFBSV010000112 DAFBSV010000000
VERSION     DAFBSV010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6530
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.115"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            118..1107
                     /locus_tag="LLB18_002538"
     CDS             118..1107
                     /locus_tag="LLB18_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBK5245510.1"
                     /translation="MRDKEMRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAG
                     QYLFDKELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGA
                     MTICLSNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWET
                     CLNEFDKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFME
                     MQWINSNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVL
                     DQADFDLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            1089..1550
                     /locus_tag="LLB18_002539"
     CDS             1089..1550
                     /locus_tag="LLB18_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBK5245511.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            1600..2064
                     /locus_tag="LLB18_002540"
     CDS             1600..2064
                     /locus_tag="LLB18_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5245512.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            2078..2827
                     /locus_tag="LLB18_002541"
     CDS             2078..2827
                     /locus_tag="LLB18_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK5245513.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            2827..3657
                     /locus_tag="LLB18_002542"
     CDS             2827..3657
                     /locus_tag="LLB18_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBK5245514.1"
                     /translation="MENSTEKKRLITKKDLHKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTPFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            3657..4304
                     /locus_tag="LLB18_002543"
     CDS             3657..4304
                     /locus_tag="LLB18_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBK5245515.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(4402..5178)
                     /locus_tag="LLB18_002544"
     CDS             complement(4402..5178)
                     /locus_tag="LLB18_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK5245516.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLTESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
     gene            5260..5403
                     /locus_tag="LLB18_002545"
                     /pseudo
     CDS             5260..5403
                     /locus_tag="LLB18_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608918.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
     gene            complement(5520..6530)
                     /locus_tag="LLB18_002546"
                     /pseudo
     CDS             complement(5520..6530)
                     /locus_tag="LLB18_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
BASE COUNT         2162 a          943 c         1187 g         2238 t
ORIGIN      
        1 attttattat ataaaattgt tataaaaaat tttttttgaa aaatagtatt gcaaaataaa
       61 gcaatttcat agataatagg tatcgtaaag ttatataact ttataatacc tattagagtg
      121 agggataaag aaatgagaca actacacaaa gaacagattg aaacagcaat ggcagcgtta
      181 aaggaaaaga caattgatca tgtatatttt acagcatgtg ggggttcaca agccgtttta
      241 atggctggtc aatatctatt tgataaagaa ttaactgtac cttgtcatgt ttatactgct
      301 aacgaattta actatgctat accaaaagga ttatctgaaa attctttagt tatcacttgt
      361 tcccattctg gcacaacacc agaaactgta gaagcaacaa aaaaagcaag agaatttgga
      421 gcaatgacta tttgtttatc taatgaagaa ggatctcctc tatgggaagc agctgaatat
      481 cctgttcact atgattgggg taaagatgtt gatgctagtg atttaaataa aggaattctt
      541 tatggtttat tatttaatat tttacttgtt ttagatggct ctaaaaaatg ggaaacttgc
      601 ttgaatgaat ttgataagtt aaatgatctt gttattgctg aaaagagcaa atttgaaata
      661 actgctaaag aatggggtaa aaaccaaaaa cgagataaaa ttatttacac aattggtagc
      721 ggtattaatt acggagaaat ttactccaca gcagcttgct ggttcatgga aatgcaatgg
      781 attaattcta atgctattca ttctggggaa tttttccatg gtccttttga aatcactgat
      841 tatgatgtac cattcatctt agtgaaaagt attggagata caagattttt agatcaacgg
      901 gtagaagact tcactaaaaa attcagtaat aaattaatgg ttttagacca agctgatttt
      961 gacttagaat ctatagatag tgtagcgaaa gaatatattg cagctgtact tagtggcgtt
     1021 gttattcgcc aaatggtaga agcgattgct tttgaaagag gccattcctt agatgttaga
     1081 cgctatatgt ggcaaatgaa atattaatta ataggaggtt gcaaaagatg gcaaatcaat
     1141 tatttcacat tgtgattaca acacattcta ccctttgtga gggttattta aaggcaacaa
     1201 aattaatttt aatgaatgac gccacaggta ttagtgctgt tccatttaaa gaaaatacta
     1261 gtccagatga ttttgaggag agtatgaaag aaataattag tcagcatcat ttgcaacctc
     1321 taattatttt aacggattta attggaggaa cacctaataa tgtttctatt aaacagttga
     1381 acaacaatag aattcaaatt attgctggga ttaatttacc tcttttactg gagttattaa
     1441 tggcccagtc agctggtaaa tctatagaag aaatagattt taaggaatta ctgaataact
     1501 ctcaaaaaag tatggttcat attaattcgc ttttaaaaga tgtcagttaa ggtggcaatt
     1561 tctattctat aaattttaaa aattgaagga ggaaatagaa tgattaaatt agtgcgtgta
     1621 gaccacagat tacttcatgg acaagtaata ttttcttgga ctaaacagta tgatattaac
     1681 catattattg tggctgataa caaagttcca ggagatccaa tgtctgtgat ggctttgaca
     1741 attgctaaac ctgctgattg caaattagac attgttaaaa ttagtgatgt taaagggatt
     1801 atggaaacat ccccaaatga taattacatg attttaatta aaggacctaa ggaagctttt
     1861 gaattagttc aaaatttacc agaaattaaa gaaattaatt ttggcggtgt gtctaagaaa
     1921 agcgagtcca aacaatatgg aaaggcagtc tttttaactc ctgaagaatt agaagccaca
     1981 aaaaaaattc ttgatcaaga agtgaaaata tttgtgcaac aagtcccatc ttcaagtatt
     2041 gaaaatgtag attttagtaa gtaagggggg aaaataaatg ttattaaaag ccattttatt
     2101 aggtttagtt ggtgtggtag ctgttattga ctccaggtta attggtcgac aaaatattgg
     2161 tagaccacta attttgagta cacttgccgg acttgtgcta ggtgacttgc atacagggat
     2221 tgttcttggg gcatctttag aattaatttc tatgggattc gtctcaattg gggcggctgg
     2281 acctcctaat atgcaacttg gtagtattat tgccactgct tttgcaattt taactaatag
     2341 tagtacagaa acagccttaa caatagctat cccagtggct gtagctggtg aatttatgag
     2401 tattatcatg cgtatgataa ttgctcaatt tggacatgct gcagataaag ccattgaaaa
     2461 taataaattt agaaaagctc aaattattca tatttattgg tcatttattt ttaatgcttt
     2521 tgtttacttt attccaatct ttttaacagt atattttggt gctgacgttg tggcagattt
     2581 agtagataaa attccagaaa tgattacaga cgccttgact gtctctggaa atatgctttc
     2641 cgcattaggg tttgcaatgc tattaagcac aatgttgagt aaaaaattat atccttactt
     2701 tatttttgga ttctttattg ttgcctattc aggtctttca ctaattggcg tgacaatttt
     2761 tgcagctctg attgcctttg taatggatca agttaaatat ggaaaaagag aagaggcgca
     2821 tggttaatgg aaaatagtac agaaaaaaaa cgtttaatca caaaaaaaga tcttcataag
     2881 atgtgtcttc gttcatggac aatcatgtgt tcgtggaatt atgaaagaca aatgcatatg
     2941 ggatttatgt atgggatggc gccaatttta aataaagttt ataaaaatga tgaagagaaa
     3001 aaaagagaag cttatactcg tcatatggca ttttttaact gtacgcctca aatgactcca
     3061 tttattatgg gactttgtgc ttctatggaa gaacaaaatg ctcaagcaga agaaggaaac
     3121 tttaatactg aatctatctc catgattaaa accagtttaa tgggtccttt tgctggaatt
     3181 ggtgattcat ttttccaagg tactttaaga attattacat ttgggattgg attgtctttt
     3241 gctaagcaag gtagtatttt aggaccgatt ttagctgttg gcctttttgc tataccttct
     3301 attttagctg ttttttacgg cggtaaatta ggatatgagt ctggcaataa ataccttact
     3361 aaattgtatc aagaaggtct tatggatcga gtaatgcaat ttgcttctat cattggtttg
     3421 gctgtagtag gtggaatggt ggctagcatg gtgccaattg tcaccccttt aaaattcact
     3481 acagggggaa cagaacttgt tttacaagac ttacttgatt ccattattcc tggattatta
     3541 ccacttgtat gtactttggg aatatataaa ttgattaaga aaaatgttag tacaaatatg
     3601 ctcttattag gttgtatttt ggcagggttt gttttaagta taataggtat cttataatga
     3661 ttaaggctct aatttttgat atggacggag ttttaattga tagcgagatt atgtatcaaa
     3721 agtgggtatt taatttttta aaacaagaaa atttaagcta tcctttgtat tcttatcaaa
     3781 aaaagattgg aactacagca agtatttttg atgatataga aaagtacaat gagggatgta
     3841 acagtttaga attgaaggga aaatttacta aatattggaa atcgcaaaag attgattact
     3901 tggatatttt tcctaatata ctaattgaac agcttgaatg gttaaaaaag aaaaaaataa
     3961 aaatggcaat tgcttcttcc agtccaatgg atactataaa tgaagttgtt accacttgta
     4021 aaatagagtc atattttgat tgtttaatta gcggaagaga tttgccagaa agtaaaccta
     4081 atcctactat attccttaaa gcttcagaac agctcagaat tccagttgaa gaatgtctgg
     4141 tgatagaaga ttcttataat ggtataaaag ctggtaaaag agcaaatatg aaggttcttg
     4201 caattaaaga taaacgtttt tctcaagatg taagtctagc agatgatgtt atttacgata
     4261 ttaaatatct gcgacaagaa gtacaggtga aatttggaat ataaataagt tttttgatgt
     4321 atttagagaa tattagtaaa aataaaaatc atgcccaaat ctaatcaaaa ttgattgctt
     4381 tgggtatgat ttcttttaat atcaatctat tactttagga tctgaatcat ttttatgcac
     4441 cgtatctaaa gtgatatttt ctgtgacttc aataacataa ctaattctat cacaacgaac
     4501 tgtggattga gaataatgaa atggttgatt atttttatct ttgccaacct tttctaaaat
     4561 aaatagcgga tctcctacta tacattgcaa taagtcggaa agctcaggtg ttgcagataa
     4621 accgtttatt tccataatag agctcgtagc tttgacatca tagtcatctt ctagaagttt
     4681 atataatgaa gtatattggc tacctttttc aaataaagtt ggaaattttt cttctgatgc
     4741 gaaaaaatta tcaattccca tcggggcacc gtcttcccac attaaacgtt taatattgta
     4801 aactctatca gttacattga tttgtaattt attagctaaa aactcatcag cctttataat
     4861 tttagaatgt aaaacagtat atctaatttt atgtcctcgg gtagaaagag aatcgctaaa
     4921 tccatgaact ccagctaatt ttaaactttc ttttttttga gttacaaagg tccctttccc
     4981 ccttaatcgt tcaactgttc cactttctgt taaaagttta aaagcttttc gaatggtaat
     5041 cttacttact ccataaattt tacataattc ttcttctgta ggtaattgct ctcctggaag
     5101 atattttttt tcacgaatat cgttacgtat agaagcttct acttgtagat ataatggtct
     5161 attatcttga aaattcatag tacactccct aaaaagttat acttcattat atcacaattt
     5221 attaaaataa aagattaaga tataaatata aatgaactag tctttgacta accaatgccc
     5281 gcttttgaaa gaaaacaaat tcattctgtt ttaagtaaaa atccttatgt taccactcat
     5341 tctgaagggg atgagcctta tcgctacttg gttgtggaac caagcgataa gacaatttta
     5401 taaattcaat attaattaaa ataaaaacaa acaaagtaga ttattttact ttgtttgttt
     5461 ttttattggg agcgtcaata attttgtgta aataactcgt ccttctgcaa aataatgggt
     5521 tactcagtaa acattgaagc taatgtatcc gtcacttgtt ggaagccttt atggcttcta
     5581 tttaagaatt tttgattgta tgtatcaaag atggatacta ggaaacgctc tagtgattct
     5641 tcattttgaa actgctcttt tctgcggctg tatttcttga tttgtttctt gaaagattcg
     5701 attaaattag ttgagtaaat gcttcggcgg ataccaggcg gaaactcata aaaagtcaat
     5761 aaatcttgat tttttatcag tgactgcgtc actttaggat aagttttttg ctacttctca
     5821 atcatactcc ctaaaaaggt atttgcctct tcctttgagc tagcttgata aacagcctta
     5881 aaatcatcac agatttcttt tcgatctttg acacgtactt tatgagcaat attacgggaa
     5941 acgtgaacac agcaatgttg gtatttagct ttaggataaa tctggtgaat cgtatctttc
     6001 atgcctttta agccatcggt aataaacagt aagacatcat gaacccctct ggagtaaatg
     6061 tcctgtaaca actcattcca aacgtaggtc gattcagtcg gagcaatcgc ataacttagt
     6121 acttctttag tgccgtcttc tcgtatacca atggcaatat agattgcttc tttggagacg
     6181 gtttgccgtt ttaaaggaat ataagtagca tccatgaaaa tagcgacata cttatcattt
     6241 agagttctaa ctttaaatgc atttacttct tcagtcagca ctttagtcat gttggacatg
     6301 gtttggggcg tgtagtgatg cccatacatt ttctcaatca agtctgcgat ttccgacatg
     6361 gtaatacctt ttcggaagag gtgaatgacg gtctcctcta agatatcatt cgtccgtcta
     6421 taagcaggaa cagtctgttg cttgaactcg ccgttgcggt cgcgcggaat ctggagatga
     6481 agttccccgt actcggtctt gaccgtacgg tcataggagc cgttacgaga
//
LOCUS       DAFBSV010000113         6474 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.116, whole genome shotgun sequence.
ACCESSION   DAFBSV010000113 DAFBSV010000000
VERSION     DAFBSV010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6474
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.116"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            127..579
                     /locus_tag="LLB18_002547"
     CDS             127..579
                     /locus_tag="LLB18_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245517.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            593..1282
                     /locus_tag="LLB18_002548"
     CDS             593..1282
                     /locus_tag="LLB18_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245518.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1407..3758
                     /locus_tag="LLB18_002549"
     CDS             1407..3758
                     /locus_tag="LLB18_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HBK5245519.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3838..4233
                     /locus_tag="LLB18_002550"
     CDS             3838..4233
                     /locus_tag="LLB18_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245520.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4558..5175
                     /locus_tag="LLB18_002551"
     CDS             4558..5175
                     /locus_tag="LLB18_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBK5245521.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5216..5515
                     /locus_tag="LLB18_002552"
     CDS             5216..5515
                     /locus_tag="LLB18_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HBK5245522.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5549..5716
                     /locus_tag="LLB18_002553"
     CDS             5549..5716
                     /locus_tag="LLB18_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBK5245523.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5761..6324)
                     /locus_tag="LLB18_002554"
     CDS             complement(5761..6324)
                     /locus_tag="LLB18_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBK5245524.1"
                     /translation="MIFKLRNRTEGLNIDKLFQEKASGKDTERPEFQKLLNYIREGDC
                     VIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGNELLDTAMFDMFLSL
                     LSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQKRLVFKTVVDMLKQ
                     GIPVAEIAKENGISRPTIYKIKKANDL"
     gene            complement(6352..>6474)
                     /locus_tag="LLB18_002555"
     CDS             complement(6352..>6474)
                     /locus_tag="LLB18_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBK5245525.1"
                     /translation="SSTIKGMETIRGIYKKNRRNGTLFGFSVSTEIKVLMGITA"
BASE COUNT         2207 a          915 c         1282 g         2070 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc aattatctta tcgtagatat atattataaa tttaataaga aagcgaggtg
      121 agaatcgtga aaaaaacgat actaagtatt ttttcagtat ttacaatatt aattgggggc
      181 tattttcttt tgaatttaga ttctgttaat tcaaacgctc aaataaaaga tcaaagagta
      241 gctgaacata ataataaaaa aatgagtttg accaaaaata tctattctat gtcagatgaa
      301 gaattgtata aagaatttgg tgatttatcc ggggaacagt tagaagaaag tattccagga
      361 attagtgact cagataaaat tgttgtcttg tctgctggtg ggcaattaat gggagatggc
      421 aaatccgaat tagttagtta taaacaaaat cacagacagt ttattgatgt taatactgat
      481 tccaacgcta tttcgattaa ggatctaaaa gagcttttaa atagtaaaag aaatgaatta
      541 aagcagataa aagaaactaa ttcagtggaa ttagagtaaa ggaagattca ttatgaaaaa
      601 gatttttggt gtttctgttg ggctacttat gatgttaaca tttggaaatg cagtatatgc
      661 tgctgagaaa gaagttattt cagatccaga gcagtacgcc tcacgatact ttgctgattt
      721 tgaagaagaa gataaagtac ttgcattgcc agaaggtggt tttttaaaag gggaagctaa
      781 aattgtatct atggataatc cagatataat tcaaggttca tataattcag aaactgatcc
      841 tgcttcagtt tcagtgacag aagcaaaaaa aattgttgct gaaaaattca aaaatgatat
      901 tgaaactact ccaattatgc ctcgaggagc atttccaccc gatgttggta ctagcggaca
      961 ccttcttgta ctagcaggag gaggaagcta taaatcacag ccatttagtg gtgcgggatg
     1021 gcgttttgga ggtatgggtg taaaaccagc tgatggtaca ggcaactttt tacgttggaa
     1081 atcctacatt gacgatggaa gagtaggaaa tgtaaatcaa gccaacgcaa ctaaatctgg
     1141 ttctattcaa ggaatggcat tgtatgctcg tgaaggattc aaatactttg caccaaacgg
     1201 gcctggttgg acaatgaata taggtattta ttacacttat aatcctgttg caggtacgta
     1261 ttatgttgtt caaaatattt aataaaacag cacaaagaga tttctttgtg ctgttttatt
     1321 atttttagtt gttgacaaac actaaaatat aaaatataat caacacataa acgaacgtat
     1381 gttcggcaag aaagcagggg atttttatgg atgagatggt tttaagtact cagaaatggc
     1441 taaacaagaa atacagtaat gttacagggt ttgataaggt tccagaaaat gggcgaacag
     1501 ggtggcctac aatctatgga cttattgaag gactacaagt agaacttggt attactaatc
     1561 tagtagctaa ttttggacct accactgaaa aaatgtacga taatcaggtt actcctaaat
     1621 ggggcaaaaa tctacctaaa aatattgtat ttcttattca aggtgccttt tggtgtaagg
     1681 ggattaatcc aggtggcttc gatggggtat atactccata tttagatact gctgtaaaag
     1741 agttgcagac tgatgcaggg tttaatggaa gcgctgtaac tggagttttg gatgcgaaat
     1801 gggccaaagc gttatttgat atgagtgctt ttgttcttgt tcccggcgga gatagtaaaa
     1861 ttagaaaaat gcagcaatgg ttaaatgtaa attatttaga atacacggga ataatgcctt
     1921 gtgatggtat ttatcaaaga aattcaaatc aagcattaat ttttgcatta caagctgaac
     1981 taggatattc tcccagtgaa gcaacagggt cttatggtaa tgggacaact agtaaaactt
     2041 atcctgtgtc tgaaggtaac tcgggaaact atgtaagaat aattcaatat ggattatatg
     2101 ttaatggtta ttttgaagac ggtacattcg atggtatttt cactaaatat atgggtttag
     2161 aagtactggc attccgaaaa tttatggtat tgcctgaata tactgaaata gcagatgttg
     2221 ttgtaataaa aggactattg tctagcgctg gagatattag aagatctgca gatggcgcag
     2281 atacttctac gcaattaact agatctcaaa tccaaacatt ggttgataat gatataaaaa
     2341 tagttggtag atatcttact ggtactgttg gaattggaaa agatgaacga aataagtatc
     2401 taactacaga ggaattgaat aatatttttt ctaaaaattt atctgtgttt cctatctatc
     2461 aagatggagg tgcagcatta gcttatttta cttatgatcg tggcttatca gatggtaaga
     2521 aggctataga tgcagcaaaa aatctaaata taccattaac aacagttatt tattttgctg
     2581 ttgatctaga catgttaggg gaagaaattc ttgcatatgc tggagaatat tttaaggggg
     2641 tatctgctgt aatgtcatat agcgggtatc aaacgggtgt ttacggaaca agaaatgttt
     2701 gttctcaaat aatcaataac gggtatgctt cgtttgcatt tgtttcagat atgtcgactg
     2761 gttatagtgg gaatttaggt tttcctatgc ctagacaatg gtcttttgat caatttgttg
     2821 aatttaccat aggaagtggc aacggagctg ttggtatcga tttaatcgct acatcgggta
     2881 gagatagcgg atttaatgag ttatcaaatg atactaataa tgataattac attgccaaat
     2941 acaatcagaa ggttataaat cagatggtac gtgcgtatca atatctatca caagctggtc
     3001 ttgataatcc ttggaaccct catttgacat tttatagata tgtaaattat tctggtttgt
     3061 catgggacat catttcttct cctgtaacag agcatgatag aaaaatttat gatgaatata
     3121 ggaataaatt aactaatagc gagggcctgt ataattattt tatagatcct aatactggtt
     3181 caataatagg tttgcctcac ttaattgtga cgttacaatc acagatgttt ctagccgaca
     3241 caatcaatga tagtgtttct gactttgcag gttggttagg agatttaatg acttgctggg
     3301 gtgaagttaa gaaattagga atacaaatgg agcaaggtgt atttgcatta gtaggtacgg
     3361 ctgcaggtgg aacatttagt ctagaagatt tataccaaga tgttgacgcg gtaaatgttt
     3421 ataccttagc aaaaagaaat tctgattcaa cagctttatc ggctttaaaa acgtactatt
     3481 gtgataaggg tgctattgat agatttaatc aatttgttaa gaacagattt ggttcttcag
     3541 ataaaatcgc ttcagtaaca aatagtttat tagaaaatga cgaaacagtt gatatcttag
     3601 gtgtagggat aatttcattt ttcattgata aaatagttaa taattcactt gggacagatt
     3661 ttacttatct tgattttatt ggagatgagg ggaaagttgc aaatggattt tctgaaaaaa
     3721 ttattcaatt tcaagaaaat agaagtaaac ttaattaaga atcgtttact atttaaacag
     3781 tgtccttttc ctttttaaat atatacgata aaataagtat atgaattgta aaaggacatg
     3841 atgattatgg aagaaataga atggaataat ctgactcaaa ataataaaaa taattctgga
     3901 tgtggaatta tctttatgtt tgttatagtt ttgggaatag tagtactttt aataactgtc
     3961 aagatagtag attactttgc gaatactcct gaagaacaaa tacagagaaa acttcctgag
     4021 tttgaaagag taccacctta tgatccaaga gataattcat ttcaagtaaa aaaattaaaa
     4081 gagtctccaa atgaaatgtg gtttgaagtt acagttgaat caagcgactt caaagaaaaa
     4141 aagaaagaat acaattatat tgtaaaggca aaagtatcaa aaagatttat ttttaaccct
     4201 aaattagaaa tatatagtgt tgtaatagaa taatagtgtt aaaaaaattg taaaagttaa
     4261 agaagtcaaa ttctgatgtg aaaaataaaa tataccatgg aagacataaa agaaaaactg
     4321 gataactagt ttatttaatg gcagaccgtt aaggcctgcc atttttatgt attttagcgg
     4381 aataaatata atcatgcggg agtgtaaact tactgtttca aaaagtatac tttttgacat
     4441 gccttgattt tctttgttta tgtatggcat aataaccaca taatacaatt tgaaacgttt
     4501 ctgatttaat ctgattgttt tgaaacaatt ttagtgaaaa aagggtagat aaaaacgatg
     4561 agaaaatttt tttatatccg ggtcagtagt tatgatcaat cgatcgaacg acaactgatt
     4621 tccgcgaagg aattaggaat ccctgaagaa tatatatttg tagaaaaagc cagcggcaaa
     4681 gattttaaac gccctgaata tcaattaatg aaacggatgt ttcgaaaagg agatttactc
     4741 tatctacaat cattagatag actaggcaga aataaacaaa tgattttaga agaatggcga
     4801 gaattaacta aggaaaagca gattgatatt tctgtgttag acatgcctct gttagatact
     4861 gctagttaca agcaactaga tgggttagag acgcttatct ctgacttaat tctgcaatta
     4921 ctcagctata tggccgaaga cgagcggaaa cgaattaata gccggcaaag agaaggcgta
     4981 gaagctgcga aacaaaaggg tgtaaaattc ggcagaaaga aaattgcttt acctcctgaa
     5041 tttcctgcga tctattctga ctggaaagca ggaaagataa ctgcagtcta tgctatggat
     5101 caattgggca tgaaacgaaa taccttttat cgacgggtga aagaatatga acataccttg
     5161 caccactttt cttgatagat ataacagcta ttagacggga agggagagtt tgaaaatgga
     5221 cttaacgaat caaagggtcg tttttactgg aacgctgcag caaatgacac gaacccaagc
     5281 catcggtttg gttcactctt taaacggcca ttgtcaatca agtgttactt caaaaacaaa
     5341 tttcctggtt tgtggtcagt attctaagtc gttgtttgat gattctctct atacaaaaaa
     5401 ggaacaaacc gcgcgggact tgattgcgtt aggtcatgag attaccattt tatcagaagt
     5461 cgaattttat gcgttaatta gtcaacagtt gaaagaatgg caacggtatt tataatcgtt
     5521 agtaaaattt acaaggagga aaatttttat gaagcgaaaa tcttatgatc gttggggcat
     5581 tgaaataact agttttaatc gaaatattgc ttttcacgtg gagtgtgact gtggggaatt
     5641 agcaaaaagt gtttatcaaa aaaattactt ttactgtcct aaatgccatc gccgatacgg
     5701 ggtacatgga acatagaaac gaaatagtgc ggtagaaaag cgaatgaatg tagtatattt
     5761 ctacaaatca ttcgctttct ttattttata aatagttggt cgagagatcc cgttttcttt
     5821 tgcaatctct gcaactggaa tgccttgctt taacatgtcc accacggttt taaaaactaa
     5881 gcgtttttgc ggatctgttg agttaataga atactcgatt ggtcgtccct tatatcggcc
     5941 ggctttttga gccaataata ctccttgccg ctgacgttca cgaattttct cacgctcgtt
     6001 ttgtgcaata taacttagca gtgataaaaa catatcgaac atagcggtat ccaggagttc
     6061 atttccagta ttaaaatcta aaaactgtgc atctaatatt tttaacgcta cttttttctg
     6121 tttcataaaa gcaactgtat tttttatatc ttcataatct cttcctaaac gatctagtga
     6181 tgtaacgatg acgcaatcac cttcacggat ataatttagt aatttttgaa actcaggacg
     6241 ctcagtatct ttaccactgg ctttttcttg gaataattta tcaatgttaa gtccttcggt
     6301 tctgttgcga agtttgaaaa tcaaacgcgc cctctctgaa ctccaaatat cttaggctgt
     6361 tattcccatt aataccttga tttcagtaga caccgaaaag ccgaagagcg ttccatttct
     6421 tcggttcttt ttatatattc ctcgaatggt ctccatgccc ttaatcgtgg aaga
//
LOCUS       DAFBSV010000114         6458 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.117, whole genome shotgun sequence.
ACCESSION   DAFBSV010000114 DAFBSV010000000
VERSION     DAFBSV010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6458
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.117"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(105..560)
                     /locus_tag="LLB18_002556"
     CDS             complement(105..560)
                     /locus_tag="LLB18_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245526.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(714..1922)
                     /locus_tag="LLB18_002557"
     CDS             complement(714..1922)
                     /locus_tag="LLB18_002557"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBK5245527.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(2034..2366)
                     /locus_tag="LLB18_002558"
     CDS             complement(2034..2366)
                     /locus_tag="LLB18_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBK5245528.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            2514..3389
                     /locus_tag="LLB18_002559"
     CDS             2514..3389
                     /locus_tag="LLB18_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBK5245529.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(3471..4052)
                     /locus_tag="LLB18_002560"
     CDS             complement(3471..4052)
                     /locus_tag="LLB18_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HBK5245530.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(4058..5317)
                     /locus_tag="LLB18_002561"
     CDS             complement(4058..5317)
                     /locus_tag="LLB18_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBK5245531.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(5319..6365)
                     /locus_tag="LLB18_002562"
     CDS             complement(5319..6365)
                     /locus_tag="LLB18_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245532.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
BASE COUNT         1797 a         1337 c         1102 g         2222 t
ORIGIN      
        1 cttgtcacag tcccttattc tgaataaacg gtgtggaaga gacagcctat cagtagtaat
       61 aagacacatc tctttcacag cctcattttt gcgtaaaaat cgatttattc gaaaaattcc
      121 ccgtatacat cttctacacg ttgatctgga ttgatcacga tatacaagtt acctgttttt
      181 tcgctgattt ttgttgattg atattgattg tctaatcctt ctgttccttt atctagatat
      241 gggaagtaca caagatcagg tgtgccattt cggtaaagga tttccattcg ctcgatatct
      301 tcgtatttca atgcgcgatt aaacatgccc atttccagtc cgcctaggtt gatatcatgt
      361 gtcgcaactg cgtccccttc atggaagatt tcgattttaa atccagcaca cggatggatt
      421 tcaacaaatt cactgccatt gattcgtcca aaacttgttg tgatttgttt gatccaaaga
      481 tcgccgatat gacggcggtt gatcgtccag gtttctccat ttctaaaata aaattttagc
      541 gctgtcattt ctttactcat taaaaagact cctttatgat gtaatttatt cttgtactac
      601 ctcagtttag cacaaattta tgtaagtggt cacatcttat gttttttctt ctaatgacgt
      661 atctgcccac tttaagtagc caacaaagct gagcagatac agtctagtgt tttttaaatc
      721 aatttttctt tcgataaaaa atccaaaacc tgttttttat cattttttat tctttgttct
      781 acgacggctt tttcagctaa ttgcaaagct tcactaaccc acttaccagg tttttttcca
      841 gtttcttcta gcaagatttt accatctact gctaattcgc ttaatgactt gataggtaaa
      901 cgatcatagg attctcctac ggcatccatc tgaggtgttt cgtcaaaata gatcatcaat
      961 tcttctactt gcagtgcatg ttttttgcct aagaagtaca attcgaatgg ttccaaagct
     1021 ccagtttctc gttgtcgtag tccttggaca agtgcttgaa cgtctttaat catttggtta
     1081 gaacacttcc acgatttcaa aaaggaacga atctcatttt cttttagatc cagttggctg
     1141 atcaataatg cccatgcttg gctctcttct ttcaatggga cggatggtaa ttcagcaaaa
     1201 cgtaaaagtg cttcgccttc ttctttcaaa ccgggacagc aaatgtagca ctctgtttca
     1261 ataaatgcat ggattcccgc ggcccgttca tttcccaaga gcatcttgat gaattccaca
     1321 tttatacgtt ctacagatat tttacctaat agctcgtggt tttctttgat ggcgtagaag
     1381 gtttcttcct ctaatttgaa ccctagttga ctgacaaaac gcaacccgcg catcattcgt
     1441 aaggcatctt catggaaccg ctcatgagga ttgcctacag ctcgcaagat ctgttcttct
     1501 agatcttgca gaccatcgaa caaatcgatg atttctccat cttctttcaa agcaaacgca
     1561 ttgatcgtaa aatctcttct tttcaaatct tctgccaacg aacgaacgaa ttcgacatga
     1621 tctggtctac ggtagtcctg ataagttgat tccgtccgaa atgtggtgat ctcatattgt
     1681 tcatcatttt ctaataccaa cacagttcca tgttcgatcc caatatctat cgtttttgga
     1741 aaaagctgtt tgatttcttc tggaaatgcg cttgttgcga tatccacatc atggattggc
     1801 tggttcagca agatatcacg aacacttcca cctacaaaat aagcttcata tcctgcattc
     1861 tctaattttt tcagaactgg aattgccttt tggtattcca gaggtaattg ttttaatttc
     1921 atttttccaa cctttcctgc gtgtttcttg tcctgagata aagactcagt tgcatggtga
     1981 ctgtttgaca agtccgtttc agagtcttca aggccaggac cacttcatct tgtttactcg
     2041 tccttacgct caaagcgatt atggtctctt tgattgaatt tttccatgtt tttttcaaaa
     2101 acttcagtta agtcgatatt caatgaatta gccatgatca tcgtaacgaa taaaacatca
     2161 ccaagttctt ctgctaccga gttaactggt tcagaagcct ttttgctttt ttctccataa
     2221 gtgtggttga cttctcttgc caattcacct acttcttcag ttaatcgagc catctgagct
     2281 aatggagaga aataccccac cttgaattgc tggatatatt catccacttc ctgctgcata
     2341 ctgtataaag aacgcttttt atccatcttt ttccctccaa aactatctta ccaaaacttt
     2401 aacgcaaatc ctagataaga gcaattgaga aaatcgaatt tccatgctac atttaggaag
     2461 gaatttctaa atggaaattc tgtgaaaata cataattgaa agctggaatt catatggtca
     2521 aacgaaaaac agtaaaagaa gttcttttta tcattatagg aacaagtatt tatgcatttg
     2581 gtcttgttta cttgaacatc gctaatcatt tagcagaagg gggagtctca gggatcacct
     2641 tgatcttaag agctttattt ggtattgatc cagcttatac gactttatta atcaacatcc
     2701 cattgatttt actaggagga aagatcctcg gtaaacgttc cttggcctat actgttctag
     2761 gtacactttc tttgtcattc tttttatgga tctggcaaag ggttccacta gaaatcaatt
     2821 tacagcatga tctactgatc gtttctctac ttgcgggttt agttgcaggt gtaggaagcg
     2881 ggatcgtcta ccgcatgggt ggaacaacag gcggcagtga tattatcgct cggattttag
     2941 aacaaaatta cggcatcact atggggcgtt ccctattggc atttgatatc atcgtcttac
     3001 ttgcttcatt aacctatatc gacttgaaac gtatgatgta tacgttgatt gtttcgtatg
     3061 ttttcagtcg tgtgattgat tcgatcttag atggcggata ttctgcaaaa ggtctacttg
     3121 tcgtctccaa caaaagcgaa gagattgcac cactactgat gaccggtctg caaagaggtg
     3181 tgactttcct ttctggagaa ggcgcattct ctggtaattc aaaaaaaatc atctatatgg
     3241 tcgttagctc tagtgaatta actgaagcta agaggatcgt ccacgagatt gacgaaaaag
     3301 ctttcctttc aatcatcaat gtgcatgaag tggaagggca aggctttact tatttgaagc
     3361 cacagacaag attactgaaa aaactataag aaaaaagaca aagataggct atgaggaaag
     3421 attccacatc cagctgacct ttgtcttttt tagtactata ctatttttaa ctaattgtta
     3481 tgttcactta cccggttact tttcttttgt gtctgcaaaa ggatctttcg gttaacttca
     3541 tcagataatt tcaaaaaagc atccctatct ccatcttcta gtgcttgatc gatttgagca
     3601 taaagcattt ttagttttgc ctcttcttct ttttcttgaa aatatcgttc aattaattca
     3661 gtatcttctt cactgactga agaatcccaa gaagaaaatg gattgtcttc taagatagat
     3721 agatattctc ttgtctgcca agcattttcg aatatacatt ccacatataa aggctttttc
     3781 caattcaaac ggatttcatg aaaaatctgg tctgtgtccg taaattcttt tccctgcaaa
     3841 aacaatttca tgggttcccc ttcaacagat agatcactga tctgcagtcc tcgatccgca
     3901 aaattcgccc cttcaacaaa gtggacattg cttaaaatcg cttcatgatt ggcaagataa
     3961 ttcaagatcc aaaaaacttc tcttcggcta aaagatacat gattgaccat ccacgttaaa
     4021 aaattcttct tttcccgtac atcaattagc atttttctca cctctctgtt aggtcatcta
     4081 ataatgacag tgcctccata tctcctggtt caagtgttaa ataataagtc aataattctt
     4141 gcgctctttt cagctgccct tcttctctta agaaaaaggc atactctttc aagaaatctg
     4201 gttcatgtga tagttcatga taagcctgtt catagtgtac agctgcaacg gtaaagtctt
     4261 ctaattcatt ataagcatgg gctaggttcc attctgcata aggattagca gtttcttcca
     4321 tctgattgat cacttgtatc acatcttcat atctttcatc atccaagtaa agattactta
     4381 aagtaagtaa tgtttcatct tgtttgtctc ctacttctaa agctttcagt aaaagttctt
     4441 ctgctcgctg tctatcatgc agacggaaag cattttccga ggccaggtga taaagttcga
     4501 cttggtaagg attttctttg attccttctt ctaacactgt ttgtgcttct tcaatcattt
     4561 cttcttcttg aagagcttgt cctagatata gatataacga ttgataatgc ggattaactt
     4621 ctcgaagttc ttccagatag ttgattgcct gctgattttc tttcaattga agattcgtaa
     4681 aagctagctg gaacagtcga tcatctgtcc tttcttcttt cagtgcttct tctaaaggta
     4741 cgatagctgc ttcgaattct ccttgcatac ttaaggattg tcctaaacgt tcctgcatcg
     4801 agattcctga aatttcattt atcccgcttg ccaacaatgt ttcataaacc actgctgcct
     4861 ctttgaaacg atcaactgaa aaatacaatt cagctagcgc aaactggatc aatggttcat
     4921 caggaagcaa cccagctgct tctttcaatt ttgcttcact cacttcaggg attccgataa
     4981 cttggtacaa atcagctatc gccaataagc tttgcggata gtaatcactt tgcttatcca
     5041 ctttttccag gtattcaaaa gctaagtcga tctcattatc ttcgattgca atttctgcta
     5101 acgggatgtt cagtccgtca ttttctgggt attggttgat cagttgttca aaaatctgtt
     5161 ttgcttcgat caaaaagcca atagccagca attcttcgcc tagttcagct aatatatctg
     5221 ctgggtcttc ttttaatgct ttttctaaaa agatttgtgc ttgtgacaag tcttcatctg
     5281 ataaagcttg caacattttt tcgctatttg tattcatttc aattccctct tatctcactg
     5341 acgatttgtt gaaataccgt cattgttctc aataattctt tttcgtttgg atgttggtat
     5401 ccgtctatta tacctatttt ttctaaaaca agtatttttt tgcttttttc tgccaaaaaa
     5461 agaacttttt ccaaatactc catctttgaa atctgttcca gccagtggat tggatagcca
     5521 agcaagtcca gccacacaaa aaagtttttt agttggaaat caaaaggata tgcttggaga
     5581 ttccacacga aatgaaacat cattcctaaa aattttttca tactagcaga aagtagatgg
     5641 ccattttcgg tcagataaaa agcttgttca aacagtttac cataatttga caggttttct
     5701 gcctctaatt gataaaaata gatcatttct tcgatcatcc cggcaaacgg ccgagtcgtt
     5761 aattgctttt tatttggata gtttttatac agattttgca aaaaacgatg atcacaaatc
     5821 attccgcaac agataaaagt caaaaagtca atctgctttc cgtccacctg ccgctcgctg
     5881 attgtttgat cataaacgat gcgttctggc agattgatgg tttgcagcac tacacgattt
     5941 ggtagctgca aaatcgtccg ctgcggtgtt aatgctcggc ttagagaacg gatcgataca
     6001 gggatcatcc atagtgatga atcaagggtt gtatgttttt gaaaaaaacc tgccagatcc
     6061 atgatccctt catttccaaa tccgatgata aacatggatt gattttcggg atagcgtttg
     6121 acgaaatcaa gcaggttctt taattctgtt aaatgattgc attgagtgtt ggcacaaata
     6181 taccagtcat tgtttgcttg atttgcaaat aacgggttga tcttatctgc aaacaaatca
     6241 taatagcgct gattcgttaa aaataagatt ggctgatcaa tggaaagttc tcttagctga
     6301 ctgactagcg tttctccgta aaacactttc gtcaacgcat cttctacttg ataatcaagt
     6361 tccatacgca tccctcctct tcttattttt attttaccat tagtaagcaa attctagaaa
     6421 agataagagc aaagctcacc tcataacttg gaaataaa
//
LOCUS       DAFBSV010000115         6409 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.118, whole genome shotgun sequence.
ACCESSION   DAFBSV010000115 DAFBSV010000000
VERSION     DAFBSV010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6409
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.118"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(191..568)
                     /locus_tag="LLB18_002563"
     CDS             complement(191..568)
                     /locus_tag="LLB18_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HBK5245533.1"
                     /translation="MKKSYPVIFSAEENGYSVVFPDFAGATQGDNFEEAMSNAKEFLD
                     GILAYYIDEDISVPSPTDIHQLNNLGNNKIVSLIQSDPSPFIQKKTVRKNVTVPEWLV
                     ARGEKDKINFSKVLTDALLKIYE"
     gene            complement(614..802)
                     /locus_tag="LLB18_002564"
     CDS             complement(614..802)
                     /locus_tag="LLB18_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HBK5245534.1"
                     /translation="MPLTGKKMLKLAKKNGWKVVRITGSHHIVAKEGFPPVPIPVHSN
                     QDLKKGTEQKLLKDLGLK"
     gene            973..1515
                     /locus_tag="LLB18_002565"
     CDS             973..1515
                     /locus_tag="LLB18_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5245535.1"
                     /translation="MKFGGHFLNKKQDQEYYIEKLEKENLELKERIRYYETKFCKRGD
                     CMKPNPVETGKRIKSIRSNFGMTMEQFADLIGNAQKGNINNWERGFSLPNKERLIKIA
                     ELSNKTIDWIKWGTLEEYITSYLIGIGYELYIKDFPEIPHKVFKDIQEKYSDTFSLDK
                     DYELLDSIIKNIFTKYYSNG"
     gene            1710..2606
                     /locus_tag="LLB18_002566"
     CDS             1710..2606
                     /locus_tag="LLB18_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5245536.1"
                     /translation="MEINLFEAGNRIKQIREKHGYTMADLGKLVDANSPSTINNWEKG
                     NNLPNRKRLEKIALLGGTSVEWIKYGDFSDYVYRLTQNIEEKILKEYGETTLNNYREA
                     LLDELTIEKITYEEDTKILAAAEKINTQNIFQEVKYMYSPDEDYRNIEVKPDLGLTDD
                     NKNIKMIGQRIRKIRKKENITLEEFGKLFSPTADKAVISNWENGKNLPNSERIKKIAE
                     IGGVSELYLMTGVDSSVAESMYFLSEVALDALERLSIEEVNRIIESFAGYLNVISKID
                     DPDKREISLNAICQLSLLDKMG"
     gene            2655..4037
                     /locus_tag="LLB18_002567"
     CDS             2655..4037
                     /locus_tag="LLB18_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5245537.1"
                     /translation="MKPNLSLTSERIRKIIESKGLTLERFGDLIGDTPISSVNNWLRG
                     VSLPNKNRLLTIANIGNTSVDWIKWGTLEEYIASYLIDSGYELYIKDFPEIPYKVFKD
                     IQEKYSDTFSLDKDYELLNPIIKFTIGGVTLNRIKFYIDSSKKTIKQISTETGINYTT
                     LTNYYRGERNPRNTETWNILADYFHVPVSYLMGLDETNVELKNLNIGNNIKNIRKSKN
                     MTQTDFAELMGLSRSYIGDLENNRSNPSIKTLEAIARALDVPIVALINDSSTDNIVEP
                     YESLTAENILLKQENEELKYEVESLRKRLYEIQQVVNQGAEKMIPNLKDVSKRIKYIR
                     KKLGMTMEQFGSHLSNSPKSTIATWESGRNIPSQKKLQLIAIVGETTTDWIKWGTLEE
                     YITSYLIGIGYELYIKDFPEIPHKVFKDIQEKYSDTFSLDKDYELLDSIIKNIFTKYY
                     SKEFEVTQIP"
     gene            4051..4833
                     /locus_tag="LLB18_002568"
     CDS             4051..4833
                     /locus_tag="LLB18_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5245538.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSNTFSLNKDYELLNPIIKNIFTKYYSKDFEDYRDIEVKPDPKKVGRKIRSIRK
                     KLGLTMQEFGYEVSNSPRSTVSTWEHGGNLPNKAKLKKIADIANCSVEDLLFDEGFIS
                     EKSQVKLINELKEENSKLKEKIKYYECLFDGIESLLNSRKNS"
     gene            4873..5484
                     /locus_tag="LLB18_002569"
     CDS             4873..5484
                     /locus_tag="LLB18_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBK5245539.1"
                     /translation="MLVGYARVSSDDQNLERQLEEFRKIGVEKVFAEKKSGRNTVERP
                     EFNKMLSFVREGDTLVFESLERLGRNSDEILETVSFIDKNGMGLMVLNLPILDTKFGD
                     PNLEKLVRSLVINIFSWTAQNEREEIKRKQKQGIAIAKKKGVYKGKPYEYSSTAKNPQ
                     KRFIYNEIVRMLGEGVPIKRIAEKTGTNRNLVYRIKKRISESD"
     gene            5928..6077
                     /locus_tag="LLB18_002570"
     CDS             5928..6077
                     /locus_tag="LLB18_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245540.1"
                     /translation="MKLEIKEVVCDWGIYVDGETYPFMIFNSKANAQEIMRIMELDNK
                     HERFD"
BASE COUNT         2464 a          875 c         1168 g         1902 t
ORIGIN      
        1 caaaactatg gtcaccaagg gataaccctg aaactgatga tcgctatatc ttactagtag
       61 ttaaacagtc taaatagtac tcatttattg tattgattct aagggaacct gcaataaatg
      121 agtactattt tacttttaat tccgctatct atgtcattag gcaactaaat tgttattaat
      181 atatttacgt ttactcgtat atttttagta acgcatctgt caaaacttta gaaaaattta
      241 ttttatcttt ttcccctcta gctactaacc attctgggac tgtgacgttt ttgcgtacgg
      301 tctttttttg gataaatgga gaaggatcac tttgaataag agaaacaatt ttgttattgc
      361 ccaaattatt tagttgatga atatctgttg gagaaggaac tgaaatatct tcatcaatat
      421 agtaagctag aatcccatca agaaattctt tagcattgga catagcttct tcaaaattat
      481 ctccttgtgt tgctccagca aaatcaggaa aaactactga gtagccattt tcttcagcag
      541 aaaaaattac agggtaactt tttttcattt ccaccactcc tttcgagtta atccaatgaa
      601 ctaaaggact gggctatttc agccctaagt cctttagtaa cttctgctct gtcccttttt
      661 ttaaatcctg attactatga acaggaatag gaacgggtgg gaatccttct ttggctacaa
      721 tatgatggct gccagttatc ctcaccactt tccaaccatt tttcttggct agtttgagca
      781 tttttttacc ggtaagtggc attcgcgact acctccttac aaatattatt atacgcatta
      841 tgcgtataaa ggtcaagagt ttttacatta aaagtagaat gtaagtgtca caatagggta
      901 taccctattg tatcatatgg taaagtacag tataataagg tttggaggtg taacactagg
      961 gtgtaacaca atgtgaaatt tggaggtcat tttttgaaca agaaacagga tcaagaatat
     1021 tatatagaaa aattggagaa agagaactta gaactcaaag agcgaataag atactatgaa
     1081 accaaattct gtaaaagagg tgattgtatg aaaccaaatc ctgttgaaac aggtaaaaga
     1141 attaaatcaa ttcgttctaa ttttggaatg actatggaac aatttgcaga tttaattgga
     1201 aatgctcaaa aaggaaatat taataattgg gaacgaggat tctcccttcc caacaaagaa
     1261 agattaatta aaattgctga attaagtaac aaaactatcg actggattaa atggggaact
     1321 ttagaagaat atataacttc ataccttatc ggtataggat atgagctata tattaaagac
     1381 tttccagaga tacctcacaa agtctttaaa gacattcaag aaaaatatag tgatacgttt
     1441 tcgttagata aagactatga attattggat tctataataa aaaatatatt tacaaaatat
     1501 tactcaaacg gttgaattga tagatggact caaagaagaa aattcaaagt taaaagagaa
     1561 gataaaatac tatgaatgtt tatttgatgg tatagagagt ctgctgaact cacgaaaaaa
     1621 tccctagttt ttatgaatga ccgttttgta aatctgattg aaatagattt atatgatttc
     1681 ggtatatgat atacattagg aggtgtcgaa tggaaataaa tctttttgag gctggtaatc
     1741 gaataaagca aatacgagaa aaacatggat atactatggc agacttaggt aaactggttg
     1801 atgccaatag tcctagcaca attaacaatt gggaaaaggg aaataactta cctaatagaa
     1861 agcgtcttga aaaaattgca ctattaggtg gtacttctgt tgaatggata aagtatggag
     1921 atttttccga ttatgtttat cgcttgacac aaaatataga ggaaaaaatt cttaaagagt
     1981 acggagagac tacactgaac aactaccgtg aagctcttct agatgaactt acgattgaaa
     2041 aaatcacata cgaagaagat acaaagatat tagcagctgc cgaaaaaatc aatacacaaa
     2101 atatttttca ggaggtgaag tacatgtatt ctcctgatga agattatcga aatatagaag
     2161 tcaaaccaga tttaggactg actgatgaca acaaaaatat taaaatgatt ggacaacgta
     2221 taaggaaaat aagaaaaaaa gagaatatta cattagaaga attcggcaaa ctattctctc
     2281 ctacagctga taaagctgtt ataagcaact gggaaaatgg taaaaacctt cctaactcag
     2341 aaagaattaa aaagattgca gaaattggcg gagtttctga actttatctt atgacgggtg
     2401 tcgattcaag cgtagcagaa tcaatgtatt ttctatctga agtagcattg gatgctttgg
     2461 aacgtctgtc aattgaggaa gtcaatagaa taattgaaag cttcgccggt tatcttaatg
     2521 tgatttcaaa aattgatgat ccagataagc gagaaatatc tctcaatgct atttgtcaac
     2581 tatcacttct cgataaaatg ggttgattca caaaaaatat tgaaagatta ctttactcac
     2641 gaggaggctt agctatgaaa cctaatctat cgttaactag tgaacgtatt agaaaaatta
     2701 tcgaatccaa aggtctgaca ttagaacgat tcggtgattt aattggcgac acaccaataa
     2761 gttctgttaa taattggctt agaggcgtgt ctttacccaa taaaaatagg cttttaacaa
     2821 ttgcaaatat tggaaacact agtgtagact ggattaaatg gggaactttg gaagaataca
     2881 tagcttcata ccttatagat tcaggttatg agctatatat taaagacttt ccagagatac
     2941 cttacaaagt ctttaaagac attcaagaaa aatatagtga tacgttttca ctagataaag
     3001 actatgagtt attgaatcct ataataaaat ttactatagg gggcgttact ttgaatagaa
     3061 taaaatttta tattgattcc agtaaaaaga ccattaaaca aattagtaca gaaactggta
     3121 ttaactatac aactcttacg aactattacc gtggtgagcg aaatcctaga aatactgaaa
     3181 catggaatat ccttgctgat tatttccatg ttcctgtaag ttatttgatg ggattagacg
     3241 aaacaaatgt tgaactcaaa aaccttaata ttggaaacaa catcaaaaat attagaaaaa
     3301 gtaaaaatat gacacaaact gattttgctg agttaatggg tctatcacga tcatatatag
     3361 gggatttaga aaacaacagg agtaatccca gtataaaaac actggaagct attgcaagag
     3421 cattggacgt tccgatagta gcattaatca acgattcttc tactgataat atagtagagc
     3481 cgtatgaaag tttgacagcc gaaaatatcc ttcttaaaca agaaaatgag gaattaaaat
     3541 atgaggtaga aagcttacga aaaagattgt atgaaatcca acaagtagta aatcaaggag
     3601 ctgaaaaaat gattcccaat ctaaaagacg taagtaaaag aatcaaatat atcagaaaaa
     3661 aattaggtat gactatggag caatttggtt ctcatttaag caactcacct aaaagtacaa
     3721 ttgctacttg ggaaagtggt agaaatatac cttctcagaa aaagttacag ctgattgcta
     3781 tagtaggaga aaccaccact gactggatta aatggggaac tttagaagag tatataactt
     3841 cataccttat cggtatagga tatgagctat atattaaaga ctttccagag atacctcaca
     3901 aagtctttaa agacattcaa gaaaaatata gtgatacgtt ttcgttagat aaagactatg
     3961 aattattgga ttctataata aaaaatatat ttacaaaata ttactcaaaa gaatttgaag
     4021 taacccaaat tccataagag aggtgattgt atgaagccaa atccttcaga agcaggaaaa
     4081 cgaatcaaac aattacgcct ttcatgtggt tttactatgg aagaacttgg aaggaaaata
     4141 gataattcac cacgtgcgac catatccaac tgggaacgtg ggaccaattt accaaatcca
     4201 caaaagctga aattattatc aactatcact aattcaacaa ttgactggat taaatgggga
     4261 actttagaag aatatataac ttcatacctt atcgatatag ggtatgagct atatattaag
     4321 gactttccag aaatacctca caaagtcttt aaagacattc aagaaagata tagtaatacg
     4381 ttttcgctaa ataaagacta tgagttattg aatcctataa taaaaaatat atttacaaaa
     4441 tattactcaa aagattttga agattatcga gacatagaag ttaaaccaga ccctaaaaag
     4501 gtagggagaa aaattcgttc tattagaaaa aaattaggac ttactatgca ggaatttggg
     4561 tacgaggttt ctaattctcc tagaagcact gtgtcaacat gggaacatgg tggtaactta
     4621 ccgaacaaag ccaaactaaa aaaaattgca gacattgcga attgtagtgt agaagatttg
     4681 ctttttgatg aaggctttat ttctgaaaaa tcccaagtta aattgataaa tgaactcaaa
     4741 gaagaaaatt caaagctaaa agaaaaaata aaatactatg aatgtttatt tgatggtata
     4801 gagagtctgc tgaactcacg aaaaaattcc tagttaatta aactagagta aaattatttg
     4861 taggtgttaa atatgttagt tggctatgca cgagtcagtt cagatgatca aaatttggaa
     4921 agacagcttg aagaatttag aaaaattggt gtcgaaaaag tatttgctga gaaaaaatct
     4981 ggacgtaaca cagtagaacg gccagagttc aataaaatgt tgtcatttgt cagagaaggg
     5041 gatacgcttg tttttgagtc gcttgaacgc ttaggaagaa attctgatga aatactagaa
     5101 acagtatctt ttatagataa aaatggtatg ggcttaatgg ttttgaattt accaatttta
     5161 gatacaaaat ttggtgatcc aaacttagaa aaacttgtta gaagcttagt aattaacatt
     5221 ttttcttgga cggctcaaaa tgagagggag gaaattaaga gaaaacaaaa acaaggaata
     5281 gcaattgcga agaagaaagg agtctataaa ggaaaaccct acgaatattc ttctactgca
     5341 aagaatccac aaaagaggtt tatctataat gaaatagtaa gaatgcttgg agaaggtgtt
     5401 ccgattaagc gaattgcaga aaaaacagga acaaatagaa atttagtcta tagaataaag
     5461 aaaagaataa gtgaatctga ttgattttaa gttctttgag aaatcaatgt tacgagagaa
     5521 ggattctaag cctgtttcaa acttttaagg tgtacaatta tacaaagaag cttctaaaca
     5581 aaagaattaa ttttgtggca gtcaagtaac gacagaaata gaaaagaaag aggctatgcg
     5641 agagtgaatc aacaagttaa ttgggttaat gattttgaaa aagaatttcg actgaaattt
     5701 tttggaaatc ctacagcaga aagtacagaa gaaaaaaatt atgactggtc agaattttag
     5761 gttgcatatt cgattcaata agtgttgaag ataatagttc tcttacgcca cagtatacaa
     5821 cgttagaata tgacgaaaac agattcaata catttccttg caataccatt caagaatcaa
     5881 ttgataagca tgagtgataa ttgattatct acaggaaggt gttttttatg aaactagaga
     5941 tcaaagaagt tgtctgcgat tggggaattt atgtagacgg agaaacatat ccatttatga
     6001 tttttaatag taaagcaaat gcacaagaga taatgcgtat catggagttg gataataagc
     6061 acgaaagatt tgattaagta aaaaaatgga gaatgaatgt gaagcagtgg aataccaaaa
     6121 aacatgcgcc aataataagt atattttagg tgcaatggga ttaggtaaat cagcttctat
     6181 taaacaggtc tacgaagaat cacaggagaa ttgcgtatat gaaaattcga attaaagagt
     6241 gagaatatgt gggagctaat ttatttagtt ttatacttaa taggaaaatc aactgaattt
     6301 gtatataaca ataaggtaat atttatattg ttcttaatag tttgtattat cgtatttgat
     6361 gtctatgatt tactaattca taagaatgaa aatagtaata ttggtagaa
//
LOCUS       DAFBSV010000116         6359 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.119, whole genome shotgun sequence.
ACCESSION   DAFBSV010000116 DAFBSV010000000
VERSION     DAFBSV010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.119"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(1..669)
                     /locus_tag="LLB18_002571"
                     /pseudo
     CDS             complement(1..669)
                     /locus_tag="LLB18_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            690..1892
                     /locus_tag="LLB18_002572"
     CDS             690..1892
                     /locus_tag="LLB18_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
                     /protein_id="HBK5245541.1"
                     /translation="MCTKLLQNTAHKNPYKTVDEATQLDLVIVVNQLLTGYDSKWVNT
                     LYLDKSLEYQNIIQAFSRTNRLNGPEKPFGTIRYYRKAHTMEQNIEEAIELYSGKQAK
                     GLFVEKLYNNLEKLNDIFEEIKSVFNISGIENFSHLPEVPGEIKQFVNLYNQLIHCYE
                     SAMIQGFTWAKSTYEIQDYEPITVVITEYEFNILAQRYSEIEREPRDGNDSIAYDIDY
                     QLPEGSRSRINYEYLNTNFKKYMNIKEERDSNLIQSLLNDLHRTFAQLPVELQPYAEM
                     ILNDVNNGELVIKEGWEFTDYLNEYQLSEEDDFIQDLVDSTNINEALLREMLDLRLTE
                     VNINEYSRFDKLKSSVNVGHFSGYIEKNLGKMVIPIKVNMLIDRLLRAFLLEDVFDVT
                     EYIKNYFN"
     gene            2625..3593
                     /locus_tag="LLB18_002573"
     CDS             2625..3593
                     /locus_tag="LLB18_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBK5245542.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADARNHDLDVRRYMGKVEY"
     gene            3604..4419
                     /locus_tag="LLB18_002574"
     CDS             3604..4419
                     /locus_tag="LLB18_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HBK5245543.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKKIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            4487..5197
                     /locus_tag="LLB18_002575"
     CDS             4487..5197
                     /locus_tag="LLB18_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK5245544.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYVMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            5233..>6359
                     /locus_tag="LLB18_002576"
     CDS             5233..>6359
                     /locus_tag="LLB18_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBK5245545.1"
                     /translation="MKQILRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINYFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIK"
BASE COUNT         2152 a          969 c         1298 g         1940 t
ORIGIN      
        1 cagcccctca gtgacgccgt ttgagtggga caccttaaag gcatttgaaa tacccgattg
       61 gtagcgatgg aagatcgtga atttcttttt aaacgactga ggtaacgtag atgaaattgt
      121 tttaagggtt tcttgaaagc ctaccgtatc tcgtttaacg aaataatagc gtaataattg
      181 acaaaaatga tacgcagttc gcaattcttc gttgtagctt aacagctcat taacgatttc
      241 tgtttgacta attggtcgtt taaacagtcg atgataatgc cgtttgagtg cctcccatgt
      301 cgtggaatct ttgagtaaga gtttccaata tcgcttgagc cgacggtact tcttctgatt
      361 ttcagagtgt gaggttcgaa aacgattcat gatctggaca cgtaattgat tgaagctgcg
      421 attgatgtgt tggacaatat gaaagcggtc agttacgatc tccgcatttg gaaagaccgt
      481 tttaagcaac tgacaatagc tggcattcat gtccatcact aggtacttga cctttaaacg
      541 ggcctttcta ggaaagcgca ggaagtattg agttagtttg taaagtctgc gatcttcaag
      601 ggtcgtaaat agctgattgg ttgtcccatc aacacaaata aaactcatgg aaccagaagt
      661 ggcaacattg tgtacttttc tttgcaatct tgtgtacaaa actattgcaa aacacagcgc
      721 ataagaatcc ttacaaaaca gtagatgaag caacccaatt agatcttgtt atagttgtta
      781 atcagctctt aacgggttac gattcaaaat gggtcaacac cctatactta gataagtcac
      841 ttgaatatca gaacataatt caggcttttt cacgcacaaa tcgtcttaat ggtcctgaaa
      901 aaccgttcgg aaccattcgt tattatcgta aagcacatac gatggaacag aacattgaag
      961 aggctattga gttatactca ggcaaacaag caaaagggtt atttgttgaa aaattatata
     1021 ataacttaga aaagttgaac gatatattcg aagaaattaa gtccgtattt aatatttctg
     1081 gcatagaaaa cttcagtcat ttaccggagg ttccagggga aattaagcaa tttgtaaatc
     1141 tttataatca actaatccat tgttatgaat cagcgatgat acagggattc acatgggcaa
     1201 aatcgactta tgaaatccag gattatgaac ctataacagt agtaatcaca gaatatgaat
     1261 ttaatatctt ggcacaacgt tacagcgaga tagagagaga acctagagac ggaaatgata
     1321 gtatagcgta tgacattgat taccaattac ctgaaggtag tcgtagtcgt attaattatg
     1381 agtatttaaa cacaaacttc aaaaaataca tgaatataaa agaagaacgt gattcgaatt
     1441 taattcaatc attgttaaac gacttacatc gcacatttgc gcaattacca gtggagttac
     1501 agccatatgc tgagatgatt ctaaatgatg taaataatgg ggaattagtt atcaaagaag
     1561 gatgggaatt tactgattac ctcaatgaat atcagcttag tgaagaggac gattttatcc
     1621 aagatttagt ggattcaacc aatattaatg aggcattatt acgtgagatg ttggatttac
     1681 gcttaaccga ggtaaacatt aatgaatata gtcgatttga taaattaaaa tcaagtgtta
     1741 acgtaggtca tttcagtgga tatatcgaga aaaatttagg taaaatggta ataccaatca
     1801 aggtaaatat gctaattgac agattattgc gtgcattttt attagaagat gtattcgatg
     1861 ttacagagta cataaagaat tactttaact agagtacacc tacatcttat agtacataaa
     1921 aaaattcatc ttttttagtt taataattca ccaaaaaggt gagtaatgcc atttttgaaa
     1981 attgagcttg ttttatgtct acatctgtat ccgtatataa tccaaaggat tataaactca
     2041 gaagagtctt tattttttct gaatataact actgtatcaa aaacaatcga ttatgagaca
     2101 aaacaaaatg acctctttta tttaagaaag gaggtcattt tttgtatcat aaattgtatt
     2161 aaaatcaatg tatcactttt taatcaattt taagaccata aattgcgtac taaaagaaat
     2221 tctgcaattc aaaataaagc attttaagcc attttcaaat ttaagtgcac ccatctaccc
     2281 gtcaaatcac tttattttcc actccagtag tttcctaatt caactgtgtg caaaacgatt
     2341 tcttctaaac aaatcaagac aaacttataa accttcatcc cagcaccata attatttaaa
     2401 tcataggcat ttttcgaaat tagtatatgt actcaagttt cactgcagat tatttatatt
     2461 ttttagagaa ataaattttt cctattgaca aacacaaaga aagcggatac aatacaatta
     2521 tgtcacatga cgttatatga cgttatgtaa tatctttaca tttaatcagt tacttttatt
     2581 ttggataaaa ttaacatttt taaaatttta aggaggaaat gttgatggat gtagcaaaaa
     2641 cggttaacgc aattgtagaa aaaaatgatg gagagatttc tggaatttat ttggtggctt
     2701 gtggcggttc gctggtagat atgtatgtct cagattattt tcttaaagcc gaagcatcga
     2761 agtgtattac aggcttatat acagcgaacg aatttaacca tgtaacccca aagcaattag
     2821 atgataaatc tgttgtcatt ctatgttctc atggaggaaa tacagcagaa acggtaaaag
     2881 caggagaagt cgctcaagct agaggagctg tgactgttgg tctgactcat aataaaactg
     2941 cggatttatt aaaggtttct gatcatagtt tcctttacga atggggagat gatgcaaaaa
     3001 tagtcaataa tcctatggcc atcattcttg atttaactgt atctttggtc aatgttaccg
     3061 aaacatttga acattacggt aaattcagag aaggcatgaa ggttatcgat accgtaattg
     3121 aaaatggcat taagcaggtg caggatcgta ttaaagtgtt tgctgataag tacaaagatg
     3181 aaacaatgtt ttatatctta ggtagtggac catcatatgg acatgcttat ggtttttcaa
     3241 tttgctcttt gatggaaatg caatggcttg attcaacttc tgttcattct ggagaattct
     3301 tccatggacc ttttgaagta acagacaaag atacgaattt tattctcttg atgagcattg
     3361 gacgcactcg tgctttagat gaacgggcaa aacgattcct tgataaatat gcagaaagag
     3421 tagaaatcgt tgatgcaaag gaactaggat tggatatgat atcagatgaa gtttctgaat
     3481 tcttcaatcc cattttattc tacagtattc tttcagaata tcgttcagct ttagcagatg
     3541 cacgcaatca tgatttagat gttcgtcgct atatggggaa agtggagtac taggaggatt
     3601 aaaatgaagg tattaggctt aggtgataac gtcgtcgata aatatgaaaa tctgggaatt
     3661 atgtatcctg gaggaaattc attgaatttt gcagtttttg caaaaaaact gggacatgaa
     3721 agtagcttta tgggagtttt tggctcagat gaggaggcag ctcatgtttt atcagcaata
     3781 aaaaaaatag gactggacaa cagtcactct cgctttgaaa aaggcgagaa tggctgtgcc
     3841 agagtgaaga ttgatgaggg cgaccggatt ttccttggca gcaattcggg aggtgttact
     3901 cgtgaatacc cgattcagct tactgaagaa gacagagaat atttaaacca gtttgaattg
     3961 attcatatgg gattatatag ccatgtcaat catctattag aagagttaca aaatgtttct
     4021 ggaaagattt cttatgattt ttctgacgac tttacggaag aagaggttca gcgggcaatt
     4081 gataaagttg attttggctt cttttctata gaagactttt ccgatgaaga agtaaagcag
     4141 tttttgatga agcatttttg tgagcgaaat gatgtattga ttgcaacccg aggagaaaaa
     4201 acggctattg gttatgatgg agcaaagttt tatgaagtga accccgtgct agaagaacca
     4261 gttgatacaa tggcagcggg agattctttc ttaacagctt tcctacttta ttttctcgaa
     4321 ggggacgata tagtcaccgc gatgaaaaag gggaatgaat ttgctgggaa gtcttgtctg
     4381 gttgacggtt cgttcggctt tggtattcat tacgattgag cttgttttaa attcctgcat
     4441 ttgataacct aaagaaagaa atcccggtaa agtggaggtt aaaaaaatgc tggatacaaa
     4501 tgcacaatta ccattgtact tacaattaaa agaaatatta aaaaataaaa tcaatacagg
     4561 ggagtatccc gagaatacga aaattcccgc tgaatcagag ctgatagaaa gttatgaggt
     4621 cagccgaatc acagtgagaa aagcagtaga agaactggta gaagaagggt acctacttaa
     4681 aaaacaaggg aaaggaactt ttgtcaaccg gcataaagtt tttcgtaaaa ttgaatatgt
     4741 tatgggtttc agtgagagtt gtaaatctaa tggttttaca ccgactagca ttgttttgga
     4801 acgcaagatc attccagcaa ctgaagggat ggcaaaaaaa ctcgatatcg ctcaaggtga
     4861 tgatgtttta tatatccaga gaaagcgaat ggcggataac atccccatta tgttagaaaa
     4921 caattatttt tcttatgaaa gatatagttt cttaatggag gaagagctga ctgattcttt
     4981 gtatgaagta cttaaagtcc aaggtacctt agccatcaat cctggggaaa ctgcacttga
     5041 aattgtcaca gctgatgacc aaattgccaa aataatggaa gtagctgttg ggacgccctt
     5101 tttctttatg gatactttaa tcaacgatca aaacaacata ccaattcatg taggtaatca
     5161 atattacctg ggagaagtat atcgttttta cttatgattt cctgttttga tttcaaggag
     5221 tagattttat ttatgaagca aatattgcgg tcaaaaatga tttttgatgg agagcagcca
     5281 cctttcaaag gttatattgt aatcaatgaa gggatcattg aaaaggtgga aaacaactgg
     5341 aattacagtg atctattaaa tgaaaacacg gaattaattg cttatgatga tcaattcgtt
     5401 atgccagcaa ttcatgataa tcatgtattt ttcagtggtt atttggctat gaatgctggc
     5461 atagatttaa gcgatacatc ttcagctaac gaggctgtag agcgtattaa agctgtaatg
     5521 aaccataaaa aagcagatga accaatttat gctcatggct gggatgctgc cctgtggaaa
     5581 actgacccat cagaagagct attgaatgaa ataaactact ttggtccaat cacagcgatc
     5641 gacaaaaatc gcagccattg ttggatgaat gctattgcta agcagactta tggttttaca
     5701 gaaaaagaaa ccagtgctga aagtcgagta ttattaatta aggaaatgct agcaaacaaa
     5761 aagcttttag cagaggttta cgctgaattt gaagcattac tgctttcaaa aggtgttata
     5821 tcaatgaaag aaatcgtttt tgatgacgca gaatttcttt ctaatatacc tcagaggaaa
     5881 atacttagta acctatatgt gcaggcagtc caagaacctc tacagcatga acttctatat
     5941 gagtataagg aaaaagtttt ccctgaaaag gtccgctttg gtggagtgaa gatcatggta
     6001 gatggtgttg ttgcggatag aagtggagat atttacggtg tttatcagtc aggagtagct
     6061 tcacccgaga ttgactatga ggcaattaaa gcagaagttg ctgcattcaa tgaagtagag
     6121 attccttgct gtttgacaac ggaaggagat aaagcgggtt ataaagctgc gtcaattctt
     6181 gtcgaatttg gaaagcggtt acctgaaggc gtttttaatt cgattagtga tttggaaatg
     6241 gttactcaaa agacagcaga aaaaatgaac gaaggacaag tagtagcaga ggtatatcca
     6301 caaattctcg gcttgaatca aacgttagaa gaggcttaca tgtcaactgt tataaaaaa
//
LOCUS       DAFBSV010000117         6294 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.120, whole genome shotgun sequence.
ACCESSION   DAFBSV010000117 DAFBSV010000000
VERSION     DAFBSV010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.120"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            2..74
                     /locus_tag="LLB18_002577"
     tRNA            2..74
                     /locus_tag="LLB18_002577"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            78..150
                     /locus_tag="LLB18_002578"
     tRNA            78..150
                     /locus_tag="LLB18_002578"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Phe,seq:gaa)
     gene            155..225
                     /locus_tag="LLB18_002579"
     tRNA            155..225
                     /locus_tag="LLB18_002579"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:187..189,aa:Gly,seq:tcc)
     gene            238..311
                     /locus_tag="LLB18_002580"
     tRNA            238..311
                     /locus_tag="LLB18_002580"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:272..274,aa:Ile,seq:gat)
     gene            323..394
                     /locus_tag="LLB18_002581"
     tRNA            323..394
                     /locus_tag="LLB18_002581"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Glu,seq:ttc)
     regulatory      583..662
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            660..1853
                     /locus_tag="LLB18_002582"
     CDS             660..1853
                     /locus_tag="LLB18_002582"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBK5245546.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1983..3455
                     /locus_tag="LLB18_002583"
     CDS             1983..3455
                     /locus_tag="LLB18_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5245547.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3538..4326
                     /locus_tag="LLB18_002584"
     CDS             3538..4326
                     /locus_tag="LLB18_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBK5245548.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(4393..5061)
                     /locus_tag="LLB18_002585"
     CDS             complement(4393..5061)
                     /locus_tag="LLB18_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HBK5245549.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            5176..>6294
                     /locus_tag="LLB18_002586"
     CDS             5176..>6294
                     /locus_tag="LLB18_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5245550.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLA"
BASE COUNT         1825 a         1072 c         1412 g         1985 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgtttggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      121 gtgtcggcag ttcgattctg tcccgcgcca ttatgcgggt gtagtttagt ggtaaaacca
      181 cagccttcca agctgttgtc gcgagttcga ttctcgtcac ccgcttttag tttttatggg
      241 cctatagctc agctggttag agcgcacgcc tgataagcgt gaggtcgatg gttcgagtcc
      301 atttaggccc atttatttta ttggcccgtt ggtcaagcgg ttaagacacc gccctttcac
      361 ggcggtaaca cgggttcgaa tcccgtacgg gtcatggaag atactttttg agtatctttt
      421 tctttttatc tgaaagaatg attttaaaaa gcttagcaga gttatcttta tggatgattg
      481 tgctaagctt ttttggacag ttctaatgta aaatattttt atatttttta agcaaaaaaa
      541 tgaaaaaata cgagcagaaa actgttttat ctgctatact tggttcgttg caagttcccg
      601 aaaggatccg caggacggag atgccttgta accgaattta actaggggga atcattataa
      661 tggtagaaag acacttattt acatcagaat ctgtttctga aggacatcca gataaaattg
      721 ctgaccaaat cagtgatgca atcttggatg caattttaaa acaagatcca acagcacgag
      781 tagcgtgtga aacgtctgta acaactggtc ttgttttagt atttggagaa atatctacga
      841 cggcatatgt agatattcaa aaagtcgtac gggaaacaat aaaagaaatt ggttatacac
      901 gtgcaaaatt cggatttgat ggagatacag cagctgtatt ggttgcgatt gatgaacaat
      961 ctcctgatat tgctcaagga gttgatgaag cacttgagat ccgggatgaa gataaaaaag
     1021 acgtattaga tgagattggt gctggtgacc aaggtttaat gtttgggttt gctgtagatg
     1081 aaacaccaga attgatgcct ttaccaatcg ctttgagtca tcgtctggta cgacgcttgg
     1141 cagatttgcg taaatcaaat gaattaacgt atttacgtcc agatgcaaaa tctcaagtaa
     1201 cggttgaata tgatgatcaa ggacaaccgg aacgcgtaga tacaatcgtt atttcaacac
     1261 agcatgatga tgcagtagat aatgaaacaa ttcgtcatga tgtcatcgaa aaagtagtga
     1321 aggaagttat tccagctgaa ttattagatg atcaaacgaa atattatatc aatccgactg
     1381 gccgatttgt cattggtggt cctcaagggg atgccggatt aacaggaaga aaaatcattg
     1441 ttgatacgta tggcggttat gctcgtcatg gtggcggtgc tttttctggt aaagatgcga
     1501 caaaagttga ccgttctgcc agctatgctg cacgttatat tgctaaaaac attgttgcag
     1561 cagggcttgc tcgcaaagca gaagtacagc tagcttatgc gattggtgtt gctcaacctg
     1621 tttcgatctc aatcaatact ttcggtactg gaacggttcc ggaagaagaa ctgattgctg
     1681 cagtgagaga aaacttcgat cttcggccag caggaatcat cgagatgctt gatttgcgtc
     1741 gtccgattta caaacaaaca gctgcttacg gtcattttgg tcgtacagat gtagatttgc
     1801 cttgggaaca tacggacaaa gtagatgcgt tgaaagcaag tttagcaaaa taagttatat
     1861 tcagctggaa cgatcgccaa gtggtggttg ttccagcttt ttttatggca gttaacctct
     1921 tgaaaaagat agtaattatt tatctatttt tagatcctgt cataatgaaa gggaggaata
     1981 agatgaaaaa agaaacaaat gttactttgg tcacagtgag tattttcatt gcaacgttca
     2041 tgacggctat tgaaggtaca atcgtaacaa ccgctatgcc aacgattgtc ggttcattac
     2101 atggaatgga aatcatgaac tgggtatttt cgatttattt gctgacaaac gctatgctta
     2161 ctccgattta cggaaaactt gcggataaag tgggacggaa accaatcttt atttttggga
     2221 cattattgtt tattatcggt tcgttatttt gcggtttatc tcaaagcatg attgggttga
     2281 ttgctgctcg tgcgattcaa gggatgggtg ctggggcaat gatgccagta gctttgacga
     2341 tcatcggcga tctttattct attgaaaagc gagcaaaagt tttaggtttg aatagttcag
     2401 cctgggggat tgccagtgtt tttggaccgc ttgcgggagg attcatcgtt gaaacgatca
     2461 gctggcactg gatctttttt atcaatgtgc cgatcggaat tctattaatt attttgattt
     2521 ggctatattt aaatgaacca aaaatcatac atgagtctaa accaatggat atttttggta
     2581 gttttagttt gatggccatg cttgtctcat tgctgttagg gttccaatta ttaggagacg
     2641 aaggaatgag tccgcttgtt tctgctttgc tgctaggtag tatcgtaatg ttaggtattt
     2701 ttgtttttgc cgaaaaaaga gctaaagatc ctgtcatcat gatgcattta ttcaaaaatc
     2761 cactatttgt tgtggtcaac ttggctgcag cattggctag tggttttttg atgggaatcg
     2821 atgtttatat ccctatgtgg atgcaaggtg tattagggct gaatgcagca attggtgggc
     2881 tggtattagc accattatca ctagtctgga tggtcggttc tttccttgca agcaagtgga
     2941 tgactcaaat gaaaactcat tgggtcttga gaattggact actaatcgca gctattgggg
     3001 gcgcttggtt gtatcttatg cctttcagaa gtaactattt atggtttttt gctatatcaa
     3061 cggtcatcgg tataggctta ggtgtgacca tgactacctc gactgtcagt gcacaaaata
     3121 gtgtatctcg tgaccagctt ggtgtagcaa cttcttttaa tacgttagtt cgaacaattg
     3181 gtcaaacagt catggtttct atttttggtt tattgataaa tggggtaact aaacgagaac
     3241 ttgcagcagc aaatttaaca aatgatgcag atatcatgaa taaactggtg aatccacaaa
     3301 cggctaaata tattgatgcg gatattttgt taccattaag aaaaattctt tatgatgggt
     3361 tacattccgt ttatctagtt ggcttgttac tcgtgatcat tgctttggtc ttaacgcttt
     3421 tcgttcatga aaaaagtggt aaaataaaac agtagtttcg gttaagatat gtacgtagcc
     3481 gaatcattca aatttaaagt tattcaaaaa taacttctta ctaaggaagg cgaaaatatg
     3541 gcatttattc aagcaaatat ttattcgaat gtgttagaaa tggaagtcaa tctaaatgtg
     3601 atactaccgc aaacaacaaa aaaggtgatt ggcaccagtt cagagcaaga gacaacggat
     3661 atacctgttt tatatttact tcatggaatg ggtggcaatc atagtgtatg ggaaagacgt
     3721 acgtcgattg aacgttatgt agcaaactac ggattagctg tcatcatgcc atctactgat
     3781 cttggctggt acacagatac agtttatgac atgaagtatt ggacattcat tgcagaagag
     3841 ctacctgaga tttgtcatga attattcccg caattaacaa gaaaaagaga aaaaacatat
     3901 gccgctggat tatcgatggg cggatatggc gcgttaaaac taggccttgc aaaatcagaa
     3961 aatttcgcag cagtaatctc tctttcaggc gctgtttctg taggaaatcg aatggatgat
     4021 cttttgatgg ttcgtaaagc atctttttgg gaagggatct ttggaccatt ggatcaaatc
     4081 gaaggttcaa aaaatgatcc gcaatactta ttgaaagaac tagtaaaaag cggaaaacca
     4141 gttccaagat tttatatggc ttgtggggaa tctgattttc tttatcaggc aaatcaggaa
     4201 atggtatctg ctatgcagga acaaggcttg gcggtcacct ttgaacaagg acctggcgat
     4261 cataactgga tcttctggga ccaatggatt caacgtgcat tggcgtggct aatggaagaa
     4321 aaataaaaaa agagtcttaa aaagatagct cctatagaga tcacaaacat agtgatctct
     4381 ataggagctt ttttactgct cgttttctct tcttttattt tgttggcata agccttcaat
     4441 ataggtttgt gcactcgtta gaaagagtgc tttttcattc aattctgcat gggactgcat
     4501 actttcttta aatccctcta attgattttc aactacataa ttacgcataa atagaactgt
     4561 ttctttcaaa aattcatttc cgtccataat tttttgtcga agctgctgtt catgctgctg
     4621 atccattaac tgtccaatca ataaattgtg gagagaggca atggcctgat gactttgggt
     4681 gactgaaaat ccttcacgaa caagtaattg gatcatttgc tccaaatgtt ctaatcgact
     4741 cggaaaagcg ggcacagtat tgatttctaa ttctgcccca caagggaaac gtgtataaag
     4801 gtcatagtaa ttttccatat actgcagcaa ctgttcattc caaggcaaag ttggatctgg
     4861 aagcgctaat tcttcttcca ttgtttcagc cattttttgc aagagctgtt gtttgttttt
     4921 gaaataccaa tataaagcag gtgcttgaac atgaattctg tttgcgatgt ttcgcatgga
     4981 aagctgcgaa agagcttgtg tttcagccag gatatcaaag gcggcctgaa tgatgattgc
     5041 ttgagaaagc tttatttcca ttttatcaac ctcgtgtatt gcattatctt tttaaacatg
     5101 gtaaattgtt agtcggtcta attttacagt gttaaattag tcctgtcaat ttaaacaaag
     5161 gggtgtaatc aacgaatgaa attaatctta cgacatgcga aaaaatataa agtagctgtt
     5221 tttatttcct tgctgtccgt agcagtcatg gttgcagcag cattatggca acctaagtta
     5281 ctacagcaag tattggaagc tattattaca gaagataatg atgaaatgaa aacaattggt
     5341 atttacctga tcagtctggc tttgctagga ttagccgcag gtgtaacgaa cacgattttc
     5401 tctgcaaaag tagctcaagg cgtaagtgca gatatccgag aagaagcatt tcgaaagatc
     5461 cagacatttt catttggaaa tatcgaacag ttctctgctg gaaatcttgt tgttcgtcta
     5521 acaaatgata tcacgcaaat ccaaaattta gtgatgattt ctttgcaatc actttttcga
     5581 attccattct tatttattgg tgccttcatt ttagctatga tcacgatgcc gcaattatgg
     5641 tggatcatcg tagcgcttat cgttacggta tttctgatta cggcactttc atttacaagg
     5701 atgggcaagc acttcatgat cattcaaaaa ctgattgatc gtgtgaatag cattgcaaaa
     5761 gaaaacttac tagggattcg tgtagtgaaa tcttttgtac aagaagaaaa ccaattgaag
     5821 tcattcagca aagtaagtga ggacttaaca aaacacaaca tcatagtcgg tacattattt
     5881 tctgtgatga tcccgtcctt catgctggct gccaatttgg ctgtggttgg ggcgatcttt
     5941 tttgtgagcg atcttgttaa agatgatcct acgttaattg gtggaattgc ttcattcatg
     6001 aactacttga tgcagattat gatggcaatc attattggcg gaatgatgat gatgatgact
     6061 tcaagagcag ccgtatcgct gaagcggatt gcggaaattt tagatgctga accagatctt
     6121 acttatttag acgttccaga acaagagttg acgggttctg tcacttttga ccatgtttct
     6181 tttcgttatc ctggtgagga tacagatacg cttaaagata tcagcttttc tatcaaacct
     6241 ggagaaatgg ttggtatcgt cggggcgact ggtgccggga agtcaacact agca
//
LOCUS       DAFBSV010000118         6207 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.121, whole genome shotgun sequence.
ACCESSION   DAFBSV010000118 DAFBSV010000000
VERSION     DAFBSV010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6207
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.121"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            191..709
                     /locus_tag="LLB18_002587"
     CDS             191..709
                     /locus_tag="LLB18_002587"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBK5245551.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            837..1520
                     /locus_tag="LLB18_002588"
     CDS             837..1520
                     /locus_tag="LLB18_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBK5245552.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1829..1902
                     /locus_tag="LLB18_002589"
     tRNA            1829..1902
                     /locus_tag="LLB18_002589"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1863..1865,aa:Arg,seq:tct)
     gene            2061..2420
                     /locus_tag="LLB18_002590"
     CDS             2061..2420
                     /locus_tag="LLB18_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HBK5245553.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2543..4174
                     /locus_tag="LLB18_002591"
     CDS             2543..4174
                     /locus_tag="LLB18_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HBK5245554.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4236..4877)
                     /locus_tag="LLB18_002592"
     CDS             complement(4236..4877)
                     /locus_tag="LLB18_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBK5245555.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    5063..5139
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            5159..5467
                     /gene="rplU"
                     /locus_tag="LLB18_002593"
     CDS             5159..5467
                     /gene="rplU"
                     /locus_tag="LLB18_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBK5245556.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5494..5838
                     /locus_tag="LLB18_002594"
     CDS             5494..5838
                     /locus_tag="LLB18_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBK5245557.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5851..6144
                     /gene="rpmA"
                     /locus_tag="LLB18_002595"
     CDS             5851..6144
                     /gene="rpmA"
                     /locus_tag="LLB18_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBK5245558.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
BASE COUNT         1955 a         1023 c         1313 g         1916 t
ORIGIN      
        1 ttgtaatgtt agggtaaacg ttttttaaac taacgtcaat tatttataat aaaaaatgag
       61 ataaagatga ggaaatagaa ttagaaacat ataattatta aagggaaaca tttttacagc
      121 tataatttga aaaaaattta tcgttattat atgattaaga aggattgaat aaagaaagaa
      181 gttgaaaacg atacctgatt acaaaaaaat aacttttata agttctataa cgttgattat
      241 atttttaatt cttattcttc tcgtcgtctt ggttccccga atttttggtt tgactcctta
      301 tattattgag gacaaagaaa tgagtccata ttatgcacaa ggaaatctga tatatgtacg
      361 accgaaaaat acaaatgaga ttttagtcgg agatattatt acatattatg aaaattcagg
      421 aaaaaaaatc tcgacgcgtc gcgtaatagc cgttgaaaac aaccacgaag atttttatac
      481 aaaagctgat acaaagactt atattgagcc tggagtagta aaaaagagaa atattatcgg
      541 tagtcccatc tttcagattc catatattgg actagtcctt tcaaaaacgg catttgcatg
      601 gattcagggg ttattcttta cgattgcttt ttgcctaaca ggaatcacag catggaatac
      661 ctttgtagag ttgaaaaaga agcggagacg aacacagaaa tttttgtaag aatgttaaaa
      721 acataaatgt attccagaga tccaacgact cttctgaaca tgaaacacga gaaaacactc
      781 atgcagcttg tagatttagt cagttgttcg tataatgtgt gaagaggagg agtagtatgc
      841 gcaatgaaat gatgcatcgt cctgtagtca aagaagaact attggatttt atgcgtaccc
      901 agcaaaaaaa attaccgggt gagctaggca aactggaaga agaagctcat gtagcagaag
      961 taccagttat tccccatgaa acagttgtat ttttgaaatt tttacttgga cagcttcagc
     1021 ctgaacgaat cttggagatc ggagcagcta tcggtttttc atcaagtgtc atggccacga
     1081 caatcggaga aaacgctcat gttacgacaa ttgatcgttt cgatgtcatg atcgagaaag
     1141 ctaaaaaaaa ctatgaacgt ctaggactga cagataaagt gactttgctt gaaggtcaag
     1201 cagcagatat cttgccggag ttgtctggtc cgtatgactt tatttttatg gatagtgcaa
     1261 aatcaaaata tattgaattt ttacctgaat gcttacgttt gttaagaaaa ggtggcgttt
     1321 tgatggtaga tgacatcttc caaggaggaa cgatcttgct cccagatgaa gagattcccc
     1381 gtggcaaacg agctatccat cgtaaattaa atgaatttct tcgtgttgtg atggatcatc
     1441 ccgatttgac atcgacaatc ttgccattag gtgatggtgt gatcttaatg acaaaggaat
     1501 cagaaacaat cgagttgtga tacatgatta tggcagcctg tagataatcg attgaatcga
     1561 gggctcaatt cgaacttgat gtaaaagttt ctatatttgt aagtcaatta aaggatacag
     1621 gaaatctaaa taaacaggag tagcatgaag tcaatgtagc tcctgttttc aattgataac
     1681 cttagaacag ctgaaggaga atgtctcgtt ttaaaagatt gatttagtag ttgggccaaa
     1741 ataattcatt atttgctaat taaataacta tttcgtattg acagaagcaa tttaattatc
     1801 tataattatt gatgttccgc tgattcttgt catagtagct cagctggata gagcatccgc
     1861 cttctaagcg gacggtcggg ggttcgaatc cctcctgtga cgctaaaaaa ccgttagaaa
     1921 ctgaggtttc taacggtttt tctttgtttt ttgtgccaat attgtttgtt ttcaaaggca
     1981 aataaaataa aaaaacatcc ttatcgagta caattataag gagcaaaaaa ataaaactca
     2041 tcagaaaaga ggaagaagat atgacgatac tatctagaat tttagtgact ctagttgcaa
     2101 ttgaattttt ttatatcatg tatatcgaaa cggtgagaac tgattctgac acgacaagta
     2161 gggtttttaa aatgagtaaa gaagagttaa gcagaaaatc tgttcaaaca ttgtttaaga
     2221 accaaggagt gtacaatgga ctattaggag tgggactact ttatggagct tatctttctt
     2281 ccgcatctaa agaaatcaca agtatgctat taatatctat tttttttgtt gcattatatg
     2341 gcagtttgac tagcgatcgt tggattttac tcaaacaagg tgggctagct ctgttggcat
     2401 tgctttctat tttcttataa atatagaaaa aataagaatt tatctaacag gaaactttgt
     2461 gaaaaatatt actttatctc atgaaatatg atattctaat gaatggtatt ttagaaaatt
     2521 tcatgaaaaa ggagttagat aggtgttcaa aaattatgtt tcctcactaa aaaaagaatt
     2581 ttcaggttat gatctttcaa gatttcagaa agatcttttg gctgggatca cagtagctgc
     2641 tgtagcattg cctttagcct tggcttttgg ggtatcaagc ggagctgatg cggccgcagg
     2701 tttgattacg gctatcattg ccggtatcgt tattggcggt ttatcaggcg gtttttatca
     2761 aatatcaggt ccgacaggtg cgatggcagc tatcttgatg tctattgcgg caacaaaggg
     2821 aatgcaaggt gtattgcttg ctactttttt agcgggtcta tttttacttg cagcaggact
     2881 tttccgatta ggaacactga cttcttttat cccagcaccc gtaattacgg ggtttacttc
     2941 aggtattgct atcattattg cattaggtca gatcgataat ttatttggtg ttcactcgga
     3001 aggtacaaac gttattgaaa aactaagtag ttatcaaacg ataggatttc cgataaacac
     3061 agcctctttg atcatgggag ggctagtcat tttagggatg tttatctatc caaaaaaatg
     3121 ggcgaaacga atgcctagtt cgctgctggc tatcattttg gcaacagcag ttatgctatt
     3181 gttccattta ccagtagcaa ctgtgggtaa gattccacaa acattgatca gtagtaatcg
     3241 tttgaatatg ggagatttta gcttttctgc cttgcaacaa gtggcagttc cagctattag
     3301 cattgcttta ttaggaatga ttgaaagctt gctatgtggt gcttcggctg gccgaatggc
     3361 aaataagccc ttagatagca atcaagaatt aatggcgcaa ggaattggaa atctgttgct
     3421 tcctttcttt ggcgggattc ctgctactgc ggccatcgcc cgtacaagcg tggccatcaa
     3481 atctggtgca caaactagat tagctggtat gatacatgca gttgtcttac tgctctccat
     3541 gcttgttttt gcgccagtga tgtcacagat tccaatgcca gcacttgcag gtgttttgat
     3601 tgtgacggct tggcgtatga atgaatggga aacgatcaag gagctattta ctaataaata
     3661 ttggtcagca gttctattgt ttatccttac gatgatttgt acagttatct ttgatttaag
     3721 tattgctatc gtgatcgggg tgatcggcgg ctgtgtattt tttgttgtca aaagcgctgc
     3781 tatcacgatt tcattagaaa cgatcgattg gcaaagaatg gggctgccag aaacggaaaa
     3841 gctgaataac tggacagtag tgtatattag tggtccactg ttttttatgt cttcagaaaa
     3901 actcaaaaat aaattggaag aactaaatca tcacgatggt gtcattttct ccatgcgagg
     3961 cgtaccaagt attgatttga cggcacgtgc agtttttgat gaatttcaag aaaaagcaga
     4021 gcaaagagga caaacgatta tctatacttc cttgcagcca gaagtagaaa aacaactttc
     4081 tcacttgtgg gaacatacat tcacgcatca acatcaaaca gttgctcatg cgttgacagc
     4141 tttacatgcg aaatatactg caattagcca ttaaaacaat gaaaaagaac agacaagact
     4201 gtaaactgaa gattttatgg tcttgtctgt tctttttaat attgctgtaa aagtgaagct
     4261 agtacttgcc agtcttgatg gataacaggt acaagggagc gattgtagaa aatagctgct
     4321 ggatgaaaaa gtggaagaat tcgatagttt ttttctgacc attcgtaggc atccttttgt
     4381 tctgttaatt gtaagacagg ccctgtatag agttgaccat gatttttggt aaccgtatat
     4441 tctttgccaa gtaaacgttg aagaccaatg tttccaagtg tcgcaattaa ttttggctgg
     4501 accttcatca gttcgtaatc caatattggt gcatgcgcaa atacttcgga acgagtaggt
     4561 gtccgatttg gataaacagt ttctgactgt tgtgtccgtt tattgatccg atgagtcacg
     4621 cgatacgggc ggctccttac agcactggtg atatacacct cttctcgtgt taagccagtt
     4681 gaagaaagtg cctgcatcaa ttcttttcca gcttgaccgc taaaaggaac atgcgtatca
     4741 atctctgttt tccctggggc ttctcccacg agcatcagtt taggatgaag aggtccttgc
     4801 ccagcgataa atccttctac aggacggccg ttcattctta aagaagcttc ttgtatcagt
     4861 tcttttgggt attccattta tgctcctcct ttttctttta ttataagaat aaaagaaaca
     4921 caatgcgact attttatttg gtagaactgt gaggatagaa aagcagaagt attgcttgaa
     4981 tttttgtttt actttttgat tttaaattta gttgactaac ggttgctgtt ctggtaagct
     5041 agtactgttg taattgtgga ctccacagct acaaccgctc agaacaagta ataagcacag
     5101 catatgctgt cacttcggat ggcgagtcta agtatatcag aaggaggtgc tttatagcat
     5161 gtacgcaatt attaaaactg gtggtaaaca agtaaaagtt gaagtgggac aagcaatcta
     5221 tgttgaaaaa cttgacgttg aagcaggaga aaaagttgtt tttgacgaag ttatcttagt
     5281 aggcggagaa tctacaaaag taggcgctcc aactgttgca ggtgcaactg ttgaaggtac
     5341 tgttgaaaaa cacggcaaac aaaagaaagt cgttactttc aaatacaaac ctaaaaaaca
     5401 ttcacaccgt aaacaaggtc atcgtcaacc atatacaaaa gtggttatcg acgcgatcaa
     5461 cgcttaatag cgtttgagaa agaaggccta tatatgatca aaggaacatt taagcgaaat
     5521 gacgcaggtc agatcgtttc attcactttg accgggcatg ctgatgctgg tccttatgga
     5581 agtgatatcg tttgtgcggg tgtttctgcg ttagcgatca gcactgtcaa cgggattgcc
     5641 tcattagccg gttttgagcc gattgttgaa atgaatgaag aagaaggcgg ttatctttat
     5701 accgaagtca cttcaggaat gacacaagaa caaaacaata ttgctgagat tctattagaa
     5761 aatcttttat taggattaca atcgatagaa gctgaaaact cagaatatat ccaaattaaa
     5821 acaattaatg ataaatagga ggtgcagacc atgttgttat ctatgaatct acaattattt
     5881 gcccacaaaa aaggtggcgg ttctacatct aacggccgtg actcagaatc aaaacgtcta
     5941 ggtgctaaac gtgctgatgg acaaacagtt acaggtggat caattcttta ccgtcaacgc
     6001 ggtacaaaaa tctatccagg tgtaaacgtg ggtatcggtg gagacgacac tttatttgca
     6061 aaagttgatg gcgtagtacg tttcgaacgt aaaggccgta acaaaaaaca agtgtctgtt
     6121 tatccagtag ctcaagaagc ttaattgaat cttatgatta aagaggttgt gacaagactt
     6181 ttgtcacagc cttttttgtt tataaaa
//
LOCUS       DAFBSV010000119         5903 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.123, whole genome shotgun sequence.
ACCESSION   DAFBSV010000119 DAFBSV010000000
VERSION     DAFBSV010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5903
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.123"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            113..778
                     /locus_tag="LLB18_002596"
                     /pseudo
     CDS             113..778
                     /locus_tag="LLB18_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            814..1059
                     /locus_tag="LLB18_002597"
     CDS             814..1059
                     /locus_tag="LLB18_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBK5245559.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            1162..2031
                     /locus_tag="LLB18_002598"
     CDS             1162..2031
                     /locus_tag="LLB18_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBK5245560.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            2012..2746
                     /locus_tag="LLB18_002599"
     CDS             2012..2746
                     /locus_tag="LLB18_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBK5245561.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            2779..3687
                     /locus_tag="LLB18_002600"
     CDS             2779..3687
                     /locus_tag="LLB18_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HBK5245562.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            3684..4226
                     /gene="sat4"
                     /locus_tag="LLB18_002601"
     CDS             3684..4226
                     /gene="sat4"
                     /locus_tag="LLB18_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HBK5245563.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            4319..5113
                     /locus_tag="LLB18_002602"
                     /note="aph(3')-IIIa"
     CDS             4319..5113
                     /locus_tag="LLB18_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HBK5245564.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            5389..>5903
                     /locus_tag="LLB18_002603"
     CDS             5389..>5903
                     /locus_tag="LLB18_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBK5245565.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMI"
BASE COUNT         2025 a          881 c         1300 g         1697 t
ORIGIN      
        1 catttagata gtagtggaaa gacctctatt tatcttttga aagtgaatac aaaaataaag
       61 cacactctgc tataatatag gtgattaatc catttgagag aggtgcttta tcatgtatca
      121 aaattatacc ataaaccaac tttgtttgcc tatagatctt gaaattaaat tagaagaaaa
      181 tgattttgct catgccattg tgcagtttgt tgactctatt cccgatgaag tctttcttcc
      241 ttattatcaa tctatgggta gaccccaata tcatcctcgt atgctacttt ccattattct
      301 ttgtgcctat attcaagggg tttattcggg ccgccaaata caaaatatgc tgatagatag
      361 tattcggatg cgctacttat ctcaagagca attccctaac tttcgtacta ttaatcgttt
      421 tcgcgttcat ccgattatga acgatattct agatcattca tttgttcaat ttcgtgagct
      481 actggttcaa agtggcttaa tcagtggcag tgctctatac attgatggta caaaaattga
      541 agcggatgcg aataaatact ctttcgtttg gaaaaaaagt attttaaagt ataaggatag
      601 ccttgatcaa aaagcccttg aaaactacca acaaatggtg gaaacaaaaa tcttacctga
      661 gttaatagat gatttaaagg atgaactttc tatagaagag attgaaagga ttcgtcaatc
      721 tttggaagaa aaggaaaatc aattaattga agcgattgac caaaccgaaa cagtagaagg
      781 gggctgaccc attattaata aggagtggac aacatgattg atgtaaatga gctattggaa
      841 gaagctatta gagaaactga aaatctaaat gatggcgaag tttttcttgt taaagattta
      901 ttcaagggat atgtggggaa taggataccc agaaaggatc gacttctgct tggaacgtta
      961 tttttaaacc atgttagcaa aatgaatggt aatttaaagg ctattgaaaa gacttcatct
     1021 aatcagcaga ggtataaaaa gacaattgat aagttttaac tatcttttgt gaaattaaaa
     1081 aaattataaa tatgttgagt agaagcaaaa gatttggctt ggaattttta cagcagtgaa
     1141 tcgataaaag gagcatgctt gatggtagat aatattatta aatcagtagc agagaaatta
     1201 tcctctctgt cttatataga aggtattgtt ttaggtggtt cacgtgcaag gggcacccat
     1261 acagaggatt cggatataga tatcggcatc tattacaatt cagaatcatt tgacataaat
     1321 actattaatc aattcgctac aaagctggat gatgagcata gaaataacct tgttgtacct
     1381 cccggagcat ggggtgattg gattaatggc ggcggatggt tagtcataaa cgggtatcat
     1441 gtggatttaa ttttacgtga tattaaacgt gtggaacaaa taatgaaaga tacagagcac
     1501 ggaattgtta ctgccaatta tcagactggg catccccatg gttatattag tgcaatgtat
     1561 cgaggagaat tagcgattag caaaatacta tatgctaaga atgaaagctt atgcgaatta
     1621 aaaaaacagg cagaaactta tcccaatgct ttgcagaaaa gtttagttaa cttttttatg
     1681 tttgaagcag ggttctcttt aatgtttgta aaagcaaatt cgggaacaga cgataaatat
     1741 tatattgcgg gtcatgtttt tcgtatagtt tcatgtttaa atcaagtgtt atttgcatgt
     1801 aataatgctt attgtatcaa cgaaaagaaa gctataaaac tgcttgaaac ttttgaacat
     1861 aaacctgaaa aatataccga gaaggtaaat catatttttg aagtactcgg tatctcactt
     1921 tttgaatgct acgacatgac cgagaagctt tataatgaag tgaatgaaat tgtatcggag
     1981 ataaataact ttttaaacga ggagagttca gatgaaagaa aacaaatatg atgataatat
     2041 attttttcaa aaatacagtc aaatgagtcg ctcgcagaaa ggactggctg gtgcgggaga
     2101 atgggagact ttgaaaaaga tgctacctga ttttaagggt aagcgtgtgc ttgatttagg
     2161 atgcggctat ggatggcact gtatatatgc gatggaaaac ggtgcttcct ctgtagtagg
     2221 tgttgatatt tctcataaaa tgctcgaagt agcaaaagga aaaacccatt ttccacagat
     2281 tgaatatgaa tgctgtgcca tagaagatgt ggatttccca gaggagagct ttgatgtaat
     2341 actaagttcg cttgcgtttc attatgtagc agactatgag aatttaataa aaaagatata
     2401 taggatgctg aaggctggtg gcaatttagt ttttacagtt gaacatcctg tttttactgc
     2461 tcatggaaca caagactggt attataacga aaaaggagaa atactgcatt tcccggtgga
     2521 caattattat tatgagggca aacggacagc tatgtttttg gaagaaaagg ttacaaaata
     2581 tcatagaaca ctgaccacat atctaaatac actgctttca aatagtttta taataaatca
     2641 gattgtggag ccacagccgc cagagaacat gatggatatt ccggggatgg cggatgaaat
     2701 gcgacgccca atgatgctga ttgtatcggc aaaaaagaag atgtaataat atagaaaaaa
     2761 taaacgagga gtatgtaaat gagatcagaa aaagaaatga tggatttagt actttcttta
     2821 gcagaacagg atgaacgtat tcgaattgtg acccttgagg ggtcacgcgc aaatattaat
     2881 atacctaaag atgaatttca ggattatgat attacatatt ttgtaagtga tatagaaccg
     2941 tttatatcta atgatgactg gcttaatcaa tttgggaata taataatgat gcaaaagccg
     3001 gaggatatgg aattattccc acctgaagaa aagggatttt cctatcttat gctatttgat
     3061 gattacaata aaattgatct taccttattg cccttggaag agttagataa ttacctaaag
     3121 ggcgataaat taataaaggt tctaattgat aaagattgta gaattaaaag ggacatagtt
     3181 ccgactgata tagattatca tgtaagaaag ccaagcgcaa gggagtatga tgattgctgc
     3241 aatgaatttt ggaatgtaac accttatgtt attaaaggat tgtgccgtaa ggaaatttta
     3301 tttgctattg atcattttaa tcagattgtt cgccatgagc tgctgagaat gatatcatgg
     3361 aaggtcggca tcgaaacagg ctttaaatta agtgtaggca agaactataa gtttattgaa
     3421 aggtatatat ccgaggattt gtgggagaaa cttttgtcca cctaccggat ggattcctat
     3481 gaaaacatat gggaagcatt atttctatgc catcaattgt tcagggcggt atccggtgag
     3541 gtggcggaaa ggcttcatta tgcctatccg gagtatgata ggaatataac aaaatatacc
     3601 agggacatgt ataaaaaata cactggtaaa accggctgcc tggatagcac atatgccgct
     3661 gatatagaag agaggcggga acagtgatta cagaaatgaa agcagggcac ctgaaagata
     3721 tcgataaacc cagcgaacca tttgaggtga taggtaagat tataccgagg tatgaaaacg
     3781 agaattggac ctttacagaa ttactctatg aagcgccata tttaaaaagc taccaagacg
     3841 aagaggatga agaggatgag gaggcagatt gccttgaata tattgacaat actgataaga
     3901 taatatatct ttactaccaa gacgataaat gcgtcggaaa agttaaactg cgaaaaaatt
     3961 ggaaccggta cgcttatata gaagatatcg ccgtatgtaa ggatttcagg gggcaaggca
     4021 taggcagcgc gcttatcaat atatctatag aatgggcaaa gcataaaaac ttgcatggac
     4081 taatgcttga aacccaggac aataacctta tagcttgtaa attctatcat aattgtggtt
     4141 tcaaaatcgg ctccgtcgat actatgttat acgccaactt tgaaaacaac tttgaaaaag
     4201 ctgttttctg gtatttaagg ttttagaatg caaggaacag tgaattggag ttcgtcttgt
     4261 tataattagc ttcttggggt atctttaaat actgtagaaa agaggaagga aataataaat
     4321 ggctaaaatg agaatatcac cggaattgaa aaaactgatc gaaaaatacc gctgcgtaaa
     4381 agatacggaa ggaatgtctc ctgctaaggt atataagctg gtgggagaaa atgaaaacct
     4441 atatttaaaa atgacggaca gccggtataa agggaccacc tatgatgtgg aacgggaaaa
     4501 ggacatgatg ctatggctgg aaggaaagct gcctgttcca aaggtcctgc actttgaacg
     4561 gcatgatggc tggagcaatc tgctcatgag tgaggccgat ggcgtccttt gctcggaaga
     4621 gtatgaagat gaacaaagcc ctgaaaagat tatcgagctg tatgcggagt gcatcaggct
     4681 ctttcactcc atcgacatat cggattgtcc ctatacgaat agcttagaca gccgcttagc
     4741 cgaattggat tacttactga ataacgatct ggccgatgtg gattgcgaaa actgggaaga
     4801 agacactcca tttaaagatc cgcgcgagct gtatgatttt ttaaagacgg aaaagcccga
     4861 agaggaactt gtcttttccc acggcgacct gggagacagc aacatctttg tgaaagatgg
     4921 caaagtaagt ggctttattg atcttgggag aagcggcagg gcggacaagt ggtatgacat
     4981 tgccttctgc gtccggtcga tcagggagga tatcggggaa gaacagtatg tcgagctatt
     5041 ttttgactta ctggggatca agcctgattg ggagaaaata aaatattata ttttactgga
     5101 tgaattgttt tagtacctag atttagatgt ctaaaaagct ttaactacaa gctttttaga
     5161 catctaatct tttctgaagt acatccgcaa ctgtccatac tctgatgttt tatatctttt
     5221 ctaaaagttc gctagataga gttctatatt agagatgtaa agagttttgg tgaagaggtt
     5281 tgtgagtatg gcttttataa ccagggtgca atgagaagca ctaacagcag ctagcttaag
     5341 aacgcatagg atatactttt tatggaagtc acagaggagg aataaaattt gaacaggatt
     5401 aacagagtaa cctctattct tattcagctg caatcaaaaa aaataattcc tgccaaagaa
     5461 attgcacagc gatttaatat aagcttaagg acagtttaca gagatatccg gacacttgaa
     5521 gaagccggaa taccaattgg atctgaggcc ggaaaaggat attttcttgt agagggcttc
     5581 ctacttccgc cggtaatgtt tacagcggcg gaagtgggtg cattgattac agcagggaaa
     5641 tttttaaatt gccatggaga tgaatcattt ataaaggatt ttgattcagc tatgtataaa
     5701 atcaaatcta ttttgaagca tggtgaaaaa aactatgcac aggagttgga gaacagtatt
     5761 aacgtgtaca gcacatctgg acagaaaaat acattggcgg ataacgttat tgcagcaatt
     5821 cagactgcaa tctgcaataa aagggtaata tcaattcaat atcctgcatc aggagggcaa
     5881 gaaccggaaa gcagaatgat aga
//
LOCUS       DAFBSV010000120         5877 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.125, whole genome shotgun sequence.
ACCESSION   DAFBSV010000120 DAFBSV010000000
VERSION     DAFBSV010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5877
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.125"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            641..1375
                     /locus_tag="LLB18_002604"
     CDS             641..1375
                     /locus_tag="LLB18_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK5245566.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1391..2560
                     /locus_tag="LLB18_002605"
     CDS             1391..2560
                     /locus_tag="LLB18_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBK5245567.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2576..3571
                     /gene="lacD"
                     /locus_tag="LLB18_002606"
     CDS             2576..3571
                     /gene="lacD"
                     /locus_tag="LLB18_002606"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBK5245568.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYAEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3650..4576
                     /locus_tag="LLB18_002607"
     CDS             3650..4576
                     /locus_tag="LLB18_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HBK5245569.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4595..5845
                     /locus_tag="LLB18_002608"
     CDS             4595..5845
                     /locus_tag="LLB18_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK5245570.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         1967 a          956 c         1203 g         1751 t
ORIGIN      
        1 gtttgaaaaa tgctatttcg aggtagaagg atattatata agcacggttg actaaacgaa
       61 gtgataataa aaaaagttat tcaagaataa gaaaaattat gatacgaatt cagataaact
      121 ggagaataca gagaccttta aaagggataa gaaacaacat aaattcctct taagagagaa
      181 cgaaaggaca aagccagcaa cttgatacac gagctagtat tagaggaatt tattctcata
      241 gactcccttt tgaatacgtt tcaactttaa ttttcatgtt cataaatgat ttgaaaccaa
      301 agcaaatgcg ttgcactttt cctccgtctt ccgaaaatcg ttcaattcac tggtaagtag
      361 tcatttgata gtttgaggca aattgttgat tgatgaaggg taggagctaa aaaaagatac
      421 cagttgaaga gagaaaaaga aaaaaataga gggtgttctt gaatgaaaaa agttggaaaa
      481 ttatttttca tttcctttta ttcctattaa agtcagtgat gtcaatcata ttaacaagac
      541 taaaaatgaa aataaaaaaa agattgttct tagtattgac tcataaaaaa taccactact
      601 atacttacat tgtggttata gccagttagg agagacatcg atgcaaaata cctttcaatc
      661 aaaatcactt tattatcagc tggtagaaat attgaaacaa cgaatcgaaa acagtatggt
      721 cgctcatgac aagctgccat cagaaagaga gttgaccagt ttttatggcg ttagtcgcac
      781 gacggtgcga ctagcattgc aagaactgga aaaaatgggc tacatttatc gacaacatgg
      841 aaaaggaacc tttgtttcgg aattaaggac aaatgcgact gatctagctg gcgcatatag
      901 ttttaccgaa caaatgcggg caatgggcaa acatcctgaa accaagatat tggccttcaa
      961 gaagattgaa gcaactaaat atttagcgag tcatctgaat gttcaactag gtgagccttt
     1021 atttcaatta gaccgattgc gcttagctga tgatttgcca atgatgatcg agaaatccta
     1081 tttgccagtg aagctattta tgtccctttc tcaagaaatt ctatttctga aacctttata
     1141 taatttgttt tcagagaatt tcaatcaaat cgtacggttg gctgacgagg aattttatgc
     1201 cagcattgtc cagaaagaag atagtgagtt gctaaatatt ccagaaggat caccagtgct
     1261 ccatttagtt cgctcaacct ataatctcga gaacgaagtg attgaattta cattaagtgt
     1321 agcgcgggct gataaatttc attataagat caggcatctg cgttccacta actgaattgg
     1381 aggaaagaaa atgtttatgt tctcaaaaga agaactacga aagctaggag cagaaaatac
     1441 tacccgagaa attcgacaac aaccggaact gtggcatgag acgtttgacc gttatcaaga
     1501 aacagttgca gatttagatc gtttgtttac ggatgcgaaa caacatgctg gagagcgacc
     1561 aatccgagtc atttttacag gggccggaac ctcgcaatat gtgggagata cactaattcc
     1621 gtttcttact agtcaaggaa atacgaacca gtttattttt caaagtattg gttcgaccga
     1681 tatcgttgct acgccaaaag aatacctgat tcctgatgag acaacgatct tggtctcatt
     1741 tgcccgtagt ggaaatagtc cagaaagtct agccgcagtt aagatggcca atcagctggt
     1801 caacaagatc tatcatatcg tgatcacctg tgcaccagac ggattattgg ctacacaaat
     1861 gcctacaaaa aaagaaaatc tagttttact aatgccaaac aaagccaatg acgctggttt
     1921 tgctatgaca agcagtttca gctgtatgac gctgactgcg ctacttattt ttgatcaagc
     1981 aagcaatcag caaaaagaaa gatatgttca tcaattaagc cgactaggag aagaagtcat
     2041 ccaacgagaa tcagagatcc aagggtatct ggcatcagac tttcatcgca tcatttactt
     2101 aggttcggga agcttaggcg gattgactag agaagcgcaa ttaaaagttc tcgagttaac
     2161 tgctggaaaa atcgcaaccg tatttgatac atctttagga ttcagacatg gtcccaaatc
     2221 ttttgtcaat gagcaaacat tggttttcct gtttgtcagc aatgactcat atacgcagaa
     2281 atacgatgta gacatgctgg aagaaatcaa aaatgacggt attgcccaac gcgttgttgg
     2341 aattggtcaa aagggttcat tgtttagtgg tgattccttt gaattagttg cagattcgtt
     2401 actgccggat ggctatcttg ctttagcaga tatcatggta gcccaaacga tcgcattact
     2461 ttgttcggtg aaggttggta atacaccaga tacaccatcg ccaagtggaa cagtcaatcg
     2521 tgtggtcaaa ggcgtaacga tttatccata tgaaaaatag gaaagagtgt gaagcatgtt
     2581 agaatggtcg gaaaataaaa gacaagcaat ggaacgtcta tcgacgccag aaggcattat
     2641 taccgctttg gcgatcgatc agcgaggcgc gctgaagaaa atgatgtcgg ctttagggat
     2701 ggaagcgaca aaggaaaaaa ttgagcagtt taaaacacta atttcccaag aattgactcc
     2761 ttatgcctca gcaattttat tggatcctga atacggactg cctgctgcac agaagcgtgc
     2821 agcagcgagc ggtctgctgt tggcatatga aaaaactggt tatgatcaaa ccgtacccgg
     2881 ccgcttgccg gatctgctgt cggactgttc agttctgcga ttgaaagagt taggtgcgga
     2941 tgcggtgaaa tttttactgt attacgatta tgcagaagca gaggaaatca atcggcaaaa
     3001 gcaagttttt gttgaacgaa ttggaagcga atgcatggct gaaggactgc cattttattt
     3061 agagttattg tcatatgatg ctaaaaatgt agatacgaaa tcgctttcct atgccaaagc
     3121 aaaaccgcgc aaagtgatcg aaatgatgaa agaattctcg aaaacccagt ataaagtaga
     3181 tgtcttaaag gttgaagtac cagtaaacat gtcatttgtt gaaggaaatg caacagggga
     3241 gatcgcctat acacgtcaag aagctgccgc ttattttaaa gaacaaagcg atgcaacaga
     3301 tttgccgtat atcttcttaa gtgctggggt atcagcggca ttattcatgg agacattgcg
     3361 ttttgccaaa catgctgggg cacgattcaa cggtgtactc tgtggcagag caacttggaa
     3421 agatgcagtc gctcctttcg ttgaaaaagg agaagcggca actttagaat ggctgacaga
     3481 acaagggaca caaaacattc gtcaattgaa tgaagtgata agagaaactg ccatcccatg
     3541 gtatgagaaa gtaagtgaaa gcacttgtta atgtttctaa tatattagta gtgataagag
     3601 atatgtgtga ttataattta tcattattga aactgggagg atattttata tgaataaaag
     3661 attgttagat tattcagctt cagatttttt gaaagctaag ccgatggaat taaagcaggc
     3721 aattttggct tctgaaggta gaacaattat ggcagaaaat gtgccaagta gctgtcctta
     3781 catgggaaaa tcagtgacaa atgcagaatt ggagagagct gctggagctg atttaatttt
     3841 gtttaatgca ctagatcttt ttaatcctca aatttcaggt gtacctttaa ctctaaaaga
     3901 gaatccaata atctggatta aaaaagcttt aggaagagct attggtgtaa atttagaacc
     3961 tgtagacaaa gaagttttga tgagtgaaaa tcgaactgaa atttcaagtg gtagaatcgt
     4021 ttctcctgag actttaaaaa aggcaaatga attaggcttt aattttattt gtttaactgg
     4081 aaatccagga acaggagtat ctaatagaac tattgagaaa gcaataacat tatccaaatc
     4141 aatttttaat ggattaatta tcgctggaaa aatgcatggt gctggtgttg atgaaccaat
     4201 tatgaactta gatatagcaa aaagatttat taaaacaggt gtagatattt tattagttcc
     4261 tgctccatac actgttccgt atttcatgga aagtgatttg cgaggaatcg ttgattatat
     4321 aaaagatttt aatagaaata aatctattga ggaaaaagtt ctagtactaa cggctaatgg
     4381 aacaagccaa gactcttctg accaagaaac tattaaaaaa attgcattag catcaaaagc
     4441 atgtggagct gatattcaac acatagggga ttctttaaat ggtatttgtc ttccagaaaa
     4501 tatttttgct ttgggtcaag caattcgggg atatcgtcat caaattatta tgttaggaaa
     4561 atctaattat cgttaattaa ggaggaaatg aaagatgatc gacaaagttc aaaaaatagc
     4621 tgcaaaaatt agtaatcaaa gacatctact agctttaaga gacagcatgg ctgcagttat
     4681 gccattaatc attattggtt ccttttttat gttattagca aatttcccga tagaaggatt
     4741 tacaaaatgg ttatctgaaa ttggagtaca atcctttttg aacaaagcat cagattcaac
     4801 atttggtatt attggattag ctgttaccta ctctttggga cacaatctag caaagactta
     4861 tggtgtagac tcattatcag caggattatt atctttgagt ggatatgttt tacttacacc
     4921 tttattggat gcagatggtt ctataggatt tccaacaaaa tactttggta cctcgggtct
     4981 ttttgttggt attattgtag cacttgtatc tacagaaatt ttccggtggt ttgtacttaa
     5041 aaatattaca attaaaatgc cggcaagcgt tccaccaaat gtaagccgag ctttcgttgc
     5101 tattattcct ggcttttttg tcgttctact atggtttatt gttgttgtaa tttgttataa
     5161 acttggaatt gaaaatgttc atgctcttat tgcagataca ctcgcaaaac cactatcttt
     5221 actgacgaaa actttaccag gaattatatt ggttatactt attcaatgtt tcttttggat
     5281 gtttggtatt catggtgcac aggtaacggg gccaataatt gaaccgttat tattgcaaaa
     5341 ctctgatgta aatagaattg cttatcaagc tggaaaagaa cttcctaaca ttataactta
     5401 tgaattctta tataactttg ttttttctgg tggtgcaggt tgtttatttg cacttgccat
     5461 tttaacattt ttcttttcaa agagtcagga aaataaaact ttaggtaagt tatcaatcgc
     5521 tccagtaagt tttcaagtag cagagcccct tctatttggg tttccaacta tattaaatat
     5581 aaaaatgtta attccatttg taactgcacc agtagtaaca acattaatta cttatttttc
     5641 aatgagtatg ggattagttg caaaacctgt aggagcaaca atcccatgga caactccacc
     5701 gataattgcc ggatttttag cttctggtgg acgaataagt ggtgcagtga ttcaagtaat
     5761 aacaattgca ataaatgttt tgatatacta tccattcttt aaattagatg ataatgccaa
     5821 gctaaaaagc gaaaaaaatg attagaacta cctatatgtt tctaactgta gttaagt
//
LOCUS       DAFBSV010000121         5342 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.126, whole genome shotgun sequence.
ACCESSION   DAFBSV010000121 DAFBSV010000000
VERSION     DAFBSV010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5342
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.126"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            1..2328
                     /locus_tag="LLB18_002609"
     CDS             1..2328
                     /locus_tag="LLB18_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBK5245571.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            2454..2783
                     /locus_tag="LLB18_002610"
     CDS             2454..2783
                     /locus_tag="LLB18_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBK5245572.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     AEIKTSD"
     gene            2823..3827
                     /locus_tag="LLB18_002611"
     CDS             2823..3827
                     /locus_tag="LLB18_002611"
                     /inference="COORDINATES: protein motif:HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBK5245573.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKTKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            3824..5253
                     /locus_tag="LLB18_002612"
                     /pseudo
     CDS             3824..5253
                     /locus_tag="LLB18_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306286.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
BASE COUNT         1890 a         1030 c         1057 g         1365 t
ORIGIN      
        1 atgaaaatga ttaagaaaac tcaaaataaa atccaacgta tatgtcaaaa acattttgtt
       61 tctagactca aagctgtatc taaaagaaaa tacttacatc ccattatgat ttcgatcatc
      121 ttgattttta ctttcttagg gagcttatca agtatttatg taaacgttta tacagaaacg
      181 tcaaattttg ctaaccaaac gacagaggag acaaatagtc caccctattc tgaaatacag
      241 tccatagaaa gcaccaatca gtctagcaac aacgagacaa cctcaaccac atcctcgact
      301 caactgattg atccgacaga aaaagaaatc acagcagcaa aagcagcagg ggagaaagct
      361 tattcagaaa caggtagaag ccagacattt agtactgttg cggccactgc gaatttcaac
      421 ggacatacca taccagatgg atatacagtg atatatgcca aagatggagt cattgttgcg
      481 gttaacggat cgatgagtgc ggataaaact gcgttacaag gcgtaaccaa agcaatcgct
      541 tttattgata accgtccaga tatccataat ctgtttattg gctccacagt aaatggtact
      601 actatcacat tcccaaaaag tatctatatg ggggtggcta ccgctggaaa tacgatcgat
      661 tcagttacac ccaatgcgga taaaagttat tcttttacac cctcaacatg gggagggctt
      721 cctgccggag gaggtatgag tactttttca atcggtatac agttagcaaa tgatattcca
      781 ttcacggggt actcgatcaa aaatgggcag atcgttgatg gtaagggaaa tgtttcaaat
      841 tttccaacct atcaagcagc aacggttcag gtcaatgcga atcggacagg aactttttct
      901 tatacagtca atggtggagc agcaaaaatc ggaacgtacg ggactacatt atctggaatc
      961 catgtgggtg acaaagtggt tatcactcca acagcagtaa cgggctattc ttttgcacaa
     1021 acaaacggtt ctttcacagc cctagaaagt aacgtcgata cggtgaccta tacaggcaaa
     1081 caaacaccaa tcactattaa gtatcaagac tattttggac agatgattgc tccttctaaa
     1141 ataatgaatc ttacttacgg aagtgctgca caagacctga cgactaatac gcctactatc
     1201 aacggatata cctttacagc tgtttcagcg acagaaacaa agaaccaatc agcaatgagt
     1261 gttttagcta gtttagatac aaatggaaat gtaatcgtaa aggacgcaaa tggaaaacag
     1321 atttctgaag tcatcctata ttataagaca aatgcaacag tatcaatcaa tgcaaatggc
     1381 agtaagtact atgatggtct ttctgttgta ccgatcgtta aatatgcctt taatgataaa
     1441 acagaatcaa catccctttt aaacaatgat ctcagtattg atcaaatcac atggaatcca
     1501 actgatttca aagcgatgaa tgaaaaggga gttgaagtaa ctgcgcctac tgaaattgga
     1561 acctatacgt cttggcaatt gacaaaaagc ggactagcta aactagctgc cagaacaaac
     1621 tatttattta ctatcgtgca gacatctgat gtctatacga ttaagcaaat cagcggtgcg
     1681 gtagagctca gtggcagtaa gacatatgat ggaaaagcag gtgtcccgtc aatccatgtc
     1741 aagctagcag agggtgtcac tagttcgctt actccagtac aagtggcact tagcagtatg
     1801 gattacacag cagatgcaca atcagcaaaa aatatggtta atgctggcag ctatacaatt
     1861 aaactaacga atagcggaat agacaaagtc aaagcagcaa atcccaagtt gtcatttact
     1921 gatatagcca acacatcagg aacttatacc atctataaag ctaacgcagt gattactgtc
     1981 gatgacgctg cctttaatta tgatgcccaa agtcactcga tttcggttgg aaatctccac
     2041 gttaccggtg ttgtcttagg cgaatcattg gattataccc taacagttaa cagccggaca
     2101 gatattggat cacaaatagt aacgattagt ttaggcgaag gaagtgtaaa caataattat
     2161 acgattatcg caacagatac cgctaagttg acgatcaatc cgactctctt gcttccttcg
     2221 acaggtggga taggtctact gccctttgtc tttttaggac tgatctttat tttttctggc
     2281 ttcttttatt ttatccatcg taagaaaaaa gcaggtgaac agcgatgaaa aaaacaaaaa
     2341 atgtacgtgt ggatatattt gctgttctct tttttatcct actggtcttt tttataggtt
     2401 ctccgactgt gtcagctaga gaatcaccta ttacatttac tttgcataat cgaatgttcg
     2461 aaagcgataa gatgccaagt atcagtcaaa acgacggaat aaatatcccg gataactttc
     2521 aaggagtaaa agggttgaac ggcgttactt tcgctatata tgatgtctcg gatgaatttt
     2581 acaagctgcg gtcagaagga agtagtgtgg aagacgcaca aagaaaacta gcacaaaaaa
     2641 gtgatagtga aaaaatactg gcagaaaatg tgacaaaaac agtagacgag gaagagggca
     2701 ttgcttcttt tagtgcatcg gacaaagatg agcaaggtcg tgacgctgtt taccgatttg
     2761 cggaaataaa gacttcagat taagtaaaag aaaaatcagc accatttgtc gttgtgcttc
     2821 ctgtgacaga ttcatctaat cataaattga cgaccatcca cttgtatcca aagagcgaac
     2881 aaaaaatacc tgctgcactc acattaacaa aaacagtaga gaataagcag acagattttg
     2941 cagatgggga taaagttcct tatctcatca ccgtaacaat tcctgagaac atcaacgaga
     3001 taggaaccta tacgatcaaa gatacagctg atcctcagtt atggctagaa ccagaaacga
     3061 tcgatttttt gattggtgga gacaagattc atacatttca cacacaaaaa acaaaacatg
     3121 gttttgtctt atcagattct ggaaaagatc ttagttcgtt tgctgggaaa aaattaacga
     3181 tccgttacca aatgacattg aaagaaaaca gtgaaaaaac gacatttgat aacgatgtac
     3241 gtttgacgac tgacaatcaa acagtagaaa cacatcttgc catccaaaca ggaggcaaac
     3301 aatttgtcaa agtggatcgg caaacgaaac aaaaactagc agatgctcaa tttctagtca
     3361 aaaaaaatga ccaatactta gcgcaagaaa acgggataaa tcattgggta gccaaagatg
     3421 attcaagagc aacgattttt acttccagta aagatggaac attttctgtc catggattgt
     3481 cttttggaag ttacgaacta gtggagatta aaccgcctaa aggatatata ttgagtcaat
     3541 caaccattct ctttgaagtt gaaaaaggca gttatgatcc gcttcatcct ataccattgg
     3601 aaatcatcaa cgaaccaaaa gcaaatccga cgaataatgg aaaaacgcca gttcagatgc
     3661 agacaaatgg tccatcaaat gaaaaaaatg gaggaagctt tccaaaaaca agcgaagaga
     3721 tgcttggagg tttctcaatt ttagggttgt tgctagtcct ttcaacaggg acagcttggt
     3781 tttataaaaa acaacaaaaa ggaaacaata ggagggaaat aaaatgaaaa acatcaaaac
     3841 aaaaatatgg acgtttttag gaactgctat catgctgctt cctttcgttc tcggcctagg
     3901 aactgcagag gtttctaggc cgtatcacct acaccagaaa atgttacggt taatttgcat
     3961 aaattgaaat tcacttcagc accagaaaat caaataaaca acggaacgga attgacattt
     4021 ccgaatagcg aaccgttgaa cggcgttgaa ttcaacgtat atgacatcac tgctacgtac
     4081 tatccaagta aagacacagc agttccagca gacgctacac ccttcgcaag tgtaacgact
     4141 tctggtgaag gattagctaa cctgactctt ccaggtaaat ctgatgggaa agatgctgta
     4201 tacgtctttg tagaaacacc aaagcccggt gtcgaaacgt cgccaaatat cgtgttaagc
     4261 ttaccctttt ataacccgaa ttcatcagac cctgacaaac ctttagacac gattcaccta
     4321 tatgctaaaa atgtcatcaa agaaagcaat atcaaaatcc agaaagctgg gaacttttca
     4381 ggggtagata agttagcagg ggcgcaattc cagatcaaaa attcagagaa tcaattcgtg
     4441 accggttttg atgaaaacac tggtgtcgct ctctatgatc ctgctgagtc agcgttgaca
     4501 ttcacaactg atactgaagg atccatcagt gtcaatggat taatagacgg caattatact
     4561 ttagttgaaa caaaagcacc agatggttat caattaacca atccacaaaa agaaactact
     4621 tttatagtaa aaaacggaaa attgcaacaa acaaccggta tcatccatgg cgcagatgaa
     4681 gccaatcttg ggaatccaaa cggtgtagtc aatcgggaaa atacaactac ggataacacg
     4741 attactgtag aaaatgtcca aaactacggt gatttccact tcatcaaaca agatgtgaac
     4801 acgcaagaaa aattagccga tgcagaattt tctattctaa gagcaaaaga tccaactgtt
     4861 aaattaatga aaaaaatagc aaatcttgcc tcaggagaat acccatatgc ttggtcagat
     4921 gaagtcacag gttctgactg ggaagaagtg aaattgattt ctgattcaga agggaaattt
     4981 tcaatcgaag ggctgaaaca aggggcatac tgccttcaag aaacaaaagc accagaaggc
     5041 tacgcattac ctaagaatga agctgcgtac actgaattta cagtagatga tgatccaaca
     5101 acttctgatg aaacaacgat cgataaccaa cctaaaggaa tcttgccttc aactggtggt
     5161 atggggatca tcgtattcat cttggtaggt actgctttag ttggaggagc agtgatctac
     5221 ttcaaaaaac gccatcaaga aacagaagct taaactattg gaaacaaaaa tcatacgata
     5281 aataaacgat agtgattcaa atggggagaa aggttgtgac aagtggtcgg tctcttggta
     5341 tt
//
LOCUS       DAFBSV010000122         5204 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.127, whole genome shotgun sequence.
ACCESSION   DAFBSV010000122 DAFBSV010000000
VERSION     DAFBSV010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5204
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.127"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            155..316
                     /locus_tag="LLB18_002613"
     CDS             155..316
                     /locus_tag="LLB18_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBK5245574.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            335..1612
                     /locus_tag="LLB18_002614"
     CDS             335..1612
                     /locus_tag="LLB18_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5245575.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1622..2278
                     /locus_tag="LLB18_002615"
     CDS             1622..2278
                     /locus_tag="LLB18_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5245576.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2278..3654
                     /locus_tag="LLB18_002616"
     CDS             2278..3654
                     /locus_tag="LLB18_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5245577.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(3940..>5204)
                     /locus_tag="LLB18_002617"
     CDS             complement(3940..>5204)
                     /locus_tag="LLB18_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS1182 family transposase"
                     /protein_id="HBK5245578.1"
                     /translation="FEDIFAYILEQAVKAGFVTEDNLYLDSTHIKANANKHKFTKEMT
                     HDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPESGYYVKGERE
                     KQFAYSAHTSCDDNGFILSTIITPGNIHDSQVAFQLVKQSKRLFPEINCVVADAGYKT
                     PKFVHFLTHLNLRPCLPYSRPKGKKGLLSKNEFLYDEYFDCYICPQDQMLAFSTVTRE
                     RYREYKSNPKECVNCPLLNQCTKSKNHQRVITRHVWGDLMDEVEHLRLTDLNKSIYKK
                     RKQTIERIFADAKEKHGMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFF
                     CSKIRNEVDKKLFQARVTSLEQLLSTVCDVGDISFSIRNQLRFKRSLPVSGNINVYFT
                     KARFKRLIAITVSSIVMFLWLFRMGVIP"
BASE COUNT         1921 a          680 c          923 g         1680 t
ORIGIN      
        1 ctgcgcgagg cttaccagcg agatagagat cgacgatttg ttgtttgaat tcttttgaat
       61 aggttcttcg ttgacgtctt ggcatgaaaa atcctccagt gtgtttttta ttattctaca
      121 caccttattt tttctgtcta gtctagtgta gccgattcag gataaggata agtgtattaa
      181 ttgtggaaaa tgtaaaaaag tttgccaaat gaataaagat tcagttgaga attgcaatca
      241 tctggagtgt atcagatgtg gacgatgtaa aaatgcttgt ccagtggatg caattagtta
      301 tggagtaaga aaatagagag gagtagttag gaaagtgata aaaaatgcta tagcatatat
      361 tacaagaaag aaaaatagaa ctttaataat ttttatcata ttaactatag ttctttcttg
      421 cttgtattct tgtttaacaa taatgaaatc aagcaatgaa atagaaaagg ctttatatga
      481 aagttctaat tcttcaatat caataacaaa aaaagatggt aaatatttta atgttaatca
      541 atttaaagat attgaaaaat taaaagaaat tgaagaaaaa ataattcaat atgatggatt
      601 agcaaaatta aaagatgcta aagtagttag cggagaacaa agaataaata gagaagattt
      661 atctgacgaa tttaagaatg ttgtttcact cgaagctaca aataatacta aaagaaatat
      721 tttatttagt agtggagtat ttacaattaa agaaggtaaa aatatagaag aaaatgataa
      781 gaattcaatt attgttcatg aagaatttgc taaacaaaac aatctaaaat taggtgatga
      841 agttgatctt gaattactag atattgaaaa aagtggaaaa ataaaaagtc ataaatttaa
      901 aattataggg atcttttctg gtaaaaaaca ggaaacatat acaggattat cttctgattt
      961 tagtgaaaat atggtgtttg tagattattc aacaagccaa gagatattaa ataattcaga
     1021 aaataatgaa attgcaaata aaattttaat gtattctggt agtgcagaat ctacagactt
     1081 agccttaaac aaattgaaag agcttaaaat tgatgagtca aagtattttg ttgaaaaaga
     1141 ttctaatgcg tttgaagagt ctttagagtc agtgagtgga ataaaatata taataaaagt
     1201 aatgacttat tctattatgt taggtgggat ggttgttctt tcattaatct tgattctatg
     1261 gttaagggaa agaatttatg aaataggtat attcttatct attggaacat ctaagataca
     1321 aattataatg caatttatat tcgagttaat attcatatcg ataccaagta taatatcttc
     1381 cttattttta ggaaatgtat tactaaaagt aattgtagat ggattcatta actcagagga
     1441 ttcaatgatt tccggtggaa gtttaataaa taatagtagt tttatgtcaa atataacaac
     1501 acttggacaa agttatttaa tattaataag tattattgtt ttatcagttg tatttgcttc
     1561 ttcattaatg ttaatcaaga agcctaaaga aatcttatca aaaataagtt aggagaaaat
     1621 aatggatata ttagaaataa agaatgtagc atatagttat gcaaattcta aagaaaaagt
     1681 tttgtcagga gtaaatcaaa aatttgaact tgggaagttt tatgcgatag taggaaagtc
     1741 aggaacagga aaatctacac ttctttcctt acttgctgga cttgataaac ctcaaacagg
     1801 aaaaatattg tttaagaatg aagatataca aaataaagga tatagtaatc atagaaaaaa
     1861 taatatatct ttagtatttc aaaactataa tttaatagat tatttatcac caattgaaaa
     1921 tattagatta gtaaataaat cagcagatga aagtatcttg tttgaactag gtttagataa
     1981 aaaacaaata aaaagaaatg ttatgaaatt atctggtgga cagcaacaaa gagtagctat
     2041 tgctagagca ttggtatcag atgctccaat aatactagct gatgagccta ctggtaatct
     2101 agacagtgtt actgctggag aaataattaa tatattaaag acattagcta aagatagaaa
     2161 taaatgtgta atagttgtaa cacatagtaa ggaagtagca gattctgcgg atatcatttt
     2221 agaactaagt ggtaaaaagt tgaaaaaagt aaataaaatg aatttggagg ttgaataatg
     2281 ataaaaaatg catttgctta tgtaactaga aaaagtttaa aatcattaat tatcatatta
     2341 gttattttat ctatgtcaac tttaagtctc attagtttat ctattaaaga tgctacggac
     2401 agagcttcaa aagaaacatt tgctaatata acaaatagtt tttctatgga gataaataga
     2461 caagtaaatc caggaacacc tagaggtggg ggaaatgtaa aaggtgaaga tattaaaaag
     2521 atatctcaaa cagatagtat agactcctat gtaaaaagaa taaacagtgt tgcagattta
     2581 gttgattatg atattattga aactcaagag actcttgcga atcaatcacc tgaaagagca
     2641 aagaatttta aaagaacagt tatgttaact ggggttaacg actcaacaaa agaaacaaaa
     2701 tttgtatcag aagcatataa attagtagaa ggaaagcatt tagaaaatga agataaaaat
     2761 aaaatcttaa tgcataaaga tttagctgaa aaaaataacc ttaaagttgg agataagata
     2821 aaaataaaat ctaatttatt tgatgctgat aatgagaaag gtgcagatga aacagtagaa
     2881 gtagaaatta aaggtctatt cgatgggcat aatagcggtg tagtaagtgc agcacaagaa
     2941 ctatacgaaa atacattaat cactgatatt catacagctg ctaaagttta tggtaatacc
     3001 gaagatacag ctgtatacca agatgcaaca ttctttgtaa aaggtgataa gaatcttgat
     3061 agtgtaataa aagatcttgg gaaattagat ataaattgga gagaatataa tttgattaaa
     3121 agttcatcaa attaccctgc attacaacaa tctatatcag gtatttactc aatttcaaat
     3181 aaattatttt ttggctcatt aatatttgca ggagttgtag tttcattatt attattctta
     3241 tggatgaatg ctagaaagaa agaaatagca gtattactat cattaggtat atcaaaatta
     3301 gaaatttttg gtcaattcct aattgagatg gtatttatat caatccccgc attcgttggt
     3361 tcctatttct tagctcaata tacagctgac aagcttggga ataatatatt gaataaggtt
     3421 actggtgata tagctaaaca aatagctaaa caatctgcat ctagccaatt aggtggtggg
     3481 gcagaagctg aaggatttaa caagacatta tcaagtttag atatcaatgt attacctaaa
     3541 ttcatgattt atgtagttat atttatgagt ttagtacttc ttgtatcatt gattatttct
     3601 tcattcaata tattaagaag gaatccaaaa gaattattaa ttgacaataa ttaaaatttt
     3661 cggtgctttt tagcaccaaa aatgagagtg taatataaac cgtgtaagta accatcaatc
     3721 ctaggcgggt ggttgcttca cggtttttat ttttctaaaa taagatcaag aggtgattac
     3781 acgatggcta gaaagaaaag aaatcctgat gctgagaagt tagctgaatc cattttgaat
     3841 acttatcaac ccgaatctgt agaggatatg caagatgttt taaaagatgt gtttggtccc
     3901 ttatttgaaa aaatgcttca aggagaattg aataaccatt tagggtatga cgcccattct
     3961 aaagagccaa agaaacatga caatcgacga aacggttatg gcaataagac gcttaaaacg
     4021 agctttggta aagtaaacat tgatgttccc agagaccggg aggcttcttt tgaacctgag
     4081 ttgattccta atagaaaacg agatgtctcc gacatcgcag actgtagaca aaagctgttc
     4141 caaactcgta actcgagctt ggaacagctt tttatctact tcgtttcgaa tttttgaaca
     4201 aaaaaataaa ggctccttgc ctttccatag ccaggtggct aatttcttta aattcattgc
     4261 agcaaacact agcatcgtat gcgtcgcgac tttttccaag cctcgatact tggtccaacg
     4321 catcccatgc ttttcttttg catccgcaaa tattcgttca atcgtttgtt tccgtttttt
     4381 gtaaattgat ttattcagat ctgttaggcg aagatgttcc acttcatcca tcagatctcc
     4441 ccaaacatgt ctcgtgatga ctcgttgatg atttttactt ttggtacatt ggtttagcag
     4501 aggacagttc acacattctt ttggattgga tttgtattct cggtaccttt ctcgagtaac
     4561 cgttgaaaaa gcgagcattt gatcttgcgg acaaatataa caatcaaaat actcgtcata
     4621 gagaaactca ttttttgata atagcccctt tttccctttg ggccttgaat aaggcaaaca
     4681 aggtcgaagg ttcaaatgag tcaaaaagtg aacaaactta ggtgtcttat acccagcatc
     4741 agcgacaaca caattgattt caggaaaaag tctcttcgat tgtttgacga gctgaaaggc
     4801 gacttgactg tcatgaatat ttccaggagt gatgattgtg ctaagaataa atccattgtc
     4861 gtcgcatgaa gtatgggcag aataagcaaa ttgtttttct cgttcgcctt tgacgtagta
     4921 gccgctttcc ggatcagctt tacttatttt tctttctttc agcttcactt ccttttctaa
     4981 gtccaaagta aaagggcgtt ttccagcctc tattcgttga cgattgatct catcttctaa
     5041 ttcatcctga taggctttcg cttcatcatg ggtcatttct ttcgtaaact tatgtttatt
     5101 ggcgttagct ttgatgtggg tagaatccag atacaaatta tcctctgtta caaaacctgc
     5161 tttaactgct tgttctaaaa tataggcaaa aatatcctca aaca
//
LOCUS       DAFBSV010000123         5067 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.128, whole genome shotgun sequence.
ACCESSION   DAFBSV010000123 DAFBSV010000000
VERSION     DAFBSV010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5067
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.128"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(218..721)
                     /locus_tag="LLB18_002618"
     CDS             complement(218..721)
                     /locus_tag="LLB18_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBK5245579.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(844..1608)
                     /locus_tag="LLB18_002619"
     CDS             complement(844..1608)
                     /locus_tag="LLB18_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBK5245580.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLADVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            1716..1991
                     /locus_tag="LLB18_002620"
     CDS             1716..1991
                     /locus_tag="LLB18_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HBK5245581.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            complement(2192..2539)
                     /locus_tag="LLB18_002621"
     CDS             complement(2192..2539)
                     /locus_tag="LLB18_002621"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245582.1"
                     /translation="MIPSVSFLFKKLKTFFILPEIEESNELTASDRSAFLLPVFNTWG
                     KAPQKQPYRRCSKVSFLVLRQIYAKMWKAIFTKFSLILKTKRLFHNQSLMLDADQLFH
                     NLIDGVLSAASRY"
     gene            2707..3636
                     /gene="yidC"
                     /locus_tag="LLB18_002622"
     CDS             2707..3636
                     /gene="yidC"
                     /locus_tag="LLB18_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBK5245583.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADNKQPKNSTNNKGRNAGKQQKRK"
     gene            3739..5067
                     /locus_tag="LLB18_002623"
                     /pseudo
     CDS             3739..5067
                     /locus_tag="LLB18_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012008915.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
BASE COUNT         1605 a          972 c          948 g         1542 t
ORIGIN      
        1 attttgcaca actcatcagt ccttattgac aaagagccga caaaagtcgt gtcaaagtcc
       61 cttgtttcga atgaatggtg ttcaaaagct tgcatctgca gtaataagcc gaaacttcac
      121 aaaaatttga gaagtaattt tcgtaaattc cttcttattt cttgaagctg accacttctg
      181 tcacaacctc aatatggtct attattggtt ttacctgtta aatcgaggat tctttcccaa
      241 agtaacgttg ccatctctta cgcatacttg cagacatggg ctgagccgct tctttgactg
      301 cgcagtattt gtccacgaat gtcacaatat atccttcttt atacttaggc ggtgcgatcg
      361 ttgcacccca catgtgcttc aaaatgatat ctcgctcaag atccgacaaa tcggtgattt
      421 tttctgcatt ctttacagca attcttggat ggatatacgc atgtgtcccc tcgtcaaatt
      481 tcgtcgtacg ccaatcatag tagaacagat catgcaaaag tccagcacgc gctgttgctt
      541 tagcattgcc accccatttt tttgcgagca gataactata gtaagaaaca ctgatggaat
      601 gctccaaacg agtggaatga acatgctgtg tgtaattcgc taattttttc actgcttctg
      661 tttctaaaag atcttgtaca taagacatat attcttcgtc ttcacgccat ttttctgtca
      721 taattatcga tctgccacct ttttgaattt cattttcttc tgaaattgat ctaagtatac
      781 caccagtgtt cgtattattc tagtcgctct agataaaata gctaaagctt aatagttcct
      841 taatcataaa gaaaaatgat aaagaacgat ccctgctgcg actccgacat tcaatgattc
      901 cgcatttcct ttcattggga tatatacgtt ctgatcagtc aaagacaaga tttcctgact
      961 gactccctga ccttcgtttc ccatgattat agcgaaatcc tctgtttttt ctactttgtc
     1021 taatgcatgt gcttcttcat ttaattctgt accgtacacc gtaaaccctt tgcctttcat
     1081 tacagggatt acatctgcca aatctttttg taacacaggc aaatgataat tgcttccctg
     1141 catgcttcgc agcacctttg tactataaat atctgccgtt cctttaccta ataaaacacc
     1201 agccatacca aacgcatctg ccgtacggat catcgttccc acatttccag gatcctgtac
     1261 attatctagt aaaagccagc ctcctgaaaa atctggcgta tcttcagatg ttaacgtcat
     1321 cactgctaag atcccttgcg gtgtaggtag atctgacata gcggtcatga cctcatctga
     1381 aactagaaaa gtagaaatct ctttgtttac agccagccag tctccccatt ctttcatacc
     1441 tctctgtgtc acaaaaagtt cttttatttc tgcatcagac gacgcagctt cttcgatcag
     1501 atggaaccct tccaaaagat attctgcctt ttcttctctg tatttctttt tatgtagttt
     1561 ttttaattct ttgattcttg gattttttgc tgattggatc tctttcacat tccttcacct
     1621 cacctgatta tatcatggaa taggtgcttg agcttgtttc atcctaaaaa aatcggtatc
     1681 attgatttat aaaacaggaa agaaaggtga cgaacatgcg caaagttaaa atgaatgtcc
     1741 aaggacgtgt ccagggcgtg ggatttcgct atatgaccaa gatggttgct gatcagttag
     1801 gcgtgaccgg aacggtaaaa aacgaagacg acggctcagt cacaatcgaa gcaatcggaa
     1861 atgacgacat catccaaaaa tttatcgaag aagtcaagaa gtctccgagc ccaagtggac
     1921 gagtgcagta tgtggatgtc caagaagatc cgatgattga ggaacgaaag aaatttgatg
     1981 tggtgggata aggttgtgaa aaggtcgctt agttttgagt attaaggaaa attttgtgaa
     2041 aatggctttc cacatttttg cataaatttg acttaatacc gagaaactga cttttgaaca
     2101 ccgtcgataa ggttgttttt gaagcgcttt gcctcgagta ttaaggagaa acattttcaa
     2161 aatagcttct catattttga aatgtaatga cttaataccg agaggcagct gataaaacac
     2221 cgtcaataag gttgtgaaaa agctggtctg catcaagcat taaggactgg ttgtgaaaaa
     2281 gtcgcttagt tttgagtatt aaggaaaatt ttgtgaaaat ggctttccac atttttgcat
     2341 aaatttgtct taataccaag aaactgactt ttgaacaccg tcgataaggt tgtttttgag
     2401 gcgctttgcc ccaagtatta aagacaggta gtaaaaaagc tgatctatca cttgcagtga
     2461 gttcatttga ctcctctatt tcgggcagaa taaaaaaagt ttttagtttt ttaaataaga
     2521 aagaaacact tggaatcact cttttctttc caagtatttc tttcttgatt ttttgtcttt
     2581 tttcaaaatt tttcgctacg aaaaagaaag aatatttata tgaaatttct atgaagttga
     2641 ttgaattcca tgcgcttttt tagtatagtt aagtttgtgt aaaaattata gaagaggaag
     2701 tattctatga ataaatggaa aaactggtta ttgggatccg gacttgtcag tatcctgctc
     2761 tttttatctg gctgtgtgcg gatggattca aacggaaacc ctgacacttc aggaatcgtt
     2821 tatcgagtac tcgtccatcc tatgggccaa gcgattacat atctagttga gaatttcaat
     2881 tggtcttacg gctgggcagt tattgcaatg actgtgatcg tccgtatcat catcttgcca
     2941 ctaggtatca gtcaatcaaa aaaaacaatg atccaatctg aaaaaatgca agcgttaaaa
     3001 ccacaagttg aagcagcaca acaaaaacta aaagctgcaa caacacgtga agaacaaatg
     3061 gcagcacaag cagaaatgca acaagtatat cgcgaaaacg gattgagtat gaccggcgga
     3121 atcggctgtc tgcctctatt gatccaaatg ccgatcttct ctgccttgta ttttacggct
     3181 cgctacacag aaggtatccg tgaatcatct ttttacggca tcgatctagg ctcaccaagt
     3241 atggtgcttg ttgccattgc aggggtcgct tatctgcttc aaggatatat ttcaacaatc
     3301 ggtattcctg aagaacagaa aaagacgatg cgtacgatgc tgatcgtctc tcctgctatg
     3361 atcgttttca tgtcgatcag tgcgccagcc ggtgttacac tttactgggt agtgggtggt
     3421 gtgttcagtt gtctgcaaac attcatcaca aacgttatga tgaaaccacg tttgaaagca
     3481 caagtggcag aagagttgaa acaaaatccg ccaaaacaag tcgtcactcc aagaaaagac
     3541 gtgacagaat cggcaaagcc agctgacaat aaacaaccaa aaaacagtac aaacaacaaa
     3601 ggccgcaacg caggaaagca gcaaaagcgg aaataaaaat atatgacaaa aaactgtaga
     3661 caaataaaaa aatttctttg ttctacagtt tttttgttac aatcaaagaa aacgtcgctt
     3721 ttcgaggagg aatgtataat gatgtccaaa taatcaatgg atagtcgaat ggaagaagcc
     3781 aaaatttcgc tagatgcact tgttcctaaa aatcatttgg tccataaaat tgacaaaata
     3841 ttgttatttg attttattta tccaattgtt gaatcaactt actcgaccat tggtcgtcct
     3901 agcgttgatc ctgtcatctt agtaaaatta gtattcattc aatatttatt taggattcgt
     3961 tcgatgcgtc agtccattaa agaagctgaa acaaacctag cttatcgttg gtttcttggg
     4021 cttagtttaa tcgataaaat tcctcatttt tcaacgtttg gtaaaaacta tgtacggcat
     4081 ttcagagaaa ccgattgttt gaacagatat ttatcattat ccttgaacaa gcagttgaag
     4141 ctagatttat tcatgaagaa attttgtata tggattcaac ctatattaaa gcgaatgcga
     4201 aaaaacatat ttttacaaga gaaatggtac ataaataagc cattttatac caaaaacaat
     4261 tgaaagaaaa aattaatgaa gcaagaattg cagaaggcaa acgtcctttt ggttcaatca
     4321 ttcatcagga ggtggtagaa gggaaaatta gtgtcgcaga tccagaaagt ggttattatg
     4381 taaaaacaga acaagaaaaa cagtttgctt attctgctca taccgtttgt gatgaaaatg
     4441 gttttgtatt agatgtcatg attacgcctg gaaatctaca tgacagccga atgctcgtgc
     4501 cacaaatcga acgtgttaaa tcatgttgtg gtgtagctgc tgatgctgcg tacaaaacac
     4561 cttggaacgc caagtattta atcgatcgaa aactacgacc catttttcct tatactcgac
     4621 ccaaaagaag caaagaacgt tttaaaaaga aagattttta ttatgatccc tattataact
     4681 ggtacctatg cccaaatgat caaacacttc agtttcgcac aactactcga gatggttata
     4741 aaaaatatgt atctaaatct tttatttgtg aaagttgtct attattgaaa aattatacag
     4801 aaagccagaa acaccagaaa gaaatacatc gacatattta ggaagactac ttagatgaag
     4861 cagaacattt acgccatacg gtgtacaatc gcgaaaaata taaaaaaaag aaaagaaacg
     4921 attgaacgcg tttttacaga cgcaaaggaa aagcatggaa tgcgctacac caaatatcga
     4981 ggcttggaaa aaaccaggtg catacgatgc ttgtttttgc cgcaatgaat ctgcaaaaat
     5041 tagccatttg gcagtggggg catatgt
//
LOCUS       DAFBSV010000124         4942 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.129, whole genome shotgun sequence.
ACCESSION   DAFBSV010000124 DAFBSV010000000
VERSION     DAFBSV010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4942
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.129"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            475..1425
                     /locus_tag="LLB18_002624"
     CDS             475..1425
                     /locus_tag="LLB18_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK5245584.1"
                     /translation="MKNDIVTYANTKCEEIGISNLEECFFDTNDLSQFLRTGRTNASK
                     LANDLVAKNVLFKINTRPVLFAIKERFEEHFLIPVKDVYESISELKTDLEPNSTDSIL
                     QKMIGYDMSLSDAVEQMKTAVFYPGRGLPMMITGDTGVGKSFFVHTAYQFMKKVNVIH
                     ENAPFKVLNCAQYHNNPELLSGILFGYVKGAFTGADEDRNGLLQDADGGVLFLDEVHR
                     LPPEGQEKLFVYMDGGTYSRVGETIHHASNVRLVFATTEGKEDFLETFMRRIPIHIHI
                     PNIEERGILEKKQIIENTLFSESKNFSKAIDVSPKVTSVA"
     gene            complement(1470..2103)
                     /locus_tag="LLB18_002625"
                     /pseudo
     CDS             complement(1470..2103)
                     /locus_tag="LLB18_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
     gene            complement(2363..2911)
                     /locus_tag="LLB18_002626"
     CDS             complement(2363..2911)
                     /locus_tag="LLB18_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245585.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(2912..3769)
                     /locus_tag="LLB18_002627"
     CDS             complement(2912..3769)
                     /locus_tag="LLB18_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBK5245586.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(4055..4342)
                     /locus_tag="LLB18_002628"
     CDS             complement(4055..4342)
                     /locus_tag="LLB18_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBK5245587.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            complement(4332..4661)
                     /locus_tag="LLB18_002629"
     CDS             complement(4332..4661)
                     /locus_tag="LLB18_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBK5245588.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(4738..4884)
                     /locus_tag="LLB18_002630"
                     /pseudo
     CDS             complement(4738..4884)
                     /locus_tag="LLB18_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
BASE COUNT         1503 a          930 c          706 g         1803 t
ORIGIN      
        1 ttattcaact tatttaggtc ctgcctgcat taccagtcac atgcctgttt aagttatatt
       61 caatttaaca tattagaatg taaacgtaaa taataaaatg attttttaat cattttttca
      121 ttttattcgt tcaatatagt tttcgtgttc taaaagtttt gtcttttttc taagaatatc
      181 ttccaacata tataactctt attctcttct atcttctagc agatgttctg tctttttaag
      241 acctagtata aaaagaatgg gttcattttt tctttcttgc aggatgaggt tttttatata
      301 aactttattt gatataaaga aaaggcattc ataattgtgc tatactacta aaaaatgata
      361 atacagtgaa ttagattagc gctttattaa attaagagga cagcatatcg atattgcttc
      421 cttttttttg ctatttattt aagggataga agtttagaaa ggactgttta taagatgaaa
      481 aatgatatag tgacttatgc aaacacaaaa tgtgaagaaa ttggcatcag taatttagaa
      541 gagtgctttt ttgacacaaa tgacctgtcg caatttttaa gaacgggaag aacaaatgcc
      601 agtaaacttg ccaatgactt agttgcaaag aacgttctat ttaaaatcaa tactcgtcca
      661 gtgttatttg ccatcaaaga gcgctttgaa gagcactttt tgattccggt aaaagatgta
      721 tacgaaagta tatctgaatt aaaaacagac ttggagccca attctacaga ttccattcta
      781 caaaagatga ttgggtatga tatgagctta tccgatgcgg tggaacaaat gaaaactgct
      841 gtcttctatc ctggaagagg gcttcctatg atgatcactg gagatactgg agttggaaaa
      901 agtttttttg ttcatactgc ttatcagttt atgaaaaaag tgaacgttat tcatgagaat
      961 gctcctttta aagtacttaa ttgtgcgcaa taccataata atcctgaatt attgtcgggg
     1021 atactatttg gctatgttaa aggtgctttt accggcgcag atgaagatcg aaatggattg
     1081 ttgcaagatg cagacggtgg agtactgttt ttagacgaag tacacagatt gcctcctgaa
     1141 gggcaagaga aactatttgt ttatatggat ggcggaactt attctagagt cggtgaaact
     1201 atccatcacg cctccaatgt acgtttagtt tttgcgacta cagaaggcaa agaggatttt
     1261 ctggaaacct ttatgcgaag aatccctata catatccata tcccaaatat tgaggaacga
     1321 ggtattttag aaaaaaaaca aattatcgaa aatactctct ttagcgaaag caaaaacttt
     1381 agcaaggcta ttgatgtttc tcctaaagtc actagtgttg cataaatata gtcagaatat
     1441 tctgaattat tattttcttg aaaaaagtaa aaaaaatcgt atcccaaact ttcatctaca
     1501 tttccagaaa gatcttcatg ttgataatca attcctgaat caatgaccgc taccttcaca
     1561 tccttagaac ccttggtttc ttcccaagcg gatggcatgc taatctctct taaattagct
     1621 tgtttactcc aattaggatc gttatcgatt tcctaaagaa tcagttgtat ttggctcctc
     1681 aacatcattc aacggctcta gttcaaccac atagtttggc tctgcataat tgaccatatc
     1741 agaagcatta aatgttctta ctgcctcttc cacactaatt tcttcgttca atttcactaa
     1801 taatacttga tctcgcttat tataatcgct ttcatttgtc ctaagagtca aatctttttc
     1861 caccataact tttacaccca ataaattttg cggtttattt ttctctgttg aaattctttg
     1921 tgtagccttt aaactgacaa ttagctcatt gggtacatac tctatttgag agtcatctaa
     1981 ttggctcata atcctttctt tttggttagt atctgcagtt acttgtttag tatgagccat
     2041 gaacccaaac atactcaccc caacaaccaa tcctaaatat attttctttt taaacttttt
     2101 catctacatc tcctcctaat agttttattt tagagttagc tctattactt atttactaac
     2161 tcaacaacag attatcatac acttattaat gaaatcacaa tatctcatta aaacacaccc
     2221 taaaatcata accgttccta tgctcatttt ttggattttt taatcacgta accagaaaaa
     2281 taaatcccct ctatttcacg caaatcaaag aagaactaag taactaccgt ttaaaggtag
     2341 ttacttagtt cttctttgat tattatctaa ctttattatt cattccccac cctttgcgca
     2401 gtgagtcttc ggtatcttgt tttatctgac tggtagttct tattatttct ccacgatcat
     2461 ctaattctgg aacaattgga tatttttctc tgaacaagtc tagttctttc accacgtcat
     2521 taaacaaatc ttgtttatct tcttgcgtaa gattctgttt aatatactca tctaaagctt
     2581 ttctaagcaa ttcatctctt gtcatattag tctcatactt ttctactaaa actctggaag
     2641 tcgcatttaa caaagtcgac agttttaaag gatgcttggt ggaataaacc ttatcaaact
     2701 ttctgattgg tgcgccaact ttttttgttc ttcctctact ctgtctttca acattggagg
     2761 aagtttttat ttcttgaact tggtgcactt ctaattgctt attttcagat ggtgtaattg
     2821 cttgctgctt tttctttgct tctgcttctt tttttatttt ggcgagtcct ttgttgttcc
     2881 caaaaatatc aagtcctttg atgtcagcca attactccac ctccgcatac caattctcgt
     2941 gttcttccaa ttctttcaaa atactgataa ataattcgtg gcttttgcga tcccattgtt
     3001 ttaagagacc tttctttgtc ttctccatcg taatacctga tccgtcgtat cgttttaagc
     3061 gcgcattttt gagtacaaca tttttaatca aatgttcccc ataaatctct tgggcttgtt
     3121 tatacatttc ctgatctact gcgtcaccgc tttccaacat gaaaggaata acaccagcaa
     3181 catataaatt tgtatcaaat tctttcacaa aaaagtccat atactcaaga tattgcatcg
     3241 catttctcat cgattttact tgggtctgta agacgacgat tgcccaatcc gcaatgtaca
     3301 tcgcggattt actatataca gaaatagaag gtgggacatc taaatagatg acgtcaaact
     3361 catcaaataa tggttctagc ttttctttca tatatttgaa ttgggataat gaatcattat
     3421 attggtcttt gatccaatca tcatacattt caaaggacat gtctgctgga agtatataga
     3481 ggttattgat tactttatag acagcctctt taggtggaag attgtttatc aacacgtcag
     3541 tcacagtatt ttcgtaaaca atcggttcac cttctccgcc tccttcttcg ttagtgaagt
     3601 tcatatgcgt taagttcatc acatcagaag tatttccttg catatccaag tcaattatca
     3661 aggttctttt tccttcatta actgctgatt caaaccctaa catttgcgcg cacgtacttt
     3721 tacctacgcc acctttaaaa ttaccgatta catatttctt cgctaccacg ttcctacctc
     3781 ttttctttta gcaatattca tttgatacta ttataacata tttattttta gttactacca
     3841 aaaaaaagat atatatgtac taccttataa ttaataagta aaaggtagta cataaataag
     3901 gaaaagctga aatatattga tttatagctt tcctcaaagt aatgacgtta tttaatttat
     3961 cgagaagcag agaatactcg cgactttagt catgtagacg aatcagattt tcgataaaaa
     4021 agaagccgtc cttcttaaga acgacaacaa atcactagat taattttttc aactgttcat
     4081 aaaagttttc atgcgttcca cataacaata ctggaataac cttgttttct ataatctcgt
     4141 aagctactct atatgttgtg cccgcatatt tgaacccact agaccaaata cctgataaat
     4201 ccccagtttt ttgttcaccc ttatatggat caatcgcaat ttcatcataa attaaattca
     4261 aaaatttttc tttcaatggc ttctctttta gcttttttaa atacttaatg acatgttttg
     4321 aaggaacgat ttcataagcc aatttctgtt gccaactcct ctttagtcat tactttagaa
     4381 ttagtaagtg tatcttcagc aatatctcta aaggaagaat gcattttgtt ttttctattc
     4441 ttaaattcta caagaatctc atctttatcg tagccttctg caattatatc agacaaaata
     4501 tcttcgctaa aatcataaaa ttctttttgt ggttcaacaa attcataaag aataccattc
     4561 tctaccaact ttgcttcaac ttcgactcca ttaggaacat taaaatcttt aggtactgtc
     4621 aacatgattg aattgccttg ttttcttgtt tttgtaatca tttaaatccc tcatttctaa
     4681 cagtatgtaa ttacttagta aatacattat accacgagat aatgtattta caagtaatta
     4741 ctgtgactcg taatgcgtcc ttgctgaata aatttcaacc acgtgttcat cttcatctac
     4801 cttataaaca acccggtgtt gtctattcaa tcttctaaaa tacctacctt catgtgtagg
     4861 ttttaacttc tcaaatgatt gggttctgtt gcaaagtttt aaataaagaa taaaatccct
     4921 tacggtatct atgatttaag ct
//
LOCUS       DAFBSV010000125         4617 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.130, whole genome shotgun sequence.
ACCESSION   DAFBSV010000125 DAFBSV010000000
VERSION     DAFBSV010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4617
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.130"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(15..962)
                     /locus_tag="LLB18_002631"
     CDS             complement(15..962)
                     /locus_tag="LLB18_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBK5245589.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(1140..1943)
                     /locus_tag="LLB18_002632"
     CDS             complement(1140..1943)
                     /locus_tag="LLB18_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HBK5245590.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            2089..3003
                     /locus_tag="LLB18_002633"
     CDS             2089..3003
                     /locus_tag="LLB18_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBK5245591.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            3051..3521
                     /locus_tag="LLB18_002634"
     CDS             3051..3521
                     /locus_tag="LLB18_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBK5245592.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            3606..4214
                     /locus_tag="LLB18_002635"
     CDS             3606..4214
                     /locus_tag="LLB18_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBK5245593.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            4348..4548
                     /locus_tag="LLB18_002636"
     CDS             4348..4548
                     /locus_tag="LLB18_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBK5245594.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
BASE COUNT         1512 a          716 c          912 g         1477 t
ORIGIN      
        1 attgttttca gctattaata tcctgcagac aattttactt gattggtttg aagctcatgg
       61 gtggcaaagt agcttttcag attggttaaa aaaatagcca ttaatttctt ttgaaaatca
      121 ggtgtcaaac ctgcaatgtg ggaagtaatc agtacattgt ccattttcca aagaggatga
      181 tcttgtggaa gaggctcttc ctcaaaaacg tctaatgctg caaaggaaag ttgctggtta
      241 tttaaagcct gcaccagatc ttgtgtctta acagaagcac cacggccaac attgatgaat
      301 acagattttg gatcaaagtg ttcaaacata tgctgatcaa agagcccagt tgtttcctcc
      361 gttagaggta agatattgac tacgaaatct acttcaggaa gaacttcctt tagttgattt
      421 aaagaaaaag tcttttccat tccttctgct ggatgaccgg atgtattgat tccatagcag
      481 ttcatgtcta atgctttgca tttttttgca atcatttttc caatatggcc agttccaatg
      541 attagtattt ttttcccttg gatagattgg taatggaccg atgaacctaa ccatttcatg
      601 tcactctgtg ccttttgtgc ttgaaaaaga ccacgagaat acccaaggat gattcctaag
      661 acatgctccg taatcgattc actgtggatg ccactaccat ttgaaagtaa aatatgtttc
      721 tttgaaaaag tctcaagggg tagctgatca acaccagctg agatagattg gacccatttc
      781 aaggtagaag aggctaatag tttttcttgg tagtctgagt tccagcccaa actgatctct
      841 acattttgta gatcctctgg ttgtaattct gttttaaaga tataaccagg cgctatagta
      901 tggatttctt cgataaattc atcacgaaat ggacgatctg cataaatgat tctttctgac
      961 atagttaatt tcccgccttt ctttactcta agtgtagcgc atacaagaag aactttgaag
     1021 cgccttgctt gttttttgag aaagaaatat ttttcaaata aaaaaggggc tgtgacaaaa
     1081 aaatgtcaca acctctaaaa gggtctattg aagtagaaat aacgagttgt ctttatttct
     1141 taattgatcg atatttttgc ccatcctttg acagcttgag caaaaataaa gattcctgca
     1201 aaagcaatga aggcgctagt gtcaaaagaa ggaagaaaga ccatcaagat tgttgcaatt
     1261 atagtaggca atgaaattga atagatcaat gtttttaaac aatcaagaaa agtagctttt
     1321 gttagtcgaa agcgtgcata gagaaaagca gcaatgttgg taaatagcaa agtgatcagc
     1381 agattcagaa aactaggata aatagaaaat ataaatgtca ggacttttat ccaaagtggt
     1441 atagatgctt cacttaaaaa agaacggagc tgcttacctg ttaagttttt taaagattca
     1501 ttggtgtagg gaagttctaa ttggttattg ttcaacaaag cagaagtcgt gcctgtatta
     1561 ggaagagcta tgataagttt gttttttaac atcccgacac taacaaaatt ccccatcaaa
     1621 tcagtagaga tgtcctgttc tgttcgtttt ccctctggat caaatgtgaa gataatggag
     1681 tttgtttggt aaatgaatcc ttctttttct tcggtttgaa gctgcccgtt ttggattgta
     1741 aaatcaggaa tgcgagtagc aatcttttgc ccatccaatt gaatgttgtt taagacttga
     1801 aaaacttgaa aagagattgg caaagccata attatactca aaactaaaag atagacaatg
     1861 gctttccaaa atgggacatt tctcgcctcc tttaggtctt tgaatcgtat aaaggaactg
     1921 ataattaatt gttttgttgt cataagtact cctcatctag tagtgtcatc acttgcaatt
     1981 ctagcgaagt atcaagtgaa atacaagtgc tttaaggaaa cagctgaatg attggtgaaa
     2041 tatcaaaaaa atgttattct tgtctaaaga ctatccaata taaataaaat ggaggaagga
     2101 atagtgccta cacagccaca gagatcatca aaaaaactat ttggagtagt ggttttgaat
     2161 gcggtgatca ctttatcaga atttattgga gggattatgt cagggagttt gtctcttgtt
     2221 tcagatgctt tccataacct tagtgataca ttggcaatta ttttttctta cggggcacaa
     2281 aaaatggccc gaaaagaagc aaataaaaaa cgtacgtatg gctaccagcg tttagaaata
     2341 ttgagtgctt tcatcaactc attcatattg atcatattat ccttgttttt aaccgttgaa
     2401 gcattcaagc ggttcacttc accagaaaag ataaatagtc atttgatgct aacagtagca
     2461 gttattggat tgctcgcgaa tttgttctca gtattattat tacgacaaga agcagatgaa
     2521 agtttgaata taaaatctag ttatttgcat ttgttaagtg atacactgtc ttcggtaagt
     2581 gtgattatcg gagcaatttt gatccgtttt ttcgatatct actggatcga tccagttatt
     2641 acactgatca tttcgatata tatattgata gaagcgataa tggtgatcaa aaaagctgcc
     2701 gctattttga tacaaagtgc acctgctatc gactatgaaa aaatggaaca agaaattgaa
     2761 gcaatcgatg gggtaaagga tgttcatcat gtccatattt ggcagtatag cgaaaagata
     2821 attattttcg acggacatat tgattttgaa gatcagctac taagcgagat tgaaaagata
     2881 tatcctcgta taatttcttt attaaaatta aaatatggta ttacacatgt gacgatccaa
     2941 gcagagacaa aggcaaagga tcaaaaaaaa ttaatttttt taaataaaga tgaaagttat
     3001 tgaaatatag agtatgataa ataagaattt ttaataaggt aggttggctc atgaagcagt
     3061 atcgacagtt aaaaggatat ttagaagcaa aaggatattg ggagatacta gtctatctct
     3121 tttttggtgg tttggctacg attgtaaatt ttgttagttt tgctctcgca cgccaatatt
     3181 ttgatttaag tatggcctta tccaattcta tttcgtggtt ttgttctgta ttgtttgctt
     3241 ttgtaacgaa caaactttgg gtattccatt caaaatcacc gaattttaca catgcactta
     3301 ttgaatgcgg taagttcttc ttctaccgta tcctttctta cggattggac atgggggcaa
     3361 tggtattgtt gatcaatgtt atgaacagca atgagtatgt ggcgaaaatc atcactcaaa
     3421 ttattgttat ccttgcgaac tatattttca gcaagttgtt tatttttaaa gaaactgagg
     3481 tttttgaaga agaagtaggt caaagtgaaa aagacgacta ggcataacaa ttgaagaatt
     3541 tccttctctt tgttactctt tgtaatgtag acattattaa gaaaacattg aggaggaatt
     3601 tttttatgac ttacacatta ccagatctac cttatgcata tgacgcattg gaaccttata
     3661 ttgacgaaga aacgatgcat ctgcatcatg ataagcatca caatacttat gtgacgaatt
     3721 taaattcagc aattgagaaa tacccagaat taggcgaaaa aacaatagaa gaattattat
     3781 ctgatatgga cgctattcca acagatatca agacagctgt acgtaacaat ggtggcggac
     3841 atgctaacca ttcatttttc tgggaaatca tggcaccaaa tgctggtggc gaacctacag
     3901 gagaaataaa agaagcgatt aatgaagctt ttggtgattt ttcttctttt aaagaagaat
     3961 tcaaaaaagc agccgctgga cgatttggtt ctggatgggc ttggcttgta atggaaaatg
     4021 gaaaattagc tattacctct actgcaaatc aagattctcc attgatggaa ggaaagacac
     4081 caattctagg tttggacgtt tgggaacatg cttattattt gaaatataaa aatgtccgac
     4141 cagattatat tgcagcattc tggaatgtta ttaattggga tgaagtaaac aaacgtttcg
     4201 aagcagcaaa ataaccattt cctccgtcat atcagtctta aaaataattt ggaaaataaa
     4261 agagcgaaag cttgctagcg ttttctaaat tgggtataat gttcttgcaa ggttacttgc
     4321 aagaactttt ttggaggata tacatttatg gaacacggaa cggttaaatg gttcaacaat
     4381 gaaaaaggat ttgggtttat tacagtagac ggcggagatg acgtatttgt tcatttctca
     4441 gcaattcaag gagacggctt caagagccta gaagaaggtc aagaagtaga attcacgatt
     4501 gttgaaggtg cacgcggacc tcaagctgct gaagtgacta aattataata atttgttgaa
     4561 taaagacacg acttcttaga gagtcgtgtc tttttgtcta tttatgaagt ttttaga
//
LOCUS       DAFBSV010000126         4507 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.131, whole genome shotgun sequence.
ACCESSION   DAFBSV010000126 DAFBSV010000000
VERSION     DAFBSV010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.131"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            132..1976
                     /locus_tag="LLB18_002637"
     CDS             132..1976
                     /locus_tag="LLB18_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK5245595.1"
                     /translation="MNYKQTAEEVLQYIGGEENISHLEHCSTRLRFTLKDNSKVNMSQ
                     LEKVDGVMGVRQNVQCQVIIGNDVVEVYDEVKALLGDNVSNTEEAPKQKQKLGSVLLD
                     FIISIFQPLIPAIAGGGVLKSLLLLASILGLISDQSQTYQILNLVGGAPLYFLPILVA
                     MTTANKLKVNQLVAVSAVGALILPEMTAMLAEGATFLSFGLDNIAYASQVFPAILTVL
                     FYAQLEKWFTKVSPKPIRIFFVPMMSLLITVPIALLLLGPLGYNVGTAFSSIIVSLYN
                     QFGWVATGVLAAVLPLMVVTGMHKAMIPYAVSSMSELGAELLYLPASLAHNISEAGAC
                     FAVSIKTKDKKLKSTAVSAGISALFGITEPALYGVTILHKRVLYAVMFSSLIGGAFAG
                     IVALQAFALVGPGIASITMFADKADPMNLVWAFAVSGISFVVAFAAALVLYKDKEVVN
                     EVETKMETAVVSDAVLSSPVNGKVISLSEVKDTVFSSGMVGDGVAIIPEEGILVAPED
                     GEITMVFETKHAIGLKTANGAELLFHIGIDTVQLEGKGFEAFVRSGEKVAKGQKLIAF
                     DIDLIKEAGFDPTVICVVTNKDNYTIRSFNLEKLVTNDSDLLAISPIA"
     gene            2032..3498
                     /locus_tag="LLB18_002638"
     CDS             2032..3498
                     /locus_tag="LLB18_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016620473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBK5245596.1"
                     /translation="MTNTTSFPKGFLWGGAIAANQVEGAWNVDGKGLSVADMATYKPN
                     LDNKDFAAHMHVTLQSIKEASEDKSDKWYPKRRGVDFYHHYKEDLALFAEMGFKTLRL
                     SIAWTRLFPTGEELEPNEKGVAFYENVFKEMQRLGIEPIVTLSHYEMPLALAVKYNGW
                     VERRVIDDFVRFANVCFDRFGKYVKYWLTFNEIDSIHRHPFTTAGIIQEKSAEGQEAQ
                     DIYQALHHQFVASALVTKDAHEKIPGSQVGCMLTKLMTYPLTCAPEDVELTLKKNLEN
                     NFYADVQVKGEYPALIEKDLENRGIQIKMEDEDREILKKHTVDFVSFSYYMSMAESAD
                     PNAERTPGNTVLGVKNPHLPSTDWGWQIDPKGLKISLIELYDRYQVPLMIVENGMGAV
                     DQVVDGKIHDPYRIDYFKAHFQQMKEAIDEGVDLIAYTSWGPIDLVSAGTSQMSKRYG
                     FIYVDADDEGNGTYNRLKKDSFNWYKEVIETNGASLFE"
     gene            3535..4377
                     /locus_tag="LLB18_002639"
     CDS             3535..4377
                     /locus_tag="LLB18_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBK5245597.1"
                     /translation="MISIKKVLNSSVVLVEENGKEMIALGKGIGFGQKAGDEISGDKV
                     DKIFLPFEEKKSSQLLELVEEIPIEFFEITRTIVFEAEKGLDKKLNPGVYLTLTDHLH
                     FAVERAQKGVNIANRLYWEIKIYYPKEFQIGKYALTLLNEQYGIDLPKEEASNIAFHL
                     INAQSEDPDSGAGFKYAKMIGGIVNLVRYSLQKDIDTNSIHYARFITHVRFFVERYYS
                     DALLDDGEEEFYNQMWILYPSAMESAAKIKDYIEKVYHKTIPNDEVVYLGVHINRLMK
                     HANG"
BASE COUNT         1446 a          738 c          976 g         1347 t
ORIGIN      
        1 ataacaatgt atgcgtttca atacacgttt gccttgttgt caatttattt agtttctgcc
       61 tgttttttgt gttgaggatg gccacttcga ctcaaaagtt catcactcaa aaaagaaaag
      121 agggaaacac catgaattac aaacaaacag cagaagaagt attgcagtac atcggtgggg
      181 aagaaaacat atcccatttg gagcattgct caactcgttt acgttttacg ttaaaagaca
      241 acagcaaggt aaatatgagc cagttagaaa aagtggatgg cgttatgggc gttcgccaaa
      301 atgtgcaatg ccaagtaatc attggaaacg atgttgttga agtgtatgat gaagtgaaag
      361 cgttattagg tgacaatgtt tcaaatactg aagaagcacc aaaacaaaaa caaaaattag
      421 gttcagttct attagatttt attatttcta ttttccaacc tttaattcct gcgattgcag
      481 gtggaggagt attgaagtcc ttgttgctac tagcttctat cttagggctg attagtgacc
      541 aatctcaaac ctatcagatt ttaaatttgg tcggcggggc accgctttat ttcttgccta
      601 ttctggtggc aatgactacg gctaataaat tgaaagtcaa tcaattggtt gcagtatctg
      661 ctgtcggtgc attgatcctt cctgaaatga cagctatgtt ggcggaaggt gctacattct
      721 tatcttttgg attggataat atagcgtatg catctcaagt attcccagcc atcttaactg
      781 ttttatttta tgctcaactt gaaaaatggt ttacaaaagt ttcaccaaaa ccaattcgta
      841 ttttctttgt acctatgatg agcttattga ttacagttcc tattgctttg ttgcttctag
      901 gaccattagg ttataatgta ggaacagctt tctcttctat cattgtgtct ttgtacaatc
      961 aatttggatg ggttgcaacc ggagtcttag cagctgtact gccattaatg gttgtaacgg
     1021 gtatgcataa agcaatgatc ccttacgctg tttcatccat gagtgaattg ggtgcagaac
     1081 ttctttatct cccggcttca ttggcacaca atatttcaga agctggcgca tgctttgctg
     1141 tcagtatcaa aacaaaagac aaaaaattga aatctacggc tgtttctgcg ggtatatctg
     1201 cattattcgg aattactgaa ccagctcttt acggggtaac gattctgcac aaacgtgttt
     1261 tatatgccgt tatgttttct agcctgatcg ggggagcatt tgcaggaatc gttgcacttc
     1321 aagcctttgc tttagtgggt cctgggattg caagtatcac gatgttcgct gacaaagctg
     1381 acccaatgaa tctggtttgg gcatttgcag tatcggggat ttcatttgtg gttgcttttg
     1441 ctgcagcgtt ggttctttat aaagataaag aagttgtcaa tgaagttgaa actaagatgg
     1501 aaacggccgt tgtttcagat gctgttcttt caagtcccgt gaatggaaaa gtaatctcac
     1561 tatcagaagt aaaagacact gttttttcta gtggtatggt aggtgatgga gtagcaatca
     1621 ttcctgaaga agggatatta gtagctcctg aagatggaga aatcacaatg gtatttgaaa
     1681 cgaagcatgc tattggttta aaaacggcta atggtgcaga acttcttttt catattggta
     1741 ttgatactgt tcagttagaa ggaaaagggt ttgaggcatt tgttcgttct ggtgaaaaag
     1801 tagccaaagg acaaaagctg attgcatttg atattgattt aatcaaagaa gcaggattcg
     1861 accccacagt tatctgtgtg gtaaccaata aggataatta cactatccgt tcatttaacc
     1921 tagaaaaatt ggtaaccaat gatagtgatc tcttagctat cagtccgata gcttaaacac
     1981 aagatagtga aaaaaaatat attgaatgaa ggaatagagg agaatagaat aatgacaaac
     2041 acaacaagtt ttccaaaagg atttttatgg ggcggcgcga tagcagcaaa tcaagtagaa
     2101 ggtgcttgga atgtagacgg taaaggtctt tcagtagcgg atatggctac ttataaacca
     2161 aatttagaca acaaagattt tgctgctcat atgcatgtca ccctgcagtc tataaaagaa
     2221 gctagtgaag acaaatctga taaatggtac ccaaaaagaa ggggcgttga tttttatcat
     2281 cactataaag aagatttagc tttatttgcc gaaatgggct ttaaaacctt gcgcctctct
     2341 attgcttgga ctcgcttgtt ccctacagga gaagagctgg aaccgaatga aaaaggggtt
     2401 gcattttatg aaaacgtctt taaagaaatg caacgtttag gaattgagcc gattgtgaca
     2461 ctatctcatt atgaaatgcc attagcttta gcagttaaat ataatggctg ggtggagcgt
     2521 cgagtaattg atgattttgt tcgcttcgct aacgtttgtt ttgatcgctt cggcaaatac
     2581 gtaaaatatt ggctgacatt taatgagata gacagcatcc accgtcatcc atttacaaca
     2641 gctggaatta tccaagagaa aagcgcagaa ggtcaagaag ctcaagatat ctatcaagca
     2701 ttgcatcatc aatttgttgc gagtgcgtta gtgacaaaag atgctcatga aaaaattcca
     2761 ggaagccaag ttggttgtat gttaacgaaa ttgatgactt atccattaac ttgcgcacca
     2821 gaagacgttg agctgacctt gaaaaagaac ttagaaaata atttttatgc agatgttcaa
     2881 gttaagggag aatatcctgc tctaatcgaa aaggatttgg aaaatcgggg aattcagatt
     2941 aaaatggaag atgaagatcg agaaatttta aagaaacata ccgtagattt tgtttctttc
     3001 agctattaca tgtccatggc agaatcagct gatccaaacg cagaacgcac accgggaaat
     3061 actgttttag gggttaagaa tcctcatttg ccttcaacag attggggctg gcaaatcgat
     3121 ccaaaaggtt tgaaaatttc gttgatcgaa ctttatgatc gttaccaagt accgttgatg
     3181 attgtggaaa atggtatggg agcagtcgat caggtagtag atggtaaaat ccatgatccg
     3241 taccgcatcg actactttaa agcacacttc caacaaatga aagaagcaat cgatgaaggt
     3301 gtagatttga tagcttatac tagctgggga ccaattgatt tagttagtgc aggaacttct
     3361 caaatgtcta aacgatatgg atttatttat gtggatgcag acgatgaagg aaatgggaca
     3421 tataaccgct tgaaaaagga ttcgttcaac tggtacaaag aagtgatcga aacaaacggt
     3481 gcatccttat tcgagtagtc tcgatctttt taagcagcga tagggggata atgagtgatt
     3541 tcaataaaaa aagtattgaa ttcaagtgtg gtacttgttg aagaaaatgg caaagaaatg
     3601 attgcattag gtaaagggat aggctttgga cagaaagctg gggatgaaat atcaggagat
     3661 aaagtagata aaatatttct gccttttgaa gaaaagaaat cttcacaact attagagtta
     3721 gttgaagaaa tacctattga attttttgaa atcactcgta ctatcgtttt tgaagcagaa
     3781 aaaggattag ataaaaaact gaatcctgga gtctatttaa ccttaacaga ccacctgcat
     3841 tttgcagttg aacgcgcaca aaaaggggta aatattgcaa accgtttgta ctgggaaata
     3901 aaaatctact atcccaaaga atttcaaatt gggaagtacg cactcaccct tttgaacgag
     3961 caatatggaa ttgatcttcc taaagaggaa gcctcaaaca ttgctttcca tttgatcaat
     4021 gcacaatcgg aagatcctga tagcggcgct ggattcaagt atgcaaaaat gatcggcggg
     4081 atcgtcaatt tggtccggta ttcgttgcag aaagatatcg atactaattc gatccattat
     4141 gcccgcttca ttacacatgt acgtttcttt gtagaaagat attattctga tgctttgttg
     4201 gatgatggtg aggaagaatt ctacaatcaa atgtggatct tatacccgtc tgccatggaa
     4261 agcgcagcta agatcaaaga ctacattgaa aaagtttatc ataaaacaat tccgaacgat
     4321 gaagttgtat acctaggtgt ccacatcaat cggttgatga aacatgctaa tgggtgagcg
     4381 ctcagtaata ctattgatgc ttttaaaatc tttagagatg gattatagta aaaacaaggt
     4441 gatttccagc tgtttgttat ctataagaga catttaaaaa ggattaacgt aagataataa
     4501 aaaatct
//
LOCUS       DAFBSV010000127         4447 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.132, whole genome shotgun sequence.
ACCESSION   DAFBSV010000127 DAFBSV010000000
VERSION     DAFBSV010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4447
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.132"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(462..887)
                     /locus_tag="LLB18_002640"
     CDS             complement(462..887)
                     /locus_tag="LLB18_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245598.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            1261..2232
                     /locus_tag="LLB18_002641"
     CDS             1261..2232
                     /locus_tag="LLB18_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5245599.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            2264..3661
                     /locus_tag="LLB18_002642"
     CDS             2264..3661
                     /locus_tag="LLB18_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBK5245600.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            3820..4443
                     /locus_tag="LLB18_002643"
     CDS             3820..4443
                     /locus_tag="LLB18_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245601.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
BASE COUNT         1559 a          714 c          904 g         1270 t
ORIGIN      
        1 aaaaattact acgtgatgta gaataagcct ttctatcgtt tggttatttt atattcaaat
       61 atttgaaata aataaatctt tactctttga tttgtaaact gaaatgatcc actgtttgtt
      121 ttactgatga agcttgatca aaggaagaag ctgagtttga agttcataaa aatcagccat
      181 agtgagtttt gcttggattt gtttatcttc ttctactttt tacataattt tgaacaggat
      241 aagattcaaa tgttttaaat gaatctttga ctagtttgtg acagttgtcg catatgctca
      301 agcttccttg gtcattaaat tctgtatgga tatttttgtt gttattacat gtacaataat
      361 caggactatc gatcatccat ttcgtctcct ttacaatcat cttgcttctt tactatagca
      421 gaaaagaagg ggagaaacaa aagaagatcc aacagacggc actatagact gtagatgttg
      481 ccatcctcat ccttcaaacg gtaattaccg atttttgtaa atatgactgt tgtttctttt
      541 ttattttctt ttcctgaaat aatatattcg tcatctttgg tagtgatctt gatatctgtc
      601 agcactgttt tttcttcaga tgattcagaa gaatcagttc cttgtgtctg atacgtgcgt
      661 gtccattcca tttttttatc tgtaaatgtc aactgtcccg cggataaatc catatcttta
      721 cgtactttta gcgtatatac actgttggtg gtatctgctt tttccgcttt taagacagaa
      781 gaatcggttg tttcgtccga ggattggtca gagccgccaa acaaatcaca gccagtcaat
      841 gtcaaaagtc ccgcagacaa aataaatagt acgattaatt tcttcaaaat acttccccca
      901 tttgatagga taaagaaatt ataccattgg aatgtaaaac ttcaaacgga tggaagagaa
      961 aaacgcacaa aacacccaca aatagagtaa attttagaat aaaattttaa aaaggcaaaa
     1021 aatccgccac tttcagaaag cgttttaaaa aagtgttgca atcttttaaa aaaatgctat
     1081 attaaaaatg aaccggttca aatacttgtt taagtataat taatagtgag aggaagttgc
     1141 tctactgaag actttagtta tatggatatt gatgacaagc aacactatgc aaagaatgcg
     1201 gtcatcataa tcgaacaaca agaaagagaa atcaaatgta actggcagga gtgagaatgt
     1261 atggcatcga tccgtgatgt ggctaagatg gctggtgttt cagtgggaac agtttcccgt
     1321 tacttgaatg gtcagcaact gaaggaaaag aacatgaaaa aaatagcaga agcgatttca
     1381 gcgttggact ataaagaaaa catcattgct aaagggttga agaataatcg aagcttctct
     1441 attggacttt tgataaacgg gatttccagc cgttttgggt cggaagttgt ctcagggatc
     1501 gaaagagtag ctgaagaaaa tgggtatagc ttattattaa gcgggtttgc cgatcagcca
     1561 gaaaaaattg aacaaaaaat tgaatacctg atgaagcatg tgatcgatgg gctgattgtc
     1621 ttcttatccg aagaagagtg gtctggattt gaaatgctca caaaaatgag tattccagtt
     1681 atcgcattga attgtccaga aggaccagca ggtattgata caatattagt gaatgatcga
     1741 gaaagtgtag caaaagtgat cgctcatcat ggtgaacaag gacataaaaa aatcggattt
     1801 attgctgcca ctcaaacaga ctacgtagca agagaacgtt tagcaggagc caaagaagcg
     1861 gtccaaaatg atccatcgat ccaattagag gtctttacag gagactattc tagaaaaagc
     1921 ggctattacg gggcaaaagc attattagaa aaaggggcaa ctgctatttt tgtcagcaat
     1981 tacaatatgt cgattggtgc catcgaatgt ttcaatcaag aaggtgtcag aatcgggaag
     2041 gatattgcgt tcagtcacta tgattattta gataaaaacg atctgagtat ccttccgaaa
     2101 atcacgatca cgccaccaac agataaaatc ggggaacgag cagcagaaca gctgttaaaa
     2161 cgaatcaaaa aagaagagga agaaaatgaa aaagtgattg tgatggaaaa tatcatacat
     2221 ggaatcaact aaaacgaact aaaaaagaaa aagaggtgct ttgatgaaaa aatatcaatt
     2281 tccagcaaat ttttggtggg gttctgcagc aagtggccca caaacagaag gaaggatttc
     2341 aggcgatgga aaaggagaga acatttttga ttattggtac aaaaaagaac cgcaaaagtt
     2401 ctttgatcaa gtaggacctg aaaaaacctc gcaagtttat acgaagtatc aagaggatgt
     2461 acagttgatg aaacagactg ggcataattc atttcgaaca tctatccaat ggagccgttt
     2521 gatacctgat gaatctggaa caatcaacga agaagccgtt cgtttctatc atcgttattt
     2581 tgatgagttg attgaaaacg gtatcgaacc ctttgtgaat ctgtatcatt tcgatatgcc
     2641 gatgtatctg caagaaaaag gcggatggtt gaaccgagaa acggttgaag cctatgaaaa
     2701 atatgccaaa agttgttttg aattgtttgg ttcgaaagta aaaaaatggt ttactcataa
     2761 tgaaccaatc gttccagtcg aagcaggtta tttatatcga tggcattatc cagaagagtc
     2821 agatatgaaa aaagcgatcc aagttggcta tcatgaagcg ttggcttcag cgttagccat
     2881 caaatcttac catgaaatgg agcaaggtgg tgttattggt atcatcttga atctgacacc
     2941 aagctatcca agagacgaat caaaccctga agatgttaaa gcagcgcaaa tagcagatgc
     3001 gttcttcaat cgttcattcc ttgatccagc tgtaaaaggc gagtttccaa gtgaattgat
     3061 tgagatagta aaagaacttg atctcatgcc tgtgatccat gcagaggatt tgacggttat
     3121 caaagaaaat acagtagatc ttttaggtat caattattac cagccacgcc gggtaaaagc
     3181 aaaagaaaca ccaatcgata ctaaaaacgg tccaatgcct gaggattatt tcgacaatta
     3241 tgaaatgcct ggtcgtaaaa tgaatcctta tcgcggatgg gagatctatg aacaaggaat
     3301 ctatgatatt ttgatcaatg tacgagatca ttatggaaat atcgactgct ttatttctga
     3361 aaacggtatg ggtgtagaaa acgaagcacg atttatcaaa gaagatggca tgatccacga
     3421 tgattatcgg atcgaatttg tccaatctca tctgaaatat gtccatcaag ccattcaaga
     3481 aggtgccaat tgtttaggct atcatatgtg gacatgtatg gataactggt cgtggaccaa
     3541 tgcatataag aatcgatatg gctttatttc agtagactta gcacaagatg gaaaaagaac
     3601 aatcaaaaaa tcgggtcatt ggttcaaaga cgtatcagat aaaaacggat ttgaggctta
     3661 agaaagaata gttgagagca aatgcgtgaa attctccatt cttaccattt tgtgaaaaag
     3721 aagttcaatt atttacgatc tttttcaact tttttgtctt tctatttcat tttttgtata
     3781 taatagaata gtcaaaatta aataggagtg gaggaaagca tgaggaaaaa aagaccgttt
     3841 cttctctttt ggttattcgg ttttttctta ctgcttattt tatccgcagc attttcagga
     3901 aaaatgacag cagatcttgc tcagaaagaa acagaaaaaa tcgtagcaag caaagaatca
     3961 gtagataatt tcaaaaaaga attctcaact tattggtggg cggagtataa aataactgcc
     4021 aattacgaaa aaggcgaatt ggacatttat ttgccaaaag gaaaagaaga aaatcaattt
     4081 attaatatcg atgacgtact tagtgcgatt tctctcagac aatatcaatt taaagacaag
     4141 catttgaccg ttttgctttt gactcatgat ggcgacaaag tagcccgttt gaaaaatgga
     4201 aaagtgatca ccgcttattc tgaaaaagta gacaaaaaag tggtcgccga tcgtttagcg
     4261 gaatggaaaa agacaaatga acaagtcaag aaaacaactg tctcttctca aaaaaacgag
     4321 tcgacaggaa caagtccttc agattctggc agtggacaaa cgataacggg aagtgaagaa
     4381 aatcaagcct caattattac gaatgagtca tcacaaggac aatatcaatc ctatggacaa
     4441 tgaaaaa
//
LOCUS       DAFBSV010000128         4430 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.133, whole genome shotgun sequence.
ACCESSION   DAFBSV010000128 DAFBSV010000000
VERSION     DAFBSV010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.133"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(543..2048)
                     /locus_tag="LLB18_002644"
     CDS             complement(543..2048)
                     /locus_tag="LLB18_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK5245602.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="LLB18_002645"
     CDS             complement(2045..2731)
                     /locus_tag="LLB18_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5245603.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="LLB18_002646"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="LLB18_002646"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HBK5245604.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1238 a          919 c          729 g         1544 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat
//
LOCUS       DAFBSV010000129         4305 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.134, whole genome shotgun sequence.
ACCESSION   DAFBSV010000129 DAFBSV010000000
VERSION     DAFBSV010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4305
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.134"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            148..1137
                     /locus_tag="LLB18_002647"
     CDS             148..1137
                     /locus_tag="LLB18_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HBK5245605.1"
                     /translation="MKKKKQDLINGTFREKKKNLKKVVAFSDNRISPKMRELMTGCGS
                     YLEFIATIDKEKKKLVQAHFCKNRFCPLCAWRKARKDSMMLSIMMQAIAEEKQYQFIF
                     MTLTTPNVKAECLNDEIDLFNHALKKMFMRKRVKTSIKGYVRKLEITYNKKRNDYNPH
                     FHLILAVNKSYFTDKDYYIKQSEWLDLWREVTGKTGINPDGTDEITQLDIRKVKGFQQ
                     EKAVQEVAKYSAKDFELTESQEVFDTFYHAMKGRQLITFNGVFKEYKKKYESGDLDRY
                     KKKDENEYFWFLTASWMRKESKYAVDYREMSADERNYFSGMYVDEKSVEGENE"
     gene            1134..1553
                     /locus_tag="LLB18_002648"
     CDS             1134..1553
                     /locus_tag="LLB18_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245606.1"
                     /translation="MTDSTDKMTIKALADELGITKNTVRNYLVKAGYDLARYKKNGII
                     LLDKELIGVARSIYRSKGGQLTGHLPVNSTGSDFPLEKENEFLRDQLAEKDKHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            1532..1870
                     /locus_tag="LLB18_002649"
     CDS             1532..1870
                     /locus_tag="LLB18_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245607.1"
                     /translation="MVAILEVRCDMDKIDLREETVNRIEVMYERLADYLNLSDEDNYS
                     EMLERMMDVLNSVINADLAKSSVLTNEFVHKHLAQTTDEAEKEFWLKLMSHIMQLNQI
                     SVINSKEKGM"
     gene            1874..2236
                     /locus_tag="LLB18_002650"
     CDS             1874..2236
                     /locus_tag="LLB18_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245608.1"
                     /translation="MGMTLADIKVQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFESFADFERWLSSISDDQQHEKSVGNELRADEKSAPSERNYPNESDGIFGGIPNRK
                     SQMSESGFASMFSDVNSR"
     gene            2458..3864
                     /locus_tag="LLB18_002651"
     CDS             2458..3864
                     /locus_tag="LLB18_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HBK5245609.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDSQKINDWHKHIDFTKSDEN
                     IYLEQINIREKYEELFGEAVEKYNAKQKRADRKIEDYLAKVRKDKKMEPQREFIVQIG
                     TLDDFRTTRDDGSSTGISEQQAEQNRVIANKILVEYFKEFKERNPSLSVYNAVIHNDE
                     VSPHLHLNIVPVAEGYKRGVQKQPSFNKALQQQGLRADKENGRVIWNNFRNQEVESIE
                     RLMADFGWERELVGTNKIKDIHEYKEIMSEISELRQTAVKERESVSDELRYICRQREE
                     NEREKALVASERAKIEEEKKNMLNVKKEMAVIFQKDMVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVAALEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQHKLERSEDEIEW"
BASE COUNT         1497 a          602 c          996 g         1210 t
ORIGIN      
        1 aaaaaaaaag attgcttttt cttccctagt attttatagt tttaattgac tagaaaaaaa
       61 ctaaactaga aaggagagca atctattttt tgttatcggc ttttcagcct tttttgtata
      121 caaaatttgt agattcagta tagcaagatg aaaaagaaaa agcaagattt gattaacgga
      181 acatttcgag aaaaaaagaa aaatttgaaa aaagtggtgg catttagtga taatcgaatt
      241 tctcccaaaa tgcgtgaatt gatgacaggc tgtggttcat atttagaatt tattgcaacg
      301 attgataagg agaaaaagaa attggtccaa gctcactttt gtaaaaatcg tttctgtccg
      361 ttatgtgctt ggcgtaaagc tcgtaaggat tcgatgatgt tgtcgattat gatgcaagct
      421 attgcggaag aaaagcagta tcaatttatt tttatgacgt tgacgacacc gaatgtaaaa
      481 gcggaatgtt tgaacgatga aattgatttg tttaatcatg cattgaaaaa gatgtttatg
      541 cgcaaacggg ttaagacttc gattaaaggc tatgtgcgaa aattggaaat cacgtacaac
      601 aaaaaacgga atgactataa cccgcatttt cacttgattt tggcagtaaa taaatcttat
      661 ttcacggata aagattatta tatcaagcaa tcggaatggt tagatttgtg gcgggaagtg
      721 accggaaaaa cgggaattaa tccggatggt accgacgaaa ttacccagtt ggatattcgc
      781 aaggtcaaag ggttccaaca agaaaaagca gtacaggaag ttgcgaaata ttcggcaaaa
      841 gattttgaac tgaccgaaag tcaggaagtg tttgacacat tctatcatgc aatgaaaggt
      901 cgtcagttga ttacgtttaa cggtgtattc aaagaataca agaaaaaata tgagtcgggt
      961 gaccttgatc gttataagaa aaaagatgag aatgaatatt tttggttttt gactgcttcg
     1021 tggatgagga aagaatcgaa atatgcggtt gattatcgtg agatgagtgc tgatgaaaga
     1081 aattattttt caggaatgta tgtcgatgaa aaatctgttg agggggaaaa tgaatgactg
     1141 attcaacgga taaaatgaca attaaggcgc ttgctgatga actaggaata accaaaaata
     1201 cagtgagaaa ttatctagtc aaagccggat atgatcttgc tcggtacaag aaaaatggaa
     1261 ttatcttgct agacaaagag ttgattggtg ttgctcggtc aatttatcgg tcaaaaggtg
     1321 gtcaattgac tggtcattta ccggtcaata gcacgggcag tgattttcct ttggaaaaag
     1381 agaatgagtt tttgcgtgat caattagctg agaaggacaa acatatttct gaattaacag
     1441 aaatgattcg tgatcaacaa aaattgaccc tgcttcagca acaaaaaaac gatcagttgt
     1501 tactagaaaa tcaagaatta aaaaatcgaa aatggtggca attctggaag tgagatgtga
     1561 catggataaa attgatttga gagaagaaac agtcaataga attgaagtga tgtatgaacg
     1621 gttagctgat tatttgaatc tttcggatga agataattat agtgagatgc ttgaacgaat
     1681 gatggatgtt ctcaactcgg ttatcaatgc tgatctagca aaatcttcag ttttgactaa
     1741 tgaatttgtt cataagcatt tagcgcaaac aactgatgaa gctgaaaaag aattttggtt
     1801 gaaattaatg agtcatatta tgcagttaaa ccaaatttcc gttattaatt ccaaagaaaa
     1861 ggggatgtag tttatgggaa tgactttagc agatattaaa gtgcaagaag aaaaattaaa
     1921 aaaagaacag gcgaaacttc gccaacagaa gaaacgattg attgagaaag aaaatgctgc
     1981 aatgggcaag gctcttcgca agcgttttgg gtttgaatct tttgctgatt ttgagcggtg
     2041 gctatcgtcg atttctgacg atcagcaaca cgaaaaatca gtgggtaatg agttgcgagc
     2101 tgatgaaaaa tcagcaccaa gcgaacggaa ttaccctaac gaatctgacg gaatattcgg
     2161 agggataccg aatagaaaaa gtcagatgag tgagagtgga tttgcgtcaa tgtttagtga
     2221 cgtaaattca cgataagcga atattttgca tgaagcaaaa taaagcgtaa aaggagttga
     2281 gagcgtgaca cgctttcggc tccttttttc gttgtcactt gtgacggcga aaaccctcgg
     2341 agagcgtttg gaattgtgac agtcatgtca caattaggaa aacgttactc tttgacaaag
     2401 agtaacagaa aggtttacac tctttttatt agcgacagcg cgaaggaggg gtttaacttg
     2461 gggtttagta tttcgttcaa aaagggaaca aagaatacaa gcatttctca taataatcgt
     2521 gagttaactg atagccaaaa aatcaatgac tggcataagc atattgattt cacaaaatcg
     2581 gatgaaaata tctatttgga acaaataaat attcgtgaaa aatatgaaga attattcggt
     2641 gaagccgtag aaaaatataa tgcaaagcag aaaagagccg atagaaaaat tgaggactat
     2701 ttagcaaagg ttcgcaagga taaaaaaatg gaaccacagc gagaatttat cgtgcaaatt
     2761 ggtactcttg atgattttcg tactactcgt gatgatggtt cttctactgg catatcggaa
     2821 caacaagcag aacaaaatcg agtgattgcc aacaaaattt tagttgagta tttcaaagaa
     2881 tttaaagaac ggaatcctag tttatccgtc tacaatgctg ttattcataa tgacgaagta
     2941 agtccgcacc tgcatttgaa tattgttcct gttgctgaag ggtataaacg gggtgttcaa
     3001 aagcaaccaa gttttaacaa agccttgcaa cagcagggtt tacgagcaga taaagagaat
     3061 ggtcgagtga tttggaataa ttttaggaat caggaagttg agtcaattga acgtttgatg
     3121 gcagattttg gttgggagcg tgagttagtc ggtactaaca aaatcaaaga tattcatgaa
     3181 tacaaagaaa tcatgagcga aatttccgaa ttgcgtcaaa cggccgtaaa agagcgtgag
     3241 agcgtttctg atgagttgag gtatatttgt aggcaaagag aagaaaacga gcgtgagaag
     3301 gctctggtgg cttctgagag agcgaagatt gaagaagaga agaaaaatat gctgaatgta
     3361 aaaaaagaga tggcggtcat tttccaaaaa gatatggttc ctttagaaag tttcaagagg
     3421 cttcctgatg gttcgtatca tttatctggg aatgattttg ttgatttgta tcaacgagct
     3481 acgagagcaa caaatgccaa gagaaatgct gataacatga gtgagcaata tttacagatg
     3541 cttgagcaaa atacagaatt aaatgagtat gtagctgcat tggaagaaga gcgtcatttg
     3601 tctggtagaa aacaattagc agatttacaa gtggaaaata aaaagctgaa agaagaaaat
     3661 cgctctttac gccagcgttt agagcgatta aaaaacgcat ttcaaaaatc gatcactcgt
     3721 ttgtctatcc gttttgggct tgcagaaaag gatatggggc tttctgagga attagaagta
     3781 ttagagcagg agaaaacctt attttatcgt caaaacgtct cacagcataa attagagcgt
     3841 tctgaagatg agatcgagtg gtagttacga tgtgcagtca acggtaccgg aggcggtttg
     3901 tgccgaggat aaggagttga cggctaaacc actagcctat taagctgaca tttgctaaaa
     3961 aatggcaagt ccattttttg gccaacttag cgttagcgaa gtttgggggc gcccttttta
     4021 aagggtgcgg ttttatgttt gcatgactaa gaatgagtgg gaaaatttaa cagccctatc
     4081 taacaggcgg ttaaatgtac aaaatatgta caccccctta aaaatgcagt ggtcgattga
     4141 tcgaatttta tgtctttggg ttttggggtt ttaaaacgaa aaaaaggggg cgattttcgc
     4201 cctctttttt gatgtttttt cttatcttga tactataggc aactatttct gcgaagaaat
     4261 cggggctata gtatgggtct atcccttgtg gctctaagga agaac
//
LOCUS       DAFBSV010000130         4078 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.136, whole genome shotgun sequence.
ACCESSION   DAFBSV010000130 DAFBSV010000000
VERSION     DAFBSV010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4078
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.136"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(<1..264)
                     /locus_tag="LLB18_002652"
     CDS             complement(<1..264)
                     /locus_tag="LLB18_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBK5245610.1"
                     /translation="MSKKGTIINEWEKLTAPSNRRLSVPFMDTPLKIQWSIDRITIVG
                     NLKENIYYHTTHDVLILDFEQLMRLNEGNGYLRSVSNNGWQLLD"
     gene            complement(713..2128)
                     /locus_tag="LLB18_002653"
     CDS             complement(713..2128)
                     /locus_tag="LLB18_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HBK5245611.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDSQKTNDWHKHIDFTKSDEN
                     IYLEQTNLADKYEELFGEVVEKYNAKQKRADRKIEDYLAKVRKDKKLEPQREFIVQIG
                     ILDDFQTNRADGSSTGISKQQAEQNRVIANKILVQYYKEFQERNPNLAVYNAVIHNDE
                     ISPHLHLNIVPVAEGYKRGVQKQPSFNKALVQQGIHADKDNGRVLFNNFRNQEVDSIE
                     RLMNDYGWKRDIVGTNKIKDIHEYKEIMSEISELRQTAVKERESISAEMRYISKQREK
                     NEREKALVASEKAKIEEEKKSIIDLEKELAVVFQKDPVPLNSFEKLSDGSYRLSSADF
                     VDLYQKASNATNSKKYADMANESLGNTLDKNIALFDKNMALEQENSFLKNQQKVDVSA
                     VVAENKKLKEENRSLRRRLTQLKNAFQKSITRLSIRFGLVEKDMGISEELKILDQEKT
                     LASQQNAPERNIGRSENEMEW"
     gene            complement(2350..2712)
                     /locus_tag="LLB18_002654"
     CDS             complement(2350..2712)
                     /locus_tag="LLB18_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245612.1"
                     /translation="MGMTLADIKAQEEKLKKEQAKLRQQKKRLIEKENAEMGKALRKH
                     FGFESFDDFERWLSSISDDQQHEKSVDNEWLADEKSAPSERDYPNESDGLLGVIPSKK
                     SQMSESKFTSMFNDVSLR"
     gene            complement(2716..3063)
                     /locus_tag="LLB18_002655"
     CDS             complement(2716..3063)
                     /locus_tag="LLB18_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245613.1"
                     /translation="MVAVLEMRCNMDKIDLREETVDRIELMYERLADYLNLPDEDNYS
                     EMLERMMDVLNSTINVGLANSSLITDKFVYGKIAETEDESEKEFWLNILTYVMQLNQI
                     GVIYRNKSKGKEL"
     gene            complement(3134..3367)
                     /locus_tag="LLB18_002656"
     CDS             complement(3134..3367)
                     /locus_tag="LLB18_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245614.1"
                     /translation="MTEKQKYFGKKNWLVNLTGDYVVVVFLDSKKMSGKLLDVTQYEL
                     ILKNNKIDSPIIIPKHAVKYIYAVAESSGEAND"
     gene            complement(3364..>4078)
                     /locus_tag="LLB18_002657"
     CDS             complement(3364..>4078)
                     /locus_tag="LLB18_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBK5245615.1"
                     /translation="DQHEENIAYIEILKWQEGKGRIDFNPNKISQFLASSMKNFIHDL
                     FIEPHFSRADIACDIIDVPDEFITQYRVVDPVSFKPIYGRNGKLETAYWGSRSSERQI
                     RMYNKKLEQEKKRKIVPKEIVSWWRLELQLRRGKATDWHAMVYESLDSFASPHYLPAD
                     TSVADKMMITALTTEHDYWGQINRKTKYKYRNLLKQESQNDELTNHLRETFAESADDL
                     KKELDTWLLGLDVTEEEEK"
BASE COUNT         1153 a          897 c          577 g         1451 t
ORIGIN      
        1 gtctaacaac tgccaaccat tattactaac agatcttaaa taaccgttac cttcatttag
       61 gcgcataagc tgttcaaaat ctaaaatcaa cacatcatgt gtagtgtgat aatagatatt
      121 ctctttaaga tttccaacaa tggtaattcg gtcgattgac cactgaattt ttaggggggt
      181 gtccataaaa gggacactta accgcctgtt agagggggct gttaattttt cccactcatt
      241 tatgatcgtg ccttttttac tcaaatttag ttcctcctca aagaaaaaag agattggtgg
      301 aaagaatttt ccagagttca cgtaactcta aaaaattcat aaccagcaat ctctagtctt
      361 gaagaaacct gaaattattc gtataatgaa tttgagttac ggagctagtg tgattagttt
      421 ccgtaaaggt cgagaacgtg tccagcgttg ctcgacttta tttttttgct cttttttcag
      481 tttatttatt tgataactca ataatagcac ttctctttag ctatgcaaat atccaaaaac
      541 ataaaaccgc accctttgaa aagggcgccc ccaaacttcg ctaacgctaa gttggccaaa
      601 aaatggactt gccatttttt agcaaatgtc agcttcaggg attagtggtt tagccgtcaa
      661 ctccttatcc tcggcacaga ccgcctccgg taccgttgac tgcaccgtat aactaccact
      721 ccatctcatt ctcagaacgc cctatattac gttctggggc attctgctga ctagccaacg
      781 ttttctcttg atctaatatt tttagctctt cagatattcc catatctttt tctacaagcc
      841 caaaacgaat tgataaacga gtgattgatt tttgaaatgc gtttttcagt tgagttaacc
      901 gccgacgcaa agaacgattt tcttccttca gctttttgtt ttcagcaaca accgctgaca
      961 catcaacctt ttgttgattt ttcaaaaaag aattttcttg ttctaacgcc atgtttttat
     1021 caaataaagc gatattttta tctaatgtat ttccaagcga ttcattcgcc atatcagcat
     1081 attttttgct gttcgtagca ttagacgctt tttgatacaa atctacaaaa tcagcactag
     1141 ataagcgata agaaccatct gataattttt caaaactatt gagtggcaca ggatcttttt
     1201 gaaatacaac agccagctct ttttccaaat cgataatcga ttttttctct tcttcaattt
     1261 tcgccttctc agaagccacc agagccttct cacgctcgtt tttttctctt tgcttagaaa
     1321 tatacctcat ttccgcagaa atgctctcac gctcttttac agccgtttgg cgcaattcag
     1381 aaatttcact catgatttct ttgtattcgt gaatatcttt aattttgttg gtaccgacaa
     1441 tatccctttt ccaaccgtaa tcattcatta atcgttctat agagtcaact tcttgatttc
     1501 taaaattatt gaaaagcact cgaccattat ctttatcagc gtgtatccct tgttgaacca
     1561 gtgctttatt aaagctcggc tgcttttgaa caccccgttt ataaccttca gcaaccggca
     1621 caatattcaa gtgcaggtgc ggacttattt cgtcattatg aataacagca ttataaacag
     1681 ccaaattagg gtttctctct tgaaactcct tgtaatactg aaccaaaatt ttattggcaa
     1741 tcactcgatt ttgttcagct tgttgtttcg atatgccagt agaagaacca tctgctcgat
     1801 ttgtctggaa atcatctaaa atgcctattt gcacaataaa ttctcgttga ggttccaact
     1861 ttttatcctt gcgcactttc gctaaatagt cctcgatttt tctatcggct cttttttgtt
     1921 tcgcattata tttttctacc acttcgccaa acaattcctc atatttatct gctagattcg
     1981 tctgctctaa ataaatattt tcatccgatt tcgtgaagtc aatatgctta tgccaatcat
     2041 tggttttctg gctatcagtt aactcacgat tattatgaga aatacttgta ttcttcgttc
     2101 cttttttaaa tgaaatacta aaccccaagt taaaaccctc cttcgcgctg tcgctaataa
     2161 aaagagtgta aacctttctg ttactctttg tcaaagagta atattttcct aattgtgaca
     2221 tggctgtcac aattccaaat gctctccgag ggtattcgct gtcacaagtg acaacgaaaa
     2281 aaggagccga aagcgtgtca cgctctcaac tccttttacg ctttattttg cttcacgcaa
     2341 aataatcgct tatcgtaaac tcacgtcatt aaacattgac gtaaatttac tctcactcat
     2401 ctgacttttt ttactcggta tcactccgag taagccgtca gattcattgg gataatctcg
     2461 ttcgcttggc gctgattttt catcagcaag ccactcatta tccactgatt tttcgtgttg
     2521 ctgatcgtca gaaattgacg ataaccaccg ctcaaaatca tcaaaagatt caaatccaaa
     2581 atgcttccga agtgccttac ccatttcagc attttccttc tcaatcaatc gttttttctg
     2641 ttgacgaagt tttgcctgtt cttttttcaa tttttcttct tgtgctttaa tatctgctaa
     2701 agtcattccc aagatttaca gctccttgcc ttttgattta tttcgataaa taacaccaat
     2761 ttgatttaat tgcataacat aagttaaaat attcagccaa aattcctttt cagattcatc
     2821 ttctgtttcg gctattttac cgtaaacaaa tttatcagta atcaaagaag aatttgctag
     2881 gcctacattg attgtagaat tgagaacgtc catcattctc tcaagcattt cactataatt
     2941 atcttcatcc ggcaaattca aataatcagc taatcgttca tacatcaatt caattctatc
     3001 aactgtctct tctcttaaat caattttatc catgttacac ctcatttcca aaactgccac
     3061 catttccgat tctttaattt tcgatacacc taattcatca gcaagatttt ttatggtcat
     3121 cttttctgac aaatcagtca ttagcttctc cactactttc agctaccgca taaatatatt
     3181 taacggcgtg cttagggata ataatcggag agtcaatttt attatttttc aaaatcaatt
     3241 catattgcgt tacatcaagt aacttaccgg acattttttt gctatccaaa aaaacaacca
     3301 caacgtaatc acctgttaaa tttaccaacc aatttttctt accaaaatac ttttgttttt
     3361 ctgtcatttt tcttcctcct ctgttacgtc tagccctaga agccatgtgt ctaattcttt
     3421 ttttaaatcg tctgccgatt ctgcaaaggt ttctcgtaaa tgattcgtca attcatcatt
     3481 ttgactttct tgcttcagca aattccgata tttatatttt gtctttcgat taatttgccc
     3541 ccaataatca tgttctgttg ttaaagcagt aatcatcatt ttgtcagcta cacttgtatc
     3601 agcaggcaag taatgaggac tagcaaaact atctaagctt tcataaacca tagcatgcca
     3661 atcagtcgct ttccctcgtc ttaattgtaa ttctaaccgc caccaactca cgatttcttt
     3721 tggcacaatt tttcttttct tctcttgttc cagtttttta ttatacatcc gaatttgacg
     3781 ttcagaagag cgagatcccc aatatgccgt ctctaatttt ccattccgtc cataaatagg
     3841 cttaaaagaa actggatcaa ctacccgata ttgtgtaata aactcatcag gtacatcgat
     3901 aatgtcgcaa gcaatatctg cacgtgaaaa gtgaggttcg ataaacaaat catgaataaa
     3961 atttttcatg gaactagcta agaattgact aatcttattc ggattgaagt ctatacgccc
     4021 tttcccctct tgccatttta aaatttcaat ataagcaata ttctcttcat gttggtct
//
LOCUS       DAFBSV010000131         3850 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.137, whole genome shotgun sequence.
ACCESSION   DAFBSV010000131 DAFBSV010000000
VERSION     DAFBSV010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3850
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.137"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(45..1364)
                     /locus_tag="LLB18_002658"
     CDS             complement(45..1364)
                     /locus_tag="LLB18_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK5245616.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1361..2014)
                     /locus_tag="LLB18_002659"
     CDS             complement(1361..2014)
                     /locus_tag="LLB18_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5245617.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2302..2822
                     /locus_tag="LLB18_002660"
                     /pseudo
     CDS             2302..2822
                     /locus_tag="LLB18_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2724..3440)
                     /locus_tag="LLB18_002661"
     CDS             complement(2724..3440)
                     /locus_tag="LLB18_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBK5245618.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(3490..3699)
                     /locus_tag="LLB18_002662"
     CDS             complement(3490..3699)
                     /locus_tag="LLB18_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245619.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
BASE COUNT         1238 a          727 c          480 g         1405 t
ORIGIN      
        1 ataagtctct atttttcaat aactattgca aaattatatc ttaattaaga aaatattttt
       61 attttaaaga taaaaaattc ttcatcctgc aatactttat attctatatt gtaattattc
      121 agaatattac ttacaatata taaacctaat ccattactat tttccttatt taaatcaaat
      181 ttaacatcaa atattttatc catattcgaa attttattgt taccgtatga attctctata
      241 tataaccaat cattaactat cccaatatta attaccccat ttacatcagt atattttacc
      301 gcattactaa tcaaattaga tagaataatc tttaaagctg tttttcctat ataaacattc
      361 tcgtctaata tataattatt gacagttatt ttcttttgat ttgctaatat ttcatacttt
      421 tttaatatgt cttctaatgt atcatttatt ttcaaatatt cttcatcatt attcaaattt
      481 tctatagaat gaactgataa tatttgagaa atattttttg ttaaactatc aacgatttca
      541 atacattcat taatataaat atctctttct ttatattttc caatattgta tttcatgttt
      601 tccagtatta ttttaagact agcaagaggg gttttaagtt catgggatgc acctttaaaa
      661 aagtcatatt ttaacttttc taattttaaa atttctttat ttttaaattc caaatcgtca
      721 attgttctta ataaagtaga atacaaatca ttaatttgtt gttttaattc tccaacttca
      781 tcattagagc taacttttaa actcattttt ttatcaagtt tcatcatttt atcagtaaca
      841 atttttattt cttgtatatt attttttatt gattttgcat aaattaaaga aataatagca
      901 gaaaataaaa ttgatattaa taaagaatat ggtaaaaatt taaggcttaa atctttcgca
      961 tctttttgca tatcagctgt agaaacaaat tgtagatttg tttttttacc atcattaagc
     1021 tttatttctc tttcttcaat tatcaaagaa ttactatcac tttctaaatt aacatttata
     1081 ttatctttga tttgtatttc attcttatta tttttttctt ttatgaatac ttttatttca
     1141 ctactcttgg aataaaactc caaagtttgt tctatatatt ttatttcttt tccattcata
     1201 ttactagaaa tttcatttgc catattatga atcttttctt ttctcgtctc caaatatgtt
     1261 ttaggaaaga taaaaaaaat taatgaatga actaatataa ttattattcc aagaacagaa
     1321 aatatttgta tgaacatttt tggaaatatc tttaattttt tcattttctc tccaatttat
     1381 atcctacatt tcttatagta gttatacagt ctaattgtaa tttttttcta agttctttta
     1441 tatatacatc tattactcga tcataaggag tttcttcgct atctttccat acataatcaa
     1501 taatttgcat tcttgttaac acttgtccat tattatccaa taaacatttt aatacttcta
     1561 gttcttttgc atttacatct atttcttcac catttatttt agctgtatag ctattaaaat
     1621 taaccgatag atccttatat tcaaacttct ctaaatgtcc ataattcttc ttaattaaag
     1681 aatctattct agcttttaag accggcaatg aaaatggctt ttctacatat ccgtctacta
     1741 aattagtaaa tgcatcaatt ttatattctt catcactaaa tgcagtcaag attagaattg
     1801 gtaaattgct tttctttcta atttctttca acacttctaa accatttata aaaggtatct
     1861 gaatgtctaa gataaccaaa tttatatcgc tattaaattt tgacaaggct tctcttccat
     1921 ctttagcttg aataacagta tatccaaatt ctgaaagata ttcacttatt ccctctctta
     1981 tcatattatc atcttcaaca gttaatattt tcatatatac ctccacttaa gcctatacac
     2041 tagatattat acagcatatt atggctctat aatatctagt gttggtgacg ccttctgttg
     2101 ccaatacttt ttcttttttt taataaatgc aaacagacac cttgaaatcc tttagaaaaa
     2161 aggcttctat aatattttgt gttgttggaa aatcgaaggc gattttctac taacactttt
     2221 tcttcgtttc aactcaaaaa gagactcact tttggtaaaa tttagtcgac caaaacatca
     2281 ccctaccaaa ggagtcgctc tatggataat catactagaa aattactcgg attaacagat
     2341 aaacatttat tttttgatga agaatggctg attgaaaaag aatataaagg cgttcaagcg
     2401 cagtttatta aagggagatt ggatgactca ccttcccatt gtgaacactg tggatcgatt
     2461 cgtattatcc gcaacggttc ctatacgaca cgtactcaga tgttgaaagt caaagaaaag
     2521 ttgactattt tagaattaaa acgtacccgt tttctatgct atgattgtgg gcagaccttt
     2581 tctgcgaaaa cggacttagt tgatgaacat catcaactaa caaaggaact gaagcaggcg
     2641 attctcatag aactgtacga aaatcaatca cgtaatctga aaatcagaag aagtaccgtc
     2701 ggctcaagcg atattggaaa ctcttactca aagattccac gacattggag ccgctcaaac
     2761 ggcattatca tcgactgttt aaacgaccaa ttagtcaaac agaaatcgtc gatgaaccgt
     2821 tgtgcacaat ggtgtcctga acgtacagcg acaccttcca tatccagagc agtcgccaca
     2881 tcacggggat ggatgccatc caaattaaaa gcaaccacgc cagtatgatg ttcaggatct
     2941 tgcggtccgt aaatggtgat accgccgatc gcttgtaatt taggtaaaac gtaggcaacc
     3001 agttcttgct cataacgatg aatattctcc ataccaatct cattcaagta atcgattgct
     3061 cctgcaatgt tcggagtacc agcttcaaat ttccatggca gctctttcca tgaactatcg
     3121 taaagattga caaaatctat catttcaccg ccgaattcga ctggctccat ttgttctaac
     3181 aattgacgtt tgccatataa tacaccgatt cctgtcggcc cgcacatttt atgcccgcta
     3241 aaggcgaaaa aatctgcatc caacgcttgt acatcaactg tcatatgcgg tgctgcttgg
     3301 gcaccgactg gactatcctc aactacaaca gcctgttcaa ccctcagccg tttcaagcac
     3361 aacaaataac cttctggatc tggtttgccg acctgaagat catcgatcgt cacaaaggaa
     3421 tcaatttttt ccttaatcat cggatgtgct tcaaaaaaat agtctagctc ccgcagttca
     3481 gaattgagac tactccgatt ttccagtgct gctgatccgc tgctcaaaat gttcagcatc
     3541 cactggtctc ccaaccgctt gacttatccc ttcataaaag gacagttctg ctgccgtccc
     3601 aacaccttgt tgatagtctg caaaaggaat tttatagccg aactgctcca gtaaataggc
     3661 ttcagtaaat agtgatgaat actctcgtaa aacatccatt cactgtcaat catcgtccca
     3721 tcaaaatcaa aaataagtgc tttggtcatc ttctttcccc cttacccaaa acaagcaaaa
     3781 gctgtgtcct gctctctcta cagtatcagc ataaaaactg ccgtctgaaa agtcaaaggt
     3841 gaaagaaatg
//
LOCUS       DAFBSV010000132         3641 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.138, whole genome shotgun sequence.
ACCESSION   DAFBSV010000132 DAFBSV010000000
VERSION     DAFBSV010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3641
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.138"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            115..975
                     /locus_tag="LLB18_002663"
     CDS             115..975
                     /locus_tag="LLB18_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HBK5245620.1"
                     /translation="MEVIIMNVGFIGAGKVGCSFGKYFQEHKIQVTGFYSKSEDSSLA
                     ASNFTSSKQYLNLRELVDENDTIFITTPDGQIQEVWQEIKNYQIKNKLICHCSGAISS
                     DIFSNIQDYGAYGYSVHPMFSISDKYNSYKKLKKSFITIEGDEKYAKFLCDFFKKLGN
                     STVIVSKENKSLYHAASVVSSNLVLGLINTSVTYLIQCGFTEKMAIEALYPLIEFNIR
                     NIKEKGIIESLTGPVERCDISTIKGHCEVLSDEDRALYMLLSKNVLEIAMLKNINRDY
                     SELEKYLGES"
     gene            987..1814
                     /gene="panB"
                     /locus_tag="LLB18_002664"
     CDS             987..1814
                     /gene="panB"
                     /locus_tag="LLB18_002664"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HBK5245621.1"
                     /translation="MKNTAVTFKESKLRNEKLTMLTAYDYSTAKIIDEAGINGILVGD
                     SLGMVCLGHEDTLSVTMEDMIHHTRAVTRGAKNTLVVADMPFMSYQTSVYDSVVNAGR
                     LIKEGRAQVVKLEGGIEVCDKIEAIVKASIPVMAHIGLTPQSVNAFGGFKVQGKDKEA
                     AKELIRAAKAVEKAGAFAVVLECVPTKLAELISKEISIPTIGIGAGAGCDGQILVYQD
                     MLGMYSDFTPKFVKKYANLSEEMNKAFTKYIEEVKDGVFPGPEHGFKISDDVLEKLY"
     gene            1829..2677
                     /locus_tag="LLB18_002665"
     CDS             1829..2677
                     /locus_tag="LLB18_002665"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HBK5245622.1"
                     /translation="MVIFKTVNDVRSQVKEWKKQGLKVGLVPTMGYLHEGHESLIRKA
                     SKENDKVVVSIFVNPTQFGKNEDLGSYPRDLERDIEVCTRGRATAIFNPEVEEMYCDN
                     ASTFVNITGLTEGLCGASRPIHFRGVCTVVSKLFNIIPADRAYFGEKDAQQLAVIKRM
                     VRDLNIDIDVVGCPIIREEDGLAKSSRNTYLSLEERSSATILNKSLTLAKEALNNGER
                     DSLKIIEIISKNINTYNLAKIDYVEVVDSLSLQRVNYIEKSVLVAIAVFIGKTRLIDN
                     FTFELQ"
     gene            2687..3082
                     /locus_tag="LLB18_002666"
     CDS             2687..3082
                     /locus_tag="LLB18_002666"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HBK5245623.1"
                     /translation="MKVTMLKGKIHRATVEQAELDYVGSITVDMNLLEAAGIYEYEKV
                     QIVDVNNGNRFETYTIAGERGTGMICLNGAAARCVSTGDKIILMAYCELNENEVKDHR
                     PKVVFVDDNNKVERVTSYEKHGRLSDIIL"
     gene            3284..3641
                     /locus_tag="LLB18_002667"
                     /pseudo
     CDS             3284..3641
                     /locus_tag="LLB18_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1420 a          409 c          721 g         1091 t
ORIGIN      
        1 atattatgat aaattaacta tggatgatat ttgaaaaaaa catactgtat atttgattta
       61 atttttattt ttaagctcat atcgtaagaa tgggacttgt agtctcactt ctttatggag
      121 gtgataatta tgaacgttgg ttttattgga gccggcaagg taggttgttc attcgggaag
      181 tatttccagg aacataaaat acaagtaaca ggattttata gtaaaagcga agactcgtca
      241 ttagcagctt cgaattttac atctagtaaa caatatttaa acttaagaga attagtagat
      301 gaaaatgata ctattttcat tacgactcct gatggtcaaa ttcaggaggt atggcaagaa
      361 attaaaaatt atcaaatcaa aaacaaatta atctgccatt gcagtggtgc aatatcttca
      421 gatatctttt caaatataca ggactatggt gcttatggct attctgtcca tcctatgttt
      481 tcaatatcag ataaatataa ttcatacaaa aaattaaaaa aatcttttat aacaattgaa
      541 ggcgatgaaa aatatgcaaa gtttttatgt gatttcttca aaaagttagg taatagtact
      601 gtaattgtat ctaaggagaa taaatctctt tatcatgccg catcagtagt atctagtaac
      661 cttgtgctag gacttattaa tacaagcgtt acatatctaa ttcaatgtgg atttactgaa
      721 aaaatggcaa ttgaagcttt atatccatta attgaattta atattagaaa tataaaagaa
      781 aaaggaatta tagaaagttt gacagggcca gttgaacgtt gtgatatttc aacaattaaa
      841 ggtcactgtg aagttttatc agatgaagac agagctttat atatgctatt atcaaaaaat
      901 gtattagaga tagctatgtt aaaaaatatt aatagagatt atagtgaatt agaaaagtat
      961 ttaggagaga gttaggagag aaatagatga aaaatacagc agttacattt aaagaatcta
     1021 aattaagaaa tgaaaaatta acaatgctta cagcttatga ctattcaaca gcaaaaataa
     1081 ttgatgaagc tgggataaat ggaatattag taggagattc tcttggtatg gtatgtctag
     1141 gacatgaaga tacactttca gtaacaatgg aagacatgat tcatcatact agagcagtta
     1201 caagaggagc taagaacact ttagttgttg cagatatgcc atttatgtct tatcaaactt
     1261 cagtatatga ttcagtagtt aatgcaggaa gattaataaa agaaggacga gctcaggttg
     1321 ttaaattaga aggagggata gaagtatgcg ataaaataga ggctatagta aaggcttcta
     1381 tacctgttat ggcgcatata ggtttaacac ctcaatctgt taatgcattt ggaggattta
     1441 aggtacaagg aaaggacaag gaagctgcta aagaattaat aagagctgct aaagctgtag
     1501 aaaaagcagg agcattcgct gtagtgttag aatgtgttcc aactaagctt gcagagttaa
     1561 tttctaaaga gatatcaata cctacaattg gtattggagc aggtgcaggg tgtgatggac
     1621 aaattcttgt atatcaagat atgttgggga tgtatagtga ttttacccct aaatttgtga
     1681 agaaatatgc taatttatca gaagagatga ataaagcatt tacaaaatat atagaggaag
     1741 taaaagatgg agtttttcca ggtccagaac atgggtttaa aataagtgat gatgttttag
     1801 aaaaattata ttaaaagggt caagaaatat ggttatattt aaaacagtga atgatgttag
     1861 aagtcaagta aaagagtgga aaaaacaagg cttaaaggta ggattagttc ctactatggg
     1921 atatttacat gaaggtcatg aaagtttaat tagaaaagca tcaaaagaaa atgataaagt
     1981 tgttgtaagt atctttgtaa atccaactca gtttgggaaa aatgaagatt taggtagtta
     2041 tccaagagac ttagaaagag atatagaagt atgcacaaga ggtagagcaa cagcaatatt
     2101 taatcctgaa gttgaagaga tgtattgtga caatgcaagt acttttgtta atataactgg
     2161 attaacagaa ggtttatgtg gagctagtag gccaatacat tttagagggg tttgcactgt
     2221 tgtaagtaaa ttatttaaca taataccagc agatagagct tattttggag aaaaggatgc
     2281 acaacagtta gctgtaatta aaagaatggt tagggacctt aatattgata tagacgttgt
     2341 agggtgtcca attataaggg aagaggatgg actagctaaa agttctagaa acacatactt
     2401 aagtttagag gaaagatctt cagctactat tttaaataaa tctttaactt tagctaagga
     2461 agctttaaat aatggagaga gagacagctt aaaaataatt gagataataa gtaaaaatat
     2521 aaatacttat aatttggcaa agattgatta tgtagaagtt gttgattctt tatcattaca
     2581 aagagtaaat tatattgaaa aatcagtttt agttgcaata gcagtattta taggaaaaac
     2641 aagattaata gataatttta catttgaatt acaatagggg gctataatga aagttacaat
     2701 gttaaaagga aaaatacata gagctacagt tgaacaagct gagttagatt atgtaggaag
     2761 tattactgtt gatatgaatt tattagaagc agcaggaata tatgaatatg aaaaagtaca
     2821 aatagttgat gttaataatg gaaatagatt tgaaacttat acaatagctg gagagagagg
     2881 aacagggatg atttgcttga atggagctgc agctagatgt gtatcaactg gagataaaat
     2941 aattttaatg gcatattgtg aattaaatga aaatgaggtt aaggatcata gacctaaggt
     3001 tgtttttgtc gatgataata ataaagttga aagagtaaca tcatatgaaa aacatggaag
     3061 gttatcagat ataattcttt aggttttgta atgttattta tatatagcta gactattatt
     3121 gaaatattta ttgattacta attggataga tgtcaataaa gtagacacaa aaagagaaga
     3181 tacagactgt agacaaagtc cattttatgt gaatcggcta cactagacta gacagaaaaa
     3241 ataaggtgtg tagaataata aaaaacacac tggaggattt ttcatgtcaa gacgtcaacg
     3301 aagaacctat tcaaaagaat tcaaacaaca aatcgtcaat ctctatctcg ctggtaagcc
     3361 tcgcgcagaa attattcgag agtatgagct tacgccttct tctttcgata aatggatgaa
     3421 gcaagcacaa tcaacgggct cattcaaaaa aagagacaac ttaacaccag aacaagcaga
     3481 attgatcgca ctaagaaaga aaaataagca actcgaaatg gagaatgata ttttaaagca
     3541 agcggcgctg atattcggac gaaaagacaa gtaattgatg ccaacaagca taaatattcc
     3601 atatcagcga tgtgcaaaat tctaaatatt tctcgtcaga c
//
LOCUS       DAFBSV010000133         3523 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.139, whole genome shotgun sequence.
ACCESSION   DAFBSV010000133 DAFBSV010000000
VERSION     DAFBSV010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3523
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.139"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            706..1023
                     /locus_tag="LLB18_002668"
     CDS             706..1023
                     /locus_tag="LLB18_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBK5245624.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(1114..1479)
                     /locus_tag="LLB18_002669"
     CDS             complement(1114..1479)
                     /locus_tag="LLB18_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245625.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1687..2169
                     /locus_tag="LLB18_002670"
     CDS             1687..2169
                     /locus_tag="LLB18_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245626.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            2366..3256
                     /locus_tag="LLB18_002671"
     CDS             2366..3256
                     /locus_tag="LLB18_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HBK5245627.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT         1205 a          540 c          647 g         1131 t
ORIGIN      
        1 ttttgagtgt agcacaaatg acttttttag ttgtctagct taattttaca atcggcgact
       61 tattgctttt gcaaaattta tttacctgtt ttctggatca acgatagtgt acattatgct
      121 atccttgttt ggattttagg acgtttaaag aggcactttt ttacataact taatccatag
      181 accttttaag catgctgtga gataataata aagaagagtt taaagcgcac cccaaaccac
      241 ttccccataa gtgtattacg ctttaaactc ttttatattt gaattcacta agaagcatac
      301 catatatttg aatttactaa gaagcatacc atatttttga aaaaaagtga gaaaaaaggc
      361 ttataattag gatttagagt aattaattag atgtttattt tataggactg atactataga
      421 ttacaaatag tatcgtattt cgcaatctta aaattatctt cttactgtga ataagataat
      481 aaaatttgta tttgtccttt ttaggtaact tattttaatc tatatacctt tctggatcaa
      541 cgaaagtata ctttatatag tcataacgcc gatggtaact atgcactgta acgataatgc
      601 tgctaaaata tctttttacg aaaaacatca caaggaaaaa cttaactatg gtattatcta
      661 aacataattt tttcggtatt taatatttaa ttaggaggta atattttgct tttttatagt
      721 aattttatct taatagtagc gatattatta cttctgaata tatggatttt tgataggagt
      781 agaaattcaa gtataggttt tagaactaaa cgaagtttgt cttctaaaaa aaattgggta
      841 tactcacaaa ctatttttta tggaggaatt gttttaatta gtttactttc ttcaacactt
      901 tattctttga atattataga tgtttccacc tcaaattcaa tatctattat tggaatcatt
      961 attgctgcaa ttattacaca actgttttta gtgtttggag agaagaaaag aagtaaaaaa
     1021 tagaaaaact agtgatagtt ttggtgatat aagaaaaaca tatatgtata aaaagaagaa
     1081 agtagcttct ctttgtacat atatggtttg tttttatgga tgccgagctt ttttataaga
     1141 taaggctacc gcccataacg acccaaggat ttgtggaact aagtaaatac ctgcaagaag
     1201 caagatcagc tgggtcggtt ttaaaggatg atagaagtaa cgccattcag taaaattggc
     1261 gcaaaataaa taggaagtga cagtagatat aatattggca atgaataaag atataatacg
     1321 cctgttcctt tgaaaataat atccagcaaa aagagataaa aatatcaatg tgatgaaccc
     1381 gcttacggaa tgataacgaa aatcaagcag taaggcgaaa tgcacataag gaacaaaaga
     1441 taaaagcaac ggaaggtttt tccagcaagt ttttatcatc tttcatcacc acctaacaag
     1501 tgttattatt ttgttagttt tattgtaaat tgaatcctgc aataatcaat tactttttca
     1561 ttatttctag attaaatgaa taaactctca tgccattatc tctaaaaaaa aagtttttcc
     1621 ccctaatttt tttagataga aaattgtata gtatgatgag agaaaaagta gtttggggga
     1681 acgttaatga gaagaaaagc agtaatcgat cggctttatt tatttttttg gttttttcct
     1741 atcgttttgc taccttttac atgggtaaat gctgttgtac aaggtgcgga gatattaggc
     1801 ctgatccaag gaagcggatt tgtggtttct aggaattttc cagctttgat tgttttctat
     1861 ttagtgataa gtgtaggtct cttattacca aaatctctga tcaatcacta caattggcag
     1921 ctgctttact tttcttgctt attagtattt acatctatgt tttctttgct gcctcgcttg
     1981 attatcggcc ctaatggttt gagcgagagt ggattgaagg atttagctta ttcctccatg
     2041 tatttcttga cgatcaaacc atggttctat ttagtaattg cctcatttat tcttgcaaca
     2101 tttttttact tctggacaga aatcaggata aaaagtgaac gatctgtatc tataaaaaat
     2161 aactattgat ggtggatcat cagtaaaaaa acatatgagc tgcgtaaaat gcatgtttct
     2221 catatgcttt ttttattatt atgtaaagaa tgcgaaaaac gtttacatga tttttacata
     2281 acttaactat atttttacag caaccatacg agggatttac agtcgactga taaactttag
     2341 ttgtaaataa gaaaggagca ataaaatgaa aaaagtattg tttactctag gtatgatggg
     2401 aattctttta gccggatgcg gctcaggatc aggaaataca gatggctctg ccacacaaaa
     2461 taattcaagt gactcaaatg aacaagtaaa aatcgttgcg gtaggttcga cagcattaca
     2521 gccgttagtc gatgcagcac aagaaagctt tgtacaagaa aatccaaatt atcaaatctc
     2581 tgtacaagga ggaggaagcg gaactggttt gagccaagtc gaagctggag cagttactat
     2641 cggaaactct gatgtatttg cagaagaaag agacggagtt gatgcttcaa aattagtgga
     2701 tcataaagta gcagtggtcg ggatggcacc aatcgtcaat aaagatacag atgtcaaaga
     2761 tatcaccaaa caggaattga ttgatatctt tacaggaaaa atcactaact ggaaggaagt
     2821 tggcgggaaa gatcaaaaaa tcaacgtcgt gaaccgtgca aacggcagcg gtacccgcgc
     2881 gacattcgaa aaatggggac tggatggtgc tacccctgtg cagtcccaag aacaagattc
     2941 atcaggaaca gttcggcagc tggtaagtca aacaccagga gcaatcagct atttagcttt
     3001 ctcatatctc gatgattcca cacaagcact aagtatcgac ggtgtagaac caaaagaaga
     3061 gaatgtagca gataacagct ggggaatctg gtcatatgaa catatgtaca cgaacggaaa
     3121 accttcccct gaagtccaaa aattcttaga ctacatgatg acagaagaaa tccaagaagg
     3181 acctgtcaaa gaattgggct atttaccaat cacaatgatg gaagtagaac gtgatcacga
     3241 aggaaatatc aaataactag cagataaaca tgccacggta gtcgttacta ttaaggaaaa
     3301 atcaactatg tttccccaca tatacatttt tcctttaatt gtgaaaaata gttcctcata
     3361 ttttgccgtt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt tattcgaaaa
     3421 aaagagctac gacatagaac tgtcgtaact ttttttggct cttcgtcaaa tcgtgttggt
     3481 gaagacaaat ttgaataaaa cttagtccga tatgcggcgc gtt
//
LOCUS       DAFBSV010000134         3459 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.140, whole genome shotgun sequence.
ACCESSION   DAFBSV010000134 DAFBSV010000000
VERSION     DAFBSV010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3459
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.140"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(577..1593)
                     /gene="tsaD"
                     /locus_tag="LLB18_002672"
     CDS             complement(577..1593)
                     /gene="tsaD"
                     /locus_tag="LLB18_002672"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBK5245628.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(1590..2054)
                     /gene="rimI"
                     /locus_tag="LLB18_002673"
     CDS             complement(1590..2054)
                     /gene="rimI"
                     /locus_tag="LLB18_002673"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBK5245629.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(2061..2603)
                     /gene="rimI"
                     /locus_tag="LLB18_002674"
     CDS             complement(2061..2603)
                     /gene="rimI"
                     /locus_tag="LLB18_002674"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBK5245630.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(2587..3309)
                     /gene="tsaB"
                     /locus_tag="LLB18_002675"
     CDS             complement(2587..3309)
                     /gene="tsaB"
                     /locus_tag="LLB18_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBK5245631.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
BASE COUNT          988 a          757 c          594 g         1120 t
ORIGIN      
        1 tatcagggtc actgcttatt ttcctcccta aaacttctga aagatccggc agttttagat
       61 cactggacaa gactcaaaga ttttctatgt gtgtttcagt tatgtaatat tcactgtttg
      121 caaaaaatac tgttagatta actagatgaa gcgtcttgtc ctcatccgat ctagattatt
      181 cgatattcct cgacaataaa cgattactca gtgagggcaa tcagaggaac ggataatgat
      241 aaataagctg taaaaaatag caaaataaca ataatgatta aaagtatgta aaaaataggg
      301 ctttgacaaa aacgtgtcac agccctattt cgattaaacg gtgtgtacct gtcaactctt
      361 cggtcacaag tcataatgtt cataaacatg aggagctgtt ttttgaaatt gttccttgtg
      421 aatcagagtt aaacgacagg cttacgaact cttgattaaa cggcgttcaa aagcttgcat
      481 acgcggtaat aagaacagcc aggtcaaaaa catgagaagc cgtttttcct gggctgttct
      541 tattacttga tgcagggcag ctttttcaca acctctttat tcagataaaa ccaagcttgg
      601 atcagcattc aactgatagc tagcaaaatt tcttttttgc atttccacat gtgctgctgc
      661 tccaatcatt gcagcattat ctccacaaag tcgaagaggg ggaatcacta gttctacctc
      721 agggagttta gttgccaaag catcctgcaa tccttcacgc aacccttgat tggccgctac
      781 acctccagct ataatcagtt gcttgactgg ataattttga caagctcgaa gtgttttagt
      841 aatcaataca tcgatcacac ttgcttgaaa gctagctgct aaatcatttt tgtctagatc
      901 ttctccacgc tgttgtgcat tatgcaccaa attgataaat gcacttttta atccgctaaa
      961 actgaaatca taattatctt catggatcat cgctcgcgga aaatggtaat tatcttttcc
     1021 ctgatgagct agctgatcga tttcttttcc gcttgggtaa gaaagaccta atactcttcc
     1081 aactttgtca taagcttctc ctgctgcgtc atctcttgtc tccccaatga tttcatatga
     1141 tccatcttct tgcatataga ctaattctgt atgtcctccg ctaacaagaa gtgccatcaa
     1201 tggaaactgg aatggtttaa ccagacgggc tgcatagata tgccctgcca tatggtttac
     1261 aggaataagc ggcaattggt gtgcccaagc aaaagcctta gctgcagaaa taccaatcag
     1321 caacgagccg acaagtcctg gtccataagt gacagcgact gccgataaat cttctgccga
     1381 cacaccagct tctaccagtg catcttccaa gcataaggtg atttgttcta cgtgatggcg
     1441 gctagctact tcaggtacta cgccaccaaa acgtttatga ctgtttattt gagaagcaac
     1501 gatgttagat aagatctctg ttccatttct aacgaccgct acactcgttt catcacaact
     1561 tgattcaatc gccagaatca attcttcatt catttcatcg tctccgtttt taactttctg
     1621 ctcataatga tcgcatcttc cgtcggattg cgataatatg atttccgttt acctaatata
     1681 cgaaactttt ctgattcata aagttttctt gctgcttcat tagatagacg tacttctaaa
     1741 aaaacatgca gcgaatcttt tatttgttcc gtaatcagta attgtaacaa atgccgtgca
     1801 tgcccttttc cttgttctga aactgcaaca gcaatatttg tgatctcgac ttcatctatt
     1861 actttcgagt atccaataaa gccacagatc tggttatctt cagctaaaag cagataatca
     1921 gagtgaggct gttggatgtc tgccaaaaac tgcattttcg tccaaggtga accatgtgga
     1981 taagcatttt cgctaatcat ccatacgcat tctgccaagt acgcttcatc aaaatctttt
     2041 tttctgcaaa tcaactaatc tcactcattt tctaaaagtt ttatcatatc caacgcatct
     2101 tcttttgttt cagtgtaata tctttttttg atcgttgttg cttgaaaccc caatttccga
     2161 taaagtcttt gtgcatcttg attactcata cgcacttcta atgacatcgt ctcacagcga
     2221 ttcattatag caaagttctc gatttcgtca ataagcagcg aaccgattcg tttacgctga
     2281 tatgccggtc gaacggcaat attcgtgata tggcaatcta aaccgaacgc tcttgaaccg
     2341 ataaaaccaa tcattcttcc attatcaaag atacctagat atagatgagg aagcggtgac
     2401 ttcaattctg atataaaggc actttttgtc catggcaatt cgccattata gacttctcgt
     2461 tcgacatcca gcagctcttt gatatcttct gtagtcaatt ctcttagtac gtaacgacga
     2521 tcgatttgtt cgactgtttt ttctgtataa atcattttat cttgaaaaaa gcttctggca
     2581 tacgctctaa attttttcaa cataactttc gtctccaggt gtgtgcgtct ccaaccattt
     2641 ttcttctgct tctactcgtt ttaaatagcg aggaagaaaa gcttgtttct ctgcaactgg
     2701 ttcaactaaa gcacctaatt gagccacagt tacaccactt ggaatatccc atgctggaac
     2761 tgtattaatc atcgcactag gcaatatttc ctttatttca gagaagaatt tgtgacaatc
     2821 actcccgacg aaataaatag cttcattcag cttttgtagt tgtgtgaaca aatcagaagc
     2881 agaaatatgt acatcttcaa gtacagtttc taatctattt tctttccagc ggtatgcccc
     2941 agcgtataca ttttttcttc gagcatcaaa catgggcaca ataatattat ccacaccgat
     3001 gcaattagcc gcgatggttt tcagactaga tactcctact agctctttat ctaatgtata
     3061 agcaatcgtt tttgctgtcg ttacacctat acgaagccct gtataagaac cgggaccatc
     3121 agaaaccgcg attcggtcaa tgtcttttgg acttatttga agatctgcaa acaattggtc
     3181 gattgcaggc atcagtgtta cactgtggtt gcgtttgata tttgtttgta tttgtccaag
     3241 aatttgttcg tcttctacca caccgatcgc caaagtttgg tttgcagtat ctattcctaa
     3301 tgtaatcata tatttgatcc tttctgctat gacattctcg ccttccattg tagcatactt
     3361 ttttattctg aggatgaaaa taccaaaggc aaaactagta caataataca tgattatctg
     3421 ctggcgggca aattttgccc cttcctgaaa cacaaaaaa
//
LOCUS       DAFBSV010000135         3403 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.141, whole genome shotgun sequence.
ACCESSION   DAFBSV010000135 DAFBSV010000000
VERSION     DAFBSV010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3403
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.141"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(75..1073)
                     /locus_tag="LLB18_002676"
     CDS             complement(75..1073)
                     /locus_tag="LLB18_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBK5245632.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKATIETDTTIETKKSKTQS
                     TEQTTTEMKQSVETSASSITESSSEEVKNTLWDTNKASKLETFVTQWGKTLGQEYKSY
                     NLQNNVSLYGTPLPQAVINGDWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVETGE
                     YLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFSDIVNGQTPQTP
                     VVEESTQQATTTTTQSTSSSGISSWEAAKESVLNNKALWLYDSPDKNVSNTNLISTNE
                     YMKDLMQDENGSYYSINIVTDDDGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK"
     gene            complement(1148..1444)
                     /locus_tag="LLB18_002677"
     CDS             complement(1148..1444)
                     /locus_tag="LLB18_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBK5245633.1"
                     /translation="MAKLIVLGGLIYGGYWLYKYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHTGYRHYWERID"
     gene            complement(1437..1730)
                     /locus_tag="LLB18_002678"
     CDS             complement(1437..1730)
                     /locus_tag="LLB18_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245634.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(1876..2427)
                     /locus_tag="LLB18_002679"
     CDS             complement(1876..2427)
                     /locus_tag="LLB18_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HBK5245635.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFLRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(2601..2900)
                     /locus_tag="LLB18_002680"
     CDS             complement(2601..2900)
                     /locus_tag="LLB18_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HBK5245636.1"
                     /translation="MLETAIEVLEKCAQLVTASEEWGYESVTMEKEEIEIGTLPKDVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTDE"
     gene            complement(2927..3235)
                     /locus_tag="LLB18_002681"
     CDS             complement(2927..3235)
                     /locus_tag="LLB18_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBK5245637.1"
                     /translation="MFQNKGQRYVTKGVMDSLPVELQALCWNLIDQNVQKQLPLDYLQ
                     IFEFSTEKGNQKLVHRQEEPEERKEYLISPKLRLKSVSQKIWAIDSGEYQTMLLPEEY
                     "
BASE COUNT          990 a          665 c          464 g         1284 t
ORIGIN      
        1 taaaaaaact gattctaaga aaattaaata atttttctca aaatcagttt ttctttgata
       61 aataatattt tcaattattt aatcatttga aaattgttag tcattccaat acgttgagaa
      121 attcttccat ctgtataaac acgaaattgt tttccaccag ccatggtcgt gtttccatca
      181 tcatccgtta caatattaat tgaatagtag cttccatttt catcttgcat tagatctttc
      241 atatattcat ttgtgctaat taaattagta tttgatacat ttttatcagg agaatcatac
      301 aaccataaag ctttattatt tagcacagat tctttagcag cttcccaact tgaaattcct
      361 gaactacttg tagattgtgt cgttgtagtt gttgcttgtt gagtagattc ttctactact
      421 ggtgtttgag gagtttgtcc attcacaata tcactgaaac cttgttttaa ctgttgattt
      481 tgagtttcgt taaagtacag ataattattt tcattacctt gattttgttg cgttaaataa
      541 actttaggtt gtccattttg aaaaccgaaa aagtaaacat gctgccctaa atattctcca
      601 gtttctacat cagaataaac tgctactaaa ttgaaatctg catgaccagt tccatcttct
      661 gaccattgta cggtaactgg tgcttcattg attgccattt tccaatcgcc attaatcacg
      721 gcttgtggta aaggagtgcc atacagactt acattattct gaagattgta gcttttatat
      781 tcttgaccta atgtctttcc ccattgtgtg acaaaagttt ctaatttgga agctttattc
      841 gtatcccaca aagtattctt aacctcttca gaagaagatt cagtgattga acttgcactt
      901 gtttccacag attgcttcat ttctgttgta gtttgttcag ttgattgcgt tttacttttt
      961 ttagtctcaa ttgttgtatc agtttctata gtcgctttag tcctcgtatt ctcagatgta
     1021 caaccagtga ataaaattcc cattcctatt agtaataaca gccatttttt cattatattt
     1081 ccccctttca atttctccct cacgtactta ttctatcaga caattaattg atctaaatgg
     1141 taatctttta atcgattctt tcccaataat gtcgatagcc cgtatggcag cggtctcttc
     1201 cttgaggact ctcagatgga ttaaaactag tagaaatttc ccttccacat cctctacagc
     1261 gataagttct cattattttt gggctattag tattattttt cttagttaga gctatgagtc
     1321 caactatgat taccccaact gtcttaatta cttttccttt atctatattc ggatgcgcaa
     1381 gcatatattt atataaccaa tatccaccgt aaattaaacc acctaataca atcagcttag
     1441 ccatgtactc gtctcctttc tttttgttta attacttttt gaatccatct tgcagagaaa
     1501 ccataaactt ctgtcaattg acggatatct acagtttttt cctgttctat catgttttcg
     1561 attctttttc taactaactc acgatcgtac attttcattg gaaaagaaat ctgttgccct
     1621 cgaaaagcaa gataaaattg atagagcaat tctgaatcca gttccatttc ctcaaaaaag
     1681 tcattcatac ttttataaga gttactcaaa caagtttcat caatctccat ctacacaccc
     1741 cctgttattt tttacataat gaaaatagca tattactggg tacattgata attcatataa
     1801 catgtatcat cacatgtatt tttaaagtca aaaagcatgt aaaactactt ataagtaaca
     1861 tgagaaaata aaatgttatt tttcttgaaa taataattga ctatctgcca attgccattc
     1921 attacgaaca tgaatactta gtgggtggga taacttacct tctgcattta tcaatacttt
     1981 ggtcatcttc ttttgtttcg cactcaattg atcgtaaata gtctttgctt gttcataagc
     2041 cacttgactc gtcgctgtaa tcgaaccaca agcaaaaata atggtattga ttttcttttc
     2101 tgtaaaaaca gtcgttaata tttccaaaga ttgttcatca tttcctcgaa gaaatacccg
     2161 aggacttttc gcttttgtgt acgaaaaaag attcacagca ataaaaccag taaatcctaa
     2221 ttgtcggata ttcttttcga ttaataacat actcaaatca ttcgtaaatg gttctgtatc
     2281 tgttggacga atagtaatga ctactgctaa tttatcttcc gcttcttttc ctttgatcgc
     2341 ccattgtcgt ttgaaaacat agcgatgggt atgatgagga tctcgccaaa cttctgtttg
     2401 tgtggtcact aattcttttt caatcatctc tttttctcct atgctatttt ttgttcaagc
     2461 acttcaatta ccattgccgt tataagtgtc aatactagtt gaaaatattt catattcttt
     2521 ctcctttttt cttcagaatt tgatgaatcg cggtaaggat atcttctaaa catttcgcaa
     2581 tcattctcaa ataatcgatc ttattcatcc gttcctccaa tctgactcca aaccaatcgt
     2641 ccttctacca gtaacccacg aacaaattct cgctggctgg taatatctgt aatgaaataa
     2701 actacatagt cttttccatc ttctggtgcg caataaatat aaagatgtgt catcactaaa
     2761 cgtggtagat gaacatcttt aggaagtgta cctatttcaa tttcctcttt ttccatcgta
     2821 acggattcat agccccactc ttcagaagca gtgaccagct gtgcacactt ttccagtact
     2881 tcgatagccg tttctaacaa gtcctttcgt tcctttcttt tagatactag tattcttctg
     2941 gtaataacat cgtttgatac tcacccgaat caatggccca tattttttga gacactgatt
     3001 tcaaacgaag cttaggtgaa atcagatact cttttctttc ttccggttct tcttgacgat
     3061 gaaccaactt ttgatttcct ttttccgtag aaaattcaaa aatttgaaga tagtctaaag
     3121 gaagttgctt ttgaacgttt tgatcgatta gattccaaca taaagcttgt aattccaccg
     3181 gcaaactgtc cattactccc tttgtgacat aacgttgtcc tttattttga aacatttctt
     3241 ttccctcctt tgctataaaa atagcccaat cttctattaa agaagattgg gcttcatgga
     3301 tataatatat atttgtaaat aaagttaatt cagttataat tatcaaaact acacaattat
     3361 taaagttttt catatctctt tgtttagtaa gtttttctaa atc
//
LOCUS       DAFBSV010000136         3352 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.142, whole genome shotgun sequence.
ACCESSION   DAFBSV010000136 DAFBSV010000000
VERSION     DAFBSV010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3352
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.142"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..174
                     /locus_tag="LLB18_002682"
     CDS             <1..174
                     /locus_tag="LLB18_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245638.1"
                     /translation="SGTAVDDIEDVDQLKQLNALLTKQLAISVQEQEKMQQMLAQLTM
                     EVASIKNGGKSNE"
     gene            167..307
                     /locus_tag="LLB18_002683"
     CDS             167..307
                     /locus_tag="LLB18_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBK5245639.1"
                     /translation="MNSFPGFENIKQFYDWGCYTDQDLLDYVNMNCLTKDQYKQITGN
                     EI"
     gene            377..796
                     /locus_tag="LLB18_002684"
     CDS             377..796
                     /locus_tag="LLB18_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBK5245640.1"
                     /translation="MEKYLNTLSVMTGVIGGTIVGLLGGMDNILHVLIFLVGVDFLTG
                     LAKAWKLKEISSEIGFEGLLKKVLIFVVIAVAVDVQKIVGNSIPLREIVIMFYVANEG
                     ISFLENISVFLPLPDKLKEVFQQIRNDTENKDRGGTK"
     gene            793..1803
                     /locus_tag="LLB18_002685"
     CDS             793..1803
                     /locus_tag="LLB18_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBK5245641.1"
                     /translation="MKKKIFVGAIIALFLLPINAFAYSINNEFNLGANEGSSQVANNQ
                     YILLHETANETATGRNEAQYMKRSWYNAYTAYIVGDGGIVYQVGQPGYVQYGAGSYAN
                     ANSPVQIELQHTHDKVTFEKNYKAYVELARDSANKYGIPLTLDTPYNQPGIKSHLWVT
                     QNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTL
                     SDGTNHSHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPD
                     VNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIP
                     KR"
     gene            1918..3126
                     /locus_tag="LLB18_002686"
     CDS             1918..3126
                     /locus_tag="LLB18_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245642.1"
                     /translation="MTAEIGIMNKSGIVLASDSASTIGDSKVYNTAKKLFTLDSMHSV
                     GIMIYGNAEFNGIPWEIIITQYKKSIGSSVFNTLEEYADNFIEFVKTASFIRSEQTEQ
                     EQMIGVFQKIISGLFESIEVDINFLISQGTQIDKDVLVKLLQTKMNTNLSQQSQTFIL
                     DIEKALFLSNYGEILKDILNSISTMEGVSEAISEEIQSYVYEIIIRDDVYSSPTGIVI
                     AGYGRMDIFPKLYSYNMFGFVMNILKYSEYESAQIGNDNGSLRSTILPFAQSDVVNTV
                     VQGVDPQITNYLSSQVDSFDDNGKNTYINIIKNISEFQQNQFIFPLLNMIALLPVEET
                     AIIAETLLNLTSFKRKYTTSVETVGGPIDVLAITPNDGPIWIKRKHYFDIDNNIGYRL
                     RKERANDYNN"
     gene            3110..3280
                     /locus_tag="LLB18_002687"
     CDS             3110..3280
                     /locus_tag="LLB18_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245643.1"
                     /translation="MITIIKPQEKSPVLKFNESNLAHNKMSITDTVFDVMVEQQKKIN
                     NNNRQRKEINQY"
BASE COUNT         1226 a          486 c          645 g          995 t
ORIGIN      
        1 agtggcacag cggttgacga tattgaagat gtcgatcagt tgaagcaatt aaatgctcta
       61 ctgacaaaac aattggcgat atcggtacag gaacaagaaa aaatgcaaca aatgttagct
      121 caattgacga tggaagtcgc aagtattaag aatggaggga aaagtaatga atagttttcc
      181 gggctttgaa aatataaaac aattttatga ttggggatgt tatacggacc aagatttact
      241 tgactatgta aacatgaact gtttaacaaa agaccaatat aagcagatta ctggaaatga
      301 aatttaatta agcacaaagt taaataaaaa gcgtactcaa acgagtgcgc ttctttgcat
      361 aaaggagaaa tagatattgg aaaaatattt aaatacactc tcagtaatga caggggtgat
      421 aggcgggaca attgttggtt tattgggagg gatggacaat atactacatg ttttaatttt
      481 tcttgtgggt gtggacttct taactggact tgctaaggca tggaaattga aagaaataag
      541 tagtgagata ggtttcgaag gattgttgaa gaaagtctta atcttcgttg tgattgccgt
      601 tgcggttgac gtacagaaaa tcgttgggaa ttctatacct ctaagagaaa tagttattat
      661 gttctatgtt gcaaatgaag ggattagttt tttagaaaac atttcggtat tccttccttt
      721 gccagataag ttaaaagagg tattccaaca aatacgaaat gatactgaaa ataaagaccg
      781 aggaggaacc aaatgaaaaa gaaaatcttt gtaggagcta ttatagctct ttttttattg
      841 ccaataaacg cctttgctta ctcgatcaac aatgaattca atttgggcgc aaacgaaggt
      901 agttctcaag tagcaaataa ccaatacatc ctattgcatg aaacagcaaa cgaaactgcg
      961 acaggacgaa atgaagcgca gtacatgaaa cgttcttggt acaatgccta tacagcgtat
     1021 attgttggcg atggtgggat cgtttaccaa gttggacaac ctggttatgt acaatatggc
     1081 gctggttcat atgctaatgc aaatagtcct gtgcaaatcg aactgcaaca tacgcacgat
     1141 aaagtaacgt ttgaaaagaa ctacaaggca tatgttgaat tagcgagaga ttccgctaat
     1201 aaatacggta ttccacttac attagacaca ccgtataatc aaccaggaat caaatcacat
     1261 ttatgggtaa ctcaaaacat ttggggcgat cacactgatc cgtatggata cttatcagaa
     1321 atgggtgtaa gtaaggaaaa actggcttac gatttagctc atggatttac agacgaaaac
     1381 ccaacgactt ctgagaacaa gcctgtcatt gatccaaccc gagcaggtgc agcaaatcca
     1441 actttatcag atggaacgaa ccattctcac attgatcagt ttggagaaat cgaaaatgcg
     1501 aacttacacg tcgctggatg gcacatcgct aactataaat acgagtatat tttcattatg
     1561 gactacaata ctgggaaaga attagctcga gtaagagctg atggaattta tagaccggat
     1621 gtaaatcaag cttataatac ttctggaaac gttggctatc atgtatcttt taacatgcgc
     1681 aatttcccta ataagaaagt atacgtcatg atgcgggcaa cgaatgatcc agaaggaaac
     1741 actaaaggcg gtgcgcaaga tttccatgac aaacgttggt atttaaatat tcctaaacga
     1801 taaaaatagc tcctcgttga ggagcagtac atagaattga aaattaacgt taaatcaaaa
     1861 aaatatttac aagatgttta tttaagtaga taataaaaga aaaaagcagg tgaaattgtg
     1921 acagcagaaa ttggtattat gaataaaagt ggaatcgtgt tagcttcaga ttcagcatct
     1981 acgattggag atagcaaagt atataatact gcaaaaaaat tatttacttt ggattccatg
     2041 cattctgtag gtatcatgat atatggtaat gctgaattta atggtattcc ttgggaaata
     2101 atcattactc aatataagaa aagcattggt agttctgttt ttaatacttt ggaagaatac
     2161 gcggataatt ttatagaatt tgtcaaaaca gcatctttta ttagaagtga acagaccgag
     2221 caagaacaaa tgattggggt ttttcaaaaa ataatttcag gtttatttga gagtatagaa
     2281 gtagatatta actttttaat aagccaaggt acacaaatag acaaagatgt cctagtgaag
     2341 ttattacaaa caaaaatgaa taccaatttg tctcaacagt cccagacatt cattttagat
     2401 attgaaaagg cgttatttct tagtaactat ggagaaatat taaaagatat tcttaatagt
     2461 atttctacaa tggaaggtgt ttcagaagct atatcagagg aaattcaaag ttacgtttat
     2521 gaaattataa ttagagacga tgtttattct tcccctacag gaatagttat agcaggatat
     2581 ggaagaatgg atattttccc taaactatat tcttataata tgtttggatt tgttatgaat
     2641 attctgaaat actcagaata tgaaagtgct caaataggaa atgacaatgg ttcattaaga
     2701 tctactatat taccatttgc tcagtctgat gtggtaaata ctgtagttca aggggtagat
     2761 ccacaaatta ctaattatct gtcgagtcaa gtcgatagtt ttgacgataa cggaaaaaat
     2821 acctatatta atattataaa gaatatttca gagtttcaac aaaatcaatt catatttccg
     2881 ttactaaaca tgattgcttt actcccagtt gaagaaacag caattatcgc agagacttta
     2941 ttaaatttaa ccagttttaa acgaaaatat actacttctg tagaaacagt aggtggccca
     3001 attgatgttt tagctattac acctaatgat ggccctattt ggattaaaag aaaacattat
     3061 tttgatattg ataataatat tggatacaga ttgcgaaagg agagagcgaa tgattacaat
     3121 aattaaacct caggaaaaat cccctgtttt gaaatttaat gagagcaatc tagcccataa
     3181 taaaatgagt ataactgata cagtatttga tgtaatggtt gagcaacaaa aaaaaattaa
     3241 taataacaat agacaaagaa aagaaattaa ccaatattaa tgttttttct gttgcgtttt
     3301 ttgcagtcat aatttaaaac ctcgctcaat cttgggcgag gtcttttttt at
//
LOCUS       DAFBSV010000137         3294 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.143, whole genome shotgun sequence.
ACCESSION   DAFBSV010000137 DAFBSV010000000
VERSION     DAFBSV010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.143"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            39..590
                     /locus_tag="LLB18_002688"
     CDS             39..590
                     /locus_tag="LLB18_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF334 domain-containing protein"
                     /protein_id="HBK5245644.1"
                     /translation="MKRLEASTSNFNNKLDVFEEKTKHARLNFETTAKHYIKRLDEDN
                     LKLDFQQAIQDELSDTKDEIREVTKQAREETKEYKEILESKIKDHNKVVDKSNTALKV
                     MTKGVTNIFFVLIIFVLVMLVTGPIGHFFGIEHLYSFINGFIDDHESAWRYLMLILYA
                     VPYVFFAIILWLIALFFRVFNDL"
     gene            1266..1520
                     /locus_tag="LLB18_002689"
                     /pseudo
     CDS             1266..1520
                     /locus_tag="LLB18_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405927.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            1590..2102
                     /locus_tag="LLB18_002690"
     CDS             1590..2102
                     /locus_tag="LLB18_002690"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK5245645.1"
                     /translation="MTNKNNERYSTELKATAIKKMMPPENRGIRQLSQTLGIPEATLC
                     SWRKKARIQGNTTPGTKKNVEKWSSEDKFLIVMESFSMNQVELAEYCRKKGLFKEQIE
                     AWKKTCLSANEQEENRTRELATELKEEKKQARQLEKELRHKEKALAEAAALLLLRKKA
                     HAIWGDQEEE"
     gene            2099..3136
                     /locus_tag="LLB18_002691"
     CDS             2099..3136
                     /locus_tag="LLB18_002691"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBK5245646.1"
                     /translation="MISSSDRKQAVELIQEANRNGARLTYACNELNISVRTYERWTRE
                     GTIAHDQRPLAKRPVPKNKLTDQEREKIIETVSKKEFMNLPPSQIVPKLADCSIYIAS
                     ESSFYRVLREKNMQHHRGRSQVSQKRIPPSHLATKPNEVWTWDITWLKGPIKGLFYRL
                     YLIIDLFSRKMVGWEIWESEEARHAEKLIKQTVLKERIQGQPLVLHSDNGSPMKAATF
                     QVLLEKLGIQSSYSRPRVSNDNPYSEAAFRTLKYRPEYPNNGFKTIDDARKWTKEFVD
                     WYNDSHLHSGIQFVSPAACHEGRHLAILEKRKQVYEDAKKRHPERWSKGVRNWTPHQS
                     VALNPLKETES"
BASE COUNT         1214 a          555 c          654 g          871 t
ORIGIN      
        1 agagcgagca agacaggaac gagagaacaa acatactcat gaaaagacta gaggcttcga
       61 cctcgaactt taataataag ttagatgttt ttgaagaaaa gactaagcat gcaagattaa
      121 actttgaaac aactgcaaag cactatatta aacgacttga tgaagataat ttgaaattag
      181 attttcaaca agctattcaa gatgaattaa gcgatactaa agacgaaata cgtgaagtga
      241 cgaaacaagc gagagaagaa acaaaagagt ataaagaaat cttagaaagt aaaataaaag
      301 accataacaa agtggttgat aaatcgaata cagcgctaaa agtgatgaca aaaggcgtta
      361 caaatatatt ttttgtgcta attatttttg tacttgtaat gcttgtgaca ggtccgatag
      421 gtcatttctt tggtattgaa catttatata gctttattaa tggttttatt gatgaccacg
      481 aaagtgcatg gcgatatttg atgttgatac tttatgcagt accctatgta ttcttcgcta
      541 tcattctgtg gctcatagca ttgtttttta gagtatttaa tgacctttag gtagatttat
      601 atataaaaag ggctaaatac gcaaaatacc cccttaaaat gcaaaataaa tgcaaataag
      661 ggggtaactc cttatgaaaa aacaactaat agtattataa cacgttttta tgccgagaaa
      721 acttattggt tggaatgggc tatgtgttag ctaacttgtt agcgagttgg ttggacttga
      781 attgggatta atcccaagaa agtaccaact caacaacaca taaagccctg taggttccga
      841 ccaataagga aattggaata aagcaacgaa aggagttgag taaaatgagt gagaaaacga
      901 agaaaatcat tcgagtatca ttagcttttt cacaagtagt agtgcaatca ttgatagttt
      961 attatactta ccagcaatat aaattatcta aagagaatta agttttgatt atgtaataag
     1021 ttttggtact aaaaaagact tgatctaatt agaccaagtc ttttgttagt gttatattaa
     1081 taacaaaata aaaataagaa gtcgctcact ccccgaccaa agtttgtgag caaaataaac
     1141 agtcgatgtt tgtttcttaa ttgtatatct tgatattaaa cgatttaaga ttattcttca
     1201 agatatatat tcgcaaatgt aattggaaaa gcgacttctt aaacaaaatt aaggagtcgc
     1261 tttttatggc aaaaataacg aaaaatgagc aagaaaattt ggtggaaaat tacacaaaaa
     1321 aaccggcgta ctctaatagc cggttagacg cacatttcgt gtgcacttct aatccgaaat
     1381 tgagctttga cgctatgacg atagtcggaa accttaataa aaacagcgct aaaaagctat
     1441 ccgattttat gagtttagat ccacaaatta gactttggga tatacttcaa acaaaattta
     1501 aagctaaagc actacaagac cccctatgtt aggctagttg tcgtatagga taataagtta
     1561 taataaagac tatacggagg atgattacca tgacaaataa aaacaatgaa cgttactcta
     1621 ccgaactgaa agcgacagcc atcaagaaaa tgatgccacc cgaaaatagg gggattcgcc
     1681 aattaagtca aactttgggc attccagaag cgactctttg ttcttggcgt aaaaaagcta
     1741 gaattcaagg gaatactaca cccggaacga aaaaaaatgt cgaaaaatgg tcaagtgaag
     1801 ataaattttt aattgtgatg gaatcattct caatgaacca agtagaactt gcggaatatt
     1861 gccgaaagaa gggcttattt aaagaacaaa ttgaggcttg gaagaaaacg tgcttatctg
     1921 cgaatgaaca ggaagaaaat cgaacgagag aacttgcaac tgaactaaaa gaagagaaaa
     1981 aacaagcgcg tcaattagag aaagaattac gtcataagga aaaagcatta gcggaagccg
     2041 ctgctctctt attactaaga aaaaaagcac acgcgatttg gggggaccaa gaggaagaat
     2101 gatttcatct tcagatcgca aacaagctgt tgaacttatt caagaagcca atcgcaatgg
     2161 ggcccgtctc acctatgcct gtaatgagct gaatattagc gttcgaacct acgaacgatg
     2221 gacgcgtgaa ggtacgatag cgcatgatca acgccctttg gcgaaacgtc ctgtacccaa
     2281 aaataaactg acggatcaag aacgcgaaaa aataatagaa accgtttcaa aaaaagaatt
     2341 tatgaatttg ccacctagcc aaattgtacc aaaacttgcg gattgctcga tttatattgc
     2401 atcagagtct agcttctatc gtgtattgcg agaaaaaaat atgcaacatc accgtggccg
     2461 aagtcaagtt tcacaaaaac gcataccgcc aagtcacctt gcgacgaagc caaatgaagt
     2521 ttggacttgg gatattactt ggctaaaagg tccaataaaa ggactctttt accggttata
     2581 tctcatcatt gatttattta gccgtaaaat ggtaggctgg gagatttggg aatcagaaga
     2641 agctcgtcat gccgaaaaac ttattaaaca gacggtgctt aaggaacgta tccaaggaca
     2701 gccgttggtt ttacactccg ataatggcag ccctatgaaa gccgcgactt ttcaagtctt
     2761 actcgaaaaa ttaggaattc aaagttctta ttcaagacca cgagtgagta atgacaatcc
     2821 ttattcggaa gcggctttcc gaacgttaaa atatcgacca gaatatccca ataacggctt
     2881 taaaacaata gatgatgctc gaaaatggac gaaagagttt gtcgattggt ataacgattc
     2941 tcatttgcat agtgggattc aatttgtgtc tcctgcagcg tgtcatgaag gacgacatct
     3001 cgctatttta gagaaacgaa agcaggttta cgaggacgct aaaaagcgcc atcctgaacg
     3061 ctggtcaaaa ggtgttcgaa attggactcc acatcaatcg gtggcgttga atcctttaaa
     3121 agaaacagaa agttaacagg agcataatct ttcaagatta tcaaataacc ctcgtcaccc
     3181 aataggggaa aaagttattc ttcccctatt ggataacgag gccaaccgac catagggagg
     3241 ttctgctttt tgataggtgg aaaataaaaa tacgacaact atattgacaa acac
//
LOCUS       DAFBSV010000138         3278 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.144, whole genome shotgun sequence.
ACCESSION   DAFBSV010000138 DAFBSV010000000
VERSION     DAFBSV010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3278
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.144"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            4..588
                     /locus_tag="LLB18_002692"
     CDS             4..588
                     /locus_tag="LLB18_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBK5245647.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(665..1858)
                     /locus_tag="LLB18_002693"
     CDS             complement(665..1858)
                     /locus_tag="LLB18_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBK5245648.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            1922..2302
                     /locus_tag="LLB18_002694"
     CDS             1922..2302
                     /locus_tag="LLB18_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBK5245649.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            2376..2738
                     /locus_tag="LLB18_002695"
     CDS             2376..2738
                     /locus_tag="LLB18_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245650.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT         1113 a          534 c          623 g         1008 t
ORIGIN      
        1 aatatggcat tcccacaact agatttaaaa agtgaaaaag gaccaaaagc tgttatcaaa
       61 acaaaccgtg gtgacattac tgttcaatta ttccctgaac tagcaccgaa gacggttcaa
      121 aatttcattg aactttccaa aaaaggttat tatgatggcg tgatttttca ccgcgttatt
      181 cctgatttca tgatccaagg cggcgatcca actggaacag gaatgggtgg cgaaagtatt
      241 tatggcgaaa gttttgaaga tgaattcagt cgtgaactgt tcaaccttcg cggagcttta
      301 tctatggcaa attcaggtcc aaacacaaac ggaagccaat tctttattgt aaataacaca
      361 aatgtgccag ctaatatgct tggacaacta gaaggtgctg gattcccatc agaaatcatt
      421 gaagcgtata aaggtggcgg aactccttgg ctagatttcc gacatacagt ctttggacat
      481 gtactagaag ggatggacac agtagatgaa atcgcaaatg tacaacgtgg tccacaagac
      541 cgacctgtac atgatgtagt gattgaaaca attgaaattt cagaatagtt tggtatggta
      601 cggagtaatt atgaaaaagg acgaaaccta gtaaggtctc gtccttttat tttgaataaa
      661 tgatttaatc gattgtctct aaagcatact tgattcgatt aagtccttcc agtaaagttt
      721 cttctggaca agcaatattc aagcgcatat gcccatgacc ggaaggacca aacgtgatgc
      781 caggatttaa tacgactttt cctttccgaa caagagtgtt ctccaattct tggtcgtctg
      841 aaatataggc ggtaaaatct aaccacatta agtaagttcc ttcagggttc attattctca
      901 ctttcggaag atactgttca aaaaactgat taactgtttg aacatttttt tctagataag
      961 gaatcagttg gcttaaccat tctccacccg tctcataagc cgcttgggtt ccaatcagtc
     1021 caaaagtgtt gatttcgtgc tgttggttca tcactaaatg tttttcaaaa tcagctttca
     1081 tctctggatt tttgataaat accattgaat ttttgattgc agctagattg aaagtcttgg
     1141 ttgcggaagt aaaagcaact agtagatcat ctaaattagg atcaatcgtt agcatggaag
     1201 taaatgtatg atcgaataaa gttaaatctt gatggatctc gtcactaaac agaatcactt
     1261 gatgttttaa acacaattcg cttaactgtt tcaattcttc tttgctccaa acacgccctc
     1321 caggattgtg aggattgcat aaaatcattg cttttacatt gttttcttcg atttttttct
     1381 ccatgtcaga caagtccatg atgaaatgat tatttttttc tagcaaagag cttcgaacga
     1441 tgtgacgttg atttgtttct ataatagagg aaaatggagg ataaactggg tcatgaatca
     1501 aaatagaatc gcctggtttt gtaaaagttt gtactgctgc agctaaactg gttaacacac
     1561 cacttgtaaa aacgatattt tctttcgtca actccacagc atggtgttgg cgttcccaat
     1621 gaatgatagc ctgatatagt ttatcagaca gagtggcata accaaagatt ccatgtttga
     1681 tgtattcact aaacgcttta gctaccccac cgggagacaa gaagtccata tctgctaccc
     1741 acaaaggaag taagtcatcc atttgatatg tctcagcaat tgcgtcccat tttacacttt
     1801 ctgtatcttt tcttgaaatc tgtttatcaa attcgatcat cttaagacct ccagtcattt
     1861 tcgtcgcttc tttttttgag ctatttacag tataatgata aatgcgaaga gagggaagta
     1921 gatgacttat aaaattggac aaataattga aggaaaagtg acagggatac agccttatgg
     1981 cgcattcgtt tctcttgata acgagacgca aggacttatt catgtttcag aagtacaatc
     2041 cggttatacg aaaaatatcc attcattgtt aaaagtcgga cagccagtaa cagttcagat
     2101 catcgacatt gatgaatatt ccaaaaaaat cagtttatct ttaagaacgt tagaaaaaac
     2161 aaatccagct gttccatatc gcagaaaaag gtatttcacg aataaaaatc gtaagatcgg
     2221 atttaccact attgcggagc agttacctat ttggatagaa gaagcattat ctgaactaga
     2281 acggaaagaa aataagaaat aaaaagtgta ttttttctga aaatgtgcta gaatttttat
     2341 gtaagccata gaacaagttg atcgaggtgg aaattttggc aagcaaaaga gttgctggta
     2401 caattatgtt gcatttggag gatggtacta aaaaattttt ggtccattca attgatgaca
     2461 agttggaatt tgcgttagcg gaactttctg aaggaaagac tggtttagcg aatatactta
     2521 atttcttaaa agaaatagtt catatcgatg ttagcaagat tagtttgatg gaattgacaa
     2581 atacacatat taaagaggaa aatgttccgt tgtttgtctt tgaaactgaa caaaagaatc
     2641 aaagagaaga attaggcgaa ggatatattt gggaagaacc aggtcaaatg cgctctgttc
     2701 ttggaactta cgaagtagag ggagtgcctt tcttctaaaa tacagattaa gcgaacaaag
     2761 aagtttgaat ttttttcaaa cttctttttt tattgtttgg tccaaaaaat acaatgaaat
     2821 gttctgctaa agatagtttt ttagtgcatt ttattttcaa aatatgttga aaacggttgt
     2881 ataacgaata ataataattg atcgaaaaat catttcacaa agtaatgctt aatttatagt
     2941 tgaccaagga agaaatacat gataaattta acagcgttga ttctgaagtg gatgttatat
     3001 cacatttcta aaaaatttaa aaaatagtta ttgacatgtt actaacgaca tgataagata
     3061 actgagtcgt taaaaaagaa ccacttgcga agcttgattc tatcgaaaaa aacttcaaaa
     3121 aagttcttga caaataacaa acgataagtt atgataaatg agttgctgaa agatttcgaa
     3181 aaacgaaatc gaaaaaaact tttaaaaaag agttgacaat cgtttgtctc tctgatatga
     3241 tataaaagtt gctacggcag ccaaaaacga atcgggga
//
LOCUS       DAFBSV010000139         3272 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.145, whole genome shotgun sequence.
ACCESSION   DAFBSV010000139 DAFBSV010000000
VERSION     DAFBSV010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3272
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.145"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(368..1486)
                     /locus_tag="LLB18_002696"
     CDS             complement(368..1486)
                     /locus_tag="LLB18_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245651.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1957..3264
                     /locus_tag="LLB18_002697"
     CDS             1957..3264
                     /locus_tag="LLB18_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBK5245652.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
BASE COUNT         1025 a          679 c          589 g          979 t
ORIGIN      
        1 tttttaaacg gtgttccaga agtagcttct tcggaaataa gccgaaattt cacaaaaatt
       61 tgagaaataa tttttgtcaa tctcttctta tttcttgaag ctgaccactt ctgtcacaac
      121 ctcttcctta aacggtgttc aaaagcttgc atctgcggta ataagcccac caaacaaaaa
      181 atatgaagag ctatttttgc ttgctgttct tattacttga tgcagaacag ctttttcaca
      241 acctctcata cacggtgttt aatcagctga ccttcggtat tagctcaaaa aacggaaaaa
      301 tatgtgaaac tatttttccg tttgtttctc taatactcag gtcaaaacac tgatttcaca
      361 acctctttta ataacgaaga atcgctgtca gactcttttc atctggcgca tctttttgat
      421 ccaaaataaa cactttcccg ccattaatga tcacatcatc tgctaatgca ttcaacactt
      481 gacgccgatc atattctgtt tcaggatctt caccgaaacc atcagctaag tttgacgtag
      541 cgataaataa atgtgacact tttccttctt tcgcagctgg aacgatatca actaactgat
      601 cgatgaattt cttatctaag agtttattgt attcttttga ttcttgagct gcgagttcac
      661 ttgacagctt cttcgcccct tcttcgatat ctctaaagga tagctgcgca ggagaagcag
      721 aaatcgcaac gtctgcacaa taatagggat ttttagcaat ttttttgaac atcgtctgat
      781 tttctggtaa tgcaaataaa taaatcggcc attgttcagg attttcgaaa gaatccttca
      841 agtacgtatc aacagcttgg taatagttga cccaatcgat ctctacttct tcatcttttg
      901 gatttacgcc atggaaagtt actccatctc gggctccgcc tcctccatta gaagagaagt
      961 tcaaaccgcc acctgtcagt tcagatccca atgcagtaac gacatcaacc ggtgcccctt
     1021 ctggtagaga tacttctttt acttgtttgt tgctgacctc atacaatttc atggagtcgc
     1081 ggttcaatcc caataaataa taagaatagt tgaactgccc atttttgata atagccagta
     1141 aataaggaag atcacttaca tagtattgat cgtctaccgg gatactcaaa cgatggatat
     1201 aggtctggtc agcagttata atgaccgcta cactcgtagt tgcactacgc caaaacgaag
     1261 gatctcctaa caaattttca attttttctt ggaacgggga ccagtcatgt tcggaatatt
     1321 ttttctcaaa acgtttcttt gcttctttcg caaaattttt gaatttgatc tgatcttttt
     1381 ccacatcttg atgggcgaca tgcgtattca gcatgatcgt gacgaatggt cctttagcgc
     1441 cttctgaagt caattgtgtc aataattctt tatccttttt tgccataaac gtacccctcc
     1501 taaaaaaatc attcctttgt ttctatctaa agtctaccac aacactattt ttccatacaa
     1561 taaaacgtat ctaaaaaaat aaaacggttt ctacggtttt aaatttagct atttttttaa
     1621 gttatcttca taatttcctc aattatttag ccccagtctt caactattct tcatgaaatg
     1681 ctgataaact aagaaaaaga ataaaagagg tggatcttat gcatttgatt atgattttca
     1741 gtttattaag tattatcagt ttatttgctt tcagcgcttc ccgcttatta gatgcggaaa
     1801 cacagcctat tcctgtaaaa gtacgtaaaa acgaccgcta aacttccata acgcgcgttc
     1861 ttatcctaaa gttttttcag aaacattgaa actctctccc ctctctgata aaattttaat
     1921 ttgtagcgaa acaaattaat tacaaggaga tcggatatgt ccataaaaaa aacacgtcta
     1981 gtcctattat tggctagtct cattctttgc cttgcttctt ttctaccagc tgttgctgtg
     2041 caagctgaag atacgttcaa agtaaatgca aaagcagctt ttgctgtaga tgcgcaaagc
     2101 ggtaagattc tttatgatca agatggagaa aaaaccatgg ggatcgcttc aatcacaaaa
     2161 atcatcggtc tttacatcgt ccttgatcaa gtaaaagaag gaaaactgtc atggggtgat
     2221 aaagtttcga tttcagatta tgcagaaaat ttgagtatca ccccagattt atcgaatgtt
     2281 cctttgcata aagaaaacac ctacactgtc aaagaattat tcgactctgc aatcatccag
     2341 tcagccaatg cttcaatggt ggccttggca gaaaaaatct ctggcagcga agctaaattc
     2401 actgaacgaa tgaaagaaca attgaaagat tggggaatca aagatgcaac aatcgttaat
     2461 gcatcaggat tgaacaactc ttatcttggc gaaaaccgac cagaaggcac tggagaaaac
     2521 gacgaaaatc aaatgtctgc tcaagatgtg gccatcgttg cccgccattt gatcttggat
     2581 ttcccagaaa tactggatgt atcaagtact acgacccaaa tgtttggcga aaatacgcaa
     2641 tcaccagtgg aaatggtcaa ctggaactgg atgctcccag gattcgttaa ttacaaggaa
     2701 ggcgtggacg gattaaaaac tggtacgact gagcttgcag gtgcttgttt cgttggtacg
     2761 atcactaaaa acgatcaacg gatcatcact gtcgtattga atgcggacgg ccatgcggaa
     2821 aacccgagtg cccgcttcaa tgaaacagac cgtttgatgg actactgcta tgacaattgg
     2881 tcagaaaaag agctcggaaa agctaacgca agtattccta gtctaaaaac cattgatgta
     2941 aaagacggaa aagaatcaac agttcctgtt gtgcttaaaa gccctgtaaa agtatgggta
     3001 cgaaacgata tggatactgg caaattaacg atcacgccaa cacttgacaa gaagcaagtc
     3061 actgacaatg agatccaagc acctatggat aaaggtacaa aaatcggtac cgctacgatc
     3121 accttggcag acgataaatt aggctattta gaagacaaca atgcaccatc aacagagatc
     3181 attacggata aaacagtgga aaaagcgaat atattcgtga ttggctggcg acgcgtcgca
     3241 gaatttttcg gcaacttgtt ttaattgaac aa
//
LOCUS       DAFBSV010000140         3003 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.146, whole genome shotgun sequence.
ACCESSION   DAFBSV010000140 DAFBSV010000000
VERSION     DAFBSV010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.146"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            180..884
                     /locus_tag="LLB18_002698"
     CDS             180..884
                     /locus_tag="LLB18_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HBK5245653.1"
                     /translation="MFAENLKFLREKYNIDQQELAEKLGRKSSSSISEWEKGKYTPKL
                     KTLNEIAKIFNVDIDDLMNIDLSISNQIYNILPIYNQLNDENKVATYEFASNRLEEQK
                     QENVLDFPKKEKIPTVHNSASAANPTELTYGDTVVEEEEFERVPSAADFAVPIIGDSM
                     EPVIRNGQFVFVKEQPDVEDGEIAIVELGGDGVTCKEIYKDYENQTIILRSINDLYED
                     RIVSPEQIRIIGKVVF"
     gene            971..2260
                     /locus_tag="LLB18_002699"
     CDS             971..2260
                     /locus_tag="LLB18_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HBK5245654.1"
                     /translation="MGVLLFLVGIVLIIMGSSKLSEAKKLKDKTSALESKVKEYSQEL
                     NARETFISEKEKNISKLNKNLSTLENKIDILNAESQRLDDEINQKYDTSLVTIYKSVI
                     IPNIDETSSSEIKNKLSLLKIKEKDFILDGAINIPSYLNNREANNIKKKMLIPLESEI
                     TGLLNKLTISNVDSTREKIIRTFDKINKLFKNDEAEFKKELLELKLQELELNYSYIVK
                     VNDEKEQQKAIKEQMIEEEKVRREIEREKKRIDKEERQFNSEITKLMAYMQKASADVE
                     KELYADKIKELEEKLRELETVKEDVLQRELNTRAGYVYVISNIGSFGEDVYKIGMTRR
                     LEPMDRIKELSSASVPFEFDVHAMIFSEDAPTLENQLHSHFRKNEVNKVNQRKEFFKV
                     SLDEIEKVVLENYNGTVSFTKLAQAEQYRRSLELTDV"
     gene            2326..>3003
                     /locus_tag="LLB18_002700"
     CDS             2326..>3003
                     /locus_tag="LLB18_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBK5245655.1"
                     /translation="MKRVALYMRVSTEQQAKHGDSLREQKETLYEYIEQHKDLKVVNE
                     YVDGGISGQKINRDEFQKLLQDVKENKIDLILFTKLDRWFRNLRHYLNTQEILEKHNV
                     SWNAVSQQYYDTTTAYGRTFIAQVMSFAELEAQIDSERIKAVMANKIAQGEVVSGKTP
                     LGYSIENKKLVINDDAPIVIDIFNYFLSSGSLRKTVYYLGSQYGIVRDYQSVKNMLTN
                     KKYIGELR"
BASE COUNT         1218 a          399 c          515 g          871 t
ORIGIN      
        1 ttaactttct gactaaatta tatacttcgg tttttccgaa gtcaagtgca tatttcagtt
       61 ttcctgaaat cgatttctat tttgcgtaaa tacttcttta aaaacactaa aatattttct
      121 aagaaacctg ttacattttt tccgaaacgg tgttacaatt aactcaagga ggtgttacta
      181 tgttcgctga aaatctaaag tttcttagag aaaagtataa tattgatcaa caagaactag
      241 ccgaaaaact aggaagaaaa agttcatcct caataagcga atgggaaaaa ggaaaatata
      301 caccaaaatt aaaaacctta aatgagatag ctaagatatt caatgttgat atagatgatt
      361 tgatgaatat tgatttatct atatctaatc agatatataa tatccttcct atatataatc
      421 agcttaacga cgaaaataaa gttgctacct atgaatttgc aagtaatcga ttagaagaac
      481 aaaaacaaga aaatgtccta gattttccta aaaaagaaaa aatcccaact gttcacaatt
      541 cggcttcggc tgccaatcca acagaactta cttacggtga tacggttgtc gaagaggaag
      601 aatttgagag agttccaagt gctgctgact tcgcagtacc tattataggc gattcaatgg
      661 aacctgttat caggaatgga caattcgtat tcgttaaaga acaaccggac gtagaagatg
      721 gggaaattgc tattgtggaa ttaggtggtg acggagttac atgtaaagag atatataaag
      781 attacgaaaa tcaaacaatc attttacgtt ctataaacga cttatacgaa gatagaattg
      841 tatcgccaga acagattaga attatcggaa aagttgtatt ttaaaaaaat tcccatgccg
      901 gagccgtcaa cttcggtaag ggtttatatg attttgacaa ttattttata aaagaagcga
      961 ggcgttttga atgggagtac tattgttttt agttggaata gttttaataa ttatgggtag
     1021 tagcaaatta tctgaagcta aaaaattaaa agataaaact tctgccttag agagtaaggt
     1081 aaaggaatat tctcaagaat taaatgctag ggaaacgttt atatctgaaa aagagaaaaa
     1141 cataagtaaa ttgaataaaa acttgtcaac gctagaaaac aaaattgata ttcttaatgc
     1201 tgaaagccag cggttagacg atgaaattaa tcaaaaatat gacacatctc tggtcactat
     1261 ctataaatca gtaattattc cgaatataga tgaaacttct tcatccgaaa taaaaaacaa
     1321 actttcttta ttaaagatta aagaaaagga ttttatttta gacggtgcaa ttaatattcc
     1381 ttcttatttg aataatagag aagctaataa tattaaaaag aaaatgctta taccattaga
     1441 atcagaaata actggacttc tcaataaact tactatttct aacgtagatt caactagaga
     1501 aaaaattata agaacttttg ataaaataaa caagcttttt aaaaacgatg aagcagaatt
     1561 caaaaaagaa ttacttgaat taaaacttca agaattagaa ctcaactatt catacatagt
     1621 taaagttaac gatgaaaaag aacagcaaaa agcaataaaa gaacaaatga ttgaagaaga
     1681 aaaggtaaga cgtgaaatag aacgtgaaaa gaaacgcatt gataaagaag aacgacagtt
     1741 taactcagag ataactaagt taatggcata catgcaaaaa gctagtgctg atgttgaaaa
     1801 agaactctat gctgataaaa ttaaagaact ggaagagaaa ttaagagaac tagaaactgt
     1861 caaagaagat gtattgcaaa gagaacttaa tactagagct ggctatgttt atgtcatcag
     1921 taatatcgga tctttcggtg aagatgtcta taaaatagga atgactagac ggttagaacc
     1981 tatggataga attaaggaac ttagtagcgc ttctgtacct tttgaatttg atgttcatgc
     2041 aatgatattt tcagaagatg caccaacatt agaaaatcaa ctacattcgc attttagaaa
     2101 aaacgaagtc aataaagtta atcaacgaaa agaattcttt aaagtatctc ttgatgaaat
     2161 tgaaaaagtt gttttagaaa attataacgg aactgtatct tttactaaac tagctcaagc
     2221 tgaacaatac agaagatcat tagaattaac agatgtgtag taaaaagatt agccttcggg
     2281 cttttctttt acaacgataa gaacatacat tcgaaaggag ataacatgaa acgagtagca
     2341 ttatatatga gagtatcaac tgaacaacaa gccaaacatg gagatagtct tagagaacaa
     2401 aaagaaaccc tctatgaata tatcgaacaa cacaaggatt tgaaagtagt taatgaatat
     2461 gtagacggtg gtatttctgg tcaaaaaata aatcgtgatg aatttcaaaa actattacaa
     2521 gatgtaaaag aaaataaaat agatctaatt ttatttacaa aattagatag atggtttaga
     2581 aatctacgac attatttaaa cactcaagaa attttagaaa aacacaatgt ttcttggaat
     2641 gctgtttctc aacaatatta tgatacaact acagcgtatg gcagaacttt cattgcacaa
     2701 gtaatgagtt ttgctgaatt ggaagcccaa attgattcag aacgcatcaa agctgttatg
     2761 gcaaataaaa ttgcacaagg tgaagtagta agcgggaaaa ctccgttagg ctactctata
     2821 gaaaataaga aattagtaat aaatgatgat gctcctatcg tgatagatat attcaactac
     2881 tttctttcta gtggtagttt aagaaaaact gtttattatt taggctctca gtatggaatc
     2941 gttagagatt atcaaagtgt taaaaatatg ttgacgaaca aaaaatacat tggtgaatta
     3001 aga
//
LOCUS       DAFBSV010000141         2953 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.147, whole genome shotgun sequence.
ACCESSION   DAFBSV010000141 DAFBSV010000000
VERSION     DAFBSV010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2953
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.147"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..903
                     /locus_tag="LLB18_002701"
     CDS             <1..903
                     /locus_tag="LLB18_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HBK5245656.1"
                     /translation="GFTKQSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSY
                     PLVGPATWDGKVYVQNLFNAAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGF
                     KACTDPRQAAYAFERNYERPAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESL
                     IGQRIGNGQCYGLSAEYSGYLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGW
                     KVIQNPRYDQLVVGAIINWARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELG
                     MICGKLDRQYYSASAISSIVIPPK"
     gene            916..1824
                     /locus_tag="LLB18_002702"
     CDS             916..1824
                     /locus_tag="LLB18_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HBK5245657.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETRIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKIETVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            1824..2441
                     /locus_tag="LLB18_002703"
     CDS             1824..2441
                     /locus_tag="LLB18_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245658.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            2445..2894
                     /locus_tag="LLB18_002704"
     CDS             2445..2894
                     /locus_tag="LLB18_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245659.1"
                     /translation="MTDIVKIKQSGVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKVKLDGLANITFEKVGTV"
BASE COUNT         1027 a          429 c          665 g          832 t
ORIGIN      
        1 ggatttacga aacaatctgc atgtggaata ttggggaaca ttcaacaaga aacaggagga
       61 acttttgatc ctgatactgt tcaaataggt ggaccagcat acggattagt tcagtgggat
      121 ggttcttcat atcctcttgt tggtccagca acatgggatg gaaaagttta tgttcaaaac
      181 ttatttaatg ctgcaggtat taaagaacca ataacgagct tagatgcaca agttcgattg
      241 cttatttgga catttacaaa tggacaatgg atgggcgtag tacaacctac gacggttgat
      301 ggatttaagg cctgtactga tccaagacaa gcagcatatg cttttgaacg aaactatgaa
      361 cgtccggcag cgacacatcc tgaacgtcaa gattatgcag ttaactggta taacaaattt
      421 aaagatttaa aaccaggagg agctactgga gaagcaggac taaaacattt agagtctttg
      481 attggacaac gaattggcaa tggtcagtgt tatggcttgt ctgcagaata ttcaggatat
      541 ctgggtggtt gtggcatggg tgctggaaca aaatatggtt taactcatgt gataggaaat
      601 acttctgcag catctgatat tggtattgcc tatgattggt ctgctgttgg ttggaaagtg
      661 attcaaaacc ctagatatga tcaattagta gttggtgcaa ttattaattg ggcaagaggt
      721 ggacaagtgg gttcatggtt tgcagacgga acttatggac atactggcgt tatccgaggc
      781 ttagctaatg gtcgtatgca aacttatgaa caaaacacag agttaggtat gatttgtgga
      841 aagttagatc gccagtatta tagtgcaagt gcaatttctt ccattgtcat accaccaaaa
      901 tagggaggtg atttaatggc aaagtggaat gtcatattaa gtacaacaga accctataat
      961 tacgtgggga tgattcaagt tcgacaaggc aataaaaaca ctgaagttat ggaagctaca
     1021 attgtcgaaa atggtcttcc atatgattta tcagaatgta aggtatattt tgaatcagtt
     1081 gttggcggaa aatatccagt ccaattagaa acaagaattg tggatgctaa aaaagggaaa
     1141 atcaaatata tttttgataa atattccatg cagtgtttgc atcgacaaac agccaatttc
     1201 attatattta aaggagaaga cttgattgga acaactcaag acttctccta ttttgtcatc
     1261 aatgctgttt caaaaacaga aggagaaatg ggttcttatt ggcaatcaat tgaagattta
     1321 attgctgata tgacagattt tattaatgaa aataaaggcg attttacgga ctggatgaat
     1381 gaaaggaaag aagaatttga tcgctggaga gaagaacagg agaatagttt ccaagattgg
     1441 agagaaggac aagaatcaga ttatttgtca tggtttgaat caatcaagga tattttgaag
     1501 tctatcgatc caggtggagt aatgttagcc gaattaatgg atgcacgtgt agatcttcaa
     1561 ggtgtacgcc atgaatcgat ttctgaacgt ttcctatccg atctaaatta tttgtatcaa
     1621 aaaatgaaag cagcactttt cacgattgaa tacggtgaaa ttgaagtgac tgatattctt
     1681 caagacgatc tcttttcaga taatcacgaa gtcgaaaaaa ttgaaacagt agaatttcca
     1741 attgaagaag gagctttgat tattgcaact gttgatgatc caaaacagaa tgttttcact
     1801 cttgagaaag ttggggtgat ttgatggtta aagtaaagag aatgatggag actgatgaat
     1861 ctggtgttaa acgtcaattt atgccaatta cacatgtttc tgcagtttta ggcttagaaa
     1921 aaatgatatc aggacaatca aaagttcttt cggttaatgg taaatatggt gcagtcattt
     1981 taacgaaagc tgatttagga ttagagaatg caattactga actaccttat gcaagcgaga
     2041 caagcgatgg tattcttact gctgaaatgt ttcaaaagat cgtaaatgga gaaggtggaa
     2101 catatatttt gccgattgct actcctgaac aattaggagg tataaaagtt ggggaactct
     2161 tagaagttac tgaagaaggt gttttatctg caactaagca aacagacttc aatttctctg
     2221 aagaattaaa gggaaaatta gaatctctaa aaatattaaa agcaggtgca aatatatcaa
     2281 ttgcagaaga tggaacaatt agttctacag gtggtagtgg gactggtggt gttaatcagt
     2341 catatgtaga tcaaaaattc caagaagctg taaatcaagc agaaaattac acaaacgaaa
     2401 gaattccaaa ttttactttt gaaaaaatcg gggaggtata gaaaatgaca gatatcgtaa
     2461 aaataaaaca aagcggtgta caggtttatc cacaaactca ttggaatgct atagaaggca
     2521 aaccaacaac ggtgaaggga gataaaggcg atcctggcca agcagcaaca attaccatag
     2581 gaaccgtttc tagtggttca accgcttctg ttacgaatgt aggaacatca tctgcagcta
     2641 gatttaattt tgttttacca aagggagata aaggtgatcc tggaataaat gccacaacta
     2701 cagctgtagc tacaactaca gcaaatgggt tgatgtcgtc cacagataaa actaagttgg
     2761 atggaattgc agctggagca cagaaaaatc caggtaatgc tacaactacg acagcaggtt
     2821 taatgtcagc aaccgataaa gtgaaacttg atggattagc gaatattaca tttgagaaag
     2881 tggggacggt ttaatggctg atattgttca attaaaagaa gacggagttg ctaaatactt
     2941 aaaaacgcat gta
//
LOCUS       DAFBSV010000142         2922 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.148, whole genome shotgun sequence.
ACCESSION   DAFBSV010000142 DAFBSV010000000
VERSION     DAFBSV010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2922
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.148"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(1365..1883)
                     /locus_tag="LLB18_002705"
     CDS             complement(1365..1883)
                     /locus_tag="LLB18_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HBK5245660.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT          968 a          529 c          413 g         1012 t
ORIGIN      
        1 tttcttttac gttctattca gattaacggg taggcttact gtcttttttg gcaataattt
       61 tgcaatcaag ccatttacag atgtaatgcg cggatacttc tgctaagatt gcaaaaaaca
      121 tatcgaaaag gtaattcata atacaacctc ctccccttgc cataataggc cggggtagca
      181 gacagcataa atattatacc ataactgaaa atttcatttt agtacatttc aatatattga
      241 tgaaccagca caataaaaca tgccatgact aacagaaaaa aacttattaa accagatata
      301 acttgtaaac atccaactat atagaaaacg taaattttct atatagttgg attaagataa
      361 cgactattta ttttatcata tttttactat accctatact tttacttggt atatttatga
      421 ataatcgcaa atttacccct atactactag tttgtaagtt agattaataa aaatactaaa
      481 gttatttgtt cttttattaa atacacctac aacttataaa ttgatggtat ttagataaca
      541 cgaaagaata aaaataacag ctgatagtaa agtttgttga cgattgctac tcaatcgaaa
      601 gtgagttagt gcgtatgaac ttgcttctga aaacttatga aatgaaagac cttttacatc
      661 ttgcagaaat cggtactggg attaaactaa gcaataaaaa ctaatgttcc cctcattctt
      721 tgaacttcta ctatttgatt tatttattct gataaatgac gatttcacct tcaggatctt
      781 caaatcccgt atagaattta tttaagatct cttcagtatc agtaatagga taggcgatag
      841 gccacatacc ctttgatggt tagaataaac tgctcaaaat ctgtatcgta tgttggcttt
      901 agcatattaa caaaggctat ctccaaatta taaaccataa gcgttgaatc gttcttaaca
      961 atttcaattc ttcctaaccc aaagtcagaa gatataatta ccggacttgc cttacccttc
     1021 atgtgggttg ttgagattcc atatttaaag ggaattgtcg gtactatcgg cggtctgaaa
     1081 aacatcccaa aaataaaaaa atctttcccc tgctagtctc ctaagtccct ttgtagcgga
     1141 tatggcacca taatctcatt ttatcgaagt gagtcatggt ttatctgttg gccaaccaaa
     1201 attgatacaa tctaacgatg caccctctac ggcattctag gggagtgcac ttgcattcac
     1261 ccaataaaaa ccggcagtta gcaaagaact tatgtagtcg tatgttctta ctgttaacat
     1321 acaagaggtc tcctttccac aattgcttag cagtaaacgg gaatttacaa agctaatctc
     1381 ttccattttc ttatctttgt tctaaaagtc ccaaatggag caactgtatt tacatgaata
     1441 aatttatata cttcccatac agccgttttg gttgcctcgt ctgcccattt tcttttgtgt
     1501 gcagtgaata gatcttcatc actcattgaa tcaatcatca tgttaatatc atcaatatta
     1561 cgattgagaa tttcctctaa ttctttcaat ggtagatgtg cataggtatt tgtaaaccac
     1621 ttatataact ctcctaactg attccattta aattgatcag aaggcgtttt aacagataat
     1681 ccatttcttt catcattttc ccattttaga attaaattcg tccaaccaac ttgatatgct
     1741 aaattttcag caggtgttct atccacttcc tcaactcttt tatccttcaa ttcttcagga
     1801 atagtttcaa attctaaaat atatttagta taagtcctat ttatttcttt ttttaattct
     1861 tctttatttt tatatgttct cattatatta cctccataaa ttcctaattg tctcctttaa
     1921 ttcatctata atttcatcca cgatatttta atccgttcta caatgcatat ctgatatgca
     1981 ttgactgtct aactcatatg tgaatgattt ataaaatatc ccaacgtctc atctaaagaa
     2041 atgttgatcg tcagcaagga gctaaaaaat acgaatatat ttcttttgta gtaaaatcgg
     2101 actggtttgc atatcatttt cttcgtaaat atcaaaatca tgttaactac tatcaattac
     2161 taataaaaac taccacttta agcgttaaga actgttaagt ttagttaagt gaggatagtt
     2221 cacaaaatcc attgttaaac ttcacgaaag tggtaaaact caaaatgctt tatataggat
     2281 tacagcatcg ctctttcttc gattgcgcgt tgggtaaaaa atattatgaa gtaaaaattg
     2341 acgatgacac gttccttacg gctcatcaga tgaaacagct acaaaaacga aatgatcaac
     2401 tcgaagaaaa tttaattcta aaaaagcgat tgccatattc acgcctcgct cgacgaacta
     2461 ttaaaggtca agatttacct gaagatcatc ctttttagga aattgaagct ttttatgttg
     2521 cacaatgcat ttataatact acaatgatgt tttcaccaga tattcttcta gggtgcggtg
     2581 taatgaaaca gatacacttg caaaagaaaa ttcaccgcga atttactaaa attatgaata
     2641 attatgttaa tcttccgaaa tttttttcca aaattaaggg atcaagctgg tgttatagat
     2701 tgtttaaggt tggcaaaaaa ataacttctt tttaaacaat tatagaaaac cgatactctg
     2761 ttaagttggt tgacacggtg tcgattttta tgactttctt attctgaaac ttcactaacg
     2821 gacagtacct aaaaagtcta tagtatggac gtttacgagt actattttat caaaaatgct
     2881 gctcatttca acttatatgt tttagtgaac tacccccact ta
//
LOCUS       DAFBSV010000143         2918 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.149, whole genome shotgun sequence.
ACCESSION   DAFBSV010000143 DAFBSV010000000
VERSION     DAFBSV010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2918
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.149"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(60..422)
                     /locus_tag="LLB18_002706"
     CDS             complement(60..422)
                     /locus_tag="LLB18_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBK5245661.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            645..1397
                     /locus_tag="LLB18_002707"
     CDS             645..1397
                     /locus_tag="LLB18_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBK5245662.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(1537..2460)
                     /locus_tag="LLB18_002708"
     CDS             complement(1537..2460)
                     /locus_tag="LLB18_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5245663.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(2475..2747)
                     /locus_tag="LLB18_002709"
     CDS             complement(2475..2747)
                     /locus_tag="LLB18_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245664.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT          940 a          557 c          476 g          945 t
ORIGIN      
        1 tttttattgt atacattaga tatggagcag gttaccataa agatgattat tagtcgttat
       61 taaatagaat ccttcgtatt tttttgttct atcactacaa tatctttatt tggacgtttg
      121 aattgtattc cggcacgttc tagctcctgt ttcactccta catggacttt gacatcttct
      181 cgtgtcattt ttaaaacgtg atgaatcgca tagtcgattt cttgccttgt gatttttttc
      241 ttcgtattga tcatcacgac ttgcttttta tcatatgtgt ctaccaatag cagttgtgtt
      301 cgatctaacg aaaataattt gtaataatta atagccgtat tcccaaaaaa gaattccact
      361 actttaggat aaaatgtctt aatatttaaa ttactattca caggtgtttc gattagcttc
      421 atctcattcc tcttttctat atagtcgatt tagatccaat cttaagttat gttaccatct
      481 ttcctagcat taaggaatcg gttacaattg aacctttaaa gacaaaagga tttacctttt
      541 atcacttaat agtataacat aatttcgtga gaaaaaaata caattttttc ttgaccatct
      601 cgttacgtaa aggattatgc ttacatttgt caggaggaaa aataatggag tacacaataa
      661 agaaaatgtc agagatatca ggagtcagtc cgagaacctt gcgcttttat gatgagattg
      721 gactgctaaa accagctagg atcaattctt caggttatcg gatttatggc aaaaaagaag
      781 tcgatcgtct gcaacacatc ttattttatc gaacaatggc attcaagttg gatgatatcc
      841 aagaggtctt agacaatcca tcttttgacc accagaaagc tttaatcaag catcagcaaa
      901 tgttgctgga aaaacgggca caaatcgata ccctcttgac aactgtccaa cagacacttg
      961 atatgtacga aggaggaaga aaaatgagtg acaaagaaaa atttgaaggg tttaaacaac
     1021 aaaagttgaa agaaaatgaa gaatcctatg gacaagagat tcgacaaaaa tacggaaaaa
     1081 aaaaggttac agcatccaat gaaaaatgga tgaatatgga taaagaaacg tatgaagaaa
     1141 tgcaaactgt tgaaaagcag atgttatttg atctcactct ttacttaaaa gaaccagaag
     1201 atgaaagctt agcagaccgt atcttccaag ctcataagaa gtggttctct tacagctggc
     1261 ctgaatatca gccaaaagcg cataaaggac taggaatgat gtacgaagcc gatgaacggt
     1321 tcactgcata ttatgacgag cgaagtggtc atggtgcagc aaaagcttta aatgaaatta
     1381 tccaaaaaaa ggcgtaatct tttacatgat ccaacaaaaa agtacacgta aaatgaccta
     1441 ataacaaaac agcagacacc caagttagat ttttatgcta acttttggtg tctgctccat
     1501 tctttcacaa gttttttcat cctactttaa atatattcat cgttgaataa acgtataagg
     1561 tattttcact ttatcctttt tttctgtaag aaacaattga aatgccattt ctccgcaagc
     1621 ttccagatgg tggtcgatgg ttgggaaacc aagaagctcg ctgatcagca aattatcgcg
     1681 tccaatcacc actggtgtct tatcttgcag atagctttgc aagatgcctg ctgcaaccat
     1741 atccgaattt gtaaagacac catcaactcc aagctcttta aaaaagaagc ctgcttgttt
     1801 tcctttctct gcatctatac aatcccaaaa aacaagtgat tcatcaaaag atggaaaaag
     1861 ttgatgacat agctgcaaag tgatttttga gttataactt agcctgccac ttcgccccaa
     1921 cgtgatgccc aattgcttta taccttgctg cttcaaataa gtaagacctt ctgtaattga
     1981 ttgttctcga tcaataaaga cacagcttgc ctgttttccc ttgatttctt cacaaaaaac
     2041 tagaggtcca tatttttgat atgccaataa atcatctagt gtattggcac gagacgtaat
     2101 gatcaatcca tcgaaagctt tagctgcaaa ttcttcaaga taccttcgct ctttttcttt
     2161 atgatagccc gtcggtaaaa gtgtcacttt gtaatcataa tcaaacgctg cttcaatgat
     2221 cccactgatc aactgatcaa aatacggatg attggtataa ggcagaatca ctccaatgct
     2281 tttcgttttt ccataactta actgtctggc atttgcatta gggatataat cgacttcttt
     2341 catgaccgca agtatttctt tccttttttc ctcatctaca tatggatgtc cattgattac
     2401 acgtgaaata gtagaaactg aataacctgt gagctttgcg atatctcgaa tgtttgccac
     2461 tgctgcttcg ccacctatac aaaaagattt tcttgtaaat agtctaccac agctggaccg
     2521 cattcaaaaa actgatacat ttttccttca tgcgaaaaac tgatccgctg cccgccccaa
     2581 tatatatctt ttgtcaaatt ttcgatttca ttcattggta tttcttttac tatattccta
     2641 ttcaaccctt gaaaactgta caacgttaat acggatccct tgaactcgac aaacgcataa
     2701 aaataattgt tcgttgtgcc atctgttatc tctacataag tattcattgc aagccctcct
     2761 tttgatactt tgagtatagt gtatgaaacg cgtctcatag caaggagttt gttttgccaa
     2821 agaaaagttt tattcctctt tcattattac caaagtctct tattttaaat tgaatacatt
     2881 ataatgatac tgtaaatata tctttattat tagtgaat
//
LOCUS       DAFBSV010000144         2800 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.150, whole genome shotgun sequence.
ACCESSION   DAFBSV010000144 DAFBSV010000000
VERSION     DAFBSV010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2800
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.150"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..209
                     /locus_tag="LLB18_002710"
     CDS             <1..209
                     /locus_tag="LLB18_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5245665.1"
                     /translation="NKGLGQRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGF
                     KKIGIKHFPLGKQDRICPILEKEI"
     gene            complement(206..940)
                     /locus_tag="LLB18_002711"
     CDS             complement(206..940)
                     /locus_tag="LLB18_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245666.1"
                     /translation="MRSSKYTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVL
                     KGIEIGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFA
                     QLSEALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKS
                     AYLYDNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFDDLFALLKAKGVTELAI
                     YQKGKRIMVPLQSKKTSSASKVRTFF"
     gene            1683..2237
                     /locus_tag="LLB18_002712"
     CDS             1683..2237
                     /locus_tag="LLB18_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBK5245667.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
     gene            2491..>2800
                     /locus_tag="LLB18_002713"
     CDS             2491..>2800
                     /locus_tag="LLB18_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245668.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     L"
BASE COUNT         1054 a          365 c          469 g          912 t
ORIGIN      
        1 aaaacaaagg gttagggcaa cggttactcg atgaagcgaa tcgttatgct aaaacgaaac
       61 aaaaacgtta tttacgtttg actgtttatg aaaaaaatca tgcaggtatt cgtttttatg
      121 aacgtcatgg atttaaaaaa atcgggatca aacatttccc tttaggaaaa caagatcgta
      181 tttgtccgat tttagaaaaa gaaatctaaa aaaacgtcct cacttttgat gctgaggacg
      241 tttttttaga ctgtaatgga accataattc gctttccttt ttgataaatc gctaattccg
      301 tcacaccttt tgcttttaac agagcaaaaa gatcatcgaa atggaaacgg aaatgttcaa
      361 ggtaatgccc atctgatcca acactaaaca aggtaccacc acgtgaaaga tataaatcga
      421 tgacatattc atataacgct aaattgtcat acaagtaagc gctcttagca tttaattcga
      481 atgccaattt atttttgatt acttgatcta gaatcggtaa aaactgcgct tcatattgtt
      541 taaattcagc aacggataga ccaaataccc gaaaaccata gtcaaaatga gcaaagacat
      601 ctgcttctat aacaactagt gcttctgaaa gttgtgcaaa atactgagga atcacaatag
      661 caggatccat atctttgact tcgtcatcta aataatcaaa ttgaccatta tgatgcacac
      721 tgagtaattt taaatcgtaa tctttatcgg ctaaatagtc gatgatccga tccttttcag
      781 aagcgatgta accgatttcg atgcctttta aaacacgatt gccaaaacgc ttatttaagc
      841 tatcgattgt ttgactgtac atttcataat cggggatatc atcgacttta gtaacaggat
      901 tggctaagtc aaaatgttca gtatattttg atgaacgcat atgtagtcct catttcttgg
      961 gagatttgag actactatat gcgttttttt gttgatttac caacatgttt agacattttc
     1021 ctctaggaaa aaattaacta gcaccacggg tatactacta tattttaggt ttcatattat
     1081 ataaattaat aatatactac catttgttgg tagtataatt taaaggtaat aagttattct
     1141 tttattacta tgtttgggtt ttatagcaag gaaagtttaa taagagtttg gatctagcaa
     1201 acaatattaa tgaggtcatt aaatcttatt atctttagtg atataacgaa atatctacac
     1261 agacaaaatt atgatcttgc gtaaagttat aaaatatcaa taaaaatatt ttattaatga
     1321 aaagcttggt agcacggtta ttcatatgct aatttatttc actttatagt aaggggagtt
     1381 cttagtatat tgttcaaact taaatttcat ataatttaat tatgtaaatt agctattcta
     1441 agaacttcta cggataattg cccgtctaaa atttaaataa gaggttagaa tcttcatata
     1501 agtaaggtta atttttttgt acaaaaaagt cggaatattc tgagttactg aaatgatata
     1561 aaatcataaa ctaaacccct tgattttctt cacttttaac agagtatata tataagttca
     1621 tgattatggt aaaatatata tataatcatg aactcagaat atttttaaga agggaaacaa
     1681 tagtgagcta taatgtacaa ccgttaagga caaatgaaga gatacaagat tttcagtttt
     1741 ggctaagaag aacaagtaat ccagaaagag atagtttttt atttttgttt ggaatcaata
     1801 atgggttacg tatgtcagat attataggat taaaagttgg agacatacga ggtaaaagta
     1861 agcctattat tgttgaacat aaaacaggta agcgaaaacc gatttttata gataatttga
     1921 gagaagagat tttattatat actgaaggta aagaagaaaa tgattggtta tttccaagtc
     1981 ggcaacaagg tcgacatata acaagggatc gtgtctatca gatatatgca gatatagcag
     2041 aaaaattagg aagagatgat ataggaacac atacattaag aaaaactttt gggtatcact
     2101 actacaagaa aactagagac attgctacct taatgtttat ttttaatcat agctcgcaag
     2161 caattacaaa aaggtacatt ggtataactg aagatgaaat aggggcatcg ttacgtggtt
     2221 ttaaattggg aggctaattg agatattagg atatattttt tgtgtataat gaaaacttag
     2281 aaggtgagat taatgaagat aactgaattt tcggaagtat ttaaaacgtt tagtaacatt
     2341 tacaatagaa taccagagat agaacaaaat gttgtagttg ataatgatta ttatatagag
     2401 aatgatttta ataaaccaag aaaatatgac aacctataca attttataca caatagaaca
     2461 acaataaata acaacagtaa cactcgagtt ttgattaatt cagcatattt tcatattaaa
     2521 tatttaaaga aatatgagta tgaagaagtt gtattagatt atgggctaaa tagacagtca
     2581 tttttaattt atgcaataaa taacggaaat ttgccaagca ataaaaagaa cataattatt
     2641 gaaacatatg cctatctgga ggggggatct aaaaaactaa ttaagtcatg taatatagag
     2701 tatcaattat cagtaggaga aattaaatgt gttttcgaag aagatttaga acttgactta
     2761 aaaaaaattt ttgccagcat tcatgattat ataggtttga
//
LOCUS       DAFBSV010000145         2795 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.151, whole genome shotgun sequence.
ACCESSION   DAFBSV010000145 DAFBSV010000000
VERSION     DAFBSV010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2795
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.151"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            176..583
                     /locus_tag="LLB18_002714"
     CDS             176..583
                     /locus_tag="LLB18_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245669.1"
                     /translation="MSFLLLKYLEIYSVKKNKLIGENDSPIKTPIELSLRNRMGILQR
                     SEIVKELFYHKFSYEIRLDDTYEHYRIVFFVYNSIEDATATTALTFGFTKNGTINSDK
                     TRQAATESDDICKKVCNGEENYWIGEEKLNEIY"
     gene            570..1022
                     /locus_tag="LLB18_002715"
     CDS             570..1022
                     /locus_tag="LLB18_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245670.1"
                     /translation="MKSINDLLKKHPDLYKKLNSEQRNLSKQLLKIRLKKQKNVTEFS
                     KMLGISEKKYLEFEFGDMHIPVAEYNKLLKQVENLSYKDSMNFTIKVAGGPIKYDRIE
                     NKPYIRNKSYSVFKSRKRKEVSSNMVYASVNYQDTSRYIVEKEVYVHG"
     gene            1015..1413
                     /locus_tag="LLB18_002716"
     CDS             1015..1413
                     /locus_tag="LLB18_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245671.1"
                     /translation="MDKGNSVTFALENISLNKIHFELTDNFSYGDLEFNIELGYKEDE
                     AEYLEKKLVSLRAHIVGGMEGAPVDILLFSVIRVSTNEQPYKKLVEESMGELAKPILN
                     KASNLISNLYSEVGVMPTVIDLYQLYSQQK"
     gene            1725..1798
                     /locus_tag="LLB18_002717"
     tRNA            1725..1798
                     /locus_tag="LLB18_002717"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1759..1761,aa:Ile,seq:cat)
     gene            2178..2339
                     /locus_tag="LLB18_002718"
                     /pseudo
     CDS             2178..2339
                     /locus_tag="LLB18_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
     gene            2489..2689
                     /locus_tag="LLB18_002719"
     CDS             2489..2689
                     /locus_tag="LLB18_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBK5245672.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
BASE COUNT         1001 a          393 c          515 g          886 t
ORIGIN      
        1 tatacatctt tcttcattct agtttttgca gcagggattt taaagtagtt cttattagaa
       61 tagtagagat tgattaataa gctatcttcg attgctagaa agaaaacttc tgaatcccac
      121 accttataaa aatctttgat aaatctattc gaaggatcaa atttaaacca taattgtgtc
      181 tttccttcta ttaaaatatc ttgaaattta ctctgttaaa aaaaataaat taattggtga
      241 aaatgattct ccaataaaaa cacctattga gctaagctta agaaatcgga tgggaatact
      301 ccaaagatcg gaaatagtaa aagaactttt ttatcataaa tttagttatg aaataagact
      361 agatgatact tatgagcatt atagaattgt ttttttcgta tacaattcta tagaagatgc
      421 tactgcgact actgcattaa cattcggttt tacgaaaaat ggaacaatca attcggataa
      481 aacccgtcaa gctgctacag aaagtgatga tatatgtaag aaagtatgca atggggaaga
      541 gaattactgg ataggggagg aaaagttgaa tgaaatctat taatgattta ttaaaaaaac
      601 atcctgattt atataaaaaa ttaaattctg aacaaagaaa cctgtccaaa caattactta
      661 aaataagatt aaaaaaacaa aaaaacgtga cagaattctc aaaaatgtta ggaataagtg
      721 aaaaaaaata tcttgaattt gagttcggag atatgcatat tcctgttgca gagtacaata
      781 aacttttgaa acaagttgaa aatttgtcct ataaagattc aatgaatttc actattaagg
      841 ttgctggcgg ccctattaaa tatgaccgta ttgaaaataa accttatatt cggaataaaa
      901 gttactcagt atttaaaagt agaaagagaa aagaagtatc gtcaaatatg gtctatgcta
      961 gtgttaatta ccaagatacg agccgctata ttgtagaaaa agaggtatat gtacatggat
     1021 aaaggaaata gtgttacttt tgcacttgaa aatattagtt tgaataaaat tcattttgaa
     1081 ttaactgata attttagtta tggagattta gagtttaata ttgaacttgg atataaagaa
     1141 gacgaagcag agtatctaga aaaaaaactt gtttctttac gagctcacat tgtagggggg
     1201 atggaaggag caccggtaga tattttactc ttttcagtta ttcgtgtttc tacaaatgaa
     1261 cagccatata aaaaattagt agaagaatct atgggagagc tagctaaacc tatcctgaat
     1321 aaagcttcta atttgatttc taatttatat agcgaagtag gagttatgcc tacagttatt
     1381 gatttatatc agctatatag tcaacaaaaa taaaatacaa gtaatagagt tatctattta
     1441 aatttgcaag acaaagacct caaccagtca tccttggttg aggctttttt gctctgtaat
     1501 taactcgtat agatcctgca agatagtttg tttctgaata aatgattgat atgaagtatt
     1561 tagatgactg tattgacaac tataaaaatc attcgataaa atagtgatgt tatcgcatat
     1621 cttcactatc acccataata gtcacactcc aagctatgcg ataacaggtt tgttgccaca
     1681 cattctactg gttgattgtt tatggcttta tgtggcaaca accagtaccc ttagcttagt
     1741 tggtcagagc agacggctca taaccgtccg gtcgtaggtt cgagtcctac agggtacata
     1801 atttaatcta tttgataaaa aataaaattc aataatggta taataaaata tcggctcgtc
     1861 gcttccacag agattttcgt gggaggaggt gtatgatttg tttgaattca ctttggagca
     1921 cgtgctcttg ccattgttaa ttggtttaac tttggcatta tttagtcatt ggctagataa
     1981 acattagagc cgacaatggc gcttactgtt tcgcagcggt aagcgtcttt ttttgaaaaa
     2041 gaaaaaaaca caacgtattc gcaggtacgt tgtgtttatg gtgtatattt gtttaaattc
     2101 actttcaatt attattatac ttgttaaata aattgtgtca atataaaaga tatttttata
     2161 cgtgtactaa cctatattat ccttctggta atgttattcc atcgcagcag gatatgaatt
     2221 ttaccaaaag gatacaaaag tgtggagaaa tgatggggat cactgtactg gaccacttga
     2281 tcatcggacg caaacgatat tttagtttga gagaagaagg aatgatggaa gagaagtaag
     2341 ttgctttctt gcaaaaaaaa tgaagcaagt gtacaattat attgtaattt tgtttgggaa
     2401 tagaagttga aacatctgtt gcacctctat cgtacacgag caatgttaca atttaaatta
     2461 gtgcttttgg cacgaggagg atattattat ggaaaacgga acagtaaaat ggttcaacgc
     2521 tgaaaaagga tttggattta tctcacgtga agatggaagc gacgtattcg ttcacttctc
     2581 agctatccaa ggtgacggat tcaaaacatt agaagaaggt caagcagtga ctttcgacgt
     2641 tgaagaatca gaccgcggcc cacaagctgc aaacgttgta aaagcttaat tttatctgta
     2701 aatcaaattg atggtagaca tcaattttta cgagagaaca aagcgagtaa caaaaatacc
     2761 tgccacaaga gacaatttct cttgtggcag gtatt
//
LOCUS       DAFBSV010000146         2738 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.152, whole genome shotgun sequence.
ACCESSION   DAFBSV010000146 DAFBSV010000000
VERSION     DAFBSV010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.152"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            179..775
                     /locus_tag="LLB18_002720"
     CDS             179..775
                     /locus_tag="LLB18_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBK5245673.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            899..2698
                     /locus_tag="LLB18_002721"
     CDS             899..2698
                     /locus_tag="LLB18_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBK5245674.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
BASE COUNT          782 a          469 c          516 g          971 t
ORIGIN      
        1 tttaaaaaaa acaagttatt aaataagtct ttagttggat gtttttttga gatcaatctt
       61 ttatacttat gatgaactta caaaattgtt tgttttctgt catatcaaaa aatggcgcag
      121 ttagttgctt ttctagtaaa gtatagttaa caaagaacct ctaaggagtt gatgaataat
      181 gaatattgct gcctctcgaa aactgataaa tttcatatcc attatcggat taggcctatc
      241 aatcgcgctg acgatttatt ttattaattt aggtgttttc aaagatttga atgcgttaag
      301 aggattagta ggtgattcca tcattttagg accgattatt tttgtcttca tccaaatcct
      361 gcaagtagtt attccaatca ttcctggagg gatcagtact gcagctggtg tcctgatatt
      421 tggcccttat gctggattta tctataacta tattggaatc tgcattggtt cgattatcat
      481 ttttctgcta gggcgtcgtt atggaaagcc attcatactt tccatgatta gcgataagac
      541 atataacaaa tatattggct ggctggataa tcaaaaccgt tttgagaagc tgtttgctct
      601 agctattttt cttccagttg ctcctgacga tgcgttatgt ttgatggctg gattgacaaa
      661 catgtcagtg aaacgatata cactaatcat tttgattgct aaaccactgt cgattttctt
      721 atatagtatg gccttgattt atggaggtca atatctaagt ggtcttcttg gataatattt
      781 attttgtaaa attagtcatt gattgacaat gttaaatctg ggaaagggtc tgcaaaacac
      841 actgcaccct ttcctttttc attagatttg cgctataatg tgaagagcag gtgataggat
      901 gaattatttg aaacgtagct taggtaatgc ttgggacttt ttaaaaggaa cacaagctta
      961 tttccgtgat gtcttgctga tgcatggctt tattttattt atttgtttac ccttattgag
     1021 cagtacgacc cgttttattt tacaccgagg ggcaattgac tatttgtctt atgacaatat
     1081 tccttcaatt ttttctcaac atcctggggt tctactctcg ttaatcgtag ttttgatgac
     1141 gattttactg ttagtttatt tcgaatttac ttttcttttg atgagtgttt tttttattaa
     1201 aaagaaagaa ccaatctctt tgaagcaact cttacacttg acgatacttc agctgaagaa
     1261 agtgagaccc attacttttt tgtttttcct tgcttatttt ttattgattc taccgatcag
     1321 cggattaagt tttaattctg atctactgtc aaaaataaaa atccccgctt tcattatgga
     1381 ttttattttt gctaatcgtt ggatcatcgt cagttccttt ttactcgttt atattttcct
     1441 tggctatatt gggattcgac tgatttttgc tttaccggaa atgattctac gggatcgtcc
     1501 ttttcgagca gccattcggg aaagctggtc attgaccaaa tcgcgtcttt tggccatcac
     1561 gggccaattt attgtgattg gcggtacgat tttactcctt tcttctttag gatatatcgt
     1621 tgttattttg gcacaaagta tggttgaaca atttttccca gactatgcat tgatcagcgc
     1681 tgtgtttgct atgacgcttt tacaagggat tttattattc aatatcgtga tgtctaccgt
     1741 agggattttt tatatcattg ttgatttcat ggatgacgaa ggcttcttgc ctgagatccc
     1801 taagtggttt atcccacaag cccccaactt gcgtttctct gcgctgaaaa acactggttt
     1861 gactcttttt gcagtttttt tcggtattgg cgtctgtctt tacaatatgg attatctgac
     1921 ttcagctgtt cagacaaaac cagtgactgt ctctcacaga ggtgtgagta cccaaaatgg
     1981 ggcgcaaaat actttagaag cacttgaaaa aacaagcaga gactatcatc ctgattatgt
     2041 agagatggat gttcaggaaa caaaagatgg tcatttcgta gtgatgcatg atgcaaatct
     2101 tcgtcactta acaggggtaa atggaacacc acaggatctt acattgaaag aattgacaaa
     2161 tcttacagtt actgaaaacg gagtgcaagc ccctgtttgt tcttttgatt cttatttgga
     2221 aaaagcacat aagctaaacc aaaaattact tattgagatc aagacctcta aaaaagattc
     2281 ggatgacctt gtcgaacgat ttgtccataa ataccgcaaa gttatcttag agaaccatca
     2341 tattttgcaa agtttgacgt accaaaccgt ttcagattta aaagaagcag aaccaaactt
     2401 ttatgtgggc tacatcttac ctttcaatat tgttgggccc cctgtgacgc ctgctgattt
     2461 tctgacaatg gaatatagta cgatcaaccg taacttcatt aattctgccc accaagacgg
     2521 aaaagaagta tatgtatgga caatcaacga ttcagatgct atgagtcgca tgatgtttta
     2581 tggtgtggat ggtatcataa ccgatgagat gggactacta aatgaaagtg tgaaacaaac
     2641 agatgaagaa atcacttatt cagataaact gctaaatttt gttttgggag tcggctaatc
     2701 aaaaatcgtt aatgaaaaaa gtctttatac aacaaaaa
//
LOCUS       DAFBSV010000147         2728 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.153, whole genome shotgun sequence.
ACCESSION   DAFBSV010000147 DAFBSV010000000
VERSION     DAFBSV010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2728
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.153"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..945
                     /locus_tag="LLB18_002722"
     CDS             <1..945
                     /locus_tag="LLB18_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBK5245675.1"
                     /translation="NRSNADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYAWK
                     EKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSDADKYNPEGQKVTTDLNKEP
                     DASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVTYPDGSKEEVEVTISVVDKK
                     APNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHGTADKNGNFTVKVPKLEAGT
                     KVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTDNQGSNSNQDKNRGKSQSSK
                     VFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1079..2422
                     /locus_tag="LLB18_002723"
     CDS             1079..2422
                     /locus_tag="LLB18_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBK5245676.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            2534..>2728
                     /locus_tag="LLB18_002724"
     CDS             2534..>2728
                     /locus_tag="LLB18_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBK5245677.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSES"
BASE COUNT         1091 a          354 c          499 g          784 t
ORIGIN      
        1 aatcgttcta atgcagataa atacaatcct gaaggacaaa aagtgactac agacttaaat
       61 aaagagccag atgcatctga gggaattaag aacaaagaag atttaccaaa aggaactact
      121 tatgcttgga aagagaaagt agatgttagc acagctggaa ataaaaaagg tactattgta
      181 gtgacatatc cagatggatc atctgatgaa gttgaagtag acgttacagt gacagatact
      241 cgttccgatg cagataaata taatcctgaa ggacaaaaag tgactacaga cttaaataaa
      301 gagccagatg catctgaggg aattaagaac aaagaagatc taccaaaagg aactacttat
      361 acttggaaag aaaaagtaga tgttagtaca gctggaaaca aaaaaggtac tgtagtagta
      421 acatatccag atggatctaa agaagaagta gaagttacta tttctgtagt agataaaaaa
      481 gcaccgaata aacctcaagt tgatcctatt acagagggtg accaaattgt tactggtaaa
      541 actgaaccaa atgcagaggt gacagttaca ttaccagacg gaagtcaaca ccatgggaca
      601 gctgataaaa atggtaattt tacagttaaa gttcctaaat tagaggcagg gacaaaagtg
      661 atagtaactg caactgatga atctggtaat actagtgaac ctactaatgt agttgtttct
      721 tccaacaaaa aagacagtgg aaaaaacggt agtaaaggta gtaagactga caatcaaggt
      781 agcaacagca atcaagacaa aaatagaggc aaaagccagt cctcaaaagt ttttcctaag
      841 acgggagaga gtgacagtaa tatctttact attagcggtg gtttaatact gttaggaacg
      901 ttaggattat tagggtataa aaatcgaaaa aaagagaatg aatagaaaat caatttctta
      961 agtcttctct gagaagagga agaatctttt tcttcctctt tttgcttttt tatgatggga
     1021 aataagtgtt agttaaagat gaatatactt tttatagaaa ggaaaagaat gtaattaagt
     1081 ggaaaaaata gtaattattg gttcaaacca ttcagggcta gccgcagctc gatttctaaa
     1141 cttaagcgat tcaaattatg aagttattct aatcgataaa aaatcagaaa ttagttactt
     1201 ggaatgtggg acatcgttat ttataaaagg agaagtaagt aatttagaag atctttttta
     1261 tcaaaataga atgacactaa attctgagat aaaaaagtta tttctagaga cagaagttga
     1321 caaaattgat attcaaaata aaaagattag ttgtgtaaaa aaagatggta caagattctc
     1381 tcaagaatat gacaaagtta tattagctac aggttcaaag caaattatgc tagatatacc
     1441 ggggaataat ttagctaata ttttttcgat aaagaatttt ccaaatgcaa aagagatttt
     1501 taaagctttg gatgatagta ctattaaaaa agtaggaatt attggagcag gatatattgg
     1561 agttgaaatt gctgaagcca taagaaaaag agggaaagaa gtatatcttt tcgatgttgc
     1621 agatagagtg ttgtcgactt attacgaccg tagtttttca gataaagttg aagaaatact
     1681 atcaaaaaat ggaatacatc tttgtctatc agaaagtcct aaaaaatatt taggaagaaa
     1741 aaagattgaa aaaatagtca ctacaagtgg tacccaatac tctatggata tggtcgtaca
     1801 agctatagga tttctatcta atagtccaat tggggaaaag gaactcttga gagatgttag
     1861 tggagcatat ctaactaatg aataccagca aacaaatata aaagatatat atgctattgg
     1921 ggattgtgct acaacttttt ttacgtccat taatagaagt agtgttgatt tttctatttc
     1981 taatgctcta agaacagctt atattgcaac tcaacatatt aacaatcaag attttacacc
     2041 ttctggttcc caatttacaa atggcttttc tatatttaat tacaattttt acgcagcagg
     2101 tttgaattta aaaacagcac gattattaag tgagtctata gattatatag aaatagaaga
     2161 tttcattaga cctgcttttt tgagaaaaaa tagtcgtgta aaattaagaa ttagctttga
     2221 aaaaaataca aagagaatag taggtgtaca actttgtagt caagaagatt tatctggact
     2281 attatcaatg ttttctcttg ctatagaaga acaaattaca ttagacaaat tgaaaatgtt
     2341 agattattta tttcatccta gttttagcca accctataat tttattttaa aggcagtaac
     2401 aggattaaac attgaaacat aatcgttact aaatgaaatc aagaaatata ctgtattact
     2461 caattcattg aaaatattta tcataatttt taatagaaaa cactattaaa gagaaaaaag
     2521 agaggtaaat caaatgaaaa aatctttaaa acttgcatca gcagttatat taatgtccca
     2581 actccttata gcaacacctt tccatgtgtt ggcaagcgaa aattcaacat acaaaattgc
     2641 aaaagaaaga accgagacga ctgaaatgag taattccgat gtaacagcag agagtagtga
     2701 acttttgaca acttcatcaa gtgaaagt
//
LOCUS       DAFBSV010000148         2691 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.154, whole genome shotgun sequence.
ACCESSION   DAFBSV010000148 DAFBSV010000000
VERSION     DAFBSV010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2691
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.154"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            83..1255
                     /locus_tag="LLB18_002725"
     CDS             83..1255
                     /locus_tag="LLB18_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HBK5245678.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
     gene            complement(1385..>2691)
                     /locus_tag="LLB18_002726"
                     /note="aph(2'')-Ia"
     CDS             complement(1385..>2691)
                     /locus_tag="LLB18_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HBK5245679.1"
                     /translation="LKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYP
                     KTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRA
                     YQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSI
                     EIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYS
                     YISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECT
                     IDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNH
                     LLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKA
                     KEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          937 a          474 c          337 g          943 t
ORIGIN      
        1 tgtaaaagta aaaaggccat ataacagtcc ttttacggta caatgttttt aacgacaaaa
       61 acatacccag gaggactttt acatgaccca agtacatttt acactgaaaa gcgaagagat
      121 tcaaagcatt attgaatatt ctgtaaagga tgacgtttct aaaaatattt taacaacggt
      181 atttaatcaa ctaatggaaa atcaacgaac agaatatatt caagcaaaag aatatgaacg
      241 aacagaaaac cgacaaagtc aacgaaatgg ctattatgag cgcagcttta cgacacgtgt
      301 aggcacgcta gaattaaaag tacccagaac acgtgatggc catttttcac ccacagtgtt
      361 tgaacgttat caacgaaacg aaaaagccct catggcttca atgttggaaa tgtatgtatc
      421 aggcgtttca actcgtaaag tatcaaaaat tgtggaagaa ctttgtggta aatccgtctc
      481 taagtccttc gtttctagct taacagaaca gctagaacct atggttaacg agtggcagaa
      541 tcgtttatta tcagaaaaaa attatcctta cttaatgacc gatgtactct atataaaagt
      601 acgagaagaa aatcgagtac tctcaaaaag ctgtcatata gcgattggaa taaccaaaga
      661 tggcgaccgt gaaattatcg gcttcatgat tcaaagtggc gaaagcgaag agacctggac
      721 aacatttttt gaatacctaa aagaacgcgg tttacaaggt acggaactcg ttatttctga
      781 tgcgcacaaa ggattagtct ctgccattag aaaatccttc accaacgtaa gttggcaaag
      841 atgccaagtt cacttcctaa gaaatatctt taccaccatt cctaaaaaaa attcaaaatc
      901 tttcagagaa gctgttaaag gaatttttaa gttcacagat attaacttag cgcgtgaggc
      961 taaaaatcga ttgattcatg attatatcga tcaaccaaaa tattcaaaag cttgcgcatc
     1021 attggatgat ggattcgaag acgcctttca atataccgta caaggaaatt cccacaatcg
     1081 actaaagagt accaatctaa ttgaacgact gaatcaagaa gtacgcagaa gagaaaagat
     1141 tattcgcatc ttccccaatc aaacatcagc caatcgctta attggagccg ttcttatgga
     1201 cctacatgat gaatggattt attcttcaag aaaatacatc aattttgata agtagaaatg
     1261 gtaaaaacat tgtatagcat tttacacagg agtctggact tgactcactt cctttattat
     1321 ttttcatttt tttaaactat ttaatactaa tgtcttttat aatagctttt catatattat
     1381 ataatcaatc tttataagtc cttttataaa tttcttttct accattttcg ataaattcct
     1441 gtttaatatt tttaattcca taaacaatag tttcaatagg ataatattct tcaactatat
     1501 cttgatattc ttttgctttc tcaatatcta tatttccata cattcttaat atatcttctc
     1561 caaaatttgt tcctatttct tcttcactat cttcaagtaa gtatataaaa tcacaatatt
     1621 catctataat tccagaatct ccaaaatcaa ttattccagt taatctatta ttgccatcta
     1681 acaatagatg attacaacta aaatcattat ggcataaaca ctttttaccc tcaaaaactg
     1741 ttgttgcatt tagtctttcc ataaaacttt ctatataatc tttttctata tcagttaaat
     1801 cattataaat agtttcacgc aacaatatat actcttctaa tacattttgt ttattatcaa
     1861 tagtacattc actaatatct gtataatcta aaccgtgcat ttgtcttaaa aaactggcaa
     1921 tatctcgttt taacaaattt tgttcttctt ctgacatagt agaataaatt tctggtgtta
     1981 aaaaagttcc tttaatttct ttataaccta gtatagataa ttcatcacta atatacgaat
     2041 attcaatatt aggaattttt acattagttt ctaaatttgt atttaaaaaa ttatatattg
     2101 ctttttcttt tgcataacct tttttcttat tagtactaaa ttttgtttta aaaatgtatt
     2161 cattattaac taaatatgcc acactatcat aaccactacc gattatttca atactatcta
     2221 ctttgaaatt atcaaagtaa tgctcaatta aatatttcat tgccttaaca tttgtggcat
     2281 tatcatcata tctatattcc attaaataac aatcttcttt tttgccctcg tgtaattcat
     2341 gttctggcaa atcttcaata attctaaaac cagatttttg gtatgccctt attgctcttg
     2401 gattattttt atgagggtct aaaataactg cattagcatt tctttctttt ttcaaaaatt
     2461 caaaaatcaa tttaatatat cttgtaccaa ttcctttact ccaataattt ggctctccta
     2521 taaattgatc cataccatag actatctcat cagtttttgg ataatgataa tcagtatata
     2581 actcatcata cattttatat atttgtccat atccaatagg aacattgtta tattcaataa
     2641 ttactctaaa aacttcatct tcccaaggct ctgtataatg tttttttaat g
//
LOCUS       DAFBSV010000149         2639 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.155, whole genome shotgun sequence.
ACCESSION   DAFBSV010000149 DAFBSV010000000
VERSION     DAFBSV010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2639
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.155"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            112..1311
                     /locus_tag="LLB18_002727"
     CDS             112..1311
                     /locus_tag="LLB18_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBK5245680.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(1338..2606)
                     /locus_tag="LLB18_002728"
     CDS             complement(1338..2606)
                     /locus_tag="LLB18_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HBK5245681.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
BASE COUNT          790 a          573 c          469 g          807 t
ORIGIN      
        1 ataagaaaaa catctttcca tcggaaagat gtttttttgc tttttctagt ttaaataaca
       61 gcttttttca tctattttcg ttatactgta taagaaaaag gagttgaatt tatgaatcta
      121 accagagatc tgatcttttt agttctctat cttattgggg tattctctat cgtttattgg
      181 cgaaaacaga agaaggatcc ttccttgttc ttttacggca gtacgtggac atttacggta
      241 atcttaactt attttgtcgt gttggaaatt ttttattcga ccttttattt tttgattcca
      301 ttgttgttct ttagtatctt tgctttttct tatttcacag aaaaacgaag gctactgaat
      361 ggtcttttat tcaatgtttt actcatcagt ttcggcatct acttgtttgt cttgctgtat
      421 gaaacgcaaa atatttttct tggcggactg atcgccttga tcacgattcc attgctactt
      481 gtccttttat ttggtattta tggattgatt gtttttcttt tttggaacgg ggtcacagtt
      541 ttacgtagag aatcgcattc attagctaat cttttaacgt tgatactagc catttttctt
      601 acactgtttc ttgtttttga ctttttcttg ttaaaatatt tgccgcaatg gataaatgct
      661 ttgtttttct gcgttcccct gatcttgatc tatctattta tcgtattcta caactttttg
      721 actgtctcat tcttgtatca gttcaaccgg cctcgataca atcaagactt catcgttgtg
      781 ttaggcgctg gattgatcaa tggagaaaca gtttctcctc ttctagccaa gcgaatcaat
      841 aaggcaattg ctttttatcg ggctcaaagc cgtgctacat taaatccgcc catcttattg
      901 atgtctggcg ggcaaggagc agacgaaaaa gtaccagagg ccattgcgat gaaacaatat
      961 gccatggaac aaggaatccc tgaaagagac attcttgtcg aaaccaattc gacaaccact
     1021 ttggaaaaca tgctctattc aaaggaaatc atggatcagc aaatgaaagg gccataccgc
     1081 gcgatcttta gttccaacaa ttaccacatt tttagagccg gtctttatgc gcggcaagcc
     1141 aaattgaaag caaatggtat tggtgcaaaa acagctttct actacttgcc taatgcgttt
     1201 ttaagagaat acctcgccat cttgatgatg aacaaaaaaa gacatatgat catttgcgga
     1261 ttgcttttcg caggctccgc attcttatcg ctgattactt tacttttcta aaaaaacaag
     1321 gtgtgacaaa acatatgtca caccttgttt ttttctttca ttctcttaac tattggcaaa
     1381 aagagtatcc cttttttgac cgctacttgc tgagcagaat aaataccgct gttgcctgaa
     1441 cacataaagc tgatcaagca gatcataaag aagtatactg ccgcttgtga accgaacaat
     1501 tcgatcccca tcacaaagca ggcaatcggt gtatttgtcg caccagaaaa tactccgata
     1561 aagcccaatc ctgcaagaaa aggaacagaa acatggagca aaggcgctag tgctgcacca
     1621 agcgttgcac caatttcaaa caatggtgtc acttctcccc cttgatatcc cgcgcctaaa
     1681 gacaaaactg tgaagaataa cttcccaata aaatcataga catgtgcctg tccattaaat
     1741 gattcttgaa gtaacggaag actcaatccg agataacgtt gtgtttgcaa aatcaatgct
     1801 gctgccacaa ctacagctcc acctatcgta tttcgacaaa caggatgagg aatccattgt
     1861 gcatatcgcg cttttaaaaa gacgatcgaa cggctgaata cccaaccaat caaaccaaaa
     1921 gcaatcccag caacaaaaac tttgaagaac agcaacatac tccattcagg aatcacaccc
     1981 atttggtaat gtagatgaga aacaccatag ctttctgtca tgaaatttgc aaacagtgca
     2041 gcaaagaagc tagggaagat cgcttctgtt cggactttcc cgattgccaa cacttctaat
     2101 ccaaataatg ttccagctaa aggtgtgcca aatacagaac taaaacccgc actgattcca
     2161 ctgataatca agatttcccg ttctgattta tccaatcgga acaaacgtgc cgtattatct
     2221 gctaacgctc cccccatttg gactgctgtt ccttcacggc caacagatcc cccaaataaa
     2281 tgggtagtta tggttccaaa cagtgtaagt ggaataagcc gcaacgggat tttttcttct
     2341 ccaccatttc cttgatcgat cactaagttg tttccacgac tagaaagtcc gccgtgatac
     2401 gcatagagat aagcaaaaag cgcaccacta actggtagta gacaaaggag ccaaggatgt
     2461 gatagtcgga tatctgtcac aactgtcagg ctatttaaga aaaaagcaga caagctcccc
     2521 atgaatatac cgagaatcgc tgtgatcacc agccacttca gcatatacac taaaatgcgt
     2581 actggactcg gtaattgttt ttccataaaa aattcctcct caataaaaaa acgcctact
//
LOCUS       DAFBSV010000150         2631 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.156, whole genome shotgun sequence.
ACCESSION   DAFBSV010000150 DAFBSV010000000
VERSION     DAFBSV010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2631
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.156"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            2..1147
                     /locus_tag="LLB18_002729"
     CDS             2..1147
                     /locus_tag="LLB18_002729"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HBK5245682.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            1318..1776
                     /locus_tag="LLB18_002730"
     CDS             1318..1776
                     /locus_tag="LLB18_002730"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBK5245683.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            1935..2405
                     /locus_tag="LLB18_002731"
     CDS             1935..2405
                     /locus_tag="LLB18_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HBK5245684.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(2458..2573)
                     /gene="rrf"
                     /locus_tag="LLB18_002732"
     rRNA            complement(2458..2573)
                     /gene="rrf"
                     /locus_tag="LLB18_002732"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          860 a          504 c          496 g          771 t
ORIGIN      
        1 catgcacatt caaacaaaat tgatccacgg aggcatcagt gaagatccca caacaggagc
       61 tgtcagtgta cctatttatc aaacatccac ttatcggcaa gatggcgtcg gccagcctaa
      121 acaatatgaa tattcaagat ctggtaatcc tactcgtttt gcattggaag aactgattgc
      181 tgatttggaa ggcggtgttc gaggattcgc tttttcttct ggtctttctg ggattcatgc
      241 cgttttttct ctttttcaag ctggcgatca tatcttatta ggagatgatg tctatggagg
      301 aacattccgt ctatttgaca aagttcttac taaaaatggt ctcgagtaca cgatcataga
      361 tacgagtaat cttgataaaa tagaacaatc catcaaaccc aatacaaaag cactttatct
      421 tgaaacacct agcaatccgc ttctaaagat tactgattta gaaaaaagtg ccactctggc
      481 tcatcaacat ggattgatag ttattgctga caatacattt gctactcctt attttcaaag
      541 acctttagat ctcggttctg atatcgttgt ccatagcggt accaaatatc taggcggaca
      601 cagcgatgta gtagctggtt tagtgacttc taaccataaa gatctagccg atcagatcgg
      661 attttaccaa aatgctatcg gagccgtact tggtccccaa gatagctggt tacttcagcg
      721 cggaatcaag acactaagtg ttcgtatgga ggaacatcaa aaaaatgctt ttgtggtagc
      781 tgattttcta ttttctcatc cagcagtaga aaaggtctac tatccaggat tacccgatca
      841 tgaactccat ggagttgcta agcagcagat gagcggcttt agcggaatga tttcttttac
      901 tttaaaaaat gaagaatctg ctattccatt tgttgaatca ctccaactat ttactttagc
      961 agaaagttta ggtggcgtag aaagtttagt ggaaattcct tctgtcatga ctcatgcgtc
     1021 tattccaaaa gaaaaacgag aagaggctgg cataaaggac ggcttgatcc gtctttctgt
     1081 aggaattgag tatggtcagg atctcataaa cgatttagct caggcatttg acagaatcaa
     1141 gaactagaag tcccaataaa cgacttagca gaaaaatcta aaaaatattt cagattgcta
     1201 caccttggaa acgataagtg ttagaatcaa gtagaaagac gtttttgtaa atttcactaa
     1261 ataattcttt agtgaaaagc atcaaaacga atgaacaaac agataggagt cttacaaatg
     1321 agaatgaatg tcgaaagttt taatcttgac catacaaaag tcaaagcacc ttatgtacgt
     1381 gtagctgatc gaaaaacggg tgcgcatggc gatgtcatca ttaaatacga cgtccgcttt
     1441 aaacaaccaa ataaagaaca catggacatg ccaagtctac attcacttga gcacttgact
     1501 gccgaactaa tccgcaatca cgcagattac atcgtagact ggtctccaat gggatgccaa
     1561 acaggctttt acttgactgt attgaatcat gaaagctacg aagacatttt agatgttctt
     1621 gaagcaacaa tgaaagatgt tcttgaagct actgaagtac ctgcaagcaa tgaaacacaa
     1681 tgtggctggg ctgccagcca tacactagaa ggtgcacaag ctttggctcg tgaattttta
     1741 gcaaaacgcg atgaatggtc tgaagtagaa gcatagtttc taaaagaacg taaagatgag
     1801 aagcaatata gctatcttat cttcgtattt tattaaatat ttattgtctg aaaagagttc
     1861 taaacgggaa aacaaatagc tagttttcag tttagcgctc tttttattat ataaaataga
     1921 aaggagaaaa ctttatgtct atttataatt ttgaaactac tttagaagac ggcactgtct
     1981 attcattgaa aaaatatgca ggcaaaccga taatcattgt taacactgca acaaaatgcg
     2041 gtctagcacc tcaatttaaa caattagaag aactttacca agcttatcag acacaaggtc
     2101 tggttatctt aggctttcct tccaatcaat ttaaacaaga gctagattca gcgactgaag
     2161 cagcagaagc ttgtaaaacc acttatggcg ttaccttccc tatgcatcaa ttgattgacg
     2221 taaatggaga aaatacagat cctcttttta cttatcttaa aaatgaagct cctggtactg
     2281 tcactaaagc aataaaatgg aattttacta aatttttgat tgatagaaat ggcaaagtaa
     2341 tcgaacgatt tgcaccacaa acttctccat tgaaaatgac cgctgcaatt gaatccgttc
     2401 tttaacttaa taaaaataaa aaaagatgaa ctatttctag ttcatctttt tgcctttgcg
     2461 tggcgacgtc ctactctcac aaggggcaac ccctcactac aatcggcgct aagaagctta
     2521 acttctgtgt tcggcatggt tacaggtgta tccttctcgc tatcgccacc acactgtggt
     2581 gttatctttt attgagtaaa ttttgttcac tcaaaactgg atttgaagtc a
//
LOCUS       DAFBSV010000151         2397 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.158, whole genome shotgun sequence.
ACCESSION   DAFBSV010000151 DAFBSV010000000
VERSION     DAFBSV010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2397
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.158"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            206..2068
                     /locus_tag="LLB18_002733"
     CDS             206..2068
                     /locus_tag="LLB18_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBK5245685.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2068..>2397
                     /locus_tag="LLB18_002734"
     CDS             2068..>2397
                     /locus_tag="LLB18_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBK5245686.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          864 a          353 c          466 g          714 t
ORIGIN      
        1 aaaatttgaa aaagcgtttg attatttata ttacgactta gtgcaataaa aaacgctttt
       61 taacagtaca tgtagtcgtc tttataatag ataaactctg taatattagt taaaaagcta
      121 taagttgcac ttagttaagt gcaaacattt catattgtcg ttagtttaga aaacgcttat
      181 attagcaatg taaggagaga tgataatgca gcagctaaca aaaagagaaa ggcagctttt
      241 gatttacttg gtggaaatgt ctgaaccggt aacaatcaaa aagttggctg aaaaagaaaa
      301 tgttagtgtt cggacgataa aatacgatct agatgatata agagagtggc tgaatgagcg
      361 gaagcaagtc ctatatagca aacgtagtca gggaatttgg atgaatatta gtagctctga
      421 tcgaatcaaa ttaaaaagcg aattgatgga tgttaatcgt tttgaaatat ttgcagatca
      481 aagtctccga atcaaacgtt tactaattat gcttttagta acaaaagaag ctattactgg
      541 aatgaaaatg gccaacgcat tagatgtcag caaagatacg atcatgaatg atttagatgt
      601 gctggaaaat aattttctta aggaaggatt gaccttgaat cgtcaggcgc gaaagggttt
      661 ttggatcata ggagaagaac gtctagttcg attaacgatt gaagagattc ttcaaaaaga
      721 gttcacggat tatgacattt ataaattaat gtcattgtta ttgaatggcg gtgagactga
      781 atactttgaa atgtattctg ctactgctac acctatccaa gaggtattta atcaagtaat
      841 cattcgaatg cgacacttac tggaatttga aaatctagag aaactgaatt acgcggaatt
      901 actaaatatt ctgattcgag tgacaattgc taccgttcgc ttacgcaaag aggctacgat
      961 tggtcgttat caattggttg ctgaacaaga attagacaaa aacgatcttt cttatcgcgt
     1021 catgcagcag gtctttgatt attatcagtt gccactgttc gaggatgaat atcattatat
     1081 ctatagtgat acattcgaca cgattcacca gcaagacgtc atgaaactag ttgagaatgt
     1141 gatttataaa gtaagtaaag caatcaacca ttctttttat caagatccac aattgttgac
     1201 gaatctgtat gctcatttat ccatgcgatt atcgagaaag aaaaaatttg tcaatgaata
     1261 taatcctttt aaagaagata tcaagcagaa atacccggaa ttatttgatg cgatcaagca
     1321 agcagttcga caagaaataa gtgaacaaaa tattctgatc aatgattctt tcgtggcata
     1381 tattgcctta cactttttgg tttcctacga aagagaagaa gatctacgaa gcgttagagc
     1441 cgtctacatt tgttcaacag ggttgggtgt gactagtctg atcaagcaaa agatcaatga
     1501 agaattaaat aatatcacta tcgtggcatt tgcttcagta ttgaatgcgc aagaaatgat
     1561 tgctaccaaa gatcctgatt tggtgattag tatttttcca attaatggca tcgatcgtcc
     1621 tttcatcaaa gtccatccat tacccactga acaggacttg aaaaaaattc aacaaataat
     1681 aaaaaaaata cttgcttctt ccaatcagca ggaaaggcat aacttgaatc ttagagaaac
     1741 gtccatcaat aaagatactt tagaagactt tagcaaggaa ttgattttga aagcttatac
     1801 gatttatgaa cgtttacttg tcattttgga agcagaattg atccaagaat atcgagaagc
     1861 ttttttgctt catgtattct taatggttca tcgtatcaca tttgatcaac aatatatggc
     1921 agaaggtcgt caagtagacc agattatttt agacaaagga acactggtag gaaaaatcga
     1981 agcagttttt gcagaaaata atttaggaat caatcagtca gaaatcagtg cattattctc
     2041 atatataaaa gaaggagcgt caagttagtg aaaatgtcag acgaggcttt aaaaattatc
     2101 gaggaaagtc aaaatcggga aaagttaaaa caagtgattg atctaattga agagcgatta
     2161 gtagaacatg ctattgtacc aaccgagttg cagtggacca ttctaattaa tcacttgaat
     2221 gagatgctga aacgttctca aagaaaggaa acgattcccg tagtcgatcg ggatttgttc
     2281 aaagaagtat ccaaagaagc cataactatt tctgatgaaa tagttagaag tatcggtaat
     2341 ttaaccgatg atgaaatata tgttttgtcg attcattttg aaacagcaaa aaataat
//
LOCUS       DAFBSV010000152         2303 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.159, whole genome shotgun sequence.
ACCESSION   DAFBSV010000152 DAFBSV010000000
VERSION     DAFBSV010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2303
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.159"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..457
                     /locus_tag="LLB18_002735"
     CDS             <1..457
                     /locus_tag="LLB18_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5245687.1"
                     /translation="IAQNLRQGKKNATEKEMEHASSIAQAKEFIEKLSDRYEAPIEER
                     SSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREALDRDLKGTTTIVI
                     AQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQKGTEE"
     gene            460..2232
                     /locus_tag="LLB18_002736"
     CDS             460..2232
                     /locus_tag="LLB18_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5245688.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
BASE COUNT          755 a          393 c          504 g          651 t
ORIGIN      
        1 gattgctcaa aacttgcgcc aagggaaaaa gaatgcaaca gaaaaagaga tggaacatgc
       61 ttcttctatt gctcaagcaa aagaattcat cgaaaagtta tctgatcgtt acgaagcacc
      121 aatagaagaa cgtagcagta acttttctgg tggtcaaaag caacgtttat ccattactcg
      181 tggcgttatc ggtaatccaa agatcttgat cctagatgac agtacgagtg cactggatgc
      241 tcgctctgaa aagctggtcc gagaagcact cgatcgagat ttgaagggaa caacgacgat
      301 tgtcatcgca caaaaaattg cttctgttgt caaagcagac cgcatcttag tattggatga
      361 aggcagatta gtcggcgaag gaacccatga ggaattggta gctggaaacc gtgtctatca
      421 ggaaatcttt gaaactcaaa aaggaacgga ggagtaagta tgactgatct aataaaagca
      481 agtaaatttt tctatcacta tttgaagcgg tacaaactct cctttttctt tatctttatc
      541 acagtgatca ttgctaccta tctacaagta aaggcacctc aatacatcgg ggaagctttt
      601 caagaattag ctaattacgt aggaggcttg atgcaaggcg tagacgataa aagcaaattt
      661 gtttctgtaa tatggaaact cttgctgttt tatgtactag ctagtgcagc caactttatc
      721 tatagtattt tgttcacaca agtagtaggg aagtcaacga accgaatgcg tatcggtcta
      781 ttcaacaaat tggaaaaatt gacgatccgt ttctttgatt ctcatcaaga cggtgaaatt
      841 ttaagtcgtt ttaccagtga cttagataat attcaaaata gtttgaacca agctttgctt
      901 caagtcatca cgaatgctgt tttacttgtc gggatcttga tcatgatgtt ccgccaaaat
      961 gtagagttag cttgggctac aattgcttcc actccagtag ccgttttgat agctgtcttg
     1021 attatccgca aagcacggaa atatgtggat cttcagcaag atgaagtggg gaaactaaat
     1081 ggttatatgg atgaaaaaat cagcggacaa cgtgtcatca tcacaaatgg cttacaagaa
     1141 gaaacgattg aaggattctt agagcataat caaagtgttc gcgaagcaac cttcaaagga
     1201 caagcttatt ctggtctact atttccgatg atgcaaggaa tgtcactggt caatacagcg
     1261 atagttatct ttttcggcgg ctggttagca ttaaatggtg atttggaacg ttcggtggca
     1321 ttaggcttag ttgtgacatt cgtccagtat tcacaacaat attaccaacc actgatgcag
     1381 atttcatctg gatacagcat gatccaatta gcgattacag gggcaagacg attgaatgaa
     1441 atatttgatg aaaaagatga agtcaaacca gaaaacggta aagcatttga tggtgttgaa
     1501 aaaggtcttg cgttgcagca cgtagatttt ggttattctc cagaaaaact agtcttgaaa
     1561 gatgtctcga tcaatgtgga caaaggagaa atggttgctc ttgttggtcc aacaggatcg
     1621 gggaaaacga cgatcatgaa tctgctaaac cgtttttacg atgtcaatga tggttcagta
     1681 gtcatcgatg gaatagatat ccgagattat gatcttgatg cattacgtag acatgtagga
     1741 atcgttttgc aagaatctgt attgttctcc ggaacgatca aagacaatat cacattcggc
     1801 aaaccggacg cttcagatga agaagtcatc aatgcagcaa aacaagcgaa tattcatgac
     1861 ttcatcatga cgttagaaaa aggttatgat acagagatat ccgaagaaaa taacttattc
     1921 agtacaggtc aaaagcagtt gatcagtatt gctcgaacga tcatcacaaa tccatcttta
     1981 ttgattttgg atgaagcaac aagtaatgta gacacggtaa cagaagcaag gatccaaaaa
     2041 gcaatggatg aagcaatcaa aggaagaacc agctttgtga ttgctcaccg gctgaaaaca
     2101 atcttgaatg cagatagaat cgttgtcttg cgtgatgggg aagtcattga agaaggcagt
     2161 catcatgagt tattagcaga aaatggattt tatgcggaac tttatcataa tcaatttgta
     2221 tttgaaagtt aaattaaaag aacctcgtta taacggggtt ctttttatat attttatgtt
     2281 gtttgttttt ataaggggca gaa
//
LOCUS       DAFBSV010000153         2001 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.160, whole genome shotgun sequence.
ACCESSION   DAFBSV010000153 DAFBSV010000000
VERSION     DAFBSV010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.160"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..376
                     /locus_tag="LLB18_002737"
     CDS             <1..376
                     /locus_tag="LLB18_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBK5245689.1"
                     /translation="NVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFRR
                     FPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTDD
                     WQKVMAAEVIATYLDGDLVYKK"
     gene            424..1824
                     /gene="yfcC"
                     /locus_tag="LLB18_002738"
     CDS             424..1824
                     /gene="yfcC"
                     /locus_tag="LLB18_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBK5245690.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            1857..>2001
                     /locus_tag="LLB18_002739"
     CDS             1857..>2001
                     /locus_tag="LLB18_002739"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245691.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAF"
BASE COUNT          553 a          339 c          432 g          677 t
ORIGIN      
        1 aaatgtttcc acagaggact tctttaatta ttgtcgatta gaggaaagtg gtgtaacagt
       61 cactagcggt acagatttac cgctgtttat tactgatatt cctgaatcga ttataagagc
      121 agtattccgt cgttttcctg aaggagaaga agtctgggag aaagaaacaa gcttcacgac
      181 aaccgagctg ctgaaaagtt ttacaagcaa cagcttcaaa gtaaatggtt tatcggagta
      241 cggagaaata aaagtaggga aaagcgccag cttagctgtt ttcagcgagg acctctgtac
      301 tgatgactgg caaaaagtga tggctgcgga agttatcgct acctatcttg atggtgactt
      361 agtttacaag aaataatgct tttcgatata acgttataaa acgaattaaa gagaggttaa
      421 aaaatggaaa caatgaaaag aaaattcacc ttcccacata gttatacatt gatttttatc
      481 ttaattattt tggctgcaat tttaacttgg ataattccta gtggtcagtt tgagacagtt
      541 gttgaaaacg tcgcaggtat ggaaaaaaca acggttgttc cgggaaccta tcaccaaatc
      601 gataaggcag attatggaca aggtttttcc tctatactaa tggcaccagc tgaagggatt
      661 atttcagctg ttgaggttgt tgcttttgtt ctcatcgttg gtggtgcctt cgggattatc
      721 ctaaaaacgg gagccatcga tcgagggctg tttaccttag caaaagttct gggagacaag
      781 gggatcttag ttattccgat gtcgatgatt ctattcagct taggaggatc aacctttggc
      841 atgagcgagg aagtcattcc cttatttgcg gtgtttattt ctctgatgtt ttctcttggc
      901 tatgattcca tgactgcgat cttgattcta tttttaagta cacaagcggg atatgttggg
      961 tcgacgatta atcccttcaa cgttttaatc gcacagggag tagctggcgt ttacggaaat
     1021 cccctgcttt ggtttcggat gctatcctgg attgtcatta ctgggatttc aattgttttc
     1081 accatgcttt atgctagcag agtcaaaaag aatccactgt cctctattgt ttatgagagt
     1141 gatttaaagg ttaagcataa gtttcaaaat tttgacactg aaaaagagtt ttcaacacaa
     1201 gataaactaa ttatcgccgg ttttatcgta ggtttaggaa tcatgatttg gggtatcatt
     1261 tccaagggat ggtatatggt tgaaatttct gcactattct taggattagg tctttttgct
     1321 gggggcatcg ctagattttc tcaaaaggaa attgctgaag cttttgtcga aggctgttca
     1381 gatttcgcct atgctgctgt aatcattggg ctagctagag gagtcttggt aatcttggaa
     1441 ggtggaatga ttattgacac tattctaaac agcttggcta accttttagg tggtcttcca
     1501 aaattcctgt tcactacgat tctactcatt tctcaagtaa ttgtttcctt ttttgttcca
     1561 tcctcctcag gagctgcggc attaacgatg ccggttatgg caccattggg tgatctaatg
     1621 aatgtaagtc gtgatgttgt tgttctaagt aaccagtttg gaaatggttt aatgaatatt
     1681 atctccccaa ctagtggtgt attactggca ggattagcca tcgcagagat taatttctct
     1741 aaatggttta aggttggctt caaaatattt gccatcttaa cccttgtttc tgctgttttg
     1801 ttatacattg ctacactctt ttagtcttaa tcatccatta ataggaggca atagttatga
     1861 ttaaaataaa tcaattagca ggaatgaata tccactattt attttattct ctcaaagaat
     1921 ttttcgctta tcaacagaaa attggtattt cttctgttga actttgggga ggtgctccgc
     1981 attttttcat agatgctttt a
//
LOCUS       DAFBSV010000154         1888 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.161, whole genome shotgun sequence.
ACCESSION   DAFBSV010000154 DAFBSV010000000
VERSION     DAFBSV010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.161"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            715..1800
                     /gene="xerS"
                     /locus_tag="LLB18_002740"
     CDS             715..1800
                     /gene="xerS"
                     /locus_tag="LLB18_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HBK5245692.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
BASE COUNT          703 a          317 c          257 g          611 t
ORIGIN      
        1 aaaaccacta gcccgccagc tagtggtttt tggtgtatca tgaattacct tttcgttaaa
       61 acaattatac catatttcct aaaaaataca attaatagac gaattatcat taccactttg
      121 atgaaaaaag ctgacataaa tttttctttt atttttataa tgaataaaca tttatcaata
      181 agcttttgaa aggcaggatc gtactttgtt gatgattgag atattgctac atcaatctca
      241 gcagttaaga tttttttgaa ttgttgcttg aattttttct ttatctaaaa aaattgtatc
      301 tccaggatgc aacccatttt ctttaagaaa ttccttttaa attgttaata ctactgagtg
      361 ccccacttct ctgaattttc tttaacttct ccctcccctt ttttatttgt atatacattc
      421 atatacgctt gttaatatca aatcaaccgt agtctctctt atgtctaatt atatagaaag
      481 attgttcttt ctatataatt tagacaattt aaaaaattaa gattgcctcc ttctgtttcc
      541 tttcctattc atgtatacca tttattttaa attattaaat ctatacctat ttatctgctt
      601 ttttgaaata aattaataaa tttcagagta taccaattga caaaacactc tataattggt
      661 atagtccaat tatagagata ctcctctccc ctacttatcg aaaggatgaa taacatgaaa
      721 aatacagaaa tatatcaaaa aatagataca atcatacttc atatgcccga ttatataaaa
      781 gattttgttc aagatcgtga ggataaagat caatcacctc gaactacttt agaatatcta
      841 aaaaattata agctctttta tgaatggctt ctgagtgagt ctatcgttcc cgatacttca
      901 atcacctcga taagacagtt aactgcctat gatctaaact tgtacaaatc tcatttgaaa
      961 cgtcgcacaa aggaaaatgt aaaaaaagag acaacaaaaa ctaagctcaa agataataat
     1021 aacttaggtc tatctacttc tactatcaat agaaatatca cagcattaaa ggttctattt
     1081 aaatatcttt cgaaaagttc caataatcct ttaggaaaac catacttaga aaataatcct
     1141 atggatcaag tagcaactat cacagataaa actacgttag ctgcccgtgc aaacgcaatc
     1201 gagaaaaaat tatttctaga cgaagataca caaaattatc tagattatat tgccaatgaa
     1261 tataaaaaaa ctttgagcaa acgagctttg atctattatc aacgagatgt agaaagagac
     1321 ctggcgatca atgcattgat tttaggatct ggattaagac tctccgaggt tgtaaatatt
     1381 aatttagagg acctatcttt agaaaagaat aatgtggtag taactagaaa aggaaataag
     1441 agagacgcag taaatatagc agcatttgca atggaatatt tagctaatta tctagctatt
     1501 cggaaagaac gatacaaagt aacagaaaac gaaaaagctt tatttctagc aatttatcaa
     1561 ggagaagcca agcgtatatc cggtattgca atcgaacgga tggtagcaaa atattcaaaa
     1621 ggattcagag tccaagtcag tccacataaa ttacgtcata ctttggctac tagactctat
     1681 caacagacaa attcattggt attaactgcc caacaattgg gacatacaag tacaaataca
     1741 acaactttat atactcatat agacaatgca gctacaattg atgctttgaa cgctttgtaa
     1801 atgtagtaaa aaatagtata ataatgaagc ctgtctctaa aattagataa aagcccaact
     1861 ttaaaggcaa gcttcattat cattttta
//
LOCUS       DAFBSV010000155         1870 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.162, whole genome shotgun sequence.
ACCESSION   DAFBSV010000155 DAFBSV010000000
VERSION     DAFBSV010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1870
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.162"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            24..1868
                     /locus_tag="LLB18_002741"
     CDS             24..1868
                     /locus_tag="LLB18_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245693.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT          613 a          342 c          311 g          604 t
ORIGIN      
        1 aagttttaga aaggaatacc tttatgtctt tttttaataa catatataat aaaaaagaat
       61 ctttttattt acgtataaag tggagcataa tcattatatt atcattgtta tttttaacag
      121 gaattgctta tttcttttat tttatttttt ctcctgcgga cagcaatcaa atgaaagaaa
      181 taaaagattc gtgggttttc tatacaaaag atgatcctga ttttaagttt gacagcaagt
      241 acactcgtac gattcctacc gtggataaag acgaaacatt cattatggaa acgacacttg
      301 aaaaaccgtt ggacgaagca aatttactaa tcaaaggaaa ccatcaatgg attactgtat
      361 atctaggcga aaagatttta taccaacgga aagattatca ggaagaaagc aatcccggac
      421 tctcattggc tgtgatagat ttaccagcaa attatatcgg aaaaaaattg acccttacag
      481 tctcatctcc ttatcagaac tatgctggac tgccaccgaa agtttatcta ggaacaactg
      541 gaccattgat tagttttatt tattcacaat cagtgccgca agtattgacg atgataatcg
      601 ctgtttttat cgctataggg acctttttct atacgatcta cttgatgtat aaacaaaaac
      661 gtcttgaata ctcacttatt ctcttaagtt gctttgcttt ggcattagga tttgaagctg
      721 tatcagaaga tattttaagt ggtattcttt ttgaaccatt cgttcattct tttttatctc
      781 atttatttat tatcttaacg tcagctttca tcatctgcta ctattggagc cgaatgtttt
      841 actataaaaa atggtacgga attttttgta cgttccaact tttgattttt atcggcgttc
      901 tgctttatgc aacttttact cctgcagaac ttcctgaatt aatgccgatt gctaatattg
      961 ctagtgttat aagcacttta gtcacttcac ttgcatgcat tggcgaagca tataagaata
     1021 accgttttta tgtagcttgt acaccttgga tcgtcttggt agccattatc cattgcttga
     1081 tttacatcca aacggcatta ggtatctatc aaacaacgat caattggtct acgattttat
     1141 atattatcat tctaatcgtt attatcagct acaatctaat cgatcacatc ttaaataccg
     1201 acaaagatcg gagacaagta gatttcttaa aaatcaaaaa tgatttgttg gagcaacatt
     1261 atgagcagct tcgacagcat atccaagaag taaatacact tcgcctggaa tttgtccaag
     1321 agatggagaa tctgcaagat ttaatgcata cggaccaaac aaaagctaaa aactatgtgg
     1381 aaaagatatt agaagaagca aaaaatttcg aaatgctgtg ttctttttgc aaccaccagg
     1441 tgacaaatct tatcttagcg cgttaccaga agttagctgc caaacggaat attcagataa
     1501 ccttccaagc agatcttccc gaagaacttc ctatcaacga tgacgatctg gctcaacttt
     1561 tgatccacgc tttagagcat tcctttagag aaactcatgc catcgaaaat ccactgtatc
     1621 gaaaaattta tttgtcgata cacgaacaag aggaacattt cgtcatttgt tgcgaacata
     1681 gtgcacatta cgatacaaac ctatttagtc gaggcatcac agaagaatta gatgatcagg
     1741 aacgttttga cttaatgatg atgaaagacg tagcggatcg ttacacagga acactaacgc
     1801 aggaaaaaga tactttcatt gatcggatca ctgttcaact ctctcgaaat tacccgaatc
     1861 ctgtataaaa
//
LOCUS       DAFBSV010000156         1792 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.163, whole genome shotgun sequence.
ACCESSION   DAFBSV010000156 DAFBSV010000000
VERSION     DAFBSV010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1792
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.163"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(232..609)
                     /locus_tag="LLB18_002742"
     CDS             complement(232..609)
                     /locus_tag="LLB18_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245694.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(909..1790)
                     /gene="galU"
                     /locus_tag="LLB18_002743"
     CDS             complement(909..1790)
                     /gene="galU"
                     /locus_tag="LLB18_002743"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBK5245695.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT          523 a          388 c          259 g          622 t
ORIGIN      
        1 aagtaatctc ttatccaagt gcaagcaaga aaatacaaaa aaacattggt atgatttata
       61 tatatataaa taacataaaa aaaggaatgg cttatcccga tacaacaagc attcctttaa
      121 aaaagattct tttatataag tgaaaaaagc ttttttccac caattaaata aatctctcat
      181 ctcaatagtt tatccattat tttatctttt tttgcgtata cctactaaat attaccgtct
      241 tcttctcgtt cttctacttt gttcgagaga atctgtacta gaaaaagtag ttgtatgtct
      301 accttttctg cctatccgag actttctttt catatatggg atataaatga ttagatacag
      361 tacagcaaaa aataaagcaa atacgcaagc ttcccaacta cctaacgcca attcaaccat
      421 caaggtagca accccaacgg atgctgcata ccagataaaa atcagaaacg tttctttttt
      481 tctgaccatg cgaaacatga taaatagact aataagcaat agtggcaaca caaatatcca
      541 attgcttcct tccatcagcc acttgagtat atcaagcagc gactgtgcaa cagcgactaa
      601 ttttcccata gtgaacacac accttttttt ataattaaaa aattcgcctt tttattctac
      661 tatgaatctt ctggcttggc tttcatttct cttatgtaat cattttcttt tatacaactt
      721 aaaaaaaaat taaaccatta gcataatatt ttctgaatct attcacgaaa gtctttttct
      781 atctttcgtt ttccacgact caactgatct agagtcaaaa aactaaaacg acagttgcgc
      841 aaatgacgca caagctgccg ctttaataac aaatagcctt tcattctcag caggccactt
      901 atttccagtt aactttctgt tcttagcttt ttactcaact ggataatata tgcacttaat
      961 gaagtcccaa tttccgaatg ttgaagtcca tattcaatat ttgtcttcat atatcctaac
     1021 ttatcgccta cgtcgtatct ttttccttta aactctctcg catagaccgc ctctgtctgg
     1081 ttaagagtct gaagtgcatc cgttagctgt atctcgtttc ctgctcctgg ttcttgagtt
     1141 tctaatatct caaatatttt aggagtcagt agataacgtc cgataatggc taaattactt
     1201 ggtgcttttc ccatttcagg tttttctaca aaccctttta ctctgcaacg acccttttcg
     1261 ctatctgttt taggatcaat aattccgtat ttagatgttt cattttctgg tacacgcatg
     1321 acggcaacag cggaagcttg tgtttcttca taatccatca tcaattgttg agtcaatggg
     1381 atatcatctt tcatcaaatc atcccccagc atgacgacaa acggttcatt tcctataaat
     1441 gcttttgctt gaagcacggc atcccccagt cctcttggat gagattgacg gatgaagtga
     1501 agattgactt gagtcgtttc ttcaactaaa gcgagtaatt ctgttttttc cttttcccgc
     1561 aaattgtttt ccaattcgat atttgcatca aagtgatctt caatgggtct tttttctttt
     1621 cccgttacga tcaagatgtc ttcgattccc gaatccaatg cttcttccac aataaactgg
     1681 atcgttggtt tatccacgat tggaagcatt tcttttgcca tggcttttgt tgccggcaaa
     1741 aaacgtgttc ctagcccagc ggcaggaatg actgcttttt tgaccttcac tt
//
LOCUS       DAFBSV010000157         1718 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.165, whole genome shotgun sequence.
ACCESSION   DAFBSV010000157 DAFBSV010000000
VERSION     DAFBSV010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1718
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.165"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(606..962)
                     /locus_tag="LLB18_002744"
     CDS             complement(606..962)
                     /locus_tag="LLB18_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HBK5245696.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            complement(976..1386)
                     /gene="spx"
                     /locus_tag="LLB18_002745"
     CDS             complement(976..1386)
                     /gene="spx"
                     /locus_tag="LLB18_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBK5245697.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
BASE COUNT          529 a          315 c          242 g          632 t
ORIGIN      
        1 tgtttgttgt cttgaattga atcaagacgc cctacacatt tggtttgtct tactttgttc
       61 agttttcaaa ggtctacttc atcaggagtg ttccccgatt cgtttttggc tgccgtagca
      121 acttttatat catatcagag agacaagtaa ttgtcaactc ttttttaaaa gtttttttga
      181 tttcgttttt cgaaatctta cagcaactca tttatcataa cttatcattt gttatttgtc
      241 aaggactttt ttgaagtttt tttcgataga atcaagcttc acaagtggtt cttttttaac
      301 aactcagtta tcttatcatg tcatttctaa catgtcaaca actattttat atgtttttta
      361 aaatactatt ttattgcttt gctacttaaa acaacagaaa tgaatatatc atgtaaattt
      421 acacatgtca atatattttt aactctatat ccccacctag atttgaattt tgaccacata
      481 aattgagcat gtctctatag tagaaaaata aagtcaaaaa aagaacacat aacacgcttg
      541 atgctaagtg ttcgactgtt acaactgtat gaaatgctca gtgacttgat taaaacagtt
      601 aaagtctatt tatttaagat aagctgttcc atcaactgct cattgtatcc aataaataga
      661 acttcatcga taataatcaa aggacgtctg aggagattgg tatgttgtgt gcataaaaaa
      721 atcagttgtt tttttcctac acaggaaagg tcaatcgcaa tgttgtgaaa agcctcagac
      781 caagtcgcaa atagctgttc tgcttgcact tcttcaaaac tgcataattc ttctgcttct
      841 tctgtactta gatcgcgttc ttctaagtca acaaattgat aaggcaattg atggtgttct
      901 aaccattgtt tcgccttcag acttgttaca cagtgcgctg atccatagac tttcacttcc
      961 acgaaggctc cctccctatg aatttaagat gttattgttt tgtaaataga tcagatttct
     1021 ggcaacacat cgaatttcac gagggacaaa tgaccggatc tcatcttcat taaatccgat
     1081 tagtattctt ttttcatcaa tcaaaatagg tcgtctcaat aatgaaggat attctttgaa
     1141 taagacgatc atttgcttta aagttaattc gttaaaatct atgcccagct tttcgtaaat
     1201 tttcgaccga gtggaaataa tatcttgaac tcctccttca gtcgctgcca agatcttttt
     1261 gatctcactt tctgttaacg gttcggcaaa aatattcttc tcttcaaatt caagttgatt
     1321 cgcttgcaac catgctcttg cttttctaca ggaagtacag ctaggcgaag tatatacttt
     1381 tatcattttc tcactccttt ttaattataa tccaattcta cagtaatttc ttttaaaata
     1441 ccaattatta gctaataaaa tataaaaaaa atcaaaataa ctgattattt acgtttgaat
     1501 aatgagaatt tttctatata ttctctattt tgataatagt attctcattt tcaaaataaa
     1561 taagggaggt gtgacaaaat tcttgtcaca cctccctttt ccgaataaac tgtgttccag
     1621 aaatagcttc ttcgaaaata agctgaaatt tcacaaaaat ttgagaagca attttcgtac
     1681 attccttctt ctttcttgaa actgaccact tctgtcac
//
LOCUS       DAFBSV010000158         1676 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.166, whole genome shotgun sequence.
ACCESSION   DAFBSV010000158 DAFBSV010000000
VERSION     DAFBSV010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1676
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.166"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(365..1657)
                     /locus_tag="LLB18_002746"
     CDS             complement(365..1657)
                     /locus_tag="LLB18_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBK5245698.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
BASE COUNT          516 a          342 c          284 g          534 t
ORIGIN      
        1 tatgggctac tctgtgatac ttattagcca ttaaactatt ttacccacat agcatatatt
       61 ttgaaatcgt tcattccgta aattcaacta aatatgccta aaaaaataaa aaatctaaga
      121 tagaataaga tttattcagt cttagatgga tttatagcaa ctttttcgta acaactttaa
      181 aaaatacgaa aagaaagagc tgttttactc tgactacgtt gctaaattgt cgtttaatca
      241 ttcatttaaa ccaaatcttt ttttatagaa ttcgttttaa tcctcctgaa tccaaaaact
      301 atgaaaaccg taattaaata gttaagagtt tttaaccacc ataattctct cggctatttt
      361 gaaatcagat aaattttgat cggacacata gttgaataaa cctaccgttg ttacggaagg
      421 taaatcgcat acttttcatt ctagaggaga aggtctcgtt gatcattaac tgattaagca
      481 ccatagccca gttttgaatt cgaccacctg accacttcgc gtgtaattct ttcgtgcgta
      541 aataaagtag ttttaggagt gcattctcat tagagaacgc tccttttttt gtgacttttc
      601 tgaagctgga gtggacactt tcaaccgcat tggtagtgta cataattttt cgaatggcac
      661 taccataatc aaatagttgt tcaacatgtg caaagttccg tttccagaca tctacagcac
      721 cagaataatg agaccaccga ttttgaaaac tgtcaaaagc agcatgtgca gcgtttagag
      781 aagaagcacc gtagaacttt ttcatatctc ggcagacttc cttatagtcc ttacttggaa
      841 tatagcgcaa tgcatttcga acaagatgaa caatacagcg ctgaacaatt accgatggaa
      901 agatcgcttt tgcgccttct tcgaggccag aaacaccgtc catcgaaatg aaaaagacat
      961 cttcgacacc acgtgctttc agttcatcaa atacttgcat ccagcgattt ttagattctg
     1021 tttgatttaa ccataatcct aaaatctcct tatttccttt gagatcatag ccaagaatgg
     1081 tgtatacagc atattctttg gcttcataat tttctcgtaa agtaacatac atacaatcaa
     1141 cgaatagaaa ggcataacac tttgctaggg ggcgggcttg ccattcttcc aattcaggaa
     1201 ggacagcgtc agtgatatct gaaatcattt catgggaaat atcaaagcca taaatagctt
     1261 cgacggttgc ggcaatatct cgttgactca ttcctcgtgc atacatggaa agaaccttcc
     1321 cttcgatgtc ggagacatct cgttttctct taggaattaa ctctggttca aaggaagctt
     1381 cccggtctct aggaacatca atagctactt caccaaaact ggttttaagc gttttagttc
     1441 catagccatt tcgacggtta tcgtgttcct taggctcttt agaatgggca tcataaccta
     1501 aatgattatt caattctcct tgaagcattt tttcaaaaag gggcccaaac acatctttca
     1561 aagcatcttg catgtcatcg acagattcag gttgataggc attcagaatg gattcagcta
     1621 acttttcggc atcaggattt cttttctttc tagccatcgt gtaatcacct cttgat
//
LOCUS       DAFBSV010000159         1656 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.167, whole genome shotgun sequence.
ACCESSION   DAFBSV010000159 DAFBSV010000000
VERSION     DAFBSV010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.167"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            50..1438
                     /locus_tag="LLB18_002747"
     CDS             50..1438
                     /locus_tag="LLB18_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HBK5245699.1"
                     /translation="MYKERDDLNYTLIINKDGNYSWRPLVLLHPILYVDLVNCLTKED
                     HWEELKKRFSEFKKDKNINCYSIPVEASKGSKRTDLGETILNWWEYFEQKSLAQNIKY
                     QYCMFTDIADCYPSIYTHSITWAMYGKEKVKNDENKCSGSLGDKIDKKISGMQHNQTN
                     GIPQGSVLMDFVAEIVLGYVDLRLSKELKKLENLKDYKVLRYRDDYRIFSNNRNDLEQ
                     IMKVLSEVLYDLNFKLNSSKTKLSDDIIIDSIKKDKLYWEEIKASIRMNATNLDGDRE
                     IRYSINLQKHLLEIKKLADKHPNSGQLKKALSEFNKERIIKITSKPNDLLPLIGILVD
                     IMINNPGSLPQCVLIIGQLLNFENESKAREIVEMIINKYALKPNTEFMMIWFQRLTTI
                     FGEMFDSVLSSEFVSKIKDPVSNQMFSVDWLNEDAKKSFYEGTIKDEEKYIKMSKKIY
                     ITEFDDFNDYPF"
BASE COUNT          658 a          197 c          271 g          530 t
ORIGIN      
        1 ttcaaaaaaa aaccaaccga aagatataaa agatattgta gatacacgaa tgtataaaga
       61 acgtgatgac ttaaactata cgcttattat caataaagat ggaaactatt catggcgtcc
      121 tctcgttcta ctacatccta ttctatatgt agatttggtt aattgtctca ctaaagaaga
      181 ccattgggag gagttaaaaa agaggtttag tgaatttaaa aaagataaaa atattaactg
      241 ttattctata cctgttgaag cttccaaagg ttcaaaaagg acagatcttg gtgaaacaat
      301 actaaactgg tgggaatatt ttgaacaaaa aagcttagct cagaatatta aataccaata
      361 ttgcatgttt actgacatcg ctgattgtta tccatcaatt tatactcact ctataacatg
      421 ggccatgtat ggtaaagaaa aagttaaaaa tgatgaaaat aagtgttcgg gctcacttgg
      481 cgataaaata gataaaaaaa tatctggaat gcaacacaat caaacaaatg gtatccctca
      541 gggttccgtt cttatggatt ttgtagcaga gatcgttcta gggtatgttg atttgagatt
      601 atcgaaagaa ttaaaaaaat tagaaaattt aaaagattac aaagtactca gatatagaga
      661 tgattataga atattttcaa ataatcgtaa tgatttggaa caaattatga aagtgttatc
      721 agaagtctta tatgatttaa attttaagtt aaattctagt aaaacaaaat tatcagatga
      781 tattatcata gattctatca aaaaagataa gctctattgg gaagaaatta aggcaagtat
      841 aagaatgaat gccacaaact tagatggtga tagagaaatt cgttatagta taaatttaca
      901 aaaacattta ttggaaataa aaaagttagc agataagcat cctaattcag gccaattgaa
      961 aaaagcactt tctgagttta ataaagaacg cattattaaa atcacttcaa agccgaacga
     1021 tcttttacca cttattggta tcctggtaga tatcatgata aataacccgg gttctttgcc
     1081 gcagtgtgtc ttaattatag ggcagttatt aaatttcgaa aatgagagta aggctagaga
     1141 aatagttgaa atgattataa acaaatatgc tttaaagcca aatactgaat ttatgatgat
     1201 atggtttcaa agattgacca ccatttttgg agaaatgttt gatagtgttt tatcatccga
     1261 atttgtatct aaaatcaaag atcctgtctc taatcagatg ttttctgtag actggctaaa
     1321 tgaagatgct aagaaatctt tttatgaagg gaccattaaa gacgaagaga aatatattaa
     1381 aatgagtaag aaaatatata ttactgaatt tgatgatttt aatgattatc ctttttaagt
     1441 gaaaatttag aatgaatata aaaaacatta caatctaatt tttttaaaaa aatgttatat
     1501 cggaagtaat ctcttgattt ctatactata agataagaaa accactattt aacaaggtta
     1561 ttcgaacctt attttaagtt acttattatt taatgtatcg aaaaaggtga aataggtttg
     1621 ttataataag aattaagtaa gacatgaatt gtctaa
//
LOCUS       DAFBSV010000160         1583 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.168, whole genome shotgun sequence.
ACCESSION   DAFBSV010000160 DAFBSV010000000
VERSION     DAFBSV010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1583
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.168"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            292..1479
                     /locus_tag="LLB18_002748"
     CDS             292..1479
                     /locus_tag="LLB18_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBK5245700.1"
                     /translation="MYFLGIDIGKRTHVASIMNEEGKVLLKGFSFPNTTEGAESLIER
                     MVDYSGAPSDFVIGMEATGHYWLSIFSYLHESDYLIHVVNPLQTDGWRKGTEIRKRKN
                     DIIDSVLIADLMRYGSFVETVLSDENVFSLKQLSRYRTYLVGTASDFKRKIIAVLDQV
                     FPEYATIFTKQGVFGKASKELLLAFSAPIDLENISSETLAQYLAELSRNRIKAEKADQ
                     LKQAASNSFGVKFAQEAFTFQLRSMIEQLKFIESQIKETEREIKHIMDTLNSVILTIP
                     GIGPINGATILGEIGDIQKFSNPKKLVAYAGIDASVTQSGQYEATHNVMSKRGSPYLR
                     KALFSAALVASQCDPVFSAFYQKKVSEGKHHLTALGAVSRKLCYVIHAILTKNEPYII
                     VSD"
BASE COUNT          467 a          296 c          315 g          505 t
ORIGIN      
        1 ttttaacctt ccggttttga ttggataacc ctatgaacca tcgttatttt aatttggtat
       61 taactcattt cttttgagat aatatattta ttggattgag aggctaagcc gttcccccct
      121 tgggccattg aacccgcact cgagagactg gctcctctct ctgataagtg gattgcgtat
      181 gagttagatg ttgaaagtcc ttactttact ccgtatctcg tacaaggtag tgacgctttt
      241 cagttgagtg gatttcaatc caaaattctt tttttgaaag gtcagatata catgtacttt
      301 ttaggcattg atatcggtaa acgcactcac gttgcttcta tcatgaacga ggaaggaaag
      361 gtattactaa aaggtttttc atttcctaac accactgaag gagcagagtc attaattgag
      421 cgaatggtcg actattccgg agcacccagt gactttgtta tagggatgga agccacgggg
      481 cactattggc tgtccatctt ttcatacctt cacgaatcag attatttgat tcacgttgtg
      541 aatccccttc aaacagacgg atggcgtaaa ggtacagaaa tacggaaacg aaaaaacgat
      601 attattgatt ctgttttgat tgctgactta atgcgctatg gctcatttgt cgaaacggtc
      661 ttatccgatg aaaatgtttt ttctttgaaa caactttctc gttaccgaac ttatttagta
      721 ggtacagcga gcgacttcaa aagaaaaatt atagccgtat tggatcaagt ctttccagaa
      781 tacgcgacga tttttaccaa gcagggcgtt ttcggaaaag cttctaaaga gttattgctg
      841 gcgtttagtg ccccgatcga cttagaaaac atttcctcag aaactttggc ccaatactta
      901 gctgagttaa gcaggaaccg aatcaaggca gaaaaagcgg accaattgaa gcaagcagct
      961 tctaactcct ttggagtaaa atttgctcaa gaagcgttca ccttccaact acgttcaatg
     1021 attgaacaat taaaattcat tgaaagccaa ataaaggaaa cggaaagaga aatcaagcac
     1081 ataatggaca ctttaaattc tgttattctc acaattcctg gaattggtcc tataaacggt
     1141 gcgactattc ttggtgagat cggagatatt caaaaatttt ctaacccgaa aaaactcgtt
     1201 gcttacgctg ggatagacgc ttccgtgaca caatcagggc aatatgaggc aacgcataat
     1261 gttatgagta aacgagggtc tccatatttg cgaaaagcct tgttttcggc ggctttagta
     1321 gcttctcaat gtgatcctgt ttttagtgcg ttttaccaga aaaaagtttc cgaaggaaaa
     1381 catcatctaa ctgccttagg tgcggtttct cgtaagcttt gttacgtgat tcatgctatt
     1441 ttgactaaaa acgagcctta tataattgtt tctgattagc tattgaacat tcaaaaaaac
     1501 taatggtaag aagcttattt gttgtaccct tttttcggaa ttatctgtta taaaatattt
     1561 tttgatttgg ctaattttta ctt
//
LOCUS       DAFBSV010000161         1581 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.169, whole genome shotgun sequence.
ACCESSION   DAFBSV010000161 DAFBSV010000000
VERSION     DAFBSV010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1581
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.169"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            200..742
                     /locus_tag="LLB18_002749"
     CDS             200..742
                     /locus_tag="LLB18_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245701.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..1347
                     /locus_tag="LLB18_002750"
     CDS             898..1347
                     /locus_tag="LLB18_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBK5245702.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMPDGMATLFLTKIIRCCECCGVMAPIALDNEHPRI"
     gene            complement(1377..>1581)
                     /locus_tag="LLB18_002751"
     CDS             complement(1377..>1581)
                     /locus_tag="LLB18_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HBK5245703.1"
                     /translation="KVEFVHQYQFETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQI
                     RQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          600 a          217 c          308 g          456 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tcttgatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccagatgg aatggcaaca
     1261 ctttttttga caaaaattat aaggtgttgt gaatgctgcg gtgttatggc tccgattgcc
     1321 cttgacaatg agcatcctcg gatctgattt tctccggcag aagcacaatc attcaattac
     1381 gctgcctctc cagaggtatc agatccgcgc tcattatcaa ggattcgctt cgccaatctc
     1441 tgttgtcgaa tttggatcgg tgtttcatac gccaacgtgc catgtaagcg tagatagttc
     1501 caccaatgca cataatcaaa caattctaga cgtagctgtg ccagtgtctc aaattggtat
     1561 tgatgcacga attctacttt g
//
LOCUS       DAFBSV010000162         1577 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.170, whole genome shotgun sequence.
ACCESSION   DAFBSV010000162 DAFBSV010000000
VERSION     DAFBSV010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1577
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.170"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            535..1554
                     /locus_tag="LLB18_002752"
     CDS             535..1554
                     /locus_tag="LLB18_002752"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBK5245704.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT          541 a          257 c          332 g          447 t
ORIGIN      
        1 attttttgca ttatctacag ttcaacttat aatctgttta atgggacatg tgggtgccaa
       61 ccattttttg ttatgcaata gtactattta gttgttgcat ggatccgtag taaaagtcca
      121 agtacaacga gttgcgccag tttacatagc gttttgtatc cagaatgttg actaaaacaa
      181 aagttcctat gtcaaccgtc aacagagaca atctgtccgt tgcaggacct gacagattta
      241 gaaatgttca atctgtctct tatgtatttt aaatcaatac tcactaggag aagtttccta
      301 acctcctaat agtaatgctg gtagtaacat tgtcaaaact gcttcctctt aggaacaagc
      361 aaagcataac gagtgtaaaa ataaaatgta gactattgta acatatcatt gattatttca
      421 agtaaaaacg ataaaagaag taaacaaaca cttaaaaaca atggaaatta gtcccaactt
      481 taagaaatgt atactataat ggaaattatc aattatttat ttggaggaat atccatgaaa
      541 caaaaaatcg cagttcttgg tcctggatct tggggcactg ctttagcaca aacattggca
      601 gaaaacgggc atgatgtccg tatttgggga aatgtacctg aacagattga tgaaatcaat
      661 aagtatcata caaatcagca ttttttacct gatttgacga tcccagaatc gattatcgga
      721 tataaagaat tggcagaagc agtggataac gcagatgcta ttttatttgt tgttccaaca
      781 aaagcgattc gttcagtcgc acaggaactt attggtaaaa tgaatactaa gccaatcatt
      841 atacatgcaa gtaaaggact agaacaagat acgcataaac gaatctcaga agttttggct
      901 gaagaaattc cagaagaaaa aagacaggca attgttgtat tatctggtcc tagccatgct
      961 gaggaagtgg cagtacatga tatcacaaca attacagctg caagtattga tcaaaaagca
     1021 gcagcctatg tacaaaaact gttcatgaat gattatttca ggatttatac aaataatgat
     1081 gtgattggcg tagaaactgg tgcagcactg aaaaatatca ttgcaattgg tgccggcgct
     1141 atccatggat taggattcgg agatgatgca aaagcagcaa tcatgactcg aggattggca
     1201 gaaatcagcc gtcttggtgt cgcgatgggt gccaatcctc tgacatttat cggtttgagt
     1261 ggtgtggggg acttgatcgt tacttgtaca agtgttcatt ctcgcaattg gcgtgccggt
     1321 aacttgttag gacagggaca taagctggaa gaagttctag aaaacatggg aatggtcgtt
     1381 gagggtgtgg caacgacaaa agcagcagta gagctagctc aacagctagg tgttgagatg
     1441 ccaattactc aaacaatcta taatgttttg tataatggag aagatatcaa aaaagcagca
     1501 aaagaaatca tgttacgtga cggaaaaatg gagaatgaat tttctcttcg ttaaatagat
     1561 gatcaatagt taatcgt
//
LOCUS       DAFBSV010000163         1545 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.172, whole genome shotgun sequence.
ACCESSION   DAFBSV010000163 DAFBSV010000000
VERSION     DAFBSV010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1545
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.172"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(188..1207)
                     /locus_tag="LLB18_002753"
     CDS             complement(188..1207)
                     /locus_tag="LLB18_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HBK5245705.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RSDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            complement(1218..1424)
                     /locus_tag="LLB18_002754"
     CDS             complement(1218..1424)
                     /locus_tag="LLB18_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBK5245706.1"
                     /translation="MNNRTFDILKWIAIVVIPALATFVGLVGKGVNWRYTDITVMIIT
                     GFGAFLGSILGVSNRTYKKISSDK"
BASE COUNT          432 a          321 c          265 g          527 t
ORIGIN      
        1 ggttgttgcc acataaagcc ataaacaatc aaccagtaga atgtgtggca acaaacctgt
       61 tatcgcatag cttggagtgt gactattatg ggtgatagtg aagatatgcg ataacatcac
      121 tattttatcg aatgattttt atagttgtca atatagttat gtaatgctcc tcaacgagga
      181 gctattttta tcgtttagga atatttaaat accaacgttt gtcatggaaa tcttgcgcac
      241 cgcctttagt gtttccctct ggatcattcg ttgcccgcat catgacatag actttcttat
      301 tagggaagtt acgcatgtta aaagatacat gatagccaac atttccagaa gtattataag
      361 cttgatttac atctgatcta taaattccat cagctcttac tcgagctaat tctttcccag
      421 tattgtaatc cataatgaag atatactcgt atttatagtt agcaatgtgc catccagcta
      481 catgcaaatt tgcattttcg atttctccaa actgatcaat gtgggcgtaa ttcgttccat
      541 ctgtcagtgt aggattagct gcaccagctc gtgttggatc aatgacaggc ttgttttcag
      601 aagttgttgg attttcatcg gtaaatccat gagctaaatc atatgctaat ttttctttac
      661 ttacgcccat ttcagaaaga taaccgtaag gatctgtatg atcgccccag atgttttgtg
      721 ttacccataa atgcgatttg attcccggtt ggttataagg agtgtccaac gttaatggaa
      781 taccatattt cattgctgaa tctctagcca attcaacgta tgccttgtag tttttctcaa
      841 acgttgcttt atcatgtgtg tgttgtaact caatctgcac aggactgttg gcattagcat
      901 acgaaccagc accgtactgt acataaccag gttgaccgac ttgataaaca attccgccgt
      961 ctcccacaat ataagcagta taagcgctag tccatgaacg ttgcatatac tgcgcttcat
     1021 tgcgtcctgt tgctgtttca ttagccgttt catgcagtaa aatatactga ttatttgcta
     1081 cttgtgagct accttcattt gcgcccaaat taaattcatt gttgatagta taggcaaatc
     1141 cgttaattgg caataaaaaa agagccgtta acaggctcat cgcagtaata gtaattttct
     1201 ttttcatatc tatcctccta tttatctgat gaaattttct tatacgttcg atttgataca
     1261 cctaaaatac tccctagaaa tgctccaaaa cctgtaataa tcatcaccgt tatatctgtg
     1321 taccgccagt taacaccttt tccgacaaga ccgacaaaag tcgctaaagc ggggataact
     1381 actatagcga tccatttcaa aatatcaaag gttctattgt tcatactatc cacctccctt
     1441 cattggttgg gctactttct ttttcaatcg cttgttttct tctatcaata tttctctttc
     1501 tgaaagcaag gcatcaattt gcccgtccag ttgttcaatt ttatc
//
LOCUS       DAFBSV010000164         1457 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.173, whole genome shotgun sequence.
ACCESSION   DAFBSV010000164 DAFBSV010000000
VERSION     DAFBSV010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.173"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            109..1041
                     /locus_tag="LLB18_002755"
     CDS             109..1041
                     /locus_tag="LLB18_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HBK5245707.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            1113..>1457
                     /locus_tag="LLB18_002756"
     CDS             1113..>1457
                     /locus_tag="LLB18_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245708.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQD"
BASE COUNT          640 a          169 c          228 g          420 t
ORIGIN      
        1 gatgaaataa atcaaaagta tgatgaaaca ttaaaaaatg tctattcttc acttatcgtt
       61 tcaaatatag aagaaacttc atcttctgaa ataaaaaata agctttcttt gttaaaatta
      121 aaagaaaagg aatatattat tgacgatgct gtttctgtcc ctcttatttt aaataaacga
      181 gagaaaaata atttaaagaa aaaaatgctc attccatttg attcagaagt gaaaggatta
      241 ctcaataaac taactatttc taatatagac tcgactaggg aaaaaatcat aaaaatattt
      301 gataaaatta ataatttatt caagaatgac aatgctgaat taaggaaggg tcttttagag
      361 tttaaacttc aagaactaga acttcattac tcttatttag tgaaaattac cgaagaaaaa
      421 gaacaacaaa aagcaataaa agaacagatg atagaagagg aaaaagttcg tagagaaatt
      481 gatcgtgaaa agaaacgtat tgataaagaa caacgtcaat tcaattctga aatttccaaa
      541 ttaatcgcat atatgcaaaa agctaatgca gatgtggaaa aagaattata tgcaaataaa
      601 attcaagaac tggaagaaaa attaaaagaa ttagaagtta tacgtgaaaa tgtattacaa
      661 agagaattaa atactagagc cggttatgtg tatgtaatta gtaatattgg gtcttttggt
      721 gaagacatat ataaaattgg tatgactaga agattagaac ctatggatag aataaaagaa
      781 ttgagtagtg catcggttcc atttgaattt gacgttcatg cgatgatttt ttcagaggac
      841 gctccgtctt tggaaactaa attgcataat cattttagaa aacaagaagt taataaaatt
      901 aatcaaagaa aagaattttt caaagtttca ctagacgaaa tagagaaagt tgttttagaa
      961 aattataatg gaacagtaac atttacaaaa ttagctaaag ctgaacaata tagacgatct
     1021 ttagaattgt caaaagatta aatatataaa aagccttcgg gctttttctt ttaacaatta
     1081 ataggaacgt atattcgaaa ggaatagaaa taatgtggtt agaaaaaata aatgacaaaa
     1141 aatttaagta caccgaacgt tatacggatc ccttaactga aaaaaagaga aaagtgtccg
     1201 ttactttatc tagcaattca cgccaagctt ggaatcaagc taacttactt ttgaatgaaa
     1261 aaatcgcaga aaaaataaaa cgaaatgaag aattaccact aacttttgga gaattaaaaa
     1321 ctaaatggga tgaaaaatac aagccaactg taaaagaaag ttcctatcga acaactcagg
     1381 tttatctatc attaatttca aaatatataa aagatgatgt acttgtaaaa aacgttaata
     1441 gtaatcttat acaagat
//
LOCUS       DAFBSV010000165         1427 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.174, whole genome shotgun sequence.
ACCESSION   DAFBSV010000165 DAFBSV010000000
VERSION     DAFBSV010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1427
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.174"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            94..1389
                     /locus_tag="LLB18_002757"
     CDS             94..1389
                     /locus_tag="LLB18_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBK5245709.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT          450 a          283 c          267 g          427 t
ORIGIN      
        1 tcaccaacat cttttttgta taaaaaaata tagaaaagac accctgaaat cctttagaat
       61 taatttggct accaattcat aggaggattc aagatgtctc atactcagct tatcaaagat
      121 accctaaata ttctagacct aaatatctat ttcgaggaaa attgtttaac taaagaaaaa
      181 tacaaagggc aaatttgctt gatttacaaa ggaactcttc tgtacaagcc agaagagtgt
      241 tcccattgtc tttgtgtcgt cccctctagg atcattcgtt gggggacgac aaccgttcgg
      301 ttgttactga atgatgtgtc tgagtatcgc acttatctgg agctgaagaa acaacgattt
      361 aaatgtaagt cttgccaaag aacattcgta gcggatacct ctgttgctga aaaacactgt
      421 ttcattagtc aaaaagttcg ttggtctgtc attgctcgct taaaagagaa tacttccatg
      481 acggaaatcg ctcgtcagaa aaatatttcc acttcttcgg tctatcgtgt catgaagcga
      541 ttctaccgcc cattgaatcc tttcaaacag actttgccaa aggtcttatg ctttgatgaa
      601 ttcaaatcgg ttcgaagtgt tgccagtgca atgagtttta tcatgatgga cggacaaagc
      661 catgcattat tggatattgt cgaaaatcga cgcttgcctt atttagaacg ctatttttct
      721 cggttttcat tagcgactcg tgaagccgtt caattgattg ttattgatat gtatgcgcct
      781 tatgtttcgt tggtgaaaaa gcttttcccg aatgctcagt tgatcatcga tcgtttccac
      841 atcgtccaac atattggcag aactttcttg aatcatcgag tgaaagaaac cacggtacga
      901 cttaaaggaa attcccactc tcaacgaggg ttagggaaaa aattgaagcg ctattggaaa
      961 ctcctacaaa aagaagaagc aaagttaaac tatgaaaaac gggtttggcg tgccagtttt
     1021 aaagattatt tgactgaaag tgagattgcc gatcgactgt tagctgcttg tcccaactta
     1081 cgccaaggct atcagttata ccaagacatt ctttatgcgg taaagaaaag agatcagtca
     1141 ctatttgagg attgtttaac tagagacatt agcggtctgc cagaaaccta tacaaccact
     1201 ttacgaacgt ttaaaaagtt tctgccacag atccaaaatg cgcttcacta cagctattca
     1261 aacggaccat tggaatgctt aaacaaccac atcaaagtat taaaacgcaa tgcgtacggc
     1321 tttcgcaact tttacaattt caaactacga attatgattc gtcatggcaa aacattttta
     1381 accaaataaa cagaacagaa agaggttttc ttctttctgt tctgtcc
//
LOCUS       DAFBSV010000166         1423 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.175, whole genome shotgun sequence.
ACCESSION   DAFBSV010000166 DAFBSV010000000
VERSION     DAFBSV010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.175"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            98..1390
                     /locus_tag="LLB18_002758"
     CDS             98..1390
                     /locus_tag="LLB18_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBK5245710.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
BASE COUNT          463 a          292 c          257 g          411 t
ORIGIN      
        1 acaccagcat cttttttatt ttccaaaaca tatagaaaag acaccttgaa atcctttaga
       61 attaatttgg cgaaccaacc caaaaggagg aatcaagatg tcttacactc accttatcaa
      121 agaaacatta gatattctag acttatcagt tacttttaac gaaaattgtc tcacaaaaga
      181 aaaatacaaa gggcaaatct gtcatattta tcgtggaaac ttgatttata cagcccaaga
      241 atgcatccac tgtaaacacc agattgcttc agatattgtg cgttggggta caacaaccgt
      301 ccggttgtta atgaacgatg tttctgaata ccgtacctac ctcgaattga aaaagcaacg
      361 cttcaaatgc aaagcttgtc agcggacctt tgtcgcagat acttctgttg cgaaaaaaca
      421 ttgtttcatc agtgagaaag tccgctggtc tgtcgtgact cgtctgaaaa aaaatacctc
      481 aatgacagag atcgccgctc agaaaaatct atcggtctct tctgtttacc gtattatgaa
      541 gcgattttat cgtccgttga atccttttcg gacaccgtta cctaaggtac tttgttttga
      601 tgaattcaaa tcagttcggg gtgtttcagg tgctatgagt ttcatcatga tggatggaca
      661 aacacagcgc ttattggaca ttgtcgagaa ccgacaactg ccttttttaa aacgttattt
      721 tagtcatttt tcacgagaaa ttcgtgaagc ggtcgaatgg atcgtgattg atatgtacgc
      781 tccttatgta tcgctcgtta aaaagctgtt tccaaaagca cagctgatta ttgaccggtt
      841 tcacatcgtc caacatattg gtcgtacctt tcgcaatcat cgaatcaaag aaacgaacca
      901 actattaaaa agcaaagaac aaaaacacta tcaattaggt aagcaattaa aaagatactg
      961 gaaacttctt caaaaagatg aacgcaagct tgattatact cgacgccttt ggcgacctgg
     1021 cttcaaagct catttaacag agaccgatat tgtggatcgc ttactgaaag ggagccctgc
     1081 tttgcgtgta ggctatcagt tatatcaaga ctttctttac gctgtaaagg aacgagacta
     1141 cgtatcgttt gaagaactac ttaccaataa tatcatgctt cccgaaggct atcagacgac
     1201 cttgagaacg ttccagaaat ttctgccaca aatcaaaaat gctttacaac aaagttattc
     1261 aaatggccca cttgaatgtc tgaacaacca tatcaaagtg ttaaaacgaa atgcatatgg
     1321 ctttcgtagc ttttataatt tcaaattgcg catcatgatt cgtcatggca acgcattgat
     1381 tttcaactaa aaaagatcaa gaggaactga tccacttgat ctc
//
LOCUS       DAFBSV010000167         1423 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.176, whole genome shotgun sequence.
ACCESSION   DAFBSV010000167 DAFBSV010000000
VERSION     DAFBSV010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.176"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..106
                     /locus_tag="LLB18_002759"
     CDS             <1..106
                     /locus_tag="LLB18_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBK5245711.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            complement(359..508)
                     /locus_tag="LLB18_002760"
     CDS             complement(359..508)
                     /locus_tag="LLB18_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245712.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            970..1182
                     /locus_tag="LLB18_002761"
     CDS             970..1182
                     /locus_tag="LLB18_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245713.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
BASE COUNT          523 a          213 c          237 g          450 t
ORIGIN      
        1 cgcatctaaa cgaaataata ttcctagaaa atcactggat tatcgaacac ctttggaagt
       61 atttttgagt tacgtaagta ttgatgatct gtctaactta atttgacaat taagattata
      121 ttaaatatta tacagataat aacggaatat tatcatcgaa acagctaaca aaattgtcat
      181 aaaaaacgag atggttgata ttagaacttg tgtttttgtt taggtctaga gataaagaga
      241 gacaatttcc aaatatatgt aatgaataca aaaagacgtt tgtcgcggat taccgttaca
      301 aacgtctttt attgattttc cgagatctca tcagtcgcca tttggaatgg ttcactcctt
      361 atctagattc gtttaatgct cggactgctt gttcgattgt aataccaaac gcaacgttat
      421 tttcgttttg tgcatcaatc gccataaaac ggttagaagt tgtatcaaaa gctacgcggt
      481 attgcatatt tgtttttgta aacgtcataa aattcatctc ctttgtaatg taatttagtt
      541 cttgaaagtt tcctttaaac tttcgaactt ataccaagtt tagcatcgta cgttttttga
      601 tgcaattaaa aagcatttat cattttcctt atttattttt tcttaaatgg tttagctatt
      661 ttcttttaat ccgataagta gcccaatcat caaggttaca aatactattg cttgaatata
      721 aatcatatgc tcacctcttt ataaataact tagcaatata aagaaaaaaa cgcacgaaca
      781 acataggaat ataaacaaac gtttttgtca caacgtctaa gatcgtgtta aaaaatagtt
      841 atctaaaaag cagaaagata ctcaaaataa aaaataaaaa aatggataaa aacgttttca
      901 aatacaaggt aatttgttat tataaaataa agaaaaaaca aaataaaaat aaagaaaaga
      961 gggaatgaaa tggtaaaagc agaagtagga agatcttata tatgcaaacc gatcggagta
     1021 tctcatgaac taatcggctg tattgaacgt acatatatca acacggctgt cgtgtatgtt
     1081 gaaagttatg accaacgaga ctatcaactt atcaatgaaa gcaagtatcg catgctcgta
     1141 aaattctgtg atattagcgc acctgctgaa ttggtttctt aaacagtatt tttgagaatt
     1201 cgcaagaact cccttataat ataaataaag acagaaggga gcgagaagat atgccaaaaa
     1261 gaaaaagttc agggaaaatg ggaattattc ttgcagtgat ctctgcaatt cctgctattt
     1321 tagctattgt tcgtgcgatg aaggaatcaa gagaaagtta agcacacatt atgagcgtca
     1381 aacaaaaaac gcatatacct gcggtggcag gttatgcgtt ttt
//
LOCUS       DAFBSV010000168         1390 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.177, whole genome shotgun sequence.
ACCESSION   DAFBSV010000168 DAFBSV010000000
VERSION     DAFBSV010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1390
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.177"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(<1..1225)
                     /locus_tag="LLB18_002762"
     rRNA            complement(<1..1225)
                     /locus_tag="LLB18_002762"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          312 a          391 c          269 g          418 t
ORIGIN      
        1 accaatacac ctaaaggtgt actccacagc ttcggtaata tgtttagccc cggtacattt
       61 tcggcgcagg gtcactcgac tagtgagcta ttacgcactc tttaaatggt ggctgcttct
      121 aagccaacat cctagttgtc tgtgcaaccc cacatccttt tccacttaac atatattttg
      181 ggaccttagc tggtggtctg ggctgtttcc ctttcgacta tggatcttat cactcacagt
      241 ctgactcccg gatatgaatg aatggcattc ggagtttatc tgaattcggt aacccgagat
      301 gggcccctag tccaaacagt gctctacctc catcattctc aattccgagg ctagccctaa
      361 agctatttcg gagagaacca gctatctcca agttcgtttg gaatttctcc gctacccaca
      421 cctcatcccc gcacttttca acgtacgtgg gttcggtcct ccagtgcgtt ttaccgcacc
      481 ttcaacctgg acatgggtag atcacatggt ttcgggtcta cgactacata ctcaaacgcc
      541 ctattcagac tcgctttcgc tgcggctccg tctcttcaac ttaacctcgc atgcaatcgt
      601 aactcgccgg ttcattctac aaaaggcacg ccatcaccca ttaacgggct ttgacttgtt
      661 gtaggcacac ggtttcaggt tctatttcac tccccttccg gggtgctttt cacctttccc
      721 tcacggtact ggttcactat cggtcactag ggagtattta gccttgggag atggtcctcc
      781 cggattccga cggaatttct cgtgttccgc cgtactcagg atcctcctag gtgtcttcca
      841 catttcgtct acggggtttt taccctcttt gactgacttt tccaagtcat tcgactatct
      901 gaaagaacta ccatattgga gtcctacaac cccaacaagc aagcttgctg gtttgggctt
      961 ttcccgtttc gctcgccgct actcagggaa tcgaattttc tttctcttcc tgcaggtact
     1021 tagatgtttc agttctctgc gtctacctcg aatgtgctat gtattcacac aatcgtaaca
     1081 tcctattaaa gatgttgggt tcccccattc ggaaatctct ggatcatagc ttacgtacag
     1141 ctccccaaag catatcggtg ttagtcccgt ccttcatcgg ctcctagtgc caaggcatcc
     1201 accgtgcgcc cttattcact taaccttatc aaccttacgg ttgggttttg atccttcttc
     1261 tagcgataga agttagatca agaaaataag caattgaact tattaaaaaa ctctatccag
     1321 ctcacaaatc agcctgtacg gcaaaaagat cgatcgtctc ataaaatcaa agattttatg
     1381 gccgtccgcc
//
LOCUS       DAFBSV010000169         1370 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.178, whole genome shotgun sequence.
ACCESSION   DAFBSV010000169 DAFBSV010000000
VERSION     DAFBSV010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1370
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.178"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            35..1336
                     /locus_tag="LLB18_002763"
     CDS             35..1336
                     /locus_tag="LLB18_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBK5245714.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          446 a          275 c          253 g          396 t
ORIGIN      
        1 gaatcaccac aacacaatca aaggagcgtt ctgtatgcct gatcttcatc atatcaaact
       61 actacttgga atcaaagata aaaacatttt catcacaaat gtggaatcga agagcattaa
      121 gaatatcaag agtcttgttg tttctgcgac gttaagtaaa gaaattcgtc gctgtccttt
      181 gtgtaaacag atgaatcatg aaggcatgat cgttaagaac ggaaagaaaa aatcgctcat
      241 tcaacttaat aaatgtgcga accaactgac ttatcttgct ttagcgaaac aacgctacca
      301 ctgtcgtggc tgccacacct attttacggc gaatacctac attgtcgata gaaactgctt
      361 tatcgctaaa caagtgcgct ataaaatttt agaagagcta actgaaaaac aagcaatgac
      421 gacaattgct aagcattgcg gcgtttcttg gtcgaccgtt tctcggacac tcgcttctct
      481 gatccccatg acaaaagtaa aaagaaattg gttaccgcgt tgtttattaa tggatgaatt
      541 tcgttcactg aaaaatcaag tcggtcccta ctccttttct tgtatggatg gcgatactgg
      601 aaaattactg gatattcttc cttcacggaa gaaaaaggct ctcgtttctt attttatgca
      661 atttgaacga cgcgcacgat tgaaggtaaa ggtcatcgtg acggacatga atgtttctta
      721 tgcctctctg ataaaggaat gttttccaaa ggcaaaactc gttgtggatc gttttcacat
      781 tgtcaaacat ctcattcgta aatttgagga tattcgcgta cgaatcatga aaagctttga
      841 tcgaaacgat ccaacacaag ccaaatatta tcgacaatta aaggcgttgt ctcggcttct
      901 gatcaaacga caggacaagc ttgtttatga caaatggacc aaatggcgca attttggttg
      961 ggcgtatctc accgaaagtg aagtggtgga tcgtctgctt tcgatctctg acgaattacg
     1021 aatcgcctat ttttactatc aagaaattct tcaagcgttt cacgacaaag aggcggacac
     1081 tttctttaaa cttgtaagaa cgatgcccaa ttccgttcca aaagaactgc attctataaa
     1141 aaaagctttt ataaactatg aatccggcat tcgtttagcc ctcgaattgc cttattcaaa
     1201 tgccaaaata gaaaatctgc atacccacat caaagcattg aaacgagtcg cttatggctt
     1261 tcgaagcttt cggaaaatga agaccagaat tttcttacta aataatctga ttacctatga
     1321 atcaaaaaac atctaaagta gaaaaggaat tctaccttag atgttcttat
//
LOCUS       DAFBSV010000170         1368 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.179, whole genome shotgun sequence.
ACCESSION   DAFBSV010000170 DAFBSV010000000
VERSION     DAFBSV010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1368
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.179"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            82..>1368
                     /locus_tag="LLB18_002764"
     CDS             82..>1368
                     /locus_tag="LLB18_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HBK5245715.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLIN"
BASE COUNT          467 a          263 c          257 g          381 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat taatcaat
//
LOCUS       DAFBSV010000171         1367 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.180, whole genome shotgun sequence.
ACCESSION   DAFBSV010000171 DAFBSV010000000
VERSION     DAFBSV010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1367
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.180"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            26..1365
                     /locus_tag="LLB18_002765"
     CDS             join(26..467,467..1365)
                     /locus_tag="LLB18_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HBK5245716.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYFKKVRNLDSRTRF
                     EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPDKYSKIKQEITAIVK
                     ESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKN
                     VLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEE
                     MLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENF
                     FGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          573 a          176 c          237 g          381 t
ORIGIN      
        1 aatctaatta aaaggggtgc tttttttgcg gaaatataca tttgttttta agaaaaaagt
       61 agtttcagac tatttaaata acgaaggcgg ctacaaatat cttgcacata aatatcaaat
      121 aaatcgtaca ctggttagac attgggtaag gatttataac tatcatggtt gggaaggctt
      181 ggttggaggt ggcaaaagct acactacaaa atttaaactt gatgttatag aatatatgga
      241 aacaaatggt ctttctatcc aagaaactgc taaaaaattt aatatcggtt caaatagaac
      301 tctaagtaaa tggatagagc aatatgaaga aggcggtgct tcttcacttg agagccaaaa
      361 aaggggcaga aaaattagta tgaattccaa gctaaacatt cctaaaaaac ttaaagatga
      421 gtctcttgaa gaagaagtta ttcgtttaag agcagagaac gcatatttaa aaaagttaga
      481 aaccttgatt caagaacaag atttgagcaa gaagaaatca aggttaaaac aatccttcag
      541 ctcaaaaaag aatttaaatt gaatctatta ctttcaattg cacaattagc gaagtcaact
      601 tattattact gggtaaaaaa attagataag ccagataaat atagcaagat aaagcaagaa
      661 attacagcga ttgtaaaaga atcaagaaac tcttatggtt atcgtagagt cactttagcg
      721 ttaaagatga aaggatatac aatcaatcat aaaacagtta gaaaattaat gtcccaaatg
      781 ggacttacct gtcaaatccg aataaagcga tataaatctt ataaaggaac agtaggaaaa
      841 attgccaaga atgtgttaaa acgaaatttt tcagtagata cacccaataa aaaatgggtg
      901 acagacgtca ctgaattcaa gataaaagga agaaaaatct atctatctcc tatacttgat
      961 ttatttaacg gagaaataat tagttatagt atatcaacta gtccaacata taaactgatt
     1021 gaagaaatgc ttcaacaagc aattaaaaaa aagggaactg agggttcact gattctacat
     1081 tcagatcaag gatggcagta tcagatgcca caatatcaaa aaaaattaaa agagaataac
     1141 attattcaaa gcatgtctag aaaaggaaat tgcttagata attctgtaat agaaaatttt
     1201 tttggtgtgc ttaaatcaga gtttttttat cgagaaaaat tccgatcaat tgagatattt
     1261 caaagtaaat taaatgagta tattaggtgg tataataaca aaaggataaa actaaagtta
     1321 aatggactat ctccagtaga atatcggaaa cagtccatta aatagtt
//
LOCUS       DAFBSV010000172         1355 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.181, whole genome shotgun sequence.
ACCESSION   DAFBSV010000172 DAFBSV010000000
VERSION     DAFBSV010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.181"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..1355
                     /locus_tag="LLB18_002766"
     rRNA            <1..1355
                     /locus_tag="LLB18_002766"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          362 a          295 c          415 g          283 t
ORIGIN      
        1 caagctgtga tggggaggga aataatagta ccgaagttcc tgatgtcaca ctgccgagaa
       61 aagcttctag tgagaaaaca gcggcccgta ccgcaaaccg acacaggtag tcgaggagag
      121 aatcctaagg tgagcgagag aactctcgtt aaggaactcg gcaaaatgac cccgtaactt
      181 cgggagaagg ggtgctgatc atacgatcag ccgcagtgaa taggcccaag cgactgttta
      241 tcaaaaacac aggtctctgc aaaatcgtaa gatgaagtat aggggctgac gcctgcccgg
      301 tgctggaagg ttaagaggag tgcttagcgc aagcgaaggt acgaattgaa gccccagtaa
      361 acggcggccg taactataac ggtcctaagg tagcgaaatt ccttgtcggg taagttccga
      421 cccgcacgaa aggcgtaacg atttgggcac tgtctcaacg agagactcgg tgaaatttta
      481 gtacctgtga agatgcaggt tacccgcgac aggacggaaa gaccccatgg agctttactg
      541 tagtttgata ttgagtgtct gtaccgcatg tacaggatag gtaggagccg tagaaatcgg
      601 aacgctagtt tcgatggagg cgctggtggg atactacccc tgcgttatgg ccactctaac
      661 ccgcaccact aatcgtggtg ggagacagtg tcagatgggc agtttgactg gggcggtcgc
      721 ctcctaaaag gtaacggagg cgcccaaagg ttccctcaga atggttggaa atcattcgaa
      781 gagtgtaaag gcagaaggga gcttgactgc gagaccaaca agtcgagcag ggacgaaagt
      841 cgggcttagt gatccggtgg ttccgcatgg aagggccatc gctcaacgga taaaagctac
      901 cctggggata acaggcttat ctcccccaag agtccacatc gacggggagg tttggcacct
      961 cgatgtcggc tcgtcgcatc ctggggctgt agtcggtccc aagggttggg ctgttcgccc
     1021 attaaagcgg cacgcgagct gggttcagaa cgtcgtgaga cagttcggtc cctatccgtc
     1081 gcgggcgttg gaaatttgag aggagctgtc cttagtacga gaggaccggg atggacttac
     1141 cgctggtgta ccagttgttc tgccaagggc attgctgggt agctatgtag ggaagggata
     1201 aacgctgaaa gcatctaagt gtgaagccca cctcaagatg agatttccca tttctttaag
     1261 aaagtaagat ccctgagaga tgatcaggta gataggtcag gagtggaagt acagtgatgt
     1321 atggagcgga ctgatactaa tcgatcgagg actta
//
LOCUS       DAFBSV010000173         1332 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.182, whole genome shotgun sequence.
ACCESSION   DAFBSV010000173 DAFBSV010000000
VERSION     DAFBSV010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1332
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.182"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            50..>1332
                     /locus_tag="LLB18_002767"
     CDS             50..>1332
                     /locus_tag="LLB18_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBK5245717.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTK"
BASE COUNT          419 a          289 c          265 g          359 t
ORIGIN      
        1 aatcctttag aataaagtcg acgaaaacca ttcaaaggag tgtttcaaga tgtcctattc
       61 agagtttacc aaagagttac tagatattct agacctaaat cttacctttc atgaagatgc
      121 ctttcgcaaa gagcgcatta atgacgaaac atgttttgtt tttgatggca cattgaccta
      181 tcaaccagag gaatgcttcc attgccacta tcaaaataag caaacgatca ttaaatgggg
      241 ctggaaaaaa gtatccatct tattgaatga tgtcagtaac tacaagacca ttgtgcggat
      301 taacaaacag cgcttcaaat gtaaacactg tggaaagact tttttagcag aagattcagt
      361 tagcgatcgt cgctgctcca ttgcccgcag agtcaaacaa gccattcttg agctattaag
      421 tgagcctatt tctatgtctt tgattgcacg tatgaagcac atttctccga ccactgtcat
      481 tcgaatactt cgcagccttc ggcctaaaac cgtttctttg aaccagccgt taccagaagt
      541 ggtgtgtttc gatgaattca aatcggtgaa aaacgtctcg ggagccatga gctttgtcat
      601 gatggacggc aagacccatc aactgattga tattgtggaa aatcggcaac tcaatccttt
      661 acgcgactat ttcttgcgct accctagaaa agtccgtgaa caagtacgtc tagtggtttc
      721 agatttctat acaccctatc gcacattggt gaaagagtgt tttccgaatg cccgaatcgt
      781 cgccgatcgc tttcatatta gccaacacat cggtcgggcc tttaccaacc accgaattca
      841 agtaatgaag acctttaaaa aaggggatcg tcggtcgaag cacttaaaga aatactggag
      901 actacttcaa aagaatgcgt gggaattgaa tggtcagcat cgctactggc gtccgtcatt
      961 tcgagatcat ctgacagaag cggagatagt cgatcggcta ttatattatg atgactcctt
     1021 aaagcgaggc tacgaagtct accaggtttt tctttccgct atcagaagac aagatgttcc
     1081 tgaattcgtc gcgctcctaa aagaagacta caaggagttg ccagagcact atcaaccagt
     1141 gttcacgacc ttcaagaaat atcgaacaga aatcaaacga gcgttgcgag ttccctattc
     1201 caacggccct atagaatgtt tgaacaacca tatcaaagta ctaaaacgaa ttgcctatgg
     1261 ctttagaaac tttcaaaact accgagaacg aatcttttta tatcgaggaa aatatttcaa
     1321 gaaaactaag aa
//
LOCUS       DAFBSV010000174         1312 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.183, whole genome shotgun sequence.
ACCESSION   DAFBSV010000174 DAFBSV010000000
VERSION     DAFBSV010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.183"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            129..>1312
                     /locus_tag="LLB18_002768"
     CDS             129..>1312
                     /locus_tag="LLB18_002768"
                     /inference="COORDINATES: protein motif:HMM:NF033550.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBK5245718.1"
                     /translation="MSMNHFIKQLFTIKDSNIQIQSFEETFYKSRKSIVIEGTLIRTY
                     RRCPCCKDSTKQIVKNGKKISMILLNRSGNKRTYLRLKKQRYLCRACKKYFTARTYLV
                     TPFCFISKQIHYKILEELTERQSIKAIGKHCDVSVTTVQRTLSALSSDIRQNLEYLPR
                     CLLFDEFRSLSTWHGKFSFSCMDGETGKLFEILPSRRKKDLVAFFMRFSLKARLGVHY
                     IVTDMNAPYFSLVKECFPNAQVIVDRFHIVQHLNRFFDAVRKRVMKTLDQKDPIQAKQ
                     YRQLKSLFKLLLKSEDRLDYNTLTKRRNFNWRLLTETEVVDRLLKISPELKTAYRYYQ
                     DLLTAYQEKDPDTFFQLLRAMPGEVPLELHHIKKAFFKYEKGIRLALLKKYSNARLEN
                     LHT"
BASE COUNT          411 a          263 c          236 g          402 t
ORIGIN      
        1 gctctataat ttctaggact gatggaaatt ttctatctgt cctagttttt ttgtaaaaaa
       61 acaaaaagac atacaaaatt tccggtagaa tagagtctcc tacaacatca ttctggggga
      121 attcttgtat gtccatgaat cattttatca aacaactctt tactattaaa gactcaaata
      181 tccaaattca atcctttgaa gaaacttttt ataaaagcag aaaaagtatc gttattgagg
      241 gaactctgat ccgtacctac agacgttgtc cgtgttgtaa agattctaca aagcaaatcg
      301 ttaaaaatgg caagaagatc tctatgattc tcctgaatcg tagcggtaat aaacggacct
      361 atcttcggtt gaagaaacag cgatacctct gccgagcatg taaaaaatat tttaccgctc
      421 ggacgtatct cgttacccca ttctgcttta tttctaagca gattcattac aagatcttag
      481 aagaattgac agagcgtcaa tctataaaag caattggtaa acattgcgat gtttctgtga
      541 caactgttca gcggacattg tccgccttgt catcagatat ccgtcagaat cttgagtatt
      601 tacctcggtg tctattattc gatgagtttc gttctctttc tacatggcac ggtaaatttt
      661 ctttttcttg tatggacggt gagaccggga aactgtttga gatcttacct agccgccgta
      721 aaaaagatct cgttgctttt ttcatgcgtt tttctctcaa agcgaggttg ggtgtacatt
      781 acatcgtaac ggatatgaac gctccttatt tctcactagt taaagagtgt tttccaaatg
      841 cacaagtgat cgtcgatcgg tttcacattg ttcaacatct gaaccgcttc ttcgatgcgg
      901 ttcgaaaacg tgtgatgaaa acacttgatc aaaaagaccc aatacaagct aaacagtatc
      961 gccaattgaa atccttattc aaattacttt taaaatcaga ggatcgttta gattacaata
     1021 cactaacgaa aagacgcaat ttcaattgga gactattgac tgaaacagaa gtagttgacc
     1081 gccttctaaa gatttctcct gaacttaaaa cagcttatcg ttactaccaa gacctgctta
     1141 ctgcgtatca ggaaaaagat ccagatactt ttttccagct gcttcgagca atgcctggag
     1201 aagttccatt ggaactgcac catatcaaaa aagccttttt caaatacgag aaagggattc
     1261 ggctggcatt actgaagaag tattcgaatg cacgactgga aaatctccat ac
//
LOCUS       DAFBSV010000175         1236 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.184, whole genome shotgun sequence.
ACCESSION   DAFBSV010000175 DAFBSV010000000
VERSION     DAFBSV010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1236
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.184"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..104
                     /locus_tag="LLB18_002769"
     CDS             <1..104
                     /locus_tag="LLB18_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HBK5245719.1"
                     /translation="GTVEFPIEEGALIIATVDDPKQNVFTLEKVGVI"
     gene            104..724
                     /locus_tag="LLB18_002770"
     CDS             104..724
                     /locus_tag="LLB18_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245720.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            728..1177
                     /locus_tag="LLB18_002771"
     CDS             728..1177
                     /locus_tag="LLB18_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245721.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKVKLDGLANITFEKVGTV"
BASE COUNT          446 a          200 c          280 g          310 t
ORIGIN      
        1 ttggaactgt agaattcccg attgaagaag gagccttgat catcgcaacc gttgatgatc
       61 caaagcaaaa tgtgttcact cttgagaaag tcggggtgat ctaatggcta aaactaaacg
      121 aatgatggaa acggatgaaa aaacaggtgt acaacgccaa ttctttccaa tcacacatgc
      181 ttccgcagtt cttgggttag aagaaataat agcaggagaa gcaacagttt tatctgttaa
      241 tggaaaaatt ggagccgtcg tcattactaa agaagatttg ggattagaga atgttctcac
      301 agaattaccc tatgcaagtg aagaagatga cggcattatc acggcagaaa tgtatcaaaa
      361 aattttaaac agtggagaag gtgactacgt gttgccagtt gccactatcg accgtttggg
      421 tggcataaaa gttggtgaat tattgacgat tgatgagaca gggaaagtct ctgcagtcag
      481 acaatctgat gtcaattttt cgctggagtt aaaagaaaaa ctcgattcac tgaaaaatta
      541 tactgctgga gaaaacatca ctattgatga agatggaaca attagttcta caggtggtag
      601 tgggactggt ggtgtcaatc agtcatatgt agatcaaaaa ttccaagaag ctgtaaatca
      661 agcagaaaat tacacaaacg aaagaattcc aaattttact tttgaaaaaa ttggggaggt
      721 atagagaatg acagatatcg taaaaataaa acaaagcaat gtacaggttt atccacaaac
      781 tcattggaat gctatagaag gcaaaccaac aacggtgaag ggagataaag gcgatcctgg
      841 ccaagcagca acaattacca taggaaccgt ttctagtggt tcaaccgctt ctgttacgaa
      901 tgtaggaaca tcatctgcag ctagatttaa ttttgtttta ccaaagggag ataaaggtga
      961 tcctggaata aatgccacaa ctacagctgt agctacaact acagcaaatg ggttgatgtc
     1021 gtccacagat aaaactaagt tggatggaat tgcagctgga gcacagaaaa atccaggtaa
     1081 tgctacaact acgacagcag gtttaatgtc agcaaccgat aaagtgaaac ttgatggatt
     1141 agccaatatt acatttgaga aagtggggac ggtttaatgg ctgatattgt tcaattaaaa
     1201 gaagacggag ttgctaaata cttaaaaacg catgta
//
LOCUS       DAFBSV010000176         1231 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.185, whole genome shotgun sequence.
ACCESSION   DAFBSV010000176 DAFBSV010000000
VERSION     DAFBSV010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1231
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.185"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            430..963
                     /locus_tag="LLB18_002772"
     CDS             430..963
                     /locus_tag="LLB18_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HBK5245722.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT          390 a          227 c          230 g          384 t
ORIGIN      
        1 ttttcgtttg gttggactta ttaccgcaga tgcaagcttt tgaacaccgt ttattgagaa
       61 gttgtgaaat cagcgtcctg acctgagtat tagagaaaca aatggcaaaa tagttcctca
      121 tattttgcta ttttttgagc taataccgag ggtcagctga ttgaacaccg tttagtggag
      181 aagttgtgaa aaagtcgcct actttcgagt cgtaagaaat ttttttgaaa atggttcctc
      241 acaactttgc ataaatttga cttaataccg agaagtcatg atccccatct aactccaaat
      301 cacaaggaat gagttcaaaa actagctttt ctcaacaaat attacataaa aaattctatg
      361 ttttttgtta aatttatttg cttttttcaa aagtatgtta cagtaatttc ccaaggaggt
      421 tttacagaaa tgaattttgt tgccatggat tttgaaactg ccaatcatca gccttatagt
      481 gcttgttctc ttgcgctagt catggtaaaa aatagccaga tcgttgatga attctataca
      541 ttgatacagc ctgagactcc ttttttctgg cgaaatgtcc aaattcacgg aatccatcaa
      601 gaagacgtac gcaatgcgcc gaaattccca gaagtctggc aaactatcca accatatttt
      661 caaaaaaatc gtttagtcgt tgcacataat gctgcttttg atacaaaggt cttagcggga
      721 tgcttagatt attatcatct tgaacagcct aattatcttt ctttatgtac agtgaaaagt
      781 agccgtcgcc tgtttcctga atttccaaat catcgattga acactgtgtg cgaaaatttg
      841 aacatccaat tagatcatca ccatgatgca ttggaagata gtcgtgcatg tgcggaaatc
      901 ctgctttatc aagaaaaaaa attcgggaca gatccattga aaaaacttgt gactataaag
      961 taaaagaata cttatgaaac acacaaagag gtcgtgagcc tgccgtttca ctccgagtca
     1021 caaggagcaa tttcaaaaaa tagcttctca tgtttattaa atattgtgac tggtgaccga
     1081 ggagctggca ggagaacacc gtttattgga gaggttgtga aaaagctgtt ctgcatcaag
     1141 taataagaac agccaaacaa aaatagcttc tcatattttt catttggttg gacttattac
     1201 cgcagatgca agcttttgga caccgtttac c
//
LOCUS       DAFBSV010000177         1185 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.187, whole genome shotgun sequence.
ACCESSION   DAFBSV010000177 DAFBSV010000000
VERSION     DAFBSV010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1185
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.187"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..1068
                     /locus_tag="LLB18_002773"
     CDS             <1..1068
                     /locus_tag="LLB18_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBK5245723.1"
                     /translation="GMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSRMF
                     DENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHFLE
                     NLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKGRF
                     KQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQVIV
                     VIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQSQN
                     TPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKFTR
                     LVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          417 a          234 c          208 g          326 t
ORIGIN      
        1 ggcatggagt caacgtccat gtacagcttc catccttcca tgttttttca tgaagatgag
       61 aaactaaaga agctcaacac acttgtaacg attgaaaatc cttttcgggt gaaacaattt
      121 agtcgcatgt ttgatgagaa taaaactgat cgaaacgatg cattaagaat cgctgatttc
      181 ttgcgtattc aacgattcac aacttcccct atcaaagaag agaaatacat ggccttacag
      241 cgtttaacac gtactcgcta tcaacttatt aagcaattga ttcgtacaaa gcaacatttt
      301 cttgaaaatc taacgtacaa atgtaatacg cttgctcgag aaatgcgaga cgaatcgacg
      361 agtcttttta gtgcaaccct catttcactc atgacggaag atttcacatt ggatgaactt
      421 gctgagcttc ctttagaagc tttctgtgat ttacttcaag aaaaaggaaa aggccgtttc
      481 aagcaaccag aaaaaatcgc taaagcaatt caacgtgcaa ttaccatgag ttaccgccta
      541 ggtgctcttg cacaagaatc aattaatgtt gttttaagtg ttctcgtacg agaaatacga
      601 gcacttgaaa aaaatatcaa agaattagat aaagccatcg aacaagtaat tgttgtcatt
      661 ccagaatatc aatgcttaac cagtattcca ggcgttggta aagtctatgc tgccggttta
      721 atcgctgaaa ttggtcaaat cgaaagattt gaagatcaga caaaattggc aaaatacgct
      781 ggattaagtt ggaaagtgaa ccaatctgga aactatcagt cgcaaaatac acctctgaca
      841 aaacaaggaa atcgatattt tagatactac ttagttgaag ctgccaactc tgtaaaaaat
      901 tatcttcctg aatacaaagc tttttatcaa agtaaatata aggaggttcc aaagcatcaa
      961 cacaaacgtg cactcgtcct aaccgcaaga aaatttacgc gtctggtgga tacgctacta
     1021 cgtaaacacc aactctatac gccaccaagg agtgtgatag agaaataaca atccgttatt
     1081 gacgcaaatc cttgaatcaa cccgaaaaaa atttgatttt gatcgggtct agtttcgtgc
     1141 gcttcaaaac atattactca ataaagaaaa tcttaaattt catct
//
LOCUS       DAFBSV010000178         1156 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.188, whole genome shotgun sequence.
ACCESSION   DAFBSV010000178 DAFBSV010000000
VERSION     DAFBSV010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1156
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.188"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..1087
                     /locus_tag="LLB18_002774"
     CDS             <1..1087
                     /locus_tag="LLB18_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBK5245724.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT          416 a          203 c          225 g          312 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaaaccac cggtggcaaa ccggtggcaa atccatgtaa
     1141 acatggttta tttttt
//
LOCUS       DAFBSV010000179         1140 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.189, whole genome shotgun sequence.
ACCESSION   DAFBSV010000179 DAFBSV010000000
VERSION     DAFBSV010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1140
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.189"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(<1..181)
                     /locus_tag="LLB18_002775"
     CDS             complement(<1..181)
                     /locus_tag="LLB18_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA adenine methyltransferase"
                     /protein_id="HBK5245725.1"
                     /translation="MSKYCLFLIVIYYLTGGNNSMSRFFKFGKLHVTKGNGDKLLDIL
                     LTASKKLKRSLAPTGN"
     gene            complement(126..863)
                     /gene="erm(B)"
                     /locus_tag="LLB18_002776"
     CDS             complement(126..863)
                     /gene="erm(B)"
                     /locus_tag="LLB18_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBK5245726.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(988..1071)
                     /locus_tag="LLB18_002777"
     CDS             complement(988..1071)
                     /locus_tag="LLB18_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBK5245727.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
BASE COUNT          344 a          185 c          184 g          427 t
ORIGIN      
        1 aattccccgt aggcgctagg gacctcttta gcttcttgga agctgtcagt agtatatcta
       61 ataatttatc tccattccct ttagtaacgt gtaactttcc aaatttaaaa aagcgactca
      121 tagaattatt tcctcccgtt aaataataga taactattaa aaatagacaa tacttgctca
      181 taagtaacgg tacttaaatt gtttactttg gcgtgtttca ttgcttgatg aaactgattt
      241 ttagtaaaca gttgacgata ttctcgattg acccattttg aaacaaagta cgtatatagc
      301 ttccaatatt tatctggaac atctgtggta tggcgggtaa gttttattaa gacactgttt
      361 acttttggtt taggatgaaa gcattccgct ggcagcttaa gcaattgctg aatcgagact
      421 tgagtgtgca agagcaaccc tagtgttcgg tgaatatcca aggtacgctt gtagaatcct
      481 tcttcaacaa tcagatagat gtcagacgca tggctttcaa aaaccacttt tttaataatt
      541 tgtgtgctta aatggtaagg aatactccca acaattttat acctctgttt gttagggaat
      601 tgaaactgta gaatatcttg gtgaattaaa gtgacacgaa tgttcagttt taatttttct
      661 gacgataagt tgaatagatg actgtctaat tcaatagacg ttacctgttt acttatttta
      721 gccagtttcg tcgttaaatg ccctttacct gttccaattt cgtaaacggt atcggtttct
      781 tttaaattca attgttttat tatttggttg agtacttttt cactcgttaa aaagttttga
      841 gaatatttta tatttttgtt catgtaatca ctcctgaagt tattacatct gtaaataaat
      901 acagaagtta aacgatttgt ttgtaatttt agttatctgt ttaaaaagtc ataagattag
      961 tcactggtag gaattaatct aacgtattta tttatctgcg taatcactgt ttttagtctg
     1021 tttcaaaaca gtagatgttt tatctacatt acgcatttgg aataccaaca tgacgaatcc
     1081 ctccttctta attacaaatt tttagcatct aatttaactt caattcctat tatacacaaa
//
LOCUS       DAFBSV010000180         1091 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.190, whole genome shotgun sequence.
ACCESSION   DAFBSV010000180 DAFBSV010000000
VERSION     DAFBSV010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1091
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.190"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="LLB18_002778"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="LLB18_002778"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBK5245728.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          384 a          135 c          187 g          385 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaaact aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgatga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt ttcttgatgt gatatccttg tcttttttgt
     1081 aatgttttta a
//
LOCUS       DAFBSV010000181         1082 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.191, whole genome shotgun sequence.
ACCESSION   DAFBSV010000181 DAFBSV010000000
VERSION     DAFBSV010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1082
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.191"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..275
                     /locus_tag="LLB18_002779"
     CDS             <1..275
                     /locus_tag="LLB18_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBK5245729.1"
                     /translation="NPFVSEYVKRLAKGICQLCQEKGPFIKDGVPYLHCHHIEYLSQG
                     GKDVIENCIALCPNCHARIHELELPDDKEKLLKIVEKRENSFSKIP"
     gene            618..874
                     /locus_tag="LLB18_002780"
                     /pseudo
     CDS             618..874
                     /locus_tag="LLB18_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320124.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
BASE COUNT          375 a          163 c          198 g          346 t
ORIGIN      
        1 gtaatccctt cgtatctgaa tatgttaaac gacttgcaaa aggtatttgt caactttgcc
       61 aagaaaaagg gccatttata aaagacggtg taccttattt acattgtcat catatagaat
      121 atttgtcgca aggtggaaaa gatgtgattg aaaactgtat cgcgttatgt cccaattgtc
      181 atgctagaat tcatgaactt gagttacctg acgataaaga aaaattgctg aagatcgttg
      241 aaaaaagaga aaatagcttt tctaaaatac cgtaatttat ttttatagga caaataagct
      301 aatgtgagct atgccttcta tataagacta agttctatta taagtaacga agtaattctc
      361 gttccttcct gtagtaatat tttttaaata acctataggc ttcttcaaaa gtacatcctc
      421 cagtaaattc taagtactgg aggattcttt ttctagtgtt gctttactca tgaaaaagta
      481 gttggctact tcatcaaaat ttctgaactt ttttaatgta taataaagag ctcgatcatt
      541 tactacaagg atgctagctc ctacattttc acagtttttt agcaagtaaa tttttctaaa
      601 atcacatcag gaaatgcatg agattcttta agaaaggcaa ttatagggct atgattacgg
      661 ttcgtgtaag tgacgccaaa aaagaatggc tttcttatat ggctgaattt tatgggatta
      721 ctttatctga acttctaaaa aactattcga tggaacaact agaagatgaa tacaatcgtc
      781 aaacggctga aattgcccat aaacattgga taagaagtgg gaaaacaaca gtattcatgg
      841 aagaatcctt aatgaatttg gtgggctgga atgacctgcc gtttaaaatt cacgcccgaa
      901 attcagaagc agctctgatt ggcaaatacg tgtattggta gagatagaag ataatcaatt
      961 cgttgttacc gctattcaag tagggcaccg aagaaatgtc tatgattaag agactgttta
     1021 tttttacaaa aaaataataa ctggaatcta gttaaaactc ttgaagtgag agatttgact
     1081 ag
//
LOCUS       DAFBSV010000182         1062 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.192, whole genome shotgun sequence.
ACCESSION   DAFBSV010000182 DAFBSV010000000
VERSION     DAFBSV010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.192"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..>1062
                     /locus_tag="LLB18_002781"
     CDS             <1..>1062
                     /locus_tag="LLB18_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HBK5245730.1"
                     /translation="DLNELFRSHLEKAINTLLRTELTAFLDYEKYDRTGFNSGNSRNG
                     SYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLETTIIHLFEKGVTMSEIA
                     DLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAIFMDATYIPLKRQTVSK
                     EAIYIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDINSRGVQEVLLFITDGLKGMK
                     DTIHQIYPKAKYQHCCIHVSRNIAHKVRVKDRKEICDDFKAVYQANSKEEANTFLSGM
                     IEKWKKNYPKVTQSLIENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQF
                     QNEESLERFLVSIFDTYNQ"
BASE COUNT          388 a          200 c          178 g          296 t
ORIGIN      
        1 gcgatttaaa tgaattattc cgttcgcact tagaaaaagc gataaacaca ctcctacgga
       61 ctgaattaac ggctttttta gattacgaaa aatatgatcg cactggtttt aattcaggta
      121 attcgagaaa cggttcttac tttcgatcaa tcaaaaccga atatggtgaa ttaacattgg
      181 aaatacctag agatcgtaat ggtgagttta aacaacaaac tttaccagcc tacaaaagaa
      241 caaacgatac attggaaacc actattatcc atttattcga aaaaggtgtt acgatgtctg
      301 aaattgctga tttgatcgaa aaaatgtacg gtcatcacta tactccacaa accatgtcca
      361 acatgactaa agttctgact gaagaagtaa atgcctttaa atccagagcc ttaaatgata
      421 agtatgtcgc tatttttatg gacgctactt acattccact aaaacgtcaa accgtatcca
      481 aagaagcgat ttatattgcc attggtatac gagaagacgg cactaaagaa gtactgagtt
      541 atgcgattgc tccaactgaa tcaacatacg tttggaatga gctgctacag gatattaact
      601 ccagaggagt tcaagaagtc ttgcttttta ttacggacgg cttaaaaggc atgaaagata
      661 ctatccatca aatttatcct aaagcaaaat atcagcattg ttgtatccat gtatctcgta
      721 acatcgctca taaagtacgt gtcaaagacc gaaaagaaat ctgtgatgac tttaaggctg
      781 tttatcaagc taactcaaaa gaagaagcga ataccttctt atccggcatg attgagaaat
      841 ggaagaaaaa ctatcctaaa gtgacgcagt cactcataga aaaccaagac ttattaactt
      901 tttatgattt tccacctagc attcgtagaa ccatttactc aaccaatcta atcgagtctt
      961 tcaataagca aattaaaaga tacagccgta gaaaagagca gtttcaaaat gaagaatcac
     1021 tagaacgctt tctagtcagc atttttgata catacaatca aa
//
LOCUS       DAFBSV010000183         1058 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.193, whole genome shotgun sequence.
ACCESSION   DAFBSV010000183 DAFBSV010000000
VERSION     DAFBSV010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1058
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.193"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(36..992)
                     /locus_tag="LLB18_002782"
     CDS             complement(36..992)
                     /locus_tag="LLB18_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245731.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          344 a          176 c          160 g          378 t
ORIGIN      
        1 tagaaaaagc agtcggactt tctaaaagaa gttcactatt cgatcctgtc gatgatttct
       61 tcaggaaaat cgtctatttg cttgtcaatt ttgctgtctt tgtatttctc ttcttggata
      121 gtcaacaaaa tctttgtaag attcccccag tctactgctc ttggcggatc gagccaaacc
      181 actacttgag atgcactttc ttcatataga ttattcctat tcgtgattat aacatccggg
      241 aactcaggct ttcctgcctc tatcacttcc gtgttcagat taatgtacaa gcttaaattt
      301 ttcttgataa attgattata ggcagcacca taagaaaaat cgatgatgat ctttactggt
      361 tcagaaatca gttgaatggg tatgtgattg atcaataata ataaataact gaaaaaaaga
      421 aaaaatttat cttgaagcaa ctctttgcgt tttgacgtta gatcatttat atactctatc
      481 aaatagcaat aaaatgctgg atagttttct ctaaaaaaag aaacatcaag tggaaattca
      541 tcagctttat taatagtgta atgcaaaagt ttaaaatgta ttttggttaa ctctcttcgg
      601 atcaattggc tcgtctcttc tcgcaacaga ttaaactgat tttcaaaact ttcaatgaat
      661 cgttcattca accattcgat tgtttcatct tcattttttc tcaagtattt ttgatccaat
      721 ttatcatgaa gataaagcca agagagtgtc ttattgataa aaataacgga tttttctcct
      781 aatactcctt ttaagtggta aaatcctata tccgaaaaaa atagcgactg attgctagca
      841 atatctaaag aatcagcttg ttcagccaac aggttgattg ctaaaaagtg gaataatttc
      901 tttttttcat aagcagacag aggataatac tgttttaaat cttttaacat tttttctgtt
      961 tttataatta taggtagcgt atacaattcc acaaaactta tctctgttga gttaaaaaga
     1021 ttatataaaa aaagccgaat gtttttagga ttccctgt
//
LOCUS       DAFBSV010000184         1006 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.194, whole genome shotgun sequence.
ACCESSION   DAFBSV010000184 DAFBSV010000000
VERSION     DAFBSV010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1006
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.194"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(128..775)
                     /locus_tag="LLB18_002783"
     CDS             complement(128..775)
                     /locus_tag="LLB18_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HBK5245732.1"
                     /translation="MEQTIKPYQYFFIIREVEQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILDHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
BASE COUNT          280 a          193 c          167 g          366 t
ORIGIN      
        1 agaaaggggc tgtccccaga ctttagtagg cgtcattagc tatctttcgt tagcatttaa
       61 aggcgaacac catcacctat tcacttccat taaaagatag catatttttc tgtaaaaaac
      121 aataaaatta tcgttctttc tttacacgtt cagcaaattc atagaaagga gccaatttcg
      181 ttaactgttg attacattgg tcactatcat gacaaatata attccccttt ttcgtatacg
      241 tgccatcaga acctgctttc gttgtagaaa gaaaaagcga aacattcgat gttttctgac
      301 agattgcaca gattccctta tttatcgttg gtgataaagt accgctaatc ccttttaatt
      361 tttcatcttc gtaatagacc atgaattttt tctgcgtacc tggatcattc cagccgatgt
      421 acgtatgttc ttgcaagtcg atttcattcc aagctggttg tttgagtttt ttcacttttc
      481 ggaataattt ctcgatttgt ggtttgctag gctgcataaa cggctgaacg atttgcttca
      541 gctcctccaa tgctctttct gcttgcgctt ttgtcagttt tacgtctaaa actgtcgtta
      601 aaaatgtatc gatttctggc agttcgtgat ctaatatgtc tcgaatcttt tcagctgcta
      661 gtgcctgaac tgtttgtacc gtttttggat cattgacaga tgagtacgca tttaataact
      721 gttctacttc tcttattata aaaaaatatt ggtatggttt tattgtttgt tccatgattt
      781 taaagtcctt tcttctaacc aaagtgcata ctttgtagaa aaaagtgatc ttctgcaaag
      841 tatgtgttac ctgaagatcc tggactcttt taaataagat acgttttgca tcttatcatc
      901 acccccttta atgcttatta ttctatgtac atgattcatt cgataaataa aagtaaaccg
      961 tatcttgaac agatagtcaa ctgcaaacag aaaaaaggac tgtgac
//
LOCUS       DAFBSV010000185         1002 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.195, whole genome shotgun sequence.
ACCESSION   DAFBSV010000185 DAFBSV010000000
VERSION     DAFBSV010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1002
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.195"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            128..>1002
                     /locus_tag="LLB18_002784"
     CDS             128..>1002
                     /locus_tag="LLB18_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBK5245733.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEEALDHIDF"
BASE COUNT          359 a          153 c          189 g          301 t
ORIGIN      
        1 atatcccata ttttaaaata aaagatagcg taaaatattt tgtgtaaata gaaatttagg
       61 gtagaaaaaa aagtccattc tgtaaaatta aagttaccac acagaaattt tataggagga
      121 ctttctcatg actaaattta ctatagaaat tatgcaaaca ctactcaata aaggggattt
      181 agatgaatta tttcaggatc atttagagcg agcgattaat tcacttctac aagcagagct
      241 aactgctttt ttagattacg aaaaatatga tcgaaatgga ttcaattcag gaaattcccg
      301 taacgggaat tattcacgta catttaaaac agaatatggc gagttgaatt taactattcc
      361 tagagatcgg aatggcgaat tttctcaaca aacactacca gcatataagc gaaccaatga
      421 ttcattagaa acgaccatta tccaattatt tcaaaaaggc attactatgg ctgaaatctc
      481 caaattaatt gaaaaaatgt atggtcacca ctatacgcca caaacaatct ccaacatgag
      541 taaattggtg gctgaagatg ttttagcttt taaagaaaga acgttagaag ccaattattc
      601 cgttatattt atggatgcga cgcatatccc tgtgaagcga cagactgttt cgaaggaagc
      661 agtgtatatt acgattggta ttcgtttgga tggaaccaaa gaagttcttg ggtttactat
      721 tgccccaact gagtctgctt atatttggaa agaagttctt caagatctta gaaaacgtgg
      781 gttagaagaa gttttattag tagtgacaga cggattaagc tgtattgaag aaagtatcca
      841 tagtgtgtat ccgaatgccc aatttcaaca atgttgtgtg catgtatcta gaaatatcgc
      901 tcataaagtt cgtgttcgag gtcgaaaaga aatttgtgag gatttcaaat tggtttacca
      961 agcgaattca aaagaagagg cattggatca catcgacttt at
//
LOCUS       DAFBSV010000186         1000 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.196, whole genome shotgun sequence.
ACCESSION   DAFBSV010000186 DAFBSV010000000
VERSION     DAFBSV010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.196"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            369..1000
                     /locus_tag="LLB18_002785"
                     /pseudo
     CDS             369..1000
                     /locus_tag="LLB18_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          181 c          183 g          294 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaata
      301 taggctctat aatttatggg actgatgaat caaaattgat tcttcagtcc cattgttatt
      361 ttaggtatat gattcgtaca ttgaaagagt tgaaaaacta tcttccgaag ccgtcaaaaa
      421 ggaccctgcc aaaagtattg atggtggatg aatttcgttc gcacgcttca attgtggata
      481 aaatgagctt tatttgtgcg gatggcgaga ctggaaaact cattgatatt ttgcctacac
      541 gaaaattgtc tcgattaaca cactatttta gtcgctgtgc aaatcctgaa gcggtggaat
      601 atttagtgac agatatgaac gccgcctact tccaactgac aaaacgtgtc ttaccaaatg
      661 cgaaagtcgt cattgattgt tttcatatca tcaaacattt gaatcaggcg ttcaatgatt
      721 ttcgtgtaca agaaatgaaa agattacacc agttagggca acgacgggaa gccgagaaag
      781 tgaaaaagaa ctggcgcttt cttctaaaaa accgtcaaaa aatcaatcac tatgattaca
      841 aaacatggcg cagttttcgt gcacctaaat acccgctact cactgaagca atgatgattg
      901 atcgattgct ggcattttca acgcctttaa aggacgccta tacttttttc catgagctga
      961 ccgaagcctt tagagacaag gaatcagact tattttttac
//
LOCUS       DAFBSV010000187          995 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.197, whole genome shotgun sequence.
ACCESSION   DAFBSV010000187 DAFBSV010000000
VERSION     DAFBSV010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..995
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.197"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(<1..908)
                     /locus_tag="LLB18_002786"
     CDS             complement(<1..908)
                     /locus_tag="LLB18_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HBK5245734.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYG"
BASE COUNT          287 a          217 c          166 g          325 t
ORIGIN      
        1 ccatattttt ccaagaagtg ctcttttctt tcacgtgtca attcaagttc agaggcttta
       61 aagatactct tcaactcgtc ttttacatca gaagaaactt tctttggcag cttatcaaaa
      121 atatttctca aaaagtgggc ttggcatctt tgccagctcg cacctaaaaa gttcttgcga
      181 acagccttaa ctaacccttt gtgtgcatca gaaatgacca gttttacacc gaacaaacct
      241 cgttgaacga acgattgaaa aacggtatcc caattatctt ccgattcgcc gtcttgaaca
      301 tcaaaaccaa gaatcgtacg tcgtccatca gaatcaatgc cgataccaat atatacacct
      361 tttgagacaa tacgatgatt ttcccttact ttcatataca gggcatcaca catgaaaaat
      421 ggatattccg agccttctag gctccggttt ctccactcaa aaacaaatgg atccaactgt
      481 ttcatcagat ttgaaacgaa tgatttagaa acagtcgcac catccgttag cagttcaact
      541 gttttagtta ctttgcgagt ggagacacca gaaatgacca tttcaatcat ggcagcgatc
      601 aaagcttttt cgcttcgctg atatctttca aagatagtag gactaaactt accgtctctg
      661 gttcgtggaa catgaagttc taacgtacca attcgagttg taaacgaacg atcgtagtaa
      721 ccatttcttt gtgattgccg ttcttctgaa cgttcatagg catttgcctg aatatattga
      781 tttcgttgtt cttccatcag ctgattaaac atgatagtca taagtgtttt tgcggtatca
      841 ttcgcaccgc tttcgtttat aattgcttga atttcttcgc tttcaaaagt aaaatgtact
      901 tgagtcattg atatcagtcc tattcgagta tgttttctgc aaaaaacatt gtactcctaa
      961 ctgagatcaa tggctttttt gatgcttcac tttta
//
LOCUS       DAFBSV010000188          994 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.198, whole genome shotgun sequence.
ACCESSION   DAFBSV010000188 DAFBSV010000000
VERSION     DAFBSV010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.198"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            55..994
                     /locus_tag="LLB18_002787"
                     /pseudo
     CDS             55..994
                     /locus_tag="LLB18_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT          382 a          166 c          190 g          256 t
ORIGIN      
        1 gacagaaaaa ttaaggtgtg tagactagaa gaaaacatac caggaggaat ttttatgtct
       61 aagagaacac gaagaacttt ttcacaagaa ttcaagcaac aaatcgtcaa tctttactta
      121 gctggaaagc cacgtgtaga aatcattcga gaatatgaac taacggcttc agcatttgac
      181 aaatgggtaa agcaatctaa aacgagtggt tcattcaaag aaaaagataa tcttacgcct
      241 gaacaaaaag aattgttaga actacgtaaa agaaaccagc aattagaaat ggaaaatgat
      301 attttaaagc aagcagcgct gatattcgga cgaagagaca agtaatcgat gcgaataagc
      361 atctttaccc tatatcagcg atgtgcagaa tattaggtct atcacgtcag tcctattatt
      421 atcaatcaaa accaaagaaa gacgaatcag aacttgaaga agtagtcgct gaagaattta
      481 tccgcagccg aaaggcctac ggctcaagaa aaataaaaaa agccttatca aaacgaggca
      541 ttcagatcag ccgacgaaaa attagtagaa tcatgaaaaa tagaggatta aaatcgagct
      601 atactgttgc ttattttaaa gtacatcatt ctacttgcaa tgaagccaaa acgacaaacg
      661 tattgaatcg taaattctta agagacaacc cattagaagc gatcgtaaca gacttgactt
      721 atgtacgagt cgggaaaaaa tggaattatg tctgtttcat tttggatctg ttcaatcgag
      781 aaattctcgg ctattcttgt ggagaacata aagatgccgt tctagtaaaa aaagcattta
      841 gccgtatcaa acaacctctg acagaggttg agatttttca tactgatcgt ggaaaagagt
      901 ttgataacca agctattgat gaattattaa caacttttga catcaatcga tcattgagtc
      961 ataaaggctg tccttttgat aatgccgtag ctga
//
LOCUS       DAFBSV010000189          991 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.199, whole genome shotgun sequence.
ACCESSION   DAFBSV010000189 DAFBSV010000000
VERSION     DAFBSV010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..991
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.199"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(21..94)
                     /locus_tag="LLB18_002788"
     tRNA            complement(21..94)
                     /locus_tag="LLB18_002788"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58..60),aa:Ile,seq:cat)
     gene            complement(108..181)
                     /locus_tag="LLB18_002789"
     tRNA            complement(108..181)
                     /locus_tag="LLB18_002789"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(145..147),aa:Met,seq:cat)
     gene            complement(209..281)
                     /locus_tag="LLB18_002790"
     tRNA            complement(209..281)
                     /locus_tag="LLB18_002790"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(246..248),aa:Ala,seq:tgc)
     gene            complement(301..374)
                     /locus_tag="LLB18_002791"
     tRNA            complement(301..374)
                     /locus_tag="LLB18_002791"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(338..340),aa:Pro,seq:tgg)
     gene            complement(384..457)
                     /locus_tag="LLB18_002792"
     tRNA            complement(384..457)
                     /locus_tag="LLB18_002792"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(421..423),aa:Arg,seq:acg)
     gene            complement(468..553)
                     /locus_tag="LLB18_002793"
     tRNA            complement(468..553)
                     /locus_tag="LLB18_002793"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(517..519),aa:Leu,seq:taa)
     gene            complement(570..641)
                     /locus_tag="LLB18_002794"
     tRNA            complement(570..641)
                     /locus_tag="LLB18_002794"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(607..609),aa:Gly,seq:gcc)
     gene            complement(653..725)
                     /locus_tag="LLB18_002795"
     tRNA            complement(653..725)
                     /locus_tag="LLB18_002795"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(690..692),aa:Thr,seq:tgt)
     gene            complement(743..824)
                     /locus_tag="LLB18_002796"
     tRNA            complement(743..824)
                     /locus_tag="LLB18_002796"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(788..790),aa:Leu,seq:tag)
     gene            complement(832..904)
                     /locus_tag="LLB18_002797"
     tRNA            complement(832..904)
                     /locus_tag="LLB18_002797"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(869..871),aa:Lys,seq:ttt)
     gene            complement(908..980)
                     /locus_tag="LLB18_002798"
     tRNA            complement(908..980)
                     /locus_tag="LLB18_002798"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(945..947),aa:Val,seq:tac)
BASE COUNT          260 a          283 c          235 g          213 t
ORIGIN      
        1 tgaaacttac aacgccacaa tggaccttgt aggactcgaa cctacgaccg gacggttatg
       61 agccgtctgc tctaaccaac tgagctaaag gtccaggctc ttaaaaatcg cggcggaggg
      121 gatcgaaccc ccgacctccc gggtatgaac cggacgctct agccagctga gctacaccgc
      181 gaaaaagata ttcattattt aaatgaaatg gagcctagcg ggatcgaacc gctgacctcc
      241 tgcgtgcaaa gcaggcgctc tcccagctga gctaaggccc cgtgtttaaa tttataatta
      301 tcgggaagac aggattcgaa cctgcgaccc cttggtccca aaccaagtgc tctaccaagc
      361 tgagctactt cccgtttaat taacgcgccc aagaggagtc gaacccctaa ccttttgatc
      421 cgtagtcaaa cactctatcc agttgagcta tgggcgcata tttgaaatgc cgaggaccgg
      481 aatcgaaccg gtacggtgat cactcaccgc aggattttaa gtcctgtgcg tctgccagtt
      541 ccgccacccc ggcgcgattg ctttggcaaa gcggaaaacg gggttcgaac ccgcgacccc
      601 caccttggca aggtggtgct ctaccactga gctatttccg cgtgtttaaa gatgccggct
      661 aaaggacttg aaccctcgac cctctgatta caaatcagat gctctaccaa ctgagctaag
      721 ccggcatgta aaacttaaat tatgcgggtg aagggacttg aacccccacg ccgtaaggcg
      781 ctagatccta aatctagtgc gtctgccaat tccgccacac ccgcaaaaat atgagccgta
      841 cagggctcga acctgtgacc ctctgattaa aagtcagatg ctctaccaac tgagctaacg
      901 gctcatatgg aggttaacgg gatcgaaccg ctgaccctct gcttgtaagg cagatgctct
      961 cccagctgag ctaaacctcc atggataact t
//
LOCUS       DAFBSV010000190          943 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.200, whole genome shotgun sequence.
ACCESSION   DAFBSV010000190 DAFBSV010000000
VERSION     DAFBSV010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.200"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..258
                     /locus_tag="LLB18_002799"
     CDS             <1..258
                     /locus_tag="LLB18_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245735.1"
                     /translation="KGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            260..397
                     /locus_tag="LLB18_002800"
     CDS             260..397
                     /locus_tag="LLB18_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBK5245736.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITDEEADKIINKDKSA
                     S"
     gene            434..727
                     /locus_tag="LLB18_002801"
     CDS             434..727
                     /locus_tag="LLB18_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245737.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
     gene            724..>943
                     /locus_tag="LLB18_002802"
     CDS             724..>943
                     /locus_tag="LLB18_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBK5245738.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGN"
BASE COUNT          350 a          134 c          201 g          258 t
ORIGIN      
        1 aaagggaatg ctgttgatag cgtagatgaa ttggctaata ttaaggcatt atacgaaacg
       61 ctgaaggcag aaaatgatga attgaaacag ctaaattcta aagcaatgct aaacaatgta
      121 gcaatcaagc aagaaaatgt cttattgaaa gaaaagtcag aaagtttagc gcagttgaat
      181 tcaaaaacga tgcttgcttc tgtacaaaat accaaggaaa tcgaagaaat caaaaaacaa
      241 ttacaaggtg ggaagtaaca tgtattcata tgaagatatc aaactaatgt atgactgggg
      301 ctgtttcact aacgaacaag taatggtttt cgttccatta tgcattacag acgaagaagc
      361 agataaaatc attaataaag ataagagcgc atcttaattg atgcgttttt atttaaggta
      421 aaggagttgt cacatgatta atttagggga atggggaatg atagcaggat caataaccgc
      481 tatcgtttct ttgattttat tagtaattag accgattgct gcatctttct cgaaaattac
      541 tgagactctt tcaaaagtaa gccacaattt agatttgctg actaaagatt tagaatcgag
      601 caaatcagat cgattgatga ttcatgaaga actaaagaaa cacgatgaaa gattagatac
      661 acatacagaa aaattggtgg aacacacgca acaaatcaaa actttgttta gggagagaag
      721 aaaatgaata ataaaacgtt cgaagtacta aaatggttcg cactggtaat tattcccgca
      781 ctagctactt tcgtggggtt agttggtaaa gcgctcaatt ggcagtacac agatatctgt
      841 gttgtcatca ttactggttt tggcgcgttt ttagggagtg tgttgggtgt atcaaatcga
      901 acctacaaaa tgttctcggc tgaaagcgaa gaaggaggaa aca
//
LOCUS       DAFBSV010000191          852 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.201, whole genome shotgun sequence.
ACCESSION   DAFBSV010000191 DAFBSV010000000
VERSION     DAFBSV010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..852
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.201"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            21..>852
                     /locus_tag="LLB18_002803"
     CDS             21..>852
                     /locus_tag="LLB18_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBK5245739.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     V"
BASE COUNT          293 a          147 c          164 g          248 t
ORIGIN      
        1 attataagga gtgagtacaa atgacctata cccatcttac aacggatgaa cttgtaataa
       61 tagagtctta tttcaaaatg aatcaatctg ttgctaaaac tgcccattgc ttgaatcgtt
      121 caagacaaac gatccataaa gtatatctgt tcttcaagca aggaaaatca gccttagaat
      181 attatcaaca gtataagaaa aacaaatcaa actgtggtag acgtccgctt gttttacccg
      241 aggaacaatc agaatatatt caaagaaagg ttgttcaagg atggacaccc gatgtgattg
      301 ttggtcgtgc agcgtttcct attagttgtt ctgctcgtac catttatcgt atgttcaaaa
      361 aggggctatt tgattcttct gacttaccga tgaaaggcaa gcgtaaaccg aatggacatc
      421 aagaaagacg tggaaaacaa actttccgcc gctctattca tgaacgtgaa aaggattata
      481 gccaattctc aaatgagttt ggtcaccttg aaggtgacac tatcgtaggt ctgaaacata
      541 aaagtgctgt aattacctta gttgaacgat tatcaaaagt tatcatcaca ttgaaaccgt
      601 gtggtagaca agcgattgat attgaaaaaa aattaaatca atggtttgaa tctgtaccga
      661 aaaacctatt caaatccatc acttttgatt gtggaaagga attttcaaat tggaaacaga
      721 tcagtaatgt caatgatatt gccatttatt tcgctgatcc aggaacgccg tctcaaagag
      781 gcctaaacga gaattctaac ggattgttac gtagagatgg tttattgaaa tctatggatt
      841 tcaattcagt ag
//
LOCUS       DAFBSV010000192          816 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.202, whole genome shotgun sequence.
ACCESSION   DAFBSV010000192 DAFBSV010000000
VERSION     DAFBSV010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..816
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.202"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(257..517)
                     /locus_tag="LLB18_002804"
     CDS             complement(257..517)
                     /locus_tag="LLB18_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245740.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          329 a          123 c           97 g          267 t
ORIGIN      
        1 atcttattgt agaaaaagaa aaaccgcgaa gcaaccacct gcctaggatt aatggttact
       61 tacacggttt atattacact ctcatcatta aaaaagtatc tttcgatatt actaaacaat
      121 gaaattatct atttgaaatt taaatctgat aatatattga gtgttccaat gagggctttg
      181 atcctattat ccatatcttt ttcagtttta atattgatac acattataag aaaaagaaac
      241 ttttggttaa tttatttcat cccagtgcaa aatataaaaa agtaaaatag accataggca
      301 atagattaac aattaatata atacaagcaa atattctatt cattgtattt ctgctttcaa
      361 aaagttctaa tattgaaagt ataattccac aaatgcctat aataagtatg ggaataagat
      421 tagaaaataa caccccgagc caatctgtga aaattactat atttactaat atccctatta
      481 acatacctat catatttatt aaatcaattt ttttcattag atatttctcc tttattaaat
      541 ctgaagtact tatattaaaa taattctaaa ctatttacct caaaaagtgc aataaattat
      601 ttctgaacaa taaaatgata gtcaaaacaa aaaaatattg ttaatcgttc agagccatcc
      661 gagagtgtaa aatattttgt gtaaatgaaa aaatccatac aaaaaaggaa ggcgcttctg
      721 tagaataaag ttaacgacaa ccaattcaca gaaaagagga cttccctatg aatgatttta
      781 ctacagaaat tgtgcaaact ctagtcacta aaggcg
//
LOCUS       DAFBSV010000193          791 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.203, whole genome shotgun sequence.
ACCESSION   DAFBSV010000193 DAFBSV010000000
VERSION     DAFBSV010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.203"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..782
                     /locus_tag="LLB18_002805"
     CDS             <1..782
                     /locus_tag="LLB18_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBK5245741.1"
                     /translation="DMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNG
                     VSLARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGE
                     LISLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKL
                     IKNNKDKYIFISKNGNPISIQAYNQSLRAVSKELNIDKKVSSHMLRHSHISLLTELGI
                     PLKAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
BASE COUNT          340 a          107 c          102 g          242 t
ORIGIN      
        1 aagatatgct agattactac tattttgaaa aaaatttatc atataattat gtaatacatt
       61 taaaaacttt tacaggaatg atttttaaat tcgccaaccg tcgatatgga ttaaaatata
      121 atcccgtaaa tggggtttct ttagcaagaa aacctaagac aaacgaagaa ataaaaaaag
      181 aaaaagatgg ttatttatca aaagaagaag ttcaaatgat tgctagtaaa caaaaaagtt
      241 cacatcaaca gtcacgttat tctttaatta ctaaattttt gtttttaact ggactacgtt
      301 atggtgaatt gatatctttg actgaatctg attatgatgg taataaaatt acggtttctg
      361 gtacttatga ttacgagtta aaaattaaaa caacaactaa aaatacaggt tcttatagaa
      421 ccattgaatt atcaagtaat gctaaagaaa tcatagatca attaattgaa gaaaacaaat
      481 taattaagaa taataaagat aaatacattt tcatctctaa aaatggtaac ccgatatcta
      541 ttcaagcata taatcaatct ttaagagcag tatccaaaga attaaacata gataaaaaag
      601 tttcttctca catgttaagg cattcccaca tttctctact tacagaatta ggaatcccat
      661 taaaagccat tatggatcgt gtaggacatg aagattcaaa aacaacatta aagatttata
      721 ctcatacaac taaaaatatg caaaatcaac tagtagaaaa actaggaaaa atagaaattt
      781 aaattgcccc t
//
LOCUS       DAFBSV010000194          763 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.204, whole genome shotgun sequence.
ACCESSION   DAFBSV010000194 DAFBSV010000000
VERSION     DAFBSV010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..763
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.204"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(237..716)
                     /locus_tag="LLB18_002806"
     CDS             complement(237..716)
                     /locus_tag="LLB18_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245742.1"
                     /translation="MCYFDREQDFFYYGGMGGGSIVPKINLVELDVNNYRELYVFNSL
                     DFEIPMKQMKNIDIHILPSESCQIEYSIEYFYKGKKIKKCDKCFESAVVKFPQFKLNP
                     AASIQFQGHVFDVLAKDNIKKYKKGNIFHIDIQISSNLEDIKKAFKIKTIGTAPNFK"
BASE COUNT          261 a          101 c           85 g          316 t
ORIGIN      
        1 aacaataaat gaagactttt ttattgttaa ttgtttattt ttctattatt agatatgaaa
       61 atcgcattta gataaaatag aaaaatatga atatatttta aatattaaga tgagagtcat
      121 taacttatga tagtagtcaa tttgcttttc actaattaca aaatatgtga tataggaagt
      181 ttagttattg ttctcataat gccatcctgt ttttagatta tctagtaatt tttttgttat
      241 ttaaaattag gagcagtgcc aattgtttta attttaaagg ctttttttat atcttctaaa
      301 ttagaagata tttgtatatc aatatggaat atattacctt ttttgtattt ttttatgtta
      361 tctttagcta aaacatcaaa tacatgtcct tgaaattgta tcgaggcagc tggatttagt
      421 ttaaattgag gaaactttac cacagctgat tcaaaacact tgtcacattt ttttattttt
      481 ttacctttgt aaaaatattc gattgaatat tctatttggc acgactcact tggcagtata
      541 tgtatgtcaa tatttttcat ctgtttcata ggtatttcaa aatctaaact attaaaaaca
      601 tataattccc tgtaattatt tacatctaac tctactaaat ttatctttgg aacaatagat
      661 cctccaccca ttccaccata ataaaaaaaa tcttgttctc tatcaaaata gcacatatta
      721 agctcagttt gtttatcatc ctcaataatt ttataaatca aac
//
LOCUS       DAFBSV010000195          755 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.205, whole genome shotgun sequence.
ACCESSION   DAFBSV010000195 DAFBSV010000000
VERSION     DAFBSV010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..755
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.205"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..>755
                     /locus_tag="LLB18_002807"
     CDS             <1..>755
                     /locus_tag="LLB18_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HBK5245743.1"
                     /translation="IIACVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSS
                     NLAYTIKIIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKK
                     SYFYGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHKIH
                     EKLALKGITISVPPRKNMDKSEKLDHSLLGKQRKTVETVFSSLEKLGCQNFNSRSVKG
                     LESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT          253 a          134 c          137 g          231 t
ORIGIN      
        1 tgattattgc ttgtgttata tggggcataa ttaatggcta tactagccaa agagccacgt
       61 atagagcggt ttgttccgtc ttatttccta atggtgactt tcctagtagg agtcgattca
      121 ctcgcttaag ttcaaactta gcttacacta tcaagattat tcgatacttt ttcatcaaga
      181 agctcaccaa aggtgaacta gtcggaatta tagatagttt tcctagtcca ttatgtaaac
      241 cagttagaaa tagacaagca aaactattga atcaaatagc caaagttggc tataactcaa
      301 caaaaaaatc ttatttttat ggtcttaaaa ttcatatgat cgttactaag actggctttc
      361 cgattactta ctcaatcacg aatccaggtg tccatgacgt gaaagtgtta gagactttat
      421 cggaagaagc gaatcttccc aatatcctag gggacaaagg atatattagc cataaaatcc
      481 atgaaaagct tgcccttaag ggcattacta tatccgttcc gccacgtaaa aacatggata
      541 aatcagaaaa actagaccac agcttacttg gaaaacaaag aaaaacagtt gagactgttt
      601 tttcttcctt agaaaaatta ggttgtcaaa atttcaactc acgttctgtt aaagggctag
      661 agagtagatt tgaaagcata ttactggctt acagtgttct attaagtcga gcacaacgac
      721 gttttgaagg aactttgaga tattctttag gatat
//
LOCUS       DAFBSV010000196          751 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.206, whole genome shotgun sequence.
ACCESSION   DAFBSV010000196 DAFBSV010000000
VERSION     DAFBSV010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..751
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.206"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(<1..>751)
                     /locus_tag="LLB18_002808"
     rRNA            complement(<1..>751)
                     /locus_tag="LLB18_002808"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          148 a          245 c          165 g          193 t
ORIGIN      
        1 atgctccacc gcttgtgcgg gcccccgtca attcctttga gtttcaacct tgcggtcgta
       61 ctccccaggc ggagtgctta atgcgttagc tgcagcactg aagggcggaa accctccaac
      121 acttagcact catcgtttac ggcgtggact accagggtat ctaatcctgt ttgctcccca
      181 cgctttcgag cctcagcgtc agttacagac cagagagccg ccttcgccac tggtgttcct
      241 ccatatatct acgcatttca ccgctacaca tggaattcca ctctcctctt ctgcactcaa
      301 gtctcccagt ttccaatgac cctccccggt tgagccgggg gctttcacat cagacttaag
      361 aaaccgcctg cgctcgcttt acgcccaata aatccggaca acgcttgcca cctacgtatt
      421 accgcggctg ctggcacgta gttagccgtg gctttctggt tagataccgt caagggatga
      481 acagttactc tcatccttgt tcttctctaa caacagagtt ttacgatccg aaaaccttct
      541 tcactcacgc ggcgttgctc ggtcagactt tcgtccattg ccgaagattc cctactgctg
      601 cctcccgtag gagtttgggc cgtgtctcag tcccaatgtg gccgatcacc ctctcaggtc
      661 ggctatgcat cgtggccttg gtgagccgtt acctcaccaa ctagctaatg caccgcgggt
      721 ccatccatca gcgacacccg aaagcgcctt t
//
LOCUS       DAFBSV010000197          720 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.207, whole genome shotgun sequence.
ACCESSION   DAFBSV010000197 DAFBSV010000000
VERSION     DAFBSV010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.207"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            312..608
                     /locus_tag="LLB18_002809"
     CDS             312..608
                     /locus_tag="LLB18_002809"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBK5245744.1"
                     /translation="MSAVVTDLTYVRVGTNWAYICLMIDLFNREIIGHSCGNKKDAQL
                     VKRAIQSIPYSLQEIELFHTDRGKEFDNQTIQNLMNGLVIKFLSTVCMKKLDVC"
     gene            complement(531..720)
                     /locus_tag="LLB18_002810"
                     /pseudo
     CDS             complement(531..720)
                     /locus_tag="LLB18_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          246 a          134 c          105 g          235 t
ORIGIN      
        1 ttttacactc tctattattc ttttcataaa tattgtaaat agaagtatta aaaatatata
       61 caaaaagtat tatttcgaga aagataaata ttttcaaaaa ccttttcata atcctcaccc
      121 tttcttacac tgataaatca tgcgtctaat attcaaatta tactcgatat gctttagcta
      181 atcagccaac tctgtttgtc tactatcatt atatcaatag acaatatctg ctcccgtctt
      241 tatgatcgtg ccaaagcaat caaaagaaaa ttgcgaatca cttagatcga aagtttactc
      301 aaacaaaagc attgtcagcg gttgtcacgg atttaactta tgttcgggtc gggacaaatt
      361 gggcttatat ttgtttgatg attgatttat tcaatcgtga aattattggc cattcttgcg
      421 gaaataaaaa agatgcgcag cttgtaaaaa gggccattca aagcattcct tactcacttc
      481 aagaaatcga actcttccat acggatcgtg gaaaagaatt tgataaccaa accattcaga
      541 atctcatgaa tggtttggtt atcaaattcc tttccacggt ctgtatgaaa aagcttgacg
      601 tctgttaaag aatacggtat ccgtccaaag gcttctttta ccaatgaggc atctttcttc
      661 tcaccacagg aataaccaat aatttctcga ttaaacaaat caagtattaa gcagatataa
//
LOCUS       DAFBSV010000198          679 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.208, whole genome shotgun sequence.
ACCESSION   DAFBSV010000198 DAFBSV010000000
VERSION     DAFBSV010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..679
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.208"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
BASE COUNT          240 a          114 c           80 g          245 t
ORIGIN      
        1 ccaaattact tcatcaaaac attgatataa tttttattat atcagtattt attcttgata
       61 cataaatgag aaaataaata ctttaaatct attgactaca agtagtcatt aagtcttcat
      121 aagatgtaca atatgacatt aaaaaaataa aagcttacga ccatccgtta aatctgacac
      181 taaataatgg actgctttct tttgtattag caggttacgt tgactatgaa tattcaccag
      241 attatttgga gaaacctctt caacacgaga acaatgatat taattttaga tttgtctacg
      301 agtcaaaaag taaaacatgg ttagttgatc aattaagcac gataaacaca agcttccatg
      361 aattacctaa acctgaaaat gaagttgaga tggtcattaa aatcttctaa aaaagaagcg
      421 ttgaagggga aatattcctt tcaacgctct tttttatatg cttagaaaca taaataaatt
      481 gtatactttc tttttagccc ctattacttt tcacgaaaaa tatctttttt tcgacgctag
      541 cgtttctcta cttctaatac tgtacacagt ttttgtatta ttgaaaaatt actcattatt
      601 tagcattaat ccacatcgtt ttatcaatcg accttcatac taaactactt taaagtcatc
      661 ttccttctcg tttttcatt
//
LOCUS       DAFBSV010000199          628 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.209, whole genome shotgun sequence.
ACCESSION   DAFBSV010000199 DAFBSV010000000
VERSION     DAFBSV010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..628
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.209"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
BASE COUNT          241 a           80 c           79 g          228 t
ORIGIN      
        1 aagaaggtat caagagtcac agtgaattta ttccgaaaag tgaaaagagc aaatataaaa
       61 tttaataaaa atatagaact aaataggaaa acgtagacgt aattttctac gttttccttt
      121 tcatatatat taaatattac ggaaaattat ataaactaat ttagtgtttt gtttgtaatt
      181 cctaattttg ctccactttt agataatttt taggtctatt taactcatca gacattctat
      241 gctcattttc tccaaatttg tttcaactct ttcgtactta attttgcgta tttgaaaatt
      301 cttcttttag agtactttta ttacgatact agtatgatat atatctatag caaacagtta
      361 aaatcttcct aaaataagcg aatagcattc ctaaaaccta taaaattttt agatgaagcg
      421 acaagtggac aattaataaa ctacttgaac atgaaattat ggatcacctt tcaaatttag
      481 aaaatggaat tcttatactt attgcacaac atttattgat tgcaaaatta tgtgacaaaa
      541 agaactagta gaagaaggaa taatggcttg ataataaagt actacctatt aaaggtagta
      601 ctttatttaa tttagtataa attaacat
//
LOCUS       DAFBSV010000200          616 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.210, whole genome shotgun sequence.
ACCESSION   DAFBSV010000200 DAFBSV010000000
VERSION     DAFBSV010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..616
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.210"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(58..489)
                     /locus_tag="LLB18_002811"
     CDS             complement(58..489)
                     /locus_tag="LLB18_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HBK5245745.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          213 a           81 c           68 g          254 t
ORIGIN      
        1 tcttttctta attgtacaat tagtattatc tgcactactt tctaattaaa taaattttta
       61 gttattaact tgattaaaat cagagataat atcatttaat tcagtttgaa gggttgtaac
      121 gattaaatgg aaattttctt catctgtttt attatatggg gatgttttcg ttatatataa
      181 caacttttct ttttcaattt tcattaataa ctctgtcgaa gtctgtactt tatcttgata
      241 attaaatgca gacataccac tttgtataat tgtaattatt gctgaagcaa ttgaaacaat
      301 caatagtaaa gacctgtgtt cggaagcctg atcaattaat attgggatac tagctgataa
      361 gactattttt ataatatttc cgataccaat tactctatta taaaatcgaa tttctttttt
      421 taatctatcg attgtagaat caatagattc gataaacgct ttttgatcca tcattttctc
      481 tccaatcatt ttattaaaat cattaacaaa aatattataa taggatttaa gtaagttcta
      541 actaatcaca tataaaaata aaaaaacatt tgtattttat caaagtttta ttatacttgt
      601 caatttgtgt acatcc
//
LOCUS       DAFBSV010000201          593 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.211, whole genome shotgun sequence.
ACCESSION   DAFBSV010000201 DAFBSV010000000
VERSION     DAFBSV010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..593
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.211"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(318..581)
                     /locus_tag="LLB18_002812"
     CDS             complement(318..581)
                     /locus_tag="LLB18_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HBK5245746.1"
                     /translation="MKKNLLLVLPILGFAGFFVGVPMLSANIGISSYAAKKVIDIINT
                     GSTVATIISIVAAVVGGGLITAGIVATAKSLIKKYGAKYAAAW"
BASE COUNT          224 a          104 c           79 g          186 t
ORIGIN      
        1 gccttccttt tttgtatgga ttttttcatt tacacaaaat attttatact ctcctgaatt
       61 ttttcatgtt gaaaacatca ctaatcaaag gcaaattata atttagaaat agaatgaaaa
      121 cactaaatga aaatagaaca ttagaaaaaa tagaatcaaa aaaacccaag actagtgccg
      181 aaataaggga aacaatcgaa gctacaaaaa ataatgattt cgttgaacag gaccaattta
      241 tttgtttccg atatttctca aaaagaactt tctttgggaa agttaaaggc gactgtaaag
      301 tcgcctttag tcctttttta ccaagctgct gcatatttag ctccatattt tttaattaat
      361 gatttggctg tagcaacaat accagctgta attaatccgc ctccaacaac tgcagcaaca
      421 atagaaatga ttgtagcaac cgtgctacca gtattaatta tgtcaataac ttttttagct
      481 gcataagaag aaattccaat gttagcactt agcattggta caccaacaaa gaatcccgca
      541 aaacctaaaa ttggtaaaac taataataaa ttctttttca taataattcc tct
//
LOCUS       DAFBSV010000202          584 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.212, whole genome shotgun sequence.
ACCESSION   DAFBSV010000202 DAFBSV010000000
VERSION     DAFBSV010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..584
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.212"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..300
                     /locus_tag="LLB18_002813"
     CDS             <1..300
                     /locus_tag="LLB18_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK5245747.1"
                     /translation="FMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEG
                     FNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
BASE COUNT          210 a          101 c           69 g          204 t
ORIGIN      
        1 tttatgacta ggaaatggaa aaagcagtat ccaagagtcg tcaatttact cttgaatcct
       61 gccctattaa ccttttataa tttccctcac gccatcagac gaacaattta ttcgacgaac
      121 ctgattgaag gctttaataa gcagctaaaa cgatatactc gaagaaaaga acaattccct
      181 aatgaagaat ctctagagag attcttcatt tctcaattta atcaatataa ccaaaaattt
      241 ttaggtagaa ttcacaaggg atttaaagaa attcaggata cattagagtc gatgatttaa
      301 ctgtaattaa cagaatggat tttccattta catataattc ttgacgctac cataatctaa
      361 ataaccatca tattcatcta ctacttatat aattgagttt tattaaactt tttaagtttc
      421 tattctatca aatatttaaa caatctctgc atccgaaaag actacctcgt atagttttac
      481 taacaatatt tttattagcg tgttcaaatc ctgatttctt gtatcaatta ttttctgttc
      541 actttcaata agaaaaaagt ctttacttcc atggataata ataa
//
LOCUS       DAFBSV010000203          578 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.213, whole genome shotgun sequence.
ACCESSION   DAFBSV010000203 DAFBSV010000000
VERSION     DAFBSV010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..578
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.213"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            126..413
                     /locus_tag="LLB18_002814"
                     /pseudo
     CDS             126..413
                     /locus_tag="LLB18_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            427..>578
                     /locus_tag="LLB18_002815"
     CDS             427..>578
                     /locus_tag="LLB18_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245748.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWV"
BASE COUNT          200 a           91 c          122 g          165 t
ORIGIN      
        1 cattggtgca gacagatgga gaccaagcca ttgcaggaca taagaatttt tcaggttctg
       61 taacaatcaa taataaacgt gttttgacga ctgatgataa cagatatgaa gtggtaaatc
      121 tggttgtcac taacggtaat acagggacag caaagcttta tcgtgaagga aaaacagttt
      181 ctatatattt tgtggcttta aacggaaaaa gtagtggcgg gaatgattcg gttattttaa
      241 ctgttccaga aggctatcgg acaccaatta gttttgaaca actggttggg tcaatagacc
      301 gttctacttt gaacagtgct caactatcta ttggcgcaga cggagccatt aaatggagaa
      361 gaaattcaag ttatggatca gcttattcat ttgttatcac ttattcaatt taagggagga
      421 aatctaatga aagtagttta caaatcaatc aagccttacg gattcgagca aatcattttg
      481 aacaatcaag aaaatatccc tgaaaactgt acagagatta aaccaccagt tcctaactgg
      541 agaccaagat ttgattttga taaaaaacag tgggttga
//
LOCUS       DAFBSV010000204          577 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.214, whole genome shotgun sequence.
ACCESSION   DAFBSV010000204 DAFBSV010000000
VERSION     DAFBSV010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..577
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.214"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            141..398
                     /locus_tag="LLB18_002816"
     CDS             141..398
                     /locus_tag="LLB18_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245749.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
BASE COUNT          240 a           71 c           80 g          186 t
ORIGIN      
        1 ttctgtccac gttcatttta ctccaaagtt ttcctcattt caaaagaaaa tcacagaata
       61 cacgaagaag cgtttctatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaatt tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaagaacttg
      361 ataaagaatt taaagaaatc aatgacttat tactataatt gatttatacg actcattttt
      421 gagtcgtcag actgcaaaca acactctaaa tttaggagtt tgtctacagt ctgaataaat
      481 tttaaattta ttgtccataa tgttattatg aatttatagc attaagaaaa gagataagac
      541 tttacatttt tttaggaatg taaagtctta tctcttt
//
LOCUS       DAFBSV010000205          509 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.215, whole genome shotgun sequence.
ACCESSION   DAFBSV010000205 DAFBSV010000000
VERSION     DAFBSV010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.215"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(<1..132)
                     /locus_tag="LLB18_002817"
     CDS             complement(<1..132)
                     /locus_tag="LLB18_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBK5245750.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          183 a           93 c           91 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactatta
//
LOCUS       DAFBSV010000206          483 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.216, whole genome shotgun sequence.
ACCESSION   DAFBSV010000206 DAFBSV010000000
VERSION     DAFBSV010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.216"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(<1..408)
                     /locus_tag="LLB18_002818"
     CDS             complement(<1..408)
                     /locus_tag="LLB18_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245751.1"
                     /translation="MGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEINRKIYWVS
                     IPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELIFSLTTPGN
                     ALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKP"
BASE COUNT          180 a           78 c           62 g          163 t
ORIGIN      
        1 cggctttcca aatgatgaaa tacctaaatc taacttatta agaaagttga aatttttata
       61 ttcaggaaac catttattaa tttcatgtgc agcacgtaat gcattccctg gagttgtcaa
      121 agagaaaatt aattctgcta agcttattat tgaaaatact gataacttat aattatatcg
      181 tccattgaca atcaaatata aactaactat acttgttaga acaaaaaaac aggcgttgac
      241 ttgttcttga ttagttaaaa atatcaataa aggaatactt acccaatata tttttctatt
      301 tatttcttct cctcttaaga gttgaaaaaa cggataaaaa gttagtaaac taaatgctac
      361 tggccactga tagttcaagg tggttgctct ccaaccggtt tcccccatta ctgtcaatgg
      421 tattaaacag tatatagagc aaaccaataa taaattttta acatttattt tctcaaaaac
      481 ata
//
LOCUS       DAFBSV010000207          460 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.217, whole genome shotgun sequence.
ACCESSION   DAFBSV010000207 DAFBSV010000000
VERSION     DAFBSV010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.217"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(20..91)
                     /locus_tag="LLB18_002819"
     tRNA            complement(20..91)
                     /locus_tag="LLB18_002819"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56..58),aa:Glu,seq:ttc)
     gene            complement(113..200)
                     /locus_tag="LLB18_002820"
     tRNA            complement(113..200)
                     /locus_tag="LLB18_002820"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(164..166),aa:Ser,seq:gct)
     gene            complement(225..298)
                     /locus_tag="LLB18_002821"
     tRNA            complement(225..298)
                     /locus_tag="LLB18_002821"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(262..264),aa:Ile,seq:gat)
     gene            complement(312..382)
                     /locus_tag="LLB18_002822"
     tRNA            complement(312..382)
                     /locus_tag="LLB18_002822"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(348..350),aa:Gly,seq:tcc)
     gene            complement(384..459)
                     /locus_tag="LLB18_002823"
     tRNA            complement(384..459)
                     /locus_tag="LLB18_002823"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(424..426),aa:Asp,seq:gtc)
BASE COUNT          132 a          128 c          108 g           92 t
ORIGIN      
        1 taaaactata ttaaattaat gacccgtacg ggattcgaac ccgtgttacc gccgtgaaag
       61 ggcggtgtct taaccgcttg accaacgggc caggtaaaac aaaatattga aacggagaag
      121 gagggatttg aaccctcgcg ccggtttccc gacctacacc cttagcaggg gcgcctcttc
      181 agccacttga gtacttcccc aaaaccaata agattttgta ctaatgggcc taaatggact
      241 cgaaccatcg acctcacgct tatcaggcgt gcgctctaac cagctgagct ataggcccat
      301 aaaaaactaa aagcgggtga cgagaatcga actcgcgaca acagcttgga aggctgtggt
      361 tttaccacta aactacaccc gcatggcggt tccgacggga atcgaacccg cgatctcctg
      421 cgtgacaggc aggcatgtta acccctacac cacggaacca
//
LOCUS       DAFBSV010000208          449 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.218, whole genome shotgun sequence.
ACCESSION   DAFBSV010000208 DAFBSV010000000
VERSION     DAFBSV010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.218"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
BASE COUNT          142 a           90 c           68 g          149 t
ORIGIN      
        1 gacactcctc ttaatataca gtcctattgt ataaagtgtt actatataca tagtaactgt
       61 atacataaaa aaagtcaagt attagaaaaa agttcaaaag atcaagtgtg cgcttcgctc
      121 ccactcccct cgacgtttta gtagcctttc cctcacttcg ttcagtccaa gccaactaaa
      181 aagttttcgg gatacattct ccttctcttc ctaataatca attaaaattt taatctttat
      241 atttctgcta atcactcagg aaacagtaca gaaaaacaaa cacgtatcat agatataaat
      301 gtaatggcat agtgcgggtt ttattttcag cctgtatcat agctaaacaa atcgagttgt
      361 gtgtccgttt ttgggcgttc tgctagcttg tttaaagtct cttgaatgaa tgtatgttct
      421 aagtcaaaaa actctgacag cgcctttat
//
LOCUS       DAFBSV010000209          432 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.denovo.219, whole genome shotgun sequence.
ACCESSION   DAFBSV010000209 DAFBSV010000000
VERSION     DAFBSV010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.denovo.219"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(58..142)
                     /locus_tag="LLB18_002824"
     tRNA            complement(58..142)
                     /locus_tag="LLB18_002824"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(106..108),aa:Leu,seq:caa)
     gene            complement(163..233)
                     /locus_tag="LLB18_002825"
     tRNA            complement(163..233)
                     /locus_tag="LLB18_002825"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(199..201),aa:Cys,seq:gca)
     gene            complement(279..350)
                     /locus_tag="LLB18_002826"
     tRNA            complement(279..350)
                     /locus_tag="LLB18_002826"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(316..318),aa:Gln,seq:ttg)
BASE COUNT          126 a          101 c           97 g          108 t
ORIGIN      
        1 ataaaagatg ttatttaatt tctcaataaa aaactaagat gaagacatct tagtcaatac
       61 cggcggccgg ggtcgaaccg gcacgccctc aacgggcact ggattttgag tccagcgcgt
      121 ctgccaattc cgccacgccg gcaagttgat ttattagtac taaggcggta accggatttg
      181 aaccggtgat gaaggttttg cagacctctg ccttaccact tggctatacc gccattatac
      241 tattatcaat ctataaaata aagaataaat tatagaaact ggggtagctg gattcgaacc
      301 aacgcatgag ggagtcaaag tcccttgcct taccgcttgg ctatacccca atgaaatgga
      361 ggagagtgga ttcgaaccac tgaaccctaa ggaacggatt tacagtccgt cgcgtttagc
      421 cacttcgcta ct
//
LOCUS       DAFBSV010000210        30793 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.guided.023, whole genome shotgun sequence.
ACCESSION   DAFBSV010000210 DAFBSV010000000
VERSION     DAFBSV010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30793
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.guided.023"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..1226
                     /locus_tag="LLB18_002827"
     CDS             <1..1226
                     /locus_tag="LLB18_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBK5245752.1"
                     /translation="TVNSNVARNIASNIRAIYVDEFQDTRELQYNVIAKLLQNNPQIQ
                     SMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCYRSNQRLVDFYSNFQSC
                     PYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIESGIHEKDICVLAPQHYP
                     LFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFTESGEKVRRRKLIANDI
                     LIILKNEFGIEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLYKFVTKHIFVNLNIDEK
                     NYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGITLTTAHKVKGNEYDTV
                     IAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNLFLFSEVGYFTSKGDLL
                     YPTQLLDKIEFDYNI"
     gene            1426..1740
                     /locus_tag="LLB18_002828"
     CDS             1426..1740
                     /locus_tag="LLB18_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBK5245753.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            1761..2138
                     /locus_tag="LLB18_002829"
     CDS             1761..2138
                     /locus_tag="LLB18_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBK5245754.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            2148..2921
                     /locus_tag="LLB18_002830"
     CDS             2148..2921
                     /locus_tag="LLB18_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245755.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            2943..4346
                     /locus_tag="LLB18_002831"
     CDS             2943..4346
                     /locus_tag="LLB18_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBK5245756.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            4528..5712
                     /locus_tag="LLB18_002832"
     CDS             4528..5712
                     /locus_tag="LLB18_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBK5245757.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            5709..5999
                     /locus_tag="LLB18_002833"
     CDS             5709..5999
                     /locus_tag="LLB18_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245758.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            5996..6217
                     /locus_tag="LLB18_002834"
     CDS             5996..6217
                     /locus_tag="LLB18_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245759.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            6259..7038
                     /locus_tag="LLB18_002835"
     CDS             6259..7038
                     /locus_tag="LLB18_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HBK5245760.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            7105..7599
                     /locus_tag="LLB18_002836"
     CDS             7105..7599
                     /locus_tag="LLB18_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBK5245761.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            7655..8293
                     /locus_tag="LLB18_002837"
     CDS             7655..8293
                     /locus_tag="LLB18_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245762.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            8365..8760
                     /locus_tag="LLB18_002838"
     CDS             8365..8760
                     /locus_tag="LLB18_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK5245763.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            8744..11197
                     /locus_tag="LLB18_002839"
     CDS             8744..11197
                     /locus_tag="LLB18_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK5245764.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            11194..13221
                     /locus_tag="LLB18_002840"
     CDS             11194..13221
                     /locus_tag="LLB18_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5245765.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            13218..14240
                     /locus_tag="LLB18_002841"
     CDS             13218..14240
                     /locus_tag="LLB18_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBK5245766.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDGETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            14257..15186
                     /locus_tag="LLB18_002842"
     CDS             14257..15186
                     /locus_tag="LLB18_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK5245767.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            15438..17357
                     /gene="tet(M)"
                     /locus_tag="LLB18_002843"
     CDS             15438..17357
                     /gene="tet(M)"
                     /locus_tag="LLB18_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HBK5245768.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIV
                     NTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRL
                     NSRIDKVRYMFNKIT"
     gene            17455..17643
                     /locus_tag="LLB18_002844"
     CDS             17455..17643
                     /locus_tag="LLB18_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBK5245769.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(17701..18054)
                     /locus_tag="LLB18_002845"
     CDS             complement(17701..18054)
                     /locus_tag="LLB18_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5245770.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            18585..19007
                     /locus_tag="LLB18_002846"
     CDS             18585..19007
                     /locus_tag="LLB18_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK5245771.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            19004..19234
                     /locus_tag="LLB18_002847"
     CDS             19004..19234
                     /locus_tag="LLB18_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5245772.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            19732..19932
                     /locus_tag="LLB18_002848"
     CDS             19732..19932
                     /locus_tag="LLB18_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBK5245773.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            19959..21152
                     /locus_tag="LLB18_002849"
     CDS             19959..21152
                     /locus_tag="LLB18_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBK5245774.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(21220..22785)
                     /gene="guaA"
                     /locus_tag="LLB18_002850"
     CDS             complement(21220..22785)
                     /gene="guaA"
                     /locus_tag="LLB18_002850"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBK5245775.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(22844..23767)
                     /locus_tag="LLB18_002851"
     CDS             complement(22844..23767)
                     /locus_tag="LLB18_002851"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HBK5245776.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            23963..24568
                     /locus_tag="LLB18_002852"
     CDS             23963..24568
                     /locus_tag="LLB18_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBK5245777.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            24876..25892
                     /locus_tag="LLB18_002853"
     CDS             24876..25892
                     /locus_tag="LLB18_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBK5245778.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            26033..27334
                     /locus_tag="LLB18_002854"
     CDS             26033..27334
                     /locus_tag="LLB18_002854"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBK5245779.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            27380..28042
                     /gene="deoC"
                     /locus_tag="LLB18_002855"
     CDS             27380..28042
                     /gene="deoC"
                     /locus_tag="LLB18_002855"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBK5245780.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            28063..28461
                     /locus_tag="LLB18_002856"
     CDS             28063..28461
                     /locus_tag="LLB18_002856"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBK5245781.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            28527..29609
                     /locus_tag="LLB18_002857"
     CDS             28527..29609
                     /locus_tag="LLB18_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK5245782.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            29821..>30793
                     /locus_tag="LLB18_002858"
     CDS             29821..>30793
                     /locus_tag="LLB18_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5245783.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDI"
BASE COUNT        10373 a         5277 c         6228 g         8915 t
ORIGIN      
        1 taactgtaaa cagtaacgtt gcacgtaata ttgctagtaa tataagggcg atttatgtgg
       61 atgaatttca agatactaga gaattacaat acaatgtaat agctaaatta cttcaaaaca
      121 accctcaaat tcagtcaatg tttgttggag atattgacca agcaatttat ggatcattag
      181 atggtatagc taaatcagtt gaagaactag aaatgctaac tagtcacact tttcaatcaa
      241 agacgctaca tggctgttac aggtctaatc agagattagt agacttctac tctaattttc
      301 agagttgtcc ttacgagatt gaaagcagag ggaataataa aaacgaccgt ggttttataa
      361 gttatgattg caaagttact aaggaggatt tacccaacat aataaaaaat ataataaagg
      421 aaaagattga aagcggcatt catgaaaaag atatttgtgt acttgctcct caacactatc
      481 ctctgttttc actgggtgag tatttaaaga aagaattacc gtattgcaat tttgatgcta
      541 taaatatatc accaattaag gtaaataatc atagtttatt tttcaagtta gcaattttgt
      601 actttactga atcaggtgaa aaggttcgaa gaagaaagct aattgcaaac gatattttaa
      661 ttatattaaa aaatgaattt ggaatagaag ttaaagatta ttttattgac ttagatttat
      721 tacagctaat aaacagtgtg aaaagaatgt atagtggaga cgacaacggt gttgatttat
      781 acaaatttgt taccaaacat atatttgtta atcttaatat tgacgagaaa aattacccgt
      841 ctatttttaa gcactatcta ttttttatta acgaagtaga agatcggata aaaaataatt
      901 cattatctag tagtgtatct agttttaaga agatgtttaa atctcgagat ggtatcacac
      961 ttactacagc acataaagtt aaaggaaatg agtatgatac tgttatcgct attaatcttc
     1021 taaacgggaa aattcctcat tggaatgaaa tttttaatgt ttctgataaa ggaattagtt
     1081 cagcgagaaa actactatac gtaatttgtt caagagcaaa aaataattta tttcttttct
     1141 cagaggtggg ttattttacg agtaaaggag acttgcttta tcccactcaa ttattagata
     1201 aaatagaatt tgattataat atttaaaata cctaggtagt cgttgtttta aatatagtag
     1261 gaatcggacg ctcagtacgg agcgtctatt tttttaccca attttgaaag gaagtgaact
     1321 tatgaaaata aaaaatcaag aatcaaaagg tcgctctccc ccctttaaaa ccatcacaca
     1381 aataagattc attcaaacat aaaaacagaa aggataggta aaaatatgga acttaaatat
     1441 gtcattccca atatggaaaa aacatttgga caattagaat atgctggtga agggaacatt
     1501 gaacaacgtc gaataaatgg cagaccaacc attctctctc gtagttacaa tttatactca
     1561 acgattcaac gagcagatga tattgttgtc attcttccct ccgaagctgg cgagaaacat
     1621 tttgaatccg acgaaaaagt caaactcatc aacccacata ttaccgcaga aggttataaa
     1681 attggcaatc gaggatttac caattacatt atgcacgcag acgatatggt gaaagcataa
     1741 gaaaggaaag gtgaaaaaat atgagattag cagaaggtat tgtgattgaa aaagaccaga
     1801 catttggcac attgaaattt tccgccttgc gtcgtgaggt tcgtatccag aatgaagatg
     1861 gtacggtttc cgaagaaatt aaagaacgta cctatgactt aaaatcaaaa ggacaaggac
     1921 gcatgataca agtcagtatc cccgcttctg ttcctttgaa agaatttgac tacaacgcag
     1981 aagtggaatt aatcaatcct gtggcagata ccgtagcgac ggctactttt cgaggggcag
     2041 acgttgattg gtacgtgaaa gcagacgatc ttgtattaaa aggacagaca aaacctcatc
     2101 agaaatataa aaaagaagcg tccgaaagtg aaaaataggt gttgcttatg acaaacacac
     2161 cattgatttt gaaagaaatt ccgaaggatg aagccatttc ttttattcgg caataccatt
     2221 attcaaagat actccctaga ttgtgtaaat actttctagg gattttttca gaagaaaaat
     2281 tattaggcgt tgtggaatta ggctggggta cgcaacccct acaaaccata cgcaaactct
     2341 ttcccgacag ttcccttcaa accacagatt atttagaaat tggaaagatg tgttttcttc
     2401 cagaaatgaa tcaaaccaat tattttggca gtcaagctct ttcagctcta attaagtggt
     2461 tgaaagaaca tacggactgt cattttttat atacactggc agatggaatt gagggaaaat
     2521 gtggctatgt ctatcaagcg tccaacttct tttactgcgg gtatttcaag acaagtgtct
     2581 atcgtgataa gcagtcatgg gaaaagatac accctcgaag tgctcgcctt ttattagagg
     2641 aaaatgctcg ctttgaacag gtagagaaaa agcattggct ttcccaggca ttttgcgaat
     2701 acaaagggat tgagaaaatc aatggacgca tgtttcgcta tctctatccg ttgacaaaag
     2761 aagcgaaaaa actgttagga cacactctct atcgacgtca ttattatccg aaagaaaaaa
     2821 atttacgctt tgaaaagcga atcgcttatc agaaatatga agccatttct caaccaactt
     2881 ttgataaaca ggctcgtatc tacaatacac aattattttg ataggtggaa aggaggattt
     2941 ttatgccatt gcttcatgac agaggagagc gaatcaaagc caacgataag cacttggtct
     3001 atcattttgt actaatttca ttgctggtag tttttctagt cgtcctactc ccttttcatt
     3061 ggagagcgtt acaatcggtg aactggcaag cagttcagtt agatacattt ttctatcaac
     3121 ttcatacgcc atacttttgg agcagtattc tcactgctct ttttgtatgc ggacttatca
     3181 gctggcttta ttatcactat cgtatagatt ctataaaaca gttagagcac cgtcaaaagt
     3241 tagctcgtat gattttagaa aatcattggt atgaagccga agaaactcaa tcagagggat
     3301 tctttaaaga tttacccagc aagaaaacca aacaacgaat ccgccatttt cctaaaatat
     3361 attatcgaat gaaagatgga ctaatccata ttcatgtaga aatcacctta gggaaatatc
     3421 aagatcagct tttgcaccta gaaaacaaac tagaaacagg attgtattgt gaattagtgg
     3481 aaaaaacgtt gaaagattct tatgtagagt atgtcctact ttatgatact attggcaatc
     3541 gaattggcat tgaagacgtg gtagctcaag atggacgtgt caaattgatg gaatcggtct
     3601 attgggagtt cgattctctc cctcacatgt taattgctgg gggcactggt agtggaaaat
     3661 cctattttat tctcacattg attgaatctc tcctgcatac aaatgcaaag ctttatattc
     3721 ttgaccctaa aaatgctgat ttggcagact taggggcggt catgaataat gtctattacc
     3781 gtaaagaaga tatgttggca tgtatcaatc aattttacga agatatgatt gatcgcagtg
     3841 aaaccatgaa acaacaccct aactataaaa caggagaaaa ttatgcttat cttggtttgt
     3901 ctgccaattt tcttattttt gatgaatatg tggcaatgat ggatatgcta ggtcgtgaaa
     3961 gtaccaccgt tattcataaa ctcaaacaaa ttgtaatgtt aggacgacaa gcaggcttct
     4021 ttttaattct tgcctgtcaa cgtccagacg caaaatattt tagtgatggg attcgggaca
     4081 actttaactt ccgtgtggct ttgggtcgta tgtctgaaat gggctttggt atgatgttcg
     4141 gaagcgatac acaaaaacaa tttttcttaa aacccatcaa gggaagaggt tacgtggata
     4201 caggaaaaag tgtgattagt gagttttata caccccttgt accaaaaagg tacgatttct
     4261 taggagaaat aggaaaagtc attcaaaaaa agcaatctga gcctgtaccg cacgaagtga
     4321 aaggtacagg ttcagacttg ctttgattgg tgtggcgtta gccacgccaa tcctttagcc
     4381 ccctctatct aacagggggg cacaaataca actgaaaaca ggcaattctc atcaaccaat
     4441 gttgatggta caaaggattg cggaaaatat gaaaggtgta aactcaaggg tcatagttta
     4501 catctttttt agattggagg tttgcgaatg gaaaacgaaa aaatttggat taaggaattg
     4561 aaagaaaagc gactggctta tggcgtttct caaaataaac tggcggttgc ttctcatatt
     4621 accagacctt acctatcgga tattgaaaca ggcaaggcag tccctactca acaggtgaaa
     4681 gaagatttac tgaacgcttt ggaacgcttc aatcccgata acccattgga gatgttattc
     4741 gactatgtac ggattcgatt ccctaccaat gatgtggctc aaattatcgg tgaggtttta
     4801 cgtttgaata tggattatat gctacacgaa gactttggct attattctta tcccgaacac
     4861 tatcgtttcg gtgatattgt tgtcctagtc tctcatgatg taagtaaagg tgttttatta
     4921 gaactgaaag gaaaaggctg tcggcaattt gaaaactttc tattggctca acatcggagc
     4981 tggtatgatt tctttcaaga ttgcatggaa cataaaggta ttttcaaacg cttggattta
     5041 gctatcaacg ataaaacagg gattttgaat attccagatt tggcaaagaa atgtaaacag
     5101 gaagaatgca tttccgtctt tcgaagcttt aaaaattatc gcagtggtga attggttcac
     5161 cgtgatgaaa aaccatacat gggaaacaca ctttatattg gctcattaaa aagtgaagtc
     5221 tatttctgta tatatgagaa agattatgag caatacgtga aaaatgatgt tcccttagaa
     5281 gacgcagaag taaagaatcg gtttgaaatt cggttaaaaa atgaccgagc cacccaagcc
     5341 atgaaagatt tattggcaca tcaacaggcg gaaaaaacag cctttgaaat tatcaatcgc
     5401 tatatccgct ttgcagataa agacgacact aaacgtcgga gtgattggaa aactaatgaa
     5461 cgttgggaat ggtttatcgg taaaaatcgt ggagcattac gcctaaccac acagccagag
     5521 ccttattctt ttgaacgaac attgaactgg ttacatcatc aagtcgcccc tacattaaaa
     5581 atcgcaagca ttttagatgt tctcaacggt acaaccatta tctccaccat gattcaggaa
     5641 gccaaactga cagaaaaaca tgagaaatta attgaacaac aacatctagc catggaggat
     5701 ttgattacat gagcctttta acaaaagaat taaagaagtt agggtttcag tgtggcattg
     5761 agtttcaagc gtatatacaa aatacaggga aatatacgtc tctcattatt gagggaaaac
     5821 ggcaagctgg tgataccatc tatacctatg atttttacaa ggtgagattt tataataatt
     5881 ataccaatcg agtaaccgtc tatggagagc atttaacccc ttttcaatta ttaaggcgtg
     5941 taaaaagcta tatctattat cgagaaaaat atcttaagga aaggaggaca atcacatgaa
     6001 ttttgggcag aatttgtaca actggttctt ggataatgca cagtcattgg tattgttagc
     6061 gattgttgtc attggactgt ttttaggttt taaacgagaa ttttcaaaac tcattggctt
     6121 cttgattatt gctctaatcg ccgtcggact tgtgttcaat gcagctggcg tgaaagatgt
     6181 gttattaaac ttatttaacc gaatcattgg tgcttaacag atatttttca tgataaaata
     6241 ggaagtatat attttgttat gaaaggattt atgaatatgt ttacaaatga tcaatttaaa
     6301 tctcttttaa ttaaaacatt agaaagaaag agctcttcaa attattatga aggaggtaac
     6361 gagattgttt ctaaaatgaa aatatcagag gtaactttag atgagactga cgattttact
     6421 tattataaag gatataaaaa gggctggaat acgctttgca catatcttaa aataagagtt
     6481 ccttttgatg atttagactt ttttgaaagt cataaagatt tgattaccca gacagcaagc
     6541 tccatatatg ataaacaagg tgataatgta ttagtggata ctattttagt accacttcca
     6601 gagaattacg aagtaattaa ctttagtcag ttgaaaatta gtgatgtggt ttcacaagct
     6661 attgaagacg ctgagtcttt tatgagtaat ggtgaatatc aacgtgcctt tgacagagtt
     6721 cacactgctt ttcatggata tttaattgaa atactaaaaa aatatgaaat tacagttcct
     6781 agagacgaaa atctatctaa attatatagt aggatacaac aattaattga aaaagaaatt
     6841 caacctactg aacttgctga tatagtgaag acaacgataa ggtcatcaaa tggaatgatt
     6901 agctctctta atgaagcaag aaataggcat tcacttgcac accctaatac aaatattatt
     6961 ggaaagagag aagcaaaact aataataggt atttcaagta cagttacaga ttatattagc
     7021 ggataccttg ataagtagcg tcattaactg attgctactt tttttatgac tatttttata
     7081 aaaaggatgt gataagaatt ggaaatgaaa gtctatgtgg caaatttagg acggtataat
     7141 gaaggtgaat tagtcggagc atggtttact ccaccaattg atgaggaaga aatggcagaa
     7201 agaatcggtt taaatgagga ctacgaagaa tatgcaatac atgattttga gcttcctttt
     7261 gatgtggacg aatacacgcc gattagtgaa atcaaccgtc tatgtgaagc cattcaagaa
     7321 atcgaaggta cacctattta taatgaactc aaagaaattc aaggcatgtg gtttagtagc
     7381 ttggaagaat tactggaaaa caaagaggat attcattgtt atagtgattg tgattcgatg
     7441 gaagatgtcg cccgttatta cgtggaagaa acaggacagc ttggtgaagt cccttccaat
     7501 ttacaaaatt atattgacta ccaatctttg ggacgtgata tggaaataga gggtaattac
     7561 ctagttacct ctcatggggt atttgaatat tgtcagtaag tttaacaatc cgtgttataa
     7621 ttaaattaat aaatagcacg gagaggtata aattatggta aatgtatttg aaaatcttaa
     7681 actattaaaa ctagacatga aagataaagg ctgggtgata gattcctttt actttcgtta
     7741 caaacagcaa aattatattg tacttgttaa gctatttgaa aaagaggaaa aagttccaga
     7801 atatgctctg ttaaaactag aatttttaaa ggaaaacgat ttttcagata tgctagctgt
     7861 ctatgctaat tcggtaaaat tatatacaga cacgaaaaca ataagagaat attttggtat
     7921 cgaatacagt agtaacttgg gagatgtttt atttcaattt agccaaactc ttgctcgatt
     7981 tattccgaca gaagttagtg agaagaaaaa tgaagaccaa aaagaagcca tgtgtttctc
     8041 attaagtcaa agtgattcag aagatcccag aaaaaaatat tgtttttcag ttagaagaaa
     8101 tcctttaaag ggaaatggtg agctgggaaa acgaagtcct tttaatgaca ataaaacgag
     8161 attgtataga cccagcttat atgaacgatt agggtcagat accaatttaa gtttcagata
     8221 ttcaatgaat ccagatgatg aagaaactga tgaaggtatt attgcaaaat ggacaaaaaa
     8281 taaaattgaa tagttaaagc attgaaagag caatcaccta ttttgattgt tctttttcta
     8341 tttttacgga aaggacgtga agacatgaaa aaaataagaa gttacaccag tatttggtca
     8401 gtagaaaaag tgatttatgc gattaatgat ttacaactcc ctttcccaat tacctttacg
     8461 caaatgacat ggtttatcgt ttctttgttt gtcgtcatac tctttggcag tttaccacca
     8521 ctttctctga ttgacggagc actactcaaa tacttaggga ttcccattgt tctcactggg
     8581 ttcatgtgcc aaaagacctt tgacggaaag aaaccctatg gatttctaaa gtctatcatt
     8641 acctatgctc tacgccctaa agtaacctac gctggcaaac aaatacgatt aaaaaaagaa
     8701 acaatgaatg aatcgattac gattgtaagg agtgaacaac tagatggcat atccgattaa
     8761 atatatggaa gataatctcg tatttaatca tgatggcgaa gtattcgctt attatgaatt
     8821 aattccctat aattacagtt ttttaagttc cgatgaaaaa attcaagttc atgataattt
     8881 ctgtcaattg attgcccaaa atcgtgatgg caagattcat gctctgcaac tagcaaccga
     8941 atcaagtatt cgagccacac aggaacaatc gaaaaaagaa atcactggac gattaaaaga
     9001 gatagcttac gaaaaaatag atgaacagac cgaagcgtta atttctatga ttggtgacaa
     9061 tcaagtagac tatcgctttt ttattggttt taaactctac ctcaatgaac aggaagtatc
     9121 cgtaaaaaat gttgggaaag aaattcaaaa agcatttgcg gaattctttc atggtgtgaa
     9181 tcacaaatta atgggcgatt ttgtttctat gcctatggcg gaaatcgaac gcttttctaa
     9241 gatggaacag ttgttagaaa gtaaattatc cagacgcttt cagattcgta aattggagaa
     9301 agatgatttt ggttatatta ttgaacatct ttacgggcaa acaggtgtcc cttttgatga
     9361 ctacgactac catttaccga aacgatacga agataaaaaa gtgttggtaa agaaatacga
     9421 tattctcaaa cccactcgct gtttaatcga agaaaatcaa cgctatttac ggattgaaca
     9481 ggaagatacc actacttatg tggcgtattt tacaattaat agtattgttg gtgaattgga
     9541 tttccctaat agtgaaattt tttattacca gcaacagcag tttactttcc ccgttgatac
     9601 cagtatgaat gttgaaattg tcgccaataa aaaagcctta tctaccgttc gcaataaaaa
     9661 gaaagaactg aaagatttag atagccacgc atgggaaagc gacaacgaaa ccagtactaa
     9721 tgtggtggac gctttagaat ctgtcgatga attagaaagt aatttagacc aaaccaaaga
     9781 atctatgtac aaactaagct atgtggtacg ggtatcagca aagaatttgg acgagctgaa
     9841 acaacgttgt gatgaagtaa aagattttta tgatgatctg tctatcaaat tagtacgacc
     9901 ttttggcgat atgctaggct tgcataatga atttattccc tcaagcaagc gatatatcaa
     9961 tgactatatt caatatgtca cgtcggattt tttggctggt cttggtttcg gtgctacaca
    10021 aatgattggt gaaaattctg gtatttacgt cggttacaat ctcgatacag gcagaaatat
    10081 ttatctccaa cctagccttg caagtcaagg aattaaaggc tctgtaacaa atgcattagc
    10141 gtccgctttt attggttcat taggtggcgg aaaatcattc tctaacaata tgctggtcta
    10201 ttattcagta ctctttggcg gacaggcaac cattgttgac ccaaaagctg aacgtggtga
    10261 atggaaagaa accttacctg atattgccca tgaaatcaat attgttaatc tcacgagtga
    10321 gaacgacaat aaagggttac ttgaccctta tgtgatttta aaactcccga aagattcaga
    10381 aagccttgcc attgatattc tcacgttctt aacaggtatt tccagccgag atagcgagaa
    10441 gtttcctgtc ctgcgtaaag ctattcggag tgtaactcaa agcaaacaac gagggttgtt
    10501 attggtgatt gatgaattgc gaaaagaaga tacgcccatc agcaatagta ttgctgacca
    10561 tatcgaaagc tttgtcgatt atgattttgc ccatctgtta ttcagtgatg gcagtgtcac
    10621 ccaatccatt agcttggaaa aacaactcaa tattattcaa gtggcagatt tggtcttacc
    10681 cgattccaat agctcttttg aagaatacac taccatggaa ttattaagtg tggcaatgct
    10741 gattgtcatt agtacctttg ctttagactt tatccactct gaccgttcca tttttaaaat
    10801 tgttgacctt gatgaggctt ggagtttttt acaagtggca caaggaaaag ctctatctat
    10861 gcgattggtt cgagcaggac gtgccatgaa tgcaggggtc tatttcgtta ctcaaaacgc
    10921 ggacgattta ctagatgaaa agatgaagaa taatattggc ttgaaatttg cctttcgttc
    10981 cactgaccta gtggaaatca aaaagacctt agaatttttt ggtgtggaca aggaagatga
    11041 aaacaatcag aaacgcttac gtgaattaga aaatggacaa tgtttagttt cagacatcta
    11101 tggtcgtgta ggggttatgc agtttcaccc gatttttgaa gagttgcttc atgcctttga
    11161 taccagaccg cctgtgcgaa atgaggtgga agaatgacac aaaaacaaaa gaaatttctt
    11221 cactatagtt ggataacgct cctttgtgtg ggcgttattt tacttttatt aggcacgctg
    11281 ggcaatgcag tacaagcgac aggcttagtt gatgaaacca ttgatacaag caatgaatac
    11341 tccaagtatg gtttgaatca atatcagctt gattattatg tggacaatag ctggggctgg
    11401 cttccatgga attggagtga tggcatagga caatcggtga tgtatggatt gtatgccatt
    11461 actaatttta tttggacaat ttctctttat ctatcgaacg ccacaggtta tttggtgaaa
    11521 gaagcctatg ccttagattt cattagtcaa acatcccaag caattggcga aaacatgcag
    11581 acgattgcag gcattacacc gaatggcttt tccagttcag ggttttatgt cggtttcctc
    11641 cttcttttta ttctcattgt tggaatctat gttgcctata caggattggt taagcgagaa
    11701 acgacgaaag tgatacgagc tgttttaaac tttgtcgtgg tgtttattct atcggcttcc
    11761 tttattgcgt atgcacccga ttatattgcg aaaatcaatg atttttccaa agatgtcagt
    11821 accgccagtc tgaatattgg gacaaaaatt gttcttccta acacggatag tcaagggaaa
    11881 gacagtgtgg acatgatacg tgacagctta ttctctgttc aagtaaagca accatggcta
    11941 ttgcttcaat atggctccac tgatgtagaa gcgttagggg aagaacgtgt ggaaagttta
    12001 ttgtctacca gtccagatac aaacaatggt gaagatagag aaaatgtagt gattgaagaa
    12061 attgaagatc atgacaatac ctatttaacc ctaccgaaga cgatttccag attaggaaca
    12121 gtcttctttt tgtttgtatt caatattggt atctcgattt ttgttttcct tctaacagga
    12181 atcatgattt tttcgcaagt gctatttatt attttcgcta tgtttttgcc aatcagtttc
    12241 ctattaagta tgttgccgag ttttgatggc atgggcaggc atgccattac caagttattt
    12301 aatgtgatta tgacaagggc tggtattacc ttgattatta ccgttgcctt tagtatttcc
    12361 actatgcttt attcgctgtc agcaagttct ccctttttca tgattatgtt tttacaaatt
    12421 gtgacctttg cagggattta ttttaaactg ggcgatttaa tgagcctatt cactttacaa
    12481 agcaacgact ctcaaaacat gggcagacaa gtgtttcgca gacctcgtca aatgatgaat
    12541 cgacaaacca gaagatttca acgcagtatg agtaagattt ttcgtggaaa agcagggtca
    12601 acgaagcaaa agacaatgac aacaaagcag aatcaaacca ataaagctaa ccatactcgt
    12661 caaaatgaac ggactacacc aaagaaagaa acagcacttt ccaatgtgaa aaagcaacaa
    12721 ggcggtatcg ggcaacgatt aggtgaaaag acagcccatg tattggacac gaaaaatcgt
    12781 ctagtcaata aaagaaagca ggcaaaacaa cagatacagg cgacaccaac ccatgtcaaa
    12841 tatgcccttc atcaaggaaa agagaatgtc actcataatg taacagactt taaacaatct
    12901 atggcagata ccaaagctca acgcaaacaa cagcgtatga accagcagga gcaaaaacga
    12961 aagaacattg ctcaaaagcg tttggagctg gataaagcaa aagaaaaaag acgaaaagaa
    13021 aacccatcat ctcctgttca gaataaccag cagcatgttc gcaagcgtca gcaaaccgtc
    13081 acgcctgttt tgtcacaaaa cactaaacgt gaaaatcatc agcgaccatt gaaaaaagag
    13141 caaaaacaaa agacaccacc gaagcaattc aatcagagga agctaaataa aagaacggat
    13201 aagcgaggac aacaaacatg aagctaaaaa taacagtgat ttgtagtgtg gtcttctctc
    13261 tcttcttttt tctcttatta ttcctagtca ttttctttgc agatgatacg gacagtggcg
    13321 aaaacaacaa ggattcttct attccacaag gcggtgtgac cgtttcacca gaagtgttgg
    13381 cacaccgtcc gttgattgaa aaatatggta aggaatatgg gattgaagac tatgtttctt
    13441 atatcttagc cattatgcaa gtggaatcgg gcggtacagc agaagatgtt atgcaaagtt
    13501 ccgaatcttt gggtttaccg cccaacagtt tgagtaccga agagtccatc aaacaagggg
    13561 ttaaatattt cagtgaatta ttaaccagtg cagaacaaca aggagtggat atagattctg
    13621 ttatccaatc ttataattat ggcggtggct ttttaaatta tgtgaggagt catgggaaaa
    13681 aatataccta tgaattagcc gaacagtttt ctaaagagaa gtcgggtggt caaaaagcag
    13741 actatcccaa tcctatagcc atacctgtga atggtggttg gcgatataac tatggaaatc
    13801 agttttatgt tcagttggtt tcacaatacc taaccgacac ttccccaaca gaatttgatg
    13861 gtgaaaccgt gcaagtcatt atggacgaag ccttgaaata cgaagggttt ccctatgtct
    13921 ttggaggggc gtcgcctacc acctcttttg attgtagtgg cttaatacaa tgggtgtatg
    13981 acaaagctgg catttctctc cctcgtgtcg cccaagatca gtatgacgct acgcaagaaa
    14041 tctctatgga agaagcccaa gcaggcgacc ttatcttctt tcattcaacc tataatgcag
    14101 gcacatatgt gactcatgtg gcgatatatt tagagggaaa tcgcttttat catgcaggcg
    14161 acccaatcgg ttatggcgac ttaagcagtc gttattggca agaccatctg attggggcta
    14221 gacgtgttat tcataactaa gaaaggaatg aatcaaatga ttataaaaat cgagcgaaaa
    14281 gaaaagaagg agaaaccaaa gaaatctaaa aaaccgagca agcaaagaaa agttccgatg
    14341 attaaagttg gcacgcataa gaaattaacc tttgttttat gggttttatt gattggtagt
    14401 gtcggatttg gaatctataa aaattttact gccattgaca ctcatactgt ccgtgaaaca
    14461 gaaatcatta aacagcagat tgtcgatacc aaccaagtag aaagttttgt gaaatccttt
    14521 gcgaaagact acttttcgtg gcaacaatcc caagaagcca ttgataaacg aaatgaaaaa
    14581 ttgacccatt atttgacgga agaattgcag gtattaaatg aagaaatgat tcgtaaggat
    14641 attcctacta gttctagtgt gaacgatata caggtgtggc aggtttctca agtgaatgag
    14701 aacacctttg aggtactgtt ttctgttgaa caagttatta ccgaagacaa agacaaggaa
    14761 actatatcgt ctagctttca tgtggttgtc catatagatg aatcagataa tatggttatt
    14821 atcaaaaatc cgacaatgag taagaaacct caaaaatcgg actaccaacc caaacagcta
    14881 gaaagtgacc atacagtaga tacagaaacg atggacgaaa tcactagctt tttagaaacg
    14941 ttcttccagc tctatcctac cgccacagaa aaagaattga cttactatgt aagtaatcat
    15001 gtgttaccta tgattaacaa ggaatatgtt ttcgaggaat tggtgaatcc tatctttacc
    15061 agaaaagata accaagtaat cgtgaatgtc gctgtgaaat atttagatca agaaacaaag
    15121 gcaacccaaa tctcgcaatt tgagttgata ttagaaaaac aagataattg gaagattgta
    15181 aaataacaaa tattggtaca tgattacaga tactttgtaa tcatgtactc tttttgataa
    15241 aaaattggag attcctttac aaatatgctc ttacgtgcta ttatttaagt gactatttaa
    15301 aaggagttaa taaatatgcg gcaaggtatt cttaaataaa ctgtcaattt gatagcggga
    15361 acaaataatt agatgtcctt ttttaggagg gcttagtttt ttatgccctt ttgggttttt
    15421 gaatggagga aaatcacatg aaaattatta atattggagt tttagctcat gttgatgcag
    15481 gaaaaactac cttaacagaa agcttattat ataacagtgg agcgattaca gaattaggaa
    15541 gcgtggacaa aggtacaacg aggacggata atacgctttt agaacgtcag agaggaatta
    15601 caattcagac aggaataacc tcttttcagt gggaaaatac gaaggtgaac atcatagaca
    15661 cgccaggaca tatggatttc ttagcagaag tatatcgttc attatcagtt ttagatgggg
    15721 caattctact gatttctgca aaagatggcg tacaagcaca aactcgtata ttatttcatg
    15781 cacttaggaa aatggggatt cccacaatct tttttatcaa taagattgac caaaatggaa
    15841 ttgatttatc aacggtttat caggatatta aagagaaact ttctgccgaa attgtaatca
    15901 aacagaaggt agaactgtat cctaatatgt gtgtgacgaa ctttaccgaa tctgaacaat
    15961 gggatacggt aatagaggga aacgatgacc ttttagagaa atatatgtcc ggtaaatcat
    16021 tagaagcatt ggaactcgaa caagaggaaa gcataagatt tcagaattgt tctctgttcc
    16081 ctctttatca tggaagtgca aaaagtaata tagggattga taaccttata gaagttatta
    16141 ctaataaatt ttattcatca acacatcgag gtccgtctga actttgcgga aatgttttca
    16201 aaattgaata tacaaaaaaa agacaacgtc ttgcatatat acgcctttat agtggagtac
    16261 tacatttacg agattcggtt agagtatcag aaaaagaaaa aataaaagtt acagaaatgt
    16321 atacttcaat aaatggtgaa ttatgtaaga ttgatagagc ttattctgga gaaattgtta
    16381 ttttgcaaaa tgagtttttg aagttaaata gtgttcttgg agatacaaaa ctattgccac
    16441 agagaaaaaa gattgaaaat ccgcaccctc tactacaaac aactgttgaa ccgagtaaac
    16501 ctgaacagag agaaatgttg cttgatgccc ttttggaaat ctcagatagt gatccgcttc
    16561 tacgatatta cgtggattct acgacacatg aaattatact ttctttctta gggaaagtac
    16621 aaatggaagt gattagtgca ctgttgcaag aaaagtatca tgtggagata gaactaaaag
    16681 agcctacagt catttatatg gagagaccgt taaaaaatgc agaatatacc attcacatcg
    16741 aagtgccgcc aaatcctttc tgggcttcca ttggtttatc tgtatcaccg cttccgttgg
    16801 gaagtggaat gcagtatgag agctcggttt ctcttggata cttaaatcaa tcatttcaaa
    16861 atgcagttat ggaagggata cgctatggtt gcgaacaagg attatatggt tggaatgtga
    16921 cggattgtaa aatctgtttt aagtacggtt tatactatag ccctgttagt actccagcag
    16981 attttcggat gcttactcct attgtactgg agcaagcctt tagaaaagct ggaacagaat
    17041 tgttagagcc atatcttagt tttaaagttt atgcaccaca ggaatatctt tcacgggcat
    17101 ataacgatgc tcccaaatat tgtgcaaata tcgtaaatac tcaactgaaa aataatgagg
    17161 tcattattat tggagaaatt cctgctcgat gtattcaaga ttatcgcaat gatttaactt
    17221 tttttacaaa tgggcttagt gtttgtttag cagagctaaa aggatatcag gttaccactg
    17281 gcgaacctgt ttgccagacc cgtcgtctaa atagtcggat agataaagta agatatatgt
    17341 tcaataaaat aacttagtgc gttttatgtt gttatataaa tatggtttct tattaaataa
    17401 gatgaaatat tctttaatat agatttgaat taaagtggaa aggaggagat tgttattata
    17461 aactacaagt ggatattgtg tcctatttgt ggaaataaaa caagactacg aatacgagtg
    17521 gatactatac ttaaaaattt ccctttatac tgccccaaat gtaagaacga aactttaatt
    17581 aatgttcaaa aaatgaatat aataacaatc aaagagccag acgccaagac gcagagccga
    17641 taatttgaga aatgaaactc tcatcttatc ggctcttttt gtttatctga attttactga
    17701 ctagccttca atatttcttg cttcattgat accttttgct agtgcttcca ttaaggatag
    17761 ttctttgtct gtaaagctat ccatgtattt ttctacctgt aaccttcgag tgcttttaat
    17821 caaattatct gtaggtaaga aaaattcatc aatagataca tggagtaatg atacaagatc
    17881 atacagcact tgtgtacttg ggtgttgtcc tttgttttct atatttgtta aataacgtgg
    17941 gtcaatttca atcattgttc ccacttgttc acgagtgaga ccccgtttca ttcgagcctc
    18001 tttaatcgct aaaccaacgg ctctaaaatc gtatttatct tcttttttac gcatactaaa
    18061 tcacctctat acattttact gttcctatat aaccataaac aggtatagaa aaacatgtta
    18121 tatagtttat gagttcctat agaacactgt ggaatttatt aatgcgatga atccaatttc
    18181 aaatagaaag gtcgctgatt ttatttacct atacaacttt ataaaattta gtcatactcc
    18241 tagaaagtag ataaaattgg cgacttaatg gagggaaaag tcgccatgag aaagataatc
    18301 tgtcatctag ttctcttaat taagttctta tcaaaaaaac ttatccacct gtactggata
    18361 gatatgacca tcaatgtggt tttgcagatt acatagatag aaaaatcaaa gcatatgaac
    18421 agagaaaaca atctgtttat gtgctttttt ggtcacttaa taaatatctt ttaggatttc
    18481 tcttcattta tgcaacaaat ccccctttcg tgtcggggtt tagtatgaag ggagataaag
    18541 aagcacatgc cactcccttt cacgacagaa agggggtgaa aagcatgaaa ccatcttctt
    18601 ttcaagaaac catagaaaat cagtttgact atatctgcaa acaagttatt gaagatgaac
    18661 gaaaagatta cttcaaacat ctagacagac tatcagcaaa agaagtctcg ttttctgata
    18721 tagataacta ccttgtcaac tctttttcta ctgttgatac gtacgtcact gatttccaac
    18781 tatttaaatt atttggatta agaatcaatg ttgaaagtga tttattaagt gaagccctgc
    18841 gtcatctttc agagaaaaaa cggaacatta ttttacttca ttactttatg gatatgagtg
    18901 atgtggagat tgcggagtta ctaaatttga atcgttcgac tgtttatcgt catcgaataa
    18961 gtggactagc catgattaaa gaattcatga aggagtgtaa agaatgaaaa cagcttatcc
    19021 aagggttccc ttccccctca ttgtaaaggc gacagatggc gacgtggaag caattaatca
    19081 gattgttaaa cattatcgag ggtatacctc aaaacgttca ttacgtcgca tgacagacga
    19141 atatggaaat tctcatatgg ttattgatga aaccctacgt ggcagaatgg aaacgaaact
    19201 catctctaag attttatcgt tcgaaattaa atagtcccat tttttcgtgg aagcgtgtcg
    19261 aatcgtatcc acgcttcccg atttgggagg tttgttattc catcaaagca tattgtgtgt
    19321 tcagtaggtt ttgataggct aacaagccaa acgttctttg acaaccaaat aaaggcaatc
    19381 gaatacgttt cggtaagaaa agagctgatg aactaacacg ccatgaccta caaaattagt
    19441 gagcgattca tgttagtaat tcgaaagtaa tctttagcag gattgctgcc atgactttct
    19501 tatcgtgata atgatactcc cgtatagcca tagtccgagc gttagaagcg tcacaggcaa
    19561 tgggtacggc tacatgagaa ccatgcagaa gtgaaattcc tgtgagcttt gctagagctg
    19621 ttcgattgct aagatattct tctcttgtca gtgtattatt ataaaactat ttgatataat
    19681 tataggtgaa tattggagtt ttcctagcct ataattggga aaggagtaat aatgataacg
    19741 gtcacaaaaa aggatttagt tgagctagga tatggaactt ctttttcagc agacatcata
    19801 aaaaaagcaa aagaattgat gattacaaaa gggcatatct actatcaatc tcgaaagcta
    19861 gatagagtcc ctcgtgaagc tgttgaagaa attctaggaa ttcggttttc aaatgaaaac
    19921 aggtctgagt agtttttgca cagtaaggag taaaaactat ggttaaagac ccaataaaaa
    19981 aagcaaagaa tggaacctat tattttcgtg caaatctagg ttatgattct aaagggaaaa
    20041 aaattcaaaa atatcgtagt ggattcacta ctaaaaaaga agcaagagaa gaatattcga
    20101 aactgctatt gatgaaacca gaagaattaa gtgagaataa ggataaaatg acgtttaaac
    20161 attatatctt tgaaattttc cttccatggt ataagacaca ggtaaagctc agaacatatg
    20221 aaaatcgctt accaactatt aagaagcatt tctcttattt tgataaaatg gctgtttccg
    20281 atattgagcc tattgatgtg caaaattggc aactaaaatt atcaaagaag tgtaagtctt
    20341 cttatgtaag agctgttcaa ggactatttt cagttgctat ggatcgagca attgtccttg
    20401 ggataaccac cacaaatcca tctaagatta ttggcaatgt gaaaaagcaa aagtctaaaa
    20461 ttgaattttg gacaaaagaa gaatttgaaa aagtaatctc tctaatttac aaagaagatt
    20521 actatcaaca ctttttattt atctctctgt ggtttttatt tatgactgga atgcgaattg
    20581 gtgaagctac tgccattcaa tgggaagata ttgattttga ctcaggagta ctaaccatca
    20641 acaaaacact ctattacaag aatcaatcga attatagatt tgttgaacca aaaacaaagg
    20701 cgagcgttcg tcatattgta ttagataaat gcacattaac ttatttatcc gaatggaagg
    20761 aagtacaaca aaatctaatt cagacagact ttgtaatgag ctataacggt attcctaccc
    20821 aaaaacatac actatcatat gctattgaac gctatgctaa gctggctggt atccatcgaa
    20881 tcagaatcca tgggttacgg cattctcatg cttccttgtt aatcagtatg ggagaaaatc
    20941 cacttatcat taaagatcgt ctaggacacg aagatattga gacgacttta ggaacgtatg
    21001 gacatcttta tcctaacagt aatttcgagg tagctaacaa attaaatgga gccatttcct
    21061 ttaaagaagc aaaacaaaat tatgatactt caccaaagaa tcaatttact gtagactact
    21121 tgcgaaacaa agaaatgaaa aaagtgcaat aaaagtgcag taaaaagata agaagagcca
    21181 gaaacccttg gtataagagg atttctagct ctcctacaac tattcccact ccactgttgc
    21241 tggtggttta gaagtgatgt catacacgat acggttgacg tgggctactt cgtttacgat
    21301 acgtacagag attttttgca agacttccca tgggatacgg gcaaagtcag cggtcattcc
    21361 gtcgattgaa gttacagcac ggataccgac tgtgtagtcg taagtacgtc cgtcacccat
    21421 aacaccgaca gagcggatcc ctggaagaac agtgaaatat tgccagatat cacggtcaag
    21481 tccagcagct gcgatttctt cacgcaagat agcatcagat tcgcgtacga tttctagctt
    21541 gtcttcagtg atttcgccaa gaacacgaat accaagacca ggaccaggga atggctgacg
    21601 ccaaacgatt gaatcaggca tgcctaactg agtccctaat tcacggactt cgtctttgaa
    21661 taatgtgttt aatggttcga tcaattcaaa ttgcatatct tctggcagtc cacctacatt
    21721 atggtgagat ttgatcgtct gtgctgtttc tgtaccagat tcgataacgt cagtatacaa
    21781 cgttccttgt gctaggaaag agacgccttc ttcaccagca agttttgttg cttcgtcatc
    21841 aaaaacatat acgaattcat tcccaatgat tttacgtttt tgttctgggt cagatacacc
    21901 tttcaacttg tctaagaagc gatctcttgc atcgactttg atgatgttca agccgaattt
    21961 tccgcctaga ctttccatta cttgttccgc ttcgcctttg cgtagcagac cgtggtcaac
    22021 aaagatagat gtcaattggt caccgatcgc tttttgtaaa agaaccccaa cgacactaga
    22081 atcaacgcca cctgaaagac caagcaagac ttttttgtca ccaacttgtt cacggatttt
    22141 ttctacttgc atatcgataa agttatccat tgtccagtta ccttcacagt gacaaacatc
    22201 aaaggcaaag tggcgcagca attcgattcc gtattcggaa tgacgtactt ctgcatggaa
    22261 ttggatacca taaaaattac gtgttgtgtc ttggatagaa gcaatcggac aatctttgct
    22321 tgttccgact gtttcaaagc cttcaggaac tttagttacc aagtcaccat ggctcatcca
    22381 tactgtttgt tgttttggtg tttctttaaa caagacagct tgatcgcttg ttacttctaa
    22441 caaggctttc ccatattcgc ggtttttagc aggctctacg gaaccgccaa gtttgtacgt
    22501 gatcaattgc ataccatagc aaatccctaa tacaggaata cctaaattga agatctcagg
    22561 atcgatccca aatgcattct catcatatac actgtttggt ccgccagaaa gaatgattcc
    22621 ctttggattc atcgctttta cttcttctgc agtaatgcgg tggctcaata attcggaaaa
    22681 gactccaaga tcacgaatac gtcttgtgat caattggtta tactgactac cgtagtctaa
    22741 tacgataatc ttttcaacgt tcgtcatatc ggcaacgttt gtcaaattta ttacccctat
    22801 ccctttaaat tttatctcaa aatagtcaaa ctattttaaa atgctaatat tttcgcatga
    22861 aaatcgaatc gatgatatga ttttcagttt tatggagaat tatatcggct cttcctcgtg
    22921 taggcaagat atattcctgt aaatttttca aattcacatt tttccataca tcttttgcca
    22981 ttttaaaggc ttcttcacga tctccgatag caaaacgata ataataattc tctggatttt
    23041 ggaaagccgt atccagtaac gcaccaaaac gatccaaata ccatttttcg atcagcacgg
    23101 gatcggcatc gacatagaca gaaaaatcaa aaaagtcgct gacgtagatt tgctgattcg
    23161 caggtaattg aagcgtattg atcccctcaa cgatcaagat atcaggctgc tggatcaatt
    23221 cgtacttgtc tggaatgata tcatacacat catgtgagta aacaggtact tttatctctt
    23281 cctgaccaga ttttacacgg ttcaagaaat cgatcagcat ctccatatca taactttcag
    23341 gaaatccttt acggtccatg attccacgct cttttaatat acgatttgga taaagaaatc
    23401 cgtcagtcgt gatcagctga acgtttcttc gtttgaaggt acgagacaaa atcgtctgca
    23461 gcagtctggc tgttgtactt tttccaacgg ctacacttcc ggcgatcccg ataataaaag
    23521 gcggtacttc tacgtattta tgaagaaata aacctttact caagaacaaa gattcaaatt
    23581 ctttcatata aagataaatc agatgagcaa gaggtacata gatatctcga acatcctgca
    23641 tggaaatgcg gtcattcaaa cttttgatat tatctagttc atcttgtgtc aaaggtgctt
    23701 gcccattacg ataaaattct cgccattctt ctcttgccac acggtagtag ttcattggat
    23761 cattcatatt agcctcctgc gttctcccat caatggaact attttaacac aaaataaacg
    23821 caaaccccac cacttaagag agattgccga tctttttgta taatctttat aatagaaaga
    23881 aacggagtct tattcttgac ttgcgcacgg atacataaaa ggatagactg ttgtcatgaa
    23941 agaaatgaga aggatggaag acatgacaaa tcattactat tctgaacgcc cagatacggc
    24001 gcacgatttt gaacaatggg cttttgagtt aaaaggcaga acctttcaat ttgtaacaga
    24061 ttctggtgta ttttcacgtg aaacagtgga ttatggttca cgtgtcctga ttgatgcttt
    24121 cgattgggaa gagttacctg atgaaggaaa gatcttagat gtgggatgcg ggtatggacc
    24181 gattgggtta gctttggcat ttgcgacaca gcggtttgtt gaaatggtcg acattaatga
    24241 acgagcggta agtctagcgc aaggaaacgc aaagcgtaac caaatcgaac atgttgatat
    24301 ccatcaatcg aatatctatg aagcagttca tgaagaaacc tatgcagcta tcgtaagcaa
    24361 tccgccgatc cgtgctggaa aaaaagttgt acatgaaatt ttgacaggcg catatcctcg
    24421 gttgaagaag ggcggtacac tgacaattgt gatccagaag aaacaaggag cgccgagtgc
    24481 gcaaaagaaa atggaagaaa catttggtaa tgcagaaatc gtcacaaaag ataaaggata
    24541 ttatatcatc aaaagtgtga aagaataact agctgaaaaa tagtggagcg acgaaagagt
    24601 ggaactgggc gtgcatgtac gggtacgtat cagttctttt tttgttgaga agtttttaaa
    24661 aacaaagaac tattttttct tcaaaaagaa atagtaggaa cagagtcgtt gttttttacg
    24721 ataaaataaa taagatacag aacttgtata gaaggctgcc aagtcggtag ataaaggagg
    24781 tttttatcaa aaaacatact ttcctttttt ctctattctt ttcttggggg ttttggtaca
    24841 ctgataggga atttagatag aagggagcca ataggatgaa gctgaccatc agagatatcg
    24901 cagaaatggc aggcgtatca gtaacaactg tctcacagat tttgaataac aaaggaagca
    24961 gatttagtga taagacaaga aaaaaagtgt tgtcgatcgt gaatgaacat cattataagc
    25021 ccgattattt cgcttcaaat gtgatcaatc gacattcaaa gaccatcgga atgatcgtcc
    25081 ctgatgtcac tgatttcttc ttctccaaac tgatcgaagg tgtagagagc tatttgaatc
    25141 ctttgggcta tgtgatcatg ttatgcaatt ctcgtcatag ccaagaaaat gagatcaagt
    25201 atttacaaga gctttcccac cgctcagtgg acggaatctt gctggccaca ccaaatattt
    25261 tacctgagaa atatgcatta gacagcggtt tttatcaaaa aatgccaatc attttaatcg
    25321 atcgcggatt gaatcgtcgg gataacggac ggcttatcgt aaaggaatat gagggcgcct
    25381 atcaagctgt ttcgctgttt attgaaaatg gccatacgaa gatcggcatg ctgaaggaaa
    25441 ccactggata ctatcaatta gaagaacgtt tcaacggata tcgtcatgcg ctgaaagatc
    25501 atggcctgcc ttttaatggg aaatttgttg aacatggaga gttgactgtc caaggtggat
    25561 atactgcatc aaaaaaatta ctcaaacata aagatatcac ggctattttt tgcgggaatg
    25621 atgccatggc gatcggatgc tatcaggcga tcgatgaatt gggcaaaaaa atcccagaag
    25681 atatctcagt cataggattc gatggattaa agctgtcaga atacatgatt ccgcaattga
    25741 cgacagtgca gcagccaagt tttgatattg gattttatgc tgcacgtttc ctgatcgata
    25801 cgatcgaatt tcctcaaaga aaagttccga acaaagtgtt cgaaacaaaa ttaattattc
    25861 gtgagagcgt aaaagtattg acaaagggct aactcggcgg tatattgctt atgtaagcat
    25921 ttacaaaggc tagttagtgc tttttttatt tttagtaaac cagtttacta aagtggttta
    25981 cctttcctaa aaataatgta taataccgaa tgaagacaag gaggatcagg caatgcgaat
    26041 ggtggatctg attgaaaaaa agagggatgg aaacgagctg tcgaaagagg aaatcgagta
    26101 catcgtcacg aactatacga atggaaagat tccagattat caagtcagtg cattattgat
    26161 ggcaattttt tatcaagaca tgacaaatga agaaatcacg aacttaacat tggcgattgc
    26221 taattctggt gatgtcatcg atttgagttc tcttgaagga ataaaggtag ataagcattc
    26281 gacaggtggc gttggtgaca cgaccacatt gattttagcc cccctagtag ctagtgtcgg
    26341 agtgacagtg gctaaaatgt ctggacgcgg tctaggttac acaggtggta cactagacaa
    26401 gctagaagca attcccggat ttcagatcga gctttcggat gaagaatttg tacgcattgt
    26461 taatgaaagt aaagtagcgg taattggtca atcaggaaac ttggcaccgg cggacaaaaa
    26521 attgtatgcc ttgcgtgacg tcacagcgac cgttgattct cttccgctga ttgccagttc
    26581 gattatgagt aaaaaaatcg cggcaggagc agatgcaatc gttttggatg tgaccactgg
    26641 agacggtgct ttcatgaaga acatcgaaga tgcaagacgt ctggcaaaga ccatgacgag
    26701 cattgggaaa ctggctaacc gagaaacagt ggcggttatc tcagatatgt cagaacctct
    26761 tggcgaagct atcggaaata gtctagaagt tgtcgaggca atcgaaacat tacaaggaaa
    26821 tggtccagaa gatctagtag aaatgtgcta cgccttagga agccaaatgg ttgttcttgc
    26881 tggcaaagct aagacaaccg atgaagcaag aacgttgctt caagaagctc tggaatcagg
    26941 taaagcgtta gcaaaattca aagaaatgat ccaaaatcaa gggggagacc cagcgatcgt
    27001 ggaacatcca gaacgaattt tgactgcacg ctacacaatg gagcttcctg ctaaacaaag
    27061 cggagttgtg tcaaaaatcg tggcaaatga attaggaatt gctgcaatga tgctaggtgc
    27121 tgggcgtaaa accaaagaag aagatattga tcacgctgtt ggattgaaac tgcataaaaa
    27181 aattggtgac actgtgacaa aaggtgagtc actattgacg atctatagta acgacgaaga
    27241 aatcacttct gtcattgaat tattatataa aaatattgaa attggtgaat cggcaatgaa
    27301 gccaacgttg attcatgaca tcatcacaga ataaaggaaa aaagcggact ttaccgtttt
    27361 aaagaaaagg ggaaaagaaa tggaactaaa ccgaatgatc gaccatacta ttttgaaagc
    27421 agacgcatct aaagaagctg tgatgcaaat tatcgaagaa gcaaaaaaat accattttta
    27481 ttctgtctgc atcaatccag catgggttgc gctagcgaaa gaacaattac aaggtgagcc
    27541 agtagccgta tgtacagtaa tcgggtttcc tctaggagca aacacacccg agacaaaagc
    27601 atttgaaaca acagatgcca tcaataacgg tgcagatgaa gtcgatatgg tcatcaatat
    27661 cggtgctttg aaatcaaagg atgatcaaca agtccaaaaa gatatcgaag cagttgttga
    27721 agcagcaaaa gatcgtgcgc ttgtcaaagt tattattgaa acatcgttat tagatagaga
    27781 agaaatcatc cgagcttgcg aaatagcaaa agctgcaggc gctgattttg tcaaaacatc
    27841 aactggtttc tcaacaggcg gagcaaaggt agaggatgtc cgtttgatgc gtgaaactgt
    27901 aggaccagaa atgggtgtca aagcttccgg cggtatccat aacgaagaag aagcaatggc
    27961 aatgatcgaa gctggtgcta caagaatcgg aacaagcgca ggagtagcaa tcgtatctgg
    28021 ttcaactggt gaaggctatt aattttttca aaggagaagc tcatggcaga actcaaacaa
    28081 gaatggatca acacagctat tgaagcgtta gataaagcct atgttcctta ttcccatttt
    28141 ccggtaggcg cttgtctcgt aacggaatca ggcaagattt atcaaggcat caacattgag
    28201 aatgcatcat ttggattaac gaattgtgcc gagcgcacag cttttttcaa agcagtatct
    28261 gaaggagaaa aaacatttac gcatctagtc gtagcggggc acacccccga tcctatctct
    28321 ccttgtggtg catgtcgaca agtaatggca gaattctgtt cccctgatat gccggttacg
    28381 ctagtaggag acaatggtgt gacgaaggca acgaccgttc gtgcactgct gccttatgca
    28441 tttactgaaa aagatctata actcatgttc attcagtcag ctgactgttg aaaaataaaa
    28501 caattatttt aggaggcttt acagaaatga aaaaagcaaa attatttggt ttaggtgctg
    28561 tcgcactagc agcagggtta tttttaggtg catgcggcaa caacggctct actgattcat
    28621 ccggtggcaa aagctcatca gacacaacaa ctgcagcatt gatcacagac acaggtggtg
    28681 tagacgaccg ttcattcaac cagtcagctt gggaaggact agaaaaatgg gggaaagatc
    28741 aaggactttc acgaggaaat gatggcttcc aatatttcca atcttcaaat gaatcagatt
    28801 acatcccaaa tattgaccaa gcattgaatg ctggattcaa aacgattttt ggtattggtt
    28861 ataaactaaa accagcgatc caagaacaag caacaaacaa tacaggtacg aactttgtta
    28921 ttatcgatga tgtcatcgat ggattagata acgttgtatc tgcaactttc aaagacaacg
    28981 aagcttctta tcttgcaggt gttgcagcag cttatacgac tgaaacaaac gtagtcggct
    29041 ttatcggcgg tgtaaaaggt gaagtaatcg atcgttttga tgctggattc aaagccggtg
    29101 ttgatgcagg tgcgaaagaa ttaggaaaag aaatcaaagt attgaatcaa tatgctggtg
    29161 acttctctgc tccagataaa ggacgttcaa ttgctcaagg tatgtatgca caaaacgcag
    29221 atatcatctt ccatgcttca ggcggtacag gtaacggtgt attccaagaa gcaaaatcat
    29281 tgaacgaatc aggcgacaaa aaagtttggg ttatcggtgt tgaccgcgac caatcagacg
    29341 aaggcgaata cacattaaac ggcgaaaaga aaaacttcac attgacatct acactgaaag
    29401 cagttggaac agtagtagaa gatttggcac aaaaatcagc ggacggtaaa ttccctggcg
    29461 gcgaacacac tgtttatgga ttgaaagaag acggtgttgg tctaacagaa ggacaacttt
    29521 ctgacgaagc gaaaaaagca gttgatgaag caaaagaaaa aatcatttca ggtgacgtaa
    29581 aagttccaga aactcctgaa gaaaactaaa accatttcta tagccttgtt agacacatgt
    29641 ttgacaaggc tatggtttga ttagaacaag aattgttcat ttatccaagc tgccttgtga
    29701 cagtttggat aagggaacaa ctccctgaag taatgtttgt ttcaaaagaa gaacgctcac
    29761 taagcgtgaa tcttagtcaa tcgttgccct agatagaaat cgttaggatg tgaaaaaaag
    29821 gtggttcaag aaaatattgt catagaaatg cagaatatta ccaaagaatt tggaacattc
    29881 aaggcaaatg acaacatcaa tttacaagta aaggcaggag aaattcatgc gttgcttgga
    29941 gaaaacggtg ctggcaaatc tacattgatg aacgtgcttt ccggattatt agagccgaca
    30001 tcagggaaaa ttttgatgcg tgggaaagaa gtaaagatca caagtccgac caaagccaac
    30061 caattaggga ttgggatggt ccatcagcac tttatgcttg ttgatgcctt tactgtaaca
    30121 gaaaacatcg tgttgggaag cgagcctagt cgcgcaggga tgcttgacca taaaaaagca
    30181 cgaaaagaga tccaaaaagt ttctgaacag tatggattgt cagtcaaccc agatgcttac
    30241 gttcgtgata tttcagttgg aatggaacaa cgggtagaaa ttttaaaaac actttaccga
    30301 ggagcagatg tactgatttt tgatgagccg acagctgtat tgacccctca agaaattgat
    30361 gaattaatcg tgatcatgaa ggaattagtc aaagaaggca agtcgatcat tttgattacg
    30421 cataagttag atgaaatcaa agcagtagct gaccgctgta cagttatccg ccgtggaaaa
    30481 ggaatcggta cagtcaacgt taaagacgta acctcacaac aattagccga tatgatggtt
    30541 ggaagaacgg tttcattcaa aacgatgaaa aaagaagcga agcctcaaga agtcgttttg
    30601 tctattgaaa atctagtggt gaaagaaaat cgtggattag aagccgtgaa aaacttgaac
    30661 ttagaggttc gtgctggcga agtacttggt atcgctggaa tcgatggaaa cgggcagtcg
    30721 gagttgatcc aagctttgac tggtttgcga aaggcagaaa gcggacatat caagctaaaa
    30781 ggggaagaca tca
//
LOCUS       DAFBSV010000211         9675 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.guided.097, whole genome shotgun sequence.
ACCESSION   DAFBSV010000211 DAFBSV010000000
VERSION     DAFBSV010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9675
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.guided.097"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            98..793
                     /gene="vanR"
                     /locus_tag="LLB18_002859"
     CDS             98..793
                     /gene="vanR"
                     /locus_tag="LLB18_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBK5245784.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            771..1925
                     /locus_tag="LLB18_002860"
     CDS             771..1925
                     /locus_tag="LLB18_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBK5245785.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            2140..3108
                     /locus_tag="LLB18_002861"
     CDS             2140..3108
                     /locus_tag="LLB18_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HBK5245786.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            3101..4132
                     /gene="vanA"
                     /locus_tag="LLB18_002862"
     CDS             3101..4132
                     /gene="vanA"
                     /locus_tag="LLB18_002862"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HBK5245787.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            4138..4746
                     /locus_tag="LLB18_002863"
     CDS             4138..4746
                     /locus_tag="LLB18_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HBK5245788.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            5174..6085
                     /gene="vanY"
                     /locus_tag="LLB18_002864"
     CDS             5174..6085
                     /gene="vanY"
                     /locus_tag="LLB18_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HBK5245789.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            6238..6723
                     /gene="vanZ"
                     /locus_tag="LLB18_002865"
     CDS             6238..6723
                     /gene="vanZ"
                     /locus_tag="LLB18_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HBK5245790.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(7010..7339)
                     /locus_tag="LLB18_002866"
     CDS             complement(7010..7339)
                     /locus_tag="LLB18_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5245791.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            7644..7973
                     /locus_tag="LLB18_002867"
     CDS             7644..7973
                     /locus_tag="LLB18_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBK5245792.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            7963..8250
                     /locus_tag="LLB18_002868"
     CDS             7963..8250
                     /locus_tag="LLB18_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBK5245793.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(8529..9092)
                     /locus_tag="LLB18_002869"
     CDS             complement(8529..9092)
                     /locus_tag="LLB18_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBK5245794.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
BASE COUNT         3185 a         1658 c         1963 g         2869 t
ORIGIN      
        1 gggattttat tctttattta aaactttgca acagaaccat tcggccctat aatctgataa
       61 attattaagg gcaaacttat gtgaaagggt gataactatg agcgataaaa tacttattgt
      121 ggatgatgaa catgaaattg ccgatttggt tgaattatac ttaaaaaacg agaattatac
      181 ggttttcaaa tactataccg ccaaagaagc attggaatgt atagacaagt ctgagattga
      241 ccttgccata ttggacatca tgcttcccgg cacaagcggc cttactatct gtcaaaaaat
      301 aagggacaag cacacctatc cgattatcat gctgaccggg aaagatacag aggtagataa
      361 aattacaggg ttaacaatcg gcgcggatga ttatataacg aagccctttc gcccactgga
      421 gttaattgct cgggtaaagg cccagttgcg ccgatacaaa aaattcagtg gagtaaagga
      481 gcagaacgaa aatgttatcg tccactccgg ccttgtcatt aatgttaaca cccatgagtg
      541 ttatctgaac gagaagcagt tatcccttac tcccaccgag ttttcaatac tgcgaatcct
      601 ctgtgaaaac aaggggaatg tggttagctc cgagctgcta tttcatgaga tatggggcga
      661 cgaatatttc agcaagagca acaacaccat caccgtgcat atccggcatt tgcgcgaaaa
      721 aatgaacgac accattgata atccgaaata tataaaaacg gtatgggggg ttggttataa
      781 aattgaaaaa taaaaaaaac gactattcca aactagaacg aaaactttac atgtatatcg
      841 ttgcaattgt tgtggtagca attgtattcg tgttgtatat tcgttcaatg atccgaggga
      901 aacttgggga ttggatctta agtattttgg aaaacaaata tgacttaaat cacctggacg
      961 cgatgaaatt atatcaatat tccatacgga acaatataga tatctttatt tatgtggcga
     1021 ttgtcattag tattcttatt ctatgtcgcg tcatgctttc aaaattcgca aaatactttg
     1081 acgagataaa taccggcatt gatgtactta ttcagaacga agataaacaa attgagcttt
     1141 ctgcggaaat ggatgttatg gaacaaaagc tcaacacatt aaaacggact ctggaaaagc
     1201 gagagcagga tgcaaagctg gccgaacaaa gaaaaaatga cgttgttatg tacttggcgc
     1261 acgatattaa aacgcccctt acatccatta tcggttattt gagcctgctt gacgaggctc
     1321 cagacatgcc ggtagatcaa aaggcaaagt atgtgcatat cacgttggac aaagcgtatc
     1381 gactcgaaca gctaatcgac gagttttttg agattacacg gtataaccta caaacgataa
     1441 cgctaacaaa aacgcacata gacctatact atatgctggt gcagatgacc gatgaatttt
     1501 atcctcagct ttccgcacat ggaaaacagg cggttattca cgcccccgag gatctgaccg
     1561 tgtccggcga ccctgataaa ctcgcgagag tctttaacaa cattttgaaa aacgccgctg
     1621 catacagtga ggataacagc atcattgaca ttaccgcggg cctctccggg gatgtggtgt
     1681 caatcgaatt caagaacact ggaagcatcc caaaagataa gctagctgcc atatttgaaa
     1741 agttctatag gctggacaat gctcgttctt ccgatacggg tggcgcggga cttggattgg
     1801 cgattgcaaa agaaattatt gttcagcatg gagggcagat ttacgcggaa agcaatgata
     1861 actatacgac gtttagggta gagcttccag cgatgccaga cttggttgat aaaaggaggt
     1921 cctaagagat gtatataatt ttttaggaaa atctcaaggt tatctttact ttttcttagg
     1981 aaattaacaa tttaatatta agaaacggct cgttcttaca cggtagactt aataccgtaa
     2041 gaacgagccg ttttcgttct tcagagaaag atttgacaag attaccattg gcatccccgt
     2101 tttatttggt gcctttcaca gaaagggttg gtcttaatta tgaataacat cggcattact
     2161 gtttatggat gtgagcagga tgaggcagat gcattccatg ctctttcgcc tcgctttggc
     2221 gttatggcaa cgataattaa cgccaacgtg tcggaatcca acgccaaatc cgcgcctttc
     2281 aatcaatgta tcagtgtggg acataaatca gagatttccg cctctattct tcttgcgctg
     2341 aagagagccg gtgtgaaata tatttctacc cgaagcatcg gctgcaatca tatagataca
     2401 actgctgcta agagaatggg catcactgtc gacaatgtgg cgtactcgcc ggatagcgtt
     2461 gccgattata ctatgatgct aattcttatg gcagtacgca acgtaaaatc gattgtgcgc
     2521 tctgtggaaa aacatgattt caggttggac agcgaccgtg gcaaggtact cagcgacatg
     2581 acagttggtg tggtgggaac gggccagata ggcaaagcgg ttattgagcg gctgcgagga
     2641 tttggatgta aagtgttggc ttatagtcgc agccgaagta tagaggtaaa ctatgtaccg
     2701 tttgatgagt tgctgcaaaa tagcgatatc gttacgcttc atgtgccgct caatacggat
     2761 acgcactata ttatcagcca cgaacaaata cagagaatga agcaaggagc atttcttatc
     2821 aatactgggc gcggtccact tgtagatacc tatgagttgg ttaaagcatt agaaaacggg
     2881 aaactgggcg gtgccgcatt ggatgtattg gaaggagagg aagagttttt ctactctgat
     2941 tgcacccaaa aaccaattga taatcaattt ttacttaaac ttcaaagaat gcctaacgtg
     3001 ataatcacac cgcatacggc ctattatacc gagcaagcgt tgcgtgatac cgttgaaaaa
     3061 accattaaaa actgtttgga ttttgaaagg agacaggagc atgaatagaa taaaagttgc
     3121 aatactgttt gggggttgct cagaggagca tgacgtatcg gtaaaatctg caatagagat
     3181 agccgctaac attaataaag aaaaatacga gccgttatac attggaatta cgaaatctgg
     3241 tgtatggaaa atgtgcgaaa aaccttgcgc ggaatgggaa aacgacaatt gctattcagc
     3301 tgtactctcg ccggataaaa aaatgcacgg attacttgtt aaaaagaacc atgaatatga
     3361 aatcaaccat gttgatgtag cattttcagc tttgcatggc aagtcaggtg aagatggatc
     3421 catacaaggt ctgtttgaat tgtccggtat cccttttgta ggctgcgata ttcaaagctc
     3481 agcaatttgt atggacaaat cgttgacata catcgttgcg aaaaatgctg ggatagctac
     3541 tcccgccttt tgggttatta ataaagatga taggccggtg gcagctacgt ttacctatcc
     3601 tgtttttgtt aagccggcgc gttcaggctc atccttcggt gtgaaaaaag tcaatagcgc
     3661 ggacgaattg gactacgcaa ttgaatcggc aagacaatat gacagcaaaa tcttaattga
     3721 gcaggctgtt tcgggctgtg aggtcggttg tgcggtattg ggaaacagtg ccgcgttagc
     3781 tgttggcgag gtggaccaaa tcaggctgca gtacggaatc tttcgtattc atcaggaagt
     3841 cgagccggaa aaaggctctg aaaacgcagt tataaccgtt cccgcagacc tttcagcaga
     3901 ggagcgagga cggatacagg aaacggcaaa aaaaatatat aaagcgctcg gctgtagagg
     3961 tctagcccgt gtggatatgt ttttacaaga taacggccgc attgtactga acgaagtcaa
     4021 tactctgccc ggtttcacgt catacagtcg ttatccccgt atgatggccg ctgcaggtat
     4081 tgcacttccc gaactgattg accgcttgat cgtattagcg ttaaaggggt gataagcatg
     4141 gaaataggat ttactttttt agatgaaata gtacacggtg ttcgttggga cgctaaatat
     4201 gccacttggg ataatttcac cggaaaaccg gttgacggtt atgaagtaaa tcgcattgta
     4261 gggacatacg agttggctga atcgcttttg aaggcaaaag aactggctgc tacccaaggg
     4321 tacggattgc ttctatggga cggttaccgt cctaatcgtg ctgtaaactg ttttatgcaa
     4381 tgggctgcac agccggaaaa taacctgaca aaggaaagtt attatcccaa tattgaccga
     4441 actgagatga tttcaaaagg atacgtggct tcaaaatcaa gccatagccg cggcagtgcc
     4501 attgatctta cgctttatcg attagacacg ggtgagcttg taccaatggg gagccgattt
     4561 gattttatgg atgaacgctc tcatcatgcg gcaaatggaa tatcatgcaa tgaagcgcaa
     4621 aatcgcagac gtttgcgctc catcatggaa aacagtgggt ttgaagcata tagcctcgaa
     4681 tggtggcact atgtattaag agacgaacca taccccaata gctattttga tttccccgtt
     4741 aaataaactt ttaaccgttg cacggacaaa ctatataagc taactctttc ggcaggaaac
     4801 ccgacgtatg taactggttc ttagggaatt tatatatagt agatagtatt gaagatgtaa
     4861 ggcagagcga tattgcggtc attatctgcg tgcgctgcgg caagatagcc tgataataag
     4921 actgatcgca tagaggggtg gtatttcaca ccgcccattg tcaacaggca gttcagcctc
     4981 gttaaattca gcatgggtat cacttatgaa aattcatcta cattggtgat aatagtaaat
     5041 ccagtagggc gaaataattg actgtaattt acggggcaaa acggcacaat ctcaaacgag
     5101 attgtgccgt ttaaggggaa gattctagaa atatttcata cttccaacta tatagttaag
     5161 gaggagactg aaaatgaaga agttgttttt tttattgtta ttgttattct taatatactt
     5221 aggttatgac tacgttaatg aagcactgtt ttctcaggaa aaagtcgaat ttcaaaatta
     5281 tgatcaaaat cccaaagaac atttagaaaa tagtgggact tctgaaaata cccaagagaa
     5341 aacaattaca gaagaacagg tttatcaagg aaatctgcta ttaatcaata gtaaatatcc
     5401 tgttcgccaa gaaagtgtga agtcagatat cgtgaattta tctaaacatg acgaattaat
     5461 aaatggatac gggttgcttg atagtaatat ttatatgtca aaagaaatag cacaaaaatt
     5521 ttcagagatg gtcaatgatg ctgtaaaggg tggcgttagt cattttatta ttaatagtgg
     5581 ctatcgagac tttgatgagc aaagtgtgct ttaccaagaa atgggggctg agtatgcctt
     5641 accagcaggt tatagtgagc ataattcagg tttatcacta gatgtaggat caagcttgac
     5701 gaaaatggaa cgagcccctg aaggaaagtg gatagaagaa aatgcttgga aatacgggtt
     5761 cattttacgt tatccagagg acaaaacaga gttaacagga attcaatatg aactatggca
     5821 tattcgctat gttggtttac cacatagtgc gattatgaaa gaaaagaatt tcgttctcga
     5881 ggaatatatg gattacctaa aagaagaaaa aaccatttct gttagtgtaa atggggaaaa
     5941 atatgagatc ttttattatc ctgttactaa aaataccacc attcatgtgc cgactaatct
     6001 tcgttatgag atatcaggaa acaatataga cggtgtaatt gtgacagtgt ttcccggatc
     6061 aacacatact aattcaagga ggtaaggatg gcggaatgaa accaacgaaa ttaatgaaca
     6121 gcattattgt actagcactt ttggggtaac gttagctttt taatttaaaa cccacgttaa
     6181 ctaggacatt gctatactaa tgatacaact taaacaaaag aattagagga aattatattg
     6241 ggaaaaatat tatctagagg attgctagct ttatatttag tgacactaat ctggttagtg
     6301 ttattcaaat tacaatacaa tattttatca gtatttaatt atcatcaaag aagtcttaac
     6361 ttgactccat ttactgctac tgggaatttc agagagatga tagataatgt tataatcttt
     6421 attccatttg gcttgctttt gaatgtcaat tttaaagaaa tcggattttt acctaagttt
     6481 gcttttgtac tggttttaag tcttactttt gaaataattc aatttatctt cgctattgga
     6541 gcgacagaca taacagatgt aattacaaat actgttggag gctttcttgg actgaaatta
     6601 tatggtttaa gcaataagca tatgaatcaa aaaaaattag acagagttat tatttttgta
     6661 ggtatacttt tgctcgtatt attgctcgtt taccgtaccc atttaagaat aaattacgtg
     6721 taagatgtct aaatcaagca atctgatctt tcatacacat aaagatattg aatgaattgg
     6781 attagatgga aaacgggatg tggggaaact cgcccgtagg tgtgaagtga ggggaaaacc
     6841 ggtgataaag taaaaagctt acctaacact atagtaacaa agaaagccca attatcaatt
     6901 ttagtgctga ggaattggtc tctttaataa atttccttaa cgttgtaaat ccgcattttc
     6961 ctgacggtac ccccaaacta agatttcata gatagatttt ctgataactt taaaaaacac
     7021 gaatagcgga aaggatgtct tcattcgcta aagagtaata aactactttt ccatcttgac
     7081 gtgattttgc cattccatgt ttttttaaaa aacgtaaatg gtgtgacgtt gtagcgacac
     7141 tagcagtaag tatttctgct aaatcacaga cgcacatttc cttataggtt tctaaagcat
     7201 agaaaatttt aattctagaa aaatcgctga aacatttccc taacacaagt aagtttgaaa
     7261 aatctttttg atccaattta ttttttattc catttacttt ttctttatgt acgacagtca
     7321 cttggcaaac ttttttcatt catctcacct cacattcaaa cgattatttg aatgaagtat
     7381 acctatttga tcactctttt gtcaatctac cttaattcca atacactatt ataagcaatt
     7441 tcatgtattg aagtaaactt acttgcaagt gcgtttttga ttccaagtta aaaacatatt
     7501 attattctac ataatttcct aatcaaataa aactcctttg aaaattgttc taaaggagtt
     7561 ttattatttt gtatttctac taaaaatagc gtacaatgta attactaagt aattacgaaa
     7621 tgtaaaataa tggaggaaat aatatgatta caaaaacaag aaaacaagga aattctatta
     7681 tgttaacggt ccctaaagaa ttcgatgtgc ccaatggtgt tgaagtagaa gctaagcttg
     7741 tagagaatgg tatcctttat gagtttgtag agcctaaaaa agaatttttt gattttagtg
     7801 aagatatttt ggctgatatt ctttcagaag gttatagcaa acaagagatc ttaaaagaat
     7861 ttagaaatag aaaaaatgcg ttaacttctg catttaaatc tattgctgaa gatactgttg
     7921 caaattctaa accgatgaca aaagaggagt tggcagcaga aattggctta tgagattcta
     7981 ccttctaaac acgtaataaa gtatctaaaa aaattaaaag agaaaacatt aaaagaacaa
     8041 tttttaacga taatttatga tgagatagca gttcgtcctc attcgggaga acaaaaaacg
     8101 ggtgatttat caggaatttg ggctattgga ttcaagtatg caggtacgac atatcgcgtt
     8161 gcatatgaaa ttaaagataa tgcagtgata cctatcttac tatgtggaac gcatgaaaat
     8221 ttttatgaac aattaaaaaa gattaggtaa gaacccaatg tttcaacttg agaggataga
     8281 cgacacttta aaagataatt tttaacagct gagagttgta ataccctata attttaaacc
     8341 actaacctat atatttatga aaaatagaaa aaattaaaac gcattttaag cctctttcaa
     8401 attaaaagct tcatccttat gcacaaagag ggcttaaaat gcgttatttt atattgtttt
     8461 ttagtaataa taaaaaaatc actctaattc tcccataaat attatagatt cctaaagatt
     8521 aaaatagatt attccctatt gtcttttaag tagcggtaga gtgttgcctt gctaatacca
     8581 gtcatttccg taatttcttt tacgctataa acctgacttt tatacaattt tactgctcga
     8641 tcaacatctt tctggttcac tcgtggacgg ccacctttac gacctctcgc acgtgcactt
     8701 ttcaaacctt ctttggtacg ttcaacaatt aaatcacgtt cgaactgact aaatgcttgg
     8761 aagacagtca tcattaagcg tccgtgaggc gtgctggtat cgaagttttc tttcaagctc
     8821 accagcttaa catggtgttc ttcaaaatag gtaacaaggt caatcaaatc ctttgtacta
     8881 cgacccaatc gagaaaaact ttctacaatt accgtatctc ccggacgaat tttatctttt
     8941 aaacgattta gttggggacg aaccgctttg gttcccgtca ttttctcagt taggatttca
     9001 ttacaatttt gttcattgag taagtctaat tgacgattta gttcttgtga acgtgtactc
     9061 actcgggcat aaccataaat gtatccactc atgcttttct tcctttcgta ctttaattct
     9121 ggcttgattg tatcataaaa gggagttata gatacatagt taatgcaaca agttatgata
     9181 caaaatatga cctcttttat ttaataaaag aggtcatttc attttgtctc ataatcgatt
     9241 gtttttgata cgagtgtgta tacgaaataa acaaaaaaat cttaagtaaa tttctagata
     9301 cctaatttaa tcctaactag tgtatcctaa agttaataac gagtttatca caatgaaaat
     9361 tataaaatgc tcccatatta gatataacat gcaatatttg aattagaact acaaaattta
     9421 ttcgttttat aaagtaaata atgttgagat actaaggaat agaatattat aaggaattga
     9481 gctgaatgta ttggataaaa aaagaataac tttattagag atggactata aaaatgctcg
     9541 taattttctt ctgaagtctg aaagctattt gaatgctcag ctaccagaat atattagttt
     9601 tgacgaaact ttaaaatctg ctaaaaaagt tttaacttcg ccgtttgtat aattaagcga
     9661 gacaaataaa aaagc
//
LOCUS       DAFBSV010000212         9674 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.guided.098, whole genome shotgun sequence.
ACCESSION   DAFBSV010000212 DAFBSV010000000
VERSION     DAFBSV010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9674
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.guided.098"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            98..793
                     /gene="vanR"
                     /locus_tag="LLB18_002870"
     CDS             98..793
                     /gene="vanR"
                     /locus_tag="LLB18_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBK5245795.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            771..1925
                     /locus_tag="LLB18_002871"
     CDS             771..1925
                     /locus_tag="LLB18_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBK5245796.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            2140..3108
                     /locus_tag="LLB18_002872"
     CDS             2140..3108
                     /locus_tag="LLB18_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HBK5245797.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            3101..4132
                     /gene="vanA"
                     /locus_tag="LLB18_002873"
     CDS             3101..4132
                     /gene="vanA"
                     /locus_tag="LLB18_002873"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HBK5245798.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            4138..4746
                     /locus_tag="LLB18_002874"
     CDS             4138..4746
                     /locus_tag="LLB18_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HBK5245799.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            5174..6085
                     /gene="vanY"
                     /locus_tag="LLB18_002875"
     CDS             5174..6085
                     /gene="vanY"
                     /locus_tag="LLB18_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HBK5245800.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            6238..6722
                     /gene="vanZ"
                     /locus_tag="LLB18_002876"
                     /pseudo
     CDS             6238..6722
                     /gene="vanZ"
                     /locus_tag="LLB18_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
     gene            complement(7009..7338)
                     /locus_tag="LLB18_002877"
     CDS             complement(7009..7338)
                     /locus_tag="LLB18_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5245801.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            7643..7972
                     /locus_tag="LLB18_002878"
     CDS             7643..7972
                     /locus_tag="LLB18_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBK5245802.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            7962..8249
                     /locus_tag="LLB18_002879"
     CDS             7962..8249
                     /locus_tag="LLB18_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBK5245803.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(8528..9091)
                     /locus_tag="LLB18_002880"
     CDS             complement(8528..9091)
                     /locus_tag="LLB18_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBK5245804.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
BASE COUNT         3184 a         1658 c         1963 g         2869 t
ORIGIN      
        1 gggattttat tctttattta aaactttgca acagaaccat tcggccctat aatctgataa
       61 attattaagg gcaaacttat gtgaaagggt gataactatg agcgataaaa tacttattgt
      121 ggatgatgaa catgaaattg ccgatttggt tgaattatac ttaaaaaacg agaattatac
      181 ggttttcaaa tactataccg ccaaagaagc attggaatgt atagacaagt ctgagattga
      241 ccttgccata ttggacatca tgcttcccgg cacaagcggc cttactatct gtcaaaaaat
      301 aagggacaag cacacctatc cgattatcat gctgaccggg aaagatacag aggtagataa
      361 aattacaggg ttaacaatcg gcgcggatga ttatataacg aagccctttc gcccactgga
      421 gttaattgct cgggtaaagg cccagttgcg ccgatacaaa aaattcagtg gagtaaagga
      481 gcagaacgaa aatgttatcg tccactccgg ccttgtcatt aatgttaaca cccatgagtg
      541 ttatctgaac gagaagcagt tatcccttac tcccaccgag ttttcaatac tgcgaatcct
      601 ctgtgaaaac aaggggaatg tggttagctc cgagctgcta tttcatgaga tatggggcga
      661 cgaatatttc agcaagagca acaacaccat caccgtgcat atccggcatt tgcgcgaaaa
      721 aatgaacgac accattgata atccgaaata tataaaaacg gtatgggggg ttggttataa
      781 aattgaaaaa taaaaaaaac gactattcca aactagaacg aaaactttac atgtatatcg
      841 ttgcaattgt tgtggtagca attgtattcg tgttgtatat tcgttcaatg atccgaggga
      901 aacttgggga ttggatctta agtattttgg aaaacaaata tgacttaaat cacctggacg
      961 cgatgaaatt atatcaatat tccatacgga acaatataga tatctttatt tatgtggcga
     1021 ttgtcattag tattcttatt ctatgtcgcg tcatgctttc aaaattcgca aaatactttg
     1081 acgagataaa taccggcatt gatgtactta ttcagaacga agataaacaa attgagcttt
     1141 ctgcggaaat ggatgttatg gaacaaaagc tcaacacatt aaaacggact ctggaaaagc
     1201 gagagcagga tgcaaagctg gccgaacaaa gaaaaaatga cgttgttatg tacttggcgc
     1261 acgatattaa aacgcccctt acatccatta tcggttattt gagcctgctt gacgaggctc
     1321 cagacatgcc ggtagatcaa aaggcaaagt atgtgcatat cacgttggac aaagcgtatc
     1381 gactcgaaca gctaatcgac gagttttttg agattacacg gtataaccta caaacgataa
     1441 cgctaacaaa aacgcacata gacctatact atatgctggt gcagatgacc gatgaatttt
     1501 atcctcagct ttccgcacat ggaaaacagg cggttattca cgcccccgag gatctgaccg
     1561 tgtccggcga ccctgataaa ctcgcgagag tctttaacaa cattttgaaa aacgccgctg
     1621 catacagtga ggataacagc atcattgaca ttaccgcggg cctctccggg gatgtggtgt
     1681 caatcgaatt caagaacact ggaagcatcc caaaagataa gctagctgcc atatttgaaa
     1741 agttctatag gctggacaat gctcgttctt ccgatacggg tggcgcggga cttggattgg
     1801 cgattgcaaa agaaattatt gttcagcatg gagggcagat ttacgcggaa agcaatgata
     1861 actatacgac gtttagggta gagcttccag cgatgccaga cttggttgat aaaaggaggt
     1921 cctaagagat gtatataatt ttttaggaaa atctcaaggt tatctttact ttttcttagg
     1981 aaattaacaa tttaatatta agaaacggct cgttcttaca cggtagactt aataccgtaa
     2041 gaacgagccg ttttcgttct tcagagaaag atttgacaag attaccattg gcatccccgt
     2101 tttatttggt gcctttcaca gaaagggttg gtcttaatta tgaataacat cggcattact
     2161 gtttatggat gtgagcagga tgaggcagat gcattccatg ctctttcgcc tcgctttggc
     2221 gttatggcaa cgataattaa cgccaacgtg tcggaatcca acgccaaatc cgcgcctttc
     2281 aatcaatgta tcagtgtggg acataaatca gagatttccg cctctattct tcttgcgctg
     2341 aagagagccg gtgtgaaata tatttctacc cgaagcatcg gctgcaatca tatagataca
     2401 actgctgcta agagaatggg catcactgtc gacaatgtgg cgtactcgcc ggatagcgtt
     2461 gccgattata ctatgatgct aattcttatg gcagtacgca acgtaaaatc gattgtgcgc
     2521 tctgtggaaa aacatgattt caggttggac agcgaccgtg gcaaggtact cagcgacatg
     2581 acagttggtg tggtgggaac gggccagata ggcaaagcgg ttattgagcg gctgcgagga
     2641 tttggatgta aagtgttggc ttatagtcgc agccgaagta tagaggtaaa ctatgtaccg
     2701 tttgatgagt tgctgcaaaa tagcgatatc gttacgcttc atgtgccgct caatacggat
     2761 acgcactata ttatcagcca cgaacaaata cagagaatga agcaaggagc atttcttatc
     2821 aatactgggc gcggtccact tgtagatacc tatgagttgg ttaaagcatt agaaaacggg
     2881 aaactgggcg gtgccgcatt ggatgtattg gaaggagagg aagagttttt ctactctgat
     2941 tgcacccaaa aaccaattga taatcaattt ttacttaaac ttcaaagaat gcctaacgtg
     3001 ataatcacac cgcatacggc ctattatacc gagcaagcgt tgcgtgatac cgttgaaaaa
     3061 accattaaaa actgtttgga ttttgaaagg agacaggagc atgaatagaa taaaagttgc
     3121 aatactgttt gggggttgct cagaggagca tgacgtatcg gtaaaatctg caatagagat
     3181 agccgctaac attaataaag aaaaatacga gccgttatac attggaatta cgaaatctgg
     3241 tgtatggaaa atgtgcgaaa aaccttgcgc ggaatgggaa aacgacaatt gctattcagc
     3301 tgtactctcg ccggataaaa aaatgcacgg attacttgtt aaaaagaacc atgaatatga
     3361 aatcaaccat gttgatgtag cattttcagc tttgcatggc aagtcaggtg aagatggatc
     3421 catacaaggt ctgtttgaat tgtccggtat cccttttgta ggctgcgata ttcaaagctc
     3481 agcaatttgt atggacaaat cgttgacata catcgttgcg aaaaatgctg ggatagctac
     3541 tcccgccttt tgggttatta ataaagatga taggccggtg gcagctacgt ttacctatcc
     3601 tgtttttgtt aagccggcgc gttcaggctc atccttcggt gtgaaaaaag tcaatagcgc
     3661 ggacgaattg gactacgcaa ttgaatcggc aagacaatat gacagcaaaa tcttaattga
     3721 gcaggctgtt tcgggctgtg aggtcggttg tgcggtattg ggaaacagtg ccgcgttagc
     3781 tgttggcgag gtggaccaaa tcaggctgca gtacggaatc tttcgtattc atcaggaagt
     3841 cgagccggaa aaaggctctg aaaacgcagt tataaccgtt cccgcagacc tttcagcaga
     3901 ggagcgagga cggatacagg aaacggcaaa aaaaatatat aaagcgctcg gctgtagagg
     3961 tctagcccgt gtggatatgt ttttacaaga taacggccgc attgtactga acgaagtcaa
     4021 tactctgccc ggtttcacgt catacagtcg ttatccccgt atgatggccg ctgcaggtat
     4081 tgcacttccc gaactgattg accgcttgat cgtattagcg ttaaaggggt gataagcatg
     4141 gaaataggat ttactttttt agatgaaata gtacacggtg ttcgttggga cgctaaatat
     4201 gccacttggg ataatttcac cggaaaaccg gttgacggtt atgaagtaaa tcgcattgta
     4261 gggacatacg agttggctga atcgcttttg aaggcaaaag aactggctgc tacccaaggg
     4321 tacggattgc ttctatggga cggttaccgt cctaatcgtg ctgtaaactg ttttatgcaa
     4381 tgggctgcac agccggaaaa taacctgaca aaggaaagtt attatcccaa tattgaccga
     4441 actgagatga tttcaaaagg atacgtggct tcaaaatcaa gccatagccg cggcagtgcc
     4501 attgatctta cgctttatcg attagacacg ggtgagcttg taccaatggg gagccgattt
     4561 gattttatgg atgaacgctc tcatcatgcg gcaaatggaa tatcatgcaa tgaagcgcaa
     4621 aatcgcagac gtttgcgctc catcatggaa aacagtgggt ttgaagcata tagcctcgaa
     4681 tggtggcact atgtattaag agacgaacca taccccaata gctattttga tttccccgtt
     4741 aaataaactt ttaaccgttg cacggacaaa ctatataagc taactctttc ggcaggaaac
     4801 ccgacgtatg taactggttc ttagggaatt tatatatagt agatagtatt gaagatgtaa
     4861 ggcagagcga tattgcggtc attatctgcg tgcgctgcgg caagatagcc tgataataag
     4921 actgatcgca tagaggggtg gtatttcaca ccgcccattg tcaacaggca gttcagcctc
     4981 gttaaattca gcatgggtat cacttatgaa aattcatcta cattggtgat aatagtaaat
     5041 ccagtagggc gaaataattg actgtaattt acggggcaaa acggcacaat ctcaaacgag
     5101 attgtgccgt ttaaggggaa gattctagaa atatttcata cttccaacta tatagttaag
     5161 gaggagactg aaaatgaaga agttgttttt tttattgtta ttgttattct taatatactt
     5221 aggttatgac tacgttaatg aagcactgtt ttctcaggaa aaagtcgaat ttcaaaatta
     5281 tgatcaaaat cccaaagaac atttagaaaa tagtgggact tctgaaaata cccaagagaa
     5341 aacaattaca gaagaacagg tttatcaagg aaatctgcta ttaatcaata gtaaatatcc
     5401 tgttcgccaa gaaagtgtga agtcagatat cgtgaattta tctaaacatg acgaattaat
     5461 aaatggatac gggttgcttg atagtaatat ttatatgtca aaagaaatag cacaaaaatt
     5521 ttcagagatg gtcaatgatg ctgtaaaggg tggcgttagt cattttatta ttaatagtgg
     5581 ctatcgagac tttgatgagc aaagtgtgct ttaccaagaa atgggggctg agtatgcctt
     5641 accagcaggt tatagtgagc ataattcagg tttatcacta gatgtaggat caagcttgac
     5701 gaaaatggaa cgagcccctg aaggaaagtg gatagaagaa aatgcttgga aatacgggtt
     5761 cattttacgt tatccagagg acaaaacaga gttaacagga attcaatatg aactatggca
     5821 tattcgctat gttggtttac cacatagtgc gattatgaaa gaaaagaatt tcgttctcga
     5881 ggaatatatg gattacctaa aagaagaaaa aaccatttct gttagtgtaa atggggaaaa
     5941 atatgagatc ttttattatc ctgttactaa aaataccacc attcatgtgc cgactaatct
     6001 tcgttatgag atatcaggaa acaatataga cggtgtaatt gtgacagtgt ttcccggatc
     6061 aacacatact aattcaagga ggtaaggatg gcggaatgaa accaacgaaa ttaatgaaca
     6121 gcattattgt actagcactt ttggggtaac gttagctttt taatttaaaa cccacgttaa
     6181 ctaggacatt gctatactaa tgatacaact taaacaaaag aattagagga aattatattg
     6241 ggaaaaatat tatctagagg attgctagct ttatatttag tgacactaat ctggttagtg
     6301 ttattcaaat tacaatacaa tattttatca gtatttaatt atcatcaaag aagtcttaac
     6361 ttgactccat ttactgctac tgggaatttc agagagatga tagataatgt tataatcttt
     6421 attccatttg gcttgctttt gaatgtcaat tttaaagaaa tcggattttt acctaagttt
     6481 gcttttgtac tggttttaag tcttactttt gaaataattc aatttatctt cgctattgga
     6541 gcgacagaca taacagatgt aattacaaat actgttggag gctttcttgg actgaaatta
     6601 tatggtttaa gcaataagca tatgaatcaa aaaaattaga cagagttatt atttttgtag
     6661 gtatactttt gctcgtatta ttgctcgttt accgtaccca tttaagaata aattacgtgt
     6721 aagatgtcta aatcaagcaa tctgatcttt catacacata aagatattga atgaattgga
     6781 ttagatggaa aacgggatgt ggggaaactc gcccgtaggt gtgaagtgag gggaaaaccg
     6841 gtgataaagt aaaaagctta cctaacacta tagtaacaaa gaaagcccaa ttatcaattt
     6901 tagtgctgag gaattggtct ctttaataaa tttccttaac gttgtaaatc cgcattttcc
     6961 tgacggtacc cccaaactaa gatttcatag atagattttc tgataacttt aaaaaacacg
     7021 aatagcggaa aggatgtctt cattcgctaa agagtaataa actacttttc catcttgacg
     7081 tgattttgcc attccatgtt tttttaaaaa acgtaaatgg tgtgacgttg tagcgacact
     7141 agcagtaagt atttctgcta aatcacagac gcacatttcc ttataggttt ctaaagcata
     7201 gaaaatttta attctagaaa aatcgctgaa acatttccct aacacaagta agtttgaaaa
     7261 atctttttga tccaatttat tttttattcc atttactttt tctttatgta cgacagtcac
     7321 ttggcaaact tttttcattc atctcacctc acattcaaac gattatttga atgaagtata
     7381 cctatttgat cactcttttg tcaatctacc ttaattccaa tacactatta taagcaattt
     7441 catgtattga agtaaactta cttgcaagtg cgtttttgat tccaagttaa aaacatatta
     7501 ttattctaca taatttccta atcaaataaa actcctttga aaattgttct aaaggagttt
     7561 tattattttg tatttctact aaaaatagcg tacaatgtaa ttactaagta attacgaaat
     7621 gtaaaataat ggaggaaata atatgattac aaaaacaaga aaacaaggaa attctattat
     7681 gttaacggtc cctaaagaat tcgatgtgcc caatggtgtt gaagtagaag ctaagcttgt
     7741 agagaatggt atcctttatg agtttgtaga gcctaaaaaa gaattttttg attttagtga
     7801 agatattttg gctgatattc tttcagaagg ttatagcaaa caagagatct taaaagaatt
     7861 tagaaataga aaaaatgcgt taacttctgc atttaaatct attgctgaag atactgttgc
     7921 aaattctaaa ccgatgacaa aagaggagtt ggcagcagaa attggcttat gagattctac
     7981 cttctaaaca cgtaataaag tatctaaaaa aattaaaaga gaaaacatta aaagaacaat
     8041 ttttaacgat aatttatgat gagatagcag ttcgtcctca ttcgggagaa caaaaaacgg
     8101 gtgatttatc aggaatttgg gctattggat tcaagtatgc aggtacgaca tatcgcgttg
     8161 catatgaaat taaagataat gcagtgatac ctatcttact atgtggaacg catgaaaatt
     8221 tttatgaaca attaaaaaag attaggtaag aacccaatgt ttcaacttga gaggatagac
     8281 gacactttaa aagataattt ttaacagctg agagttgtaa taccctataa ttttaaacca
     8341 ctaacctata tatttatgaa aaatagaaaa aattaaaacg cattttaagc ctctttcaaa
     8401 ttaaaagctt catccttatg cacaaagagg gcttaaaatg cgttatttta tattgttttt
     8461 tagtaataat aaaaaaatca ctctaattct cccataaata ttatagattc ctaaagatta
     8521 aaatagatta ttccctattg tcttttaagt agcggtagag tgttgccttg ctaataccag
     8581 tcatttccgt aatttctttt acgctataaa cctgactttt atacaatttt actgctcgat
     8641 caacatcttt ctggttcact cgtggacggc cacctttacg acctctcgca cgtgcacttt
     8701 tcaaaccttc tttggtacgt tcaacaatta aatcacgttc gaactgacta aatgcttgga
     8761 agacagtcat cattaagcgt ccgtgaggcg tgctggtatc gaagttttct ttcaagctca
     8821 ccagcttaac atggtgttct tcaaaatagg taacaaggtc aatcaaatcc tttgtactac
     8881 gacccaatcg agaaaaactt tctacaatta ccgtatctcc cggacgaatt ttatctttta
     8941 aacgatttag ttggggacga accgctttgg ttcccgtcat tttctcagtt aggatttcat
     9001 tacaattttg ttcattgagt aagtctaatt gacgatttag ttcttgtgaa cgtgtactca
     9061 ctcgggcata accataaatg tatccactca tgcttttctt cctttcgtac tttaattctg
     9121 gcttgattgt atcataaaag ggagttatag atacatagtt aatgcaacaa gttatgatac
     9181 aaaatatgac ctcttttatt taataaaaga ggtcatttca ttttgtctca taatcgattg
     9241 tttttgatac gagtgtgtat acgaaataaa caaaaaaatc ttaagtaaat ttctagatac
     9301 ctaatttaat cctaactagt gtatcctaaa gttaataacg agtttatcac aatgaaaatt
     9361 ataaaatgct cccatattag atataacatg caatatttga attagaacta caaaatttat
     9421 tcgttttata aagtaaataa tgttgagata ctaaggaata gaatattata aggaattgag
     9481 ctgaatgtat tggataaaaa aagaataact ttattagaga tggactataa aaatgctcgt
     9541 aattttcttc tgaagtctga aagctatttg aatgctcagc taccagaata tattagtttt
     9601 gacgaaactt taaaatctgc taaaaaagtt ttaacttcgc cgtttgtata attaagcgag
     9661 acaaataaaa aagc
//
LOCUS       DAFBSV010000213         5985 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.guided.122, whole genome shotgun sequence.
ACCESSION   DAFBSV010000213 DAFBSV010000000
VERSION     DAFBSV010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5985
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.guided.122"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            154..819
                     /locus_tag="LLB18_002881"
                     /pseudo
     CDS             154..819
                     /locus_tag="LLB18_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            855..1100
                     /locus_tag="LLB18_002882"
     CDS             855..1100
                     /locus_tag="LLB18_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBK5245805.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            1203..2072
                     /locus_tag="LLB18_002883"
     CDS             1203..2072
                     /locus_tag="LLB18_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBK5245806.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            2053..2787
                     /locus_tag="LLB18_002884"
     CDS             2053..2787
                     /locus_tag="LLB18_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBK5245807.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            2820..3728
                     /locus_tag="LLB18_002885"
     CDS             2820..3728
                     /locus_tag="LLB18_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HBK5245808.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            3725..4267
                     /gene="sat4"
                     /locus_tag="LLB18_002886"
     CDS             3725..4267
                     /gene="sat4"
                     /locus_tag="LLB18_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HBK5245809.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            4360..5154
                     /locus_tag="LLB18_002887"
                     /note="aph(3')-IIIa"
     CDS             4360..5154
                     /locus_tag="LLB18_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HBK5245810.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            5430..5972
                     /locus_tag="LLB18_002888"
     CDS             5430..5972
                     /locus_tag="LLB18_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBK5245811.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIEPVLLQSFK"
BASE COUNT         2052 a          899 c         1311 g         1723 t
ORIGIN      
        1 caattctgat tcatcagtcc cataaattat agagcccttt ccatttagat agtagtggaa
       61 agacctctat ttatcttttg aaagtgaata caaaaataaa gcacactctg ctataatata
      121 ggtgattaat ccatttgaga gaggtgcttt atcatgtatc aaaattatac cataaaccaa
      181 ctttgtttgc ctatagatct tgaaattaaa ttagaagaaa atgattttgc tcatgccatt
      241 gtgcagtttg ttgactctat tcccgatgaa gtctttcttc cttattatca atctatgggt
      301 agaccccaat atcatcctcg tatgctactt tccattattc tttgtgccta tattcaaggg
      361 gtttattcgg gccgccaaat acaaaatatg ctgatagata gtattcggat gcgctactta
      421 tctcaagagc aattccctaa ctttcgtact attaatcgtt ttcgcgttca tccgattatg
      481 aacgatattc tagatcattc atttgttcaa tttcgtgagc tactggttca aagtggctta
      541 atcagtggca gtgctctata cattgatggt acaaaaattg aagcggatgc gaataaatac
      601 tctttcgttt ggaaaaaaag tattttaaag tataaggata gccttgatca aaaagccctt
      661 gaaaactacc aacaaatggt ggaaacaaaa atcttacctg agttaataga tgatttaaag
      721 gatgaacttt ctatagaaga gattgaaagg attcgtcaat ctttggaaga aaaggaaaat
      781 caattaattg aagcgattga ccaaaccgaa acagtagaag ggggctgacc cattattaat
      841 aaggagtgga caacatgatt gatgtaaatg agctattgga agaagctatt agagaaactg
      901 aaaatctaaa tgatggcgaa gtttttcttg ttaaagattt attcaaggga tatgtgggga
      961 ataggatacc cagaaaggat cgacttctgc ttggaacgtt atttttaaac catgttagca
     1021 aaatgaatgg taatttaaag gctattgaaa agacttcatc taatcagcag aggtataaaa
     1081 agacaattga taagttttaa ctatcttttg tgaaattaaa aaaattataa atatgttgag
     1141 tagaagcaaa agatttggct tggaattttt acagcagtga atcgataaaa ggagcatgct
     1201 tgatggtaga taatattatt aaatcagtag cagagaaatt atcctctctg tcttatatag
     1261 aaggtattgt tttaggtggt tcacgtgcaa ggggcaccca tacagaggat tcggatatag
     1321 atatcggcat ctattacaat tcagaatcat ttgacataaa tactattaat caattcgcta
     1381 caaagctgga tgatgagcat agaaataacc ttgttgtacc tcccggagca tggggtgatt
     1441 ggattaatgg cggcggatgg ttagtcataa acgggtatca tgtggattta attttacgtg
     1501 atattaaacg tgtggaacaa ataatgaaag atacagagca cggaattgtt actgccaatt
     1561 atcagactgg gcatccccat ggttatatta gtgcaatgta tcgaggagaa ttagcgatta
     1621 gcaaaatact atatgctaag aatgaaagct tatgcgaatt aaaaaaacag gcagaaactt
     1681 atcccaatgc tttgcagaaa agtttagtta acttttttat gtttgaagca gggttctctt
     1741 taatgtttgt aaaagcaaat tcgggaacag acgataaata ttatattgcg ggtcatgttt
     1801 ttcgtatagt ttcatgttta aatcaagtgt tatttgcatg taataatgct tattgtatca
     1861 acgaaaagaa agctataaaa ctgcttgaaa cttttgaaca taaacctgaa aaatataccg
     1921 agaaggtaaa tcatattttt gaagtactcg gtatctcact ttttgaatgc tacgacatga
     1981 ccgagaagct ttataatgaa gtgaatgaaa ttgtatcgga gataaataac tttttaaacg
     2041 aggagagttc agatgaaaga aaacaaatat gatgataata tattttttca aaaatacagt
     2101 caaatgagtc gctcgcagaa aggactggct ggtgcgggag aatgggagac tttgaaaaag
     2161 atgctacctg attttaaggg taagcgtgtg cttgatttag gatgcggcta tggatggcac
     2221 tgtatatatg cgatggaaaa cggtgcttcc tctgtagtag gtgttgatat ttctcataaa
     2281 atgctcgaag tagcaaaagg aaaaacccat tttccacaga ttgaatatga atgctgtgcc
     2341 atagaagatg tggatttccc agaggagagc tttgatgtaa tactaagttc gcttgcgttt
     2401 cattatgtag cagactatga gaatttaata aaaaagatat ataggatgct gaaggctggt
     2461 ggcaatttag tttttacagt tgaacatcct gtttttactg ctcatggaac acaagactgg
     2521 tattataacg aaaaaggaga aatactgcat ttcccggtgg acaattatta ttatgagggc
     2581 aaacggacag ctatgttttt ggaagaaaag gttacaaaat atcatagaac actgaccaca
     2641 tatctaaata cactgctttc aaatagtttt ataataaatc agattgtgga gccacagccg
     2701 ccagagaaca tgatggatat tccggggatg gcggatgaaa tgcgacgccc aatgatgctg
     2761 attgtatcgg caaaaaagaa gatgtaataa tatagaaaaa ataaacgagg agtatgtaaa
     2821 tgagatcaga aaaagaaatg atggatttag tactttcttt agcagaacag gatgaacgta
     2881 ttcgaattgt gacccttgag gggtcacgcg caaatattaa tatacctaaa gatgaatttc
     2941 aggattatga tattacatat tttgtaagtg atatagaacc gtttatatct aatgatgact
     3001 ggcttaatca atttgggaat ataataatga tgcaaaagcc ggaggatatg gaattattcc
     3061 cacctgaaga aaagggattt tcctatctta tgctatttga tgattacaat aaaattgatc
     3121 ttaccttatt gcccttggaa gagttagata attacctaaa gggcgataaa ttaataaagg
     3181 ttctaattga taaagattgt agaattaaaa gggacatagt tccgactgat atagattatc
     3241 atgtaagaaa gccaagcgca agggagtatg atgattgctg caatgaattt tggaatgtaa
     3301 caccttatgt tattaaagga ttgtgccgta aggaaatttt atttgctatt gatcatttta
     3361 atcagattgt tcgccatgag ctgctgagaa tgatatcatg gaaggtcggc atcgaaacag
     3421 gctttaaatt aagtgtaggc aagaactata agtttattga aaggtatata tccgaggatt
     3481 tgtgggagaa acttttgtcc acctaccgga tggattccta tgaaaacata tgggaagcat
     3541 tatttctatg ccatcaattg ttcagggcgg tatccggtga ggtggcggaa aggcttcatt
     3601 atgcctatcc ggagtatgat aggaatataa caaaatatac cagggacatg tataaaaaat
     3661 acactggtaa aaccggctgc ctggatagca catatgccgc tgatatagaa gagaggcggg
     3721 aacagtgatt acagaaatga aagcagggca cctgaaagat atcgataaac ccagcgaacc
     3781 atttgaggtg ataggtaaga ttataccgag gtatgaaaac gagaattgga cctttacaga
     3841 attactctat gaagcgccat atttaaaaag ctaccaagac gaagaggatg aagaggatga
     3901 ggaggcagat tgccttgaat atattgacaa tactgataag ataatatatc tttactacca
     3961 agacgataaa tgcgtcggaa aagttaaact gcgaaaaaat tggaaccggt acgcttatat
     4021 agaagatatc gccgtatgta aggatttcag ggggcaaggc ataggcagcg cgcttatcaa
     4081 tatatctata gaatgggcaa agcataaaaa cttgcatgga ctaatgcttg aaacccagga
     4141 caataacctt atagcttgta aattctatca taattgtggt ttcaaaatcg gctccgtcga
     4201 tactatgtta tacgccaact ttgaaaacaa ctttgaaaaa gctgttttct ggtatttaag
     4261 gttttagaat gcaaggaaca gtgaattgga gttcgtcttg ttataattag cttcttgggg
     4321 tatctttaaa tactgtagaa aagaggaagg aaataataaa tggctaaaat gagaatatca
     4381 ccggaattga aaaaactgat cgaaaaatac cgctgcgtaa aagatacgga aggaatgtct
     4441 cctgctaagg tatataagct ggtgggagaa aatgaaaacc tatatttaaa aatgacggac
     4501 agccggtata aagggaccac ctatgatgtg gaacgggaaa aggacatgat gctatggctg
     4561 gaaggaaagc tgcctgttcc aaaggtcctg cactttgaac ggcatgatgg ctggagcaat
     4621 ctgctcatga gtgaggccga tggcgtcctt tgctcggaag agtatgaaga tgaacaaagc
     4681 cctgaaaaga ttatcgagct gtatgcggag tgcatcaggc tctttcactc catcgacata
     4741 tcggattgtc cctatacgaa tagcttagac agccgcttag ccgaattgga ttacttactg
     4801 aataacgatc tggccgatgt ggattgcgaa aactgggaag aagacactcc atttaaagat
     4861 ccgcgcgagc tgtatgattt tttaaagacg gaaaagcccg aagaggaact tgtcttttcc
     4921 cacggcgacc tgggagacag caacatcttt gtgaaagatg gcaaagtaag tggctttatt
     4981 gatcttggga gaagcggcag ggcggacaag tggtatgaca ttgccttctg cgtccggtcg
     5041 atcagggagg atatcgggga agaacagtat gtcgagctat tttttgactt actggggatc
     5101 aagcctgatt gggagaaaat aaaatattat attttactgg atgaattgtt ttagtaccta
     5161 gatttagatg tctaaaaagc tttaactaca agctttttag acatctaatc ttttctgaag
     5221 tacatccgca actgtccata ctctgatgtt ttatatcttt tctaaaagtt cgctagatag
     5281 agttctatat tagagatgta aagagttttg gtgaagaggt ttgtgagtat ggcttttata
     5341 accagggtgc aatgagaagc actaacagca gctagcttaa gaacgcatag gatatacttt
     5401 ttatggaagt cacagaggag gaataaaatt tgaacaggat taacagagta acctctattc
     5461 ttattcagct gcaatcaaaa aaaataattc ctgccaaaga aattgcacag cgatttaata
     5521 taagcttaag gacagtttac agagatatcc ggacacttga agaagccgga ataccaattg
     5581 gatctgaggc cggaaaagga tattttcttg tagagggctt cctacttccg ccggtaatgt
     5641 ttacagcggc ggaagtgggt gcattgatta cagcagggaa atttttaaat tgccatggag
     5701 atgaatcatt tataaaggat tttgattcag ctatgtataa aatcaaatct attttgaagc
     5761 atggtgaaaa aaactatgca caggagttgg agaacagtat taacgtgtac agcacatctg
     5821 gacagaaaaa tacattggcg gataacgtta ttgcagcaat tcagactgca atctgcaata
     5881 aaagggtaat atcaattcaa tatcctgcat caggagggca agaaccggaa agcagaatga
     5941 tagagccggt tctgttgcaa agttttaaat aaagaataaa atccc
//
LOCUS       DAFBSV010000214         5882 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.guided.124, whole genome shotgun sequence.
ACCESSION   DAFBSV010000214 DAFBSV010000000
VERSION     DAFBSV010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5882
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.guided.124"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            401..865
                     /locus_tag="LLB18_002889"
     CDS             401..865
                     /locus_tag="LLB18_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK5245812.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            849..1478
                     /locus_tag="LLB18_002890"
     CDS             849..1478
                     /locus_tag="LLB18_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBK5245813.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            1832..3310
                     /gene="msr(C)"
                     /locus_tag="LLB18_002891"
     CDS             1832..3310
                     /gene="msr(C)"
                     /locus_tag="LLB18_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBK5245814.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            3357..3803
                     /locus_tag="LLB18_002892"
     CDS             3357..3803
                     /locus_tag="LLB18_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBK5245815.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(4002..4517)
                     /locus_tag="LLB18_002893"
     CDS             complement(4002..4517)
                     /locus_tag="LLB18_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBK5245816.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            4634..5836
                     /locus_tag="LLB18_002894"
     CDS             4634..5836
                     /locus_tag="LLB18_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5245817.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         1822 a          984 c         1242 g         1834 t
ORIGIN      
        1 atgctggtgt catccaccaa catcaaaaag tatagagcca aaaaaggttg tgacaacatc
       61 ttgtcataac ttttttatta ctgtttaagc atactgatcc aatttctaat attcgacggg
      121 attcttgcaa aaggcgattt cggaaatttt tggcggtgta aaattttcta ctgcagaaga
      181 gctatcttct atagtttgat aagaatcaat aatcttggtt ttagcgttgt gctttcttta
      241 tcattttttc cgttcattct acaaaaaatt tcttttctct atacttttct attgagagcg
      301 ttttttttat tacacagctg attctttgac ttttttcttt ttttattcta ttattgacaa
      361 gtcaatcgtt gacgagtcaa ttattagaaa ggaggaaatt atgtctttag aagagattag
      421 tcacctttta tatcaaatca aattagccga tcaaaaaatc gtccagatct ttgaagaaaa
      481 tatcggtata agtcttacta gatacgagat catgatgaga ctgaaagaag aaaatccatt
      541 gctacaaagc agtttgcaag aaaagttgca gattgatcaa ggagcagtta ctcgtcatct
      601 gaaggtattg gaagcaaatg gctatgtttc gcgtcagaga aatcctcaga acaaccggga
      661 agtgtatgta gcgctaacag aaaaagccca gaagaaaatc gagcattgtg aaatggacca
      721 taaagataca ggttccgtgc tatccccggc tttcagcgat gtagaaatga aacaatttct
      781 aacactttta gataaattga atacccaact ttgcaatata acaacagaaa cgaaagaggt
      841 taataataat ggaacaaaaa aatgattttt caacaattat gactggtaga agatccgttc
      901 gcgtatatga tgaaacatac aaaatcccac acgaagaaat gctggaaatg atcaaagaag
      961 cgacgactgc accttcttct gtcaatatgc aaccatggcg ctttgtggtc gctgaaagcg
     1021 aggaagcaaa agaaatcttg cgtcctttga tccgtttcaa tacgagacaa aatgatactt
     1081 cttctgcaat ggtcatgatt tttggcgata tgcaatgtta cgaatatggc gaagaaatct
     1141 ataaccaagc ttacgaatca gggaagatgc caaaagaagt cagagatcaa caattagctg
     1201 cgatcattcc ttattacaag agtttttcaa gagaagaaat gaacgatgta gtcaaagtcg
     1261 attctagctt agcggctatg caattcatgt tagttgcgcg tgatcatggc tatgaaacaa
     1321 atccaattgg tggattcgaa gcagatcagt tggcagaggc atttggtttg gataaagacc
     1381 gttatgttcc agttattatt ttatcaatag gaaaagcggt agaagaaggt tacgagtctg
     1441 ttcgtttagc accagaaaag atcactacgt tcgaataaaa ggttttcagt tactattcag
     1501 tagctattgc tttttttgaa tcgtgtgtgg taacctaata aaaaaggagg tcggaaaaat
     1561 gactgcatcg atgaaattac gtttcgaact tttgaataac aactaaataa attcaaaaga
     1621 catgtataaa caacaatttc atggatggag tatgtccatt ttttcgaacg acagtagaat
     1681 aggtgaaagc tatgacagat ttggtgattt agtcatagtt atttcgttca gagtaggaaa
     1741 agatgtgatg cagttttttt gcaaacagat ttttctgctc ttttttagta tcgataattg
     1801 ttgttttaca tgaaatagga gtgtaaaaca tatggaaaat ttagcagtaa atataacaaa
     1861 tctacaagtc agctttggca accagctaga actatctatt gattctcttc gtgtctatca
     1921 gcaagatcgt atagggatca taggagaaaa tggtgtcggt aaatcgactt tgctcaaact
     1981 aatagccggt gaactttttc ccgatcatgg gaaaatccaa acagagatca ccttcaacta
     2041 cctgcctcaa ttaacctatc tcgctgaagc aaaggaccta aatttggaat tagccagtca
     2101 tttccagtta agactggaag aaacttcaga gcggaaatgg agcggagggg aagaacgaaa
     2161 gatcgagttg atacgtcttc tttcttctta tgaacaaggg atgcttctag acgagccaac
     2221 aacccatcta gatagaaaaa gtattgatcg actgattgaa gagcttcgtt attattatgg
     2281 tacgctggtt tttgttagtc atgatcgcta ttttctagat gagctagcat cgaaaatctg
     2341 ggaagtaaaa gacggagaaa tccgagagtt ttcggggaat tatagtgcct atctcactca
     2401 aaaggaattg gagaaaaaga ctcagctacg agaagcagag tcgatcatga aagagaaaaa
     2461 acgattggaa aaatcgatcc aagaaaagaa aaaacaagcg gaaaagttgg aaaaagtgtc
     2521 cagtaaaaag aaaaagcaac aaatcagacc ggatcggttg tcttcctcta aacaaaaaga
     2581 cagtgtacaa aaagccatcc aaaagaatgc gaaaacatta gagagaagac tccaaaaaat
     2641 aggagaaaca accaagccgc agcagatgaa acaaatccgt tttccagtac caaaatctct
     2701 tgaactccac agccgctatc ccatcatggg acaaaatgtc caattggaaa gaagtgggag
     2761 aacattactg gtaaatggtg attttcagtt ttctttaggt aaaaaaatcg cgattgtcgg
     2821 tgaaaatggt tcaggtaaga caaccttatt agaacatatc cgcaaacaag gagaaggaat
     2881 ccttctctct ccgaaagtaa gctttcaagt atatcagcaa aagggttatc aaatgacatc
     2941 tgaagaatcc atcattcgtt ttgtcatgag acaaacagag ttttcagaat cgcttgtccg
     3001 tagtttgctg aatcacttag ggtttgctca ggaaactttg acgaaaccgt tatgtacatt
     3061 aagtggggga gaagcgaccc gtctgacgat tgctttgctt tttactaagc caagtaatgt
     3121 gttgctgtta gatgaaccga ctaattttat tgatatggca acgatcgaag ctttagagaa
     3181 gctaatgcaa atatatccgg gaacgatttt gtttacttct catgattctt actttgtcga
     3241 gcgtacggct gatgaagttt atgaaataaa agggcagaaa ataaaaaaag tacttacgag
     3301 aaatttttaa atgtgctacg atgattttcg tgacaaattt aaaggagtgg tacagattgc
     3361 ctacaaataa aaaagaagga ataattttta caacaatgat gtgttttttg atggtcttgg
     3421 ggatgagcgc gtataattta tggctgcatc aagatcttca tttatcaagt ttgttgattg
     3481 gtctagtgcc tggattcgtg gtggctttca ttttggatgt cttcatcatc ggtgtgctgg
     3541 cgaaaaaaat tgcctttaaa ctaccagtaa atccagaaag caaggtccaa atgatcttaa
     3601 ctatttcatg cttgatggtt ttaggaatgg tgacatgtat gtctttattc ggtgtgatca
     3661 tggaacaagg aatacctgat caattattct ctgcttatat gaatgcttgg aaaatgaatg
     3721 tgattgccgc tttaccgttg cagttgatca tcgttggccc gctttcaaga agtgtgctaa
     3781 aagcaattca aagtaatgaa tgatggaaca ctgttatttg aaaaaaggcc ttggcatgct
     3841 ttttgtcata gtctcttgaa tgcagttcta gaaaaatagt gatccgaacg ataggttttg
     3901 gcctgtcgtt cggatcgctt tttcttttcc aactgtattg ctcttttatt gaagataatt
     3961 tgctcttcaa tagatatttc tagaaaggtt ctgtttatcc cttactcaaa aaactgctgc
     4021 atttgttctc ttacttgctg acaccattgg agttcctgct gacaaagcat aattctgcgc
     4081 tggatcacaa cataacgtcc aaattcttgt ttcttgtcta gcgagaggtc attcaatttt
     4141 ttttgatttt tttgcatgat tttgttcagc tgttgttctc tagtgaatag cagtccagta
     4201 gctgttgttt tatcgagcgt cgaaaaagca tagatttttg ctagaaattc atctttttgc
     4261 gtaggagcgg gagtttcctc tttgatccat tcctctacaa gagcacgtcc ttcatcagtc
     4321 aagtggtaga tctttttttg agagtgctcg tctttgtcca aaacggtcac ataaccctgc
     4381 tggtctaact tggcaagcgt tgtatagatc tgactgtgat gggcttccca aaaaattgtg
     4441 atcagctgct tcaattcata cccagaacgt ggtttggata aaagcacgca taataatata
     4501 taggctaaag tattcataaa aatcctacct ctcgtcttat tttctttatt atatcacagt
     4561 aaagtttcca cgttttacat gtgcatattt acatgtaaaa taaatcatgt atgatgctaa
     4621 tagagagaaa gggatggaaa tattggagaa tcaaatagat atacaagaac aaacaaatga
     4681 agaaacaaag gggaaaagtt cagcgctagt tgtagcagct acctgtatga tcgcttttat
     4741 gggagtgggt ctagtagacc caatcttaaa aacgattgct gcacagttaa acgctacgcc
     4801 agctgaaacg accctgttat ttactagtta catgttagtc actggtgtgg tgatgctatt
     4861 tacaggtttc ttatctagtc ggatcggttt gaaaaaaaca ttgatgacag gattgtttat
     4921 catcgttgta ttcgctggtc ttggcggatt atctgggaat atcggaatgc tgattgggtt
     4981 acgtgccggc tggggtgtcg ggaatgcttt atttgtctct actgctttag caacgatcgt
     5041 cagtatttta gttggtaaca cagaaaaagc aatcatgatg tatgaagcag cacttggctg
     5101 cggaatggct gttggccctc tagtcggtgg ggtcttgggc agtggttcat ggcgttatcc
     5161 attttttggg gtagcatttt tgatgttttg cggttttata gccctagcgg tacttttacc
     5221 tgaaactgag aaaccaaaga gaaaagtagg cctttgggaa ggtgtcaaag cgttaagcaa
     5281 tcataaactt cgttcagttg gactaatcgc attgttatat aatttcggat tctttacttt
     5341 acttgcgtat gcgccatttt tattgattgg ctattctgaa ttagaagtcg gttttgtatt
     5401 ttttggctgg ggtgtgcttc tggctattgc ttcgattttc gttgcaccgg ctcttgagcg
     5461 gaagtttacg acttatcgga caattttagc agcatttgtc ttattcatta tttgtttgct
     5521 gttattagga gctggaactt ctatgccagt ccttgtaccg atcagcattg tgttagcagg
     5581 atttttccaa ggaattatca atacactgtt gacgacgatt gctatggaaa taccaggtct
     5641 gcaacgaaac gttgcttcgt ccagctatag ttttgtccgc tttttcggtg gagctttagc
     5701 accatttatt gcaggtgtga ttggtgaaca tattggtgaa agctatgcgt tttattttgc
     5761 aggtgccatt gttcttatca gtgtatgttg tatcatttat caccgtaatt attttgctac
     5821 aaatgaagaa gaataagaaa tcagaggttg tgaaaaagct gtcctgcatc aagtcataag
     5881 aa
//
LOCUS       DAFBSV010000215         4204 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.guided.135, whole genome shotgun sequence.
ACCESSION   DAFBSV010000215 DAFBSV010000000
VERSION     DAFBSV010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4204
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.guided.135"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..391
                     /locus_tag="LLB18_002895"
     CDS             <1..391
                     /locus_tag="LLB18_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBK5245818.1"
                     /translation="AGGIGGALFLLGAKMVSGFDLVSQITGLEKKIEQADVIITGEGR
                     IDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIVLSIHLGPIGLEE
                     AMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            649..2151
                     /gene="eat(A)"
                     /locus_tag="LLB18_002896"
     CDS             649..2151
                     /gene="eat(A)"
                     /locus_tag="LLB18_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBK5245819.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            2179..2745
                     /locus_tag="LLB18_002897"
     CDS             2179..2745
                     /locus_tag="LLB18_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBK5245820.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            2956..4017
                     /locus_tag="LLB18_002898"
     CDS             2956..4017
                     /locus_tag="LLB18_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBK5245821.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            4020..>4204
                     /gene="murQ"
                     /locus_tag="LLB18_002899"
                     /gene_synonym="yfeU"
     CDS             4020..>4204
                     /gene="murQ"
                     /locus_tag="LLB18_002899"
                     /gene_synonym="yfeU"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="catalyzes the cleavage of the lactyl ether moiety
                     of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form
                     N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate;
                     involved in MurNAc dissimilation pathway; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBK5245822.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIES"
BASE COUNT         1458 a          724 c          918 g         1104 t
ORIGIN      
        1 agcaggcggt attggtggag cccttttttt gttgggagcg aagatggttt ctggtttcga
       61 tttagtcagc caaatcactg gattggaaaa aaagatcgaa caagcagatg tcatcattac
      121 aggagaaggg cggatcgatc agcaaacgat ccacggaaaa gttccatacg gtgtagcagt
      181 gcttgcaaaa aaatatcgaa aaccaataat cgctatttgc ggaagtagag accaagagct
      241 agaaggactt tctgattttc tcccaattgt cttaagtatt catttgggtc caataggttt
      301 agaagaagca atggaacaca ggcaaacatt agaaaaaaca aaaatcttag gacagacact
      361 tagcagattt ttcaccatcc tcccgaagta gttgacaaaa tcattttctt tatgctatcg
      421 taatttcaaa tataggacaa agtgagggat ccgtgcattg aaaaattaag tcgattgatg
      481 aaagctgcat tcagactgta ccttgtggag acaaggaagc agtgtgcaga ttttcgggat
      541 tggcttggtt ttttcgatgt atgggtcttt ttgtgtgtat ccaacccttg catcctcttt
      601 agccagttct gaaaatagga ctggtctttt tttacgaggt gatggaaaat gtctaaaatc
      661 gaaataaaaa atctgacatt cggctacgac agccaaggca cattattatt tgaacaagca
      721 aatctaaatt ttgacacaca atggaaacta ggacttatcg gacgaaacgg tcgaggaaag
      781 acaactttac tgaatattct acaaaacaaa ctaccttatc aagggcaagt aatccatcag
      841 caagaatttg cctatttccc gcaacagaca aaagataaag aacgtttaac ctattacgtg
      901 ttaaatgata ttacggattt tgagatatgg gaaatcgaaa gagagctcca attgatgcaa
      961 acagatcctg aaatcttatg gagagaattc agcacactat cggggggaga gaagacaaaa
     1021 gtcctactgg cacttttatt tgtggatgac actcatttcc cgttaatcga tgaaccaacg
     1081 aatcatttgg atatctctgg tagaaaacaa gtagcggctt atttgaaaaa gaaaaaacaa
     1141 ggcttcatcg tggtcagcca tgaccgggga tttatcgatg aagtagtgga ccatgtttta
     1201 gcaatcgaaa aaagtcaact ggaactttat caagggaatt tctctatcta tgaagaacag
     1261 aaaaaacttc gtgatgaatt tgaaatggct caaaatgaaa aattgaaaaa agaagtcagt
     1321 aggctaaaga aaacagcagc tgaaaaagcc gaatggtctc gttcccgaga aggagataaa
     1381 acaaagaaac aagtcggatt catcgatact gaatctagac gagtgaataa aggagcagtg
     1441 ggtgctgatg ctgcacggac gatgaaacga tccaaagcaa tcgtgaatcg gatggagacc
     1501 cagatcagcg agaaagaaaa actattaaaa gatatcgaat atatcgattc tttgacgatg
     1561 aatagccaag cgtctcacca taagcgactt ttaagcgtag aagatcttca attagggtat
     1621 gaaaatctgt tattcgagcc aattcatttt acaatcgagc ctcatcagcg ggtggcgatt
     1681 tcaggtccta acggtgcagg aaagtcatcc attatccatt atcttctggg ggcattcaac
     1741 ggcaaggtta taggagaaaa ataccagcca aaacatctga gcattagtta tgcaagccaa
     1801 aattatgaag acaatcgagg aacgttggcg gaatttgcag agaaaaacca agtagactac
     1861 caagcatttt tgaacaacct ccgaaagctt gggatggaaa gagatgtttt tcataacaag
     1921 atcgagcaga tgagtatggg ccaacggaaa aaagtggaat tggctaaatc tttatcacag
     1981 ccagctgaac tatatacatg ggatgaacca ttgaattatt tggatgtctt caatcaagaa
     2041 caattagaac aactgatctt gaacgtgaaa cctgccatgt tactagtgga acatgatcaa
     2101 accttcctgg ataaagtatc tactgagatt atttctcttg agagaatcta acccttgtaa
     2161 tctcaagaac aacaaggtat ggttaagggg aactttgcca acgaaggaga gaatcacatg
     2221 ctttatgtaa cgagacacgg agaaacaact tggaacgcac aaggattagt ttgcggacgg
     2281 gcagatgtgc cgctgactga aaaaggacag atgcaggcac agaaactagc agaaaaggta
     2341 gtagatttgc ctgttccaat cacgaaaatc atccattccc ctcttcaacg agcaagagat
     2401 acagcacaag cagttgctga tcgtctcagc ttgccgctga ccgttgatga acgattggta
     2461 gaaatggatt ttggggatta tgatggactg ccaagcaaag atgagaactt tcaaaaagca
     2521 cgtttagcgt tcgctgtacg attcccaaat ggggagtcag tcttagatgt gtatgcacgg
     2581 atcgttcctt tattgaaaga atgcatcgaa gacgaagaaa atgtctatct gttagtttgc
     2641 cataatgcct tgataagagt gatcaatgct tattttcatc cgatgcctaa tgaggggttc
     2701 tttacattca tggtagataa tacagaattg gtttcttatg agtaattatg tttttgtgtt
     2761 atttaaataa aatatttcaa ggcactgctt ttgcttagca gtgccttttt taggttatga
     2821 caattctttt gataatataa actcaacctt tagaaatgaa atttaattat tttaataaaa
     2881 gtattgaaat tttgtttctt tagatatata ctctagtcat agaaatgaag acggatacag
     2941 aaaaagaggg ataatatgtt tggcttttca atatttatga acgattcttt gtcagaagag
     3001 aagaaacagt atatccgcca aatggcatcc aatggctttg tcggtatttt cacttccatg
     3061 catataccag aagatgatgt ttcggcatat caaaagcgat tgatcgaact aggaagcgaa
     3121 gcgaaaaaga ataaactaga attgatggtc gatatttcag gagaggcatt ggaacgagcg
     3181 ggtttttcat tagaagatct aacgcctttg aaagcaattg gtgtaacagg tttaagaatg
     3241 gattatcata tttccaatca gcagattgcc gactggtcac atcaattgaa aatcagtttg
     3301 aatgctagca cgatcacgcc taaagatatc gatgaattga aagaagcaga agctgatttc
     3361 tcacagattg aagcttggca taattattat ccacgtcccg aaacagggct ggacaaagaa
     3421 tggtatcaga aaaaaaatca atggctcaaa attcaaggtc tccttgtcca aggttttgta
     3481 ccaggagata cagagttgag aggcccacta tatcaaggat tgccaacttt ggaagaacat
     3541 cgagggatcc atcctcttgc aggcgctcta gatctattag caagtaacac ggatattgtt
     3601 tacatcggag atgcaggtct gtcagaaaac gttcaggagc aatttgcttc tttccaaaaa
     3661 gaacagacag tcttgctcca tacggaacct gtagatgaag aattttacga atatatatta
     3721 gggaagcata cgaatcggca agacgatgca agagatgtca tacgaagcgt agatgcacgt
     3781 tttcgagaga ttccgcctat cccagcaaga aatacagcta cgcgtatgaa agggtctatt
     3841 actttagata acgaaaagta tttgcgctat atgggtgaga tccaattaac caaatatgat
     3901 ttgccagcgg atgaaaaagt gaatgtagta gctaaagtta tcaaagaaga gctaccattg
     3961 atcaaccaaa tcaaagctgg tatgaactat caatttataa gaaaagaagg aagataaaaa
     4021 tgagcaaaat caatttagag aacctaacaa cggaacgcag aaaccaagaa acttttggat
     4081 tagatgagat gagtatttct caagccgttc aactaatgaa caaagaagat cagaaagtgg
     4141 ccgctgcggt tgaaaaagaa ctgacaagta tcgaaccagt gattgctaac acgattgagt
     4201 cctt
//
LOCUS       DAFBSV010000216         2572 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.guided.157, whole genome shotgun sequence.
ACCESSION   DAFBSV010000216 DAFBSV010000000
VERSION     DAFBSV010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2572
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.guided.157"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            495..968
                     /gene="dfrF"
                     /locus_tag="LLB18_002900"
     CDS             495..968
                     /gene="dfrF"
                     /locus_tag="LLB18_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HBK5245823.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            1095..1751
                     /locus_tag="LLB18_002901"
     CDS             1095..1751
                     /locus_tag="LLB18_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HBK5245824.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            1933..2463
                     /locus_tag="LLB18_002902"
     CDS             1933..2463
                     /locus_tag="LLB18_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBK5245825.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
BASE COUNT          929 a          318 c          544 g          781 t
ORIGIN      
        1 aggcggtttg ctatggttta tccctgtggc attgtgcgca gcagagatgg caacggtgaa
       61 aggatgggaa aaaggtgttt cccaaacaaa aagatattaa gaaacagccc atgtttacct
      121 gcttgcaaac aaaagaatat tgctactaga ctaagagata ctacataagt gtgttggtat
      181 ctcttttttg ttgccgtgaa acagcagact atttcatttc tgcttgatta ccttaaaact
      241 tattagtcta tggtttgtca agggcttgtt gcgtgagaaa tgctgaatat caccctttac
      301 aaaacatagg ctgataagta acttttcaaa agcagaaaag aaatggcaat gcttataaca
      361 atatgatata atgcagatga agacaaaaaa ggaatttgtc gagctggtta gttcgagata
      421 attttgagtt tgttaagatg tggtgcactt gatggaatca caggtacgac atcatattat
      481 ggaggatgaa atagatgata ggtttgattg ttgcgaggtc aaagaataat gttataggca
      541 agaatggtaa tataccatgg aaaataaagg gagaacaaaa gcaatttaga gagttaacaa
      601 cgggtaatgt ggttattatg gggcgaaagt cttatgaaga aatcggtcat ccgttgccta
      661 atagaatgaa tattgttgtt tccaccacaa cagagtatca aggagataat ttagtttcag
      721 ttaaatcatt agaagatgca ttattattgg ctaaaggacg agatgtatac atatctggtg
      781 gatatggact atttaaggaa gctttgcaaa tagtagataa aatgtatatc acagaagtag
      841 atttaaatat tgaagatgga gatacattct ttccagaatt tgatatcaat gattttgaag
      901 ttttgatagg ggaaacactt ggtgaggaag tgaaatatac gagaacattt tatgtaagga
      961 aaaaatgaat tgagtaaatt ttggatttag ggtgttttca taaatatatt gctttttatg
     1021 catatataaa ttgttgtaag acaaattcca gtttgtatgg ggcgataaaa tcagaatttg
     1081 agagaggatt gaatatgaat aaggaatggt ctgaacttaa taaaacaatg caggcacaaa
     1141 taaaaaagaa agatacttat aagaggggta ttgatacttt acttacttta cgaagtcagt
     1201 taatacaaac cttagtatct ttcaaagaag aattatgcag agaagatttt aactcaatcc
     1261 ccttcataaa cgctgatggt tatcatagta agacgattgc ttattctatt tggcatattt
     1321 tccgcattga agatatagtt gtgcatacag tgataaatga agatgaacaa gtattttttg
     1381 caggcaatta tcaagagcgt atcaattcac ctatcattac aacaggaaat gaactcatga
     1441 aacagcagat tgcagacttt tcaaaacagc ttaatctgga agaattatat ttatatattt
     1501 tcgaagtatg ggaaagcact gagaaaatgc ttgaacggtt atcttatgat gaattgaaaa
     1561 gaaaaatacc gaaagaaaga aaaggatact tagaatcgtt gaatgtagta aacgacaatg
     1621 aaaaagcaat ttggctgatt gattattggt gtaataaaga tatttgtgga ctaattcaaa
     1681 tgccgttttc aagacattgg attatgcaca cagaagcctg tttgcgtata aagaacaaga
     1741 tacattcata ggcaaaaatt tcagtttgta gaactaagga aattggaatt taaggaggaa
     1801 taaagtatgg ttagtgattt tataagagca gcatttccat ggattttaat gggtttattt
     1861 gtagcaatca gttgttccct tatgagtaaa aaagagaaat aaattcctgt ttgtatttat
     1921 aaaagagaaa aaatgagaaa agtagtttta tttattgcca tgagccttga cggatatatt
     1981 gcggacggta atggtggagt agcttggcta aatggtcatg gaaatgacaa tgaaaacatc
     2041 gacacttata cagaatttac caaagatata gatactgtct taatggggtg gaatacttct
     2101 catcaggttg ttactgaact ttctccgcaa gaatgggtat ataataaatt tacaacttat
     2161 gtattaacac ataaagagtg caattcttcc caacaaattc attttacaag tgaaaatcct
     2221 gttttattat tggaacggct aaaacaagaa gcaggaaagg atatttggat ttgtggcgga
     2281 gcaaatcttg ttcagcagtt ggtaagcaaa aatatgattg ataaatatta catttctgtt
     2341 attcctactc tgttaggaaa tggggttcgt cttttgggca acatagacag ggaaataaag
     2401 ttaaggcttt gtaaaacaca gacttataac ggaataaccg atttgattta tatgcgtaga
     2461 taactagaga gaaacagaaa agctgttaaa ccgacggagc gatccgacca cgttggcggg
     2521 aaaatcctta agatttttgg ctctttgtca aatgatgttg gtaaagagaa at
//
LOCUS       DAFBSV010000217         1777 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.guided.164, whole genome shotgun sequence.
ACCESSION   DAFBSV010000217 DAFBSV010000000
VERSION     DAFBSV010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1777
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.guided.164"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            complement(<1..611)
                     /locus_tag="LLB18_002903"
     CDS             complement(<1..611)
                     /locus_tag="LLB18_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBK5245826.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDR"
     gene            1164..1712
                     /gene="aac(6')"
                     /locus_tag="LLB18_002904"
     CDS             1164..1712
                     /gene="aac(6')"
                     /locus_tag="LLB18_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBK5245827.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          577 a          310 c          350 g          540 t
ORIGIN      
        1 cgatcaatgc acatttttcc gatttggatt cctaatctat ccgtgtagcc tagatcatcg
       61 ccacgagcag aaaaagtaga ttcgacttct ttggataaag catcgccaat acctgcccat
      121 aagtatttat caggtgcttc ggcaataatt gctgtatcaa tgaaggtgtg tacaggtggt
      181 tttgaaggaa agaagagtcc gtccattacg ccttcttcgt tatagatgac acataccgca
      241 gtgacgggcg aacagttcga accaatagtg ggaaaggtga agactggttt agctagtttt
      301 tcaccaatga cttttacagt atcgcaagca cggccaccac cgactgcaaa caggacgtct
      361 gctttttgga cactttcatg ctggatcaac tgttcaatat ttccataagt tgaattaccc
      421 ccgtaccaga gactggcgac aacctctatt tcctgtgtca aagctacttt tattttgttt
      481 tctgcctttg aaagtgcagt cttccctcca atcagcacta cttttgtccc atattctttg
      541 acgattccat ttgctttttc atacgcatct gttccaatgg tataatttgg taagaaaaca
      601 ctttgactca tattcatttc cttctttctt cgttgaaacg ggttaaaatt ttaaagagtg
      661 atcgatctga ctgcggctgt agatggagta gaggtgaacc taagacagga taagtgatga
      721 ataaggtggc atgaacacct tgaaatcatc aataagtatc ctaaaaacga acaagtacaa
      781 aaacattgaa aacgacaata atgaattttt gttcctctta gtatttctac cgattccctt
      841 tgcttttttg taattatcta aaaattctaa aaattaagat tattatatga aaacaggttt
      901 tatttgtcaa ttcataattg gtttttttta aagcaaaaga taatctatat catgatgaac
      961 aaacagagtt ttttcctcca attgatggct ttcctgatct ttcctatttt gaataaagtg
     1021 tttctgtata atttttttat tttataagta agataaataa tgaaagaata gagatactga
     1081 ttggtagcta aagatttttg agcgagaaca tttcgttttt tcaaaaggac tgttagaata
     1141 agcaagaaca agggggaaga cgtatgataa tcagtgaatt tgaccgtaat aatccagtat
     1201 tgaaagatca gctttctgat ttactgagac tgacttggcc ggaagaatat ggagacagct
     1261 cggcagaaga agtagaagaa atgatgaatc cagaacgaat cgcggtagca gcggtagacc
     1321 aagatgagtt agtaggattt attggtgcaa tccctcaata cggtatcaca ggttgggaat
     1381 tgcatccatt agttgtagaa agctcccgac gaaagaacca aataggtact cgattagtca
     1441 attacttaga aaaagaagta gcttccagag gaggaatcac gatttattta ggtacggatg
     1501 atttagacca tggaacaacg ttaagtcaaa cggacctgta tgagcataca tttgataaag
     1561 tggcttccat ccagaacctt cgtgaacatc cgtatgaatt ctatgaaaaa ttaggttata
     1621 aaatcgtagg tgtcttacca aatgcaaatg gctgggacaa accggatatt tggatggcaa
     1681 aaacgattat tcctcgacca aattctcaat aataaaaaga ggttgtgaca gaagtaatca
     1741 gcttcaagaa ataagaagga atttacgaaa attactt
//
LOCUS       DAFBSV010000218         1556 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.guided.171, whole genome shotgun sequence.
ACCESSION   DAFBSV010000218 DAFBSV010000000
VERSION     DAFBSV010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1556
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.guided.171"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            <1..1348
                     /locus_tag="LLB18_002905"
     CDS             <1..1348
                     /locus_tag="LLB18_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HBK5245828.1"
                     /translation="DFILYLKLCNRTESLKKHYTEPWEDEVFRVIIEYNNVPIGYGQI
                     YKMYDELYTDYHYPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAV
                     ILDPHKNNPRAIRAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKY
                     LIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNT
                     NLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLR
                     QMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFE
                     GKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGE
                     DILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          652 a          133 c          257 g          514 t
ORIGIN      
        1 ggattttatt ctttatttaa aactttgcaa cagaaccgaa tcattaaaaa aacattatac
       61 agagccttgg gaagatgaag tttttagagt aattattgaa tataacaatg ttcctattgg
      121 atatggacaa atatataaaa tgtatgatga gttatatact gattatcatt atccaaaaac
      181 tgatgagata gtctatggta tggatcaatt tataggagag ccaaattatt ggagtaaagg
      241 aattggtaca agatatatta aattgatttt tgaatttttg aaaaaagaaa gaaatgctaa
      301 tgcagttatt ttagaccctc ataaaaataa tccaagagca ataagggcat accaaaaatc
      361 tggttttaga attattgaag atttgccaga acatgaatta cacgagggca aaaaagaaga
      421 ttgttattta atggaatata gatatgatga taatgccaca aatgttaagg caatgaaata
      481 tttaattgag cattactttg ataatttcaa agtagatagt attgaaataa tcggtagtgg
      541 ttatgatagt gtggcatatt tagttaataa tgaatacatt tttaaaacaa aatttagtac
      601 taataagaaa aaaggttatg caaaagaaaa agcaatatat aattttttaa atacaaattt
      661 agaaactaat gtaaaaattc ctaatattga atattcgtat attagtgatg aattatctat
      721 actaggttat aaagaaatta aaggaacttt tttaacacca gaaatttatt ctactatgtc
      781 agaagaagaa caaaatttgt taaaacgaga tattgccagt tttttaagac aaatgcacgg
      841 tttagattat acagatatta gtgaatgtac tattgataat aaacaaaatg tattagaaga
      901 gtatatattg ttgcgtgaaa ctatttataa tgatttaact gatatagaaa aagattatat
      961 agaaagtttt atggaaagac taaatgcaac aacagttttt gagggtaaaa agtgtttatg
     1021 ccataatgat tttagttgta atcatctatt gttagatggc aataatagat taactggaat
     1081 aattgatttt ggagattctg gaattataga tgaatattgt gattttatat acttacttga
     1141 agatagtgaa gaagaaatag gaacaaattt tggagaagat atattaagaa tgtatggaaa
     1201 tatagatatt gagaaagcaa aagaatatca agatatagtt gaagaatatt atcctattga
     1261 aactattgtt tatggaatta aaaatattaa acaggaattt atcgaaaatg gtagaaaaga
     1321 aatttataaa aggacttata aagattgatt atataatata tgaaaagcta ttataaaaga
     1381 cattagtatt aaatagttta aaaaaatgaa aaataataaa ggaagtgagt caagtccaga
     1441 ctcctgtgta aaatgctata caatgttttt accatttcta cttatcaaaa ttgatgtatt
     1501 ttcttgaaga ataaatccat tcatcatgta ggtccataag aacggctcca attaag
//
LOCUS       DAFBSV010000219         1219 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-660
            SAMN22135192-rid13229183.guided.186, whole genome shotgun sequence.
ACCESSION   DAFBSV010000219 DAFBSV010000000
VERSION     DAFBSV010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135192
            Sequence Read Archive: SRR16347309
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163154.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163154.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,907
            CDSs (total)                      :: 2,856
            Genes (coding)                    :: 2,794
            CDSs (with protein)               :: 2,794
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 29 of 62
            Pseudo Genes (incomplete)         :: 28 of 62
            Pseudo Genes (internal stop)      :: 18 of 62
            Pseudo Genes (multiple problems)  :: 12 of 62
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135192-rid13229183.guided.186"
                     /isolate="P-660"
                     /isolation_source="rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2017-03"
     gene            111..194
                     /locus_tag="LLB18_002906"
     CDS             111..194
                     /locus_tag="LLB18_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBK5245829.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            319..1056
                     /gene="erm(B)"
                     /locus_tag="LLB18_002907"
     CDS             319..1056
                     /gene="erm(B)"
                     /locus_tag="LLB18_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBK5245830.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          453 a          195 c          200 g          371 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaacca ttttgtgtat aataggaatt
       61 gaagttaaat tagatgctaa aaatttgtaa ttaagaagga gggattcgtc atgttggtat
      121 tccaaatgcg taatgtagat aaaacatcta ctgttttgaa acagactaaa aacagtgatt
      181 acgcagataa ataaatacgt tagattaatt cctaccagtg actaatctta tgacttttta
      241 aacagataac taaaattaca aacaaatcgt ttaacttctg tatttattta cagatgtaat
      301 aacttcagga gtgattacat gaacaaaaat ataaaatatt ctcaaaactt tttaacgagt
      361 gaaaaagtac tcaaccaaat aataaaacaa ttgaatttaa aagaaaccga taccgtttac
      421 gaaattggaa caggtaaagg gcatttaacg acgaaactgg ctaaaataag taaacaggta
      481 acgtctattg aattagacag tcatctattc aacttatcgt cagaaaaatt aaaactgaac
      541 attcgtgtca ctttaattca ccaagatatt ctacagtttc aattccctaa caaacagagg
      601 tataaaattg ttgggagtat tccttaccat ttaagcacac aaattattaa aaaagtggtt
      661 tttgaaagcc atgcgtctga catctatctg attgttgaag aaggattcta caagcgtacc
      721 ttggatattc accgaacact agggttgctc ttgcacactc aagtctcgat tcagcaattg
      781 cttaagctgc cagcggaatg ctttcatcct aaaccaaaag taaacagtgt cttaataaaa
      841 cttacccgcc ataccacaga tgttccagat aaatattgga agctatatac gtactttgtt
      901 tcaaaatggg tcaatcgaga atatcgtcaa ctgtttacta aaaatcagtt tcatcaagca
      961 atgaaacacg ccaaagtaaa caatttaagt accgttactt atgagcaagt attgtctatt
     1021 tttaatagtt atctattatt taacgggagg aaataattct atgagtcgct tttttaaatt
     1081 tggaaagtta cacgttacta aagggaatgg agataaatta ttagatatac tactgacagc
     1141 ttccaagaag ctaaagaggt ccctagcgcc tacggggaat ttgggctcta taatttatgg
     1201 gactgatgaa tcagaattg
//
